A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 Pfam PF14503 YhfZ C-terminal domain 81 310 2.3E-72 T 28-03-2018 IPR032791 Uncharacterised protein YhfZ, C-terminal domain A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 Pfam PF14502 Helix-turn-helix domain 27 74 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 Gene3D G3DSA:1.10.10.10 14 75 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 Gene3D G3DSA:3.40.190.10 77 207 1.7E-37 T 28-03-2018 A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 Gene3D G3DSA:3.40.190.10 208 309 4.0E-12 T 28-03-2018 A21D_RS09295 f9593f64e6363e348ee5e82ef73126ef 310 SUPERFAMILY SSF53850 78 310 1.63E-62 T 28-03-2018 A21D_RS18970 1ac8504c69dd41ba3f422059777d93d0 234 Pfam PF13649 Methyltransferase domain 39 129 3.4E-17 T 28-03-2018 A21D_RS18970 1ac8504c69dd41ba3f422059777d93d0 234 Gene3D G3DSA:3.40.50.150 16 231 7.0E-29 T 28-03-2018 A21D_RS18970 1ac8504c69dd41ba3f422059777d93d0 234 SUPERFAMILY SSF53335 16 201 1.41E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS07465 c70dff42a7ea0fff8be0952e4fc440c2 243 Gene3D G3DSA:3.40.50.1400 116 229 2.1E-18 T 28-03-2018 A21D_RS07465 c70dff42a7ea0fff8be0952e4fc440c2 243 Pfam PF01903 CbiX 9 113 1.4E-25 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A21D_RS07465 c70dff42a7ea0fff8be0952e4fc440c2 243 Pfam PF01903 CbiX 134 236 2.3E-19 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A21D_RS07465 c70dff42a7ea0fff8be0952e4fc440c2 243 Gene3D G3DSA:3.40.50.1400 1 115 3.8E-25 T 28-03-2018 A21D_RS07465 c70dff42a7ea0fff8be0952e4fc440c2 243 SUPERFAMILY SSF53800 1 242 1.74E-47 T 28-03-2018 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Gene3D G3DSA:3.30.300.30 526 632 7.5E-14 T 28-03-2018 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 274 285 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 545 619 3.5E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 SUPERFAMILY SSF56801 40 633 8.9E-125 T 28-03-2018 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Pfam PF00501 AMP-binding enzyme 101 532 1.8E-44 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 41 95 9.3E-10 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Gene3D G3DSA:3.40.50.980 280 440 7.5E-24 T 28-03-2018 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 Gene3D G3DSA:3.40.50.980 90 279 2.5E-28 T 28-03-2018 A21D_RS03360 d7d4d4ce8acacd5394281b2e4a4b471b 661 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 9 658 1.3E-254 T 28-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 Gene3D G3DSA:3.90.1820.10 1 275 8.0E-63 T 28-03-2018 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 Gene3D G3DSA:3.90.1820.10 276 441 2.3E-42 T 28-03-2018 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 SUPERFAMILY SSF51735 3 164 1.47E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 Pfam PF02056 Family 4 glycosyl hydrolase 5 183 4.7E-59 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 SUPERFAMILY SSF56327 168 441 4.32E-88 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 8.4E-54 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08935 8b32140344db99d51e5341fd1bbdd808 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 416 2.3E-50 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS09210 82421d04b65cacb55fcd8ef4892a43cb 139 Pfam PF17369 Family of unknown function (DUF5391) 2 129 1.1E-34 T 28-03-2018 IPR020204 Uncharacterised protein family, YxaJ A21D_RS09210 82421d04b65cacb55fcd8ef4892a43cb 139 ProDom PD086672 YXAJ MEMBRANE TRANSMEMBRANE 11 78 3.0E-13 T 28-03-2018 IPR020204 Uncharacterised protein family, YxaJ A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 493 602 2.1E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Gene3D G3DSA:3.30.450.20 35 181 7.5E-14 T 28-03-2018 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SMART SM00091 267 333 1.4E-9 T 28-03-2018 IPR000014 PAS domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Pfam PF00672 HAMP domain 208 251 2.2E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Gene3D G3DSA:3.30.450.20 253 376 1.3E-20 T 28-03-2018 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SUPERFAMILY SSF47384 366 447 2.35E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Gene3D G3DSA:1.10.287.130 377 443 1.3E-17 T 28-03-2018 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 263 380 1.1E-9 T 28-03-2018 IPR000014 PAS domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 543 1.2E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 582 1.2E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 601 1.2E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 557 1.2E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SMART SM00304 208 260 4.6E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SMART SM00388 380 447 4.6E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SUPERFAMILY SSF55874 436 603 6.55E-51 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SUPERFAMILY SSF55785 254 372 2.09E-13 T 28-03-2018 IPR000014 PAS domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SMART SM00387 492 604 4.7E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Gene3D G3DSA:3.30.565.10 451 610 2.9E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SUPERFAMILY SSF103190 47 179 4.16E-5 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Pfam PF00989 PAS fold 269 371 1.2E-11 T 28-03-2018 IPR013767 PAS fold GO:0006355 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 SUPERFAMILY SSF158472 208 257 3.92E-11 T 28-03-2018 A21D_RS07385 eb6c6168d392c8d48480168cceea7205 610 Pfam PF00512 His Kinase A (phospho-acceptor) domain 381 446 6.2E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS09235 983a76c89367d847dfa05302d9e6ecd9 388 SUPERFAMILY SSF103473 1 383 7.46E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS09235 983a76c89367d847dfa05302d9e6ecd9 388 Gene3D G3DSA:1.20.1250.20 201 387 1.3E-15 T 28-03-2018 A21D_RS09235 983a76c89367d847dfa05302d9e6ecd9 388 Gene3D G3DSA:1.20.1250.20 1 189 3.1E-25 T 28-03-2018 A21D_RS09235 983a76c89367d847dfa05302d9e6ecd9 388 Pfam PF07690 Major Facilitator Superfamily 7 334 1.6E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 222 30.706 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 Pfam PF14622 Ribonuclease-III-like 16 147 2.1E-36 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 ProSitePatterns PS00517 Ribonuclease III family signature. 42 50 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 Pfam PF00035 Double-stranded RNA binding motif 159 224 1.1E-17 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 SMART SM00358 159 226 2.9E-24 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 SMART SM00535 18 153 8.7E-54 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 Gene3D G3DSA:1.10.1520.10 2 151 4.7E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 Gene3D G3DSA:3.30.160.20 157 227 6.3E-23 T 28-03-2018 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 224 8.1E-79 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 SUPERFAMILY SSF54768 154 226 5.97E-24 T 28-03-2018 A21D_RS18095 e88025b9e90923ccc19e3de0fd457115 227 SUPERFAMILY SSF69065 2 161 8.89E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS18325 65e28f8911168ca50d91d3dddef2de71 258 Pfam PF01479 S4 domain 183 227 1.2E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS18325 65e28f8911168ca50d91d3dddef2de71 258 SUPERFAMILY SSF55174 179 252 2.09E-26 T 28-03-2018 A21D_RS18325 65e28f8911168ca50d91d3dddef2de71 258 SUPERFAMILY SSF55174 36 127 2.09E-26 T 28-03-2018 A21D_RS18325 65e28f8911168ca50d91d3dddef2de71 258 SMART SM00363 182 242 5.7E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS18325 65e28f8911168ca50d91d3dddef2de71 258 Gene3D G3DSA:3.10.290.10 175 258 5.6E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14350 3b4c187ee3c07d092b7b319048aa9905 276 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 191 208 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site A21D_RS14350 3b4c187ee3c07d092b7b319048aa9905 276 Pfam PF01618 MotA/TolQ/ExbB proton channel family 107 221 4.3E-23 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 Gene3D G3DSA:3.20.20.70 2 328 4.5E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 SUPERFAMILY SSF102114 5 377 1.83E-113 T 28-03-2018 A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 SMART SM00729 4 223 9.2E-59 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 Pfam PF04055 Radical SAM superfamily 9 176 9.7E-23 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 Pfam PF06969 HemN C-terminal domain 304 365 1.6E-11 T 28-03-2018 IPR010723 HemN, C-terminal A21D_RS15625 1249434d044fb6d5fce51a34619d4ad8 383 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 6 364 2.5E-117 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 Gene3D G3DSA:3.40.190.10 91 176 4.2E-13 T 28-03-2018 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 SUPERFAMILY SSF46785 2 110 4.44E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.7E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 Gene3D G3DSA:3.40.190.10 177 256 5.4E-10 T 28-03-2018 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 Gene3D G3DSA:1.10.10.10 1 83 4.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 Pfam PF03466 LysR substrate binding domain 87 282 1.0E-32 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS11220 e2caccf8512ef77c36d158bac675a5d2 289 SUPERFAMILY SSF53850 88 283 4.62E-30 T 28-03-2018 A21D_RS16115 e29901b1fff4accc37f1ebb8b4764b48 450 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 441 28.738 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16115 e29901b1fff4accc37f1ebb8b4764b48 450 Pfam PF13742 OB-fold nucleic acid binding domain 6 101 1.3E-30 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A21D_RS16115 e29901b1fff4accc37f1ebb8b4764b48 450 Gene3D G3DSA:2.40.50.140 12 102 5.0E-8 T 28-03-2018 A21D_RS16115 e29901b1fff4accc37f1ebb8b4764b48 450 Pfam PF02601 Exonuclease VII, large subunit 124 438 6.5E-97 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A21D_RS16115 e29901b1fff4accc37f1ebb8b4764b48 450 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 340 7.3E-135 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 PIRSF PIRSF000094 2 258 5.3E-97 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 2.6E-79 T 28-03-2018 A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 Gene3D G3DSA:3.40.50.720 1 256 1.4E-40 T 28-03-2018 A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 SUPERFAMILY SSF51735 6 255 5.81E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS05420 a484de44afaa9d36b87a3937317c91e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS10800 33a2b99565ac6e01efd7c84ecdc99b74 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 321 1.4E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10800 33a2b99565ac6e01efd7c84ecdc99b74 322 SUPERFAMILY SSF161098 97 303 4.97E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10800 33a2b99565ac6e01efd7c84ecdc99b74 322 Gene3D G3DSA:1.10.3720.10 2 309 3.7E-49 T 28-03-2018 A21D_RS02230 8900cfd11f8454b865df88ceb67123f6 102 Gene3D G3DSA:1.10.10.10 61 101 1.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02230 8900cfd11f8454b865df88ceb67123f6 102 Gene3D G3DSA:1.10.10.10 7 60 4.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02230 8900cfd11f8454b865df88ceb67123f6 102 SUPERFAMILY SSF48295 63 97 8.37E-5 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A21D_RS02230 8900cfd11f8454b865df88ceb67123f6 102 Pfam PF01527 Transposase 9 57 2.8E-7 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A21D_RS02230 8900cfd11f8454b865df88ceb67123f6 102 SUPERFAMILY SSF46689 7 58 8.24E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Gene3D G3DSA:1.10.10.10 258 328 8.8E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 2.1E-145 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 337 169.107 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 2.2E-35 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 SUPERFAMILY SSF46785 258 328 2.52E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Gene3D G3DSA:3.40.50.300 19 182 2.3E-29 T 28-03-2018 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 2.8E-116 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 Gene3D G3DSA:1.10.8.60 185 255 2.5E-28 T 28-03-2018 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 SUPERFAMILY SSF52540 21 253 9.22E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 327 7.0E-30 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A21D_RS15270 f1ce7a715d5dcea9f42dfda4802789b6 337 SMART SM00382 52 185 7.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 5.9E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 5.9E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 5.9E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 Pfam PF00210 Ferritin-like domain 6 142 1.2E-32 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 PIRSF PIRSF005900 1 145 2.2E-47 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 Gene3D G3DSA:1.20.1260.10 1 145 5.9E-48 T 28-03-2018 IPR012347 Ferritin-related A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A21D_RS14985 32b5e60610edf3033b6dd932872cb9d0 145 SUPERFAMILY SSF47240 3 143 2.08E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PIRSF PIRSF000729 1 362 4.3E-127 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 Gene3D G3DSA:3.40.1160.10 1 262 8.5E-59 T 28-03-2018 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 SUPERFAMILY SSF53633 4 255 3.67E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 SUPERFAMILY SSF88697 277 360 4.42E-15 T 28-03-2018 IPR015947 PUA-like domain A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 360 1.4E-125 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 Pfam PF01472 PUA domain 277 337 7.9E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 SMART SM00359 277 358 3.2E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 Pfam PF00696 Amino acid kinase family 4 232 3.2E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 259 35.659 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 2.8E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 2.8E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 2.8E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 2.8E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 2.8E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS01470 8599445315aa4007ed98a06c5b5ebca2 363 Gene3D G3DSA:2.30.130.10 275 360 1.7E-15 T 28-03-2018 IPR002478 PUA domain GO:0003723 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 21 234 3.3E-30 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 502 239.095 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 8 499 2.0E-201 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 252 445 3.8E-29 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 PIRSF PIRSF006005 2 502 3.4E-211 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04145 f6f968a54839b58ca08af00acaa8d166 502 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 264 281 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 458 7.0E-205 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 Gene3D G3DSA:3.20.20.70 2 486 5.8E-117 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 Pfam PF00571 CBS domain 97 144 4.5E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 Pfam PF00571 CBS domain 153 204 2.9E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SMART SM00116 98 148 2.0E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SMART SM00116 161 209 3.6E-8 T 28-03-2018 IPR000644 CBS domain A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 476 8.0E-170 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SUPERFAMILY SSF51412 5 92 9.03E-130 T 28-03-2018 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SUPERFAMILY SSF51412 220 480 9.03E-130 T 28-03-2018 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 PIRSF PIRSF000130 1 489 1.5E-211 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SMART SM01240 9 476 0.0 T 28-03-2018 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 SUPERFAMILY SSF54631 65 208 2.02E-29 T 28-03-2018 A21D_RS07185 33638d3720c37ca5dfdb59e4264a4fbd 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 489 87.307 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A21D_RS06765 43986890ae30d5132206454240d8af1f 96 Gene3D G3DSA:3.30.1120.40 1 83 7.0E-37 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A21D_RS06765 43986890ae30d5132206454240d8af1f 96 SUPERFAMILY SSF160537 1 89 6.02E-34 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A21D_RS06765 43986890ae30d5132206454240d8af1f 96 Pfam PF04026 SpoVG 1 82 2.3E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A21D_RS06765 43986890ae30d5132206454240d8af1f 96 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.237 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 288 34.995 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 288 8.2E-107 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 Gene3D G3DSA:3.40.1380.10 63 177 3.1E-40 T 28-03-2018 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 8.6E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 8.6E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 8.6E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 8.6E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 Gene3D G3DSA:1.10.287.80 178 269 2.4E-30 T 28-03-2018 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 SUPERFAMILY SSF52943 2 288 6.54E-90 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 Pfam PF00231 ATP synthase 3 288 1.2E-96 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04540 29f252d18d3849954e807ec379099c90 289 Gene3D G3DSA:1.10.287.80 2 62 3.3E-17 T 28-03-2018 A21D_RS04795 250837ba28a36a66a0fe1aec961fd0fb 170 Pfam PF08741 YwhD family 9 168 4.6E-75 T 28-03-2018 IPR014852 Uncharacterised protein YwhD A21D_RS19110 b2c1613252e7f247654022bfa39b28b9 45 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 23 43 7.3E-10 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS19110 b2c1613252e7f247654022bfa39b28b9 45 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 25 45 1.2E-10 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 72 158 7.5E-9 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 184 251 2.6E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 SUPERFAMILY SSF81648 21 155 8.63E-28 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 Gene3D G3DSA:1.20.810.10 14 160 8.9E-27 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 Gene3D G3DSA:1.10.760.10 161 260 1.7E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 SUPERFAMILY SSF46626 142 255 3.25E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS16670 58ae225c3eaf97b2b6c1432a6fa05add 260 PIRSF PIRSF036636 1 257 3.0E-138 T 28-03-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 151 179 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 PIRSF PIRSF000112 1 362 7.5E-100 T 28-03-2018 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 350 1.1E-64 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 Gene3D G3DSA:3.40.50.1970 2 161 6.2E-31 T 28-03-2018 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 242 262 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 SUPERFAMILY SSF56796 3 357 3.93E-92 T 28-03-2018 A21D_RS11445 511eb1dbeeab41b03ae17e50e9d38ecd 363 Gene3D G3DSA:1.20.1090.10 162 363 1.4E-34 T 28-03-2018 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 Pfam PF00248 Aldo/keto reductase family 29 258 3.5E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 Gene3D G3DSA:3.20.20.100 1 274 7.1E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PRINTS PR00069 Aldo-keto reductase signature 39 63 2.7E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.7E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.7E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PRINTS PR00069 Aldo-keto reductase signature 95 113 2.7E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 2.7E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 SUPERFAMILY SSF51430 5 265 1.13E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PIRSF PIRSF000097 115 273 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 PIRSF PIRSF000097 1 117 7.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS12445 8972ae3a27ba2f371d58976d99df82f7 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 Gene3D G3DSA:1.20.1250.20 193 400 9.6E-30 T 28-03-2018 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 SUPERFAMILY SSF103473 1 387 2.62E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 Gene3D G3DSA:1.20.1250.20 1 192 6.4E-36 T 28-03-2018 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 Pfam PF07690 Major Facilitator Superfamily 2 259 4.0E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 PRINTS PR01035 Tetracycline resistance protein signature 38 57 8.5E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 PRINTS PR01035 Tetracycline resistance protein signature 333 356 8.5E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 PRINTS PR01035 Tetracycline resistance protein signature 69 93 8.5E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 PRINTS PR01035 Tetracycline resistance protein signature 126 148 8.5E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS09025 f7cb89ce2ba26dee8f12905bef14e521 403 PRINTS PR01035 Tetracycline resistance protein signature 96 117 8.5E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 Pfam PF01555 DNA methylase 47 233 5.9E-26 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 SUPERFAMILY SSF53335 4 242 7.88E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 24 38 9.2E-24 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 197 215 9.2E-24 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 178 195 9.2E-24 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 50 70 9.2E-24 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 220 240 9.2E-24 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A21D_RS10325 6826ef7ba54aa82c2da67b9db3db85b1 259 Gene3D G3DSA:3.40.50.150 2 246 1.4E-44 T 28-03-2018 A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 SMART SM00448 6 121 8.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 Gene3D G3DSA:1.10.10.10 134 246 8.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 Gene3D G3DSA:3.40.50.2300 5 133 6.0E-27 T 28-03-2018 A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 PIRSF PIRSF006171 4 238 6.1E-76 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 SUPERFAMILY SSF46785 185 238 4.57E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 SUPERFAMILY SSF52172 5 137 3.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS02495 f6564b808dc85c1cc464da6e3eaf6f61 246 Pfam PF00072 Response regulator receiver domain 8 121 1.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17840 70cc4dd1a3fac4a3436e1ddf11568956 290 PIRSF PIRSF003092 2 290 1.8E-82 T 28-03-2018 IPR025501 ATP binding protein MinD A21D_RS17840 70cc4dd1a3fac4a3436e1ddf11568956 290 SUPERFAMILY SSF52540 22 285 5.23E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17840 70cc4dd1a3fac4a3436e1ddf11568956 290 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 23 260 2.6E-19 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A21D_RS17840 70cc4dd1a3fac4a3436e1ddf11568956 290 Gene3D G3DSA:3.40.50.300 21 266 2.2E-50 T 28-03-2018 A21D_RS17815 2982d966f8bd9e712ec7d86f95b7e820 168 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 7 164 27.62 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A21D_RS17815 2982d966f8bd9e712ec7d86f95b7e820 168 SUPERFAMILY SSF64438 10 166 6.59E-48 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A21D_RS17815 2982d966f8bd9e712ec7d86f95b7e820 168 Pfam PF03975 CheD chemotactic sensory transduction 54 159 4.4E-34 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:2.70.98.10 233 480 9.0E-68 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Pfam PF17451 Glycosyl hydrolase 101 beta sandwich domain 757 877 1.0E-34 T 28-03-2018 IPR035364 Glycosyl hydrolase 101, beta-sandwich domain A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:3.20.20.80 483 759 2.3E-110 T 28-03-2018 A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:2.60.120.560 22 221 1.4E-13 T 28-03-2018 A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 470 750 1.1E-115 T 28-03-2018 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:2.60.120.260 913 1079 4.1E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:2.60.120.260 1080 1267 1.4E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS01395 3011a06b5da08a723739760b8dd897de 1267 Gene3D G3DSA:2.60.40.1180 760 904 8.0E-47 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Gene3D G3DSA:3.40.50.2300 182 337 4.2E-35 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 9.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 9.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Gene3D G3DSA:1.10.260.40 18 57 1.7E-20 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Gene3D G3DSA:1.10.10.60 2 17 0.17 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 SUPERFAMILY SSF47413 2 61 6.0E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 SUPERFAMILY SSF53822 62 333 1.05E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Gene3D G3DSA:3.40.50.2300 58 181 1.0E-33 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 SMART SM00354 2 73 1.0E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Pfam PF13377 Periplasmic binding protein-like domain 174 332 1.3E-25 T 28-03-2018 A21D_RS13135 b696e6c420398cd18e4a17d2ac5606f3 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 1.5E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:3.40.930.10 492 641 1.1E-19 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 SUPERFAMILY SSF52794 392 476 4.5E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:1.10.1790.10 272 384 6.2E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:1.10.1790.10 175 271 3.9E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:3.40.50.2300 390 480 4.5E-15 T 28-03-2018 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Pfam PF00874 PRD domain 191 266 9.4E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Pfam PF00874 PRD domain 290 379 9.0E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 SUPERFAMILY SSF63520 282 384 6.02E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:1.10.10.10 6 68 1.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 SUPERFAMILY SSF55804 493 638 2.62E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Gene3D G3DSA:1.10.10.10 87 157 8.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Pfam PF08279 HTH domain 13 65 1.6E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 SUPERFAMILY SSF63520 185 268 1.57E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02370 1f5862cfb0c2a84af4ee8cdcb4234d56 645 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 496 639 3.7E-16 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS18820 3d73a417da497e9c00998c6285ad425e 263 Gene3D G3DSA:3.40.109.10 15 261 1.9E-53 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A21D_RS18820 3d73a417da497e9c00998c6285ad425e 263 PIRSF PIRSF005426 14 261 6.1E-83 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 A21D_RS18820 3d73a417da497e9c00998c6285ad425e 263 SUPERFAMILY SSF55469 17 258 3.4E-63 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A21D_RS18820 3d73a417da497e9c00998c6285ad425e 263 Pfam PF00881 Nitroreductase family 21 178 4.0E-19 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 SUPERFAMILY SSF52151 4 121 4.45E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 SUPERFAMILY SSF52151 188 308 4.45E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 PIRSF PIRSF000446 1 308 3.4E-111 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 Gene3D G3DSA:3.30.70.250 141 182 7.7E-22 T 28-03-2018 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 SUPERFAMILY SSF55048 127 195 7.59E-17 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 303 2.6E-46 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 Gene3D G3DSA:3.40.366.10 3 140 1.9E-41 T 28-03-2018 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 8.1E-110 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 Gene3D G3DSA:3.40.366.10 183 307 2.2E-30 T 28-03-2018 A21D_RS18110 e7539110afa169dedcb1aa4a85e93f94 313 Pfam PF00698 Acyl transferase domain 6 275 5.4E-49 T 28-03-2018 IPR014043 Acyl transferase A21D_RS16700 d149677a68b58e7a96d2881b6c6968af 114 SUPERFAMILY SSF101386 5 106 7.69E-27 T 28-03-2018 A21D_RS16700 d149677a68b58e7a96d2881b6c6968af 114 Gene3D G3DSA:1.10.3420.10 1 112 1.1E-25 T 28-03-2018 A21D_RS16700 d149677a68b58e7a96d2881b6c6968af 114 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 106 7.9E-21 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS16700 d149677a68b58e7a96d2881b6c6968af 114 PIRSF PIRSF029904 3 113 1.6E-50 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.86 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 9.7E-228 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 403 3.5E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 1.2E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 SUPERFAMILY SSF56281 11 423 4.19E-93 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 Gene3D G3DSA:3.60.15.10 4 448 4.1E-63 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 SMART SM00849 21 215 1.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS18690 dfe462a501a609cf8585635196ac8d8a 555 PIRSF PIRSF004803 1 555 1.8E-246 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 Pfam PF00005 ABC transporter 18 174 5.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 SUPERFAMILY SSF52540 1 235 4.37E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 SMART SM00382 27 223 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 Gene3D G3DSA:3.40.50.300 1 244 5.9E-60 T 28-03-2018 A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS01170 e9587b543031f003738c7eeabe449b3f 256 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 1.7E-108 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 SMART SM00729 57 265 1.4E-15 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 PIRSF PIRSF005963 1 311 1.0E-141 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 TIGRFAM TIGR00510 lipA: lipoyl synthase 4 291 1.3E-122 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 Gene3D G3DSA:3.20.20.70 9 273 1.1E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 149.916 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 SUPERFAMILY SSF102114 21 287 1.02E-61 T 28-03-2018 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 45 3.3E-11 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A21D_RS04335 8edcd418f928bbdf2d9dddeb8162fdf9 314 Pfam PF04055 Radical SAM superfamily 64 223 4.9E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 139 170 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 SUPERFAMILY SSF51735 2 166 1.4E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 Pfam PF02056 Family 4 glycosyl hydrolase 4 185 2.8E-63 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 SUPERFAMILY SSF56327 171 433 9.18E-84 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 4 19 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 96 109 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 75 91 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 7.3E-47 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 409 5.4E-46 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 Gene3D G3DSA:3.90.1820.10 1 264 5.1E-60 T 28-03-2018 A21D_RS04385 950b2120b4889441741de8ca801b55fc 433 Gene3D G3DSA:3.90.1820.10 265 433 4.4E-52 T 28-03-2018 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 315 1.1E-154 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 SUPERFAMILY SSF52096 5 315 4.23E-102 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.5E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 1.4E-65 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 50.048 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14550 8a22e747a19268ec750c12fa32e91092 318 Gene3D G3DSA:3.90.226.10 1 287 1.2E-66 T 28-03-2018 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 Gene3D G3DSA:3.30.160.20 207 289 4.0E-31 T 28-03-2018 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 Pfam PF00472 RF-1 domain 210 319 4.8E-40 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.878 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 354 5.7E-172 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 SUPERFAMILY SSF75620 8 351 2.49E-135 T 28-03-2018 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 SMART SM00937 63 177 5.3E-64 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 Pfam PF03462 PCRF domain 8 202 2.8E-73 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 A21D_RS04655 d96b47de03b8c1789d90fecd4adfc07e 356 Gene3D G3DSA:1.20.58.410 2 94 5.3E-17 T 28-03-2018 A21D_RS15560 a2189d0fad72492b437e5be0a9bfd910 191 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 181 4.2E-54 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 A21D_RS15560 a2189d0fad72492b437e5be0a9bfd910 191 SUPERFAMILY SSF109604 4 179 8.08E-34 T 28-03-2018 A21D_RS15560 a2189d0fad72492b437e5be0a9bfd910 191 SMART SM00471 14 141 2.8E-9 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS15560 a2189d0fad72492b437e5be0a9bfd910 191 Pfam PF01966 HD domain 18 130 8.1E-17 T 28-03-2018 IPR006674 HD domain A21D_RS15560 a2189d0fad72492b437e5be0a9bfd910 191 Gene3D G3DSA:1.10.3210.10 1 186 3.0E-27 T 28-03-2018 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 Pfam PF00312 Ribosomal protein S15 8 88 9.7E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 SMART SM01387 8 88 5.5E-52 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-37 T 28-03-2018 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 SUPERFAMILY SSF47060 3 89 5.3E-37 T 28-03-2018 IPR009068 S15/NS1, RNA-binding A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.161 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 9.4E-42 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17705 c6415074b2cdfa1fcaf4b5ab6dd91415 89 Gene3D G3DSA:1.10.287.10 2 89 7.0E-36 T 28-03-2018 A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 462 1.1E-82 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 90 112 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 Gene3D G3DSA:3.40.190.10 178 310 1.4E-35 T 28-03-2018 A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 SUPERFAMILY SSF53850 38 535 1.14E-130 T 28-03-2018 A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 PIRSF PIRSF002741 1 540 4.2E-116 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 Gene3D G3DSA:3.10.105.10 311 513 2.6E-52 T 28-03-2018 A21D_RS04490 3934bf4f2aa0e76dfa8c6888cf78c4ac 541 Gene3D G3DSA:3.90.76.10 66 177 3.6E-33 T 28-03-2018 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 Gene3D G3DSA:1.10.340.30 19 122 6.0E-25 T 28-03-2018 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 159 2.4E-11 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 PIRSF PIRSF001435 1 213 1.4E-65 T 28-03-2018 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 SUPERFAMILY SSF48150 6 210 8.64E-52 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 SMART SM00478 37 192 3.9E-23 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS08620 cd970915457e3f136058c52f9aac6f46 214 Gene3D G3DSA:1.10.1670.10 123 213 6.1E-21 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Gene3D G3DSA:2.60.40.420 6 178 2.6E-31 T 28-03-2018 IPR008972 Cupredoxin A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 SUPERFAMILY SSF49503 370 514 2.06E-36 T 28-03-2018 IPR008972 Cupredoxin A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Pfam PF07731 Multicopper oxidase 386 514 3.4E-21 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Pfam PF07732 Multicopper oxidase 50 87 1.1E-4 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Pfam PF00394 Multicopper oxidase 245 312 2.8E-5 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 SUPERFAMILY SSF49503 8 181 1.35E-24 T 28-03-2018 IPR008972 Cupredoxin A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Gene3D G3DSA:2.60.40.420 363 516 3.5E-34 T 28-03-2018 IPR008972 Cupredoxin A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 Gene3D G3DSA:2.60.40.420 179 362 3.3E-35 T 28-03-2018 IPR008972 Cupredoxin A21D_RS03645 5b19e57ffb13101c2bbb868f7c414a56 516 SUPERFAMILY SSF49503 185 313 1.47E-26 T 28-03-2018 IPR008972 Cupredoxin A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Pfam PF01842 ACT domain 456 518 4.6E-8 T 28-03-2018 IPR002912 ACT domain A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 SUPERFAMILY SSF51735 99 283 6.27E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 SUPERFAMILY SSF52283 15 130 1.36E-38 T 28-03-2018 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 282 1.3E-62 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Gene3D G3DSA:3.30.70.260 450 527 6.9E-16 T 28-03-2018 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Gene3D G3DSA:3.40.50.720 112 285 4.3E-58 T 28-03-2018 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Gene3D G3DSA:3.30.1330.90 318 449 1.5E-33 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 SUPERFAMILY SSF143548 321 450 9.68E-35 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 4 528 1.2E-206 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 SUPERFAMILY SSF55021 445 524 4.2E-16 T 28-03-2018 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 314 1.2E-39 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 Gene3D G3DSA:3.40.50.720 3 111 2.7E-34 T 28-03-2018 A21D_RS12500 657a6453ceaca969f2b784a270a77209 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 585 3.5E-234 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 452 2.8E-141 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SUPERFAMILY SSF47819 514 590 1.48E-24 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF00270 DEAD/DEAH box helicase 20 182 6.1E-22 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF14493 Helix-turn-helix domain 617 705 4.2E-22 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SMART SM00341 513 593 5.7E-18 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF00271 Helicase conserved C-terminal domain 214 321 2.8E-18 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SUPERFAMILY SSF46785 394 539 1.63E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF16124 RecQ zinc-binding 333 395 7.5E-16 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SMART SM00487 14 209 4.5E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SMART SM00956 403 506 4.0E-41 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Gene3D G3DSA:1.10.10.10 345 508 8.7E-47 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF00570 HRDC domain 517 583 1.1E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Pfam PF09382 RQC domain 400 502 7.5E-33 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Gene3D G3DSA:1.10.150.80 509 595 4.7E-27 T 28-03-2018 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SMART SM00490 241 322 1.3E-27 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 SUPERFAMILY SSF52540 58 344 1.53E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Gene3D G3DSA:3.40.50.300 3 207 4.3E-35 T 28-03-2018 A21D_RS09125 bbb18d593b726ed79537dafb769726d5 711 Gene3D G3DSA:3.40.50.300 208 344 3.1E-33 T 28-03-2018 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 SMART SM00490 467 548 2.6E-13 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Pfam PF13091 PLD-like domain 46 177 2.7E-15 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Gene3D G3DSA:3.40.50.300 430 782 1.0E-24 T 28-03-2018 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Gene3D G3DSA:3.40.50.300 212 392 7.0E-25 T 28-03-2018 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Pfam PF04851 Type III restriction enzyme, res subunit 224 375 2.0E-31 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 SMART SM00487 222 402 9.5E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 SUPERFAMILY SSF56024 38 184 4.93E-15 T 28-03-2018 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Pfam PF11907 Domain of unknown function (DUF3427) 687 960 1.4E-85 T 28-03-2018 IPR021835 Protein of unknown function DUF3427 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Gene3D G3DSA:3.30.870.10 25 186 3.4E-17 T 28-03-2018 A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 Pfam PF00271 Helicase conserved C-terminal domain 449 546 1.9E-14 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS07675 0c45b93eacc920d5efc1ffab0e8d8aa7 965 SUPERFAMILY SSF52540 271 569 9.91E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18070 2559e1827129da067e3a67e159975564 106 SUPERFAMILY SSF88659 1 99 1.08E-34 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18070 2559e1827129da067e3a67e159975564 106 Gene3D G3DSA:1.10.10.10 1 106 1.5E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18070 2559e1827129da067e3a67e159975564 106 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 101 5.9E-40 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A21D_RS18070 2559e1827129da067e3a67e159975564 106 Hamap MF_00245 UPF0122 protein . 2 102 21.989 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A21D_RS13970 f0334846ab5412d6f65f432c4dac6049 411 Pfam PF01548 Transposase 18 149 1.3E-19 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A21D_RS13970 f0334846ab5412d6f65f432c4dac6049 411 Pfam PF02371 Transposase IS116/IS110/IS902 family 253 336 1.7E-14 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Gene3D G3DSA:2.60.260.20 255 367 3.2E-31 T 28-03-2018 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Gene3D G3DSA:2.60.260.20 201 253 8.4E-13 T 28-03-2018 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Pfam PF00684 DnaJ central domain 144 208 6.3E-14 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Pfam PF00226 DnaJ domain 5 66 2.2E-26 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Gene3D G3DSA:1.10.287.110 1 112 2.0E-37 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 41.846 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Pfam PF01556 DnaJ C terminal domain 117 334 7.4E-45 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 Gene3D G3DSA:2.10.230.10 141 200 2.1E-16 T 28-03-2018 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SUPERFAMILY SSF49493 260 345 4.71E-25 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SUPERFAMILY SSF46565 2 103 7.33E-37 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SMART SM00271 4 61 1.0E-29 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SUPERFAMILY SSF49493 111 135 5.89E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SUPERFAMILY SSF49493 214 266 5.89E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 350 1.0E-143 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 PRINTS PR00625 DnaJ domain signature 61 80 1.5E-31 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 PRINTS PR00625 DnaJ domain signature 25 40 1.5E-31 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 PRINTS PR00625 DnaJ domain signature 41 61 1.5E-31 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 PRINTS PR00625 DnaJ domain signature 7 25 1.5E-31 T 28-03-2018 IPR001623 DnaJ domain A21D_RS15645 0d8b2e0335a64019c932be859d71b645 375 SUPERFAMILY SSF57938 131 212 6.15E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 SUPERFAMILY SSF63999 4 130 3.92E-31 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 Gene3D G3DSA:3.40.50.10240 2 118 2.2E-24 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 SMART SM00983 141 207 4.1E-17 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 Gene3D G3DSA:2.60.120.320 119 213 3.7E-16 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 125 5.7E-18 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 SUPERFAMILY SSF63862 133 212 4.18E-10 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 151 206 1.8E-12 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS18165 010bb794bdc25649aacccf85fc6c5f9c 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 7 209 2.9E-50 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A21D_RS17315 17a2cff0640cd572bd290aae0c8534b7 380 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 30 356 3.2E-49 T 28-03-2018 IPR006427 Phage portal protein, HK97 A21D_RS17315 17a2cff0640cd572bd290aae0c8534b7 380 Pfam PF04860 Phage portal protein 38 350 4.9E-34 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A21D_RS00040 17a2cff0640cd572bd290aae0c8534b7 380 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 30 356 3.2E-49 T 28-03-2018 IPR006427 Phage portal protein, HK97 A21D_RS00040 17a2cff0640cd572bd290aae0c8534b7 380 Pfam PF04860 Phage portal protein 38 350 4.9E-34 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 312 8.7E-44 T 28-03-2018 IPR000477 Reverse transcriptase domain A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 SUPERFAMILY SSF56672 55 395 3.43E-54 T 28-03-2018 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 228 241 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 170 188 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 102 115 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 246 259 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 Gene3D G3DSA:3.30.70.270 141 313 2.8E-33 T 28-03-2018 A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 51 395 1.1E-127 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase A21D_RS12850 53c704212d3acfe47ec324a5f2670343 462 Pfam PF08388 Group II intron, maturase-specific domain 332 403 7.7E-14 T 28-03-2018 IPR013597 Group II intron, maturase-specific A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 312 8.7E-44 T 28-03-2018 IPR000477 Reverse transcriptase domain A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 SUPERFAMILY SSF56672 55 395 3.43E-54 T 28-03-2018 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 228 241 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 170 188 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 102 115 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 246 259 1.1E-7 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 Gene3D G3DSA:3.30.70.270 141 313 2.8E-33 T 28-03-2018 A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 51 395 1.1E-127 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase A21D_RS03000 53c704212d3acfe47ec324a5f2670343 462 Pfam PF08388 Group II intron, maturase-specific domain 332 403 7.7E-14 T 28-03-2018 IPR013597 Group II intron, maturase-specific A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Pfam PF04509 CheC-like family 142 178 7.8E-15 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Pfam PF04509 CheC-like family 46 82 3.8E-12 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 SUPERFAMILY SSF103039 41 228 2.18E-49 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 308 378 3.5E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Gene3D G3DSA:2.30.330.10 296 388 4.1E-29 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 SUPERFAMILY SSF101801 304 386 4.32E-25 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Gene3D G3DSA:3.40.1550.10 93 218 8.2E-35 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 Gene3D G3DSA:3.40.1550.10 3 92 2.4E-17 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 305 380 1.5E-31 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 PRINTS PR00956 Flagellar motor switch protein FliN signature 308 324 8.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 PRINTS PR00956 Flagellar motor switch protein FliN signature 341 354 8.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 PRINTS PR00956 Flagellar motor switch protein FliN signature 325 341 8.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A21D_RS17885 c5b80c22ba7045f86641aa919c1374e6 388 PRINTS PR00956 Flagellar motor switch protein FliN signature 354 369 8.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SUPERFAMILY SSF53098 3 184 7.99E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Gene3D G3DSA:3.40.50.300 737 908 5.9E-13 T 28-03-2018 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SUPERFAMILY SSF52540 674 688 8.47E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SUPERFAMILY SSF52540 721 892 8.47E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SUPERFAMILY SSF52540 416 485 8.47E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SUPERFAMILY SSF52540 272 326 8.47E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Pfam PF00270 DEAD/DEAH box helicase 262 330 2.7E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Gene3D G3DSA:3.30.420.10 2 154 2.3E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Pfam PF13307 Helicase C-terminal domain 748 912 5.7E-41 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Gene3D G3DSA:3.40.50.300 256 706 1.1E-28 T 28-03-2018 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 172 1.0E-33 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 3 917 4.9E-254 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SMART SM00479 3 170 2.0E-48 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Pfam PF00929 Exonuclease 5 161 6.6E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 Gene3D G3DSA:1.20.5.140 155 171 4.3E-6 T 28-03-2018 A21D_RS16730 d0681a90ce52bf41bcbd7477987d95bf 931 SMART SM00491 765 899 2.2E-38 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Pfam PF02817 e3 binding domain 115 148 7.9E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Pfam PF00364 Biotin-requiring enzyme 5 77 2.1E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 190 413 3.8E-80 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Gene3D G3DSA:4.10.320.10 107 167 2.1E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Gene3D G3DSA:2.40.50.100 6 65 4.1E-17 T 28-03-2018 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 SUPERFAMILY SSF51230 2 95 1.57E-26 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 SUPERFAMILY SSF52777 189 414 1.16E-82 T 28-03-2018 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 SUPERFAMILY SSF47005 108 152 7.19E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Gene3D G3DSA:3.30.559.10 172 419 6.2E-86 T 28-03-2018 A21D_RS16205 9d8883ceb858211c6a23c55dfb6cf5df 419 Gene3D G3DSA:3.90.1170.30 66 106 0.15 T 28-03-2018 A21D_RS11535 507afe2ca804cee144a97fd52da457d9 252 SMART SM00563 69 183 3.7E-41 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS11535 507afe2ca804cee144a97fd52da457d9 252 Pfam PF01553 Acyltransferase 56 180 1.6E-33 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS11535 507afe2ca804cee144a97fd52da457d9 252 SUPERFAMILY SSF69593 51 233 6.28E-47 T 28-03-2018 A21D_RS11535 507afe2ca804cee144a97fd52da457d9 252 Gene3D G3DSA:3.40.1130.10 18 251 7.9E-52 T 28-03-2018 A21D_RS11535 507afe2ca804cee144a97fd52da457d9 252 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 55 180 1.2E-38 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 SUPERFAMILY SSF82607 9 103 1.18E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 103 1.4E-30 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 PIRSF PIRSF004555 1 104 2.4E-38 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 Pfam PF02575 YbaB/EbfC DNA-binding family 9 99 9.8E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 Gene3D G3DSA:3.30.1310.10 1 104 1.9E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS06895 073876b5d327733d181e81e8349e29f2 104 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 97 22.813 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 SUPERFAMILY SSF52518 5 326 1.74E-117 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Pfam PF02780 Transketolase, C-terminal domain 550 658 8.7E-10 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Pfam PF02779 Transketolase, pyrimidine binding domain 355 526 2.0E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 SUPERFAMILY SSF52518 338 528 2.74E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 SMART SM00861 356 527 1.4E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Gene3D G3DSA:3.40.50.920 545 666 1.4E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 3.1E-151 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Gene3D G3DSA:3.40.50.970 1 364 4.2E-113 T 28-03-2018 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 Gene3D G3DSA:3.40.50.970 365 544 3.6E-45 T 28-03-2018 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 SUPERFAMILY SSF52922 536 667 1.57E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A21D_RS17165 cca1576749341ea07be8d27406c8dfe8 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 8 665 6.2E-298 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Gene3D G3DSA:3.30.450.20 38 180 1.2E-23 T 28-03-2018 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 331 383 2.6E-10 T 28-03-2018 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Pfam PF17203 Single cache domain 3 49 177 7.8E-19 T 28-03-2018 IPR033463 Single cache domain 3 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SUPERFAMILY SSF103190 45 176 3.18E-33 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Pfam PF13426 PAS domain 232 321 8.3E-7 T 28-03-2018 IPR000014 PAS domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SMART SM00091 221 287 8.8E-4 T 28-03-2018 IPR000014 PAS domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 531 1.6E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Gene3D G3DSA:3.30.565.10 396 536 5.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SUPERFAMILY SSF55785 225 318 7.85E-10 T 28-03-2018 IPR000014 PAS domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Gene3D G3DSA:1.10.287.130 334 380 4.7E-16 T 28-03-2018 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SMART SM00387 425 535 2.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SUPERFAMILY SSF55874 425 531 2.36E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 Gene3D G3DSA:3.30.450.20 214 333 3.4E-11 T 28-03-2018 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 SUPERFAMILY SSF55890 328 414 3.27E-14 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 513 6.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 494 6.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 532 6.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08210 3d2119d313c09ce6321db54b94e6fd68 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 480 6.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.7E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.7E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.7E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 Gene3D G3DSA:1.10.1660.10 58 202 7.7E-6 T 28-03-2018 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 Gene3D G3DSA:1.10.1660.10 1 57 2.0E-21 T 28-03-2018 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 SMART SM00422 2 71 6.0E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 SUPERFAMILY SSF46955 3 104 1.76E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS09355 c704a4482034db6a2e80b735cc18b9a3 249 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 Gene3D G3DSA:1.20.210.10 42 556 4.7E-186 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 500 1.2E-141 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 2.0E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 Gene3D G3DSA:1.10.287.70 567 634 1.4E-14 T 28-03-2018 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 SUPERFAMILY SSF81442 44 554 1.19E-173 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09795 a167b9a4fa3ea9115e06def6ce4a0b23 648 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 4 643 0.0 T 28-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 A21D_RS07585 435bd0af66aafb4e7a2fb7bcebbe47ef 180 SUPERFAMILY SSF46785 9 179 5.89E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07585 435bd0af66aafb4e7a2fb7bcebbe47ef 180 Gene3D G3DSA:1.10.10.10 3 96 3.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07585 435bd0af66aafb4e7a2fb7bcebbe47ef 180 Pfam PF03551 Transcriptional regulator PadR-like family 11 84 7.3E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal A21D_RS07585 435bd0af66aafb4e7a2fb7bcebbe47ef 180 Pfam PF10400 Virulence activator alpha C-term 98 179 3.8E-18 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal A21D_RS02170 54093359b96e26d3ceb15550dc557e37 239 Pfam PF13780 Domain of unknown function (DUF4176) 116 198 2.9E-16 T 28-03-2018 IPR025233 Protein of unknown function DUF4176 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Gene3D G3DSA:3.40.50.720 242 437 6.7E-54 T 28-03-2018 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Gene3D G3DSA:1.20.5.170 218 241 1.4E-8 T 28-03-2018 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 SUPERFAMILY SSF48179 218 310 4.59E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 PIRSF PIRSF000124 19 437 4.1E-60 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 20 424 2.7E-121 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 SMART SM00984 331 428 2.0E-22 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Gene3D G3DSA:3.40.50.720 11 216 2.6E-36 T 28-03-2018 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 SUPERFAMILY SSF51735 20 212 7.41E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 220 309 2.4E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 331 427 8.2E-21 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 SUPERFAMILY SSF52413 327 433 4.84E-22 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 20 198 3.2E-41 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS08625 4b62e2ef316dcdc281f62e6747610b92 439 PIRSF PIRSF500136 10 438 1.7E-136 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 SMART SM00862 152 228 8.0E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 SMART SM00448 3 113 6.5E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 6.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 Gene3D G3DSA:3.40.50.2300 2 131 1.2E-34 T 28-03-2018 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 Pfam PF00072 Response regulator receiver domain 5 113 3.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 SUPERFAMILY SSF52172 4 184 3.56E-37 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS19505 6da18006a6d7b7e924730e64b2e9cc00 233 Gene3D G3DSA:1.10.10.10 132 233 3.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18155 4ace1782fe89b7485e903b8f8812922c 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 2.1E-21 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS18155 4ace1782fe89b7485e903b8f8812922c 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.098 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS18155 4ace1782fe89b7485e903b8f8812922c 62 SUPERFAMILY SSF143800 1 60 3.53E-22 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18155 4ace1782fe89b7485e903b8f8812922c 62 Gene3D G3DSA:2.30.170.40 2 62 3.9E-18 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18155 4ace1782fe89b7485e903b8f8812922c 62 Pfam PF00830 Ribosomal L28 family 3 58 9.9E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Pfam PF03717 Penicillin-binding Protein dimerisation domain 157 323 1.3E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Gene3D G3DSA:3.30.1390.30 179 232 1.2E-21 T 28-03-2018 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 26 148 6.6E-28 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 SUPERFAMILY SSF56601 339 666 9.71E-77 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Pfam PF00905 Penicillin binding protein transpeptidase domain 359 663 2.7E-64 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Gene3D G3DSA:3.10.450.100 23 145 6.4E-33 T 28-03-2018 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 SUPERFAMILY SSF54427 28 148 2.02E-28 T 28-03-2018 IPR032710 NTF2-like domain A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Gene3D G3DSA:3.90.1310.10 233 337 9.1E-22 T 28-03-2018 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 SUPERFAMILY SSF56519 153 338 3.79E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS00950 8be3d9d4137451202d2c851e6a390317 670 Gene3D G3DSA:3.40.710.10 338 670 2.3E-67 T 28-03-2018 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 554 5.9E-11 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 PIRSF PIRSF004983 1 579 3.4E-195 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 176 1.5E-35 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Gene3D G3DSA:3.40.50.1220 210 370 1.5E-27 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 448 1.5E-146 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Gene3D G3DSA:3.40.50.970 371 575 4.7E-30 T 28-03-2018 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 SUPERFAMILY SSF52467 170 371 1.24E-9 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 SUPERFAMILY SSF52518 14 179 3.04E-36 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Pfam PF16582 Middle domain of thiamine pyrophosphate 223 405 3.6E-16 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 SUPERFAMILY SSF52518 382 577 5.68E-31 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Gene3D G3DSA:3.40.50.970 1 185 1.4E-53 T 28-03-2018 A21D_RS14075 0d9545c35d4fd8f0f61ab4b7041da827 582 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 572 34.771 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 189 318 9.4E-46 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 Gene3D G3DSA:3.30.1380.10 154 330 5.3E-37 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 SUPERFAMILY SSF55166 174 326 4.19E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 Gene3D G3DSA:1.10.101.10 34 125 1.7E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 Pfam PF01471 Putative peptidoglycan binding domain 60 113 5.2E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS07070 49e187b8a3b4f0e21e841a8f9526f7bc 338 SUPERFAMILY SSF47090 54 114 2.22E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 285 615 2.3E-123 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 165 248 1.4E-27 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 Pfam PF02378 Phosphotransferase system, EIIC 292 561 4.8E-18 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 130 1.1E-32 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 SUPERFAMILY SSF55804 1 145 3.01E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 167 256 5.7E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 SUPERFAMILY SSF52794 164 259 7.67E-32 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 Gene3D G3DSA:3.40.930.10 1 147 1.4E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 145 5.7E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 Gene3D G3DSA:3.40.50.2300 163 259 1.4E-34 T 28-03-2018 A21D_RS07900 acd5be79fcc210c7e2227f254aeb36f4 633 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SUPERFAMILY SSF75138 72 185 7.98E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Pfam PF03061 Thioesterase superfamily 359 421 7.9E-6 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Gene3D G3DSA:3.40.1390.20 70 190 2.4E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SUPERFAMILY SSF54631 182 310 7.07E-29 T 28-03-2018 A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Gene3D G3DSA:1.10.10.10 4 69 8.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Gene3D G3DSA:3.10.129.10 301 435 8.5E-19 T 28-03-2018 A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Pfam PF00571 CBS domain 222 245 1.7E-4 T 28-03-2018 IPR000644 CBS domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Pfam PF00571 CBS domain 253 307 8.2E-8 T 28-03-2018 IPR000644 CBS domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SUPERFAMILY SSF46785 4 54 1.67E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Gene3D G3DSA:3.10.580.10 191 300 5.7E-27 T 28-03-2018 A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Pfam PF07085 DRTGG domain 76 178 2.8E-29 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SMART SM00116 259 307 1.0E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SMART SM00116 200 248 8.6 T 28-03-2018 IPR000644 CBS domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 SUPERFAMILY SSF54637 302 423 1.87E-13 T 28-03-2018 IPR029069 HotDog domain A21D_RS14490 7f28ee9e0140c172d0334a69c05b3e29 435 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 58 1.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08285 084246421bdeea277bc283c57604c75a 631 Pfam PF08298 PrkA AAA domain 22 369 8.9E-149 T 28-03-2018 IPR013153 PrkA AAA domain A21D_RS08285 084246421bdeea277bc283c57604c75a 631 SMART SM00763 21 371 2.0E-199 T 28-03-2018 IPR013153 PrkA AAA domain A21D_RS08285 084246421bdeea277bc283c57604c75a 631 PIRSF PIRSF000549 1 631 9.2E-264 T 28-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 A21D_RS08285 084246421bdeea277bc283c57604c75a 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.4E-93 T 28-03-2018 IPR010650 PrkA C-terminal domain A21D_RS08285 084246421bdeea277bc283c57604c75a 631 SUPERFAMILY SSF52540 231 363 1.05E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08285 084246421bdeea277bc283c57604c75a 631 SUPERFAMILY SSF52540 405 444 1.05E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08285 084246421bdeea277bc283c57604c75a 631 SUPERFAMILY SSF52540 67 176 1.05E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08285 084246421bdeea277bc283c57604c75a 631 Gene3D G3DSA:3.40.50.300 7 352 7.8E-8 T 28-03-2018 A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 SUPERFAMILY SSF53955 46 254 1.77E-68 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 Gene3D G3DSA:3.40.710.10 252 658 6.1E-97 T 28-03-2018 A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 Gene3D G3DSA:1.10.3810.10 50 251 7.8E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 71 606 1.5E-164 T 28-03-2018 A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 Pfam PF00905 Penicillin binding protein transpeptidase domain 323 567 4.2E-28 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 SUPERFAMILY SSF56601 267 657 1.82E-103 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 SUPERFAMILY SSF56601 214 236 1.82E-103 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS04790 61350373af3d3a461b164d4caad2afa9 684 Pfam PF00912 Transglycosylase 57 232 6.3E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 Pfam PF00664 ABC transporter transmembrane region 18 282 1.1E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 SUPERFAMILY SSF52540 325 570 1.63E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 SUPERFAMILY SSF90123 3 311 2.09E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 Gene3D G3DSA:3.40.50.300 318 575 1.1E-70 T 28-03-2018 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 Gene3D G3DSA:1.20.1560.10 1 313 4.5E-66 T 28-03-2018 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 Pfam PF00005 ABC transporter 352 501 1.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13585 fd27004a0788defc51fd0f5cfface31f 578 SMART SM00382 361 545 7.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SUPERFAMILY SSF50249 183 263 1.22E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Gene3D G3DSA:2.40.50.140 271 364 1.0E-26 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Gene3D G3DSA:2.40.50.140 169 257 4.0E-28 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SUPERFAMILY SSF50249 11 107 1.42E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SMART SM00316 269 340 1.3E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SMART SM00316 184 254 1.3E-29 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SMART SM00316 13 82 1.9E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SMART SM00316 98 165 1.2E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 33 47 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 15 33 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 120 137 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 79 98 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 284 303 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 103 119 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 323 341 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 206 227 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 PRINTS PR00681 Ribosomal protein S1 signature 149 169 2.7E-56 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SUPERFAMILY SSF50249 85 169 1.29E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 SUPERFAMILY SSF50249 270 355 8.24E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Gene3D G3DSA:2.40.50.140 6 88 1.7E-14 T 28-03-2018 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Pfam PF00575 S1 RNA binding domain 13 81 3.5E-11 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Pfam PF00575 S1 RNA binding domain 184 254 6.3E-24 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Pfam PF00575 S1 RNA binding domain 270 340 1.1E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Pfam PF00575 S1 RNA binding domain 96 165 6.7E-11 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS16535 bddc10141f01d968eeaf71615fd6d8b4 378 Gene3D G3DSA:2.40.50.140 89 168 1.6E-10 T 28-03-2018 A21D_RS04830 62456866282654347c73e93d6f4ae5fc 154 PIRSF PIRSF038931 1 154 6.5E-55 T 28-03-2018 IPR014099 Spore coat protein GerQ A21D_RS04830 62456866282654347c73e93d6f4ae5fc 154 Pfam PF09671 Spore coat protein (Spore_GerQ) 64 138 3.5E-42 T 28-03-2018 IPR014099 Spore coat protein GerQ A21D_RS04830 62456866282654347c73e93d6f4ae5fc 154 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 61 142 4.2E-47 T 28-03-2018 IPR014099 Spore coat protein GerQ A21D_RS08630 68516a18784b2af53fa6f161533665b0 387 Gene3D G3DSA:3.90.1150.10 250 387 8.6E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS08630 68516a18784b2af53fa6f161533665b0 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 378 3.7E-128 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS08630 68516a18784b2af53fa6f161533665b0 387 PIRSF PIRSF000390 3 385 2.0E-109 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS08630 68516a18784b2af53fa6f161533665b0 387 Gene3D G3DSA:3.40.640.10 8 249 1.7E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS08630 68516a18784b2af53fa6f161533665b0 387 SUPERFAMILY SSF53383 7 382 4.35E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:2.30.30.40 615 668 1.1E-21 T 28-03-2018 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SUPERFAMILY SSF55874 349 533 8.12E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Pfam PF01584 CheW-like domain 540 668 1.1E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:3.30.565.10 349 536 1.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:2.40.50.180 558 614 1.3E-10 T 28-03-2018 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SUPERFAMILY SSF55052 167 249 1.02E-22 T 28-03-2018 IPR015162 CheY binding A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Pfam PF01627 Hpt domain 6 105 1.6E-19 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SUPERFAMILY SSF47384 288 348 8.63E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SUPERFAMILY SSF47226 6 121 6.15E-32 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SMART SM00387 392 535 5.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 288 346 1.9E-11 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 513 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 451 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 532 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SMART SM00260 527 668 1.6E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Pfam PF07194 P2 response regulator binding domain 171 248 5.7E-25 T 28-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 534 4.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SMART SM01231 287 347 9.2E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:3.30.70.1110 169 248 6.8E-24 T 28-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SMART SM00073 3 100 1.5E-34 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 SUPERFAMILY SSF50341 534 668 1.27E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:1.20.120.160 2 143 1.5E-34 T 28-03-2018 A21D_RS17830 86d2bbbc637e925cbbe6e8657575909d 669 Gene3D G3DSA:1.10.287.560 287 348 2.3E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A21D_RS09135 4836204685e0392457148ac70453e2bb 432 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 9 411 8.8E-131 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A21D_RS09135 4836204685e0392457148ac70453e2bb 432 Pfam PF05525 Branched-chain amino acid transport protein 2 425 2.6E-148 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.1260 327 608 1.5E-17 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.1260 729 899 7.0E-17 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:3.60.21.10 1532 1790 3.1E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.1260 164 276 1.4E-8 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 SUPERFAMILY SSF56300 1533 1738 9.49E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 SUPERFAMILY SSF74853 143 227 4.45E-6 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 SUPERFAMILY SSF74853 469 549 5.89E-9 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 SUPERFAMILY SSF74853 758 859 4.84E-5 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.10 952 1053 2.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.1310 1312 1490 2.1E-6 T 28-03-2018 A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Gene3D G3DSA:2.60.40.10 74 163 1.2E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Pfam PF00932 Lamin Tail Domain 761 851 7.9E-11 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS12350 024cc14d58eef176ad04995385acc978 2018 Pfam PF00932 Lamin Tail Domain 471 601 2.9E-10 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS09730 b2e405dfbabe3ceb5bb0f7f01f61831b 165 SUPERFAMILY SSF55729 3 154 3.99E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS09730 b2e405dfbabe3ceb5bb0f7f01f61831b 165 Gene3D G3DSA:3.40.630.30 2 164 2.5E-25 T 28-03-2018 A21D_RS09730 b2e405dfbabe3ceb5bb0f7f01f61831b 165 Pfam PF13508 Acetyltransferase (GNAT) domain 53 145 2.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 Pfam PF02547 Queuosine biosynthesis protein 4 341 1.2E-142 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 7.3E-144 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 45.843 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 SUPERFAMILY SSF111337 1 341 1.57E-139 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 Gene3D G3DSA:3.40.1780.10 1 139 8.8E-43 T 28-03-2018 A21D_RS15280 5b6fd13c2744d725b999472eca79beee 343 Gene3D G3DSA:3.40.1780.10 173 342 1.0E-68 T 28-03-2018 A21D_RS10385 b5c2d11299678e347690d7901d269738 500 SUPERFAMILY SSF56399 320 496 1.7E-37 T 28-03-2018 A21D_RS10385 b5c2d11299678e347690d7901d269738 500 Pfam PF04233 Phage Mu protein F like protein 155 273 2.7E-20 T 28-03-2018 IPR006528 Phage head morphogenesis domain A21D_RS10385 b5c2d11299678e347690d7901d269738 500 Pfam PF03496 ADP-ribosyltransferase exoenzyme 326 482 2.1E-32 T 28-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 A21D_RS10385 b5c2d11299678e347690d7901d269738 500 Gene3D G3DSA:3.90.176.10 313 497 4.9E-42 T 28-03-2018 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 331 9.0E-58 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 4.1E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 4.1E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 312 323 4.1E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 232 242 4.1E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 4.1E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 SUPERFAMILY SSF53671 8 334 3.14E-103 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 334 83.046 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 298 321 2.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 278 2.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 2.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 332 5.3E-132 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Gene3D G3DSA:3.40.50.1370 308 337 1.0E-5 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 152 1.5E-47 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Gene3D G3DSA:3.40.50.1370 2 151 7.9E-56 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS07950 43ffb1d758c9a8365b2cdfe93c7b5958 338 Gene3D G3DSA:3.40.50.1370 152 307 1.8E-56 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 Gene3D G3DSA:3.40.50.2300 1 146 3.0E-33 T 28-03-2018 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 SMART SM00448 2 115 1.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 8.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 SMART SM00421 137 194 3.0E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 SUPERFAMILY SSF46894 123 200 6.8E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 SUPERFAMILY SSF52172 1 128 7.4E-30 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 Gene3D G3DSA:1.10.10.10 147 200 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09055 1c8fb9bd01f852dcc4eb71e585beb162 200 Pfam PF00072 Response regulator receiver domain 4 116 4.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 Pfam PF02049 Flagellar hook-basal body complex protein FliE 18 102 3.1E-27 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 87 100 2.2E-14 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 2.2E-14 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 66 82 2.2E-14 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 102 17.855 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 Gene3D G3DSA:3.30.70.890 13 100 8.4E-5 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS17950 cb64abc0783a09e5a78c68ff648352ea 102 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 2 102 1.4E-23 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 2.8E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 2.8E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 2.8E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 2.8E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 Gene3D G3DSA:3.40.50.620 1 188 5.9E-72 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 Pfam PF00579 tRNA synthetases class I (W and Y) 3 282 5.6E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 41.331 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 325 1.8E-114 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 Gene3D G3DSA:1.10.240.10 189 308 1.3E-32 T 28-03-2018 A21D_RS13435 5e5ae201060c693c6b7f31a87e5698c0 332 SUPERFAMILY SSF52374 2 325 8.44E-95 T 28-03-2018 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 9.0E-32 T 28-03-2018 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 1.9E-59 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 Pfam PF10369 Small subunit of acetolactate synthase 85 158 9.9E-25 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 Gene3D G3DSA:3.30.70.1150 89 161 1.2E-26 T 28-03-2018 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 SUPERFAMILY SSF55021 2 79 5.42E-19 T 28-03-2018 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 Pfam PF01842 ACT domain 5 68 5.7E-14 T 28-03-2018 IPR002912 ACT domain A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 Gene3D G3DSA:3.30.70.260 2 88 4.6E-24 T 28-03-2018 A21D_RS01445 85a349b7963147d301509408cd2c96d7 172 SUPERFAMILY SSF55021 81 161 7.33E-25 T 28-03-2018 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 Gene3D G3DSA:3.40.50.1980 205 323 1.9E-31 T 28-03-2018 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 Gene3D G3DSA:3.40.50.1980 22 204 5.3E-53 T 28-03-2018 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 PRINTS PR00691 Adhesin B signature 77 96 3.9E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 PRINTS PR00691 Adhesin B signature 58 76 3.9E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 PRINTS PR00691 Adhesin B signature 303 321 3.9E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 322 5.8E-68 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A21D_RS00295 e90cbd00ffc1626e3786be1ae80e24f8 325 SUPERFAMILY SSF53807 33 321 2.7E-74 T 28-03-2018 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 253 1.4E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 SUPERFAMILY SSF88659 108 181 1.48E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 PRINTS PR00046 Major sigma-70 factor signature 207 219 2.2E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 PRINTS PR00046 Major sigma-70 factor signature 239 250 2.2E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 PRINTS PR00046 Major sigma-70 factor signature 224 239 2.2E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 PRINTS PR00046 Major sigma-70 factor signature 59 72 2.2E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 SUPERFAMILY SSF88946 21 104 8.11E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 254 1.0E-88 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 224 250 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Pfam PF04545 Sigma-70, region 4 206 252 2.5E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 1 255 2.2E-133 T 28-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Pfam PF04539 Sigma-70 region 3 114 188 6.0E-13 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Pfam PF04542 Sigma-70 region 2 35 104 1.4E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 SUPERFAMILY SSF88659 182 256 6.54E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Gene3D G3DSA:1.10.10.10 184 261 4.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Gene3D G3DSA:1.10.1740.10 19 102 3.1E-21 T 28-03-2018 A21D_RS10060 0fab67b4df093b5cffe26b23f6542163 263 Gene3D G3DSA:1.10.10.10 105 156 4.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00870 75efb0f3931b588f2018318d414765ec 135 Gene3D G3DSA:1.10.10.60 25 134 9.7E-5 T 28-03-2018 A21D_RS00870 75efb0f3931b588f2018318d414765ec 135 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 2 134 1.1E-49 T 28-03-2018 IPR022258 Flagellar operon protein YvyF A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF51569 527 838 1.23E-79 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF51230 1069 1147 2.49E-21 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.10.600.10 466 528 3.0E-17 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF00682 HMGL-like 535 805 1.0E-21 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF00364 Biotin-requiring enzyme 1080 1146 1.3E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF56059 89 330 3.54E-68 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF51246 342 461 1.41E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 9 1147 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF02436 Conserved carboxylase domain 830 1030 6.6E-75 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF52440 4 118 2.88E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF02785 Biotin carboxylase C-terminal domain 347 454 4.2E-30 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 PIRSF PIRSF001594 2 1147 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.40.50.20 6 129 1.5E-49 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:2.40.50.100 1076 1147 4.6E-18 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SMART SM00878 347 454 5.3E-49 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:1.10.10.60 946 991 3.1E-20 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.20.20.70 529 826 5.7E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.30.470.20 216 456 1.3E-90 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.10.600.10 992 1063 1.6E-23 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 SUPERFAMILY SSF89000 835 1012 1.02E-56 T 28-03-2018 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 121 328 3.6E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Gene3D G3DSA:3.30.1490.20 130 215 2.7E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS18565 1ffa98ebd7db2a638ce43fd7b75c3b1a 1147 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 1.8E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS09315 27ad38f5115cfc10319fa4a8b4efb6a7 305 Gene3D G3DSA:3.20.20.140 10 300 2.0E-50 T 28-03-2018 A21D_RS09315 27ad38f5115cfc10319fa4a8b4efb6a7 305 Pfam PF02126 Phosphotriesterase family 9 298 6.3E-71 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 A21D_RS09315 27ad38f5115cfc10319fa4a8b4efb6a7 305 SUPERFAMILY SSF51556 12 299 6.81E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS09315 27ad38f5115cfc10319fa4a8b4efb6a7 305 PIRSF PIRSF016839 1 304 1.3E-83 T 28-03-2018 A21D_RS01435 195259ab842b844c955af92b828525bf 516 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 42.323 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 498 7.8E-220 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 SUPERFAMILY SSF110921 396 500 1.7E-17 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 SMART SM00917 368 501 1.3E-32 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 500 6.2E-33 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 Pfam PF00682 HMGL-like 4 272 1.7E-96 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A21D_RS01435 195259ab842b844c955af92b828525bf 516 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A21D_RS01435 195259ab842b844c955af92b828525bf 516 SUPERFAMILY SSF51569 2 290 1.39E-99 T 28-03-2018 A21D_RS01435 195259ab842b844c955af92b828525bf 516 Gene3D G3DSA:3.20.20.70 2 329 1.0E-112 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Pfam PF05192 MutS domain III 261 550 8.4E-43 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Gene3D G3DSA:1.10.1420.10 398 526 1.6E-31 T 28-03-2018 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Gene3D G3DSA:3.40.50.300 558 829 2.0E-49 T 28-03-2018 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SMART SM00533 273 581 2.9E-112 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 PIRSF PIRSF037677 160 838 6.0E-137 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 PIRSF PIRSF037677 1 176 6.4E-33 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 853 25.421 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 679 695 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SUPERFAMILY SSF48334 256 557 1.23E-90 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Pfam PF01624 MutS domain I 5 116 5.7E-46 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Pfam PF05188 MutS domain II 125 241 1.4E-9 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Pfam PF05190 MutS family domain IV 418 509 1.7E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SUPERFAMILY SSF55271 2 112 6.02E-44 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SMART SM00534 598 785 1.0E-116 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SUPERFAMILY SSF52540 558 789 1.42E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Pfam PF00488 MutS domain V 602 788 4.9E-85 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Gene3D G3DSA:3.30.420.110 129 251 4.4E-15 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 5 859 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Gene3D G3DSA:1.10.1420.10 252 397 1.3E-34 T 28-03-2018 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 SUPERFAMILY SSF53150 114 269 9.55E-29 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A21D_RS17540 1d0202cf74532d19c630a17a6d6682e1 863 Gene3D G3DSA:3.40.1170.10 1 128 1.1E-49 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 SUPERFAMILY SSF47203 229 378 6.88E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Gene3D G3DSA:2.40.110.10 121 217 7.6E-37 T 28-03-2018 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 6.7E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Gene3D G3DSA:1.20.140.10 218 379 4.1E-61 T 28-03-2018 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.6E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 PIRSF PIRSF016578 4 377 1.8E-24 T 28-03-2018 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 3.4E-52 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 SUPERFAMILY SSF56645 1 243 9.82E-83 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS17035 d45b490aee06de25493b58804917f3fa 380 Gene3D G3DSA:1.10.540.10 1 120 3.4E-36 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS10785 11800142d05416edccfafd4b96bfe0b1 193 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 4 179 1.1E-60 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A21D_RS10785 11800142d05416edccfafd4b96bfe0b1 193 SUPERFAMILY SSF102405 3 179 4.27E-61 T 28-03-2018 A21D_RS10785 11800142d05416edccfafd4b96bfe0b1 193 Pfam PF03641 Possible lysine decarboxylase 46 175 1.9E-43 T 28-03-2018 IPR031100 LOG family A21D_RS10785 11800142d05416edccfafd4b96bfe0b1 193 Gene3D G3DSA:3.40.50.450 1 191 9.5E-60 T 28-03-2018 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Gene3D G3DSA:3.40.50.2300 392 477 2.9E-8 T 28-03-2018 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Gene3D G3DSA:3.40.930.10 527 668 1.3E-12 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Pfam PF00874 PRD domain 294 381 4.5E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 SUPERFAMILY SSF63520 279 385 2.49E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 SUPERFAMILY SSF55804 529 667 1.05E-14 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Gene3D G3DSA:1.10.1790.10 281 386 5.7E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 531 667 1.1E-9 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS01925 96c3cb31376d3537bcd60a199c9af4d8 684 Gene3D G3DSA:1.10.10.10 67 148 4.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19040 d44ad538d83fbf1cb97561078d579f30 148 Pfam PF16895 Domain of unknown function (DUF5085) 10 144 4.2E-12 T 28-03-2018 IPR031664 Protein of unknown function DUF5085 A21D_RS19040 d44ad538d83fbf1cb97561078d579f30 148 Gene3D G3DSA:3.20.80.10 2 70 0.032 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain A21D_RS13210 9ff7720943afdfe630b3f4f78bb7a0ef 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 16 378 1.9E-101 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS13210 9ff7720943afdfe630b3f4f78bb7a0ef 387 SUPERFAMILY SSF56796 9 384 4.19E-103 T 28-03-2018 A21D_RS13210 9ff7720943afdfe630b3f4f78bb7a0ef 387 Gene3D G3DSA:1.20.1090.10 188 387 3.4E-50 T 28-03-2018 A21D_RS13210 9ff7720943afdfe630b3f4f78bb7a0ef 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 177 205 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS13210 9ff7720943afdfe630b3f4f78bb7a0ef 387 Gene3D G3DSA:3.40.50.1970 14 187 5.7E-43 T 28-03-2018 A21D_RS13145 0376d9acbf60e7bceccecd82c82df2fd 308 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 11 21 - T 28-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 A21D_RS13145 0376d9acbf60e7bceccecd82c82df2fd 308 Gene3D G3DSA:3.90.245.10 1 308 2.4E-97 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS13145 0376d9acbf60e7bceccecd82c82df2fd 308 SUPERFAMILY SSF53590 6 307 6.28E-96 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS13145 0376d9acbf60e7bceccecd82c82df2fd 308 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 297 2.3E-83 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 Gene3D G3DSA:3.40.50.720 1 184 1.9E-58 T 28-03-2018 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 SUPERFAMILY SSF48179 185 282 3.66E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 SUPERFAMILY SSF51735 2 185 1.13E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 2.1E-64 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 Gene3D G3DSA:1.10.1040.10 185 283 5.6E-35 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.0E-36 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS04725 ecb95db66377ff51cb0fd9c7624d18a6 283 PIRSF PIRSF000105 1 283 2.3E-91 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 5 234 2.8E-128 T 28-03-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 SUPERFAMILY SSF53335 3 234 3.35E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 234 37.978 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 142 156 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 10 234 6.1E-87 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 Pfam PF01209 ubiE/COQ5 methyltransferase family 5 234 5.9E-100 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 21 36 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A21D_RS16595 a24e33592d19303935481f268bb8fb1d 238 Gene3D G3DSA:3.40.50.150 2 235 2.3E-46 T 28-03-2018 A21D_RS15960 a1f987560a77a48ad92afda8f60b5d65 111 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 1.3E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 7.7E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 SUPERFAMILY SSF46609 2 92 1.96E-38 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PIRSF PIRSF000349 1 203 2.1E-87 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 1.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 1.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.1E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 SUPERFAMILY SSF54719 90 201 4.45E-48 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 Gene3D G3DSA:1.10.287.990 21 91 6.9E-32 T 28-03-2018 A21D_RS15850 ab6a93c3e5c9044748a285c4e2cdf67a 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 1.5E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 30 237 3.5E-88 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 Gene3D G3DSA:3.40.50.620 16 246 4.3E-47 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 SUPERFAMILY SSF52402 26 200 8.37E-51 T 28-03-2018 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 43 213 3.5E-53 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 PIRSF PIRSF000857 4 243 3.3E-90 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 238 39.684 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A21D_RS07445 feb258ab03de5648776f95558fadb8e9 246 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 48 236 6.3E-74 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 A21D_RS09050 17bb0f16428f0a72f9167697507b313f 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 367 1.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09050 17bb0f16428f0a72f9167697507b313f 380 SMART SM00387 281 370 0.0027 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09050 17bb0f16428f0a72f9167697507b313f 380 Pfam PF07730 Histidine kinase 182 248 3.5E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A21D_RS09050 17bb0f16428f0a72f9167697507b313f 380 SUPERFAMILY SSF55874 251 367 3.14E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09050 17bb0f16428f0a72f9167697507b313f 380 Gene3D G3DSA:3.30.565.10 235 376 2.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Gene3D G3DSA:1.10.150.280 797 863 2.1E-6 T 28-03-2018 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Pfam PF01336 OB-fold nucleic acid binding domain 965 1024 8.5E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 284 705 1.5E-164 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 SUPERFAMILY SSF89550 10 252 4.71E-7 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 SMART SM00481 4 71 1.0E-19 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Pfam PF02811 PHP domain 5 162 3.1E-23 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Gene3D G3DSA:3.20.20.140 1 248 2.9E-27 T 28-03-2018 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 SUPERFAMILY SSF89550 10 71 8.24E-8 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 993 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Gene3D G3DSA:2.40.50.140 952 1033 1.4E-10 T 28-03-2018 A21D_RS14525 32548f682e761b76fb2a224de8c7dd86 1121 Pfam PF14579 Helix-hairpin-helix motif 780 866 8.6E-22 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Pfam PF00679 Elongation factor G C-terminus 403 490 2.7E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Pfam PF03144 Elongation factor Tu domain 2 209 279 1.1E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 178 1.8E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 SUPERFAMILY SSF50447 170 292 2.02E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 1.3E-51 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 SUPERFAMILY SSF54980 403 498 4.65E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Gene3D G3DSA:3.30.70.870 292 371 1.9E-28 T 28-03-2018 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Gene3D G3DSA:3.40.50.300 4 189 3.9E-37 T 28-03-2018 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 SUPERFAMILY SSF54980 296 374 1.08E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Hamap MF_00071 Elongation factor 4 [lepA]. 1 602 306.655 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Gene3D G3DSA:3.30.70.240 394 554 9.5E-31 T 28-03-2018 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Gene3D G3DSA:2.40.30.10 192 291 5.7E-27 T 28-03-2018 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 Pfam PF00009 Elongation factor Tu GTP binding domain 7 185 1.2E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 SUPERFAMILY SSF52540 6 209 2.38E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 TIGRFAM TIGR01393 lepA: elongation factor 4 7 600 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 A21D_RS15620 21fead06675a09df08ffd053e23c3863 602 SMART SM00838 405 490 9.3E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Hamap MF_00246 Galactokinase [galK]. 23 385 44.678 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00959 Mevalonate kinase family signature 161 180 3.1E-41 T 28-03-2018 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00959 Mevalonate kinase family signature 332 349 3.1E-41 T 28-03-2018 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00959 Mevalonate kinase family signature 118 140 3.1E-41 T 28-03-2018 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00959 Mevalonate kinase family signature 23 47 3.1E-41 T 28-03-2018 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Pfam PF00288 GHMP kinases N terminal domain 113 180 2.8E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Gene3D G3DSA:3.30.230.10 1 206 1.5E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 ProSitePatterns PS00106 Galactokinase signature. 25 36 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Pfam PF08544 GHMP kinases C terminal 286 364 8.1E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Pfam PF10509 Galactokinase galactose-binding signature 7 53 1.3E-19 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PIRSF PIRSF000530 1 388 1.0E-116 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 SUPERFAMILY SSF54211 2 201 8.35E-56 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 TIGRFAM TIGR00131 gal_kin: galactokinase 3 385 1.4E-115 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00473 Galactokinase signature 90 101 1.3E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00473 Galactokinase signature 268 282 1.3E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00473 Galactokinase signature 25 43 1.3E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 PRINTS PR00473 Galactokinase signature 111 129 1.3E-27 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 SUPERFAMILY SSF55060 204 381 9.21E-52 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS04140 57b3f9e127ad385dcc81ab8849b3465a 392 Gene3D G3DSA:3.30.70.890 207 376 4.2E-51 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 457 1.1E-229 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 SUPERFAMILY SSF48557 3 458 3.61E-148 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Pfam PF10415 Fumarase C C-terminus 406 458 1.4E-23 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 5.7E-5 T 28-03-2018 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 5.7E-5 T 28-03-2018 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Gene3D G3DSA:1.20.200.10 136 412 1.3E-86 T 28-03-2018 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Gene3D G3DSA:1.10.40.30 413 460 1.0E-24 T 28-03-2018 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Gene3D G3DSA:1.10.275.10 1 135 1.3E-58 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Pfam PF00206 Lyase 11 340 1.4E-115 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 86.6 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 1.1E-33 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.1E-33 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.1E-33 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS12995 b423197e5bb050edc054d4892851ae04 461 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.1E-33 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 Gene3D G3DSA:3.30.70.940 2 117 1.1E-44 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 SMART SM00739 123 150 1.8E-4 T 28-03-2018 IPR005824 KOW A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 Pfam PF02357 Transcription termination factor nusG 3 109 9.8E-29 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 Gene3D G3DSA:2.30.30.30 118 177 3.1E-22 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.332 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 Pfam PF00467 KOW motif 128 158 6.5E-7 T 28-03-2018 IPR005824 KOW A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 3.2E-67 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 SUPERFAMILY SSF50104 121 177 2.56E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.9E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.9E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.9E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 SUPERFAMILY SSF82679 2 114 2.62E-40 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A21D_RS06445 a9ddc19bb868c2dd347ab6800c9a8056 178 SMART SM00738 2 113 9.2E-54 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 SUPERFAMILY SSF52821 369 470 9.04E-30 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 SMART SM00849 12 195 4.8E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 SUPERFAMILY SSF56281 12 257 4.76E-51 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 Gene3D G3DSA:3.60.15.10 1 261 2.8E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 Gene3D G3DSA:3.40.250.10 357 474 1.7E-27 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 Gene3D G3DSA:3.40.250.10 262 343 3.8E-8 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 SMART SM00450 372 466 1.8E-26 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 Pfam PF00581 Rhodanese-like domain 374 462 1.1E-14 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 Pfam PF00753 Metallo-beta-lactamase superfamily 15 163 4.4E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07425 f250d70f6a9f7661a5cee44bbdfca6a9 475 SUPERFAMILY SSF52821 235 347 2.62E-11 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 9.4E-21 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Pfam PF01842 ACT domain 350 413 2.2E-9 T 28-03-2018 IPR002912 ACT domain A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Pfam PF00742 Homoserine dehydrogenase 138 316 6.6E-63 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Gene3D G3DSA:3.30.70.260 347 426 8.2E-13 T 28-03-2018 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Gene3D G3DSA:3.30.360.10 159 299 2.7E-52 T 28-03-2018 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 Gene3D G3DSA:3.40.50.720 1 158 1.6E-31 T 28-03-2018 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 SUPERFAMILY SSF55021 349 422 1.83E-9 T 28-03-2018 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 SUPERFAMILY SSF51735 3 159 3.65E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 SUPERFAMILY SSF55347 138 303 2.09E-51 T 28-03-2018 A21D_RS03650 5885d7508096ecf55e4cc8199e0a6283 443 PIRSF PIRSF000098 2 430 4.7E-163 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A21D_RS01630 c3d7aa851accf9445b407076060de948 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 227 4.3E-85 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A21D_RS01630 c3d7aa851accf9445b407076060de948 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 228 334 1.7E-35 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A21D_RS01630 c3d7aa851accf9445b407076060de948 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 327 3.3E-108 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A21D_RS01630 c3d7aa851accf9445b407076060de948 339 PIRSF PIRSF000267 1 339 8.7E-120 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 PIRSF PIRSF002939 2 209 5.7E-104 T 28-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 SUPERFAMILY SSF88659 116 203 1.96E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 200 1.4E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 Gene3D G3DSA:1.10.10.10 96 209 1.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 Pfam PF04542 Sigma-70 region 2 29 98 1.6E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 53 66 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 SUPERFAMILY SSF88946 11 98 3.53E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 SMART SM00421 153 205 0.0035 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 Pfam PF08281 Sigma-70, region 4 155 198 3.7E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 7 202 5.2E-108 T 28-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS06460 bb91028a9ede54aff154e3dd93304879 209 Gene3D G3DSA:1.10.1740.10 5 95 4.1E-19 T 28-03-2018 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 Gene3D G3DSA:3.90.1150.10 326 447 8.7E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 SUPERFAMILY SSF53383 10 442 1.86E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 443 52.998 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 Gene3D G3DSA:3.40.640.10 184 325 3.6E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 Pfam PF00202 Aminotransferase class-III 27 440 4.5E-114 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 440 1.0E-167 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 Gene3D G3DSA:3.90.1150.10 1 183 4.7E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS05045 beac0941a3f2fcb656b2e250e9128ba1 448 PIRSF PIRSF000521 27 443 1.2E-27 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS08195 ea61ec5113cd43af73550e4fab21541a 388 Pfam PF01963 TraB family 7 227 1.0E-35 T 28-03-2018 IPR002816 Pheromone shutdown, TraB A21D_RS08195 ea61ec5113cd43af73550e4fab21541a 388 TIGRFAM TIGR00261 traB: TraB family protein 11 384 4.3E-113 T 28-03-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 SUPERFAMILY SSF51735 3 237 3.66E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 237 5.1E-47 T 28-03-2018 A21D_RS17605 e4c4ed4d90a84e6a8efa673ddf0af2bc 237 Gene3D G3DSA:3.40.50.720 2 237 1.9E-53 T 28-03-2018 A21D_RS16175 fafb91d512686e84ab947e00b38da599 308 Gene3D G3DSA:3.40.50.10750 120 273 5.3E-40 T 28-03-2018 A21D_RS16175 fafb91d512686e84ab947e00b38da599 308 PIRSF PIRSF000428 2 305 2.8E-85 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS16175 fafb91d512686e84ab947e00b38da599 308 SUPERFAMILY SSF53659 10 301 6.58E-60 T 28-03-2018 A21D_RS16175 fafb91d512686e84ab947e00b38da599 308 Pfam PF01515 Phosphate acetyl/butaryl transferase 6 73 4.0E-6 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS16175 fafb91d512686e84ab947e00b38da599 308 Pfam PF01515 Phosphate acetyl/butaryl transferase 82 296 3.3E-47 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS17795 8a0b22f4128dd8b3ef92f5a4fff8f164 143 Gene3D G3DSA:1.10.10.60 49 132 7.9E-6 T 28-03-2018 A21D_RS17795 8a0b22f4128dd8b3ef92f5a4fff8f164 143 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 2 135 6.0E-16 T 28-03-2018 A21D_RS14305 ae9e667a3f6e7cf93e2888f37da7423f 200 Gene3D G3DSA:3.30.1940.10 23 89 9.8E-19 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 A21D_RS14305 ae9e667a3f6e7cf93e2888f37da7423f 200 Pfam PF01588 Putative tRNA binding domain 95 196 4.6E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A21D_RS14305 ae9e667a3f6e7cf93e2888f37da7423f 200 SUPERFAMILY SSF50249 90 198 6.61E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS14305 ae9e667a3f6e7cf93e2888f37da7423f 200 Pfam PF14794 Domain of unknown function (DUF4479) 23 90 9.8E-17 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 A21D_RS14305 ae9e667a3f6e7cf93e2888f37da7423f 200 Gene3D G3DSA:2.40.50.140 90 199 9.6E-41 T 28-03-2018 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 Pfam PF00107 Zinc-binding dehydrogenase 174 297 1.1E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 SMART SM00829 7 335 7.0E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 Gene3D G3DSA:3.90.180.10 1 165 6.4E-51 T 28-03-2018 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 SUPERFAMILY SSF51735 137 305 5.19E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS14890 a5482746f0b087ba0576016e99871879 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 6.5E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A21D_RS14890 a5482746f0b087ba0576016e99871879 340 SUPERFAMILY SSF50129 1 171 2.13E-46 T 28-03-2018 IPR011032 GroES-like A21D_RS14890 a5482746f0b087ba0576016e99871879 340 Gene3D G3DSA:3.40.50.720 166 285 5.8E-25 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 Pfam PF00702 haloacid dehalogenase-like hydrolase 320 534 1.2E-40 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF81665 75 127 4.84E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF81665 224 318 4.84E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF81665 569 595 4.84E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 445 456 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 555 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 467 477 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 173 187 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 520 539 9.7E-29 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF56784 417 619 2.52E-56 T 28-03-2018 IPR023214 HAD-like domain A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF56784 323 342 2.52E-56 T 28-03-2018 IPR023214 HAD-like domain A21D_RS11560 936972f45b2b3c483366818d16a46269 624 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 96 596 2.0E-86 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 73 622 3.7E-185 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 Pfam PF00122 E1-E2 ATPase 123 303 9.5E-49 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 SUPERFAMILY SSF81653 126 223 1.28E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00941 Cadmium-transporting ATPase signature 108 128 3.8E-10 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00941 Cadmium-transporting ATPase signature 128 144 3.8E-10 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00941 Cadmium-transporting ATPase signature 189 205 3.8E-10 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00941 Cadmium-transporting ATPase signature 208 222 3.8E-10 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 PRINTS PR00941 Cadmium-transporting ATPase signature 53 65 3.8E-10 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 Gene3D G3DSA:3.40.50.1000 446 586 3.0E-43 T 28-03-2018 IPR023214 HAD-like domain A21D_RS11560 936972f45b2b3c483366818d16a46269 624 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 73 411 5.1E-96 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 Gene3D G3DSA:3.40.1110.10 342 445 1.6E-23 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 Gene3D G3DSA:1.20.1110.10 35 341 3.3E-33 T 28-03-2018 A21D_RS11560 936972f45b2b3c483366818d16a46269 624 ProSitePatterns PS01229 Hypothetical cof family signature 2. 520 542 - T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF81653 196 293 2.75E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Gene3D G3DSA:1.20.1110.10 138 412 6.2E-43 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Pfam PF00403 Heavy-metal-associated domain 7 52 2.0E-9 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 396 402 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Pfam PF00702 haloacid dehalogenase-like hydrolase 390 607 4.2E-45 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Gene3D G3DSA:3.30.70.100 3 66 3.4E-12 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 143 696 1.5E-189 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 124 136 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 107 124 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 178 198 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 259 275 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 278 292 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 19 40 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 198 214 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00941 Cadmium-transporting ATPase signature 41 64 1.6E-60 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Gene3D G3DSA:3.40.1110.10 413 519 1.6E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 166 677 7.2E-88 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 125 696 2.9E-126 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF56784 392 412 1.47E-55 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF56784 451 694 1.47E-55 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF81665 145 197 2.22E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF81665 294 388 2.22E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF81665 634 689 2.22E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Pfam PF00122 E1-E2 ATPase 195 374 1.6E-55 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 144 479 1.0E-99 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 SUPERFAMILY SSF55008 5 57 5.5E-9 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 518 529 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 243 257 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 612 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 629 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 394 408 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 550 4.5E-26 T 28-03-2018 A21D_RS03975 013e1c59b851fb02eaf0f3f59072ca40 703 Gene3D G3DSA:3.40.50.1000 520 660 5.0E-37 T 28-03-2018 IPR023214 HAD-like domain A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 SUPERFAMILY SSF54862 3 70 9.87E-10 T 28-03-2018 A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 2.3E-16 T 28-03-2018 A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 1.4E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 1.4E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 1.4E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A21D_RS16460 e9d4e48dc61795ddb0453567e50a2403 74 Gene3D G3DSA:3.30.70.20 3 72 2.4E-6 T 28-03-2018 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Pfam PF00549 CoA-ligase 262 381 3.7E-25 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Gene3D G3DSA:3.30.470.20 97 239 1.4E-54 T 28-03-2018 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.563 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.7E-164 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 SUPERFAMILY SSF56059 1 238 9.3E-84 T 28-03-2018 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Gene3D G3DSA:3.30.1490.20 21 96 2.1E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Pfam PF08442 ATP-grasp domain 2 202 5.4E-81 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 Gene3D G3DSA:3.40.50.261 240 385 1.5E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 PIRSF PIRSF001554 1 386 8.4E-154 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18005 039dbe2d996cb66b8e47188d60bfa8e6 386 SUPERFAMILY SSF52210 239 386 3.01E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 SUPERFAMILY SSF81330 10 118 9.15E-32 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 3.3E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 3.3E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 3.3E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 126 27.958 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 5.3E-41 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS01565 a30f84beae306408cf4617c1edcf3bd9 129 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 3.7E-45 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A21D_RS04810 ed4f3ad54038568b01e12049ede7f4f2 281 SUPERFAMILY SSF55681 15 264 7.21E-65 T 28-03-2018 A21D_RS04810 ed4f3ad54038568b01e12049ede7f4f2 281 Gene3D G3DSA:3.30.930.10 7 275 1.1E-38 T 28-03-2018 A21D_RS04810 ed4f3ad54038568b01e12049ede7f4f2 281 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 281 44.594 T 28-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 A21D_RS04810 ed4f3ad54038568b01e12049ede7f4f2 281 Pfam PF03099 Biotin/lipoate A/B protein ligase family 79 186 4.4E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 333 1.4E-120 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 Gene3D G3DSA:3.30.390.10 1 106 3.4E-22 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 SUPERFAMILY SSF54826 3 126 3.18E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 125 8.8E-14 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 Gene3D G3DSA:3.20.20.120 107 348 7.5E-65 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 SMART SM00922 143 235 5.4E-24 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 Pfam PF13378 Enolase C-terminal domain-like 146 352 1.3E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 SUPERFAMILY SSF51604 114 364 1.03E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A21D_RS12370 f50fde2078523c3d24b6c74cbb8b35a3 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 360 44.098 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 PIRSF PIRSF004749 2 183 3.3E-46 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 Gene3D G3DSA:3.90.45.10 3 183 1.4E-52 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 Pfam PF01327 Polypeptide deformylase 4 171 4.3E-45 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 PRINTS PR01576 Peptide deformylase signature 140 169 3.3E-31 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 PRINTS PR01576 Peptide deformylase signature 108 119 3.3E-31 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 PRINTS PR01576 Peptide deformylase signature 121 139 3.3E-31 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 PRINTS PR01576 Peptide deformylase signature 47 76 3.3E-31 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.267 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 177 1.7E-47 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS18675 cef64205f5e39eb5d2e95251a2c27fdd 183 SUPERFAMILY SSF56420 2 180 1.57E-59 T 28-03-2018 IPR023635 Peptide deformylase A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 SUPERFAMILY SSF51735 2 149 5.0E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 Pfam PF00106 short chain dehydrogenase 5 147 1.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 Gene3D G3DSA:3.40.50.720 1 173 1.3E-27 T 28-03-2018 A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04970 61121f035274b74a692fc4da4d7c661d 182 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS14060 93a631136817904ed98df89f22c9e33b 128 Pfam PF03061 Thioesterase superfamily 37 111 9.4E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS14060 93a631136817904ed98df89f22c9e33b 128 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 7 121 4.8E-38 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A21D_RS14060 93a631136817904ed98df89f22c9e33b 128 SUPERFAMILY SSF54637 5 126 2.49E-27 T 28-03-2018 IPR029069 HotDog domain A21D_RS14060 93a631136817904ed98df89f22c9e33b 128 Gene3D G3DSA:3.10.129.10 2 128 1.7E-23 T 28-03-2018 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 7 222 40.964 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 SMART SM00987 51 211 1.3E-35 T 28-03-2018 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 Gene3D G3DSA:3.40.470.10 1 224 1.6E-101 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 Pfam PF03167 Uracil DNA glycosylase superfamily 54 210 3.9E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 SUPERFAMILY SSF52141 7 223 2.24E-93 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 215 1.0E-83 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 59 68 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS10710 d0f7ebe03cbc0b0d4ff6b0adbe9713dd 224 SMART SM00986 51 211 1.3E-35 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 SMART SM00220 11 267 1.3E-69 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Gene3D G3DSA:1.10.510.10 79 639 3.1E-58 T 28-03-2018 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Gene3D G3DSA:3.30.200.20 1 78 8.7E-22 T 28-03-2018 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 SUPERFAMILY SSF56112 7 283 6.07E-82 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Pfam PF00069 Protein kinase domain 13 258 2.2E-56 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 SMART SM00740 511 577 5.2E-17 T 28-03-2018 IPR005543 PASTA domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 SMART SM00740 442 510 0.004 T 28-03-2018 IPR005543 PASTA domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 SMART SM00740 375 441 1.6E-19 T 28-03-2018 IPR005543 PASTA domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Pfam PF03793 PASTA domain 379 441 4.2E-15 T 28-03-2018 IPR005543 PASTA domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Pfam PF03793 PASTA domain 516 576 1.1E-15 T 28-03-2018 IPR005543 PASTA domain A21D_RS18180 8dc62c72d6388e3eeb010c40f6cc6249 672 Pfam PF03793 PASTA domain 450 509 4.4E-7 T 28-03-2018 IPR005543 PASTA domain A21D_RS06700 d13d4cce6483595b40dfc9cc00dd6395 126 Pfam PF04977 Septum formation initiator 45 122 2.7E-17 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A21D_RS06700 d13d4cce6483595b40dfc9cc00dd6395 126 Gene3D G3DSA:1.20.58.130 51 98 5.2E-4 T 28-03-2018 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 SUPERFAMILY SSF55681 110 424 8.56E-98 T 28-03-2018 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 Gene3D G3DSA:3.30.930.10 101 430 3.4E-94 T 28-03-2018 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 3.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 3.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 3.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 3.6E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 6.1E-164 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 1.2E-82 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 SUPERFAMILY SSF50249 10 102 5.78E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 Gene3D G3DSA:2.40.50.140 2 100 1.3E-19 T 28-03-2018 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 1.8E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A21D_RS16750 e784a7cb6b953ae203955cbe309ec1ce 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.085 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SUPERFAMILY SSF54106 52 94 1.22E-6 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SMART SM00257 3 47 6.3E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SMART SM00257 52 94 1.5E-4 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Pfam PF00704 Glycosyl hydrolases family 18 148 408 2.2E-22 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SUPERFAMILY SSF51445 126 321 9.49E-41 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SUPERFAMILY SSF51445 382 425 9.49E-41 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Pfam PF01476 LysM domain 56 94 2.4E-7 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Pfam PF01476 LysM domain 4 47 2.0E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SUPERFAMILY SSF54106 2 47 5.49E-10 T 28-03-2018 IPR018392 LysM domain A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 SMART SM00636 101 410 3.6E-21 T 28-03-2018 IPR011583 Chitinase II GO:0008061 A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Gene3D G3DSA:3.10.350.10 50 99 2.0E-8 T 28-03-2018 A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Gene3D G3DSA:3.20.20.80 100 422 1.0E-42 T 28-03-2018 A21D_RS06925 a4f4dbafeb81ec5edab8898039620a17 428 Gene3D G3DSA:3.10.350.10 1 48 1.5E-11 T 28-03-2018 A21D_RS06645 2666a3fffad5480d25077fb20e490d6d 299 SUPERFAMILY SSF109998 42 192 1.1E-16 T 28-03-2018 IPR027304 Trigger factor/SurA domain A21D_RS06645 2666a3fffad5480d25077fb20e490d6d 299 Gene3D G3DSA:3.10.50.40 154 281 1.1E-17 T 28-03-2018 A21D_RS06645 2666a3fffad5480d25077fb20e490d6d 299 Pfam PF13616 PPIC-type PPIASE domain 162 239 4.6E-8 T 28-03-2018 A21D_RS06645 2666a3fffad5480d25077fb20e490d6d 299 SUPERFAMILY SSF54534 160 255 4.0E-13 T 28-03-2018 A21D_RS06645 2666a3fffad5480d25077fb20e490d6d 299 Gene3D G3DSA:1.10.4030.10 37 135 4.5E-7 T 28-03-2018 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 SMART SM00866 92 231 2.4E-30 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 70 1.4E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 6.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 6.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 Gene3D G3DSA:1.10.10.10 1 69 6.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 SMART SM00345 11 70 8.7E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 SUPERFAMILY SSF64288 58 237 6.91E-45 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 SUPERFAMILY SSF46785 3 80 1.61E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 Pfam PF07702 UTRA domain 93 229 2.0E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS04390 205c3ab0c4af8ea2cb40e4d217f9b879 241 Gene3D G3DSA:3.40.1410.10 70 238 7.3E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS10895 ca2e58131f6150d6571fa5a9937b473c 390 PIRSF PIRSF004925 2 384 4.4E-69 T 28-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter A21D_RS10895 ca2e58131f6150d6571fa5a9937b473c 390 Gene3D G3DSA:1.20.1250.20 186 388 6.2E-22 T 28-03-2018 A21D_RS10895 ca2e58131f6150d6571fa5a9937b473c 390 Pfam PF12832 MFS_1 like family 8 359 1.2E-58 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain A21D_RS10895 ca2e58131f6150d6571fa5a9937b473c 390 Gene3D G3DSA:1.20.1250.20 3 182 9.5E-20 T 28-03-2018 A21D_RS10895 ca2e58131f6150d6571fa5a9937b473c 390 SUPERFAMILY SSF103473 10 381 1.48E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 3.4E-108 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Gene3D G3DSA:3.30.930.10 137 589 1.8E-108 T 28-03-2018 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Pfam PF02938 GAD domain 314 408 3.6E-31 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Gene3D G3DSA:2.40.50.140 11 114 3.4E-26 T 28-03-2018 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 SUPERFAMILY SSF50249 7 109 5.14E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 SUPERFAMILY SSF55681 115 298 4.15E-108 T 28-03-2018 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 SUPERFAMILY SSF55681 427 588 4.15E-108 T 28-03-2018 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 SUPERFAMILY SSF55261 295 422 5.56E-43 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 587 34.07 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 Pfam PF01336 OB-fold nucleic acid binding domain 21 106 1.2E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A21D_RS15360 089fc67661988fb2b442ff6d5a7f4b32 593 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 586 4.3E-251 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Pfam PF01751 Toprim domain 426 537 4.0E-19 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 13 641 0.0 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Gene3D G3DSA:3.30.230.10 229 399 1.0E-63 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 249 267 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 367 381 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 381 401 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 610 626 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 13 23 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 477 486 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 203 216 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 319 335 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 188 203 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR01159 DNA gyrase subunit B signature 594 606 7.9E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 571 630 4.7E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 SUPERFAMILY SSF55874 13 220 6.02E-73 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 SUPERFAMILY SSF54211 229 398 2.09E-60 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 SMART SM00433 42 634 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 181 1.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 275 288 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 531 543 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 42 57 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 573 589 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 77 90 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 511 528 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 493 509 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 427 441 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 PRINTS PR00418 DNA topoisomerase II family signature 120 134 4.1E-73 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 SUPERFAMILY SSF56719 401 633 1.54E-92 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Gene3D G3DSA:3.30.565.10 25 228 9.8E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Gene3D G3DSA:3.40.50.670 406 638 1.9E-104 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 SMART SM00387 38 182 3.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 10 641 96.336 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS07205 e01f860d35883f575823e4936206e1f8 641 Pfam PF00204 DNA gyrase B 229 397 4.4E-61 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS01815 373300cfdacc52381c2775bc61761aa1 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 1.3E-8 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS01815 373300cfdacc52381c2775bc61761aa1 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 9 44 1.6E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS01815 373300cfdacc52381c2775bc61761aa1 171 SUPERFAMILY SSF51161 4 167 7.21E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS01815 373300cfdacc52381c2775bc61761aa1 171 Gene3D G3DSA:2.160.10.10 1 171 9.7E-43 T 28-03-2018 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 SUPERFAMILY SSF48019 239 421 4.14E-71 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Gene3D G3DSA:3.40.50.300 1 139 8.2E-26 T 28-03-2018 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Pfam PF16193 AAA C-terminal domain 174 253 6.1E-25 T 28-03-2018 IPR032423 AAA C-terminal domain A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Gene3D G3DSA:1.10.8.60 140 229 2.1E-21 T 28-03-2018 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Gene3D G3DSA:1.20.272.10 238 331 2.4E-35 T 28-03-2018 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 129 3.0E-15 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 SMART SM00382 39 151 1.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 SUPERFAMILY SSF52540 4 234 3.5E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 254 420 3.0E-67 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal A21D_RS15375 fb9d938793bd9e11368d9d15ebb39bcf 422 Gene3D G3DSA:1.10.3710.10 334 422 1.2E-30 T 28-03-2018 A21D_RS01375 0f355d7894147c80ec6c5eb640ec2553 293 Gene3D G3DSA:1.10.3720.10 3 280 1.2E-40 T 28-03-2018 A21D_RS01375 0f355d7894147c80ec6c5eb640ec2553 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 287 9.7E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01375 0f355d7894147c80ec6c5eb640ec2553 293 SUPERFAMILY SSF161098 12 293 9.94E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS15210 8cff673225089bae82f36e6559f872ba 290 Pfam PF02163 Peptidase family M50 108 147 5.6E-7 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A21D_RS16380 e705fcdf9dc3ef4afd63e65103b8779b 151 Pfam PF13398 Peptidase M50B-like 9 105 4.0E-6 T 28-03-2018 A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 Pfam PF00326 Prolyl oligopeptidase family 390 595 4.0E-43 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 Gene3D G3DSA:2.140.10.30 6 152 4.4E-12 T 28-03-2018 A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 SUPERFAMILY SSF82171 191 332 2.12E-18 T 28-03-2018 A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 SUPERFAMILY SSF82171 15 141 2.12E-18 T 28-03-2018 A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 Gene3D G3DSA:3.40.50.1820 334 598 1.3E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 SUPERFAMILY SSF53474 345 595 1.59E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05275 952ee350708fa000bb97bc45aa670d4e 598 Gene3D G3DSA:2.130.10.120 161 333 1.6E-12 T 28-03-2018 A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 SMART SM00382 41 233 1.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 3.1E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 SUPERFAMILY SSF52540 6 255 2.13E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 Gene3D G3DSA:3.40.50.300 2 322 1.3E-87 T 28-03-2018 A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 2.7E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS03555 1d95fea4a9322acc0413c4834025984f 322 Pfam PF00005 ABC transporter 33 183 2.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 Gene3D G3DSA:1.10.10.60 39 246 1.4E-8 T 28-03-2018 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 SUPERFAMILY SSF46689 3 68 1.2E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 49 1.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 Gene3D G3DSA:1.10.10.60 2 38 2.5E-15 T 28-03-2018 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04425 09a51bb17c875990e40f02d4218a51ad 291 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS13015 3fc7b84fd64aecaea852a4b63e0dc9d6 117 SUPERFAMILY SSF158622 3 112 4.19E-39 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS13015 3fc7b84fd64aecaea852a4b63e0dc9d6 117 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 4 107 1.3E-25 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A21D_RS13015 3fc7b84fd64aecaea852a4b63e0dc9d6 117 Hamap MF_01526 UPF0342 protein . 1 112 19.619 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A21D_RS13015 3fc7b84fd64aecaea852a4b63e0dc9d6 117 Gene3D G3DSA:1.20.1500.10 3 108 4.3E-30 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS16220 145e3d40d5b680e0a0ee8802d0a5e559 536 Pfam PF13751 Transposase DDE domain 393 518 2.9E-31 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS16220 145e3d40d5b680e0a0ee8802d0a5e559 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS16220 145e3d40d5b680e0a0ee8802d0a5e559 536 Gene3D G3DSA:3.90.350.10 230 497 1.9E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 306 1.3E-80 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 Gene3D G3DSA:3.40.50.1100 30 139 2.2E-31 T 28-03-2018 A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 SUPERFAMILY SSF53686 9 314 4.98E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 Gene3D G3DSA:3.40.50.1100 140 316 1.9E-47 T 28-03-2018 A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 318 7.5E-117 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A21D_RS01415 d1856bfa3886543c83b9fb815ece56fa 332 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 45 58 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 SUPERFAMILY SSF74650 371 881 1.15E-44 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 4 259 3.7E-34 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Gene3D G3DSA:2.60.40.1180 361 497 4.7E-16 T 28-03-2018 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 377 877 1.0E-22 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Gene3D G3DSA:3.20.110.10 1 264 1.5E-44 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 SUPERFAMILY SSF88713 2 263 1.56E-40 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Pfam PF09261 Alpha mannosidase middle domain 271 347 2.6E-8 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 SUPERFAMILY SSF88688 271 371 9.81E-9 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 Gene3D G3DSA:1.20.1270.50 274 360 6.4E-14 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 A21D_RS09410 d624a87c2a80a09ddc7d6c6b97d39be4 882 SMART SM00872 270 348 2.2E-7 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 A21D_RS01075 1023f6ef381e87e41a86deb1766a22bc 421 Pfam PF02378 Phosphotransferase system, EIIC 29 344 1.2E-59 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS01075 1023f6ef381e87e41a86deb1766a22bc 421 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 417 2.5E-122 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS01075 1023f6ef381e87e41a86deb1766a22bc 421 PIRSF PIRSF006351 1 421 2.4E-150 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 Pfam PF01668 SmpB protein 9 150 1.1E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 114 4.0E-50 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 150 2.5E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 76.299 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 SUPERFAMILY SSF74982 3 132 2.09E-53 T 28-03-2018 IPR023620 Small protein B A21D_RS00450 50bea32eff5cc4b9a66a928180d3a0c0 154 Gene3D G3DSA:2.40.280.10 9 127 2.9E-52 T 28-03-2018 IPR023620 Small protein B A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 65 613 3.4E-169 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 SUPERFAMILY SSF56784 305 325 4.46E-47 T 28-03-2018 IPR023214 HAD-like domain A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 SUPERFAMILY SSF56784 366 610 4.46E-47 T 28-03-2018 IPR023214 HAD-like domain A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 SUPERFAMILY SSF81653 118 215 3.92E-26 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 Pfam PF00702 haloacid dehalogenase-like hydrolase 303 524 2.9E-36 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 Pfam PF00122 E1-E2 ATPase 116 287 1.0E-48 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 307 321 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 529 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 445 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 467 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 546 9.8E-25 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 Gene3D G3DSA:1.20.1110.10 60 321 2.4E-32 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 Gene3D G3DSA:3.40.1110.10 322 434 5.7E-23 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 Gene3D G3DSA:3.40.50.1000 435 576 7.6E-36 T 28-03-2018 IPR023214 HAD-like domain A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 SUPERFAMILY SSF81665 67 119 1.57E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 SUPERFAMILY SSF81665 216 301 1.57E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 88 587 1.1E-71 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 65 614 4.5E-140 T 28-03-2018 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 309 315 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00941 Cadmium-transporting ATPase signature 181 197 8.6E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00941 Cadmium-transporting ATPase signature 120 136 8.6E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00941 Cadmium-transporting ATPase signature 200 214 8.6E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00941 Cadmium-transporting ATPase signature 46 58 8.6E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05540 1e25e3c1f157bf1d212db22236add8f5 623 PRINTS PR00941 Cadmium-transporting ATPase signature 100 120 8.6E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS05700 f42156a29fda2706980dae4f7f95e4f1 291 Pfam PF07728 AAA domain (dynein-related subfamily) 54 191 1.7E-23 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A21D_RS05700 f42156a29fda2706980dae4f7f95e4f1 291 Gene3D G3DSA:3.40.50.300 37 197 2.2E-25 T 28-03-2018 A21D_RS05700 f42156a29fda2706980dae4f7f95e4f1 291 SMART SM00382 51 279 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05700 f42156a29fda2706980dae4f7f95e4f1 291 SUPERFAMILY SSF52540 39 267 5.78E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 356 5.3E-140 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 Gene3D G3DSA:2.30.30.280 213 276 1.9E-26 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 SUPERFAMILY SSF52402 4 244 7.72E-61 T 28-03-2018 A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 Gene3D G3DSA:2.40.30.10 278 369 4.5E-30 T 28-03-2018 A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 Pfam PF03054 tRNA methyl transferase 8 356 2.4E-148 T 28-03-2018 A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 Gene3D G3DSA:3.40.50.620 2 212 4.5E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS15390 40fea79598e40ab4c0af8fa3e05487f5 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 357 40.582 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A21D_RS10885 40434a91fe9456dbc3fb1c5ce7844e91 444 Pfam PF00860 Permease family 17 406 1.2E-51 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS10885 40434a91fe9456dbc3fb1c5ce7844e91 444 PIRSF PIRSF005353 1 444 6.5E-175 T 28-03-2018 IPR026033 Purine permease PbuG-like A21D_RS10300 6401c57135612ad5dd52b5f24001bc15 307 Gene3D G3DSA:1.10.10.630 164 238 9.4E-22 T 28-03-2018 IPR034829 DnaD-like domain A21D_RS10300 6401c57135612ad5dd52b5f24001bc15 307 SUPERFAMILY SSF158499 171 232 1.26E-16 T 28-03-2018 IPR006343 DnaD domain A21D_RS10300 6401c57135612ad5dd52b5f24001bc15 307 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 171 238 1.2E-19 T 28-03-2018 IPR006343 DnaD domain A21D_RS10300 6401c57135612ad5dd52b5f24001bc15 307 Pfam PF07261 Replication initiation and membrane attachment 172 239 2.0E-16 T 28-03-2018 IPR006343 DnaD domain A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 SUPERFAMILY SSF56752 314 569 1.24E-41 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 Gene3D G3DSA:3.20.10.10 446 574 1.0E-26 T 28-03-2018 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 Gene3D G3DSA:3.30.470.10 370 445 9.6E-19 T 28-03-2018 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 PRINTS PR00095 Anthranilate synthase component I signature 222 235 5.6E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 PRINTS PR00095 Anthranilate synthase component I signature 300 314 5.6E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 PRINTS PR00095 Anthranilate synthase component I signature 208 221 5.6E-8 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 Pfam PF00425 chorismate binding enzyme 107 360 7.7E-88 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 Gene3D G3DSA:3.60.120.10 82 365 3.1E-107 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 52 362 3.2E-109 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 SUPERFAMILY SSF56322 14 363 1.96E-104 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS19210 37509af5aaa925dac6c1dec1293b782d 575 Pfam PF01063 Amino-transferase class IV 373 569 2.8E-40 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 SUPERFAMILY SSF46785 21 151 1.82E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 SMART SM00347 35 135 4.7E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 Gene3D G3DSA:1.10.10.10 13 135 2.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 7.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 7.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 7.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 7.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05880 5fb986469cb5d7f2ef90be1921829068 154 Pfam PF01047 MarR family 42 100 7.7E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS05060 21d30bcba6eaef034f05f9df69a801ae 451 SUPERFAMILY SSF89260 205 311 2.35E-7 T 28-03-2018 A21D_RS05060 21d30bcba6eaef034f05f9df69a801ae 451 Gene3D G3DSA:2.60.40.10 336 417 4.5E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS05060 21d30bcba6eaef034f05f9df69a801ae 451 Gene3D G3DSA:2.60.120.380 200 317 7.0E-14 T 28-03-2018 A21D_RS05060 21d30bcba6eaef034f05f9df69a801ae 451 Gene3D G3DSA:2.60.120.380 74 199 1.3E-15 T 28-03-2018 A21D_RS05060 21d30bcba6eaef034f05f9df69a801ae 451 SUPERFAMILY SSF89260 81 188 1.1E-5 T 28-03-2018 A21D_RS00245 630de5196425e9e1a0f77b507be1896e 274 SUPERFAMILY SSF53850 31 271 3.43E-71 T 28-03-2018 A21D_RS00245 630de5196425e9e1a0f77b507be1896e 274 PIRSF PIRSF002854 1 272 6.4E-92 T 28-03-2018 IPR004872 Lipoprotein NlpA family A21D_RS00245 630de5196425e9e1a0f77b507be1896e 274 Pfam PF03180 NLPA lipoprotein 32 270 6.5E-81 T 28-03-2018 IPR004872 Lipoprotein NlpA family A21D_RS00245 630de5196425e9e1a0f77b507be1896e 274 Gene3D G3DSA:3.40.190.10 27 122 2.5E-21 T 28-03-2018 A21D_RS00245 630de5196425e9e1a0f77b507be1896e 274 Gene3D G3DSA:3.40.190.10 123 270 5.2E-45 T 28-03-2018 A21D_RS03355 4d44309d8a9d1073dd474fe141969df3 176 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 8 171 2.0E-48 T 28-03-2018 IPR006286 Peptidase C56, PfpI A21D_RS03355 4d44309d8a9d1073dd474fe141969df3 176 Gene3D G3DSA:3.40.50.880 1 176 1.1E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03355 4d44309d8a9d1073dd474fe141969df3 176 SUPERFAMILY SSF52317 7 174 5.26E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03355 4d44309d8a9d1073dd474fe141969df3 176 Pfam PF01965 DJ-1/PfpI family 6 167 4.9E-45 T 28-03-2018 IPR002818 DJ-1/PfpI A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 SUPERFAMILY SSF55874 250 375 2.36E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 Gene3D G3DSA:3.90.20.10 29 197 0.0018 T 28-03-2018 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 377 1.9E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 7.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 7.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 7.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 Pfam PF05384 Sensor protein DegS 11 169 9.3E-57 T 28-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 Gene3D G3DSA:3.30.565.10 244 379 2.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 Pfam PF07730 Histidine kinase 179 247 4.7E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 PIRSF PIRSF003169 1 379 6.1E-159 T 28-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 A21D_RS00920 967d07c3ed90f371f2e34e4482554e02 379 SMART SM00387 285 378 1.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 289 41.607 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 Gene3D G3DSA:3.40.50.300 22 162 1.8E-9 T 28-03-2018 A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 SUPERFAMILY SSF52540 8 163 1.52E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 Gene3D G3DSA:3.40.50.300 1 21 0.23 T 28-03-2018 A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 PIRSF PIRSF005052 7 292 9.0E-109 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A21D_RS00660 78820dedf64cbfe6b6aa96941e2aac8f 293 Pfam PF03668 P-loop ATPase protein family 8 290 7.1E-120 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A21D_RS14595 286917c283242652c81dbe57408ec100 230 Gene3D G3DSA:3.40.50.2300 2 122 6.2E-37 T 28-03-2018 A21D_RS14595 286917c283242652c81dbe57408ec100 230 SMART SM00862 150 226 1.2E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS14595 286917c283242652c81dbe57408ec100 230 Gene3D G3DSA:1.10.10.10 123 230 1.3E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14595 286917c283242652c81dbe57408ec100 230 Pfam PF00072 Response regulator receiver domain 5 115 3.3E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS14595 286917c283242652c81dbe57408ec100 230 SUPERFAMILY SSF46894 128 227 2.64E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS14595 286917c283242652c81dbe57408ec100 230 SUPERFAMILY SSF52172 2 128 3.98E-43 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS14595 286917c283242652c81dbe57408ec100 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 4.4E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS14595 286917c283242652c81dbe57408ec100 230 SMART SM00448 3 114 5.1E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16045 3a06fa918892f1effe64060669549522 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.5E-27 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like A21D_RS16045 3a06fa918892f1effe64060669549522 185 PIRSF PIRSF005901 1 185 4.6E-73 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP A21D_RS16045 3a06fa918892f1effe64060669549522 185 Gene3D G3DSA:2.40.50.140 129 184 4.2E-29 T 28-03-2018 A21D_RS16045 3a06fa918892f1effe64060669549522 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A21D_RS16045 3a06fa918892f1effe64060669549522 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 7.8E-28 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A21D_RS16045 3a06fa918892f1effe64060669549522 185 SUPERFAMILY SSF50249 129 185 7.42E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16045 3a06fa918892f1effe64060669549522 185 SUPERFAMILY SSF50104 1 63 1.68E-21 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS16045 3a06fa918892f1effe64060669549522 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.0E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A21D_RS16045 3a06fa918892f1effe64060669549522 185 Gene3D G3DSA:2.40.50.140 64 127 5.7E-26 T 28-03-2018 A21D_RS16045 3a06fa918892f1effe64060669549522 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.1E-81 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A21D_RS16045 3a06fa918892f1effe64060669549522 185 Gene3D G3DSA:2.30.30.30 2 61 2.8E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A21D_RS16045 3a06fa918892f1effe64060669549522 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.345 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A21D_RS16045 3a06fa918892f1effe64060669549522 185 SUPERFAMILY SSF50249 64 127 1.37E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16045 3a06fa918892f1effe64060669549522 185 SMART SM00841 129 184 9.1E-36 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A21D_RS16045 3a06fa918892f1effe64060669549522 185 SMART SM01185 67 121 5.2E-26 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A21D_RS05575 03c8783eb7902cdb143d2816ae447dc7 149 SMART SM00860 22 136 1.8E-9 T 28-03-2018 IPR018958 Knr4/Smi1-like domain A21D_RS05575 03c8783eb7902cdb143d2816ae447dc7 149 Pfam PF14567 SMI1-KNR4 cell-wall 5 138 3.0E-35 T 28-03-2018 A21D_RS05575 03c8783eb7902cdb143d2816ae447dc7 149 SUPERFAMILY SSF160631 1 147 6.02E-37 T 28-03-2018 A21D_RS05575 03c8783eb7902cdb143d2816ae447dc7 149 Gene3D G3DSA:3.40.1580.10 3 148 1.6E-26 T 28-03-2018 A21D_RS15340 fc9363835f3deeaada4ffd39c75eab54 148 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.818 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A21D_RS15340 fc9363835f3deeaada4ffd39c75eab54 148 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 9.6E-62 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A21D_RS15340 fc9363835f3deeaada4ffd39c75eab54 148 Gene3D G3DSA:3.50.80.10 1 145 3.6E-57 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A21D_RS15340 fc9363835f3deeaada4ffd39c75eab54 148 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.8E-55 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A21D_RS15340 fc9363835f3deeaada4ffd39c75eab54 148 SUPERFAMILY SSF69500 1 145 2.22E-56 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 3.8E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 3.8E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 3.8E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 3.8E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 3.8E-41 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 Gene3D G3DSA:3.30.360.10 163 316 2.3E-65 T 28-03-2018 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 SUPERFAMILY SSF51735 3 179 3.6E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 5 104 1.3E-34 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 PIRSF PIRSF000149 2 335 7.5E-132 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 SMART SM00846 4 153 6.0E-79 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 SUPERFAMILY SSF55347 153 315 1.31E-69 T 28-03-2018 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 Gene3D G3DSA:3.40.50.720 1 162 3.6E-71 T 28-03-2018 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 5 326 2.9E-130 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14620 0c3210a886d8289e5ee033221bedb2c9 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 4.3E-65 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS16795 35a0637f2f2f3edcb75536a2a586a085 104 Pfam PF05103 DivIVA protein 8 62 5.3E-15 T 28-03-2018 IPR007793 DivIVA family A21D_RS16795 35a0637f2f2f3edcb75536a2a586a085 104 PIRSF PIRSF029938 1 101 8.5E-38 T 28-03-2018 IPR011229 Cell cycle protein GpsB A21D_RS16795 35a0637f2f2f3edcb75536a2a586a085 104 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 5.1E-17 T 28-03-2018 IPR019933 DivIVA domain A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.5E-20 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.5E-20 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.5E-20 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 SUPERFAMILY SSF54999 5 102 5.1E-39 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 SMART SM01403 7 101 3.7E-61 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.5E-47 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.253 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 Gene3D G3DSA:3.30.70.600 4 102 1.7E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A21D_RS06380 a5e044f0f3e376f3d7d73f3c0b74075f 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 4.9E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A21D_RS11270 2276bcd91076547b6e6ef9bc3f92b005 111 SUPERFAMILY SSF46973 2 96 4.45E-29 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS11270 2276bcd91076547b6e6ef9bc3f92b005 111 Gene3D G3DSA:1.20.58.80 1 97 5.0E-30 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS11270 2276bcd91076547b6e6ef9bc3f92b005 111 PIRSF PIRSF000699 1 103 3.7E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS11270 2276bcd91076547b6e6ef9bc3f92b005 111 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 5 93 1.6E-29 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS18505 47cbadc7895f5c036b44ae6d7911ce6f 134 SUPERFAMILY SSF101082 15 123 1.03E-5 T 28-03-2018 IPR023220 Type IV secretion system, VirB5-domain A21D_RS18505 47cbadc7895f5c036b44ae6d7911ce6f 134 Gene3D G3DSA:1.20.58.430 7 126 1.7E-5 T 28-03-2018 A21D_RS18505 47cbadc7895f5c036b44ae6d7911ce6f 134 Pfam PF14071 Putative coat protein 12 127 1.8E-35 T 28-03-2018 IPR025953 Putative coat protein YlbD A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 Gene3D G3DSA:1.20.5.50 1043 1143 9.1E-5 T 28-03-2018 A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 Gene3D G3DSA:3.90.20.10 560 724 0.0049 T 28-03-2018 A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 31 357 1.5E-17 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 Gene3D G3DSA:2.60.120.260 921 1042 5.4E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 SUPERFAMILY SSF49265 405 498 6.68E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A21D_RS05450 38365d72b159cdf1d07b00089dc17a67 1473 Gene3D G3DSA:2.60.40.10 399 503 3.6E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 Pfam PF08239 Bacterial SH3 domain 88 136 2.2E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 180 347 7.0E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 Gene3D G3DSA:2.40.50.110 70 138 2.6E-12 T 28-03-2018 A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 SUPERFAMILY SSF53187 178 350 2.92E-52 T 28-03-2018 A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 Gene3D G3DSA:3.40.630.40 159 352 2.4E-56 T 28-03-2018 A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 SMART SM00646 239 347 2.7E-26 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS08850 86c1dc76712e28fe01c8c4c88068e2d0 352 SMART SM00287 78 140 6.7E-5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 Gene3D G3DSA:3.40.640.10 33 280 5.3E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 Gene3D G3DSA:3.90.1150.10 281 398 1.4E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 Pfam PF00266 Aminotransferase class-V 23 391 8.2E-163 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 SUPERFAMILY SSF53383 1 398 3.09E-135 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 PIRSF PIRSF005572 20 404 7.6E-49 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A21D_RS00230 4498b34bf5c6c583a340b7c8e5259d8a 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 4 403 1.1E-191 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 SUPERFAMILY SSF48256 3 372 5.76E-129 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 124 137 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 325 339 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 248 268 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 195 223 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 305 321 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PRINTS PR00143 Citrate synthase signature 173 188 2.8E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 Pfam PF00285 Citrate synthase, C-terminal domain 7 355 1.9E-124 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 372 1.7E-155 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 Gene3D G3DSA:1.10.580.10 12 261 5.3E-83 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 PIRSF PIRSF001369 1 372 3.0E-150 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type A21D_RS14575 6f3bc9386353afa83f876a1d1b2a95ac 372 Gene3D G3DSA:1.10.580.10 300 352 2.4E-11 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS11610 04e988744c02778fcad148163b2efc33 711 SUPERFAMILY SSF52540 401 700 1.75E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Pfam PF07724 AAA domain (Cdc48 subfamily) 451 615 1.9E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 621 699 1.7E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 128 258 1.3E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 486 504 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 219 231 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Gene3D G3DSA:1.10.8.60 635 710 7.6E-21 T 28-03-2018 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 SUPERFAMILY SSF52540 85 376 1.76E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Gene3D G3DSA:3.40.50.300 82 266 9.8E-25 T 28-03-2018 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Pfam PF02151 UvrB/uvrC motif 340 373 8.3E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Gene3D G3DSA:1.10.8.60 268 401 1.2E-36 T 28-03-2018 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 SMART SM00382 123 268 4.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11610 04e988744c02778fcad148163b2efc33 711 SMART SM00382 452 622 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11610 04e988744c02778fcad148163b2efc33 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 456 474 5.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 530 548 5.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 563 577 5.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 501 519 5.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS11610 04e988744c02778fcad148163b2efc33 711 SMART SM01086 621 708 5.2E-29 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS11610 04e988744c02778fcad148163b2efc33 711 Gene3D G3DSA:3.40.50.300 402 634 2.2E-49 T 28-03-2018 A21D_RS18900 904b27cc68e28ec4a0fad40fc30b958c 595 Pfam PF08439 Oligopeptidase F 117 181 1.0E-8 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A21D_RS18900 904b27cc68e28ec4a0fad40fc30b958c 595 SUPERFAMILY SSF55486 54 595 4.03E-92 T 28-03-2018 A21D_RS18900 904b27cc68e28ec4a0fad40fc30b958c 595 Pfam PF01432 Peptidase family M3 205 567 1.5E-18 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A21D_RS18900 904b27cc68e28ec4a0fad40fc30b958c 595 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 8 594 1.6E-196 T 28-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 A21D_RS11600 0d4ec265077be8831f5ae0d47390cd69 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 30 250 3.4E-104 T 28-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA A21D_RS11600 0d4ec265077be8831f5ae0d47390cd69 263 Pfam PF01522 Polysaccharide deacetylase 60 180 6.2E-34 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS11600 0d4ec265077be8831f5ae0d47390cd69 263 SUPERFAMILY SSF88713 47 250 2.72E-63 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS11600 0d4ec265077be8831f5ae0d47390cd69 263 Gene3D G3DSA:3.20.20.370 31 257 7.7E-59 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 SUPERFAMILY SSF53067 33 153 6.48E-29 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 PIRSF PIRSF001267 26 535 2.1E-75 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 SUPERFAMILY SSF53067 157 330 1.81E-41 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 Gene3D G3DSA:3.30.420.150 154 336 2.1E-40 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 Gene3D G3DSA:3.30.420.40 23 153 3.1E-34 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 SUPERFAMILY SSF109604 341 532 1.79E-27 T 28-03-2018 A21D_RS13735 531cd899ce76ed36a168616dd0c89b23 537 Pfam PF02541 Ppx/GppA phosphatase family 50 329 1.8E-51 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 579 7.5E-274 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 SUPERFAMILY SSF46977 443 579 4.06E-47 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 1.7E-6 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.7E-6 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 Gene3D G3DSA:1.20.58.100 447 546 1.4E-28 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 Gene3D G3DSA:3.50.50.60 2 446 1.2E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 SUPERFAMILY SSF56425 231 353 1.64E-31 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 2.8E-44 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 SUPERFAMILY SSF51905 357 427 1.12E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 SUPERFAMILY SSF51905 5 247 1.12E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 Gene3D G3DSA:4.10.80.40 547 579 6.0E-4 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 Pfam PF00890 FAD binding domain 6 392 1.5E-81 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PIRSF PIRSF000171 1 240 1.4E-16 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PIRSF PIRSF000171 340 576 7.5E-18 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 2.1E-9 T 28-03-2018 A21D_RS14830 91364d474e3799ddf5cc14a6fa9d4edb 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.1E-9 T 28-03-2018 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Pfam PF00501 AMP-binding enzyme 10 416 1.3E-113 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Gene3D G3DSA:3.30.300.30 411 511 7.8E-29 T 28-03-2018 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Gene3D G3DSA:2.30.38.10 328 409 1.6E-26 T 28-03-2018 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 2.6E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 SUPERFAMILY SSF56801 8 510 7.72E-161 T 28-03-2018 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 PRINTS PR00154 AMP-binding signature 177 185 9.0E-5 T 28-03-2018 IPR020459 AMP-binding A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 PRINTS PR00154 AMP-binding signature 165 176 9.0E-5 T 28-03-2018 IPR020459 AMP-binding A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Gene3D G3DSA:3.40.50.980 176 327 2.6E-51 T 28-03-2018 A21D_RS13255 4d06bc91b5cd05f20ea662dc88581d47 511 Gene3D G3DSA:3.40.50.980 2 175 2.7E-40 T 28-03-2018 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 SUPERFAMILY SSF51621 4 259 9.42E-103 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 PIRSF PIRSF000388 1 267 2.1E-111 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 258 1.9E-112 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 260 4.3E-107 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 264 42.761 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A21D_RS02190 cfe2d96863f84a227da222391a880f35 280 Gene3D G3DSA:3.20.20.60 2 264 7.8E-83 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SUPERFAMILY SSF161093 290 457 1.83E-51 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Pfam PF00571 CBS domain 210 263 3.2E-8 T 28-03-2018 IPR000644 CBS domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Pfam PF00571 CBS domain 145 202 2.5E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Gene3D G3DSA:1.25.60.10 8 134 3.9E-23 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SUPERFAMILY SSF54631 144 282 1.07E-34 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SUPERFAMILY SSF158791 16 142 8.37E-26 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Gene3D G3DSA:1.10.357.20 285 460 3.3E-41 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SMART SM00116 152 205 0.15 T 28-03-2018 IPR000644 CBS domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SMART SM00116 216 264 3.8E-9 T 28-03-2018 IPR000644 CBS domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Pfam PF03448 MgtE intracellular N domain 41 143 5.7E-20 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Pfam PF01769 Divalent cation transporter 329 450 4.6E-30 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 Gene3D G3DSA:3.10.580.10 135 277 1.5E-23 T 28-03-2018 A21D_RS13530 3aac700efe025f37adfc24c737578976 461 SMART SM00924 41 145 1.9E-23 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A21D_RS13530 3aac700efe025f37adfc24c737578976 461 TIGRFAM TIGR00400 mgtE: magnesium transporter 25 458 5.9E-125 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 SMART SM00740 582 640 6.9E-12 T 28-03-2018 IPR005543 PASTA domain A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 13 640 2.7E-244 T 28-03-2018 IPR011927 Stage V sporulation protein D A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 Gene3D G3DSA:3.90.1310.10 25 217 1.5E-43 T 28-03-2018 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 SUPERFAMILY SSF54184 586 638 1.11E-11 T 28-03-2018 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 SUPERFAMILY SSF56601 172 570 3.82E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 205 5.5E-23 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 Pfam PF00905 Penicillin binding protein transpeptidase domain 248 558 1.5E-79 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 SUPERFAMILY SSF56519 53 220 4.05E-43 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 Gene3D G3DSA:3.40.710.10 218 566 6.0E-92 T 28-03-2018 A21D_RS18410 10db20d339e9bbd1f0ee4b1e269d8f8b 643 Pfam PF03793 PASTA domain 586 639 1.8E-10 T 28-03-2018 IPR005543 PASTA domain A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 267 282 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PRINTS PR01469 Bacterial carbamate kinase signature 212 227 7.9E-65 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 PIRSF PIRSF000723 2 313 2.8E-128 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 Pfam PF00696 Amino acid kinase family 5 295 4.3E-32 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 ProSitePatterns PS01128 Shikimate kinase signature. 170 195 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 TIGRFAM TIGR00746 arcC: carbamate kinase 5 312 6.9E-134 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 Gene3D G3DSA:3.40.1160.10 2 313 5.1E-60 T 28-03-2018 A21D_RS02065 611213d62f45ec8a1385db2b6c5e2ec8 314 SUPERFAMILY SSF53633 4 311 1.96E-87 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Gene3D G3DSA:3.40.50.20 1 123 4.3E-54 T 28-03-2018 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 6.9E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.5E-46 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Gene3D G3DSA:3.30.1490.20 124 209 3.6E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 6.1E-78 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 SUPERFAMILY SSF51246 331 443 7.85E-38 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 SUPERFAMILY SSF56059 83 350 1.59E-66 T 28-03-2018 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 SUPERFAMILY SSF52440 1 113 2.81E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 Gene3D G3DSA:3.30.470.20 210 443 1.4E-97 T 28-03-2018 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 SMART SM00878 336 441 1.3E-48 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS17025 ba10117fdfdbe03ce029d9d15cbe89a1 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 7 193 2.6E-80 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Gene3D G3DSA:3.30.300.10 388 511 4.3E-54 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Pfam PF02540 NAD synthase 207 287 2.8E-7 T 28-03-2018 IPR022310 NAD/GMP synthase A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 4 511 54.704 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 4.8E-6 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 4.8E-6 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 7 21 4.8E-6 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00097 Anthranilate synthase component II signature 51 60 2.4E-5 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00097 Anthranilate synthase component II signature 78 89 2.4E-5 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00097 Anthranilate synthase component II signature 166 179 2.4E-5 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 SUPERFAMILY SSF52317 5 226 1.1E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Pfam PF00117 Glutamine amidotransferase class-I 9 188 2.2E-42 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 SUPERFAMILY SSF52402 186 404 1.76E-61 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Gene3D G3DSA:3.40.50.880 2 218 5.6E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 201 511 1.5E-157 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 SUPERFAMILY SSF54810 391 511 2.35E-51 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.5E-7 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 2.5E-7 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 2.5E-7 T 28-03-2018 A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Gene3D G3DSA:3.40.50.620 219 387 1.6E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS10865 d07f7f9ef14b5569d7fab5d79a767540 511 Pfam PF00958 GMP synthase C terminal domain 419 510 9.0E-44 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A21D_RS00695 c56251259f2af926527b552047a8a883 211 SUPERFAMILY SSF56784 1 208 1.84E-57 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00695 c56251259f2af926527b552047a8a883 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 93 106 4.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS00695 c56251259f2af926527b552047a8a883 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS00695 c56251259f2af926527b552047a8a883 211 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 4.0E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS00695 c56251259f2af926527b552047a8a883 211 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 5 180 4.5E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS00695 c56251259f2af926527b552047a8a883 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 180 5.5E-53 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00695 c56251259f2af926527b552047a8a883 211 Gene3D G3DSA:3.40.50.1000 73 209 3.4E-33 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00695 c56251259f2af926527b552047a8a883 211 Gene3D G3DSA:1.10.150.240 28 72 3.1E-14 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A21D_RS00695 c56251259f2af926527b552047a8a883 211 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 56 174 1.2E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS00695 c56251259f2af926527b552047a8a883 211 Gene3D G3DSA:3.40.50.1000 1 27 0.022 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03620 699655f5ef05287cb69a43ad3d9759ae 245 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 61.894 T 28-03-2018 IPR022822 Lactate utilization protein A GO:0006089 A21D_RS03620 699655f5ef05287cb69a43ad3d9759ae 245 Pfam PF02754 Cysteine-rich domain 131 215 4.8E-17 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS03620 699655f5ef05287cb69a43ad3d9759ae 245 Pfam PF02754 Cysteine-rich domain 4 84 3.3E-13 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS10010 7f7434a93c97eda7fda709d5d8a29db8 336 Gene3D G3DSA:2.50.20.10 18 243 7.4E-26 T 28-03-2018 A21D_RS10010 7f7434a93c97eda7fda709d5d8a29db8 336 SUPERFAMILY SSF89392 28 205 2.94E-13 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 SMART SM00862 148 227 4.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 SUPERFAMILY SSF52172 1 129 9.96E-41 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 SUPERFAMILY SSF46894 129 227 8.79E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 Pfam PF00072 Response regulator receiver domain 4 111 1.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 227 5.5E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 Gene3D G3DSA:3.40.50.2300 1 122 2.9E-36 T 28-03-2018 A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 Gene3D G3DSA:1.10.10.10 123 234 3.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12105 030e7a81e8e177f645c4f0fa255fdd9e 238 SMART SM00448 2 112 1.5E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS18815 ebab9909db5520cc383bb0fee4707a25 136 Pfam PF14183 YwpF-like protein 2 134 1.2E-38 T 28-03-2018 IPR025573 YwpF-like protein A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 Gene3D G3DSA:1.10.10.10 1 83 7.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 Gene3D G3DSA:3.40.190.10 185 258 9.2E-10 T 28-03-2018 A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 SUPERFAMILY SSF53850 88 287 9.93E-32 T 28-03-2018 A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 Gene3D G3DSA:3.40.190.10 84 184 5.7E-17 T 28-03-2018 A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 Pfam PF03466 LysR substrate binding domain 86 286 2.1E-37 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS11060 763fcdbec0f2252a7b1a941a915b9d5c 287 SUPERFAMILY SSF46785 1 109 6.36E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 Gene3D G3DSA:3.90.470.20 1 120 7.5E-33 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 112 7.2E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 118 23.741 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 118 1.7E-30 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 117 2.0E-16 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 118 6.4E-29 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A21D_RS10000 e60cbc7806953801f2852ac368c910b3 120 SUPERFAMILY SSF56214 1 117 1.96E-32 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 Gene3D G3DSA:3.40.50.300 248 492 1.6E-39 T 28-03-2018 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 Pfam PF00005 ABC transporter 22 174 8.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 Pfam PF00005 ABC transporter 274 427 5.8E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 SUPERFAMILY SSF52540 5 225 1.97E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 SUPERFAMILY SSF52540 264 485 2.97E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 Gene3D G3DSA:3.40.50.300 1 238 2.8E-55 T 28-03-2018 A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 SMART SM00382 31 221 3.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10675 91554ee66e3d22e572d0b4f30ae49488 499 SMART SM00382 282 476 1.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 Pfam PF00636 Ribonuclease III domain 12 109 1.3E-15 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 SMART SM00535 3 129 3.3E-4 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 Gene3D G3DSA:1.10.1520.10 1 136 2.5E-20 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 2 128 29.977 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 SUPERFAMILY SSF69065 4 126 2.09E-41 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A21D_RS06475 7368f74b3a96728dfed10ff43df89b03 141 PIRSF PIRSF005520 1 133 7.8E-53 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family A21D_RS00210 e5070dc37745b9e7c03989f7add84355 153 Pfam PF06114 IrrE N-terminal-like domain 30 120 7.1E-7 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A21D_RS01875 6e908f6067898d0a5a5d338e68e95943 105 PIRSF PIRSF030200 1 97 8.9E-26 T 28-03-2018 IPR009359 Phenylacetic acid degradation B A21D_RS01875 6e908f6067898d0a5a5d338e68e95943 105 Pfam PF06243 Phenylacetic acid degradation B 7 91 8.8E-24 T 28-03-2018 IPR009359 Phenylacetic acid degradation B A21D_RS01875 6e908f6067898d0a5a5d338e68e95943 105 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 7 94 9.9E-27 T 28-03-2018 IPR009359 Phenylacetic acid degradation B A21D_RS10440 0af7ce45a68729bf08e1186132885e73 148 Pfam PF09393 Phage tail tube protein 3 141 2.7E-52 T 28-03-2018 IPR018989 Phage tail tube protein A21D_RS10440 0af7ce45a68729bf08e1186132885e73 148 SUPERFAMILY SSF69279 6 142 5.1E-47 T 28-03-2018 A21D_RS12060 6cde887f8a7f99fa937113526408b308 254 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 41.281 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A21D_RS12060 6cde887f8a7f99fa937113526408b308 254 SUPERFAMILY SSF110399 1 240 2.75E-79 T 28-03-2018 A21D_RS12060 6cde887f8a7f99fa937113526408b308 254 Gene3D G3DSA:3.20.20.70 1 254 4.4E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS12060 6cde887f8a7f99fa937113526408b308 254 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 5.0E-108 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A21D_RS18925 b06fe96448ad8062c2de30b2ffd09cb9 166 SUPERFAMILY SSF56801 3 165 7.33E-32 T 28-03-2018 A21D_RS18925 b06fe96448ad8062c2de30b2ffd09cb9 166 Pfam PF13193 AMP-binding enzyme C-terminal domain 83 156 4.6E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS18925 b06fe96448ad8062c2de30b2ffd09cb9 166 Pfam PF00501 AMP-binding enzyme 3 71 6.3E-6 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS18925 b06fe96448ad8062c2de30b2ffd09cb9 166 Gene3D G3DSA:2.30.38.10 1 66 8.2E-8 T 28-03-2018 A21D_RS18925 b06fe96448ad8062c2de30b2ffd09cb9 166 Gene3D G3DSA:3.30.300.30 68 166 6.0E-18 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 639 3.4E-29 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 669 3.2E-43 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 870 1172 2.9E-29 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 SUPERFAMILY SSF57997 670 857 1.77E-7 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 23.827 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:1.20.5.170 172 262 0.22 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:1.20.5.170 787 873 0.098 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:1.20.5.170 715 786 1.2E-5 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 SUPERFAMILY SSF75553 484 688 6.41E-51 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 PIRSF PIRSF005719 1 1187 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 SMART SM00968 520 639 5.0E-33 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:1.10.287.370 455 714 4.8E-5 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 SUPERFAMILY SSF52540 2 214 1.6E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 SUPERFAMILY SSF52540 1078 1164 1.6E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:3.40.50.300 1 171 2.9E-40 T 28-03-2018 A21D_RS18085 80fe03a7f9eec0c6001e5db731ba9228 1188 Gene3D G3DSA:3.40.50.300 949 1184 6.6E-36 T 28-03-2018 A21D_RS08340 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS08340 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS08340 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS08340 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS11165 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS11165 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS11165 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS11165 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS18235 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18235 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS18235 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS18235 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS13455 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS13455 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS13455 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS13455 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS04005 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS04005 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS04005 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS04005 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS12265 c0e488c94e09c6cba110bed5fc692bff 409 SUPERFAMILY SSF53098 63 342 9.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12265 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS12265 c0e488c94e09c6cba110bed5fc692bff 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS12265 c0e488c94e09c6cba110bed5fc692bff 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS05840 cf305f15ba40460454662f958edcbe4b 306 Pfam PF01497 Periplasmic binding protein 39 266 3.8E-42 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS05840 cf305f15ba40460454662f958edcbe4b 306 SUPERFAMILY SSF53807 37 292 3.18E-55 T 28-03-2018 A21D_RS05840 cf305f15ba40460454662f958edcbe4b 306 Gene3D G3DSA:3.40.50.1980 36 137 2.5E-17 T 28-03-2018 A21D_RS05840 cf305f15ba40460454662f958edcbe4b 306 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 3 290 3.4E-128 T 28-03-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 A21D_RS05840 cf305f15ba40460454662f958edcbe4b 306 Gene3D G3DSA:3.40.50.1980 138 296 1.2E-35 T 28-03-2018 A21D_RS05800 23b5d829270524a3dbc3a0819c28fcb0 276 SUPERFAMILY SSF52540 4 231 3.94E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05800 23b5d829270524a3dbc3a0819c28fcb0 276 SMART SM00382 28 225 5.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05800 23b5d829270524a3dbc3a0819c28fcb0 276 Pfam PF00005 ABC transporter 20 167 3.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05800 23b5d829270524a3dbc3a0819c28fcb0 276 Gene3D G3DSA:3.40.50.300 3 275 3.7E-57 T 28-03-2018 A21D_RS05800 23b5d829270524a3dbc3a0819c28fcb0 276 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS15380 ded52a5031ea0f5f314b57a4a641502b 139 Pfam PF02082 Transcriptional regulator 1 82 5.1E-27 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A21D_RS15380 ded52a5031ea0f5f314b57a4a641502b 139 SUPERFAMILY SSF46785 2 127 1.66E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15380 ded52a5031ea0f5f314b57a4a641502b 139 Gene3D G3DSA:1.10.10.10 1 139 9.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15380 ded52a5031ea0f5f314b57a4a641502b 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A21D_RS15380 ded52a5031ea0f5f314b57a4a641502b 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 2.9E-34 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 Gene3D G3DSA:3.40.50.720 145 358 3.5E-41 T 28-03-2018 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 PIRSF PIRSF000188 1 353 3.7E-166 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 346 2.4E-10 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 3.8E-7 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.1E-21 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.1E-21 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.1E-21 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.1E-21 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 SUPERFAMILY SSF53223 4 143 3.2E-48 T 28-03-2018 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 Gene3D G3DSA:3.40.50.10860 1 144 1.5E-54 T 28-03-2018 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 SUPERFAMILY SSF51735 141 345 2.28E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 17 130 3.6E-27 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16180 cfb817edbdf673feeb693bed2075a879 364 SMART SM00839 144 351 2.6E-72 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS02300 8e8b70e4a67a082699f4f4d3578a3de1 126 Gene3D G3DSA:3.10.129.10 2 117 1.2E-6 T 28-03-2018 A21D_RS02300 8e8b70e4a67a082699f4f4d3578a3de1 126 SUPERFAMILY SSF54637 8 102 6.25E-8 T 28-03-2018 IPR029069 HotDog domain A21D_RS19485 4a3496d7b2d8748c5a103fc2e1ef4a53 275 Pfam PF03631 Virulence factor BrkB 21 264 1.4E-56 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS19485 4a3496d7b2d8748c5a103fc2e1ef4a53 275 PIRSF PIRSF035875 2 273 3.5E-60 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS19485 4a3496d7b2d8748c5a103fc2e1ef4a53 275 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 7 263 2.6E-42 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS19220 a5e52a35da8e4d737a7fe88bf6837515 128 Gene3D G3DSA:1.10.440.10 2 113 4.5E-7 T 28-03-2018 IPR024796 T4 endonuclease V A21D_RS19220 a5e52a35da8e4d737a7fe88bf6837515 128 TIGRFAM TIGR02328 TIGR02328: conserved hypothetical protein 1 126 2.5E-58 T 28-03-2018 IPR012650 Conserved hypothetical protein CHP02328 A21D_RS19220 a5e52a35da8e4d737a7fe88bf6837515 128 Pfam PF03013 Pyrimidine dimer DNA glycosylase 1 115 4.2E-35 T 28-03-2018 IPR004260 Pyrimidine dimer DNA glycosylase A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 Gene3D G3DSA:3.40.1190.20 43 310 6.0E-45 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 Pfam PF00294 pfkB family carbohydrate kinase 20 290 1.4E-60 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 Gene3D G3DSA:2.20.150.10 9 42 1.2E-13 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 PIRSF PIRSF000535 1 309 1.0E-105 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 307 6.8E-97 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS04075 2a97a36e55704d735c38e425898aa09d 310 SUPERFAMILY SSF53613 2 289 2.03E-68 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08615 8db80fe8f616f8843cbb8b63ada60996 331 SUPERFAMILY SSF53850 55 325 1.77E-64 T 28-03-2018 A21D_RS08615 8db80fe8f616f8843cbb8b63ada60996 331 Pfam PF12849 PBP superfamily domain 50 301 4.3E-30 T 28-03-2018 IPR024370 PBP domain A21D_RS08615 8db80fe8f616f8843cbb8b63ada60996 331 Gene3D G3DSA:3.40.190.10 55 186 4.3E-34 T 28-03-2018 A21D_RS08615 8db80fe8f616f8843cbb8b63ada60996 331 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 4 314 8.4E-73 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 A21D_RS08615 8db80fe8f616f8843cbb8b63ada60996 331 Gene3D G3DSA:3.40.190.10 187 329 2.3E-11 T 28-03-2018 A21D_RS13175 2721886870afecf8e14f96c6bcf637d3 210 SUPERFAMILY SSF48317 4 200 6.28E-35 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS13175 2721886870afecf8e14f96c6bcf637d3 210 SMART SM00014 83 195 1.2E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS13175 2721886870afecf8e14f96c6bcf637d3 210 Pfam PF01569 PAP2 superfamily 83 199 2.5E-22 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS13175 2721886870afecf8e14f96c6bcf637d3 210 Gene3D G3DSA:1.20.144.10 9 209 7.8E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 SUPERFAMILY SSF89095 295 401 2.18E-36 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 SMART SM00845 326 473 2.8E-77 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 1.0E-184 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 Pfam PF02637 GatB domain 326 473 1.4E-55 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 SUPERFAMILY SSF55931 4 294 2.49E-122 T 28-03-2018 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 Gene3D G3DSA:1.10.10.410 413 474 1.7E-23 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 Pfam PF02934 GatB/GatE catalytic domain 6 285 1.5E-112 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A21D_RS11035 5d5f41c0bf6946d881056a260a09504d 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.416 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 Gene3D G3DSA:1.10.601.10 33 130 1.1E-31 T 28-03-2018 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 Pfam PF04545 Sigma-70, region 4 180 233 7.7E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 SUPERFAMILY SSF88659 143 237 1.38E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 1.5E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 1.5E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 1.5E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 1.5E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 Gene3D G3DSA:1.10.1270.10 153 239 7.8E-21 T 28-03-2018 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 Pfam PF04542 Sigma-70 region 2 62 131 2.2E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 PIRSF PIRSF000770 5 239 4.3E-76 T 28-03-2018 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 1.3E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 6.0E-131 T 28-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 SUPERFAMILY SSF88946 22 131 4.06E-35 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18360 a6807f5ad3c9408d0c1ec0a9e2f8057f 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 Gene3D G3DSA:1.10.10.10 1 74 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 SUPERFAMILY SSF53697 89 256 8.77E-35 T 28-03-2018 A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 Pfam PF01380 SIS domain 115 241 1.8E-22 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 Gene3D G3DSA:3.40.50.10490 75 261 7.9E-32 T 28-03-2018 A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 75 1.6E-16 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS04345 fa702e331ce39b49db1626a02255d3ab 268 SUPERFAMILY SSF46689 2 77 3.76E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 Gene3D G3DSA:3.40.630.10 1 386 2.1E-56 T 28-03-2018 A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 344 5.2E-68 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 SUPERFAMILY SSF53187 278 370 2.05E-59 T 28-03-2018 A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 SUPERFAMILY SSF53187 2 178 2.05E-59 T 28-03-2018 A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 SUPERFAMILY SSF55031 165 270 3.4E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 Pfam PF07687 Peptidase dimerisation domain 173 257 3.4E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS02925 e7803f93b9a44cbebd42b096e15d3b88 386 PIRSF PIRSF037226 1 386 2.4E-162 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted A21D_RS19065 7719c942138774891f991a2444b1a385 138 Gene3D G3DSA:1.20.5.320 18 77 3.7E-4 T 28-03-2018 A21D_RS19065 7719c942138774891f991a2444b1a385 138 Gene3D G3DSA:1.20.5.320 80 138 0.27 T 28-03-2018 A21D_RS19065 7719c942138774891f991a2444b1a385 138 Pfam PF16888 Domain of unknown function (DUF5082) 9 129 1.2E-20 T 28-03-2018 IPR031681 Protein of unknown function DUF5082 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 Gene3D G3DSA:1.10.10.10 1 91 2.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 Pfam PF03466 LysR substrate binding domain 88 293 4.5E-25 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 SUPERFAMILY SSF46785 1 87 9.73E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 Gene3D G3DSA:3.40.190.10 180 265 1.8E-13 T 28-03-2018 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 Gene3D G3DSA:3.40.190.10 92 179 1.1E-12 T 28-03-2018 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05900 476c1d04dafef2310d148f11ccd31c9a 294 SUPERFAMILY SSF53850 90 292 3.68E-24 T 28-03-2018 A21D_RS09095 e2996b84cbac0abd58563ce3901573d1 303 SUPERFAMILY SSF103481 195 290 2.88E-10 T 28-03-2018 A21D_RS09095 e2996b84cbac0abd58563ce3901573d1 303 SUPERFAMILY SSF103481 42 149 4.05E-10 T 28-03-2018 A21D_RS09095 e2996b84cbac0abd58563ce3901573d1 303 TIGRFAM TIGR00688 rarD: protein RarD 8 264 1.2E-70 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 A21D_RS09095 e2996b84cbac0abd58563ce3901573d1 303 Pfam PF00892 EamA-like transporter family 159 283 8.0E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS09095 e2996b84cbac0abd58563ce3901573d1 303 Pfam PF00892 EamA-like transporter family 8 148 3.3E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS13065 48732a1b128f43c815612e6c46eac600 406 Pfam PF01966 HD domain 256 395 1.7E-4 T 28-03-2018 IPR006674 HD domain A21D_RS13065 48732a1b128f43c815612e6c46eac600 406 Gene3D G3DSA:1.10.3210.10 181 406 6.6E-16 T 28-03-2018 A21D_RS13065 48732a1b128f43c815612e6c46eac600 406 SUPERFAMILY SSF109604 334 397 1.41E-10 T 28-03-2018 A21D_RS13065 48732a1b128f43c815612e6c46eac600 406 SUPERFAMILY SSF109604 250 298 1.41E-10 T 28-03-2018 A21D_RS13065 48732a1b128f43c815612e6c46eac600 406 Gene3D G3DSA:2.40.50.140 33 130 6.5E-6 T 28-03-2018 A21D_RS07760 9764c10263934c2f883915acef476608 354 Pfam PF07859 alpha/beta hydrolase fold 107 329 3.8E-46 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A21D_RS07760 9764c10263934c2f883915acef476608 354 SUPERFAMILY SSF53474 82 350 1.86E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07760 9764c10263934c2f883915acef476608 354 Gene3D G3DSA:3.40.50.1820 32 351 8.6E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03880 c0ce572e883146435a5d46f570a36c7d 449 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 432 5.6E-126 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A21D_RS03880 c0ce572e883146435a5d46f570a36c7d 449 PIRSF PIRSF006446 2 449 5.2E-134 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 SUPERFAMILY SSF55890 315 366 1.23E-13 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Pfam PF17203 Single cache domain 3 31 162 3.4E-17 T 28-03-2018 IPR033463 Single cache domain 3 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 SUPERFAMILY SSF103190 30 160 3.61E-29 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Gene3D G3DSA:3.30.450.20 26 155 9.8E-17 T 28-03-2018 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 SUPERFAMILY SSF55874 391 520 1.96E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 520 2.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Gene3D G3DSA:3.30.565.10 370 523 8.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Gene3D G3DSA:3.30.450.20 206 316 0.0048 T 28-03-2018 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 315 365 1.7E-10 T 28-03-2018 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 Gene3D G3DSA:1.10.287.130 317 369 1.2E-14 T 28-03-2018 A21D_RS13615 96af6f526c8e0774f0688b019b19535b 532 SMART SM00387 412 522 1.7E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS19475 af925db307a8522f8d5adbff783fb869 230 Pfam PF00691 OmpA family 96 178 1.6E-12 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS19475 af925db307a8522f8d5adbff783fb869 230 Gene3D G3DSA:3.30.1330.60 64 228 2.4E-27 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS19475 af925db307a8522f8d5adbff783fb869 230 SUPERFAMILY SSF103088 85 213 1.83E-19 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS12020 7275c88a1f6bea29d13f91db9187dda4 94 SUPERFAMILY SSF52794 1 90 1.02E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12020 7275c88a1f6bea29d13f91db9187dda4 94 Gene3D G3DSA:3.40.50.2300 1 93 7.1E-22 T 28-03-2018 A21D_RS12020 7275c88a1f6bea29d13f91db9187dda4 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 80 1.4E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Gene3D G3DSA:3.40.50.300 1 285 6.8E-66 T 28-03-2018 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.7E-14 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Gene3D G3DSA:3.30.70.240 612 689 1.0E-31 T 28-03-2018 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.8E-35 T 28-03-2018 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Gene3D G3DSA:3.30.230.10 490 611 2.2E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.3E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.3E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.3E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SUPERFAMILY SSF50447 263 402 1.3E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SUPERFAMILY SSF54980 402 479 3.24E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SMART SM00889 478 596 1.7E-75 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 111.216 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 2.9E-69 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Gene3D G3DSA:2.40.30.10 292 399 2.7E-30 T 28-03-2018 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Pfam PF00679 Elongation factor G C-terminus 598 684 8.2E-31 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SUPERFAMILY SSF54211 477 597 3.29E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SUPERFAMILY SSF54980 601 688 2.21E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Gene3D G3DSA:3.30.70.870 400 489 6.2E-35 T 28-03-2018 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 4.1E-45 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 Pfam PF03764 Elongation factor G, domain IV 477 595 1.2E-47 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SUPERFAMILY SSF52540 6 279 2.3E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06390 4c2b4ca3355dbff8c836e8b2b0e1f316 692 SMART SM00838 598 685 1.6E-57 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 PIRSF PIRSF004846 1 262 9.4E-68 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 Gene3D G3DSA:3.40.190.10 30 124 6.5E-14 T 28-03-2018 A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 40 257 3.9E-54 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 Pfam PF13531 Bacterial extracellular solute-binding protein 35 258 2.9E-37 T 28-03-2018 A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 SUPERFAMILY SSF53850 34 259 7.72E-53 T 28-03-2018 A21D_RS09280 da672f23f96b4dd9a9103de2fff6a50e 268 Gene3D G3DSA:3.40.190.10 125 216 9.3E-27 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Gene3D G3DSA:2.30.38.10 323 401 3.4E-21 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 SUPERFAMILY SSF56801 4 504 3.66E-148 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Pfam PF00501 AMP-binding enzyme 8 409 5.6E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Gene3D G3DSA:3.40.50.980 2 167 5.8E-42 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Gene3D G3DSA:3.40.50.980 168 322 7.5E-39 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Gene3D G3DSA:3.30.300.30 402 504 9.9E-28 T 28-03-2018 A21D_RS12180 8bcb9d47a9fa910a2e7c1a262dae5d3e 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 493 2.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 SMART SM00283 295 570 1.4E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 520 1.8E-33 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 SUPERFAMILY SSF58104 301 569 2.22E-54 T 28-03-2018 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 SUPERFAMILY SSF58104 246 268 2.22E-54 T 28-03-2018 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 Gene3D G3DSA:1.10.287.950 328 572 2.8E-44 T 28-03-2018 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 Gene3D G3DSA:1.10.287.950 56 327 3.9E-5 T 28-03-2018 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 316 345 2.4E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 23 48 2.4E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 420 2.4E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS08595 7f417f5ecce2f00b9d4b442850354381 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 451 2.4E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 Gene3D G3DSA:2.40.50.140 283 340 2.0E-4 T 28-03-2018 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 SUPERFAMILY SSF52540 5 251 1.09E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 Pfam PF08402 TOBE domain 281 340 1.5E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 Pfam PF00005 ABC transporter 18 168 9.1E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 SMART SM00382 27 218 3.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 Gene3D G3DSA:3.40.50.300 3 263 4.7E-73 T 28-03-2018 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05335 f042bd29ce373be9b3ae7c12c3531ce6 348 SUPERFAMILY SSF50331 244 342 4.42E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A21D_RS10330 6c0b7cad92a916f1e709a293c3290f96 68 Gene3D G3DSA:1.20.5.400 1 64 2.4E-4 T 28-03-2018 A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 SMART SM00450 7 109 4.5E-14 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 Pfam PF00581 Rhodanese-like domain 14 105 1.8E-8 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 Gene3D G3DSA:3.60.15.10 118 372 8.9E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 Pfam PF00753 Metallo-beta-lactamase superfamily 130 271 3.0E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 SMART SM00849 130 294 8.1E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 Gene3D G3DSA:3.40.250.10 2 117 9.5E-19 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 SUPERFAMILY SSF52821 9 110 2.1E-17 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11380 c7eba357b5e91d869343ed9f4dcabc2c 375 SUPERFAMILY SSF56281 124 370 4.06E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 SUPERFAMILY SSF50129 1 181 1.37E-56 T 28-03-2018 IPR011032 GroES-like A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 Gene3D G3DSA:3.90.180.10 1 166 3.8E-53 T 28-03-2018 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 Pfam PF00107 Zinc-binding dehydrogenase 183 309 1.6E-25 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 Gene3D G3DSA:3.40.50.10730 167 283 1.9E-25 T 28-03-2018 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 143 4.4E-36 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 SMART SM00829 10 347 7.3E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 Gene3D G3DSA:3.90.180.10 284 349 3.9E-4 T 28-03-2018 A21D_RS19005 95d7560ac9a9ac28a6e10fbb50b72c13 349 SUPERFAMILY SSF51735 146 314 2.63E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS07500 6fa7e8e012c5145276c482da8e08ca09 189 SMART SM00855 3 146 4.1E-25 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A21D_RS07500 6fa7e8e012c5145276c482da8e08ca09 189 Gene3D G3DSA:3.40.50.1240 1 189 2.1E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A21D_RS07500 6fa7e8e012c5145276c482da8e08ca09 189 SUPERFAMILY SSF53254 2 188 2.5E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A21D_RS07500 6fa7e8e012c5145276c482da8e08ca09 189 PIRSF PIRSF000709 2 155 5.1E-10 T 28-03-2018 A21D_RS07500 6fa7e8e012c5145276c482da8e08ca09 189 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 184 4.4E-49 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Gene3D G3DSA:2.40.50.140 621 705 3.6E-23 T 28-03-2018 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SUPERFAMILY SSF50249 50 131 2.15E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SMART SM00316 622 704 9.8E-20 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Pfam PF00773 RNB domain 244 572 3.9E-114 T 28-03-2018 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 50 704 1.4E-243 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 ProSitePatterns PS01175 Ribonuclease II family signature. 541 565 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Pfam PF08206 Ribonuclease B OB domain 143 197 2.5E-10 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Pfam PF08206 Ribonuclease B OB domain 69 128 3.6E-21 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Pfam PF00575 S1 RNA binding domain 621 703 1.1E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SMART SM00357 136 198 0.003 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SMART SM00357 68 129 1.7E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SMART SM00955 244 574 1.2E-181 T 28-03-2018 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Gene3D G3DSA:2.40.50.140 132 279 1.9E-5 T 28-03-2018 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SUPERFAMILY SSF50249 204 621 3.34E-148 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 704 1.8E-285 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Gene3D G3DSA:2.40.50.140 55 131 6.4E-4 T 28-03-2018 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SUPERFAMILY SSF50249 122 221 1.86E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 SUPERFAMILY SSF50249 622 704 6.29E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Hamap MF_01895 Ribonuclease R [rnr]. 20 704 60.269 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A21D_RS00455 1c5e4c6502708b168bbc3e07ac4069b8 722 Gene3D G3DSA:1.10.10.10 1 54 5.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 SUPERFAMILY SSF55804 496 637 6.67E-27 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:1.10.10.10 88 155 7.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 SUPERFAMILY SSF52794 406 486 2.09E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:1.10.10.10 1 68 2.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF00874 PRD domain 201 280 1.6E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF00874 PRD domain 305 395 1.9E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:1.10.1790.10 170 280 1.2E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:1.10.1790.10 281 399 1.3E-27 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 500 637 2.5E-24 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 SUPERFAMILY SSF63520 184 280 8.5E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:3.40.930.10 495 637 5.2E-27 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Gene3D G3DSA:3.40.50.2300 404 492 1.3E-20 T 28-03-2018 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF05043 Mga helix-turn-helix domain 75 167 6.4E-13 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 410 486 4.1E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 SUPERFAMILY SSF63520 295 398 1.44E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 SUPERFAMILY SSF46894 3 65 7.82E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS02055 cc191e3496b2c9f66153000d54c1d805 637 Pfam PF08279 HTH domain 4 63 7.8E-11 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS14355 dd3ba37844e6f70d77517fe9a6f8ce96 268 SUPERFAMILY SSF103088 135 253 2.22E-31 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS14355 dd3ba37844e6f70d77517fe9a6f8ce96 268 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 56 3.9E-20 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain A21D_RS14355 dd3ba37844e6f70d77517fe9a6f8ce96 268 Pfam PF00691 OmpA family 148 247 3.5E-19 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS14355 dd3ba37844e6f70d77517fe9a6f8ce96 268 Gene3D G3DSA:3.30.1330.60 69 268 4.5E-39 T 28-03-2018 IPR006665 OmpA-like domain A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 SUPERFAMILY SSF53790 2 244 9.42E-79 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 2.4E-52 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 236 3.1E-94 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 Gene3D G3DSA:3.30.950.10 127 253 1.3E-38 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07460 bf974f7d04ee32b8d181269f870f4a26 259 Gene3D G3DSA:3.40.1010.10 1 126 1.4E-38 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 18 33 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 Pfam PF00809 Pterin binding enzyme 19 252 5.1E-86 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 Gene3D G3DSA:3.20.20.20 3 272 9.4E-108 T 28-03-2018 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 18 267 1.3E-99 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 SUPERFAMILY SSF51717 6 269 1.44E-98 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A21D_RS06635 b4754dbfd4e96009602d81e8742f049d 273 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 52 65 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Pfam PF11799 impB/mucB/samB family C-terminal domain 255 361 5.5E-13 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Gene3D G3DSA:3.30.1490.100 258 369 1.1E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 SUPERFAMILY SSF56672 11 246 3.47E-59 T 28-03-2018 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Gene3D G3DSA:3.30.70.270 127 182 1.3E-12 T 28-03-2018 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Gene3D G3DSA:3.30.70.270 50 126 2.7E-10 T 28-03-2018 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 SUPERFAMILY SSF100879 255 355 3.53E-11 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Gene3D G3DSA:1.10.150.20 183 247 3.6E-22 T 28-03-2018 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Pfam PF00817 impB/mucB/samB family 14 164 1.5E-31 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS18945 653e85805d62329c036430dea122bcb3 416 Pfam PF11798 IMS family HHH motif 178 209 3.5E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 8.7E-130 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 PIRSF PIRSF001359 1 285 3.1E-126 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 SUPERFAMILY SSF51569 1 285 9.52E-105 T 28-03-2018 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 6.4E-116 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 6.1E-103 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04690 4a1b4f6e2bc9fbc9f3d7ccd94f66be73 285 Gene3D G3DSA:3.20.20.70 1 285 2.7E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Gene3D G3DSA:3.30.300.30 439 543 1.5E-26 T 28-03-2018 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Gene3D G3DSA:3.40.50.980 201 352 3.8E-55 T 28-03-2018 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 SUPERFAMILY SSF56801 5 540 3.79E-157 T 28-03-2018 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Gene3D G3DSA:2.30.38.10 353 437 1.6E-26 T 28-03-2018 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Pfam PF00501 AMP-binding enzyme 12 444 1.9E-114 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 528 1.5E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS17030 b6625197eee530712b39c5c1a6becbbe 544 Gene3D G3DSA:3.40.50.980 4 200 5.1E-41 T 28-03-2018 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 Gene3D G3DSA:1.20.1560.10 1 322 4.1E-30 T 28-03-2018 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 Pfam PF00664 ABC transporter transmembrane region 19 274 1.7E-17 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 SMART SM00382 365 545 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 SUPERFAMILY SSF52540 333 567 2.82E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 Pfam PF00005 ABC transporter 357 499 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 Gene3D G3DSA:3.40.50.300 323 571 1.9E-62 T 28-03-2018 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 529 1.1E-125 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03865 7e62d5250922fbd17abaafd775a0cf5f 573 SUPERFAMILY SSF90123 8 317 6.41E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 SUPERFAMILY SSF75217 85 244 2.29E-40 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 SUPERFAMILY SSF55315 1 93 3.77E-22 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 Pfam PF00588 SpoU rRNA Methylase family 103 241 3.2E-36 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 SMART SM00967 29 96 2.2E-11 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 Gene3D G3DSA:3.40.1280.10 94 245 1.9E-41 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 29 94 4.0E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A21D_RS14740 79a6c568ddec9b4ca5a423204e98dbee 245 Gene3D G3DSA:3.30.1330.30 1 93 8.1E-21 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 PIRSF PIRSF002181 1 143 1.5E-51 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 Pfam PF00572 Ribosomal protein L13 15 139 2.0E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 SUPERFAMILY SSF52161 5 143 2.49E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.731 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 Gene3D G3DSA:3.90.1180.10 1 145 1.6E-62 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A21D_RS06210 82cf6db04835461b0fc74a6a14e9ec17 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 3.1E-65 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 SUPERFAMILY SSF46689 4 75 3.94E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 Gene3D G3DSA:1.10.10.10 3 118 3.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 75 3.2E-18 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 Pfam PF01380 SIS domain 121 223 9.9E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 SUPERFAMILY SSF53697 97 253 2.22E-26 T 28-03-2018 A21D_RS08545 2da301da2ca4c92f656301e5319c2d59 259 Gene3D G3DSA:3.40.50.10490 119 241 6.2E-17 T 28-03-2018 A21D_RS04485 b080e662d957fe8d3899e065c9860b96 328 SUPERFAMILY SSF54001 182 306 1.77E-36 T 28-03-2018 A21D_RS04485 b080e662d957fe8d3899e065c9860b96 328 Pfam PF00877 NlpC/P60 family 198 304 2.0E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A21D_RS04485 b080e662d957fe8d3899e065c9860b96 328 Gene3D G3DSA:2.30.30.40 42 114 2.1E-7 T 28-03-2018 A21D_RS04485 b080e662d957fe8d3899e065c9860b96 328 Gene3D G3DSA:3.90.1720.10 182 307 1.4E-32 T 28-03-2018 A21D_RS05360 ffbe6368df270762b85f3cbe21e356c5 275 Pfam PF02811 PHP domain 4 66 8.5E-9 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS05360 ffbe6368df270762b85f3cbe21e356c5 275 SUPERFAMILY SSF89550 163 247 1.7E-42 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS05360 ffbe6368df270762b85f3cbe21e356c5 275 SUPERFAMILY SSF89550 1 81 1.7E-42 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS05360 ffbe6368df270762b85f3cbe21e356c5 275 SMART SM00481 3 68 9.4E-16 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS05360 ffbe6368df270762b85f3cbe21e356c5 275 Gene3D G3DSA:3.20.20.140 1 271 5.8E-40 T 28-03-2018 A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 SUPERFAMILY SSF88946 16 97 2.35E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 10 239 27.783 T 28-03-2018 IPR014244 RNA polymerase sigma-I type A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 Gene3D G3DSA:1.10.1740.10 15 98 7.4E-11 T 28-03-2018 A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 Pfam PF04542 Sigma-70 region 2 29 99 1.1E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 PIRSF PIRSF038953 4 242 4.1E-63 T 28-03-2018 IPR014244 RNA polymerase sigma-I type A21D_RS12900 d3d3b1639b3d487de3e21067a923be32 242 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 15 237 1.1E-81 T 28-03-2018 IPR014244 RNA polymerase sigma-I type A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 Pfam PF01048 Phosphorylase superfamily 22 268 1.4E-54 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 7.6E-110 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 SUPERFAMILY SSF53167 4 272 2.49E-100 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 Gene3D G3DSA:3.40.50.1580 1 271 1.8E-73 T 28-03-2018 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 269 1.0E-117 T 28-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A21D_RS16325 7cfc8d8726b2fb969d2e97f4f0825d6b 276 PIRSF PIRSF000477 1 271 6.1E-116 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A21D_RS15305 49d003d55bd8b1039924f4951fe2e94a 516 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 492 1.6E-172 T 28-03-2018 IPR014249 Sporulation stage V protein B A21D_RS15305 49d003d55bd8b1039924f4951fe2e94a 516 PIRSF PIRSF038958 1 515 1.3E-163 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A21D_RS15305 49d003d55bd8b1039924f4951fe2e94a 516 Pfam PF01943 Polysaccharide biosynthesis protein 6 307 2.5E-55 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A21D_RS15305 49d003d55bd8b1039924f4951fe2e94a 516 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 499 5.1E-14 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 SUPERFAMILY SSF56655 10 261 1.3E-66 T 28-03-2018 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 Pfam PF00459 Inositol monophosphatase family 9 262 2.9E-60 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 Gene3D G3DSA:3.30.540.10 2 145 1.9E-36 T 28-03-2018 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00378 Lithium-sensitive myo-inositol monophosphatase family signature 241 263 1.1E-5 T 28-03-2018 IPR020552 Inositol monophosphatase, Lithium-sensitive GO:0046854 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363|Reactome: R-HSA-1855183 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00378 Lithium-sensitive myo-inositol monophosphatase family signature 137 155 1.1E-5 T 28-03-2018 IPR020552 Inositol monophosphatase, Lithium-sensitive GO:0046854 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363|Reactome: R-HSA-1855183 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00378 Lithium-sensitive myo-inositol monophosphatase family signature 20 39 1.1E-5 T 28-03-2018 IPR020552 Inositol monophosphatase, Lithium-sensitive GO:0046854 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363|Reactome: R-HSA-1855183 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 216 230 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 135 158 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 213 237 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 182 203 1.0E-32 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS18605 81fd76da63bc335c30b6eff3a4919263 269 Gene3D G3DSA:3.40.190.80 154 269 2.8E-23 T 28-03-2018 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 Gene3D G3DSA:2.40.100.10 3 145 2.5E-46 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 4.6E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 4.6E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 4.6E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 4.6E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 4.6E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 12 138 4.4E-39 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 PIRSF PIRSF001467 5 145 7.5E-38 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A21D_RS16375 cc124d2aa570fce04cf993ba233530af 145 SUPERFAMILY SSF50891 14 138 1.04E-43 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SUPERFAMILY SSF48371 211 372 1.68E-35 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SUPERFAMILY SSF110836 1 86 1.7E-20 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Gene3D G3DSA:1.25.40.70 186 293 1.5E-14 T 28-03-2018 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Gene3D G3DSA:1.25.40.70 294 359 1.2E-15 T 28-03-2018 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SMART SM00932 4 91 6.7E-20 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SMART SM00567 E-Z type HEAT repeats 312 341 5.8E-4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SMART SM00567 E-Z type HEAT repeats 250 279 0.024 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 SMART SM00567 E-Z type HEAT repeats 281 310 1.7 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Pfam PF13769 Virulence factor 113 193 7.6E-29 T 28-03-2018 IPR025989 Virulence factor domain A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 85 1.2E-17 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Gene3D G3DSA:3.30.1370.70 2 89 7.0E-17 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS03740 04414ef086075633bfd8b51bb56856bf 380 Pfam PF13646 HEAT repeats 269 354 4.6E-15 T 28-03-2018 A21D_RS16885 786f325c1cae2b6cefe52e660b6ade1c 71 Hamap MF_01538 UPF0346 protein . 1 70 21.546 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 A21D_RS16885 786f325c1cae2b6cefe52e660b6ade1c 71 Pfam PF06855 YozE SAM-like fold 3 67 2.3E-26 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS16885 786f325c1cae2b6cefe52e660b6ade1c 71 SUPERFAMILY SSF140652 2 69 1.57E-26 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS16885 786f325c1cae2b6cefe52e660b6ade1c 71 Gene3D G3DSA:1.10.150.260 2 70 1.7E-25 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS16885 786f325c1cae2b6cefe52e660b6ade1c 71 PIRSF PIRSF037262 1 71 3.2E-32 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 1.6E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 Gene3D G3DSA:1.10.10.10 132 233 7.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 SMART SM00862 152 227 2.2E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 Gene3D G3DSA:3.40.50.2300 8 131 1.7E-37 T 28-03-2018 A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 SUPERFAMILY SSF52172 9 183 5.98E-44 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 Pfam PF00072 Response regulator receiver domain 11 116 4.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS05295 573b9ca2de91dc065f72446de59ffb06 236 SMART SM00448 9 119 6.0E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 Gene3D G3DSA:3.20.20.70 12 466 2.6E-19 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 PIRSF PIRSF004911 3 402 1.6E-158 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 23 429 5.2E-192 T 28-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 Pfam PF12544 Lysine-2,3-aminomutase 323 449 1.1E-60 T 28-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 SUPERFAMILY SSF102114 116 358 4.71E-33 T 28-03-2018 A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 Pfam PF13353 4Fe-4S single cluster domain 129 204 5.2E-6 T 28-03-2018 A21D_RS11940 6f0c34e7374302ab554953305f27d934 466 TIGRFAM TIGR00238 TIGR00238: KamA family protein 16 344 1.1E-145 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A21D_RS09400 751e41fc226eff8d02ba46db7f085531 298 SUPERFAMILY SSF53067 3 295 5.1E-56 T 28-03-2018 A21D_RS09400 751e41fc226eff8d02ba46db7f085531 298 Pfam PF00480 ROK family 4 292 4.0E-48 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS09400 751e41fc226eff8d02ba46db7f085531 298 Gene3D G3DSA:3.40.367.20 110 285 5.0E-43 T 28-03-2018 A21D_RS09400 751e41fc226eff8d02ba46db7f085531 298 Gene3D G3DSA:3.30.420.40 1 109 7.9E-26 T 28-03-2018 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 Gene3D G3DSA:3.40.50.1980 31 237 7.7E-50 T 28-03-2018 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 PRINTS PR00690 Adhesin family signature 86 103 9.1E-5 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 PRINTS PR00690 Adhesin family signature 73 86 9.1E-5 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 Pfam PF01297 Zinc-uptake complex component A periplasmic 46 356 9.8E-70 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 SUPERFAMILY SSF53807 180 358 2.59E-77 T 28-03-2018 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 SUPERFAMILY SSF53807 16 139 2.59E-77 T 28-03-2018 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 Gene3D G3DSA:3.40.50.1980 238 358 3.8E-34 T 28-03-2018 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 PRINTS PR00691 Adhesin B signature 42 63 2.6E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 PRINTS PR00691 Adhesin B signature 67 85 2.6E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS10880 eeea5cd2878940fd2bf47e1836b09d35 386 PRINTS PR00691 Adhesin B signature 86 105 2.6E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.8E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.6E-40 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.522 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 SUPERFAMILY SSF50249 1 71 1.69E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 SMART SM00316 4 72 4.0E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS06260 36c1196353857ab78e6318271fd46c1f 72 Gene3D G3DSA:2.40.50.140 1 72 1.4E-38 T 28-03-2018 A21D_RS18020 d49ff170cb737a07bbefcd6390bec72c 256 SUPERFAMILY SSF53098 61 256 3.34E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18020 d49ff170cb737a07bbefcd6390bec72c 256 Hamap MF_00052_B Ribonuclease HII [rnhB]. 72 251 35.522 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 A21D_RS18020 d49ff170cb737a07bbefcd6390bec72c 256 Gene3D G3DSA:3.30.420.10 48 256 2.5E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18020 d49ff170cb737a07bbefcd6390bec72c 256 Pfam PF01351 Ribonuclease HII 74 250 5.5E-41 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain A21D_RS10965 620f7b51e2f704bb79d02bd888eec1a1 191 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 5 188 7.3E-65 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A21D_RS10965 620f7b51e2f704bb79d02bd888eec1a1 191 Pfam PF00551 Formyl transferase 5 180 1.3E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS10965 620f7b51e2f704bb79d02bd888eec1a1 191 Gene3D G3DSA:3.40.50.170 1 191 1.1E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS10965 620f7b51e2f704bb79d02bd888eec1a1 191 SUPERFAMILY SSF53328 5 187 6.28E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS10965 620f7b51e2f704bb79d02bd888eec1a1 191 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 5 187 29.463 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 Pfam PF07690 Major Facilitator Superfamily 9 340 2.4E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 Gene3D G3DSA:1.20.1250.20 1 189 5.1E-28 T 28-03-2018 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 SUPERFAMILY SSF103473 4 378 3.79E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 Gene3D G3DSA:1.20.1250.20 190 380 1.7E-22 T 28-03-2018 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 40 59 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 71 95 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 264 285 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 10 26 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 158 178 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS08075 2675e8ed3c1da051e2e2e0b6dcce4b5e 389 PRINTS PR01035 Tetracycline resistance protein signature 98 119 4.8E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A21D_RS13085 3be8b0d57f8fc610633045dd1d80d647 183 Pfam PF11667 Putative zincin peptidase 60 165 1.1E-18 T 28-03-2018 IPR021683 Putative zincin peptidase A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 PIRSF PIRSF000441 1 218 2.7E-84 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 SUPERFAMILY SSF51161 4 175 1.94E-57 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 153 1.6E-5 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 110 0.0023 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 128 156 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 168 2.0E-77 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 Gene3D G3DSA:1.10.3130.10 2 60 3.1E-26 T 28-03-2018 A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 Pfam PF06426 Serine acetyltransferase, N-terminal 4 37 8.2E-6 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A21D_RS06485 6ba1f9f806afa0956f7e46cf345e2e6c 220 Gene3D G3DSA:2.160.10.10 61 220 6.3E-39 T 28-03-2018 A21D_RS16125 aaad3fa9443375f876adf8dc10d25425 290 Gene3D G3DSA:1.10.600.10 1 290 3.6E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS16125 aaad3fa9443375f876adf8dc10d25425 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A21D_RS16125 aaad3fa9443375f876adf8dc10d25425 290 SUPERFAMILY SSF48576 4 269 8.87E-85 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS16125 aaad3fa9443375f876adf8dc10d25425 290 Pfam PF00348 Polyprenyl synthetase 28 261 1.1E-57 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A21D_RS16125 aaad3fa9443375f876adf8dc10d25425 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 94 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1163 58.496 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Gene3D G3DSA:3.40.50.300 274 702 1.3E-29 T 28-03-2018 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 SUPERFAMILY SSF52540 305 750 8.82E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Gene3D G3DSA:3.40.50.300 121 273 1.5E-34 T 28-03-2018 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Gene3D G3DSA:3.40.50.300 1 120 2.7E-29 T 28-03-2018 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1162 0.0 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Pfam PF12705 PD-(D/E)XK nuclease superfamily 791 1132 3.8E-56 T 28-03-2018 A21D_RS13285 6bccda8647c4c61134e00e879fc63689 1165 Gene3D G3DSA:3.90.320.10 705 1011 9.0E-11 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A21D_RS03045 a85c7753c439de893fb3a5c4f98be838 240 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 231 4.9E-86 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A21D_RS03045 a85c7753c439de893fb3a5c4f98be838 240 Gene3D G3DSA:3.20.20.70 2 240 9.2E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03045 a85c7753c439de893fb3a5c4f98be838 240 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 35.581 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A21D_RS03045 a85c7753c439de893fb3a5c4f98be838 240 SUPERFAMILY SSF51366 1 232 3.77E-69 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS03045 a85c7753c439de893fb3a5c4f98be838 240 Pfam PF00977 Histidine biosynthesis protein 3 227 9.8E-79 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PIRSF PIRSF000149 1 334 1.2E-142 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 Gene3D G3DSA:3.30.360.10 162 315 2.3E-75 T 28-03-2018 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.2E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.2E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.2E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.2E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.2E-40 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.4E-73 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 SMART SM00846 3 152 4.1E-99 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 SUPERFAMILY SSF51735 1 179 4.93E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 Gene3D G3DSA:3.40.50.720 1 161 1.0E-82 T 28-03-2018 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 6.3E-144 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.8E-40 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00525 a6551f6171e1ec5c0ca3b5c23afd51a5 335 SUPERFAMILY SSF55347 152 314 1.58E-76 T 28-03-2018 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 57 94 5.0E-16 T 28-03-2018 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 ProSitePatterns PS00359 Ribosomal protein L11 signature. 147 162 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 Pfam PF00298 Ribosomal protein L11, RNA binding domain 92 160 3.1E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 SUPERFAMILY SSF46906 88 161 4.45E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 SMART SM00649 30 161 6.4E-88 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 Gene3D G3DSA:1.10.10.250 93 161 1.8E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 Gene3D G3DSA:3.30.1550.10 24 92 1.4E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 26 162 31.82 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 SUPERFAMILY SSF54747 22 105 3.14E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 24 162 1.1E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06440 086df7b9620f8c5ec0396732401d079e 162 Pfam PF03946 Ribosomal protein L11, N-terminal domain 30 87 2.3E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A21D_RS13125 f8bb27a5b74fe9203cd8abee1db8e6a2 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 170 7.0E-45 T 28-03-2018 A21D_RS13125 f8bb27a5b74fe9203cd8abee1db8e6a2 173 Pfam PF17099 Tryptophan transporter TrpP 2 165 5.2E-41 T 28-03-2018 IPR031360 Tryptophan transporter TrpP A21D_RS02030 72c4647d3b2f160d8c571b7b556a8790 117 Gene3D G3DSA:1.20.58.80 1 99 5.4E-29 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS02030 72c4647d3b2f160d8c571b7b556a8790 117 PIRSF PIRSF000699 1 105 1.4E-29 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS02030 72c4647d3b2f160d8c571b7b556a8790 117 SUPERFAMILY SSF46973 1 98 6.41E-27 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS02030 72c4647d3b2f160d8c571b7b556a8790 117 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 97 3.0E-27 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 SUPERFAMILY SSF51556 203 495 3.06E-30 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 SUPERFAMILY SSF51556 65 128 3.06E-30 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 Gene3D G3DSA:3.20.20.140 190 493 4.6E-40 T 28-03-2018 A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 Gene3D G3DSA:2.30.40.10 5 150 4.0E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 SUPERFAMILY SSF51338 495 536 4.57E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 SUPERFAMILY SSF51338 7 66 4.57E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS11885 dd52f6082dfde9d513bffaf19250bda5 538 Pfam PF07969 Amidohydrolase family 54 536 2.8E-92 T 28-03-2018 IPR013108 Amidohydrolase 3 A21D_RS04045 a016804a319b905d04924beb2f330072 150 Pfam PF06445 GyrI-like small molecule binding domain 1 150 1.3E-22 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain A21D_RS04045 a016804a319b905d04924beb2f330072 150 SMART SM00871 1 150 4.7E-24 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding A21D_RS04045 a016804a319b905d04924beb2f330072 150 Gene3D G3DSA:3.20.80.10 1 150 4.9E-24 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain A21D_RS04045 a016804a319b905d04924beb2f330072 150 SUPERFAMILY SSF55136 1 150 1.64E-28 T 28-03-2018 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 PIRSF PIRSF001586 1 222 8.9E-86 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 43.797 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 Gene3D G3DSA:3.40.50.880 1 225 1.1E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 1.1E-39 T 28-03-2018 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 217 4.3E-94 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 SMART SM01211 1 219 4.7E-122 T 28-03-2018 A21D_RS10945 6d4080b7966d028db911f163b6e568ea 227 SUPERFAMILY SSF52317 2 217 1.48E-72 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS09910 9e6a08edd613c11c991fe9a04474f788 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 262 2.6E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS09910 9e6a08edd613c11c991fe9a04474f788 266 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 18 265 2.7E-88 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A21D_RS09910 9e6a08edd613c11c991fe9a04474f788 266 SUPERFAMILY SSF161098 72 258 1.11E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS09910 9e6a08edd613c11c991fe9a04474f788 266 Gene3D G3DSA:1.10.3720.10 17 266 1.5E-29 T 28-03-2018 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 4.3E-36 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 Gene3D G3DSA:3.30.110.60 1 95 7.1E-29 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 1.1E-22 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 7.0E-34 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 SMART SM01103 2 85 8.2E-40 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A21D_RS15550 502802aca9100d679c9f44660eaae7da 96 SUPERFAMILY SSF75471 1 95 2.88E-30 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A21D_RS17955 0e1336052ccdf178305792d883b40c00 149 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 149 1.7E-49 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 A21D_RS17955 0e1336052ccdf178305792d883b40c00 149 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 97 146 1.4E-11 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A21D_RS17955 0e1336052ccdf178305792d883b40c00 149 Pfam PF00460 Flagella basal body rod protein 10 32 4.2E-8 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Gene3D G3DSA:3.40.50.300 61 243 1.4E-25 T 28-03-2018 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Gene3D G3DSA:3.40.50.300 2 60 1.2E-9 T 28-03-2018 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 SMART SM00382 29 151 7.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03765 9167ff467c87a86c6928277c200db931 527 SMART SM00382 297 458 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03765 9167ff467c87a86c6928277c200db931 527 ProSitePatterns PS00211 ABC transporters family signature. 385 399 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Pfam PF00005 ABC transporter 25 60 2.5E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Pfam PF00005 ABC transporter 289 413 3.4E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 SUPERFAMILY SSF52540 262 473 2.51E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Gene3D G3DSA:3.40.50.300 244 494 5.1E-46 T 28-03-2018 A21D_RS03765 9167ff467c87a86c6928277c200db931 527 Pfam PF12848 ABC transporter 147 206 8.2E-7 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS03765 9167ff467c87a86c6928277c200db931 527 SUPERFAMILY SSF52540 4 185 1.41E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17380 bb418ac100b42b31ead53a670e79426f 574 Gene3D G3DSA:3.30.420.10 5 159 9.3E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS17380 bb418ac100b42b31ead53a670e79426f 574 SUPERFAMILY SSF56672 230 569 7.23E-23 T 28-03-2018 A21D_RS17380 bb418ac100b42b31ead53a670e79426f 574 SUPERFAMILY SSF53098 19 153 1.73E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS17380 bb418ac100b42b31ead53a670e79426f 574 Gene3D G3DSA:3.90.1600.10 249 294 0.055 T 28-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17380 bb418ac100b42b31ead53a670e79426f 574 Gene3D G3DSA:3.90.1600.10 295 427 5.7E-14 T 28-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 SUPERFAMILY SSF55035 110 221 2.14E-32 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 Gene3D G3DSA:3.90.770.10 218 392 1.0E-38 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 Gene3D G3DSA:3.30.70.420 123 217 1.3E-33 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 SUPERFAMILY SSF56542 231 427 8.76E-105 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 SUPERFAMILY SSF56542 5 118 8.76E-105 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 14 387 1.8E-115 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 Gene3D G3DSA:3.90.770.10 3 122 5.1E-27 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 373 386 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A21D_RS05380 e9bd2625d14d1650fcad11cd11326108 429 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 1 387 3.4E-129 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 Pfam PF04439 Streptomycin adenylyltransferase 1 279 1.1E-113 T 28-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 PIRSF PIRSF000812 1 285 2.4E-102 T 28-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 Gene3D G3DSA:1.20.120.330 151 282 5.8E-44 T 28-03-2018 A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 SUPERFAMILY SSF81631 138 282 1.26E-46 T 28-03-2018 A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 Gene3D G3DSA:3.30.460.10 9 150 2.2E-43 T 28-03-2018 A21D_RS11285 730ffcdf9eb032aad1174410ed21f3a6 287 SUPERFAMILY SSF81301 1 134 1.46E-46 T 28-03-2018 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SUPERFAMILY SSF52172 2 137 4.41E-28 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SMART SM00862 147 226 4.6E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Pfam PF03704 Bacterial transcriptional activator domain 252 369 1.4E-9 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SUPERFAMILY SSF46894 136 225 5.39E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SMART SM01043 233 372 4.7E-4 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Gene3D G3DSA:3.40.50.2300 1 129 2.0E-26 T 28-03-2018 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 215 9.7E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SMART SM00448 1 112 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Pfam PF00072 Response regulator receiver domain 4 112 2.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 SUPERFAMILY SSF48452 254 371 3.49E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Gene3D G3DSA:1.10.10.10 130 229 5.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13755 d18a8280ce38a4f616d516896f551433 376 Gene3D G3DSA:1.25.40.10 288 375 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 Pfam PF02901 Pyruvate formate lyase-like 23 607 3.0E-208 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 ProSitePatterns PS00850 Glycine radical domain signature. 718 726 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 PIRSF PIRSF000379 5 748 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 9 747 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 SUPERFAMILY SSF51998 4 746 3.98E-287 T 28-03-2018 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 Gene3D G3DSA:3.20.70.20 1 748 2.1E-294 T 28-03-2018 A21D_RS04740 b5e97d8a7625531fb9a251aa03a2c2fe 748 Pfam PF01228 Glycine radical 623 729 2.9E-43 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 Gene3D G3DSA:3.40.50.720 136 294 1.6E-29 T 28-03-2018 A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 292 1.5E-45 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 Gene3D G3DSA:3.40.50.720 7 135 8.3E-28 T 28-03-2018 A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 39 319 8.4E-17 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 233 249 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 SUPERFAMILY SSF51735 111 293 1.7E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01695 bda29ea317bdb52b626f03a8c23832c7 341 SUPERFAMILY SSF52283 19 134 8.13E-33 T 28-03-2018 A21D_RS18515 04cced62d011d30ba8d6a45fc485f762 121 Gene3D G3DSA:1.20.5.10 106 121 0.015 T 28-03-2018 A21D_RS18515 04cced62d011d30ba8d6a45fc485f762 121 SUPERFAMILY SSF160755 1 116 5.1E-38 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS18515 04cced62d011d30ba8d6a45fc485f762 121 Gene3D G3DSA:3.30.310.100 1 105 1.7E-39 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS18515 04cced62d011d30ba8d6a45fc485f762 121 Pfam PF08868 YugN-like family 6 96 1.3E-13 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS17805 3c3f2951871df43035b2318acceea8f9 457 Pfam PF03961 Flagellar Assembly Protein A 8 451 1.9E-106 T 28-03-2018 IPR005646 Flagellar assembly protein A A21D_RS17805 3c3f2951871df43035b2318acceea8f9 457 Gene3D G3DSA:2.160.20.70 187 302 9.7E-11 T 28-03-2018 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SUPERFAMILY SSF68912 5 50 1.49E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Pfam PF07497 Rho termination factor, RNA-binding domain 55 127 6.0E-31 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Gene3D G3DSA:2.40.50.140 52 116 2.2E-27 T 28-03-2018 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 364 4.7E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SMART SM00382 169 356 6.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SUPERFAMILY SSF50249 52 127 5.14E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SMART SM00357 55 120 1.4E-18 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SMART SM00959 8 50 2.1E-15 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Pfam PF07498 Rho termination factor, N-terminal domain 9 50 8.2E-15 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 TIGRFAM TIGR00767 rho: transcription termination factor Rho 6 416 1.1E-197 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Gene3D G3DSA:3.40.50.300 117 368 3.5E-49 T 28-03-2018 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 213.794 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 SUPERFAMILY SSF52540 92 372 2.13E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04670 1a043a4e003a0e925cf5ba294436f242 427 Gene3D G3DSA:1.10.720.10 3 46 3.7E-14 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 Gene3D G3DSA:3.40.50.300 1 216 1.5E-60 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 Hamap MF_00551 Uridine kinase [udk]. 2 206 41.487 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 150 161 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 80 95 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 5 22 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 35 46 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 172 185 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 PRINTS PR00988 Uridine kinase signature 136 146 1.2E-38 T 28-03-2018 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 TIGRFAM TIGR00235 udk: uridine kinase 4 205 3.5E-90 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 SUPERFAMILY SSF52540 3 197 2.0E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15450 f174f910f599e196f151cd5dbb480723 216 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 5.8E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 Gene3D G3DSA:3.30.590.10 106 445 4.3E-129 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 SMART SM01230 106 355 9.6E-136 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 235 250 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 Gene3D G3DSA:3.10.20.70 3 105 1.5E-38 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 3.3E-139 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 SUPERFAMILY SSF54368 6 105 7.32E-35 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 SUPERFAMILY SSF55931 106 442 3.34E-128 T 28-03-2018 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 99 1.2E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS17495 6c8b2cc1200e06c9ba72f2bbca0d08f0 445 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 442 2.4E-181 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A21D_RS19345 bfa723ef70b8cc3f35186032ff6ed4af 237 SUPERFAMILY SSF53800 6 156 4.41E-17 T 28-03-2018 A21D_RS19345 bfa723ef70b8cc3f35186032ff6ed4af 237 Gene3D G3DSA:3.40.50.1400 125 212 0.011 T 28-03-2018 A21D_RS19345 bfa723ef70b8cc3f35186032ff6ed4af 237 Gene3D G3DSA:3.40.50.1400 1 124 5.0E-13 T 28-03-2018 A21D_RS19345 bfa723ef70b8cc3f35186032ff6ed4af 237 Pfam PF01903 CbiX 11 115 7.7E-12 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A21D_RS05350 a40340f1367aa2d16ac850a7ba711e58 257 SUPERFAMILY SSF64167 1 251 3.92E-71 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A21D_RS05350 a40340f1367aa2d16ac850a7ba711e58 257 Pfam PF01975 Survival protein SurE 3 182 7.1E-54 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A21D_RS05350 a40340f1367aa2d16ac850a7ba711e58 257 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 235 5.1E-61 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A21D_RS05350 a40340f1367aa2d16ac850a7ba711e58 257 Gene3D G3DSA:3.40.1210.10 1 256 4.1E-77 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A21D_RS05350 a40340f1367aa2d16ac850a7ba711e58 257 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 255 32.546 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 ProSitePatterns PS00221 MIP family signature. 65 73 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 Gene3D G3DSA:1.20.1080.10 4 241 6.9E-83 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 139 157 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 216 236 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 84 103 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 47 71 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 PRINTS PR00783 Major intrinsic protein family signature 169 191 1.0E-47 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 Pfam PF00230 Major intrinsic protein 6 233 4.9E-49 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 233 3.6E-61 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A21D_RS01290 239255f769df8ad445201edacc95d16d 277 SUPERFAMILY SSF81338 6 238 4.19E-71 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A21D_RS03395 bc9d892bb02bf78000bc0f7e38e29a62 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS03395 bc9d892bb02bf78000bc0f7e38e29a62 323 Gene3D G3DSA:1.10.10.60 4 47 6.4E-8 T 28-03-2018 A21D_RS03395 bc9d892bb02bf78000bc0f7e38e29a62 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS03395 bc9d892bb02bf78000bc0f7e38e29a62 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 SUPERFAMILY SSF52029 182 374 1.64E-84 T 28-03-2018 IPR027409 GroEL-like apical domain A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 Gene3D G3DSA:1.10.560.10 61 177 2.6E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 Hamap MF_00600 60 kDa chaperonin [groL]. 1 544 42.414 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.5E-104 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 SUPERFAMILY SSF48592 404 518 9.99E-81 T 28-03-2018 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 SUPERFAMILY SSF48592 5 133 9.99E-81 T 28-03-2018 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 Gene3D G3DSA:1.10.560.10 372 513 4.5E-29 T 28-03-2018 IPR027413 GroEL-like equatorial domain A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 SUPERFAMILY SSF54849 136 205 1.21E-26 T 28-03-2018 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.3E-257 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 Gene3D G3DSA:3.50.7.10 178 371 3.1E-99 T 28-03-2018 IPR027409 GroEL-like apical domain A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 PRINTS PR00298 60kDa chaperonin signature 396 417 1.0E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 PRINTS PR00298 60kDa chaperonin signature 348 373 1.0E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 PRINTS PR00298 60kDa chaperonin signature 82 109 1.0E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 PRINTS PR00298 60kDa chaperonin signature 26 52 1.0E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS10225 fbf8327e85755c9f9f03ecc40440f031 545 PRINTS PR00298 60kDa chaperonin signature 266 289 1.0E-71 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 29 289 1.6E-77 T 28-03-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 268 4.3E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 SMART SM00062 43 274 2.5E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 Gene3D G3DSA:3.40.190.10 22 139 8.4E-23 T 28-03-2018 A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 SUPERFAMILY SSF53850 39 268 5.62E-41 T 28-03-2018 A21D_RS02975 7643841203a45f51a4db841b273b9e29 293 Gene3D G3DSA:3.40.190.10 140 229 1.5E-15 T 28-03-2018 A21D_RS12475 1e378f2184500d434ecf0424aa6357ab 264 Gene3D G3DSA:3.40.50.300 1 262 2.1E-63 T 28-03-2018 A21D_RS12475 1e378f2184500d434ecf0424aa6357ab 264 Pfam PF00005 ABC transporter 25 163 1.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS12475 1e378f2184500d434ecf0424aa6357ab 264 SMART SM00382 33 212 2.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12475 1e378f2184500d434ecf0424aa6357ab 264 SUPERFAMILY SSF52540 2 230 6.79E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12475 1e378f2184500d434ecf0424aa6357ab 264 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 SUPERFAMILY SSF63520 57 164 1.24E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Pfam PF00874 PRD domain 180 272 3.8E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Pfam PF00874 PRD domain 73 161 4.3E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Gene3D G3DSA:1.10.1790.10 54 162 1.9E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Gene3D G3DSA:1.10.1790.10 163 276 1.0E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 SUPERFAMILY SSF50151 3 53 5.36E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 SMART SM01061 2 60 3.9E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Gene3D G3DSA:2.30.24.10 1 53 3.1E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 SUPERFAMILY SSF63520 169 273 4.97E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS10740 7ddcdc055a005bb5ad87d1d2d47409d6 279 Pfam PF03123 CAT RNA binding domain 3 56 9.4E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.5E-112 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.1E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 43.623 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 Gene3D G3DSA:3.40.50.10490 5 249 1.1E-105 T 28-03-2018 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 Pfam PF00318 Ribosomal protein S2 9 223 3.0E-101 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A21D_RS17790 5c97e014c57d7a6b4ef6805031624a56 249 SUPERFAMILY SSF52313 6 228 1.44E-99 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain A21D_RS10065 9bd556465ceaed14978926cb58e28275 197 SMART SM00331 3 193 7.7E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10065 9bd556465ceaed14978926cb58e28275 197 Gene3D G3DSA:3.60.40.10 1 192 1.0E-13 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10065 9bd556465ceaed14978926cb58e28275 197 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 32 192 2.2E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10065 9bd556465ceaed14978926cb58e28275 197 SUPERFAMILY SSF81606 5 192 8.63E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Gene3D G3DSA:3.40.1110.10 509 610 1.4E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Gene3D G3DSA:3.40.50.1000 611 759 9.5E-43 T 28-03-2018 IPR023214 HAD-like domain A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Gene3D G3DSA:1.20.1110.10 258 508 2.4E-49 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Gene3D G3DSA:3.30.70.100 3 71 2.0E-21 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF81665 259 295 1.03E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF81665 392 487 1.03E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF81665 736 767 1.03E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 70 2.4E-12 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF55008 71 139 2.88E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Pfam PF00122 E1-E2 ATPase 292 472 1.4E-57 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 88 102 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 209 228 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 476 491 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 117 137 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 414 428 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 261 280 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00943 Copper-transporting ATPase signature 664 681 1.7E-14 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Pfam PF00403 Heavy-metal-associated domain 9 67 9.8E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Pfam PF00403 Heavy-metal-associated domain 76 136 8.2E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 39 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 495 501 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 224 789 5.9E-201 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF56784 492 511 1.6E-64 T 28-03-2018 IPR023214 HAD-like domain A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF56784 545 787 1.6E-64 T 28-03-2018 IPR023214 HAD-like domain A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 710 722 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 507 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 341 355 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 687 706 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 623 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 644 4.5E-28 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF55008 5 70 2.23E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 264 771 1.4E-97 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 205 790 7.8E-190 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Gene3D G3DSA:3.30.70.100 72 159 1.7E-23 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 701 6.8E-45 T 28-03-2018 A21D_RS02800 b677dac1c0292a507de245ebcb97c2e5 794 SUPERFAMILY SSF81653 295 391 1.28E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 TIGRFAM TIGR00433 bioB: biotin synthase 28 319 1.1E-114 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 Gene3D G3DSA:3.20.20.70 14 323 9.7E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 SMART SM00729 54 259 1.3E-28 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 SMART SM00876 230 320 2.7E-30 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 PIRSF PIRSF001619 2 326 1.7E-116 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 SUPERFAMILY SSF102114 14 320 1.31E-67 T 28-03-2018 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 230 319 1.7E-13 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 Hamap MF_01694 Biotin synthase [bioB]. 14 321 38.391 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A21D_RS07000 571e0d1668b4d371b7cf38466875870d 329 Pfam PF04055 Radical SAM superfamily 62 218 4.3E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS01765 e77dc74a45e48cd97ae1ca1ce35f69f4 419 Pfam PF05977 Transmembrane secretion effector 5 403 2.1E-28 T 28-03-2018 IPR010290 Transmembrane secretion effector A21D_RS01765 e77dc74a45e48cd97ae1ca1ce35f69f4 419 Gene3D G3DSA:1.20.1250.20 211 406 1.4E-9 T 28-03-2018 A21D_RS01765 e77dc74a45e48cd97ae1ca1ce35f69f4 419 Gene3D G3DSA:1.20.1250.20 1 203 6.9E-19 T 28-03-2018 A21D_RS01765 e77dc74a45e48cd97ae1ca1ce35f69f4 419 SUPERFAMILY SSF103473 7 399 3.14E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SUPERFAMILY SSF47384 343 427 1.96E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SUPERFAMILY SSF55785 234 351 5.08E-6 T 28-03-2018 IPR000014 PAS domain A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Gene3D G3DSA:1.10.287.130 365 420 5.0E-18 T 28-03-2018 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SMART SM00304 188 240 1.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 426 1.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 3.9E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 3.9E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 3.9E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 3.9E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Gene3D G3DSA:3.30.450.20 244 364 5.5E-10 T 28-03-2018 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SUPERFAMILY SSF55874 415 584 1.96E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Gene3D G3DSA:3.30.565.10 421 584 5.3E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SUPERFAMILY SSF158472 189 236 1.7E-9 T 28-03-2018 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SMART SM00388 359 426 2.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Pfam PF00672 HAMP domain 189 235 5.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Gene3D G3DSA:3.30.450.20 31 162 2.9E-6 T 28-03-2018 A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 583 1.6E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16445 c56984be48e706bbdda218cb1aa84f93 585 SMART SM00387 472 585 1.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13910 bf959458f3c122ec64a5eb6f5c369ec9 311 Gene3D G3DSA:3.90.1200.10 79 191 0.016 T 28-03-2018 A21D_RS13910 bf959458f3c122ec64a5eb6f5c369ec9 311 Gene3D G3DSA:3.90.1200.10 198 293 1.9E-5 T 28-03-2018 A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 90 3.6E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 Gene3D G3DSA:1.10.150.130 2 110 3.1E-25 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 300 52.84 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 SUPERFAMILY SSF56349 4 294 1.12E-57 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 Gene3D G3DSA:1.10.443.10 112 294 3.4E-45 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 10 301 9.9E-107 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 A21D_RS17985 c63ec458ad83a24021a5c638378b3c83 302 Pfam PF00589 Phage integrase family 113 286 1.5E-50 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 SMART SM00382 42 234 5.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 1.1E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 Gene3D G3DSA:3.40.50.300 3 335 5.0E-83 T 28-03-2018 A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 323 1.0E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 SUPERFAMILY SSF52540 6 256 1.94E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10630 3faf1c165c1cea64d3c6a50ecbb5b6e1 336 Pfam PF00005 ABC transporter 34 184 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05080 ebd93cc4b1e55ea5743fa6b3a2c7495b 251 SUPERFAMILY SSF53335 12 228 4.14E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS05080 ebd93cc4b1e55ea5743fa6b3a2c7495b 251 Pfam PF08241 Methyltransferase domain 54 149 1.4E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS05080 ebd93cc4b1e55ea5743fa6b3a2c7495b 251 Gene3D G3DSA:3.40.50.150 2 251 6.3E-37 T 28-03-2018 A21D_RS15435 d05f7d35a8bc9fcaa6c2737d50cb343d 93 Pfam PF06949 Protein of unknown function (DUF1292) 14 88 2.4E-20 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 A21D_RS15435 d05f7d35a8bc9fcaa6c2737d50cb343d 93 Hamap MF_01448 UPF0473 protein . 5 89 18.799 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 Gene3D G3DSA:3.40.50.2300 181 338 2.2E-40 T 28-03-2018 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 SUPERFAMILY SSF53822 60 336 3.43E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 SUPERFAMILY SSF47413 1 59 3.26E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 Gene3D G3DSA:3.40.50.2300 55 180 1.1E-28 T 28-03-2018 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 SMART SM00354 1 71 6.1E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 Gene3D G3DSA:1.10.260.40 2 54 4.3E-23 T 28-03-2018 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.6E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS01090 da5a6e194ce34c9f3e5fc46c91134eda 338 Pfam PF13377 Periplasmic binding protein-like domain 175 335 9.6E-33 T 28-03-2018 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 SUPERFAMILY SSF53901 270 390 9.82E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 Pfam PF02803 Thiolase, C-terminal domain 270 389 9.3E-49 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 Gene3D G3DSA:3.40.47.10 144 268 4.0E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 Gene3D G3DSA:3.40.47.10 1 132 2.9E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 Gene3D G3DSA:3.40.47.10 269 388 3.5E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 4.8E-138 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.6E-73 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 PIRSF PIRSF000429 1 391 1.6E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS00285 aaaa6154b1913c8b5808a20b290ffbcf 391 SUPERFAMILY SSF53901 3 268 3.52E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 SUPERFAMILY SSF53271 246 459 1.1E-68 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 454 45.977 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 Gene3D G3DSA:3.40.50.2020 224 434 2.7E-35 T 28-03-2018 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 PIRSF PIRSF000485 8 469 2.7E-180 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 Pfam PF00156 Phosphoribosyl transferase domain 276 381 1.9E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 Pfam PF13522 Glutamine amidotransferase domain 72 204 3.0E-24 T 28-03-2018 A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 Gene3D G3DSA:3.60.20.10 11 223 5.0E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 SUPERFAMILY SSF56235 12 238 2.57E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS10955 3e685dcca596ba9a5c2508076ef14ad4 470 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 455 4.8E-165 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 SMART SM00838 397 482 6.3E-8 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 2.0E-289 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 146 2.9E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Pfam PF00679 Elongation factor G C-terminus 399 477 8.4E-26 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 SUPERFAMILY SSF52540 3 209 1.4E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:2.40.50.250 485 575 5.4E-37 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:3.40.50.300 70 195 1.3E-30 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 SUPERFAMILY SSF50447 154 301 1.68E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Pfam PF03144 Elongation factor Tu domain 2 221 291 1.6E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:3.30.70.240 403 483 9.7E-21 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 SUPERFAMILY SSF54980 400 515 4.8E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:3.40.50.300 1 69 2.8E-9 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:3.30.70.870 305 402 5.3E-33 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 2.2E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 SUPERFAMILY SSF54980 304 389 3.6E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 Gene3D G3DSA:2.40.30.10 196 304 1.9E-21 T 28-03-2018 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS09815 7f4462dd2f6056c81c85d5d9bfd95960 606 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS07705 a0a3532ef1cca06ee98c01cf48344175 73 Gene3D G3DSA:2.30.30.90 1 73 4.3E-18 T 28-03-2018 A21D_RS07705 a0a3532ef1cca06ee98c01cf48344175 73 SUPERFAMILY SSF50037 3 72 2.35E-17 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal A21D_RS07705 a0a3532ef1cca06ee98c01cf48344175 73 SMART SM00899 1 73 2.2E-17 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A21D_RS07705 a0a3532ef1cca06ee98c01cf48344175 73 Pfam PF04023 FeoA domain 1 72 8.3E-18 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A21D_RS12875 70811bd28159ca821791187e442c7324 673 ProSitePatterns PS00211 ABC transporters family signature. 568 582 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS12875 70811bd28159ca821791187e442c7324 673 Pfam PF00664 ABC transporter transmembrane region 149 387 5.7E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS12875 70811bd28159ca821791187e442c7324 673 SUPERFAMILY SSF90123 141 417 1.7E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS12875 70811bd28159ca821791187e442c7324 673 SUPERFAMILY SSF90123 4 44 1.7E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS12875 70811bd28159ca821791187e442c7324 673 Gene3D G3DSA:1.20.1560.10 2 415 2.8E-63 T 28-03-2018 A21D_RS12875 70811bd28159ca821791187e442c7324 673 SMART SM00382 456 648 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12875 70811bd28159ca821791187e442c7324 673 SUPERFAMILY SSF52540 425 666 1.3E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12875 70811bd28159ca821791187e442c7324 673 Gene3D G3DSA:3.40.50.300 416 672 1.3E-66 T 28-03-2018 A21D_RS12875 70811bd28159ca821791187e442c7324 673 Pfam PF00005 ABC transporter 447 596 1.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.6E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.6E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.5E-46 T 28-03-2018 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 SMART SM00382 37 179 1.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 Gene3D G3DSA:3.40.50.300 15 166 7.6E-40 T 28-03-2018 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 357 4.5E-142 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 Gene3D G3DSA:1.20.272.10 243 362 1.1E-16 T 28-03-2018 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 SUPERFAMILY SSF48019 244 358 4.42E-20 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 Gene3D G3DSA:1.10.8.60 167 242 6.3E-22 T 28-03-2018 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 358 4.8E-9 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A21D_RS06900 b233670c8ab6d62c10af0d0e969ade29 562 SUPERFAMILY SSF52540 31 222 5.48E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 93 148 4.0E-11 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 Pfam PF01316 Arginine repressor, DNA binding domain 1 64 3.1E-17 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 Gene3D G3DSA:3.30.1360.40 77 149 9.8E-20 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 Pfam PF02863 Arginine repressor, C-terminal domain 83 149 2.7E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 Gene3D G3DSA:1.10.10.10 3 65 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 Hamap MF_00173 Arginine repressor [argR]. 1 156 44.54 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 SUPERFAMILY SSF55252 83 149 2.88E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 PRINTS PR01467 Bacterial arginine repressor signature 121 136 2.2E-13 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.2E-13 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 PRINTS PR01467 Bacterial arginine repressor signature 91 104 2.2E-13 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.2E-13 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS07965 2d74fba4655372517a74ce9677eff0a9 162 SUPERFAMILY SSF46785 3 72 1.72E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16575 43a133246e4dd8deaa1236e6838ec475 492 SUPERFAMILY SSF52540 19 238 8.74E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16575 43a133246e4dd8deaa1236e6838ec475 492 PIRSF PIRSF007466 1 492 2.0E-254 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A21D_RS16575 43a133246e4dd8deaa1236e6838ec475 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 2.4E-253 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A21D_RS16575 43a133246e4dd8deaa1236e6838ec475 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 5.7E-224 T 28-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A21D_RS16575 43a133246e4dd8deaa1236e6838ec475 492 Gene3D G3DSA:3.40.50.300 9 481 8.7E-14 T 28-03-2018 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 SUPERFAMILY SSF51735 172 362 2.54E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 Gene3D G3DSA:3.40.50.720 193 345 2.3E-21 T 28-03-2018 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 SUPERFAMILY SSF50129 4 200 3.74E-58 T 28-03-2018 IPR011032 GroES-like A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 3 402 1.1E-226 T 28-03-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 Gene3D G3DSA:3.90.180.10 5 192 6.1E-39 T 28-03-2018 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 3.8E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A21D_RS19515 f2b241fe4ffb2e4a96e761f8ef42722e 405 Pfam PF00107 Zinc-binding dehydrogenase 206 275 1.5E-7 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 Pfam PF07702 UTRA domain 103 240 3.7E-37 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 Gene3D G3DSA:3.40.1410.10 80 246 6.0E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 2.8E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 SMART SM00345 21 80 2.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 8.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 8.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 Gene3D G3DSA:1.10.10.10 4 79 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 SMART SM00866 101 240 5.9E-36 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 SUPERFAMILY SSF64288 68 245 1.88E-49 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS04115 a9c6a11ca55271dbb35b8f3f43cdb3d2 246 SUPERFAMILY SSF46785 10 94 2.94E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.198 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Gene3D G3DSA:3.10.28.10 112 219 4.3E-21 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 2.5E-129 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 SUPERFAMILY SSF55608 120 221 1.19E-20 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Pfam PF02650 WhiA C-terminal HTH domain 220 303 2.8E-34 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Gene3D G3DSA:3.10.28.10 13 94 7.3E-13 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 6.3E-36 T 28-03-2018 A21D_RS00650 dbd8dbd8ff17498e3fce41666aa04975 314 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 4.5E-35 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 120 2.6E-25 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 Pfam PF08282 haloacid dehalogenase-like hydrolase 131 241 4.6E-32 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 ProSitePatterns PS01228 Hypothetical cof family signature 1. 9 20 - T 28-03-2018 A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 214 4.8E-28 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 Gene3D G3DSA:3.40.50.1000 1 246 2.4E-46 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 ProSitePatterns PS01229 Hypothetical cof family signature 2. 195 217 - T 28-03-2018 A21D_RS00970 6cf53b93e75ee047afcea57942c182d4 246 SUPERFAMILY SSF56784 3 244 4.6E-68 T 28-03-2018 IPR023214 HAD-like domain A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.515 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 SUPERFAMILY SSF56047 2 132 1.83E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 Gene3D G3DSA:3.30.1370.30 1 67 1.4E-27 T 28-03-2018 A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 Pfam PF00410 Ribosomal protein S8 5 132 2.9E-55 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 Gene3D G3DSA:3.30.1490.10 69 130 1.5E-23 T 28-03-2018 A21D_RS06305 a333f990752632dcf6b58fa63bc36c0e 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 TIGRFAM TIGR02415 23BDH: acetoin reductases 3 257 9.1E-109 T 28-03-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 Gene3D G3DSA:3.40.50.720 40 257 4.9E-59 T 28-03-2018 A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 Gene3D G3DSA:3.40.50.720 1 39 6.0E-7 T 28-03-2018 A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 Pfam PF00106 short chain dehydrogenase 3 196 1.6E-57 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS04930 a23d7d042cc2b0c5e8869fff8b529415 257 SUPERFAMILY SSF51735 3 255 9.39E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 Gene3D G3DSA:3.30.479.20 158 291 1.6E-51 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 SUPERFAMILY SSF54713 152 293 4.71E-52 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 Pfam PF00889 Elongation factor TS 70 275 1.1E-74 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 79.767 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 294 9.6E-116 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 Gene3D G3DSA:3.30.479.20 57 157 2.2E-23 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 Gene3D G3DSA:1.10.8.10 1 55 3.1E-24 T 28-03-2018 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 SUPERFAMILY SSF54713 55 145 1.41E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS17785 df7ea6fa3051a9ea04aca60cafffc6f9 294 SUPERFAMILY SSF46934 1 55 5.11E-20 T 28-03-2018 IPR009060 UBA-like GO:0005515 A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 SUPERFAMILY SSF46785 6 118 7.26E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 Pfam PF01047 MarR family 13 70 5.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 116 5.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 5.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 62 5.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 Gene3D G3DSA:1.10.10.10 1 122 2.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09945 6d4b371b85c116b7def1514faa0b6798 123 SMART SM00347 6 106 2.5E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 7 510 4.0E-216 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 300 1.9E-86 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 PIRSF PIRSF001492 1 511 7.7E-204 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 Pfam PF01676 Metalloenzyme superfamily 7 500 5.0E-74 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 511 49.362 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 Gene3D G3DSA:3.40.720.10 306 492 5.1E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 Gene3D G3DSA:3.40.1450.10 78 305 8.1E-100 T 28-03-2018 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 SUPERFAMILY SSF53649 316 510 3.66E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 SUPERFAMILY SSF53649 8 78 3.66E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS00510 df37020c03dbc3868979f6484819abf8 511 SUPERFAMILY SSF64158 78 311 7.59E-94 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 Gene3D G3DSA:3.90.110.10 147 314 1.9E-40 T 28-03-2018 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 SUPERFAMILY SSF51735 4 147 1.01E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 315 39.742 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PIRSF PIRSF000102 3 316 1.5E-97 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 5.1E-25 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 2.0E-107 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 2.9E-35 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 SUPERFAMILY SSF56327 146 313 9.37E-49 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 Gene3D G3DSA:3.40.50.720 7 146 1.6E-30 T 28-03-2018 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 8.6E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 8.6E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 8.6E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 8.6E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 8.6E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS13740 31a62173e42267d93e3dea05f19706ed 316 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 SUPERFAMILY SSF51604 138 426 3.4E-132 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 423 7.6E-139 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 SUPERFAMILY SSF54826 3 138 3.98E-59 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 161 174 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 363 380 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 37 51 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 311 322 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 334 348 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PRINTS PR00148 Enolase signature 107 123 8.9E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.3E-217 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 Gene3D G3DSA:3.30.390.10 3 127 4.6E-56 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 SMART SM01193 4 134 2.1E-97 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 Hamap MF_00318 Enolase [eno]. 2 411 45.758 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 Gene3D G3DSA:3.20.20.120 128 428 3.4E-107 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 PIRSF PIRSF001400 1 425 1.6E-194 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 SMART SM01192 139 425 1.2E-228 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 Pfam PF03952 Enolase, N-terminal domain 4 134 3.8E-62 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A21D_RS00505 d93c299aec5e6412bac1b8d11394ef19 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS02400 d6040bb6d3adb6224efe5123ea311bb9 417 Pfam PF13520 Amino acid permease 8 392 4.2E-39 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS02400 d6040bb6d3adb6224efe5123ea311bb9 417 PIRSF PIRSF006060 1 416 1.7E-59 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS12095 5b33196833d056a9f0f16c4fc5e037f6 133 Pfam PF13273 Protein of unknown function (DUF4064) 2 101 1.0E-14 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 A21D_RS02670 172f737d029579fdaeea713d1f35aac5 255 Gene3D G3DSA:3.20.20.140 1 247 7.3E-21 T 28-03-2018 A21D_RS02670 172f737d029579fdaeea713d1f35aac5 255 SUPERFAMILY SSF89550 2 199 3.34E-13 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS02670 172f737d029579fdaeea713d1f35aac5 255 PIRSF PIRSF016557 1 255 1.2E-103 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 Gene3D G3DSA:1.25.40.10 207 422 2.0E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 Gene3D G3DSA:1.25.40.10 67 198 4.0E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 Gene3D G3DSA:1.10.260.40 2 66 2.2E-9 T 28-03-2018 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SUPERFAMILY SSF47413 2 61 7.32E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 Pfam PF01381 Helix-turn-helix 8 59 1.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SUPERFAMILY SSF48452 150 368 3.34E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SMART SM00028 386 419 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SMART SM00028 266 299 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SMART SM00028 226 259 52.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SMART SM00028 145 178 43.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS07570 efb668405f510631d60f4aebbbbb5e6a 422 SMART SM00530 7 61 1.6E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 189 4.6E-38 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 SUPERFAMILY SSF81296 29 193 2.24E-58 T 28-03-2018 IPR014756 Immunoglobulin E-set A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 Gene3D G3DSA:2.10.10.20 199 256 7.3E-16 T 28-03-2018 A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 Gene3D G3DSA:2.70.50.50 29 192 1.4E-53 T 28-03-2018 A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 SMART SM00495 212 254 7.6E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 Pfam PF02839 Carbohydrate binding domain 229 251 1.8E-5 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A21D_RS02710 5d29c4ec4e0fbff6ba5f21dbdb675fad 278 SUPERFAMILY SSF51055 209 256 1.7E-16 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A21D_RS05865 132bd87edc4a568c299b6d577815dc48 331 SUPERFAMILY SSF81345 5 327 2.62E-84 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS05865 132bd87edc4a568c299b6d577815dc48 331 Gene3D G3DSA:1.10.3470.10 5 330 5.1E-71 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS05865 132bd87edc4a568c299b6d577815dc48 331 Pfam PF01032 FecCD transport family 20 327 2.2E-96 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 493 8.0E-128 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 Gene3D G3DSA:1.20.1250.20 287 491 3.4E-9 T 28-03-2018 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 SUPERFAMILY SSF103473 280 488 6.15E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03415 b127c22af90114b1e317582baf987a37 497 SUPERFAMILY SSF103473 18 214 6.15E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03415 b127c22af90114b1e317582baf987a37 497 Gene3D G3DSA:1.20.1250.20 11 214 4.1E-21 T 28-03-2018 A21D_RS03415 b127c22af90114b1e317582baf987a37 497 Pfam PF00854 POT family 96 464 1.6E-79 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 A21D_RS14820 c2cd4e1655b519b5e3f8b4081c5894fb 147 SUPERFAMILY SSF111126 21 130 1.62E-21 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain A21D_RS14820 c2cd4e1655b519b5e3f8b4081c5894fb 147 Gene3D G3DSA:3.30.1380.20 2 132 3.1E-18 T 28-03-2018 A21D_RS14820 c2cd4e1655b519b5e3f8b4081c5894fb 147 Pfam PF10702 Protein of unknown function (DUF2507) 23 141 2.6E-37 T 28-03-2018 IPR019642 Protein of unknown function DUF2507 A21D_RS09485 f65a32207d92f1eb46015097332c891f 155 SUPERFAMILY SSF55804 3 148 4.97E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS09485 f65a32207d92f1eb46015097332c891f 155 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 148 3.0E-36 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS09485 f65a32207d92f1eb46015097332c891f 155 Gene3D G3DSA:3.40.930.10 1 150 6.1E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12365 5fe765be52aaa14b8acd88f8512b23f3 472 Pfam PF03606 C4-dicarboxylate anaerobic carrier 17 465 1.8E-93 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A21D_RS01280 b888a77e5846f8eeb9c1a94035158747 331 Gene3D G3DSA:3.40.50.10440 11 184 6.6E-74 T 28-03-2018 A21D_RS01280 b888a77e5846f8eeb9c1a94035158747 331 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 1.9E-157 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 A21D_RS01280 b888a77e5846f8eeb9c1a94035158747 331 SUPERFAMILY SSF82549 11 330 5.49E-128 T 28-03-2018 A21D_RS01280 b888a77e5846f8eeb9c1a94035158747 331 Gene3D G3DSA:3.30.1180.20 185 331 2.3E-53 T 28-03-2018 A21D_RS01280 b888a77e5846f8eeb9c1a94035158747 331 Pfam PF02733 Dak1 domain 17 328 5.1E-134 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS12140 6d52d11214372c084997b0d528160148 593 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 20 186 9.1E-48 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS12140 6d52d11214372c084997b0d528160148 593 SUPERFAMILY SSF52518 18 189 3.31E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12140 6d52d11214372c084997b0d528160148 593 Gene3D G3DSA:3.40.50.1220 203 368 1.2E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS12140 6d52d11214372c084997b0d528160148 593 Gene3D G3DSA:3.40.50.970 14 202 5.4E-46 T 28-03-2018 A21D_RS12140 6d52d11214372c084997b0d528160148 593 SUPERFAMILY SSF52467 201 376 1.77E-43 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS12140 6d52d11214372c084997b0d528160148 593 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 19 583 1.4E-247 T 28-03-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 A21D_RS12140 6d52d11214372c084997b0d528160148 593 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 557 2.4E-35 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS12140 6d52d11214372c084997b0d528160148 593 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 447 466 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A21D_RS12140 6d52d11214372c084997b0d528160148 593 SUPERFAMILY SSF52518 386 570 1.79E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12140 6d52d11214372c084997b0d528160148 593 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 344 1.6E-37 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A21D_RS12140 6d52d11214372c084997b0d528160148 593 Gene3D G3DSA:3.40.50.970 369 571 4.6E-37 T 28-03-2018 A21D_RS02425 df4e5e8cf56dbd77c9b8dd83ac9ed3a7 362 Gene3D G3DSA:3.40.50.10490 210 356 4.1E-22 T 28-03-2018 A21D_RS02425 df4e5e8cf56dbd77c9b8dd83ac9ed3a7 362 Gene3D G3DSA:3.40.50.10490 1 209 1.1E-34 T 28-03-2018 A21D_RS02425 df4e5e8cf56dbd77c9b8dd83ac9ed3a7 362 SUPERFAMILY SSF53697 10 348 2.32E-54 T 28-03-2018 A21D_RS02425 df4e5e8cf56dbd77c9b8dd83ac9ed3a7 362 Pfam PF01380 SIS domain 228 338 6.5E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS02425 df4e5e8cf56dbd77c9b8dd83ac9ed3a7 362 Pfam PF01380 SIS domain 41 166 8.3E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 SUPERFAMILY SSF52540 295 534 2.08E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Gene3D G3DSA:3.30.450.40 30 212 0.0016 T 28-03-2018 IPR029016 GAF domain-like A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Gene3D G3DSA:1.10.10.60 565 600 2.5E-11 T 28-03-2018 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Pfam PF00158 Sigma-54 interaction domain 296 462 1.3E-66 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 SUPERFAMILY SSF46689 504 600 1.46E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Gene3D G3DSA:3.40.50.300 290 467 3.7E-25 T 28-03-2018 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 SUPERFAMILY SSF55781 124 214 3.64E-5 T 28-03-2018 IPR029016 GAF domain-like A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Pfam PF02954 Bacterial regulatory protein, Fis family 560 598 4.4E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Pfam PF01590 GAF domain 115 203 3.6E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 Gene3D G3DSA:1.10.8.60 468 564 3.8E-8 T 28-03-2018 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 564 581 1.2E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 581 600 1.2E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 382 397 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A21D_RS19545 350e7043d07785cfdac632caed9af5ca 600 SMART SM00382 315 459 5.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 Gene3D G3DSA:1.20.1090.10 197 402 4.1E-56 T 28-03-2018 A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 273 293 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 SUPERFAMILY SSF56796 12 395 2.49E-118 T 28-03-2018 A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 Gene3D G3DSA:3.40.50.1970 19 196 2.9E-46 T 28-03-2018 A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 186 214 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS10760 eec2f64d65223c7cfa7248c1995a5952 402 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 386 1.2E-115 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 ProSitePatterns PS00321 recA signature. 212 220 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 Pfam PF00154 recA bacterial DNA recombination protein 6 267 2.8E-147 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 Hamap MF_00268 Protein RecA [recA]. 4 328 53.156 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 SUPERFAMILY SSF52540 3 266 4.22E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 SMART SM00382 56 227 4.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 Gene3D G3DSA:3.40.50.300 25 267 3.2E-49 T 28-03-2018 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 164 193 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 209 237 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 126 155 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 242 271 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 92 121 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 PRINTS PR00142 RecA protein signature 296 313 6.4E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 SUPERFAMILY SSF54752 267 325 5.23E-21 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 Gene3D G3DSA:3.30.250.10 268 325 1.3E-25 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A21D_RS17575 a6facac3c9133c2ea0b7ce76d8186745 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 322 2.3E-175 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A21D_RS14415 a1224155e1faa22cd3a08bdef42f8b16 379 PIRSF PIRSF005572 1 378 1.7E-112 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A21D_RS14415 a1224155e1faa22cd3a08bdef42f8b16 379 SUPERFAMILY SSF53383 1 373 3.06E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS14415 a1224155e1faa22cd3a08bdef42f8b16 379 Gene3D G3DSA:3.90.1150.10 242 369 2.3E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS14415 a1224155e1faa22cd3a08bdef42f8b16 379 Pfam PF00266 Aminotransferase class-V 2 363 3.4E-73 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS14415 a1224155e1faa22cd3a08bdef42f8b16 379 Gene3D G3DSA:3.40.640.10 11 241 1.3E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS03640 0fa13978984ece5fd71e11953b0969f7 262 SUPERFAMILY SSF48576 2 247 4.46E-42 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS03640 0fa13978984ece5fd71e11953b0969f7 262 Pfam PF00494 Squalene/phytoene synthase 4 196 8.0E-24 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 A21D_RS03640 0fa13978984ece5fd71e11953b0969f7 262 Gene3D G3DSA:1.10.600.10 1 258 8.0E-48 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 Pfam PF00367 phosphotransferase system, EIIB 431 462 1.4E-10 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 537 657 1.5E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 SUPERFAMILY SSF55604 427 500 4.84E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 402 486 5.4E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 SUPERFAMILY SSF51261 530 679 7.85E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 502 2.4E-256 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 Pfam PF02378 Phosphotransferase system, EIIC 13 342 3.6E-95 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 599 611 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 536 659 1.1E-50 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 Gene3D G3DSA:2.70.70.10 523 682 8.3E-59 T 28-03-2018 A21D_RS12390 01db3352162df14dbf45925dbeec3cc0 682 Gene3D G3DSA:3.30.1360.60 425 500 2.5E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 41.37 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 Gene3D G3DSA:3.20.20.70 1 252 7.4E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 SUPERFAMILY SSF51351 1 249 7.07E-96 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 4.7E-63 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00515 60c4f01c2adc68e88aaafb816842d81c 252 Pfam PF00121 Triosephosphate isomerase 4 247 7.2E-98 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 Pfam PF02254 TrkA-N domain 5 120 1.3E-28 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 Gene3D G3DSA:3.40.50.720 3 135 9.8E-23 T 28-03-2018 A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 SUPERFAMILY SSF51735 4 134 1.97E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 SUPERFAMILY SSF116726 131 216 2.35E-22 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 Pfam PF02080 TrkA-C domain 150 215 4.9E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS18695 2e155c373750846bef21f6ba07b76c55 221 Gene3D G3DSA:3.30.70.1450 136 218 1.2E-21 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS19525 a3000ed5bc56810aa93cd59fe122a022 409 Gene3D G3DSA:3.90.350.10 145 311 6.8E-18 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS19525 a3000ed5bc56810aa93cd59fe122a022 409 Pfam PF01609 Transposase DDE domain 126 329 1.2E-20 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS19525 a3000ed5bc56810aa93cd59fe122a022 409 SUPERFAMILY SSF53098 81 342 5.31E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS19525 a3000ed5bc56810aa93cd59fe122a022 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 77 3.7E-11 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS08695 a3000ed5bc56810aa93cd59fe122a022 409 Gene3D G3DSA:3.90.350.10 145 311 6.8E-18 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS08695 a3000ed5bc56810aa93cd59fe122a022 409 Pfam PF01609 Transposase DDE domain 126 329 1.2E-20 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS08695 a3000ed5bc56810aa93cd59fe122a022 409 SUPERFAMILY SSF53098 81 342 5.31E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS08695 a3000ed5bc56810aa93cd59fe122a022 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 77 3.7E-11 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 Gene3D G3DSA:3.20.20.70 1 293 1.5E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 SUPERFAMILY SSF51569 3 288 2.93E-98 T 28-03-2018 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 2.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 2.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 2.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 2.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 286 2.8E-109 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 5.3E-105 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 61.335 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 SMART SM01130 2 290 7.7E-127 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 PIRSF PIRSF001365 1 293 2.2E-94 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS12230 a8557e7f27a0aa127911ae691b2aaf8a 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 SUPERFAMILY SSF55120 73 296 3.5E-81 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 Gene3D G3DSA:3.30.2350.10 79 303 1.4E-77 T 28-03-2018 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 Pfam PF01479 S4 domain 16 61 1.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 Gene3D G3DSA:3.10.290.10 2 72 5.7E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 SUPERFAMILY SSF55174 14 101 3.03E-13 T 28-03-2018 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 SMART SM00363 15 79 8.5E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 298 1.8E-101 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 Pfam PF00849 RNA pseudouridylate synthase 88 241 7.5E-39 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS18305 de7c63ba8a9cebaa2337cddf68eb0032 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SUPERFAMILY SSF55874 877 1015 3.8E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SMART SM00387 914 1017 2.8E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SMART SM00387 544 654 4.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF06580 Histidine kinase 821 900 2.2E-21 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SUPERFAMILY SSF55874 488 653 2.88E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 614 632 5.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 651 5.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 594 5.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 598 608 5.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Gene3D G3DSA:3.30.565.10 502 663 2.5E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SUPERFAMILY SSF47384 417 497 6.67E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SMART SM00388 430 498 7.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF07695 7TM diverse intracellular signalling 225 408 3.7E-9 T 28-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Gene3D G3DSA:3.30.565.10 884 1017 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SUPERFAMILY SSF49785 56 202 3.19E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 545 652 1.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 919 1016 5.3E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SUPERFAMILY SSF52172 687 817 5.27E-36 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Gene3D G3DSA:3.40.50.2300 683 883 1.3E-37 T 28-03-2018 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Gene3D G3DSA:1.10.287.130 421 494 5.7E-11 T 28-03-2018 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF00072 Response regulator receiver domain 694 804 9.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 SMART SM00448 692 804 2.0E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Gene3D G3DSA:2.60.120.260 50 209 4.3E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS13750 b3e9a1b6c763967bc0238365536f78f6 1017 Pfam PF00512 His Kinase A (phospho-acceptor) domain 432 497 9.6E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS02175 725da5a830ec2154bc04955451d7937c 125 Pfam PF01381 Helix-turn-helix 11 62 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02175 725da5a830ec2154bc04955451d7937c 125 Gene3D G3DSA:1.10.3100.10 2 123 1.7E-22 T 28-03-2018 IPR027910 YdiL-like domain A21D_RS02175 725da5a830ec2154bc04955451d7937c 125 SMART SM00530 7 62 2.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02175 725da5a830ec2154bc04955451d7937c 125 SUPERFAMILY SSF47413 2 70 1.42E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 Gene3D G3DSA:3.40.50.300 1 256 1.1E-74 T 28-03-2018 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 SUPERFAMILY SSF55021 249 338 4.81E-22 T 28-03-2018 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 SMART SM00382 30 217 2.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 SMART SM00930 263 338 8.0E-26 T 28-03-2018 IPR018449 NIL domain A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 Pfam PF00005 ABC transporter 21 169 7.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 Gene3D G3DSA:3.30.70.260 257 340 2.5E-26 T 28-03-2018 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 Pfam PF09383 NIL domain 266 336 1.1E-21 T 28-03-2018 IPR018449 NIL domain A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07160 fae2b4703d229c5ad0b9d3732c32d82b 343 SUPERFAMILY SSF52540 1 238 1.92E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 941 1069 4.35E-24 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1194 1263 2.63E-6 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 656 789 2.98E-12 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 376 512 2.48E-26 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1098 1158 2.59E-9 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1291 1348 1.29E-6 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 241 372 2.9E-20 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1479 1537 3.22E-8 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF00746 LPXTG cell wall anchor motif 1792 1827 2.1E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1282 1368 1.0E-24 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1073 1181 5.2E-22 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1460 1557 1.5E-27 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1369 1459 6.6E-25 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1652 1785 9.3E-30 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1182 1281 3.0E-24 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.810 1558 1651 4.9E-26 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1576 1638 1.37E-7 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.1280 230 382 1.1E-22 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1381 1447 2.43E-6 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1794 1827 3.5E-6 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF05737 Collagen binding domain 947 1065 2.3E-15 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF05737 Collagen binding domain 665 779 2.5E-8 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF05737 Collagen binding domain 797 929 2.8E-26 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF05737 Collagen binding domain 378 506 4.0E-30 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Pfam PF05737 Collagen binding domain 524 636 1.1E-17 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.1280 40 207 1.7E-10 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 515 638 1.68E-23 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.740 939 1072 4.3E-16 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.740 650 791 1.6E-16 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.740 793 938 4.4E-16 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.740 383 514 2.8E-18 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 Gene3D G3DSA:2.60.40.740 515 649 3.4E-14 T 28-03-2018 A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49401 797 939 2.41E-25 T 28-03-2018 IPR008966 Adhesion domain A21D_RS07510 18bc2021bdc7f9aded11b66636b5b23b 1828 SUPERFAMILY SSF49478 1671 1736 1.69E-7 T 28-03-2018 A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 273 2.5E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 SMART SM00062 48 275 4.0E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 75 88 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 Gene3D G3DSA:3.40.190.10 1 165 2.9E-30 T 28-03-2018 A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 Gene3D G3DSA:3.40.190.10 166 288 6.7E-13 T 28-03-2018 A21D_RS11565 cf5a4beb90d48b7c2ec9b48b9bb15b30 292 SUPERFAMILY SSF53850 1 274 1.48E-51 T 28-03-2018 A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 Pfam PF13545 Crp-like helix-turn-helix domain 165 232 1.3E-16 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 SUPERFAMILY SSF46785 160 231 3.43E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 Pfam PF00027 Cyclic nucleotide-binding domain 46 130 9.8E-21 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 Gene3D G3DSA:1.10.10.10 162 234 7.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 Gene3D G3DSA:2.60.120.10 17 161 3.8E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 SMART SM00100 27 148 1.2E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 SMART SM00419 178 227 1.1E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 SUPERFAMILY SSF51206 24 153 6.15E-35 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 200 4.4E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS05535 a04839cec156ab7580ec60b841164a58 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 200 215 4.4E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS11480 e4a482d577e4b1508cc7a68ef76672b3 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A21D_RS11480 e4a482d577e4b1508cc7a68ef76672b3 389 Gene3D G3DSA:3.90.1150.10 8 254 4.3E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11480 e4a482d577e4b1508cc7a68ef76672b3 389 Pfam PF00155 Aminotransferase class I and II 32 382 5.3E-63 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS11480 e4a482d577e4b1508cc7a68ef76672b3 389 Gene3D G3DSA:3.90.1150.10 255 389 4.2E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11480 e4a482d577e4b1508cc7a68ef76672b3 389 SUPERFAMILY SSF53383 1 385 3.85E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 1 481 69.021 T 28-03-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 Gene3D G3DSA:3.40.309.10 266 459 1.3E-62 T 28-03-2018 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 Gene3D G3DSA:3.40.605.10 1 265 1.6E-92 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 Pfam PF00171 Aldehyde dehydrogenase family 15 477 4.0E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 481 4.3E-180 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 SUPERFAMILY SSF53720 4 481 8.51E-153 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS01980 7f509e3ff951d9b89e3b6e5412ade87b 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS10595 1e084f5820398427710d2dab45f95822 191 Gene3D G3DSA:1.25.10.10 64 186 3.6E-5 T 28-03-2018 IPR011989 Armadillo-like helical A21D_RS10595 1e084f5820398427710d2dab45f95822 191 Gene3D G3DSA:1.10.10.60 4 62 2.9E-8 T 28-03-2018 A21D_RS10595 1e084f5820398427710d2dab45f95822 191 Pfam PF14278 Transcriptional regulator C-terminal region 89 161 7.5E-14 T 28-03-2018 A21D_RS10595 1e084f5820398427710d2dab45f95822 191 SUPERFAMILY SSF46689 6 73 2.89E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 SUPERFAMILY SSF55653 58 147 3.66E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 Gene3D G3DSA:3.10.430.100 63 147 5.9E-31 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 Gene3D G3DSA:3.40.5.10 1 49 6.2E-25 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 SUPERFAMILY SSF55658 1 55 1.46E-18 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.198 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 7.4E-48 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 9.4E-24 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07360 60e42e6eb47f3c1a684f50c92975a10a 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 2.0E-29 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 Gene3D G3DSA:3.30.1330.10 27 158 2.5E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 Gene3D G3DSA:3.90.650.10 168 338 4.7E-58 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 160 5.2E-17 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 SUPERFAMILY SSF56042 168 336 2.99E-56 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 336 2.7E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 338 46.066 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 330 7.9E-134 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10960 2224f4653e72a838a8adbd50f32619c4 338 SUPERFAMILY SSF55326 4 166 1.18E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 Gene3D G3DSA:3.30.200.20 1 107 5.6E-28 T 28-03-2018 A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 400 134.728 T 28-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 Pfam PF01636 Phosphotransferase enzyme family 34 268 2.5E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 393 9.2E-86 T 28-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 PIRSF PIRSF031134 2 400 1.6E-131 T 28-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 SUPERFAMILY SSF56112 10 397 4.66E-74 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS05725 8e2923b156ac82fb747b86f1b0e3ba06 400 Gene3D G3DSA:3.90.1200.10 108 331 1.9E-13 T 28-03-2018 A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 SUPERFAMILY SSF55874 219 342 4.45E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 Gene3D G3DSA:3.30.565.10 216 343 6.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 342 2.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 Pfam PF07730 Histidine kinase 148 213 4.6E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 PIRSF PIRSF037431 1 343 2.0E-102 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 A21D_RS13190 3c954a066a075eb71b435c8ef6297791 343 SMART SM00387 252 343 0.0011 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 555 27.17 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Pfam PF05746 DALR anticodon binding domain 437 555 3.0E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 96 6.4E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 555 1.9E-162 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Gene3D G3DSA:3.30.1360.70 2 113 2.4E-29 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Gene3D G3DSA:3.40.50.620 114 367 5.3E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 SMART SM01016 5 96 5.6E-35 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Gene3D G3DSA:1.10.730.10 403 555 1.4E-47 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 SUPERFAMILY SSF47323 431 555 2.03E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 SUPERFAMILY SSF55190 8 116 1.2E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 Pfam PF00750 tRNA synthetases class I (R) 105 410 3.8E-26 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 SUPERFAMILY SSF52374 120 447 7.04E-92 T 28-03-2018 A21D_RS07940 245d7524a224fa70e0c3ec7f940234bc 555 SMART SM00836 437 555 7.8E-49 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:3.40.50.980 448 588 3.4E-24 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:3.30.300.30 838 957 7.5E-22 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 SMART SM00823 Phosphopantetheine attachment site 951 1020 7.6E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:3.30.559.10 2 192 1.2E-17 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:3.40.50.980 589 747 6.0E-22 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 SUPERFAMILY SSF56801 446 939 4.97E-98 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:2.30.38.10 748 835 3.6E-16 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Pfam PF00501 AMP-binding enzyme 462 843 6.8E-55 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Pfam PF00550 Phosphopantetheine attachment site 954 1015 4.7E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Gene3D G3DSA:1.10.1200.10 958 1023 5.2E-11 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 SUPERFAMILY SSF47336 947 1016 3.93E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 SUPERFAMILY SSF52777 187 416 2.78E-27 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 SUPERFAMILY SSF52777 10 182 1.11E-23 T 28-03-2018 A21D_RS11930 361176be80a2b2b7b65ec2f51db43399 1061 Pfam PF00668 Condensation domain 6 431 1.9E-52 T 28-03-2018 IPR001242 Condensation domain A21D_RS19640 09b8ed4574ebcc84ad5fa446fed98958 1289 Gene3D G3DSA:1.20.120.330 10 217 7.7E-8 T 28-03-2018 A21D_RS19640 09b8ed4574ebcc84ad5fa446fed98958 1289 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 176 513 1.6E-73 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS19640 09b8ed4574ebcc84ad5fa446fed98958 1289 Gene3D G3DSA:1.20.120.20 369 505 4.2E-4 T 28-03-2018 A21D_RS19640 09b8ed4574ebcc84ad5fa446fed98958 1289 Pfam PF10145 Phage-related minor tail protein 209 407 6.4E-51 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:3.40.50.20 3 115 8.4E-35 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SMART SM00851 956 1040 2.4E-5 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1061 12.041 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF56059 127 397 1.11E-106 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF52440 553 671 5.47E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:3.40.50.20 533 658 9.4E-55 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:3.30.470.20 117 399 5.6E-58 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Pfam PF02142 MGS-like domain 959 1040 3.3E-11 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1048 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 835 842 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 421 541 9.1E-38 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF48108 393 547 4.05E-46 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF56059 670 929 2.69E-81 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF52335 945 1069 7.33E-17 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 162 176 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:3.30.470.20 661 934 3.6E-48 T 28-03-2018 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:1.10.1030.10 406 532 3.3E-47 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 166 178 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 237 254 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 202 221 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 376 394 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 294 323 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 46 56 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 17 31 1.4E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 294 301 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SUPERFAMILY SSF52440 4 125 1.87E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Gene3D G3DSA:3.40.50.1380 935 1073 1.4E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 127 331 3.6E-76 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 871 1.3E-31 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS12795 93179c816907a5761211790760a3e9aa 1080 SMART SM01096 418 541 2.1E-55 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 Pfam PF00849 RNA pseudouridylate synthase 62 194 2.4E-23 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 225 3.6E-47 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 SUPERFAMILY SSF55174 1 59 5.49E-13 T 28-03-2018 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 SUPERFAMILY SSF55120 48 234 1.2E-44 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 Gene3D G3DSA:3.30.70.580 58 143 1.9E-21 T 28-03-2018 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 SMART SM00363 1 61 6.9E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 Gene3D G3DSA:3.10.290.10 1 57 3.0E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 Gene3D G3DSA:3.30.70.1560 144 212 5.3E-23 T 28-03-2018 A21D_RS14240 291c72877e8ea034b5a0391f4c18cf08 236 Pfam PF01479 S4 domain 1 44 1.7E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS10030 9fad9b71f8efd2b384f165ccdfa1e20c 289 Gene3D G3DSA:3.30.750.24 147 269 4.3E-13 T 28-03-2018 IPR002645 STAS domain A21D_RS10030 9fad9b71f8efd2b384f165ccdfa1e20c 289 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 11 135 6.0E-48 T 28-03-2018 A21D_RS10030 9fad9b71f8efd2b384f165ccdfa1e20c 289 Pfam PF01740 STAS domain 155 244 3.6E-12 T 28-03-2018 IPR002645 STAS domain A21D_RS10030 9fad9b71f8efd2b384f165ccdfa1e20c 289 SUPERFAMILY SSF52091 150 255 6.08E-17 T 28-03-2018 IPR002645 STAS domain A21D_RS10030 9fad9b71f8efd2b384f165ccdfa1e20c 289 Pfam PF08678 Rsbr N terminal 10 136 7.4E-40 T 28-03-2018 IPR014792 RsbS co-antagonist protein RsbRA N-terminal domain A21D_RS15490 86831642ecf2b68019eb04729b40c7dc 459 Pfam PF02378 Phosphotransferase system, EIIC 125 394 2.2E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS15490 86831642ecf2b68019eb04729b40c7dc 459 SUPERFAMILY SSF55604 7 81 4.18E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS15490 86831642ecf2b68019eb04729b40c7dc 459 Pfam PF00367 phosphotransferase system, EIIB 9 42 2.9E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS15490 86831642ecf2b68019eb04729b40c7dc 459 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS15490 86831642ecf2b68019eb04729b40c7dc 459 Gene3D G3DSA:3.30.1360.60 5 81 1.3E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 Gene3D G3DSA:1.20.200.10 198 492 8.5E-120 T 28-03-2018 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 492 43.136 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 Gene3D G3DSA:1.10.275.10 1 196 1.6E-71 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 SUPERFAMILY SSF48557 2 492 6.36E-186 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 Pfam PF00221 Aromatic amino acid lyase 9 454 3.2E-189 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A21D_RS12575 82340ab03f7e17ad708d37e7d442409e 493 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 491 5.7E-210 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS15925 f81e450f994e3e95214442ad4ac121b8 633 PIRSF PIRSF005091 1 630 8.5E-181 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like A21D_RS15925 f81e450f994e3e95214442ad4ac121b8 633 Pfam PF00884 Sulfatase 245 537 4.3E-37 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A21D_RS15925 f81e450f994e3e95214442ad4ac121b8 633 SUPERFAMILY SSF53649 243 629 3.36E-71 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS15925 f81e450f994e3e95214442ad4ac121b8 633 Gene3D G3DSA:3.40.720.10 239 547 5.3E-40 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 Pfam PF00384 Molybdopterin oxidoreductase 124 577 9.8E-41 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 Gene3D G3DSA:2.40.40.20 654 775 3.6E-11 T 28-03-2018 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 SUPERFAMILY SSF53706 75 644 8.64E-127 T 28-03-2018 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 Pfam PF01568 Molydopterin dinucleotide binding domain 656 752 2.1E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 17 759 7.6E-258 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 PIRSF PIRSF000144 95 762 5.6E-108 T 28-03-2018 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 Gene3D G3DSA:3.40.50.740 333 626 4.6E-44 T 28-03-2018 A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 SUPERFAMILY SSF50692 647 759 2.49E-12 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A21D_RS08800 1b2a4959aac9a915c7b1d752c6d03f41 783 Gene3D G3DSA:3.40.50.740 126 289 6.2E-35 T 28-03-2018 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 Pfam PF07687 Peptidase dimerisation domain 181 274 2.5E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 1.3E-155 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 Gene3D G3DSA:3.40.630.10 2 373 2.0E-63 T 28-03-2018 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 SUPERFAMILY SSF53187 288 372 3.83E-63 T 28-03-2018 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 SUPERFAMILY SSF53187 5 178 3.83E-63 T 28-03-2018 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 PIRSF PIRSF001123 257 373 6.7E-8 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 PIRSF PIRSF001123 83 191 1.0E-4 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 PIRSF PIRSF001123 4 100 7.0E-4 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 SUPERFAMILY SSF55031 180 284 5.63E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 Pfam PF01546 Peptidase family M20/M25/M40 74 368 5.2E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS16240 1936bafc810e56ffd106ae0f7a54b20b 373 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A21D_RS04180 e4dfbfadb3661ddeecaad28a33616998 352 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 245 2.5E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS04180 e4dfbfadb3661ddeecaad28a33616998 352 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 99 246 3.0E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS16435 01fa1080d7e0c3db8f1f18690ed6c25c 396 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 48 396 9.1E-80 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 A21D_RS16435 01fa1080d7e0c3db8f1f18690ed6c25c 396 Pfam PF01578 Cytochrome C assembly protein 72 393 3.5E-37 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 Gene3D G3DSA:3.40.50.720 1 178 4.1E-39 T 28-03-2018 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 SUPERFAMILY SSF48179 180 332 1.09E-55 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 Gene3D G3DSA:1.10.1040.10 189 337 1.4E-55 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 159 1.6E-53 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 1.7E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 320 1.3E-52 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 SUPERFAMILY SSF51735 3 178 6.25E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 322 37.496 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS16555 9de242a8f1077aa6e87dc1b09544cd48 345 PIRSF PIRSF000114 1 332 3.0E-107 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 8 49 5.1E-9 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 Gene3D G3DSA:1.10.10.10 269 365 1.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 Pfam PF04963 Sigma-54 factor, core binding domain 72 256 1.1E-41 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 315 334 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 Pfam PF04552 Sigma-54, DNA binding domain 268 426 6.5E-53 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 PIRSF PIRSF000774 1 428 4.7E-100 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 426 4.7E-120 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 PRINTS PR00045 Sigma-54 factor signature 402 420 5.8E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 PRINTS PR00045 Sigma-54 factor signature 327 339 5.8E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 PRINTS PR00045 Sigma-54 factor signature 142 159 5.8E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS00545 4a705c31137ad6e56b7b69929a15b5c3 428 PRINTS PR00045 Sigma-54 factor signature 343 354 5.8E-22 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 Pfam PF02445 Quinolinate synthetase A protein 29 366 1.5E-105 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 Gene3D G3DSA:3.40.50.10800 21 107 3.1E-17 T 28-03-2018 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 Gene3D G3DSA:3.40.50.10800 112 236 1.2E-22 T 28-03-2018 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 367 55.005 T 28-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 SUPERFAMILY SSF142754 36 366 7.72E-97 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 Gene3D G3DSA:3.40.50.10800 237 345 2.5E-24 T 28-03-2018 A21D_RS03460 a334113b8f39ea28dcbc0102977d30ff 368 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 22 366 6.1E-114 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 Pfam PF01979 Amidohydrolase family 51 420 1.8E-44 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 422 2.2E-147 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 SUPERFAMILY SSF51338 1 53 5.58E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 SUPERFAMILY SSF51338 366 422 5.58E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 Gene3D G3DSA:3.20.20.140 68 406 1.6E-106 T 28-03-2018 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 Gene3D G3DSA:2.30.40.10 1 67 3.8E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 424 45.224 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18290 52535660debcfdc5f4fafe3d99d79eac 425 SUPERFAMILY SSF51556 54 366 1.48E-112 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS11530 0a33aff4655554c8ef0b969685b46555 287 SUPERFAMILY SSF55797 163 281 9.94E-29 T 28-03-2018 IPR014044 CAP domain A21D_RS11530 0a33aff4655554c8ef0b969685b46555 287 Gene3D G3DSA:3.40.33.10 158 285 2.6E-23 T 28-03-2018 IPR014044 CAP domain A21D_RS11530 0a33aff4655554c8ef0b969685b46555 287 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 164 286 1.7E-59 T 28-03-2018 IPR014258 CAP domain, YkwD-like A21D_RS11530 0a33aff4655554c8ef0b969685b46555 287 Pfam PF00188 Cysteine-rich secretory protein family 172 284 1.4E-24 T 28-03-2018 IPR014044 CAP domain A21D_RS08135 ef0c9022f7499e66476cfcf429b9cbc9 185 Gene3D G3DSA:1.10.10.60 2 51 5.6E-13 T 28-03-2018 A21D_RS08135 ef0c9022f7499e66476cfcf429b9cbc9 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 62 5.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS08135 ef0c9022f7499e66476cfcf429b9cbc9 185 Gene3D G3DSA:1.10.10.60 52 169 7.0E-8 T 28-03-2018 A21D_RS08135 ef0c9022f7499e66476cfcf429b9cbc9 185 SUPERFAMILY SSF46689 8 66 8.21E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 Gene3D G3DSA:3.40.50.150 161 382 7.7E-34 T 28-03-2018 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 SUPERFAMILY SSF53335 255 361 1.12E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 SUPERFAMILY SSF53335 144 218 1.12E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 Pfam PF02926 THUMP domain 15 155 1.0E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 2.6E-56 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 SMART SM00981 57 155 1.0E-6 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A21D_RS16805 d632b8ee415b0e9e1d6b8d9d80f540f9 383 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS19415 271835893f2b81149938eb0af84226d1 198 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 19 142 3.0E-35 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 A21D_RS19415 271835893f2b81149938eb0af84226d1 198 Gene3D G3DSA:3.40.1130.10 1 198 4.3E-33 T 28-03-2018 A21D_RS19415 271835893f2b81149938eb0af84226d1 198 SUPERFAMILY SSF69593 7 193 1.03E-36 T 28-03-2018 A21D_RS19415 271835893f2b81149938eb0af84226d1 198 Pfam PF01553 Acyltransferase 18 141 7.7E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS19415 271835893f2b81149938eb0af84226d1 198 SMART SM00563 33 144 2.4E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 Gene3D G3DSA:3.40.1390.20 3 132 1.6E-40 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 301 6.8E-119 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 Gene3D G3DSA:3.40.50.300 133 307 2.0E-48 T 28-03-2018 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 SUPERFAMILY SSF53795 132 299 7.94E-43 T 28-03-2018 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 Pfam PF02603 HPr Serine kinase N terminus 4 127 1.9E-37 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 41.885 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 SUPERFAMILY SSF75138 4 130 6.28E-37 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS00710 50f3beb1f4d787774f6e49bb964fe6d4 311 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 5.6E-78 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A21D_RS14850 0f605c7a01365a217c4f275b61032a83 536 Pfam PF13751 Transposase DDE domain 393 518 5.3E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS14850 0f605c7a01365a217c4f275b61032a83 536 Gene3D G3DSA:3.90.350.10 230 497 2.7E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS14850 0f605c7a01365a217c4f275b61032a83 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS02955 0f605c7a01365a217c4f275b61032a83 536 Pfam PF13751 Transposase DDE domain 393 518 5.3E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS02955 0f605c7a01365a217c4f275b61032a83 536 Gene3D G3DSA:3.90.350.10 230 497 2.7E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS02955 0f605c7a01365a217c4f275b61032a83 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 16 348 4.7E-120 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 31 42 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 16 348 40.481 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 Pfam PF13353 4Fe-4S single cluster domain 33 139 9.0E-8 T 28-03-2018 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 Pfam PF06463 Molybdenum Cofactor Synthesis C 200 327 2.0E-37 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 SUPERFAMILY SSF102114 18 305 1.7E-80 T 28-03-2018 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 Pfam PF04055 Radical SAM superfamily 29 190 7.3E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 Gene3D G3DSA:3.20.20.70 12 348 6.6E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS09260 53b589e8bc12de6cbaec5a3980972cf5 348 SMART SM00729 25 233 1.4E-11 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS12520 eb658c1affeaefd4b154caf92b2e5f3e 211 SUPERFAMILY SSF53098 7 171 5.38E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12520 eb658c1affeaefd4b154caf92b2e5f3e 211 Pfam PF00929 Exonuclease 11 163 5.4E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS12520 eb658c1affeaefd4b154caf92b2e5f3e 211 Gene3D G3DSA:3.30.420.10 8 182 2.0E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12520 eb658c1affeaefd4b154caf92b2e5f3e 211 SMART SM00479 9 172 1.3E-25 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS11665 d1b031bd5a4cb0dee5e2aa8d17f08f37 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11665 d1b031bd5a4cb0dee5e2aa8d17f08f37 131 SMART SM00345 17 76 1.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11665 d1b031bd5a4cb0dee5e2aa8d17f08f37 131 SUPERFAMILY SSF46785 6 83 3.47E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11665 d1b031bd5a4cb0dee5e2aa8d17f08f37 131 Gene3D G3DSA:1.10.10.10 1 78 4.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 Gene3D G3DSA:3.10.20.30 1 111 3.0E-25 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 SUPERFAMILY SSF46548 114 238 2.09E-28 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 Gene3D G3DSA:1.10.1060.10 113 249 2.9E-20 T 28-03-2018 A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 Pfam PF13183 4Fe-4S dicluster domain 151 226 4.1E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 117 5.7E-28 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 12 233 8.6E-42 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14835 dc7dcc7a19b644e40740c2e4d1642c76 254 SUPERFAMILY SSF54292 4 112 3.87E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Pfam PF02929 Beta galactosidase small chain 722 992 3.0E-66 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Gene3D G3DSA:2.60.40.10 592 700 6.3E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SUPERFAMILY SSF74650 706 993 5.81E-77 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Pfam PF00703 Glycosyl hydrolases family 2 212 306 2.2E-11 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SUPERFAMILY SSF51445 308 590 1.18E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SUPERFAMILY SSF49785 7 206 4.82E-60 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Pfam PF16353 Domain of unknown function(DUF4981) 607 689 1.1E-11 T 28-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 358 383 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SMART SM01038 720 993 2.2E-90 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 423 437 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 40 206 6.7E-44 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Gene3D G3DSA:2.70.98.10 704 995 3.6E-81 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 PRINTS PR00132 Glycosyl hydrolase family 2 signature 134 149 1.4E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 PRINTS PR00132 Glycosyl hydrolase family 2 signature 348 366 1.4E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 PRINTS PR00132 Glycosyl hydrolase family 2 signature 317 331 1.4E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 PRINTS PR00132 Glycosyl hydrolase family 2 signature 498 513 1.4E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 PRINTS PR00132 Glycosyl hydrolase family 2 signature 423 438 1.4E-32 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Gene3D G3DSA:2.60.40.10 208 306 3.4E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SUPERFAMILY SSF49303 588 693 1.58E-14 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 308 595 4.0E-107 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Gene3D G3DSA:2.60.120.260 1 206 5.3E-56 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 SUPERFAMILY SSF49303 210 306 4.6E-19 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A21D_RS03720 44810dc8e0a36dce009983d7566547e5 1010 Gene3D G3DSA:3.20.20.80 307 591 3.1E-77 T 28-03-2018 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 SUPERFAMILY SSF52794 398 478 1.41E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Gene3D G3DSA:1.10.10.10 2 62 1.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Gene3D G3DSA:1.10.10.10 85 154 5.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 581 597 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 SUPERFAMILY SSF55804 530 675 3.53E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Gene3D G3DSA:3.40.50.2300 394 482 4.1E-16 T 28-03-2018 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Pfam PF00874 PRD domain 296 384 1.1E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Gene3D G3DSA:3.40.930.10 531 675 4.1E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Gene3D G3DSA:1.10.1790.10 283 389 2.5E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 SUPERFAMILY SSF63520 267 389 5.23E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS19440 cb8f860a17046424fb9f7f9462582ca4 675 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 534 675 4.7E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS13275 608f798a858810d9904af8155ee2717b 218 Pfam PF09335 SNARE associated Golgi protein 52 170 3.3E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein A21D_RS17020 22ba584002d54a6090ed2ceb59d50b7c 69 Gene3D G3DSA:2.40.50.100 1 53 4.4E-19 T 28-03-2018 A21D_RS17020 22ba584002d54a6090ed2ceb59d50b7c 69 Gene3D G3DSA:2.40.50.100 54 67 0.032 T 28-03-2018 A21D_RS17020 22ba584002d54a6090ed2ceb59d50b7c 69 SUPERFAMILY SSF51230 2 69 7.72E-22 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS17020 22ba584002d54a6090ed2ceb59d50b7c 69 Pfam PF00364 Biotin-requiring enzyme 3 68 3.1E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Gene3D G3DSA:3.40.50.720 106 230 5.6E-21 T 28-03-2018 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Pfam PF07885 Ion channel 23 95 8.0E-15 T 28-03-2018 IPR013099 Potassium channel domain A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Pfam PF02254 TrkA-N domain 118 239 3.2E-16 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 SUPERFAMILY SSF116726 298 331 7.59E-5 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 SUPERFAMILY SSF81324 14 132 1.05E-25 T 28-03-2018 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Gene3D G3DSA:1.20.5.110 63 98 2.5E-6 T 28-03-2018 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Gene3D G3DSA:1.10.287.70 12 61 4.4E-11 T 28-03-2018 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 Gene3D G3DSA:3.30.70.1450 231 334 7.9E-4 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS14025 e7ea26cca258c4778558fc374b3714e0 334 SUPERFAMILY SSF51735 115 252 6.1E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.30.300.30 1834 1954 1.5E-25 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1972 1987 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00550 Phosphopantetheine attachment site 1950 2010 1.9E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00550 Phosphopantetheine attachment site 639 687 4.8E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF53901 39 415 4.33E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1585 1596 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF56801 1582 1933 1.12E-102 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF56801 1165 1324 1.12E-102 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:2.30.38.10 1753 1832 3.2E-18 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.40.47.10 34 304 1.1E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF13649 Methyltransferase domain 1365 1461 7.6E-15 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.40.50.150 1310 1532 2.9E-25 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF47336 1944 2010 3.8E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF52777 2031 2205 9.23E-26 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.30.559.10 699 919 1.1E-26 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00501 AMP-binding enzyme 1173 1307 2.0E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00501 AMP-binding enzyme 1571 1839 1.7E-51 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 42 292 2.0E-55 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.40.47.10 308 476 4.1E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.30.559.10 2011 2195 8.8E-15 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 300 418 1.4E-36 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.40.50.980 1163 1309 2.7E-16 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF52777 2211 2459 1.67E-20 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:1.10.1200.10 627 692 7.7E-6 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:1.10.1200.10 1955 2010 2.3E-14 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00668 Condensation domain 718 1141 3.5E-92 T 28-03-2018 IPR001242 Condensation domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF00668 Condensation domain 2027 2458 2.2E-44 T 28-03-2018 IPR001242 Condensation domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Gene3D G3DSA:3.40.50.980 1565 1752 5.0E-30 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 421 536 1.2E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF52777 721 894 5.11E-36 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF53335 1330 1488 2.07E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF52777 901 1145 8.12E-45 T 28-03-2018 A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SUPERFAMILY SSF47336 633 687 3.14E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 SMART SM00825 Beta-ketoacyl synthase 44 474 6.6E-128 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A21D_RS11910 d1284c070a9605706c89347a501943df 2466 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 208 226 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 Pfam PF00581 Rhodanese-like domain 8 126 4.3E-13 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 SUPERFAMILY SSF52540 143 264 1.88E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 19 317 1.4E-95 T 28-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 SMART SM00450 5 131 4.9E-16 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 Gene3D G3DSA:3.40.50.300 139 346 2.4E-11 T 28-03-2018 A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 SUPERFAMILY SSF52821 3 138 1.44E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS13440 6fdbb04dbab70e31d4daf4425891342a 347 Gene3D G3DSA:3.40.250.10 1 138 2.7E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 SUPERFAMILY SSF56645 1 242 1.31E-91 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.4E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Gene3D G3DSA:1.10.540.10 1 122 2.2E-39 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.6E-40 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Gene3D G3DSA:2.40.110.10 123 217 8.8E-41 T 28-03-2018 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.0E-29 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 PIRSF PIRSF016578 4 378 4.8E-20 T 28-03-2018 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 SUPERFAMILY SSF47203 228 378 1.61E-61 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS04715 573f7e323cf389fcf46f47688ae5695a 379 Gene3D G3DSA:1.20.140.10 218 379 2.5E-65 T 28-03-2018 A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 76 1.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 Gene3D G3DSA:1.10.10.10 3 88 4.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.5E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.5E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 SUPERFAMILY SSF46785 13 82 5.77E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 SUPERFAMILY SSF48008 84 211 4.18E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 Pfam PF07729 FCD domain 88 213 3.1E-18 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 SMART SM00895 88 217 7.6E-6 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 Gene3D G3DSA:1.20.120.530 89 227 6.6E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS11215 21273e83e80dd1beef7ee8843dad9a07 229 SMART SM00345 21 79 3.8E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SMART SM00530 6 60 1.3E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Gene3D G3DSA:1.25.40.10 68 197 1.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SUPERFAMILY SSF48452 135 342 3.79E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Gene3D G3DSA:1.10.260.40 1 67 5.4E-13 T 28-03-2018 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Gene3D G3DSA:1.25.40.10 281 324 1.5E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SUPERFAMILY SSF47413 2 57 1.83E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SMART SM00028 225 258 1.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SMART SM00028 303 336 440.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SMART SM00028 185 218 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 SMART SM00028 265 298 0.12 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Gene3D G3DSA:1.20.58.280 325 423 0.0042 T 28-03-2018 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Gene3D G3DSA:1.25.40.10 224 280 2.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02580 12492d575e7cfe809d00503bafa63c82 424 Pfam PF01381 Helix-turn-helix 7 57 1.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 SUPERFAMILY SSF102114 114 366 3.66E-56 T 28-03-2018 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 8.4E-26 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 Pfam PF04055 Radical SAM superfamily 149 319 6.7E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 Pfam PF01938 TRAM domain 374 426 4.3E-7 T 28-03-2018 IPR002792 TRAM domain A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 426 1.0E-144 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 Gene3D G3DSA:3.80.30.20 140 375 2.4E-50 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 7.4E-141 T 28-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 A21D_RS15660 47381dc74ab99dc855d570d93730028f 450 SMART SM00729 143 361 1.2E-55 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 391 8.9E-14 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 SUPERFAMILY SSF63418 17 101 5.75E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Pfam PF01225 Mur ligase family, catalytic domain 22 100 1.4E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Pfam PF08245 Mur ligase middle domain 110 291 3.2E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Gene3D G3DSA:3.90.190.20 311 451 1.2E-36 T 28-03-2018 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 SUPERFAMILY SSF53623 105 306 7.98E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 28 448 3.0E-124 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 2 450 31.351 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Gene3D G3DSA:3.40.1390.10 4 94 1.1E-21 T 28-03-2018 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 Gene3D G3DSA:3.40.1190.10 95 307 1.1E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18400 9a601308f3d1a78021c24a5b276a9a4b 451 SUPERFAMILY SSF53244 312 449 1.51E-31 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Pfam PF02142 MGS-like domain 949 1036 2.2E-21 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF56059 128 399 3.18E-109 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 12.963 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 9.5E-43 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF52440 2 127 2.01E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.40.50.20 4 128 5.8E-37 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 SMART SM01096 420 540 2.2E-66 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF52440 550 668 1.73E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF48108 395 546 1.57E-47 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.40.50.1380 928 1061 7.2E-40 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.40.50.20 532 647 1.0E-59 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 SMART SM00851 949 1036 8.6E-31 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF52335 929 1051 3.66E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.0E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 SUPERFAMILY SSF56059 666 927 6.89E-92 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 5.4E-34 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 9.9E-79 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.30.470.20 129 401 8.3E-65 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.30.1490.20 648 739 1.1E-14 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:3.30.470.20 740 927 3.3E-36 T 28-03-2018 A21D_RS18280 52214e244302051eb590185a1a298865 1065 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1045 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Gene3D G3DSA:1.10.1030.10 403 531 4.8E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18280 52214e244302051eb590185a1a298865 1065 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1063 13.356 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 Gene3D G3DSA:3.90.1820.10 1 262 1.1E-57 T 28-03-2018 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 Gene3D G3DSA:3.90.1820.10 263 433 8.0E-51 T 28-03-2018 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 Pfam PF02056 Family 4 glycosyl hydrolase 5 182 9.3E-59 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 407 2.4E-47 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 SUPERFAMILY SSF56327 171 432 6.24E-77 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 SUPERFAMILY SSF51735 4 168 1.78E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 9.7E-44 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS02050 6431cbff0290ec5816cfc1e32fed8efd 433 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 170 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS14200 ef5ec87a93988497aa45db383f912032 82 SMART SM00450 4 82 9.2E-11 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS14200 ef5ec87a93988497aa45db383f912032 82 Gene3D G3DSA:3.40.250.10 2 81 1.8E-24 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS14200 ef5ec87a93988497aa45db383f912032 82 Pfam PF00581 Rhodanese-like domain 4 77 2.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS14200 ef5ec87a93988497aa45db383f912032 82 SUPERFAMILY SSF52821 4 79 1.83E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 SUPERFAMILY SSF56801 7 534 9.29E-137 T 28-03-2018 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Gene3D G3DSA:3.40.50.980 5 183 9.2E-37 T 28-03-2018 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Gene3D G3DSA:2.30.38.10 342 428 1.2E-15 T 28-03-2018 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Gene3D G3DSA:3.30.300.30 429 537 4.3E-24 T 28-03-2018 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Gene3D G3DSA:3.40.50.980 184 341 7.8E-40 T 28-03-2018 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Pfam PF00501 AMP-binding enzyme 15 435 3.8E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS12185 2a1b5e5905742355e5e04651ccc3b30a 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 521 1.1E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 SMART SM00342 96 179 3.6E-32 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 163 179 4.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 148 163 4.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 133 175 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 SUPERFAMILY SSF57884 6 87 7.72E-28 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 PIRSF PIRSF000408 1 186 3.6E-82 T 28-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 Gene3D G3DSA:1.10.10.60 61 132 1.6E-15 T 28-03-2018 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 Gene3D G3DSA:1.10.10.60 133 187 6.2E-14 T 28-03-2018 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 SUPERFAMILY SSF46689 132 182 2.64E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 SUPERFAMILY SSF46689 80 131 1.39E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 Pfam PF12833 Helix-turn-helix domain 102 180 5.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 Gene3D G3DSA:3.40.10.10 2 60 2.5E-23 T 28-03-2018 IPR035451 Ada-like domain A21D_RS05070 cac2d6722e159d6671cff975613cde58 188 Pfam PF02805 Metal binding domain of Ada 9 71 8.6E-27 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Gene3D G3DSA:3.40.50.300 234 436 3.1E-40 T 28-03-2018 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 SMART SM00487 250 439 7.1E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Pfam PF00270 DEAD/DEAH box helicase 255 411 6.3E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Gene3D G3DSA:3.40.50.300 437 609 1.1E-29 T 28-03-2018 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 SMART SM00490 484 569 5.1E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 SUPERFAMILY SSF50249 2 165 6.57E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 SUPERFAMILY SSF52540 170 432 1.1E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Gene3D G3DSA:2.40.50.140 42 136 1.6E-11 T 28-03-2018 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 23 644 2.3E-234 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Pfam PF00271 Helicase conserved C-terminal domain 452 568 1.5E-18 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 Pfam PF17191 RecG wedge domain 6 162 6.8E-12 T 28-03-2018 IPR033454 RecG, wedge domain A21D_RS18125 d995b338c39f58b7fa21ed4633383f5e 676 SUPERFAMILY SSF52540 372 582 6.04E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 4.3E-24 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Gene3D G3DSA:3.30.300.30 418 524 1.1E-27 T 28-03-2018 A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Gene3D G3DSA:3.40.50.980 181 330 1.1E-35 T 28-03-2018 A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Pfam PF00501 AMP-binding enzyme 22 423 5.7E-77 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 SUPERFAMILY SSF56801 20 519 4.06E-134 T 28-03-2018 A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Gene3D G3DSA:3.40.50.980 9 180 1.0E-30 T 28-03-2018 A21D_RS11605 7fb351783d97bbfbfafb591f284a9374 525 Gene3D G3DSA:2.30.38.10 331 416 1.4E-19 T 28-03-2018 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 Gene3D G3DSA:3.30.420.40 249 498 1.8E-76 T 28-03-2018 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 SUPERFAMILY SSF53067 4 255 1.13E-95 T 28-03-2018 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 Hamap MF_00186 Glycerol kinase [glpK]. 3 498 57.263 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 PIRSF PIRSF000538 3 497 2.8E-174 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 2.0E-60 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 Gene3D G3DSA:3.30.420.40 1 248 6.4E-88 T 28-03-2018 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 494 2.5E-225 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 SUPERFAMILY SSF53067 255 493 8.63E-81 T 28-03-2018 A21D_RS01285 4f4dce32aaa533e69045fd1e51993ac1 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 5.6E-87 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A21D_RS15025 baa799c39183ecfe494ecf3de26dab52 164 Pfam PF02566 OsmC-like protein 59 162 1.5E-17 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS15025 baa799c39183ecfe494ecf3de26dab52 164 SUPERFAMILY SSF82784 1 162 4.32E-34 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS15025 baa799c39183ecfe494ecf3de26dab52 164 Gene3D G3DSA:3.30.300.20 1 155 1.9E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS18435 a0004e18c3956ffb312e0fb454127f10 539 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 539 29.266 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC A21D_RS18435 a0004e18c3956ffb312e0fb454127f10 539 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 537 8.1E-176 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC A21D_RS18435 a0004e18c3956ffb312e0fb454127f10 539 PIRSF PIRSF012535 1 539 1.3E-184 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC A21D_RS18435 a0004e18c3956ffb312e0fb454127f10 539 Pfam PF10079 Bacillithiol biosynthesis BshC 1 535 3.5E-163 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 Pfam PF00919 Uncharacterized protein family UPF0004 83 184 1.4E-30 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 Pfam PF04055 Radical SAM superfamily 231 401 3.9E-35 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 Gene3D G3DSA:3.80.30.20 224 460 2.9E-58 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 83 517 4.3E-205 T 28-03-2018 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 231 251 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 Pfam PF01938 TRAM domain 456 517 1.6E-15 T 28-03-2018 IPR002792 TRAM domain A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 82 519 74.444 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 83 515 3.2E-164 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 SMART SM00729 227 445 3.4E-67 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A21D_RS17555 868e12102b60f975e1650ed8ec43b73d 525 SUPERFAMILY SSF102114 215 450 1.06E-65 T 28-03-2018 A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 Gene3D G3DSA:2.20.25.10 277 315 2.3E-7 T 28-03-2018 A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 Gene3D G3DSA:2.40.50.40 208 276 8.0E-15 T 28-03-2018 A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 PIRSF PIRSF036612 4 316 1.6E-76 T 28-03-2018 IPR012046 LytTR transcriptional regulator with ABC transporter ATP-binding domain A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 Pfam PF04397 LytTr DNA-binding domain 217 314 9.9E-24 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 SMART SM00850 216 315 1.7E-28 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 SUPERFAMILY SSF52540 59 179 6.93E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02550 6212cde53032387c1a86d24ba437009c 317 Gene3D G3DSA:3.40.50.300 30 207 3.1E-6 T 28-03-2018 A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 Gene3D G3DSA:3.40.50.300 4 335 1.8E-81 T 28-03-2018 A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 SMART SM00382 35 234 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 Pfam PF00005 ABC transporter 27 184 2.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 SUPERFAMILY SSF52540 34 313 6.09E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 2.0E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10635 944374f980a3977b93a7a5ef0a9d830d 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 1.4E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 419 9.9E-149 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 SUPERFAMILY SSF69742 2 158 1.23E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 PIRSF PIRSF000445 1 435 2.1E-151 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 29.766 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 1.1E-46 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 SUPERFAMILY SSF69075 317 419 1.7E-15 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 SUPERFAMILY SSF51735 163 315 1.69E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 8.4E-46 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 418 2.9E-19 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Gene3D G3DSA:3.40.50.720 161 313 4.2E-28 T 28-03-2018 A21D_RS15105 37eae72e07453ddc8892f89ee91231df 456 Gene3D G3DSA:1.10.1200.70 332 420 6.5E-20 T 28-03-2018 A21D_RS07170 770a46126deede49f491d3817f131752 192 Pfam PF01174 SNO glutamine amidotransferase family 6 185 2.1E-67 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07170 770a46126deede49f491d3817f131752 192 Gene3D G3DSA:3.40.50.880 1 192 2.1E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS07170 770a46126deede49f491d3817f131752 192 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07170 770a46126deede49f491d3817f131752 192 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 184 3.3E-81 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07170 770a46126deede49f491d3817f131752 192 SUPERFAMILY SSF52317 3 186 7.15E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS07170 770a46126deede49f491d3817f131752 192 PIRSF PIRSF005639 1 191 2.2E-75 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07170 770a46126deede49f491d3817f131752 192 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.951 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 Gene3D G3DSA:3.40.50.300 19 339 5.1E-84 T 28-03-2018 A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 253 317 2.9E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 SMART SM00382 58 250 3.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 251 337 2.1E-29 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 SUPERFAMILY SSF52540 23 272 3.13E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10810 dbf7994696d0a7e915bff50ba7295c21 339 Pfam PF00005 ABC transporter 50 200 6.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PIRSF PIRSF000676 1 298 5.0E-88 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 86 97 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 Gene3D G3DSA:3.30.230.10 2 161 1.5E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 TIGRFAM TIGR00191 thrB: homoserine kinase 4 285 4.0E-82 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 Hamap MF_00384 Homoserine kinase [thrB]. 4 295 30.252 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 Gene3D G3DSA:3.30.70.890 162 291 9.6E-23 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PRINTS PR00958 Homoserine kinase signature 246 261 3.4E-38 T 28-03-2018 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PRINTS PR00958 Homoserine kinase signature 93 108 3.4E-38 T 28-03-2018 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PRINTS PR00958 Homoserine kinase signature 127 140 3.4E-38 T 28-03-2018 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PRINTS PR00958 Homoserine kinase signature 11 26 3.4E-38 T 28-03-2018 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 PRINTS PR00958 Homoserine kinase signature 166 183 3.4E-38 T 28-03-2018 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 SUPERFAMILY SSF55060 161 281 4.86E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 Pfam PF00288 GHMP kinases N terminal domain 80 140 5.5E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 Pfam PF08544 GHMP kinases C terminal 202 279 1.4E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS03660 8bd31de99f7b6bdbeb08ff0ce05dcb6c 298 SUPERFAMILY SSF54211 1 149 3.64E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 SUPERFAMILY SSF56784 1 258 1.49E-61 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 254 4.9E-60 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 Gene3D G3DSA:3.40.50.1000 1 261 1.2E-35 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 ProSitePatterns PS01229 Hypothetical cof family signature 2. 209 231 - T 28-03-2018 A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 254 6.2E-61 T 28-03-2018 IPR000150 Cof family GO:0016787 A21D_RS01230 a14ed475e9974c4c7887640124705bae 262 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 228 5.3E-29 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 SUPERFAMILY SSF63520 303 400 7.98E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 410 485 3.3E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:1.10.10.10 1 68 4.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:1.10.10.10 85 152 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 593 609 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:1.10.1790.10 186 287 5.0E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 SUPERFAMILY SSF55804 543 689 4.06E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 547 688 1.4E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF08279 HTH domain 4 46 1.7E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:1.10.1790.10 295 400 4.0E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:3.40.50.2300 405 492 1.6E-16 T 28-03-2018 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 SUPERFAMILY SSF52794 410 487 3.61E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF05043 Mga helix-turn-helix domain 89 158 1.5E-4 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 SUPERFAMILY SSF63520 185 282 2.75E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Gene3D G3DSA:3.40.930.10 544 690 8.4E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF00874 PRD domain 308 395 3.0E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS13810 c52bc5010b7dbb7ae5a159e5e9f3fdc8 692 Pfam PF00874 PRD domain 197 280 6.0E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12325 dfd1f1b827fadddb70123df6edc91407 305 Gene3D G3DSA:1.10.3720.10 1 303 1.3E-41 T 28-03-2018 A21D_RS12325 dfd1f1b827fadddb70123df6edc91407 305 SUPERFAMILY SSF161098 79 288 1.83E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12325 dfd1f1b827fadddb70123df6edc91407 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 303 2.7E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 SUPERFAMILY SSF57783 4 98 6.8E-37 T 28-03-2018 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Gene3D G3DSA:1.10.860.10 465 561 3.0E-12 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 PIRSF PIRSF002811 2 602 8.1E-176 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Pfam PF01807 CHC2 zinc finger 6 99 8.0E-39 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 SMART SM00493 260 331 2.2E-18 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Gene3D G3DSA:3.40.1360.10 242 366 2.6E-32 T 28-03-2018 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Gene3D G3DSA:3.90.980.10 109 241 4.4E-39 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 SMART SM00400 36 90 4.3E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Pfam PF10410 DnaB-helicase binding domain of primase 370 421 1.2E-10 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Pfam PF13155 Toprim-like 263 347 5.1E-17 T 28-03-2018 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Gene3D G3DSA:1.20.50.20 368 420 9.9E-4 T 28-03-2018 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 SUPERFAMILY SSF48024 460 561 2.35E-9 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 TIGRFAM TIGR01391 dnaG: DNA primase 5 418 1.7E-144 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 253 1.9E-38 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 SUPERFAMILY SSF56731 116 425 1.31E-99 T 28-03-2018 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Hamap MF_00974 DNA primase [dnaG]. 4 592 28.819 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A21D_RS15760 6a72648936409435b5df1830fb8afe60 605 Gene3D G3DSA:3.90.580.10 1 102 2.1E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 2 447 6.6E-120 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 29 429 7.8E-101 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 Gene3D G3DSA:3.40.710.10 1 452 1.2E-26 T 28-03-2018 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 SUPERFAMILY SSF56601 10 450 1.76E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 42 61 2.0E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 272 294 2.0E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 344 358 2.0E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 329 343 2.0E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS18940 d095daf385d6342aa964240cef8e776a 452 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 407 420 2.0E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 3 411 3.2E-210 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 Gene3D G3DSA:3.40.640.10 170 301 3.4E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 Pfam PF00202 Aminotransferase class-III 20 407 9.8E-81 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 415 3.6E-157 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 Gene3D G3DSA:3.90.1150.10 302 417 3.2E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 PIRSF PIRSF000521 120 413 1.8E-37 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 PIRSF PIRSF000521 1 127 6.2E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 Gene3D G3DSA:3.90.1150.10 2 166 9.5E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 SUPERFAMILY SSF53383 9 410 8.36E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS19270 a5a07b0d5ecc0bce6369506c1216c3ac 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 267 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS05705 a23713989037ea1ceba30330f368b794 337 Gene3D G3DSA:3.40.50.720 147 275 3.3E-26 T 28-03-2018 A21D_RS05705 a23713989037ea1ceba30330f368b794 337 SUPERFAMILY SSF50129 2 141 2.13E-38 T 28-03-2018 IPR011032 GroES-like A21D_RS05705 a23713989037ea1ceba30330f368b794 337 Pfam PF00107 Zinc-binding dehydrogenase 156 291 5.1E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS05705 a23713989037ea1ceba30330f368b794 337 SUPERFAMILY SSF51735 121 298 6.25E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS05705 a23713989037ea1ceba30330f368b794 337 Pfam PF16884 N-terminal domain of oxidoreductase 5 111 1.3E-35 T 28-03-2018 A21D_RS05705 a23713989037ea1ceba30330f368b794 337 SMART SM00829 14 331 1.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS05705 a23713989037ea1ceba30330f368b794 337 Gene3D G3DSA:3.90.180.10 1 146 9.8E-37 T 28-03-2018 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 Gene3D G3DSA:3.40.190.10 92 175 3.5E-21 T 28-03-2018 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 Gene3D G3DSA:1.10.10.10 1 91 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 SUPERFAMILY SSF53850 90 290 2.29E-43 T 28-03-2018 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.7E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.7E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.7E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 Gene3D G3DSA:3.40.190.10 176 258 4.3E-23 T 28-03-2018 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.1E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 SUPERFAMILY SSF46785 3 110 1.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08405 7fbd23c3a6b5da7c3d20bbfbc2a4e1ed 292 Pfam PF03466 LysR substrate binding domain 87 289 2.0E-47 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Pfam PF04542 Sigma-70 region 2 45 100 1.5E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PRINTS PR00046 Major sigma-70 factor signature 237 248 7.7E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PRINTS PR00046 Major sigma-70 factor signature 55 68 7.7E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PRINTS PR00046 Major sigma-70 factor signature 205 217 7.7E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PRINTS PR00046 Major sigma-70 factor signature 79 87 7.7E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PRINTS PR00046 Major sigma-70 factor signature 222 237 7.7E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 PIRSF PIRSF000770 16 256 9.2E-39 T 28-03-2018 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Gene3D G3DSA:1.10.1740.10 17 98 9.2E-17 T 28-03-2018 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Pfam PF04545 Sigma-70, region 4 202 248 3.1E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Gene3D G3DSA:1.10.10.10 195 259 1.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 SUPERFAMILY SSF88946 9 100 8.32E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 SUPERFAMILY SSF88659 176 254 2.62E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Pfam PF04539 Sigma-70 region 3 107 165 1.4E-12 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 SUPERFAMILY SSF88659 101 162 8.9E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 28 252 4.1E-77 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 250 2.8E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 Gene3D G3DSA:1.10.10.10 101 148 5.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17810 83e109b215aff8bc879e32ead60589c3 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 222 248 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS12465 6a19de90331a557eed9be4d32e899fd4 331 Pfam PF13379 NMT1-like family 28 267 3.4E-26 T 28-03-2018 A21D_RS12465 6a19de90331a557eed9be4d32e899fd4 331 Gene3D G3DSA:3.40.190.10 28 134 1.4E-16 T 28-03-2018 A21D_RS12465 6a19de90331a557eed9be4d32e899fd4 331 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 34 330 8.0E-57 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 A21D_RS12465 6a19de90331a557eed9be4d32e899fd4 331 SUPERFAMILY SSF53850 31 264 1.2E-40 T 28-03-2018 A21D_RS12465 6a19de90331a557eed9be4d32e899fd4 331 Gene3D G3DSA:3.40.190.10 135 331 1.3E-28 T 28-03-2018 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 SUPERFAMILY SSF46785 6 83 2.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 Gene3D G3DSA:1.10.10.10 2 73 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 Pfam PF07702 UTRA domain 97 232 9.7E-25 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 5.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 5.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 SMART SM00345 14 73 9.4E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 SMART SM00866 95 233 4.1E-19 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 SUPERFAMILY SSF64288 62 240 4.55E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS17640 840aff0f78b097d20f775bd25826b469 241 Gene3D G3DSA:3.40.1410.10 74 241 1.4E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 SUPERFAMILY SSF52518 11 336 1.2E-114 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 341 1.7E-146 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Pfam PF02780 Transketolase, C-terminal domain 556 658 8.8E-11 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Gene3D G3DSA:3.40.50.970 1 367 1.4E-105 T 28-03-2018 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Gene3D G3DSA:3.40.50.970 368 544 1.3E-42 T 28-03-2018 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 SMART SM00861 357 527 2.4E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Pfam PF02779 Transketolase, pyrimidine binding domain 358 525 2.8E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 SUPERFAMILY SSF52518 344 528 6.18E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 12 665 9.5E-276 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 Gene3D G3DSA:3.40.50.920 545 665 7.8E-30 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS19425 42d6fa82a3087c63eb2853d1622427a1 666 SUPERFAMILY SSF52922 536 666 1.83E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 1.6E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 SUPERFAMILY SSF55973 5 111 8.63E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 1.2E-47 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Gene3D G3DSA:3.30.300.10 13 145 7.1E-43 T 28-03-2018 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 57.605 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 SUPERFAMILY SSF55973 125 246 1.1E-50 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 PIRSF PIRSF000497 1 398 3.1E-175 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 2.3E-181 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Gene3D G3DSA:3.30.300.10 146 247 1.2E-45 T 28-03-2018 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Gene3D G3DSA:3.30.300.10 260 399 1.1E-45 T 28-03-2018 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 4.7E-43 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14150 d3fa4033ba2f569a0324c288247b8154 401 SUPERFAMILY SSF55973 247 395 1.53E-68 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 Gene3D G3DSA:3.40.50.10490 1 62 4.2E-10 T 28-03-2018 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 Gene3D G3DSA:3.40.50.10490 63 207 1.7E-43 T 28-03-2018 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 SUPERFAMILY SSF53697 6 447 5.99E-141 T 28-03-2018 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 Gene3D G3DSA:3.40.50.10490 208 434 4.0E-78 T 28-03-2018 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 Pfam PF00342 Phosphoglucose isomerase 76 426 6.9E-25 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 4.9E-29 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.829 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS14005 3c737e24b575732ad0ca9820679b573d 448 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 ProSitePatterns PS00855 Signal peptidases II signature. 93 105 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 TIGRFAM TIGR00077 lspA: signal peptidase II 2 153 5.8E-44 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 3.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 90 105 3.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 46 54 3.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 151 16.923 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS18310 82790750d2e521da1c7a15c7d318490a 156 Pfam PF01252 Signal peptidase (SPase) II 7 145 5.4E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A21D_RS15930 e4bd7531fbeecf9759d7248aa3f5b1b1 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS15930 e4bd7531fbeecf9759d7248aa3f5b1b1 536 Pfam PF13751 Transposase DDE domain 393 518 2.9E-31 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS15930 e4bd7531fbeecf9759d7248aa3f5b1b1 536 Gene3D G3DSA:3.90.350.10 230 497 1.9E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PRINTS PR01950 LanC-like protein superfamily signature 666 684 2.3E-15 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PRINTS PR01950 LanC-like protein superfamily signature 975 992 2.3E-15 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PRINTS PR01950 LanC-like protein superfamily signature 761 776 2.3E-15 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PRINTS PR01950 LanC-like protein superfamily signature 878 898 2.3E-15 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PRINTS PR01950 LanC-like protein superfamily signature 819 835 2.3E-15 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 Pfam PF13575 Domain of unknown function (DUF4135) 176 539 4.6E-79 T 28-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 SMART SM01260 663 1005 4.9E-41 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 PIRSF PIRSF037228 15 1004 7.6E-174 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 SUPERFAMILY SSF158745 657 1003 2.35E-61 T 28-03-2018 A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 Gene3D G3DSA:1.50.10.10 594 733 3.8E-5 T 28-03-2018 A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 Pfam PF05147 Lanthionine synthetase C-like protein 665 1002 1.1E-53 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 Gene3D G3DSA:1.50.10.10 734 890 7.9E-6 T 28-03-2018 A21D_RS07790 afd276a63bf38fe071ed66cf76e7b607 1005 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 112 995 1.8E-186 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 SUPERFAMILY SSF50022 428 507 1.44E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 Gene3D G3DSA:3.50.50.60 20 408 6.1E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 Gene3D G3DSA:2.102.10.10 409 511 1.6E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 Pfam PF00355 Rieske [2Fe-2S] domain 432 507 4.4E-14 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 481 493 1.5E-6 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 460 471 1.5E-6 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 493 505 1.5E-6 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 SUPERFAMILY SSF51905 34 254 4.14E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 SUPERFAMILY SSF51905 304 384 4.14E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16925 57de3e8e1a890dee741c8538ea6e5805 514 Pfam PF01266 FAD dependent oxidoreductase 34 378 1.0E-35 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 SMART SM00421 154 211 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 208 3.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 Gene3D G3DSA:1.10.10.10 127 216 9.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 Pfam PF00072 Response regulator receiver domain 4 113 5.0E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 SUPERFAMILY SSF52172 1 128 3.73E-13 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 Gene3D G3DSA:3.40.50.2300 1 126 1.2E-15 T 28-03-2018 A21D_RS10755 65114be8fcc61adaa9693ff31e56c3c4 224 SUPERFAMILY SSF46894 146 206 4.42E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Gene3D G3DSA:3.40.50.980 12 168 1.9E-29 T 28-03-2018 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Pfam PF00501 AMP-binding enzyme 15 408 2.2E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Gene3D G3DSA:2.30.38.10 319 401 2.0E-18 T 28-03-2018 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 SUPERFAMILY SSF56801 6 503 6.15E-110 T 28-03-2018 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Gene3D G3DSA:3.40.50.980 169 318 1.2E-27 T 28-03-2018 A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 1.3E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS04975 95a5adfd51430787064153b3f34974e2 508 Gene3D G3DSA:3.30.300.30 403 508 1.9E-22 T 28-03-2018 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 354 48.906 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 Gene3D G3DSA:3.40.718.10 1 358 1.3E-126 T 28-03-2018 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 350 2.1E-134 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 SUPERFAMILY SSF53659 4 354 1.44E-120 T 28-03-2018 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 SMART SM01329 4 350 1.5E-191 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A21D_RS01430 295e336d5a44166bac1e01bc4664cfa7 368 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 349 3.4E-155 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 8.6E-26 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 7.6E-27 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 7.6E-27 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 7.6E-27 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 7.6E-27 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 SUPERFAMILY SSF48557 3 427 1.23E-136 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 Gene3D G3DSA:1.10.40.30 349 428 1.5E-28 T 28-03-2018 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 SMART SM00998 349 429 1.3E-39 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 Pfam PF00206 Lyase 7 285 2.2E-72 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 Gene3D G3DSA:1.20.200.10 93 348 8.6E-81 T 28-03-2018 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 Gene3D G3DSA:1.10.275.10 2 92 1.5E-25 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 8.6E-179 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 2.3E-9 T 28-03-2018 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 2.3E-9 T 28-03-2018 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.3E-9 T 28-03-2018 A21D_RS10930 bcc7237de57b13475780d6d86c38561a 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 2.3E-9 T 28-03-2018 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.0E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 Gene3D G3DSA:3.40.190.10 178 267 2.7E-25 T 28-03-2018 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 SUPERFAMILY SSF46785 1 84 1.21E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 Gene3D G3DSA:1.10.10.10 1 83 6.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 SUPERFAMILY SSF53850 89 296 6.05E-41 T 28-03-2018 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 Pfam PF03466 LysR substrate binding domain 89 291 1.5E-44 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12595 df1ae096358375ffdd69cec6d933c348 301 Gene3D G3DSA:3.40.190.10 88 177 2.5E-20 T 28-03-2018 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 Gene3D G3DSA:3.40.50.150 237 451 1.4E-57 T 28-03-2018 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 11 448 1.4E-133 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 Pfam PF01189 16S rRNA methyltransferase RsmB/F 246 446 1.0E-53 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 SUPERFAMILY SSF48013 6 154 7.46E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 Gene3D G3DSA:1.10.940.10 1 144 1.3E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 SUPERFAMILY SSF53335 138 448 1.55E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 430 447 7.2E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 7.2E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 7.2E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 7.2E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 7.2E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 Pfam PF01029 NusB family 6 128 1.7E-28 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS18190 12052ac8838ae8a14e26562c12cd57be 451 Gene3D G3DSA:3.30.70.1170 170 236 1.4E-10 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 663 5.7E-13 T 28-03-2018 IPR001357 BRCT domain A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 PIRSF PIRSF001604 1 670 1.7E-268 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SMART SM00292 591 668 2.2E-14 T 28-03-2018 IPR001357 BRCT domain A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:3.30.470.30 119 235 7.1E-53 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 2.6E-33 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF12826 Helix-hairpin-helix motif 505 567 1.2E-23 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:1.10.150.20 427 500 1.3E-28 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:1.10.150.20 501 566 5.4E-23 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SMART SM00532 5 443 1.5E-283 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Hamap MF_01588 DNA ligase [ligA]. 4 665 54.195 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SUPERFAMILY SSF50249 313 396 2.23E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF14520 Helix-hairpin-helix domain 443 495 8.3E-6 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SMART SM00278 475 494 0.95 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SMART SM00278 539 558 4.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SMART SM00278 441 460 200.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 7.5E-135 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SUPERFAMILY SSF52113 591 667 2.06E-18 T 28-03-2018 IPR001357 BRCT domain A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:3.30.1490.70 236 317 1.3E-31 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:3.40.50.10190 567 669 1.8E-22 T 28-03-2018 IPR001357 BRCT domain A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 403 429 1.1E-10 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:2.40.50.140 318 386 3.4E-32 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 661 3.4E-277 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SUPERFAMILY SSF56091 2 312 1.56E-125 T 28-03-2018 A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 SUPERFAMILY SSF47781 399 580 1.41E-62 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS11005 bb5c882bed57f9390fff1c2e971e0eac 672 Gene3D G3DSA:1.10.287.610 1 69 8.9E-25 T 28-03-2018 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 SMART SM00072 5 187 6.5E-65 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 36.524 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 7 184 4.6E-74 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 Gene3D G3DSA:3.40.50.300 1 51 3.0E-7 T 28-03-2018 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 SUPERFAMILY SSF52540 4 190 3.83E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 Gene3D G3DSA:3.30.63.10 52 83 1.5E-21 T 28-03-2018 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 Gene3D G3DSA:3.40.50.300 84 187 1.8E-29 T 28-03-2018 A21D_RS18215 ce3aee6ece9e320119b69eb783094ca1 205 Pfam PF00625 Guanylate kinase 9 185 1.3E-46 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 SUPERFAMILY SSF54106 75 117 1.96E-11 T 28-03-2018 IPR018392 LysM domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 SUPERFAMILY SSF50685 217 257 1.05E-7 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Pfam PF06725 3D domain 216 276 3.7E-21 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Gene3D G3DSA:3.10.350.10 21 72 2.0E-13 T 28-03-2018 A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Pfam PF01476 LysM domain 76 116 2.4E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Pfam PF01476 LysM domain 27 68 1.4E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 SUPERFAMILY SSF54106 26 68 3.79E-10 T 28-03-2018 IPR018392 LysM domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Gene3D G3DSA:2.40.40.10 104 276 1.8E-43 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 Gene3D G3DSA:3.10.350.10 73 103 6.4E-12 T 28-03-2018 A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 SMART SM00257 75 118 3.1E-14 T 28-03-2018 IPR018392 LysM domain A21D_RS09035 586e46a691e4ab98250c3aea05aa645e 277 SMART SM00257 26 69 2.7E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS17585 31d779e12ea9aba61050e4c5572bedae 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 1.8E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A21D_RS17585 31d779e12ea9aba61050e4c5572bedae 192 PIRSF PIRSF000847 1 192 4.3E-55 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A21D_RS17585 31d779e12ea9aba61050e4c5572bedae 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A21D_RS17585 31d779e12ea9aba61050e4c5572bedae 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 189 7.2E-62 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A21D_RS18570 bfce98d945186ed175b53e81a20196c1 396 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 318 342 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A21D_RS18570 bfce98d945186ed175b53e81a20196c1 396 Pfam PF01098 Cell cycle protein 12 360 4.0E-107 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A21D_RS01155 fcdb4efc1b42e5f0b2d4349b127eb3a7 238 Gene3D G3DSA:3.40.50.880 1 238 4.2E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS01155 fcdb4efc1b42e5f0b2d4349b127eb3a7 238 SUPERFAMILY SSF52317 24 237 4.28E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS01155 fcdb4efc1b42e5f0b2d4349b127eb3a7 238 Pfam PF07722 Peptidase C26 3 213 2.9E-66 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.0E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Gene3D G3DSA:2.40.30.10 302 395 4.5E-33 T 28-03-2018 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 7.9E-62 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 147 2.6E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Gene3D G3DSA:3.40.50.300 1 75 6.1E-11 T 28-03-2018 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Gene3D G3DSA:3.40.50.300 76 192 2.8E-32 T 28-03-2018 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 4.0E-19 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.7E-232 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 SUPERFAMILY SSF50465 300 395 1.61E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 SUPERFAMILY SSF50447 204 303 1.77E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 SUPERFAMILY SSF52540 6 220 3.02E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.502 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 Gene3D G3DSA:2.40.30.10 193 300 1.1E-32 T 28-03-2018 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 PRINTS PR00315 GTP-binding elongation factor signature 79 89 8.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 PRINTS PR00315 GTP-binding elongation factor signature 59 67 8.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 PRINTS PR00315 GTP-binding elongation factor signature 132 141 8.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS06385 5b7acd1f396513fffca5a7538591a461 396 PRINTS PR00315 GTP-binding elongation factor signature 95 106 8.1E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS02765 713fc5891ce2b189106f057417ae1158 180 Gene3D G3DSA:3.40.630.30 1 179 7.5E-23 T 28-03-2018 A21D_RS02765 713fc5891ce2b189106f057417ae1158 180 Pfam PF13302 Acetyltransferase (GNAT) domain 7 154 6.3E-22 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS02765 713fc5891ce2b189106f057417ae1158 180 SUPERFAMILY SSF55729 3 175 6.49E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS16875 c10fff43fc0a6a4aa329ba1d0b60a21f 67 Pfam PF02416 mttA/Hcf106 family 5 57 1.1E-20 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A21D_RS16875 c10fff43fc0a6a4aa329ba1d0b60a21f 67 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 6.8E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS16875 c10fff43fc0a6a4aa329ba1d0b60a21f 67 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 6.8E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS16875 c10fff43fc0a6a4aa329ba1d0b60a21f 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 65 18.211 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS16875 c10fff43fc0a6a4aa329ba1d0b60a21f 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 49 2.3E-19 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS14710 d630f35f85fa0230712cb01be742cd28 208 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 108 136 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A21D_RS14710 d630f35f85fa0230712cb01be742cd28 208 Pfam PF01464 Transglycosylase SLT domain 90 198 4.9E-33 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A21D_RS14710 d630f35f85fa0230712cb01be742cd28 208 SUPERFAMILY SSF53955 80 206 5.63E-49 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS14710 d630f35f85fa0230712cb01be742cd28 208 Gene3D G3DSA:1.10.530.10 35 208 6.9E-50 T 28-03-2018 A21D_RS10405 d7da2e4c795faebeea15a18b28bb050e 127 Gene3D G3DSA:1.10.720.10 71 116 5.7E-16 T 28-03-2018 A21D_RS10405 d7da2e4c795faebeea15a18b28bb050e 127 SUPERFAMILY SSF68912 71 122 3.92E-14 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 SMART SM00283 284 559 1.0E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 344 513 6.1E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 Gene3D G3DSA:1.10.287.950 317 552 2.7E-53 T 28-03-2018 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 Gene3D G3DSA:1.10.287.950 35 316 3.8E-6 T 28-03-2018 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 SUPERFAMILY SSF58104 228 257 1.44E-68 T 28-03-2018 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 SUPERFAMILY SSF58104 290 558 1.44E-68 T 28-03-2018 A21D_RS10790 6053706e55da6dde6e12c3752409ed9a 566 Pfam PF12729 Four helix bundle sensory module for signal transduction 9 128 2.5E-6 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A21D_RS10240 5a874aa04e1d8b2a32d531908f7a686d 148 Gene3D G3DSA:1.20.120.330 59 140 7.5E-4 T 28-03-2018 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 Gene3D G3DSA:3.40.630.10 1 286 1.1E-55 T 28-03-2018 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 379 8.3E-102 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 PIRSF PIRSF005962 1 393 2.7E-122 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 SUPERFAMILY SSF53187 6 203 2.39E-75 T 28-03-2018 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 SUPERFAMILY SSF53187 304 391 2.39E-75 T 28-03-2018 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 Pfam PF01546 Peptidase family M20/M25/M40 75 387 3.3E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 Pfam PF07687 Peptidase dimerisation domain 191 287 1.0E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS01200 0640ca944d3ae006611718b4dcc17a52 398 SUPERFAMILY SSF55031 188 305 2.09E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:3.30.70.1430 40 141 1.2E-26 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:1.20.1640.10 264 490 1.2E-45 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:1.20.1640.10 792 1010 4.2E-47 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 1.7E-263 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:3.30.2090.10 703 791 4.3E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82714 704 787 1.03E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:3.30.70.1430 553 658 5.5E-16 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82693 265 321 3.14E-16 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82693 135 179 3.14E-16 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 538 555 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.8E-44 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82693 40 134 4.53E-24 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82866 288 486 5.49E-44 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82693 552 653 1.1E-10 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82714 180 262 2.22E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 SUPERFAMILY SSF82866 788 1010 2.35E-55 T 28-03-2018 A21D_RS04415 74bcfdec2c6daf3e913a17e148b55d36 1022 Gene3D G3DSA:3.30.2090.10 178 263 5.3E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 SUPERFAMILY SSF47413 1 59 2.09E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 Gene3D G3DSA:1.10.260.40 2 57 1.8E-18 T 28-03-2018 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 SUPERFAMILY SSF53822 61 327 6.52E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 Pfam PF13377 Periplasmic binding protein-like domain 166 326 5.3E-37 T 28-03-2018 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 SMART SM00354 1 71 2.6E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 Gene3D G3DSA:3.40.50.2300 58 164 8.2E-25 T 28-03-2018 A21D_RS04895 97cb2ac5cd149a0d1718fb5847510371 343 Gene3D G3DSA:3.40.50.2300 165 329 3.6E-51 T 28-03-2018 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 27 2.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 1.9E-7 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 1.9E-7 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 SUPERFAMILY SSF54523 8 71 9.42E-15 T 28-03-2018 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 Gene3D G3DSA:3.30.700.10 8 98 7.0E-12 T 28-03-2018 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 PIRSF PIRSF029928 1 99 4.4E-35 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 A21D_RS15970 06bb65f24a17546b598e5e6c8c068d3b 99 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 5.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 SUPERFAMILY SSF51735 3 245 6.57E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 Gene3D G3DSA:3.40.50.720 1 248 1.1E-32 T 28-03-2018 A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS12930 cb6e08bb44f3369effdedaae4d956253 252 Pfam PF00106 short chain dehydrogenase 4 201 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 SMART SM00529 24 123 4.2E-39 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 59 1.3E-24 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 124 1.5E-17 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 SUPERFAMILY SSF46785 3 62 1.78E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 41.804 T 28-03-2018 IPR022897 Transcription regulator MntR A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 Gene3D G3DSA:1.10.10.10 2 72 5.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 Gene3D G3DSA:1.10.60.10 75 136 2.6E-20 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A21D_RS16020 f8b5fa82f1403ed784c730145ab48154 143 SUPERFAMILY SSF47979 63 128 3.14E-18 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 SUPERFAMILY SSF55154 5 83 2.29E-28 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 SUPERFAMILY SSF55154 114 185 2.29E-28 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 Pfam PF01928 CYTH domain 4 185 1.5E-29 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 Gene3D G3DSA:2.40.320.10 5 188 1.8E-32 T 28-03-2018 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 SMART SM01118 4 188 7.4E-16 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A21D_RS13505 83842b7a6b739af37a0991190dd0591c 188 PIRSF PIRSF012526 1 188 1.1E-64 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK A21D_RS04190 0a62b86c503356bbbfe69fd2f7f80c61 263 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04190 0a62b86c503356bbbfe69fd2f7f80c61 263 SUPERFAMILY SSF52540 33 235 3.97E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04190 0a62b86c503356bbbfe69fd2f7f80c61 263 Pfam PF00005 ABC transporter 40 171 1.9E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04190 0a62b86c503356bbbfe69fd2f7f80c61 263 Gene3D G3DSA:3.40.50.300 1 260 1.3E-48 T 28-03-2018 A21D_RS04190 0a62b86c503356bbbfe69fd2f7f80c61 263 SMART SM00382 49 229 2.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 SUPERFAMILY SSF52440 1 113 5.47E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Gene3D G3DSA:3.30.1490.20 124 209 1.1E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 SUPERFAMILY SSF51246 332 445 4.29E-47 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Gene3D G3DSA:3.30.470.20 210 446 2.6E-102 T 28-03-2018 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 3.6E-43 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 2.1E-83 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 445 1.1E-235 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Gene3D G3DSA:3.40.50.20 1 123 6.1E-53 T 28-03-2018 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 SMART SM00878 337 443 8.7E-68 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 SUPERFAMILY SSF56059 83 349 1.52E-68 T 28-03-2018 A21D_RS16095 675151e6ea5aa98954b67367217b0293 453 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 2.5E-46 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A21D_RS01820 f77a90c1832b1f2b904085d35bcfd8cc 333 Gene3D G3DSA:3.20.20.70 12 331 3.4E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS01820 f77a90c1832b1f2b904085d35bcfd8cc 333 Pfam PF03060 Nitronate monooxygenase 98 319 2.5E-45 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A21D_RS01820 f77a90c1832b1f2b904085d35bcfd8cc 333 Pfam PF03060 Nitronate monooxygenase 20 89 1.0E-13 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A21D_RS01820 f77a90c1832b1f2b904085d35bcfd8cc 333 SUPERFAMILY SSF51412 17 327 1.83E-62 T 28-03-2018 A21D_RS03570 d9873c3b0edf5a2cd289308186a70f00 268 SUPERFAMILY SSF53613 5 260 3.27E-80 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03570 d9873c3b0edf5a2cd289308186a70f00 268 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 259 4.6E-103 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03570 d9873c3b0edf5a2cd289308186a70f00 268 Gene3D G3DSA:3.40.1190.20 1 268 1.1E-59 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03570 d9873c3b0edf5a2cd289308186a70f00 268 Pfam PF08543 Phosphomethylpyrimidine kinase 14 257 2.5E-99 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 Gene3D G3DSA:3.20.10.10 176 339 6.3E-50 T 28-03-2018 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 SUPERFAMILY SSF56752 14 353 2.09E-114 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 Pfam PF01063 Amino-transferase class IV 70 312 7.9E-33 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 PIRSF PIRSF006468 1 358 2.2E-128 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 Gene3D G3DSA:3.30.470.10 1 175 4.0E-65 T 28-03-2018 A21D_RS12480 77a22ca43141e58e01a6b053f1835d16 364 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 356 2.6E-121 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A21D_RS09890 20c9bf6a1ff305a3445a90900b9557bb 200 Pfam PF03413 Peptidase propeptide and YPEB domain 35 88 0.006 T 28-03-2018 IPR025711 PepSY domain A21D_RS09890 20c9bf6a1ff305a3445a90900b9557bb 200 Pfam PF03413 Peptidase propeptide and YPEB domain 138 192 1.0E-12 T 28-03-2018 IPR025711 PepSY domain A21D_RS09890 20c9bf6a1ff305a3445a90900b9557bb 200 Gene3D G3DSA:3.10.450.40 34 90 0.017 T 28-03-2018 A21D_RS09890 20c9bf6a1ff305a3445a90900b9557bb 200 Gene3D G3DSA:3.10.450.40 138 195 6.5E-17 T 28-03-2018 A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 SUPERFAMILY SSF55060 161 281 1.77E-30 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 SUPERFAMILY SSF54211 2 157 1.14E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 Pfam PF08544 GHMP kinases C terminal 198 272 5.5E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 34.586 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 Pfam PF00288 GHMP kinases N terminal domain 86 143 3.1E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 283 1.3E-92 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 Gene3D G3DSA:3.30.230.10 4 159 4.3E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 Gene3D G3DSA:3.30.70.890 161 282 7.9E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS06775 27d630636c9219ee9e388d8aae6a2a3a 283 PIRSF PIRSF010376 1 282 2.3E-92 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A21D_RS19300 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS19300 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS19300 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS19300 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12580 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12580 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS12580 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS12580 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS09895 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS09895 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS09895 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS09895 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS03950 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS03950 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS03950 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS03950 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS15900 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS15900 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS15900 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS15900 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS07290 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS07290 4d0bdd317444061afad72f585833a9f5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS07290 4d0bdd317444061afad72f585833a9f5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS07290 4d0bdd317444061afad72f585833a9f5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS07220 baa77e6ba5ca39001c08ef1a12f90982 72 SUPERFAMILY SSF55174 3 65 7.3E-17 T 28-03-2018 A21D_RS07220 baa77e6ba5ca39001c08ef1a12f90982 72 Pfam PF13275 S4 domain 6 63 5.9E-25 T 28-03-2018 A21D_RS07220 baa77e6ba5ca39001c08ef1a12f90982 72 Gene3D G3DSA:3.10.290.10 1 69 5.2E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS07220 baa77e6ba5ca39001c08ef1a12f90982 72 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 63 8.9E-28 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 Gene3D G3DSA:3.30.1130.10 1 119 8.7E-33 T 28-03-2018 A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 4.8E-36 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 Pfam PF02152 Dihydroneopterin aldolase 4 115 7.4E-30 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 SUPERFAMILY SSF55620 2 118 3.61E-36 T 28-03-2018 A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 6.5E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A21D_RS06630 f386faf432b7e5c164e25164ab246edb 121 SMART SM00905 4 117 9.8E-42 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A21D_RS12045 4758704209a92e9af2c317f3db4a6bbe 208 Pfam PF02581 Thiamine monophosphate synthase 8 184 4.8E-34 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS12045 4758704209a92e9af2c317f3db4a6bbe 208 SUPERFAMILY SSF51391 5 202 7.46E-41 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS12045 4758704209a92e9af2c317f3db4a6bbe 208 Gene3D G3DSA:3.20.20.70 4 202 5.8E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.807 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 3.9E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 2.6E-54 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 SUPERFAMILY SSF52080 4 143 1.57E-48 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 Gene3D G3DSA:3.100.10.10 44 146 5.2E-32 T 28-03-2018 A21D_RS06280 3fe0a25a2ce4ee5f849298a6a487b9c4 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS01490 d79fcb78b0bd5308aa43525ad168bf74 139 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 1 138 42.415 T 28-03-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 A21D_RS01490 d79fcb78b0bd5308aa43525ad168bf74 139 Gene3D G3DSA:3.10.180.10 1 135 6.8E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS01490 d79fcb78b0bd5308aa43525ad168bf74 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 3.1E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS01490 d79fcb78b0bd5308aa43525ad168bf74 139 SUPERFAMILY SSF54593 1 129 1.48E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS11460 440943cd5c18255c7af3865a97606967 282 SUPERFAMILY SSF140959 25 281 7.59E-99 T 28-03-2018 A21D_RS11460 440943cd5c18255c7af3865a97606967 282 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 20 282 40.108 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A21D_RS11460 440943cd5c18255c7af3865a97606967 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 187 281 5.6E-26 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A21D_RS11460 440943cd5c18255c7af3865a97606967 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 151 6.7E-43 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A21D_RS11460 440943cd5c18255c7af3865a97606967 282 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 19 282 4.9E-127 T 28-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 SUPERFAMILY SSF48150 1 211 1.88E-71 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Pfam PF00633 Helix-hairpin-helix motif 101 128 4.3E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Hamap MF_00942 Endonuclease III [nth]. 1 211 37.94 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 1.2E-23 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 PIRSF PIRSF001435 1 214 7.5E-58 T 28-03-2018 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Gene3D G3DSA:1.10.340.30 22 118 7.7E-27 T 28-03-2018 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 SMART SM00478 39 187 2.7E-65 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Gene3D G3DSA:1.10.1670.10 119 220 9.6E-35 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.3E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 TIGRFAM TIGR01083 nth: endonuclease III 5 196 8.6E-85 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A21D_RS16760 e2ef339487e3f17361e0a8563c35d852 220 SMART SM00525 188 208 0.0013 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 186 295 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 296 7.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 277 7.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 243 253 7.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 225 239 7.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 SUPERFAMILY SSF55874 135 295 3.27E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 Gene3D G3DSA:3.30.565.10 154 298 7.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 Gene3D G3DSA:1.10.287.130 67 153 1.4E-4 T 28-03-2018 A21D_RS11740 8d67b9e8add22dfaf9f51ed57bd29beb 298 SMART SM00387 186 298 4.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 Hamap MF_01987 Ribokinase [rbsK]. 4 289 25.084 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 234 247 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 Pfam PF00294 pfkB family carbohydrate kinase 4 282 2.6E-65 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 Gene3D G3DSA:3.40.1190.20 2 295 1.3E-76 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 PRINTS PR00990 Ribokinase signature 205 216 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 PRINTS PR00990 Ribokinase signature 174 189 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 PRINTS PR00990 Ribokinase signature 35 54 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 PRINTS PR00990 Ribokinase signature 106 119 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 PRINTS PR00990 Ribokinase signature 8 29 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 287 4.4E-96 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A21D_RS10665 249ec7cfac1b09f25a113d50fb93ca94 295 SUPERFAMILY SSF53613 4 283 1.17E-76 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08280 47a969aecf6bc9e4d06ff52436feec04 409 SUPERFAMILY SSF53098 63 342 3.49E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS08280 47a969aecf6bc9e4d06ff52436feec04 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS08280 47a969aecf6bc9e4d06ff52436feec04 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.7E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS08280 47a969aecf6bc9e4d06ff52436feec04 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS10600 47a969aecf6bc9e4d06ff52436feec04 409 SUPERFAMILY SSF53098 63 342 3.49E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS10600 47a969aecf6bc9e4d06ff52436feec04 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS10600 47a969aecf6bc9e4d06ff52436feec04 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.7E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS10600 47a969aecf6bc9e4d06ff52436feec04 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 Gene3D G3DSA:1.10.10.10 11 72 3.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 11 64 4.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 SUPERFAMILY SSF46894 7 71 4.08E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS14845 e322bcbeb9554cd7861a01c0ea07c7e1 74 SMART SM00421 9 66 1.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 Pfam PF00122 E1-E2 ATPase 185 366 9.9E-50 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 Gene3D G3DSA:3.40.1110.10 402 510 6.0E-32 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 540 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 583 602 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 618 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 386 400 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 519 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 236 250 4.7E-29 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF81665 126 189 9.94E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF81665 287 378 9.94E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF81665 632 651 9.94E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 Gene3D G3DSA:3.40.50.1000 511 649 2.7E-42 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 106 692 1.0E-192 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 Pfam PF00702 haloacid dehalogenase-like hydrolase 383 597 8.0E-41 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 151 689 1.4E-120 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF81653 196 286 1.7E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 Gene3D G3DSA:1.20.1110.10 92 401 3.5E-38 T 28-03-2018 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF56784 480 688 3.79E-58 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 SUPERFAMILY SSF56784 385 404 3.79E-58 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 161 662 1.8E-87 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 124 690 3.0E-193 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 388 394 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 555 571 1.1E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 583 599 1.1E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS03915 a7967be9f4738616ed962b5b679090b2 693 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 614 639 1.1E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS16565 802dc978e3cbf741d18f8323ac371478 65 Pfam PF10966 Protein of unknown function (DUF2768) 7 63 2.1E-20 T 28-03-2018 IPR020076 Protein of unknown function DUF2768 A21D_RS16565 802dc978e3cbf741d18f8323ac371478 65 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 2 64 2.0E-4 T 28-03-2018 IPR020076 Protein of unknown function DUF2768 A21D_RS07245 e1998438b323bd8bbb1d075b89e44f7e 255 PRINTS PR00701 60kDa inner membrane protein signature 209 232 9.3E-16 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A21D_RS07245 e1998438b323bd8bbb1d075b89e44f7e 255 PRINTS PR00701 60kDa inner membrane protein signature 124 147 9.3E-16 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A21D_RS07245 e1998438b323bd8bbb1d075b89e44f7e 255 Pfam PF02096 60Kd inner membrane protein 59 243 2.2E-61 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A21D_RS07245 e1998438b323bd8bbb1d075b89e44f7e 255 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 243 8.2E-68 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A21D_RS07245 e1998438b323bd8bbb1d075b89e44f7e 255 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 246 33.381 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes A21D_RS00770 6088c48941a53315e980de2bf22df621 297 PIRSF PIRSF003097 1 297 7.4E-84 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 A21D_RS00770 6088c48941a53315e980de2bf22df621 297 Pfam PF02687 FtsX-like permease family 201 288 2.0E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS09265 7d4a40a611947ff7586c6b14d585bda9 77 Gene3D G3DSA:3.10.20.30 2 77 1.7E-18 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS09265 7d4a40a611947ff7586c6b14d585bda9 77 SUPERFAMILY SSF54285 1 77 1.2E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A21D_RS09265 7d4a40a611947ff7586c6b14d585bda9 77 Pfam PF02597 ThiS family 4 77 1.4E-17 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A21D_RS09265 7d4a40a611947ff7586c6b14d585bda9 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 5.1E-24 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 Gene3D G3DSA:3.40.50.300 1 286 1.9E-133 T 28-03-2018 A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 2.1E-259 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 Gene3D G3DSA:3.40.50.880 287 535 4.3E-73 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 SUPERFAMILY SSF52540 1 270 2.0E-126 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 SUPERFAMILY SSF52317 290 534 4.74E-82 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 Pfam PF00117 Glutamine amidotransferase class-I 302 526 3.3E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 Hamap MF_01227 CTP synthase [pyrG]. 2 533 52.591 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A21D_RS04700 61c66a658ef51c8c8042ac248c71c019 535 Pfam PF06418 CTP synthase N-terminus 3 267 1.4E-129 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A21D_RS15140 bc59c2269514e7b734abe7796756639c 357 SUPERFAMILY SSF56112 17 150 3.5E-16 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS15140 bc59c2269514e7b734abe7796756639c 357 SUPERFAMILY SSF56112 189 301 3.5E-16 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS15140 bc59c2269514e7b734abe7796756639c 357 Gene3D G3DSA:3.90.1200.10 95 334 1.0E-11 T 28-03-2018 A21D_RS15140 bc59c2269514e7b734abe7796756639c 357 Pfam PF01633 Choline/ethanolamine kinase 119 276 2.2E-7 T 28-03-2018 A21D_RS15140 bc59c2269514e7b734abe7796756639c 357 Gene3D G3DSA:3.30.200.20 7 94 9.3E-7 T 28-03-2018 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 SUPERFAMILY SSF64288 60 233 1.44E-38 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 Gene3D G3DSA:3.40.1410.10 77 236 4.1E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 SMART SM00345 11 70 1.9E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 5.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 Gene3D G3DSA:1.10.10.10 1 72 9.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 SUPERFAMILY SSF46785 3 74 1.78E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 8.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 8.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 Pfam PF07702 UTRA domain 92 228 2.6E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS08430 b49e6b026db15b9030988b25862e320f 236 SMART SM00866 91 229 1.1E-26 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Gene3D G3DSA:3.30.565.10 1 195 1.5E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 128 1.0E-13 T 28-03-2018 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 SUPERFAMILY SSF54211 188 325 1.71E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 207 324 5.9E-38 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 305 4.9E-102 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 SMART SM01340 207 325 2.2E-55 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Pfam PF08676 MutL C terminal dimerisation domain 451 592 5.2E-46 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 632 27.232 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 SUPERFAMILY SSF55874 2 212 2.29E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 SMART SM00853 450 592 2.0E-53 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 Gene3D G3DSA:3.30.230.10 196 325 1.1E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS17535 fbbb0bdfd31c0e37f9d5b866d5798e79 636 SUPERFAMILY SSF118116 446 634 6.67E-57 T 28-03-2018 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Pfam PF17203 Single cache domain 3 50 181 3.8E-27 T 28-03-2018 IPR033463 Single cache domain 3 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Gene3D G3DSA:1.10.287.130 329 389 1.8E-17 T 28-03-2018 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SUPERFAMILY SSF55874 398 542 5.24E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Gene3D G3DSA:3.30.565.10 390 544 7.4E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 435 542 1.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SUPERFAMILY SSF103190 49 180 3.18E-38 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Gene3D G3DSA:3.30.450.20 43 183 2.3E-27 T 28-03-2018 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Gene3D G3DSA:3.30.450.20 228 328 1.1E-8 T 28-03-2018 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SUPERFAMILY SSF55890 336 421 1.57E-12 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SMART SM00091 225 294 0.007 T 28-03-2018 IPR000014 PAS domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 336 383 1.4E-9 T 28-03-2018 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SUPERFAMILY SSF55785 220 325 5.23E-6 T 28-03-2018 IPR000014 PAS domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 SMART SM00387 433 544 2.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 502 5.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 5.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 5.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS02500 c47b8a8d803879cf233950334a60f872 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 541 5.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 SUPERFAMILY SSF53163 6 366 1.49E-119 T 28-03-2018 IPR023430 Peptidase HybD-like domain A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 Gene3D G3DSA:3.40.50.1450 9 364 1.1E-121 T 28-03-2018 IPR023430 Peptidase HybD-like domain A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 PIRSF PIRSF019549 4 368 1.3E-172 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 TIGRFAM TIGR01441 GPR: GPR endopeptidase 11 367 3.2E-161 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 Pfam PF03418 Germination protease 18 367 1.6E-173 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 Hamap MF_00626 Germination protease [gpr]. 1 368 140.659 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A21D_RS15605 43130419ce4e3b5e7b28619e76d23bdc 368 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 11 350 1.0E-143 T 28-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A21D_RS05165 39db9edd297f927410436314787aa1c3 342 Pfam PF00144 Beta-lactamase 11 330 1.7E-41 T 28-03-2018 IPR001466 Beta-lactamase-related A21D_RS05165 39db9edd297f927410436314787aa1c3 342 Gene3D G3DSA:3.40.710.10 3 341 5.0E-59 T 28-03-2018 A21D_RS05165 39db9edd297f927410436314787aa1c3 342 SUPERFAMILY SSF56601 8 334 7.13E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS05040 1e6d43946946ccf4b9ca0721fb174fcf 377 Gene3D G3DSA:3.40.640.10 13 267 2.9E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS05040 1e6d43946946ccf4b9ca0721fb174fcf 377 Pfam PF00155 Aminotransferase class I and II 27 365 3.8E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS05040 1e6d43946946ccf4b9ca0721fb174fcf 377 Gene3D G3DSA:3.90.1150.10 268 375 1.4E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS05040 1e6d43946946ccf4b9ca0721fb174fcf 377 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 6 365 9.2E-150 T 28-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A21D_RS05040 1e6d43946946ccf4b9ca0721fb174fcf 377 SUPERFAMILY SSF53383 4 372 3.13E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS12400 7486389a70c7da7c933b689a51a56697 464 Gene3D G3DSA:3.40.309.10 250 444 5.5E-70 T 28-03-2018 A21D_RS12400 7486389a70c7da7c933b689a51a56697 464 SUPERFAMILY SSF53720 4 461 4.71E-158 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS12400 7486389a70c7da7c933b689a51a56697 464 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS12400 7486389a70c7da7c933b689a51a56697 464 Pfam PF00171 Aldehyde dehydrogenase family 3 458 3.5E-162 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS12400 7486389a70c7da7c933b689a51a56697 464 Gene3D G3DSA:3.40.605.10 2 249 1.4E-86 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Gene3D G3DSA:1.20.140.10 221 381 4.8E-52 T 28-03-2018 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Gene3D G3DSA:2.40.110.10 121 220 8.1E-38 T 28-03-2018 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 2.5E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 2.3E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 SUPERFAMILY SSF47203 229 379 5.8E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 3.6E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 Gene3D G3DSA:1.10.540.10 4 120 1.6E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12165 d0d1beb8d191eda845ffed5833240e25 385 SUPERFAMILY SSF56645 4 243 5.37E-84 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS15040 9b68ece43bf02f8c79d30def225c835c 354 SMART SM00909 245 334 1.5E-11 T 28-03-2018 IPR019606 GerMN domain A21D_RS15040 9b68ece43bf02f8c79d30def225c835c 354 SMART SM00909 92 183 2.7E-23 T 28-03-2018 IPR019606 GerMN domain A21D_RS15040 9b68ece43bf02f8c79d30def225c835c 354 Pfam PF10646 Sporulation and spore germination 218 327 1.3E-12 T 28-03-2018 IPR019606 GerMN domain A21D_RS15040 9b68ece43bf02f8c79d30def225c835c 354 Pfam PF10646 Sporulation and spore germination 67 178 2.0E-19 T 28-03-2018 IPR019606 GerMN domain A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 49 9.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 SUPERFAMILY SSF48498 78 186 6.43E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 Gene3D G3DSA:1.10.357.10 50 189 7.6E-12 T 28-03-2018 A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 Gene3D G3DSA:1.10.10.60 2 49 3.5E-13 T 28-03-2018 A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 SUPERFAMILY SSF46689 3 66 9.75E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS07430 32a01e84d9cca034b124d1700e1e086d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS13725 87c8bcbf38e196c9fed4cde8f12758c8 163 PIRSF PIRSF032285 1 162 2.8E-62 T 28-03-2018 IPR011235 MepB-like A21D_RS13725 87c8bcbf38e196c9fed4cde8f12758c8 163 Pfam PF08877 MepB protein 26 147 4.6E-48 T 28-03-2018 IPR011235 MepB-like A21D_RS12700 6c43d48adf83468fc16bc6971d7241a9 305 PIRSF PIRSF000196 1 305 3.7E-124 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A21D_RS12700 6c43d48adf83468fc16bc6971d7241a9 305 SUPERFAMILY SSF51730 37 300 1.26E-70 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS12700 6c43d48adf83468fc16bc6971d7241a9 305 Pfam PF01619 Proline dehydrogenase 44 298 4.5E-35 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A21D_RS12700 6c43d48adf83468fc16bc6971d7241a9 305 Gene3D G3DSA:3.20.20.220 10 302 2.2E-66 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 87 9.1E-32 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 SUPERFAMILY SSF55804 490 637 1.96E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 94 5.2E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 SUPERFAMILY SSF52794 2 103 8.37E-38 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 494 637 7.1E-37 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 Gene3D G3DSA:3.40.930.10 489 639 4.1E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 Pfam PF02378 Phosphotransferase system, EIIC 131 405 9.3E-23 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 115 460 9.1E-96 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 495 622 6.3E-42 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 Gene3D G3DSA:3.40.50.2300 2 100 2.9E-40 T 28-03-2018 A21D_RS12435 1cf437aeb83c706f3bc068a1b77017df 639 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 540 556 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS15410 e542d9f1108696417db886e069a22b0e 368 Pfam PF01594 AI-2E family transporter 19 349 1.1E-70 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Gene3D G3DSA:3.30.413.10 77 140 3.0E-4 T 28-03-2018 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 5.4E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 5.4E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 560 1.6E-262 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Gene3D G3DSA:3.30.413.10 427 563 1.7E-27 T 28-03-2018 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 74 135 5.9E-18 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 354 417 1.4E-12 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 571 57.143 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 SUPERFAMILY SSF56014 429 559 6.8E-35 T 28-03-2018 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 SUPERFAMILY SSF55124 348 422 3.27E-18 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Gene3D G3DSA:3.30.413.10 141 347 2.0E-53 T 28-03-2018 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 SUPERFAMILY SSF56014 146 345 5.76E-57 T 28-03-2018 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 431 557 0.0019 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 171 331 2.8E-48 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07455 b16ef1e8c5e0895b6cced3b5f7684527 571 SUPERFAMILY SSF55124 12 145 1.64E-34 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS03565 8b8cbe205006e12f2c11f41d1ceec402 164 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 6 160 3.8E-54 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW A21D_RS03565 8b8cbe205006e12f2c11f41d1ceec402 164 PIRSF PIRSF024534 1 164 2.9E-47 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW A21D_RS03565 8b8cbe205006e12f2c11f41d1ceec402 164 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 7 153 1.3E-51 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW A21D_RS01100 2184533fed1e3977cf5998ce0a620df3 280 SUPERFAMILY SSF161098 7 280 1.87E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01100 2184533fed1e3977cf5998ce0a620df3 280 Gene3D G3DSA:1.10.3720.10 1 267 3.1E-46 T 28-03-2018 A21D_RS01100 2184533fed1e3977cf5998ce0a620df3 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 271 1.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 SMART SM00382 83 221 5.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 46 60 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 124 138 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 265 277 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 189 206 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 206 225 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 138 157 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 86 101 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 PRINTS PR00819 CbxX/CfqX superfamily signature 168 180 8.9E-56 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 Gene3D G3DSA:3.40.50.300 15 217 9.9E-27 T 28-03-2018 A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 SUPERFAMILY SSF52540 39 304 1.13E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17515 e5afe4ef622938aa8f58ccdbc030888e 308 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 87 194 1.4E-20 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS14885 ae2b40d108a31ab8c897dba00b03cc7e 323 Gene3D G3DSA:3.30.420.10 148 318 4.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14885 ae2b40d108a31ab8c897dba00b03cc7e 323 SUPERFAMILY SSF53098 160 309 2.47E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14885 ae2b40d108a31ab8c897dba00b03cc7e 323 Gene3D G3DSA:1.10.10.60 3 47 6.6E-8 T 28-03-2018 A21D_RS14885 ae2b40d108a31ab8c897dba00b03cc7e 323 Pfam PF00665 Integrase core domain 161 265 1.3E-8 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 ProSitePatterns PS00216 Sugar transport proteins signature 1. 259 274 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 SUPERFAMILY SSF103473 8 380 2.22E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 Gene3D G3DSA:1.20.1250.20 195 390 2.0E-22 T 28-03-2018 A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 Pfam PF07690 Major Facilitator Superfamily 214 384 2.0E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 Gene3D G3DSA:1.20.1250.20 2 188 2.8E-22 T 28-03-2018 A21D_RS11580 c0aad6aed0732e7f832bf699e9ef7a8c 391 Pfam PF12832 MFS_1 like family 5 150 1.0E-7 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 SUPERFAMILY SSF51556 56 183 5.88E-15 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 SUPERFAMILY SSF51556 220 349 5.88E-15 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 PIRSF PIRSF038971 2 386 3.1E-89 T 28-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 Gene3D G3DSA:2.30.40.10 306 389 2.1E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 3 385 1.0E-132 T 28-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 SUPERFAMILY SSF51338 352 387 8.99E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 SUPERFAMILY SSF51338 2 55 8.99E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 Pfam PF01979 Amidohydrolase family 52 382 3.9E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 Gene3D G3DSA:2.30.40.10 1 59 7.6E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08245 ea1f35182983bc2b9bfa8e99a55272a9 393 Gene3D G3DSA:3.20.20.140 60 305 7.0E-12 T 28-03-2018 A21D_RS10055 8351fa4ed189cd54822e3803d75b4353 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 1 158 39.28 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A21D_RS10055 8351fa4ed189cd54822e3803d75b4353 160 Gene3D G3DSA:3.30.565.10 3 146 1.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10055 8351fa4ed189cd54822e3803d75b4353 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 3 148 1.9E-68 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A21D_RS10055 8351fa4ed189cd54822e3803d75b4353 160 SUPERFAMILY SSF55874 31 134 1.64E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10055 8351fa4ed189cd54822e3803d75b4353 160 Pfam PF13581 Histidine kinase-like ATPase domain 11 140 7.3E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16515 2571600192f9bc71edc22e8abc4e2f85 446 Pfam PF14620 YpeB sporulation 14 368 1.5E-117 T 28-03-2018 IPR014239 Spore germination YpeB GO:0009847 A21D_RS16515 2571600192f9bc71edc22e8abc4e2f85 446 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 436 2.0E-133 T 28-03-2018 IPR014239 Spore germination YpeB GO:0009847 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 Gene3D G3DSA:3.60.21.10 2 314 1.8E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 250 270 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 370 393 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 190 207 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 6 24 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 224 247 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 PRINTS PR01607 Apyrase family signature 460 479 8.2E-25 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 SUPERFAMILY SSF55816 312 522 1.03E-48 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 Pfam PF02872 5'-nucleotidase, C-terminal domain 316 486 4.5E-33 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 SUPERFAMILY SSF56300 5 314 1.9E-82 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 Gene3D G3DSA:3.90.780.10 315 526 4.8E-48 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS09905 0a1a1cd495e134331ef3d516f854b0d0 526 Pfam PF00149 Calcineurin-like phosphoesterase 13 241 1.8E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 SUPERFAMILY SSF56104 3 235 1.28E-78 T 28-03-2018 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 Gene3D G3DSA:3.30.200.20 5 93 3.3E-25 T 28-03-2018 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 Gene3D G3DSA:3.30.470.20 94 221 6.1E-48 T 28-03-2018 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 235 31.588 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 Pfam PF01259 SAICAR synthetase 6 231 2.1E-61 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 233 6.4E-67 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10935 91b9e2bd0c4bccc87437fa7e7b6433c7 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 Pfam PF07730 Histidine kinase 143 210 1.1E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 SUPERFAMILY SSF55874 217 336 2.88E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 SMART SM00387 246 339 3.5E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 246 336 4.0E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 PIRSF PIRSF037431 1 345 3.6E-124 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 A21D_RS00370 765d310ad5b27cb415686513e8fff3c4 345 Gene3D G3DSA:3.30.565.10 175 338 9.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS05985 40b8d7bc6844e2e884858e9f378e5a6d 332 SUPERFAMILY SSF53807 52 327 2.67E-41 T 28-03-2018 A21D_RS05985 40b8d7bc6844e2e884858e9f378e5a6d 332 Gene3D G3DSA:3.40.50.1980 38 165 3.4E-18 T 28-03-2018 A21D_RS05985 40b8d7bc6844e2e884858e9f378e5a6d 332 Pfam PF01497 Periplasmic binding protein 64 299 1.5E-26 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS05985 40b8d7bc6844e2e884858e9f378e5a6d 332 Gene3D G3DSA:3.40.50.1980 166 329 1.0E-28 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 Pfam PF07690 Major Facilitator Superfamily 22 412 1.2E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 Gene3D G3DSA:1.20.1250.20 262 476 1.1E-28 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 421 1.8E-112 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 4.0E-11 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 4.0E-11 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 4.0E-11 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 4.0E-11 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 Gene3D G3DSA:1.20.1250.20 5 201 3.8E-33 T 28-03-2018 A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 SUPERFAMILY SSF103473 251 464 1.1E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS12725 828b1d25b809a689d8dd35ade1cc2289 476 SUPERFAMILY SSF103473 13 198 1.1E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS08655 7487014e6b1b890bbce3c12d2912278c 231 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 130 2.0E-24 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A21D_RS08655 7487014e6b1b890bbce3c12d2912278c 231 Gene3D G3DSA:3.40.50.10320 1 231 8.9E-48 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A21D_RS08655 7487014e6b1b890bbce3c12d2912278c 231 SUPERFAMILY SSF102588 1 225 2.35E-47 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 Pfam PF01979 Amidohydrolase family 79 361 1.4E-10 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 Pfam PF13382 Adenine deaminase C-terminal domain 432 571 2.9E-33 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 SUPERFAMILY SSF51338 331 367 3.3E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 SUPERFAMILY SSF51338 18 82 3.3E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 SUPERFAMILY SSF51556 82 327 6.38E-12 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 Gene3D G3DSA:2.30.40.10 14 198 4.6E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS10980 06aa57349403868b341e578d8eba17e0 580 Gene3D G3DSA:2.30.40.10 271 371 1.9E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 Pfam PF03099 Biotin/lipoate A/B protein ligase family 49 153 1.7E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 SUPERFAMILY SSF82649 245 331 5.23E-26 T 28-03-2018 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 SUPERFAMILY SSF55681 4 244 1.49E-80 T 28-03-2018 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 325 1.6E-121 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 Gene3D G3DSA:3.30.390.50 250 331 5.8E-26 T 28-03-2018 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 246 330 6.6E-29 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A21D_RS13250 950573874bbfd4e652650bc84125f79a 331 Gene3D G3DSA:3.30.930.10 2 249 9.7E-71 T 28-03-2018 A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 SMART SM00345 19 77 4.9E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 SMART SM00895 87 209 1.3E-6 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 Gene3D G3DSA:1.20.120.530 79 218 2.2E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 6.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 6.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 1.0E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 SUPERFAMILY SSF48008 83 214 3.4E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 Gene3D G3DSA:1.10.10.10 1 78 9.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 Pfam PF07729 FCD domain 93 205 1.3E-18 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS03815 2936e3bbae346d00af4160dc531224c5 218 SUPERFAMILY SSF46785 13 81 3.76E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14995 954652678cae79b4a143897e0444abfc 217 SUPERFAMILY SSF52777 1 209 2.86E-63 T 28-03-2018 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 185 195 - T 28-03-2018 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 Pfam PF00302 Chloramphenicol acetyltransferase 2 204 5.9E-76 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 SMART SM01059 1 204 5.0E-91 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 Gene3D G3DSA:3.30.559.10 1 211 3.6E-29 T 28-03-2018 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 10 203 5.0E-61 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A21D_RS14995 954652678cae79b4a143897e0444abfc 217 PIRSF PIRSF000440 1 213 4.3E-76 T 28-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 SUPERFAMILY SSF53623 5 273 3.55E-83 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 SUPERFAMILY SSF53244 295 419 6.96E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 371 4.4E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 419 1.4E-108 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 Gene3D G3DSA:3.40.1190.10 2 294 1.9E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 PIRSF PIRSF001563 1 424 3.5E-135 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 Pfam PF08245 Mur ligase middle domain 45 268 2.1E-15 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS15165 ee3f33b646100a33c569f4e5f7aa6514 424 Gene3D G3DSA:3.90.190.20 295 424 3.4E-22 T 28-03-2018 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 3 300 40.939 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 Pfam PF01180 Dihydroorotate dehydrogenase 3 285 4.1E-88 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 SUPERFAMILY SSF51395 1 299 9.99E-88 T 28-03-2018 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 PIRSF PIRSF000164 1 301 7.9E-87 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 Gene3D G3DSA:3.20.20.70 1 302 8.3E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 3 299 9.7E-122 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A21D_RS18270 e36e4097229e0c02c00792d007510dc8 302 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 39 58 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A21D_RS15520 1d409fc4e3af8d3054d24d4bf99c0a54 112 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 107 2.9E-28 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Gene3D G3DSA:3.30.870.10 530 717 1.1E-29 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Pfam PF02503 Polyphosphate kinase middle domain 146 351 1.3E-68 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Gene3D G3DSA:3.30.870.10 347 529 2.7E-18 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Pfam PF13090 Polyphosphate kinase C-terminal domain 361 707 8.9E-151 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 SUPERFAMILY SSF143724 130 333 3.73E-56 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 25 708 2.5E-270 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 PIRSF PIRSF015589 7 718 9.3E-277 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 SUPERFAMILY SSF56024 531 711 1.54E-68 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Gene3D G3DSA:3.30.1840.10 132 333 2.2E-67 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Gene3D G3DSA:1.20.58.310 28 131 4.1E-40 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 SUPERFAMILY SSF56024 346 525 1.66E-52 T 28-03-2018 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Hamap MF_00347 Polyphosphate kinase [ppk]. 24 712 29.335 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 SUPERFAMILY SSF140356 22 128 4.71E-40 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A21D_RS13730 926c810a865c1c6949e4cb60451b2ca0 718 Pfam PF13089 Polyphosphate kinase N-terminal domain 26 132 4.6E-41 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 498 5.7E-256 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 3.6E-71 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 SUPERFAMILY SSF47917 372 500 8.89E-48 T 28-03-2018 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 SUPERFAMILY SSF50615 10 94 6.8E-30 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 5.9E-47 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 SUPERFAMILY SSF52540 95 370 1.45E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 6.7E-20 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 PIRSF PIRSF039088 1 501 1.5E-248 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Gene3D G3DSA:1.20.150.20 373 498 4.4E-51 T 28-03-2018 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Gene3D G3DSA:2.40.30.20 3 82 3.1E-37 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Gene3D G3DSA:3.40.50.300 83 364 6.3E-118 T 28-03-2018 A21D_RS04545 303ea82d940be7bbe21718ae5620015f 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.143 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS09285 0b9b52142cd863cffcbe602e8857a729 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 215 1.3E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS09285 0b9b52142cd863cffcbe602e8857a729 222 Gene3D G3DSA:1.10.3720.10 4 221 1.5E-35 T 28-03-2018 A21D_RS09285 0b9b52142cd863cffcbe602e8857a729 222 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 216 1.7E-66 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A21D_RS09285 0b9b52142cd863cffcbe602e8857a729 222 SUPERFAMILY SSF161098 5 216 1.31E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS09270 5579d33c19ad6b53e4f037f57f91b1e4 197 Gene3D G3DSA:3.90.550.10 1 197 2.2E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS09270 5579d33c19ad6b53e4f037f57f91b1e4 197 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 3 191 22.546 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A21D_RS09270 5579d33c19ad6b53e4f037f57f91b1e4 197 Pfam PF12804 MobA-like NTP transferase domain 7 161 1.7E-25 T 28-03-2018 IPR025877 MobA-like NTP transferase A21D_RS09270 5579d33c19ad6b53e4f037f57f91b1e4 197 SUPERFAMILY SSF53448 1 189 2.53E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS11335 be71222a7f19caea8536006f1e2b97da 119 Pfam PF00581 Rhodanese-like domain 30 118 8.6E-15 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11335 be71222a7f19caea8536006f1e2b97da 119 SMART SM00450 29 118 2.7E-16 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11335 be71222a7f19caea8536006f1e2b97da 119 Gene3D G3DSA:3.40.250.10 24 119 4.5E-27 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11335 be71222a7f19caea8536006f1e2b97da 119 SUPERFAMILY SSF52821 8 118 3.4E-31 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 760 1.1E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 SUPERFAMILY SSF64484 5 1182 0.0 T 28-03-2018 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 2.8E-88 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 3.6E-29 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 385 6.5E-9 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 SMART SM00663 224 503 2.0E-184 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1190 18.655 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1180 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Gene3D G3DSA:2.40.40.20 335 477 2.2E-39 T 28-03-2018 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Gene3D G3DSA:2.40.50.100 911 1028 4.6E-41 T 28-03-2018 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1128 1.3E-67 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06410 99960acddc1fa2154f279bb8d9d0138d 1202 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 9.9E-34 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS17615 123087c65d07d416ef1091b41c0c9333 434 SUPERFAMILY SSF63411 12 224 5.87E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17615 123087c65d07d416ef1091b41c0c9333 434 Pfam PF05193 Peptidase M16 inactive domain 184 363 1.2E-24 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A21D_RS17615 123087c65d07d416ef1091b41c0c9333 434 Gene3D G3DSA:3.30.830.10 247 431 2.5E-33 T 28-03-2018 A21D_RS17615 123087c65d07d416ef1091b41c0c9333 434 SUPERFAMILY SSF63411 251 418 2.67E-33 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17615 123087c65d07d416ef1091b41c0c9333 434 Gene3D G3DSA:3.30.830.10 5 232 1.3E-28 T 28-03-2018 A21D_RS16065 4632f6f93357e1040dd4062dfa9c031a 130 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 1.6E-9 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family A21D_RS16065 4632f6f93357e1040dd4062dfa9c031a 130 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 8.1E-17 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family A21D_RS16065 4632f6f93357e1040dd4062dfa9c031a 130 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 2.8E-38 T 28-03-2018 IPR014211 Stage III sporulation protein AD A21D_RS16985 1e58d93bd6c640138660348478974299 264 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 10 259 1.0E-53 T 28-03-2018 IPR005226 UPF0014 family A21D_RS16985 1e58d93bd6c640138660348478974299 264 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 253 1.2E-81 T 28-03-2018 IPR005226 UPF0014 family A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Hamap MF_01252 Flavohemoprotein [hmp]. 8 407 54.513 T 28-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Gene3D G3DSA:1.10.490.10 1 166 6.5E-44 T 28-03-2018 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 SUPERFAMILY SSF52343 271 403 1.15E-34 T 28-03-2018 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Pfam PF00970 Oxidoreductase FAD-binding domain 165 267 2.9E-8 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 SUPERFAMILY SSF46458 9 150 5.32E-40 T 28-03-2018 IPR009050 Globin-like A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Gene3D G3DSA:2.40.30.10 167 268 2.0E-24 T 28-03-2018 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Pfam PF00042 Globin 14 109 1.5E-9 T 28-03-2018 IPR000971 Globin GO:0020037 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 SUPERFAMILY SSF63380 158 269 5.26E-29 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Pfam PF00175 Oxidoreductase NAD-binding domain 279 382 6.3E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A21D_RS06940 3633ef71eb97058b429d8381704a2852 410 Gene3D G3DSA:3.40.50.80 269 407 6.9E-25 T 28-03-2018 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 Gene3D G3DSA:3.40.50.1400 1 156 4.8E-28 T 28-03-2018 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 ProSitePatterns PS00534 Ferrochelatase signature. 177 195 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 SUPERFAMILY SSF53800 3 306 6.05E-89 T 28-03-2018 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 TIGRFAM TIGR00109 hemH: ferrochelatase 2 306 7.2E-101 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 Hamap MF_00323 Ferrochelatase [hemH]. 4 307 32.268 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 Pfam PF00762 Ferrochelatase 5 306 1.3E-85 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A21D_RS13230 744a2b789a5ddef3d4e6a158a53d167a 313 Gene3D G3DSA:3.40.50.1400 157 288 1.2E-42 T 28-03-2018 A21D_RS08605 12356ad669da2a7dfd60066c47eb76ac 294 SUPERFAMILY SSF161098 29 279 2.8E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08605 12356ad669da2a7dfd60066c47eb76ac 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 284 5.8E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08605 12356ad669da2a7dfd60066c47eb76ac 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 21 291 1.4E-78 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A21D_RS08605 12356ad669da2a7dfd60066c47eb76ac 294 Gene3D G3DSA:1.10.3720.10 21 294 2.1E-39 T 28-03-2018 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 SUPERFAMILY SSF51395 13 316 6.72E-59 T 28-03-2018 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 Gene3D G3DSA:1.10.1200.80 250 318 1.8E-13 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 Pfam PF01207 Dihydrouridine synthase (Dus) 15 314 8.6E-49 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 PIRSF PIRSF006621 1 318 2.5E-82 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A21D_RS11090 8f542bb94b5ea89b5405bc723b5f6b41 319 Gene3D G3DSA:3.20.20.70 10 249 3.1E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS00535 64732ca2945a2952e4825722069e98b2 171 SUPERFAMILY SSF53474 4 167 1.23E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS00535 64732ca2945a2952e4825722069e98b2 171 Pfam PF12146 Serine aminopeptidase, S33 60 133 1.2E-7 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A21D_RS00535 64732ca2945a2952e4825722069e98b2 171 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 79 6.0E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS00535 64732ca2945a2952e4825722069e98b2 171 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 6.0E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS00535 64732ca2945a2952e4825722069e98b2 171 Gene3D G3DSA:3.40.50.1820 2 171 1.3E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS11635 17ac6fbe8144875742fdc833615a523b 291 SUPERFAMILY SSF52540 3 218 4.17E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11635 17ac6fbe8144875742fdc833615a523b 291 Gene3D G3DSA:3.40.50.300 1 290 4.3E-43 T 28-03-2018 A21D_RS11635 17ac6fbe8144875742fdc833615a523b 291 SMART SM00382 27 205 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11635 17ac6fbe8144875742fdc833615a523b 291 Pfam PF00005 ABC transporter 18 154 9.2E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 1.2E-23 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 1.2E-23 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 304 325 1.2E-23 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 1.2E-23 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Gene3D G3DSA:3.30.1360.70 3 110 1.1E-34 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 554 27.734 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 SUPERFAMILY SSF47323 430 554 1.7E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 554 7.1E-164 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Pfam PF00750 tRNA synthetases class I (R) 104 398 8.1E-26 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 SMART SM01016 9 95 5.0E-38 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Gene3D G3DSA:3.40.50.620 111 363 1.4E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 SUPERFAMILY SSF52374 119 446 7.51E-96 T 28-03-2018 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Gene3D G3DSA:1.10.730.10 401 554 2.9E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 SUPERFAMILY SSF55190 9 115 1.57E-28 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 95 1.8E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 SMART SM00836 435 554 3.5E-56 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS04750 7360ea90b506ac4e0f96e0a46413f429 554 Pfam PF05746 DALR anticodon binding domain 435 554 4.7E-38 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS09165 48534c512f423794f951689641cdbaf9 262 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 249 1.9E-91 T 28-03-2018 IPR022493 Integral membrane YkoY A21D_RS09165 48534c512f423794f951689641cdbaf9 262 Pfam PF03741 Integral membrane protein TerC family 15 206 5.1E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A21D_RS09165 48534c512f423794f951689641cdbaf9 262 SUPERFAMILY SSF103473 10 247 1.57E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 SUPERFAMILY SSF52794 431 514 1.88E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Pfam PF00874 PRD domain 215 303 7.2E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Pfam PF00874 PRD domain 341 420 4.7E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:1.10.1790.10 306 424 1.4E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 SUPERFAMILY SSF63520 336 424 1.83E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:1.10.10.10 13 81 3.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:1.10.10.10 106 171 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 SUPERFAMILY SSF55804 526 666 2.09E-25 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 529 666 3.1E-23 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:1.10.1790.10 204 305 2.1E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Pfam PF05043 Mga helix-turn-helix domain 111 184 2.6E-11 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Pfam PF08279 HTH domain 19 77 9.7E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:3.40.930.10 524 669 2.3E-24 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 Gene3D G3DSA:3.40.50.2300 430 521 9.2E-18 T 28-03-2018 A21D_RS02340 626fa87f17f8fbecefba5b510761e10f 670 SUPERFAMILY SSF63520 206 305 1.14E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08320 3f0ea5445b8dcfaf6729c705a656acbc 468 Pfam PF04293 SpoVR like protein 3 406 2.7E-161 T 28-03-2018 IPR007390 Sporulation stage V, protein R A21D_RS19225 02f104fb852a70e1f1baa3fc7b0d7f47 342 Gene3D G3DSA:3.80.30.20 79 303 2.6E-9 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A21D_RS19225 02f104fb852a70e1f1baa3fc7b0d7f47 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 2.4E-151 T 28-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 A21D_RS19225 02f104fb852a70e1f1baa3fc7b0d7f47 342 SUPERFAMILY SSF102114 84 230 2.75E-5 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 Gene3D G3DSA:3.30.2130.10 334 408 3.4E-16 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 SUPERFAMILY SSF55021 258 344 5.15E-16 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 SUPERFAMILY SSF55021 333 402 4.34E-18 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 SUPERFAMILY SSF53633 4 247 5.5E-66 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 Gene3D G3DSA:3.40.1160.10 1 239 1.3E-65 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 401 3.4E-132 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 Gene3D G3DSA:3.30.70.260 240 333 7.7E-19 T 28-03-2018 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 Pfam PF13840 ACT domain 333 396 2.7E-22 T 28-03-2018 IPR027795 GATS-like ACT domain A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 PIRSF PIRSF000726 1 67 7.6E-9 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 PIRSF PIRSF000726 59 406 6.4E-94 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 Pfam PF00696 Amino acid kinase family 3 235 7.7E-48 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS17665 8d170f007796e9989fad472d09e4beca 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 66 399 1.5E-92 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 193 226 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 311 344 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 273 306 9.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 393 426 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 152 185 98.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00028 233 266 36.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SUPERFAMILY SSF48452 131 360 2.37E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Gene3D G3DSA:1.10.260.40 7 74 4.4E-11 T 28-03-2018 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Gene3D G3DSA:1.25.40.10 75 192 8.5E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Gene3D G3DSA:1.25.40.10 284 321 0.0016 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Gene3D G3DSA:1.10.150.200 193 283 4.0E-7 T 28-03-2018 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SUPERFAMILY SSF47413 10 66 2.2E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS11015 1737571570f8d166946d467b029bb793 429 SMART SM00530 14 68 3.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Pfam PF01381 Helix-turn-helix 15 67 3.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS11015 1737571570f8d166946d467b029bb793 429 Gene3D G3DSA:1.25.40.10 322 425 0.0019 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 SUPERFAMILY SSF58104 296 564 2.75E-69 T 28-03-2018 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 SUPERFAMILY SSF58104 233 263 2.75E-69 T 28-03-2018 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 SMART SM00304 208 261 6.6E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 388 415 8.7E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 20 45 8.7E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 417 446 8.7E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Pfam PF12729 Four helix bundle sensory module for signal transduction 11 167 5.5E-14 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Pfam PF00672 HAMP domain 208 252 2.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 359 518 1.2E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 SMART SM00283 290 565 7.6E-78 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Gene3D G3DSA:1.10.287.950 144 313 1.9E-8 T 28-03-2018 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Gene3D G3DSA:1.10.287.950 314 508 1.1E-49 T 28-03-2018 A21D_RS01015 af8cb353bebcdaa23bd7df469f634b16 566 Gene3D G3DSA:1.10.287.950 509 558 3.1E-4 T 28-03-2018 A21D_RS17330 fe379533f735f44d32bc854335377cbb 116 Pfam PF01844 HNH endonuclease 36 93 3.4E-5 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A21D_RS17330 fe379533f735f44d32bc854335377cbb 116 Gene3D G3DSA:3.40.1800.10 14 110 5.6E-12 T 28-03-2018 A21D_RS17330 fe379533f735f44d32bc854335377cbb 116 SMART SM00507 23 91 4.3E-7 T 28-03-2018 IPR003615 HNH nuclease A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 152 185 7.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Pfam PF13432 Tetratricopeptide repeat 38 98 0.0039 T 28-03-2018 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 114 151 2.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 2 113 3.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Pfam PF13429 Tetratricopeptide repeat 141 390 4.5E-7 T 28-03-2018 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 201 234 460.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 269 302 44.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 337 370 87.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 134 167 420.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 100 133 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SMART SM00028 235 268 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SUPERFAMILY SSF48452 33 194 4.46E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 186 249 4.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 304 422 4.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 Gene3D G3DSA:1.25.40.10 250 303 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SUPERFAMILY SSF48452 176 305 4.05E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16645 7b589e910849f5edaa50c2f360860733 422 SUPERFAMILY SSF48452 353 402 4.05E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.40.10 1338 1438 4.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.40.10 1253 1337 3.0E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 440 456 1.3E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 265 278 1.3E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 214 233 1.3E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.40.1120 920 1001 1.7E-14 T 28-03-2018 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 PIRSF PIRSF015477 3 1443 0.0 T 28-03-2018 IPR012103 Peptidase S8A, bacillopeptidase F A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:3.30.70.80 58 179 6.3E-8 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.40.1120 846 916 1.7E-8 T 28-03-2018 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.120.260 627 784 2.6E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 269 279 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:3.40.50.200 180 510 5.0E-76 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Pfam PF13715 CarboxypepD_reg-like domain 921 996 3.7E-13 T 28-03-2018 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Gene3D G3DSA:2.60.40.1310 1062 1249 1.3E-9 T 28-03-2018 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 SUPERFAMILY SSF49464 920 1018 1.2E-17 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Pfam PF05922 Peptidase inhibitor I9 68 176 1.9E-6 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 SUPERFAMILY SSF49899 629 782 3.96E-10 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 SUPERFAMILY SSF52743 161 505 4.19E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 SUPERFAMILY SSF49464 852 915 1.2E-8 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Pfam PF00082 Subtilase family 214 495 1.3E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Pfam PF05547 Immune inhibitor A peptidase M6 680 780 6.4E-14 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A21D_RS14040 fd360e06946b6352d992d09c6697cb4a 1443 Pfam PF13620 Carboxypeptidase regulatory-like domain 853 914 3.0E-7 T 28-03-2018 A21D_RS07885 1be8dfc7255ed550aa46650313917052 509 Pfam PF01522 Polysaccharide deacetylase 324 436 6.1E-38 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS07885 1be8dfc7255ed550aa46650313917052 509 Gene3D G3DSA:3.90.640.20 144 263 1.4E-4 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 A21D_RS07885 1be8dfc7255ed550aa46650313917052 509 Gene3D G3DSA:3.20.20.370 264 509 1.6E-61 T 28-03-2018 A21D_RS07885 1be8dfc7255ed550aa46650313917052 509 SUPERFAMILY SSF88713 320 507 3.46E-64 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 SUPERFAMILY SSF141986 188 335 1.83E-24 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 PIRSF PIRSF028757 2 344 7.6E-67 T 28-03-2018 IPR003507 Peptidase family S66 A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 Pfam PF02016 LD-carboxypeptidase 14 328 5.7E-70 T 28-03-2018 IPR003507 Peptidase family S66 A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 Gene3D G3DSA:3.50.30.60 171 341 7.7E-50 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 Gene3D G3DSA:3.40.50.10740 1 170 1.1E-48 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A21D_RS11290 2ef14ce1c97af3af3a8337205b02385d 344 SUPERFAMILY SSF52317 2 165 3.71E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS07030 9b7f79760696959ebc02b95f1d6b37b8 320 Gene3D G3DSA:1.10.3720.10 2 307 5.5E-42 T 28-03-2018 A21D_RS07030 9b7f79760696959ebc02b95f1d6b37b8 320 SUPERFAMILY SSF161098 90 301 3.53E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07030 9b7f79760696959ebc02b95f1d6b37b8 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 1.4E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS16870 010a3a2586ccd5a621662bf342e5b114 69 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 49 2.8E-20 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS16870 010a3a2586ccd5a621662bf342e5b114 69 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 65 17.439 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS16870 010a3a2586ccd5a621662bf342e5b114 69 Pfam PF02416 mttA/Hcf106 family 5 53 8.0E-21 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A21D_RS16870 010a3a2586ccd5a621662bf342e5b114 69 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.8E-7 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS16870 010a3a2586ccd5a621662bf342e5b114 69 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.8E-7 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 Gene3D G3DSA:1.10.10.10 1 135 8.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 Pfam PF01047 MarR family 31 89 2.4E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 SUPERFAMILY SSF46785 7 130 9.93E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 ProSitePatterns PS01117 MarR-type HTH domain signature. 63 97 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 1.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS14920 a247bb070954420c413fd0faf798f0f1 135 SMART SM00347 24 128 1.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 Gene3D G3DSA:1.10.10.60 141 203 6.6E-9 T 28-03-2018 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 PRINTS PR00046 Major sigma-70 factor signature 197 212 3.2E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 PRINTS PR00046 Major sigma-70 factor signature 212 223 3.2E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 PRINTS PR00046 Major sigma-70 factor signature 176 188 3.2E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 PRINTS PR00046 Major sigma-70 factor signature 78 91 3.2E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 Pfam PF04542 Sigma-70 region 2 54 122 8.9E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 PIRSF PIRSF000770 4 241 6.5E-81 T 28-03-2018 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 Gene3D G3DSA:3.30.1190.10 204 229 2.0E-9 T 28-03-2018 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 228 3.5E-113 T 28-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 SUPERFAMILY SSF88946 8 120 1.44E-34 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 222 1.0E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 SUPERFAMILY SSF88659 139 223 1.73E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 Pfam PF04545 Sigma-70, region 4 174 223 5.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15480 b669469cdd8df1c5436e4a4c94c198b2 241 Gene3D G3DSA:1.10.601.10 20 121 4.1E-31 T 28-03-2018 A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 314 554 6.5E-89 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 SUPERFAMILY SSF56091 12 199 4.32E-35 T 28-03-2018 A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 4 299 2.8E-73 T 28-03-2018 IPR014146 DNA ligase D, ligase domain A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 Pfam PF01068 ATP dependent DNA ligase domain 15 199 2.3E-33 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 Gene3D G3DSA:3.30.470.30 2 137 1.1E-26 T 28-03-2018 A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 12 582 4.0E-181 T 28-03-2018 IPR014143 DNA ligase D A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 175 199 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A21D_RS09190 9dfec2d650ce341b5deca1ca2afed987 599 Gene3D G3DSA:3.30.1490.70 138 200 2.8E-11 T 28-03-2018 A21D_RS06205 f323714602c727c561e8b7a45135e37b 130 SUPERFAMILY SSF54211 5 130 1.9E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS06205 f323714602c727c561e8b7a45135e37b 130 Gene3D G3DSA:3.30.230.10 3 130 7.2E-52 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS06205 f323714602c727c561e8b7a45135e37b 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.792 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A21D_RS06205 f323714602c727c561e8b7a45135e37b 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A21D_RS06205 f323714602c727c561e8b7a45135e37b 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 3.5E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 PIRSF PIRSF006779 1 277 2.3E-96 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 5 270 9.9E-73 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 Gene3D G3DSA:2.40.30.90 169 277 1.0E-23 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 Gene3D G3DSA:3.40.50.10790 3 165 7.4E-53 T 28-03-2018 A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 SUPERFAMILY SSF102522 4 162 1.12E-55 T 28-03-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A21D_RS12745 baa6fba2d5465397bf45ab26f9469eae 281 SUPERFAMILY SSF101852 171 275 5.36E-29 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Pfam PF02824 TGS domain 8 64 6.2E-7 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Gene3D G3DSA:3.40.50.800 538 647 1.4E-28 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 4.9E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 4.9E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 4.9E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 4.9E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 4.9E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 SUPERFAMILY SSF81271 8 64 1.35E-11 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 SUPERFAMILY SSF52954 533 641 3.47E-31 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 324 535 6.6E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 641 35.12 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 SUPERFAMILY SSF55681 243 532 4.78E-93 T 28-03-2018 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 SUPERFAMILY SSF55186 67 241 7.06E-65 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Gene3D G3DSA:3.30.930.10 228 537 1.0E-101 T 28-03-2018 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Gene3D G3DSA:3.10.20.30 5 67 3.2E-13 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 SMART SM00863 170 219 1.1E-25 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Gene3D G3DSA:3.30.980.10 72 227 5.0E-47 T 28-03-2018 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 219 6.7E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 638 2.7E-235 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS14655 3a48636182742b5e706921bd7003f61d 648 Pfam PF03129 Anticodon binding domain 547 637 1.4E-22 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS13815 22c1488717232cc0b7a7b3cb9db9a640 88 Gene3D G3DSA:3.40.50.2300 1 88 4.5E-22 T 28-03-2018 A21D_RS13815 22c1488717232cc0b7a7b3cb9db9a640 88 SUPERFAMILY SSF52794 1 86 2.43E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS13815 22c1488717232cc0b7a7b3cb9db9a640 88 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 77 2.7E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 SUPERFAMILY SSF53335 59 242 3.16E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 Gene3D G3DSA:3.40.50.150 63 278 2.5E-58 T 28-03-2018 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 Gene3D G3DSA:3.10.290.10 2 61 2.9E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 Pfam PF01728 FtsJ-like methyltransferase 60 243 9.2E-17 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 Pfam PF01479 S4 domain 5 47 4.7E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 237 1.6E-90 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 PIRSF PIRSF005578 1 265 6.7E-102 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 SUPERFAMILY SSF55174 3 69 7.21E-12 T 28-03-2018 A21D_RS16135 825d46c3d47c0192bbf38804c1e9f7b0 278 SMART SM00363 4 67 1.8E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 Pfam PF00005 ABC transporter 19 158 7.8E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 Gene3D G3DSA:3.40.50.300 1 262 5.4E-56 T 28-03-2018 A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 SMART SM00382 28 206 2.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 SUPERFAMILY SSF52540 3 217 4.47E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03835 cef0d7d6f44b8d2446e4282806ea3e05 293 Pfam PF13732 Domain of unknown function (DUF4162) 211 288 1.3E-8 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 A21D_RS04330 cdc279d23bceb1013776237414cd7530 287 SMART SM00650 32 195 3.0E-55 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A21D_RS04330 cdc279d23bceb1013776237414cd7530 287 Pfam PF00398 Ribosomal RNA adenine dimethylase 17 262 1.0E-49 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A21D_RS04330 cdc279d23bceb1013776237414cd7530 287 SUPERFAMILY SSF53335 24 259 3.92E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS04330 cdc279d23bceb1013776237414cd7530 287 Gene3D G3DSA:3.40.50.150 1 200 1.7E-34 T 28-03-2018 A21D_RS04330 cdc279d23bceb1013776237414cd7530 287 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 48 75 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A21D_RS04925 8b4dad6401c26087b8bea84ae68ba99f 239 SUPERFAMILY SSF52540 4 224 1.01E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04925 8b4dad6401c26087b8bea84ae68ba99f 239 Pfam PF00005 ABC transporter 20 161 3.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04925 8b4dad6401c26087b8bea84ae68ba99f 239 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04925 8b4dad6401c26087b8bea84ae68ba99f 239 SMART SM00382 29 209 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04925 8b4dad6401c26087b8bea84ae68ba99f 239 Gene3D G3DSA:3.40.50.300 1 232 2.6E-66 T 28-03-2018 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.9E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 SUPERFAMILY SSF54686 1 137 4.45E-61 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 Gene3D G3DSA:3.90.1170.10 2 139 1.2E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 42.346 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.9E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.9E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.9E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.9E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06340 46e8d8852060234e81609b236c308fcd 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.7E-65 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS09555 a0f2df1a55b47213040678dbb88fbf80 306 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 19 295 2.1E-80 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A21D_RS09555 a0f2df1a55b47213040678dbb88fbf80 306 Pfam PF01040 UbiA prenyltransferase family 31 282 6.7E-55 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A21D_RS09555 a0f2df1a55b47213040678dbb88fbf80 306 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 74 96 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site A21D_RS09555 a0f2df1a55b47213040678dbb88fbf80 306 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 14 298 17.15 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 Gene3D G3DSA:3.40.640.10 6 283 1.9E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 Gene3D G3DSA:3.90.100.10 358 474 5.9E-18 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 393 449 6.8E-9 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 SUPERFAMILY SSF55904 330 473 1.57E-18 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 298 6.5E-81 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A21D_RS06870 3c982931ea97fcba5f9b319e11d30984 476 SUPERFAMILY SSF53383 7 352 2.29E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 PIRSF PIRSF020623 1 280 1.3E-99 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 1 275 2.7E-93 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 Pfam PF07848 PaaX-like protein 1 66 1.3E-27 T 28-03-2018 IPR012906 PaaX-like, N-terminal A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 SUPERFAMILY SSF46785 9 81 5.19E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 Pfam PF08223 PaaX-like protein C-terminal domain 161 260 2.0E-28 T 28-03-2018 IPR013225 PaaX-like, C-terminal A21D_RS01825 79f463223b8475638241f63e454d5b3f 281 Gene3D G3DSA:1.10.10.10 1 79 7.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Gene3D G3DSA:3.40.50.720 1 205 5.0E-39 T 28-03-2018 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Gene3D G3DSA:3.90.226.10 479 798 3.2E-41 T 28-03-2018 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 305 8.2E-9 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Pfam PF00378 Enoyl-CoA hydratase/isomerase 493 630 1.5E-9 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 SUPERFAMILY SSF52096 486 796 1.7E-40 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Gene3D G3DSA:1.10.1040.10 206 312 5.8E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 205 1.8E-46 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 SUPERFAMILY SSF48179 364 460 3.66E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 SUPERFAMILY SSF51735 3 206 7.0E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 Gene3D G3DSA:1.10.1040.10 369 464 4.8E-13 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS00290 3ef949d2f8dde7639b4e6b7105aac434 799 SUPERFAMILY SSF48179 206 314 1.36E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS15050 5a8c31023f0260d7ff488844d6fe51eb 202 Pfam PF01725 Ham1 family 4 190 3.6E-58 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A21D_RS15050 5a8c31023f0260d7ff488844d6fe51eb 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 193 3.7E-60 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A21D_RS15050 5a8c31023f0260d7ff488844d6fe51eb 202 SUPERFAMILY SSF52972 1 193 2.04E-69 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A21D_RS15050 5a8c31023f0260d7ff488844d6fe51eb 202 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 195 47.598 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 A21D_RS15050 5a8c31023f0260d7ff488844d6fe51eb 202 Gene3D G3DSA:3.90.950.10 1 198 3.1E-79 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:1.10.1780.10 77 194 5.0E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SUPERFAMILY SSF52540 488 800 5.45E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:3.40.50.300 494 715 1.8E-55 T 28-03-2018 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 573 591 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 664 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 543 561 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 606 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 617 635 2.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SUPERFAMILY SSF52540 163 472 3.63E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SMART SM01086 716 806 9.6E-39 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 716 796 1.1E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SUPERFAMILY SSF81923 5 145 8.5E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SMART SM00382 539 683 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 SMART SM00382 202 346 7.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF02151 UvrB/uvrC motif 421 453 1.0E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF07724 AAA domain (Cdc48 subfamily) 538 709 5.5E-57 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:1.10.1780.10 1 76 6.3E-23 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 1.7E-16 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 91 143 1.4E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:1.10.8.60 346 489 9.6E-46 T 28-03-2018 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:1.10.8.60 716 806 3.8E-27 T 28-03-2018 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 319 2.1E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS06510 7bf84b32a760bc7edcc06e1c711364ab 808 Gene3D G3DSA:3.40.50.300 195 344 2.3E-20 T 28-03-2018 A21D_RS19265 a14bc9cce52721500c00d7c36ea3ec2c 128 Pfam PF06339 Ectoine synthase 1 125 1.9E-57 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS19265 a14bc9cce52721500c00d7c36ea3ec2c 128 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 39.036 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS19265 a14bc9cce52721500c00d7c36ea3ec2c 128 Gene3D G3DSA:2.60.120.10 9 127 8.8E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS19265 a14bc9cce52721500c00d7c36ea3ec2c 128 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 5.0E-61 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS19265 a14bc9cce52721500c00d7c36ea3ec2c 128 SUPERFAMILY SSF51182 1 119 1.75E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS19435 f1f794738d13e2201ae7d245a0b1376e 93 SUPERFAMILY SSF52794 1 89 4.24E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS19435 f1f794738d13e2201ae7d245a0b1376e 93 Gene3D G3DSA:3.40.50.2300 1 92 1.8E-18 T 28-03-2018 A21D_RS19435 f1f794738d13e2201ae7d245a0b1376e 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 79 4.0E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Gene3D G3DSA:3.40.1190.10 101 307 5.6E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 SUPERFAMILY SSF51984 10 99 1.28E-17 T 28-03-2018 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 446 8.3E-136 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Gene3D G3DSA:3.40.50.720 2 100 2.8E-17 T 28-03-2018 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Pfam PF01225 Mur ligase family, catalytic domain 27 110 1.3E-5 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Gene3D G3DSA:3.90.190.20 314 447 3.2E-34 T 28-03-2018 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 35.047 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 SUPERFAMILY SSF53623 105 307 3.79E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 377 2.3E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 Pfam PF08245 Mur ligase middle domain 116 290 1.7E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18390 5743808bb10977bb7e6ad4929e71f624 449 SUPERFAMILY SSF53244 309 448 2.84E-41 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 Gene3D G3DSA:1.20.1640.10 131 335 3.2E-29 T 28-03-2018 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 Gene3D G3DSA:1.20.1640.10 465 680 2.2E-21 T 28-03-2018 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 SUPERFAMILY SSF82866 150 326 9.29E-30 T 28-03-2018 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 SUPERFAMILY SSF82866 459 672 3.27E-20 T 28-03-2018 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 Pfam PF03176 MMPL family 447 670 2.1E-20 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A21D_RS10590 06a9ad64c99dbc587a9ecb18c59378bd 684 Pfam PF03176 MMPL family 147 325 5.3E-24 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 SUPERFAMILY SSF53613 1 300 3.12E-67 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 Pfam PF00294 pfkB family carbohydrate kinase 10 280 5.0E-57 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 Gene3D G3DSA:2.20.150.10 9 37 1.1E-14 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 Gene3D G3DSA:3.40.1190.20 38 287 7.4E-42 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.9E-104 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 5.4E-105 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS03750 34a3a5b116e0c69ba0a70a6b93325186 307 PIRSF PIRSF000535 1 302 1.4E-87 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 Gene3D G3DSA:3.10.105.10 295 496 7.1E-63 T 28-03-2018 A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 PIRSF PIRSF002741 1 514 2.9E-122 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 Gene3D G3DSA:3.40.190.10 201 294 9.4E-31 T 28-03-2018 A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 443 6.3E-96 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 Gene3D G3DSA:3.90.76.10 48 200 1.3E-32 T 28-03-2018 A21D_RS10620 25a7a472753b3388565153f5a0c74f01 525 SUPERFAMILY SSF53850 37 523 5.44E-141 T 28-03-2018 A21D_RS13925 732bbaa2890152be9de4d1101ec10ebd 110 Gene3D G3DSA:3.40.30.30 2 101 2.9E-42 T 28-03-2018 A21D_RS13925 732bbaa2890152be9de4d1101ec10ebd 110 Pfam PF07315 Protein of unknown function (DUF1462) 7 99 1.2E-40 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 A21D_RS13925 732bbaa2890152be9de4d1101ec10ebd 110 PIRSF PIRSF010603 1 103 1.6E-42 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 A21D_RS13925 732bbaa2890152be9de4d1101ec10ebd 110 SUPERFAMILY SSF52833 2 102 8.31E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS16615 520c86efdc2229997411fa83ae272954 389 SUPERFAMILY SSF103263 2 387 6.67E-141 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 Gene3D G3DSA:3.60.150.10 1 389 8.7E-135 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 TIGRFAM TIGR00033 aroC: chorismate synthase 2 369 3.4E-121 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 Hamap MF_00300 Chorismate synthase [aroC]. 1 371 33.944 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 Pfam PF01264 Chorismate synthase 2 363 4.2E-117 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS16615 520c86efdc2229997411fa83ae272954 389 PIRSF PIRSF001456 1 385 2.0E-122 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Pfam PF08378 Nuclease-related domain 14 111 1.8E-12 T 28-03-2018 IPR011528 Nuclease-related domain, NERD A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Pfam PF13245 AAA domain 238 400 3.1E-10 T 28-03-2018 A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 SUPERFAMILY SSF52540 231 610 1.21E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Gene3D G3DSA:3.40.50.300 427 633 6.7E-32 T 28-03-2018 A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Pfam PF13361 UvrD-like helicase C-terminal domain 542 607 3.4E-10 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Pfam PF13361 UvrD-like helicase C-terminal domain 420 537 1.0E-7 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A21D_RS07720 a02e4c31af3da91994cc0723cb285bad 637 Gene3D G3DSA:3.40.50.300 227 426 1.0E-19 T 28-03-2018 A21D_RS14065 4ba00f57aceb221df5e068ac1d9fbd10 312 Pfam PF01040 UbiA prenyltransferase family 35 264 7.6E-37 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A21D_RS14065 4ba00f57aceb221df5e068ac1d9fbd10 312 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 18 305 19.429 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A21D_RS14065 4ba00f57aceb221df5e068ac1d9fbd10 312 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 27 301 2.1E-38 T 28-03-2018 A21D_RS14065 4ba00f57aceb221df5e068ac1d9fbd10 312 PIRSF PIRSF005355 11 310 6.2E-88 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 Gene3D G3DSA:3.40.1690.10 223 358 8.2E-55 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 Pfam PF01312 FlhB HrpN YscU SpaS Family 12 352 1.1E-128 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 SUPERFAMILY SSF160544 249 356 2.09E-40 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 213 231 4.4E-41 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 307 328 4.4E-41 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 277 292 4.4E-41 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 233 250 4.4E-41 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 15 37 4.4E-41 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS17855 ef54938c10e6b43f602e510a2fd1f555 359 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 13 358 3.8E-128 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 A21D_RS15855 0c2f91e8d77466e8f9a8b08faa309abb 423 Gene3D G3DSA:1.20.1250.20 13 203 2.6E-22 T 28-03-2018 A21D_RS15855 0c2f91e8d77466e8f9a8b08faa309abb 423 Gene3D G3DSA:1.20.1250.20 226 410 7.3E-6 T 28-03-2018 A21D_RS15855 0c2f91e8d77466e8f9a8b08faa309abb 423 Pfam PF07690 Major Facilitator Superfamily 24 337 1.0E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS15855 0c2f91e8d77466e8f9a8b08faa309abb 423 SUPERFAMILY SSF103473 15 400 6.02E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 PIRSF PIRSF002122 5 156 8.7E-59 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.846 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.6E-67 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 4.2E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 SUPERFAMILY SSF47973 1 149 1.1E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A21D_RS06395 a3f1778cafdd0559e23ae037208b6588 156 Gene3D G3DSA:1.10.455.10 7 156 1.6E-58 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A21D_RS15495 b058325b39548304263839d140b40c87 359 Gene3D G3DSA:3.20.20.70 1 234 3.5E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS15495 b058325b39548304263839d140b40c87 359 SUPERFAMILY SSF51445 1 236 2.81E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS15495 b058325b39548304263839d140b40c87 359 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 353 1.6E-122 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic A21D_RS15495 b058325b39548304263839d140b40c87 359 SUPERFAMILY SSF50891 252 353 7.59E-28 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS15495 b058325b39548304263839d140b40c87 359 Gene3D G3DSA:2.40.100.10 238 353 1.4E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 1.7E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 1.7E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 1.7E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 142 153 1.7E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 161 315 1.4E-60 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 91 104 2.0E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 234 244 2.0E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 131 145 2.0E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 58 72 2.0E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 PRINTS PR00102 Ornithine carbamoyltransferase signature 296 307 2.0E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 SUPERFAMILY SSF53671 11 318 5.11E-112 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 15 317 1.2E-133 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 14 318 82.692 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 15 155 4.4E-54 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 Gene3D G3DSA:3.40.50.1370 155 319 8.4E-63 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS03665 9c2fbd2f0d5d9c23b7db19b2b0da0534 319 Gene3D G3DSA:3.40.50.1370 3 154 1.9E-61 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 223 242 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 1 21 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 2.2E-53 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 Gene3D G3DSA:1.10.3860.10 1 404 1.8E-134 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 SUPERFAMILY SSF118215 3 396 6.67E-121 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS06995 cd692e1c83384b52057d7eaeebdfd15e 414 Pfam PF00375 Sodium:dicarboxylate symporter family 3 396 2.7E-131 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18255 8257982d6f71dd9cfe7049c39651de9c 255 Pfam PF08241 Methyltransferase domain 46 140 2.8E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS18255 8257982d6f71dd9cfe7049c39651de9c 255 Gene3D G3DSA:3.40.50.150 30 255 2.5E-40 T 28-03-2018 A21D_RS18255 8257982d6f71dd9cfe7049c39651de9c 255 SUPERFAMILY SSF53335 33 204 1.4E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS13465 8ebc5d668bc0d17c911acd7695be42bd 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS13465 8ebc5d668bc0d17c911acd7695be42bd 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS13465 8ebc5d668bc0d17c911acd7695be42bd 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS13465 8ebc5d668bc0d17c911acd7695be42bd 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14475 41a8bd23c56dd4e5aaa3b4aa766af407 226 Pfam PF13483 Beta-lactamase superfamily domain 2 192 2.0E-23 T 28-03-2018 A21D_RS14475 41a8bd23c56dd4e5aaa3b4aa766af407 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 226 36.901 T 28-03-2018 IPR022877 Protein of unknown funcion UPF0173 A21D_RS14475 41a8bd23c56dd4e5aaa3b4aa766af407 226 SUPERFAMILY SSF56281 2 206 2.88E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS14475 41a8bd23c56dd4e5aaa3b4aa766af407 226 SMART SM00849 7 192 1.3E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS14475 41a8bd23c56dd4e5aaa3b4aa766af407 226 Gene3D G3DSA:3.60.15.10 1 222 5.5E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 Pfam PF03069 Acetamidase/Formamidase family 6 384 4.8E-174 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 Gene3D G3DSA:2.60.120.580 150 281 6.9E-34 T 28-03-2018 A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 Gene3D G3DSA:2.60.120.580 6 149 9.2E-30 T 28-03-2018 A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 Gene3D G3DSA:3.10.28.20 296 384 8.2E-18 T 28-03-2018 A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 SUPERFAMILY SSF141130 213 383 1.26E-77 T 28-03-2018 A21D_RS19010 397f8e052210f6e476924efd5a4da3a4 390 SUPERFAMILY SSF141130 21 164 1.26E-77 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 Gene3D G3DSA:3.40.50.1000 463 593 1.9E-34 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 Gene3D G3DSA:2.70.150.10 6 241 1.8E-32 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 548 1.5E-35 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF56784 340 359 6.31E-52 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF56784 431 633 6.31E-52 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF81653 144 240 1.44E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 Gene3D G3DSA:3.40.1110.10 352 462 3.0E-21 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 90 636 2.1E-168 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 113 613 2.1E-86 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 Pfam PF00122 E1-E2 ATPase 139 321 1.8E-43 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF81665 90 143 1.16E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF81665 583 611 1.16E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 SUPERFAMILY SSF81665 241 335 1.16E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 343 349 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 190 204 3.7E-27 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 3.7E-27 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 3.7E-27 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 3.7E-27 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 341 355 3.7E-27 T 28-03-2018 A21D_RS10870 ea2d5aa7ae9a1b54880b6288c2699d66 647 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 3.7E-27 T 28-03-2018 A21D_RS04510 bb800b82b5e35979bef8a74a8ff934ca 274 PIRSF PIRSF015853 1 271 2.9E-105 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A21D_RS04510 bb800b82b5e35979bef8a74a8ff934ca 274 Gene3D G3DSA:3.30.1360.130 211 269 3.7E-23 T 28-03-2018 A21D_RS04510 bb800b82b5e35979bef8a74a8ff934ca 274 Pfam PF04951 D-aminopeptidase 1 262 2.0E-91 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A21D_RS04510 bb800b82b5e35979bef8a74a8ff934ca 274 SUPERFAMILY SSF63992 1 273 3.01E-99 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A21D_RS04510 bb800b82b5e35979bef8a74a8ff934ca 274 Gene3D G3DSA:3.40.50.10780 1 210 3.0E-80 T 28-03-2018 IPR027476 D-aminopeptidase, N-terminal A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Gene3D G3DSA:3.50.50.60 119 253 1.7E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PIRSF PIRSF000350 4 458 1.1E-101 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Gene3D G3DSA:3.50.50.60 271 339 1.6E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.0E-40 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.0E-40 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.0E-40 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.0E-40 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.0E-40 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 8.3E-37 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Gene3D G3DSA:3.40.50.720 8 41 0.49 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 329 2.1E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 1.1E-175 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 SUPERFAMILY SSF55424 344 467 2.06E-42 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 4.0E-77 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 SUPERFAMILY SSF51905 7 338 9.72E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Gene3D G3DSA:1.10.287.990 42 109 3.2E-24 T 28-03-2018 A21D_RS18650 f376fd223d5cb27be2942eff01f83e26 468 Gene3D G3DSA:3.30.390.30 340 462 8.4E-42 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 Pfam PF00108 Thiolase, N-terminal domain 4 268 2.6E-77 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 SUPERFAMILY SSF53901 3 275 8.38E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 SUPERFAMILY SSF53901 276 396 2.88E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 PIRSF PIRSF000429 1 398 3.1E-135 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 Pfam PF02803 Thiolase, C-terminal domain 276 397 1.0E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 Gene3D G3DSA:3.40.47.10 271 395 9.5E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 Gene3D G3DSA:3.40.47.10 1 270 2.1E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS01835 6cbfe81411edfa97b48a71e50ce644f7 398 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 396 2.1E-142 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS09695 0044565ba187e1a72492131aed5b95f0 395 SUPERFAMILY SSF51905 1 216 8.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09695 0044565ba187e1a72492131aed5b95f0 395 SUPERFAMILY SSF51905 351 391 8.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09695 0044565ba187e1a72492131aed5b95f0 395 Gene3D G3DSA:3.50.50.60 1 208 1.9E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09695 0044565ba187e1a72492131aed5b95f0 395 Gene3D G3DSA:3.30.9.10 209 350 1.7E-16 T 28-03-2018 A21D_RS09695 0044565ba187e1a72492131aed5b95f0 395 Pfam PF01266 FAD dependent oxidoreductase 3 391 6.5E-65 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 PIRSF PIRSF005965 1 124 1.6E-45 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 Pfam PF07736 Chorismate mutase type I 3 118 2.0E-43 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 118 4.0E-33 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 2.5E-43 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 Gene3D G3DSA:3.30.1330.40 2 119 5.8E-46 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A21D_RS16625 ea95c66530c7809dbb97f0ef2d8e90c3 126 SUPERFAMILY SSF55298 2 121 2.98E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A21D_RS08180 3ea08b99949a99726b003d7a03b44e65 163 Gene3D G3DSA:3.40.35.10 4 161 1.2E-49 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS08180 3ea08b99949a99726b003d7a03b44e65 163 SUPERFAMILY SSF52728 3 161 7.32E-43 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS08180 3ea08b99949a99726b003d7a03b44e65 163 Pfam PF03830 PTS system sorbose subfamily IIB component 5 152 1.4E-43 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS06790 ea877b38f2fda3724643f1a32a283042 286 PIRSF PIRSF011575 2 286 4.4E-106 T 28-03-2018 IPR008764 Peptidase U57, YabG A21D_RS06790 ea877b38f2fda3724643f1a32a283042 286 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 6 276 1.0E-116 T 28-03-2018 IPR008764 Peptidase U57, YabG A21D_RS06790 ea877b38f2fda3724643f1a32a283042 286 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 6 282 9.5E-126 T 28-03-2018 IPR008764 Peptidase U57, YabG A21D_RS06790 ea877b38f2fda3724643f1a32a283042 286 Pfam PF05582 YabG peptidase U57 5 281 3.0E-108 T 28-03-2018 IPR008764 Peptidase U57, YabG A21D_RS15185 232503f0d74c1d785169db768064a704 294 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 288 4.4E-61 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A21D_RS15185 232503f0d74c1d785169db768064a704 294 PIRSF PIRSF038471 1 292 7.3E-68 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A21D_RS15185 232503f0d74c1d785169db768064a704 294 Pfam PF04085 rod shape-determining protein MreC 124 277 1.5E-44 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A21D_RS05560 dd092379f44865cd6c370197f90ebfb5 238 Pfam PF03591 AzlC protein 24 163 5.6E-35 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease A21D_RS04265 af7a495441e3d166388619de3e36b287 298 SMART SM00382 52 223 1.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04265 af7a495441e3d166388619de3e36b287 298 Gene3D G3DSA:3.40.50.300 1 282 7.2E-49 T 28-03-2018 A21D_RS04265 af7a495441e3d166388619de3e36b287 298 Pfam PF00005 ABC transporter 44 174 9.1E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04265 af7a495441e3d166388619de3e36b287 298 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04265 af7a495441e3d166388619de3e36b287 298 SUPERFAMILY SSF52540 16 239 2.48E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11655 ebf0fcd17b8e739b5f3d5168b570460e 67 Pfam PF13396 Phospholipase_D-nuclease N-terminal 22 64 1.9E-13 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 Pfam PF07690 Major Facilitator Superfamily 238 399 3.1E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 Pfam PF07690 Major Facilitator Superfamily 34 203 6.2E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 Gene3D G3DSA:1.20.1250.20 214 410 1.0E-29 T 28-03-2018 A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 SUPERFAMILY SSF103473 13 406 6.02E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 Gene3D G3DSA:1.20.1250.20 11 208 4.4E-26 T 28-03-2018 A21D_RS02015 c509629818767f4afbddde3b3e8c9591 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 283 299 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.5E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 Pfam PF00106 short chain dehydrogenase 7 205 7.6E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 200 0.01 T 28-03-2018 A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 SUPERFAMILY SSF51735 4 250 2.08E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS12160 29f197fdf3c966195ab133c19d1ed8ae 255 Gene3D G3DSA:3.40.50.720 1 254 2.7E-52 T 28-03-2018 A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 SMART SM00487 22 222 1.8E-48 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 Pfam PF00271 Helicase conserved C-terminal domain 237 339 1.4E-24 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 Pfam PF00270 DEAD/DEAH box helicase 27 192 2.6E-43 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 Gene3D G3DSA:3.40.50.300 9 222 1.8E-50 T 28-03-2018 A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 Gene3D G3DSA:3.40.50.300 223 436 7.7E-38 T 28-03-2018 A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 SUPERFAMILY SSF52540 33 351 2.64E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15785 0367c3ca8817b9c31e1b4ed011925a10 436 SMART SM00490 258 339 7.1E-28 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 480 46.831 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Gene3D G3DSA:2.30.38.10 305 382 9.9E-20 T 28-03-2018 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Gene3D G3DSA:3.40.50.980 157 304 5.1E-36 T 28-03-2018 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 SUPERFAMILY SSF56801 4 480 6.02E-125 T 28-03-2018 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 471 8.4E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Pfam PF00501 AMP-binding enzyme 10 389 3.0E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Gene3D G3DSA:3.30.300.30 384 482 5.3E-23 T 28-03-2018 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 Gene3D G3DSA:3.40.50.980 1 156 2.2E-35 T 28-03-2018 A21D_RS14090 cbca0776d3b2474c50bf03c87401bb3e 482 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 31 476 2.1E-148 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A21D_RS14975 9406c201b47e03d385ab2133754b6995 170 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 162 7.0E-31 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A21D_RS14975 9406c201b47e03d385ab2133754b6995 170 SUPERFAMILY SSF52540 1 139 5.5E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14975 9406c201b47e03d385ab2133754b6995 170 Gene3D G3DSA:3.40.50.300 1 162 2.6E-18 T 28-03-2018 A21D_RS14975 9406c201b47e03d385ab2133754b6995 170 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 135 8.8E-27 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 Pfam PF00375 Sodium:dicarboxylate symporter family 30 441 8.0E-99 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 232 251 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 6.1E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 Gene3D G3DSA:1.10.3860.10 8 449 3.1E-88 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09180 bc1729478f83d7aa27b66e6ab9fac839 463 SUPERFAMILY SSF118215 29 441 6.8E-92 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 Gene3D G3DSA:3.40.50.2300 6 152 4.7E-32 T 28-03-2018 A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 SMART SM00448 7 120 3.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 Gene3D G3DSA:1.10.10.10 162 236 8.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 Pfam PF00072 Response regulator receiver domain 9 121 7.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 SUPERFAMILY SSF46785 165 218 7.66E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 PIRSF PIRSF006171 5 232 7.7E-80 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 SUPERFAMILY SSF52172 7 136 7.12E-34 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS09700 922f410977cfb9ad1c5487f72082b678 237 Pfam PF08279 HTH domain 167 213 8.4E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 SUPERFAMILY SSF52317 536 677 2.46E-16 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 357 365 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 ProSitePatterns PS00438 Catalase proximal active site signature. 63 79 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 143 161 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 124 141 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 103 121 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 312 339 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 344 370 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PRINTS PR00067 Catalase signature 40 63 9.3E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 Pfam PF06628 Catalase-related immune-responsive 442 505 5.5E-21 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 Pfam PF00199 Catalase 27 411 1.3E-180 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 SUPERFAMILY SSF56634 8 512 8.64E-222 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 PIRSF PIRSF038927 1 681 0.0 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 SMART SM01060 27 415 7.1E-274 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 Gene3D G3DSA:2.40.180.10 1 382 1.2E-166 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS08790 e15b2f818a0e42ffaca28cafb4fa34d4 681 Gene3D G3DSA:3.40.50.880 534 681 2.0E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF04565 RNA polymerase Rpb2, domain 3 472 540 5.9E-31 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF10385 RNA polymerase beta subunit external 1 domain 550 617 2.4E-26 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 205 899 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF04561 RNA polymerase Rpb2, domain 2 372 413 1.1E-5 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 289 3.1E-29 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1150 12.607 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:2.40.270.10 755 851 8.8E-12 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF00562 RNA polymerase Rpb2, domain 6 679 1072 7.0E-165 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF04560 RNA polymerase Rpb2, domain 7 1074 1148 6.3E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 SUPERFAMILY SSF64484 13 290 0.0 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 SUPERFAMILY SSF64484 370 1162 0.0 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:2.40.50.100 676 754 4.6E-26 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:2.40.270.10 852 1058 1.2E-76 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:3.90.1100.10 367 609 1.2E-84 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:3.90.1100.10 20 240 1.6E-57 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:3.90.1100.10 610 674 2.1E-12 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Gene3D G3DSA:3.90.1800.10 1075 1121 8.0E-12 T 28-03-2018 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 ProSitePatterns PS01166 RNA polymerases beta chain signature. 925 937 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06415 aed238342cedbf84d88a97d8a9b4d1d3 1178 Pfam PF04563 RNA polymerase beta subunit 28 457 2.5E-30 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 SUPERFAMILY SSF53178 1 185 1.23E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 Pfam PF01195 Peptidyl-tRNA hydrolase 4 185 9.6E-62 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 185 2.2E-68 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 37.007 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 Gene3D G3DSA:3.40.50.1470 1 186 9.4E-75 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A21D_RS06745 521a7397fbc127226220f89d1a6defe9 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 SMART SM01329 21 418 7.3E-188 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 SUPERFAMILY SSF53659 3 422 4.03E-143 T 28-03-2018 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 4.1E-124 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 Gene3D G3DSA:3.40.718.10 10 423 8.0E-141 T 28-03-2018 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A21D_RS14580 2628f810401a728ef3a17b8c9c0af077 423 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 423 1.3E-220 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 109 117 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 83 96 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 120 133 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 341 352 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 210 223 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 196 209 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 397 410 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 134 149 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 PRINTS PR00415 Aconitase family signature 287 301 6.3E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 Gene3D G3DSA:3.30.499.10 308 470 9.0E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 ProSitePatterns PS01244 Aconitase family signature 2. 397 410 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 Gene3D G3DSA:3.40.1060.10 156 289 5.7E-42 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 ProSitePatterns PS00450 Aconitase family signature 1. 337 353 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 Gene3D G3DSA:3.30.499.10 1 155 8.7E-43 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 462 6.8E-225 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 Pfam PF00330 Aconitase family (aconitate hydratase) 9 455 8.2E-153 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 464 56.725 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A21D_RS01425 aac91c6865882cf8d021a2624fb483b0 470 SUPERFAMILY SSF53732 3 464 8.24E-160 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01060 032314c435bb8ff41ed58181931f87f4 361 Gene3D G3DSA:2.40.100.10 244 358 7.7E-41 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS01060 032314c435bb8ff41ed58181931f87f4 361 SUPERFAMILY SSF50891 246 359 3.72E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS01060 032314c435bb8ff41ed58181931f87f4 361 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 358 6.6E-147 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic A21D_RS01060 032314c435bb8ff41ed58181931f87f4 361 Gene3D G3DSA:3.20.20.70 3 238 3.0E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS01060 032314c435bb8ff41ed58181931f87f4 361 SUPERFAMILY SSF51445 1 241 3.31E-98 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 Pfam PF01634 ATP phosphoribosyltransferase 55 204 3.5E-49 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 SUPERFAMILY SSF53850 3 205 3.91E-62 T 28-03-2018 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 1.8E-60 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 208 52.281 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 Gene3D G3DSA:3.40.190.10 115 208 1.3E-20 T 28-03-2018 A21D_RS03025 d76914c4bdc7efa9a79146b934d00771 208 Gene3D G3DSA:3.40.190.10 3 114 9.3E-35 T 28-03-2018 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF46915 238 318 1.31E-15 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 5.5E-19 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF01138 3' exoribonuclease family, domain 1 321 454 1.2E-16 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF54791 553 638 2.65E-23 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Gene3D G3DSA:3.30.1370.10 548 612 5.4E-14 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF50249 618 699 3.88E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 PIRSF PIRSF005499 2 704 2.4E-298 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 318 7.6E-15 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 690 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Gene3D G3DSA:1.10.10.400 253 309 2.2E-20 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SMART SM00316 618 688 1.3E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SMART SM00322 550 615 1.6E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Gene3D G3DSA:2.40.50.140 613 696 3.4E-24 T 28-03-2018 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF00013 KH domain 554 611 3.1E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF55666 448 547 1.04E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF55666 138 231 8.12E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Gene3D G3DSA:3.30.230.70 310 547 4.3E-59 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF54211 291 485 1.47E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 SUPERFAMILY SSF54211 6 144 2.68E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Gene3D G3DSA:3.30.230.70 13 252 1.2E-56 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF03725 3' exoribonuclease family, domain 2 148 210 1.7E-14 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF03725 3' exoribonuclease family, domain 2 457 527 9.2E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Pfam PF00575 S1 RNA binding domain 617 688 2.2E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS17700 b6106e2f07977725e998ba5d35e796b6 704 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 691 30.636 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 Pfam PF00551 Formyl transferase 2 178 7.3E-41 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 Pfam PF02911 Formyl transferase, C-terminal domain 202 301 7.4E-27 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 Gene3D G3DSA:3.40.50.170 1 204 9.7E-67 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 131 154 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 304 35.086 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 301 1.0E-101 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 SUPERFAMILY SSF53328 3 204 4.45E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 SUPERFAMILY SSF50486 203 303 4.24E-29 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A21D_RS18195 2f12c952f119de1874b4a01619b9f3fa 313 Gene3D G3DSA:3.10.25.10 205 313 1.6E-29 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 Gene3D G3DSA:3.40.50.2000 1 186 3.2E-15 T 28-03-2018 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 Gene3D G3DSA:3.40.50.2000 187 355 3.0E-40 T 28-03-2018 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 SUPERFAMILY SSF53756 7 371 7.07E-84 T 28-03-2018 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 372 5.1E-170 T 28-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 Pfam PF13439 Glycosyltransferase Family 4 12 177 1.0E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A21D_RS16715 1d4a3b929d879e2b9a5e96b4f10d8105 375 Pfam PF00534 Glycosyl transferases group 1 186 350 1.8E-37 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 SMART SM00642 138 496 6.8E-120 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 PIRSF PIRSF001024 106 591 9.6E-52 T 28-03-2018 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Gene3D G3DSA:2.60.40.10 1 124 1.7E-43 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Pfam PF00128 Alpha amylase, catalytic domain 172 468 3.8E-84 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Gene3D G3DSA:2.60.40.1180 531 591 2.0E-4 T 28-03-2018 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Gene3D G3DSA:3.20.20.80 126 485 2.8E-113 T 28-03-2018 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Gene3D G3DSA:3.20.20.80 486 530 2.4E-7 T 28-03-2018 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 SUPERFAMILY SSF51011 507 588 3.8E-5 T 28-03-2018 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 2 120 9.2E-44 T 28-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 A21D_RS01115 751637aaa99d52006369c4c884c3adf9 593 SUPERFAMILY SSF51445 66 502 7.86E-127 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS04905 b3f151da3634e0d8fa987143dca19fc3 134 Gene3D G3DSA:3.10.129.10 2 133 1.3E-26 T 28-03-2018 A21D_RS04905 b3f151da3634e0d8fa987143dca19fc3 134 SUPERFAMILY SSF54637 4 131 3.92E-28 T 28-03-2018 IPR029069 HotDog domain A21D_RS04905 b3f151da3634e0d8fa987143dca19fc3 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 11 126 3.5E-19 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A21D_RS04905 b3f151da3634e0d8fa987143dca19fc3 134 Pfam PF03061 Thioesterase superfamily 41 108 4.2E-10 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 Pfam PF13581 Histidine kinase-like ATPase domain 15 136 2.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 Gene3D G3DSA:3.30.565.10 1 145 1.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 2 137 2.4E-63 T 28-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 34.218 T 28-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 SUPERFAMILY SSF55874 29 135 4.58E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS16345 4dde7780fd964a1c1cf17f65e61cd60b 147 SMART SM00387 35 140 1.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS06620 85cdeb8fda116f630e0ea6f82f71ce9c 73 Pfam PF01381 Helix-turn-helix 10 64 1.1E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS06620 85cdeb8fda116f630e0ea6f82f71ce9c 73 SUPERFAMILY SSF47413 3 70 7.24E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS06620 85cdeb8fda116f630e0ea6f82f71ce9c 73 Gene3D G3DSA:1.10.260.40 1 73 5.1E-16 T 28-03-2018 A21D_RS06620 85cdeb8fda116f630e0ea6f82f71ce9c 73 SMART SM00530 9 64 5.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS16550 37409e49cbd734e984a574627272f389 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 432 2.8E-177 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Gene3D G3DSA:1.20.120.430 1 70 7.2E-19 T 28-03-2018 A21D_RS16550 37409e49cbd734e984a574627272f389 436 PIRSF PIRSF006485 2 436 3.3E-173 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 SUPERFAMILY SSF52540 138 435 6.53E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16550 37409e49cbd734e984a574627272f389 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 138 1.2E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 179 339 1.1E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Gene3D G3DSA:3.40.50.300 229 354 1.7E-18 T 28-03-2018 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.4E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Pfam PF01926 50S ribosome-binding GTPase 179 295 2.4E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.62 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 4.3E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 4.3E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Gene3D G3DSA:3.30.300.20 355 434 7.9E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS16550 37409e49cbd734e984a574627272f389 436 SUPERFAMILY SSF52540 5 167 1.67E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16550 37409e49cbd734e984a574627272f389 436 Gene3D G3DSA:1.20.120.430 71 228 6.6E-44 T 28-03-2018 A21D_RS16550 37409e49cbd734e984a574627272f389 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 5.1E-32 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 Pfam PF00005 ABC transporter 26 182 3.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 SMART SM00382 34 232 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 SUPERFAMILY SSF52540 5 254 1.89E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 Gene3D G3DSA:3.40.50.300 2 333 5.5E-80 T 28-03-2018 A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.6E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS07040 2fd3d6f9feeb0ec3d664cbc41ac712e5 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 291 1.1E-13 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS18260 0619258005ff61e650568157d26053d4 205 SUPERFAMILY SSF53271 5 200 1.57E-52 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS18260 0619258005ff61e650568157d26053d4 205 Pfam PF00156 Phosphoribosyl transferase domain 47 159 1.7E-17 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS18260 0619258005ff61e650568157d26053d4 205 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 205 27.967 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18260 0619258005ff61e650568157d26053d4 205 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 174 8.5E-46 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18260 0619258005ff61e650568157d26053d4 205 Gene3D G3DSA:3.40.50.2020 2 205 1.9E-43 T 28-03-2018 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 Gene3D G3DSA:3.40.1410.10 71 237 1.4E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 Gene3D G3DSA:1.10.10.10 1 70 1.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 SUPERFAMILY SSF46785 2 80 4.63E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 Pfam PF07702 UTRA domain 93 228 8.6E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 SUPERFAMILY SSF64288 59 236 3.93E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 SMART SM00866 92 229 3.4E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 1.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS12120 331d3be1af5b85ab354cd4d2a7a174fd 239 SMART SM00345 14 71 2.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS01025 b1dcb49fdb6c6e9da44578061cf83dc9 485 SUPERFAMILY SSF53720 8 476 8.77E-145 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS01025 b1dcb49fdb6c6e9da44578061cf83dc9 485 Gene3D G3DSA:3.40.605.10 2 269 1.0E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01025 b1dcb49fdb6c6e9da44578061cf83dc9 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS01025 b1dcb49fdb6c6e9da44578061cf83dc9 485 Pfam PF00171 Aldehyde dehydrogenase family 15 473 1.3E-154 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01025 b1dcb49fdb6c6e9da44578061cf83dc9 485 Gene3D G3DSA:3.40.309.10 270 458 1.5E-66 T 28-03-2018 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 SUPERFAMILY SSF46689 346 394 1.12E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 Gene3D G3DSA:1.10.10.60 290 342 1.1E-14 T 28-03-2018 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 Pfam PF12833 Helix-turn-helix domain 316 394 9.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 SUPERFAMILY SSF51621 3 196 1.44E-68 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 Gene3D G3DSA:1.10.10.60 343 395 1.3E-12 T 28-03-2018 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 Gene3D G3DSA:3.20.20.70 3 251 1.1E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 SMART SM00342 310 393 9.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 8 272 3.3E-107 T 28-03-2018 IPR009215 TIM-barrel domain, IGPS-like A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 347 389 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS19245 2b8486b396afdff70fb6c35b7740effc 395 SUPERFAMILY SSF46689 294 344 5.91E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS02720 3596af9c1c8d5263bedbd6c1bee54335 337 Gene3D G3DSA:3.40.1190.20 5 337 1.9E-38 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS02720 3596af9c1c8d5263bedbd6c1bee54335 337 SUPERFAMILY SSF53613 8 324 3.12E-57 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS02720 3596af9c1c8d5263bedbd6c1bee54335 337 Pfam PF00294 pfkB family carbohydrate kinase 8 316 1.3E-27 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Gene3D G3DSA:3.40.50.300 875 1036 7.3E-43 T 28-03-2018 A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Gene3D G3DSA:3.40.50.10810 572 854 1.4E-46 T 28-03-2018 A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 SMART SM00490 916 998 6.5E-29 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Pfam PF04434 SWIM zinc finger 68 90 4.5E-5 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 SUPERFAMILY SSF52540 806 1053 3.65E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 SUPERFAMILY SSF52540 567 804 5.54E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Pfam PF00271 Helicase conserved C-terminal domain 887 998 3.3E-23 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 SMART SM00487 603 788 7.0E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Pfam PF00176 SNF2 family N-terminal domain 623 876 4.6E-53 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A21D_RS08955 e803ff19eedd115f3b79d1bb9e21eded 1054 Pfam PF08455 Bacterial SNF2 helicase associated 229 600 1.1E-87 T 28-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial A21D_RS09390 31006664529d6cdd12dd8148e39ce5bf 384 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 376 1.4E-129 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS09390 31006664529d6cdd12dd8148e39ce5bf 384 Gene3D G3DSA:1.20.1090.10 185 384 6.6E-70 T 28-03-2018 A21D_RS09390 31006664529d6cdd12dd8148e39ce5bf 384 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS09390 31006664529d6cdd12dd8148e39ce5bf 384 Gene3D G3DSA:3.40.50.1970 10 184 4.1E-50 T 28-03-2018 A21D_RS09390 31006664529d6cdd12dd8148e39ce5bf 384 SUPERFAMILY SSF56796 6 383 5.5E-135 T 28-03-2018 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 Pfam PF00072 Response regulator receiver domain 4 112 4.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 SUPERFAMILY SSF52172 1 125 3.13E-35 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 Gene3D G3DSA:3.40.50.2300 1 124 3.1E-31 T 28-03-2018 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 SMART SM00448 2 112 7.7E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.0E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 SMART SM00862 150 225 5.0E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 Gene3D G3DSA:1.10.10.10 125 231 3.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06100 a8a7f878fa52619323534ccda8997549 233 SUPERFAMILY SSF46894 127 226 9.92E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 Gene3D G3DSA:3.60.15.10 498 746 3.6E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 SUPERFAMILY SSF56281 501 749 4.46E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 SMART SM00849 509 710 1.0E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 Pfam PF03772 Competence protein 210 469 1.1E-59 T 28-03-2018 IPR004477 ComEC/Rec2-related protein A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 232 401 3.5E-37 T 28-03-2018 IPR004477 ComEC/Rec2-related protein A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 Pfam PF13567 Domain of unknown function (DUF4131) 26 170 5.3E-15 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 Pfam PF00753 Metallo-beta-lactamase superfamily 508 707 3.9E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15585 ce6c827a0654c64af87603f86f5ba516 756 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 102 739 5.8E-116 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 A21D_RS12175 0d01afc59e54219ee3d95287325f7410 386 SUPERFAMILY SSF89796 2 368 3.14E-121 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS12175 0d01afc59e54219ee3d95287325f7410 386 Gene3D G3DSA:3.40.50.10540 1 384 7.1E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS12175 0d01afc59e54219ee3d95287325f7410 386 Pfam PF02515 CoA-transferase family III 3 367 4.7E-117 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Gene3D G3DSA:3.30.559.10 195 443 1.6E-75 T 28-03-2018 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 SUPERFAMILY SSF52777 201 440 7.56E-73 T 28-03-2018 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 SUPERFAMILY SSF51230 1 92 2.62E-26 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Pfam PF00364 Biotin-requiring enzyme 6 76 2.3E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 210 440 8.3E-73 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Gene3D G3DSA:3.90.1170.30 64 98 0.17 T 28-03-2018 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 SUPERFAMILY SSF47005 140 180 1.57E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Pfam PF02817 e3 binding domain 142 175 2.1E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Gene3D G3DSA:2.40.50.100 5 63 1.1E-16 T 28-03-2018 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A21D_RS05930 a13d7d7ef5d9192d8fa8474b91c831b3 443 Gene3D G3DSA:4.10.320.10 130 194 5.3E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 Gene3D G3DSA:3.40.640.10 38 270 3.6E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 349 3.4E-89 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 SUPERFAMILY SSF53383 7 349 3.44E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 206 215 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 Gene3D G3DSA:3.90.1150.10 271 351 4.5E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 3 350 52.544 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A21D_RS03060 8ab0a7af9ed4c47c02821ed4d4a269ac 353 Pfam PF00155 Aminotransferase class I and II 25 343 9.3E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS02630 dc6f6857c859479809cc822bf31c17a5 377 Pfam PF13439 Glycosyltransferase Family 4 15 179 1.1E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A21D_RS02630 dc6f6857c859479809cc822bf31c17a5 377 Gene3D G3DSA:3.40.50.2000 201 365 1.3E-36 T 28-03-2018 A21D_RS02630 dc6f6857c859479809cc822bf31c17a5 377 SUPERFAMILY SSF53756 5 373 5.89E-70 T 28-03-2018 A21D_RS02630 dc6f6857c859479809cc822bf31c17a5 377 Pfam PF00534 Glycosyl transferases group 1 192 352 6.7E-41 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS02630 dc6f6857c859479809cc822bf31c17a5 377 Gene3D G3DSA:3.40.50.2000 1 200 3.9E-15 T 28-03-2018 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Pfam PF00005 ABC transporter 333 467 1.1E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Pfam PF00005 ABC transporter 18 185 5.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Pfam PF12848 ABC transporter 224 292 1.3E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 SMART SM00382 26 229 3.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 SMART SM00382 341 513 1.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 SUPERFAMILY SSF52540 2 239 2.66E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Pfam PF16326 ABC transporter C-terminal domain 554 619 1.2E-14 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Gene3D G3DSA:3.40.50.300 312 618 1.8E-51 T 28-03-2018 A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 SUPERFAMILY SSF52540 310 519 4.67E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11415 c348243d1586be1872db9a413ef5a7db 624 Gene3D G3DSA:3.40.50.300 1 310 8.0E-59 T 28-03-2018 A21D_RS15680 96eb56db027dc6baf82df3593c506761 444 Gene3D G3DSA:3.90.226.10 20 237 7.4E-22 T 28-03-2018 A21D_RS15680 96eb56db027dc6baf82df3593c506761 444 Pfam PF01972 Serine dehydrogenase proteinase 71 129 3.4E-7 T 28-03-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A21D_RS15680 96eb56db027dc6baf82df3593c506761 444 SUPERFAMILY SSF52096 34 177 3.17E-22 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS15680 96eb56db027dc6baf82df3593c506761 444 Pfam PF01957 NfeD-like C-terminal, partner-binding 292 440 1.0E-13 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain A21D_RS15680 96eb56db027dc6baf82df3593c506761 444 Gene3D G3DSA:2.40.50.140 371 444 1.2E-8 T 28-03-2018 A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 Gene3D G3DSA:1.10.10.730 129 176 2.6E-18 T 28-03-2018 A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 Gene3D G3DSA:3.90.1530.10 23 128 2.1E-34 T 28-03-2018 A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 SUPERFAMILY SSF109709 122 230 2.33E-33 T 28-03-2018 A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 214 8.2E-59 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 SUPERFAMILY SSF110849 28 131 7.85E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 31 292 1.2E-110 T 28-03-2018 IPR023705 Nucleoid occlusion protein A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 Pfam PF02195 ParB-like nuclease domain 34 127 2.7E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS07270 a3355ae82ec8184bc3a91566bafd3cae 294 SMART SM00470 33 128 4.8E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS07235 91079cfa33bba5fe40f5449afb202ba5 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 24 3.0E-6 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07235 91079cfa33bba5fe40f5449afb202ba5 44 Pfam PF00468 Ribosomal protein L34 1 44 2.6E-24 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07235 91079cfa33bba5fe40f5449afb202ba5 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.3E-21 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07235 91079cfa33bba5fe40f5449afb202ba5 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS07235 91079cfa33bba5fe40f5449afb202ba5 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.349 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS09750 b2faccf4447e08043f94ec9f3298534a 469 PIRSF PIRSF006060 2 467 5.8E-85 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS09750 b2faccf4447e08043f94ec9f3298534a 469 Pfam PF13520 Amino acid permease 14 434 7.1E-43 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 6 434 8.6E-193 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 SUPERFAMILY SSF52540 92 360 4.35E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 1.9E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 SMART SM00382 157 338 5.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 2.7E-5 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 434 8.2E-204 T 28-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS17930 8a58d7a2cddecd979ead43a84801da87 440 Gene3D G3DSA:3.40.50.300 39 354 3.2E-80 T 28-03-2018 A21D_RS09115 7c547948a14888239c4416d2606b65b1 109 SUPERFAMILY SSF46785 5 103 1.57E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09115 7c547948a14888239c4416d2606b65b1 109 Pfam PF01638 HxlR-like helix-turn-helix 15 102 1.8E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type A21D_RS09115 7c547948a14888239c4416d2606b65b1 109 Gene3D G3DSA:1.10.10.10 13 108 8.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11020 469be63c33fb060a4bbefb03d896c6d1 506 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 155 180 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS11020 469be63c33fb060a4bbefb03d896c6d1 506 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 448 2.8E-105 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS11020 469be63c33fb060a4bbefb03d896c6d1 506 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 497 1.7E-217 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 A21D_RS11020 469be63c33fb060a4bbefb03d896c6d1 506 Pfam PF00474 Sodium:solute symporter family 33 448 8.7E-113 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS11020 469be63c33fb060a4bbefb03d896c6d1 506 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 430 450 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 428 1.5E-10 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Gene3D G3DSA:3.50.50.60 243 320 1.8E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 SUPERFAMILY SSF55424 322 443 2.92E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 2.5E-19 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.5E-19 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 2.5E-19 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.5E-19 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.5E-19 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Gene3D G3DSA:3.50.50.60 104 242 2.4E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Gene3D G3DSA:3.30.390.30 324 447 4.5E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 SUPERFAMILY SSF51905 152 317 5.78E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 2.7E-11 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 2.7E-11 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.7E-11 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 2.7E-11 T 28-03-2018 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Gene3D G3DSA:3.50.50.60 12 103 2.7E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 305 1.1E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS11450 14ff3377309ec0d91a3b220ffc56af6b 447 SUPERFAMILY SSF51905 3 196 7.26E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18575 aa13ea71eb0e05ffe6a6d503fae57a7b 93 SUPERFAMILY SSF140404 5 83 1.83E-36 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 A21D_RS18575 aa13ea71eb0e05ffe6a6d503fae57a7b 93 Pfam PF07408 Protein of unknown function (DUF1507) 8 90 8.0E-41 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 A21D_RS18575 aa13ea71eb0e05ffe6a6d503fae57a7b 93 Gene3D G3DSA:1.10.287.750 7 89 1.0E-40 T 28-03-2018 A21D_RS18575 aa13ea71eb0e05ffe6a6d503fae57a7b 93 Hamap MF_01560 UPF0358 protein . 2 92 27.24 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 SUPERFAMILY SSF55781 298 448 2.4E-13 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 SUPERFAMILY SSF55781 152 300 1.2E-9 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 Gene3D G3DSA:3.30.450.40 301 444 5.2E-13 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 Pfam PF00990 Diguanylate cyclase, GGDEF domain 449 595 5.1E-36 T 28-03-2018 IPR000160 GGDEF domain A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 Gene3D G3DSA:3.30.450.40 218 300 3.7E-9 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 SMART SM00267 437 600 7.3E-45 T 28-03-2018 IPR000160 GGDEF domain A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 SUPERFAMILY SSF55073 453 598 7.3E-39 T 28-03-2018 IPR029787 Nucleotide cyclase A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 Gene3D G3DSA:3.30.70.270 445 599 5.0E-43 T 28-03-2018 A21D_RS14395 1e8c54749b12dd6c492d7a797ccf65d0 600 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 444 598 1.6E-37 T 28-03-2018 IPR000160 GGDEF domain A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 SUPERFAMILY SSF51735 6 259 1.53E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 Gene3D G3DSA:3.40.50.720 48 262 1.6E-51 T 28-03-2018 A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 Gene3D G3DSA:3.40.50.720 1 47 9.7E-12 T 28-03-2018 A21D_RS01215 7060ff40dc7d63e2e5455076aefbbb7a 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 259 5.1E-57 T 28-03-2018 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 Gene3D G3DSA:3.40.50.720 171 289 2.2E-27 T 28-03-2018 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 136 1.4E-21 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 Gene3D G3DSA:3.90.180.10 1 170 1.3E-44 T 28-03-2018 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 SUPERFAMILY SSF51735 143 310 1.31E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 Pfam PF00107 Zinc-binding dehydrogenase 178 305 1.4E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 SUPERFAMILY SSF50129 1 177 3.8E-42 T 28-03-2018 IPR011032 GroES-like A21D_RS12225 3a653f0ad4c670f19a47360ec1f6bcbd 349 SMART SM00829 8 343 1.9E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Gene3D G3DSA:3.10.350.10 94 165 2.6E-18 T 28-03-2018 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SUPERFAMILY SSF54106 181 224 7.06E-13 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SUPERFAMILY SSF54106 30 70 6.54E-11 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Pfam PF01476 LysM domain 105 146 2.3E-13 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Pfam PF01476 LysM domain 183 224 1.8E-15 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Pfam PF01476 LysM domain 31 70 6.7E-14 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SUPERFAMILY SSF54001 252 373 7.85E-37 T 28-03-2018 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SMART SM00257 182 225 3.2E-16 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SMART SM00257 104 147 3.0E-15 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SMART SM00257 30 73 2.7E-14 T 28-03-2018 IPR018392 LysM domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Gene3D G3DSA:3.90.1720.10 252 374 5.6E-35 T 28-03-2018 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Pfam PF00877 NlpC/P60 family 269 369 1.1E-27 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Gene3D G3DSA:3.10.350.10 175 240 1.9E-17 T 28-03-2018 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 Gene3D G3DSA:3.10.350.10 23 93 1.8E-14 T 28-03-2018 A21D_RS02685 ed8f3593e52f03d16bc5f0920dc9d7e8 374 SUPERFAMILY SSF54106 103 146 3.01E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS08525 4e5870e0dfa4a5a8d2232c79b7376435 228 Gene3D G3DSA:3.40.50.300 1 227 2.9E-58 T 28-03-2018 A21D_RS08525 4e5870e0dfa4a5a8d2232c79b7376435 228 SMART SM00382 32 221 1.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08525 4e5870e0dfa4a5a8d2232c79b7376435 228 Pfam PF00005 ABC transporter 23 170 1.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08525 4e5870e0dfa4a5a8d2232c79b7376435 228 SUPERFAMILY SSF52540 3 222 1.33E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08525 4e5870e0dfa4a5a8d2232c79b7376435 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 Gene3D G3DSA:3.40.50.150 3 227 7.2E-59 T 28-03-2018 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 SMART SM00650 38 214 2.7E-80 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 22 289 53.815 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 SUPERFAMILY SSF53335 19 289 2.97E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 Pfam PF00398 Ribosomal RNA adenine dimethylase 22 279 5.9E-69 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 54 81 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 287 8.7E-82 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A21D_RS06795 a3c95a051832c772aceb3407252bbe4a 294 Gene3D G3DSA:1.10.8.100 228 289 1.5E-21 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 SUPERFAMILY SSF54821 106 205 3.27E-38 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 Gene3D G3DSA:3.30.1140.32 107 207 6.7E-36 T 28-03-2018 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.029 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 4.2E-94 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 Pfam PF07650 KH domain 37 108 7.1E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 SUPERFAMILY SSF54814 2 105 7.85E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 Gene3D G3DSA:3.30.300.20 17 106 3.1E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.1E-39 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06345 0ecd0cc1d66c34b569dcc430e8b10ef9 213 SMART SM00322 59 124 4.4E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A21D_RS03700 36eb1cd97f810fc4dadf3c7e6aed50af 127 SMART SM00345 15 74 5.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03700 36eb1cd97f810fc4dadf3c7e6aed50af 127 Gene3D G3DSA:1.10.287.100 83 118 7.6E-8 T 28-03-2018 A21D_RS03700 36eb1cd97f810fc4dadf3c7e6aed50af 127 Gene3D G3DSA:1.10.10.10 2 82 5.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03700 36eb1cd97f810fc4dadf3c7e6aed50af 127 SUPERFAMILY SSF46785 4 82 2.82E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03700 36eb1cd97f810fc4dadf3c7e6aed50af 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 Pfam PF00581 Rhodanese-like domain 159 268 1.8E-13 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 Pfam PF00581 Rhodanese-like domain 9 129 1.7E-20 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 Gene3D G3DSA:3.40.250.10 1 153 3.9E-31 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 Gene3D G3DSA:3.40.250.10 154 280 1.2E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 SUPERFAMILY SSF52821 3 153 4.58E-42 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 SMART SM00450 156 273 1.7E-18 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 SMART SM00450 7 133 6.6E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS03160 dcef8f05d47a24606f4c0bf9642a63bc 281 SUPERFAMILY SSF52821 153 276 2.49E-30 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS17675 3a7dace449f87cfe6a57ad037d8d93c9 196 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 1.8E-98 T 28-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B A21D_RS17675 3a7dace449f87cfe6a57ad037d8d93c9 196 SUPERFAMILY SSF52507 6 191 6.54E-29 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS17675 3a7dace449f87cfe6a57ad037d8d93c9 196 Gene3D G3DSA:3.40.50.1950 6 191 3.4E-26 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS17675 3a7dace449f87cfe6a57ad037d8d93c9 196 Pfam PF02441 Flavoprotein 6 154 3.4E-17 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS17675 3a7dace449f87cfe6a57ad037d8d93c9 196 PIRSF PIRSF001390 1 195 4.0E-78 T 28-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B A21D_RS19185 0d5d110b59a6b029637b54759d853704 249 Gene3D G3DSA:3.30.460.10 2 163 5.2E-15 T 28-03-2018 A21D_RS19185 0d5d110b59a6b029637b54759d853704 249 SUPERFAMILY SSF81301 13 76 7.8E-12 T 28-03-2018 A21D_RS19185 0d5d110b59a6b029637b54759d853704 249 Pfam PF01909 Nucleotidyltransferase domain 22 81 3.4E-6 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A21D_RS19185 0d5d110b59a6b029637b54759d853704 249 PIRSF PIRSF000819 1 249 2.8E-60 T 28-03-2018 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 A21D_RS19185 0d5d110b59a6b029637b54759d853704 249 Pfam PF13427 Domain of unknown function (DUF4111) 144 244 1.1E-27 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 A21D_RS15215 1fe64ab1dec477f675328a3ba9c16536 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.203 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15215 1fe64ab1dec477f675328a3ba9c16536 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 6.1E-42 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15215 1fe64ab1dec477f675328a3ba9c16536 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 7.1E-41 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15215 1fe64ab1dec477f675328a3ba9c16536 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15215 1fe64ab1dec477f675328a3ba9c16536 102 SUPERFAMILY SSF141091 1 101 5.89E-40 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 Pfam PF01715 IPP transferase 38 282 4.3E-81 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 Gene3D G3DSA:3.40.50.300 1 195 1.3E-67 T 28-03-2018 A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 302 29.836 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 Gene3D G3DSA:1.10.287.890 199 279 1.0E-30 T 28-03-2018 A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 SUPERFAMILY SSF52540 5 151 2.13E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 SUPERFAMILY SSF52540 4 38 2.33E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 SUPERFAMILY SSF52540 143 226 2.33E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17525 9986b649be703686ba0c51e8b75736a2 310 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 288 7.1E-105 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A21D_RS04980 c6a2f47f6926bd9671d71c9c99c854cc 182 PIRSF PIRSF016661 1 178 5.3E-41 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS04980 c6a2f47f6926bd9671d71c9c99c854cc 182 Pfam PF02632 BioY family 29 171 1.8E-32 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 SUPERFAMILY SSF46894 138 208 6.12E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 Gene3D G3DSA:1.10.10.10 134 207 6.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 SUPERFAMILY SSF52172 1 134 1.39E-31 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 SMART SM00448 2 115 8.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 Pfam PF00072 Response regulator receiver domain 4 116 3.4E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 4.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 4.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 4.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 SMART SM00421 145 202 5.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 8.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13195 634f59e5429aa612e690e3aec218af29 211 Gene3D G3DSA:3.40.50.2300 1 133 1.0E-35 T 28-03-2018 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 SUPERFAMILY SSF53686 1 304 7.73E-100 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 6.7E-126 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 304 1.3E-131 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 Gene3D G3DSA:3.40.50.1100 42 138 5.3E-38 T 28-03-2018 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 Gene3D G3DSA:3.40.50.1100 139 306 8.5E-56 T 28-03-2018 A21D_RS16970 66cf5f9417d3d0b3caeafa1d504d4733 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 292 8.0E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS10770 0935869b41ce4d4e4bff5bdecf7a4c05 182 SUPERFAMILY SSF46785 13 155 1.08E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10770 0935869b41ce4d4e4bff5bdecf7a4c05 182 PIRSF PIRSF006707 1 182 4.0E-42 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type A21D_RS10770 0935869b41ce4d4e4bff5bdecf7a4c05 182 Gene3D G3DSA:1.10.10.10 5 179 5.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 Gene3D G3DSA:3.30.572.10 3 318 1.3E-134 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 Hamap MF_00008 Thymidylate synthase [thyA]. 5 318 40.431 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 PRINTS PR00108 Thymidylate synthase family signature 213 239 1.4E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 PRINTS PR00108 Thymidylate synthase family signature 195 210 1.4E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 PRINTS PR00108 Thymidylate synthase family signature 169 188 1.4E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 PRINTS PR00108 Thymidylate synthase family signature 46 67 1.4E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 PRINTS PR00108 Thymidylate synthase family signature 251 268 1.4E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 ProSitePatterns PS00091 Thymidylate synthase active site. 180 208 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 318 2.7E-163 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 SUPERFAMILY SSF55831 5 318 5.1E-134 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16860 3b759a6cd3f2deb5df1eff291813cc25 318 Pfam PF00303 Thymidylate synthase 7 318 7.8E-123 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS16755 f47815e7e10715947b476eeb97dff336 232 SUPERFAMILY SSF158499 125 191 3.92E-20 T 28-03-2018 IPR006343 DnaD domain A21D_RS16755 f47815e7e10715947b476eeb97dff336 232 Gene3D G3DSA:1.10.10.630 124 196 2.3E-25 T 28-03-2018 IPR034829 DnaD-like domain A21D_RS16755 f47815e7e10715947b476eeb97dff336 232 Pfam PF07261 Replication initiation and membrane attachment 128 196 9.1E-27 T 28-03-2018 IPR006343 DnaD domain A21D_RS16755 f47815e7e10715947b476eeb97dff336 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 128 196 8.0E-25 T 28-03-2018 IPR006343 DnaD domain A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 Pfam PF01595 Domain of unknown function DUF21 3 179 3.4E-47 T 28-03-2018 IPR002550 Domain of unknown function DUF21 A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 SMART SM01091 331 408 3.0E-14 T 28-03-2018 IPR005170 Transporter-associated domain A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 Pfam PF03471 Transporter associated domain 332 406 1.6E-13 T 28-03-2018 IPR005170 Transporter-associated domain A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 Pfam PF00571 CBS domain 266 313 3.2E-4 T 28-03-2018 IPR000644 CBS domain A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 Gene3D G3DSA:3.20.20.70 118 328 2.2E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 SUPERFAMILY SSF56176 327 405 4.36E-13 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 SUPERFAMILY SSF54631 182 315 9.1E-24 T 28-03-2018 A21D_RS08345 6f8080b1025b043914b33be0c4590146 416 Gene3D G3DSA:3.30.465.10 329 407 9.3E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS00655 f71a2358c8e4ce8f88c37fcb05d609c0 319 SUPERFAMILY SSF142338 6 314 4.71E-103 T 28-03-2018 A21D_RS00655 f71a2358c8e4ce8f88c37fcb05d609c0 319 Gene3D G3DSA:3.40.50.10680 85 319 2.9E-60 T 28-03-2018 A21D_RS00655 f71a2358c8e4ce8f88c37fcb05d609c0 319 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 317 1.9E-116 T 28-03-2018 IPR010119 Gluconeogenesis factor A21D_RS00655 f71a2358c8e4ce8f88c37fcb05d609c0 319 Pfam PF01933 Uncharacterised protein family UPF0052 9 294 4.5E-103 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A21D_RS00655 f71a2358c8e4ce8f88c37fcb05d609c0 319 Hamap MF_00973 Gluconeogenesis factor. 5 319 35.163 T 28-03-2018 IPR010119 Gluconeogenesis factor A21D_RS06715 a47cee83937bfaa4b8d73aef9b4dd07c 86 Pfam PF01479 S4 domain 1 47 2.0E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS06715 a47cee83937bfaa4b8d73aef9b4dd07c 86 SUPERFAMILY SSF55174 1 79 6.67E-19 T 28-03-2018 A21D_RS06715 a47cee83937bfaa4b8d73aef9b4dd07c 86 SMART SM00363 1 64 2.3E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS06715 a47cee83937bfaa4b8d73aef9b4dd07c 86 PIRSF PIRSF038881 1 86 1.3E-30 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type A21D_RS06715 a47cee83937bfaa4b8d73aef9b4dd07c 86 Gene3D G3DSA:3.10.290.10 1 86 5.2E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 Gene3D G3DSA:3.20.20.70 18 271 6.8E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 Pfam PF01680 SOR/SNZ family 7 212 2.6E-105 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 292 1.7E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 SUPERFAMILY SSF51366 18 268 1.13E-67 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 PIRSF PIRSF029271 1 294 2.5E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS07175 48e294efcd796b82248f6510e41a32e3 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 52.085 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 SUPERFAMILY SSF52954 330 420 3.62E-25 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 Gene3D G3DSA:3.40.50.800 327 423 2.3E-20 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.155 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 1.6E-157 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 Gene3D G3DSA:3.30.930.10 1 324 2.0E-71 T 28-03-2018 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 Pfam PF13393 Histidyl-tRNA synthetase 8 313 2.2E-48 T 28-03-2018 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 Pfam PF03129 Anticodon binding domain 332 420 1.9E-16 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 SUPERFAMILY SSF55681 3 319 5.77E-98 T 28-03-2018 A21D_RS15355 689c8abe5cfe19c10dc33c60d6175c61 429 PIRSF PIRSF001549 1 422 8.5E-125 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 321 5.9E-146 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 PIRSF PIRSF004532 1 321 9.5E-152 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 Gene3D G3DSA:3.30.540.10 1 155 1.7E-59 T 28-03-2018 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 Gene3D G3DSA:3.30.540.10 156 321 1.1E-59 T 28-03-2018 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 SUPERFAMILY SSF56655 2 313 4.3E-113 T 28-03-2018 A21D_RS04675 47ce8c2b123a5baada7c377b15ac4dc9 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 2.3E-146 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 SUPERFAMILY SSF56512 4 360 6.67E-166 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 Pfam PF02898 Nitric oxide synthase, oxygenase domain 5 360 2.7E-163 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 Gene3D G3DSA:3.90.340.10 2 127 7.2E-45 T 28-03-2018 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 66 73 - T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 Gene3D G3DSA:3.90.1230.10 194 304 2.2E-50 T 28-03-2018 A21D_RS12380 53b75df2be04e540e3b1e14d6315f4d0 363 PIRSF PIRSF037219 2 362 6.2E-180 T 28-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 A21D_RS19325 c229bcac9a2b7696dc2ecf851bbd3090 405 Pfam PF01610 Transposase 151 391 8.0E-66 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain A21D_RS19325 c229bcac9a2b7696dc2ecf851bbd3090 405 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 35 80 3.9E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger A21D_RS19325 c229bcac9a2b7696dc2ecf851bbd3090 405 Gene3D G3DSA:1.10.10.60 104 140 0.0013 T 28-03-2018 A21D_RS19325 c229bcac9a2b7696dc2ecf851bbd3090 405 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 136 5.4E-11 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain A21D_RS19325 c229bcac9a2b7696dc2ecf851bbd3090 405 Gene3D G3DSA:2.60.260.40 25 103 7.7E-4 T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 SMART SM00354 3 73 9.6E-38 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 9.1E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 Gene3D G3DSA:3.40.50.2300 168 332 8.3E-47 T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 Gene3D G3DSA:1.10.260.40 4 59 2.5E-25 T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 SUPERFAMILY SSF53822 63 332 3.93E-85 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 SUPERFAMILY SSF47413 3 61 2.15E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 Gene3D G3DSA:3.40.50.2300 60 167 5.3E-29 T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 Pfam PF13377 Periplasmic binding protein-like domain 171 331 1.4E-32 T 28-03-2018 A21D_RS14345 4b19378e2a9e9a3465266ee3ab2e970b 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 332 2.4E-155 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 165 1.3E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 SUPERFAMILY SSF48179 169 291 1.25E-37 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 290 6.1E-35 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 SUPERFAMILY SSF51735 9 169 1.89E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 PIRSF PIRSF000103 5 293 2.8E-69 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 Gene3D G3DSA:1.10.1040.10 170 294 3.2E-33 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS04040 42c4947e66efaae8623b6da6410d1324 295 Gene3D G3DSA:3.40.50.720 8 169 3.5E-29 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 6.5E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Gene3D G3DSA:3.30.300.30 416 522 3.2E-27 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Gene3D G3DSA:3.40.50.980 180 331 6.7E-44 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Gene3D G3DSA:3.40.50.980 7 179 7.8E-40 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 SUPERFAMILY SSF56801 6 517 1.22E-149 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Gene3D G3DSA:2.30.38.10 332 414 9.7E-26 T 28-03-2018 A21D_RS09500 758c13b84398a50f2daa6d2f277190c7 524 Pfam PF00501 AMP-binding enzyme 18 421 3.1E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 SMART SM00100 8 126 0.0011 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 Pfam PF13545 Crp-like helix-turn-helix domain 148 219 1.3E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 Gene3D G3DSA:1.10.10.10 136 222 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 Gene3D G3DSA:2.60.120.10 1 135 2.0E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 SMART SM00419 165 213 7.8E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 ProSitePatterns PS00042 Crp-type HTH domain signature. 173 196 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 SUPERFAMILY SSF46785 145 230 5.65E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 SUPERFAMILY SSF51206 16 140 9.69E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 171 187 8.9E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 202 8.9E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS14960 4e4615590cb71b957d15967dd701371c 234 Pfam PF00027 Cyclic nucleotide-binding domain 26 113 2.4E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS13220 4568727ee68c80e972cb681513831738 725 SUPERFAMILY SSF53955 53 265 1.24E-74 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS13220 4568727ee68c80e972cb681513831738 725 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 75 608 2.3E-164 T 28-03-2018 A21D_RS13220 4568727ee68c80e972cb681513831738 725 SUPERFAMILY SSF56601 272 623 1.63E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS13220 4568727ee68c80e972cb681513831738 725 SUPERFAMILY SSF56601 221 243 1.63E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS13220 4568727ee68c80e972cb681513831738 725 Pfam PF00905 Penicillin binding protein transpeptidase domain 331 604 1.2E-31 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS13220 4568727ee68c80e972cb681513831738 725 Pfam PF00912 Transglycosylase 65 239 5.5E-64 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS13220 4568727ee68c80e972cb681513831738 725 Gene3D G3DSA:1.10.3810.10 57 256 1.0E-76 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS13220 4568727ee68c80e972cb681513831738 725 Gene3D G3DSA:3.40.710.10 267 629 1.7E-84 T 28-03-2018 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 657 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Gene3D G3DSA:4.10.860.10 602 659 1.4E-15 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Pfam PF00271 Helicase conserved C-terminal domain 434 544 9.5E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SMART SM00487 9 425 4.8E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Pfam PF12344 Ultra-violet resistance protein B 551 593 2.5E-20 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Pfam PF04851 Type III restriction enzyme, res subunit 11 92 6.1E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SUPERFAMILY SSF52540 3 414 1.67E-140 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Gene3D G3DSA:3.40.50.300 416 588 3.1E-32 T 28-03-2018 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SUPERFAMILY SSF52540 32 80 1.08E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SUPERFAMILY SSF52540 469 594 1.08E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 659 44.298 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SMART SM00490 459 545 2.8E-21 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Pfam PF02151 UvrB/uvrC motif 624 658 9.6E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 SUPERFAMILY SSF46600 613 657 3.79E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS00740 3e6d99e7cea4b566850d98e79090b7bd 660 Gene3D G3DSA:3.40.50.300 10 415 7.7E-32 T 28-03-2018 A21D_RS14990 6191eb65c8a9bf81cfad8b6ebeb785ec 106 Pfam PF09685 Domain of unknown function (DUF4870) 6 104 1.5E-8 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 A21D_RS14990 6191eb65c8a9bf81cfad8b6ebeb785ec 106 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 49 8.0E-14 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Gene3D G3DSA:3.40.228.10 294 565 3.9E-49 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SUPERFAMILY SSF50692 865 950 2.69E-16 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SUPERFAMILY SSF50692 982 1031 2.69E-16 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SUPERFAMILY SSF53706 134 184 1.1E-112 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SUPERFAMILY SSF53706 59 102 1.1E-112 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SUPERFAMILY SSF53706 230 766 1.1E-112 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Pfam PF01568 Molydopterin dinucleotide binding domain 880 967 6.6E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Gene3D G3DSA:3.40.50.740 155 293 1.6E-11 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Gene3D G3DSA:2.40.40.20 842 1032 3.4E-25 T 28-03-2018 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Pfam PF00384 Molybdopterin oxidoreductase 153 183 8.2E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Pfam PF00384 Molybdopterin oxidoreductase 261 678 1.9E-22 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 SMART SM00926 57 150 1.4E-4 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS14945 dc8d7d79abae7c60027cee757654e144 1033 Gene3D G3DSA:2.20.25.90 51 154 2.6E-12 T 28-03-2018 A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 SUPERFAMILY SSF54211 1 170 2.28E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 Gene3D G3DSA:3.30.230.10 1 173 5.1E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 Gene3D G3DSA:3.30.70.890 174 316 5.5E-45 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 PIRSF PIRSF015950 1 324 3.0E-123 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 Pfam PF00288 GHMP kinases N terminal domain 90 147 2.9E-5 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 4 305 2.6E-110 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 A21D_RS05370 9ae8d8fca14bcf5704f381424cad8dea 324 SUPERFAMILY SSF55060 175 321 3.02E-42 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 376 1.8E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 3.2E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 SUPERFAMILY SSF47203 228 387 1.61E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 PIRSF PIRSF016578 6 108 6.0E-4 T 28-03-2018 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 PIRSF PIRSF016578 214 380 1.3E-5 T 28-03-2018 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 PIRSF PIRSF016578 127 196 0.068 T 28-03-2018 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Gene3D G3DSA:1.20.140.10 219 390 5.2E-55 T 28-03-2018 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Gene3D G3DSA:1.10.540.10 1 120 6.2E-40 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 SUPERFAMILY SSF56645 1 243 1.13E-87 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 3.5E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS11515 4afd4d4aa5905ec38dd75a0b4b499411 404 Gene3D G3DSA:2.40.110.10 121 218 4.4E-37 T 28-03-2018 A21D_RS15775 851da39bf866f26608a9e427d5b747ce 239 PIRSF PIRSF018637 3 233 8.5E-78 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A21D_RS15775 851da39bf866f26608a9e427d5b747ce 239 Gene3D G3DSA:3.40.50.150 1 165 5.7E-14 T 28-03-2018 A21D_RS15775 851da39bf866f26608a9e427d5b747ce 239 SUPERFAMILY SSF53335 7 96 1.02E-6 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS15775 851da39bf866f26608a9e427d5b747ce 239 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 22 220 4.5E-67 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 SMART SM00382 345 490 6.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 673 681 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 SUPERFAMILY SSF52540 307 587 3.71E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Gene3D G3DSA:1.10.4060.10 118 208 9.0E-25 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Hamap MF_01973 Lon protease [lon]. 8 769 71.029 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 TIGRFAM TIGR00763 lon: endopeptidase La 9 768 6.1E-304 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PIRSF PIRSF001174 1 772 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Gene3D G3DSA:3.40.50.300 310 488 1.8E-34 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 SUPERFAMILY SSF54211 592 767 1.48E-56 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 197 1.2E-37 T 28-03-2018 IPR003111 Lon, substrate-binding domain A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 SUPERFAMILY SSF88697 7 197 2.98E-44 T 28-03-2018 IPR015947 PUA-like domain A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Gene3D G3DSA:3.30.230.10 574 778 8.4E-68 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 SMART SM00464 7 199 1.8E-62 T 28-03-2018 IPR003111 Lon, substrate-binding domain A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 567 769 1.9E-97 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 592 608 1.8E-54 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 670 689 1.8E-54 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 372 1.8E-54 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 700 719 1.8E-54 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 723 741 1.8E-54 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Gene3D G3DSA:2.30.130.40 5 116 6.5E-24 T 28-03-2018 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 349 486 4.0E-25 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS15090 f0501e5e5fc995010f8378cc502c4375 778 Gene3D G3DSA:1.10.8.60 489 573 1.5E-31 T 28-03-2018 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 3.1E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 4.4E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 SUPERFAMILY SSF56645 2 240 7.98E-80 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 SUPERFAMILY SSF47203 226 378 2.58E-56 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Gene3D G3DSA:1.20.140.10 218 378 3.9E-61 T 28-03-2018 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Gene3D G3DSA:1.10.540.10 1 121 1.9E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 PIRSF PIRSF016578 5 362 8.3E-16 T 28-03-2018 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Gene3D G3DSA:2.40.110.10 122 217 5.9E-38 T 28-03-2018 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 4.5E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12550 d90f7bddd93f83f51af799895216bdd6 378 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 350 7.0E-77 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 144 5.9E-39 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 SUPERFAMILY SSF53756 4 353 9.99E-89 T 28-03-2018 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 Gene3D G3DSA:3.40.50.2000 186 343 1.5E-20 T 28-03-2018 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 Gene3D G3DSA:3.40.50.2000 1 185 6.5E-40 T 28-03-2018 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 355 28.945 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS12865 e3124f7c05df2844cd9314af315c37d3 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 338 1.7E-28 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A21D_RS01510 8e593e8d6bc6290139d19bbfa1e341e7 134 SUPERFAMILY SSF55811 11 131 5.15E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS01510 8e593e8d6bc6290139d19bbfa1e341e7 134 Pfam PF00293 NUDIX domain 14 129 3.4E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS01510 8e593e8d6bc6290139d19bbfa1e341e7 134 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A21D_RS01510 8e593e8d6bc6290139d19bbfa1e341e7 134 Gene3D G3DSA:3.90.79.10 2 131 1.9E-17 T 28-03-2018 A21D_RS04845 8fc5b2a23b9e204cb4cfd25d9ccec846 102 Pfam PF17261 Family of unknown function (DUF5327) 1 102 1.9E-21 T 28-03-2018 IPR035218 Protein of unknown function DUF5327 A21D_RS04845 8fc5b2a23b9e204cb4cfd25d9ccec846 102 ProDom PD705231 YWDI GROUP-SPECIFIC 1 102 9.0E-6 T 28-03-2018 IPR035218 Protein of unknown function DUF5327 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Gene3D G3DSA:3.30.300.30 455 560 6.1E-29 T 28-03-2018 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Gene3D G3DSA:2.30.38.10 371 453 3.2E-29 T 28-03-2018 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 SUPERFAMILY SSF56801 10 554 1.44E-167 T 28-03-2018 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Pfam PF00501 AMP-binding enzyme 32 459 1.6E-122 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Gene3D G3DSA:3.40.50.980 218 370 1.4E-52 T 28-03-2018 A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 544 3.5E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS14785 c3a838e10bd3a3666e013da919d0c274 561 Gene3D G3DSA:3.40.50.980 22 217 2.4E-43 T 28-03-2018 A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 242 9.1E-55 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 SUPERFAMILY SSF117143 91 223 3.53E-36 T 28-03-2018 A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 Pfam PF00460 Flagella basal body rod protein 5 35 1.9E-11 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 261 2.2E-22 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 150 244 2.1E-30 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A21D_RS17905 90c4919a5e621e642a435da015b42f6c 263 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 134 3.7E-40 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 Gene3D G3DSA:2.10.109.10 89 206 5.2E-26 T 28-03-2018 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 Gene3D G3DSA:1.10.10.10 1 70 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 7.7E-76 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 34.007 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 SUPERFAMILY SSF46785 3 70 6.02E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 1.1E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 1.1E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 1.1E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 Pfam PF00717 Peptidase S24-like 125 190 2.1E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 Pfam PF01726 LexA DNA binding domain 1 65 7.4E-28 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A21D_RS17180 d51962fe73c52d5014ee6feeea070fb1 207 SUPERFAMILY SSF51306 85 204 6.45E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS18535 7332f7f33e91206f1bc7bc0a6b3fb4a0 104 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 7 104 4.1E-46 T 28-03-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A21D_RS18535 7332f7f33e91206f1bc7bc0a6b3fb4a0 104 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 23 95 1.0E-14 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Gene3D G3DSA:3.30.70.20 287 321 0.0044 T 28-03-2018 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Gene3D G3DSA:3.40.50.10420 64 138 2.8E-9 T 28-03-2018 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Gene3D G3DSA:3.40.50.10420 139 286 2.0E-43 T 28-03-2018 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Pfam PF13183 4Fe-4S dicluster domain 309 376 2.7E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 SUPERFAMILY SSF46548 306 392 4.45E-15 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Pfam PF11870 Domain of unknown function (DUF3390) 384 470 2.6E-22 T 28-03-2018 IPR024569 4Fe-4S binding protein, C-terminal A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Gene3D G3DSA:3.30.70.20 322 436 2.7E-8 T 28-03-2018 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 474 67.439 T 28-03-2018 IPR022825 Lactate utilization protein B A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 Pfam PF02589 LUD domain 70 294 3.0E-54 T 28-03-2018 IPR003741 LUD domain A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 454 2.2E-194 T 28-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 SUPERFAMILY SSF100950 64 89 4.18E-39 T 28-03-2018 A21D_RS03615 a21fb723d9f75a1a55244ce0bc2e4084 478 SUPERFAMILY SSF100950 135 295 4.18E-39 T 28-03-2018 A21D_RS06835 67a9ae9ad09367f31863e66921f38b87 247 SUPERFAMILY SSF53335 6 199 7.21E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS06835 67a9ae9ad09367f31863e66921f38b87 247 Pfam PF05175 Methyltransferase small domain 19 126 1.8E-10 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A21D_RS06835 67a9ae9ad09367f31863e66921f38b87 247 Gene3D G3DSA:3.40.50.150 10 247 5.5E-39 T 28-03-2018 A21D_RS02220 f11262abf4643d55f826f58f3eeef91d 148 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 29 116 1.1E-7 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 A21D_RS02220 f11262abf4643d55f826f58f3eeef91d 148 SUPERFAMILY SSF52309 1 135 1.95E-17 T 28-03-2018 A21D_RS02220 f11262abf4643d55f826f58f3eeef91d 148 Gene3D G3DSA:3.40.50.450 1 147 3.3E-30 T 28-03-2018 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 Gene3D G3DSA:3.40.605.10 13 242 1.2E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 Gene3D G3DSA:3.40.309.10 243 422 1.7E-61 T 28-03-2018 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 PIRSF PIRSF036492 7 470 2.6E-187 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 251 262 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 SUPERFAMILY SSF53720 17 453 1.19E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 223 230 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS16255 7c58611aff9316c8f284749f7ab00ad2 470 Pfam PF00171 Aldehyde dehydrogenase family 33 442 4.4E-88 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 Gene3D G3DSA:1.10.1200.10 1 78 3.4E-24 T 28-03-2018 A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 5.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 3.9E-34 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.537 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 75 0.004 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A21D_RS18100 f6df3d79fa09044f6ba0abfd9a5a1907 78 SUPERFAMILY SSF47336 2 77 2.62E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS08720 670550433491f2356dcf031e3c41e461 194 PIRSF PIRSF004682 1 177 1.4E-55 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A21D_RS08720 670550433491f2356dcf031e3c41e461 194 Pfam PF13242 HAD-hyrolase-like 104 151 4.1E-12 T 28-03-2018 A21D_RS08720 670550433491f2356dcf031e3c41e461 194 SUPERFAMILY SSF56784 2 173 5.37E-41 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08720 670550433491f2356dcf031e3c41e461 194 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 149 1.4E-31 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A21D_RS08720 670550433491f2356dcf031e3c41e461 194 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 147 2.3E-41 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A21D_RS08720 670550433491f2356dcf031e3c41e461 194 Gene3D G3DSA:3.40.50.1000 1 188 3.4E-27 T 28-03-2018 IPR023214 HAD-like domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 Gene3D G3DSA:3.30.465.10 352 445 6.5E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 Pfam PF01595 Domain of unknown function DUF21 9 199 3.3E-47 T 28-03-2018 IPR002550 Domain of unknown function DUF21 A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 SUPERFAMILY SSF54631 203 338 3.05E-25 T 28-03-2018 A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 SMART SM01091 350 435 1.7E-16 T 28-03-2018 IPR005170 Transporter-associated domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 SUPERFAMILY SSF56176 349 439 4.36E-16 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 Pfam PF03471 Transporter associated domain 351 434 1.5E-13 T 28-03-2018 IPR005170 Transporter-associated domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 SMART SM00116 287 335 0.06 T 28-03-2018 IPR000644 CBS domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 SMART SM00116 225 274 38.0 T 28-03-2018 IPR000644 CBS domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 Pfam PF00571 CBS domain 289 335 4.9E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS09560 55e319642bf4e1c1e6915369a2ef85a8 445 Gene3D G3DSA:3.20.20.70 57 351 1.4E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Gene3D G3DSA:3.30.300.30 457 569 2.9E-27 T 28-03-2018 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Gene3D G3DSA:3.40.50.980 40 217 2.2E-42 T 28-03-2018 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Pfam PF00501 AMP-binding enzyme 57 461 6.9E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 SUPERFAMILY SSF56801 24 561 3.4E-159 T 28-03-2018 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Gene3D G3DSA:2.30.38.10 372 454 8.7E-19 T 28-03-2018 A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 548 7.7E-23 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS06965 d06cdd06c868bfd1230bb2da6f29e7cc 571 Gene3D G3DSA:3.40.50.980 218 371 9.6E-41 T 28-03-2018 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 16 215 7.1E-23 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 324 466 8.5E-43 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 SUPERFAMILY SSF100950 229 498 8.38E-85 T 28-03-2018 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 SUPERFAMILY SSF100950 6 225 1.62E-63 T 28-03-2018 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 Gene3D G3DSA:3.40.1080.10 15 240 6.0E-32 T 28-03-2018 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 14 497 1.4E-230 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 A21D_RS08715 2edab3e1b6f95bf4a7c0beb8573c7d23 504 Gene3D G3DSA:3.40.1080.10 241 504 7.5E-62 T 28-03-2018 A21D_RS10195 92d26b5cb7df44596407e47e82067405 390 Pfam PF01098 Cell cycle protein 7 381 3.0E-89 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A21D_RS10195 92d26b5cb7df44596407e47e82067405 390 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 339 363 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 SUPERFAMILY SSF46785 2 54 1.41E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 SMART SM00345 2 50 9.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 50 1.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 Gene3D G3DSA:3.40.1410.10 54 216 1.1E-24 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 Gene3D G3DSA:1.10.10.10 1 52 3.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 SMART SM00866 72 210 6.1E-9 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 10 24 9.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 40 9.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 SUPERFAMILY SSF64288 39 215 4.87E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08165 bf54a3eb69caccb9f26e762277512d61 216 Pfam PF07702 UTRA domain 74 210 6.9E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS16525 3dfe26a1ce9a247d2b6afc0fda97e9d4 222 Pfam PF02224 Cytidylate kinase 7 219 2.7E-79 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A21D_RS16525 3dfe26a1ce9a247d2b6afc0fda97e9d4 222 Hamap MF_00238 Cytidylate kinase [cmk]. 5 222 33.235 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A21D_RS16525 3dfe26a1ce9a247d2b6afc0fda97e9d4 222 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 216 1.0E-84 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A21D_RS16525 3dfe26a1ce9a247d2b6afc0fda97e9d4 222 Gene3D G3DSA:3.40.50.300 1 221 2.7E-54 T 28-03-2018 A21D_RS16525 3dfe26a1ce9a247d2b6afc0fda97e9d4 222 SUPERFAMILY SSF52540 5 217 1.61E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Gene3D G3DSA:4.10.1250.10 243 286 1.6E-16 T 28-03-2018 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 264 5.2E-96 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Gene3D G3DSA:3.30.1360.120 4 132 4.9E-34 T 28-03-2018 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Gene3D G3DSA:2.40.30.110 288 371 3.8E-24 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 SUPERFAMILY SSF103025 3 288 2.13E-99 T 28-03-2018 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 SUPERFAMILY SSF101790 280 370 1.8E-23 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 369 48.267 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Gene3D G3DSA:3.30.1360.120 133 242 4.5E-32 T 28-03-2018 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 273 363 6.8E-25 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 369 1.3E-139 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A21D_RS16000 0c23f1d913b6f1a1aded6db17794c0d6 371 PIRSF PIRSF006487 1 371 4.1E-101 T 28-03-2018 A21D_RS14780 ed3d54625bf7fcb4472fa4dd0bf21058 138 Pfam PF03994 Domain of Unknown Function (DUF350) 21 71 6.6E-12 T 28-03-2018 IPR007140 Protein of unknown function DUF350 A21D_RS14780 ed3d54625bf7fcb4472fa4dd0bf21058 138 Pfam PF03994 Domain of Unknown Function (DUF350) 83 137 4.5E-15 T 28-03-2018 IPR007140 Protein of unknown function DUF350 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 PIRSF PIRSF001553 1 291 1.3E-132 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 28-03-2018 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 28-03-2018 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 28-03-2018 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 28-03-2018 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 Pfam PF00549 CoA-ligase 151 262 4.3E-19 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 SMART SM00881 4 100 5.6E-34 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 4.2E-144 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 SUPERFAMILY SSF51735 1 122 3.29E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 Gene3D G3DSA:3.40.50.720 1 119 6.2E-45 T 28-03-2018 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 Pfam PF02629 CoA binding domain 6 99 2.7E-30 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 SUPERFAMILY SSF52210 123 285 6.41E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.167 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A21D_RS18000 b47efbd36649aa619cf2292d909894b2 300 Gene3D G3DSA:3.40.50.261 120 300 3.7E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A21D_RS15915 658295478422fe62b14cac31b5af1290 70 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 59 2.3E-27 T 28-03-2018 IPR009256 Protein of unknown function DUF910 A21D_RS15915 658295478422fe62b14cac31b5af1290 70 Gene3D G3DSA:1.10.287.760 1 65 5.4E-28 T 28-03-2018 IPR023164 YqgQ-like domain A21D_RS15915 658295478422fe62b14cac31b5af1290 70 SUPERFAMILY SSF158379 1 59 7.06E-23 T 28-03-2018 IPR023164 YqgQ-like domain A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 Pfam PF01565 FAD binding domain 17 151 1.4E-26 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 SUPERFAMILY SSF56176 4 181 9.81E-45 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 Gene3D G3DSA:3.30.465.10 71 186 4.1E-25 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 Pfam PF04030 D-arabinono-1,4-lactone oxidase 175 426 7.0E-77 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 Gene3D G3DSA:3.40.462.10 187 396 5.2E-38 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 Gene3D G3DSA:3.30.43.10 1 70 8.5E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 PIRSF PIRSF000136 1 433 2.1E-128 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 A21D_RS08995 b3a54e712ad9d35610b44b1db4497a7d 447 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 6 428 8.5E-118 T 28-03-2018 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 Gene3D G3DSA:3.40.50.300 2 334 1.0E-79 T 28-03-2018 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 291 4.6E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 2.9E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 Pfam PF00005 ABC transporter 26 182 2.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 SUPERFAMILY SSF52540 5 254 7.62E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01330 10fa4c6f9df20fd451a6bf2df408c702 339 SMART SM00382 34 232 5.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05025 4a1b1d8759cd6391f0c24a05bff3af25 126 SUPERFAMILY SSF55729 3 116 1.39E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS05025 4a1b1d8759cd6391f0c24a05bff3af25 126 Pfam PF13302 Acetyltransferase (GNAT) domain 8 92 2.8E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS05025 4a1b1d8759cd6391f0c24a05bff3af25 126 Gene3D G3DSA:3.40.630.30 2 124 5.2E-28 T 28-03-2018 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 PIRSF PIRSF000194 1 162 1.2E-58 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 Gene3D G3DSA:3.40.430.10 1 162 1.4E-53 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 Pfam PF00186 Dihydrofolate reductase 1 161 3.3E-62 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 SUPERFAMILY SSF53597 1 162 2.09E-56 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 PRINTS PR00070 Dihydrofolate reductase signature 13 23 2.3E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 PRINTS PR00070 Dihydrofolate reductase signature 40 51 2.3E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 PRINTS PR00070 Dihydrofolate reductase signature 93 107 2.3E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS16865 e22cf6765216e981b45f6e3c16d5c42a 162 PRINTS PR00070 Dihydrofolate reductase signature 27 35 2.3E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 PIRSF PIRSF002465 1 331 2.9E-129 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 Gene3D G3DSA:3.40.718.10 1 329 7.3E-109 T 28-03-2018 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 SUPERFAMILY SSF53659 1 328 5.76E-106 T 28-03-2018 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 Pfam PF02504 Fatty acid synthesis protein 1 318 2.2E-124 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 331 1.3E-134 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A21D_RS18115 7cb8668ec1b39c908db582673cd59486 335 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 150.836 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SMART SM00316 644 715 4.9E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Gene3D G3DSA:1.10.3500.10 102 346 1.4E-84 T 28-03-2018 IPR023323 Tex-like domain A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Pfam PF00575 S1 RNA binding domain 644 714 4.0E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Pfam PF12836 Helix-hairpin-helix motif 483 547 9.6E-25 T 28-03-2018 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SUPERFAMILY SSF47781 553 627 3.33E-16 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Pfam PF16921 Tex protein YqgF-like domain 318 443 1.1E-55 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SMART SM00732 318 416 6.9E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Gene3D G3DSA:1.10.10.650 2 101 6.0E-31 T 28-03-2018 IPR023319 Tex-like protein, HTH domain A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Gene3D G3DSA:1.10.150.310 491 625 4.7E-45 T 28-03-2018 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SUPERFAMILY SSF158832 4 313 7.19E-112 T 28-03-2018 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Gene3D G3DSA:1.10.3500.10 347 490 4.4E-40 T 28-03-2018 IPR023323 Tex-like domain A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SUPERFAMILY SSF53098 314 461 1.97E-51 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SUPERFAMILY SSF50249 631 714 1.19E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Pfam PF09371 Tex-like protein N-terminal domain 9 192 8.0E-68 T 28-03-2018 IPR018974 Tex-like protein, N-terminal A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 Gene3D G3DSA:2.40.50.140 635 718 9.4E-23 T 28-03-2018 A21D_RS10070 c07c70925f4df4aa8c76027442684bee 718 SUPERFAMILY SSF47781 462 549 1.67E-25 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS01705 db145fbf90312dce72cc1daa47a92131 399 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 54 230 7.1E-54 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 A21D_RS01705 db145fbf90312dce72cc1daa47a92131 399 Gene3D G3DSA:1.20.1170.10 46 391 3.8E-42 T 28-03-2018 A21D_RS01705 db145fbf90312dce72cc1daa47a92131 399 SUPERFAMILY SSF58100 45 249 1.15E-79 T 28-03-2018 A21D_RS01705 db145fbf90312dce72cc1daa47a92131 399 SUPERFAMILY SSF58100 275 389 1.15E-79 T 28-03-2018 A21D_RS16035 cb2f63b185efa2073d13ec8e41c7bfa4 175 Pfam PF11085 Conserved membrane protein YqhR 4 166 1.1E-61 T 28-03-2018 IPR024563 Uncharacterised protein family YqhR A21D_RS16035 cb2f63b185efa2073d13ec8e41c7bfa4 175 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 2 162 7.0E-44 T 28-03-2018 IPR024563 Uncharacterised protein family YqhR A21D_RS12755 941886b3319585b8ea5021694984b095 213 SMART SM00448 2 115 3.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS12755 941886b3319585b8ea5021694984b095 213 Gene3D G3DSA:3.40.50.2300 1 133 3.0E-38 T 28-03-2018 A21D_RS12755 941886b3319585b8ea5021694984b095 213 SUPERFAMILY SSF46894 147 211 9.52E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS12755 941886b3319585b8ea5021694984b095 213 Pfam PF00072 Response regulator receiver domain 4 115 1.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS12755 941886b3319585b8ea5021694984b095 213 Gene3D G3DSA:1.10.10.10 134 211 8.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12755 941886b3319585b8ea5021694984b095 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS12755 941886b3319585b8ea5021694984b095 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS12755 941886b3319585b8ea5021694984b095 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS12755 941886b3319585b8ea5021694984b095 213 SUPERFAMILY SSF52172 1 131 1.18E-34 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS12755 941886b3319585b8ea5021694984b095 213 SMART SM00421 149 206 2.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS12755 941886b3319585b8ea5021694984b095 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 2.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 PIRSF PIRSF006769 1 362 5.5E-131 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 1.2E-122 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 Gene3D G3DSA:3.40.430.10 126 368 4.3E-74 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 Pfam PF01872 RibD C-terminal domain 148 355 2.1E-54 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 SUPERFAMILY SSF53597 146 359 5.0E-61 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 SUPERFAMILY SSF53927 4 143 2.01E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 355 2.9E-68 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 Gene3D G3DSA:3.40.140.10 1 125 4.6E-32 T 28-03-2018 A21D_RS03850 0796e80a131e0fa09c0f560c05c4baf1 369 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 100 1.1E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A21D_RS19375 d0255a3a8c7b481a79641817f4c5b60a 255 Gene3D G3DSA:3.90.850.10 8 252 7.9E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS19375 d0255a3a8c7b481a79641817f4c5b60a 255 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 41 244 1.6E-78 T 28-03-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 A21D_RS19375 d0255a3a8c7b481a79641817f4c5b60a 255 SUPERFAMILY SSF56529 41 245 3.27E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS19375 d0255a3a8c7b481a79641817f4c5b60a 255 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 43 245 2.5E-43 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 SMART SM00382 28 206 3.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 Pfam PF00005 ABC transporter 20 158 4.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 SUPERFAMILY SSF52540 3 225 1.51E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 Pfam PF13732 Domain of unknown function (DUF4162) 211 299 1.8E-9 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 Gene3D G3DSA:3.40.50.300 1 292 4.0E-61 T 28-03-2018 A21D_RS11650 699f75f1315c67e96fd1a3e67a2cf202 302 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 SUPERFAMILY SSF82708 159 203 8.04E-8 T 28-03-2018 IPR001374 R3H domain GO:0003676 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Pfam PF13083 KH domain 64 127 1.8E-15 T 28-03-2018 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 SMART SM00393 126 204 1.8E-14 T 28-03-2018 IPR001374 R3H domain GO:0003676 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 SMART SM01245 5 57 5.7E-21 T 28-03-2018 IPR032782 Jag, N-terminal A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Pfam PF01424 R3H domain 144 203 1.8E-14 T 28-03-2018 IPR001374 R3H domain GO:0003676 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Pfam PF14804 Jag N-terminus 7 55 4.0E-20 T 28-03-2018 IPR032782 Jag, N-terminal A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Gene3D G3DSA:3.30.300.20 58 135 5.7E-20 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Gene3D G3DSA:3.30.1370.50 137 204 1.1E-19 T 28-03-2018 IPR001374 R3H domain GO:0003676 A21D_RS07250 0c34533bcecc339b461df685d15fa251 204 Gene3D G3DSA:3.30.30.80 3 54 7.0E-21 T 28-03-2018 A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 Gene3D G3DSA:3.30.190.20 149 228 1.9E-19 T 28-03-2018 A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.5E-106 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.696 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 Gene3D G3DSA:3.40.50.790 68 148 2.5E-38 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.0E-57 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 PIRSF PIRSF002155 1 227 3.3E-80 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 SUPERFAMILY SSF56808 6 226 3.14E-86 T 28-03-2018 IPR023674 Ribosomal protein L1-like A21D_RS06435 9ec10d1b46fb540bd2ef29fbfc48742e 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 8.8E-107 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 235 46.947 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 Pfam PF01048 Phosphorylase superfamily 16 230 1.7E-39 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 SUPERFAMILY SSF53167 2 234 4.45E-90 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS13975 ecd81678d1e13d45e6d258dd94df93ab 235 Gene3D G3DSA:3.40.50.1580 8 235 4.0E-56 T 28-03-2018 A21D_RS02135 3204722bcfb2c75e0868cb811b917f26 362 Gene3D G3DSA:3.20.20.190 23 285 1.5E-81 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS02135 3204722bcfb2c75e0868cb811b917f26 362 SUPERFAMILY SSF51695 32 273 9.94E-80 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS02135 3204722bcfb2c75e0868cb811b917f26 362 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 38 271 1.9E-51 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS07800 47b6bf68d2df1768a2d9941102ec92e5 243 Pfam PF12730 ABC-2 family transporter protein 4 171 9.9E-17 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 423 8.5E-45 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Gene3D G3DSA:1.10.3120.10 213 401 6.7E-54 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 238 6.0E-15 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 SUPERFAMILY SSF102735 1 132 2.09E-40 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 PIRSF PIRSF003095 1 428 9.1E-141 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 SUPERFAMILY SSF54534 88 243 3.54E-38 T 28-03-2018 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 SUPERFAMILY SSF109998 250 426 7.32E-43 T 28-03-2018 IPR027304 Trigger factor/SurA domain A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Gene3D G3DSA:3.30.70.1050 1 119 6.3E-40 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 1.7E-45 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 Hamap MF_00303 Trigger factor [tig]. 1 428 24.369 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A21D_RS15080 290310adfc6c9439ccdfa6bc45e656b2 428 TIGRFAM TIGR00115 tig: trigger factor 12 422 6.3E-144 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A21D_RS08225 72dd928bceda0b6a99a2c0410aa2be2c 199 PIRSF PIRSF020680 1 199 3.1E-41 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 A21D_RS08225 72dd928bceda0b6a99a2c0410aa2be2c 199 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 3 191 1.1E-39 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 A21D_RS08225 72dd928bceda0b6a99a2c0410aa2be2c 199 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 4 193 1.5E-41 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 A21D_RS08225 72dd928bceda0b6a99a2c0410aa2be2c 199 SUPERFAMILY SSF159709 7 194 2.09E-31 T 28-03-2018 A21D_RS10035 6d9aabdf09da875381f70b95ea47577a 118 SUPERFAMILY SSF52091 3 109 3.73E-19 T 28-03-2018 IPR002645 STAS domain A21D_RS10035 6d9aabdf09da875381f70b95ea47577a 118 Pfam PF01740 STAS domain 10 98 5.2E-12 T 28-03-2018 IPR002645 STAS domain A21D_RS10035 6d9aabdf09da875381f70b95ea47577a 118 Gene3D G3DSA:3.30.750.24 1 117 3.0E-14 T 28-03-2018 IPR002645 STAS domain A21D_RS15770 c31c9658292624f115b213932d8cd77a 125 Gene3D G3DSA:1.10.760.10 30 125 2.2E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS15770 c31c9658292624f115b213932d8cd77a 125 PIRSF PIRSF000025 1 125 2.7E-38 T 28-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A21D_RS15770 c31c9658292624f115b213932d8cd77a 125 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 121 3.8E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS15770 c31c9658292624f115b213932d8cd77a 125 SUPERFAMILY SSF46626 47 123 5.87E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 10 424 41.986 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 Gene3D G3DSA:3.40.50.1980 24 222 7.7E-88 T 28-03-2018 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PIRSF PIRSF000099 1 427 1.4E-171 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 31 423 1.9E-167 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 SUPERFAMILY SSF53720 26 424 5.3E-87 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 226 258 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 Pfam PF00815 Histidinol dehydrogenase 22 423 2.2E-170 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 226 247 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 132 158 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 31 55 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 PRINTS PR00083 Histidinol dehydrogenase signature 248 267 4.3E-89 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A21D_RS03030 e89cd9a3c6a2fa873e9ca60ef60d651b 431 Gene3D G3DSA:3.40.50.1980 223 368 2.8E-68 T 28-03-2018 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 1 530 8.4E-253 T 28-03-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 SUPERFAMILY SSF55604 457 531 3.4E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 Pfam PF02378 Phosphotransferase system, EIIC 9 344 1.0E-67 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 Pfam PF00367 phosphotransferase system, EIIB 461 490 3.6E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 407 517 1.8E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 469 486 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS07095 17942fb5043c20559908d4f6ea79f467 535 Gene3D G3DSA:3.30.1360.60 452 527 1.8E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 PRINTS PR00834 HtrA/DegQ protease family signature 123 135 1.1E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 PRINTS PR00834 HtrA/DegQ protease family signature 184 208 1.1E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 PRINTS PR00834 HtrA/DegQ protease family signature 144 164 1.1E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 1.1E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 PRINTS PR00834 HtrA/DegQ protease family signature 238 255 1.1E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 Gene3D G3DSA:2.40.10.10 180 272 1.4E-17 T 28-03-2018 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 Gene3D G3DSA:2.40.10.10 88 179 5.1E-21 T 28-03-2018 A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 SUPERFAMILY SSF50494 92 270 2.02E-40 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS12880 db9214496a6945a79d3e622b3106c2ea 273 Pfam PF13365 Trypsin-like peptidase domain 114 245 1.1E-25 T 28-03-2018 A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 Gene3D G3DSA:1.10.1660.10 1 137 2.0E-40 T 28-03-2018 A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 SMART SM00422 1 70 1.8E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 Pfam PF07739 TipAS antibiotic-recognition domain 128 238 4.7E-30 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 Gene3D G3DSA:1.10.490.50 155 242 1.3E-27 T 28-03-2018 A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 SUPERFAMILY SSF46955 2 113 2.49E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 Pfam PF13411 MerR HTH family regulatory protein 3 68 9.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS03590 821ee72f7f6d4bab389452dd0025e163 242 SUPERFAMILY SSF89082 156 240 8.11E-26 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF47336 1540 1610 2.49E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 486 7.2E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 ProSitePatterns PS00012 Phosphopantetheine attachment site. 543 558 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:2.30.38.10 1350 1426 1.6E-21 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.40.50.980 7 150 1.6E-27 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:1.10.1200.10 514 590 9.6E-6 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF56801 1000 1559 1.31E-132 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.40.50.980 151 316 9.1E-30 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Pfam PF00668 Condensation domain 608 1016 1.3E-49 T 28-03-2018 IPR001242 Condensation domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.30.300.30 397 506 2.7E-22 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1065 1458 2.6E-110 T 28-03-2018 IPR010071 Amino acid adenylation domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1570 1585 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF47336 519 620 2.22E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF52777 611 789 1.33E-25 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:2.30.38.10 317 396 4.1E-16 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1183 1194 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF56801 16 502 3.4E-99 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.40.50.980 1189 1349 1.8E-33 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.30.559.10 591 788 1.2E-18 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 SUPERFAMILY SSF52777 785 1017 9.67E-30 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.40.50.980 1035 1188 3.6E-39 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Pfam PF00550 Phosphopantetheine attachment site 1549 1608 4.6E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Pfam PF00501 AMP-binding enzyme 1044 1433 2.7E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Pfam PF00501 AMP-binding enzyme 13 403 2.5E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:1.10.1200.10 1552 1611 3.7E-18 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 Gene3D G3DSA:3.30.300.30 1429 1551 2.7E-24 T 28-03-2018 A21D_RS11925 333a91f8a36d1f59135f2299c898251f 1611 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 Gene3D G3DSA:3.40.50.720 11 197 5.7E-69 T 28-03-2018 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 152 165 2.7E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 176 204 2.7E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 228 245 2.7E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 333 359 2.7E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 246 262 2.7E-45 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 186 192 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 Gene3D G3DSA:3.30.360.10 198 493 4.3E-115 T 28-03-2018 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 17 196 2.1E-62 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 13 492 83.351 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 13 491 3.5E-192 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 SUPERFAMILY SSF55347 191 491 5.89E-112 T 28-03-2018 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 199 490 1.8E-108 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 PIRSF PIRSF000110 3 494 1.4E-181 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A21D_RS04410 861a9e62ce31f88007f1d6f1b5933e26 495 SUPERFAMILY SSF51735 11 199 4.13E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 187 272 1.3E-29 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 SUPERFAMILY SSF64518 1 273 4.18E-96 T 28-03-2018 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 3.2E-45 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 PRINTS PR00207 Flagellin signature 35 52 1.5E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 PRINTS PR00207 Flagellin signature 109 132 1.5E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 PRINTS PR00207 Flagellin signature 74 93 1.5E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A21D_RS11085 079825ebb3f2cadf79c7ee450b159aaa 273 Gene3D G3DSA:1.20.1330.10 38 245 4.2E-83 T 28-03-2018 A21D_RS05010 6121b24de2eaa39e1df410d81f5ca3d3 131 Pfam PF00583 Acetyltransferase (GNAT) family 9 98 2.7E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS05010 6121b24de2eaa39e1df410d81f5ca3d3 131 Gene3D G3DSA:3.40.630.30 1 130 2.5E-22 T 28-03-2018 A21D_RS05010 6121b24de2eaa39e1df410d81f5ca3d3 131 PIRSF PIRSF037663 1 131 2.4E-61 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted A21D_RS05010 6121b24de2eaa39e1df410d81f5ca3d3 131 SUPERFAMILY SSF55729 9 130 1.14E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 173 1.0E-50 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 SUPERFAMILY SSF52518 365 537 9.11E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Gene3D G3DSA:3.40.50.970 345 541 1.5E-44 T 28-03-2018 A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 SUPERFAMILY SSF52518 3 187 1.18E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Gene3D G3DSA:3.40.50.1220 199 344 1.6E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 1.2E-44 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 9.7E-37 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 SUPERFAMILY SSF52467 158 347 3.11E-44 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 Gene3D G3DSA:3.40.50.970 1 198 2.4E-49 T 28-03-2018 A21D_RS11485 057fbd177cf152ea0d441d4fb55742ec 550 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 SUPERFAMILY SSF51556 50 370 5.9E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 Gene3D G3DSA:3.20.20.140 63 358 2.4E-44 T 28-03-2018 A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 Gene3D G3DSA:2.30.40.10 1 62 1.2E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 Pfam PF07969 Amidohydrolase family 39 399 1.0E-51 T 28-03-2018 IPR013108 Amidohydrolase 3 A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 SUPERFAMILY SSF51338 2 49 5.67E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12010 ab5fc09afe108abcfa008c9873ad5623 422 SUPERFAMILY SSF51338 361 402 5.67E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04855 51648327c28696b99e83021dd99ebe1e 548 Gene3D G3DSA:3.30.200.20 101 243 6.0E-18 T 28-03-2018 A21D_RS04855 51648327c28696b99e83021dd99ebe1e 548 Gene3D G3DSA:3.90.1200.10 273 436 1.0E-6 T 28-03-2018 A21D_RS04855 51648327c28696b99e83021dd99ebe1e 548 SUPERFAMILY SSF56112 200 340 1.25E-22 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS04855 51648327c28696b99e83021dd99ebe1e 548 SUPERFAMILY SSF56112 94 157 1.25E-22 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS04855 51648327c28696b99e83021dd99ebe1e 548 Pfam PF03109 ABC1 family 111 227 1.0E-21 T 28-03-2018 IPR004147 UbiB domain A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Gene3D G3DSA:3.40.50.620 4 222 2.3E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Gene3D G3DSA:3.10.290.10 325 418 1.5E-22 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 SUPERFAMILY SSF55174 320 416 2.88E-23 T 28-03-2018 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 SUPERFAMILY SSF52374 1 322 4.29E-109 T 28-03-2018 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Gene3D G3DSA:1.10.240.10 223 324 9.5E-38 T 28-03-2018 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Pfam PF01479 S4 domain 354 394 2.3E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 416 2.0E-130 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 417 44.797 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 159 174 2.0E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 2.0E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 2.0E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 180 202 2.0E-28 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 322 5.1E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS11140 6b2dbd7a9dbad085403cd55ed1604035 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.373 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 Gene3D G3DSA:1.20.58.110 1 87 3.3E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 SUPERFAMILY SSF46992 3 86 8.63E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 8.0E-17 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15600 baefd577d27a3b48e99304c6f51b5fa0 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 5.7E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS09425 5a6316401b4fd2931cf421cec8955038 248 Pfam PF01569 PAP2 superfamily 97 208 4.0E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS09425 5a6316401b4fd2931cf421cec8955038 248 Gene3D G3DSA:1.20.144.10 34 212 6.0E-25 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS09425 5a6316401b4fd2931cf421cec8955038 248 SMART SM00014 90 204 1.5E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS09425 5a6316401b4fd2931cf421cec8955038 248 SUPERFAMILY SSF48317 8 210 7.06E-35 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A21D_RS10850 5350cd1e71d4cc0d590b6ba8f455ac51 319 Gene3D G3DSA:3.40.50.300 12 188 5.0E-25 T 28-03-2018 A21D_RS10850 5350cd1e71d4cc0d590b6ba8f455ac51 319 SUPERFAMILY SSF52540 10 285 3.55E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10850 5350cd1e71d4cc0d590b6ba8f455ac51 319 Gene3D G3DSA:1.10.8.300 202 310 3.2E-35 T 28-03-2018 A21D_RS10850 5350cd1e71d4cc0d590b6ba8f455ac51 319 PIRSF PIRSF002849 1 315 4.9E-134 T 28-03-2018 A21D_RS10850 5350cd1e71d4cc0d590b6ba8f455ac51 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 1.9E-65 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A21D_RS08410 25f368519a8d0fb015cf70944b1efcc9 172 Pfam PF03061 Thioesterase superfamily 26 100 2.3E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS08410 25f368519a8d0fb015cf70944b1efcc9 172 SUPERFAMILY SSF54637 4 154 8.46E-42 T 28-03-2018 IPR029069 HotDog domain A21D_RS08410 25f368519a8d0fb015cf70944b1efcc9 172 Gene3D G3DSA:3.10.129.10 1 161 5.2E-45 T 28-03-2018 A21D_RS08455 4fc7f5b75608cd4384f5cf6a8a969516 162 SUPERFAMILY SSF51261 3 148 2.96E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS08455 4fc7f5b75608cd4384f5cf6a8a969516 162 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 76 88 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS08455 4fc7f5b75608cd4384f5cf6a8a969516 162 Gene3D G3DSA:2.70.70.10 1 162 1.3E-58 T 28-03-2018 A21D_RS08455 4fc7f5b75608cd4384f5cf6a8a969516 162 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 14 134 7.8E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS08455 4fc7f5b75608cd4384f5cf6a8a969516 162 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 13 136 5.8E-51 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 47.209 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Pfam PF01926 50S ribosome-binding GTPase 5 121 1.9E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 1.0E-41 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Gene3D G3DSA:3.10.20.30 266 365 7.5E-49 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 6.5E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 6.5E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.5E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 6.5E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Gene3D G3DSA:3.40.50.300 1 80 2.1E-7 T 28-03-2018 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 Gene3D G3DSA:1.10.150.300 110 200 6.2E-30 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 SUPERFAMILY SSF52540 3 304 5.11E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 7.9E-162 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 SUPERFAMILY SSF81271 282 363 2.4E-37 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A21D_RS07320 6f3923e7c1c35749b1506c872a7f1f86 366 PIRSF PIRSF006641 1 366 6.9E-168 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A21D_RS04035 5f2c77a8a43f66f12a6ecb42cbeb8dd3 145 Gene3D G3DSA:3.40.630.30 1 145 1.9E-27 T 28-03-2018 A21D_RS04035 5f2c77a8a43f66f12a6ecb42cbeb8dd3 145 Pfam PF13673 Acetyltransferase (GNAT) domain 24 143 7.1E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS04035 5f2c77a8a43f66f12a6ecb42cbeb8dd3 145 SUPERFAMILY SSF55729 7 143 3.66E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS16340 099260b1d086e6db411c234ab78eab00 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 1.1E-33 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A21D_RS16340 099260b1d086e6db411c234ab78eab00 117 Gene3D G3DSA:3.30.750.24 5 115 8.7E-24 T 28-03-2018 IPR002645 STAS domain A21D_RS16340 099260b1d086e6db411c234ab78eab00 117 Pfam PF01740 STAS domain 9 106 2.0E-22 T 28-03-2018 IPR002645 STAS domain A21D_RS16340 099260b1d086e6db411c234ab78eab00 117 SUPERFAMILY SSF52091 6 111 2.62E-28 T 28-03-2018 IPR002645 STAS domain A21D_RS16340 099260b1d086e6db411c234ab78eab00 117 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 7 110 5.8E-45 T 28-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 297 2.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 SUPERFAMILY SSF47384 217 297 8.24E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 Gene3D G3DSA:3.30.565.10 304 450 2.7E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 SUPERFAMILY SSF55874 290 449 2.36E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 Gene3D G3DSA:1.10.287.130 223 296 3.7E-15 T 28-03-2018 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 8.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 8.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 8.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 8.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 SMART SM00388 233 300 2.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 SMART SM00387 341 450 2.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09885 286b96c6eaf4dfcbb4eb0b1e028f5bbf 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 448 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS13800 94849156e3731179a16c183c62452a2b 410 Pfam PF16325 Peptidase family U32 C-terminal domain 327 407 6.0E-27 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal A21D_RS13800 94849156e3731179a16c183c62452a2b 410 Pfam PF01136 Peptidase family U32 80 312 1.4E-85 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A21D_RS13800 94849156e3731179a16c183c62452a2b 410 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A21D_RS13800 94849156e3731179a16c183c62452a2b 410 Gene3D G3DSA:3.20.20.70 3 190 8.2E-6 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03145 47a95a727b17f0bceae22b77664ffeaa 222 Pfam PF00005 ABC transporter 19 166 4.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03145 47a95a727b17f0bceae22b77664ffeaa 222 SMART SM00382 28 214 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03145 47a95a727b17f0bceae22b77664ffeaa 222 Gene3D G3DSA:3.40.50.300 1 222 6.5E-61 T 28-03-2018 A21D_RS03145 47a95a727b17f0bceae22b77664ffeaa 222 SUPERFAMILY SSF52540 2 216 7.1E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03145 47a95a727b17f0bceae22b77664ffeaa 222 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 SUPERFAMILY SSF56176 5 217 2.76E-73 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 SUPERFAMILY SSF55103 220 460 2.78E-69 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 Pfam PF01565 FAD binding domain 41 179 5.6E-41 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 Gene3D G3DSA:3.30.465.10 93 239 7.8E-42 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 Gene3D G3DSA:3.30.43.10 1 92 8.0E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 456 1.0E-73 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 Gene3D G3DSA:1.10.45.10 418 457 1.1E-15 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A21D_RS11320 bdb16f4ddf55eee6e8baf7da4b0fbb3e 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 45 456 1.2E-173 T 28-03-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 Gene3D G3DSA:1.20.5.110 63 98 7.0E-9 T 28-03-2018 A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 Gene3D G3DSA:1.10.287.70 15 61 1.8E-7 T 28-03-2018 A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 SUPERFAMILY SSF51735 115 258 8.66E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 Pfam PF07885 Ion channel 24 97 2.9E-16 T 28-03-2018 IPR013099 Potassium channel domain A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 Gene3D G3DSA:3.40.50.720 106 244 5.8E-14 T 28-03-2018 A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 Pfam PF02254 TrkA-N domain 132 243 9.8E-6 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A21D_RS09185 de074cb8fbd5794b76f8b633179d6060 346 SUPERFAMILY SSF81324 14 133 1.28E-24 T 28-03-2018 A21D_RS17695 e9b1ca989f7cd0f033345b9ad1cc3aaf 315 Pfam PF01522 Polysaccharide deacetylase 128 245 1.5E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS17695 e9b1ca989f7cd0f033345b9ad1cc3aaf 315 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 44 311 6.4E-130 T 28-03-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY A21D_RS17695 e9b1ca989f7cd0f033345b9ad1cc3aaf 315 SUPERFAMILY SSF88713 108 311 2.45E-54 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS17695 e9b1ca989f7cd0f033345b9ad1cc3aaf 315 Gene3D G3DSA:3.20.20.370 85 315 1.7E-47 T 28-03-2018 A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 SUPERFAMILY SSF56784 3 270 8.27E-68 T 28-03-2018 IPR023214 HAD-like domain A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 ProSitePatterns PS01228 Hypothetical cof family signature 1. 7 18 - T 28-03-2018 A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 239 1.8E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 266 1.4E-70 T 28-03-2018 IPR023214 HAD-like domain A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 266 6.3E-60 T 28-03-2018 IPR000150 Cof family GO:0016787 A21D_RS13375 643b5cc696b5a7a22c62ca7935c35300 273 Gene3D G3DSA:3.40.50.1000 1 272 1.8E-40 T 28-03-2018 IPR023214 HAD-like domain A21D_RS15095 be5dca2020f167d68b4f18c0d38031d7 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 29.474 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A21D_RS15095 be5dca2020f167d68b4f18c0d38031d7 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 7.4E-73 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A21D_RS15095 be5dca2020f167d68b4f18c0d38031d7 195 SUPERFAMILY SSF52540 17 193 2.07E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15095 be5dca2020f167d68b4f18c0d38031d7 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 1.5E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15095 be5dca2020f167d68b4f18c0d38031d7 195 Gene3D G3DSA:3.40.50.300 3 195 4.7E-31 T 28-03-2018 A21D_RS02675 230389692777063843098e91cd7552ea 233 Pfam PF13614 AAA domain 60 210 6.8E-15 T 28-03-2018 IPR025669 AAA domain A21D_RS02675 230389692777063843098e91cd7552ea 233 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 29 231 3.3E-72 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A21D_RS02675 230389692777063843098e91cd7552ea 233 Gene3D G3DSA:3.40.50.300 15 227 2.1E-37 T 28-03-2018 A21D_RS02675 230389692777063843098e91cd7552ea 233 SUPERFAMILY SSF52540 49 225 2.74E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 Gene3D G3DSA:2.170.120.20 99 187 2.5E-28 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 3 92 2.0E-32 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 SUPERFAMILY SSF50715 10 182 1.92E-53 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 Pfam PF01386 Ribosomal L25p family 5 92 5.2E-23 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 180 6.2E-53 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 181 26.73 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 182 7.4E-27 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain A21D_RS06750 0e4c43c771cee97f27e0051de64515a0 207 Gene3D G3DSA:2.40.240.10 2 94 5.9E-27 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A21D_RS16080 c5049241481c40baeed9f84d5731891d 215 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 24 215 1.1E-61 T 28-03-2018 IPR014195 Sporulation stage III, protein AG A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Pfam PF13426 PAS domain 47 144 9.9E-10 T 28-03-2018 IPR000014 PAS domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Gene3D G3DSA:3.30.450.20 41 136 1.1E-14 T 28-03-2018 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SUPERFAMILY SSF47384 159 221 1.1E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Gene3D G3DSA:3.30.565.10 226 372 1.0E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SMART SM00091 36 102 4.5E-9 T 28-03-2018 IPR000014 PAS domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SUPERFAMILY SSF55785 39 144 2.88E-13 T 28-03-2018 IPR000014 PAS domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SMART SM00387 266 372 3.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Pfam PF00512 His Kinase A (phospho-acceptor) domain 165 221 3.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 350 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 317 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 369 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 331 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SUPERFAMILY SSF55874 215 370 3.93E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 369 6.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 36 153 8.3E-16 T 28-03-2018 IPR000014 PAS domain A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 SMART SM00388 163 225 3.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS17120 ad9ef6f57f641895467abc6713433224 372 Gene3D G3DSA:1.10.287.130 137 221 5.9E-14 T 28-03-2018 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 8.9E-71 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 SUPERFAMILY SSF51412 3 314 3.27E-93 T 28-03-2018 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 PIRSF PIRSF036500 1 326 2.4E-197 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 4.5E-202 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 Gene3D G3DSA:3.20.20.70 1 327 6.7E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 SMART SM01240 3 327 1.4E-118 T 28-03-2018 A21D_RS07565 1e98842a0a54b2c44fe8f0ab84706e5b 328 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.928 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 A21D_RS03530 29870e744009287dbd431a238925981d 152 Gene3D G3DSA:3.40.50.620 18 151 2.9E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS03530 29870e744009287dbd431a238925981d 152 SUPERFAMILY SSF52402 27 141 4.83E-22 T 28-03-2018 A21D_RS03530 29870e744009287dbd431a238925981d 152 Pfam PF06508 Queuosine biosynthesis protein QueC 29 133 2.1E-24 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A21D_RS11350 f4e73229be797b21a8149f4b3c930944 99 Pfam PF00581 Rhodanese-like domain 7 95 1.5E-11 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11350 f4e73229be797b21a8149f4b3c930944 99 SUPERFAMILY SSF52821 2 95 4.19E-27 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11350 f4e73229be797b21a8149f4b3c930944 99 Gene3D G3DSA:3.40.250.10 1 98 2.5E-24 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11350 f4e73229be797b21a8149f4b3c930944 99 SMART SM00450 5 99 1.8E-13 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.722 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 Gene3D G3DSA:3.40.50.300 7 141 2.5E-46 T 28-03-2018 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 SUPERFAMILY SSF57716 142 195 8.55E-17 T 28-03-2018 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 Pfam PF00265 Thymidine kinase 8 187 1.4E-58 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 SUPERFAMILY SSF52540 8 142 1.39E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 Gene3D G3DSA:3.30.60.20 142 199 4.1E-19 T 28-03-2018 A21D_RS04660 da8329d2599d7239177a4dd0f2589058 207 PIRSF PIRSF035805 5 200 1.4E-64 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A21D_RS03965 6788c03e50849f95ed696be4af42067f 450 Pfam PF02386 Cation transport protein 45 438 2.4E-57 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A21D_RS03965 6788c03e50849f95ed696be4af42067f 450 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 37 422 1.0E-114 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 SMART SM00421 146 203 2.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 Gene3D G3DSA:1.10.10.10 122 210 5.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 SUPERFAMILY SSF46894 144 207 1.22E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 6.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 Pfam PF00072 Response regulator receiver domain 4 116 7.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 Gene3D G3DSA:3.40.50.2300 1 121 6.2E-30 T 28-03-2018 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 SMART SM00448 2 116 4.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS02865 82fb46cf17668267cdc8cb02c17a7248 211 SUPERFAMILY SSF52172 1 126 1.21E-31 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS12640 245cdf9b041d8df0530293778557db15 346 Gene3D G3DSA:3.90.226.10 1 339 1.2E-73 T 28-03-2018 A21D_RS12640 245cdf9b041d8df0530293778557db15 346 Pfam PF16113 Enoyl-CoA hydratase/isomerase 14 345 9.2E-116 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 A21D_RS12640 245cdf9b041d8df0530293778557db15 346 SUPERFAMILY SSF52096 2 196 1.49E-56 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS12640 245cdf9b041d8df0530293778557db15 346 SUPERFAMILY SSF52096 259 325 1.49E-56 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 Pfam PF06144 DNA polymerase III, delta subunit 19 192 3.2E-42 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 Gene3D G3DSA:1.10.8.60 146 224 2.5E-15 T 28-03-2018 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 Gene3D G3DSA:3.40.50.300 1 143 1.5E-26 T 28-03-2018 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 Gene3D G3DSA:1.20.272.10 225 341 7.9E-29 T 28-03-2018 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 335 1.3E-78 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 SUPERFAMILY SSF48019 218 335 4.76E-22 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A21D_RS15595 6c24da69b3dc13c544eaf75df605c13f 341 SUPERFAMILY SSF52540 4 213 1.99E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14255 264fbaeb14d8b33256f8383305d67995 270 Pfam PF01636 Phosphotransferase enzyme family 18 229 6.7E-26 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase A21D_RS14255 264fbaeb14d8b33256f8383305d67995 270 SUPERFAMILY SSF56112 2 237 9.85E-33 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS14255 264fbaeb14d8b33256f8383305d67995 270 Gene3D G3DSA:3.90.1200.10 32 265 1.2E-22 T 28-03-2018 A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 Gene3D G3DSA:3.40.1280.10 75 248 2.8E-48 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 243 2.8E-83 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 SUPERFAMILY SSF55315 3 76 5.41E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 SUPERFAMILY SSF75217 68 244 4.64E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 Gene3D G3DSA:3.30.1330.30 1 74 9.8E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 Pfam PF00588 SpoU rRNA Methylase family 97 237 2.2E-39 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 SMART SM00967 5 80 2.3E-18 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A21D_RS06470 3b53e796ef1b1e59588463b29bc7c22e 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 6.2E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 SUPERFAMILY SSF52172 1 183 1.34E-38 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 SMART SM00862 149 223 8.0E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 Gene3D G3DSA:1.10.10.10 124 224 2.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 Pfam PF00072 Response regulator receiver domain 6 114 2.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 SMART SM00448 4 114 1.0E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 223 1.3E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS00425 e09319dcce50c551c46fac0226a26bbb 224 Gene3D G3DSA:3.40.50.2300 1 123 1.2E-33 T 28-03-2018 A21D_RS19320 c31aaf40d02b7b313e3ce5fde194f950 150 Gene3D G3DSA:3.30.530.20 4 146 1.0E-14 T 28-03-2018 IPR023393 START-like domain A21D_RS19320 c31aaf40d02b7b313e3ce5fde194f950 150 SUPERFAMILY SSF55961 6 143 6.68E-25 T 28-03-2018 A21D_RS19320 c31aaf40d02b7b313e3ce5fde194f950 150 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 8 143 8.7E-10 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Gene3D G3DSA:3.40.50.410 258 497 7.3E-32 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 SMART SM00327 264 491 1.0E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Pfam PF00746 LPXTG cell wall anchor motif 864 897 6.0E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Gene3D G3DSA:2.60.40.10 780 864 3.5E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Gene3D G3DSA:2.60.40.1220 498 587 8.6E-7 T 28-03-2018 A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 SUPERFAMILY SSF53300 255 378 5.69E-25 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 SUPERFAMILY SSF53300 432 490 5.69E-25 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Gene3D G3DSA:3.10.20.320 697 779 1.2E-19 T 28-03-2018 A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Pfam PF06458 MucBP domain 704 768 4.6E-17 T 28-03-2018 IPR009459 MucBP domain A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 864 896 9.1E-6 T 28-03-2018 A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 SUPERFAMILY SSF49478 779 843 2.04E-9 T 28-03-2018 A21D_RS01760 7b05488d9b4b858cc44cdc6c5a02de14 911 Pfam PF00092 von Willebrand factor type A domain 266 379 5.0E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS18645 633609a48e98ddfbbc4cba94629f083e 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS18645 633609a48e98ddfbbc4cba94629f083e 536 Pfam PF13751 Transposase DDE domain 393 518 1.7E-31 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS18645 633609a48e98ddfbbc4cba94629f083e 536 Gene3D G3DSA:3.90.350.10 230 497 2.7E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS18450 baccc22f5d4eec382dc338121989d452 160 SUPERFAMILY SSF46689 7 65 8.16E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS18450 baccc22f5d4eec382dc338121989d452 160 Gene3D G3DSA:1.10.10.60 2 133 6.6E-8 T 28-03-2018 A21D_RS18450 baccc22f5d4eec382dc338121989d452 160 Pfam PF13921 Myb-like DNA-binding domain 9 64 3.3E-6 T 28-03-2018 A21D_RS18450 baccc22f5d4eec382dc338121989d452 160 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 135 4.6E-42 T 28-03-2018 IPR014243 Transcription factor, RsfA A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Gene3D G3DSA:3.40.50.980 2 159 3.0E-27 T 28-03-2018 A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Gene3D G3DSA:3.30.300.30 388 493 5.5E-24 T 28-03-2018 A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Pfam PF00501 AMP-binding enzyme 11 394 1.6E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Gene3D G3DSA:2.30.38.10 308 387 6.1E-22 T 28-03-2018 A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Gene3D G3DSA:3.40.50.980 160 307 4.4E-25 T 28-03-2018 A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 404 478 2.3E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS02310 9cfebde6095107cc67b37ccef10006b9 493 SUPERFAMILY SSF56801 3 491 1.7E-110 T 28-03-2018 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 SUPERFAMILY SSF48498 86 195 8.9E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 Gene3D G3DSA:1.10.10.60 2 60 2.0E-16 T 28-03-2018 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 SUPERFAMILY SSF46689 2 72 8.48E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 Pfam PF08359 YsiA-like protein, C-terminal region 78 185 2.2E-6 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 Gene3D G3DSA:1.10.357.10 65 197 7.2E-12 T 28-03-2018 A21D_RS12155 43a329d3200a78e870086091a94dd72a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 4.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS19235 b98498c339b701a2582154da800840e1 274 PIRSF PIRSF034452 1 274 1.4E-142 T 28-03-2018 IPR009215 TIM-barrel domain, IGPS-like A21D_RS19235 b98498c339b701a2582154da800840e1 274 SUPERFAMILY SSF51621 2 195 2.42E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS19235 b98498c339b701a2582154da800840e1 274 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 6 272 1.3E-130 T 28-03-2018 IPR009215 TIM-barrel domain, IGPS-like A21D_RS19235 b98498c339b701a2582154da800840e1 274 Gene3D G3DSA:3.20.20.70 2 250 3.0E-126 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS19235 b98498c339b701a2582154da800840e1 274 Gene3D G3DSA:1.20.5.460 251 272 1.5E-9 T 28-03-2018 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 Gene3D G3DSA:3.30.70.260 15 106 3.7E-23 T 28-03-2018 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 Pfam PF00551 Formyl transferase 104 281 3.8E-42 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 9.9E-128 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 SUPERFAMILY SSF53328 105 299 5.36E-58 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 Pfam PF01842 ACT domain 21 67 2.3E-6 T 28-03-2018 IPR002912 ACT domain A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 45.576 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 8.5E-58 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 SUPERFAMILY SSF55021 19 101 2.78E-17 T 28-03-2018 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 Gene3D G3DSA:3.40.50.170 107 297 3.7E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A21D_RS01150 e61e0960c17cd20ea5f431003c90d374 299 PIRSF PIRSF036480 17 299 2.9E-111 T 28-03-2018 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Gene3D G3DSA:3.30.70.1450 274 351 3.7E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 SUPERFAMILY SSF116726 268 345 5.89E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Pfam PF06826 Predicted Permease Membrane Region 360 528 2.6E-37 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Pfam PF06826 Predicted Permease Membrane Region 16 168 6.5E-35 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Pfam PF02080 TrkA-C domain 195 257 6.2E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Pfam PF02080 TrkA-C domain 280 345 2.7E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 SUPERFAMILY SSF116726 193 263 3.27E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 155 2.9E-22 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 365 516 3.6E-35 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12355 0de3d619a52a234964405e95dc05167d 532 Gene3D G3DSA:3.30.70.1450 188 268 1.8E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS09305 c8a6d86cc70f691f3fe9c4e751483e44 118 Pfam PF10941 Protein of unknown function DUF2620 1 115 1.2E-48 T 28-03-2018 IPR021238 Protein of unknown function DUF2620 A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 132 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 212 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 4.4E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 7.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 132 7.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 193 212 7.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 Gene3D G3DSA:3.40.50.720 1 287 8.8E-75 T 28-03-2018 A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 180 208 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 283 4.5E-62 T 28-03-2018 A21D_RS07505 d099da5a0228502b7e9aa776d2b759e0 288 SUPERFAMILY SSF51735 44 285 2.25E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 Pfam PF00271 Helicase conserved C-terminal domain 220 327 3.0E-19 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 SMART SM00490 246 328 2.5E-25 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 SMART SM00487 17 214 4.3E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 Pfam PF00270 DEAD/DEAH box helicase 24 183 2.0E-24 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 135 144 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 SUPERFAMILY SSF52540 60 349 1.28E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 Gene3D G3DSA:3.40.50.300 3 216 3.1E-36 T 28-03-2018 A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 Gene3D G3DSA:3.40.50.300 217 480 5.8E-42 T 28-03-2018 A21D_RS16470 4a2a4b7348e29a4008d0603520f84430 517 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 12 352 2.3E-102 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 227 242 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 Pfam PF00248 Aldo/keto reductase family 15 258 1.8E-56 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PIRSF PIRSF000097 1 272 3.6E-97 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 Gene3D G3DSA:3.20.20.100 1 274 2.0E-105 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PRINTS PR00069 Aldo-keto reductase signature 34 58 5.5E-51 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PRINTS PR00069 Aldo-keto reductase signature 156 185 5.5E-51 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PRINTS PR00069 Aldo-keto reductase signature 90 108 5.5E-51 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PRINTS PR00069 Aldo-keto reductase signature 122 139 5.5E-51 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 PRINTS PR00069 Aldo-keto reductase signature 194 218 5.5E-51 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 SUPERFAMILY SSF51430 3 263 3.54E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS03115 daa881d0d1a28dd74a03ced852204142 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 1.1E-130 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Gene3D G3DSA:3.30.1480.10 1 129 3.3E-49 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 363 30.411 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SUPERFAMILY SSF50249 132 198 5.88E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Pfam PF08529 NusA N-terminal domain 5 123 8.9E-46 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Gene3D G3DSA:2.40.50.140 136 197 2.2E-13 T 28-03-2018 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SUPERFAMILY SSF54814 199 277 9.16E-31 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SMART SM00322 303 364 1.6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SMART SM00322 229 302 0.001 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Gene3D G3DSA:3.30.300.20 277 347 1.2E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Gene3D G3DSA:3.30.300.20 198 275 1.2E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SUPERFAMILY SSF69705 2 126 1.44E-43 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SUPERFAMILY SSF54814 278 341 1.05E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 SMART SM00316 133 199 2.9E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Pfam PF13184 NusA-like KH domain 229 296 8.2E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 A21D_RS17745 ed1eec0540320a4999efb5d754786bfb 365 Pfam PF00575 S1 RNA binding domain 132 196 1.4E-9 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 SUPERFAMILY SSF52833 3 103 4.21E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 2.8E-40 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 Gene3D G3DSA:3.40.30.10 1 104 1.4E-34 T 28-03-2018 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.2E-9 T 28-03-2018 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.2E-9 T 28-03-2018 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.2E-9 T 28-03-2018 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 Pfam PF00085 Thioredoxin 4 103 7.2E-32 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS14810 c86af12a499c2d6b231b1e8d07efac30 104 PIRSF PIRSF000077 1 104 1.2E-42 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A21D_RS17685 1e58189cc1a903b36aa65b032f43cf43 80 Gene3D G3DSA:2.30.30.240 1 79 2.6E-12 T 28-03-2018 A21D_RS17685 1e58189cc1a903b36aa65b032f43cf43 80 SUPERFAMILY SSF50346 2 75 8.63E-11 T 28-03-2018 IPR011033 PRC-barrel-like A21D_RS17685 1e58189cc1a903b36aa65b032f43cf43 80 Pfam PF05239 PRC-barrel domain 2 76 4.6E-12 T 28-03-2018 IPR027275 PRC-barrel domain A21D_RS17685 1e58189cc1a903b36aa65b032f43cf43 80 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 6.7E-30 T 28-03-2018 IPR014238 Sporulation protein YlmC/YmxH A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 SUPERFAMILY SSF52172 6 136 2.85E-33 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 Gene3D G3DSA:1.10.10.10 132 229 6.6E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 SMART SM00448 7 120 2.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 Pfam PF00072 Response regulator receiver domain 9 121 1.5E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 220 4.6E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 3.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 3.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 3.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 Gene3D G3DSA:3.40.50.2300 6 131 7.3E-33 T 28-03-2018 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 SMART SM00421 164 221 3.9E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 SUPERFAMILY SSF46894 156 227 3.1E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS00915 e9474684fe29cf98f59b1a8c97882e68 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 Gene3D G3DSA:1.10.287.1040 5 70 4.6E-25 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 48 7.0E-12 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 PIRSF PIRSF006488 1 76 2.0E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 15.551 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 63 8.8E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 Pfam PF02609 Exonuclease VII small subunit 8 59 8.1E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A21D_RS16120 fc3aa1b17abc0d1fbed537cef96cebc6 76 SUPERFAMILY SSF116842 2 67 5.89E-22 T 28-03-2018 A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 PRINTS PR00332 Histidine triad family signature 7 23 7.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 PRINTS PR00332 Histidine triad family signature 28 46 7.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 PRINTS PR00332 Histidine triad family signature 95 105 7.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 Gene3D G3DSA:3.30.428.10 1 123 1.0E-37 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 28-03-2018 IPR019808 Histidine triad, conserved site A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 SUPERFAMILY SSF54197 4 141 4.64E-43 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 Gene3D G3DSA:1.20.5.1170 124 141 4.6E-11 T 28-03-2018 A21D_RS13130 0af441fef3d9f6a0f01d9f9229458eee 142 Pfam PF01230 HIT domain 14 108 7.0E-25 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS08540 3ca0385f9e349eee57a34050ddd7d4af 322 Gene3D G3DSA:3.10.180.10 2 147 1.6E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS08540 3ca0385f9e349eee57a34050ddd7d4af 322 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 158 273 4.4E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS08540 3ca0385f9e349eee57a34050ddd7d4af 322 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 106 1.9E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS08540 3ca0385f9e349eee57a34050ddd7d4af 322 SUPERFAMILY SSF54593 3 301 4.28E-51 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS08540 3ca0385f9e349eee57a34050ddd7d4af 322 Gene3D G3DSA:3.10.180.10 150 318 7.3E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 SUPERFAMILY SSF52540 77 166 4.04E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 SUPERFAMILY SSF52540 201 375 4.04E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 SUPERFAMILY SSF116878 383 458 4.58E-49 T 28-03-2018 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 SUPERFAMILY SSF116878 124 224 4.58E-49 T 28-03-2018 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 458 5.2E-128 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Gene3D G3DSA:1.20.120.430 286 458 1.3E-29 T 28-03-2018 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Gene3D G3DSA:3.30.1360.120 1 124 3.7E-44 T 28-03-2018 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 123 2.2E-40 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 458 33.851 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Pfam PF12631 MnmE helical domain 126 455 4.5E-58 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 370 1.2E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Pfam PF01926 50S ribosome-binding GTPase 224 335 3.6E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS07255 732ec3b12f3d35f06caf5a1b63a42a51 458 Gene3D G3DSA:1.20.120.430 125 285 6.1E-31 T 28-03-2018 A21D_RS05805 b5ae6dd6a5717613faf4b644253f92bd 308 Gene3D G3DSA:3.40.50.1980 149 308 2.0E-25 T 28-03-2018 A21D_RS05805 b5ae6dd6a5717613faf4b644253f92bd 308 Gene3D G3DSA:3.40.50.1980 39 148 7.1E-21 T 28-03-2018 A21D_RS05805 b5ae6dd6a5717613faf4b644253f92bd 308 SUPERFAMILY SSF53807 41 301 1.02E-50 T 28-03-2018 A21D_RS05805 b5ae6dd6a5717613faf4b644253f92bd 308 Pfam PF01497 Periplasmic binding protein 64 281 1.4E-27 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS04695 7f2cfc27fe69293395c499113393aae5 119 SMART SM00448 3 114 8.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS04695 7f2cfc27fe69293395c499113393aae5 119 SUPERFAMILY SSF52172 3 119 5.83E-30 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS04695 7f2cfc27fe69293395c499113393aae5 119 Gene3D G3DSA:3.40.50.2300 1 119 6.6E-29 T 28-03-2018 A21D_RS04695 7f2cfc27fe69293395c499113393aae5 119 Pfam PF00072 Response regulator receiver domain 5 114 2.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 Pfam PF00355 Rieske [2Fe-2S] domain 9 88 4.7E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 SUPERFAMILY SSF55961 118 318 7.51E-27 T 28-03-2018 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 49 71 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 SUPERFAMILY SSF50022 6 125 1.44E-32 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 Gene3D G3DSA:2.102.10.10 7 111 3.7E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS12220 fe62a98a84344cc485366a3b573b03bb 335 Gene3D G3DSA:3.90.380.10 112 320 4.6E-37 T 28-03-2018 A21D_RS14860 6db891ff23f2d55fa240c0c8edc16af3 294 Pfam PF03773 Predicted permease 6 291 5.7E-62 T 28-03-2018 IPR005524 Predicted permease DUF318 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF00929 Exonuclease 415 569 2.8E-40 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 411 628 6.9E-59 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Gene3D G3DSA:1.20.5.140 563 582 5.0E-12 T 28-03-2018 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Gene3D G3DSA:1.10.150.280 1306 1416 7.9E-4 T 28-03-2018 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1428 432.295 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Gene3D G3DSA:2.40.50.140 212 313 2.3E-18 T 28-03-2018 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Gene3D G3DSA:3.30.420.10 405 562 2.5E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF01336 OB-fold nucleic acid binding domain 232 310 9.7E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF14480 DNA polymerase III polC-type N-terminus I 9 79 5.0E-18 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF14579 Helix-hairpin-helix motif 1344 1421 3.9E-10 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 SUPERFAMILY SSF53098 413 868 5.16E-106 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 815 1236 6.1E-97 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF11490 DNA polymerase III polC-type N-terminus II 93 197 5.9E-20 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Gene3D G3DSA:3.20.20.140 594 787 1.0E-20 T 28-03-2018 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 SUPERFAMILY SSF50249 228 301 8.91E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 223 1428 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 Pfam PF02811 PHP domain 329 687 4.4E-55 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 SUPERFAMILY SSF89550 339 410 2.2E-5 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 SMART SM00479 413 579 7.8E-52 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A21D_RS17755 da139ad29ec1437a072954df0d1d8fe5 1428 SMART SM00481 328 395 8.4E-29 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 Gene3D G3DSA:1.10.287.950 317 564 9.3E-58 T 28-03-2018 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 Gene3D G3DSA:1.10.287.950 136 316 7.3E-11 T 28-03-2018 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 SMART SM00283 288 563 4.7E-79 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 SUPERFAMILY SSF58104 294 563 4.84E-70 T 28-03-2018 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 SUPERFAMILY SSF58104 232 261 4.84E-70 T 28-03-2018 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 1.2E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 18 43 1.2E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 413 1.2E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 Pfam PF12729 Four helix bundle sensory module for signal transduction 9 91 1.5E-6 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 348 516 1.9E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 SMART SM00304 206 259 5.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS02380 7e536cd3cfb9ae59f38d916b15785159 564 Pfam PF00672 HAMP domain 206 251 2.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 SUPERFAMILY SSF54736 50 121 1.15E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 Gene3D G3DSA:1.20.5.710 1 50 1.8E-18 T 28-03-2018 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 121 3.9E-51 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 121 25.995 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 Gene3D G3DSA:3.30.1390.10 51 121 6.2E-32 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 2.0E-25 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 2.6E-31 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 SUPERFAMILY SSF48300 1 57 2.35E-19 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06425 e2089c0792f2092efc70c6189915eca8 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 2.4E-21 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS04220 e8f3957bc165064b878104c65b9150fd 536 Pfam PF05598 Transposase domain (DUF772) 62 129 1.5E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS04220 e8f3957bc165064b878104c65b9150fd 536 Pfam PF13751 Transposase DDE domain 393 518 5.5E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS04220 e8f3957bc165064b878104c65b9150fd 536 Gene3D G3DSA:3.90.350.10 230 497 2.0E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS03155 7147933562677d3b331fafd1961884c3 187 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 4 182 8.2E-79 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 A21D_RS03155 7147933562677d3b331fafd1961884c3 187 Gene3D G3DSA:1.10.340.30 3 184 2.8E-86 T 28-03-2018 A21D_RS03155 7147933562677d3b331fafd1961884c3 187 SUPERFAMILY SSF48150 4 183 6.51E-82 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A21D_RS03155 7147933562677d3b331fafd1961884c3 187 Pfam PF03352 Methyladenine glycosylase 8 183 4.8E-84 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 286 1.2E-82 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 SUPERFAMILY SSF53790 14 229 3.66E-80 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 PIRSF PIRSF005917 1 288 1.2E-102 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 Gene3D G3DSA:3.30.950.10 122 234 2.6E-38 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 Gene3D G3DSA:3.40.1010.10 11 121 7.2E-41 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 212 6.9E-27 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06825 093c2aeb4340b6a92dd8b9d8baf6582b 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 231 36.645 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 SUPERFAMILY SSF52540 28 246 8.12E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 Gene3D G3DSA:3.40.50.300 337 495 4.5E-36 T 28-03-2018 A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 SMART SM00487 57 233 1.1E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 Pfam PF00176 SNF2 family N-terminal domain 77 296 9.4E-37 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 SUPERFAMILY SSF52540 169 223 3.24E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 SUPERFAMILY SSF52540 341 509 3.24E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 Gene3D G3DSA:3.40.50.10810 42 274 6.3E-37 T 28-03-2018 A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 Pfam PF00271 Helicase conserved C-terminal domain 354 458 8.1E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS15995 5dba78fe133b583a0410015d24884cd7 552 SMART SM00490 378 458 1.9E-19 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS10685 346e501bd0aa5a3faf75b00bec863bc2 311 Pfam PF13407 Periplasmic binding protein domain 43 297 5.6E-67 T 28-03-2018 IPR025997 Periplasmic binding protein A21D_RS10685 346e501bd0aa5a3faf75b00bec863bc2 311 SUPERFAMILY SSF53822 37 310 8.04E-91 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS10685 346e501bd0aa5a3faf75b00bec863bc2 311 Gene3D G3DSA:3.40.50.2300 156 308 5.4E-42 T 28-03-2018 A21D_RS10685 346e501bd0aa5a3faf75b00bec863bc2 311 Gene3D G3DSA:3.40.50.2300 36 155 2.9E-31 T 28-03-2018 A21D_RS13365 90290627e550013e68abd9cb05ec0beb 87 Gene3D G3DSA:3.30.1370.70 2 86 2.4E-20 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS13365 90290627e550013e68abd9cb05ec0beb 87 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 85 4.0E-22 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS13365 90290627e550013e68abd9cb05ec0beb 87 SMART SM00932 3 86 5.0E-14 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS13365 90290627e550013e68abd9cb05ec0beb 87 SUPERFAMILY SSF110836 3 84 4.05E-23 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 PIRSF PIRSF000521 2 451 1.2E-32 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 Pfam PF00202 Aminotransferase class-III 30 447 1.2E-106 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 Gene3D G3DSA:3.40.640.10 82 326 6.5E-73 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 Gene3D G3DSA:3.90.1150.10 327 457 9.3E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 Gene3D G3DSA:3.90.1150.10 1 81 6.3E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 SUPERFAMILY SSF53383 8 451 6.68E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS12130 990e1a102a2c6ff18e69300a4b819889 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 289 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS16850 60b2f904d257b4631a336fc0cd635a9b 173 SUPERFAMILY SSF55729 3 165 5.32E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS16850 60b2f904d257b4631a336fc0cd635a9b 173 Pfam PF13302 Acetyltransferase (GNAT) domain 3 143 8.5E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS16850 60b2f904d257b4631a336fc0cd635a9b 173 Gene3D G3DSA:3.40.630.30 41 170 8.9E-17 T 28-03-2018 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 SMART SM00382 505 689 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Pfam PF03412 Peptidase C39 family 6 137 6.9E-26 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 SUPERFAMILY SSF52540 473 680 1.07E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Gene3D G3DSA:3.90.70.10 9 146 3.9E-22 T 28-03-2018 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Pfam PF00664 ABC transporter transmembrane region 165 434 2.8E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Gene3D G3DSA:3.40.50.300 464 693 1.3E-55 T 28-03-2018 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 SUPERFAMILY SSF90123 621 629 1.7E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 SUPERFAMILY SSF90123 152 445 1.7E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Pfam PF00005 ABC transporter 496 644 5.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 Gene3D G3DSA:1.20.1560.10 147 461 2.4E-36 T 28-03-2018 A21D_RS07795 48faf1985c935dd934c939626663e34f 696 ProSitePatterns PS00211 ABC transporters family signature. 617 631 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 51 110 1.1E-8 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 224 3.4E-16 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Gene3D G3DSA:1.10.760.10 263 349 7.9E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 SUPERFAMILY SSF46626 246 341 7.77E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 SUPERFAMILY SSF49503 124 287 1.44E-46 T 28-03-2018 IPR008972 Cupredoxin A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 41 234 1.2E-58 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Gene3D G3DSA:2.60.40.420 117 262 5.8E-47 T 28-03-2018 IPR008972 Cupredoxin A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 SUPERFAMILY SSF81464 18 116 8.67E-19 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 170 218 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Gene3D G3DSA:1.10.287.90 30 116 1.4E-20 T 28-03-2018 A21D_RS18550 683a6d3c58b5c5326b0994643e486dc3 350 Pfam PF00034 Cytochrome c 251 339 3.5E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Gene3D G3DSA:3.40.50.620 27 212 1.2E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 SUPERFAMILY SSF52374 11 197 1.01E-135 T 28-03-2018 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 SUPERFAMILY SSF52374 383 636 1.01E-135 T 28-03-2018 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 SUPERFAMILY SSF47323 944 1022 2.81E-5 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 3.4E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 548 557 3.4E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 3.4E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 508 521 3.4E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 381 396 3.4E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 4 1023 13.572 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Gene3D G3DSA:1.10.730.10 574 811 3.8E-60 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 SUPERFAMILY SSF50677 199 383 1.15E-48 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 621 4.0E-189 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 828 6.5E-285 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Gene3D G3DSA:3.90.740.10 213 480 3.7E-89 T 28-03-2018 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 Pfam PF08264 Anticodon-binding domain of tRNA 674 816 1.4E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A21D_RS03900 d9d88dc19b6e194272e46700e905a8c3 1027 SUPERFAMILY SSF47323 644 876 1.2E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 Gene3D G3DSA:3.30.70.580 1 106 3.1E-33 T 28-03-2018 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 Pfam PF01416 tRNA pseudouridine synthase 144 246 1.6E-27 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 Pfam PF01416 tRNA pseudouridine synthase 9 105 2.3E-12 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 Gene3D G3DSA:3.30.70.660 107 245 7.6E-38 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 241 3.7E-66 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 PIRSF PIRSF001430 1 246 1.5E-80 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 35.122 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06215 55249f501da7a8dd5d33285789c9683b 246 SUPERFAMILY SSF55120 2 246 7.77E-81 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS06820 33e8ab533d3ce7f0cc9012d9332cb331 92 SMART SM00966 8 51 3.9E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06820 33e8ab533d3ce7f0cc9012d9332cb331 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 3.2E-11 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06820 33e8ab533d3ce7f0cc9012d9332cb331 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 7.3E-12 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06820 33e8ab533d3ce7f0cc9012d9332cb331 92 Gene3D G3DSA:2.10.260.10 1 48 4.0E-18 T 28-03-2018 A21D_RS06820 33e8ab533d3ce7f0cc9012d9332cb331 92 SUPERFAMILY SSF89447 2 52 5.1E-16 T 28-03-2018 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 SMART SM00342 228 311 5.4E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 SUPERFAMILY SSF46689 212 262 9.32E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 SUPERFAMILY SSF46689 265 315 1.79E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 Gene3D G3DSA:3.90.1240.10 111 320 6.3E-31 T 28-03-2018 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 Pfam PF12833 Helix-turn-helix domain 234 312 6.4E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS06060 06aaba63541ad2508f7b58894639620a 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS17960 14766fbbd5ec485077c39bbee88399ca 132 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 129 1.6E-32 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A21D_RS17960 14766fbbd5ec485077c39bbee88399ca 132 Pfam PF00460 Flagella basal body rod protein 25 38 2.3E-4 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS17960 14766fbbd5ec485077c39bbee88399ca 132 PIRSF PIRSF002889 1 131 2.8E-34 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 SUPERFAMILY SSF52540 5 462 3.58E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Gene3D G3DSA:1.10.8.10 123 222 1.1E-27 T 28-03-2018 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 356 427 4.9E-8 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 464 5.1E-208 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Gene3D G3DSA:3.40.50.300 8 122 1.7E-12 T 28-03-2018 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Gene3D G3DSA:1.10.8.10 223 265 2.5E-14 T 28-03-2018 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 SMART SM00382 50 337 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Pfam PF07724 AAA domain (Cdc48 subfamily) 210 350 1.5E-40 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 108 6.0E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 SMART SM01086 356 452 3.5E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Gene3D G3DSA:1.10.8.60 356 452 4.2E-31 T 28-03-2018 A21D_RS17975 c85be4f01ff0fbda65a7353619c85a28 464 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 464 43.6 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A21D_RS14645 a62277a50d2ab0704097f6787f4a9271 308 SUPERFAMILY SSF52540 127 276 4.33E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14645 a62277a50d2ab0704097f6787f4a9271 308 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 5.7E-27 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal A21D_RS14645 a62277a50d2ab0704097f6787f4a9271 308 SMART SM00382 159 287 2.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14645 a62277a50d2ab0704097f6787f4a9271 308 Pfam PF01695 IstB-like ATP binding protein 127 274 3.1E-12 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A21D_RS14645 a62277a50d2ab0704097f6787f4a9271 308 Gene3D G3DSA:3.40.50.300 108 301 8.0E-23 T 28-03-2018 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 SUPERFAMILY SSF52540 10 204 1.61E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 166 1.2E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 95 8.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 8.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 Gene3D G3DSA:3.30.300.20 198 298 4.9E-47 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 Gene3D G3DSA:3.40.50.300 9 197 1.2E-36 T 28-03-2018 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 Pfam PF01926 50S ribosome-binding GTPase 10 124 1.9E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 8 278 6.6E-108 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 SUPERFAMILY SSF54814 180 295 2.16E-43 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 Hamap MF_00367 GTPase Era [era]. 5 295 38.364 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15725 4ea68d26e232540854a5cc671f98adf1 300 Pfam PF07650 KH domain 207 284 1.9E-22 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 Pfam PF00701 Dihydrodipicolinate synthetase family 15 299 3.4E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 Gene3D G3DSA:3.20.20.70 3 306 9.6E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 PIRSF PIRSF001365 12 308 9.7E-86 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 146 177 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 15 305 4.2E-154 T 28-03-2018 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 18 301 1.8E-91 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 SMART SM01130 14 303 3.7E-120 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 SUPERFAMILY SSF51569 15 302 3.35E-93 T 28-03-2018 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 14 301 53.65 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 116 132 3.8E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 141 158 3.8E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 84 102 3.8E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS19380 5076fe71cc0816a2cbb89f6116dbed54 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 48 69 3.8E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 73 3.5E-21 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 Gene3D G3DSA:3.40.50.10490 73 254 6.4E-23 T 28-03-2018 A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 Pfam PF01380 SIS domain 109 223 7.4E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 SUPERFAMILY SSF53697 81 249 3.84E-25 T 28-03-2018 A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 Gene3D G3DSA:1.10.10.10 1 72 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07105 e7646fa64ed56c4011c9b6782b8b082c 255 SUPERFAMILY SSF46689 1 76 4.48E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 SUPERFAMILY SSF52374 411 624 2.71E-141 T 28-03-2018 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 SUPERFAMILY SSF52374 2 224 2.71E-141 T 28-03-2018 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 5.6E-70 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Gene3D G3DSA:3.90.740.10 224 398 1.4E-62 T 28-03-2018 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 2.8E-17 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 2.4E-18 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Gene3D G3DSA:3.40.50.620 399 564 3.1E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Gene3D G3DSA:3.90.740.10 180 223 0.0021 T 28-03-2018 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Pfam PF08264 Anticodon-binding domain of tRNA 655 766 1.6E-21 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 SUPERFAMILY SSF47323 618 803 5.42E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.202 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Gene3D G3DSA:1.10.730.10 565 803 1.6E-63 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 SUPERFAMILY SSF50677 224 410 7.01E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 Gene3D G3DSA:3.40.50.620 30 179 1.6E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.3E-57 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS14190 96132ce32021945208298e13a7c97f22 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 803 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A21D_RS10370 63dae73b19a4c66509222fee1e5188b5 286 Pfam PF03592 Terminase small subunit 79 251 3.6E-43 T 28-03-2018 IPR005335 Terminase small subunit GO:0006323 A21D_RS01220 7be65b5f0f5b19cedfecb4601cdf48fd 287 Gene3D G3DSA:1.10.10.10 223 282 1.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01220 7be65b5f0f5b19cedfecb4601cdf48fd 287 PIRSF PIRSF012524 1 284 2.3E-92 T 28-03-2018 IPR014464 Conserved virulence factor B A21D_RS01220 7be65b5f0f5b19cedfecb4601cdf48fd 287 Pfam PF13509 S1 domain 6 64 1.1E-17 T 28-03-2018 A21D_RS01220 7be65b5f0f5b19cedfecb4601cdf48fd 287 Gene3D G3DSA:2.40.50.140 66 222 1.6E-10 T 28-03-2018 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Pfam PF04542 Sigma-70 region 2 140 209 3.1E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Pfam PF00140 Sigma-70 factor, region 1.2 102 135 1.8E-17 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 PRINTS PR00046 Major sigma-70 factor signature 348 359 3.1E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 PRINTS PR00046 Major sigma-70 factor signature 164 177 3.1E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 PRINTS PR00046 Major sigma-70 factor signature 188 196 3.1E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 PRINTS PR00046 Major sigma-70 factor signature 333 348 3.1E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 PRINTS PR00046 Major sigma-70 factor signature 312 324 3.1E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Gene3D G3DSA:1.10.601.10 1 209 1.1E-74 T 28-03-2018 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Gene3D G3DSA:1.10.10.10 210 260 1.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Pfam PF04545 Sigma-70, region 4 308 361 5.2E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Pfam PF04539 Sigma-70 region 3 219 295 4.8E-32 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 136 372 4.0E-124 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 SUPERFAMILY SSF88659 270 372 4.67E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Pfam PF03979 Sigma-70 factor, region 1.1 20 84 1.0E-14 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Gene3D G3DSA:1.10.10.10 302 373 3.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 8 373 34.189 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 164 177 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 333 359 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 136 361 1.2E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 SUPERFAMILY SSF88659 213 286 8.22E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS15765 e4af88c9f06356eeec78aa8376e29871 374 SUPERFAMILY SSF88946 101 210 1.96E-53 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 SMART SM00865 207 324 4.8E-55 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 Gene3D G3DSA:3.30.1330.20 215 324 6.8E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 SMART SM00864 13 205 2.1E-119 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 PRINTS PR00423 Cell division protein FtsZ signature 212 233 3.3E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 PRINTS PR00423 Cell division protein FtsZ signature 126 147 3.3E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 PRINTS PR00423 Cell division protein FtsZ signature 189 211 3.3E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 PRINTS PR00423 Cell division protein FtsZ signature 98 118 3.3E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 335 6.1E-140 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 370 39.579 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 Gene3D G3DSA:3.40.50.1440 8 214 1.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 SUPERFAMILY SSF55307 204 319 4.58E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 SUPERFAMILY SSF52490 12 208 6.67E-73 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 3.7E-45 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A21D_RS18370 9a218c9b64b21efc2986123ea9669e89 384 Pfam PF12327 FtsZ family, C-terminal domain 222 316 1.7E-33 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 SUPERFAMILY SSF51735 122 279 4.17E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 39.132 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 SUPERFAMILY SSF53223 2 121 1.63E-38 T 28-03-2018 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.3E-71 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 Gene3D G3DSA:3.40.50.10860 11 138 3.3E-47 T 28-03-2018 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.2E-40 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 Gene3D G3DSA:3.40.50.720 139 263 8.0E-39 T 28-03-2018 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS16110 7c95fded50c815f3b31cb12caacdeabe 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.6E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A21D_RS01275 6214bb8db935550f5034d6c50dd8d05f 208 SMART SM01120 32 200 4.3E-60 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS01275 6214bb8db935550f5034d6c50dd8d05f 208 SUPERFAMILY SSF101473 3 201 1.57E-53 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS01275 6214bb8db935550f5034d6c50dd8d05f 208 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 199 6.1E-73 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 A21D_RS01275 6214bb8db935550f5034d6c50dd8d05f 208 Pfam PF02734 DAK2 domain 32 199 1.5E-49 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS08645 dcee325144f35e63d6e74b80e3ed5641 290 Gene3D G3DSA:3.40.630.30 1 134 3.0E-4 T 28-03-2018 A21D_RS08645 dcee325144f35e63d6e74b80e3ed5641 290 SUPERFAMILY SSF55729 132 284 1.27E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS08645 dcee325144f35e63d6e74b80e3ed5641 290 Gene3D G3DSA:3.40.630.30 135 280 1.8E-18 T 28-03-2018 A21D_RS08645 dcee325144f35e63d6e74b80e3ed5641 290 Pfam PF02388 FemAB family 124 175 4.8E-6 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 A21D_RS03910 82ddae1d579a3091153643a471f87327 766 Gene3D G3DSA:3.40.50.300 210 591 7.1E-32 T 28-03-2018 A21D_RS03910 82ddae1d579a3091153643a471f87327 766 Gene3D G3DSA:3.40.50.300 595 766 1.4E-21 T 28-03-2018 A21D_RS03910 82ddae1d579a3091153643a471f87327 766 Pfam PF13245 AAA domain 216 574 2.7E-10 T 28-03-2018 A21D_RS03910 82ddae1d579a3091153643a471f87327 766 SUPERFAMILY SSF52540 512 748 2.0E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03910 82ddae1d579a3091153643a471f87327 766 SUPERFAMILY SSF52540 382 410 2.0E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03910 82ddae1d579a3091153643a471f87327 766 SUPERFAMILY SSF52540 204 325 2.0E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03910 82ddae1d579a3091153643a471f87327 766 Pfam PF13538 UvrD-like helicase C-terminal domain 696 744 5.6E-8 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 6.3E-154 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 SUPERFAMILY SSF52009 466 584 2.75E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Gene3D G3DSA:3.20.20.60 1 112 3.3E-20 T 28-03-2018 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Gene3D G3DSA:3.40.1380.20 322 474 8.5E-55 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 505 576 2.7E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Gene3D G3DSA:3.20.20.60 166 321 1.1E-64 T 28-03-2018 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 471 6.9E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 2.2E-80 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Gene3D G3DSA:2.40.33.10 113 165 7.9E-22 T 28-03-2018 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 473 3.2E-187 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 SUPERFAMILY SSF51621 1 75 6.28E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 SUPERFAMILY SSF51621 167 341 6.28E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 Gene3D G3DSA:3.50.30.10 475 586 6.3E-31 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 SUPERFAMILY SSF52935 323 474 6.28E-43 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 SUPERFAMILY SSF50800 71 167 1.74E-25 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain A21D_RS14560 f67b366d516ce7c5b1224e3d9b5f8dae 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A21D_RS04580 62ee72768dd99b552842f42f4db3aa95 372 Gene3D G3DSA:3.40.50.2000 208 347 2.4E-42 T 28-03-2018 A21D_RS04580 62ee72768dd99b552842f42f4db3aa95 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 30 366 1.4E-121 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 A21D_RS04580 62ee72768dd99b552842f42f4db3aa95 372 Gene3D G3DSA:3.40.50.2000 6 207 2.3E-79 T 28-03-2018 A21D_RS04580 62ee72768dd99b552842f42f4db3aa95 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 6 366 1.7E-161 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A21D_RS04580 62ee72768dd99b552842f42f4db3aa95 372 SUPERFAMILY SSF53756 5 370 1.67E-137 T 28-03-2018 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 SUPERFAMILY SSF54675 18 128 5.49E-23 T 28-03-2018 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 115 5.7E-8 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 Gene3D G3DSA:3.90.1170.20 2 131 4.6E-24 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 PIRSF PIRSF000484 15 83 1.6E-6 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 PIRSF PIRSF000484 75 343 3.3E-54 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 SUPERFAMILY SSF51690 125 355 4.42E-43 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A21D_RS14315 4458f46d63b5ddd4ff505c1a70ebea5a 370 Gene3D G3DSA:3.20.20.70 132 334 1.9E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS13240 8292f44cc9103bd19d4b5d543189db53 603 Pfam PF08439 Oligopeptidase F 114 183 2.5E-18 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A21D_RS13240 8292f44cc9103bd19d4b5d543189db53 603 SUPERFAMILY SSF55486 5 581 2.87E-103 T 28-03-2018 A21D_RS13240 8292f44cc9103bd19d4b5d543189db53 603 Pfam PF01432 Peptidase family M3 209 585 3.9E-41 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A21D_RS13240 8292f44cc9103bd19d4b5d543189db53 603 Gene3D G3DSA:1.10.1370.10 94 587 1.1E-26 T 28-03-2018 A21D_RS13240 8292f44cc9103bd19d4b5d543189db53 603 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 7 597 1.3E-197 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A21D_RS09950 48ed71a7c8584fef56741e8b21b2f5bc 105 SUPERFAMILY SSF52833 2 78 6.9E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS09950 48ed71a7c8584fef56741e8b21b2f5bc 105 Pfam PF00462 Glutaredoxin 6 62 7.3E-9 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A21D_RS09950 48ed71a7c8584fef56741e8b21b2f5bc 105 Gene3D G3DSA:3.40.30.10 5 89 6.0E-14 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 332 346 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 530 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 640 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 551 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 656 2.6E-38 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF81653 113 222 2.48E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF56784 475 725 8.24E-57 T 28-03-2018 IPR023214 HAD-like domain A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF56784 330 350 8.24E-57 T 28-03-2018 IPR023214 HAD-like domain A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 592 709 2.0E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 362 3.2E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Gene3D G3DSA:1.20.1110.10 525 878 7.8E-84 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 621 637 7.3E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 478 496 7.3E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 593 609 7.3E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 652 677 7.3E-15 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 69 1.2E-18 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF81665 223 326 2.48E-117 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF81665 670 877 2.48E-117 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF81665 3 113 2.48E-117 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Gene3D G3DSA:2.70.150.10 11 223 2.2E-48 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 334 340 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Gene3D G3DSA:3.40.1110.10 294 524 4.3E-52 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Pfam PF00122 E1-E2 ATPase 110 312 4.6E-54 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 635 6.6E-22 T 28-03-2018 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 Pfam PF00689 Cation transporting ATPase, C-terminus 704 873 4.0E-40 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SMART SM00831 2 75 9.8E-25 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A21D_RS09565 4643dd0dcbaf679f90ec42ec905d7017 878 SUPERFAMILY SSF81660 341 527 3.92E-48 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS15015 54ca78131c766cc74fc67c4fe2a21993 78 SUPERFAMILY SSF52833 4 73 7.42E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS15015 54ca78131c766cc74fc67c4fe2a21993 78 Pfam PF00462 Glutaredoxin 6 64 6.2E-16 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A21D_RS15015 54ca78131c766cc74fc67c4fe2a21993 78 Gene3D G3DSA:3.40.30.10 2 78 7.0E-19 T 28-03-2018 A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 Gene3D G3DSA:1.10.443.10 172 370 4.2E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 62 117 5.1E-11 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 SUPERFAMILY SSF56349 61 367 3.06E-64 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 Pfam PF14657 Arm DNA-binding domain 10 48 1.0E-9 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 Gene3D G3DSA:1.10.150.130 55 171 1.8E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS00215 8ec8bce67d643ee92e41acef2f6f16ea 377 Pfam PF00589 Phage integrase family 169 361 5.0E-29 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS17010 72de95914e13418aef069c0251cf5285 509 SUPERFAMILY SSF52096 236 508 4.41E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS17010 72de95914e13418aef069c0251cf5285 509 Gene3D G3DSA:3.90.226.10 249 508 9.4E-69 T 28-03-2018 A21D_RS17010 72de95914e13418aef069c0251cf5285 509 Gene3D G3DSA:3.90.226.10 4 248 3.0E-57 T 28-03-2018 A21D_RS17010 72de95914e13418aef069c0251cf5285 509 Pfam PF01039 Carboxyl transferase domain 26 506 1.4E-157 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A21D_RS17010 72de95914e13418aef069c0251cf5285 509 SUPERFAMILY SSF52096 9 246 7.97E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 SUPERFAMILY SSF81891 141 394 3.4E-44 T 28-03-2018 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 228 2.5E-11 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 268 391 3.6E-23 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Pfam PF01743 Poly A polymerase head domain 23 143 1.1E-36 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Hamap MF_01263 CCA-adding enzyme [cca]. 3 396 35.2 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 SUPERFAMILY SSF81301 7 139 5.23E-42 T 28-03-2018 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Gene3D G3DSA:3.30.460.10 4 142 5.5E-47 T 28-03-2018 A21D_RS16720 5c83a9de6ee17d935afd58d930f183e8 400 Gene3D G3DSA:1.10.3090.10 143 387 7.2E-37 T 28-03-2018 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 117 27.256 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 117 9.6E-49 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 ProSitePatterns PS01167 Ribosomal protein L17 signature. 29 51 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 Pfam PF01196 Ribosomal protein L17 15 117 2.3E-40 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 Gene3D G3DSA:3.90.1030.10 1 117 2.9E-49 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06235 9fa15d78514561cb28a2374353f24428 117 SUPERFAMILY SSF64263 3 117 1.57E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS03725 c7553b686740ab5824558c390b7c52fe 174 Gene3D G3DSA:3.40.630.30 16 171 8.3E-14 T 28-03-2018 A21D_RS03725 c7553b686740ab5824558c390b7c52fe 174 Pfam PF13302 Acetyltransferase (GNAT) domain 68 151 6.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS03725 c7553b686740ab5824558c390b7c52fe 174 SUPERFAMILY SSF55729 60 160 3.6E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 395 1.7E-144 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 Gene3D G3DSA:3.40.50.10300 182 402 1.1E-66 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 SUPERFAMILY SSF52507 3 177 1.31E-61 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 SUPERFAMILY SSF102645 187 399 2.09E-70 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 369 4.7E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 Pfam PF02441 Flavoprotein 5 175 4.7E-46 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS18205 809505e1b4c9e0f840f9122335eb4c4c 402 Gene3D G3DSA:3.40.50.1950 2 181 2.2E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A21D_RS06705 b3903380f5fac4cc4724ba6c18d25a6e 199 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 130 9.6E-38 T 28-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ A21D_RS06705 b3903380f5fac4cc4724ba6c18d25a6e 199 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 88 4.8E-17 T 28-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 SMART SM00436 126 216 4.2E-39 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Pfam PF01131 DNA topoisomerase 152 580 5.3E-124 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Gene3D G3DSA:2.70.20.10 351 473 1.0E-31 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 724 2.1E-261 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 SMART SM00437 262 546 6.0E-85 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Gene3D G3DSA:3.30.65.10 592 649 2.1E-7 T 28-03-2018 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 SMART SM00493 3 126 3.5E-17 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Pfam PF01751 Toprim domain 5 134 1.1E-14 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Gene3D G3DSA:1.10.460.10 159 339 1.4E-40 T 28-03-2018 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Gene3D G3DSA:3.40.50.140 3 154 7.4E-41 T 28-03-2018 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.1E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 1.1E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.1E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 509 523 1.1E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 1.1E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 SUPERFAMILY SSF56712 3 595 2.22E-178 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A21D_RS01205 31d2b7e69d23f8779b7958236093b49d 726 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 635 64.28 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A21D_RS10555 f01821e431e347450fac00fbc7f8a5db 79 Gene3D G3DSA:1.10.150.130 40 79 9.3E-4 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS08025 5d8eada00db76ce7418ed38fd156b6ad 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 91 1.4E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS08025 5d8eada00db76ce7418ed38fd156b6ad 101 SUPERFAMILY SSF52794 1 98 2.62E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS08025 5d8eada00db76ce7418ed38fd156b6ad 101 Gene3D G3DSA:3.40.50.2300 1 101 9.7E-30 T 28-03-2018 A21D_RS11265 e2a4c2cccf7dcedbe5d4e268718da11d 432 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 424 1.1E-112 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS11265 e2a4c2cccf7dcedbe5d4e268718da11d 432 PIRSF PIRSF006351 1 431 6.0E-138 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS11265 e2a4c2cccf7dcedbe5d4e268718da11d 432 Pfam PF02378 Phosphotransferase system, EIIC 30 349 2.7E-50 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS12830 5f8a270fb517eceeeb9f52040db61959 283 Pfam PF12671 Putative amidase domain 124 277 3.4E-39 T 28-03-2018 IPR024301 Putative amidase domain A21D_RS12830 5f8a270fb517eceeeb9f52040db61959 283 Gene3D G3DSA:3.90.1720.10 117 281 1.8E-16 T 28-03-2018 A21D_RS00945 3804a334633069330b6bf972666839a7 312 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 230 1.8E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS00945 3804a334633069330b6bf972666839a7 312 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 229 1.8E-49 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS13510 1515338fccdc3b6e8c3d252443dce985 202 SMART SM00954 42 163 8.7E-44 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A21D_RS13510 1515338fccdc3b6e8c3d252443dce985 202 SUPERFAMILY SSF81301 2 197 1.34E-58 T 28-03-2018 A21D_RS13510 1515338fccdc3b6e8c3d252443dce985 202 Gene3D G3DSA:3.30.460.10 1 144 8.0E-39 T 28-03-2018 A21D_RS13510 1515338fccdc3b6e8c3d252443dce985 202 Gene3D G3DSA:1.10.287.860 146 194 7.3E-18 T 28-03-2018 A21D_RS13510 1515338fccdc3b6e8c3d252443dce985 202 Pfam PF04607 Region found in RelA / SpoT proteins 42 161 1.3E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A21D_RS17125 92c9bd0d399a89543aeb43ae0f8813d9 157 Pfam PF11084 Protein of unknown function (DUF2621) 6 140 1.5E-68 T 28-03-2018 IPR020203 Uncharacterised protein family, YneK A21D_RS17125 92c9bd0d399a89543aeb43ae0f8813d9 157 ProDom PD086666 YNEK BH2332 10 143 9.0E-45 T 28-03-2018 IPR020203 Uncharacterised protein family, YneK A21D_RS01540 a81fb7e5e53f70a81686134a798d035d 322 Pfam PF08378 Nuclease-related domain 41 153 4.8E-16 T 28-03-2018 IPR011528 Nuclease-related domain, NERD A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Gene3D G3DSA:3.10.150.10 1 129 5.3E-29 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 1.1E-35 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 2.0E-35 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 3.8E-34 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 4.4E-113 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 SUPERFAMILY SSF55979 133 251 4.52E-27 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Gene3D G3DSA:3.10.150.10 130 256 1.6E-33 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 Gene3D G3DSA:3.10.150.10 257 378 1.3E-25 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 SMART SM00480 17 373 2.9E-142 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 SUPERFAMILY SSF55979 1 127 6.06E-24 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 SUPERFAMILY SSF55979 254 377 1.26E-31 T 28-03-2018 A21D_RS07225 f6586dc1403a6578a0371e803f8d4b83 378 PIRSF PIRSF000804 1 378 2.3E-114 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS06695 b2d25233091bce73566922cf212a5d3b 129 SMART SM00316 4 74 2.3E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS06695 b2d25233091bce73566922cf212a5d3b 129 Gene3D G3DSA:2.40.50.140 7 120 7.1E-27 T 28-03-2018 A21D_RS06695 b2d25233091bce73566922cf212a5d3b 129 SUPERFAMILY SSF50249 4 83 2.81E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06695 b2d25233091bce73566922cf212a5d3b 129 Pfam PF00575 S1 RNA binding domain 4 74 3.2E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS06885 b9f2bf2ad43b7b92022a50a637709ff6 70 Pfam PF10704 Protein of unknown function (DUF2508) 3 66 1.1E-12 T 28-03-2018 IPR019644 Protein of unknown function DUF2508 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 4.5E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 4.5E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 4.5E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 4.5E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 388 408 4.5E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 SUPERFAMILY SSF161070 4 491 2.35E-134 T 28-03-2018 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 Pfam PF00209 Sodium:neurotransmitter symporter family 150 483 5.9E-66 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13860 06ec37a5a253fba90a2584e0c2b60194 509 Pfam PF00209 Sodium:neurotransmitter symporter family 4 121 2.2E-38 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS13575 44beb91d901a979cb6e994a528f9127d 241 Pfam PF00756 Putative esterase 14 236 5.5E-45 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A21D_RS13575 44beb91d901a979cb6e994a528f9127d 241 Gene3D G3DSA:3.40.50.1820 3 241 2.7E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS13575 44beb91d901a979cb6e994a528f9127d 241 SUPERFAMILY SSF53474 5 237 9.67E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SMART SM00636 150 453 1.1E-29 T 28-03-2018 IPR011583 Chitinase II GO:0008061 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Gene3D G3DSA:3.10.350.10 99 140 1.3E-11 T 28-03-2018 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Gene3D G3DSA:3.20.20.80 141 463 1.8E-53 T 28-03-2018 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Pfam PF01476 LysM domain 4 47 7.6E-15 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Pfam PF01476 LysM domain 53 96 2.5E-10 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Pfam PF01476 LysM domain 100 143 3.8E-10 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Gene3D G3DSA:3.10.350.10 2 50 1.2E-16 T 28-03-2018 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SUPERFAMILY SSF54106 3 47 5.36E-12 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Pfam PF00704 Glycosyl hydrolases family 18 222 450 3.5E-25 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 Gene3D G3DSA:3.10.350.10 51 98 2.3E-12 T 28-03-2018 A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SMART SM00257 3 47 1.9E-17 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SMART SM00257 52 96 8.8E-9 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SMART SM00257 99 143 5.3E-9 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SUPERFAMILY SSF54106 52 96 1.23E-9 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SUPERFAMILY SSF54106 98 144 1.57E-9 T 28-03-2018 IPR018392 LysM domain A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SUPERFAMILY SSF51445 425 468 7.54E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS03125 e371a7b75226b6a06449f694ec990655 470 SUPERFAMILY SSF51445 166 366 7.54E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS09330 6699be02d02e12a5096bb1cdb8fcf7fd 399 SUPERFAMILY SSF53649 1 96 3.14E-48 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS09330 6699be02d02e12a5096bb1cdb8fcf7fd 399 SUPERFAMILY SSF53649 226 396 3.14E-48 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS09330 6699be02d02e12a5096bb1cdb8fcf7fd 399 Pfam PF01676 Metalloenzyme superfamily 3 384 1.6E-32 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A21D_RS09330 6699be02d02e12a5096bb1cdb8fcf7fd 399 PIRSF PIRSF001491 1 397 1.3E-93 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS09330 6699be02d02e12a5096bb1cdb8fcf7fd 399 Gene3D G3DSA:3.40.720.10 1 397 1.2E-33 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS08260 406999271d0fef71c925ccba536cce36 347 Gene3D G3DSA:3.40.190.10 40 136 9.3E-5 T 28-03-2018 A21D_RS08260 406999271d0fef71c925ccba536cce36 347 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 42 340 1.2E-57 T 28-03-2018 A21D_RS08260 406999271d0fef71c925ccba536cce36 347 Gene3D G3DSA:3.40.190.10 137 255 3.2E-13 T 28-03-2018 A21D_RS08260 406999271d0fef71c925ccba536cce36 347 SUPERFAMILY SSF53850 37 344 1.52E-36 T 28-03-2018 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 PIRSF PIRSF016184 1 289 1.3E-77 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 Gene3D G3DSA:3.10.310.10 1 126 8.6E-33 T 28-03-2018 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 Pfam PF02567 Phenazine biosynthesis-like protein 8 278 4.2E-59 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 286 2.8E-66 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 SUPERFAMILY SSF54506 1 284 5.89E-70 T 28-03-2018 A21D_RS05220 caf12abb1b2bf96c4d377c3186e9b932 289 Gene3D G3DSA:3.10.310.10 127 278 9.6E-33 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Gene3D G3DSA:1.10.8.60 435 504 1.0E-23 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SUPERFAMILY SSF52540 262 505 1.52E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Gene3D G3DSA:1.10.10.60 505 573 1.9E-17 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Pfam PF00989 PAS fold 124 191 1.8E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Gene3D G3DSA:3.10.580.10 1 108 1.5E-8 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 176 3.0E-8 T 28-03-2018 IPR000014 PAS domain A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SUPERFAMILY SSF46689 476 572 1.36E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SMART SM00091 122 188 1.6E-6 T 28-03-2018 IPR000014 PAS domain A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SUPERFAMILY SSF54631 1 106 1.7E-11 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Gene3D G3DSA:3.40.50.300 257 434 4.9E-26 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Gene3D G3DSA:3.30.450.20 121 219 6.2E-9 T 28-03-2018 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 553 573 3.3E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 536 553 3.3E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SUPERFAMILY SSF55785 122 216 4.19E-13 T 28-03-2018 IPR000014 PAS domain A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 476 485 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Pfam PF02954 Bacterial regulatory protein, Fis family 533 570 2.0E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 SMART SM00382 282 430 1.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 Pfam PF00158 Sigma-54 interaction domain 262 429 4.1E-68 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A21D_RS12615 f4f6c8893f3032b1ddaa4fc2aa876b4e 575 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 286 299 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A21D_RS17185 02fdff403bc153c118719d1394793a44 272 Pfam PF13411 MerR HTH family regulatory protein 7 73 2.0E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS17185 02fdff403bc153c118719d1394793a44 272 Gene3D G3DSA:1.10.1660.10 61 121 7.0E-5 T 28-03-2018 A21D_RS17185 02fdff403bc153c118719d1394793a44 272 SUPERFAMILY SSF46955 4 113 1.79E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS17185 02fdff403bc153c118719d1394793a44 272 Gene3D G3DSA:1.10.1660.10 1 60 7.4E-18 T 28-03-2018 A21D_RS17185 02fdff403bc153c118719d1394793a44 272 SMART SM00422 6 75 2.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 SUPERFAMILY SSF55909 4 409 6.07E-134 T 28-03-2018 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 TIGRFAM TIGR01078 arcA: arginine deiminase 5 408 1.3E-168 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 Gene3D G3DSA:3.75.10.10 4 407 4.1E-101 T 28-03-2018 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 Pfam PF02274 Amidinotransferase 19 406 1.3E-111 T 28-03-2018 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 345 362 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 388 406 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 365 379 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 3.1E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 Hamap MF_00242 Arginine deiminase [arcA]. 2 409 47.419 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02080 15fe3a56fe2586b2ec1c12f875a90a8d 409 PIRSF PIRSF006356 1 409 7.3E-165 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 SUPERFAMILY SSF52540 67 291 7.11E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 247 273 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 321 344 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 81 109 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 173 197 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 10 34 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 123 140 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 PRINTS PR01874 DNA repair protein radA signature 212 240 5.6E-93 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 SMART SM00382 89 243 1.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 451 3.0E-216 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 Hamap MF_01498 DNA repair protein RadA [radA]. 21 455 45.197 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 Gene3D G3DSA:3.40.50.300 59 241 1.1E-21 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 356 429 9.6E-11 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 Pfam PF13481 AAA domain 81 221 1.3E-14 T 28-03-2018 A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 SUPERFAMILY SSF54211 254 268 1.14E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 SUPERFAMILY SSF54211 302 453 1.14E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS06500 7c029575cbec54cc8473a9b1db02d9c2 457 Gene3D G3DSA:3.30.230.10 242 454 5.4E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 Gene3D G3DSA:3.40.1390.30 1 126 7.5E-38 T 28-03-2018 A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 351 1.2E-86 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 Gene3D G3DSA:3.40.1390.30 226 367 2.5E-13 T 28-03-2018 A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 Gene3D G3DSA:3.30.70.120 134 225 1.6E-40 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 PIRSF PIRSF037489 3 371 1.7E-154 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 SUPERFAMILY SSF102705 6 370 3.79E-130 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A21D_RS15780 de5b3ee3e30860a3f1a84f18a3b5b6a1 371 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 7 367 2.5E-79 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A21D_RS15155 71ae05a2a69f72121f3ad14a18645e26 285 SUPERFAMILY SSF56059 88 281 8.32E-29 T 28-03-2018 A21D_RS15155 71ae05a2a69f72121f3ad14a18645e26 285 Pfam PF08443 RimK-like ATP-grasp domain 110 272 1.3E-20 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A21D_RS15155 71ae05a2a69f72121f3ad14a18645e26 285 Gene3D G3DSA:3.30.470.20 167 270 7.4E-16 T 28-03-2018 A21D_RS15155 71ae05a2a69f72121f3ad14a18645e26 285 Gene3D G3DSA:3.30.1490.20 102 166 1.4E-7 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS15155 71ae05a2a69f72121f3ad14a18645e26 285 Gene3D G3DSA:3.40.50.20 5 101 2.6E-8 T 28-03-2018 A21D_RS08435 01896f50c734fcac5f659c52e7b3c594 246 Pfam PF13580 SIS domain 9 144 3.5E-46 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS08435 01896f50c734fcac5f659c52e7b3c594 246 SUPERFAMILY SSF53697 5 210 7.69E-25 T 28-03-2018 A21D_RS08435 01896f50c734fcac5f659c52e7b3c594 246 Gene3D G3DSA:3.40.50.10490 2 244 6.8E-42 T 28-03-2018 A21D_RS16485 c56ff85d8cfd61d51e0b9a9683560f93 192 PIRSF PIRSF029008 1 192 1.8E-49 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS16485 c56ff85d8cfd61d51e0b9a9683560f93 192 Pfam PF05389 Negative regulator of genetic competence (MecA) 97 187 3.2E-12 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS16485 c56ff85d8cfd61d51e0b9a9683560f93 192 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 87 3.3E-22 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 ProSitePatterns PS00585 Ribosomal protein S5 signature. 29 61 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 SUPERFAMILY SSF54768 9 77 1.46E-24 T 28-03-2018 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 164 36.233 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 Pfam PF00333 Ribosomal protein S5, N-terminal domain 12 76 1.9E-31 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 164 3.1E-71 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 Gene3D G3DSA:3.30.230.10 77 167 3.9E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 158 1.4E-30 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 Gene3D G3DSA:3.30.160.20 11 73 8.5E-30 T 28-03-2018 A21D_RS06290 430ffbb71504ed3f08dc1f521c7a4169 167 SUPERFAMILY SSF54211 81 160 5.82E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 129 143 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 Pfam PF01470 Pyroglutamyl peptidase 2 197 8.2E-60 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 Gene3D G3DSA:3.40.630.20 1 200 5.5E-52 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 1.3E-22 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 1.3E-22 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 161 173 1.3E-22 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 1.3E-22 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 131 147 1.3E-22 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 SUPERFAMILY SSF53182 1 198 8.11E-59 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A21D_RS00980 4d828b3eacd02089d5eb75f941adb926 200 PIRSF PIRSF015592 1 200 2.1E-68 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.061 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.2E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 PIRSF PIRSF002161 1 179 5.3E-70 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 Gene3D G3DSA:3.30.1440.10 1 179 3.3E-81 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 SUPERFAMILY SSF55282 4 178 1.32E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06315 77cede20995769ba351c729dd1fbe104 179 Pfam PF00281 Ribosomal protein L5 24 80 2.3E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 SMART SM00382 141 269 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 142 162 8.9E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 174 188 8.9E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 403 422 8.9E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 206 220 8.9E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 240 267 8.9E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Gene3D G3DSA:3.40.50.300 106 273 8.1E-24 T 28-03-2018 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Pfam PF11638 DnaA N-terminal domain 5 67 6.3E-19 T 28-03-2018 IPR024633 DnaA N-terminal domain A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Pfam PF00308 Bacterial dnaA protein 109 325 5.5E-107 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 SUPERFAMILY SSF52540 110 321 6.76E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 443 1.7E-187 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Gene3D G3DSA:1.10.8.60 275 346 2.4E-28 T 28-03-2018 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 444 35.061 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 SMART SM00760 353 422 1.5E-40 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 355 422 2.4E-30 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 SUPERFAMILY SSF48295 340 445 6.28E-37 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 Gene3D G3DSA:1.10.1750.10 347 444 1.4E-35 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A21D_RS07230 19a5b979fe99750ff6511eb60197495c 446 ProSitePatterns PS01008 DnaA protein signature. 403 422 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 PIRSF PIRSF002401 1 377 4.2E-141 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Gene3D G3DSA:3.40.50.300 158 340 5.2E-32 T 28-03-2018 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Pfam PF01018 GTP1/OBG 3 157 1.1E-58 T 28-03-2018 IPR006169 GTP1/OBG domain A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 SUPERFAMILY SSF82051 1 157 2.62E-54 T 28-03-2018 IPR006169 GTP1/OBG domain A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.306 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 359 428 1.7E-28 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Pfam PF09269 Domain of unknown function (DUF1967) 359 427 1.9E-28 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Gene3D G3DSA:2.70.210.12 1 155 3.6E-57 T 28-03-2018 IPR006169 GTP1/OBG domain A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 SUPERFAMILY SSF102741 356 429 1.7E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 Pfam PF01926 50S ribosome-binding GTPase 160 283 2.2E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 8.6E-141 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 7.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 7.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 7.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 7.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15235 70a069949b72cb4bdf4209383e4c24a8 429 SUPERFAMILY SSF52540 151 332 3.19E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02715 d21e7067681a65798d437af45f460595 236 Gene3D G3DSA:3.40.1410.10 80 234 1.1E-20 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS02715 d21e7067681a65798d437af45f460595 236 SUPERFAMILY SSF64288 61 235 6.6E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS02715 d21e7067681a65798d437af45f460595 236 Pfam PF07702 UTRA domain 95 226 3.6E-16 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS02715 d21e7067681a65798d437af45f460595 236 SMART SM00345 14 73 3.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS02715 d21e7067681a65798d437af45f460595 236 SUPERFAMILY SSF46785 5 82 2.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02715 d21e7067681a65798d437af45f460595 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS02715 d21e7067681a65798d437af45f460595 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS02715 d21e7067681a65798d437af45f460595 236 Gene3D G3DSA:1.10.10.10 2 74 9.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02715 d21e7067681a65798d437af45f460595 236 SMART SM00866 94 229 7.2E-14 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS02715 d21e7067681a65798d437af45f460595 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 5.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS10265 2de51f856fa53b086d46e6f7985be8aa 243 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 4 110 1.5E-34 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family A21D_RS10265 2de51f856fa53b086d46e6f7985be8aa 243 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 14 106 3.3E-19 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family A21D_RS10265 2de51f856fa53b086d46e6f7985be8aa 243 Pfam PF10552 ORF6C domain 119 230 8.5E-35 T 28-03-2018 IPR018878 ORF6C domain A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Gene3D G3DSA:3.30.930.10 2 300 9.5E-74 T 28-03-2018 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 106 275 1.6E-19 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Gene3D G3DSA:3.40.50.800 301 409 6.2E-32 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Gene3D G3DSA:3.30.110.30 410 478 2.8E-24 T 28-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 SUPERFAMILY SSF55681 16 280 3.78E-81 T 28-03-2018 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 412 479 2.1E-23 T 28-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 SMART SM00946 412 479 3.6E-31 T 28-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.1E-9 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 PRINTS PR01046 Prolyl-tRNA synthetase signature 111 122 1.1E-9 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 149 1.1E-9 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 PRINTS PR01046 Prolyl-tRNA synthetase signature 150 161 1.1E-9 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 SUPERFAMILY SSF52954 283 404 3.11E-30 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Pfam PF03129 Anticodon binding domain 294 383 8.5E-17 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 Hamap MF_01571 Proline--tRNA ligase [proS]. 12 479 44.183 T 28-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 SUPERFAMILY SSF64586 408 479 1.43E-22 T 28-03-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS02930 9add1c786eb88708627096ad08c7a1d8 479 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 15 479 4.0E-183 T 28-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A21D_RS13385 d763e61975e575082c8318cbc0f249be 103 SUPERFAMILY SSF117916 1 100 2.29E-32 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS13385 d763e61975e575082c8318cbc0f249be 103 Gene3D G3DSA:3.30.300.130 2 101 4.6E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS13385 d763e61975e575082c8318cbc0f249be 103 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 1.6E-21 T 28-03-2018 IPR002744 MIP18 family-like A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 Gene3D G3DSA:3.50.50.60 95 132 0.098 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 SUPERFAMILY SSF51905 4 148 8.43E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 Gene3D G3DSA:3.50.50.60 9 94 4.9E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 Gene3D G3DSA:3.50.50.60 133 259 9.2E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 304 1.2E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02845 dea174d9c69fe5c73e62e606b31525a0 397 SUPERFAMILY SSF51905 119 259 1.32E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS12025 14bfa1918dc84880b780d3550da3793f 194 Pfam PF02630 SCO1/SenC 4 176 1.9E-42 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS12025 14bfa1918dc84880b780d3550da3793f 194 Gene3D G3DSA:3.40.30.10 20 192 1.1E-34 T 28-03-2018 A21D_RS12025 14bfa1918dc84880b780d3550da3793f 194 SUPERFAMILY SSF52833 31 192 3.96E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 SUPERFAMILY SSF46785 684 747 1.82E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 Gene3D G3DSA:1.10.10.10 685 739 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 SMART SM00382 427 609 7.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 Pfam PF09397 Ftsk gamma domain 686 745 6.5E-30 T 28-03-2018 IPR018541 FtsK gamma domain A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 Pfam PF01580 FtsK/SpoIIIE family 401 533 1.3E-46 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 Pfam PF01580 FtsK/SpoIIIE family 539 588 8.9E-16 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 SUPERFAMILY SSF52540 366 660 4.25E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 Gene3D G3DSA:3.40.50.300 292 628 1.2E-56 T 28-03-2018 A21D_RS17645 100984d38c9fb784c7cd067eee7a5939 756 SMART SM00843 683 748 2.0E-40 T 28-03-2018 IPR018541 FtsK gamma domain A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 PIRSF PIRSF500176 10 331 1.1E-84 T 28-03-2018 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 16 24 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 PRINTS PR00139 Asparaginase/glutaminase family signature 264 282 3.1E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 PRINTS PR00139 Asparaginase/glutaminase family signature 14 25 3.1E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 PRINTS PR00139 Asparaginase/glutaminase family signature 91 109 3.1E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 SMART SM00870 13 329 3.5E-101 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 Gene3D G3DSA:3.40.50.40 216 331 1.6E-23 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 Gene3D G3DSA:3.40.50.1170 9 215 4.5E-44 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 SUPERFAMILY SSF53774 9 322 2.88E-85 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 PIRSF PIRSF001220 8 332 1.3E-90 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A21D_RS16500 62b5b0a94fd2145fee1715d7aad238a2 332 Pfam PF00710 Asparaginase, N-terminal 13 203 6.3E-50 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A21D_RS10855 ab8ad79f3c75ae272366719e40d68c14 419 Pfam PF01882 Protein of unknown function DUF58 218 291 2.7E-15 T 28-03-2018 IPR002881 Domain of unknown function DUF58 A21D_RS10855 ab8ad79f3c75ae272366719e40d68c14 419 Gene3D G3DSA:3.40.50.410 226 378 0.0014 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS12315 e35f725b1d41bbdd5082d8e3682088ec 244 SMART SM00849 18 211 0.0017 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS12315 e35f725b1d41bbdd5082d8e3682088ec 244 Pfam PF12706 Beta-lactamase superfamily domain 29 212 1.6E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS12315 e35f725b1d41bbdd5082d8e3682088ec 244 Gene3D G3DSA:3.60.15.10 1 244 1.4E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS12315 e35f725b1d41bbdd5082d8e3682088ec 244 SUPERFAMILY SSF56281 1 244 6.29E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 423 5.3E-188 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 SUPERFAMILY SSF53383 8 423 1.14E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 Gene3D G3DSA:3.90.1150.10 291 438 1.4E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 423 1.0E-140 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A21D_RS09090 fece97e5187acc760291a67c758e41f0 583 Gene3D G3DSA:3.40.640.10 7 289 5.4E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 Pfam PF03315 Serine dehydratase beta chain 5 79 1.9E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 Gene3D G3DSA:3.30.70.260 148 219 5.7E-15 T 28-03-2018 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 Pfam PF01842 ACT domain 151 210 9.6E-10 T 28-03-2018 IPR002912 ACT domain A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 SUPERFAMILY SSF55021 137 216 3.78E-16 T 28-03-2018 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 PIRSF PIRSF036692 1 220 7.4E-103 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 Gene3D G3DSA:3.30.1330.90 20 145 8.6E-24 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 SUPERFAMILY SSF143548 19 137 1.07E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS08045 cdb199523ab358e6613e75ac7f90cd35 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 7.2E-83 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS17590 cd7503dac6c4ac1dc7d41ae2d785d1ed 303 Pfam PF13413 Helix-turn-helix domain 6 67 2.4E-22 T 28-03-2018 A21D_RS17590 cd7503dac6c4ac1dc7d41ae2d785d1ed 303 Pfam PF13464 Domain of unknown function (DUF4115) 221 291 9.4E-8 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 A21D_RS17590 cd7503dac6c4ac1dc7d41ae2d785d1ed 303 SUPERFAMILY SSF47413 1 74 8.59E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS17590 cd7503dac6c4ac1dc7d41ae2d785d1ed 303 Gene3D G3DSA:1.10.260.40 1 104 3.4E-14 T 28-03-2018 A21D_RS17590 cd7503dac6c4ac1dc7d41ae2d785d1ed 303 SMART SM00530 6 67 8.6E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS08730 b2150593b9664a6302319e091e91b651 200 SUPERFAMILY SSF52218 5 198 1.27E-47 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS08730 b2150593b9664a6302319e091e91b651 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 198 6.9E-46 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 A21D_RS08730 b2150593b9664a6302319e091e91b651 200 Pfam PF03358 NADPH-dependent FMN reductase 5 150 2.7E-19 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A21D_RS08730 b2150593b9664a6302319e091e91b651 200 Gene3D G3DSA:3.40.50.360 1 200 1.5E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 2.0E-90 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 SUPERFAMILY SSF55205 1 414 1.96E-131 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 1.2E-166 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 Gene3D G3DSA:3.65.10.10 218 418 2.7E-47 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 Gene3D G3DSA:3.65.10.10 21 217 3.4E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04680 2a7065f8bb9721333357afdf3ab2eb72 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 41.205 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS11945 70fdead4835bbd5b9066c25f17fc72fb 251 Gene3D G3DSA:3.40.50.150 5 248 1.2E-16 T 28-03-2018 A21D_RS11945 70fdead4835bbd5b9066c25f17fc72fb 251 SUPERFAMILY SSF53335 27 249 4.76E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS11945 70fdead4835bbd5b9066c25f17fc72fb 251 Pfam PF13649 Methyltransferase domain 40 135 4.1E-8 T 28-03-2018 A21D_RS00420 8f3b7f1237383a1e57ea02e1f48c46d4 392 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 218 386 3.0E-29 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A21D_RS00420 8f3b7f1237383a1e57ea02e1f48c46d4 392 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 388 7.8E-90 T 28-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A21D_RS07745 432402df00ece40d3d9b4f347ca64b16 177 SUPERFAMILY SSF53597 5 176 2.23E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS07745 432402df00ece40d3d9b4f347ca64b16 177 Gene3D G3DSA:3.40.430.10 2 176 2.6E-40 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A21D_RS07745 432402df00ece40d3d9b4f347ca64b16 177 Pfam PF01872 RibD C-terminal domain 6 166 6.3E-21 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A21D_RS19215 33a7c96943f48d692bac7a04854614ce 272 Pfam PF02535 ZIP Zinc transporter 120 267 1.3E-16 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A21D_RS04185 d4fe18a91c288afe89d2ece3bce70311 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 2.9E-57 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A21D_RS04185 d4fe18a91c288afe89d2ece3bce70311 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 231 4.3E-61 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A21D_RS04185 d4fe18a91c288afe89d2ece3bce70311 246 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 8 246 55.27 T 28-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A21D_RS04940 5b0a8ad8758561ebbc94adaf046cdea5 243 Pfam PF00005 ABC transporter 21 158 2.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04940 5b0a8ad8758561ebbc94adaf046cdea5 243 SMART SM00382 29 215 2.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04940 5b0a8ad8758561ebbc94adaf046cdea5 243 SUPERFAMILY SSF52540 3 220 2.8E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04940 5b0a8ad8758561ebbc94adaf046cdea5 243 Gene3D G3DSA:3.40.50.300 1 241 2.5E-57 T 28-03-2018 A21D_RS04940 5b0a8ad8758561ebbc94adaf046cdea5 243 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 Gene3D G3DSA:3.40.50.970 1 200 1.3E-65 T 28-03-2018 A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 SMART SM00861 5 192 2.7E-59 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 Pfam PF02780 Transketolase, C-terminal domain 206 328 2.7E-38 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 Gene3D G3DSA:3.40.50.920 201 342 1.3E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 SUPERFAMILY SSF52518 3 216 4.56E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 SUPERFAMILY SSF52922 201 336 5.23E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS19535 e3607012d65021c16af9a29f111f7648 343 Pfam PF02779 Transketolase, pyrimidine binding domain 4 192 9.3E-52 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Gene3D G3DSA:2.40.110.10 124 224 5.5E-29 T 28-03-2018 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 221 4.0E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 PIRSF PIRSF016578 7 368 3.8E-15 T 28-03-2018 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 380 3.1E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 SUPERFAMILY SSF56645 2 231 3.93E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 113 1.1E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Gene3D G3DSA:1.10.540.10 1 116 2.0E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 Gene3D G3DSA:1.20.140.10 225 386 1.4E-43 T 28-03-2018 A21D_RS04990 e5e85e58d539f8b7964082f3e6bfc143 386 SUPERFAMILY SSF47203 242 384 2.9E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS08710 6a40c9886f892db450772c6b756ed8d4 214 Pfam PF04397 LytTr DNA-binding domain 119 212 2.0E-26 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS08710 6a40c9886f892db450772c6b756ed8d4 214 Gene3D G3DSA:2.20.25.10 177 213 1.5E-11 T 28-03-2018 A21D_RS08710 6a40c9886f892db450772c6b756ed8d4 214 SMART SM00850 116 213 3.8E-29 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS08710 6a40c9886f892db450772c6b756ed8d4 214 Gene3D G3DSA:2.40.50.40 106 176 4.2E-20 T 28-03-2018 A21D_RS05660 0e018ed1b0fae3fe4204b631937c0380 244 Gene3D G3DSA:3.40.630.40 41 238 4.9E-58 T 28-03-2018 A21D_RS05660 0e018ed1b0fae3fe4204b631937c0380 244 SUPERFAMILY SSF53187 43 233 1.44E-52 T 28-03-2018 A21D_RS05660 0e018ed1b0fae3fe4204b631937c0380 244 SMART SM00646 119 230 2.1E-35 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS05660 0e018ed1b0fae3fe4204b631937c0380 244 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 46 230 3.3E-51 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS05660 0e018ed1b0fae3fe4204b631937c0380 244 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 44 232 3.3E-85 T 28-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SUPERFAMILY SSF89550 337 567 7.19E-55 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:3.30.210.10 248 316 1.3E-18 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Pfam PF14520 Helix-hairpin-helix domain 91 146 1.5E-7 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Pfam PF14716 Helix-hairpin-helix domain 6 71 5.3E-18 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:3.20.20.140 332 572 2.0E-47 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SUPERFAMILY SSF81301 154 316 2.42E-41 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SMART SM00483 2 316 2.9E-61 T 28-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SUPERFAMILY SSF47802 5 83 2.88E-18 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 PIRSF PIRSF005047 3 572 7.0E-236 T 28-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:3.30.460.10 154 246 3.2E-28 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SMART SM00278 125 144 4.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SMART SM00278 90 109 100.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SMART SM00278 50 69 740.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:1.10.150.20 98 152 6.8E-11 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:1.10.150.20 67 97 0.096 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Gene3D G3DSA:1.10.150.110 5 66 1.9E-17 T 28-03-2018 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 SMART SM00481 338 417 4.4E-16 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Pfam PF02811 PHP domain 339 524 5.2E-9 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS14770 6d087b0a0c391c2184bfc3cc9f1024a6 572 Pfam PF14791 DNA polymerase beta thumb 255 316 1.2E-18 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Gene3D G3DSA:3.40.50.980 176 333 4.3E-39 T 28-03-2018 A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 SUPERFAMILY SSF56801 4 523 1.7E-148 T 28-03-2018 A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 28-03-2018 IPR020845 AMP-binding, conserved site A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Gene3D G3DSA:3.30.300.30 422 524 6.9E-28 T 28-03-2018 A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Gene3D G3DSA:2.30.38.10 345 421 1.2E-20 T 28-03-2018 A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 511 2.2E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Gene3D G3DSA:3.40.50.980 6 175 1.8E-40 T 28-03-2018 A21D_RS12590 2245cccf7835de1b59b92400b376eca3 529 Pfam PF00501 AMP-binding enzyme 13 427 8.3E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SMART SM00825 Beta-ketoacyl synthase 34 464 9.3E-120 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Gene3D G3DSA:1.10.1200.10 1174 1245 2.1E-12 T 28-03-2018 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Gene3D G3DSA:3.40.50.720 681 825 0.12 T 28-03-2018 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 416 516 9.3E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 32 287 5.6E-59 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SUPERFAMILY SSF53901 28 401 3.38E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SUPERFAMILY SSF51735 881 1087 5.39E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Gene3D G3DSA:3.40.47.10 24 299 4.5E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Gene3D G3DSA:3.40.50.720 874 1173 4.5E-16 T 28-03-2018 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Pfam PF00550 Phosphopantetheine attachment site 1179 1239 2.8E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 885 1083 1.8E-6 T 28-03-2018 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 412 6.4E-33 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Pfam PF08659 KR domain 885 1080 4.9E-30 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SUPERFAMILY SSF47336 1172 1241 3.27E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 Gene3D G3DSA:3.40.47.10 300 462 3.5E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS11915 920e099d305d56762a38afb7fb9efb56 1278 SUPERFAMILY SSF51735 639 869 5.48E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11985 46d772115fd7bac91f5ea59fa109ddce 283 SUPERFAMILY SSF56300 56 279 8.52E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS11985 46d772115fd7bac91f5ea59fa109ddce 283 Gene3D G3DSA:3.60.21.10 54 281 5.6E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS11985 46d772115fd7bac91f5ea59fa109ddce 283 Pfam PF00149 Calcineurin-like phosphoesterase 57 217 1.0E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 1.7E-128 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 SUPERFAMILY SSF52540 1 217 3.1E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 SUPERFAMILY SSF52540 244 351 3.1E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 100.719 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 Gene3D G3DSA:3.40.50.300 1 369 1.2E-32 T 28-03-2018 A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 347 9.3E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A21D_RS07215 6e7445d3ac9345e386bf0e3259d944d5 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A21D_RS12545 3dad5f7363e4f920bf61acb9d35301b7 382 Gene3D G3DSA:3.40.50.10540 1 380 2.5E-133 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS12545 3dad5f7363e4f920bf61acb9d35301b7 382 Pfam PF02515 CoA-transferase family III 4 370 6.9E-124 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 A21D_RS12545 3dad5f7363e4f920bf61acb9d35301b7 382 SUPERFAMILY SSF89796 2 375 4.84E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS16740 8c75024c5db47b26ab0c4fa8d87e521e 177 SUPERFAMILY SSF54403 48 103 2.64E-7 T 28-03-2018 A21D_RS16740 8c75024c5db47b26ab0c4fa8d87e521e 177 SUPERFAMILY SSF54403 111 169 5.1E-11 T 28-03-2018 A21D_RS16740 8c75024c5db47b26ab0c4fa8d87e521e 177 Gene3D G3DSA:3.10.450.40 111 171 4.8E-5 T 28-03-2018 A21D_RS16740 8c75024c5db47b26ab0c4fa8d87e521e 177 Gene3D G3DSA:3.10.450.40 41 105 1.4E-11 T 28-03-2018 A21D_RS16695 af77deb09d9250ac5f5b238718b4a034 289 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 2.2E-24 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS16695 af77deb09d9250ac5f5b238718b4a034 289 PIRSF PIRSF006483 2 283 1.6E-91 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS16695 af77deb09d9250ac5f5b238718b4a034 289 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 215 3.3E-62 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS09045 3764d0b61c4b18923618287499d93527 247 Pfam PF12698 ABC-2 family transporter protein 54 239 4.4E-19 T 28-03-2018 A21D_RS09045 3764d0b61c4b18923618287499d93527 247 PIRSF PIRSF006648 3 245 2.2E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS06780 3037f0e4240dcd50160ad6a17bec9d4d 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 1.5E-6 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A21D_RS06780 3037f0e4240dcd50160ad6a17bec9d4d 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PRINTS PR01009 Flagellar M-ring protein signature 154 168 6.1E-20 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PRINTS PR01009 Flagellar M-ring protein signature 122 140 6.1E-20 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PRINTS PR01009 Flagellar M-ring protein signature 198 216 6.1E-20 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PRINTS PR01009 Flagellar M-ring protein signature 348 372 6.1E-20 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PRINTS PR01009 Flagellar M-ring protein signature 270 288 6.1E-20 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 Pfam PF01514 Secretory protein of YscJ/FliF family 33 219 4.1E-56 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 531 2.8E-118 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 Gene3D G3DSA:1.20.5.510 435 474 3.8E-5 T 28-03-2018 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 PIRSF PIRSF004862 1 532 9.2E-99 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 Gene3D G3DSA:3.30.70.1530 52 115 1.3E-5 T 28-03-2018 A21D_RS17945 0302ba8cb3d7183439c63404f99f083a 532 Pfam PF08345 Flagellar M-ring protein C-terminal 257 398 3.0E-20 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 SUPERFAMILY SSF81799 113 214 4.05E-35 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 SUPERFAMILY SSF53335 4 112 1.9E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 SUPERFAMILY SSF53335 214 310 1.9E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 1.2E-116 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 Gene3D G3DSA:1.10.150.170 111 216 5.1E-39 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 Pfam PF01795 MraW methylase family 2 309 1.7E-126 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 PIRSF PIRSF004486 1 311 9.9E-111 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS18425 0bdc28901e080be2f817ec7c5b01c4a8 325 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 37.517 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS17370 c578b1df422ef72e936068000e10d454 100 Gene3D G3DSA:1.10.287.1080 2 100 1.1E-20 T 28-03-2018 A21D_RS17370 c578b1df422ef72e936068000e10d454 100 SUPERFAMILY SSF101386 5 91 2.94E-15 T 28-03-2018 A21D_RS17370 c578b1df422ef72e936068000e10d454 100 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 92 8.3E-8 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 Pfam PF03466 LysR substrate binding domain 91 294 2.1E-39 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 SUPERFAMILY SSF53850 91 296 1.09E-36 T 28-03-2018 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 Gene3D G3DSA:3.40.190.10 187 260 1.9E-13 T 28-03-2018 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 Gene3D G3DSA:1.10.10.10 1 83 9.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 Gene3D G3DSA:3.40.190.10 90 186 1.3E-17 T 28-03-2018 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.6E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS12135 ae6431a9d160707d9c84d9b701a5507f 311 SUPERFAMILY SSF46785 2 111 4.24E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.561 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 9.3E-52 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.3E-33 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 SUPERFAMILY SSF46946 2 114 5.76E-44 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 Gene3D G3DSA:1.10.8.50 1 66 3.2E-26 T 28-03-2018 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 Gene3D G3DSA:4.10.910.10 67 85 6.9E-18 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 PIRSF PIRSF002134 1 121 3.3E-42 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06250 9f1cdbab10b2d142d9e66d6167f9d5fd 121 Gene3D G3DSA:4.10.910.10 86 121 5.5E-25 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 389 7.2E-84 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 SUPERFAMILY SSF144010 357 395 1.57E-48 T 28-03-2018 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 SUPERFAMILY SSF144010 153 198 1.57E-48 T 28-03-2018 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 SUPERFAMILY SSF144010 237 329 1.57E-48 T 28-03-2018 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 SUPERFAMILY SSF144010 6 76 1.57E-48 T 28-03-2018 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 Gene3D G3DSA:3.30.1330.100 6 151 1.9E-23 T 28-03-2018 A21D_RS07730 02cba3193fc8ebdb93066975f698c681 396 Gene3D G3DSA:3.30.1330.100 166 396 1.2E-17 T 28-03-2018 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PIRSF PIRSF000724 1 393 2.1E-156 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 345 356 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 PRINTS PR00477 Phosphoglycerate kinase family signature 368 385 6.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 392 42.908 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 Gene3D G3DSA:3.40.50.1260 179 380 3.4E-91 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 Pfam PF00162 Phosphoglycerate kinase 6 382 1.4E-165 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 SUPERFAMILY SSF53748 1 392 3.18E-161 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS00520 3c9b32b77a4b39e126bfa42d4d8803c3 393 Gene3D G3DSA:3.40.50.1260 3 178 3.0E-73 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 Gene3D G3DSA:3.40.309.10 268 463 6.8E-75 T 28-03-2018 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 SUPERFAMILY SSF53720 4 482 1.96E-168 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 Gene3D G3DSA:3.40.605.10 3 267 9.6E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 Pfam PF00171 Aldehyde dehydrogenase family 12 477 1.7E-177 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS10765 37ca23ad8de62f45a5d9768d08873dea 489 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 7 475 2.3E-213 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 A21D_RS11625 7e43ae941c06ec2d91bc1252e922b88b 59 SUPERFAMILY SSF47598 2 49 2.45E-11 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 A21D_RS11625 7e43ae941c06ec2d91bc1252e922b88b 59 Gene3D G3DSA:1.10.1220.10 4 44 6.3E-15 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 Pfam PF00245 Alkaline phosphatase 45 455 6.3E-114 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 Gene3D G3DSA:3.40.720.10 24 466 2.2E-135 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 SUPERFAMILY SSF53649 30 457 6.41E-129 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 ProSitePatterns PS00123 Alkaline phosphatase active site. 97 105 - T 28-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 PRINTS PR00113 Alkaline phosphatase signature 45 65 1.0E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 PRINTS PR00113 Alkaline phosphatase signature 188 198 1.0E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 PRINTS PR00113 Alkaline phosphatase signature 97 112 1.0E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 PRINTS PR00113 Alkaline phosphatase signature 143 163 1.0E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 PRINTS PR00113 Alkaline phosphatase signature 263 292 1.0E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS02130 08da50f7f28f3e3a6319a7b2fa4b0760 548 SMART SM00098 46 459 1.8E-129 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 Gene3D G3DSA:2.60.120.280 6 159 2.1E-24 T 28-03-2018 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 Gene3D G3DSA:1.10.10.60 168 222 4.6E-12 T 28-03-2018 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 Pfam PF02311 AraC-like ligand binding domain 26 144 7.2E-12 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 SUPERFAMILY SSF51215 14 156 8.24E-22 T 28-03-2018 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 SUPERFAMILY SSF46689 224 275 4.93E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 Gene3D G3DSA:1.10.10.60 223 278 4.7E-14 T 28-03-2018 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 Pfam PF12833 Helix-turn-helix domain 194 272 4.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 SUPERFAMILY SSF46689 176 222 3.58E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 SMART SM00342 188 271 2.2E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 271 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS01390 64655e08166cc94a275ab068de306fad 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 255 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 285 3.6E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 SUPERFAMILY SSF51905 1 300 3.03E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 Gene3D G3DSA:3.50.50.60 1 123 4.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 Gene3D G3DSA:3.50.50.60 156 318 5.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.3E-7 T 28-03-2018 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 6.3E-7 T 28-03-2018 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 6.3E-7 T 28-03-2018 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 Gene3D G3DSA:3.50.50.60 124 155 0.36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.5E-8 T 28-03-2018 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 1.5E-8 T 28-03-2018 A21D_RS08700 487d9b04e84013eadc034e2c4e90fafd 353 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 1.5E-8 T 28-03-2018 A21D_RS08120 d5ec1d03cfe83bfdd5f2400fb4948f69 272 Pfam PF01226 Formate/nitrite transporter 7 251 1.3E-65 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 A21D_RS08120 d5ec1d03cfe83bfdd5f2400fb4948f69 272 Gene3D G3DSA:1.20.1080.10 1 265 7.1E-73 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A21D_RS08120 d5ec1d03cfe83bfdd5f2400fb4948f69 272 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 160 170 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site A21D_RS08120 d5ec1d03cfe83bfdd5f2400fb4948f69 272 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 32.762 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 Gene3D G3DSA:3.40.1390.20 3 132 2.1E-42 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 Gene3D G3DSA:3.40.50.300 135 307 5.2E-32 T 28-03-2018 A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 Pfam PF02603 HPr Serine kinase N terminus 4 126 7.7E-38 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 SUPERFAMILY SSF53795 133 299 6.1E-31 T 28-03-2018 A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 4 302 1.9E-99 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 SUPERFAMILY SSF75138 3 127 6.02E-35 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A21D_RS04325 c86cfd418bbb827a80ae447dce30b7af 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 1.2E-58 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 SUPERFAMILY SSF54211 1 228 8.35E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 3 354 2.2E-99 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 Gene3D G3DSA:3.30.70.890 219 350 3.1E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 Gene3D G3DSA:3.30.230.10 1 218 1.8E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 SUPERFAMILY SSF55060 213 352 3.12E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 Pfam PF00288 GHMP kinases N terminal domain 99 170 1.7E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 Pfam PF08544 GHMP kinases C terminal 264 344 4.3E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 PRINTS PR00959 Mevalonate kinase family signature 311 328 9.2E-6 T 28-03-2018 A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 PRINTS PR00959 Mevalonate kinase family signature 107 129 9.2E-6 T 28-03-2018 A21D_RS05365 20879176d8571ea3aa693b6308dd12de 369 PRINTS PR00959 Mevalonate kinase family signature 5 29 9.2E-6 T 28-03-2018 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 163 9.1E-17 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 Gene3D G3DSA:3.40.47.10 1 166 3.1E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 2.5E-166 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 Gene3D G3DSA:3.40.47.10 175 319 9.0E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 SUPERFAMILY SSF53901 168 386 7.09E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 256 350 1.9E-13 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 A21D_RS19330 e513c24decfbc881dc6689b8bfae9754 393 SUPERFAMILY SSF53901 2 166 1.42E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 PIRSF PIRSF000386 1 239 4.9E-108 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 2.6E-102 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 110.821 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 3.7E-75 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 Gene3D G3DSA:3.40.1280.10 1 169 1.3E-78 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 Gene3D G3DSA:1.10.1270.20 170 239 1.1E-33 T 28-03-2018 A21D_RS18040 703f826b8d80357e0b94f6967c3865e7 239 SUPERFAMILY SSF75217 1 236 2.16E-101 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS10995 5453b6f1d87aec45f93e893a734b5102 228 SUPERFAMILY SSF51395 7 222 1.32E-43 T 28-03-2018 A21D_RS10995 5453b6f1d87aec45f93e893a734b5102 228 Pfam PF01884 PcrB family 6 226 2.8E-72 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A21D_RS10995 5453b6f1d87aec45f93e893a734b5102 228 Gene3D G3DSA:3.20.20.390 1 224 3.1E-23 T 28-03-2018 A21D_RS10995 5453b6f1d87aec45f93e893a734b5102 228 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 10 223 2.3E-64 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A21D_RS10995 5453b6f1d87aec45f93e893a734b5102 228 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 4 226 27.075 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A21D_RS05355 a7fbcb52c625b3f63ccda65d1d912021 233 SUPERFAMILY SSF51658 8 222 5.37E-26 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS05355 a7fbcb52c625b3f63ccda65d1d912021 233 Pfam PF01261 Xylose isomerase-like TIM barrel 10 183 5.1E-13 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS05355 a7fbcb52c625b3f63ccda65d1d912021 233 Gene3D G3DSA:3.20.20.150 1 226 2.4E-27 T 28-03-2018 A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 309 9.9E-12 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 2.7E-64 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 Gene3D G3DSA:3.40.50.720 113 284 3.5E-57 T 28-03-2018 A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 SUPERFAMILY SSF52283 9 123 7.65E-15 T 28-03-2018 A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 SUPERFAMILY SSF51735 101 282 2.79E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08110 2d5bc29c1f33625f5d95a1e4c368f1a6 320 Gene3D G3DSA:3.40.50.720 3 112 4.1E-22 T 28-03-2018 A21D_RS02235 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS02235 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS02235 423258b5619abed75468efd0a225b439 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS02235 423258b5619abed75468efd0a225b439 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS13260 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS13260 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS13260 423258b5619abed75468efd0a225b439 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS13260 423258b5619abed75468efd0a225b439 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18615 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18615 423258b5619abed75468efd0a225b439 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS18615 423258b5619abed75468efd0a225b439 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS18615 423258b5619abed75468efd0a225b439 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18245 3ace1cf300f640d6eae442abc09b0611 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 135 3.2E-51 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A21D_RS18245 3ace1cf300f640d6eae442abc09b0611 139 Gene3D G3DSA:3.30.300.20 44 138 7.1E-25 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS18245 3ace1cf300f640d6eae442abc09b0611 139 Pfam PF02566 OsmC-like protein 39 134 7.6E-18 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS18245 3ace1cf300f640d6eae442abc09b0611 139 Gene3D G3DSA:2.20.25.10 1 43 4.3E-12 T 28-03-2018 A21D_RS18245 3ace1cf300f640d6eae442abc09b0611 139 SUPERFAMILY SSF82784 5 135 9.16E-36 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 Gene3D G3DSA:1.20.1250.20 12 203 1.2E-28 T 28-03-2018 A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 SUPERFAMILY SSF103473 257 426 2.35E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 SUPERFAMILY SSF103473 9 201 2.35E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 Gene3D G3DSA:1.20.1250.20 269 433 1.9E-25 T 28-03-2018 A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 Pfam PF07690 Major Facilitator Superfamily 24 417 2.8E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 4.6E-8 T 28-03-2018 A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 83 105 4.6E-8 T 28-03-2018 A21D_RS03400 fecc242be1c578a494c948e011894a5d 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 4.6E-8 T 28-03-2018 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 331 350 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 373 2.1E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 212 4.2E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Gene3D G3DSA:2.40.110.10 120 212 3.0E-37 T 28-03-2018 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Gene3D G3DSA:1.10.540.10 1 119 5.1E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 SUPERFAMILY SSF56645 4 235 4.06E-85 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 PIRSF PIRSF016578 4 374 1.3E-21 T 28-03-2018 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 SUPERFAMILY SSF47203 222 374 8.86E-61 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 117 1.4E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS04720 2e171bb5e0db7be619f9e6a5c53f13a7 375 Gene3D G3DSA:1.20.140.10 213 375 1.3E-62 T 28-03-2018 A21D_RS12470 9547746d6476344d7752223d5df7e247 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 229 8.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12470 9547746d6476344d7752223d5df7e247 254 SUPERFAMILY SSF161098 51 234 1.57E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12470 9547746d6476344d7752223d5df7e247 254 Gene3D G3DSA:1.10.3720.10 5 248 1.6E-27 T 28-03-2018 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 2 297 59.012 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Gene3D G3DSA:1.10.150.130 3 111 1.1E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Pfam PF00589 Phage integrase family 112 283 2.7E-54 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 4 297 58.21 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 SUPERFAMILY SSF56349 4 289 4.71E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 8 297 6.3E-118 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Gene3D G3DSA:1.10.443.10 112 291 1.4E-51 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 90 1.1E-22 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A21D_RS16315 f5f08cb093fe2331a090a94bbbe7a142 297 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 297 8.6E-102 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 Gene3D G3DSA:1.10.3140.10 3 143 4.4E-45 T 28-03-2018 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 478 3.2E-67 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 3 479 8.3E-244 T 28-03-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 Gene3D G3DSA:2.40.110.10 144 274 4.9E-16 T 28-03-2018 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 PIRSF PIRSF000331 1 483 1.1E-172 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 Gene3D G3DSA:1.20.140.10 283 479 2.1E-70 T 28-03-2018 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 SUPERFAMILY SSF47203 263 479 7.11E-60 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 SUPERFAMILY SSF56645 4 272 1.42E-72 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS19400 fbe2eec73aee01b5dac0424a21796431 483 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 272 4.6E-92 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal A21D_RS18910 776a1034720f1235e30e79bdeb7bccf3 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS18910 776a1034720f1235e30e79bdeb7bccf3 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS18910 776a1034720f1235e30e79bdeb7bccf3 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 7.1E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS18910 776a1034720f1235e30e79bdeb7bccf3 409 SUPERFAMILY SSF53098 62 342 3.64E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 Pfam PF05343 M42 glutamyl aminopeptidase 46 333 5.8E-74 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 SUPERFAMILY SSF53187 169 338 2.92E-58 T 28-03-2018 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 SUPERFAMILY SSF53187 7 82 2.92E-58 T 28-03-2018 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 SUPERFAMILY SSF101821 72 174 6.26E-20 T 28-03-2018 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 PIRSF PIRSF001123 2 349 2.8E-85 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 Gene3D G3DSA:2.40.30.40 71 156 1.1E-18 T 28-03-2018 IPR023367 Peptidase M42, domain 2 A21D_RS14035 14287781c230719f83bb67dfff64ccb5 352 Gene3D G3DSA:3.40.630.10 157 351 6.6E-38 T 28-03-2018 A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 Gene3D G3DSA:3.40.50.720 1 44 5.6E-8 T 28-03-2018 A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 Gene3D G3DSA:3.40.50.720 45 241 1.4E-66 T 28-03-2018 A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 239 6.8E-62 T 28-03-2018 A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 SUPERFAMILY SSF51735 5 239 8.23E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS09220 01687b8122bb2745d174338ea2a7fe2a 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 184 0.0013 T 28-03-2018 A21D_RS08495 0724ade0081ca9ded9ee476a1882f733 185 Pfam PF01380 SIS domain 31 133 1.9E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS08495 0724ade0081ca9ded9ee476a1882f733 185 SUPERFAMILY SSF53697 1 167 2.02E-33 T 28-03-2018 A21D_RS08495 0724ade0081ca9ded9ee476a1882f733 185 Gene3D G3DSA:3.40.50.10490 1 185 1.7E-34 T 28-03-2018 A21D_RS08495 0724ade0081ca9ded9ee476a1882f733 185 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 6 185 6.9E-64 T 28-03-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Gene3D G3DSA:3.40.50.10490 239 427 1.1E-54 T 28-03-2018 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 SUPERFAMILY SSF53697 244 600 4.82E-95 T 28-03-2018 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Pfam PF13522 Glutamine amidotransferase domain 57 191 6.3E-22 T 28-03-2018 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Gene3D G3DSA:3.60.20.10 2 238 7.3E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 2.4E-227 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 SUPERFAMILY SSF56235 2 234 5.15E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Gene3D G3DSA:3.40.50.10490 442 598 2.8E-43 T 28-03-2018 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.511 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Pfam PF01380 SIS domain 288 414 5.1E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS05225 b64034bd6f974e48eb3430ba0e1a6829 600 Pfam PF01380 SIS domain 457 582 6.2E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS05770 5325d965f81b165c912ab633ea146bba 333 SMART SM00382 26 210 8.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05770 5325d965f81b165c912ab633ea146bba 333 Gene3D G3DSA:3.40.50.300 1 264 4.2E-74 T 28-03-2018 A21D_RS05770 5325d965f81b165c912ab633ea146bba 333 SUPERFAMILY SSF52540 1 239 5.46E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05770 5325d965f81b165c912ab633ea146bba 333 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05770 5325d965f81b165c912ab633ea146bba 333 Pfam PF00005 ABC transporter 18 160 6.4E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 SUPERFAMILY SSF56601 308 674 6.24E-65 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 Gene3D G3DSA:3.90.1310.10 26 307 5.8E-37 T 28-03-2018 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 Pfam PF00905 Penicillin binding protein transpeptidase domain 342 669 2.5E-65 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 291 2.8E-38 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 Gene3D G3DSA:3.40.710.10 308 686 6.2E-78 T 28-03-2018 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 SUPERFAMILY SSF56519 54 115 5.89E-38 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS15860 e179bad145353c70d71da24d66d1828c 688 SUPERFAMILY SSF56519 176 307 5.89E-38 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS10775 8683ad04d485e3e3e5be1fcf153bc417 299 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 43 286 6.5E-62 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS10775 8683ad04d485e3e3e5be1fcf153bc417 299 Gene3D G3DSA:3.40.190.10 35 137 1.5E-19 T 28-03-2018 A21D_RS10775 8683ad04d485e3e3e5be1fcf153bc417 299 SUPERFAMILY SSF53850 40 297 5.98E-74 T 28-03-2018 A21D_RS10775 8683ad04d485e3e3e5be1fcf153bc417 299 Gene3D G3DSA:3.40.190.100 138 248 9.2E-39 T 28-03-2018 A21D_RS06295 7d7ae8937dd9f3c24c1b9c3b52d5a9f3 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 121 2.9E-48 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06295 7d7ae8937dd9f3c24c1b9c3b52d5a9f3 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 121 29.733 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06295 7d7ae8937dd9f3c24c1b9c3b52d5a9f3 121 Gene3D G3DSA:3.30.420.100 2 121 9.5E-43 T 28-03-2018 A21D_RS06295 7d7ae8937dd9f3c24c1b9c3b52d5a9f3 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 121 9.9E-43 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06295 7d7ae8937dd9f3c24c1b9c3b52d5a9f3 121 SUPERFAMILY SSF53137 7 119 8.72E-51 T 28-03-2018 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 Pfam PF01235 Sodium:alanine symporter family 59 450 2.6E-158 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 93 115 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 347 369 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 183 201 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 211 230 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 407 427 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 PRINTS PR00175 Sodium/alanine symporter signature 302 320 1.1E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09110 461c65964fac2ed215989dd0beb9cd7a 473 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 1.6E-155 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 3.3E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 SMART SM00836 437 555 9.8E-51 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 SMART SM01016 5 96 3.8E-34 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Gene3D G3DSA:3.40.50.620 114 367 5.3E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Pfam PF05746 DALR anticodon binding domain 437 555 1.2E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Gene3D G3DSA:3.30.1360.70 3 113 2.3E-30 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Gene3D G3DSA:1.10.730.10 403 555 3.0E-48 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 555 1.1E-161 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 555 27.236 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 96 4.0E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 Pfam PF00750 tRNA synthetases class I (R) 105 410 3.9E-26 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 SUPERFAMILY SSF52374 120 447 7.04E-92 T 28-03-2018 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 SUPERFAMILY SSF47323 431 555 1.31E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02085 f9a01068183b4e9be15e9321b0afa483 555 SUPERFAMILY SSF55190 6 116 3.53E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 SUPERFAMILY SSF50331 237 364 1.17E-27 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 SMART SM00382 29 217 1.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 SUPERFAMILY SSF52540 4 243 4.34E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 Gene3D G3DSA:2.40.50.140 294 349 1.0E-12 T 28-03-2018 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 Pfam PF03459 TOBE domain 297 355 2.0E-5 T 28-03-2018 IPR005116 Transport-associated OB, type 1 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 Pfam PF00005 ABC transporter 21 162 4.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 Gene3D G3DSA:3.40.50.300 1 235 2.2E-70 T 28-03-2018 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 Gene3D G3DSA:2.40.50.100 240 293 1.7E-14 T 28-03-2018 A21D_RS13005 294e4ce4d900e0593034389836f9b42c 365 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02660 47326c0375642f5510973898865ce97b 609 Pfam PF13727 CoA-binding domain 66 236 8.1E-17 T 28-03-2018 A21D_RS02660 47326c0375642f5510973898865ce97b 609 Pfam PF02719 Polysaccharide biosynthesis protein 281 564 2.9E-127 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A21D_RS02660 47326c0375642f5510973898865ce97b 609 Gene3D G3DSA:3.40.50.720 275 603 3.4E-62 T 28-03-2018 A21D_RS02660 47326c0375642f5510973898865ce97b 609 SUPERFAMILY SSF53335 103 308 1.45E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS02660 47326c0375642f5510973898865ce97b 609 SUPERFAMILY SSF51735 280 543 6.08E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02660 47326c0375642f5510973898865ce97b 609 Gene3D G3DSA:3.40.50.720 134 262 3.3E-27 T 28-03-2018 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Gene3D G3DSA:1.10.40.50 226 292 1.0E-22 T 28-03-2018 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 289 39.094 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Gene3D G3DSA:2.40.50.140 1 61 2.6E-24 T 28-03-2018 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 SUPERFAMILY SSF50249 1 62 5.14E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 282 2.5E-81 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Gene3D G3DSA:3.40.50.300 63 224 8.8E-23 T 28-03-2018 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Pfam PF16745 RsgA N-terminal domain 3 56 1.4E-23 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 Pfam PF03193 RsgA GTPase 59 224 3.3E-60 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A21D_RS18175 b5034d04ae9991f0a8364577490c631d 292 SUPERFAMILY SSF52540 64 290 4.65E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 793 6.5E-265 T 28-03-2018 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Gene3D G3DSA:1.10.268.10 343 485 4.4E-47 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Gene3D G3DSA:3.30.1360.40 235 331 1.4E-33 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 470 2.9E-152 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 804 32.914 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Gene3D G3DSA:2.120.10.90 499 816 6.8E-83 T 28-03-2018 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 SMART SM00434 10 463 1.6E-260 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 650 9.7E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 526 0.13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 654 696 1.1E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 755 5.1E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 598 1.6E-7 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 SUPERFAMILY SSF56719 30 485 1.44E-169 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 SUPERFAMILY SSF101904 499 808 2.09E-87 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 8 746 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS17045 05677085c5dcd0e29de6c9cc905f2227 817 Gene3D G3DSA:3.90.199.10 33 214 1.9E-77 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A21D_RS11365 4357291c10ac01b1e6d033cbb0e65762 75 Pfam PF01206 Sulfurtransferase TusA 5 74 1.5E-24 T 28-03-2018 IPR001455 TusA-like domain A21D_RS11365 4357291c10ac01b1e6d033cbb0e65762 75 SUPERFAMILY SSF64307 3 74 5.62E-26 T 28-03-2018 IPR001455 TusA-like domain A21D_RS11365 4357291c10ac01b1e6d033cbb0e65762 75 Gene3D G3DSA:3.30.110.40 1 75 8.1E-29 T 28-03-2018 IPR001455 TusA-like domain A21D_RS11365 4357291c10ac01b1e6d033cbb0e65762 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 28-03-2018 IPR001455 TusA-like domain A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 495 2.7E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 SUPERFAMILY SSF55604 436 509 1.83E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 449 466 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 Pfam PF02378 Phosphotransferase system, EIIC 13 351 1.1E-92 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 Pfam PF00367 phosphotransferase system, EIIB 438 469 1.5E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS04355 52442ed267bbd42db1a86e35e922cdfb 512 Gene3D G3DSA:3.30.1360.60 434 509 4.6E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS05830 c6516c44f11f6186ca9cc0d478a5ba55 256 Gene3D G3DSA:3.40.50.300 1 247 5.6E-55 T 28-03-2018 A21D_RS05830 c6516c44f11f6186ca9cc0d478a5ba55 256 Pfam PF00005 ABC transporter 19 165 1.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05830 c6516c44f11f6186ca9cc0d478a5ba55 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05830 c6516c44f11f6186ca9cc0d478a5ba55 256 SMART SM00382 26 215 6.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05830 c6516c44f11f6186ca9cc0d478a5ba55 256 SUPERFAMILY SSF52540 1 222 1.33E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02475 7f5d3ba3275bb784fd1bd5a547d4927e 79 SUPERFAMILY SSF47413 4 67 2.2E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS02475 7f5d3ba3275bb784fd1bd5a547d4927e 79 Pfam PF01381 Helix-turn-helix 8 58 1.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02475 7f5d3ba3275bb784fd1bd5a547d4927e 79 SMART SM00530 5 60 2.7E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02475 7f5d3ba3275bb784fd1bd5a547d4927e 79 Gene3D G3DSA:1.10.3100.10 1 79 1.3E-15 T 28-03-2018 IPR027910 YdiL-like domain A21D_RS03780 7433116a3c1eb540e9f869224020780e 317 Pfam PF01699 Sodium/calcium exchanger protein 176 314 2.2E-30 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A21D_RS03780 7433116a3c1eb540e9f869224020780e 317 Pfam PF01699 Sodium/calcium exchanger protein 2 150 1.8E-29 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A21D_RS03780 7433116a3c1eb540e9f869224020780e 317 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 4 309 8.0E-76 T 28-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 SUPERFAMILY SSF51905 158 337 2.38E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 SUPERFAMILY SSF51905 3 209 2.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 Gene3D G3DSA:3.50.50.60 1 93 4.6E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 Gene3D G3DSA:3.50.50.60 94 244 9.9E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 Gene3D G3DSA:3.50.50.60 266 350 9.5E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 323 9.1E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.3E-7 T 28-03-2018 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.3E-7 T 28-03-2018 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-7 T 28-03-2018 A21D_RS13945 ca1e9651a503865922112047d9b580aa 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 1.3E-7 T 28-03-2018 A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 109 1.5E-28 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 Gene3D G3DSA:3.30.230.10 1 114 1.4E-34 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 SUPERFAMILY SSF54211 1 112 6.07E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 101 2.0E-32 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.675 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A21D_RS07240 6949e97069585d7382c6ab0cda351765 114 Pfam PF00825 Ribonuclease P 1 107 3.2E-34 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A21D_RS12905 b3a5ed9888941ad4f3f2d1e4e5a33298 247 Pfam PF12791 Anti-sigma factor N-terminus 7 42 1.2E-5 T 28-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal A21D_RS02950 1c04f9dbfa9fb0a162d1c46ca91cf705 182 SUPERFAMILY SSF55166 39 162 2.01E-28 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS02950 1c04f9dbfa9fb0a162d1c46ca91cf705 182 Gene3D G3DSA:3.30.1380.10 25 162 5.2E-29 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS02950 1c04f9dbfa9fb0a162d1c46ca91cf705 182 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 91 162 1.9E-18 T 28-03-2018 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 Gene3D G3DSA:1.10.1740.10 7 86 5.3E-26 T 28-03-2018 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 SUPERFAMILY SSF88946 7 95 1.49E-29 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 Pfam PF04542 Sigma-70 region 2 27 89 3.5E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 Pfam PF08281 Sigma-70, region 4 129 180 1.4E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 SUPERFAMILY SSF88659 117 184 1.03E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 1.9E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 1.9E-93 T 28-03-2018 IPR014294 RNA polymerase sigma-W, bacillaceae A21D_RS05320 91f9579a7c1f2efd3d2f15f2ab2938a5 187 Gene3D G3DSA:1.10.10.10 87 187 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Gene3D G3DSA:2.60.200.20 84 182 3.4E-22 T 28-03-2018 A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Pfam PF01580 FtsK/SpoIIIE family 992 1183 1.8E-30 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Pfam PF01580 FtsK/SpoIIIE family 633 816 4.8E-28 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Pfam PF12538 DNA transporter 6 109 1.9E-16 T 28-03-2018 IPR022206 Firmicutes EssC, N-terminal A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 194 1484 0.0 T 28-03-2018 IPR023839 Firmicutes EssC, C-terminal A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 SUPERFAMILY SSF52540 950 1196 2.15E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Gene3D G3DSA:3.40.50.300 912 1205 1.9E-10 T 28-03-2018 A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 Gene3D G3DSA:3.40.50.300 278 861 9.2E-25 T 28-03-2018 A21D_RS19070 a883188f9ae482002525a6ddb49dedb2 1484 SUPERFAMILY SSF52540 630 885 6.18E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11630 521b6f8ccf9df5691e194339ead50a43 122 Gene3D G3DSA:1.10.287.100 83 118 1.7E-12 T 28-03-2018 A21D_RS11630 521b6f8ccf9df5691e194339ead50a43 122 SMART SM00345 15 74 4.7E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11630 521b6f8ccf9df5691e194339ead50a43 122 SUPERFAMILY SSF46785 5 82 6.87E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11630 521b6f8ccf9df5691e194339ead50a43 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 1.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS11630 521b6f8ccf9df5691e194339ead50a43 122 Gene3D G3DSA:1.10.10.10 11 82 8.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00820 a425526e5b81f0359df6e22282b3bdd0 133 PIRSF PIRSF039090 1 129 1.4E-35 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A21D_RS00820 a425526e5b81f0359df6e22282b3bdd0 133 Pfam PF02561 Flagellar protein FliS 8 118 2.0E-38 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A21D_RS00820 a425526e5b81f0359df6e22282b3bdd0 133 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 120 2.4E-37 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A21D_RS00820 a425526e5b81f0359df6e22282b3bdd0 133 SUPERFAMILY SSF101116 7 123 2.88E-37 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A21D_RS00820 a425526e5b81f0359df6e22282b3bdd0 133 Gene3D G3DSA:1.20.120.340 1 122 1.6E-39 T 28-03-2018 A21D_RS02010 e79b5e47891b58f4e4d52376cd4ad961 304 Pfam PF01261 Xylose isomerase-like TIM barrel 53 222 1.4E-21 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS02010 e79b5e47891b58f4e4d52376cd4ad961 304 Gene3D G3DSA:3.20.20.150 3 294 5.4E-47 T 28-03-2018 A21D_RS02010 e79b5e47891b58f4e4d52376cd4ad961 304 Hamap MF_01672 Inosose dehydratase [iolE]. 1 295 54.878 T 28-03-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 A21D_RS02010 e79b5e47891b58f4e4d52376cd4ad961 304 SUPERFAMILY SSF51658 7 292 3.18E-49 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS02010 e79b5e47891b58f4e4d52376cd4ad961 304 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 292 1.4E-115 T 28-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 155 3.1E-58 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 32.616 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 SUPERFAMILY SSF75217 3 155 3.66E-41 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 2.4E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 PIRSF PIRSF029256 2 156 1.6E-60 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A21D_RS12835 e1d3b702cbd172f826c1981115909f10 157 Gene3D G3DSA:3.40.1280.10 1 156 7.3E-40 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS19160 02102000ff6902a6f93fdea1583e8b9d 425 Gene3D G3DSA:1.20.1250.20 2 197 1.2E-15 T 28-03-2018 A21D_RS19160 02102000ff6902a6f93fdea1583e8b9d 425 Gene3D G3DSA:1.20.1250.20 215 417 5.1E-14 T 28-03-2018 A21D_RS19160 02102000ff6902a6f93fdea1583e8b9d 425 SUPERFAMILY SSF103473 20 409 8.37E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS19160 02102000ff6902a6f93fdea1583e8b9d 425 Pfam PF05977 Transmembrane secretion effector 14 404 1.5E-16 T 28-03-2018 IPR010290 Transmembrane secretion effector A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 152 3.7E-64 T 28-03-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 SUPERFAMILY SSF55811 21 111 2.44E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 Gene3D G3DSA:3.90.79.10 1 154 4.9E-22 T 28-03-2018 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 PRINTS PR00502 NUDIX hydrolase family signature 48 62 4.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 PRINTS PR00502 NUDIX hydrolase family signature 62 77 4.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS14125 bff7ace6692cadc7346e3626e9cc5420 155 Pfam PF00293 NUDIX domain 28 94 3.8E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS04620 ab371741922f90e1b0c24a0013cd5b2a 183 Pfam PF02659 Putative manganese efflux pump 34 181 1.7E-35 T 28-03-2018 IPR003810 Putative manganese efflux pump A21D_RS04620 ab371741922f90e1b0c24a0013cd5b2a 183 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 6 183 19.496 T 28-03-2018 IPR022929 Putative manganese efflux pump MntP A21D_RS00315 c5bbb5677d6b8a959f1ea609248a94b2 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 12 119 3.6E-22 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A21D_RS00315 c5bbb5677d6b8a959f1ea609248a94b2 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 124 16.174 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A21D_RS04505 13854fc53a581cba5c05bf39341cd276 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 7.6E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04505 13854fc53a581cba5c05bf39341cd276 311 SUPERFAMILY SSF161098 88 286 1.55E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04505 13854fc53a581cba5c05bf39341cd276 311 Gene3D G3DSA:1.10.3720.10 2 292 1.8E-43 T 28-03-2018 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Pfam PF06480 FtsH Extracellular 9 81 9.5E-7 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Gene3D G3DSA:3.40.50.300 140 345 1.9E-64 T 28-03-2018 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 616 38.638 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 331 2.2E-44 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Pfam PF01434 Peptidase family M41 393 601 2.1E-86 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 Gene3D G3DSA:1.10.8.60 346 407 5.5E-24 T 28-03-2018 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 SMART SM00382 195 334 4.5E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06660 26af6381348648ffa580980a182c07d9 687 ProSitePatterns PS00674 AAA-protein family signature. 302 320 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 SUPERFAMILY SSF52540 155 403 9.07E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06660 26af6381348648ffa580980a182c07d9 687 SUPERFAMILY SSF140990 413 610 3.66E-74 T 28-03-2018 A21D_RS06660 26af6381348648ffa580980a182c07d9 687 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 602 2.8E-245 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A21D_RS15720 953212501ad7b60117b43cc3552f6029 122 Pfam PF01219 Prokaryotic diacylglycerol kinase 14 114 7.7E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A21D_RS15720 953212501ad7b60117b43cc3552f6029 122 Gene3D G3DSA:1.10.3830.10 4 116 5.9E-38 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 Gene3D G3DSA:3.40.50.1100 38 141 4.6E-41 T 28-03-2018 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 Gene3D G3DSA:3.40.50.1100 142 306 3.8E-53 T 28-03-2018 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 1.9E-141 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 8.5E-134 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 SUPERFAMILY SSF53686 1 304 1.23E-100 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS06640 238c0f5a3a86e8cb58308e878cbaef3b 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 3.5E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS05970 fe71942d5dec8661115154d8abf443e3 367 SUPERFAMILY SSF56235 104 263 1.77E-9 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS05970 fe71942d5dec8661115154d8abf443e3 367 Gene3D G3DSA:3.60.60.10 91 358 6.2E-29 T 28-03-2018 A21D_RS05970 fe71942d5dec8661115154d8abf443e3 367 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 106 330 5.0E-38 T 28-03-2018 IPR005079 Peptidase C45 A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Hamap MF_01114 Regulatory protein RecX [recX]. 47 214 16.656 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Pfam PF02631 RecX family 89 209 3.6E-30 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Gene3D G3DSA:1.10.10.10 48 112 2.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Gene3D G3DSA:1.10.10.10 114 158 2.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Gene3D G3DSA:1.10.10.10 220 270 7.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11685 d5a59cb24dabbd46ef8f0cfcbba24aea 273 Gene3D G3DSA:1.10.10.10 163 211 1.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09980 50fa7f72333fa2bf6adbec47ee5b275d 159 Pfam PF03703 Bacterial PH domain 72 148 6.0E-17 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS01525 aa7cac8503caa86c0fb1ac917d101e43 159 Gene3D G3DSA:3.40.630.30 1 159 4.6E-34 T 28-03-2018 A21D_RS01525 aa7cac8503caa86c0fb1ac917d101e43 159 Pfam PF00583 Acetyltransferase (GNAT) family 52 136 4.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS01525 aa7cac8503caa86c0fb1ac917d101e43 159 SUPERFAMILY SSF55729 1 147 1.64E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 SUPERFAMILY SSF52540 243 393 1.13E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 SUPERFAMILY SSF52540 93 150 1.13E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 SUPERFAMILY SSF52540 2 202 1.54E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 Gene3D G3DSA:3.40.50.300 1 161 1.2E-12 T 28-03-2018 A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 Gene3D G3DSA:3.40.50.300 231 396 3.6E-17 T 28-03-2018 A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 SMART SM00490 279 358 0.0058 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS17405 2317bda893877c51b770b2c1d02ddbe9 399 Pfam PF00271 Helicase conserved C-terminal domain 260 358 1.1E-7 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS07865 e5b69baadb1fcfc9ee21b1fdd6c8e9a8 195 SUPERFAMILY SSF54518 61 155 8.37E-7 T 28-03-2018 IPR025659 Tubby C-terminal-like domain A21D_RS09770 035557621f29caad4f123f1449e677eb 375 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 218 359 9.0E-12 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 81 94 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 SUPERFAMILY SSF51735 148 352 6.29E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS09770 035557621f29caad4f123f1449e677eb 375 SMART SM00839 154 361 4.8E-28 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 139 161 1.0E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 182 202 1.0E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 297 308 1.0E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 73 87 1.0E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 Gene3D G3DSA:3.40.50.10860 10 153 3.1E-45 T 28-03-2018 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 20 137 1.2E-23 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 Gene3D G3DSA:3.40.50.720 154 350 2.3E-27 T 28-03-2018 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 SUPERFAMILY SSF53223 16 151 8.64E-44 T 28-03-2018 A21D_RS09770 035557621f29caad4f123f1449e677eb 375 PIRSF PIRSF000188 9 364 1.8E-147 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A21D_RS08445 6e41cbfc27662723c64373b656df669e 426 Gene3D G3DSA:3.40.50.2000 219 398 6.1E-16 T 28-03-2018 A21D_RS08445 6e41cbfc27662723c64373b656df669e 426 Pfam PF00534 Glycosyl transferases group 1 226 350 7.6E-14 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS08445 6e41cbfc27662723c64373b656df669e 426 SUPERFAMILY SSF53756 124 351 1.57E-21 T 28-03-2018 A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 Gene3D G3DSA:3.40.50.620 1 143 8.1E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 PIRSF PIRSF006276 1 143 5.6E-18 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 SUPERFAMILY SSF52402 3 143 2.23E-33 T 28-03-2018 A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 PRINTS PR01438 Universal stress protein signature 103 115 6.9E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 PRINTS PR01438 Universal stress protein signature 3 21 6.9E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 PRINTS PR01438 Universal stress protein signature 121 143 6.9E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS14460 cb639d1f0f7abb414065b4fada106223 143 Pfam PF00582 Universal stress protein family 3 143 5.8E-36 T 28-03-2018 IPR006016 UspA GO:0006950 A21D_RS18595 adaaa81324a59c97aa5d74e9a7b4a66a 67 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 2.9E-25 T 28-03-2018 IPR019241 Protein of unknown function DUF2197 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Gene3D G3DSA:3.90.550.10 1 240 2.6E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 SUPERFAMILY SSF51161 256 454 3.63E-49 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Pfam PF00483 Nucleotidyl transferase 6 213 6.8E-24 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Gene3D G3DSA:2.160.10.10 340 438 9.9E-20 T 28-03-2018 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.471 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 6.6E-183 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 SUPERFAMILY SSF53448 5 253 1.92E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 3.5E-10 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 256 283 0.0012 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 284 314 2.3E-4 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 3.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS06760 524577c8b40eeced797b5c679d87e45d 459 Gene3D G3DSA:2.160.10.10 241 339 1.0E-30 T 28-03-2018 A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 Gene3D G3DSA:3.40.50.300 1 250 3.2E-65 T 28-03-2018 A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 SMART SM00382 29 225 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 Pfam PF00005 ABC transporter 20 176 4.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 3 245 3.4E-109 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 A21D_RS08265 ac66aa6e3470b6e48e3e748ad5f19ea8 254 SUPERFAMILY SSF52540 3 242 8.35E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06520 0c8381938912b5fbeb927887e792ded5 182 Pfam PF02151 UvrB/uvrC motif 137 171 6.4E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS06520 0c8381938912b5fbeb927887e792ded5 182 PIRSF PIRSF015034 1 180 6.4E-64 T 28-03-2018 IPR025542 YacH protein A21D_RS06520 0c8381938912b5fbeb927887e792ded5 182 Gene3D G3DSA:4.10.860.10 113 172 6.5E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS06520 0c8381938912b5fbeb927887e792ded5 182 SUPERFAMILY SSF46600 137 171 3.66E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 SMART SM00382 28 246 5.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 SMART SM00382 356 522 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Gene3D G3DSA:1.20.58.410 581 642 7.6E-8 T 28-03-2018 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Gene3D G3DSA:3.40.50.300 4 295 3.6E-53 T 28-03-2018 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 SUPERFAMILY SSF52540 316 532 1.85E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Pfam PF16326 ABC transporter C-terminal domain 575 639 8.7E-11 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Gene3D G3DSA:3.40.50.300 329 580 3.0E-57 T 28-03-2018 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 SUPERFAMILY SSF52540 4 247 9.69E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Pfam PF12848 ABC transporter 233 318 4.7E-26 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 ProSitePatterns PS00211 ABC transporters family signature. 449 463 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Pfam PF00005 ABC transporter 19 194 9.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS10200 1d531367823cb2c1f74e4dd66e726f07 642 Pfam PF00005 ABC transporter 348 477 3.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05325 f306dbb0f0b538213c35f5ad7422b48a 59 Pfam PF09388 Spo0E like sporulation regulatory protein 2 34 2.4E-7 T 28-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A21D_RS05325 f306dbb0f0b538213c35f5ad7422b48a 59 SUPERFAMILY SSF140500 2 41 3.4E-7 T 28-03-2018 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 Gene3D G3DSA:3.40.50.300 238 535 1.9E-17 T 28-03-2018 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 SUPERFAMILY SSF52540 303 516 2.32E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 SUPERFAMILY SSF52540 3 50 2.32E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 Gene3D G3DSA:3.40.50.300 1 186 6.1E-27 T 28-03-2018 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 Pfam PF13476 AAA domain 5 217 1.1E-15 T 28-03-2018 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 561 5.4E-183 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 PIRSF PIRSF003128 1 566 2.4E-181 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A21D_RS16145 6ab33bc134a92b765e2d7ce532193f96 573 SUPERFAMILY SSF52540 1 221 7.97E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 PIRSF PIRSF000521 3 126 1.2E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 PIRSF PIRSF000521 118 424 1.5E-46 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 SUPERFAMILY SSF53383 19 421 6.66E-131 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 Pfam PF00202 Aminotransferase class-III 22 420 1.5E-126 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 Gene3D G3DSA:3.40.640.10 47 306 1.4E-84 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS02435 496c596bd8531384f24d73a1dba17a7b 427 Gene3D G3DSA:3.90.1150.10 307 425 8.5E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 Pfam PF00905 Penicillin binding protein transpeptidase domain 438 683 3.2E-28 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 SUPERFAMILY SSF56601 359 763 9.75E-97 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 SUPERFAMILY SSF56601 287 304 9.75E-97 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 Gene3D G3DSA:3.40.710.10 334 780 1.1E-90 T 28-03-2018 A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 SUPERFAMILY SSF53955 98 322 2.17E-63 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 Pfam PF00912 Transglycosylase 113 300 2.9E-57 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 Gene3D G3DSA:1.10.3810.10 103 317 2.2E-66 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS14375 f6dd9215806013ce1e01c9a78949d696 1014 Gene3D G3DSA:2.60.40.10 857 954 0.0059 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 PIRSF PIRSF002741 2 513 1.7E-119 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 SUPERFAMILY SSF53850 41 511 1.7E-127 T 28-03-2018 A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 Gene3D G3DSA:3.10.105.10 287 483 6.9E-48 T 28-03-2018 A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 435 8.0E-85 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 Gene3D G3DSA:3.90.76.10 68 159 4.4E-30 T 28-03-2018 A21D_RS12320 e497833a5a81932fa73e3b28f380d03c 513 Gene3D G3DSA:3.40.190.10 160 286 5.6E-31 T 28-03-2018 A21D_RS09440 b254756e7bb839e23c734f6974b91510 386 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 16 369 2.7E-114 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A21D_RS09440 b254756e7bb839e23c734f6974b91510 386 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 328 352 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A21D_RS09440 b254756e7bb839e23c734f6974b91510 386 Pfam PF01098 Cell cycle protein 19 370 7.0E-114 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A21D_RS02635 aef04887a550ee374851ce7bdeb0a1e7 389 Gene3D G3DSA:3.40.50.2000 174 382 4.8E-26 T 28-03-2018 A21D_RS02635 aef04887a550ee374851ce7bdeb0a1e7 389 SUPERFAMILY SSF53756 42 373 9.94E-36 T 28-03-2018 A21D_RS02635 aef04887a550ee374851ce7bdeb0a1e7 389 Pfam PF00534 Glycosyl transferases group 1 204 356 1.1E-20 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 Gene3D G3DSA:3.40.50.1980 23 185 1.2E-43 T 28-03-2018 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 275 294 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 34 52 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 78 95 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 244 262 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 191 212 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00690 Adhesin family signature 65 78 1.9E-41 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 308 1.3E-74 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 Gene3D G3DSA:3.40.50.1980 186 310 1.1E-39 T 28-03-2018 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 SUPERFAMILY SSF53807 34 310 1.67E-82 T 28-03-2018 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 191 208 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 267 285 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 34 55 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 288 306 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 59 77 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS08315 57c88e3fb4437adfc01d46a2bf26fef1 310 PRINTS PR00691 Adhesin B signature 78 97 7.5E-25 T 28-03-2018 IPR006129 Adhesin B GO:0007155 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Gene3D G3DSA:3.50.50.60 1 196 8.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Gene3D G3DSA:1.20.58.100 400 513 7.4E-18 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 SUPERFAMILY SSF56425 222 332 3.29E-27 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 SUPERFAMILY SSF51905 2 248 2.12E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 SUPERFAMILY SSF51905 336 392 2.12E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Gene3D G3DSA:3.90.700.10 229 314 2.0E-21 T 28-03-2018 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.9E-5 T 28-03-2018 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 357 3.9E-5 T 28-03-2018 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 492 4.3E-152 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Gene3D G3DSA:3.50.50.60 315 388 3.9E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 SUPERFAMILY SSF46977 414 517 1.14E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Pfam PF02910 Fumarate reductase flavoprotein C-term 415 517 1.2E-13 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS03450 ad3b2e25612e14c0d51f47b7dab502e4 527 Pfam PF00890 FAD binding domain 5 372 1.4E-68 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS08945 fda825696b453825595f99b9b5288ff0 622 Pfam PF02687 FtsX-like permease family 84 180 9.5E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS08945 fda825696b453825595f99b9b5288ff0 622 PIRSF PIRSF018968 375 620 1.5E-25 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A21D_RS08945 fda825696b453825595f99b9b5288ff0 622 PIRSF PIRSF018968 2 341 2.6E-35 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 SMART SM00257 191 234 1.9E-18 T 28-03-2018 IPR018392 LysM domain A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 SUPERFAMILY SSF53187 1 183 1.13E-42 T 28-03-2018 A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 Gene3D G3DSA:3.10.350.10 188 235 6.7E-20 T 28-03-2018 A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 Gene3D G3DSA:3.40.630.40 1 182 2.5E-41 T 28-03-2018 A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 Pfam PF01476 LysM domain 192 233 3.4E-17 T 28-03-2018 IPR018392 LysM domain A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 178 8.5E-32 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 SUPERFAMILY SSF54106 190 234 1.7E-13 T 28-03-2018 IPR018392 LysM domain A21D_RS05425 b74a4a9a34d81a0bd350e7ac24f1a533 306 SMART SM00646 66 178 2.0E-30 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 Gene3D G3DSA:3.20.20.10 40 284 3.8E-59 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 42 297 6.9E-65 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 SUPERFAMILY SSF50621 275 432 3.35E-50 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 82 99 2.0E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 399 421 2.0E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 317 335 2.0E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 2.0E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 Gene3D G3DSA:2.40.37.10 285 435 2.2E-40 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 84 96 2.0E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 389 402 2.0E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 288 307 2.0E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 2.0E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 82 2.0E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 20 432 38.777 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 431 5.7E-146 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 64 82 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 389 1.8E-15 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A21D_RS16370 5f45cf921d168dc61f9ba30bc406e17b 435 SUPERFAMILY SSF51419 31 300 4.65E-77 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 Gene3D G3DSA:1.20.1560.10 1 320 2.9E-67 T 28-03-2018 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 Pfam PF00664 ABC transporter transmembrane region 20 286 5.5E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 Pfam PF00005 ABC transporter 350 499 1.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 SUPERFAMILY SSF90123 3 316 5.89E-79 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 SMART SM00382 359 545 4.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 Gene3D G3DSA:3.40.50.300 321 571 3.8E-77 T 28-03-2018 A21D_RS07415 bb0ef3c9b23b471a0059ac72838fadb7 571 SUPERFAMILY SSF52540 324 570 4.28E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 28-03-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 SUPERFAMILY SSF51569 2 250 2.01E-72 T 28-03-2018 A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 17 245 1.7E-65 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 17 249 34.777 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 Pfam PF01487 Type I 3-dehydroquinase 20 246 2.2E-67 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A21D_RS00555 3c3a70b2a85f6a55e25c8124f1cd7477 254 Gene3D G3DSA:3.20.20.70 1 252 1.7E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS02215 b57324c3786937be28af78b2f82f4f28 331 Gene3D G3DSA:3.30.572.10 7 285 4.1E-37 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS02215 b57324c3786937be28af78b2f82f4f28 331 SUPERFAMILY SSF55831 3 256 1.06E-49 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS02215 b57324c3786937be28af78b2f82f4f28 331 Pfam PF00303 Thymidylate synthase 9 219 1.8E-19 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 482 726 1.5E-66 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 PRINTS PR01755 Bacterial translocase SecF protein signature 638 656 5.5E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 PRINTS PR01755 Bacterial translocase SecF protein signature 590 604 5.5E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 PRINTS PR01755 Bacterial translocase SecF protein signature 480 495 5.5E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 PRINTS PR01755 Bacterial translocase SecF protein signature 674 689 5.5E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Gene3D G3DSA:1.20.1640.10 203 418 9.5E-29 T 28-03-2018 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 426 32.126 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 SUPERFAMILY SSF82866 562 739 2.49E-38 T 28-03-2018 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Gene3D G3DSA:1.20.1640.10 517 746 1.7E-31 T 28-03-2018 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 201 405 2.4E-56 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 560 723 7.2E-50 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Pfam PF07549 SecD/SecF GG Motif 32 49 0.1 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Pfam PF07549 SecD/SecF GG Motif 475 500 3.7E-5 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 453 737 25.766 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Pfam PF02355 Protein export membrane protein 249 415 3.0E-14 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 Pfam PF02355 Protein export membrane protein 557 734 3.6E-61 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 SUPERFAMILY SSF82866 215 417 5.89E-37 T 28-03-2018 A21D_RS15315 cb88c2be2d5a9cfb45bd16027937d2ff 756 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 412 1.8E-108 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A21D_RS10910 2d44f67073194b649d89a42119619998 144 SUPERFAMILY SSF49764 5 137 5.58E-19 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS10910 2d44f67073194b649d89a42119619998 144 Gene3D G3DSA:2.60.40.790 1 139 1.9E-18 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS10910 2d44f67073194b649d89a42119619998 144 Pfam PF00011 Hsp20/alpha crystallin family 44 138 1.2E-9 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain A21D_RS14310 034dca475547c3245410d05086e65e5f 860 Pfam PF01580 FtsK/SpoIIIE family 505 642 5.7E-46 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A21D_RS14310 034dca475547c3245410d05086e65e5f 860 SMART SM00843 789 854 5.3E-37 T 28-03-2018 IPR018541 FtsK gamma domain A21D_RS14310 034dca475547c3245410d05086e65e5f 860 SMART SM00382 537 715 1.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14310 034dca475547c3245410d05086e65e5f 860 Pfam PF09397 Ftsk gamma domain 790 852 3.9E-28 T 28-03-2018 IPR018541 FtsK gamma domain A21D_RS14310 034dca475547c3245410d05086e65e5f 860 SUPERFAMILY SSF46785 789 855 9.16E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14310 034dca475547c3245410d05086e65e5f 860 SUPERFAMILY SSF52540 475 763 5.05E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14310 034dca475547c3245410d05086e65e5f 860 Gene3D G3DSA:3.40.50.300 226 858 8.7E-49 T 28-03-2018 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 311 1.3E-133 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 Gene3D G3DSA:3.40.47.10 162 310 1.5E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 4.8E-31 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 311 70.733 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 SUPERFAMILY SSF53901 4 311 1.34E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 Gene3D G3DSA:3.40.47.10 1 161 2.1E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13415 01a0dd9ac11b26bd2a3e080267d7ff8d 313 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 311 6.5E-36 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A21D_RS08310 f95b9ace17665a8454c7eb3466d28570 250 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08310 f95b9ace17665a8454c7eb3466d28570 250 Gene3D G3DSA:3.40.50.300 1 246 1.0E-61 T 28-03-2018 A21D_RS08310 f95b9ace17665a8454c7eb3466d28570 250 Pfam PF00005 ABC transporter 19 165 5.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08310 f95b9ace17665a8454c7eb3466d28570 250 SMART SM00382 28 213 1.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08310 f95b9ace17665a8454c7eb3466d28570 250 SUPERFAMILY SSF52540 3 216 1.84E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Gene3D G3DSA:1.10.10.60 102 132 0.062 T 28-03-2018 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Gene3D G3DSA:1.10.1660.10 1 101 4.7E-20 T 28-03-2018 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Pfam PF00376 MerR family regulatory protein 6 42 1.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Gene3D G3DSA:1.10.1660.10 133 179 1.3E-18 T 28-03-2018 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 SUPERFAMILY SSF46955 125 209 7.69E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 SMART SM00422 125 193 9.5E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 SMART SM00422 4 66 3.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Gene3D G3DSA:1.10.1660.10 180 246 0.0035 T 28-03-2018 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 Pfam PF13411 MerR HTH family regulatory protein 126 191 3.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS04945 46cb5254d61294c805b96f6bff46b636 247 SUPERFAMILY SSF46955 4 114 8.7E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS07680 1c97ff8c1c22ac6f46feab2b3194adaa 262 Pfam PF13847 Methyltransferase domain 51 155 4.4E-17 T 28-03-2018 IPR025714 Methyltransferase domain A21D_RS07680 1c97ff8c1c22ac6f46feab2b3194adaa 262 Gene3D G3DSA:3.40.50.150 3 248 4.4E-32 T 28-03-2018 A21D_RS07680 1c97ff8c1c22ac6f46feab2b3194adaa 262 SUPERFAMILY SSF53335 15 258 3.38E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 Gene3D G3DSA:3.40.630.30 165 319 2.4E-15 T 28-03-2018 A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 Gene3D G3DSA:3.40.630.30 3 164 3.9E-14 T 28-03-2018 A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 SUPERFAMILY SSF55729 185 311 7.93E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 Pfam PF00583 Acetyltransferase (GNAT) family 46 121 9.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 Pfam PF00583 Acetyltransferase (GNAT) family 188 304 3.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS02255 2fb47405dea7a606f0b6c08ee3959a00 323 SUPERFAMILY SSF55729 8 122 1.05E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.4E-82 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 PRINTS PR00094 Adenylate kinase signature 177 191 5.3E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 PRINTS PR00094 Adenylate kinase signature 4 17 5.3E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 PRINTS PR00094 Adenylate kinase signature 81 97 5.3E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 PRINTS PR00094 Adenylate kinase signature 32 46 5.3E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 PRINTS PR00094 Adenylate kinase signature 160 175 5.3E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 Pfam PF05191 Adenylate kinase, active site lid 127 162 7.0E-18 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 Pfam PF00406 Adenylate kinase 5 190 4.3E-61 T 28-03-2018 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 SUPERFAMILY SSF52540 4 212 7.58E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 Hamap MF_00235 Adenylate kinase [adk]. 1 213 52.952 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A21D_RS06270 7d42c16734f07edeb6ac300d43349ee9 214 Gene3D G3DSA:3.40.50.300 1 214 1.1E-67 T 28-03-2018 A21D_RS09725 5589a56be9f30f10b572220604e9db52 266 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 55 243 6.0E-51 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A21D_RS09725 5589a56be9f30f10b572220604e9db52 266 Pfam PF02096 60Kd inner membrane protein 55 243 6.8E-46 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SUPERFAMILY SSF50156 88 209 1.24E-21 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Pfam PF03572 Peptidase family S41 218 378 3.1E-44 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Gene3D G3DSA:3.30.750.44 45 116 1.2E-18 T 28-03-2018 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Gene3D G3DSA:1.10.101.10 389 467 6.1E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SMART SM00245 190 380 3.8E-57 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SUPERFAMILY SSF52096 212 384 6.3E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SUPERFAMILY SSF52096 50 135 6.3E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Gene3D G3DSA:3.90.226.10 199 388 1.2E-52 T 28-03-2018 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 68 387 1.7E-111 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Pfam PF13180 PDZ domain 118 196 2.7E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SUPERFAMILY SSF47090 390 457 1.07E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Pfam PF01471 Putative peptidoglycan binding domain 402 455 2.2E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 Gene3D G3DSA:2.30.42.10 117 198 2.2E-19 T 28-03-2018 A21D_RS00760 fe060d1fbfcc90d1abf9127ec9a198fd 483 SMART SM00228 117 188 2.2E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 SUPERFAMILY SSF88697 11 172 8.45E-51 T 28-03-2018 IPR015947 PUA-like domain A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 Pfam PF14306 PUA-like domain 11 167 9.9E-55 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 Gene3D G3DSA:3.40.50.620 185 385 1.9E-90 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 12 385 9.9E-142 T 28-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 Pfam PF01747 ATP-sulfurylase 176 385 2.7E-94 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 SUPERFAMILY SSF52374 176 386 6.68E-85 T 28-03-2018 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 33 389 49.277 T 28-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A21D_RS07480 9e7814fa2728436905d26ac31399cb9f 390 Gene3D G3DSA:3.10.400.10 11 184 3.2E-63 T 28-03-2018 A21D_RS09140 ea444cccebd5ab5829b74fe8d92bad4d 619 Gene3D G3DSA:3.40.50.720 403 563 2.0E-6 T 28-03-2018 A21D_RS09140 ea444cccebd5ab5829b74fe8d92bad4d 619 SUPERFAMILY SSF51735 404 494 6.9E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS09140 ea444cccebd5ab5829b74fe8d92bad4d 619 Pfam PF02254 TrkA-N domain 404 484 2.7E-9 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A21D_RS09140 ea444cccebd5ab5829b74fe8d92bad4d 619 Pfam PF00999 Sodium/hydrogen exchanger family 18 391 5.2E-34 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A21D_RS00055 642055de0befa25d2f87efd0140a24ca 116 SMART SM00507 23 91 1.2E-6 T 28-03-2018 IPR003615 HNH nuclease A21D_RS00055 642055de0befa25d2f87efd0140a24ca 116 Gene3D G3DSA:3.40.1800.10 14 109 3.2E-11 T 28-03-2018 A21D_RS03475 c717694985f4fb236e5301d2ae43ac42 130 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 4 123 1.2E-21 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 A21D_RS03475 c717694985f4fb236e5301d2ae43ac42 130 SUPERFAMILY SSF140931 53 100 3.27E-6 T 28-03-2018 IPR003812 Fido domain A21D_RS03475 c717694985f4fb236e5301d2ae43ac42 130 Pfam PF02661 Fic/DOC family 3 87 1.9E-12 T 28-03-2018 IPR003812 Fido domain A21D_RS03475 c717694985f4fb236e5301d2ae43ac42 130 Gene3D G3DSA:1.10.3290.10 29 126 1.9E-9 T 28-03-2018 IPR003812 Fido domain A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 Pfam PF01368 DHH family 84 224 2.1E-10 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 Pfam PF02272 DHHA1 domain 313 431 3.0E-13 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 562 756 4.9E-47 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 SUPERFAMILY SSF64182 57 446 6.41E-113 T 28-03-2018 A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 27 556 1.7E-185 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A21D_RS15325 f0ce3a0a8f61bc13c3aaca70f98eecf1 774 Gene3D G3DSA:3.90.1640.10 61 251 7.1E-26 T 28-03-2018 A21D_RS04965 07d3ac34d3627951088ad034086db8cf 302 SUPERFAMILY SSF103481 36 141 9.16E-14 T 28-03-2018 A21D_RS04965 07d3ac34d3627951088ad034086db8cf 302 SUPERFAMILY SSF103481 188 290 3.01E-13 T 28-03-2018 A21D_RS04965 07d3ac34d3627951088ad034086db8cf 302 Pfam PF00892 EamA-like transporter family 152 287 1.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS04965 07d3ac34d3627951088ad034086db8cf 302 Pfam PF00892 EamA-like transporter family 8 138 5.6E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS18670 69a30d11da91480a9c2441fa5ffe1f44 229 SUPERFAMILY SSF140423 22 211 3.14E-54 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like A21D_RS18670 69a30d11da91480a9c2441fa5ffe1f44 229 Pfam PF10368 Putative cell-wall binding lipoprotein 14 213 2.9E-67 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like A21D_RS18670 69a30d11da91480a9c2441fa5ffe1f44 229 Gene3D G3DSA:1.20.120.570 12 211 1.4E-47 T 28-03-2018 A21D_RS04440 427af5c4bce3337aa847755b15eb0eeb 139 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 138 9.0E-58 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A21D_RS04440 427af5c4bce3337aa847755b15eb0eeb 139 Gene3D G3DSA:3.10.129.10 1 139 2.0E-55 T 28-03-2018 A21D_RS04440 427af5c4bce3337aa847755b15eb0eeb 139 Pfam PF07977 FabA-like domain 10 133 5.0E-35 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A21D_RS04440 427af5c4bce3337aa847755b15eb0eeb 139 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 139 32.768 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A21D_RS04440 427af5c4bce3337aa847755b15eb0eeb 139 SUPERFAMILY SSF54637 1 138 3.74E-48 T 28-03-2018 IPR029069 HotDog domain A21D_RS05940 603235c66aa615f430c6e292d2649a6f 372 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 24 362 5.1E-132 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A21D_RS05940 603235c66aa615f430c6e292d2649a6f 372 Gene3D G3DSA:3.40.50.970 2 363 5.2E-86 T 28-03-2018 A21D_RS05940 603235c66aa615f430c6e292d2649a6f 372 Pfam PF00676 Dehydrogenase E1 component 54 335 2.7E-83 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A21D_RS05940 603235c66aa615f430c6e292d2649a6f 372 SUPERFAMILY SSF52518 20 365 3.4E-94 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS04445 20448e790df09418f3b8e40bce26e4e4 100 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 51 96 3.0E-13 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA A21D_RS04445 20448e790df09418f3b8e40bce26e4e4 100 Pfam PF11772 DNA-directed RNA polymerase subunit beta 53 98 3.3E-20 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 SUPERFAMILY SSF52283 3 133 1.42E-30 T 28-03-2018 A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 300 4.5E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 331 1.3E-23 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 Gene3D G3DSA:3.40.50.720 118 300 6.2E-45 T 28-03-2018 A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 SUPERFAMILY SSF51735 103 301 6.23E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS13605 c6265aa8ccb397e6a946ca16de2df8be 341 Gene3D G3DSA:3.40.50.720 3 117 3.4E-21 T 28-03-2018 A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 Pfam PF00005 ABC transporter 20 162 8.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 SMART SM00382 29 212 1.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 SUPERFAMILY SSF52540 4 243 2.52E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 Gene3D G3DSA:2.40.50.140 282 342 5.3E-8 T 28-03-2018 A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 Gene3D G3DSA:3.40.50.300 1 250 2.6E-70 T 28-03-2018 A21D_RS19140 1d518cd486ac817522be800a0bb617aa 371 SUPERFAMILY SSF50331 237 357 8.5E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 Gene3D G3DSA:3.90.650.10 164 346 1.8E-45 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 PIRSF PIRSF036407 1 349 3.2E-123 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 TIGRFAM TIGR00476 selD: selenide, water dikinase 7 316 1.2E-126 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 SUPERFAMILY SSF56042 164 344 2.24E-50 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 51 157 3.6E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 SUPERFAMILY SSF55326 8 161 3.27E-43 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 347 6.1E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 Hamap MF_00625 Selenide, water dikinase [selD]. 5 348 42.855 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 A21D_RS13445 c2d1ece12a7424c20b585ee464949d64 349 Gene3D G3DSA:3.30.1330.10 1 162 3.5E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 192 420 3.8E-88 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 SUPERFAMILY SSF51230 1 95 2.22E-28 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 SUPERFAMILY SSF52777 182 420 8.45E-87 T 28-03-2018 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Gene3D G3DSA:3.30.559.10 174 420 3.1E-89 T 28-03-2018 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 SUPERFAMILY SSF47005 115 160 6.15E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Gene3D G3DSA:2.40.50.100 47 120 3.6E-9 T 28-03-2018 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Pfam PF00364 Biotin-requiring enzyme 5 75 2.7E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Gene3D G3DSA:3.90.1170.30 2 46 1.2E-13 T 28-03-2018 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Pfam PF02817 e3 binding domain 121 155 9.0E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS18655 61ce0a6b0a10c59a0947dcbc1ea04da8 422 Gene3D G3DSA:4.10.320.10 121 160 3.2E-19 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 Gene3D G3DSA:3.40.50.300 2 205 1.2E-54 T 28-03-2018 A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 3 198 3.9E-62 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 Pfam PF02223 Thymidylate kinase 8 198 2.4E-58 T 28-03-2018 A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 SUPERFAMILY SSF52540 3 199 1.28E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06865 d2a6584b3c0890f12e9ce055ee48b7cc 209 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.024 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A21D_RS12280 6cc5c72c791c52b185921c7937295125 90 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 85 1.1E-13 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12280 6cc5c72c791c52b185921c7937295125 90 SUPERFAMILY SSF52794 1 87 4.71E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12280 6cc5c72c791c52b185921c7937295125 90 Gene3D G3DSA:3.40.50.2300 1 90 5.5E-20 T 28-03-2018 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SUPERFAMILY SSF48452 13 214 6.45E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.25.40.10 178 218 5.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.10.287.1110 152 167 5.1E-5 T 28-03-2018 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Pfam PF13181 Tetratricopeptide repeat 103 134 4.3E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.10.150.160 81 112 8.5E-7 T 28-03-2018 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Pfam PF13174 Tetratricopeptide repeat 6 33 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Pfam PF13424 Tetratricopeptide repeat 38 98 2.6E-7 T 28-03-2018 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.25.40.10 1 68 7.7E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 69 102 1.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 35 68 0.026 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 137 170 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 1 34 470.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 103 136 1.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 SMART SM00028 171 204 2.5E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Pfam PF00515 Tetratricopeptide repeat 172 204 9.0E-7 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.25.40.10 113 151 5.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.10.8.10 168 177 0.29 T 28-03-2018 A21D_RS15395 82d062973458246e42259ac4942895f3 221 Gene3D G3DSA:1.10.8.10 69 80 0.0032 T 28-03-2018 A21D_RS07575 d1819d2205447709d39d20bc231cb49c 120 Pfam PF00106 short chain dehydrogenase 11 118 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS07575 d1819d2205447709d39d20bc231cb49c 120 Gene3D G3DSA:3.40.50.720 1 119 6.9E-16 T 28-03-2018 A21D_RS07575 d1819d2205447709d39d20bc231cb49c 120 SUPERFAMILY SSF51735 7 115 1.1E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 SUPERFAMILY SSF56042 573 739 2.84E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Gene3D G3DSA:3.30.1330.10 419 567 3.4E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 SUPERFAMILY SSF55326 18 201 4.19E-51 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 SUPERFAMILY SSF55326 406 568 6.54E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 PIRSF PIRSF001587 8 741 0.0 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 742 313.755 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 1.6E-301 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 SUPERFAMILY SSF56042 205 430 3.59E-55 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Gene3D G3DSA:3.30.1330.10 21 199 6.4E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Gene3D G3DSA:3.90.650.10 203 378 3.1E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Gene3D G3DSA:3.90.650.10 569 740 8.8E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 91 194 4.4E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 561 8.0E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 357 8.4E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10950 60e4e646ef8164a1c37a5107abe6074a 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 712 2.2E-15 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 SUPERFAMILY SSF49899 336 478 3.48E-16 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 15 453 2.1E-164 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 Gene3D G3DSA:2.115.10.20 36 361 1.5E-104 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 SMART SM00640 31 443 4.2E-138 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 SUPERFAMILY SSF75005 22 337 5.65E-111 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 31 44 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 Gene3D G3DSA:2.60.120.560 362 478 7.1E-10 T 28-03-2018 A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 31 336 1.3E-105 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal A21D_RS01660 a5414d66f71ab077131c57157bf6bd62 483 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 415 477 1.9E-8 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal A21D_RS13410 63ef8da4c9c93a7c06f46c86c166ec45 316 Gene3D G3DSA:3.40.50.2300 26 142 3.4E-27 T 28-03-2018 A21D_RS13410 63ef8da4c9c93a7c06f46c86c166ec45 316 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 27 291 7.6E-55 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A21D_RS13410 63ef8da4c9c93a7c06f46c86c166ec45 316 SUPERFAMILY SSF53822 26 239 4.71E-13 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS13410 63ef8da4c9c93a7c06f46c86c166ec45 316 Gene3D G3DSA:3.40.50.2300 143 313 1.6E-27 T 28-03-2018 A21D_RS00625 75900a6890c18268fc6b7aef969f39c8 71 Gene3D G3DSA:3.40.50.1390 1 71 5.9E-16 T 28-03-2018 A21D_RS00625 75900a6890c18268fc6b7aef969f39c8 71 Pfam PF00239 Resolvase, N terminal domain 8 70 2.4E-12 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS00625 75900a6890c18268fc6b7aef969f39c8 71 SUPERFAMILY SSF53041 1 71 9.55E-16 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Gene3D G3DSA:3.40.50.620 127 246 5.4E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 SUPERFAMILY SSF52374 4 316 1.02E-112 T 28-03-2018 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 1.8E-125 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Gene3D G3DSA:1.10.1160.10 247 333 1.3E-27 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Gene3D G3DSA:1.10.10.350 389 489 1.3E-26 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 SUPERFAMILY SSF48163 300 482 1.12E-44 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.201 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Gene3D G3DSA:3.40.50.620 5 126 4.4E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 483 5.4E-185 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 Gene3D G3DSA:1.10.8.70 334 384 4.3E-5 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 6.4E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 6.4E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 6.4E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 6.4E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A21D_RS06490 3dd1e3c29936c467b3fc693b9689fc08 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 6.4E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 SMART SM00861 4 179 2.7E-69 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 SUPERFAMILY SSF52922 188 325 2.36E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 5.6E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 2.3E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 SUPERFAMILY SSF52518 2 204 4.22E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 Gene3D G3DSA:3.40.50.920 195 326 2.9E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS16200 d1936f9a1043f45861ebd778bb6a41d1 327 Gene3D G3DSA:3.40.50.970 2 194 1.1E-72 T 28-03-2018 A21D_RS15295 0a1f663da0b87dbc6cec5ff96eaab5b2 129 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 8 120 2.2E-23 T 28-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A21D_RS15295 0a1f663da0b87dbc6cec5ff96eaab5b2 129 Pfam PF12670 Protein of unknown function (DUF3792) 7 117 1.0E-18 T 28-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A21D_RS14500 fa9c934ca90ca8b6a4845ab8dd751749 315 Pfam PF01368 DHH family 16 154 1.4E-14 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS14500 fa9c934ca90ca8b6a4845ab8dd751749 315 Gene3D G3DSA:3.90.1640.10 2 198 3.5E-44 T 28-03-2018 A21D_RS14500 fa9c934ca90ca8b6a4845ab8dd751749 315 SUPERFAMILY SSF64182 14 295 3.27E-74 T 28-03-2018 A21D_RS14500 fa9c934ca90ca8b6a4845ab8dd751749 315 Pfam PF02272 DHHA1 domain 180 307 1.2E-13 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 4.6E-8 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 4.6E-8 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 405 424 4.6E-8 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 4.6E-8 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 Gene3D G3DSA:1.20.1250.20 255 459 7.6E-18 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 Gene3D G3DSA:1.20.1250.20 4 204 2.4E-30 T 28-03-2018 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 Pfam PF07690 Major Facilitator Superfamily 23 414 1.7E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 SUPERFAMILY SSF103473 251 451 4.45E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS06000 e859108d8ddaa99e0b3b6522b1923252 460 SUPERFAMILY SSF103473 7 199 4.45E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS12825 d6575feb186d5303812a236742c16618 380 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 1.7E-19 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Pfam PF13646 HEAT repeats 300 364 2.1E-9 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 SUPERFAMILY SSF54862 164 279 1.34E-15 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 342 6.0E-130 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.9E-16 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Gene3D G3DSA:3.30.70.20 51 195 5.9E-5 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Gene3D G3DSA:3.30.70.20 196 267 7.6E-9 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 SUPERFAMILY SSF48371 298 372 7.68E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Gene3D G3DSA:1.25.40.70 268 372 8.3E-6 T 28-03-2018 A21D_RS12825 d6575feb186d5303812a236742c16618 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 42.886 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 Gene3D G3DSA:3.30.420.40 252 517 5.7E-66 T 28-03-2018 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 2.1E-36 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 6 510 5.9E-245 T 28-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 PIRSF PIRSF000538 4 507 2.3E-141 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 SUPERFAMILY SSF53067 253 500 1.71E-65 T 28-03-2018 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 SUPERFAMILY SSF53067 6 252 5.99E-68 T 28-03-2018 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 4.7E-70 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A21D_RS08910 25345a107cfacbcd61f6955d6fd10226 517 Gene3D G3DSA:3.30.420.40 2 251 1.0E-67 T 28-03-2018 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 SUPERFAMILY SSF55874 2 212 3.01E-62 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 SUPERFAMILY SSF110942 512 624 1.7E-29 T 28-03-2018 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 Gene3D G3DSA:3.30.565.10 26 220 4.4E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 Pfam PF00183 Hsp90 protein 185 222 9.2E-7 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 Pfam PF00183 Hsp90 protein 226 624 6.7E-113 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 SUPERFAMILY SSF54211 237 488 9.86E-83 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 151 1.2E-12 T 28-03-2018 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 165 182 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 90 107 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 72 89 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 23 45 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 115 137 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 2 22 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PRINTS PR00775 90kDa heat shock protein signature 188 206 4.4E-54 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 625 26.792 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 A21D_RS12460 a1d9669e7adef65bb9a0c12fd8efafed 625 PIRSF PIRSF002583 1 625 3.4E-203 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 53 878 2.0E-216 T 28-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF81665 679 881 6.93E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF81665 225 318 6.93E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF81665 1 114 6.93E-133 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Gene3D G3DSA:1.20.1110.10 652 883 2.2E-70 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF81660 332 531 9.37E-51 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF81653 114 224 3.01E-31 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Gene3D G3DSA:3.40.1110.10 287 521 9.5E-57 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 642 1.6E-23 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 1.6E-20 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Gene3D G3DSA:2.70.150.10 11 225 2.7E-56 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Gene3D G3DSA:3.40.50.1000 522 651 5.9E-18 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF56784 483 733 1.67E-59 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SUPERFAMILY SSF56784 322 342 1.67E-59 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 629 645 2.2E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 661 686 2.2E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 601 617 2.2E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 486 504 2.2E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Pfam PF00689 Cation transporting ATPase, C-terminus 713 883 1.7E-50 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 600 720 6.4E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 184 2.0E-22 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 208 346 1.6E-27 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 422 574 3.2E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 Pfam PF00122 E1-E2 ATPase 110 304 1.7E-54 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 665 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 538 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 6.6E-39 T 28-03-2018 A21D_RS18230 ccee90e925d16db8ba6af0f1dfb19056 884 SMART SM00831 2 76 1.4E-25 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 Gene3D G3DSA:3.40.470.10 2 166 1.6E-44 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 SMART SM00987 8 163 6.1E-4 T 28-03-2018 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 SMART SM00986 8 163 6.1E-4 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 Pfam PF03167 Uracil DNA glycosylase superfamily 11 159 6.3E-10 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 SUPERFAMILY SSF52141 7 165 7.72E-30 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A21D_RS12740 62ca500ccc2a779394741f4467b67648 166 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 6 159 3.1E-46 T 28-03-2018 IPR026353 Hypoxanthine-DNA glycosylase A21D_RS10315 01b8721adfd90d28e9f01bfae682cdc4 157 Gene3D G3DSA:1.20.1170.10 4 138 8.6E-4 T 28-03-2018 A21D_RS14545 4006340923d0638440212a1a2a698752 286 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 282 6.4E-122 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 Gene3D G3DSA:3.90.226.10 15 286 3.3E-67 T 28-03-2018 A21D_RS14545 4006340923d0638440212a1a2a698752 286 Pfam PF01039 Carboxyl transferase domain 62 241 4.7E-20 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A21D_RS14545 4006340923d0638440212a1a2a698752 286 SUPERFAMILY SSF52096 28 281 4.26E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS14545 4006340923d0638440212a1a2a698752 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 2.5E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 2.5E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 2.5E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 2.5E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 2.5E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS14545 4006340923d0638440212a1a2a698752 286 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 38.337 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 Gene3D G3DSA:1.20.1260.10 1 148 7.9E-38 T 28-03-2018 IPR012347 Ferritin-related A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 ProSitePatterns PS00819 Dps protein family signature 2. 54 68 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 PIRSF PIRSF005900 1 148 1.9E-43 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 ProSitePatterns PS00818 Dps protein family signature 1. 28 44 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 Pfam PF00210 Ferritin-like domain 8 147 5.1E-22 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 28 44 1.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 52 68 1.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 1.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A21D_RS17530 f75f6adab36fd5f419ae51ebecc4af20 148 SUPERFAMILY SSF47240 4 146 2.51E-34 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 SUPERFAMILY SSF90123 32 349 1.28E-82 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 Gene3D G3DSA:3.40.50.300 350 605 2.2E-74 T 28-03-2018 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 Gene3D G3DSA:1.20.1560.10 18 349 1.2E-82 T 28-03-2018 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 SMART SM00382 390 576 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 Pfam PF00005 ABC transporter 381 530 4.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 Pfam PF00664 ABC transporter transmembrane region 49 320 1.3E-58 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS13580 ba6309d40478c29822d97858432b23f2 605 SUPERFAMILY SSF52540 356 600 5.88E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 Gene3D G3DSA:3.50.50.60 1 368 1.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 350 1.3E-90 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 Pfam PF01266 FAD dependent oxidoreductase 7 345 6.7E-59 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 SUPERFAMILY SSF54373 220 306 7.19E-14 T 28-03-2018 A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 SUPERFAMILY SSF51905 307 354 8.55E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS12050 e7a204ab64e6e528e2e3136621ca4754 369 SUPERFAMILY SSF51905 4 220 8.55E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13120 5d776d47f2e4ff201f082b63621927af 119 Pfam PF12732 YtxH-like protein 9 91 7.6E-12 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 Pfam PF00574 Clp protease 39 184 2.2E-31 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 SUPERFAMILY SSF52096 12 187 3.94E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 Gene3D G3DSA:3.90.226.10 3 201 3.8E-32 T 28-03-2018 A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 PRINTS PR00127 Clp protease catalytic subunit P signature 85 102 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 PRINTS PR00127 Clp protease catalytic subunit P signature 161 180 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS17310 b7a3242efe4631456f1075cd305495c7 246 PRINTS PR00127 Clp protease catalytic subunit P signature 54 74 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 Gene3D G3DSA:3.30.450.40 204 341 6.3E-40 T 28-03-2018 IPR029016 GAF domain-like A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 Gene3D G3DSA:1.10.10.10 1 83 1.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 30.81 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 SUPERFAMILY SSF46785 1 81 1.59E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 SUPERFAMILY SSF55781 71 336 2.55E-63 T 28-03-2018 IPR029016 GAF domain-like A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 333 1.5E-101 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 PIRSF PIRSF005485 1 339 4.2E-108 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 Gene3D G3DSA:3.30.390.60 127 203 1.3E-18 T 28-03-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain A21D_RS15630 a0f884dbaa744d964a6519f2a757a998 343 Pfam PF01628 HrcA protein C terminal domain 103 321 5.9E-59 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A21D_RS02035 5f7da62c3c037366dd850614c261f289 252 SUPERFAMILY SSF88713 6 248 1.02E-69 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS02035 5f7da62c3c037366dd850614c261f289 252 Gene3D G3DSA:3.20.20.370 2 249 4.0E-72 T 28-03-2018 A21D_RS02035 5f7da62c3c037366dd850614c261f289 252 Pfam PF04794 YdjC-like protein 7 236 1.1E-53 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like A21D_RS01135 790234c624c3fe96d7a6d429d6570693 680 Gene3D G3DSA:3.30.420.40 4 291 2.7E-10 T 28-03-2018 A21D_RS01135 790234c624c3fe96d7a6d429d6570693 680 Pfam PF01968 Hydantoinase/oxoprolinase 200 486 1.0E-85 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 A21D_RS01135 790234c624c3fe96d7a6d429d6570693 680 Gene3D G3DSA:3.30.420.40 292 562 0.04 T 28-03-2018 A21D_RS01135 790234c624c3fe96d7a6d429d6570693 680 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 179 2.5E-48 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 A21D_RS01850 433c6c65e7295eaa06db176c52f6015e 257 SUPERFAMILY SSF52096 1 256 4.29E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS01850 433c6c65e7295eaa06db176c52f6015e 257 Gene3D G3DSA:3.90.226.10 1 214 4.4E-66 T 28-03-2018 A21D_RS01850 433c6c65e7295eaa06db176c52f6015e 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 4.9E-66 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS01850 433c6c65e7295eaa06db176c52f6015e 257 Gene3D G3DSA:1.10.12.10 215 256 1.7E-11 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS01850 433c6c65e7295eaa06db176c52f6015e 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS18845 c007ed8ac3717965c0506bbd5662a878 333 Gene3D G3DSA:3.40.47.10 45 322 3.5E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS18845 c007ed8ac3717965c0506bbd5662a878 333 PIRSF PIRSF011570 1 333 3.5E-161 T 28-03-2018 IPR010894 Stage V sporulation AD A21D_RS18845 c007ed8ac3717965c0506bbd5662a878 333 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 1.3E-151 T 28-03-2018 IPR010894 Stage V sporulation AD A21D_RS18845 c007ed8ac3717965c0506bbd5662a878 333 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 1.0E-154 T 28-03-2018 IPR010894 Stage V sporulation AD A21D_RS18845 c007ed8ac3717965c0506bbd5662a878 333 SUPERFAMILY SSF53901 42 309 4.01E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS06670 0a99adc26279a76947582ef566292507 464 SUPERFAMILY SSF56037 341 458 3.4E-21 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A21D_RS06670 0a99adc26279a76947582ef566292507 464 SUPERFAMILY SSF82829 216 326 1.8E-6 T 28-03-2018 A21D_RS06670 0a99adc26279a76947582ef566292507 464 SUPERFAMILY SSF52402 7 231 1.66E-57 T 28-03-2018 A21D_RS06670 0a99adc26279a76947582ef566292507 464 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 208 1.1E-57 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A21D_RS06670 0a99adc26279a76947582ef566292507 464 Pfam PF01171 PP-loop family 21 204 5.6E-57 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A21D_RS06670 0a99adc26279a76947582ef566292507 464 Pfam PF11734 TilS substrate C-terminal domain 385 453 2.0E-17 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A21D_RS06670 0a99adc26279a76947582ef566292507 464 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 385 431 2.9E-19 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A21D_RS06670 0a99adc26279a76947582ef566292507 464 Gene3D G3DSA:3.40.50.620 11 209 2.1E-44 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS06670 0a99adc26279a76947582ef566292507 464 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 320 22.352 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A21D_RS06670 0a99adc26279a76947582ef566292507 464 SMART SM00977 385 459 9.0E-27 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A21D_RS09335 e878d05b6916dddbd3b19f6565523a2c 164 SUPERFAMILY SSF55040 11 159 6.28E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A21D_RS09335 e878d05b6916dddbd3b19f6565523a2c 164 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 162 34.292 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A21D_RS09335 e878d05b6916dddbd3b19f6565523a2c 164 Gene3D G3DSA:3.30.70.640 2 162 7.9E-65 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A21D_RS09335 e878d05b6916dddbd3b19f6565523a2c 164 Pfam PF01967 MoaC family 15 154 9.6E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A21D_RS09335 e878d05b6916dddbd3b19f6565523a2c 164 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 156 1.1E-60 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 2.3E-92 T 28-03-2018 A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 SUPERFAMILY SSF56219 1 250 1.44E-76 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 Gene3D G3DSA:3.60.10.10 1 251 3.4E-54 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 242 3.9E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 5.4E-95 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A21D_RS03290 b63706367c64e0fba5723cbc55272c04 252 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Gene3D G3DSA:3.30.980.10 555 702 9.8E-44 T 28-03-2018 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 9.5E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 9.5E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 9.5E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 9.5E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 9.5E-32 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 SUPERFAMILY SSF55681 5 245 5.47E-90 T 28-03-2018 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 SUPERFAMILY SSF50447 456 554 4.37E-20 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 SUPERFAMILY SSF101353 246 443 4.45E-64 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Gene3D G3DSA:3.30.930.10 3 242 2.9E-97 T 28-03-2018 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Pfam PF02272 DHHA1 domain 737 871 5.3E-26 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 177.102 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 SUPERFAMILY SSF55186 554 710 9.81E-50 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Pfam PF01411 tRNA synthetases class II (A) 8 556 5.0E-207 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 SMART SM00863 655 698 2.4E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.1E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS15420 ff6e44e3179c0352e6642dbab765b81b 879 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 Gene3D G3DSA:1.10.10.10 44 118 9.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 ProSitePatterns PS00894 DeoR-type HTH domain signature. 56 90 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 SMART SM00420 56 108 4.6E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 SUPERFAMILY SSF100950 125 285 2.09E-24 T 28-03-2018 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 Pfam PF00455 DeoR C terminal sensor domain 127 284 4.0E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 Pfam PF08220 DeoR-like helix-turn-helix domain 56 107 5.3E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 Gene3D G3DSA:3.40.50.1360 124 290 4.5E-29 T 28-03-2018 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 SMART SM01134 123 285 2.3E-53 T 28-03-2018 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 74 88 5.4E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 88 106 5.4E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05735 2667dda14a2eb9b95ceaa27319daf259 303 SUPERFAMILY SSF46785 55 112 1.42E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 Gene3D G3DSA:3.40.800.20 3 371 1.2E-91 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 334 350 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01272 Acetoin utilisation ACUC protein signature 351 370 4.3E-42 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 Pfam PF00850 Histone deacetylase domain 22 319 8.3E-76 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 1.3E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 1.3E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 1.3E-17 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A21D_RS14360 45f0299c3ad868f12faca45d9bab1536 391 SUPERFAMILY SSF52768 6 370 2.3E-103 T 28-03-2018 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 SUPERFAMILY SSF55957 512 572 9.55E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 SUPERFAMILY SSF55957 444 481 9.55E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 486 561 2.2E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 SUPERFAMILY SSF53738 33 221 4.32E-48 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 SUPERFAMILY SSF53738 209 318 1.91E-18 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Gene3D G3DSA:3.30.310.50 467 576 2.0E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Gene3D G3DSA:3.40.120.10 18 214 5.1E-54 T 28-03-2018 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 SUPERFAMILY SSF53738 307 454 3.92E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 449 1.1E-21 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 315 2.3E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Gene3D G3DSA:3.40.120.10 215 337 5.2E-26 T 28-03-2018 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Gene3D G3DSA:3.40.120.10 338 451 9.1E-37 T 28-03-2018 A21D_RS09160 ca67f8cab88e59968b52304b34c678d5 577 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 44 182 2.9E-40 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS02680 5fab6712e97f69edfeca173f7fb3e6a8 254 Pfam PF02706 Chain length determinant protein 3 95 7.2E-18 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A21D_RS02680 5fab6712e97f69edfeca173f7fb3e6a8 254 Pfam PF13807 G-rich domain on putative tyrosine kinase 143 195 2.5E-7 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain A21D_RS02680 5fab6712e97f69edfeca173f7fb3e6a8 254 Gene3D G3DSA:3.30.1890.10 37 153 2.1E-9 T 28-03-2018 A21D_RS02320 38529dad93aae359fc4ba642667d42c1 392 Pfam PF00155 Aminotransferase class I and II 31 384 5.9E-37 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS02320 38529dad93aae359fc4ba642667d42c1 392 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 387 1.6E-111 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A21D_RS02320 38529dad93aae359fc4ba642667d42c1 392 SUPERFAMILY SSF53383 1 385 4.76E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS02320 38529dad93aae359fc4ba642667d42c1 392 Gene3D G3DSA:3.40.640.10 66 282 2.5E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS02320 38529dad93aae359fc4ba642667d42c1 392 Gene3D G3DSA:3.90.1150.10 283 390 3.7E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 PRINTS PR00344 Bacterial sensor protein C-terminal signature 256 270 5.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 284 5.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 308 5.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 SUPERFAMILY SSF55874 183 327 1.44E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 SMART SM00387 218 330 5.6E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 Gene3D G3DSA:3.30.565.10 145 328 1.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00430 a735a78f02bb8e9f71dc3bb9315e3395 336 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 219 328 3.1E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10400 d43873c6e4c70212c22310f01b3ea3b0 309 SUPERFAMILY SSF56563 117 306 9.94E-7 T 28-03-2018 A21D_RS10400 d43873c6e4c70212c22310f01b3ea3b0 309 Pfam PF05065 Phage capsid family 117 297 5.9E-9 T 28-03-2018 IPR024455 Phage capsid A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 5.7E-155 T 28-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Gene3D G3DSA:1.10.601.10 5 111 3.2E-33 T 28-03-2018 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Gene3D G3DSA:1.10.1270.10 176 260 2.7E-16 T 28-03-2018 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PRINTS PR00046 Major sigma-70 factor signature 91 99 1.9E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PRINTS PR00046 Major sigma-70 factor signature 211 223 1.9E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PRINTS PR00046 Major sigma-70 factor signature 243 254 1.9E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PRINTS PR00046 Major sigma-70 factor signature 67 80 1.9E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PRINTS PR00046 Major sigma-70 factor signature 228 243 1.9E-11 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Pfam PF04539 Sigma-70 region 3 125 176 8.8E-8 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Pfam PF04545 Sigma-70, region 4 208 254 1.1E-12 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 257 1.5E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Gene3D G3DSA:1.10.10.10 112 164 1.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 228 254 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 67 80 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 Pfam PF04542 Sigma-70 region 2 43 111 6.4E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PIRSF PIRSF000770 124 157 7.5 T 28-03-2018 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PIRSF PIRSF000770 14 124 3.6E-18 T 28-03-2018 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 PIRSF PIRSF000770 159 260 4.9E-15 T 28-03-2018 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 SUPERFAMILY SSF88659 176 258 1.83E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 SUPERFAMILY SSF88659 115 191 2.05E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 38 258 4.2E-82 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS18355 f91d26705d60c42dc37af14fd753af5e 260 SUPERFAMILY SSF88946 12 111 2.35E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 Pfam PF00924 Mechanosensitive ion channel 137 338 2.0E-61 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 SUPERFAMILY SSF82861 94 178 3.92E-11 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 SUPERFAMILY SSF82689 247 350 4.58E-16 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 SUPERFAMILY SSF50182 180 245 8.17E-18 T 28-03-2018 IPR010920 LSM domain A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 Gene3D G3DSA:2.30.30.60 195 244 1.3E-15 T 28-03-2018 A21D_RS03795 1cc550545ef3330b14c69554a2f37116 365 Gene3D G3DSA:3.30.70.100 245 344 1.2E-16 T 28-03-2018 A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 Pfam PF00005 ABC transporter 335 468 1.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 Pfam PF00005 ABC transporter 18 184 7.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 SUPERFAMILY SSF52540 2 92 1.33E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 SUPERFAMILY SSF52540 125 256 1.33E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 SMART SM00382 26 228 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 SMART SM00382 344 514 0.0051 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 SUPERFAMILY SSF52540 296 528 3.04E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 Gene3D G3DSA:3.40.50.300 287 540 4.0E-39 T 28-03-2018 A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 Gene3D G3DSA:3.40.50.300 1 286 3.2E-57 T 28-03-2018 A21D_RS09070 4e75a9c2f6d5fb3e22d96c1f34545498 540 Pfam PF12848 ABC transporter 224 307 1.4E-18 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 302 4.6E-60 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 Gene3D G3DSA:3.40.50.720 1 176 5.3E-28 T 28-03-2018 A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 Gene3D G3DSA:1.10.1040.10 178 305 1.5E-24 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 SUPERFAMILY SSF51735 1 165 4.11E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 300 4.3E-22 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 6.1E-33 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS02970 b6c7a5ada4e26aa8cf5c73aa9b0954a1 305 SUPERFAMILY SSF48179 178 302 3.74E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS03090 0455f2335bf55282b7e2942439e47944 241 Gene3D G3DSA:3.40.30.10 1 216 9.9E-55 T 28-03-2018 A21D_RS03090 0455f2335bf55282b7e2942439e47944 241 Pfam PF01323 DSBA-like thioredoxin domain 2 204 4.7E-44 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A21D_RS03090 0455f2335bf55282b7e2942439e47944 241 SUPERFAMILY SSF52833 1 210 1.27E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS17230 e1ee8da4b42ba0f9d81cf12081463bd1 422 SMART SM00646 70 195 2.7E-8 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS17230 e1ee8da4b42ba0f9d81cf12081463bd1 422 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 164 3.8E-25 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS17230 e1ee8da4b42ba0f9d81cf12081463bd1 422 SUPERFAMILY SSF53187 3 200 5.65E-25 T 28-03-2018 A21D_RS17230 e1ee8da4b42ba0f9d81cf12081463bd1 422 Gene3D G3DSA:3.40.630.40 3 200 5.4E-29 T 28-03-2018 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 Gene3D G3DSA:3.10.580.10 264 369 4.1E-24 T 28-03-2018 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 SUPERFAMILY SSF52540 1 241 3.19E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 Gene3D G3DSA:3.40.50.300 1 263 1.2E-77 T 28-03-2018 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 SUPERFAMILY SSF54631 250 368 3.0E-26 T 28-03-2018 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 Pfam PF00005 ABC transporter 19 163 1.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 Pfam PF00571 CBS domain 251 297 1.7E-9 T 28-03-2018 IPR000644 CBS domain A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 Pfam PF00571 CBS domain 311 363 1.0E-8 T 28-03-2018 IPR000644 CBS domain A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 371 1.1E-153 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 SMART SM00116 318 366 1.9E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 SMART SM00116 258 306 3.3E-7 T 28-03-2018 IPR000644 CBS domain A21D_RS08000 0c0bbbe43b4653c1dd2d48a9d10c5f17 378 SMART SM00382 27 213 1.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04365 4c12de87bc18cd714433405a2026deb2 371 Gene3D G3DSA:3.90.350.10 83 310 7.4E-26 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS04365 4c12de87bc18cd714433405a2026deb2 371 SUPERFAMILY SSF53098 117 359 8.34E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS04365 4c12de87bc18cd714433405a2026deb2 371 Pfam PF01609 Transposase DDE domain 122 329 1.4E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS04365 4c12de87bc18cd714433405a2026deb2 371 Pfam PF14294 Domain of unknown function (DUF4372) 7 75 3.4E-10 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS06130 4c12de87bc18cd714433405a2026deb2 371 Gene3D G3DSA:3.90.350.10 83 310 7.4E-26 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS06130 4c12de87bc18cd714433405a2026deb2 371 SUPERFAMILY SSF53098 117 359 8.34E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS06130 4c12de87bc18cd714433405a2026deb2 371 Pfam PF01609 Transposase DDE domain 122 329 1.4E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS06130 4c12de87bc18cd714433405a2026deb2 371 Pfam PF14294 Domain of unknown function (DUF4372) 7 75 3.4E-10 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS10500 66999a90b398a71f8b492210e4a401c7 359 SMART SM00644 14 152 5.7E-33 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS10500 66999a90b398a71f8b492210e4a401c7 359 SUPERFAMILY SSF55846 13 157 1.7E-47 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS10500 66999a90b398a71f8b492210e4a401c7 359 Gene3D G3DSA:3.40.80.10 2 161 3.2E-42 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS10500 66999a90b398a71f8b492210e4a401c7 359 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 142 1.7E-25 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS10500 66999a90b398a71f8b492210e4a401c7 359 SUPERFAMILY SSF158634 177 224 3.4E-8 T 28-03-2018 A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 7.0E-93 T 28-03-2018 A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 Pfam PF04204 Homoserine O-succinyltransferase 2 299 8.4E-134 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 PIRSF PIRSF000450 1 302 9.2E-142 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 SUPERFAMILY SSF52317 17 297 3.21E-95 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 3.7E-128 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 Gene3D G3DSA:3.40.50.880 34 301 1.8E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS07545 903656e9810292b363c73c3473afa9d7 302 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 52.185 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 SUPERFAMILY SSF51905 1 193 4.25E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 SUPERFAMILY SSF51905 356 414 4.25E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 Gene3D G3DSA:3.50.50.60 1 421 6.8E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 Pfam PF03486 HI0933-like protein 3 410 4.2E-145 T 28-03-2018 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 SUPERFAMILY SSF160996 192 359 7.85E-45 T 28-03-2018 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.9E-9 T 28-03-2018 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 1.9E-9 T 28-03-2018 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 410 2.5E-138 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.7E-6 T 28-03-2018 A21D_RS14230 c27e511cb88db9d442337d8a38ba4d55 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.7E-6 T 28-03-2018 A21D_RS01855 2ba23bf8079d5c359f9c3463e63fe416 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 257 4.0E-72 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS01855 2ba23bf8079d5c359f9c3463e63fe416 258 Gene3D G3DSA:3.90.226.10 3 218 3.2E-63 T 28-03-2018 A21D_RS01855 2ba23bf8079d5c359f9c3463e63fe416 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS01855 2ba23bf8079d5c359f9c3463e63fe416 258 SUPERFAMILY SSF52096 3 257 4.12E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS01855 2ba23bf8079d5c359f9c3463e63fe416 258 Gene3D G3DSA:1.10.12.10 219 256 1.4E-18 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 SMART SM00116 344 390 1.2 T 28-03-2018 IPR000644 CBS domain A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 SMART SM00116 282 331 1.6 T 28-03-2018 IPR000644 CBS domain A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 SUPERFAMILY SSF54631 274 390 1.39E-16 T 28-03-2018 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 Gene3D G3DSA:3.10.580.10 263 393 1.1E-19 T 28-03-2018 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 391 1.2E-153 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 Pfam PF00005 ABC transporter 45 192 4.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 Gene3D G3DSA:3.40.50.300 2 262 8.4E-74 T 28-03-2018 A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 SMART SM00382 53 242 3.7E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 Pfam PF00571 CBS domain 338 389 0.0013 T 28-03-2018 IPR000644 CBS domain A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 Pfam PF00571 CBS domain 279 326 8.8E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS13100 389468aefda8f46e5cb3c21cfc3bca5b 399 SUPERFAMILY SSF52540 33 270 5.0E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 SUPERFAMILY SSF161070 6 445 1.7E-129 T 28-03-2018 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 298 317 4.1E-11 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 4.1E-11 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 4.1E-11 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 Pfam PF00209 Sodium:neurotransmitter symporter family 6 120 1.1E-24 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS11455 993192fdd51120c0eee7bd2c2510b109 448 Pfam PF00209 Sodium:neurotransmitter symporter family 152 442 1.9E-35 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SUPERFAMILY SSF48452 261 378 2.85E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 Pfam PF03704 Bacterial transcriptional activator domain 256 367 3.6E-5 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 Pfam PF00072 Response regulator receiver domain 10 118 1.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SMART SM00448 7 118 2.6E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 Gene3D G3DSA:3.40.50.2300 6 131 7.3E-26 T 28-03-2018 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SUPERFAMILY SSF46894 143 229 2.01E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SMART SM01043 236 375 0.0023 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 223 1.7E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SMART SM00862 153 229 9.4E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 SUPERFAMILY SSF52172 7 122 5.41E-27 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS01780 f7e27778a2b302700d77f141a081ff43 383 Gene3D G3DSA:1.10.10.10 132 232 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09580 dd1bab94e75e2ac6ffe53ed7eadc4f6a 625 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 33 624 1.6E-206 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 A21D_RS09580 dd1bab94e75e2ac6ffe53ed7eadc4f6a 625 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 32 624 2.1E-197 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 A21D_RS09580 dd1bab94e75e2ac6ffe53ed7eadc4f6a 625 Gene3D G3DSA:3.20.70.20 38 606 2.3E-204 T 28-03-2018 A21D_RS09580 dd1bab94e75e2ac6ffe53ed7eadc4f6a 625 SUPERFAMILY SSF51998 34 603 4.58E-157 T 28-03-2018 A21D_RS08085 48a42adbe06c08b36ff3ef2550a922a8 313 SUPERFAMILY SSF55909 7 313 4.1E-47 T 28-03-2018 A21D_RS08085 48a42adbe06c08b36ff3ef2550a922a8 313 Pfam PF02274 Amidinotransferase 45 312 4.7E-17 T 28-03-2018 A21D_RS08085 48a42adbe06c08b36ff3ef2550a922a8 313 Gene3D G3DSA:3.75.10.10 7 313 8.2E-41 T 28-03-2018 A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 SUPERFAMILY SSF46785 85 159 2.47E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 SUPERFAMILY SSF46785 3 81 3.06E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 PIRSF PIRSF019345 2 195 6.5E-59 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 Hamap MF_01804 Segregation and condensation protein B [scpB]. 3 183 34.102 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 191 1.0E-54 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 168 2.0E-57 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 Gene3D G3DSA:1.10.10.10 1 85 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16400 d57962d1113160770416b7fdbf685f88 196 Gene3D G3DSA:1.10.10.10 86 176 1.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19280 223689719eff3cfec23f3d26c5e221ee 371 Gene3D G3DSA:3.90.350.10 83 310 7.4E-26 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS19280 223689719eff3cfec23f3d26c5e221ee 371 SUPERFAMILY SSF53098 117 359 8.34E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS19280 223689719eff3cfec23f3d26c5e221ee 371 Pfam PF14294 Domain of unknown function (DUF4372) 7 75 3.4E-10 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS19280 223689719eff3cfec23f3d26c5e221ee 371 Pfam PF01609 Transposase DDE domain 122 329 1.4E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS11245 223689719eff3cfec23f3d26c5e221ee 371 Gene3D G3DSA:3.90.350.10 83 310 7.4E-26 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS11245 223689719eff3cfec23f3d26c5e221ee 371 SUPERFAMILY SSF53098 117 359 8.34E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS11245 223689719eff3cfec23f3d26c5e221ee 371 Pfam PF14294 Domain of unknown function (DUF4372) 7 75 3.4E-10 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS11245 223689719eff3cfec23f3d26c5e221ee 371 Pfam PF01609 Transposase DDE domain 122 329 1.4E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Gene3D G3DSA:3.60.20.10 22 450 2.3E-163 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 SUPERFAMILY SSF51395 459 1218 1.88E-264 T 28-03-2018 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 SUPERFAMILY SSF56235 22 445 5.19E-157 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Gene3D G3DSA:3.20.20.70 797 1235 8.8E-161 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Pfam PF01493 GXGXG motif 1263 1449 1.7E-81 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Pfam PF01645 Conserved region in glutamate synthase 813 1182 3.5E-155 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Pfam PF04898 Glutamate synthase central domain 470 753 1.0E-113 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Gene3D G3DSA:2.160.20.60 1237 1511 1.9E-109 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Pfam PF00310 Glutamine amidotransferases class-II 22 443 1.4E-186 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 SUPERFAMILY SSF69336 1232 1497 6.41E-93 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A21D_RS08760 59e3e82e36ab903761e5cd1048d73dea 1533 Gene3D G3DSA:3.20.20.70 451 796 6.9E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 199 242 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 SUPERFAMILY SSF46689 145 195 2.42E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 SUPERFAMILY SSF51215 9 132 4.05E-6 T 28-03-2018 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 SMART SM00342 162 246 9.1E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 Gene3D G3DSA:1.10.10.60 142 198 7.0E-12 T 28-03-2018 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 Gene3D G3DSA:1.10.10.60 199 251 8.4E-12 T 28-03-2018 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 215 230 4.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 246 4.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 SUPERFAMILY SSF46689 199 248 2.02E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 Pfam PF12833 Helix-turn-helix domain 168 247 5.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS00795 a91f25ef152f61462741c2dc2acd4a84 252 Gene3D G3DSA:2.60.120.280 3 137 3.3E-10 T 28-03-2018 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 258 275 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 493 238.089 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 PIRSF PIRSF006005 1 493 6.5E-211 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 7 492 8.4E-199 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 20 229 5.3E-34 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A21D_RS01360 fc6fddeabbf4c25c1079fcfab6c79024 493 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 246 439 9.1E-33 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 SUPERFAMILY SSF52402 4 186 2.51E-44 T 28-03-2018 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 Pfam PF01012 Electron transfer flavoprotein domain 7 179 1.7E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 Gene3D G3DSA:3.40.50.1220 195 325 5.7E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 199 282 5.7E-35 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 263 289 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 SMART SM00893 5 196 7.6E-37 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 PIRSF PIRSF000089 2 324 2.1E-109 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 SUPERFAMILY SSF52467 199 318 5.27E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS14805 2bd46dab6bbc0bae275b1a6dd383dd25 328 Gene3D G3DSA:3.40.50.620 3 192 1.2E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 4.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 4.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 4.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 Gene3D G3DSA:3.30.565.10 327 480 1.6E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 319 2.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SUPERFAMILY SSF47384 242 320 8.83E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 Gene3D G3DSA:1.10.287.130 249 320 3.2E-15 T 28-03-2018 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SMART SM00304 199 251 2.1E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SUPERFAMILY SSF158472 200 250 2.48E-8 T 28-03-2018 A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 477 5.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SMART SM00387 367 480 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SUPERFAMILY SSF55874 335 476 5.24E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07060 08dfcda38b4a5e183773281df4c9bcbe 481 SMART SM00388 259 325 3.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS06405 7fd255f8d88c12d846229a6318913834 84 SUPERFAMILY SSF55315 5 83 2.5E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS06405 7fd255f8d88c12d846229a6318913834 84 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 84 3.0E-16 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A21D_RS06405 7fd255f8d88c12d846229a6318913834 84 Gene3D G3DSA:3.30.1330.30 2 84 2.0E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 Gene3D G3DSA:2.30.330.10 237 331 1.1E-17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 SUPERFAMILY SSF103039 47 232 7.59E-27 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 Pfam PF02154 Flagellar motor switch protein FliM 40 230 2.4E-71 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 Gene3D G3DSA:3.40.1550.10 48 236 2.0E-45 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 3.9E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 3.9E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 3.9E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 3.9E-28 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 2.2E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 PIRSF PIRSF002888 2 332 9.4E-112 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 324 2.8E-107 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A21D_RS17890 2a450e4c29f6af8d28f96afe8bc4b2b0 332 SUPERFAMILY SSF101801 251 328 1.44E-13 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 8.9E-15 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 Gene3D G3DSA:2.10.260.10 1 37 9.8E-20 T 28-03-2018 A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.9E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 Gene3D G3DSA:3.30.450.40 38 178 3.3E-4 T 28-03-2018 IPR029016 GAF domain-like A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 SMART SM00966 8 52 3.8E-10 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 SUPERFAMILY SSF55781 82 177 6.38E-6 T 28-03-2018 IPR029016 GAF domain-like A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 SUPERFAMILY SSF89447 1 52 1.31E-14 T 28-03-2018 A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 178 9.3E-88 T 28-03-2018 IPR014213 Sporulation stage V, protein T A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 PIRSF PIRSF026579 1 178 7.7E-89 T 28-03-2018 IPR014213 Sporulation stage V, protein T A21D_RS06730 a2c312270afd5076d6a01ef39c43da0f 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 178 3.3E-43 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 Gene3D G3DSA:3.40.630.10 1 304 5.2E-53 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 Pfam PF01546 Peptidase family M20/M25/M40 108 421 1.4E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 Pfam PF07687 Peptidase dimerisation domain 226 314 3.2E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 SUPERFAMILY SSF55031 221 329 1.19E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 Gene3D G3DSA:3.40.630.10 305 429 9.1E-13 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 SUPERFAMILY SSF53187 4 48 1.08E-64 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 SUPERFAMILY SSF53187 88 236 1.08E-64 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 SUPERFAMILY SSF53187 335 427 1.08E-64 T 28-03-2018 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 411 1.7E-100 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS10705 d7aa870a1af708542cb6ace012c4edf7 431 PIRSF PIRSF005962 1 429 2.2E-110 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS02140 76ffa3093f5c268fb10016e3113c3ed5 195 Pfam PF12389 Camelysin metallo-endopeptidase 3 193 1.9E-87 T 28-03-2018 IPR022121 Peptidase M73, camelysin A21D_RS02140 76ffa3093f5c268fb10016e3113c3ed5 195 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 8.6E-11 T 28-03-2018 IPR023833 Signal peptide, camelysin A21D_RS02140 76ffa3093f5c268fb10016e3113c3ed5 195 Gene3D G3DSA:2.60.40.10 44 181 7.5E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS13060 a34fb92faa33c115cf190d65a030bdba 188 Gene3D G3DSA:1.10.10.10 9 152 1.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13060 a34fb92faa33c115cf190d65a030bdba 188 PIRSF PIRSF006707 9 188 3.0E-49 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type A21D_RS13060 a34fb92faa33c115cf190d65a030bdba 188 SUPERFAMILY SSF46785 21 171 1.51E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02960 0485a8a09b76f2dd370b31833293eaae 326 SUPERFAMILY SSF55347 126 291 1.47E-24 T 28-03-2018 A21D_RS02960 0485a8a09b76f2dd370b31833293eaae 326 Gene3D G3DSA:3.40.50.720 1 133 1.4E-35 T 28-03-2018 A21D_RS02960 0485a8a09b76f2dd370b31833293eaae 326 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 4.1E-27 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A21D_RS02960 0485a8a09b76f2dd370b31833293eaae 326 SUPERFAMILY SSF51735 2 151 2.21E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02960 0485a8a09b76f2dd370b31833293eaae 326 Gene3D G3DSA:3.30.360.10 134 326 4.5E-24 T 28-03-2018 A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 Gene3D G3DSA:3.90.76.10 66 228 9.7E-39 T 28-03-2018 A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 SUPERFAMILY SSF53850 57 553 2.53E-150 T 28-03-2018 A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 PIRSF PIRSF002741 5 557 1.1E-137 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 Gene3D G3DSA:3.40.190.10 229 323 3.2E-32 T 28-03-2018 A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 477 1.3E-105 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS03550 6ab5247ef2eb0036bbd0f9ba5c670f47 560 Gene3D G3DSA:3.10.105.10 324 530 3.8E-61 T 28-03-2018 A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 Gene3D G3DSA:3.20.20.70 13 352 1.6E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 Pfam PF13353 4Fe-4S single cluster domain 32 109 7.5E-7 T 28-03-2018 A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 Pfam PF04055 Radical SAM superfamily 28 176 5.8E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 1 361 7.5E-191 T 28-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 SUPERFAMILY SSF102114 24 318 2.88E-31 T 28-03-2018 A21D_RS03805 d22dca9beb02d564d99e67df34f73431 365 Pfam PF08756 YfkB-like domain 211 361 2.6E-74 T 28-03-2018 IPR014866 YfkB-like domain A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 SUPERFAMILY SSF47413 2 58 1.97E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 SUPERFAMILY SSF51182 66 169 6.61E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 Pfam PF01381 Helix-turn-helix 2 52 1.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 SMART SM00530 1 52 1.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 Gene3D G3DSA:1.10.260.40 1 55 1.9E-15 T 28-03-2018 A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 Pfam PF07883 Cupin domain 111 169 2.8E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel A21D_RS12685 1d69a79d1d53981e7a302d014d26face 174 Gene3D G3DSA:2.60.120.10 56 174 4.8E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS10460 c9e6db9a68b5fee2d89778bc804f08b5 323 SUPERFAMILY SSF69279 44 135 1.7E-7 T 28-03-2018 A21D_RS02275 aacc53d58e8a7aa8f7d8eacfc64b497e 625 SUPERFAMILY SSF51445 90 402 1.31E-50 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS02275 aacc53d58e8a7aa8f7d8eacfc64b497e 625 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 92 275 5.4E-11 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A21D_RS02275 aacc53d58e8a7aa8f7d8eacfc64b497e 625 Gene3D G3DSA:3.20.20.80 86 402 3.2E-58 T 28-03-2018 A21D_RS02275 aacc53d58e8a7aa8f7d8eacfc64b497e 625 Gene3D G3DSA:1.20.120.670 407 624 1.7E-73 T 28-03-2018 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 Gene3D G3DSA:3.40.190.10 176 258 1.9E-11 T 28-03-2018 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 Gene3D G3DSA:1.10.10.10 1 86 5.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 Pfam PF03466 LysR substrate binding domain 86 283 2.2E-39 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 5.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 SUPERFAMILY SSF46785 2 109 1.82E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 SUPERFAMILY SSF53850 87 284 1.33E-34 T 28-03-2018 A21D_RS05110 a253fd31033c753bbbb326263705d92b 289 Gene3D G3DSA:3.40.190.10 87 175 2.3E-15 T 28-03-2018 A21D_RS12495 16d172e540f573799abfdc10847f47e9 476 Pfam PF03553 Na+/H+ antiporter family 162 454 3.2E-58 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS12495 16d172e540f573799abfdc10847f47e9 476 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 11 458 1.3E-140 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A21D_RS11905 09ee50769931194aaa4fa53ffc6a7bb7 228 SUPERFAMILY SSF56214 100 211 6.28E-23 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS11905 09ee50769931194aaa4fa53ffc6a7bb7 228 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 101 202 6.6E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS11905 09ee50769931194aaa4fa53ffc6a7bb7 228 Gene3D G3DSA:3.90.470.20 111 205 1.5E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS11905 09ee50769931194aaa4fa53ffc6a7bb7 228 SUPERFAMILY SSF56214 4 94 1.83E-21 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS11905 09ee50769931194aaa4fa53ffc6a7bb7 228 Gene3D G3DSA:3.90.470.20 2 110 6.9E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A21D_RS03340 060c37f3afdab18dc846a849ac3e7b13 497 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 490 1.1E-159 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS03340 060c37f3afdab18dc846a849ac3e7b13 497 ProSitePatterns PS01303 BCCT family of transporters signature. 311 320 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS03340 060c37f3afdab18dc846a849ac3e7b13 497 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 489 1.3E-184 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PIRSF PIRSF001529 1 424 1.8E-192 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 4.6E-34 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 43.647 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 SUPERFAMILY SSF46589 1 113 4.66E-32 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 4.0E-181 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 Gene3D G3DSA:1.10.287.40 2 105 6.1E-28 T 28-03-2018 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 SUPERFAMILY SSF55681 117 422 1.91E-104 T 28-03-2018 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 5.0E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 2.4E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.4E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.4E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.4E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 2.4E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A21D_RS07165 3d203ea29c507675e5d953aecf7f1d95 424 Gene3D G3DSA:3.30.930.10 106 424 3.2E-100 T 28-03-2018 A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 SUPERFAMILY SSF50104 1 99 3.27E-39 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 Gene3D G3DSA:2.30.30.30 1 91 7.4E-38 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 SMART SM00739 2 29 2.8E-7 T 28-03-2018 IPR005824 KOW A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 1.3E-30 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 22.573 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 Pfam PF00467 KOW motif 5 36 2.3E-10 T 28-03-2018 IPR005824 KOW A21D_RS06320 fc523dd5b490f60f2575c19ce5ae82a2 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 6.6E-41 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 PIRSF PIRSF005902 1 255 3.0E-86 T 28-03-2018 IPR001130 TatD family GO:0016788 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 SUPERFAMILY SSF51556 2 254 3.15E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 9.8E-97 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 Gene3D G3DSA:3.20.20.140 1 255 1.5E-91 T 28-03-2018 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A21D_RS06810 6912cb5527a15a3cd84cc0a5ecc040ba 255 Pfam PF01026 TatD related DNase 3 252 9.5E-87 T 28-03-2018 IPR001130 TatD family GO:0016788 A21D_RS06830 4d21e489e13e7fb9e0056d1e9e72c6fd 98 Pfam PF01541 GIY-YIG catalytic domain 4 74 4.9E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS06830 4d21e489e13e7fb9e0056d1e9e72c6fd 98 SUPERFAMILY SSF82771 3 75 6.67E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS06830 4d21e489e13e7fb9e0056d1e9e72c6fd 98 Gene3D G3DSA:3.40.1440.10 1 83 1.7E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS06830 4d21e489e13e7fb9e0056d1e9e72c6fd 98 SMART SM00465 4 83 5.4E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS06980 f642a885f194737ba43e05f06af1c736 320 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 21 308 1.5E-9 T 28-03-2018 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 A21D_RS06980 f642a885f194737ba43e05f06af1c736 320 SMART SM00752 10 289 1.6E-39 T 28-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 SUPERFAMILY SSF55785 18 126 1.4E-23 T 28-03-2018 IPR000014 PAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 Gene3D G3DSA:3.30.750.24 149 259 6.1E-10 T 28-03-2018 IPR002645 STAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 SMART SM00086 85 127 2.3E-5 T 28-03-2018 IPR001610 PAC motif A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 Pfam PF01740 STAS domain 149 250 3.3E-6 T 28-03-2018 IPR002645 STAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 Gene3D G3DSA:3.30.450.20 1 141 1.3E-25 T 28-03-2018 A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 SMART SM00091 10 79 3.3E-4 T 28-03-2018 IPR000014 PAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 Pfam PF13426 PAS domain 30 126 5.6E-21 T 28-03-2018 IPR000014 PAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 SUPERFAMILY SSF52091 146 257 4.71E-14 T 28-03-2018 IPR002645 STAS domain A21D_RS19335 9c45f742d81a0a990867ee6183b6c42a 260 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 133 2.6E-18 T 28-03-2018 IPR000014 PAS domain A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 Pfam PF12833 Helix-turn-helix domain 21 99 1.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 SMART SM00871 122 279 9.8E-37 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 SMART SM00342 15 98 1.1E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 SUPERFAMILY SSF46689 51 110 9.86E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 Gene3D G3DSA:1.10.10.60 53 107 2.4E-9 T 28-03-2018 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 Gene3D G3DSA:1.10.10.60 3 52 5.8E-11 T 28-03-2018 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 52 94 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 Pfam PF06445 GyrI-like small molecule binding domain 122 279 7.5E-27 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 SUPERFAMILY SSF46689 5 49 2.2E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 Gene3D G3DSA:3.20.80.10 108 279 5.9E-48 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain A21D_RS05100 c9a4fc19d9acabfb4a7f37f565e53838 279 SUPERFAMILY SSF55136 122 279 3.14E-31 T 28-03-2018 A21D_RS06525 936154ad03a3710b321fb16d9f100838 155 PIRSF PIRSF010607 1 154 1.3E-65 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 A21D_RS06525 936154ad03a3710b321fb16d9f100838 155 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 1.3E-57 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 A21D_RS06525 936154ad03a3710b321fb16d9f100838 155 Gene3D G3DSA:1.10.10.10 1 67 0.039 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06525 936154ad03a3710b321fb16d9f100838 155 Gene3D G3DSA:1.10.10.10 68 118 0.16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.7E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.7E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.7E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.5E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 81 6.8E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 SUPERFAMILY SSF55594 3 82 1.31E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 Gene3D G3DSA:3.30.1340.10 1 82 2.0E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS00645 e6b61d398e0664ca24bbcff9588edc23 84 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A21D_RS16520 a117e2a4914fc9ade8ffc991870133d3 228 Gene3D G3DSA:2.40.10.220 100 216 1.2E-15 T 28-03-2018 A21D_RS16520 a117e2a4914fc9ade8ffc991870133d3 228 Pfam PF07238 PilZ domain 100 208 3.1E-8 T 28-03-2018 IPR009875 PilZ domain GO:0035438 A21D_RS16520 a117e2a4914fc9ade8ffc991870133d3 228 Pfam PF12945 Flagellar protein YcgR 2 93 1.8E-14 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal A21D_RS16520 a117e2a4914fc9ade8ffc991870133d3 228 Gene3D G3DSA:2.30.110.10 1 99 1.1E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 326 7.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 3.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 3.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 3.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 3.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 Gene3D G3DSA:3.30.565.10 174 326 8.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 SUPERFAMILY SSF55874 161 326 5.76E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS06095 e37ce6b1c403efa161bcd96a8e64e1cb 333 SMART SM00387 216 328 3.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS18905 1577f7432c1f7eaa51d9c6044a518edc 178 SUPERFAMILY SSF101874 6 177 3.66E-55 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A21D_RS18905 1577f7432c1f7eaa51d9c6044a518edc 178 SMART SM00867 5 175 1.6E-68 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A21D_RS18905 1577f7432c1f7eaa51d9c6044a518edc 178 Gene3D G3DSA:2.40.128.110 1 178 1.9E-54 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A21D_RS18905 1577f7432c1f7eaa51d9c6044a518edc 178 Pfam PF04264 YceI-like domain 6 174 1.1E-43 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A21D_RS05825 c1c27e229a81b444f78a219d9df2c1dc 254 PIRSF PIRSF030150 4 252 4.7E-93 T 28-03-2018 IPR015986 Sortase B, Firmicutes A21D_RS05825 c1c27e229a81b444f78a219d9df2c1dc 254 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 8 246 5.8E-87 T 28-03-2018 IPR009835 Sortase B family A21D_RS05825 c1c27e229a81b444f78a219d9df2c1dc 254 SUPERFAMILY SSF63817 18 250 9.94E-78 T 28-03-2018 IPR023365 Sortase domain A21D_RS05825 c1c27e229a81b444f78a219d9df2c1dc 254 Pfam PF04203 Sortase family 85 250 2.8E-25 T 28-03-2018 IPR005754 Sortase family A21D_RS05825 c1c27e229a81b444f78a219d9df2c1dc 254 Gene3D G3DSA:2.40.260.10 66 251 2.4E-66 T 28-03-2018 IPR023365 Sortase domain A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SUPERFAMILY SSF158472 185 235 3.92E-12 T 28-03-2018 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 Gene3D G3DSA:1.10.287.130 228 298 7.1E-17 T 28-03-2018 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SUPERFAMILY SSF47384 221 303 6.08E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SMART SM00304 185 237 1.0E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 458 3.8E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 2.2E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SMART SM00387 348 459 2.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 Pfam PF00672 HAMP domain 185 234 8.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SMART SM00388 238 304 3.4E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 9.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 9.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 9.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 9.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 SUPERFAMILY SSF55874 294 457 3.8E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS05290 07ac877a6d01c9e763170f521c281517 459 Gene3D G3DSA:3.30.565.10 299 458 2.6E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 SUPERFAMILY SSF52021 2 140 5.49E-51 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 SUPERFAMILY SSF52317 151 354 6.97E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00097 Anthranilate synthase component II signature 213 222 2.0E-7 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00097 Anthranilate synthase component II signature 240 251 2.0E-7 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00097 Anthranilate synthase component II signature 326 339 2.0E-7 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 Pfam PF00117 Glutamine amidotransferase class-I 173 349 9.7E-45 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 Gene3D G3DSA:3.40.50.880 143 356 2.3E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 131 1.5E-48 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 Gene3D G3DSA:3.50.30.20 1 142 9.8E-55 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 6.2E-33 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 6.2E-33 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 6.2E-33 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 6.2E-33 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 6.2E-33 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 SMART SM01097 2 132 2.2E-70 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 355 43.297 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 9.4E-12 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 9.4E-12 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 326 339 9.4E-12 T 28-03-2018 A21D_RS12790 44b258e2badbc6ecc0fca2e73725d6c9 363 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 352 6.8E-135 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS10180 78606e96d61f1d1eb70901cbf8862cd8 231 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 1.8E-51 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A21D_RS10180 78606e96d61f1d1eb70901cbf8862cd8 231 Pfam PF00814 Glycoprotease family 33 148 3.9E-32 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10180 78606e96d61f1d1eb70901cbf8862cd8 231 Gene3D G3DSA:3.30.420.40 1 138 1.2E-32 T 28-03-2018 A21D_RS10180 78606e96d61f1d1eb70901cbf8862cd8 231 SUPERFAMILY SSF53067 1 104 7.77E-30 T 28-03-2018 A21D_RS10180 78606e96d61f1d1eb70901cbf8862cd8 231 SUPERFAMILY SSF53067 108 214 4.66E-9 T 28-03-2018 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 808 2.1E-262 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SMART SM00874 411 479 3.8E-21 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SUPERFAMILY SSF46955 412 483 5.86E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Pfam PF03147 Ferredoxin-fold anticodon binding domain 715 808 1.9E-29 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SMART SM00873 221 394 1.8E-84 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 802 45.478 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SUPERFAMILY SSF56037 208 405 4.71E-70 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Pfam PF03483 B3/4 domain 222 393 2.7E-64 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:3.30.70.380 711 808 5.5E-27 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SUPERFAMILY SSF50249 36 199 3.67E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:3.30.56.10 409 483 4.3E-20 T 28-03-2018 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Pfam PF01588 Putative tRNA binding domain 46 152 1.3E-28 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SMART SM00896 715 808 2.1E-41 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:3.30.930.10 497 702 2.8E-30 T 28-03-2018 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Pfam PF03484 tRNA synthetase B5 domain 414 479 8.9E-16 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:3.30.56.10 1 54 1.3E-14 T 28-03-2018 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SUPERFAMILY SSF55681 475 702 2.29E-45 T 28-03-2018 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:3.50.40.10 204 405 3.6E-69 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 SUPERFAMILY SSF54991 710 808 6.67E-31 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A21D_RS14750 f88a186f27495fa96d843a35cd231769 809 Gene3D G3DSA:2.40.50.140 55 161 8.8E-45 T 28-03-2018 A21D_RS00495 eda00ef1915f2fc658ba61fc75eada1e 96 Pfam PF01910 Thiamine-binding protein 6 93 2.3E-22 T 28-03-2018 IPR002767 Thiamine-binding protein A21D_RS00495 eda00ef1915f2fc658ba61fc75eada1e 96 SUPERFAMILY SSF89957 2 95 1.57E-23 T 28-03-2018 IPR029756 MTH1187/YkoF-like A21D_RS00495 eda00ef1915f2fc658ba61fc75eada1e 96 Gene3D G3DSA:3.30.70.930 1 96 2.0E-21 T 28-03-2018 IPR029756 MTH1187/YkoF-like A21D_RS06515 e7172b8e02e7348736b5f1a0318130ae 354 SUPERFAMILY SSF55931 3 269 3.08E-85 T 28-03-2018 A21D_RS06515 e7172b8e02e7348736b5f1a0318130ae 354 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 37.11 T 28-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 A21D_RS06515 e7172b8e02e7348736b5f1a0318130ae 354 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 28-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 A21D_RS06515 e7172b8e02e7348736b5f1a0318130ae 354 Gene3D G3DSA:3.30.590.10 4 256 7.8E-85 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A21D_RS06515 e7172b8e02e7348736b5f1a0318130ae 354 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 69 253 4.2E-72 T 28-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Pfam PF00874 PRD domain 177 268 2.6E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Pfam PF00874 PRD domain 71 157 4.0E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 SUPERFAMILY SSF63520 169 269 2.88E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Gene3D G3DSA:1.10.1790.10 60 163 1.7E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 SUPERFAMILY SSF50151 2 53 4.45E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 SUPERFAMILY SSF63520 51 160 6.67E-28 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 SMART SM01061 1 59 5.4E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Gene3D G3DSA:1.10.1790.10 165 272 3.9E-25 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Pfam PF03123 CAT RNA binding domain 2 54 3.3E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS08450 0a38058c3ef590c1a7dc83bf52b66ce1 273 Gene3D G3DSA:2.30.24.10 2 52 4.5E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 Gene3D G3DSA:3.30.230.10 8 178 8.7E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 103 114 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 SUPERFAMILY SSF54211 15 195 2.13E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 PRINTS PR00959 Mevalonate kinase family signature 17 41 1.5E-21 T 28-03-2018 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 PRINTS PR00959 Mevalonate kinase family signature 274 291 1.5E-21 T 28-03-2018 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 PRINTS PR00959 Mevalonate kinase family signature 144 163 1.5E-21 T 28-03-2018 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 PRINTS PR00959 Mevalonate kinase family signature 101 123 1.5E-21 T 28-03-2018 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 18 289 1.1E-84 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 Gene3D G3DSA:3.30.70.890 180 318 1.5E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 SUPERFAMILY SSF55060 180 315 1.73E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 Pfam PF00288 GHMP kinases N terminal domain 97 160 5.5E-14 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A21D_RS05375 6f71a39b71ebca24359eab1cc3e1d62f 322 Pfam PF08544 GHMP kinases C terminal 228 307 2.3E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 SMART SM00382 30 245 5.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 Pfam PF00005 ABC transporter 21 179 1.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 SUPERFAMILY SSF52540 5 250 3.31E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 PIRSF PIRSF039085 2 256 1.2E-104 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A21D_RS02990 8e8d211afd4e47aefb71e596fb50c099 256 Gene3D G3DSA:3.40.50.300 1 255 1.8E-75 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 SUPERFAMILY SSF51905 201 505 1.23E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Gene3D G3DSA:3.40.50.720 204 330 7.3E-20 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Pfam PF13192 Thioredoxin domain 124 194 5.4E-9 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Gene3D G3DSA:3.40.30.10 102 196 2.0E-5 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 1.9E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 509 3.0E-242 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Gene3D G3DSA:3.50.50.60 436 509 1.9E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PIRSF PIRSF000238 2 509 1.1E-255 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Gene3D G3DSA:3.40.30.10 2 93 1.1E-23 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 487 4.1E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 SUPERFAMILY SSF52833 3 101 1.23E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 Gene3D G3DSA:3.50.50.60 331 435 6.3E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.0E-39 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.0E-39 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 1.0E-39 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 1.0E-39 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.0E-39 T 28-03-2018 A21D_RS09370 4b084e207daf1a09be78467dd66a3a75 509 SUPERFAMILY SSF52833 103 194 8.62E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 Gene3D G3DSA:3.40.50.720 2 173 4.1E-30 T 28-03-2018 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 226 3.8E-46 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 Gene3D G3DSA:3.90.25.10 174 303 1.4E-30 T 28-03-2018 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 PRINTS PR01713 Nucleotide sugar epimerase signature 197 212 2.0E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 PRINTS PR01713 Nucleotide sugar epimerase signature 220 235 2.0E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 PRINTS PR01713 Nucleotide sugar epimerase signature 266 283 2.0E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS08635 bb5cbdb6afe29092443d15ac5b986e23 308 SUPERFAMILY SSF51735 1 298 1.44E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18625 ed6cc6d06ad90004dd54d7b70e8cb3a2 89 PIRSF PIRSF037260 1 89 1.0E-33 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 A21D_RS18625 ed6cc6d06ad90004dd54d7b70e8cb3a2 89 SUPERFAMILY SSF158504 4 88 1.29E-29 T 28-03-2018 IPR023324 BH2638-like domain A21D_RS18625 ed6cc6d06ad90004dd54d7b70e8cb3a2 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 86 7.6E-32 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 A21D_RS18625 ed6cc6d06ad90004dd54d7b70e8cb3a2 89 Gene3D G3DSA:1.10.220.80 12 88 2.4E-27 T 28-03-2018 IPR023324 BH2638-like domain A21D_RS18625 ed6cc6d06ad90004dd54d7b70e8cb3a2 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 3 88 3.0E-26 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 Gene3D G3DSA:3.40.630.10 316 401 7.4E-16 T 28-03-2018 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 Gene3D G3DSA:3.40.630.10 9 288 5.0E-47 T 28-03-2018 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 SUPERFAMILY SSF53187 292 385 1.6E-57 T 28-03-2018 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 SUPERFAMILY SSF53187 13 192 1.6E-57 T 28-03-2018 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 SUPERFAMILY SSF55031 181 285 1.57E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 Pfam PF01546 Peptidase family M20/M25/M40 98 336 3.8E-7 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 346 7.5E-64 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 Pfam PF07687 Peptidase dimerisation domain 184 272 2.3E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS07145 d972b98b1fc20b2e0c0450b0b97c7492 401 PIRSF PIRSF037226 5 401 8.6E-163 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted A21D_RS03540 7f3114da302a16870b1e150a0ac51c00 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 309 7.1E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS03540 7f3114da302a16870b1e150a0ac51c00 311 SUPERFAMILY SSF161098 103 291 2.49E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS03540 7f3114da302a16870b1e150a0ac51c00 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 85 5.6E-14 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A21D_RS03540 7f3114da302a16870b1e150a0ac51c00 311 Gene3D G3DSA:1.10.3720.10 35 298 3.2E-50 T 28-03-2018 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 Pfam PF02272 DHHA1 domain 517 645 3.6E-14 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 SMART SM00267 146 298 4.3E-5 T 28-03-2018 IPR000160 GGDEF domain A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 Gene3D G3DSA:3.30.70.270 151 299 3.7E-5 T 28-03-2018 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 Pfam PF01368 DHH family 338 495 4.1E-22 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 SUPERFAMILY SSF64182 337 644 4.71E-70 T 28-03-2018 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 Gene3D G3DSA:3.90.1640.10 316 535 7.5E-46 T 28-03-2018 A21D_RS07355 7ce7914a1f4ced3ba290cfd27275d636 656 PIRSF PIRSF026583 1 656 1.1E-267 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 Gene3D G3DSA:2.40.290.10 1 181 1.4E-31 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 257 4.3E-94 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 PIRSF PIRSF006493 1 283 2.4E-105 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 178 5.5E-39 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 SMART SM00559 52 181 4.2E-45 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 32.514 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A21D_RS09200 2215d72eb1fb266552f51953db284f01 283 SUPERFAMILY SSF100939 2 259 5.69E-54 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain A21D_RS04590 9827ee9cc5486bccd2c17d39a634e231 391 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.1E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS04590 9827ee9cc5486bccd2c17d39a634e231 391 SUPERFAMILY SSF53098 62 342 6.98E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS04590 9827ee9cc5486bccd2c17d39a634e231 391 Pfam PF01609 Transposase DDE domain 126 329 1.9E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS04590 9827ee9cc5486bccd2c17d39a634e231 391 Gene3D G3DSA:3.90.350.10 177 310 1.1E-18 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 687 25.285 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 Gene3D G3DSA:1.10.3210.10 332 532 8.9E-5 T 28-03-2018 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 1.2E-34 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 1.2E-34 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.2E-34 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 1.2E-34 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 1.2E-34 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 Gene3D G3DSA:1.10.730.10 564 690 1.1E-6 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 SUPERFAMILY SSF109604 338 503 7.07E-20 T 28-03-2018 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 554 2.1E-197 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 Pfam PF05746 DALR anticodon binding domain 584 688 1.1E-7 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A21D_RS15745 4ae8c5072154dcf71365c29601708b2f 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 4 687 4.7E-223 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 SUPERFAMILY SSF52540 769 918 3.98E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 SUPERFAMILY SSF52540 607 681 3.98E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 Gene3D G3DSA:3.40.50.300 607 995 9.0E-47 T 28-03-2018 A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 SUPERFAMILY SSF52540 35 296 4.06E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 Gene3D G3DSA:3.40.50.300 14 400 6.7E-32 T 28-03-2018 A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 Pfam PF00350 Dynamin family 51 205 2.6E-26 T 28-03-2018 IPR022812 Dynamin superfamily A21D_RS17000 c131541c66d800d62fab325dc7db65bf 1212 Pfam PF00350 Dynamin family 631 856 2.3E-43 T 28-03-2018 IPR022812 Dynamin superfamily A21D_RS17455 e170ac43a20795038b29df849789bd10 215 SMART SM00530 6 62 3.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS17455 e170ac43a20795038b29df849789bd10 215 Gene3D G3DSA:2.10.109.10 87 214 3.5E-16 T 28-03-2018 A21D_RS17455 e170ac43a20795038b29df849789bd10 215 Pfam PF00717 Peptidase S24-like 126 182 1.9E-8 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS17455 e170ac43a20795038b29df849789bd10 215 SUPERFAMILY SSF51306 85 211 1.19E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS17455 e170ac43a20795038b29df849789bd10 215 Gene3D G3DSA:1.10.260.40 1 84 1.1E-17 T 28-03-2018 A21D_RS17455 e170ac43a20795038b29df849789bd10 215 Pfam PF01381 Helix-turn-helix 7 62 9.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS17455 e170ac43a20795038b29df849789bd10 215 SUPERFAMILY SSF47413 2 66 5.36E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 SUPERFAMILY SSF53901 4 270 4.24E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 PIRSF PIRSF000429 1 403 2.0E-126 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 399 3.3E-139 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 Pfam PF02803 Thiolase, C-terminal domain 272 400 6.2E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 Gene3D G3DSA:3.40.47.10 273 399 7.0E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 Gene3D G3DSA:3.40.47.10 1 272 7.2E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 SUPERFAMILY SSF53901 272 399 1.85E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS09225 eff4ae3868d87276cf2c1cdfdbe185dc 403 Pfam PF00108 Thiolase, N-terminal domain 4 263 3.1E-96 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 SUPERFAMILY SSF50249 5 86 2.83E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 PRINTS PR00681 Ribosomal protein S1 signature 60 78 1.2E-11 T 28-03-2018 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 PRINTS PR00681 Ribosomal protein S1 signature 21 40 1.2E-11 T 28-03-2018 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 Pfam PF00575 S1 RNA binding domain 5 77 1.0E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 Gene3D G3DSA:2.40.50.140 8 121 4.1E-28 T 28-03-2018 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 SMART SM00316 6 77 1.5E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 A21D_RS14015 c9adb2887c2c80b42966676b57ee5f65 121 Pfam PF02599 Global regulator protein family 49 82 2.1E-4 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 7.8E-12 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 Gene3D G3DSA:3.30.70.240 135 198 4.1E-16 T 28-03-2018 A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 7.1E-35 T 28-03-2018 IPR001498 Impact, N-terminal A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 SUPERFAMILY SSF54980 135 201 4.17E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 Gene3D G3DSA:3.30.230.30 4 133 5.4E-49 T 28-03-2018 IPR001498 Impact, N-terminal A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 200 5.1E-67 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal A21D_RS00925 5ba4e7015e30d381d83aa9bbdba7b6db 210 SUPERFAMILY SSF54211 3 131 1.56E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS04275 e455157607ce807767da18286346e764 418 PIRSF PIRSF500136 1 417 2.0E-155 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A21D_RS04275 e455157607ce807767da18286346e764 418 SUPERFAMILY SSF51735 1 192 7.0E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04275 e455157607ce807767da18286346e764 418 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 179 1.2E-55 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 SUPERFAMILY SSF48179 198 291 2.72E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS04275 e455157607ce807767da18286346e764 418 Gene3D G3DSA:1.20.5.170 198 221 5.4E-14 T 28-03-2018 A21D_RS04275 e455157607ce807767da18286346e764 418 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 397 4.7E-135 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 Gene3D G3DSA:3.40.50.720 1 197 2.7E-40 T 28-03-2018 A21D_RS04275 e455157607ce807767da18286346e764 418 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 285 1.8E-25 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 309 400 8.5E-22 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 Gene3D G3DSA:3.40.50.720 222 411 3.0E-55 T 28-03-2018 A21D_RS04275 e455157607ce807767da18286346e764 418 SMART SM00984 308 401 2.0E-24 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 PIRSF PIRSF000124 1 413 1.8E-79 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS04275 e455157607ce807767da18286346e764 418 SUPERFAMILY SSF52413 297 400 7.59E-26 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 SUPERFAMILY SSF53822 58 321 7.25E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 Gene3D G3DSA:3.40.50.2300 164 327 8.2E-40 T 28-03-2018 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 Gene3D G3DSA:3.40.50.2300 58 163 2.3E-26 T 28-03-2018 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 Pfam PF13377 Periplasmic binding protein-like domain 166 327 7.9E-32 T 28-03-2018 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.7E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 SUPERFAMILY SSF47413 2 59 7.88E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 Gene3D G3DSA:1.10.260.40 2 57 1.8E-23 T 28-03-2018 A21D_RS01670 0cdcd8ade61624a86e1e15dec4d2385d 327 SMART SM00354 1 71 3.6E-31 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 SUPERFAMILY SSF63520 60 169 7.72E-29 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 SUPERFAMILY SSF63520 176 275 3.79E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Gene3D G3DSA:2.30.24.10 1 58 2.6E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Gene3D G3DSA:1.10.1790.10 59 169 3.1E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Gene3D G3DSA:1.10.1790.10 170 279 1.1E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Pfam PF03123 CAT RNA binding domain 5 59 3.0E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Pfam PF00874 PRD domain 184 274 7.6E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 Pfam PF00874 PRD domain 79 166 1.3E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 SMART SM01061 4 62 1.1E-23 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS12385 6e93d899bc572bace4a22eee4eb9f920 281 SUPERFAMILY SSF50151 4 57 1.44E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A21D_RS19105 7e37fa3438e16bae57bd1d6ba0700084 33 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 9 32 6.0E-12 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS19105 7e37fa3438e16bae57bd1d6ba0700084 33 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 32 4.6E-13 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS14825 a934de8570408cdb2e7843ec77fb5666 204 SUPERFAMILY SSF81343 5 200 2.88E-59 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14825 a934de8570408cdb2e7843ec77fb5666 204 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 87 189 1.3E-12 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A21D_RS14825 a934de8570408cdb2e7843ec77fb5666 204 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 199 1.6E-48 T 28-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit A21D_RS14825 a934de8570408cdb2e7843ec77fb5666 204 PIRSF PIRSF000170 1 204 1.5E-95 T 28-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute A21D_RS14825 a934de8570408cdb2e7843ec77fb5666 204 Gene3D G3DSA:1.20.1300.10 2 203 3.3E-46 T 28-03-2018 A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 SMART SM00962 176 367 2.0E-57 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 SUPERFAMILY SSF52540 176 366 2.13E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 263 8.5E-67 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 SMART SM00382 175 330 1.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 Gene3D G3DSA:3.40.50.300 175 355 1.5E-21 T 28-03-2018 A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 Gene3D G3DSA:1.20.120.140 118 167 0.0033 T 28-03-2018 A21D_RS17845 4bcb5b7bdf6393d42c8b4a444844d5af 372 Pfam PF00448 SRP54-type protein, GTPase domain 177 366 1.2E-41 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 SUPERFAMILY SSF100950 72 230 6.59E-26 T 28-03-2018 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 Pfam PF08220 DeoR-like helix-turn-helix domain 5 60 2.4E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 SMART SM00420 5 57 9.8E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 Gene3D G3DSA:3.40.50.1360 76 237 3.1E-30 T 28-03-2018 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 Gene3D G3DSA:1.10.10.10 1 75 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 Pfam PF00455 DeoR C terminal sensor domain 72 229 2.0E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 SUPERFAMILY SSF46785 4 61 7.93E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 SMART SM01134 70 231 2.9E-53 T 28-03-2018 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 6.6E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS01985 98c8edb0cdca6de70b847720e42d80a8 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 6.6E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS10295 f8ff5d7c9da95bd970ee709f8d777d62 270 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 1 229 3.4E-82 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 A21D_RS10295 f8ff5d7c9da95bd970ee709f8d777d62 270 Pfam PF03837 RecT family 50 231 1.5E-50 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 A21D_RS16990 1c809cf2c09190d284d09baeeaa2d051 209 Gene3D G3DSA:3.40.50.300 9 206 5.2E-54 T 28-03-2018 A21D_RS16990 1c809cf2c09190d284d09baeeaa2d051 209 SUPERFAMILY SSF52540 18 203 5.03E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16990 1c809cf2c09190d284d09baeeaa2d051 209 SMART SM00382 22 205 6.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS16990 1c809cf2c09190d284d09baeeaa2d051 209 Pfam PF00005 ABC transporter 17 155 1.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS16990 1c809cf2c09190d284d09baeeaa2d051 209 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 SUPERFAMILY SSF53738 157 254 7.85E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Gene3D G3DSA:3.40.120.10 164 267 1.1E-29 T 28-03-2018 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Gene3D G3DSA:3.40.120.10 268 372 1.4E-35 T 28-03-2018 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 SUPERFAMILY SSF55957 356 445 6.28E-27 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 3.4E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Gene3D G3DSA:3.40.120.10 2 163 5.6E-43 T 28-03-2018 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 6.5E-187 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 441 1.0E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 SUPERFAMILY SSF53738 256 365 3.02E-34 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 45.286 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 SUPERFAMILY SSF53738 3 179 8.24E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 366 4.6E-35 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 1.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Gene3D G3DSA:3.30.310.50 373 445 7.4E-24 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS05300 ae137c017664072aa5b7bacacefd8a8f 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 252 6.1E-17 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A21D_RS15230 f399a558db5fa17d0f5c943d10a7587e 195 Gene3D G3DSA:1.10.287.130 19 73 5.2E-8 T 28-03-2018 A21D_RS15230 f399a558db5fa17d0f5c943d10a7587e 195 Gene3D G3DSA:3.30.565.30 77 187 6.8E-8 T 28-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A21D_RS15230 f399a558db5fa17d0f5c943d10a7587e 195 SUPERFAMILY SSF55890 21 139 9.68E-22 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A21D_RS15230 f399a558db5fa17d0f5c943d10a7587e 195 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 20 75 9.4E-14 T 28-03-2018 A21D_RS17240 57cdae55571fca7013b729a2f855c180 87 Pfam PF04531 Bacteriophage holin 3 84 2.6E-28 T 28-03-2018 IPR006485 Bacteriophage holin A21D_RS17240 57cdae55571fca7013b729a2f855c180 87 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 3 83 9.9E-22 T 28-03-2018 IPR006485 Bacteriophage holin A21D_RS15700 7941191c8fb46319ba041e89672e25ca 403 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 393 7.6E-110 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD A21D_RS15700 7941191c8fb46319ba041e89672e25ca 403 PIRSF PIRSF029895 1 403 2.2E-109 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD A21D_RS15700 7941191c8fb46319ba041e89672e25ca 403 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 9 393 5.0E-114 T 28-03-2018 IPR010690 Putative stage IV sporulation YqfD A21D_RS01505 7d9cea2a4732478d1fb6a941f89f9d2f 141 SUPERFAMILY SSF55729 17 133 2.34E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS01505 7d9cea2a4732478d1fb6a941f89f9d2f 141 Pfam PF13523 Acetyltransferase (GNAT) domain 17 113 1.8E-19 T 28-03-2018 A21D_RS01505 7d9cea2a4732478d1fb6a941f89f9d2f 141 Gene3D G3DSA:3.40.630.30 4 138 1.3E-19 T 28-03-2018 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 Gene3D G3DSA:1.20.58.180 206 282 1.5E-36 T 28-03-2018 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 289 1.4E-161 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 Gene3D G3DSA:3.30.930.10 1 204 1.2E-78 T 28-03-2018 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.664 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 7.3E-66 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 6.6E-147 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A21D_RS15740 cf43b647a8dfd1ab58d0592a7c96c9e0 292 SUPERFAMILY SSF55681 1 280 1.17E-129 T 28-03-2018 A21D_RS10615 aeba6c37c62583c9a02aeffd42143332 178 Pfam PF02517 CAAX protease self-immunity 81 170 7.3E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 Gene3D G3DSA:3.40.80.10 6 184 1.1E-34 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 Pfam PF08230 CW_7 repeat 200 237 1.1E-7 T 28-03-2018 IPR013168 Cpl-7 lysozyme, C-terminal A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 Pfam PF08230 CW_7 repeat 254 293 1.4E-7 T 28-03-2018 IPR013168 Cpl-7 lysozyme, C-terminal A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 SUPERFAMILY SSF55846 13 170 5.5E-32 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 SMART SM00644 19 153 1.5E-15 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 SMART SM01095 198 240 0.0099 T 28-03-2018 IPR013168 Cpl-7 lysozyme, C-terminal A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 SMART SM01095 252 294 2.2E-4 T 28-03-2018 IPR013168 Cpl-7 lysozyme, C-terminal A21D_RS19605 05fa68840c9e8622987ff544f8cf8d58 363 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 29 153 8.0E-19 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 SMART SM00866 91 232 7.2E-15 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 SUPERFAMILY SSF64288 56 238 1.88E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 Gene3D G3DSA:1.10.10.10 2 74 4.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 Pfam PF07702 UTRA domain 92 232 2.3E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 SUPERFAMILY SSF46785 6 77 1.63E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 SMART SM00345 9 68 9.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 2.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 Gene3D G3DSA:3.40.1410.10 75 241 2.3E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08215 0a7e39d8e3df03ec69b8c49ed850895c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS17080 91ebe8b3b0c80729ccb0cf6a8410bd50 74 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-19 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A21D_RS17080 91ebe8b3b0c80729ccb0cf6a8410bd50 74 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 74 2.2E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A21D_RS17080 91ebe8b3b0c80729ccb0cf6a8410bd50 74 SMART SM01234 1 68 7.4E-44 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A21D_RS17080 91ebe8b3b0c80729ccb0cf6a8410bd50 74 Pfam PF01809 Haemolytic domain 3 68 5.5E-29 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A21D_RS17080 91ebe8b3b0c80729ccb0cf6a8410bd50 74 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.225 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A21D_RS04765 e4573974439aebab68f5c4c470b856b6 297 Gene3D G3DSA:1.10.3720.10 11 290 2.5E-38 T 28-03-2018 A21D_RS04765 e4573974439aebab68f5c4c470b856b6 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 290 2.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04765 e4573974439aebab68f5c4c470b856b6 297 SUPERFAMILY SSF161098 9 296 1.74E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS06420 d647284bf880a14923e0e7bb8a8ed47e 200 Gene3D G3DSA:3.40.50.150 12 200 4.4E-29 T 28-03-2018 A21D_RS06420 d647284bf880a14923e0e7bb8a8ed47e 200 SUPERFAMILY SSF53335 9 199 4.56E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS06420 d647284bf880a14923e0e7bb8a8ed47e 200 Pfam PF05175 Methyltransferase small domain 28 196 9.3E-51 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 SUPERFAMILY SSF52540 5 250 1.45E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 SMART SM00382 35 236 1.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 Gene3D G3DSA:3.40.50.300 2 319 4.9E-86 T 28-03-2018 A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 4.1E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 Pfam PF00005 ABC transporter 27 178 6.2E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04480 3fc49fe3f7c8d0dad0471f829f0d0a2e 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 7.7E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 Gene3D G3DSA:3.30.70.1450 306 381 8.3E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 SUPERFAMILY SSF116726 207 284 7.06E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 Pfam PF02080 TrkA-C domain 219 276 6.6E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 SUPERFAMILY SSF116726 292 377 8.11E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 Pfam PF03600 Citrate transporter 23 535 1.9E-35 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 Gene3D G3DSA:3.30.70.1450 215 292 1.2E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS07485 8213315a2ba5f20f237718f0e31b78dd 592 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 541 557 - T 28-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 SUPERFAMILY SSF48498 76 189 2.58E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 Gene3D G3DSA:1.10.357.10 53 199 4.3E-20 T 28-03-2018 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 3.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 SUPERFAMILY SSF46689 3 81 3.39E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 Pfam PF08359 YsiA-like protein, C-terminal region 63 185 7.3E-5 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A21D_RS17040 7d5436e5e630bd86f64af1f1f8a5845a 209 Gene3D G3DSA:1.10.10.60 4 52 1.3E-14 T 28-03-2018 A21D_RS16735 73bd97b7de769db4ca6daff49cd9751e 55 Pfam PF14084 Protein of unknown function (DUF4264) 4 54 1.0E-21 T 28-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA A21D_RS16735 73bd97b7de769db4ca6daff49cd9751e 55 PIRSF PIRSF036698 1 55 2.4E-25 T 28-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 Pfam PF02378 Phosphotransferase system, EIIC 108 390 2.2E-31 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 SUPERFAMILY SSF51261 471 619 3.49E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 620 1.6E-201 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 Pfam PF00367 phosphotransferase system, EIIB 9 41 9.7E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 Gene3D G3DSA:3.30.1360.60 4 80 9.2E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 474 596 7.5E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 537 549 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 475 595 2.2E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 Gene3D G3DSA:2.70.70.10 461 622 8.0E-54 T 28-03-2018 A21D_RS10735 350c3ec7e48ce5b7531012fd3d0f8e66 622 SUPERFAMILY SSF55604 6 81 8.89E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS09145 b122edd2e312b66136ee4a9437ee8bb8 60 Gene3D G3DSA:1.20.120.330 2 60 3.7E-6 T 28-03-2018 A21D_RS03240 405c97ee90bc47b3a9647d55e5153cfa 210 Gene3D G3DSA:3.20.20.70 1 203 5.3E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03240 405c97ee90bc47b3a9647d55e5153cfa 210 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 198 5.6E-52 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A21D_RS03240 405c97ee90bc47b3a9647d55e5153cfa 210 SUPERFAMILY SSF51366 1 201 7.69E-52 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS03240 405c97ee90bc47b3a9647d55e5153cfa 210 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 203 36.444 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 SUPERFAMILY SSF53067 1 194 3.88E-71 T 28-03-2018 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PIRSF PIRSF000722 1 396 2.8E-153 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 Hamap MF_00020 Acetate kinase [ackA]. 1 396 191.787 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 Gene3D G3DSA:3.30.420.40 195 396 3.4E-80 T 28-03-2018 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 202 223 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 320 336 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 298 311 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 4 15 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 374 386 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 PRINTS PR00471 Acetate kinase family signature 172 185 4.7E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 Pfam PF00871 Acetokinase family 4 387 8.6E-168 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 4.2E-175 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 Gene3D G3DSA:3.30.420.40 3 194 1.1E-80 T 28-03-2018 A21D_RS14455 6dbabf43a8777fe8a166811cb506ab24 396 SUPERFAMILY SSF53067 157 393 1.87E-91 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:3.40.50.300 405 617 4.9E-22 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:3.30.190.20 140 247 1.2E-45 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:1.10.8.280 284 404 4.2E-37 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Pfam PF00005 ABC transporter 622 858 2.9E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.262 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 923 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:3.40.50.300 38 139 8.4E-4 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:3.40.50.300 618 951 3.5E-56 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 Gene3D G3DSA:3.40.50.300 8 37 0.0017 T 28-03-2018 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 SMART SM00382 631 906 0.01 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 SUPERFAMILY SSF52540 614 912 3.86E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 SUPERFAMILY SSF52540 6 206 4.5E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00735 901327a06ea47409a5d8f9fec5528594 958 SUPERFAMILY SSF52540 430 569 4.5E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 SMART SM00382 97 251 3.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 SUPERFAMILY SSF46785 13 60 5.52E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Pfam PF03610 PTS system fructose IIA component 511 621 5.5E-13 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 101 114 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Gene3D G3DSA:3.40.50.300 44 266 1.3E-28 T 28-03-2018 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Pfam PF00158 Sigma-54 interaction domain 96 239 3.3E-41 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Gene3D G3DSA:3.40.50.510 488 643 2.1E-24 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Gene3D G3DSA:1.10.8.60 267 338 1.9E-6 T 28-03-2018 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Gene3D G3DSA:1.10.10.10 2 43 3.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 Gene3D G3DSA:3.40.50.2300 644 740 2.2E-6 T 28-03-2018 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 SUPERFAMILY SSF53062 509 626 6.93E-17 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 170 185 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A21D_RS11250 4ceeaf29ccd193b3e85647e5415cb9f1 872 SUPERFAMILY SSF52540 68 334 8.32E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS19085 20dfacea7b805cb6dba10532869a4dc5 168 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 17 167 4.8E-26 T 28-03-2018 IPR018920 ESAT-6 secretion machinery protein EssA/YueC A21D_RS19085 20dfacea7b805cb6dba10532869a4dc5 168 Pfam PF10661 WXG100 protein secretion system (Wss), protein EssA 34 167 1.8E-33 T 28-03-2018 IPR034026 ESAT-6 secretion machinery protein EssA A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Gene3D G3DSA:1.10.10.10 1 62 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 SUPERFAMILY SSF50037 283 325 5.49E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Pfam PF02237 Biotin protein ligase C terminal domain 284 324 8.1E-6 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 323 7.1E-62 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Gene3D G3DSA:2.30.30.100 280 323 5.1E-7 T 28-03-2018 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 326 33.485 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 SUPERFAMILY SSF46785 2 60 2.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 SUPERFAMILY SSF55681 71 276 7.95E-57 T 28-03-2018 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Pfam PF08279 HTH domain 5 59 1.2E-17 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Pfam PF03099 Biotin/lipoate A/B protein ligase family 89 214 1.9E-15 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A21D_RS16725 c4e27e20fe5ca62c9bc7297b1aa1978d 334 Gene3D G3DSA:3.30.930.10 65 278 1.5E-60 T 28-03-2018 A21D_RS15590 c2b4566d0cac604b33aef97c93de3739 44 Pfam PF14141 YqzM-like protein 2 43 1.3E-18 T 28-03-2018 IPR025416 YqzM-like protein A21D_RS09445 f41545a6debae75b1a6ea1a178f64e25 73 Pfam PF12796 Ankyrin repeats (3 copies) 5 64 4.1E-9 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain A21D_RS09445 f41545a6debae75b1a6ea1a178f64e25 73 Gene3D G3DSA:1.25.40.20 1 73 5.4E-19 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain A21D_RS09445 f41545a6debae75b1a6ea1a178f64e25 73 SUPERFAMILY SSF48403 5 66 3.89E-15 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 Gene3D G3DSA:3.40.190.10 32 140 4.6E-10 T 28-03-2018 A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 Gene3D G3DSA:3.40.190.10 142 290 1.9E-35 T 28-03-2018 A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 293 4.7E-68 T 28-03-2018 A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 SMART SM00062 52 284 0.0089 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 SUPERFAMILY SSF53850 39 301 5.94E-48 T 28-03-2018 A21D_RS01175 7db97276776e80f7eb3aa38ec9341c21 310 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 8 266 1.6E-67 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 A21D_RS08975 6c748802cac313ff5894677d4c678988 333 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 3 328 1.5E-111 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A21D_RS08975 6c748802cac313ff5894677d4c678988 333 SUPERFAMILY SSF53850 42 329 8.09E-79 T 28-03-2018 A21D_RS08975 6c748802cac313ff5894677d4c678988 333 Gene3D G3DSA:3.40.190.10 158 330 4.0E-38 T 28-03-2018 A21D_RS08975 6c748802cac313ff5894677d4c678988 333 Gene3D G3DSA:3.40.190.10 40 157 1.1E-21 T 28-03-2018 A21D_RS08975 6c748802cac313ff5894677d4c678988 333 Pfam PF16868 NMT1-like family 49 328 9.3E-89 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 Pfam PF12844 Helix-turn-helix domain 8 70 1.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 Pfam PF07883 Cupin domain 110 178 4.0E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 SUPERFAMILY SSF51182 58 181 5.49E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 SMART SM00530 10 65 7.9E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 Gene3D G3DSA:1.10.260.40 1 97 2.4E-18 T 28-03-2018 A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 Gene3D G3DSA:2.60.120.10 98 181 1.2E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS12690 af59e8550ab85ae6de29e7009c40a43f 182 SUPERFAMILY SSF47413 4 72 1.15E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS16825 abd9f94fbd744ca3dbe27a09bee961ac 224 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 221 6.5E-70 T 28-03-2018 IPR003744 Queuosine precursor transporter A21D_RS16825 abd9f94fbd744ca3dbe27a09bee961ac 224 Pfam PF02592 Putative vitamin uptake transporter 57 217 4.8E-52 T 28-03-2018 IPR003744 Queuosine precursor transporter A21D_RS15530 6aac79de16baf8614424e42ee4e337c1 48 SUPERFAMILY SSF100985 1 44 4.32E-16 T 28-03-2018 IPR015064 Sporulation inhibitor A A21D_RS15530 6aac79de16baf8614424e42ee4e337c1 48 Gene3D G3DSA:1.10.287.1100 4 36 9.9E-16 T 28-03-2018 IPR015064 Sporulation inhibitor A A21D_RS15530 6aac79de16baf8614424e42ee4e337c1 48 Pfam PF08970 Sporulation inhibitor A 1 44 2.4E-20 T 28-03-2018 IPR015064 Sporulation inhibitor A A21D_RS06915 cf066e9ee8a553e859dcaae5826313d2 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 83 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A21D_RS06915 cf066e9ee8a553e859dcaae5826313d2 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 45.462 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A21D_RS06915 cf066e9ee8a553e859dcaae5826313d2 152 Pfam PF14437 MafB19-like deaminase 4 142 9.8E-46 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A21D_RS06915 cf066e9ee8a553e859dcaae5826313d2 152 SUPERFAMILY SSF53927 1 146 4.52E-54 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS06915 cf066e9ee8a553e859dcaae5826313d2 152 Gene3D G3DSA:3.40.140.10 1 152 7.9E-52 T 28-03-2018 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SUPERFAMILY SSF158472 58 106 9.15E-7 T 28-03-2018 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Pfam PF00989 PAS fold 116 223 4.8E-9 T 28-03-2018 IPR013767 PAS fold GO:0006355 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 3.9E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 3.9E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 3.9E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 3.9E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SUPERFAMILY SSF55874 288 454 2.49E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SMART SM00091 116 182 1.5E-7 T 28-03-2018 IPR000014 PAS domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 298 6.3E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 230 9.2E-13 T 28-03-2018 IPR000014 PAS domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 455 1.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SMART SM00304 57 109 1.2E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Gene3D G3DSA:3.30.565.10 294 456 7.3E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SUPERFAMILY SSF55785 121 228 1.19E-13 T 28-03-2018 IPR000014 PAS domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SUPERFAMILY SSF47384 219 299 3.73E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SMART SM00388 232 299 7.8E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Gene3D G3DSA:1.10.287.130 238 293 1.8E-18 T 28-03-2018 A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 SMART SM00387 344 456 9.4E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS14600 d2e2768d2d7f971d4f6be81e6737bcb5 461 Gene3D G3DSA:3.30.450.20 114 237 1.4E-20 T 28-03-2018 A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 SUPERFAMILY SSF53613 2 285 3.27E-64 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 Gene3D G3DSA:3.40.1190.20 44 304 5.2E-38 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.1E-101 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 Gene3D G3DSA:2.20.150.10 10 43 2.3E-10 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 4.4E-104 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 Pfam PF00294 pfkB family carbohydrate kinase 9 286 7.1E-51 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS08550 f7147ccc62c7337b42576750485b0af0 305 PIRSF PIRSF000535 1 303 9.9E-74 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 PIRSF PIRSF001365 1 291 1.6E-93 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 4.0E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 4.0E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 4.0E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 4.0E-32 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 SUPERFAMILY SSF51569 3 290 1.15E-97 T 28-03-2018 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 2.0E-102 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 Gene3D G3DSA:3.20.20.70 1 291 1.8E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 SMART SM01130 2 290 1.6E-129 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 62.008 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS17660 fbf41da1de670329706fb63b7e52ec24 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 288 4.6E-107 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 Gene3D G3DSA:3.90.1150.10 248 279 2.4E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 364 1.7E-132 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 Gene3D G3DSA:3.40.640.10 4 247 1.3E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 SUPERFAMILY SSF53383 13 364 1.6E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 Gene3D G3DSA:3.90.1150.10 280 366 4.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11170 fef51bc972d7f41719e2e529378aa5d4 366 PIRSF PIRSF001434 1 366 1.5E-124 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 69 205 4.3E-19 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 SUPERFAMILY SSF53901 220 360 1.1E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 SUPERFAMILY SSF53901 2 209 1.51E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 Gene3D G3DSA:3.40.47.10 218 361 1.4E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 235 358 2.7E-15 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 PIRSF PIRSF000451 1 361 1.3E-121 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 A21D_RS16815 c7fecd22c3b8ab8c69d4f84c1dd4757d 361 Gene3D G3DSA:3.40.47.10 2 208 7.4E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 134 282 3.8E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 SUPERFAMILY SSF48150 115 300 6.98E-42 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 SMART SM00478 136 301 6.8E-25 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 Gene3D G3DSA:1.10.1670.10 251 301 4.9E-11 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 Gene3D G3DSA:3.30.310.20 8 125 3.3E-10 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A21D_RS05065 9fe3edde5c301e57d98aa241809f5f23 302 Gene3D G3DSA:1.10.340.30 126 248 2.3E-23 T 28-03-2018 A21D_RS00800 0d1ff685d4d71b05b4e8d6c505d6f5f6 402 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 193 400 2.9E-62 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A21D_RS00800 0d1ff685d4d71b05b4e8d6c505d6f5f6 402 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 5.2E-22 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A21D_RS03015 cefcdbf3bdefa858ec89e96d7f725664 262 SUPERFAMILY SSF89550 1 260 2.88E-43 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS03015 cefcdbf3bdefa858ec89e96d7f725664 262 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 235 1.2E-63 T 28-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 A21D_RS03015 cefcdbf3bdefa858ec89e96d7f725664 262 SMART SM00481 2 84 3.0E-4 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS03015 cefcdbf3bdefa858ec89e96d7f725664 262 Pfam PF02811 PHP domain 3 191 2.8E-14 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS03015 cefcdbf3bdefa858ec89e96d7f725664 262 Gene3D G3DSA:3.20.20.140 1 259 1.1E-39 T 28-03-2018 A21D_RS11025 e4adc74622b594997dfdd82c6dcc84fe 96 SUPERFAMILY SSF141000 3 94 6.93E-33 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A21D_RS11025 e4adc74622b594997dfdd82c6dcc84fe 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.2E-23 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A21D_RS11025 e4adc74622b594997dfdd82c6dcc84fe 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.242 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A21D_RS11025 e4adc74622b594997dfdd82c6dcc84fe 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 2.6E-35 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 4.9E-32 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 4.9E-32 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 4.9E-32 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.9E-32 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 4.9E-32 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 1.5E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 6.5E-172 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 Gene3D G3DSA:3.50.50.60 2 172 1.3E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 3.5E-38 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PIRSF PIRSF000350 1 471 1.1E-85 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 Gene3D G3DSA:3.40.50.720 173 341 1.8E-30 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 SUPERFAMILY SSF55424 350 472 2.23E-42 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 Gene3D G3DSA:3.30.390.30 342 471 1.3E-41 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 1.5E-65 T 28-03-2018 A21D_RS16190 3a95a0cee9ee5ad067ee9260ea2394e4 473 SUPERFAMILY SSF51905 3 344 5.18E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 Pfam PF00232 Glycosyl hydrolase family 1 6 485 1.4E-134 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 425 442 2.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 391 2.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 332 2.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 415 2.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 450 462 2.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 SUPERFAMILY SSF51445 74 486 1.43E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 SUPERFAMILY SSF51445 7 45 1.43E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 383 391 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A21D_RS10730 4bcdc0f802be981029a478890c7b3aa2 490 Gene3D G3DSA:3.20.20.80 1 489 2.0E-150 T 28-03-2018 A21D_RS16270 95d4394979b0d401ebb3fbfc68b06f8f 327 SUPERFAMILY SSF56281 8 309 1.34E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS16270 95d4394979b0d401ebb3fbfc68b06f8f 327 SMART SM00849 21 236 4.7E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS16270 95d4394979b0d401ebb3fbfc68b06f8f 327 Pfam PF00753 Metallo-beta-lactamase superfamily 25 236 2.9E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS16270 95d4394979b0d401ebb3fbfc68b06f8f 327 Gene3D G3DSA:3.60.15.10 1 258 1.8E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 SUPERFAMILY SSF53187 143 456 1.26E-100 T 28-03-2018 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 Gene3D G3DSA:3.40.220.10 21 121 2.9E-4 T 28-03-2018 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 Gene3D G3DSA:3.40.630.10 132 465 1.2E-115 T 28-03-2018 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 306 313 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 147 451 8.4E-104 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 PRINTS PR00481 Cytosol aminopeptidase signature 302 322 3.3E-44 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 PRINTS PR00481 Cytosol aminopeptidase signature 280 301 3.3E-44 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 PRINTS PR00481 Cytosol aminopeptidase signature 221 238 3.3E-44 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 PRINTS PR00481 Cytosol aminopeptidase signature 330 345 3.3E-44 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A21D_RS01650 7b701035e09a12544fafa3cc2aff127e 471 PRINTS PR00481 Cytosol aminopeptidase signature 243 264 3.3E-44 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A21D_RS18810 30ddeec7b6a0ae2d05b62ce0a8011830 454 Pfam PF02386 Cation transport protein 43 443 2.9E-60 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 SUPERFAMILY SSF55781 70 244 5.56E-40 T 28-03-2018 IPR029016 GAF domain-like A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 Gene3D G3DSA:1.10.10.10 1 90 1.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 Gene3D G3DSA:3.30.450.40 91 248 1.3E-41 T 28-03-2018 IPR029016 GAF domain-like A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 SUPERFAMILY SSF46785 3 78 1.97E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 Pfam PF09339 IclR helix-turn-helix domain 4 53 5.1E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 SMART SM00346 2 94 1.1E-29 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A21D_RS11500 6212e89eb8736339a47fe51df39973d2 249 Pfam PF01614 Bacterial transcriptional regulator 122 240 6.0E-22 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Pfam PF14698 Argininosuccinate lyase C-terminal 363 428 1.9E-21 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 431 9.3E-177 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Gene3D G3DSA:1.10.275.10 2 106 9.7E-36 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 310 329 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 1.0E-60 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Gene3D G3DSA:1.20.200.10 107 374 2.2E-91 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 SUPERFAMILY SSF48557 3 432 6.91E-135 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Gene3D G3DSA:1.10.40.30 375 432 1.3E-22 T 28-03-2018 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Pfam PF00206 Lyase 6 300 2.4E-80 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 438 39.251 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS10720 ec114e041cdc290b2da681ac668c8ca1 440 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family A21D_RS15730 2f57fe41d40e09f65a5356c9d0b052ab 47 Pfam PF14006 YqzL-like protein 3 40 1.1E-15 T 28-03-2018 IPR025617 YqzL-like protein A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Gene3D G3DSA:3.30.450.40 217 384 4.5E-7 T 28-03-2018 IPR029016 GAF domain-like A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Gene3D G3DSA:3.30.565.10 415 580 3.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS01255 222cc2648492e25d346fa03be6190149 581 SUPERFAMILY SSF55874 430 573 1.57E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Pfam PF06580 Histidine kinase 375 453 7.7E-26 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A21D_RS01255 222cc2648492e25d346fa03be6190149 581 SMART SM00387 468 576 4.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Pfam PF13492 GAF domain 237 360 1.1E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 A21D_RS01255 222cc2648492e25d346fa03be6190149 581 SUPERFAMILY SSF55781 241 369 6.62E-8 T 28-03-2018 IPR029016 GAF domain-like A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Pfam PF07694 5TMR of 5TMR-LYT 26 204 6.5E-49 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A21D_RS01255 222cc2648492e25d346fa03be6190149 581 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 575 4.1E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 476 495 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Gene3D G3DSA:3.40.50.1220 212 388 1.9E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 196 1.7E-29 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 592 1.5E-39 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 SUPERFAMILY SSF52518 3 210 4.42E-29 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 6 635 3.4E-267 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 2 638 56.645 T 28-03-2018 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Gene3D G3DSA:3.40.50.970 2 211 1.2E-40 T 28-03-2018 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Gene3D G3DSA:3.40.50.970 397 603 5.3E-41 T 28-03-2018 A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 SUPERFAMILY SSF52467 186 365 6.34E-37 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 SUPERFAMILY SSF52518 417 620 1.64E-53 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS01965 1387403f54a9a267ac7524e2ef17b1a2 638 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 354 8.1E-32 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 Gene3D G3DSA:3.40.50.2020 7 156 2.5E-69 T 28-03-2018 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 50.914 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 Gene3D G3DSA:3.40.50.2020 157 310 1.9E-41 T 28-03-2018 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 2.3E-128 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 7.0E-54 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 SMART SM01400 10 126 9.4E-84 T 28-03-2018 A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 SUPERFAMILY SSF53271 75 308 1.52E-66 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS06755 87eaad3c76cb52550bc03c8f6ca16e3d 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 7.7E-26 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 175 180 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 SUPERFAMILY SSF102712 148 192 9.81E-6 T 28-03-2018 A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 226 5.5E-82 T 28-03-2018 IPR001405 RadC protein A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 SUPERFAMILY SSF47781 25 91 1.87E-5 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 Gene3D G3DSA:1.10.150.20 28 89 8.7E-5 T 28-03-2018 A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 Pfam PF04002 RadC-like JAB domain 105 224 5.8E-48 T 28-03-2018 IPR025657 RadC-like JAB domain A21D_RS15175 e6bfdc5ae2a41b599e0630ebf54f37b7 226 Gene3D G3DSA:3.40.140.10 101 226 1.4E-52 T 28-03-2018 A21D_RS06265 2dd0378b0ec73c604fb845d335a18c42 111 Gene3D G3DSA:2.30.30.30 7 105 1.3E-11 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A21D_RS06265 2dd0378b0ec73c604fb845d335a18c42 111 SUPERFAMILY SSF50104 9 80 2.71E-13 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.8E-12 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 3.8E-12 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.8E-12 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 3.8E-12 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 5.4E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 5.4E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 5.4E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 5.4E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 5.4E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 Gene3D G3DSA:3.50.50.60 2 169 8.1E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 Gene3D G3DSA:3.40.50.720 170 321 3.8E-19 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 SUPERFAMILY SSF51905 2 264 8.21E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 289 3.8E-100 T 28-03-2018 A21D_RS16495 ff6d2c5fb3f608da3f12f0a807ca545f 321 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 318 2.1E-140 T 28-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Pfam PF00072 Response regulator receiver domain 709 820 1.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Gene3D G3DSA:3.40.50.2300 698 897 7.0E-42 T 28-03-2018 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Pfam PF00512 His Kinase A (phospho-acceptor) domain 434 501 3.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SUPERFAMILY SSF55874 892 1030 7.07E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SMART SM00387 926 1034 4.2E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SMART SM00387 547 658 6.2E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SUPERFAMILY SSF55874 490 656 4.85E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Gene3D G3DSA:1.10.287.130 423 496 9.2E-15 T 28-03-2018 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Gene3D G3DSA:3.30.565.10 505 660 3.9E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Pfam PF06580 Histidine kinase 837 916 3.5E-23 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 611 4.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 PRINTS PR00344 Bacterial sensor protein C-terminal signature 583 597 4.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 636 4.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 PRINTS PR00344 Bacterial sensor protein C-terminal signature 642 655 4.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Gene3D G3DSA:3.30.565.10 898 1035 4.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 548 657 5.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 934 1033 4.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SMART SM00448 707 820 1.8E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SMART SM00388 433 501 7.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SUPERFAMILY SSF47384 421 501 8.63E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 Gene3D G3DSA:2.60.120.260 51 220 1.7E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SUPERFAMILY SSF49785 57 197 7.44E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like A21D_RS03855 5e6652c1501d08a294420213c950bd3e 1037 SUPERFAMILY SSF52172 706 850 6.4E-39 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 Pfam PF02040 Arsenical pump membrane protein 7 428 1.2E-217 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 368 393 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 148 172 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 221 246 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 181 204 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 327 349 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 282 306 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 PRINTS PR00758 Arsenical pump membrane protein signature 401 425 2.0E-105 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS08360 cb92581465bf752b89b5223a488f187b 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 7 430 1.6E-221 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 SUPERFAMILY SSF90123 6 307 4.84E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 Gene3D G3DSA:3.40.50.300 324 579 7.0E-78 T 28-03-2018 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 Pfam PF00664 ABC transporter transmembrane region 21 242 1.6E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 Gene3D G3DSA:1.20.1560.10 4 307 6.8E-28 T 28-03-2018 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 SMART SM00382 363 549 3.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 Pfam PF00005 ABC transporter 354 503 3.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06050 32fbb954f6e29cfeb4b3495d2ff95a3b 588 SUPERFAMILY SSF52540 331 571 2.95E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04280 becdc74310c30dfca137bd16ef5aee22 426 Pfam PF00534 Glycosyl transferases group 1 238 404 1.9E-21 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS04280 becdc74310c30dfca137bd16ef5aee22 426 SUPERFAMILY SSF53756 17 61 2.06E-47 T 28-03-2018 A21D_RS04280 becdc74310c30dfca137bd16ef5aee22 426 SUPERFAMILY SSF53756 135 425 2.06E-47 T 28-03-2018 A21D_RS04280 becdc74310c30dfca137bd16ef5aee22 426 Gene3D G3DSA:3.40.50.2000 227 410 2.1E-31 T 28-03-2018 A21D_RS13650 e73f07ccdc704b76a12f58fea9732a18 75 SUPERFAMILY SSF47413 6 70 2.09E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS13650 e73f07ccdc704b76a12f58fea9732a18 75 Gene3D G3DSA:1.10.260.40 1 75 3.1E-9 T 28-03-2018 A21D_RS13650 e73f07ccdc704b76a12f58fea9732a18 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 70 1.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 Gene3D G3DSA:3.30.70.141 98 244 0.0014 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 303 318 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 271 286 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 Pfam PF01022 Bacterial regulatory protein, arsR family 276 321 2.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 SMART SM00418 267 343 5.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 Gene3D G3DSA:1.10.10.10 267 335 3.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07820 97f8a2f1ffefc401e774532a02f1d825 347 SUPERFAMILY SSF46785 271 345 2.73E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:3.30.70.370 706 880 4.6E-55 T 28-03-2018 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:3.30.70.370 608 697 8.7E-17 T 28-03-2018 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 262 1.5E-32 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:3.40.50.1010 3 180 2.3E-71 T 28-03-2018 IPR029060 PIN domain-like A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:1.10.150.20 181 244 1.1E-30 T 28-03-2018 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Pfam PF00476 DNA polymerase family A 502 877 1.8E-161 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SUPERFAMILY SSF47807 171 286 8.97E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 827 840 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 706 731 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 682 695 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 606 628 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 675 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 743 754 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 776 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 797 813 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 644 5.6E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 TIGRFAM TIGR00593 pola: DNA polymerase I 5 880 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:3.30.420.10 318 494 6.3E-23 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Gene3D G3DSA:1.20.1060.10 495 607 1.5E-36 T 28-03-2018 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SUPERFAMILY SSF56672 474 880 3.67E-159 T 28-03-2018 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SUPERFAMILY SSF53098 305 472 3.03E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 ProSitePatterns PS00447 DNA polymerase family A signature. 706 725 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SMART SM00474 311 470 5.4E-4 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SUPERFAMILY SSF88723 2 168 2.23E-58 T 28-03-2018 IPR029060 PIN domain-like A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SMART SM00279 173 208 5.1E-18 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SMART SM00475 3 262 9.4E-144 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 169 3.2E-56 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A21D_RS14605 cbeb47ee0b8f88be789928c04ed68eb8 880 SMART SM00482 637 844 5.0E-116 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS06840 c7c05037c17b89cdbcfca7c13eba2206 115 Hamap MF_01159 Initiation-control protein YabA. 1 113 23.931 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A21D_RS06840 c7c05037c17b89cdbcfca7c13eba2206 115 Gene3D G3DSA:1.20.5.340 1 72 1.1E-5 T 28-03-2018 A21D_RS06840 c7c05037c17b89cdbcfca7c13eba2206 115 Pfam PF06156 Initiation control protein YabA 3 109 1.0E-35 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A21D_RS06840 c7c05037c17b89cdbcfca7c13eba2206 115 PIRSF PIRSF021439 1 114 2.7E-40 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A21D_RS03265 7fdb5e27ddf4cc67e745461404818da8 115 SUPERFAMILY SSF52833 4 108 2.09E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS03265 7fdb5e27ddf4cc67e745461404818da8 115 Gene3D G3DSA:3.40.30.10 1 112 3.7E-13 T 28-03-2018 A21D_RS03265 7fdb5e27ddf4cc67e745461404818da8 115 Pfam PF00085 Thioredoxin 16 88 1.4E-6 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS13470 db375861834f7c03911ee7c7caba5d87 131 Gene3D G3DSA:3.40.30.10 1 131 1.1E-39 T 28-03-2018 A21D_RS13470 db375861834f7c03911ee7c7caba5d87 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 5.4E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR A21D_RS13470 db375861834f7c03911ee7c7caba5d87 131 Pfam PF03960 ArsC family 5 113 7.0E-23 T 28-03-2018 IPR006660 Arsenate reductase-like A21D_RS13470 db375861834f7c03911ee7c7caba5d87 131 SUPERFAMILY SSF52833 1 129 1.42E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS13470 db375861834f7c03911ee7c7caba5d87 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 38.14 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 Gene3D G3DSA:1.20.120.640 306 407 8.8E-22 T 28-03-2018 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 465 7.6E-187 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 SUPERFAMILY SSF52374 3 314 9.65E-105 T 28-03-2018 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 Pfam PF09190 DALR domain 353 414 2.1E-16 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 SMART SM00840 353 417 7.7E-18 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 Gene3D G3DSA:3.40.50.620 1 305 1.3E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 466 39.709 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 4.2E-135 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A21D_RS06480 34fb292f4ccc95d9ed5f6d8ea616bfa1 466 SUPERFAMILY SSF47323 341 465 4.91E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS08220 27a89b69874d4282ba278a5a320143dd 140 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 1 139 1.2E-35 T 28-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS08220 27a89b69874d4282ba278a5a320143dd 140 Pfam PF06754 Phosphonate metabolism protein PhnG 2 138 1.2E-34 T 28-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS10310 83748d89820a104a8517fe89643d40a9 176 Pfam PF03838 Recombination protein U 9 168 2.9E-46 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS10310 83748d89820a104a8517fe89643d40a9 176 PIRSF PIRSF037785 1 176 4.2E-58 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS10310 83748d89820a104a8517fe89643d40a9 176 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 176 49.74 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS10310 83748d89820a104a8517fe89643d40a9 176 SUPERFAMILY SSF52980 11 171 1.98E-47 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS10310 83748d89820a104a8517fe89643d40a9 176 Gene3D G3DSA:3.40.1350.10 10 170 7.5E-48 T 28-03-2018 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 Pfam PF00813 FliP family 25 217 1.9E-82 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 1.1E-91 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 1.5E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS17870 542c4a515206e3bab9b7f97e1916a7f0 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 8.4E-25 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A21D_RS13620 78c0ee5115d2c98bb3df48919a32d205 331 Gene3D G3DSA:1.10.443.10 133 307 1.1E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS13620 78c0ee5115d2c98bb3df48919a32d205 331 Gene3D G3DSA:1.10.150.130 4 131 2.1E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS13620 78c0ee5115d2c98bb3df48919a32d205 331 SUPERFAMILY SSF56349 11 303 1.59E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS13620 78c0ee5115d2c98bb3df48919a32d205 331 Pfam PF00589 Phage integrase family 134 302 2.3E-36 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS13620 78c0ee5115d2c98bb3df48919a32d205 331 Pfam PF13102 Phage integrase SAM-like domain 24 120 1.6E-10 T 28-03-2018 IPR025269 Phage integrase SAM-like domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF08279 HTH domain 2 56 2.2E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 SUPERFAMILY SSF52794 407 487 1.67E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 SUPERFAMILY SSF63520 299 400 2.88E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 SUPERFAMILY SSF63520 183 279 8.89E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF05043 Mga helix-turn-helix domain 87 163 4.1E-15 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 SUPERFAMILY SSF55804 496 637 3.4E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 499 636 1.0E-26 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF00874 PRD domain 195 279 8.2E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF00874 PRD domain 307 396 5.9E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:1.10.10.10 1 60 5.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:1.10.10.10 83 151 5.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 409 486 7.8E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:3.40.930.10 495 638 5.4E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 SUPERFAMILY SSF46785 86 130 5.75E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:1.10.1790.10 176 281 1.2E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:1.10.1790.10 288 400 2.0E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12425 889e2ea4b0ed83a0394cda7cd5c45063 639 Gene3D G3DSA:3.40.50.2300 404 494 5.1E-20 T 28-03-2018 A21D_RS01900 b0fdfb04c1e1dadb93e48602cd35eead 220 Gene3D G3DSA:3.40.225.10 2 216 2.0E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01900 b0fdfb04c1e1dadb93e48602cd35eead 220 SMART SM01007 9 186 1.2E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01900 b0fdfb04c1e1dadb93e48602cd35eead 220 SUPERFAMILY SSF53639 5 215 6.67E-65 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01900 b0fdfb04c1e1dadb93e48602cd35eead 220 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 186 1.4E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 1.5E-22 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 SUPERFAMILY SSF54680 331 433 1.26E-26 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 PIRSF PIRSF000478 1 433 5.8E-169 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 8.0E-180 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Gene3D G3DSA:3.40.1030.10 68 337 1.4E-92 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Gene3D G3DSA:3.90.1170.30 338 423 1.2E-25 T 28-03-2018 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.2E-48 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 346 418 6.2E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 Gene3D G3DSA:1.20.970.10 1 66 9.2E-27 T 28-03-2018 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 SUPERFAMILY SSF47648 1 69 9.55E-23 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 SUPERFAMILY SSF52418 71 329 2.09E-92 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS16330 3fdcf57cf37b4432a847b561492984b0 435 SMART SM00941 345 418 4.9E-30 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS11760 5c21e0dd609ab85dcbd0adf91fae6b69 183 Gene3D G3DSA:1.20.1200.10 12 182 6.7E-58 T 28-03-2018 A21D_RS11760 5c21e0dd609ab85dcbd0adf91fae6b69 183 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 174 2.6E-53 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A21D_RS11760 5c21e0dd609ab85dcbd0adf91fae6b69 183 Pfam PF01923 Cobalamin adenosyltransferase 3 169 1.4E-59 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A21D_RS11760 5c21e0dd609ab85dcbd0adf91fae6b69 183 SUPERFAMILY SSF89028 1 178 4.32E-59 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A21D_RS11760 5c21e0dd609ab85dcbd0adf91fae6b69 183 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 173 9.0E-57 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A21D_RS00235 f6f2e724c38caca8873d2eb8c9ceda22 435 SUPERFAMILY SSF101960 12 434 1.15E-120 T 28-03-2018 A21D_RS00235 f6f2e724c38caca8873d2eb8c9ceda22 435 Pfam PF01458 Uncharacterized protein family (UPF0051) 185 409 6.9E-62 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A21D_RS00235 f6f2e724c38caca8873d2eb8c9ceda22 435 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 426 1.3E-77 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A21D_RS01165 c2d8654496d1b57c66faa4c4001e8061 266 SUPERFAMILY SSF161098 71 258 1.31E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01165 c2d8654496d1b57c66faa4c4001e8061 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 264 4.7E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01165 c2d8654496d1b57c66faa4c4001e8061 266 Gene3D G3DSA:1.10.3720.10 20 266 9.3E-29 T 28-03-2018 A21D_RS01165 c2d8654496d1b57c66faa4c4001e8061 266 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 20 265 8.3E-90 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A21D_RS15045 190d33888340e79cce8e248384777001 254 SUPERFAMILY SSF55666 151 237 4.19E-22 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS15045 190d33888340e79cce8e248384777001 254 Hamap MF_00564 Ribonuclease PH [rph]. 1 238 46.325 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A21D_RS15045 190d33888340e79cce8e248384777001 254 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 2.0E-113 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A21D_RS15045 190d33888340e79cce8e248384777001 254 Pfam PF03725 3' exoribonuclease family, domain 2 158 225 3.2E-9 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS15045 190d33888340e79cce8e248384777001 254 Gene3D G3DSA:3.30.230.70 1 241 3.0E-53 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS15045 190d33888340e79cce8e248384777001 254 Pfam PF01138 3' exoribonuclease family, domain 1 11 139 1.1E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A21D_RS15045 190d33888340e79cce8e248384777001 254 SUPERFAMILY SSF54211 1 182 2.38E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS15045 190d33888340e79cce8e248384777001 254 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 PIRSF PIRSF006004 2 355 1.1E-131 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 Pfam PF04055 Radical SAM superfamily 106 278 2.0E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 Gene3D G3DSA:3.20.20.70 12 350 4.2E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 Pfam PF13394 4Fe-4S single cluster domain 111 209 1.5E-7 T 28-03-2018 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 3 350 70.539 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 SUPERFAMILY SSF102114 100 314 5.62E-15 T 28-03-2018 A21D_RS08770 69cbd8f26560e4123154e62444dcb8cf 355 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 353 1.8E-130 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS08250 94fbc0b0d75bbea699b8fc741982864d 240 Gene3D G3DSA:3.40.50.300 1 240 1.2E-52 T 28-03-2018 A21D_RS08250 94fbc0b0d75bbea699b8fc741982864d 240 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 3 225 3.0E-80 T 28-03-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS08250 94fbc0b0d75bbea699b8fc741982864d 240 SUPERFAMILY SSF52540 3 225 7.83E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08250 94fbc0b0d75bbea699b8fc741982864d 240 Pfam PF00005 ABC transporter 26 180 2.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08250 94fbc0b0d75bbea699b8fc741982864d 240 SMART SM00382 34 227 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01905 57022604cdac050b3b619b76a8501e04 215 SUPERFAMILY SSF53639 4 195 1.22E-38 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01905 57022604cdac050b3b619b76a8501e04 215 SMART SM01007 8 191 4.1E-27 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01905 57022604cdac050b3b619b76a8501e04 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 189 1.4E-31 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS01905 57022604cdac050b3b619b76a8501e04 215 Gene3D G3DSA:3.40.225.10 3 209 4.3E-42 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS08900 1f2484b4f712911deed9394c4773c679 125 SUPERFAMILY SSF50729 6 124 1.35E-46 T 28-03-2018 IPR011993 PH domain-like A21D_RS08900 1f2484b4f712911deed9394c4773c679 125 Gene3D G3DSA:2.30.29.50 13 102 2.0E-39 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain A21D_RS08900 1f2484b4f712911deed9394c4773c679 125 Pfam PF08000 Bacterial PH domain 2 123 4.7E-52 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain A21D_RS09800 e31759701a8f184e4dd70691c8a58221 198 Gene3D G3DSA:1.20.120.80 13 198 1.6E-47 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09800 e31759701a8f184e4dd70691c8a58221 198 Pfam PF00510 Cytochrome c oxidase subunit III 21 196 3.4E-17 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09800 e31759701a8f184e4dd70691c8a58221 198 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 10 198 1.3E-76 T 28-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 A21D_RS09800 e31759701a8f184e4dd70691c8a58221 198 SUPERFAMILY SSF81452 17 196 2.88E-50 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS17900 4dc62dcb9a6b5f3bb0870aba7423507c 73 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.2E-26 T 28-03-2018 IPR009384 Flagellar A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 5.1E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 5.1E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 5.1E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 5.1E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 SUPERFAMILY SSF46911 4 75 2.62E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 Gene3D G3DSA:4.10.640.10 1 76 7.9E-36 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 8 75 1.1E-37 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 76 23.636 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 76 4.0E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07335 8b00a25b607a51a864c8625824190e89 76 Pfam PF01084 Ribosomal protein S18 21 71 2.4E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14140 f3e146aae4045f0d36794d0065201fcd 329 Gene3D G3DSA:3.40.190.10 138 329 1.2E-27 T 28-03-2018 A21D_RS14140 f3e146aae4045f0d36794d0065201fcd 329 Gene3D G3DSA:3.40.190.10 24 129 1.9E-10 T 28-03-2018 A21D_RS14140 f3e146aae4045f0d36794d0065201fcd 329 SUPERFAMILY SSF53850 34 254 5.64E-32 T 28-03-2018 A21D_RS14140 f3e146aae4045f0d36794d0065201fcd 329 Pfam PF09084 NMT1/THI5 like 41 253 3.9E-19 T 28-03-2018 IPR015168 SsuA/THI5-like A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 SMART SM01383 42 118 2.1E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 SUPERFAMILY SSF50104 126 272 4.15E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 2.8E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 PIRSF PIRSF002158 3 276 8.9E-98 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Gene3D G3DSA:2.30.30.30 119 195 1.1E-33 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Gene3D G3DSA:2.40.50.140 1 114 3.8E-49 T 28-03-2018 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 SUPERFAMILY SSF50249 2 125 7.88E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.078 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.0E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 SMART SM01382 124 253 5.2E-91 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 3.8E-138 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A21D_RS06360 c9196394b12ec9016b644ed9dfbbe902 276 Gene3D G3DSA:4.10.950.10 197 275 4.6E-35 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 SMART SM00357 2 65 1.8E-33 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 Gene3D G3DSA:2.40.50.140 1 65 9.7E-29 T 28-03-2018 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 28-03-2018 IPR019844 Cold-shock conserved site A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 SUPERFAMILY SSF50249 1 64 1.32E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 PRINTS PR00050 Cold shock protein signature 23 32 2.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 PRINTS PR00050 Cold shock protein signature 38 56 2.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 PRINTS PR00050 Cold shock protein signature 3 18 2.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 PIRSF PIRSF002599 1 65 1.1E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 A21D_RS02790 066d9a8e59ad741bb52a404ff85b9eeb 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.8E-33 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS08270 9658e87100325589c4987e70e9e2e55b 261 Gene3D G3DSA:1.10.3720.10 4 254 1.3E-26 T 28-03-2018 A21D_RS08270 9658e87100325589c4987e70e9e2e55b 261 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 9 260 1.1E-65 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A21D_RS08270 9658e87100325589c4987e70e9e2e55b 261 SUPERFAMILY SSF161098 65 251 1.57E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08270 9658e87100325589c4987e70e9e2e55b 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 258 5.5E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS06450 6941079b6fb28e451686e29fbb89913a 55 Gene3D G3DSA:1.20.5.1030 1 52 1.4E-21 T 28-03-2018 A21D_RS06450 6941079b6fb28e451686e29fbb89913a 55 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 3 55 1.7E-21 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06450 6941079b6fb28e451686e29fbb89913a 55 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 1 55 8.9E-23 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A21D_RS06450 6941079b6fb28e451686e29fbb89913a 55 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 54 12.588 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06450 6941079b6fb28e451686e29fbb89913a 55 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 4 32 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 52.241 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 PIRSF PIRSF001413 1 398 3.0E-167 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 382 5.2E-48 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 Gene3D G3DSA:3.40.50.1100 202 398 4.6E-42 T 28-03-2018 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 393 9.0E-192 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 Gene3D G3DSA:3.40.50.1100 13 201 1.3E-45 T 28-03-2018 A21D_RS03245 03d55d4accaef8118f0e0ea789cf3bf5 398 SUPERFAMILY SSF53686 7 393 6.81E-146 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS14660 3b4787f82c97b2ee17a765956a5fd0d4 207 SUPERFAMILY SSF53098 35 197 3.19E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14660 3b4787f82c97b2ee17a765956a5fd0d4 207 Pfam PF00665 Integrase core domain 42 157 5.3E-20 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS14660 3b4787f82c97b2ee17a765956a5fd0d4 207 Gene3D G3DSA:3.30.420.10 35 207 4.5E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 Pfam PF00464 Serine hydroxymethyltransferase 4 380 8.0E-181 T 28-03-2018 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 54.517 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 Gene3D G3DSA:3.40.640.10 33 269 9.8E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 PIRSF PIRSF000412 1 413 9.3E-175 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 Gene3D G3DSA:3.90.1150.10 270 410 3.5E-60 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS04595 4dca9f1b03a7e8e58a2b7d7b0a59c2d7 414 SUPERFAMILY SSF53383 2 411 2.58E-183 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS12275 5f1447ab2f9de9dcdc0009b27c582795 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 144 5.0E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS12275 5f1447ab2f9de9dcdc0009b27c582795 149 SUPERFAMILY SSF55804 2 144 1.31E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12275 5f1447ab2f9de9dcdc0009b27c582795 149 Gene3D G3DSA:3.40.930.10 1 146 1.8E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS13185 5664f4ca0acb3a503001b338262d7a4a 249 PIRSF PIRSF031509 6 249 2.5E-32 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 A21D_RS13185 5664f4ca0acb3a503001b338262d7a4a 249 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 135 246 1.3E-24 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A21D_RS10510 7234f0285eb62f7def858fa8b18c2c81 318 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 83 93 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A21D_RS10510 7234f0285eb62f7def858fa8b18c2c81 318 Pfam PF00082 Subtilase family 9 139 6.6E-11 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS10510 7234f0285eb62f7def858fa8b18c2c81 318 SUPERFAMILY SSF52743 5 139 3.01E-14 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS10510 7234f0285eb62f7def858fa8b18c2c81 318 Gene3D G3DSA:3.40.50.200 3 158 4.5E-13 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS18770 8c9ccb31340b7075136fd3bb246d6233 51 Pfam PF13040 Fur-regulated basic protein B 1 37 2.0E-13 T 28-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS A21D_RS17140 ee8837294ec30e09f7c71a73e8e3831c 142 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 132 2.1E-34 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A21D_RS11880 d0bd4eebf6308f19544752cf271761f8 208 SMART SM01207 12 199 7.8E-70 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS11880 d0bd4eebf6308f19544752cf271761f8 208 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 206 1.7E-48 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS11880 d0bd4eebf6308f19544752cf271761f8 208 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 207 18.544 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS11880 d0bd4eebf6308f19544752cf271761f8 208 Pfam PF02660 Glycerol-3-phosphate acyltransferase 14 198 2.7E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS02110 8ac3f31112f58392f7053a2d3998fd89 132 SUPERFAMILY SSF117856 53 128 5.23E-22 T 28-03-2018 A21D_RS02110 8ac3f31112f58392f7053a2d3998fd89 132 Gene3D G3DSA:3.30.1330.80 50 93 6.9E-14 T 28-03-2018 A21D_RS02110 8ac3f31112f58392f7053a2d3998fd89 132 Pfam PF03306 Alpha-acetolactate decarboxylase 52 116 1.4E-21 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A21D_RS17170 1765ac20dc482b349b2a8a6889f7d64c 77 Pfam PF05979 Bacterial protein of unknown function (DUF896) 6 68 2.8E-30 T 28-03-2018 IPR009242 Protein of unknown function DUF896 A21D_RS17170 1765ac20dc482b349b2a8a6889f7d64c 77 Hamap MF_01103 UPF0291 protein . 2 60 16.189 T 28-03-2018 IPR009242 Protein of unknown function DUF896 A21D_RS17170 1765ac20dc482b349b2a8a6889f7d64c 77 Gene3D G3DSA:1.10.287.540 4 56 1.2E-23 T 28-03-2018 A21D_RS17170 1765ac20dc482b349b2a8a6889f7d64c 77 SUPERFAMILY SSF158221 1 42 3.01E-13 T 28-03-2018 A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 Hamap MF_01970 Kynureninase [kynU]. 5 412 38.705 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 SUPERFAMILY SSF53383 12 414 8.85E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 TIGRFAM TIGR01814 kynureninase: kynureninase 13 413 1.7E-120 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 Gene3D G3DSA:3.40.640.10 48 299 1.9E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 Pfam PF00266 Aminotransferase class-V 87 377 3.7E-22 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 Gene3D G3DSA:3.90.1150.10 300 420 8.9E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11470 f75ca92b8ead1afdcee417b3ef996f43 428 PIRSF PIRSF038800 5 420 8.7E-152 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A21D_RS13770 baec4c2293794fe13bf96383d7707d61 286 Pfam PF00892 EamA-like transporter family 146 276 3.3E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS13770 baec4c2293794fe13bf96383d7707d61 286 Pfam PF00892 EamA-like transporter family 6 137 9.2E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS13770 baec4c2293794fe13bf96383d7707d61 286 SUPERFAMILY SSF103481 40 139 3.53E-11 T 28-03-2018 A21D_RS13770 baec4c2293794fe13bf96383d7707d61 286 SUPERFAMILY SSF103481 180 280 5.49E-15 T 28-03-2018 A21D_RS03920 966fcb777d8ff760a9073d0e9ddc0b86 107 Pfam PF03860 Domain of Unknown Function (DUF326) 87 106 4.2E-7 T 28-03-2018 IPR005560 Protein of unknown function DUF326 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SUPERFAMILY SSF81886 571 826 6.28E-79 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Pfam PF02810 SEC-C motif 818 836 3.8E-10 T 28-03-2018 IPR004027 SEC-C motif A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SUPERFAMILY SSF81767 226 348 2.49E-46 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.982 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Pfam PF07517 SecA DEAD-like domain 5 382 7.5E-132 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Gene3D G3DSA:1.10.3060.10 585 662 6.6E-28 T 28-03-2018 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Gene3D G3DSA:3.40.50.300 397 584 2.4E-56 T 28-03-2018 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Pfam PF01043 SecA preprotein cross-linking domain 231 338 5.9E-42 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 ProSitePatterns PS01312 SecA family signature. 480 495 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SUPERFAMILY SSF52540 348 395 6.42E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SUPERFAMILY SSF52540 4 227 6.42E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 496 7.9E-242 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SMART SM00957 5 382 5.9E-288 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Gene3D G3DSA:3.10.450.50 671 836 7.3E-49 T 28-03-2018 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SMART SM00958 227 338 9.1E-67 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Gene3D G3DSA:3.40.50.300 8 270 1.5E-61 T 28-03-2018 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Gene3D G3DSA:3.40.50.300 291 396 8.2E-8 T 28-03-2018 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 SUPERFAMILY SSF52540 397 569 3.15E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 116 126 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 356 373 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 62 86 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 100 114 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 393 406 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 169 189 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 PRINTS PR00906 SecA protein signature 319 341 1.7E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A21D_RS00790 1edcd885c3cc9b085b92b9933b575732 836 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.3E-64 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 SUPERFAMILY SSF143800 1 80 7.06E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.791 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.6E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.6E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.6E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 81 2.4E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS04665 74bb2fcd4dcfc0b4fcdb1bc60570507b 81 Pfam PF01197 Ribosomal protein L31 1 79 1.0E-27 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 Pfam PF01694 Rhomboid family 226 362 1.5E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 Pfam PF13414 TPR repeat 445 484 7.3E-10 T 28-03-2018 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 Gene3D G3DSA:1.25.40.10 480 508 4.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 Gene3D G3DSA:1.25.40.10 434 479 4.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 Gene3D G3DSA:1.20.1540.10 182 363 4.9E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 SMART SM00028 436 469 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 SMART SM00028 470 503 1.5E-7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 SUPERFAMILY SSF144091 182 366 4.84E-47 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS15895 b1a1197d35e3870dd77f1f826d5d987f 519 SUPERFAMILY SSF48452 387 512 4.98E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS19275 11bbd17024af0cfac839aa9503efb604 159 SUPERFAMILY SSF55729 3 116 1.11E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS19275 11bbd17024af0cfac839aa9503efb604 159 Gene3D G3DSA:3.40.630.30 2 158 2.1E-22 T 28-03-2018 A21D_RS19275 11bbd17024af0cfac839aa9503efb604 159 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 2 153 6.6E-56 T 28-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 A21D_RS19275 11bbd17024af0cfac839aa9503efb604 159 Pfam PF00583 Acetyltransferase (GNAT) family 26 115 2.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS19055 206951fbd7e671d665327832a69faeab 471 Pfam PF04740 LXG domain of WXG superfamily 5 193 1.2E-26 T 28-03-2018 IPR006829 LXG domain A21D_RS19055 206951fbd7e671d665327832a69faeab 471 Gene3D G3DSA:1.20.5.1230 4 471 1.1E-5 T 28-03-2018 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 143 3.0E-4 T 28-03-2018 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 Gene3D G3DSA:3.40.1260.10 9 97 2.6E-4 T 28-03-2018 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 28.324 T 28-03-2018 IPR022973 Ribosomal protein L10 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 SUPERFAMILY SSF160369 5 160 1.24E-52 T 28-03-2018 A21D_RS06430 4656670ba12c1c595e24093b8abc9e75 166 Pfam PF00466 Ribosomal protein L10 5 101 2.1E-29 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A21D_RS06075 06b74eadf36e41949798d54c5f0e8748 302 Gene3D G3DSA:3.40.390.10 5 288 3.2E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A21D_RS06075 06b74eadf36e41949798d54c5f0e8748 302 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 96 294 2.7E-51 T 28-03-2018 IPR018728 Domain of unknown function DUF2268 A21D_RS04105 313c73798b66d5744ceb07290604b2f6 161 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 6 153 2.5E-60 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 A21D_RS04105 313c73798b66d5744ceb07290604b2f6 161 Gene3D G3DSA:3.40.35.10 6 161 3.7E-57 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS04105 313c73798b66d5744ceb07290604b2f6 161 SUPERFAMILY SSF52728 6 160 2.49E-52 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS04105 313c73798b66d5744ceb07290604b2f6 161 Pfam PF03830 PTS system sorbose subfamily IIB component 7 152 1.6E-51 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 56 274 7.2E-78 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 Pfam PF01343 Peptidase family S49 127 276 3.2E-54 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 PRINTS PR00127 Clp protease catalytic subunit P signature 100 120 3.7E-5 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 PRINTS PR00127 Clp protease catalytic subunit P signature 240 259 3.7E-5 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 PRINTS PR00127 Clp protease catalytic subunit P signature 134 151 3.7E-5 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 SUPERFAMILY SSF52096 53 174 1.64E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 SUPERFAMILY SSF52096 203 264 1.64E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS03890 710524de3d930a228c2e92102cb56d3f 330 Gene3D G3DSA:3.90.226.10 49 330 2.7E-44 T 28-03-2018 A21D_RS15465 48f59598237583ff84f05d8f65aa70a5 229 Gene3D G3DSA:3.40.50.1580 1 229 7.8E-53 T 28-03-2018 A21D_RS15465 48f59598237583ff84f05d8f65aa70a5 229 SUPERFAMILY SSF53167 1 226 5.24E-68 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS15465 48f59598237583ff84f05d8f65aa70a5 229 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 43.547 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A21D_RS15465 48f59598237583ff84f05d8f65aa70a5 229 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 227 5.1E-87 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A21D_RS15465 48f59598237583ff84f05d8f65aa70a5 229 Pfam PF01048 Phosphorylase superfamily 2 226 1.5E-47 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 Pfam PF12848 ABC transporter 230 311 6.7E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 SMART SM00382 349 514 4.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 SMART SM00382 28 252 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 SUPERFAMILY SSF52540 5 245 2.13E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 Gene3D G3DSA:3.40.50.300 302 514 3.1E-46 T 28-03-2018 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 SUPERFAMILY SSF52540 305 512 2.84E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 Gene3D G3DSA:3.40.50.300 1 301 4.9E-56 T 28-03-2018 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 Pfam PF00005 ABC transporter 341 469 8.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 Pfam PF00005 ABC transporter 19 191 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09780 6114c002c3121cd720ce2d98215eda12 514 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13630 3189d1f4af800339903c578afda9f37f 349 Gene3D G3DSA:1.10.443.10 155 334 4.5E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS13630 3189d1f4af800339903c578afda9f37f 349 Pfam PF13102 Phage integrase SAM-like domain 39 142 4.5E-6 T 28-03-2018 IPR025269 Phage integrase SAM-like domain A21D_RS13630 3189d1f4af800339903c578afda9f37f 349 SUPERFAMILY SSF56349 29 330 2.02E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS13630 3189d1f4af800339903c578afda9f37f 349 Gene3D G3DSA:1.10.150.130 22 154 3.7E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS13630 3189d1f4af800339903c578afda9f37f 349 Pfam PF00589 Phage integrase family 157 325 5.5E-38 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 SUPERFAMILY SSF52540 334 570 2.61E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 SMART SM00382 363 548 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 Pfam PF00664 ABC transporter transmembrane region 34 280 1.9E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 Gene3D G3DSA:1.20.1560.10 3 320 6.8E-20 T 28-03-2018 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 Pfam PF00005 ABC transporter 354 501 2.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 SUPERFAMILY SSF90123 4 299 2.22E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 SUPERFAMILY SSF90123 478 487 2.22E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 Gene3D G3DSA:3.40.50.300 321 572 3.6E-64 T 28-03-2018 A21D_RS01640 aa879ba4370d49e45b936f797bacd239 583 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 3 532 5.2E-163 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 215 2.1E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 SUPERFAMILY SSF46894 142 216 5.1E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 Pfam PF00072 Response regulator receiver domain 4 111 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 SUPERFAMILY SSF52172 1 164 8.68E-40 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 Gene3D G3DSA:1.10.10.10 125 217 7.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 SMART SM00448 2 111 6.4E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 SMART SM00862 143 215 9.9E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07055 30b0df2a9ed8dc9e00c916bd50ddd89c 217 Gene3D G3DSA:3.40.50.2300 1 124 2.9E-35 T 28-03-2018 A21D_RS10290 94bb04ab1b0b02316a513c126e4d2dc5 310 Pfam PF09588 YqaJ-like viral recombinase domain 12 146 4.5E-32 T 28-03-2018 IPR019080 YqaJ viral recombinase A21D_RS10290 94bb04ab1b0b02316a513c126e4d2dc5 310 SUPERFAMILY SSF52980 5 200 1.29E-47 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS10290 94bb04ab1b0b02316a513c126e4d2dc5 310 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 6 157 6.6E-41 T 28-03-2018 IPR017482 Putative phage-type endonuclease A21D_RS10290 94bb04ab1b0b02316a513c126e4d2dc5 310 Gene3D G3DSA:3.90.320.10 6 212 4.6E-50 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 407 534 1.2E-23 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 Gene3D G3DSA:3.50.50.60 3 102 5.4E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 44 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 50 62 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 21 33 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 95 107 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 338 344 7.0E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 Gene3D G3DSA:3.30.9.10 103 202 1.2E-10 T 28-03-2018 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 Gene3D G3DSA:3.30.9.10 203 345 1.7E-37 T 28-03-2018 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 26 43 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 SUPERFAMILY SSF54373 251 344 1.94E-10 T 28-03-2018 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 SUPERFAMILY SSF51905 158 239 5.79E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 SUPERFAMILY SSF51905 11 91 5.79E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00680 2baf82de0cb007e17c29630c50be13d0 556 Pfam PF01266 FAD dependent oxidoreductase 22 351 1.1E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 SUPERFAMILY SSF56176 3 212 3.5E-65 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 Pfam PF01565 FAD binding domain 38 175 4.0E-40 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 SUPERFAMILY SSF55103 218 453 2.62E-64 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 Gene3D G3DSA:3.30.43.10 2 90 2.6E-25 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 451 2.3E-57 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 Gene3D G3DSA:1.10.45.10 413 451 3.6E-13 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A21D_RS02385 bc3e2401b17c8a9cc16df62441d9c236 456 Gene3D G3DSA:3.30.465.10 91 234 1.5E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS06905 0ad17b8564b17674c282a4a75a6c520f 193 Pfam PF00484 Carbonic anhydrase 34 178 2.8E-17 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS06905 0ad17b8564b17674c282a4a75a6c520f 193 SUPERFAMILY SSF53056 4 181 9.94E-41 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS06905 0ad17b8564b17674c282a4a75a6c520f 193 SMART SM00947 26 182 2.9E-37 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS06905 0ad17b8564b17674c282a4a75a6c520f 193 Gene3D G3DSA:3.40.1050.10 2 192 2.0E-32 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS13570 97d55e87189c3710d3d83991a8f9bf20 172 Hamap MF_01444 Putative phosphoesterase . 1 168 39.037 T 28-03-2018 IPR022932 Putative phosphoesterase YjcG A21D_RS13570 97d55e87189c3710d3d83991a8f9bf20 172 SUPERFAMILY SSF55144 1 168 1.15E-32 T 28-03-2018 IPR009097 Cyclic phosphodiesterase A21D_RS13570 97d55e87189c3710d3d83991a8f9bf20 172 Pfam PF13563 2'-5' RNA ligase superfamily 11 153 1.9E-24 T 28-03-2018 A21D_RS13570 97d55e87189c3710d3d83991a8f9bf20 172 Gene3D G3DSA:3.90.1140.10 1 171 3.4E-27 T 28-03-2018 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 Pfam PF01765 Ribosome recycling factor 20 180 2.3E-64 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 SUPERFAMILY SSF55194 4 182 2.75E-70 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 Gene3D G3DSA:1.10.132.20 75 181 5.7E-40 T 28-03-2018 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 Gene3D G3DSA:1.10.132.20 3 74 7.3E-10 T 28-03-2018 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 182 1.2E-72 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A21D_RS17775 8df638ae0b0723681a142e4935c581c9 182 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 182 27.963 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 Gene3D G3DSA:3.40.50.10490 2 223 4.0E-47 T 28-03-2018 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 3 279 5.1E-100 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 279 34.226 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 Pfam PF01380 SIS domain 102 190 2.6E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 SUPERFAMILY SSF53697 2 232 3.11E-64 T 28-03-2018 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 Gene3D G3DSA:1.10.8.10 224 253 3.8E-7 T 28-03-2018 A21D_RS01055 a54db767e2535d8ef6be9986a27d8f78 287 Gene3D G3DSA:1.10.8.10 261 281 0.36 T 28-03-2018 A21D_RS09170 4da5990ba2fa6da6e95743d7a3f8ab1c 236 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 134 233 9.1E-7 T 28-03-2018 IPR018745 Domain of unknown function DUF2294 A21D_RS09170 4da5990ba2fa6da6e95743d7a3f8ab1c 236 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 10 112 1.2E-16 T 28-03-2018 IPR018745 Domain of unknown function DUF2294 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 7.2E-289 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 SUPERFAMILY SSF100920 354 510 3.4E-63 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Gene3D G3DSA:2.60.34.10 360 501 1.3E-67 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 37.396 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Gene3D G3DSA:1.20.1270.10 502 588 2.3E-22 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 SUPERFAMILY SSF53067 1 157 2.72E-58 T 28-03-2018 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 SUPERFAMILY SSF100934 477 576 4.05E-16 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Gene3D G3DSA:3.30.420.40 1 170 2.3E-69 T 28-03-2018 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Pfam PF00012 Hsp70 protein 76 573 5.1E-223 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 358 377 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 335 355 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 439 455 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.9E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 Gene3D G3DSA:3.30.420.40 171 332 5.6E-49 T 28-03-2018 A21D_RS15640 d11d4a69f6f7d2b47e34a0b59e847f74 613 SUPERFAMILY SSF53067 160 352 1.71E-67 T 28-03-2018 A21D_RS07005 dae3282a74768b9968e476e54f34a3c9 72 Gene3D G3DSA:1.20.120.540 1 72 3.7E-11 T 28-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 A21D_RS07005 dae3282a74768b9968e476e54f34a3c9 72 Pfam PF07690 Major Facilitator Superfamily 4 72 1.2E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS07005 dae3282a74768b9968e476e54f34a3c9 72 SUPERFAMILY SSF103473 1 72 8.63E-11 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS13710 4712af9132c3e3da51489c663cd56700 804 Gene3D G3DSA:1.10.287.1060 16 108 1.8E-4 T 28-03-2018 A21D_RS13710 4712af9132c3e3da51489c663cd56700 804 Pfam PF10145 Phage-related minor tail protein 91 280 4.7E-19 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS13710 4712af9132c3e3da51489c663cd56700 804 Gene3D G3DSA:1.10.287.700 595 796 5.5E-6 T 28-03-2018 A21D_RS13710 4712af9132c3e3da51489c663cd56700 804 Gene3D G3DSA:1.10.287.700 428 530 0.044 T 28-03-2018 A21D_RS13710 4712af9132c3e3da51489c663cd56700 804 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 53 398 2.3E-56 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS17400 0a3cd38e7f36b4c4c6bbdf165babae91 299 Pfam PF09588 YqaJ-like viral recombinase domain 17 129 1.6E-8 T 28-03-2018 IPR019080 YqaJ viral recombinase A21D_RS17400 0a3cd38e7f36b4c4c6bbdf165babae91 299 SUPERFAMILY SSF52980 17 186 5.15E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS17400 0a3cd38e7f36b4c4c6bbdf165babae91 299 Gene3D G3DSA:3.90.320.10 8 198 3.0E-28 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A21D_RS19095 fa1a7aeb02aa49eb66e75168da28c45e 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 91 3.9E-23 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like A21D_RS19095 fa1a7aeb02aa49eb66e75168da28c45e 98 Gene3D G3DSA:1.10.287.1060 1 97 3.8E-18 T 28-03-2018 A21D_RS19095 fa1a7aeb02aa49eb66e75168da28c45e 98 Pfam PF06013 Proteins of 100 residues with WXG 4 89 3.1E-23 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like A21D_RS19095 fa1a7aeb02aa49eb66e75168da28c45e 98 SUPERFAMILY SSF140453 3 96 8.76E-22 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 SUPERFAMILY SSF58104 412 680 1.15E-66 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 SUPERFAMILY SSF58104 353 379 1.15E-66 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 SMART SM00283 406 681 7.4E-68 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Gene3D G3DSA:3.30.450.20 53 190 4.3E-24 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Pfam PF02743 Cache domain 60 285 2.0E-41 T 28-03-2018 IPR033479 Double Cache domain 1 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 SUPERFAMILY SSF103190 98 213 4.12E-14 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Pfam PF00672 HAMP domain 325 373 6.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Gene3D G3DSA:1.10.287.950 435 682 2.0E-53 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Gene3D G3DSA:3.30.450.20 191 300 6.3E-27 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 469 633 2.5E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 Gene3D G3DSA:1.10.287.950 349 434 3.0E-11 T 28-03-2018 A21D_RS07970 0305832dd708e9b9f8edce5f2ea9fd3b 682 SMART SM00304 324 377 1.0E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS11755 395497167d3c01d5a0a7ed618212498e 156 Gene3D G3DSA:3.40.30.10 1 154 3.5E-42 T 28-03-2018 A21D_RS11755 395497167d3c01d5a0a7ed618212498e 156 PIRSF PIRSF000239 1 154 2.1E-31 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS11755 395497167d3c01d5a0a7ed618212498e 156 Pfam PF00578 AhpC/TSA family 5 133 6.8E-43 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS11755 395497167d3c01d5a0a7ed618212498e 156 SUPERFAMILY SSF52833 3 153 5.21E-54 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 Pfam PF13476 AAA domain 37 87 2.8E-10 T 28-03-2018 A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 SUPERFAMILY SSF52540 39 223 2.35E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 Gene3D G3DSA:3.40.50.300 120 237 2.8E-12 T 28-03-2018 A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 Gene3D G3DSA:3.40.50.300 30 119 4.7E-9 T 28-03-2018 A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 153 209 6.7E-9 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS07530 a8c220fa31f1d41ae2244b6df5a243c4 253 SMART SM00382 44 222 2.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 301 8.2E-31 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Pfam PF01565 FAD binding domain 39 166 1.3E-27 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Gene3D G3DSA:3.90.78.10 205 301 3.4E-31 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Gene3D G3DSA:3.30.465.10 94 204 9.7E-37 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 SUPERFAMILY SSF56176 7 196 2.25E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 26 302 1.4E-74 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Gene3D G3DSA:3.30.43.10 15 88 2.1E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 306 91.682 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03005 42f1e89219d8eab1aa106cb039ee7840 306 SUPERFAMILY SSF56194 199 303 1.24E-39 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03505 395b9bd3897f95f09c250f46a7dc4364 93 SUPERFAMILY SSF46689 5 90 3.67E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS03505 395b9bd3897f95f09c250f46a7dc4364 93 Pfam PF01527 Transposase 3 76 3.8E-17 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A21D_RS03505 395b9bd3897f95f09c250f46a7dc4364 93 Gene3D G3DSA:1.10.10.60 9 89 1.6E-20 T 28-03-2018 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 35.416 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 3.8E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 3.8E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 3.8E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 3.8E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 3.8E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 SUPERFAMILY SSF52374 3 157 7.17E-43 T 28-03-2018 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 Gene3D G3DSA:3.40.50.620 2 159 2.4E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 Pfam PF01467 Cytidylyltransferase-like 6 134 3.0E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 88 8.0E-4 T 28-03-2018 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 158 9.8E-62 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A21D_RS18480 83bbe6c01045cb180ebafda215bfd9bc 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 64 5.3E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS17130 b1cbd835f3865d482b8b384f1b0ed308 160 PIRSF PIRSF021441 1 159 1.9E-59 T 28-03-2018 IPR031306 CcdC protein A21D_RS17130 b1cbd835f3865d482b8b384f1b0ed308 160 Pfam PF07301 Protein of unknown function (DUF1453) 6 148 6.7E-53 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 174 369 1.4E-68 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 SUPERFAMILY SSF52402 173 381 2.65E-51 T 28-03-2018 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Gene3D G3DSA:3.30.70.1510 5 80 7.9E-22 T 28-03-2018 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 SUPERFAMILY SSF143437 3 172 1.15E-46 T 28-03-2018 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 397 152.326 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Pfam PF02926 THUMP domain 30 161 1.0E-18 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Gene3D G3DSA:3.30.2300.10 81 162 8.6E-20 T 28-03-2018 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 SMART SM00981 74 164 8.3E-16 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 371 3.7E-121 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A21D_RS14420 5f6a6239c17a06fb2ca0afc2a0cc4347 397 Gene3D G3DSA:3.40.50.620 174 395 2.7E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 197 4.5E-56 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Gene3D G3DSA:2.40.50.140 1 65 5.1E-23 T 28-03-2018 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 SUPERFAMILY SSF50249 1 62 3.48E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 SUPERFAMILY SSF47781 64 131 1.96E-19 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Pfam PF01330 RuvA N terminal domain 1 61 7.3E-22 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 SMART SM00278 107 126 7.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 SMART SM00278 72 91 7.9 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Gene3D G3DSA:1.10.8.10 164 196 1.1E-8 T 28-03-2018 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 SUPERFAMILY SSF46929 150 197 4.84E-7 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 197 29.224 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Gene3D G3DSA:1.10.150.20 66 119 1.9E-13 T 28-03-2018 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Pfam PF07499 RuvA, C-terminal domain 152 197 7.3E-10 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Pfam PF14520 Helix-hairpin-helix domain 71 128 1.8E-13 T 28-03-2018 A21D_RS15265 95931573ee8a1b9df6bb3ccfc9f4bf4f 199 Gene3D G3DSA:1.10.150.20 120 163 0.22 T 28-03-2018 A21D_RS16845 dc9e0be550a3a58216950144bae7ba1b 204 SUPERFAMILY SSF109604 1 197 4.83E-62 T 28-03-2018 A21D_RS16845 dc9e0be550a3a58216950144bae7ba1b 204 SMART SM00471 22 134 3.5E-10 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS16845 dc9e0be550a3a58216950144bae7ba1b 204 Pfam PF01966 HD domain 27 124 3.1E-11 T 28-03-2018 IPR006674 HD domain A21D_RS16845 dc9e0be550a3a58216950144bae7ba1b 204 Gene3D G3DSA:1.10.3210.10 1 198 2.9E-25 T 28-03-2018 A21D_RS18345 0e587ea31486d3021efef837309ef7cc 269 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 36 266 8.5E-55 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A21D_RS18345 0e587ea31486d3021efef837309ef7cc 269 Gene3D G3DSA:3.60.140.10 2 268 1.4E-78 T 28-03-2018 A21D_RS18345 0e587ea31486d3021efef837309ef7cc 269 SUPERFAMILY SSF64438 18 266 1.08E-76 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A21D_RS18345 0e587ea31486d3021efef837309ef7cc 269 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 30 265 1.2E-72 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 479 554 2.2E-5 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 620 697 0.0025 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 714 790 4.5E-13 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 413 478 4.4E-6 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 555 619 0.071 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 338 412 2.6E-5 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:2.40.50.110 248 337 2.6E-6 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 SMART SM00287 736 807 6.3E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 SMART SM00287 418 481 2.6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 SMART SM00287 278 339 1.5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 SMART SM00047 829 985 4.0E-38 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Gene3D G3DSA:1.10.530.10 825 979 1.6E-26 T 28-03-2018 A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Pfam PF08239 Bacterial SH3 domain 745 788 7.3E-9 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS04250 d5cecdfd1f041d9aa22ac21864502af1 990 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 842 974 1.0E-10 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 SMART SM00493 4 77 4.3E-4 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 Pfam PF13662 Toprim domain 4 64 4.9E-6 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 Gene3D G3DSA:3.40.1360.20 1 127 2.4E-20 T 28-03-2018 A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 176 1.3E-54 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 180 30.559 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 SUPERFAMILY SSF110455 2 113 6.54E-34 T 28-03-2018 A21D_RS06800 a63a2064c64a976de03380d4b62e396b 192 Pfam PF13331 Domain of unknown function (DUF4093) 94 178 1.5E-27 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain A21D_RS05640 0d1772a3f7cecae9bf5c43e9d570e4f7 252 Gene3D G3DSA:3.20.20.370 46 252 9.8E-46 T 28-03-2018 A21D_RS05640 0d1772a3f7cecae9bf5c43e9d570e4f7 252 Pfam PF01522 Polysaccharide deacetylase 51 173 2.7E-18 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS05640 0d1772a3f7cecae9bf5c43e9d570e4f7 252 SUPERFAMILY SSF88713 15 242 2.97E-52 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS05640 0d1772a3f7cecae9bf5c43e9d570e4f7 252 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 52 241 2.5E-78 T 28-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 318 5.2E-97 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 SUPERFAMILY SSF53067 4 320 3.92E-70 T 28-03-2018 A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 ProSitePatterns PS01125 ROK family signature. 138 165 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 Gene3D G3DSA:3.30.420.40 1 123 2.7E-30 T 28-03-2018 A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 Pfam PF00480 ROK family 6 316 2.9E-76 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS15920 fb652c471f08bd7175baa50d16fdb10c 327 Gene3D G3DSA:3.30.420.40 124 327 2.3E-60 T 28-03-2018 A21D_RS05280 81a695552a891faa582f18d3b5cde4fa 219 SMART SM00382 31 215 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05280 81a695552a891faa582f18d3b5cde4fa 219 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05280 81a695552a891faa582f18d3b5cde4fa 219 Gene3D G3DSA:3.40.50.300 1 218 1.6E-59 T 28-03-2018 A21D_RS05280 81a695552a891faa582f18d3b5cde4fa 219 Pfam PF00005 ABC transporter 22 167 3.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05280 81a695552a891faa582f18d3b5cde4fa 219 SUPERFAMILY SSF52540 3 216 7.1E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 SUPERFAMILY SSF51735 1 104 1.24E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 Pfam PF14824 Sirohaem biosynthesis protein central 118 144 3.6E-7 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 Pfam PF13241 Putative NAD(P)-binding 6 114 9.2E-23 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 Gene3D G3DSA:3.40.50.720 3 119 1.9E-16 T 28-03-2018 A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 Gene3D G3DSA:3.30.160.110 120 146 4.1E-10 T 28-03-2018 A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 188 3.2E-30 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A21D_RS07470 c5d27743d8877cfece04c38b15a562b5 213 SUPERFAMILY SSF75615 110 194 2.22E-16 T 28-03-2018 A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 SUPERFAMILY SSF53613 8 320 2.18E-74 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 6 324 52.547 T 28-03-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 9 320 9.3E-124 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 Gene3D G3DSA:2.20.150.10 20 43 9.5E-15 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 Pfam PF00294 pfkB family carbohydrate kinase 11 312 9.9E-64 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 Gene3D G3DSA:3.40.1190.20 44 325 8.2E-55 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS01970 87e78a9ebe234e6e3584bd2203ad87ac 325 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 264 277 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 SUPERFAMILY SSF46689 4 81 4.37E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 Gene3D G3DSA:1.10.10.60 1 58 6.9E-16 T 28-03-2018 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 4.4E-58 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 Gene3D G3DSA:1.10.357.10 59 191 1.0E-20 T 28-03-2018 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.3E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS14790 4ad9b7f6510cc8c2bab9326c4feadde0 194 SUPERFAMILY SSF48498 79 191 3.48E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS18420 f28617e321df799cdb5dac744fe01684 122 Hamap MF_00910 Cell division protein FtsL [ftsL]. 36 118 13.328 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A21D_RS18420 f28617e321df799cdb5dac744fe01684 122 Pfam PF04977 Septum formation initiator 45 104 1.8E-7 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A21D_RS18420 f28617e321df799cdb5dac744fe01684 122 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 36 117 1.4E-16 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A21D_RS18420 f28617e321df799cdb5dac744fe01684 122 Gene3D G3DSA:1.20.5.1000 48 119 2.2E-4 T 28-03-2018 A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 SUPERFAMILY SSF51206 26 147 9.3E-30 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 Pfam PF00027 Cyclic nucleotide-binding domain 33 115 3.1E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 SUPERFAMILY SSF46785 149 223 1.05E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 Gene3D G3DSA:2.60.120.10 9 147 5.9E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 Pfam PF13545 Crp-like helix-turn-helix domain 168 222 3.9E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 SMART SM00419 171 219 1.3E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS07935 11ee69431ae056c4a5b05fce6e350ccc 225 Gene3D G3DSA:1.10.10.10 148 224 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19125 16f6fdfabe71861e294edd0b2b817d56 449 Pfam PF13416 Bacterial extracellular solute-binding protein 60 374 3.1E-53 T 28-03-2018 A21D_RS19125 16f6fdfabe71861e294edd0b2b817d56 449 SUPERFAMILY SSF53850 42 437 9.32E-82 T 28-03-2018 A21D_RS19125 16f6fdfabe71861e294edd0b2b817d56 449 Gene3D G3DSA:3.40.190.10 42 230 7.4E-36 T 28-03-2018 A21D_RS19125 16f6fdfabe71861e294edd0b2b817d56 449 Gene3D G3DSA:3.40.190.10 231 394 2.8E-16 T 28-03-2018 A21D_RS19125 16f6fdfabe71861e294edd0b2b817d56 449 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 153 170 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 A21D_RS12340 db68482667b2115e3924fde3749f2165 265 SMART SM00382 41 241 4.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12340 db68482667b2115e3924fde3749f2165 265 Gene3D G3DSA:3.40.50.300 2 262 4.0E-71 T 28-03-2018 A21D_RS12340 db68482667b2115e3924fde3749f2165 265 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS12340 db68482667b2115e3924fde3749f2165 265 Pfam PF00005 ABC transporter 33 182 1.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS12340 db68482667b2115e3924fde3749f2165 265 SUPERFAMILY SSF52540 5 254 2.31E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00865 ba8d24f681e229f9b6cfed7f5e5ef16c 87 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 82 5.7E-12 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal A21D_RS00865 ba8d24f681e229f9b6cfed7f5e5ef16c 87 Gene3D G3DSA:1.10.287.1160 53 82 8.5E-10 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A21D_RS00865 ba8d24f681e229f9b6cfed7f5e5ef16c 87 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 84 1.3E-12 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A21D_RS00865 ba8d24f681e229f9b6cfed7f5e5ef16c 87 SUPERFAMILY SSF101498 1 84 2.48E-16 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 SUPERFAMILY SSF52540 3 208 3.85E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 Gene3D G3DSA:3.40.50.300 292 447 2.9E-18 T 28-03-2018 A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 Gene3D G3DSA:3.40.50.10810 7 287 1.0E-24 T 28-03-2018 A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 SUPERFAMILY SSF52540 121 178 1.13E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 SUPERFAMILY SSF52540 297 453 1.13E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 SMART SM00487 2 194 1.1E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 Pfam PF00271 Helicase conserved C-terminal domain 307 410 1.4E-4 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS00085 15d1e709b8fdce657765e689a450a859 459 Pfam PF00176 SNF2 family N-terminal domain 28 266 6.5E-17 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 PIRSF PIRSF026546 1 207 6.8E-99 T 28-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 Pfam PF08279 HTH domain 6 58 1.8E-11 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 Gene3D G3DSA:1.10.10.10 1 60 1.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 Gene3D G3DSA:3.10.580.10 61 208 6.7E-23 T 28-03-2018 A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 SMART SM00116 150 201 0.025 T 28-03-2018 IPR000644 CBS domain A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 SMART SM00116 83 131 0.62 T 28-03-2018 IPR000644 CBS domain A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 SUPERFAMILY SSF54631 69 202 1.77E-21 T 28-03-2018 A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 SUPERFAMILY SSF46785 2 77 3.96E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 Pfam PF00571 CBS domain 144 201 5.8E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS15750 5e8211b49d28a5a0e61bf790908fe8a5 209 Pfam PF00571 CBS domain 84 130 4.1E-6 T 28-03-2018 IPR000644 CBS domain A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 Gene3D G3DSA:1.10.10.10 3 127 6.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 SMART SM00347 26 126 1.7E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 SUPERFAMILY SSF46785 7 137 3.25E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 3.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 3.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 3.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 3.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS03770 f64eca7913d5324d99bf38da48adf039 140 Pfam PF01047 MarR family 36 91 1.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS02290 ce3888ca266d5f93f3c3caeb98494f68 269 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02290 ce3888ca266d5f93f3c3caeb98494f68 269 Gene3D G3DSA:3.40.50.300 1 257 1.7E-63 T 28-03-2018 A21D_RS02290 ce3888ca266d5f93f3c3caeb98494f68 269 SMART SM00382 27 219 1.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS02290 ce3888ca266d5f93f3c3caeb98494f68 269 Pfam PF00005 ABC transporter 18 165 3.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS02290 ce3888ca266d5f93f3c3caeb98494f68 269 SUPERFAMILY SSF52540 2 229 1.86E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08940 85102edb82aa090199eeba44c4ba956a 392 SUPERFAMILY SSF103473 6 387 2.22E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS08940 85102edb82aa090199eeba44c4ba956a 392 Gene3D G3DSA:1.20.1250.20 200 381 2.0E-20 T 28-03-2018 A21D_RS08940 85102edb82aa090199eeba44c4ba956a 392 Gene3D G3DSA:1.20.1250.20 3 199 1.6E-34 T 28-03-2018 A21D_RS08940 85102edb82aa090199eeba44c4ba956a 392 Pfam PF07690 Major Facilitator Superfamily 17 324 1.5E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 Gene3D G3DSA:3.30.420.40 91 261 1.9E-60 T 28-03-2018 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 37.102 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 SUPERFAMILY SSF53067 125 254 7.77E-40 T 28-03-2018 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 Pfam PF03309 Type III pantothenate kinase 2 207 1.5E-72 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 SUPERFAMILY SSF53067 1 123 1.1E-35 T 28-03-2018 A21D_RS06655 49cda19e3d7b1d4f894472676dae6098 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 4.7E-79 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 286 1.4E-19 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 Gene3D G3DSA:3.40.50.1370 140 297 1.9E-41 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 SUPERFAMILY SSF53671 2 291 5.63E-80 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 206 215 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 251 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 284 1.9E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 291 35.643 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 242 251 8.0E-21 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 8.0E-21 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 277 8.0E-21 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 8.0E-21 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 Gene3D G3DSA:3.40.50.1370 1 139 6.1E-43 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 289 6.6E-84 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18295 ddc84776735dc01a3c8ef3721812859e 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 6.9E-37 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Gene3D G3DSA:3.40.50.620 41 168 1.6E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 633 1.8E-216 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 SUPERFAMILY SSF50677 202 393 2.83E-60 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 8.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 8.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 8.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 8.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 8.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Gene3D G3DSA:3.90.740.10 204 489 1.1E-96 T 28-03-2018 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Pfam PF06827 Zinc finger found in FPG and IleRS 882 911 4.1E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Gene3D G3DSA:3.30.2320.20 793 880 1.9E-22 T 28-03-2018 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 913 20.907 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 SUPERFAMILY SSF47323 644 915 2.99E-78 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 SUPERFAMILY SSF52374 393 640 2.21E-149 T 28-03-2018 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 SUPERFAMILY SSF52374 1 201 2.21E-149 T 28-03-2018 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 833 0.0 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Gene3D G3DSA:1.10.730.10 570 790 5.7E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS18315 53ee81ca688aeb5e8923009cadcb5eb8 918 Pfam PF08264 Anticodon-binding domain of tRNA 677 831 9.1E-31 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 147 5.4E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 9.2E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 9.2E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 9.2E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 SMART SM00226 2 149 5.4E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 Gene3D G3DSA:3.40.50.2300 1 157 2.4E-45 T 28-03-2018 A21D_RS11545 7b453ba316f7e086af571ff9909a3003 157 SUPERFAMILY SSF52788 1 150 2.35E-44 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 3.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 3.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 20 262 7.4E-86 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 19 263 36.471 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 SUPERFAMILY SSF53474 2 262 2.81E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 Gene3D G3DSA:3.40.50.1820 8 264 9.5E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS14080 2bad9260428e51f81949683c9aa6e4eb 266 Pfam PF00561 alpha/beta hydrolase fold 19 251 5.9E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 Gene3D G3DSA:3.40.50.300 1 83 9.1E-14 T 28-03-2018 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 Gene3D G3DSA:1.10.8.60 84 160 3.3E-25 T 28-03-2018 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 Pfam PF02954 Bacterial regulatory protein, Fis family 178 217 4.3E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 200 220 8.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 183 200 8.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 124 133 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 SUPERFAMILY SSF46689 124 219 4.26E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 Gene3D G3DSA:1.10.10.60 161 221 5.3E-16 T 28-03-2018 A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 SUPERFAMILY SSF52540 2 153 4.41E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02195 e8f18b8b5daaefe4909c105284dba83c 222 Pfam PF00158 Sigma-54 interaction domain 2 77 9.5E-29 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 Gene3D G3DSA:3.40.50.300 1 247 2.1E-60 T 28-03-2018 A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 SUPERFAMILY SSF52540 2 221 4.28E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 Pfam PF13732 Domain of unknown function (DUF4162) 211 293 8.0E-19 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 SMART SM00382 26 205 1.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13040 8423ce0a962f7128a9c12bcd83de7fe2 298 Pfam PF00005 ABC transporter 18 157 1.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08685 836c6aabfc3809389f3007efafe6be59 117 Pfam PF03788 LrgA family 14 103 4.1E-28 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 Pfam PF01037 Lrp/AsnC ligand binding domain 70 140 8.9E-18 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A21D_RS01250 fbb4b340975473249480eb743009cc58 149 SUPERFAMILY SSF46785 2 62 8.67E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01250 fbb4b340975473249480eb743009cc58 149 Pfam PF13404 AsnC-type helix-turn-helix domain 3 43 5.9E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 SMART SM00344 3 109 4.5E-37 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 Gene3D G3DSA:1.10.10.10 1 54 4.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01250 fbb4b340975473249480eb743009cc58 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A21D_RS01250 fbb4b340975473249480eb743009cc58 149 SUPERFAMILY SSF54909 65 147 2.82E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS01250 fbb4b340975473249480eb743009cc58 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.5E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.5E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.5E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A21D_RS01250 fbb4b340975473249480eb743009cc58 149 Gene3D G3DSA:3.30.70.920 55 149 2.8E-22 T 28-03-2018 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 SUPERFAMILY SSF55347 131 330 1.42E-69 T 28-03-2018 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 1.2E-33 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 SMART SM00859 8 123 1.2E-41 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 PIRSF PIRSF000148 6 348 1.6E-125 T 28-03-2018 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 329 1.7E-54 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 Gene3D G3DSA:3.30.360.10 143 326 1.7E-67 T 28-03-2018 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 345 8.8E-154 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 343 36.909 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 SUPERFAMILY SSF51735 7 159 9.02E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS17670 6b527ddbdbcd3cf0b78b730f3338fb35 350 Gene3D G3DSA:3.40.50.720 3 142 1.5E-36 T 28-03-2018 A21D_RS00350 4efaf7b281742e9f0c49f860bb06ad9b 418 Gene3D G3DSA:1.20.5.170 25 130 1.2E-8 T 28-03-2018 A21D_RS00350 4efaf7b281742e9f0c49f860bb06ad9b 418 SUPERFAMILY SSF54001 293 416 4.25E-41 T 28-03-2018 A21D_RS00350 4efaf7b281742e9f0c49f860bb06ad9b 418 Gene3D G3DSA:1.10.287.620 156 286 0.0081 T 28-03-2018 A21D_RS00350 4efaf7b281742e9f0c49f860bb06ad9b 418 Pfam PF00877 NlpC/P60 family 312 414 1.5E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A21D_RS00350 4efaf7b281742e9f0c49f860bb06ad9b 418 Gene3D G3DSA:3.90.1720.10 297 417 3.4E-39 T 28-03-2018 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 109 8.4E-13 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 Pfam PF00367 phosphotransferase system, EIIB 10 42 1.3E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 SUPERFAMILY SSF55604 7 79 1.83E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 Pfam PF02378 Phosphotransferase system, EIIC 110 400 1.8E-37 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 Gene3D G3DSA:3.30.1360.60 5 82 3.0E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS01665 4bbd0fd808ef2381b14c52160dd9f51b 465 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 454 6.2E-180 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 Gene3D G3DSA:1.10.10.10 1 83 8.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 SUPERFAMILY SSF53850 89 293 3.71E-41 T 28-03-2018 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 Gene3D G3DSA:3.40.190.10 180 267 1.5E-18 T 28-03-2018 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 Gene3D G3DSA:3.40.190.10 88 179 8.8E-26 T 28-03-2018 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 Pfam PF03466 LysR substrate binding domain 90 292 1.4E-45 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 SUPERFAMILY SSF46785 3 111 6.67E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS08145 99a698e7e9fe3f771f20285b3534f104 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 SUPERFAMILY SSF160240 218 291 1.96E-9 T 28-03-2018 A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 Gene3D G3DSA:3.30.70.1350 216 296 8.8E-14 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 SUPERFAMILY SSF161111 19 215 2.35E-56 T 28-03-2018 A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 Gene3D G3DSA:1.20.1510.10 18 214 4.0E-59 T 28-03-2018 A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 293 6.3E-94 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A21D_RS18740 f416aeee93c93a65a2d0de22e287fdaf 306 Pfam PF01545 Cation efflux family 23 214 1.4E-48 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 Pfam PF12836 Helix-hairpin-helix motif 139 199 1.3E-21 T 28-03-2018 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 SUPERFAMILY SSF47781 133 200 2.11E-26 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 138 199 5.9E-25 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 Pfam PF10531 SLBB domain 65 112 5.4E-13 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 Gene3D G3DSA:1.10.150.310 158 202 2.0E-16 T 28-03-2018 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 SMART SM00278 179 198 1.5 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 SMART SM00278 149 168 0.18 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A21D_RS15575 aa98203131f288feb60d2c11ff364b79 202 Gene3D G3DSA:3.10.560.10 46 157 5.3E-14 T 28-03-2018 A21D_RS19365 30b0e85a1c8f8e4e439136c3686bb6c5 129 SUPERFAMILY SSF55331 2 124 5.13E-33 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily A21D_RS19365 30b0e85a1c8f8e4e439136c3686bb6c5 129 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 125 1.6E-28 T 28-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 A21D_RS19365 30b0e85a1c8f8e4e439136c3686bb6c5 129 Gene3D G3DSA:3.30.429.10 1 126 8.9E-34 T 28-03-2018 A21D_RS05175 7c4027af93e503a23d3d7b08dfe1206d 470 Gene3D G3DSA:3.40.50.1820 5 304 2.3E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05175 7c4027af93e503a23d3d7b08dfe1206d 470 SUPERFAMILY SSF53474 141 276 3.1E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05175 7c4027af93e503a23d3d7b08dfe1206d 470 SUPERFAMILY SSF53474 29 69 3.1E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05175 7c4027af93e503a23d3d7b08dfe1206d 470 Pfam PF01764 Lipase (class 3) 64 260 3.3E-6 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A21D_RS18150 dec9e8839d50dc85217853604a04752e 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 2.9E-36 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 A21D_RS02450 47b4b7b9061c38d4339aca043f3f390c 96 Gene3D G3DSA:3.30.70.260 1 88 6.7E-4 T 28-03-2018 A21D_RS14045 811767b9c5f49ba7cf142085e684f6a5 195 Pfam PF12822 ECF transporter, substrate-specific component 10 178 9.3E-21 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A21D_RS14045 811767b9c5f49ba7cf142085e684f6a5 195 PIRSF PIRSF037778 4 190 9.6E-43 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 A21D_RS07440 384d6e83c78441c0aa0ac3273a857cab 104 SUPERFAMILY SSF103481 6 101 2.22E-13 T 28-03-2018 A21D_RS07440 384d6e83c78441c0aa0ac3273a857cab 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.0E-20 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 Gene3D G3DSA:3.20.20.140 68 349 4.6E-96 T 28-03-2018 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 35 375 7.1E-92 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 SUPERFAMILY SSF51338 349 382 9.45E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 SUPERFAMILY SSF51338 1 52 9.45E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 SUPERFAMILY SSF51556 53 349 1.28E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 Gene3D G3DSA:2.30.40.10 1 67 2.9E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 PIRSF PIRSF038994 4 382 8.0E-114 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A21D_RS04085 9bec95bcdd165bc626d72874e399eb4a 385 Pfam PF01979 Amidohydrolase family 50 376 3.3E-17 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 176 230 1.0E-11 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 SUPERFAMILY SSF55120 2 227 2.85E-77 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 175 4.1E-57 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 212 3.6E-77 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 295 18.711 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS17715 9bf08ea52610ab77e0206002c2df7ea6 297 Gene3D G3DSA:3.30.2350.10 1 225 6.6E-79 T 28-03-2018 A21D_RS15290 2aa66ff0f32237f7887b37288204f25e 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 4.9E-28 T 28-03-2018 IPR003849 Preprotein translocase YajC A21D_RS15290 2aa66ff0f32237f7887b37288204f25e 86 SMART SM01323 2 84 1.6E-40 T 28-03-2018 IPR003849 Preprotein translocase YajC A21D_RS15290 2aa66ff0f32237f7887b37288204f25e 86 Pfam PF02699 Preprotein translocase subunit 6 81 6.2E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC A21D_RS15290 2aa66ff0f32237f7887b37288204f25e 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 3.2E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC A21D_RS15290 2aa66ff0f32237f7887b37288204f25e 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 42 3.2E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 SUPERFAMILY SSF52279 373 607 8.63E-55 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 253 270 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 SMART SM01217 641 710 3.2E-26 T 28-03-2018 IPR026891 Fibronectin type III-like domain A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Pfam PF14310 Fibronectin type III-like domain 641 710 3.1E-17 T 28-03-2018 IPR026891 Fibronectin type III-like domain A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Gene3D G3DSA:2.60.40.10 605 722 3.6E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 14 332 1.4E-75 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 373 604 3.5E-55 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Gene3D G3DSA:3.40.50.1700 357 604 1.7E-79 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 SUPERFAMILY SSF51445 5 371 2.74E-107 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 PRINTS PR00133 Glycosyl hydrolase family 3 signature 99 118 1.4E-23 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 PRINTS PR00133 Glycosyl hydrolase family 3 signature 145 161 1.4E-23 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 PRINTS PR00133 Glycosyl hydrolase family 3 signature 183 199 1.4E-23 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 PRINTS PR00133 Glycosyl hydrolase family 3 signature 253 271 1.4E-23 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 PRINTS PR00133 Glycosyl hydrolase family 3 signature 80 96 1.4E-23 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS04875 2df56f57fd2a13c3c5be5173c13e6215 726 Gene3D G3DSA:3.20.20.300 2 356 5.3E-110 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS05260 b437d9cda47510a09bfc40036428f8eb 171 PIRSF PIRSF005384 1 148 4.4E-48 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05260 b437d9cda47510a09bfc40036428f8eb 171 SUPERFAMILY SSF89623 1 144 7.85E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05260 b437d9cda47510a09bfc40036428f8eb 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 141 4.9E-41 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05260 b437d9cda47510a09bfc40036428f8eb 171 Pfam PF02502 Ribose/Galactose Isomerase 3 141 6.2E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05260 b437d9cda47510a09bfc40036428f8eb 171 Gene3D G3DSA:3.40.1400.10 1 171 7.3E-54 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS08465 60c42b67395912bcd6b90bad5e7d5d68 304 SUPERFAMILY SSF52540 6 215 9.19E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08465 60c42b67395912bcd6b90bad5e7d5d68 304 SMART SM00382 30 211 7.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08465 60c42b67395912bcd6b90bad5e7d5d68 304 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08465 60c42b67395912bcd6b90bad5e7d5d68 304 Pfam PF00005 ABC transporter 22 162 5.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08465 60c42b67395912bcd6b90bad5e7d5d68 304 Gene3D G3DSA:3.40.50.300 3 248 4.3E-58 T 28-03-2018 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Gene3D G3DSA:3.10.20.30 1 71 4.7E-18 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 547 5.9E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 5.9E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 5.9E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 465 493 5.9E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 508 521 5.9E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 SUPERFAMILY SSF55186 68 243 9.55E-62 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Gene3D G3DSA:3.30.980.10 72 147 3.6E-23 T 28-03-2018 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 SUPERFAMILY SSF55681 245 527 3.98E-92 T 28-03-2018 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Gene3D G3DSA:3.40.50.800 533 638 6.8E-30 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Gene3D G3DSA:3.30.930.10 223 532 7.2E-121 T 28-03-2018 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 635 34.863 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 3.8E-15 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Gene3D G3DSA:3.30.54.20 148 189 9.2E-19 T 28-03-2018 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Pfam PF02824 TGS domain 5 64 6.7E-16 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Pfam PF03129 Anticodon binding domain 542 631 9.7E-23 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 632 2.7E-230 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 SUPERFAMILY SSF52954 531 634 3.78E-31 T 28-03-2018 IPR004154 Anticodon-binding A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 SMART SM00863 172 221 8.9E-22 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 529 1.1E-37 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS09635 6588b1f984efc709d445c260b77840a8 638 SUPERFAMILY SSF81271 5 64 6.76E-15 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 Gene3D G3DSA:1.10.10.60 43 78 2.3E-7 T 28-03-2018 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 SUPERFAMILY SSF46689 6 75 2.94E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 Gene3D G3DSA:1.10.10.60 4 42 1.5E-14 T 28-03-2018 A21D_RS14405 a9f5e35cb0293f777c2e5cf4dd95bbed 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 1.8E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS19315 32d9afd4a10cbddbfa74c297bd3c3016 287 Gene3D G3DSA:3.40.50.300 3 220 7.9E-47 T 28-03-2018 A21D_RS19315 32d9afd4a10cbddbfa74c297bd3c3016 287 Pfam PF00005 ABC transporter 20 151 9.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS19315 32d9afd4a10cbddbfa74c297bd3c3016 287 SUPERFAMILY SSF52540 6 204 1.38E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS19315 32d9afd4a10cbddbfa74c297bd3c3016 287 SMART SM00382 29 199 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 SUPERFAMILY SSF46894 156 214 8.5E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 Gene3D G3DSA:3.40.50.2300 1 143 1.9E-11 T 28-03-2018 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 209 5.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 Gene3D G3DSA:1.10.10.10 155 216 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 SMART SM00421 157 214 5.8E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS13765 f80dfc1da3b358d3c9e4d3f26f41be51 224 SUPERFAMILY SSF52172 1 124 1.49E-6 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS07390 1a2a65fa709f21a4866df20bc8dd2e73 438 Pfam PF07435 YycH protein 4 424 4.3E-69 T 28-03-2018 IPR009996 Regulatory protein YycH A21D_RS18840 3b214bfce35dcf22874a116634792b2d 159 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 153 8.7E-65 T 28-03-2018 IPR014203 Sporulation stage V, protein AC A21D_RS18840 3b214bfce35dcf22874a116634792b2d 159 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 32 149 2.0E-40 T 28-03-2018 IPR005562 SpoVA A21D_RS00995 9a4bc89313d72f8ab992375e10675acd 422 Gene3D G3DSA:1.20.1250.20 24 220 1.6E-34 T 28-03-2018 A21D_RS00995 9a4bc89313d72f8ab992375e10675acd 422 Pfam PF07690 Major Facilitator Superfamily 268 403 1.3E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS00995 9a4bc89313d72f8ab992375e10675acd 422 Pfam PF07690 Major Facilitator Superfamily 36 262 6.4E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS00995 9a4bc89313d72f8ab992375e10675acd 422 SUPERFAMILY SSF103473 19 409 7.32E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS00995 9a4bc89313d72f8ab992375e10675acd 422 Gene3D G3DSA:1.20.1250.20 227 422 1.1E-22 T 28-03-2018 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 SUPERFAMILY SSF100950 74 227 2.6E-34 T 28-03-2018 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 Gene3D G3DSA:1.10.10.10 2 58 4.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.1E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 SUPERFAMILY SSF46785 3 60 1.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 SMART SM00420 6 58 4.7E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 SMART SM01134 73 231 2.3E-65 T 28-03-2018 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 Pfam PF00455 DeoR C terminal sensor domain 75 229 8.4E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 Gene3D G3DSA:3.40.50.1360 65 243 2.4E-40 T 28-03-2018 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.8E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS03755 c61d865db0ff40d449a9af88b72d53d2 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.8E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS13560 6acb9bbc622d9bf87cfbf3ba8d37142c 230 Pfam PF04239 Protein of unknown function (DUF421) 83 198 2.2E-30 T 28-03-2018 IPR007353 Protein of unknown function DUF421 A21D_RS13560 6acb9bbc622d9bf87cfbf3ba8d37142c 230 Gene3D G3DSA:3.30.240.20 76 145 1.2E-21 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS13560 6acb9bbc622d9bf87cfbf3ba8d37142c 230 Gene3D G3DSA:3.30.240.20 165 219 2.5E-17 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS16225 4444b32c5bcdbb20d5f52c79344116cd 146 SUPERFAMILY SSF54593 9 140 1.03E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS16225 4444b32c5bcdbb20d5f52c79344116cd 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 122 1.7E-16 T 28-03-2018 A21D_RS16225 4444b32c5bcdbb20d5f52c79344116cd 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 11 137 4.6E-37 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A21D_RS16225 4444b32c5bcdbb20d5f52c79344116cd 146 Gene3D G3DSA:3.10.180.10 2 142 1.4E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 SUPERFAMILY SSF55816 277 463 2.88E-25 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 Pfam PF02872 5'-nucleotidase, C-terminal domain 292 427 9.2E-15 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 Gene3D G3DSA:3.60.21.10 5 284 2.2E-52 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PIRSF PIRSF036361 1 465 2.2E-164 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 Pfam PF00149 Calcineurin-like phosphoesterase 9 205 9.3E-5 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PRINTS PR01607 Apyrase family signature 169 186 2.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PRINTS PR01607 Apyrase family signature 3 21 2.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PRINTS PR01607 Apyrase family signature 329 352 2.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PRINTS PR01607 Apyrase family signature 188 211 2.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 PRINTS PR01607 Apyrase family signature 414 433 2.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 Gene3D G3DSA:3.90.780.10 285 464 6.3E-26 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS13845 91a85cc1781485dcb4c0d3aae6cd8cd4 465 SUPERFAMILY SSF56300 4 272 5.7E-62 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 Gene3D G3DSA:3.90.1150.10 288 395 1.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 SUPERFAMILY SSF53383 9 394 2.86E-109 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 Gene3D G3DSA:3.40.640.10 51 287 3.3E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 Pfam PF00155 Aminotransferase class I and II 43 383 1.7E-64 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS09060 206fa7721eda8b671f5e787284e56296 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 1.3E-192 T 28-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 Gene3D G3DSA:3.90.230.10 1 249 3.4E-80 T 28-03-2018 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 5.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 5.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 5.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 5.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 SUPERFAMILY SSF55920 1 246 2.36E-84 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 39.131 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 5 247 3.2E-92 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A21D_RS12940 fb8a3003048517a4badda930ee00a336 250 Pfam PF00557 Metallopeptidase family M24 11 239 1.9E-55 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS02100 56f0a39c7be584193a019aa675f99695 422 Pfam PF02447 GntP family permease 10 415 1.3E-21 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 141 258 1.2E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 SUPERFAMILY SSF54593 4 279 1.34E-37 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 Gene3D G3DSA:3.10.180.10 4 133 1.8E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 Gene3D G3DSA:3.10.180.10 134 290 7.7E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 Gene3D G3DSA:4.10.1270.10 291 325 8.3E-13 T 28-03-2018 A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 4 299 2.3E-133 T 28-03-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type A21D_RS19385 bf93b1c84007c75be572e78d2e6d95bf 326 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 236 257 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 SUPERFAMILY SSF101473 3 201 9.94E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 Pfam PF13684 Dihydroxyacetone kinase family 239 551 1.6E-122 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 SMART SM01120 36 201 1.9E-65 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 SMART SM01121 239 551 1.8E-182 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 Pfam PF02734 DAK2 domain 36 200 1.1E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A21D_RS18145 d5988540d41dbfa97f61849a59c794c2 551 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 551 8.2E-213 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV A21D_RS12760 a3804a210c6332289a8898cbcc1e8545 310 SMART SM00382 26 210 3.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12760 a3804a210c6332289a8898cbcc1e8545 310 Gene3D G3DSA:3.40.50.300 1 280 1.5E-63 T 28-03-2018 A21D_RS12760 a3804a210c6332289a8898cbcc1e8545 310 Pfam PF00005 ABC transporter 17 160 4.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS12760 a3804a210c6332289a8898cbcc1e8545 310 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS12760 a3804a210c6332289a8898cbcc1e8545 310 SUPERFAMILY SSF52540 2 220 3.03E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03895 de9b1dc44f232bfe500ab147a7d2ac41 268 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 1.1E-86 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A21D_RS03895 de9b1dc44f232bfe500ab147a7d2ac41 268 Gene3D G3DSA:3.40.1190.20 1 266 6.2E-50 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03895 de9b1dc44f232bfe500ab147a7d2ac41 268 SUPERFAMILY SSF53613 3 265 6.39E-70 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03895 de9b1dc44f232bfe500ab147a7d2ac41 268 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 260 3.1E-81 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.6E-51 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.789 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 Gene3D G3DSA:3.30.70.141 1 148 4.4E-58 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 SUPERFAMILY SSF54919 1 148 2.23E-62 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 6.8E-58 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS16605 0dc8b3ecddbeed68a56580dba0bfc30c 148 SMART SM00562 1 138 3.7E-90 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 Gene3D G3DSA:3.40.50.2300 1 125 1.0E-34 T 28-03-2018 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 Gene3D G3DSA:1.10.10.10 126 229 5.0E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04000 e545c038094109bcd105706be9c43d80 230 SUPERFAMILY SSF46894 128 224 3.4E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 223 8.2E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 SMART SM00862 152 223 9.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 SUPERFAMILY SSF52172 2 123 9.68E-39 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS04000 e545c038094109bcd105706be9c43d80 230 Pfam PF00072 Response regulator receiver domain 6 114 4.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS04000 e545c038094109bcd105706be9c43d80 230 SMART SM00448 3 113 1.6E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS19480 16130458b9ddfacc4037eef116965fee 609 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 236 593 5.0E-6 T 28-03-2018 A21D_RS19480 16130458b9ddfacc4037eef116965fee 609 Gene3D G3DSA:1.20.120.20 305 466 0.021 T 28-03-2018 A21D_RS19480 16130458b9ddfacc4037eef116965fee 609 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 180 2.9E-8 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A21D_RS19480 16130458b9ddfacc4037eef116965fee 609 Gene3D G3DSA:1.20.5.1230 467 597 5.6E-7 T 28-03-2018 A21D_RS19480 16130458b9ddfacc4037eef116965fee 609 Gene3D G3DSA:1.20.120.570 184 304 6.7E-5 T 28-03-2018 A21D_RS12485 d8b9d72612bf2ab10882ef3f013187af 270 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 146 223 3.3E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS12485 d8b9d72612bf2ab10882ef3f013187af 270 Gene3D G3DSA:3.40.50.1000 1 43 0.034 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12485 d8b9d72612bf2ab10882ef3f013187af 270 SUPERFAMILY SSF56784 1 257 8.52E-38 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12485 d8b9d72612bf2ab10882ef3f013187af 270 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 232 2.9E-23 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12485 d8b9d72612bf2ab10882ef3f013187af 270 Gene3D G3DSA:3.40.50.1000 112 266 1.6E-26 T 28-03-2018 IPR023214 HAD-like domain A21D_RS00340 6d5db6c3c3eed853c2e176e9bdeb755a 41 Pfam PF03471 Transporter associated domain 2 41 1.3E-5 T 28-03-2018 IPR005170 Transporter-associated domain A21D_RS00340 6d5db6c3c3eed853c2e176e9bdeb755a 41 Gene3D G3DSA:3.30.465.10 1 41 7.6E-6 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A21D_RS00340 6d5db6c3c3eed853c2e176e9bdeb755a 41 SUPERFAMILY SSF56176 2 40 1.28E-5 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 SUPERFAMILY SSF52540 326 569 8.99E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 SUPERFAMILY SSF90123 8 316 1.83E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 SMART SM00382 359 553 6.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 Pfam PF00664 ABC transporter transmembrane region 16 277 5.6E-22 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 Gene3D G3DSA:1.20.1560.10 3 318 4.9E-37 T 28-03-2018 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 Pfam PF00005 ABC transporter 350 499 1.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 Gene3D G3DSA:3.40.50.300 319 573 7.8E-65 T 28-03-2018 A21D_RS01635 0cfbd20f68b589bf738d98d486ee962f 574 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 541 2.2E-170 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A21D_RS07910 38ed1ab452cfa0344aa975d0e5f4ba80 294 Hamap MF_00729 Fructose-bisphosphate aldolase class 1 [fda]. 2 294 54.038 T 28-03-2018 IPR023014 Fructose-bisphosphate aldolase class I, Gram positive bacteria-type GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A21D_RS07910 38ed1ab452cfa0344aa975d0e5f4ba80 294 SUPERFAMILY SSF51569 2 294 2.62E-98 T 28-03-2018 A21D_RS07910 38ed1ab452cfa0344aa975d0e5f4ba80 294 Pfam PF00274 Fructose-bisphosphate aldolase class-I 10 214 5.5E-12 T 28-03-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS07910 38ed1ab452cfa0344aa975d0e5f4ba80 294 Gene3D G3DSA:3.20.20.70 2 294 7.4E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 Gene3D G3DSA:2.40.10.10 117 229 5.7E-27 T 28-03-2018 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 Gene3D G3DSA:2.40.10.10 230 343 3.0E-35 T 28-03-2018 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 SUPERFAMILY SSF50156 322 437 1.28E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 SUPERFAMILY SSF50494 125 336 2.97E-52 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 SMART SM00228 340 428 2.9E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 Pfam PF13365 Trypsin-like peptidase domain 154 302 8.9E-30 T 28-03-2018 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 Gene3D G3DSA:2.30.42.10 344 447 2.8E-26 T 28-03-2018 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 273 290 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 166 178 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 229 253 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 295 312 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 188 208 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 PRINTS PR00834 HtrA/DegQ protease family signature 385 397 7.6E-34 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS04015 437b17ced967cc2790aa3704a2433122 451 Pfam PF13180 PDZ domain 341 437 8.5E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 Gene3D G3DSA:3.40.250.10 82 188 9.5E-28 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 SMART SM00450 93 188 7.0E-22 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 Pfam PF00581 Rhodanese-like domain 95 183 8.4E-17 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 ProSitePatterns PS00380 Rhodanese signature 1. 118 129 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 9 33 - T 28-03-2018 IPR001455 TusA-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 SUPERFAMILY SSF52821 82 183 6.55E-31 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 Pfam PF01206 Sulfurtransferase TusA 8 75 1.0E-21 T 28-03-2018 IPR001455 TusA-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 SUPERFAMILY SSF64307 3 75 3.79E-23 T 28-03-2018 IPR001455 TusA-like domain A21D_RS11355 bc8ede7d7caef2a00444d9adc251c86d 190 Gene3D G3DSA:3.30.110.40 7 81 2.3E-27 T 28-03-2018 IPR001455 TusA-like domain A21D_RS03300 7a7e0284db1e6a45c704b4583436726a 321 Gene3D G3DSA:3.60.15.10 1 286 6.7E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03300 7a7e0284db1e6a45c704b4583436726a 321 SUPERFAMILY SSF56281 6 276 1.05E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03300 7a7e0284db1e6a45c704b4583436726a 321 SMART SM00849 25 230 5.3E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03300 7a7e0284db1e6a45c704b4583436726a 321 Pfam PF00753 Metallo-beta-lactamase superfamily 30 230 8.8E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS10715 6095c628ce8c3f2e95741646f55fda39 507 Pfam PF03553 Na+/H+ antiporter family 157 471 3.7E-61 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS16685 d189018718b51f828f361c24745e1bd8 228 Pfam PF04298 Putative neutral zinc metallopeptidase 8 223 8.1E-95 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase A21D_RS13460 5c4d74ddf7e5f75fd6e8b2198556346a 194 Gene3D G3DSA:3.40.630.30 4 167 4.2E-11 T 28-03-2018 A21D_RS13460 5c4d74ddf7e5f75fd6e8b2198556346a 194 SUPERFAMILY SSF55729 42 150 6.06E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS13460 5c4d74ddf7e5f75fd6e8b2198556346a 194 Pfam PF13508 Acetyltransferase (GNAT) domain 47 110 2.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 PIRSF PIRSF000151 1 417 1.0E-175 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 Gene3D G3DSA:3.40.605.10 237 417 2.8E-36 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 323 345 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 SUPERFAMILY SSF53720 2 416 4.84E-110 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 Gene3D G3DSA:3.40.605.10 1 236 3.3E-37 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 5 416 39.99 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 13 406 2.0E-164 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS01465 fc18cf6b0a15436a63d76b9ac7473c30 417 Pfam PF00171 Aldehyde dehydrogenase family 5 286 5.3E-13 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 Pfam PF00107 Zinc-binding dehydrogenase 166 287 1.0E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 SMART SM00829 6 323 3.7E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 SUPERFAMILY SSF50129 4 160 1.67E-32 T 28-03-2018 IPR011032 GroES-like A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 Gene3D G3DSA:3.90.180.10 1 326 8.9E-66 T 28-03-2018 A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 SUPERFAMILY SSF51735 127 291 2.1E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18870 9feff8a8651f0af9886f4064a938be56 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 86 1.1E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 352 1.4E-97 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 Gene3D G3DSA:3.90.1150.10 280 358 7.4E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 52.399 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 SUPERFAMILY SSF53383 5 354 5.09E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 Gene3D G3DSA:3.40.640.10 44 279 4.5E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS16630 0eb8068245eacc831bbf8cc54b2c34b1 363 Pfam PF00155 Aminotransferase class I and II 31 348 2.4E-54 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 Pfam PF00005 ABC transporter 31 180 2.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 SUPERFAMILY SSF52540 3 252 1.61E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 269 5.6E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 SMART SM00382 39 230 5.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 Gene3D G3DSA:3.40.50.300 1 294 7.8E-75 T 28-03-2018 A21D_RS01325 59f058105eb6d5c8c9927b2e68dfb37e 310 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 Gene3D G3DSA:3.40.605.10 5 279 1.3E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 Pfam PF00171 Aldehyde dehydrogenase family 33 494 5.2E-163 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 SUPERFAMILY SSF53720 12 499 3.14E-160 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 Gene3D G3DSA:3.40.309.10 280 481 9.4E-66 T 28-03-2018 A21D_RS00960 a5383ae6a201c43bce9e41f6531caf5a 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS05265 e5ac7228be35bad42fc2b02f81c05858 142 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 140 6.8E-34 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05265 e5ac7228be35bad42fc2b02f81c05858 142 SUPERFAMILY SSF89623 1 141 1.57E-40 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05265 e5ac7228be35bad42fc2b02f81c05858 142 PIRSF PIRSF005384 1 142 4.8E-42 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05265 e5ac7228be35bad42fc2b02f81c05858 142 Pfam PF02502 Ribose/Galactose Isomerase 3 138 3.0E-37 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS05265 e5ac7228be35bad42fc2b02f81c05858 142 Gene3D G3DSA:3.40.1400.10 1 142 1.4E-41 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 Pfam PF01467 Cytidylyltransferase-like 6 161 6.3E-33 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 Gene3D G3DSA:3.40.50.620 1 187 5.1E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 187 31.672 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 186 1.1E-59 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 6.2E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS15555 18e3d1d73d2afb3e186d045649ac099e 188 SUPERFAMILY SSF52374 1 187 5.0E-56 T 28-03-2018 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Pfam PF00326 Prolyl oligopeptidase family 456 666 4.5E-57 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Gene3D G3DSA:3.40.50.1820 385 666 4.6E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Pfam PF07676 WD40-like Beta Propeller Repeat 61 92 2.6E-7 T 28-03-2018 IPR011659 WD40-like Beta Propeller A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Pfam PF07676 WD40-like Beta Propeller Repeat 242 263 0.13 T 28-03-2018 IPR011659 WD40-like Beta Propeller A21D_RS12800 271b0720479c374bb37fe765a243c061 666 SUPERFAMILY SSF53474 409 666 5.5E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Gene3D G3DSA:2.130.10.150 16 76 1.8E-6 T 28-03-2018 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Gene3D G3DSA:2.130.10.150 77 289 6.1E-35 T 28-03-2018 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 Gene3D G3DSA:2.140.10.30 290 384 1.6E-4 T 28-03-2018 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 SUPERFAMILY SSF82171 175 403 3.14E-35 T 28-03-2018 A21D_RS12800 271b0720479c374bb37fe765a243c061 666 SUPERFAMILY SSF82171 16 129 3.14E-35 T 28-03-2018 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 SUPERFAMILY SSF53720 5 485 1.44E-150 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 Pfam PF00171 Aldehyde dehydrogenase family 17 481 4.4E-151 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 3 485 69.853 T 28-03-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 Gene3D G3DSA:3.40.309.10 268 463 2.8E-62 T 28-03-2018 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 485 4.5E-189 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 A21D_RS12635 4035c26330f7672bb007f7fff129cb79 486 Gene3D G3DSA:3.40.605.10 1 267 2.3E-86 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11110 df5703bd7fb362388d132148671e076b 219 SUPERFAMILY SSF51735 5 209 6.43E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11110 df5703bd7fb362388d132148671e076b 219 Pfam PF13460 NAD(P)H-binding 10 196 6.0E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11110 df5703bd7fb362388d132148671e076b 219 Gene3D G3DSA:3.40.50.720 4 219 6.7E-37 T 28-03-2018 A21D_RS04010 b66a1bab211123a2ac6494077e4a992a 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS04010 b66a1bab211123a2ac6494077e4a992a 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS04010 b66a1bab211123a2ac6494077e4a992a 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS04010 b66a1bab211123a2ac6494077e4a992a 409 SUPERFAMILY SSF53098 63 342 3.64E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS10040 5545adc2277271825ec475d86f213590 133 SUPERFAMILY SSF55874 22 126 2.05E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10040 5545adc2277271825ec475d86f213590 133 Gene3D G3DSA:3.30.565.10 7 129 4.0E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10040 5545adc2277271825ec475d86f213590 133 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 127 3.7E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10040 5545adc2277271825ec475d86f213590 133 SMART SM00387 34 133 6.6E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS09775 05f5edbd76da061051e26623a5af498f 473 Pfam PF03553 Na+/H+ antiporter family 162 454 1.6E-52 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS09775 05f5edbd76da061051e26623a5af498f 473 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 10 460 4.6E-122 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A21D_RS03695 192e5e73beda31245252a0aa242b5fa2 296 SMART SM00382 28 214 2.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03695 192e5e73beda31245252a0aa242b5fa2 296 Gene3D G3DSA:3.40.50.300 1 266 2.4E-36 T 28-03-2018 A21D_RS03695 192e5e73beda31245252a0aa242b5fa2 296 SUPERFAMILY SSF52540 4 218 9.94E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03695 192e5e73beda31245252a0aa242b5fa2 296 Pfam PF00005 ABC transporter 19 156 6.7E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS18685 8772c543ac89ec2958d4b5c7535c993b 69 Hamap MF_01553 UPF0356 protein . 1 69 20.398 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 A21D_RS18685 8772c543ac89ec2958d4b5c7535c993b 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 67 2.1E-26 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 A21D_RS18685 8772c543ac89ec2958d4b5c7535c993b 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 66 2.0E-17 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 A21D_RS09850 aedd692af63a31c594df28c57c8deea8 322 SMART SM00854 1 240 2.4E-74 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA A21D_RS09850 aedd692af63a31c594df28c57c8deea8 322 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 1 240 2.1E-68 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA A21D_RS09850 aedd692af63a31c594df28c57c8deea8 322 SUPERFAMILY SSF56300 17 285 1.35E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS09850 aedd692af63a31c594df28c57c8deea8 322 Gene3D G3DSA:3.60.21.10 3 309 6.0E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS15135 277368b3bb393c48d8673798d71b3205 472 Gene3D G3DSA:3.10.350.10 419 472 1.9E-8 T 28-03-2018 A21D_RS15135 277368b3bb393c48d8673798d71b3205 472 SUPERFAMILY SSF54106 423 467 1.27E-6 T 28-03-2018 IPR018392 LysM domain A21D_RS15135 277368b3bb393c48d8673798d71b3205 472 Pfam PF01476 LysM domain 426 467 9.3E-6 T 28-03-2018 IPR018392 LysM domain A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 Gene3D G3DSA:3.40.50.150 141 333 7.5E-30 T 28-03-2018 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 Pfam PF13411 MerR HTH family regulatory protein 2 68 3.1E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 Gene3D G3DSA:1.10.1660.10 56 140 2.2E-5 T 28-03-2018 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.6E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.6E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 SUPERFAMILY SSF46955 1 108 1.14E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 SMART SM00422 1 69 2.5E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 Gene3D G3DSA:1.10.1660.10 1 55 4.5E-20 T 28-03-2018 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 Pfam PF13649 Methyltransferase domain 183 272 1.2E-19 T 28-03-2018 A21D_RS08845 8dd7e476f0b67b9e8ec5db8cd15cb0b4 344 SUPERFAMILY SSF53335 137 331 2.76E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS15880 df419695c300562114122f4163712844 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 3.9E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15880 df419695c300562114122f4163712844 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.446 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15880 df419695c300562114122f4163712844 49 Pfam PF00471 Ribosomal protein L33 3 49 2.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15880 df419695c300562114122f4163712844 49 SUPERFAMILY SSF57829 1 49 1.22E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A21D_RS15880 df419695c300562114122f4163712844 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS05875 24c7cff4401c99199472ad745a99f2c7 106 SUPERFAMILY SSF54909 2 97 2.99E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS05875 24c7cff4401c99199472ad745a99f2c7 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 76 1.6E-14 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A21D_RS05875 24c7cff4401c99199472ad745a99f2c7 106 Gene3D G3DSA:3.30.70.100 1 105 1.5E-20 T 28-03-2018 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 2.8E-159 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 Gene3D G3DSA:3.40.50.720 7 149 7.2E-38 T 28-03-2018 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 Gene3D G3DSA:3.90.110.10 150 312 2.6E-49 T 28-03-2018 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.9E-30 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.9E-30 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.9E-30 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.9E-30 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.9E-30 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 SUPERFAMILY SSF56327 151 309 1.3E-53 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 5 312 46.921 T 28-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 2.1E-28 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 PIRSF PIRSF000102 2 312 6.3E-104 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 SUPERFAMILY SSF51735 7 147 2.5E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS14585 b8b60e7a75198bd3460c4296439e0f42 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.9E-41 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A21D_RS18600 70d56814286790e5f99569d417596f86 100 Pfam PF14036 YlaH-like protein 21 92 3.1E-23 T 28-03-2018 IPR025620 YlaH-like protein A21D_RS01560 2b97abef7c2a954b17394eadb45e96d3 194 Gene3D G3DSA:3.40.630.30 1 160 7.6E-18 T 28-03-2018 A21D_RS01560 2b97abef7c2a954b17394eadb45e96d3 194 Pfam PF13508 Acetyltransferase (GNAT) domain 45 134 2.0E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS01560 2b97abef7c2a954b17394eadb45e96d3 194 SUPERFAMILY SSF55729 2 138 1.25E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 SUPERFAMILY SSF54791 208 303 9.95E-16 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Pfam PF01966 HD domain 337 428 2.9E-17 T 28-03-2018 IPR006674 HD domain A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 SMART SM00471 332 438 3.8E-13 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 SUPERFAMILY SSF109604 316 467 8.3E-31 T 28-03-2018 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Gene3D G3DSA:1.10.3210.10 245 455 1.4E-35 T 28-03-2018 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Pfam PF12072 Domain of unknown function (DUF3552) 6 205 3.4E-75 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Hamap MF_00335 Ribonuclease Y [rny]. 5 520 25.825 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 SMART SM00322 208 275 1.2E-6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Gene3D G3DSA:3.30.300.20 153 244 5.1E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 Pfam PF00013 KH domain 213 270 2.4E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 TIGRFAM TIGR00277 HDIG: HDIG domain 332 409 1.5E-23 T 28-03-2018 IPR006675 HDIG domain A21D_RS17570 551222e4d795f1a99254b8d082f63048 520 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 9 520 3.1E-245 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A21D_RS19195 0a2c9bd663aa9b7a9e646fd8fcdf65e4 349 SUPERFAMILY SSF56235 115 328 6.4E-12 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS19195 0a2c9bd663aa9b7a9e646fd8fcdf65e4 349 Gene3D G3DSA:3.60.60.10 86 349 5.7E-30 T 28-03-2018 A21D_RS19195 0a2c9bd663aa9b7a9e646fd8fcdf65e4 349 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 104 312 7.8E-61 T 28-03-2018 IPR005079 Peptidase C45 A21D_RS14270 140c4e778c6e6ebe858299a767afbc0d 280 SUPERFAMILY SSF56281 3 260 3.41E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS14270 140c4e778c6e6ebe858299a767afbc0d 280 Pfam PF00753 Metallo-beta-lactamase superfamily 54 214 1.1E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS14270 140c4e778c6e6ebe858299a767afbc0d 280 SMART SM00849 50 253 5.2E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS14270 140c4e778c6e6ebe858299a767afbc0d 280 Gene3D G3DSA:3.60.15.10 4 268 5.0E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS05810 5da6cea4c4be7dbd15dbfd6a1581b442 305 Pfam PF01032 FecCD transport family 2 299 4.4E-87 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS05810 5da6cea4c4be7dbd15dbfd6a1581b442 305 SUPERFAMILY SSF81345 6 299 2.35E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS05810 5da6cea4c4be7dbd15dbfd6a1581b442 305 Gene3D G3DSA:1.10.3470.10 1 303 7.3E-60 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 Pfam PF00239 Resolvase, N terminal domain 3 133 1.4E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 SUPERFAMILY SSF53041 1 133 1.83E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 SUPERFAMILY SSF46689 139 179 3.85E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 Gene3D G3DSA:3.40.50.1390 1 106 1.5E-31 T 28-03-2018 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 Gene3D G3DSA:1.20.5.40 107 123 1.0E-17 T 28-03-2018 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 Gene3D G3DSA:1.10.10.60 124 182 2.7E-5 T 28-03-2018 A21D_RS13635 48f04d6c2dda1b9b3b0a1ebeb3e97343 186 SMART SM00857 2 136 2.4E-51 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SUPERFAMILY SSF47384 155 232 5.49E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SMART SM00304 119 171 5.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 390 2.8E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SMART SM00387 282 393 3.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SUPERFAMILY SSF55874 244 391 2.49E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 Gene3D G3DSA:3.30.565.10 238 393 3.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 Pfam PF00672 HAMP domain 119 167 2.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 372 3.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 3.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 347 3.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SMART SM00388 172 236 8.5E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 Pfam PF00512 His Kinase A (phospho-acceptor) domain 173 231 1.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 SUPERFAMILY SSF158472 120 167 9.29E-7 T 28-03-2018 A21D_RS08370 d3f594bb52ce99d57f40e09f4179970a 393 Gene3D G3DSA:1.10.287.130 162 231 6.8E-10 T 28-03-2018 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 SUPERFAMILY SSF88659 171 248 2.06E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Pfam PF04542 Sigma-70 region 2 37 104 4.6E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 SUPERFAMILY SSF88946 12 105 1.22E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 247 1.3E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Pfam PF04545 Sigma-70, region 4 198 246 5.9E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Pfam PF04539 Sigma-70 region 3 115 181 1.3E-13 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PRINTS PR00046 Major sigma-70 factor signature 61 74 2.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PRINTS PR00046 Major sigma-70 factor signature 202 214 2.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PRINTS PR00046 Major sigma-70 factor signature 219 234 2.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PRINTS PR00046 Major sigma-70 factor signature 85 93 2.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PRINTS PR00046 Major sigma-70 factor signature 234 245 2.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 248 1.5E-114 T 28-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 SUPERFAMILY SSF88659 109 184 2.35E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Gene3D G3DSA:1.10.601.10 6 105 3.6E-32 T 28-03-2018 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Gene3D G3DSA:1.10.10.10 188 250 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 PIRSF PIRSF000770 11 250 3.5E-36 T 28-03-2018 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 Gene3D G3DSA:1.10.10.10 106 158 1.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 31 247 1.4E-85 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16350 cd89606efd6eeb04f97719140f80e50f 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS16965 c18abfceac1396f046784019da7df09b 220 Pfam PF02517 CAAX protease self-immunity 115 209 7.2E-6 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 Gene3D G3DSA:2.160.10.10 235 290 5.2E-8 T 28-03-2018 A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 Gene3D G3DSA:3.90.550.10 1 234 2.2E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 279 310 1.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 270 298 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 SUPERFAMILY SSF51161 388 432 4.04E-22 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 SUPERFAMILY SSF51161 247 351 4.04E-22 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 Gene3D G3DSA:2.160.10.10 291 447 4.8E-16 T 28-03-2018 A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 SUPERFAMILY SSF53448 269 313 2.39E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS08425 95379f77483ee89f10ab23d0353bee5d 449 SUPERFAMILY SSF53448 1 238 2.39E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS02330 b54641635abf63e9d6c7344843c6e485 102 Gene3D G3DSA:3.40.50.2300 2 101 1.0E-40 T 28-03-2018 A21D_RS02330 b54641635abf63e9d6c7344843c6e485 102 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 88 4.9E-37 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A21D_RS02330 b54641635abf63e9d6c7344843c6e485 102 SUPERFAMILY SSF52794 2 99 1.83E-36 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02330 b54641635abf63e9d6c7344843c6e485 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 8.1E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 ProSitePatterns PS00211 ABC transporters family signature. 389 403 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 Gene3D G3DSA:3.40.50.300 257 461 1.4E-46 T 28-03-2018 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 Gene3D G3DSA:3.40.50.300 1 250 7.5E-56 T 28-03-2018 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 Pfam PF00005 ABC transporter 19 169 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 Pfam PF00005 ABC transporter 279 417 8.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 SUPERFAMILY SSF52540 258 461 1.52E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 SUPERFAMILY SSF52540 2 245 8.68E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 SMART SM00382 287 461 3.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06035 07f4757f70e30984037332ed2586ba87 461 SMART SM00382 27 217 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS02415 2e17ba315af0582a5752662b2b335572 271 Gene3D G3DSA:2.60.120.10 154 270 4.7E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS02415 2e17ba315af0582a5752662b2b335572 271 Gene3D G3DSA:3.10.490.10 2 153 2.3E-9 T 28-03-2018 A21D_RS02415 2e17ba315af0582a5752662b2b335572 271 SUPERFAMILY SSF110857 30 117 1.31E-6 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like A21D_RS02415 2e17ba315af0582a5752662b2b335572 271 SUPERFAMILY SSF51182 168 260 2.94E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS02415 2e17ba315af0582a5752662b2b335572 271 Pfam PF07883 Cupin domain 185 253 6.4E-18 T 28-03-2018 IPR013096 Cupin 2, conserved barrel A21D_RS11505 05a99ad99843d855321405ca067826ed 103 Pfam PF12986 Domain of unknown function (DUF3870) 5 97 4.7E-31 T 28-03-2018 IPR024617 Domain of unknown function DUF3870 A21D_RS10450 24bdffd8732fcc7a4f719d858c498d6f 1537 Gene3D G3DSA:1.20.120.20 9 843 0.047 T 28-03-2018 A21D_RS10450 24bdffd8732fcc7a4f719d858c498d6f 1537 Gene3D G3DSA:1.20.120.20 849 1016 2.1E-11 T 28-03-2018 A21D_RS10450 24bdffd8732fcc7a4f719d858c498d6f 1537 SUPERFAMILY SSF53955 1316 1435 9.57E-12 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS10450 24bdffd8732fcc7a4f719d858c498d6f 1537 Pfam PF01464 Transglycosylase SLT domain 1333 1410 6.7E-12 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A21D_RS10450 24bdffd8732fcc7a4f719d858c498d6f 1537 Gene3D G3DSA:1.10.530.10 1245 1455 3.8E-15 T 28-03-2018 A21D_RS13995 55999512aa4e752ba45a9bcdf0331afd 189 Gene3D G3DSA:2.60.40.200 14 179 1.8E-42 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS13995 55999512aa4e752ba45a9bcdf0331afd 189 SUPERFAMILY SSF49329 26 167 2.62E-40 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS13995 55999512aa4e752ba45a9bcdf0331afd 189 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 32 166 2.6E-38 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:2.60.40.10 1038 1126 1.6E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:2.60.40.10 945 1035 0.007 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:2.60.40.10 1132 1223 2.6E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:3.30.70.80 44 148 2.5E-4 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Pfam PF06280 Fn3-like domain 662 786 2.2E-26 T 28-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 186 197 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A21D_RS04305 5647735886be177ea208feba3a26e081 1265 SUPERFAMILY SSF52025 420 517 4.71E-16 T 28-03-2018 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Pfam PF00082 Subtilase family 181 638 1.6E-56 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Pfam PF02225 PA domain 430 510 6.5E-16 T 28-03-2018 IPR003137 PA domain A21D_RS04305 5647735886be177ea208feba3a26e081 1265 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 578 588 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A21D_RS04305 5647735886be177ea208feba3a26e081 1265 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 256 266 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:3.40.50.200 164 654 2.0E-70 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 SUPERFAMILY SSF52743 537 646 4.19E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 SUPERFAMILY SSF52743 164 395 4.19E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04305 5647735886be177ea208feba3a26e081 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 181 200 6.6E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04305 5647735886be177ea208feba3a26e081 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 577 593 6.6E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04305 5647735886be177ea208feba3a26e081 1265 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 265 6.6E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04305 5647735886be177ea208feba3a26e081 1265 Gene3D G3DSA:2.60.40.1710 655 795 6.3E-28 T 28-03-2018 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 Gene3D G3DSA:2.10.109.10 35 195 5.7E-49 T 28-03-2018 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 89 101 9.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 9.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 148 167 9.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 SUPERFAMILY SSF51306 37 194 2.75E-52 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 Pfam PF00717 Peptidase S24-like 46 113 4.0E-19 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 24 188 1.1E-55 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 ProSitePatterns PS00760 Signal peptidases I lysine active site. 91 103 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A21D_RS18030 f8be12ca8e676156ad84b08de0743c99 196 ProSitePatterns PS00761 Signal peptidases I signature 3. 153 166 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 SUPERFAMILY SSF56634 1 478 2.36E-215 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 329 337 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 SMART SM01060 2 387 8.1E-294 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 Gene3D G3DSA:2.40.180.10 1 353 2.5E-169 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 Pfam PF06628 Catalase-related immune-responsive 409 471 4.5E-25 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 316 342 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 100 117 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 79 97 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 119 137 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 15 38 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PRINTS PR00067 Catalase signature 284 311 2.1E-76 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 ProSitePatterns PS00438 Catalase proximal active site signature. 38 54 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 PIRSF PIRSF038928 1 477 2.4E-225 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS10075 727fc159a213f8d16cdfe4759165c60c 481 Pfam PF00199 Catalase 2 384 2.9E-198 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 SUPERFAMILY SSF101386 226 326 2.45E-23 T 28-03-2018 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 PIRSF PIRSF002845 1 480 1.1E-208 T 28-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 SUPERFAMILY SSF53790 3 252 1.74E-23 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Gene3D G3DSA:3.40.1010.10 2 116 8.4E-14 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Gene3D G3DSA:1.10.287.1080 227 345 4.2E-41 T 28-03-2018 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 250 323 2.7E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 390 446 2.6E-7 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Gene3D G3DSA:1.10.287.1080 359 480 4.5E-25 T 28-03-2018 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 SUPERFAMILY SSF101386 359 456 4.67E-23 T 28-03-2018 A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 TIGRFAM TIGR00444 mazG: MazG family protein 234 477 7.9E-97 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG A21D_RS06720 324f2f7ac86b4e245c76fc583d4c09b3 480 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 203 4.7E-17 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 Pfam PF06018 CodY GAF-like domain 2 178 5.4E-75 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 139.716 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 Gene3D G3DSA:3.30.450.40 1 159 7.0E-29 T 28-03-2018 IPR029016 GAF domain-like A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 3.3E-118 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 Pfam PF08222 CodY helix-turn-helix domain 198 256 1.6E-36 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 PIRSF PIRSF011572 1 257 1.1E-116 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 Gene3D G3DSA:1.10.10.10 160 259 6.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17970 8ae62d3cb233b7688a5586211496a790 259 SUPERFAMILY SSF46785 167 255 1.43E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Gene3D G3DSA:3.40.50.300 36 340 0.024 T 28-03-2018 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Gene3D G3DSA:3.40.50.300 817 974 1.2E-25 T 28-03-2018 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1109 29.49 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Gene3D G3DSA:3.40.50.300 462 793 8.5E-40 T 28-03-2018 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF52540 543 802 1.18E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF52540 377 488 1.42E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Pfam PF00271 Helicase conserved C-terminal domain 827 927 1.5E-16 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF52540 801 1008 3.47E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Pfam PF03461 TRCF domain 1027 1116 1.0E-26 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF143517 1012 1168 1.44E-31 T 28-03-2018 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Pfam PF02559 CarD-like/TRCF domain 499 594 6.6E-31 T 28-03-2018 IPR003711 CarD-like/TRCF domain A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF52540 13 369 1.08E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SMART SM01058 498 595 3.7E-49 T 28-03-2018 IPR003711 CarD-like/TRCF domain A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1097 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SUPERFAMILY SSF141259 489 567 2.09E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 Pfam PF00270 DEAD/DEAH box helicase 625 783 1.6E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SMART SM00982 1024 1120 1.5E-30 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SMART SM00487 619 809 2.0E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS06735 c90ba8467bdbcd64d7613446febb422d 1174 SMART SM00490 845 928 5.5E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS04340 dd90f0f0fe72b74da1826f8ea155bcae 272 Gene3D G3DSA:3.30.930.10 2 263 6.8E-52 T 28-03-2018 A21D_RS04340 dd90f0f0fe72b74da1826f8ea155bcae 272 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 180 3.1E-15 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A21D_RS04340 dd90f0f0fe72b74da1826f8ea155bcae 272 SUPERFAMILY SSF55681 5 262 4.72E-60 T 28-03-2018 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 Pfam PF01380 SIS domain 118 214 1.6E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 69 3.0E-9 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 SUPERFAMILY SSF46689 12 70 6.63E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 Gene3D G3DSA:3.40.50.10490 110 221 6.6E-12 T 28-03-2018 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 SUPERFAMILY SSF53697 100 245 1.21E-17 T 28-03-2018 A21D_RS08925 23617540ec2ec870726ca4a8f4339711 251 Gene3D G3DSA:1.10.10.10 3 109 1.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08090 aa10d595bb67a449e0bac1fcfbc6f3c1 431 Pfam PF00324 Amino acid permease 13 382 4.5E-48 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A21D_RS08090 aa10d595bb67a449e0bac1fcfbc6f3c1 431 PIRSF PIRSF006060 1 426 2.1E-42 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 Pfam PF06574 FAD synthetase 16 169 5.4E-51 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 23 310 1.8E-85 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 Gene3D G3DSA:2.40.30.30 182 318 7.2E-35 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 SMART SM00904 185 311 1.0E-46 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 SUPERFAMILY SSF52374 20 178 1.54E-31 T 28-03-2018 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 PIRSF PIRSF004491 8 318 2.0E-101 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 Gene3D G3DSA:3.40.50.620 12 181 1.3E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 Pfam PF01687 Riboflavin kinase 186 310 4.2E-32 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A21D_RS17710 ebb9248e77cce8c8b185fa3f2e44c339 321 SUPERFAMILY SSF82114 176 314 5.23E-40 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 Gene3D G3DSA:2.60.40.200 47 197 1.5E-43 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 SUPERFAMILY SSF49329 56 196 6.81E-46 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 92 114 5.6E-6 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 171 197 5.6E-6 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 128 137 5.6E-6 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 185 196 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS08905 66b933d9850fd7dd5b3e751e54865bdb 200 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 61 196 9.1E-43 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Gene3D G3DSA:3.40.190.10 1 104 1.5E-42 T 28-03-2018 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Gene3D G3DSA:3.40.190.10 105 198 3.5E-35 T 28-03-2018 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PIRSF PIRSF001438 1 309 3.0E-121 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Gene3D G3DSA:3.30.160.40 219 303 1.3E-20 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 6.0E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 6.0E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 6.0E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 6.0E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 6.0E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 294 39.258 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 212 3.4E-80 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 293 4.2E-113 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 SUPERFAMILY SSF54782 219 307 1.01E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 291 2.0E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15115 0e57384d2dcc62b484d0973e2ee9a6a3 309 SUPERFAMILY SSF53850 2 218 2.71E-80 T 28-03-2018 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 1.3E-53 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 3.4E-31 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 Gene3D G3DSA:3.90.1820.10 1 285 6.3E-51 T 28-03-2018 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 Gene3D G3DSA:3.90.1820.10 286 432 2.5E-28 T 28-03-2018 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 SUPERFAMILY SSF56327 171 427 1.35E-46 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 203 406 9.8E-29 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS12395 e4d4941f70fbb0d095fea9a74bcb7744 432 SUPERFAMILY SSF51735 4 168 3.67E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS05500 cfc1d28618a1af8e7c1741f8c5c541fe 114 Gene3D G3DSA:1.10.260.40 1 114 6.7E-24 T 28-03-2018 A21D_RS05500 cfc1d28618a1af8e7c1741f8c5c541fe 114 Pfam PF01381 Helix-turn-helix 9 61 1.9E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS05500 cfc1d28618a1af8e7c1741f8c5c541fe 114 SMART SM00530 6 61 1.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS05500 cfc1d28618a1af8e7c1741f8c5c541fe 114 SUPERFAMILY SSF47413 2 69 8.31E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 SUPERFAMILY SSF58104 300 568 1.19E-67 T 28-03-2018 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 SUPERFAMILY SSF58104 239 267 1.19E-67 T 28-03-2018 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 Gene3D G3DSA:1.10.287.950 322 569 2.2E-54 T 28-03-2018 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 Gene3D G3DSA:1.10.287.950 156 321 1.1E-9 T 28-03-2018 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 419 6.9E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 13 38 6.9E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 421 450 6.9E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 SMART SM00283 294 569 6.0E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 Pfam PF12729 Four helix bundle sensory module for signal transduction 12 185 8.4E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 522 6.2E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS02895 dd049e0a2da26e87f91612e277800f9a 569 Pfam PF00672 HAMP domain 214 259 3.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS16295 8b7c99b7f87479b4b14647f4eea1ac62 387 SUPERFAMILY SSF89550 5 239 1.65E-11 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS16295 8b7c99b7f87479b4b14647f4eea1ac62 387 Gene3D G3DSA:3.20.20.140 2 249 5.1E-11 T 28-03-2018 A21D_RS16295 8b7c99b7f87479b4b14647f4eea1ac62 387 Gene3D G3DSA:1.10.150.20 317 374 6.3E-7 T 28-03-2018 A21D_RS16295 8b7c99b7f87479b4b14647f4eea1ac62 387 SUPERFAMILY SSF47781 307 370 1.3E-7 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 SUPERFAMILY SSF54373 306 414 1.74E-28 T 28-03-2018 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 Gene3D G3DSA:3.90.660.20 222 414 5.0E-39 T 28-03-2018 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 Gene3D G3DSA:3.90.660.20 55 124 3.7E-6 T 28-03-2018 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 Pfam PF01593 Flavin containing amine oxidoreductase 14 463 9.0E-65 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 Gene3D G3DSA:1.10.3110.10 125 202 5.7E-26 T 28-03-2018 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 4 467 1.5E-97 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 Gene3D G3DSA:3.40.50.20 1 54 0.016 T 28-03-2018 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 SUPERFAMILY SSF51905 432 462 3.56E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13235 0b918ed49490c2ab211b3855cda2cab8 469 SUPERFAMILY SSF51905 5 322 3.56E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 SUPERFAMILY SSF52540 3 220 1.77E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 Pfam PF00005 ABC transporter 268 423 1.1E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 Pfam PF00005 ABC transporter 15 163 2.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 Gene3D G3DSA:3.40.50.300 244 488 3.6E-42 T 28-03-2018 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 SMART SM00382 23 212 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 SUPERFAMILY SSF52540 249 484 7.99E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17630 bbdd01293335d08223519413d8b9b0c9 503 Gene3D G3DSA:3.40.50.300 1 239 9.3E-50 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:3.40.50.10050 508 589 2.7E-29 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:2.40.30.10 611 709 3.1E-30 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 SUPERFAMILY SSF52156 488 617 2.09E-40 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 212 369 2.2E-39 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Pfam PF11987 Translation-initiation factor 2 496 600 8.3E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:2.40.30.10 378 475 3.1E-13 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Pfam PF00009 Elongation factor Tu GTP binding domain 215 371 1.8E-36 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 708 17.408 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 127 707 1.8E-277 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 2.4E-13 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 135 184 1.0E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:3.40.50.300 205 377 1.0E-41 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 SUPERFAMILY SSF52540 204 382 9.93E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 ProSitePatterns PS01176 Initiation factor 2 signature. 661 683 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:3.30.56.50 4 46 2.1E-10 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 Gene3D G3DSA:3.30.56.50 136 177 1.4E-10 T 28-03-2018 A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 SUPERFAMILY SSF50447 611 707 6.24E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS17730 1f5abba516bcd6190ecb40b0aba21a32 709 SUPERFAMILY SSF50447 383 465 8.01E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 Pfam PF02803 Thiolase, C-terminal domain 260 381 3.7E-42 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 1.3E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 Gene3D G3DSA:3.40.47.10 1 254 4.8E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 SUPERFAMILY SSF53901 261 381 2.75E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 PIRSF PIRSF000429 1 383 8.8E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 Gene3D G3DSA:3.40.47.10 255 379 4.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 SUPERFAMILY SSF53901 4 259 8.27E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS12170 765e9c938b38e4cc301953bab1cc8411 383 Pfam PF00108 Thiolase, N-terminal domain 5 252 4.6E-78 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 Pfam PF00733 Asparagine synthase 241 606 7.3E-98 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.5E-46 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 SUPERFAMILY SSF52402 454 579 5.86E-73 T 28-03-2018 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 SUPERFAMILY SSF52402 231 396 5.86E-73 T 28-03-2018 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 SUPERFAMILY SSF56235 2 226 4.37E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 PIRSF PIRSF001589 1 614 4.2E-146 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 Gene3D G3DSA:3.40.50.620 224 614 6.0E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 1.7E-171 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A21D_RS01305 a81380f6e22b042bf11575ed7670028a 615 Gene3D G3DSA:3.60.20.10 1 223 1.2E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS04290 b58eb0345248a5d90a2609387f28ec06 244 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 224 7.0E-39 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS04290 b58eb0345248a5d90a2609387f28ec06 244 SUPERFAMILY SSF51695 6 228 6.02E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS04290 b58eb0345248a5d90a2609387f28ec06 244 Gene3D G3DSA:3.20.20.190 2 241 2.1E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS12415 42b76d35436788b779af9244d21e1a2d 101 Gene3D G3DSA:1.20.58.80 2 100 2.9E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS12415 42b76d35436788b779af9244d21e1a2d 101 SUPERFAMILY SSF46973 2 99 1.31E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS12415 42b76d35436788b779af9244d21e1a2d 101 PIRSF PIRSF000699 1 101 8.7E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS12415 42b76d35436788b779af9244d21e1a2d 101 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 99 9.5E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS14175 caa69699c077b717516648eb0036429c 361 Pfam PF10776 Protein of unknown function (DUF2600) 20 345 2.1E-129 T 28-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 A21D_RS11040 1f26b9d95b605264fa696d60de9a5d31 300 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 294 4.6E-111 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase A21D_RS11040 1f26b9d95b605264fa696d60de9a5d31 300 SUPERFAMILY SSF111331 1 295 1.18E-87 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A21D_RS11040 1f26b9d95b605264fa696d60de9a5d31 300 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 1.1E-36 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A21D_RS11040 1f26b9d95b605264fa696d60de9a5d31 300 SMART SM00046 3 130 7.1E-12 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A21D_RS11040 1f26b9d95b605264fa696d60de9a5d31 300 Gene3D G3DSA:3.40.50.10330 1 134 1.7E-36 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 Pfam PF02421 Ferrous iron transport protein B 3 154 3.7E-59 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 Pfam PF07664 Ferrous iron transport protein B C terminus 459 511 3.5E-18 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 Pfam PF07670 Nucleoside recognition 355 449 9.8E-17 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 Pfam PF07670 Nucleoside recognition 516 640 3.9E-32 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 Gene3D G3DSA:3.40.50.300 3 274 4.6E-24 T 28-03-2018 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 637 6.5E-192 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A21D_RS07710 38351ecd4525ffec780e790da58e90ec 670 SUPERFAMILY SSF52540 5 167 1.45E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 Gene3D G3DSA:3.40.50.1000 77 220 5.5E-28 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 SUPERFAMILY SSF56784 4 215 2.27E-46 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 187 3.7E-32 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 166 5.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 Gene3D G3DSA:1.10.150.240 30 76 6.5E-6 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 187 4.4E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS12030 5f6e0818a83ec9abbb5eedfc050ccf28 221 Gene3D G3DSA:3.40.50.1000 1 29 0.12 T 28-03-2018 IPR023214 HAD-like domain A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 Pfam PF01025 GrpE 43 203 4.2E-52 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 Gene3D G3DSA:2.30.22.10 147 203 5.0E-24 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 SUPERFAMILY SSF51064 149 203 3.66E-19 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 Gene3D G3DSA:3.90.20.20 6 145 1.7E-23 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 SUPERFAMILY SSF58014 54 147 4.84E-26 T 28-03-2018 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 Hamap MF_01151 Protein GrpE [grpE]. 7 203 21.501 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 ProSitePatterns PS01071 grpE protein signature. 158 201 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 PRINTS PR00773 GrpE protein signature 74 90 7.0E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 PRINTS PR00773 GrpE protein signature 155 170 7.0E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 PRINTS PR00773 GrpE protein signature 182 201 7.0E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS15635 b8e9a433f2950eed990a65a70c5ad278 203 PRINTS PR00773 GrpE protein signature 102 117 7.0E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 265 4.5E-79 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 Gene3D G3DSA:3.40.50.720 1 125 3.8E-27 T 28-03-2018 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 PIRSF PIRSF000161 1 265 1.8E-71 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 265 27.549 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 265 3.1E-33 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 Gene3D G3DSA:3.30.360.10 130 234 1.9E-37 T 28-03-2018 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 SUPERFAMILY SSF51735 3 153 1.9E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 SUPERFAMILY SSF55347 129 237 1.18E-39 T 28-03-2018 A21D_RS16705 c0d6e02c71ec50a7cf2e506befbdf2d6 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 128 3.8E-30 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 4.3E-48 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 SUPERFAMILY SSF56327 147 308 6.49E-54 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 3.3E-50 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 3.3E-50 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 3.3E-50 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 3.3E-50 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 3.3E-50 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 PIRSF PIRSF000102 3 309 3.2E-105 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 303 1.6E-123 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 SUPERFAMILY SSF51735 4 146 9.89E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 308 4.0E-30 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 309 44.446 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 Gene3D G3DSA:3.40.50.720 8 147 9.7E-39 T 28-03-2018 A21D_RS04785 bc9f5ba21b00e22c018ddefa83cd91df 310 Gene3D G3DSA:3.90.110.10 148 309 3.7E-48 T 28-03-2018 A21D_RS13350 2d1c8faa860f4a9124a9be30dfd3094a 290 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 9.3E-90 T 28-03-2018 IPR003797 DegV A21D_RS13350 2d1c8faa860f4a9124a9be30dfd3094a 290 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 2.4E-99 T 28-03-2018 IPR003797 DegV A21D_RS13350 2d1c8faa860f4a9124a9be30dfd3094a 290 SUPERFAMILY SSF82549 1 283 1.18E-92 T 28-03-2018 A21D_RS13350 2d1c8faa860f4a9124a9be30dfd3094a 290 Gene3D G3DSA:3.30.1180.10 156 282 5.8E-43 T 28-03-2018 A21D_RS13350 2d1c8faa860f4a9124a9be30dfd3094a 290 Gene3D G3DSA:3.40.50.10170 1 154 6.1E-48 T 28-03-2018 A21D_RS18055 63f703e2b6c7a5e22a1907713e9b99cf 75 Gene3D G3DSA:3.30.300.20 1 75 6.3E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS18055 63f703e2b6c7a5e22a1907713e9b99cf 75 Hamap MF_00088 UPF0109 protein . 1 75 23.861 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 A21D_RS18055 63f703e2b6c7a5e22a1907713e9b99cf 75 Pfam PF13083 KH domain 2 74 1.9E-24 T 28-03-2018 A21D_RS18055 63f703e2b6c7a5e22a1907713e9b99cf 75 SUPERFAMILY SSF54814 15 59 1.37E-7 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Pfam PF00128 Alpha amylase, catalytic domain 29 379 8.1E-134 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 SMART SM00642 14 421 5.8E-167 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Gene3D G3DSA:3.20.20.80 1 119 4.4E-46 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Gene3D G3DSA:2.60.40.1180 483 559 2.4E-21 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 SUPERFAMILY SSF51011 482 558 2.97E-17 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 SUPERFAMILY SSF51445 5 479 9.91E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Gene3D G3DSA:3.20.20.470 172 348 4.4E-41 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Gene3D G3DSA:3.90.400.10 120 171 1.0E-29 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Gene3D G3DSA:3.20.20.80 349 475 2.4E-23 T 28-03-2018 A21D_RS09615 8881bbe1f0b6448a11ce81c0324e3d8a 559 Pfam PF16657 Maltogenic Amylase, C-terminal domain 482 555 2.1E-13 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal A21D_RS06930 f888aafffbeedb7057dd754309ee0aab 171 Gene3D G3DSA:3.40.50.880 1 169 6.9E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS06930 f888aafffbeedb7057dd754309ee0aab 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 170 3.4E-53 T 28-03-2018 IPR006286 Peptidase C56, PfpI A21D_RS06930 f888aafffbeedb7057dd754309ee0aab 171 Pfam PF01965 DJ-1/PfpI family 3 167 1.8E-51 T 28-03-2018 IPR002818 DJ-1/PfpI A21D_RS06930 f888aafffbeedb7057dd754309ee0aab 171 SUPERFAMILY SSF52317 3 169 2.22E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS08050 223429a4bc293959d3f13bc913f6b25e 224 Pfam PF08348 YheO-like PAS domain 7 119 1.8E-29 T 28-03-2018 IPR013559 YheO-like A21D_RS08050 223429a4bc293959d3f13bc913f6b25e 224 Gene3D G3DSA:1.10.10.60 135 216 2.0E-5 T 28-03-2018 A21D_RS08050 223429a4bc293959d3f13bc913f6b25e 224 Pfam PF13309 HTH domain 162 214 7.3E-15 T 28-03-2018 A21D_RS08050 223429a4bc293959d3f13bc913f6b25e 224 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 1 120 1.0E-21 T 28-03-2018 IPR013559 YheO-like A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 Gene3D G3DSA:2.30.30.180 88 154 3.5E-20 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 Pfam PF02576 RimP N-terminal domain 13 84 1.4E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.2E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 SUPERFAMILY SSF74942 85 156 6.15E-21 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 SUPERFAMILY SSF75420 4 84 4.18E-25 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 Gene3D G3DSA:3.30.300.70 1 81 2.8E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A21D_RS17750 c7376d5b2043513ef6cfbf026301c4b3 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.403 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A21D_RS01450 2031831232236565218b25ad80704e93 573 SUPERFAMILY SSF52518 13 198 3.3E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS01450 2031831232236565218b25ad80704e93 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 547 2.8E-54 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS01450 2031831232236565218b25ad80704e93 573 SUPERFAMILY SSF52518 377 571 1.84E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS01450 2031831232236565218b25ad80704e93 573 Gene3D G3DSA:3.40.50.970 360 565 5.3E-54 T 28-03-2018 A21D_RS01450 2031831232236565218b25ad80704e93 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 181 8.9E-53 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS01450 2031831232236565218b25ad80704e93 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 342 1.2E-43 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A21D_RS01450 2031831232236565218b25ad80704e93 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 17 571 1.3E-251 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A21D_RS01450 2031831232236565218b25ad80704e93 573 Gene3D G3DSA:3.40.50.970 9 205 6.7E-57 T 28-03-2018 A21D_RS01450 2031831232236565218b25ad80704e93 573 SUPERFAMILY SSF52467 201 368 1.05E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS01450 2031831232236565218b25ad80704e93 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A21D_RS01450 2031831232236565218b25ad80704e93 573 Gene3D G3DSA:3.40.50.1220 206 359 5.5E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Gene3D G3DSA:3.40.50.300 53 310 1.3E-69 T 28-03-2018 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 SMART SM00382 109 262 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.4E-19 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 53.331 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 406 1.6E-209 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 SUPERFAMILY SSF57716 11 46 2.28E-11 T 28-03-2018 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 SMART SM01086 312 404 4.6E-33 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Gene3D G3DSA:1.10.8.60 312 403 1.2E-33 T 28-03-2018 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 1.0E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 SMART SM00994 10 49 3.0E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 306 4.6E-49 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS15085 758508a14b3034961fc810f588e88c6d 425 SUPERFAMILY SSF52540 59 399 7.04E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00465 75e2d81b94f98b74f75938c8439a1471 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 75 1.4E-19 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A21D_RS00465 75e2d81b94f98b74f75938c8439a1471 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 3.5E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A21D_RS00465 75e2d81b94f98b74f75938c8439a1471 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.5E-8 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A21D_RS00465 75e2d81b94f98b74f75938c8439a1471 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.5E-8 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A21D_RS00465 75e2d81b94f98b74f75938c8439a1471 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.5E-8 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A21D_RS13205 ad5fef2bc15427ddef2c413c8b2a9f59 159 Pfam PF00085 Thioredoxin 63 154 2.9E-13 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS13205 ad5fef2bc15427ddef2c413c8b2a9f59 159 SUPERFAMILY SSF52833 49 154 7.14E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS13205 ad5fef2bc15427ddef2c413c8b2a9f59 159 Gene3D G3DSA:3.40.30.10 26 159 3.2E-20 T 28-03-2018 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 Gene3D G3DSA:2.40.50.100 28 92 1.5E-27 T 28-03-2018 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.2E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.2E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.2E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 SUPERFAMILY SSF110324 10 91 3.49E-31 T 28-03-2018 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.855 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 8.7E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 4.0E-17 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15225 92c3b8dda8c01635eba1867d76af5044 96 Pfam PF01016 Ribosomal L27 protein 10 89 6.5E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS17095 66476ec21f3adf28beb76479bf6f18ae 147 Pfam PF03061 Thioesterase superfamily 18 101 1.2E-13 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS17095 66476ec21f3adf28beb76479bf6f18ae 147 SUPERFAMILY SSF54637 5 133 3.37E-39 T 28-03-2018 IPR029069 HotDog domain A21D_RS17095 66476ec21f3adf28beb76479bf6f18ae 147 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 122 2.9E-32 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A21D_RS17095 66476ec21f3adf28beb76479bf6f18ae 147 Gene3D G3DSA:3.10.129.10 2 143 1.3E-36 T 28-03-2018 A21D_RS17095 66476ec21f3adf28beb76479bf6f18ae 147 PIRSF PIRSF003230 1 136 9.3E-36 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 Gene3D G3DSA:2.30.42.10 198 288 6.5E-18 T 28-03-2018 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 Pfam PF13180 PDZ domain 205 264 2.6E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 419 9.7E-107 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 SMART SM00228 183 257 1.4E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 Pfam PF02163 Peptidase family M50 6 406 7.4E-77 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A21D_RS17760 ddad424cd6ef06cac31ea24d55e97616 420 SUPERFAMILY SSF50156 173 265 4.93E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS12300 eb07cdff45f1d2ed1d73adfe0f73de97 242 SUPERFAMILY SSF53697 2 201 2.83E-28 T 28-03-2018 A21D_RS12300 eb07cdff45f1d2ed1d73adfe0f73de97 242 Gene3D G3DSA:3.40.50.10490 1 239 6.4E-50 T 28-03-2018 A21D_RS12300 eb07cdff45f1d2ed1d73adfe0f73de97 242 Hamap MF_01240 UPF0309 protein . 1 242 42.904 T 28-03-2018 IPR022951 Uncharacterised protein family UPF0309 A21D_RS12300 eb07cdff45f1d2ed1d73adfe0f73de97 242 Pfam PF13580 SIS domain 5 139 1.5E-45 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS05870 eb63fe618c9c1b5f0549f8f5b6912777 258 SMART SM00382 27 217 9.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05870 eb63fe618c9c1b5f0549f8f5b6912777 258 Gene3D G3DSA:3.40.50.300 2 248 1.2E-53 T 28-03-2018 A21D_RS05870 eb63fe618c9c1b5f0549f8f5b6912777 258 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05870 eb63fe618c9c1b5f0549f8f5b6912777 258 Pfam PF00005 ABC transporter 18 167 2.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05870 eb63fe618c9c1b5f0549f8f5b6912777 258 SUPERFAMILY SSF52540 16 230 1.15E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 Gene3D G3DSA:3.40.366.10 169 271 4.5E-21 T 28-03-2018 A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 290 1.3E-14 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 SUPERFAMILY SSF55048 109 177 6.15E-13 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 Pfam PF00698 Acyl transferase domain 1 269 3.8E-27 T 28-03-2018 IPR014043 Acyl transferase A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 SUPERFAMILY SSF52151 178 277 4.19E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 SUPERFAMILY SSF52151 1 110 4.19E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 Gene3D G3DSA:3.40.366.10 1 120 8.2E-23 T 28-03-2018 A21D_RS11920 19044e61c9f845f630a1126e3e9c1d1c 398 Gene3D G3DSA:3.30.70.250 121 168 2.4E-16 T 28-03-2018 A21D_RS11400 6836b215b0bbf32ccae472be6914e634 207 Gene3D G3DSA:3.90.870.10 1 205 7.4E-82 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A21D_RS11400 6836b215b0bbf32ccae472be6914e634 207 SUPERFAMILY SSF55821 2 197 3.43E-76 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A21D_RS11400 6836b215b0bbf32ccae472be6914e634 207 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 195 1.1E-77 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11400 6836b215b0bbf32ccae472be6914e634 207 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 2 195 7.3E-71 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11690 052d553807bcf91f8a3d1f2a9e1c5654 112 SUPERFAMILY SSF101697 3 109 4.97E-38 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 A21D_RS11690 052d553807bcf91f8a3d1f2a9e1c5654 112 Gene3D G3DSA:2.30.30.340 53 109 2.6E-21 T 28-03-2018 A21D_RS11690 052d553807bcf91f8a3d1f2a9e1c5654 112 Gene3D G3DSA:1.10.287.880 3 51 1.7E-19 T 28-03-2018 A21D_RS11690 052d553807bcf91f8a3d1f2a9e1c5654 112 Pfam PF08838 Protein of unknown function (DUF1811) 6 107 1.5E-35 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SUPERFAMILY SSF56281 12 260 6.72E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Gene3D G3DSA:3.40.250.10 357 463 1.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Pfam PF00581 Rhodanese-like domain 277 343 1.6E-5 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Pfam PF00581 Rhodanese-like domain 373 462 3.0E-16 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SUPERFAMILY SSF52821 236 348 2.75E-14 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Pfam PF00753 Metallo-beta-lactamase superfamily 13 161 4.2E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SMART SM00849 12 196 3.7E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SUPERFAMILY SSF52821 367 462 1.14E-27 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SMART SM00450 372 463 1.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 SMART SM00450 268 362 1.4 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Gene3D G3DSA:3.40.250.10 262 356 9.2E-12 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02855 a6b71e55e7b51c74603630fb4a1f8fcb 463 Gene3D G3DSA:3.60.15.10 1 261 1.5E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Gene3D G3DSA:3.40.50.300 468 621 2.2E-22 T 28-03-2018 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Pfam PF13361 UvrD-like helicase C-terminal domain 465 883 3.7E-35 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Gene3D G3DSA:3.90.320.10 1008 1232 5.1E-42 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Gene3D G3DSA:1.10.486.10 622 774 3.2E-40 T 28-03-2018 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 1 1234 19.539 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 SUPERFAMILY SSF52540 337 821 5.93E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 SUPERFAMILY SSF52540 2 144 5.93E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 SUPERFAMILY SSF52540 861 892 5.93E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1056 1225 2.9E-12 T 28-03-2018 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Gene3D G3DSA:3.40.50.300 1 467 1.2E-50 T 28-03-2018 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 SUPERFAMILY SSF52980 1015 1226 1.02E-35 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 455 2.0E-81 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A21D_RS13290 d9b81e8805fd91d8dcce5d87b588d328 1239 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 4 1233 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A21D_RS16570 2e677d29262317fdd2d342a4a0ecdb65 242 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 17 238 2.0E-76 T 28-03-2018 A21D_RS12190 271b6961a17c2dd3600bd50fedc5942a 492 PIRSF PIRSF006060 1 484 5.3E-72 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS12190 271b6961a17c2dd3600bd50fedc5942a 492 Pfam PF13520 Amino acid permease 18 448 3.3E-41 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 4.5E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 130 1.1E-17 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 Gene3D G3DSA:2.60.15.10 1 88 4.6E-26 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.287 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 2.6E-37 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 1.0E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 SUPERFAMILY SSF51344 2 83 4.45E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 Gene3D G3DSA:1.20.5.440 89 131 6.9E-19 T 28-03-2018 A21D_RS04530 9f0f6f2c5edfe99514b6a47cf5c43096 131 SUPERFAMILY SSF46604 87 130 1.41E-10 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SUPERFAMILY SSF55785 218 337 2.09E-15 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Pfam PF02954 Bacterial regulatory protein, Fis family 640 680 1.8E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SUPERFAMILY SSF52540 368 602 3.4E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:1.10.10.60 608 683 1.7E-18 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 121 228 1.9E-8 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 236 350 6.8E-16 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SUPERFAMILY SSF46689 633 682 9.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SMART SM00091 237 302 5.6E-6 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SMART SM00091 117 184 1.1E-5 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:3.40.50.720 1 95 3.1E-11 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Pfam PF13426 PAS domain 128 221 1.4E-7 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Pfam PF00158 Sigma-54 interaction domain 369 536 5.7E-66 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 456 471 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:1.10.8.60 542 607 6.2E-21 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SUPERFAMILY SSF55785 104 220 1.36E-9 T 28-03-2018 IPR000014 PAS domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SMART SM00382 389 533 3.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 583 592 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 94 1.2E-6 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:3.30.450.20 100 225 2.5E-12 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 SUPERFAMILY SSF51735 1 101 1.26E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:3.30.450.20 226 363 1.9E-16 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Gene3D G3DSA:3.40.50.300 364 541 6.1E-27 T 28-03-2018 A21D_RS16170 ac07dfef24fb23bc96f7a7609e8f9d93 688 Pfam PF00989 PAS fold 238 340 2.7E-13 T 28-03-2018 IPR013767 PAS fold GO:0006355 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 12 391 4.2E-108 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 SUPERFAMILY SSF53067 76 121 3.67E-15 T 28-03-2018 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 SUPERFAMILY SSF53067 159 345 3.67E-15 T 28-03-2018 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 SUPERFAMILY SSF53067 12 49 3.67E-15 T 28-03-2018 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 11 392 36.175 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 Gene3D G3DSA:3.30.420.40 10 206 8.9E-60 T 28-03-2018 A21D_RS00990 fff888d8ea3de55abe77b3de19441207 393 Gene3D G3DSA:3.30.420.40 254 393 3.6E-17 T 28-03-2018 A21D_RS01520 75fbf9a76e679918cad40513322694f2 127 SUPERFAMILY SSF51182 33 106 2.02E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS01520 75fbf9a76e679918cad40513322694f2 127 Gene3D G3DSA:2.60.120.10 2 109 6.2E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS01800 930f62a0ee252e9311fcafba5ffa07fb 204 Pfam PF08000 Bacterial PH domain 10 132 7.3E-34 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain A21D_RS01800 930f62a0ee252e9311fcafba5ffa07fb 204 SUPERFAMILY SSF50729 14 203 1.17E-59 T 28-03-2018 IPR011993 PH domain-like A21D_RS01800 930f62a0ee252e9311fcafba5ffa07fb 204 Gene3D G3DSA:2.30.29.50 21 112 8.1E-28 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain A21D_RS01800 930f62a0ee252e9311fcafba5ffa07fb 204 Gene3D G3DSA:1.10.287.210 116 204 5.3E-27 T 28-03-2018 A21D_RS01800 930f62a0ee252e9311fcafba5ffa07fb 204 Pfam PF11724 YvbH-like oligomerisation region 145 204 2.1E-19 T 28-03-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 SUPERFAMILY SSF52540 328 573 4.31E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 Pfam PF00005 ABC transporter 354 501 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 SMART SM00382 363 549 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 Gene3D G3DSA:1.20.1560.10 2 323 1.6E-55 T 28-03-2018 A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 SUPERFAMILY SSF90123 6 319 7.98E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 Pfam PF00664 ABC transporter transmembrane region 21 292 5.6E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS12870 7ca99851e33edbab301f198a170a8d36 582 Gene3D G3DSA:3.40.50.300 324 579 7.4E-74 T 28-03-2018 A21D_RS16050 85a84e635a2984481b811e65ded8a65c 309 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 283 1.4E-111 T 28-03-2018 IPR014217 Sporulation stage III, protein AA A21D_RS16050 85a84e635a2984481b811e65ded8a65c 309 SMART SM00382 136 278 0.0064 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS16050 85a84e635a2984481b811e65ded8a65c 309 Gene3D G3DSA:3.40.50.300 45 285 1.6E-8 T 28-03-2018 A21D_RS16050 85a84e635a2984481b811e65ded8a65c 309 SUPERFAMILY SSF52540 12 261 2.49E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 PIRSF PIRSF000505 3 429 9.7E-122 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 Gene3D G3DSA:3.65.10.10 220 428 3.8E-55 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 423 2.5E-121 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 SUPERFAMILY SSF55205 10 427 5.78E-133 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 427 3.2E-129 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 32.992 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A21D_RS16640 4527ddc9e3cca961ffc3650ba703061e 429 Gene3D G3DSA:3.65.10.10 22 219 1.2E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04020 0e94fd345116b2216c8bd6359c4761cf 256 Gene3D G3DSA:2.20.28.20 2 27 3.6E-7 T 28-03-2018 A21D_RS04020 0e94fd345116b2216c8bd6359c4761cf 256 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 239 4.0E-8 T 28-03-2018 A21D_RS08965 070bada20dfce0275f55c6228f18cd97 409 SUPERFAMILY SSF53098 63 342 3.87E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS08965 070bada20dfce0275f55c6228f18cd97 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.7E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS08965 070bada20dfce0275f55c6228f18cd97 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS08965 070bada20dfce0275f55c6228f18cd97 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS07375 070bada20dfce0275f55c6228f18cd97 409 SUPERFAMILY SSF53098 63 342 3.87E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS07375 070bada20dfce0275f55c6228f18cd97 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.7E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS07375 070bada20dfce0275f55c6228f18cd97 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS07375 070bada20dfce0275f55c6228f18cd97 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 SUPERFAMILY SSF55129 3 60 5.49E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 PIRSF PIRSF002211 1 60 3.8E-26 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 20.069 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 2.9E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 8.8E-25 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06285 6db5a758642e4469e710ac4b4e0c68be 60 Gene3D G3DSA:3.30.1390.20 5 59 8.9E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A21D_RS12515 2583740d3ced27688bfa821c3d78a50c 232 Pfam PF00571 CBS domain 180 230 4.9E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS12515 2583740d3ced27688bfa821c3d78a50c 232 SUPERFAMILY SSF54631 103 230 2.06E-9 T 28-03-2018 A21D_RS12515 2583740d3ced27688bfa821c3d78a50c 232 Gene3D G3DSA:3.10.580.10 95 232 7.4E-13 T 28-03-2018 A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 Gene3D G3DSA:3.30.1340.20 76 176 9.2E-38 T 28-03-2018 IPR004173 3H domain GO:0036094 A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 Pfam PF08279 HTH domain 12 64 3.6E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 SUPERFAMILY SSF46785 8 66 9.21E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 SUPERFAMILY SSF75500 74 177 3.01E-34 T 28-03-2018 IPR004173 3H domain GO:0036094 A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 83 176 1.0E-28 T 28-03-2018 IPR004173 3H domain GO:0036094 A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 Gene3D G3DSA:1.10.10.10 1 69 4.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 PIRSF PIRSF037847 7 178 5.8E-65 T 28-03-2018 IPR026043 Transcription repressor NadR A21D_RS03440 2aba7577bc6e8576a4323020a5b8afd6 183 Pfam PF02829 3H domain 79 175 2.4E-34 T 28-03-2018 IPR004173 3H domain GO:0036094 A21D_RS15255 ea12d157f14a36780b251ab9304c68cf 185 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 183 9.2E-17 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A21D_RS13180 0b846c22d178a28a9d0803e7ff82e154 410 Pfam PF05977 Transmembrane secretion effector 12 401 6.5E-37 T 28-03-2018 IPR010290 Transmembrane secretion effector A21D_RS13180 0b846c22d178a28a9d0803e7ff82e154 410 Gene3D G3DSA:1.20.1250.20 204 406 2.4E-14 T 28-03-2018 A21D_RS13180 0b846c22d178a28a9d0803e7ff82e154 410 SUPERFAMILY SSF103473 15 404 7.19E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS13180 0b846c22d178a28a9d0803e7ff82e154 410 Gene3D G3DSA:1.20.1250.20 7 203 4.3E-26 T 28-03-2018 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 Gene3D G3DSA:3.40.1080.10 1 279 2.0E-78 T 28-03-2018 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 SMART SM00882 15 254 3.6E-60 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 Pfam PF01144 Coenzyme A transferase 16 253 1.1E-36 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 PIRSF PIRSF000858 10 535 5.8E-219 T 28-03-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 Gene3D G3DSA:3.40.1080.10 286 535 3.7E-58 T 28-03-2018 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 SUPERFAMILY SSF100950 287 528 5.39E-74 T 28-03-2018 A21D_RS09230 379371ecc083aa73948d23e1d9daf122 544 SUPERFAMILY SSF100950 14 265 1.17E-84 T 28-03-2018 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 SUPERFAMILY SSF52172 1 183 3.47E-28 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 Pfam PF00072 Response regulator receiver domain 1 109 2.8E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 207 3.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 SMART SM00448 1 111 1.5E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 Gene3D G3DSA:1.10.10.10 120 216 5.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 Gene3D G3DSA:3.40.50.2300 1 119 1.1E-27 T 28-03-2018 A21D_RS02665 3b85169db704db2d707c0898913c3a79 229 SMART SM00421 152 209 6.9E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS03585 f820a175f431962f52a7ef942d667ca2 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 4.8E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS03585 f820a175f431962f52a7ef942d667ca2 409 Pfam PF01609 Transposase DDE domain 126 329 2.2E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS03585 f820a175f431962f52a7ef942d667ca2 409 Gene3D G3DSA:3.90.350.10 123 310 9.0E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS03585 f820a175f431962f52a7ef942d667ca2 409 SUPERFAMILY SSF53098 63 342 8.34E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS13295 50efcfc24fa27628a46b206774d4f608 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 2.2E-29 T 28-03-2018 IPR019618 Spore germination protein GerPA/GerPF A21D_RS01335 41de91eee43dd1fd2d24c618f22f2cff 522 SUPERFAMILY SSF53474 68 287 7.07E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS01335 41de91eee43dd1fd2d24c618f22f2cff 522 Gene3D G3DSA:3.40.50.1820 69 225 1.0E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS01335 41de91eee43dd1fd2d24c618f22f2cff 522 Gene3D G3DSA:3.40.50.1820 226 345 0.051 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS01335 41de91eee43dd1fd2d24c618f22f2cff 522 Gene3D G3DSA:2.60.40.10 349 515 4.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS13300 768d0e0dc2a266ca873eab0f728c896a 127 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 6 125 5.0E-12 T 28-03-2018 IPR024496 Spore germination protein GerPE A21D_RS13300 768d0e0dc2a266ca873eab0f728c896a 127 Pfam PF10970 Spore germination protein GerPE 5 121 1.2E-25 T 28-03-2018 IPR024496 Spore germination protein GerPE A21D_RS03410 2310000f50e389b1c8a2b6f7ea0ed558 167 Gene3D G3DSA:1.20.1260.10 1 161 1.2E-33 T 28-03-2018 IPR012347 Ferritin-related A21D_RS03410 2310000f50e389b1c8a2b6f7ea0ed558 167 Pfam PF00210 Ferritin-like domain 8 140 2.3E-29 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A21D_RS03410 2310000f50e389b1c8a2b6f7ea0ed558 167 SUPERFAMILY SSF47240 1 160 3.51E-40 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS19550 7c2042820875b1b6bf73244565522c7d 155 Pfam PF00583 Acetyltransferase (GNAT) family 48 135 2.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS19550 7c2042820875b1b6bf73244565522c7d 155 SUPERFAMILY SSF55729 28 143 1.26E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS19550 7c2042820875b1b6bf73244565522c7d 155 Gene3D G3DSA:3.40.630.30 7 153 7.6E-17 T 28-03-2018 A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 Pfam PF11967 Recombination protein O N terminal 4 78 2.8E-26 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 29.052 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 Pfam PF02565 Recombination protein O C terminal 82 237 2.9E-36 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 Gene3D G3DSA:2.40.50.140 1 81 1.5E-24 T 28-03-2018 A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 SUPERFAMILY SSF57863 80 231 8.11E-38 T 28-03-2018 A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 SUPERFAMILY SSF50249 3 78 1.44E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS15735 be1466bf75650b9d3f6d2cf09cb5ab38 247 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 6.2E-76 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A21D_RS14400 b996a05383a511ecd6c34de104e6ba88 168 SUPERFAMILY SSF55781 11 160 2.4E-43 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14400 b996a05383a511ecd6c34de104e6ba88 168 Pfam PF13185 GAF domain 52 157 6.3E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 A21D_RS14400 b996a05383a511ecd6c34de104e6ba88 168 Gene3D G3DSA:3.30.450.40 9 167 1.1E-23 T 28-03-2018 IPR029016 GAF domain-like A21D_RS14400 b996a05383a511ecd6c34de104e6ba88 168 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 100 117 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site A21D_RS14400 b996a05383a511ecd6c34de104e6ba88 168 SMART SM00065 31 164 0.0015 T 28-03-2018 IPR003018 GAF domain GO:0005515 A21D_RS00725 4e55a5e1838df6a4c299eabfe45690dd 219 SUPERFAMILY SSF102588 3 186 4.97E-47 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A21D_RS00725 4e55a5e1838df6a4c299eabfe45690dd 219 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 218 6.4E-98 T 28-03-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 A21D_RS00725 4e55a5e1838df6a4c299eabfe45690dd 219 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 134 7.8E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A21D_RS00725 4e55a5e1838df6a4c299eabfe45690dd 219 Gene3D G3DSA:3.40.50.10320 2 217 1.5E-43 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 214 419 9.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 Gene3D G3DSA:1.20.58.370 20 165 8.2E-9 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 SUPERFAMILY SSF161098 180 417 9.16E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 SUPERFAMILY SSF160964 83 98 5.36E-9 T 28-03-2018 A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 SUPERFAMILY SSF160964 128 185 5.36E-9 T 28-03-2018 A21D_RS01105 e79668057cd9089967d28246a9d9899e 432 Gene3D G3DSA:1.10.3720.10 189 423 7.8E-47 T 28-03-2018 A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 TIGRFAM TIGR02336 TIGR02336: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase 4 718 0.0 T 28-03-2018 IPR012711 Lacto-N-biose phosphorylase/D-galactosyl-beta-1->4-L-rhamnose phosphorylase GO:0004645 A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Pfam PF09508 Lacto-N-biose phosphorylase N-terminal TIM barrel domain 6 438 5.7E-218 T 28-03-2018 IPR035080 Lacto-N-biose phosphorylase-like, N-terminal TIM barrel domain A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Gene3D G3DSA:3.40.50.880 438 592 3.8E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Gene3D G3DSA:3.40.50.880 593 662 3.0E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Gene3D G3DSA:2.60.40.1180 665 718 2.1E-23 T 28-03-2018 A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Pfam PF17386 Lacto-N-biose phosphorylase C-terminal domain 665 716 1.7E-22 T 28-03-2018 IPR035356 Lacto-N-biose phosphorylase, C-terminal domain A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Pfam PF17385 Lacto-N-biose phosphorylase central domain 441 660 2.3E-95 T 28-03-2018 IPR035363 Lacto-N-biose phosphorylase, central domain A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 SUPERFAMILY SSF52317 444 657 1.25E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Gene3D G3DSA:3.20.20.80 138 433 5.8E-150 T 28-03-2018 A21D_RS01370 294cc32c66cd561ed1ef6a4ca1a7bdd0 720 Gene3D G3DSA:3.20.20.80 24 137 1.8E-29 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 Gene3D G3DSA:1.10.3370.10 1 430 1.2E-157 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PIRSF PIRSF004557 1 430 4.6E-128 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.436 T 28-03-2018 IPR026593 Protein translocase subunit SecY A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 8.3E-145 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 6.1E-99 T 28-03-2018 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 SUPERFAMILY SSF103491 1 420 2.09E-128 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS06275 0016acfb6ba9adbde62cef409a866fe7 430 Pfam PF00344 SecY translocase 68 413 6.8E-115 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A21D_RS01050 fb46a3523e11e3ca646c7925bb6a3b52 323 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 266 1.6E-32 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A21D_RS01050 fb46a3523e11e3ca646c7925bb6a3b52 323 SUPERFAMILY SSF53067 116 317 7.87E-44 T 28-03-2018 A21D_RS01050 fb46a3523e11e3ca646c7925bb6a3b52 323 Gene3D G3DSA:3.30.420.40 4 104 3.6E-16 T 28-03-2018 A21D_RS01050 fb46a3523e11e3ca646c7925bb6a3b52 323 SUPERFAMILY SSF53067 1 113 1.3E-15 T 28-03-2018 A21D_RS01050 fb46a3523e11e3ca646c7925bb6a3b52 323 Gene3D G3DSA:3.30.420.40 117 280 1.3E-42 T 28-03-2018 A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 149 1.3E-85 T 28-03-2018 IPR013404 Competence operon E, ComEB A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 SUPERFAMILY SSF53927 7 140 1.64E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 PIRSF PIRSF006019 1 151 8.7E-59 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 Gene3D G3DSA:3.40.140.10 3 149 7.1E-39 T 28-03-2018 A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 9.5E-27 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A21D_RS15580 977be1f58cb92bb496584d37074923e9 192 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A21D_RS03080 8e5ff6415ff3f6da8615a6ed95019f16 316 Pfam PF01032 FecCD transport family 32 311 4.1E-48 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS03080 8e5ff6415ff3f6da8615a6ed95019f16 316 SUPERFAMILY SSF81345 9 311 4.97E-56 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS03080 8e5ff6415ff3f6da8615a6ed95019f16 316 Gene3D G3DSA:1.10.3470.10 6 316 5.9E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 Pfam PF00202 Aminotransferase class-III 16 396 2.5E-132 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 SUPERFAMILY SSF53383 1 396 1.5E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 396 5.8E-167 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 Hamap MF_01689 Ornithine aminotransferase [rocD]. 5 397 66.207 T 28-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 Gene3D G3DSA:3.90.1150.10 1 168 3.4E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 Gene3D G3DSA:3.40.640.10 170 294 5.6E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 PIRSF PIRSF000521 175 398 4.6E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 PIRSF PIRSF000521 1 160 1.2E-9 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS13330 67efc8f8947d37aa8eee5e5b8bde927f 398 Gene3D G3DSA:3.90.1150.10 295 398 2.2E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS02090 6c2c21a7674a668c8db42bcd3acab729 429 Pfam PF02371 Transposase IS116/IS110/IS902 family 292 373 6.6E-20 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A21D_RS02090 6c2c21a7674a668c8db42bcd3acab729 429 Pfam PF01548 Transposase 19 179 2.1E-33 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A21D_RS05445 6c2c21a7674a668c8db42bcd3acab729 429 Pfam PF02371 Transposase IS116/IS110/IS902 family 292 373 6.6E-20 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A21D_RS05445 6c2c21a7674a668c8db42bcd3acab729 429 Pfam PF01548 Transposase 19 179 2.1E-33 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A21D_RS14440 16d14ddf5b3191b019fe741e6552db72 151 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 126 6.0E-53 T 28-03-2018 IPR014229 Sporulation protein YtfJ A21D_RS14440 16d14ddf5b3191b019fe741e6552db72 151 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 119 5.8E-29 T 28-03-2018 IPR014229 Sporulation protein YtfJ A21D_RS14440 16d14ddf5b3191b019fe741e6552db72 151 PIRSF PIRSF021377 1 150 9.0E-60 T 28-03-2018 IPR014229 Sporulation protein YtfJ A21D_RS00835 74908c5fbf6c73794aa98355a4b972d9 73 Hamap MF_00167 Carbon storage regulator [csrA]. 1 67 20.145 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS00835 74908c5fbf6c73794aa98355a4b972d9 73 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-15 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS00835 74908c5fbf6c73794aa98355a4b972d9 73 SUPERFAMILY SSF117130 1 55 3.27E-19 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS00835 74908c5fbf6c73794aa98355a4b972d9 73 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 61 3.4E-27 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS00835 74908c5fbf6c73794aa98355a4b972d9 73 Pfam PF02599 Global regulator protein family 1 52 3.0E-25 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A21D_RS04255 11ce014d6c85736da394231133e8697e 879 Pfam PF00535 Glycosyl transferase family 2 552 694 1.1E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A21D_RS04255 11ce014d6c85736da394231133e8697e 879 SUPERFAMILY SSF53448 551 785 6.66E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS04255 11ce014d6c85736da394231133e8697e 879 Gene3D G3DSA:3.90.550.10 546 826 2.3E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 SMART SM00342 193 276 2.7E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 SUPERFAMILY SSF51215 12 161 7.06E-22 T 28-03-2018 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 Gene3D G3DSA:1.10.10.60 156 226 1.2E-13 T 28-03-2018 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 SUPERFAMILY SSF46689 229 279 8.51E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 Pfam PF12833 Helix-turn-helix domain 199 277 2.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 Gene3D G3DSA:2.60.120.10 8 115 1.2E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 SUPERFAMILY SSF46689 176 226 1.79E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 Gene3D G3DSA:1.10.10.60 227 281 9.8E-13 T 28-03-2018 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 6.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 6.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 Pfam PF02311 AraC-like ligand binding domain 20 140 4.0E-17 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A21D_RS03710 be5056202247dbfa7b59779f9e7dd01d 281 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 230 272 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS07995 5bf56af84f3a85c58850fd2b4686c145 217 SUPERFAMILY SSF161098 14 200 7.3E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07995 5bf56af84f3a85c58850fd2b4686c145 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 205 7.7E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07995 5bf56af84f3a85c58850fd2b4686c145 217 Gene3D G3DSA:1.10.3720.10 2 210 3.6E-30 T 28-03-2018 A21D_RS07295 3340c7088529bbfe7cc4ce61d578114d 200 Pfam PF06866 Protein of unknown function (DUF1256) 16 177 1.2E-60 T 28-03-2018 IPR009665 Protein of unknown function DUF1256 A21D_RS07295 3340c7088529bbfe7cc4ce61d578114d 200 Gene3D G3DSA:3.40.50.1450 10 197 3.5E-30 T 28-03-2018 IPR023430 Peptidase HybD-like domain A21D_RS07295 3340c7088529bbfe7cc4ce61d578114d 200 SUPERFAMILY SSF53163 12 189 5.89E-46 T 28-03-2018 IPR023430 Peptidase HybD-like domain A21D_RS07295 3340c7088529bbfe7cc4ce61d578114d 200 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 40 177 7.3E-63 T 28-03-2018 IPR009665 Protein of unknown function DUF1256 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 Gene3D G3DSA:3.40.190.10 88 175 1.7E-11 T 28-03-2018 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 Pfam PF03466 LysR substrate binding domain 87 290 1.5E-34 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 SUPERFAMILY SSF53850 87 290 1.09E-31 T 28-03-2018 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 Gene3D G3DSA:1.10.10.10 1 83 3.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 Gene3D G3DSA:3.40.190.10 176 268 1.5E-14 T 28-03-2018 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.7E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS19405 c78c1acb92fd84ec2356219d2b3927a9 294 SUPERFAMILY SSF46785 1 84 1.05E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 Gene3D G3DSA:2.60.120.10 10 164 1.6E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 162 203 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 SUPERFAMILY SSF46689 107 159 8.51E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 SMART SM00342 125 207 8.2E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 SUPERFAMILY SSF46689 161 211 5.82E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 Pfam PF12833 Helix-turn-helix domain 132 208 2.8E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 Gene3D G3DSA:1.10.10.60 165 215 7.5E-13 T 28-03-2018 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 191 207 5.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS02445 014cada926c63b6a98a8a8afa94de66d 224 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 176 191 5.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS05595 9c5ea47399411bab80bd77ad88114b4e 265 SUPERFAMILY SSF56973 4 243 3.92E-38 T 28-03-2018 A21D_RS05595 9c5ea47399411bab80bd77ad88114b4e 265 Gene3D G3DSA:2.170.15.10 49 245 1.7E-31 T 28-03-2018 A21D_RS05595 9c5ea47399411bab80bd77ad88114b4e 265 Pfam PF03318 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 47 247 8.8E-49 T 28-03-2018 IPR004991 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 A21D_RS03745 65cb507fa0db4c55110e93549a41d751 186 Gene3D G3DSA:3.90.1720.10 8 184 1.5E-11 T 28-03-2018 A21D_RS03745 65cb507fa0db4c55110e93549a41d751 186 SUPERFAMILY SSF54001 8 166 1.28E-9 T 28-03-2018 A21D_RS12490 3f06c0ebef1a8d7951cee5e9972b89f0 233 Gene3D G3DSA:3.40.630.30 7 184 2.9E-7 T 28-03-2018 A21D_RS12490 3f06c0ebef1a8d7951cee5e9972b89f0 233 SUPERFAMILY SSF55729 20 156 8.34E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS02360 dd20bb41708e960abd5684f9f82e0543 181 PIRSF PIRSF038321 1 181 2.1E-89 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 A21D_RS02360 dd20bb41708e960abd5684f9f82e0543 181 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 6 170 3.2E-76 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 A21D_RS02360 dd20bb41708e960abd5684f9f82e0543 181 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 179 5.1E-83 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 Gene3D G3DSA:3.40.1160.10 1 240 1.5E-44 T 28-03-2018 A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 SUPERFAMILY SSF53633 5 238 1.83E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 3.3E-101 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.477 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 Pfam PF00696 Amino acid kinase family 8 217 1.3E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS17780 33bf224528fe9c9588cfb6bdcd3c3549 240 PIRSF PIRSF005650 1 240 5.9E-97 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 SUPERFAMILY SSF51556 60 365 4.99E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 SUPERFAMILY SSF51338 369 408 3.78E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 SUPERFAMILY SSF51338 5 60 3.78E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 Gene3D G3DSA:3.20.20.140 70 368 1.5E-48 T 28-03-2018 A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 Pfam PF01979 Amidohydrolase family 56 408 9.5E-56 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS19285 e6a7f72f28a5dd7735407280d36cc62a 419 Gene3D G3DSA:2.30.40.10 1 69 3.4E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 SUPERFAMILY SSF51971 151 422 1.77E-54 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 477 2.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Gene3D G3DSA:3.50.50.60 423 495 1.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Gene3D G3DSA:1.10.1060.10 2 150 8.1E-34 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 138 8.9E-17 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Gene3D G3DSA:3.50.50.60 364 422 2.7E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Gene3D G3DSA:3.50.50.60 250 334 2.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 1.4E-22 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 1.4E-22 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 1.4E-22 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 1.4E-22 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 Gene3D G3DSA:3.40.50.720 151 249 7.7E-18 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 SUPERFAMILY SSF46548 2 163 2.56E-31 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 SUPERFAMILY SSF51971 406 491 7.42E-11 T 28-03-2018 A21D_RS08765 3534b6ee0fbec30bbe1f6840996181a3 495 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 495 2.6E-217 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 131 3.5E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 Pfam PF00117 Glutamine amidotransferase class-I 175 351 7.0E-47 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00097 Anthranilate synthase component II signature 328 341 2.7E-7 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.7E-7 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.7E-7 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 Gene3D G3DSA:3.40.50.880 143 358 1.2E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 4.6E-12 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 328 341 4.6E-12 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 4.6E-12 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 SMART SM01097 2 132 3.9E-86 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 SUPERFAMILY SSF52317 144 355 1.3E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 357 46.749 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 1.7E-36 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 1.7E-36 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 1.7E-36 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 1.7E-36 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 1.7E-36 T 28-03-2018 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 354 3.5E-144 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 Gene3D G3DSA:3.50.30.20 1 142 9.8E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS18285 d14685cc1693e3e2f5445c8c5d3011b9 364 SUPERFAMILY SSF52021 3 143 3.27E-56 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A21D_RS06625 bbe49e52bf1555cb78b4962cb6144c9d 172 Gene3D G3DSA:3.30.70.560 1 171 2.1E-61 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A21D_RS06625 bbe49e52bf1555cb78b4962cb6144c9d 172 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 4.4E-39 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A21D_RS06625 bbe49e52bf1555cb78b4962cb6144c9d 172 SUPERFAMILY SSF55083 1 141 3.27E-54 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A21D_RS06625 bbe49e52bf1555cb78b4962cb6144c9d 172 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 1.6E-47 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A21D_RS06625 bbe49e52bf1555cb78b4962cb6144c9d 172 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 Gene3D G3DSA:3.90.76.10 56 208 2.4E-40 T 28-03-2018 A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 450 9.8E-106 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 Gene3D G3DSA:3.10.105.10 303 505 4.3E-65 T 28-03-2018 A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 Gene3D G3DSA:3.40.190.10 209 302 4.3E-31 T 28-03-2018 A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 PIRSF PIRSF002741 1 534 7.0E-133 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS10650 3a80c4707f62e23e6b02dad8749e2556 534 SUPERFAMILY SSF53850 44 533 2.02E-151 T 28-03-2018 A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 SMART SM00116 78 125 6.1E-6 T 28-03-2018 IPR000644 CBS domain A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 SMART SM00116 12 60 5.9E-13 T 28-03-2018 IPR000644 CBS domain A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 Pfam PF00571 CBS domain 6 56 7.2E-14 T 28-03-2018 IPR000644 CBS domain A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 Pfam PF00571 CBS domain 70 121 2.1E-9 T 28-03-2018 IPR000644 CBS domain A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 Gene3D G3DSA:3.10.580.10 68 142 1.7E-12 T 28-03-2018 A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 Gene3D G3DSA:3.10.580.10 1 67 2.4E-18 T 28-03-2018 A21D_RS00410 4c1cb67d02d68ff174c6cad9e74e0949 145 SUPERFAMILY SSF54631 4 120 7.96E-34 T 28-03-2018 A21D_RS09065 86a0cd5109af9a6d83d9a6de631e4b1b 315 Gene3D G3DSA:3.40.50.720 1 315 1.3E-33 T 28-03-2018 A21D_RS09065 86a0cd5109af9a6d83d9a6de631e4b1b 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 239 4.3E-25 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A21D_RS09065 86a0cd5109af9a6d83d9a6de631e4b1b 315 SUPERFAMILY SSF51735 1 312 8.01E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS00400 8f0958eefbe483f447484001e17df877 192 Pfam PF08876 Domain of unknown function (DUF1836) 19 122 8.6E-32 T 28-03-2018 IPR014975 Protein of unknown function DUF1836 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Pfam PF02222 ATP-grasp domain 117 286 4.8E-52 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 SUPERFAMILY SSF51246 310 372 5.18E-14 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Gene3D G3DSA:3.40.50.20 10 96 6.8E-26 T 28-03-2018 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 12 361 40.375 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 12 366 1.1E-114 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Gene3D G3DSA:3.30.1490.20 123 187 8.6E-14 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 77 2.1E-4 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 Gene3D G3DSA:3.30.470.20 188 375 3.3E-35 T 28-03-2018 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 SUPERFAMILY SSF56059 108 303 6.36E-59 T 28-03-2018 A21D_RS10925 426d7b21a4ad3471f1416f99b96042a2 375 SUPERFAMILY SSF52440 10 104 5.47E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS03525 5c7dfa58686f5a5374616c24f03a502b 300 SUPERFAMILY SSF52540 2 221 2.66E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03525 5c7dfa58686f5a5374616c24f03a502b 300 Pfam PF00005 ABC transporter 17 159 1.4E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03525 5c7dfa58686f5a5374616c24f03a502b 300 Gene3D G3DSA:3.40.50.300 1 260 1.1E-53 T 28-03-2018 A21D_RS03525 5c7dfa58686f5a5374616c24f03a502b 300 SMART SM00382 26 208 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08705 b8a0b3b5aec14225ae2357c81c6aeb6e 155 SUPERFAMILY SSF54637 5 148 1.17E-24 T 28-03-2018 IPR029069 HotDog domain A21D_RS08705 b8a0b3b5aec14225ae2357c81c6aeb6e 155 Pfam PF03061 Thioesterase superfamily 54 136 4.1E-5 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS08705 b8a0b3b5aec14225ae2357c81c6aeb6e 155 Gene3D G3DSA:3.10.129.10 1 153 1.5E-23 T 28-03-2018 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Gene3D G3DSA:3.30.230.10 222 394 9.7E-55 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 SMART SM00387 33 177 1.1E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 182 197 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 197 210 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 474 483 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 609 625 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 312 328 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 593 605 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 221 243 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 362 376 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 8 18 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR01159 DNA gyrase subunit B signature 376 396 6.7E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 1.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 SUPERFAMILY SSF54211 222 392 3.6E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Gene3D G3DSA:3.40.50.670 403 635 1.2E-92 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 SMART SM00433 37 633 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 SUPERFAMILY SSF56719 398 633 2.62E-85 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 629 2.0E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 638 47.832 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Pfam PF00204 DNA gyrase B 222 392 9.0E-56 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 5 642 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 114 128 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 572 588 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 268 281 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 490 506 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 424 438 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 508 525 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 PRINTS PR00418 DNA topoisomerase II family signature 528 540 1.9E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Gene3D G3DSA:3.30.565.10 20 221 2.3E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 SUPERFAMILY SSF55874 8 217 5.89E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS17050 225f30f48a56961388b32eb1fa5dc9ed 652 Pfam PF01751 Toprim domain 423 532 3.8E-18 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 2.9E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 565 1.7E-242 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Gene3D G3DSA:1.10.274.10 25 136 8.4E-37 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 SUPERFAMILY SSF51621 249 546 4.45E-110 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Gene3D G3DSA:3.50.30.10 137 254 7.5E-33 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 7.9E-32 T 28-03-2018 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 7.9E-32 T 28-03-2018 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 7.9E-32 T 28-03-2018 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 7.9E-32 T 28-03-2018 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 SUPERFAMILY SSF52009 125 247 3.27E-38 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 6.6E-126 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 SUPERFAMILY SSF47831 24 143 1.7E-35 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 4.0E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 PIRSF PIRSF000732 1 570 1.1E-222 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 Gene3D G3DSA:3.20.20.60 255 570 1.9E-100 T 28-03-2018 A21D_RS00475 8c549ea41125fb5704edd78b467abb91 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A21D_RS14640 b21f8483a9a40cf751f002e6bb3b599e 444 Gene3D G3DSA:1.10.10.630 304 375 3.9E-11 T 28-03-2018 IPR034829 DnaD-like domain A21D_RS14640 b21f8483a9a40cf751f002e6bb3b599e 444 Pfam PF07261 Replication initiation and membrane attachment 314 376 5.7E-11 T 28-03-2018 IPR006343 DnaD domain A21D_RS02060 f34f4db995575df6639c82279222bf42 161 SUPERFAMILY SSF55252 87 152 4.84E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 PRINTS PR01467 Bacterial arginine repressor signature 26 39 1.1E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 PRINTS PR01467 Bacterial arginine repressor signature 95 108 1.1E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 PRINTS PR01467 Bacterial arginine repressor signature 42 57 1.1E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 PRINTS PR01467 Bacterial arginine repressor signature 125 140 1.1E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 155 6.0E-12 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 Hamap MF_00173 Arginine repressor [argR]. 1 159 44.028 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 Gene3D G3DSA:3.30.1360.40 81 153 1.2E-19 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 Pfam PF01316 Arginine repressor, DNA binding domain 6 72 5.6E-19 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A21D_RS02060 f34f4db995575df6639c82279222bf42 161 SUPERFAMILY SSF46785 5 72 1.58E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02060 f34f4db995575df6639c82279222bf42 161 Gene3D G3DSA:1.10.10.10 4 73 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02060 f34f4db995575df6639c82279222bf42 161 Pfam PF02863 Arginine repressor, C-terminal domain 87 151 6.0E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS04380 e977459300763d33c04e26688c8def3b 430 PIRSF PIRSF006351 1 430 2.7E-134 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS04380 e977459300763d33c04e26688c8def3b 430 Pfam PF02378 Phosphotransferase system, EIIC 26 353 1.4E-51 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS04380 e977459300763d33c04e26688c8def3b 430 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 10 423 7.3E-126 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SMART SM00530 7 61 7.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Gene3D G3DSA:1.25.40.10 358 424 0.073 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Gene3D G3DSA:1.25.40.10 277 336 4.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SUPERFAMILY SSF47413 2 59 3.66E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SMART SM00028 304 337 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SMART SM00028 389 422 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SMART SM00028 226 259 2.3 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SMART SM00028 266 299 0.059 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Gene3D G3DSA:1.10.260.40 2 65 6.1E-12 T 28-03-2018 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 SUPERFAMILY SSF48452 147 339 4.55E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Pfam PF01381 Helix-turn-helix 8 60 1.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Gene3D G3DSA:1.25.40.10 222 276 6.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16935 86cc3c2d5c8d0662fb2ad9525aa6a211 425 Gene3D G3DSA:1.25.40.10 66 196 1.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 Gene3D G3DSA:1.10.155.10 2 66 2.1E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 Gene3D G3DSA:3.40.50.150 67 256 3.9E-48 T 28-03-2018 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 Pfam PF01739 CheR methyltransferase, SAM binding domain 68 244 1.8E-60 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 SUPERFAMILY SSF47757 3 67 4.71E-12 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 PRINTS PR00996 Glutamate methyltransferase family signature 61 73 4.5E-39 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 Pfam PF03705 CheR methyltransferase, all-alpha domain 3 55 7.9E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 SMART SM00138 2 254 1.8E-103 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A21D_RS16610 de0d1dc44f1af32dc71dc7ce42431ff5 257 SUPERFAMILY SSF53335 68 252 2.91E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS03335 9fc01a54129ecc04523c502871caca80 150 Pfam PF07997 Protein of unknown function (DUF1694) 3 119 3.7E-32 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 A21D_RS03335 9fc01a54129ecc04523c502871caca80 150 SUPERFAMILY SSF160515 3 127 5.75E-31 T 28-03-2018 A21D_RS03335 9fc01a54129ecc04523c502871caca80 150 Gene3D G3DSA:3.30.1330.30 4 124 5.2E-36 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS03335 9fc01a54129ecc04523c502871caca80 150 PIRSF PIRSF034303 1 150 4.1E-42 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 A21D_RS16830 8845b0080594049c41064229058087a7 560 SUPERFAMILY SSF52091 417 522 3.53E-15 T 28-03-2018 IPR002645 STAS domain A21D_RS16830 8845b0080594049c41064229058087a7 560 Gene3D G3DSA:3.30.750.24 364 526 3.1E-18 T 28-03-2018 IPR002645 STAS domain A21D_RS16830 8845b0080594049c41064229058087a7 560 Pfam PF01740 STAS domain 424 520 5.9E-13 T 28-03-2018 IPR002645 STAS domain A21D_RS16830 8845b0080594049c41064229058087a7 560 Pfam PF00916 Sulfate permease family 2 361 3.1E-88 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 7.9E-128 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 Gene3D G3DSA:3.90.226.10 1 211 1.8E-63 T 28-03-2018 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 Gene3D G3DSA:1.10.12.10 212 260 9.3E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.36 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 266 2.0E-86 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS14085 29f691dc1c4941942edec05ebe842cef 272 SUPERFAMILY SSF52096 5 268 6.26E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS01910 e8cb639f4846dfb5ca969abb56ebb331 448 Pfam PF03611 PTS system sugar-specific permease component 10 384 2.7E-62 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS01910 e8cb639f4846dfb5ca969abb56ebb331 448 PIRSF PIRSF006304 4 448 7.6E-139 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 A21D_RS18350 55fbb969bbea9ec0c24db89d6e38b4ed 88 SUPERFAMILY SSF50346 1 77 2.08E-11 T 28-03-2018 IPR011033 PRC-barrel-like A21D_RS18350 55fbb969bbea9ec0c24db89d6e38b4ed 88 Pfam PF05239 PRC-barrel domain 2 77 1.5E-12 T 28-03-2018 IPR027275 PRC-barrel domain A21D_RS18350 55fbb969bbea9ec0c24db89d6e38b4ed 88 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 9.3E-24 T 28-03-2018 IPR014238 Sporulation protein YlmC/YmxH A21D_RS18350 55fbb969bbea9ec0c24db89d6e38b4ed 88 Gene3D G3DSA:2.30.30.240 1 79 3.2E-15 T 28-03-2018 A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 SUPERFAMILY SSF69754 2 110 3.66E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 5.2E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 94 6.5E-29 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 184 25.074 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 180 1.1E-28 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A21D_RS00810 c836475e1e61020c1df092a3e147baac 185 Gene3D G3DSA:3.30.160.100 1 101 1.6E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A21D_RS18980 a60cf04acde5579eb3a5c707e9711cc5 381 SUPERFAMILY SSF103473 4 372 2.62E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS18980 a60cf04acde5579eb3a5c707e9711cc5 381 Pfam PF07690 Major Facilitator Superfamily 5 282 6.7E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS18980 a60cf04acde5579eb3a5c707e9711cc5 381 Gene3D G3DSA:1.20.1250.20 3 179 9.3E-32 T 28-03-2018 A21D_RS18980 a60cf04acde5579eb3a5c707e9711cc5 381 Gene3D G3DSA:1.20.1250.20 188 381 4.6E-27 T 28-03-2018 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 SUPERFAMILY SSF56059 140 356 4.95E-63 T 28-03-2018 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 43.004 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 3.2E-76 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Gene3D G3DSA:3.30.1490.20 141 213 4.6E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Gene3D G3DSA:3.30.470.20 214 360 9.0E-44 T 28-03-2018 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 PIRSF PIRSF039102 1 359 4.2E-135 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Pfam PF01820 D-ala D-ala ligase N-terminus 5 129 3.7E-32 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 Gene3D G3DSA:3.40.50.20 1 140 1.8E-46 T 28-03-2018 A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 SUPERFAMILY SSF52440 3 139 4.99E-38 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS03190 3964b406be3bb05aee1cada334c4dfd1 366 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 1.6E-114 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 110.574 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 Pfam PF02132 RecR protein 39 78 3.8E-17 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 Gene3D G3DSA:1.10.150.20 8 30 0.0013 T 28-03-2018 A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 SUPERFAMILY SSF111304 1 198 2.48E-78 T 28-03-2018 IPR023627 Recombination protein RecR A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 SMART SM00493 80 165 2.8E-17 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 Gene3D G3DSA:3.40.1360.10 77 170 1.1E-38 T 28-03-2018 A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 Pfam PF13662 Toprim domain 80 171 1.6E-22 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS06890 b43854bbbdeda2fd4e3ddf3b5cfda22b 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 8.2E-89 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 Gene3D G3DSA:3.40.50.2300 1 130 4.2E-10 T 28-03-2018 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 Gene3D G3DSA:3.90.1240.10 288 516 2.3E-19 T 28-03-2018 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 441 483 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 SUPERFAMILY SSF46689 440 492 4.21E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 Pfam PF12833 Helix-turn-helix domain 411 488 6.9E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 471 487 5.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 456 471 5.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 SUPERFAMILY SSF52172 1 131 2.41E-10 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 SMART SM00342 405 487 5.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS12535 b70898eddce399bcdd229dfc47a9549c 518 Pfam PF00072 Response regulator receiver domain 3 114 9.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 SUPERFAMILY SSF53187 377 440 5.91E-56 T 28-03-2018 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 SUPERFAMILY SSF53187 5 196 5.91E-56 T 28-03-2018 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 424 1.8E-89 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 Gene3D G3DSA:3.40.630.10 373 459 4.3E-14 T 28-03-2018 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 Gene3D G3DSA:3.40.630.10 1 304 9.1E-45 T 28-03-2018 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 PIRSF PIRSF037227 1 475 1.7E-214 T 28-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 Pfam PF01546 Peptidase family M20/M25/M40 77 167 2.6E-7 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS10695 730102ec11c46638b7423ee9c1d73d3c 475 SUPERFAMILY SSF55031 185 289 4.06E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS07490 06e307464034f105dedc5b70b5655c4e 201 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 3.3E-83 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A21D_RS07490 06e307464034f105dedc5b70b5655c4e 201 SUPERFAMILY SSF52540 22 196 2.91E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07490 06e307464034f105dedc5b70b5655c4e 201 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 39.28 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A21D_RS07490 06e307464034f105dedc5b70b5655c4e 201 Pfam PF01583 Adenylylsulphate kinase 26 180 5.9E-72 T 28-03-2018 A21D_RS07490 06e307464034f105dedc5b70b5655c4e 201 Gene3D G3DSA:3.40.50.300 22 201 7.1E-52 T 28-03-2018 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 2.6E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 Gene3D G3DSA:3.40.47.10 6 259 3.7E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 SUPERFAMILY SSF53901 4 251 3.94E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 Gene3D G3DSA:3.40.47.10 262 413 2.2E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 SUPERFAMILY SSF53901 214 411 3.6E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 2.2E-198 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 SMART SM00825 Beta-ketoacyl synthase 6 413 2.7E-17 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 PIRSF PIRSF000447 1 413 7.3E-188 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A21D_RS13420 5bff2b9aa43730371ce9fb62fb823025 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 8.8E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A21D_RS08420 fcd8d480dd5e523c89679c9cf94777da 451 Pfam PF03616 Sodium/glutamate symporter 14 344 2.5E-17 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 Gene3D G3DSA:2.30.33.40 1 94 1.6E-39 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 26.473 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 SUPERFAMILY SSF50129 1 93 4.59E-35 T 28-03-2018 IPR011032 GroES-like A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 SMART SM00883 1 93 1.2E-56 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.6E-37 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 PRINTS PR00297 10kDa chaperonin signature 2 17 7.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 PRINTS PR00297 10kDa chaperonin signature 59 71 7.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 PRINTS PR00297 10kDa chaperonin signature 24 45 7.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS10220 ce5462860fdbc0390229287a8bb9e3bc 94 PRINTS PR00297 10kDa chaperonin signature 80 93 7.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A21D_RS13090 d8fc0b0bab23806a35704ac71e3392e7 111 SUPERFAMILY SSF109915 2 108 4.18E-27 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 A21D_RS13090 d8fc0b0bab23806a35704ac71e3392e7 111 ProDom PD073069 YHAI 3D-STRUCTURE 10 109 8.0E-12 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 A21D_RS13090 d8fc0b0bab23806a35704ac71e3392e7 111 Pfam PF08963 Protein of unknown function (DUF1878) 3 106 6.5E-26 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 A21D_RS13090 d8fc0b0bab23806a35704ac71e3392e7 111 Gene3D G3DSA:1.10.3750.10 1 105 3.2E-33 T 28-03-2018 IPR015058 Protein of unknown function DUF1878 A21D_RS11240 c08baaca5f3289e3d4af10ceed0486a0 68 SUPERFAMILY SSF140500 9 51 1.83E-12 T 28-03-2018 A21D_RS11240 c08baaca5f3289e3d4af10ceed0486a0 68 Pfam PF09388 Spo0E like sporulation regulatory protein 15 48 5.8E-12 T 28-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A21D_RS07775 1c18388429764bda4f13ac28330913c8 335 Gene3D G3DSA:1.10.287.130 127 192 6.8E-6 T 28-03-2018 A21D_RS07775 1c18388429764bda4f13ac28330913c8 335 SUPERFAMILY SSF47384 120 190 3.53E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS07775 1c18388429764bda4f13ac28330913c8 335 SUPERFAMILY SSF55874 206 331 8.12E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07775 1c18388429764bda4f13ac28330913c8 335 Gene3D G3DSA:3.30.565.10 193 334 2.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS02225 9ad2b3ec24847ec89ccd167a986f1779 571 Pfam PF09972 Predicted membrane protein (DUF2207) 28 461 2.6E-49 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 SUPERFAMILY SSF51556 63 359 7.42E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 8 386 2.1E-116 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 SUPERFAMILY SSF51338 7 62 8.54E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 SUPERFAMILY SSF51338 359 392 8.54E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 Gene3D G3DSA:3.20.20.140 78 359 2.8E-101 T 28-03-2018 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 Pfam PF01979 Amidohydrolase family 60 387 7.2E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 PIRSF PIRSF038994 6 392 2.2E-128 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A21D_RS00935 b9adae8a7f1e571690587031d3cbbabf 401 Gene3D G3DSA:2.30.40.10 6 77 1.7E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 276 404 2.8E-4 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 32 205 1.6E-36 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 Gene3D G3DSA:3.40.640.10 21 301 7.0E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 SUPERFAMILY SSF53383 33 221 1.75E-53 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 SUPERFAMILY SSF53383 274 413 1.75E-53 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 Gene3D G3DSA:3.90.1150.10 302 416 5.0E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 PIRSF PIRSF000390 246 415 0.012 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS08640 7d2437df993eece01594364acdd3bb93 419 PIRSF PIRSF000390 9 212 1.1E-39 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 209 1.3E-33 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 107 206 7.8E-32 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 210 22.262 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 SUPERFAMILY SSF63848 104 209 1.7E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 Gene3D G3DSA:2.160.20.70 97 213 3.8E-36 T 28-03-2018 A21D_RS15195 0972d9aaf78fe1ffb0adb96e18b6e8e4 229 Gene3D G3DSA:3.30.750.50 9 96 5.8E-24 T 28-03-2018 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 Gene3D G3DSA:3.40.190.10 94 174 1.0E-23 T 28-03-2018 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 SUPERFAMILY SSF53850 4 187 1.74E-50 T 28-03-2018 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 PIRSF PIRSF001500 2 285 5.6E-69 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 Gene3D G3DSA:3.40.190.10 1 93 5.9E-25 T 28-03-2018 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 160 182 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 Pfam PF00800 Prephenate dehydratase 5 186 1.5E-56 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 SUPERFAMILY SSF55021 179 279 8.02E-22 T 28-03-2018 A21D_RS15240 5863dc66eb8e08870db5cc6b1b3a7463 286 Gene3D G3DSA:3.30.70.260 190 285 1.1E-20 T 28-03-2018 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 Gene3D G3DSA:2.40.40.20 1 117 1.3E-47 T 28-03-2018 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 Pfam PF02261 Aspartate decarboxylase 1 114 2.3E-45 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 57.046 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 SUPERFAMILY SSF50692 1 117 1.99E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 3.0E-39 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 PIRSF PIRSF006246 1 129 6.5E-45 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A21D_RS01810 bb25ca5850ee1bd594dd8833eab13b07 130 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 6.0E-25 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A21D_RS07555 266a7a1b624fb6181149f0bc88aae0ba 282 Pfam PF02666 Phosphatidylserine decarboxylase 80 277 1.5E-51 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A21D_RS07555 266a7a1b624fb6181149f0bc88aae0ba 282 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 68 228 6.0E-43 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A21D_RS04205 11c9cf3963f5a5528f9bca90fbd5f52f 132 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 2.5E-60 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 A21D_RS04205 11c9cf3963f5a5528f9bca90fbd5f52f 132 Gene3D G3DSA:3.40.50.620 1 129 3.0E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS04205 11c9cf3963f5a5528f9bca90fbd5f52f 132 SUPERFAMILY SSF52374 1 124 4.65E-34 T 28-03-2018 A21D_RS04205 11c9cf3963f5a5528f9bca90fbd5f52f 132 Pfam PF01467 Cytidylyltransferase-like 5 114 1.8E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS04205 11c9cf3963f5a5528f9bca90fbd5f52f 132 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 1.9E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 Pfam PF00005 ABC transporter 354 502 2.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 Pfam PF00664 ABC transporter transmembrane region 23 291 3.6E-22 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 SMART SM00382 362 547 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 Gene3D G3DSA:1.20.1560.10 2 324 9.1E-39 T 28-03-2018 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 SUPERFAMILY SSF52540 332 572 6.1E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 Gene3D G3DSA:3.40.50.300 325 578 4.0E-78 T 28-03-2018 A21D_RS06055 d3d6253bf68dcda4b6e1ff9db53a92b2 590 SUPERFAMILY SSF90123 10 319 3.01E-53 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 427 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 454 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 282 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 347 368 1.1E-74 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Gene3D G3DSA:1.10.287.990 41 110 1.6E-20 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Gene3D G3DSA:3.30.390.30 362 470 4.9E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Gene3D G3DSA:3.50.50.60 121 256 1.0E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 5.4E-41 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 5.4E-41 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 5.4E-41 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 5.4E-41 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 5.4E-41 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 SUPERFAMILY SSF55424 347 469 1.32E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 11 470 2.5E-164 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 351 459 3.2E-33 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 PIRSF PIRSF000350 2 463 1.8E-103 T 28-03-2018 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 331 1.9E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 SUPERFAMILY SSF51905 9 340 4.81E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05925 f9033e6fd91428e78636604393b48587 470 Gene3D G3DSA:3.50.50.60 273 361 1.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 Gene3D G3DSA:3.20.20.80 3 466 2.5E-148 T 28-03-2018 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 SUPERFAMILY SSF51445 2 457 1.58E-162 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 4.5E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 4.5E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 361 369 4.5E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 4.5E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 4.5E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 361 369 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site A21D_RS09395 357c65ffa5919b604fec2fd962703654 466 Pfam PF00232 Glycosyl hydrolase family 1 4 462 8.4E-138 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12715 9b9038bd9c217645617033a66db64214 193 Gene3D G3DSA:3.40.50.2020 3 188 5.9E-21 T 28-03-2018 A21D_RS12715 9b9038bd9c217645617033a66db64214 193 SUPERFAMILY SSF53271 1 189 1.38E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS12715 9b9038bd9c217645617033a66db64214 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.583 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A21D_RS12715 9b9038bd9c217645617033a66db64214 193 Pfam PF00156 Phosphoribosyl transferase domain 37 157 1.3E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS12715 9b9038bd9c217645617033a66db64214 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 191 2.7E-84 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 Gene3D G3DSA:3.40.50.300 1 239 1.2E-77 T 28-03-2018 A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 SUPERFAMILY SSF52540 1 235 1.94E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 PIRSF PIRSF039085 1 240 9.0E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 SMART SM00382 26 213 2.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS02910 201934c785d433e5cd129c9c7200c729 240 Pfam PF00005 ABC transporter 17 165 9.0E-40 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11230 a61ac32c848e6aa8d39fc31097217195 478 Gene3D G3DSA:1.10.4100.10 1 326 2.1E-95 T 28-03-2018 A21D_RS11230 a61ac32c848e6aa8d39fc31097217195 478 SUPERFAMILY SSF103378 10 476 2.09E-153 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 A21D_RS11230 a61ac32c848e6aa8d39fc31097217195 478 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 11 477 2.1E-261 T 28-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 A21D_RS11230 a61ac32c848e6aa8d39fc31097217195 478 Pfam PF03972 MmgE/PrpD family 15 456 5.2E-146 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 A21D_RS11230 a61ac32c848e6aa8d39fc31097217195 478 Gene3D G3DSA:1.10.4100.10 389 478 1.2E-11 T 28-03-2018 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 Gene3D G3DSA:3.20.20.60 1 406 5.2E-150 T 28-03-2018 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 PIRSF PIRSF001362 1 425 4.5E-238 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 SUPERFAMILY SSF51621 4 423 4.31E-158 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 Pfam PF00463 Isocitrate lyase family 248 423 1.6E-54 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 Pfam PF00463 Isocitrate lyase family 7 246 2.0E-58 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 6 246 9.2E-106 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 247 423 1.0E-82 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A21D_RS00355 9251a96d3602d773bf1998ba1ee13bea 425 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 427 2.3E-168 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 SUPERFAMILY SSF53383 1 426 3.37E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 Gene3D G3DSA:3.40.640.10 176 314 3.3E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 Pfam PF00202 Aminotransferase class-III 36 398 2.5E-69 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 93.427 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 Gene3D G3DSA:3.90.1150.10 315 430 9.8E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS11725 98645521084c1ca802b3e631851dc9d2 431 Gene3D G3DSA:3.90.1150.10 1 175 7.9E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS16915 45860cbe360c4e56726df93830563878 79 Gene3D G3DSA:3.30.70.20 45 79 1.2E-10 T 28-03-2018 A21D_RS16915 45860cbe360c4e56726df93830563878 79 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.0E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS16915 45860cbe360c4e56726df93830563878 79 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.0E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS16915 45860cbe360c4e56726df93830563878 79 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.0E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS16915 45860cbe360c4e56726df93830563878 79 SUPERFAMILY SSF54862 3 75 2.93E-20 T 28-03-2018 A21D_RS16915 45860cbe360c4e56726df93830563878 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS16915 45860cbe360c4e56726df93830563878 79 Pfam PF00037 4Fe-4S binding domain 34 56 4.4E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS16915 45860cbe360c4e56726df93830563878 79 Gene3D G3DSA:3.30.70.20 2 44 4.9E-14 T 28-03-2018 A21D_RS18935 3a5358ee071a3bed7366259b0f0c7ec5 469 Pfam PF03616 Sodium/glutamate symporter 12 368 6.6E-14 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 SUPERFAMILY SSF52540 2 228 2.22E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 SMART SM00382 27 212 1.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 3 268 2.4E-108 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 Pfam PF00005 ABC transporter 19 165 3.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04960 3ea616de8545f4f09a26a4ac3f06c840 271 Gene3D G3DSA:3.40.50.300 1 237 9.8E-67 T 28-03-2018 A21D_RS09420 4f7e1457f394da1005889dc347107e23 488 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 8 98 5.2E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS09420 4f7e1457f394da1005889dc347107e23 488 Gene3D G3DSA:3.40.50.2300 5 103 1.3E-39 T 28-03-2018 A21D_RS09420 4f7e1457f394da1005889dc347107e23 488 SUPERFAMILY SSF52794 5 105 1.08E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS09420 4f7e1457f394da1005889dc347107e23 488 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 120 484 2.1E-68 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A21D_RS09420 4f7e1457f394da1005889dc347107e23 488 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 7 90 1.2E-31 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A21D_RS09965 e18199df847568037dee7d4534e6cd44 284 Gene3D G3DSA:3.30.1180.10 157 283 2.1E-30 T 28-03-2018 A21D_RS09965 e18199df847568037dee7d4534e6cd44 284 SUPERFAMILY SSF82549 1 283 3.92E-73 T 28-03-2018 A21D_RS09965 e18199df847568037dee7d4534e6cd44 284 Gene3D G3DSA:3.40.50.10170 1 156 2.0E-37 T 28-03-2018 A21D_RS09965 e18199df847568037dee7d4534e6cd44 284 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 281 8.6E-76 T 28-03-2018 IPR003797 DegV A21D_RS09965 e18199df847568037dee7d4534e6cd44 284 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 283 8.9E-66 T 28-03-2018 IPR003797 DegV A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 Gene3D G3DSA:3.90.110.10 157 442 9.4E-84 T 28-03-2018 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 Gene3D G3DSA:3.40.50.720 2 156 6.6E-23 T 28-03-2018 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 139 170 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 SUPERFAMILY SSF51735 5 166 1.73E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 96 109 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 75 91 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 5.8E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 418 9.3E-51 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 Pfam PF02056 Family 4 glycosyl hydrolase 7 185 2.0E-63 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS08070 23f2ed96b67486c772b5dcefacd81f93 443 SUPERFAMILY SSF56327 169 442 2.66E-88 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 Pfam PF01597 Glycine cleavage H-protein 7 125 8.0E-49 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 Gene3D G3DSA:2.40.50.100 5 126 8.4E-50 T 28-03-2018 A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.532 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 2.1E-54 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A21D_RS00270 6e3691893f76822808250e9d31c6d7ba 126 SUPERFAMILY SSF51230 3 125 9.29E-46 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 Pfam PF07698 7TM receptor with intracellular HD hydrolase 262 460 9.2E-38 T 28-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 SMART SM00471 481 636 3.2E-11 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 TIGRFAM TIGR00277 HDIG: HDIG domain 482 580 1.4E-25 T 28-03-2018 IPR006675 HDIG domain A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 SUPERFAMILY SSF109604 480 661 6.0E-16 T 28-03-2018 A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 Pfam PF01966 HD domain 485 626 7.5E-20 T 28-03-2018 IPR006674 HD domain A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 Pfam PF07697 7TM-HD extracellular 33 255 1.9E-34 T 28-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain A21D_RS15710 2cbe927279b54162332cc60c2007b765 693 Gene3D G3DSA:1.10.3210.10 431 673 1.4E-35 T 28-03-2018 A21D_RS01495 238aa83636f9d159ed181dc4547fc648 117 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 109 7.2E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A21D_RS01495 238aa83636f9d159ed181dc4547fc648 117 Gene3D G3DSA:1.20.1290.10 1 117 6.1E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A21D_RS01495 238aa83636f9d159ed181dc4547fc648 117 SUPERFAMILY SSF69118 10 115 1.27E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 27.548 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Gene3D G3DSA:4.10.860.10 175 235 4.7E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 SUPERFAMILY SSF46600 183 235 1.31E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Gene3D G3DSA:3.40.1440.10 1 98 1.6E-25 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 569 2.4E-209 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Gene3D G3DSA:1.10.150.20 522 595 3.0E-14 T 28-03-2018 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 SMART SM00465 15 95 2.8E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 371 523 1.2E-53 T 28-03-2018 IPR001162 UvrC family homology region A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Pfam PF02151 UvrB/uvrC motif 199 229 3.3E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 Pfam PF01541 GIY-YIG catalytic domain 16 90 1.3E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 SUPERFAMILY SSF47781 502 589 5.08E-19 T 28-03-2018 IPR010994 RuvA domain 2-like A21D_RS14815 7d2ff444e3b6aaad0ee0864ccb94768c 596 SUPERFAMILY SSF82771 15 97 6.28E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A21D_RS01340 47dc98aa7f54d3ed6db42aaae59c9738 71 SMART SM00530 9 64 2.0E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS01340 47dc98aa7f54d3ed6db42aaae59c9738 71 SUPERFAMILY SSF47413 3 69 1.07E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS01340 47dc98aa7f54d3ed6db42aaae59c9738 71 Gene3D G3DSA:3.30.1190.10 28 71 1.7E-11 T 28-03-2018 A21D_RS01340 47dc98aa7f54d3ed6db42aaae59c9738 71 Gene3D G3DSA:1.10.10.10 3 27 8.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01340 47dc98aa7f54d3ed6db42aaae59c9738 71 Pfam PF01381 Helix-turn-helix 10 63 3.8E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS07670 8f17750309c154f78f49f5477b33aa1f 132 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS07670 8f17750309c154f78f49f5477b33aa1f 132 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS07670 8f17750309c154f78f49f5477b33aa1f 132 Gene3D G3DSA:3.90.79.10 2 131 7.4E-27 T 28-03-2018 A21D_RS07670 8f17750309c154f78f49f5477b33aa1f 132 Pfam PF00293 NUDIX domain 7 119 1.4E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS07670 8f17750309c154f78f49f5477b33aa1f 132 SUPERFAMILY SSF55811 2 126 3.38E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 1.9E-34 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 SUPERFAMILY SSF55200 84 173 7.72E-36 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 171 8.6E-75 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 3.3E-40 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 SUPERFAMILY SSF54364 7 80 1.83E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 Gene3D G3DSA:3.30.110.10 81 173 8.5E-38 T 28-03-2018 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 32.365 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 A21D_RS14670 830d48a4a765eecefa07a042996824ba 173 Gene3D G3DSA:3.10.20.80 4 80 5.5E-34 T 28-03-2018 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 Gene3D G3DSA:3.40.309.10 269 462 1.1E-71 T 28-03-2018 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 SUPERFAMILY SSF53720 4 478 6.54E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 Gene3D G3DSA:3.40.605.10 1 268 1.0E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 9 490 9.4E-241 T 28-03-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 A21D_RS19390 3920ed8717eaef9300f9f3cfa1e1b6bd 490 Pfam PF00171 Aldehyde dehydrogenase family 18 475 4.7E-172 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01035 0a942289017ce6161f193d68d21d067c 817 Gene3D G3DSA:3.30.470.20 308 444 4.2E-13 T 28-03-2018 A21D_RS01035 0a942289017ce6161f193d68d21d067c 817 Pfam PF14398 YheC/D like ATP-grasp 208 452 2.7E-47 T 28-03-2018 IPR026838 Endospore coat-associated protein YheC/D A21D_RS01035 0a942289017ce6161f193d68d21d067c 817 SUPERFAMILY SSF56059 228 439 1.26E-9 T 28-03-2018 A21D_RS01035 0a942289017ce6161f193d68d21d067c 817 Gene3D G3DSA:3.30.1490.20 240 307 1.8E-7 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS01035 0a942289017ce6161f193d68d21d067c 817 Gene3D G3DSA:3.30.1490.20 602 628 0.12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS09415 2efc9a41825a64f2584f40b68f98471c 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 4.5E-38 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS09415 2efc9a41825a64f2584f40b68f98471c 154 Gene3D G3DSA:3.40.930.10 1 149 4.7E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS09415 2efc9a41825a64f2584f40b68f98471c 154 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 132 8.1E-35 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A21D_RS09415 2efc9a41825a64f2584f40b68f98471c 154 SUPERFAMILY SSF55804 1 147 1.19E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS16900 bef153af68f2593d924aa6739e0e8cbb 185 Pfam PF14181 YqfQ-like protein 49 182 5.8E-18 T 28-03-2018 IPR025571 YqfQ-like protein A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 SMART SM00354 1 71 6.5E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 SUPERFAMILY SSF47413 3 49 1.92E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Gene3D G3DSA:3.40.50.2300 177 315 2.7E-34 T 28-03-2018 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Pfam PF13377 Periplasmic binding protein-like domain 171 332 2.6E-36 T 28-03-2018 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Gene3D G3DSA:3.40.50.2300 64 176 2.5E-10 T 28-03-2018 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Gene3D G3DSA:1.10.260.40 16 63 4.5E-17 T 28-03-2018 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 SUPERFAMILY SSF53822 74 333 3.26E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 7.6E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS05790 19c780cff45a31a8a33d760afb0ebe2a 337 Gene3D G3DSA:1.10.10.60 2 15 0.37 T 28-03-2018 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 212 3.7E-91 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 PIRSF PIRSF001461 1 220 5.9E-96 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 Gene3D G3DSA:3.20.20.70 1 217 5.1E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.5E-84 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 SUPERFAMILY SSF51366 1 216 4.64E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS18170 40f184255eff3ee5ce0bdfa79568b2c0 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS07715 2ee1264c6ee6af459913f6c53652933d 56 Pfam PF12669 Virus attachment protein p12 family 4 44 7.3E-9 T 28-03-2018 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 510 2.0E-208 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 SMART SM00798 134 445 6.1E-187 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 SUPERFAMILY SSF52335 2 192 1.78E-66 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Gene3D G3DSA:3.40.140.20 359 500 3.4E-50 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Gene3D G3DSA:3.40.50.1380 1 191 9.0E-71 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 PIRSF PIRSF000414 1 510 8.3E-210 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 444 1.0E-118 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 SMART SM00851 14 129 4.9E-45 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Gene3D G3DSA:3.40.140.20 213 358 1.0E-52 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 SUPERFAMILY SSF53927 205 510 3.91E-124 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 510 43.287 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A21D_RS10970 7caf5e1c250455fbf2dc77fdadbe87d7 510 Pfam PF02142 MGS-like domain 14 128 3.6E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 ProSitePatterns PS00151 Acylphosphatase signature 2. 31 47 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 PRINTS PR00112 Acylphosphatase signature 23 48 4.5E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 PRINTS PR00112 Acylphosphatase signature 2 17 4.5E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 Gene3D G3DSA:3.30.70.100 1 89 1.0E-26 T 28-03-2018 A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 Pfam PF00708 Acylphosphatase 4 87 2.3E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A21D_RS16920 ed6c729930bb6d8313ba20b4b02d1e1e 89 SUPERFAMILY SSF54975 2 88 5.89E-25 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 SUPERFAMILY SSF51735 4 222 5.34E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 0.0025 T 28-03-2018 A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 Gene3D G3DSA:3.40.50.720 2 220 3.4E-59 T 28-03-2018 A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 Pfam PF00106 short chain dehydrogenase 8 194 3.5E-56 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02820 3646ce641f125aeb3af6dbc467718914 240 PIRSF PIRSF000126 1 239 1.0E-58 T 28-03-2018 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 SUPERFAMILY SSF55120 75 294 2.72E-68 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 129 143 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 Pfam PF00849 RNA pseudouridylate synthase 86 236 1.7E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 Gene3D G3DSA:3.10.290.10 1 69 4.8E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 Gene3D G3DSA:3.30.2350.10 77 297 1.7E-66 T 28-03-2018 A21D_RS13520 23e48a4a4665a8b3886490aa5b358b68 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 293 1.2E-76 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS11305 0040d26d7820c84b83baaa2f6b71dd2f 328 Gene3D G3DSA:3.60.70.12 1 328 4.1E-96 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A21D_RS11305 0040d26d7820c84b83baaa2f6b71dd2f 328 Pfam PF03576 Peptidase family S58 9 322 6.4E-106 T 28-03-2018 IPR005321 Peptidase S58, DmpA A21D_RS11305 0040d26d7820c84b83baaa2f6b71dd2f 328 SUPERFAMILY SSF56266 2 320 8.89E-93 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A21D_RS14295 d609659d6f56ba16d507285dae10a68a 105 SUPERFAMILY SSF52833 3 102 3.68E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS14295 d609659d6f56ba16d507285dae10a68a 105 Pfam PF00085 Thioredoxin 5 101 3.3E-18 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS14295 d609659d6f56ba16d507285dae10a68a 105 Gene3D G3DSA:3.40.30.10 1 103 1.2E-22 T 28-03-2018 A21D_RS09605 4909ff7b112f4e18a6d7c8ff7012fe09 243 Pfam PF03073 TspO/MBR family 12 153 4.6E-9 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 A21D_RS12970 e30471d84203bf71a130d748c7cae7ac 365 SUPERFAMILY SSF53474 235 328 5.22E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12970 e30471d84203bf71a130d748c7cae7ac 365 SUPERFAMILY SSF53474 62 200 5.22E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12970 e30471d84203bf71a130d748c7cae7ac 365 Gene3D G3DSA:3.40.50.1820 57 346 8.8E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12970 e30471d84203bf71a130d748c7cae7ac 365 Pfam PF12146 Serine aminopeptidase, S33 101 325 9.1E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A21D_RS01545 0d87b8dd054884cfe08208a473f9bc45 184 Gene3D G3DSA:3.40.50.450 1 177 1.6E-32 T 28-03-2018 A21D_RS01545 0d87b8dd054884cfe08208a473f9bc45 184 PIRSF PIRSF021290 1 176 1.6E-58 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 A21D_RS01545 0d87b8dd054884cfe08208a473f9bc45 184 SUPERFAMILY SSF102405 1 174 4.21E-51 T 28-03-2018 A21D_RS01545 0d87b8dd054884cfe08208a473f9bc45 184 Pfam PF06908 Protein of unknown function (DUF1273) 4 168 3.2E-56 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 A21D_RS04395 c13b23159356f6557ebbf1f8853818a2 232 Gene3D G3DSA:3.20.20.370 1 231 1.3E-64 T 28-03-2018 A21D_RS04395 c13b23159356f6557ebbf1f8853818a2 232 SUPERFAMILY SSF88713 1 231 2.45E-59 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS04395 c13b23159356f6557ebbf1f8853818a2 232 Pfam PF04794 YdjC-like protein 2 230 7.4E-51 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like A21D_RS14185 d7dc542b5ffd85503ec573d4f04e4b3d 198 Gene3D G3DSA:3.40.50.150 6 187 3.5E-23 T 28-03-2018 A21D_RS14185 d7dc542b5ffd85503ec573d4f04e4b3d 198 SUPERFAMILY SSF53335 11 186 1.52E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS14185 d7dc542b5ffd85503ec573d4f04e4b3d 198 Pfam PF06962 Putative rRNA methylase 47 185 1.6E-51 T 28-03-2018 IPR010719 Putative rRNA methylase A21D_RS09970 9571ebe003721a8681157f17b18bb66c 305 SUPERFAMILY SSF103481 40 143 1.83E-16 T 28-03-2018 A21D_RS09970 9571ebe003721a8681157f17b18bb66c 305 Pfam PF00892 EamA-like transporter family 9 140 1.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS09970 9571ebe003721a8681157f17b18bb66c 305 Pfam PF00892 EamA-like transporter family 152 286 1.4E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS09970 9571ebe003721a8681157f17b18bb66c 305 SUPERFAMILY SSF103481 192 291 3.27E-13 T 28-03-2018 A21D_RS16260 2d2e85db9c7a0df00dc5f1ea601c9be4 305 Gene3D G3DSA:3.60.15.10 1 305 2.1E-62 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS16260 2d2e85db9c7a0df00dc5f1ea601c9be4 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 9.1E-117 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A21D_RS16260 2d2e85db9c7a0df00dc5f1ea601c9be4 305 Pfam PF00753 Metallo-beta-lactamase superfamily 26 122 1.1E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS16260 2d2e85db9c7a0df00dc5f1ea601c9be4 305 Hamap MF_01818 Ribonuclease BN [rbn]. 1 304 40.281 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A21D_RS16260 2d2e85db9c7a0df00dc5f1ea601c9be4 305 SUPERFAMILY SSF56281 1 304 8.53E-83 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 231 1.6E-25 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SUPERFAMILY SSF54184 614 669 4.06E-9 T 28-03-2018 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Gene3D G3DSA:3.90.1310.10 23 247 5.2E-38 T 28-03-2018 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 593 4.1E-81 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SMART SM00740 611 670 1.2E-6 T 28-03-2018 IPR005543 PASTA domain A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SMART SM00740 672 726 0.57 T 28-03-2018 IPR005543 PASTA domain A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SUPERFAMILY SSF56601 201 611 4.44E-88 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SUPERFAMILY SSF56519 55 250 7.06E-42 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Pfam PF03793 PASTA domain 615 667 1.2E-8 T 28-03-2018 IPR005543 PASTA domain A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Pfam PF03793 PASTA domain 672 718 3.1E-6 T 28-03-2018 IPR005543 PASTA domain A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 SUPERFAMILY SSF54184 672 724 2.62E-11 T 28-03-2018 A21D_RS18415 135bd8f2da406e4ec8f915104d8a265c 734 Gene3D G3DSA:3.40.710.10 248 599 7.6E-84 T 28-03-2018 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 SUPERFAMILY SSF51735 116 292 2.04E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 Gene3D G3DSA:3.40.50.720 140 294 1.7E-11 T 28-03-2018 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 Pfam PF00107 Zinc-binding dehydrogenase 161 258 9.1E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 7.5E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 SMART SM00829 13 326 4.4E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 Gene3D G3DSA:3.90.180.10 3 139 8.0E-30 T 28-03-2018 A21D_RS04995 22dc96274383cfccd01bef6e12db3a1e 332 SUPERFAMILY SSF50129 7 147 3.65E-29 T 28-03-2018 IPR011032 GroES-like A21D_RS04200 ef58273387f9ee5752ac0acd7e9cb0a7 713 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 344 712 1.6E-128 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 A21D_RS04200 ef58273387f9ee5752ac0acd7e9cb0a7 713 SUPERFAMILY SSF53756 457 712 8.48E-15 T 28-03-2018 A21D_RS09430 2a26963af4898b3587d8e9e673a087fe 212 Gene3D G3DSA:1.10.3100.10 1 166 1.2E-11 T 28-03-2018 IPR027910 YdiL-like domain A21D_RS09430 2a26963af4898b3587d8e9e673a087fe 212 Pfam PF01381 Helix-turn-helix 15 63 8.3E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS09430 2a26963af4898b3587d8e9e673a087fe 212 SMART SM00530 10 65 5.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS09430 2a26963af4898b3587d8e9e673a087fe 212 SUPERFAMILY SSF47413 3 66 2.56E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS09430 2a26963af4898b3587d8e9e673a087fe 212 Pfam PF06803 Protein of unknown function (DUF1232) 167 200 3.7E-9 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.6E-174 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 5.0E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 SUPERFAMILY SSF52283 1 136 2.13E-66 T 28-03-2018 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 SUPERFAMILY SSF52283 305 359 2.13E-66 T 28-03-2018 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 SMART SM01002 148 297 1.9E-85 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 SUPERFAMILY SSF51735 136 303 2.46E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 SMART SM01003 4 136 1.2E-74 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 6.4E-81 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 Gene3D G3DSA:3.40.50.720 1 185 1.6E-41 T 28-03-2018 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 Gene3D G3DSA:3.40.50.720 186 371 2.9E-39 T 28-03-2018 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 A21D_RS14465 f3752ebe93539af1adff73e39434d58f 372 PIRSF PIRSF000183 1 371 1.1E-185 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A21D_RS01655 1394be4f7caec18c0e64b4b0beedbc60 286 Gene3D G3DSA:3.30.420.40 115 286 3.5E-39 T 28-03-2018 A21D_RS01655 1394be4f7caec18c0e64b4b0beedbc60 286 Pfam PF00480 ROK family 4 282 1.8E-73 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS01655 1394be4f7caec18c0e64b4b0beedbc60 286 Gene3D G3DSA:3.30.420.40 2 114 7.4E-21 T 28-03-2018 A21D_RS01655 1394be4f7caec18c0e64b4b0beedbc60 286 ProSitePatterns PS01125 ROK family signature. 129 154 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS01655 1394be4f7caec18c0e64b4b0beedbc60 286 SUPERFAMILY SSF53067 1 282 7.78E-48 T 28-03-2018 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 Gene3D G3DSA:1.10.10.60 12 80 4.8E-17 T 28-03-2018 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 SUPERFAMILY SSF46689 16 81 1.18E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 SUPERFAMILY SSF48498 100 214 4.15E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 Gene3D G3DSA:1.10.357.10 81 216 7.4E-13 T 28-03-2018 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 3.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 8.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04915 c5f3ef548828e5c76c0abefab472168f 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 8.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS13825 f46a919b987dda021a36c93b9cf0a65d 231 Gene3D G3DSA:3.20.20.70 1 228 1.3E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS13825 f46a919b987dda021a36c93b9cf0a65d 231 Pfam PF00290 Tryptophan synthase alpha chain 4 219 4.6E-34 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS13825 f46a919b987dda021a36c93b9cf0a65d 231 SUPERFAMILY SSF51366 3 227 1.22E-44 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 SUPERFAMILY SSF56601 46 297 2.49E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 ProSitePatterns PS00146 Beta-lactamase class-A active site. 78 93 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 116 141 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 178 203 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 45 69 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 152 176 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 214 229 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 231 246 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 PRINTS PR00118 Beta-lactamase class A signature 76 93 1.3E-56 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 Pfam PF13354 Beta-lactamase enzyme family 65 271 3.3E-33 T 28-03-2018 A21D_RS09990 2618bb6d47dbf1a0bfa11bcb34b88909 299 Gene3D G3DSA:3.40.710.10 43 297 1.1E-25 T 28-03-2018 A21D_RS10550 86d41b661b12c7f52d087e1de82ca05d 200 Gene3D G3DSA:1.10.443.10 18 200 8.2E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS10550 86d41b661b12c7f52d087e1de82ca05d 200 SUPERFAMILY SSF56349 14 199 1.24E-30 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS10550 86d41b661b12c7f52d087e1de82ca05d 200 Pfam PF00589 Phage integrase family 20 199 1.8E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 237 1.7E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 SUPERFAMILY SSF47203 253 414 1.01E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Gene3D G3DSA:2.40.110.10 144 237 5.7E-35 T 28-03-2018 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 408 1.1E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Gene3D G3DSA:1.20.140.10 238 421 1.2E-54 T 28-03-2018 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 141 4.6E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 Gene3D G3DSA:1.10.540.10 3 143 2.6E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 368 387 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS12625 a3019e05a876021fbd1baab6c90b79ea 554 SUPERFAMILY SSF56645 28 260 5.1E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 ProSitePatterns PS01125 ROK family signature. 215 242 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 Gene3D G3DSA:1.10.10.10 8 74 4.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 Gene3D G3DSA:3.30.420.40 75 200 3.5E-27 T 28-03-2018 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 SUPERFAMILY SSF53067 81 388 9.21E-61 T 28-03-2018 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 Pfam PF12802 MarR family 17 59 2.4E-6 T 28-03-2018 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 SUPERFAMILY SSF46785 8 73 2.15E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 Pfam PF00480 ROK family 83 384 3.1E-69 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS04130 a8224fb76cdf387d65b4a0943d09f694 394 Gene3D G3DSA:3.30.420.40 201 394 6.0E-57 T 28-03-2018 A21D_RS17925 0b42d7b6b9cde7979d2f4ecd94403c09 148 Pfam PF02050 Flagellar FliJ protein 20 142 6.2E-14 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A21D_RS17925 0b42d7b6b9cde7979d2f4ecd94403c09 148 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 7 143 1.6E-25 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A21D_RS02875 e0dbee043db9f2048366d15ee53d4436 235 SUPERFAMILY SSF88713 15 231 1.64E-62 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS02875 e0dbee043db9f2048366d15ee53d4436 235 Pfam PF01522 Polysaccharide deacetylase 44 160 1.5E-29 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS02875 e0dbee043db9f2048366d15ee53d4436 235 Gene3D G3DSA:3.20.20.370 17 235 4.5E-59 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 Gene3D G3DSA:3.50.50.60 3 127 8.4E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 Gene3D G3DSA:3.50.50.60 239 316 2.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 2.2E-37 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.2E-37 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.2E-37 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.2E-37 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 2.2E-37 T 28-03-2018 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 Gene3D G3DSA:3.50.50.60 128 238 4.6E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.7E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 1.6E-118 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 SUPERFAMILY SSF51905 6 304 5.71E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS00670 cc93789d3146bd13c7e69dfea2a026a3 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 2.8E-68 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 154 6.8E-35 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 Gene3D G3DSA:3.40.980.10 3 165 1.4E-31 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 Pfam PF00994 Probable molybdopterin binding domain 16 158 7.4E-32 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 SMART SM00852 16 159 4.5E-24 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 SUPERFAMILY SSF53218 10 160 4.45E-39 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A21D_RS09275 3c6655c14802fea1d3773074a19b40a7 170 PIRSF PIRSF006443 2 167 8.4E-61 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A21D_RS11645 1ea744d2e35fb4270c54fbc369c4497b 259 Pfam PF12679 ABC-2 family transporter protein 5 252 2.8E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 Pfam PF01261 Xylose isomerase-like TIM barrel 22 237 5.3E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 Gene3D G3DSA:3.20.20.150 1 297 6.1E-59 T 28-03-2018 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 SMART SM00518 3 285 2.0E-130 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 43.345 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 9.3E-104 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A21D_RS15790 56e48c77faf0e2c608f6ad200464443e 297 SUPERFAMILY SSF51658 2 294 4.98E-104 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS07075 7a44240f373935a4904c0e46acbc566b 236 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 57 225 3.6E-53 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS07075 7a44240f373935a4904c0e46acbc566b 236 SMART SM00646 116 225 6.1E-38 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS07075 7a44240f373935a4904c0e46acbc566b 236 SUPERFAMILY SSF53187 55 228 7.85E-55 T 28-03-2018 A21D_RS07075 7a44240f373935a4904c0e46acbc566b 236 Gene3D G3DSA:3.40.630.40 36 235 2.9E-60 T 28-03-2018 A21D_RS08230 a52d88dd347ab9989e2c7fa695456087 372 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 2 366 1.2E-143 T 28-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 A21D_RS08230 a52d88dd347ab9989e2c7fa695456087 372 PIRSF PIRSF007313 1 372 7.5E-147 T 28-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 A21D_RS15370 855d1eb7947b3cd8d00daaebadbbe246 226 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 108 6.9E-45 T 28-03-2018 IPR014243 Transcription factor, RsfA A21D_RS15370 855d1eb7947b3cd8d00daaebadbbe246 226 Gene3D G3DSA:1.10.10.60 1 119 1.5E-6 T 28-03-2018 A21D_RS15370 855d1eb7947b3cd8d00daaebadbbe246 226 Gene3D G3DSA:1.20.5.170 130 192 7.0E-5 T 28-03-2018 A21D_RS07150 e216fe021241a37b33c03d5fa1518f74 272 Pfam PF03180 NLPA lipoprotein 29 263 2.2E-78 T 28-03-2018 IPR004872 Lipoprotein NlpA family A21D_RS07150 e216fe021241a37b33c03d5fa1518f74 272 Gene3D G3DSA:3.40.190.10 119 264 1.0E-41 T 28-03-2018 A21D_RS07150 e216fe021241a37b33c03d5fa1518f74 272 PIRSF PIRSF002854 1 265 2.1E-82 T 28-03-2018 IPR004872 Lipoprotein NlpA family A21D_RS07150 e216fe021241a37b33c03d5fa1518f74 272 SUPERFAMILY SSF53850 28 264 4.8E-75 T 28-03-2018 A21D_RS07150 e216fe021241a37b33c03d5fa1518f74 272 Gene3D G3DSA:3.40.190.10 28 118 1.8E-20 T 28-03-2018 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 SMART SM00228 83 159 1.9E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 Gene3D G3DSA:2.30.42.10 86 190 4.6E-14 T 28-03-2018 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 39 387 1.4E-155 T 28-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 Pfam PF05580 SpoIVB peptidase S55 175 382 3.2E-86 T 28-03-2018 IPR008763 Peptidase S55, SpoIVB A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 Gene3D G3DSA:2.40.10.10 232 392 3.4E-4 T 28-03-2018 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 SUPERFAMILY SSF50156 83 168 4.34E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 Pfam PF13180 PDZ domain 93 166 5.7E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS16150 5f94c91eed449c03ef8ee13112f3e75f 398 SUPERFAMILY SSF50494 315 380 5.74E-6 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 SUPERFAMILY SSF51366 5 253 3.48E-81 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 12 247 4.0E-74 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 50 63 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 Pfam PF00290 Tryptophan synthase alpha chain 11 248 1.1E-84 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 Gene3D G3DSA:3.20.20.70 4 251 2.4E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03250 45daa3ec279712fa732a85bc9eece0b7 257 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 16 257 31.666 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 5.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 Gene3D G3DSA:1.10.10.10 120 231 4.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 SMART SM00448 2 112 5.7E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 SUPERFAMILY SSF52172 3 118 2.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 Gene3D G3DSA:3.40.50.2300 1 119 1.9E-28 T 28-03-2018 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 Pfam PF00072 Response regulator receiver domain 4 112 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 SUPERFAMILY SSF46894 130 226 1.13E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS11745 42fdbca9c074e64d2b92cebf017d2cdd 232 SMART SM00862 151 225 6.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Gene3D G3DSA:3.40.50.720 3 202 8.8E-41 T 28-03-2018 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Gene3D G3DSA:1.20.5.170 206 228 1.2E-10 T 28-03-2018 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 13 185 5.8E-37 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 13 417 5.4E-117 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 SMART SM00984 322 424 1.3E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 SUPERFAMILY SSF48179 206 297 4.59E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 SUPERFAMILY SSF52413 307 435 4.58E-26 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 423 1.9E-21 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Gene3D G3DSA:3.40.50.720 229 436 7.2E-57 T 28-03-2018 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 SUPERFAMILY SSF51735 13 192 3.07E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 3.4E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 PIRSF PIRSF000124 12 437 5.9E-62 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS02605 abdf0c599cee32cedcc8a94819f05f80 437 PIRSF PIRSF500136 2 437 1.5E-155 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A21D_RS03610 466a597a118301a663cb6c3bc83ebd4b 234 Hamap MF_02104 Lactate utilization protein C [lutC]. 2 232 48.004 T 28-03-2018 IPR022823 Lactate utilization protein C A21D_RS03610 466a597a118301a663cb6c3bc83ebd4b 234 SUPERFAMILY SSF100950 44 233 5.44E-40 T 28-03-2018 A21D_RS03610 466a597a118301a663cb6c3bc83ebd4b 234 Gene3D G3DSA:3.40.50.10420 42 233 1.1E-39 T 28-03-2018 A21D_RS03610 466a597a118301a663cb6c3bc83ebd4b 234 Pfam PF02589 LUD domain 51 232 4.1E-33 T 28-03-2018 IPR003741 LUD domain A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Gene3D G3DSA:3.30.1490.100 254 364 3.8E-26 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Gene3D G3DSA:3.30.70.270 50 126 4.0E-25 T 28-03-2018 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Gene3D G3DSA:3.30.70.270 127 177 1.2E-16 T 28-03-2018 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 SUPERFAMILY SSF100879 250 347 5.65E-24 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Pfam PF00817 impB/mucB/samB family 15 162 4.7E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 SUPERFAMILY SSF56672 7 242 3.2E-84 T 28-03-2018 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Gene3D G3DSA:1.10.150.20 178 253 7.7E-20 T 28-03-2018 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Pfam PF11798 IMS family HHH motif 176 205 5.1E-8 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Pfam PF11799 impB/mucB/samB family C-terminal domain 251 354 3.5E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A21D_RS16245 0ff38a12f587fb3a7400a4fb088ad6b4 420 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 38.582 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Pfam PF00874 PRD domain 187 272 2.7E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Pfam PF00874 PRD domain 294 381 1.3E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:3.40.50.2300 392 480 2.1E-19 T 28-03-2018 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 SUPERFAMILY SSF63520 179 272 5.75E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 SUPERFAMILY SSF63520 287 385 4.71E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 SUPERFAMILY SSF55804 493 634 3.79E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 SUPERFAMILY SSF52794 394 474 1.67E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:1.10.1790.10 275 386 1.9E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:1.10.1790.10 155 274 4.6E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:1.10.10.10 83 149 3.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:1.10.10.10 1 68 6.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 540 556 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Pfam PF08279 HTH domain 4 43 7.5E-7 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Gene3D G3DSA:3.40.930.10 491 635 1.8E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12430 a44114c3498a9c235b610fffe76ae048 636 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 496 633 1.0E-26 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS07915 d0981e890b62287f4016b92597e15fee 205 Gene3D G3DSA:3.90.850.10 1 205 1.6E-50 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS07915 d0981e890b62287f4016b92597e15fee 205 SUPERFAMILY SSF56529 4 195 1.44E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS07915 d0981e890b62287f4016b92597e15fee 205 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 5 199 3.0E-35 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 Pfam PF00871 Acetokinase family 5 310 3.7E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 PIRSF PIRSF036458 1 356 2.7E-127 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 SUPERFAMILY SSF53067 177 355 2.44E-40 T 28-03-2018 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 SUPERFAMILY SSF53067 4 172 7.34E-56 T 28-03-2018 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 PRINTS PR00471 Acetate kinase family signature 5 16 2.9E-16 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 PRINTS PR00471 Acetate kinase family signature 297 313 2.9E-16 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 PRINTS PR00471 Acetate kinase family signature 183 204 2.9E-16 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 PRINTS PR00471 Acetate kinase family signature 274 287 2.9E-16 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 353 4.7E-126 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 Gene3D G3DSA:3.30.420.40 184 361 4.1E-40 T 28-03-2018 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 Hamap MF_00542 Probable butyrate kinase [buk]. 1 365 127.903 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 183 200 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS05910 9651ec945ee10be72a8a9d5db2a1b264 365 Gene3D G3DSA:3.30.420.40 2 183 4.6E-44 T 28-03-2018 A21D_RS03070 d20e3eab3904edb954e5bb5eb6fbf54b 320 SUPERFAMILY SSF53807 42 311 9.81E-69 T 28-03-2018 A21D_RS03070 d20e3eab3904edb954e5bb5eb6fbf54b 320 Gene3D G3DSA:3.40.50.1980 30 159 2.8E-30 T 28-03-2018 A21D_RS03070 d20e3eab3904edb954e5bb5eb6fbf54b 320 Gene3D G3DSA:3.40.50.1980 160 320 1.2E-34 T 28-03-2018 A21D_RS03070 d20e3eab3904edb954e5bb5eb6fbf54b 320 Pfam PF01497 Periplasmic binding protein 62 296 4.5E-30 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS19585 9a6d31db2d7edaafa7b27a2c49139fac 159 Pfam PF12867 DinB superfamily 10 143 9.0E-12 T 28-03-2018 IPR024775 DinB-like domain A21D_RS19585 9a6d31db2d7edaafa7b27a2c49139fac 159 Gene3D G3DSA:1.20.120.450 1 152 1.1E-16 T 28-03-2018 A21D_RS19585 9a6d31db2d7edaafa7b27a2c49139fac 159 SUPERFAMILY SSF109854 8 159 1.34E-28 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 SMART SM00345 13 68 1.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 Gene3D G3DSA:1.10.10.10 2 70 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 66 2.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09755 eb56eb92eca006fc1e41b346517beda0 77 SUPERFAMILY SSF46785 3 65 5.65E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12055 e78f74089e158bbe547e33ba22f5e0c8 67 Pfam PF02597 ThiS family 7 67 3.8E-12 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A21D_RS12055 e78f74089e158bbe547e33ba22f5e0c8 67 Gene3D G3DSA:3.10.20.30 1 67 1.6E-18 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS12055 e78f74089e158bbe547e33ba22f5e0c8 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 7.0E-21 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis A21D_RS12055 e78f74089e158bbe547e33ba22f5e0c8 67 SUPERFAMILY SSF54285 3 66 1.74E-18 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A21D_RS10535 63f54dff9d68a88fcbe4476f3bc9e2d5 104 Pfam PF08863 YolD-like protein 14 101 1.4E-24 T 28-03-2018 IPR014962 YolD-like protein A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 SUPERFAMILY SSF51569 1 211 1.15E-76 T 28-03-2018 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 Hamap MF_00494 Probable transaldolase [tal]. 1 213 46.129 T 28-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 Gene3D G3DSA:3.20.20.70 1 213 8.2E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 2.8E-101 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS04685 b8d83bd696f80a05a7361d37cebd55f2 213 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 204 1.7E-56 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 SUPERFAMILY SSF75217 72 248 1.4E-54 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 SUPERFAMILY SSF88697 2 68 1.27E-14 T 28-03-2018 IPR015947 PUA-like domain A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 12 249 2.9E-63 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 Gene3D G3DSA:3.40.1280.10 1 252 2.2E-79 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 PIRSF PIRSF015601 1 249 1.2E-66 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS15655 cb33a0560b95f2015397dcb7f096833a 252 Pfam PF04452 RNA methyltransferase 17 244 7.0E-74 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A21D_RS03285 e90640578fb63893f499dbc8b9d44ce0 131 SMART SM00345 15 74 2.4E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03285 e90640578fb63893f499dbc8b9d44ce0 131 Gene3D G3DSA:1.10.10.10 7 70 2.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03285 e90640578fb63893f499dbc8b9d44ce0 131 SUPERFAMILY SSF46785 4 78 4.01E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03285 e90640578fb63893f499dbc8b9d44ce0 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 67 7.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09670 1475c92ebfb2ea374bb536130280730b 103 SUPERFAMILY SSF161219 5 90 1.7E-18 T 28-03-2018 A21D_RS09670 1475c92ebfb2ea374bb536130280730b 103 Gene3D G3DSA:3.30.40.10 54 102 3.7E-5 T 28-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type A21D_RS09670 1475c92ebfb2ea374bb536130280730b 103 Pfam PF05495 CHY zinc finger 15 87 6.9E-12 T 28-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 A21D_RS09670 1475c92ebfb2ea374bb536130280730b 103 PIRSF PIRSF017292 1 103 1.2E-41 T 28-03-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 321 3.6E-93 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 Gene3D G3DSA:3.90.650.10 144 321 4.1E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 296 2.2E-7 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 SUPERFAMILY SSF56042 142 298 4.78E-27 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 Gene3D G3DSA:3.30.1330.10 1 141 1.1E-33 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 137 3.3E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 318 28.227 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 PIRSF PIRSF005303 1 321 2.0E-92 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A21D_RS10170 ca47af9ab09fcd6ae8648cb8327c6c04 322 SUPERFAMILY SSF55326 10 138 2.09E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A21D_RS18455 82df5c8227b6eea289c57e4eae7a9e96 57 Pfam PF01783 Ribosomal L32p protein family 2 56 1.9E-26 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18455 82df5c8227b6eea289c57e4eae7a9e96 57 SUPERFAMILY SSF57829 1 55 1.46E-21 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A21D_RS18455 82df5c8227b6eea289c57e4eae7a9e96 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 19.743 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18455 82df5c8227b6eea289c57e4eae7a9e96 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 5.5E-26 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 4.1E-31 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 Pfam PF00375 Sodium:dicarboxylate symporter family 13 400 1.1E-103 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 Gene3D G3DSA:1.10.3860.10 1 407 2.7E-112 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18985 cee4dc15e3eee9197985a26fb3d5bc46 407 SUPERFAMILY SSF118215 12 402 6.8E-102 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS12115 55f4037103194e92b099e7bb01b4638e 149 Pfam PF06146 Phosphate-starvation-inducible E 61 126 4.3E-17 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like A21D_RS12115 55f4037103194e92b099e7bb01b4638e 149 PIRSF PIRSF029598 1 143 6.3E-41 T 28-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 A21D_RS08830 895194c0595a91ad6514be2c2a273048 220 SMART SM00382 27 219 2.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08830 895194c0595a91ad6514be2c2a273048 220 SUPERFAMILY SSF52540 2 213 2.04E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08830 895194c0595a91ad6514be2c2a273048 220 Pfam PF00005 ABC transporter 19 163 8.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08830 895194c0595a91ad6514be2c2a273048 220 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08830 895194c0595a91ad6514be2c2a273048 220 Gene3D G3DSA:3.40.50.300 1 220 6.9E-55 T 28-03-2018 A21D_RS17450 3a486c844ac0ebaa889c6b2e210a5b75 85 Gene3D G3DSA:1.10.10.60 6 29 5.1E-6 T 28-03-2018 A21D_RS17450 3a486c844ac0ebaa889c6b2e210a5b75 85 SUPERFAMILY SSF47413 6 71 3.16E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS17450 3a486c844ac0ebaa889c6b2e210a5b75 85 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 57 1.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS17450 3a486c844ac0ebaa889c6b2e210a5b75 85 Gene3D G3DSA:1.10.260.40 30 75 9.0E-5 T 28-03-2018 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 SMART SM00448 3 115 1.9E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 Gene3D G3DSA:3.40.50.2300 2 125 1.1E-32 T 28-03-2018 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 SUPERFAMILY SSF46894 126 225 1.25E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 Gene3D G3DSA:1.10.10.10 126 229 1.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 SMART SM00862 147 224 3.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 7.7E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 Pfam PF00072 Response regulator receiver domain 5 115 3.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS08375 fe490dcd847418793769d3ac6b70c217 229 SUPERFAMILY SSF52172 2 128 6.12E-38 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 SUPERFAMILY SSF55681 93 341 3.73E-80 T 28-03-2018 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 340 4.2E-105 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 341 5.1E-110 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 1.7E-21 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 SUPERFAMILY SSF46589 13 100 1.67E-20 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 47.358 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A21D_RS14745 7b18a7fdc744d1ddebf4964c45081e40 344 Gene3D G3DSA:3.30.930.10 8 344 2.1E-90 T 28-03-2018 A21D_RS13920 e729b1ffba0854cabf68cd123fb47063 74 Gene3D G3DSA:3.30.300.130 1 74 2.0E-26 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS13920 e729b1ffba0854cabf68cd123fb47063 74 Pfam PF01106 NifU-like domain 5 71 2.2E-26 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A21D_RS13920 e729b1ffba0854cabf68cd123fb47063 74 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 9 73 4.0E-29 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A21D_RS13920 e729b1ffba0854cabf68cd123fb47063 74 SUPERFAMILY SSF117916 2 73 1.08E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS12610 332e731d9f631b58b81e289f85327b8f 275 Pfam PF13350 Tyrosine phosphatase family 30 273 9.0E-68 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type A21D_RS12610 332e731d9f631b58b81e289f85327b8f 275 Gene3D G3DSA:3.90.190.10 44 221 8.8E-23 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like A21D_RS12610 332e731d9f631b58b81e289f85327b8f 275 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 168 178 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A21D_RS12610 332e731d9f631b58b81e289f85327b8f 275 SUPERFAMILY SSF52799 30 273 5.71E-49 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like A21D_RS06505 461432bbdc132ad3ccbbd06e670ea18c 405 Pfam PF01610 Transposase 151 391 3.6E-66 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain A21D_RS06505 461432bbdc132ad3ccbbd06e670ea18c 405 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 35 80 3.9E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger A21D_RS06505 461432bbdc132ad3ccbbd06e670ea18c 405 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 136 5.4E-11 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain A21D_RS06505 461432bbdc132ad3ccbbd06e670ea18c 405 Gene3D G3DSA:1.10.10.60 104 140 0.0013 T 28-03-2018 A21D_RS06505 461432bbdc132ad3ccbbd06e670ea18c 405 Gene3D G3DSA:2.60.260.40 25 103 7.7E-4 T 28-03-2018 A21D_RS12295 73f3fda6a5a133dd2947becff76295eb 241 Gene3D G3DSA:3.40.50.10310 1 241 1.1E-69 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A21D_RS12295 73f3fda6a5a133dd2947becff76295eb 241 SUPERFAMILY SSF102215 1 237 1.16E-69 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A21D_RS12295 73f3fda6a5a133dd2947becff76295eb 241 Pfam PF02633 Creatinine amidohydrolase 9 234 3.7E-61 T 28-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A21D_RS03885 ee76a5afed16a7aa2db0936a36fb31f8 155 Pfam PF06271 RDD family 19 147 2.8E-29 T 28-03-2018 IPR010432 RDD A21D_RS08300 5f789b3ed5dd409640f5c3a1836c6371 297 SUPERFAMILY SSF81345 6 269 2.62E-30 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS08300 5f789b3ed5dd409640f5c3a1836c6371 297 Pfam PF00950 ABC 3 transport family 3 273 3.3E-47 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A21D_RS08300 5f789b3ed5dd409640f5c3a1836c6371 297 Gene3D G3DSA:1.10.3470.10 1 281 6.8E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS15220 3af382ec5b146f288bf5c0455b133b01 109 SUPERFAMILY SSF118010 1 107 1.14E-29 T 28-03-2018 IPR007422 Cysteine protease Prp A21D_RS15220 3af382ec5b146f288bf5c0455b133b01 109 Pfam PF04327 Cysteine protease Prp 1 104 4.1E-24 T 28-03-2018 IPR007422 Cysteine protease Prp A21D_RS15220 3af382ec5b146f288bf5c0455b133b01 109 Gene3D G3DSA:3.30.70.1490 2 109 1.9E-31 T 28-03-2018 IPR007422 Cysteine protease Prp A21D_RS16980 b8f03acb25ff592362c6221ae398beb4 140 Gene3D G3DSA:3.40.50.850 1 121 4.2E-20 T 28-03-2018 A21D_RS16980 b8f03acb25ff592362c6221ae398beb4 140 Pfam PF00857 Isochorismatase family 16 101 1.1E-16 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS16980 b8f03acb25ff592362c6221ae398beb4 140 SUPERFAMILY SSF52499 3 132 3.14E-24 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS07400 4b0eb261e740a6aa88865c7533bb7ca9 260 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 9.1E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07400 4b0eb261e740a6aa88865c7533bb7ca9 260 SUPERFAMILY SSF56281 1 229 2.49E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07400 4b0eb261e740a6aa88865c7533bb7ca9 260 SMART SM00849 13 191 3.9E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07400 4b0eb261e740a6aa88865c7533bb7ca9 260 Gene3D G3DSA:3.60.15.10 9 251 3.2E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS09465 4fd991c7eef6cdd8b4fde9fb74561e07 177 Gene3D G3DSA:2.60.120.460 1 175 6.3E-42 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS09465 4fd991c7eef6cdd8b4fde9fb74561e07 177 SUPERFAMILY SSF111038 5 95 7.85E-26 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS09465 4fd991c7eef6cdd8b4fde9fb74561e07 177 SUPERFAMILY SSF111038 124 176 7.85E-26 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS09465 4fd991c7eef6cdd8b4fde9fb74561e07 177 Pfam PF01894 Uncharacterised protein family UPF0047 21 174 1.6E-34 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS12645 cef23b99cfd015cd9ec97eb994b68765 261 Gene3D G3DSA:1.10.12.10 222 259 5.6E-18 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS12645 cef23b99cfd015cd9ec97eb994b68765 261 SUPERFAMILY SSF52096 1 261 1.77E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS12645 cef23b99cfd015cd9ec97eb994b68765 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS12645 cef23b99cfd015cd9ec97eb994b68765 261 Gene3D G3DSA:3.90.226.10 2 221 2.6E-65 T 28-03-2018 A21D_RS12645 cef23b99cfd015cd9ec97eb994b68765 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 1.5E-59 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 PIRSF PIRSF002599 1 66 1.8E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 PRINTS PR00050 Cold shock protein signature 24 33 1.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 PRINTS PR00050 Cold shock protein signature 39 57 1.1E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site A21D_RS16835 4278205807b9a054396021f912d0ea48 66 Gene3D G3DSA:2.40.50.140 1 66 3.3E-28 T 28-03-2018 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.8E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A21D_RS16835 4278205807b9a054396021f912d0ea48 66 SUPERFAMILY SSF50249 1 64 7.62E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS16835 4278205807b9a054396021f912d0ea48 66 SMART SM00357 3 66 5.0E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A21D_RS12150 2d6ed18ec77194505698355ba6444b2f 393 SUPERFAMILY SSF53383 5 383 1.36E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS12150 2d6ed18ec77194505698355ba6444b2f 393 Pfam PF00155 Aminotransferase class I and II 33 381 8.4E-59 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS12150 2d6ed18ec77194505698355ba6444b2f 393 Gene3D G3DSA:3.90.1150.10 295 385 2.4E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS12150 2d6ed18ec77194505698355ba6444b2f 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A21D_RS12150 2d6ed18ec77194505698355ba6444b2f 393 Gene3D G3DSA:3.40.640.10 48 294 6.1E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS10830 67ca0508be3b4b90f6b35d27c7895755 513 PIRSF PIRSF005690 19 513 1.0E-180 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS10830 67ca0508be3b4b90f6b35d27c7895755 513 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 34 498 4.7E-186 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 SMART SM00382 100 302 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 444 35.525 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Gene3D G3DSA:1.10.260.30 328 432 1.5E-40 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 1.7E-191 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 SUPERFAMILY SSF52540 43 355 1.06E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Pfam PF02978 Signal peptide binding domain 329 427 5.1E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 SUPERFAMILY SSF47446 329 430 1.55E-38 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 SMART SM00963 2 87 1.4E-34 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Gene3D G3DSA:3.40.50.300 238 319 0.003 T 28-03-2018 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Gene3D G3DSA:3.40.50.300 96 237 6.3E-37 T 28-03-2018 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Gene3D G3DSA:1.20.120.140 1 92 5.1E-31 T 28-03-2018 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.1E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 8.9E-80 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18065 43d38b3d4aaaf357dc5a6fa9c594b752 448 SMART SM00962 101 297 7.9E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 Gene3D G3DSA:3.30.1020.10 163 219 1.8E-24 T 28-03-2018 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 166 203 3.5E-15 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 Gene3D G3DSA:3.40.30.10 1 162 1.9E-43 T 28-03-2018 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 Hamap MF_00401 Peroxiredoxin. 14 219 44.65 T 28-03-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 PIRSF PIRSF000239 9 219 2.5E-77 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 SUPERFAMILY SSF52833 12 219 6.53E-71 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS07420 17881ecafd46d0d4533da4f94f0739ba 220 Pfam PF00578 AhpC/TSA family 16 145 4.9E-36 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS04370 c73acf691bf3ea0fbc44dbc351d99e42 101 SUPERFAMILY SSF52794 1 100 3.14E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS04370 c73acf691bf3ea0fbc44dbc351d99e42 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 94 4.1E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS04370 c73acf691bf3ea0fbc44dbc351d99e42 101 Gene3D G3DSA:3.40.50.2300 1 101 4.0E-37 T 28-03-2018 A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 SMART SM00448 2 115 5.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 Gene3D G3DSA:3.40.50.2300 1 139 2.5E-32 T 28-03-2018 A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 Gene3D G3DSA:1.10.10.10 155 234 2.9E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 PIRSF PIRSF006171 1 229 1.1E-78 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 Pfam PF00072 Response regulator receiver domain 4 114 3.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS08205 229455a1632ac1ac25f3fb57e902777d 238 SUPERFAMILY SSF52172 1 136 2.56E-35 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Pfam PF13091 PLD-like domain 321 447 1.9E-29 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Pfam PF13091 PLD-like domain 134 277 3.8E-16 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Gene3D G3DSA:3.30.870.10 310 464 2.9E-32 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 SUPERFAMILY SSF56024 269 466 1.01E-52 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Hamap MF_01916 Cardiolipin synthase. 9 480 44.247 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 SMART SM00155 393 420 7.4E-7 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 SMART SM00155 217 244 2.9E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 5 480 1.2E-189 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 SUPERFAMILY SSF56024 94 310 4.71E-59 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Gene3D G3DSA:3.30.870.10 108 308 5.3E-40 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 55 9.2E-13 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 PIRSF PIRSF000850 97 276 0.059 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 PIRSF PIRSF000850 305 375 0.65 T 28-03-2018 A21D_RS09100 3a9c3b107b1124a9f376912d280aada2 480 PIRSF PIRSF000850 387 477 0.034 T 28-03-2018 A21D_RS09005 706663f33373ce6c8ceaa645dd95c299 208 Pfam PF13702 Lysozyme-like 48 201 1.7E-51 T 28-03-2018 A21D_RS09005 706663f33373ce6c8ceaa645dd95c299 208 SUPERFAMILY SSF53955 54 202 1.43E-15 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS09005 706663f33373ce6c8ceaa645dd95c299 208 Gene3D G3DSA:1.10.530.10 47 205 2.5E-17 T 28-03-2018 A21D_RS03050 163a50bc145158f620b5321bd1d16a85 255 Pfam PF00977 Histidine biosynthesis protein 5 234 2.3E-86 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A21D_RS03050 163a50bc145158f620b5321bd1d16a85 255 SUPERFAMILY SSF51366 1 251 7.85E-82 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS03050 163a50bc145158f620b5321bd1d16a85 255 Gene3D G3DSA:3.20.20.70 4 247 4.7E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03050 163a50bc145158f620b5321bd1d16a85 255 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 1.2E-113 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A21D_RS03050 163a50bc145158f620b5321bd1d16a85 255 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 47.622 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A21D_RS04755 a06841f5a26c77c154f154d27a94bbed 148 SUPERFAMILY SSF50814 3 144 2.44E-25 T 28-03-2018 IPR012674 Calycin A21D_RS04755 a06841f5a26c77c154f154d27a94bbed 148 Gene3D G3DSA:2.40.128.20 1 148 5.1E-32 T 28-03-2018 IPR012674 Calycin A21D_RS04755 a06841f5a26c77c154f154d27a94bbed 148 Pfam PF09148 Domain of unknown function (DUF1934) 12 139 1.7E-23 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 A21D_RS03365 e5819eb204377c6041c9e0f91e38031c 480 Pfam PF00474 Sodium:solute symporter family 37 432 9.0E-102 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS03365 e5819eb204377c6041c9e0f91e38031c 480 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 472 3.8E-220 T 28-03-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0031402|GO:0071436 A21D_RS03365 e5819eb204377c6041c9e0f91e38031c 480 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS03365 e5819eb204377c6041c9e0f91e38031c 480 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 432 2.8E-91 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS03365 e5819eb204377c6041c9e0f91e38031c 480 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 156 181 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS10260 093f5940bf92dc0884cbbe1b2dca54c5 88 SMART SM00530 7 63 1.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS10260 093f5940bf92dc0884cbbe1b2dca54c5 88 SUPERFAMILY SSF47413 6 68 6.48E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS10260 093f5940bf92dc0884cbbe1b2dca54c5 88 Pfam PF01381 Helix-turn-helix 8 63 3.9E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS10260 093f5940bf92dc0884cbbe1b2dca54c5 88 Gene3D G3DSA:1.10.260.40 5 88 3.8E-10 T 28-03-2018 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 SUPERFAMILY SSF50447 5 90 1.45E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 169 2.8E-48 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 Pfam PF01782 RimM N-terminal domain 8 90 1.2E-20 T 28-03-2018 IPR002676 RimM protein GO:0006364 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 Gene3D G3DSA:2.30.30.240 95 164 1.9E-20 T 28-03-2018 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 169 23.981 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 SUPERFAMILY SSF50346 99 169 2.16E-20 T 28-03-2018 IPR011033 PRC-barrel-like A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 Gene3D G3DSA:2.40.30.60 3 94 2.3E-20 T 28-03-2018 IPR002676 RimM protein GO:0006364 A21D_RS18045 516577667b3ffcff3313fa5eb81d0560 171 Pfam PF05239 PRC-barrel domain 97 170 5.4E-15 T 28-03-2018 IPR027275 PRC-barrel domain A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 Gene3D G3DSA:3.30.1020.10 157 183 3.1E-7 T 28-03-2018 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 4.5E-100 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 7.0E-6 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 PIRSF PIRSF000239 1 187 1.0E-48 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 Pfam PF00578 AhpC/TSA family 4 133 1.1E-30 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 Gene3D G3DSA:3.40.30.10 3 156 2.3E-28 T 28-03-2018 A21D_RS09375 165cd9562399cc9af4fda41f8de58e6a 187 SUPERFAMILY SSF52833 1 187 5.36E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS07990 eb5480b01f491372c68f0ed96a088e41 293 SUPERFAMILY SSF53850 20 289 3.26E-63 T 28-03-2018 A21D_RS07990 eb5480b01f491372c68f0ed96a088e41 293 Gene3D G3DSA:3.40.190.10 9 167 3.7E-32 T 28-03-2018 A21D_RS07990 eb5480b01f491372c68f0ed96a088e41 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 20 286 1.6E-56 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS07990 eb5480b01f491372c68f0ed96a088e41 293 Gene3D G3DSA:3.40.190.10 168 290 2.0E-23 T 28-03-2018 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 SUPERFAMILY SSF90123 21 322 3.79E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 Gene3D G3DSA:1.20.1560.10 1 325 1.8E-69 T 28-03-2018 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 SUPERFAMILY SSF52540 330 575 1.7E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 SMART SM00382 362 551 2.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 Gene3D G3DSA:3.40.50.300 334 572 9.5E-71 T 28-03-2018 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 Pfam PF00005 ABC transporter 353 505 4.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03825 0d69be84f819e7c8a9740f4e23e7ccfe 583 Pfam PF00664 ABC transporter transmembrane region 25 292 3.2E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 SUPERFAMILY SSF53901 3 252 7.02E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 2 374 4.3E-132 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 SUPERFAMILY SSF53901 254 374 2.99E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 Gene3D G3DSA:3.40.47.10 259 373 5.9E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 ProSitePatterns PS00737 Thiolases signature 2. 322 338 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 PIRSF PIRSF000429 1 377 4.2E-127 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 Pfam PF00108 Thiolase, N-terminal domain 2 244 1.9E-69 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 Gene3D G3DSA:3.40.47.10 142 258 9.3E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 Gene3D G3DSA:3.40.47.10 1 132 7.1E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS02305 57f98a99db2fb6b3fdb24c260ec33e7c 380 Pfam PF02803 Thiolase, C-terminal domain 254 374 1.8E-38 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS08755 c37e0252ba3b6e20288250afbfaa4c0d 340 SUPERFAMILY SSF51679 10 333 1.2E-79 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A21D_RS08755 c37e0252ba3b6e20288250afbfaa4c0d 340 Gene3D G3DSA:3.20.20.30 15 337 2.2E-73 T 28-03-2018 A21D_RS08755 c37e0252ba3b6e20288250afbfaa4c0d 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 12 333 7.8E-134 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 A21D_RS08755 c37e0252ba3b6e20288250afbfaa4c0d 340 Pfam PF00296 Luciferase-like monooxygenase 25 310 2.7E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A21D_RS02295 0a9b2944d93a6c5fd3674949ee579c3c 116 Gene3D G3DSA:3.10.129.10 1 111 1.2E-12 T 28-03-2018 A21D_RS02295 0a9b2944d93a6c5fd3674949ee579c3c 116 Pfam PF01575 MaoC like domain 3 88 3.6E-12 T 28-03-2018 IPR002539 MaoC-like domain A21D_RS02295 0a9b2944d93a6c5fd3674949ee579c3c 116 SUPERFAMILY SSF54637 5 103 7.46E-14 T 28-03-2018 IPR029069 HotDog domain A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 SUPERFAMILY SSF58104 316 585 1.23E-69 T 28-03-2018 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 SUPERFAMILY SSF58104 254 283 1.23E-69 T 28-03-2018 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 Pfam PF00672 HAMP domain 229 277 7.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 SMART SM00283 310 585 4.6E-71 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 Gene3D G3DSA:1.10.287.950 342 586 1.5E-55 T 28-03-2018 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 Gene3D G3DSA:1.10.287.950 226 341 4.4E-10 T 28-03-2018 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 SMART SM00304 228 281 1.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 437 466 1.1E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 435 1.1E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 27 52 1.1E-19 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS03135 18184301562c21e73d536d32d381d3c2 586 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 371 538 1.9E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS10080 5cecd129519e591feea8b0c60585c437 154 Hamap MF_00745 Protein SprT-like. 7 149 37.999 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like A21D_RS10080 5cecd129519e591feea8b0c60585c437 154 Pfam PF17283 SprT-like zinc ribbon domain 113 147 1.5E-6 T 28-03-2018 IPR035240 SprT-like, zinc ribbon domain A21D_RS10080 5cecd129519e591feea8b0c60585c437 154 SMART SM00731 7 149 5.3E-49 T 28-03-2018 IPR006640 SprT-like A21D_RS10080 5cecd129519e591feea8b0c60585c437 154 Pfam PF10263 SprT-like family 12 100 1.2E-12 T 28-03-2018 IPR006640 SprT-like A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 PRINTS PR00502 NUDIX hydrolase family signature 72 86 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 PRINTS PR00502 NUDIX hydrolase family signature 86 101 4.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 SUPERFAMILY SSF55811 7 178 2.57E-51 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 Gene3D G3DSA:3.90.79.10 3 179 4.2E-44 T 28-03-2018 A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 Pfam PF00293 NUDIX domain 42 156 1.8E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS16290 cc920dc5143a2daaacf1d14d104c0e2f 181 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A21D_RS15705 57e047880321957d5751521ffbae9f76 324 SUPERFAMILY SSF52540 61 279 1.95E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15705 57e047880321957d5751521ffbae9f76 324 Pfam PF02562 PhoH-like protein 113 316 1.2E-96 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 A21D_RS15705 57e047880321957d5751521ffbae9f76 324 Gene3D G3DSA:3.40.50.300 110 316 4.4E-31 T 28-03-2018 A21D_RS02935 f8cab2eba43be87ad71305af04d481bb 182 Pfam PF00857 Isochorismatase family 4 176 2.8E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS02935 f8cab2eba43be87ad71305af04d481bb 182 Gene3D G3DSA:3.40.50.850 1 182 5.4E-48 T 28-03-2018 A21D_RS02935 f8cab2eba43be87ad71305af04d481bb 182 SUPERFAMILY SSF52499 2 181 4.97E-51 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS14615 e8e5626d63135b0bba5830fd3ac6ad0a 201 SUPERFAMILY SSF52540 1 192 5.85E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14615 e8e5626d63135b0bba5830fd3ac6ad0a 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 27.638 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A21D_RS14615 e8e5626d63135b0bba5830fd3ac6ad0a 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 8.2E-64 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A21D_RS14615 e8e5626d63135b0bba5830fd3ac6ad0a 201 Pfam PF01121 Dephospho-CoA kinase 4 182 1.2E-61 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A21D_RS14615 e8e5626d63135b0bba5830fd3ac6ad0a 201 Gene3D G3DSA:3.40.50.300 2 197 3.9E-48 T 28-03-2018 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Pfam PF01588 Putative tRNA binding domain 556 648 3.3E-27 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Pfam PF08264 Anticodon-binding domain of tRNA 394 490 2.4E-8 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 SUPERFAMILY SSF50249 549 648 6.12E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 SUPERFAMILY SSF52374 4 350 5.91E-118 T 28-03-2018 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Gene3D G3DSA:1.10.730.10 348 516 9.2E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Gene3D G3DSA:2.40.50.140 542 651 7.2E-29 T 28-03-2018 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 513 51.43 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Pfam PF09334 tRNA synthetases class I (M) 8 363 8.0E-122 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 528 651 7.9E-45 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 Gene3D G3DSA:3.40.50.620 5 347 4.0E-106 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 SUPERFAMILY SSF47323 353 563 3.18E-44 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 274 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 351 362 7.8E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS06815 c4bbf89e728ec59da6a4498a91c73967 651 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 142 514 1.1E-120 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A21D_RS04245 c9bc9915750378342c25b1addf585c88 271 SUPERFAMILY SSF53474 92 257 1.46E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS04245 c9bc9915750378342c25b1addf585c88 271 Gene3D G3DSA:3.40.50.1820 33 231 1.2E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05565 5406670d2ec87a73fea0ceb1e2f597a0 267 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 75 4.4E-20 T 28-03-2018 IPR002831 Transcription regulator TrmB, N-terminal A21D_RS05565 5406670d2ec87a73fea0ceb1e2f597a0 267 SUPERFAMILY SSF46785 3 94 4.43E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05565 5406670d2ec87a73fea0ceb1e2f597a0 267 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 168 3.4E-5 T 28-03-2018 IPR021586 Transcription regulator TrmB, C-terminal A21D_RS05565 5406670d2ec87a73fea0ceb1e2f597a0 267 Gene3D G3DSA:1.10.10.10 1 102 2.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05130 1b050c25628b86c623aaec60c20a13fa 262 PIRSF PIRSF009141 2 261 3.7E-129 T 28-03-2018 IPR008535 Protein of unknown function DUF817 A21D_RS05130 1b050c25628b86c623aaec60c20a13fa 262 Pfam PF05675 Protein of unknown function (DUF817) 6 240 5.8E-106 T 28-03-2018 IPR008535 Protein of unknown function DUF817 A21D_RS17265 77e96a37adeccdfba06a57198df275c3 1293 Gene3D G3DSA:1.20.120.330 10 217 7.7E-8 T 28-03-2018 A21D_RS17265 77e96a37adeccdfba06a57198df275c3 1293 Pfam PF10145 Phage-related minor tail protein 209 407 5.7E-51 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS17265 77e96a37adeccdfba06a57198df275c3 1293 Gene3D G3DSA:1.20.120.570 636 792 0.14 T 28-03-2018 A21D_RS17265 77e96a37adeccdfba06a57198df275c3 1293 Gene3D G3DSA:1.20.120.20 369 512 4.2E-4 T 28-03-2018 A21D_RS17265 77e96a37adeccdfba06a57198df275c3 1293 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 176 513 7.9E-74 T 28-03-2018 IPR010090 Phage tail tape measure protein A21D_RS08160 eaa7fb3305fb9b40484e38634731bd7c 94 Gene3D G3DSA:1.20.90.10 3 90 4.7E-9 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A21D_RS08160 eaa7fb3305fb9b40484e38634731bd7c 94 SUPERFAMILY SSF48619 8 61 1.05E-8 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A21D_RS16650 48539fc0a1d6ce8351a9e2c318a163c0 190 SMART SM00914 139 175 2.0E-9 T 28-03-2018 IPR014957 IDEAL domain A21D_RS16650 48539fc0a1d6ce8351a9e2c318a163c0 190 PIRSF PIRSF007165 1 182 5.4E-71 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 A21D_RS16650 48539fc0a1d6ce8351a9e2c318a163c0 190 Pfam PF08864 UPF0302 domain 9 112 4.4E-42 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal A21D_RS16650 48539fc0a1d6ce8351a9e2c318a163c0 190 Pfam PF08858 IDEAL domain 139 175 2.1E-10 T 28-03-2018 IPR014957 IDEAL domain A21D_RS16650 48539fc0a1d6ce8351a9e2c318a163c0 190 Hamap MF_00760 UPF0302 protein . 2 178 30.645 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 A21D_RS03580 845dc7611809d48c967fae79fca9c059 205 Pfam PF02581 Thiamine monophosphate synthase 10 192 4.8E-53 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03580 845dc7611809d48c967fae79fca9c059 205 Gene3D G3DSA:3.20.20.70 2 205 5.4E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03580 845dc7611809d48c967fae79fca9c059 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 203 23.667 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03580 845dc7611809d48c967fae79fca9c059 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 204 5.5E-60 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03580 845dc7611809d48c967fae79fca9c059 205 SUPERFAMILY SSF51391 6 205 4.05E-61 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 SUPERFAMILY SSF69189 296 395 1.65E-15 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 Gene3D G3DSA:3.40.710.10 27 304 2.3E-45 T 28-03-2018 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 284 8.2E-76 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 SUPERFAMILY SSF56601 5 304 7.15E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 Gene3D G3DSA:2.60.410.10 305 413 3.6E-19 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 1.2E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 121 138 1.2E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 148 161 1.2E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 SMART SM00936 304 413 2.2E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07180 f1480dd8e1bdc13d4e378b08e0558234 443 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 304 413 2.5E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 SUPERFAMILY SSF63882 7 181 3.4E-52 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 182 319 5.7E-30 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 SUPERFAMILY SSF63867 333 408 1.31E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Pfam PF00994 Probable molybdopterin binding domain 186 321 5.1E-24 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Pfam PF03454 MoeA C-terminal region (domain IV) 337 407 6.2E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Gene3D G3DSA:3.90.105.10 26 61 1.3E-7 T 28-03-2018 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 172 6.1E-42 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Gene3D G3DSA:2.40.340.10 334 409 5.7E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Gene3D G3DSA:3.40.980.10 155 330 1.5E-50 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 Gene3D G3DSA:2.170.190.11 62 146 9.2E-27 T 28-03-2018 A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 SUPERFAMILY SSF53218 182 326 8.77E-37 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS14970 57d7b2721189bf8f8eb43d2438f9049a 418 SMART SM00852 185 323 2.8E-34 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS00260 d57989b0da25eb7125c84a554e8fd3cf 104 Pfam PF00085 Thioredoxin 7 93 1.1E-8 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS00260 d57989b0da25eb7125c84a554e8fd3cf 104 Gene3D G3DSA:3.40.30.10 1 94 1.7E-10 T 28-03-2018 A21D_RS00260 d57989b0da25eb7125c84a554e8fd3cf 104 SUPERFAMILY SSF52833 10 93 1.01E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 Gene3D G3DSA:3.40.50.720 1 165 2.4E-27 T 28-03-2018 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 137 168 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 408 9.6E-47 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 SUPERFAMILY SSF51735 1 164 2.91E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 73 89 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 108 128 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 PRINTS PR00732 Glycosyl hydrolase family 4 signature 163 174 6.9E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 SUPERFAMILY SSF56327 169 432 4.75E-91 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 Gene3D G3DSA:3.90.110.10 167 433 1.0E-84 T 28-03-2018 A21D_RS01085 ad45f575723b0b5ad1cce3b7b484ca4f 433 Pfam PF02056 Family 4 glycosyl hydrolase 2 183 3.0E-68 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 SUPERFAMILY SSF52540 133 447 1.96E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 Gene3D G3DSA:3.40.50.300 112 292 4.3E-20 T 28-03-2018 A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 Gene3D G3DSA:3.40.50.300 314 466 4.5E-20 T 28-03-2018 A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 SMART SM00490 354 435 2.7E-11 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 SMART SM00487 118 301 9.7E-17 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 Pfam PF04851 Type III restriction enzyme, res subunit 122 271 1.2E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A21D_RS00880 538959fd9fa8f6d2069f86a5a6ca5bab 470 Pfam PF00271 Helicase conserved C-terminal domain 319 434 6.0E-14 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 Gene3D G3DSA:3.40.640.10 84 337 1.0E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 Pfam PF02347 Glycine cleavage system P-protein 4 443 1.5E-152 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 Gene3D G3DSA:3.90.1150.10 338 449 2.1E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 49.517 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 PIRSF PIRSF006815 3 448 2.6E-185 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A21D_RS16005 d56c3ddc740b04e11a8f680670b27d6d 449 SUPERFAMILY SSF53383 3 447 4.08E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 SUPERFAMILY SSF48008 95 233 6.8E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 SMART SM00345 15 74 1.1E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.7E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 SUPERFAMILY SSF46785 5 78 3.39E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 Pfam PF07729 FCD domain 99 224 1.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 Gene3D G3DSA:1.20.120.530 87 234 3.9E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 SMART SM00895 99 225 1.5E-18 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS03625 624a00a12a565dcca371f932ef931a98 234 Gene3D G3DSA:1.10.10.10 1 84 3.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13515 ec9c4ebb4941ab1fa1ede03ce7074a3b 268 Hamap MF_00361 NAD kinase [nadK]. 1 263 24.731 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS13515 ec9c4ebb4941ab1fa1ede03ce7074a3b 268 SUPERFAMILY SSF111331 20 261 1.7E-64 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A21D_RS13515 ec9c4ebb4941ab1fa1ede03ce7074a3b 268 Pfam PF01513 ATP-NAD kinase 24 187 9.4E-27 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS13515 ec9c4ebb4941ab1fa1ede03ce7074a3b 268 Gene3D G3DSA:2.60.200.30 124 239 1.7E-23 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS13515 ec9c4ebb4941ab1fa1ede03ce7074a3b 268 Gene3D G3DSA:3.40.50.10330 1 123 1.1E-27 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 SUPERFAMILY SSF46548 10 105 2.56E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Gene3D G3DSA:3.30.70.20 5 33 0.018 T 28-03-2018 A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Gene3D G3DSA:3.30.70.20 34 83 4.5E-10 T 28-03-2018 A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 PIRSF PIRSF000139 5 444 2.0E-138 T 28-03-2018 A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Pfam PF13183 4Fe-4S dicluster domain 22 91 1.3E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Pfam PF02754 Cysteine-rich domain 328 413 2.3E-16 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Pfam PF02754 Cysteine-rich domain 198 280 1.9E-17 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS11325 0522ce494200f1827ffaf9570e6bc4d1 456 Gene3D G3DSA:3.30.70.20 84 408 8.5E-5 T 28-03-2018 A21D_RS00745 49716e6e040907fb6d37a34076d33d86 390 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 24 191 6.8E-28 T 28-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 A21D_RS00745 49716e6e040907fb6d37a34076d33d86 390 SUPERFAMILY SSF53756 104 373 9.81E-22 T 28-03-2018 A21D_RS00745 49716e6e040907fb6d37a34076d33d86 390 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 210 331 8.5E-5 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A21D_RS00745 49716e6e040907fb6d37a34076d33d86 390 Gene3D G3DSA:3.40.50.2000 196 377 8.2E-14 T 28-03-2018 A21D_RS04890 933be327f383d7a316b04befec87154c 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 250 1.8E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04890 933be327f383d7a316b04befec87154c 258 Gene3D G3DSA:1.10.3720.10 1 246 2.5E-42 T 28-03-2018 A21D_RS04890 933be327f383d7a316b04befec87154c 258 SUPERFAMILY SSF161098 2 258 1.13E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Gene3D G3DSA:3.40.50.970 591 805 5.9E-48 T 28-03-2018 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 SMART SM00861 595 791 3.5E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 2 943 22.6 T 28-03-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Gene3D G3DSA:3.40.50.970 154 529 2.4E-82 T 28-03-2018 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 940 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 SUPERFAMILY SSF52518 577 788 1.08E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 16 48 6.7E-7 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Pfam PF00676 Dehydrogenase E1 component 221 528 3.9E-65 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Gene3D G3DSA:1.10.287.1150 70 153 4.9E-10 T 28-03-2018 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 SUPERFAMILY SSF52518 151 528 1.09E-71 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12840 a204de69696fcb165a760160f632aa83 951 PIRSF PIRSF000157 1 943 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 797 940 6.2E-38 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A21D_RS12840 a204de69696fcb165a760160f632aa83 951 Pfam PF02779 Transketolase, pyrimidine binding domain 594 789 3.1E-54 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS16305 e17591eabf6b9b7dcbe02b8453cacc35 152 Gene3D G3DSA:1.10.10.10 8 97 1.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16305 e17591eabf6b9b7dcbe02b8453cacc35 152 Pfam PF01475 Ferric uptake regulator family 16 136 9.3E-40 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A21D_RS16305 e17591eabf6b9b7dcbe02b8453cacc35 152 SUPERFAMILY SSF46785 7 141 4.99E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 SUPERFAMILY SSF55804 489 613 4.19E-18 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Gene3D G3DSA:1.10.1790.10 287 391 6.3E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 499 613 6.5E-16 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Gene3D G3DSA:1.10.1790.10 180 280 0.0098 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Pfam PF08279 HTH domain 6 55 3.4E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Gene3D G3DSA:1.10.10.10 76 147 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Gene3D G3DSA:1.10.10.10 2 64 3.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Pfam PF00874 PRD domain 299 385 3.5E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 Gene3D G3DSA:3.40.930.10 477 614 1.1E-14 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS07890 201caa63e0c60154cfc78c6feb7b7d0f 615 SUPERFAMILY SSF63520 290 385 3.53E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS05885 44f9c0a66f738bbbba17bd11d54fc617 310 SUPERFAMILY SSF103481 229 307 1.57E-7 T 28-03-2018 A21D_RS05885 44f9c0a66f738bbbba17bd11d54fc617 310 SUPERFAMILY SSF103481 44 136 1.11E-9 T 28-03-2018 A21D_RS05885 44f9c0a66f738bbbba17bd11d54fc617 310 Pfam PF00892 EamA-like transporter family 168 307 2.6E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS05885 44f9c0a66f738bbbba17bd11d54fc617 310 Pfam PF00892 EamA-like transporter family 1 136 3.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 SUPERFAMILY SSF51161 3 185 1.26E-51 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 Gene3D G3DSA:2.160.10.10 1 188 4.6E-49 T 28-03-2018 A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 SMART SM01266 5 59 2.5E-20 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 Pfam PF12464 Maltose acetyltransferase 7 58 2.4E-16 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 95 110 0.016 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS08155 83bd43028b6413e2b4cfb3be42353338 188 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 130 163 6.3E-10 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 Gene3D G3DSA:1.10.600.10 2 323 8.5E-90 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 322 3.0E-145 T 28-03-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 Pfam PF00348 Polyprenyl synthetase 30 274 1.9E-66 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 SUPERFAMILY SSF48576 6 322 5.12E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain A21D_RS16600 92de7528ebc6210b1f635edc6716421c 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 Pfam PF00411 Ribosomal protein S11 19 128 3.6E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 PIRSF PIRSF002131 1 129 1.9E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 Gene3D G3DSA:3.30.420.80 5 129 1.9E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.7E-59 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 34.475 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A21D_RS06245 fecb2a80ea6d06c6da1b4b8f6e4acd87 129 SUPERFAMILY SSF53137 14 129 3.2E-49 T 28-03-2018 A21D_RS14290 6485ab3b55afa9cd6f767e08c99784b4 146 Gene3D G3DSA:3.40.50.450 1 145 1.4E-24 T 28-03-2018 A21D_RS14290 6485ab3b55afa9cd6f767e08c99784b4 146 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 146 1.2E-68 T 28-03-2018 IPR019884 YtoQ family protein A21D_RS14290 6485ab3b55afa9cd6f767e08c99784b4 146 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 145 3.0E-64 T 28-03-2018 IPR019884 YtoQ family protein A21D_RS04465 2000c2b7850a69c12112cc8b770c20a5 109 Pfam PF12116 Stage III sporulation protein D 16 94 1.1E-39 T 28-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A21D_RS04465 2000c2b7850a69c12112cc8b770c20a5 109 ProSitePatterns PS00894 DeoR-type HTH domain signature. 22 55 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS04465 2000c2b7850a69c12112cc8b770c20a5 109 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 16 94 5.8E-43 T 28-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A21D_RS04465 2000c2b7850a69c12112cc8b770c20a5 109 Gene3D G3DSA:1.10.260.40 46 90 6.8E-5 T 28-03-2018 A21D_RS04465 2000c2b7850a69c12112cc8b770c20a5 109 Gene3D G3DSA:1.10.10.10 10 45 2.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19015 d7a516cb76883b1eb86fb8923461d2e5 88 SMART SM00834 1 42 0.0016 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A21D_RS19015 d7a516cb76883b1eb86fb8923461d2e5 88 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 2.9E-9 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A21D_RS19015 d7a516cb76883b1eb86fb8923461d2e5 88 Pfam PF09723 Zinc ribbon domain 1 41 4.7E-10 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 Pfam PF07687 Peptidase dimerisation domain 173 264 2.4E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 PIRSF PIRSF005962 1 372 5.0E-91 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 SUPERFAMILY SSF53187 3 185 5.43E-57 T 28-03-2018 A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 SUPERFAMILY SSF53187 284 370 5.43E-57 T 28-03-2018 A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 11 357 7.5E-81 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 SUPERFAMILY SSF55031 173 275 1.79E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 Pfam PF01546 Peptidase family M20/M25/M40 67 368 1.1E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS12360 b825dbf7974352e2afc2d2e33ff6d75c 373 Gene3D G3DSA:3.40.630.10 2 372 8.6E-47 T 28-03-2018 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 Pfam PF13242 HAD-hyrolase-like 175 221 5.0E-13 T 28-03-2018 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 221 9.2E-44 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 Gene3D G3DSA:3.40.50.1000 68 175 4.4E-26 T 28-03-2018 IPR023214 HAD-like domain A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 176 214 3.5E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 SUPERFAMILY SSF55811 246 396 1.3E-35 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 ProSitePatterns PS00893 Nudix box signature. 299 320 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 PRINTS PR00502 NUDIX hydrolase family signature 308 323 7.9E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 PRINTS PR00502 NUDIX hydrolase family signature 294 308 7.9E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 SUPERFAMILY SSF56784 7 221 3.28E-49 T 28-03-2018 IPR023214 HAD-like domain A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 Gene3D G3DSA:3.90.79.10 248 403 9.1E-32 T 28-03-2018 A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 101 3.6E-20 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A21D_RS02205 3aece26fac705cc2f2f7c452a9486039 407 Pfam PF00293 NUDIX domain 270 389 6.8E-23 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS09480 a1b3a09d2a3e82fbec5989a79a87333b 438 PIRSF PIRSF006304 1 438 7.7E-165 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 A21D_RS09480 a1b3a09d2a3e82fbec5989a79a87333b 438 Pfam PF03611 PTS system sugar-specific permease component 4 380 1.5E-77 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 SMART SM00228 303 392 3.6E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 Pfam PF13365 Trypsin-like peptidase domain 118 265 2.0E-28 T 28-03-2018 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 Pfam PF13180 PDZ domain 303 401 7.4E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 Gene3D G3DSA:2.40.10.10 77 192 1.1E-27 T 28-03-2018 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 SUPERFAMILY SSF50494 79 300 8.3E-55 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 SUPERFAMILY SSF50156 302 402 1.71E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 236 253 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 349 361 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 130 142 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 151 171 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 258 275 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 3.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 Gene3D G3DSA:2.40.10.10 193 305 6.9E-34 T 28-03-2018 A21D_RS07405 c27679b04c23e4f1a43c11dc5fbfeacf 405 Gene3D G3DSA:2.30.42.10 306 405 5.0E-24 T 28-03-2018 A21D_RS10275 ae65607f318e9b88c940e26ca6ac95ae 91 SUPERFAMILY SSF47413 2 53 4.79E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS10275 ae65607f318e9b88c940e26ca6ac95ae 91 Pfam PF12844 Helix-turn-helix domain 4 51 1.2E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS10275 ae65607f318e9b88c940e26ca6ac95ae 91 SMART SM00530 6 61 2.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS10275 ae65607f318e9b88c940e26ca6ac95ae 91 Gene3D G3DSA:1.10.260.40 1 53 5.5E-13 T 28-03-2018 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 Gene3D G3DSA:1.10.10.60 3 36 1.2E-12 T 28-03-2018 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 Gene3D G3DSA:1.10.357.10 67 201 1.9E-4 T 28-03-2018 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 Gene3D G3DSA:1.10.260.40 37 66 3.5E-11 T 28-03-2018 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS05980 a1e48da531c20a6fce189201b52e7ea7 214 SUPERFAMILY SSF46689 6 75 1.25E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 1.7E-22 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 Pfam PF00390 Malic enzyme, N-terminal domain 20 149 1.6E-28 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 SUPERFAMILY SSF51735 161 405 1.43E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 SMART SM00919 161 385 6.6E-128 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 SMART SM01274 16 149 3.3E-80 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 SUPERFAMILY SSF53223 7 159 6.98E-55 T 28-03-2018 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 Gene3D G3DSA:3.40.50.10380 4 158 8.0E-40 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 Gene3D G3DSA:3.40.50.720 159 407 2.5E-86 T 28-03-2018 A21D_RS14530 043e259d6bda847da5f054f7a5214e67 412 PIRSF PIRSF000106 35 411 1.7E-82 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A21D_RS07880 fab5db96a201808ac13577544e931ff1 112 Pfam PF12643 MazG-like family 31 112 1.8E-22 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A21D_RS07880 fab5db96a201808ac13577544e931ff1 112 Gene3D G3DSA:1.10.4010.10 1 108 6.9E-26 T 28-03-2018 A21D_RS07880 fab5db96a201808ac13577544e931ff1 112 PIRSF PIRSF029826 1 112 3.7E-41 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A21D_RS07880 fab5db96a201808ac13577544e931ff1 112 SUPERFAMILY SSF101386 2 111 4.65E-38 T 28-03-2018 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 13 182 5.6E-68 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 19 182 2.0E-52 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 PIRSF PIRSF007510 5 185 2.1E-74 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 SUPERFAMILY SSF110710 8 187 3.4E-70 T 28-03-2018 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 Gene3D G3DSA:3.40.50.10360 8 184 7.9E-74 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 Pfam PF04260 Protein of unknown function (DUF436) 14 182 1.5E-70 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS04600 23bbfd62986fefd071a8cf79b282784e 194 Hamap MF_00800 UPF0340 protein . 1 194 76.451 T 28-03-2018 IPR006340 Protein of unknown function DUF436 A21D_RS14900 76f8287f6e2bdf26ee5cb6ac724f28dd 281 SUPERFAMILY SSF52540 4 220 1.36E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14900 76f8287f6e2bdf26ee5cb6ac724f28dd 281 SMART SM00382 27 203 4.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14900 76f8287f6e2bdf26ee5cb6ac724f28dd 281 Pfam PF00005 ABC transporter 19 154 9.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS14900 76f8287f6e2bdf26ee5cb6ac724f28dd 281 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS14900 76f8287f6e2bdf26ee5cb6ac724f28dd 281 Gene3D G3DSA:3.40.50.300 2 233 8.0E-45 T 28-03-2018 A21D_RS18830 abc222f81241a4e17ebeaa0d893a34d8 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 4.6E-22 T 28-03-2018 IPR012452 Protein of unknown function DUF1657 A21D_RS18830 abc222f81241a4e17ebeaa0d893a34d8 68 Gene3D G3DSA:1.20.1260.10 2 67 3.0E-4 T 28-03-2018 IPR012347 Ferritin-related A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Pfam PF00877 NlpC/P60 family 230 332 1.9E-32 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 SUPERFAMILY SSF54001 211 334 1.42E-43 T 28-03-2018 A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 SUPERFAMILY SSF47090 44 105 1.4E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Gene3D G3DSA:1.20.141.10 120 216 6.6E-10 T 28-03-2018 A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Gene3D G3DSA:1.20.141.10 27 119 9.8E-14 T 28-03-2018 A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Pfam PF01471 Putative peptidoglycan binding domain 130 163 3.4E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Pfam PF01471 Putative peptidoglycan binding domain 50 105 1.6E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 SUPERFAMILY SSF47090 121 172 6.28E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16855 cedb7a16ab50d94e8202328e95686626 335 Gene3D G3DSA:3.90.1720.10 217 335 7.9E-39 T 28-03-2018 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 447 501 7.5E-14 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 Gene3D G3DSA:1.10.287.510 154 477 0.0024 T 28-03-2018 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 PRINTS PR01005 Flagellar hook-associated protein signature 469 493 2.5E-5 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 2.5E-5 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 501 1.9E-113 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 SUPERFAMILY SSF64518 274 501 9.15E-22 T 28-03-2018 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 SUPERFAMILY SSF64518 167 244 9.15E-22 T 28-03-2018 A21D_RS00855 c010e95fdc48bf73b402e254307bd2d8 508 Pfam PF00460 Flagella basal body rod protein 7 37 1.4E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 Gene3D G3DSA:3.20.20.70 1 328 1.6E-158 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 323 8.9E-156 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 SMART SM01004 5 324 3.8E-243 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 SUPERFAMILY SSF51569 5 325 1.34E-144 T 28-03-2018 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 243 255 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 153 172 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 243 259 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 268 283 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 298 317 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 191 210 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 123 137 4.5E-61 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS15125 f074dcc428946d719b5e7d951f18e6d2 329 PIRSF PIRSF001415 1 327 2.8E-158 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A21D_RS13110 6e506ff570fab078484e1704d93ca5bc 299 SUPERFAMILY SSF53850 41 298 1.02E-82 T 28-03-2018 A21D_RS13110 6e506ff570fab078484e1704d93ca5bc 299 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 44 286 5.3E-61 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS13110 6e506ff570fab078484e1704d93ca5bc 299 Gene3D G3DSA:3.40.190.10 29 136 1.3E-16 T 28-03-2018 A21D_RS13110 6e506ff570fab078484e1704d93ca5bc 299 Gene3D G3DSA:3.40.190.100 137 247 4.4E-38 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 328 349 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 408 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 136 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 435 1.2E-49 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 Gene3D G3DSA:3.30.390.30 345 446 1.9E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 SUPERFAMILY SSF51905 1 320 6.83E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 Gene3D G3DSA:3.50.50.60 2 175 2.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 SUPERFAMILY SSF55424 333 442 2.92E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 439 1.0E-22 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PIRSF PIRSF000350 2 443 2.0E-76 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 Gene3D G3DSA:3.50.50.60 176 344 1.6E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 3.5E-29 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 3.5E-29 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 3.5E-29 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.5E-29 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 3.5E-29 T 28-03-2018 A21D_RS17190 8f4234624a193a931de4db56846d5ee2 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 300 8.1E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Pfam PF00970 Oxidoreductase FAD-binding domain 6 93 6.1E-5 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 PIRSF PIRSF006816 1 251 9.6E-71 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Gene3D G3DSA:2.10.240.10 210 249 4.2E-18 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Gene3D G3DSA:3.40.50.80 100 203 5.3E-11 T 28-03-2018 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 SUPERFAMILY SSF52343 90 249 2.36E-31 T 28-03-2018 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 250 35.454 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Gene3D G3DSA:2.40.30.10 1 93 3.8E-13 T 28-03-2018 A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 210 248 1.0E-17 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A21D_RS18275 704e6c72ca00e52efaa920ea43084182 251 SUPERFAMILY SSF63380 3 95 7.17E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 SUPERFAMILY SSF46894 137 208 2.99E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 Gene3D G3DSA:3.40.50.2300 1 133 4.1E-37 T 28-03-2018 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 6.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 Gene3D G3DSA:1.10.10.10 134 207 3.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 SMART SM00448 2 115 8.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 Pfam PF00072 Response regulator receiver domain 4 116 1.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 SMART SM00421 145 202 8.3E-30 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00365 2718c065aa4994da20cafb78b1e687ca 209 SUPERFAMILY SSF52172 2 134 7.26E-33 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS06455 11ac5b69a289d74b0ec255fe8f056ae8 49 Pfam PF00471 Ribosomal protein L33 3 49 1.8E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06455 11ac5b69a289d74b0ec255fe8f056ae8 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.8E-18 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06455 11ac5b69a289d74b0ec255fe8f056ae8 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 17.732 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06455 11ac5b69a289d74b0ec255fe8f056ae8 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06455 11ac5b69a289d74b0ec255fe8f056ae8 49 SUPERFAMILY SSF57829 1 49 5.95E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Gene3D G3DSA:3.40.50.720 4 89 0.0033 T 28-03-2018 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Gene3D G3DSA:3.40.1190.10 90 294 3.4E-39 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 SUPERFAMILY SSF53623 87 291 1.44E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 SUPERFAMILY SSF53244 293 429 1.81E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Pfam PF08245 Mur ligase middle domain 106 274 1.2E-27 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 432 34.045 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Pfam PF01225 Mur ligase family, catalytic domain 3 101 1.6E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 SUPERFAMILY SSF51984 2 87 4.71E-19 T 28-03-2018 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 428 6.2E-130 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Gene3D G3DSA:3.90.190.20 295 432 1.3E-22 T 28-03-2018 A21D_RS14320 82d5588d5c18baf996620da0c738d586 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 375 1.5E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS04815 7a7bdca9335be17deeda6818110b24ed 315 PIRSF PIRSF000428 1 315 3.5E-108 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS04815 7a7bdca9335be17deeda6818110b24ed 315 Gene3D G3DSA:3.40.50.10750 135 288 4.6E-63 T 28-03-2018 A21D_RS04815 7a7bdca9335be17deeda6818110b24ed 315 SUPERFAMILY SSF53659 3 315 3.17E-92 T 28-03-2018 A21D_RS04815 7a7bdca9335be17deeda6818110b24ed 315 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 12 312 1.9E-125 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS04815 7a7bdca9335be17deeda6818110b24ed 315 Pfam PF01515 Phosphate acetyl/butaryl transferase 2 312 3.5E-127 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS19495 bb645a2207af0c2859bbbb4fbc37767e 367 SUPERFAMILY SSF89392 76 227 2.55E-9 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A21D_RS19495 bb645a2207af0c2859bbbb4fbc37767e 367 Pfam PF03888 MucB/RseB N-terminal domain 102 190 3.7E-6 T 28-03-2018 IPR033434 MucB/RseB, N-terminal A21D_RS19495 bb645a2207af0c2859bbbb4fbc37767e 367 Gene3D G3DSA:2.50.20.10 23 287 6.9E-24 T 28-03-2018 A21D_RS15965 c917bf835597f74b77a1e29485cee1ae 152 PIRSF PIRSF021292 13 152 2.5E-29 T 28-03-2018 IPR016785 ComG operon protein 4 GO:0030420 A21D_RS15965 c917bf835597f74b77a1e29485cee1ae 152 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 39 6.4E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A21D_RS15965 c917bf835597f74b77a1e29485cee1ae 152 Gene3D G3DSA:3.30.700.10 19 137 6.0E-6 T 28-03-2018 A21D_RS15965 c917bf835597f74b77a1e29485cee1ae 152 SUPERFAMILY SSF54523 19 91 4.63E-8 T 28-03-2018 A21D_RS19610 70a9100593759ae15cb3b5cec8b20cce 143 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 133 1.4E-25 T 28-03-2018 IPR006480 Bacteriophage holin family A21D_RS19610 70a9100593759ae15cb3b5cec8b20cce 143 Pfam PF05105 Bacteriophage holin family 12 126 2.9E-36 T 28-03-2018 IPR006480 Bacteriophage holin family A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 Gene3D G3DSA:1.20.1260.10 14 88 4.0E-10 T 28-03-2018 IPR012347 Ferritin-related A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 Gene3D G3DSA:1.20.1260.10 89 217 2.2E-18 T 28-03-2018 IPR012347 Ferritin-related A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 Pfam PF09968 Uncharacterized protein domain (DUF2202) 180 301 9.8E-7 T 28-03-2018 IPR019243 Domain of unknown function DUF2202 A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 Pfam PF13668 Ferritin-like domain 27 147 2.1E-6 T 28-03-2018 A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 SUPERFAMILY SSF47240 23 148 1.18E-23 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 Gene3D G3DSA:1.20.1260.10 218 304 1.0E-5 T 28-03-2018 IPR012347 Ferritin-related A21D_RS07905 15dc18aa81f7ab44158980af88539cd2 304 SUPERFAMILY SSF47240 173 302 3.57E-15 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS14735 9ea3d376dc3916265e88308d3dd3eade 74 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 2.1E-34 T 28-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A21D_RS14735 9ea3d376dc3916265e88308d3dd3eade 74 Pfam PF14098 Small, acid-soluble spore protein I 3 66 1.7E-27 T 28-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A21D_RS14735 9ea3d376dc3916265e88308d3dd3eade 74 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 20.828 T 28-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A21D_RS19090 32455b02c8bb8ecdba0dbb9e5f5d4a1e 1177 Gene3D G3DSA:1.20.58.60 210 840 3.4E-6 T 28-03-2018 A21D_RS19090 32455b02c8bb8ecdba0dbb9e5f5d4a1e 1177 Gene3D G3DSA:1.20.58.60 841 932 0.11 T 28-03-2018 A21D_RS19090 32455b02c8bb8ecdba0dbb9e5f5d4a1e 1177 Gene3D G3DSA:3.40.1710.10 35 206 3.6E-20 T 28-03-2018 A21D_RS19090 32455b02c8bb8ecdba0dbb9e5f5d4a1e 1177 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 10 203 3.2E-71 T 28-03-2018 IPR023838 Type VII secretion system EsaA GO:0016021 A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 SUPERFAMILY SSF82689 202 300 1.31E-11 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 SUPERFAMILY SSF50182 136 199 5.23E-16 T 28-03-2018 IPR010920 LSM domain A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 Gene3D G3DSA:2.30.30.60 151 200 3.3E-16 T 28-03-2018 A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 SUPERFAMILY SSF82861 42 134 6.02E-15 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 Gene3D G3DSA:3.30.70.100 202 295 1.0E-11 T 28-03-2018 A21D_RS07305 4f94756095af7b518faa87c900a15ab7 342 Pfam PF00924 Mechanosensitive ion channel 92 290 1.2E-43 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 SUPERFAMILY SSF51735 140 308 1.36E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 SMART SM00829 13 343 0.0096 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 2.7E-30 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 Gene3D G3DSA:3.40.50.10730 168 325 3.1E-31 T 28-03-2018 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 SUPERFAMILY SSF50129 1 155 1.22E-55 T 28-03-2018 IPR011032 GroES-like A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 Pfam PF00107 Zinc-binding dehydrogenase 177 293 6.8E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 Gene3D G3DSA:3.90.180.10 1 167 1.4E-48 T 28-03-2018 A21D_RS08590 1e9023d15c5451ebc546b8cab6e29374 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 Gene3D G3DSA:3.20.20.70 1 286 1.9E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 283 1.0E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 SUPERFAMILY SSF51569 1 283 4.98E-93 T 28-03-2018 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 PIRSF PIRSF001359 1 284 2.3E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS08565 e392a421f8f34347b9054107cf2905d3 290 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 283 4.0E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Pfam PF02817 e3 binding domain 127 162 6.7E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 SUPERFAMILY SSF47005 124 166 1.96E-8 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 189 417 1.5E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Gene3D G3DSA:2.40.50.100 46 121 1.8E-6 T 28-03-2018 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Pfam PF00364 Biotin-requiring enzyme 2 75 4.3E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Gene3D G3DSA:3.90.1170.30 1 45 4.7E-16 T 28-03-2018 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 419 1.3E-165 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 SUPERFAMILY SSF51230 2 92 1.01E-26 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Gene3D G3DSA:3.30.559.10 177 418 8.2E-88 T 28-03-2018 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 SUPERFAMILY SSF52777 189 418 2.31E-86 T 28-03-2018 A21D_RS12845 c114c973f0b7058cda9817adc0dc5476 420 Gene3D G3DSA:4.10.320.10 122 176 4.8E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS01020 f208459dd6a62a45a5549994c80f52ee 293 Gene3D G3DSA:1.10.287.950 116 291 5.0E-37 T 28-03-2018 A21D_RS01020 f208459dd6a62a45a5549994c80f52ee 293 SMART SM00283 82 292 4.4E-5 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS01020 f208459dd6a62a45a5549994c80f52ee 293 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 159 285 3.5E-27 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS01020 f208459dd6a62a45a5549994c80f52ee 293 SUPERFAMILY SSF103190 41 125 7.06E-7 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS01020 f208459dd6a62a45a5549994c80f52ee 293 SUPERFAMILY SSF58104 120 290 3.92E-41 T 28-03-2018 A21D_RS12145 60ea63d679a6e861544778903fe2e70f 164 Gene3D G3DSA:2.40.260.10 2 164 1.6E-36 T 28-03-2018 IPR023365 Sortase domain A21D_RS12145 60ea63d679a6e861544778903fe2e70f 164 SUPERFAMILY SSF63817 22 163 1.7E-33 T 28-03-2018 IPR023365 Sortase domain A21D_RS12145 60ea63d679a6e861544778903fe2e70f 164 TIGRFAM TIGR01076 sortase_fam: sortase 39 159 5.8E-31 T 28-03-2018 IPR005754 Sortase family A21D_RS12145 60ea63d679a6e861544778903fe2e70f 164 Pfam PF04203 Sortase family 41 161 1.0E-27 T 28-03-2018 IPR005754 Sortase family A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Gene3D G3DSA:2.120.10.90 501 825 2.5E-130 T 28-03-2018 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 807 0.0 T 28-03-2018 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 4 809 24.909 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Gene3D G3DSA:3.30.1360.40 238 334 1.3E-38 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Gene3D G3DSA:3.90.199.10 35 216 9.4E-85 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 SUPERFAMILY SSF101904 501 822 2.75E-115 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 473 5.4E-161 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 5.7E-18 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 712 758 1.0E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 807 1.1E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 606 2.5E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 552 1.9E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 656 6.8E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 SUPERFAMILY SSF56719 31 489 2.22E-182 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 SMART SM00434 12 466 2.5E-294 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS07200 f6937d9ef2eff09b1347b770288bca4a 829 Gene3D G3DSA:1.10.268.10 346 488 9.1E-54 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 Gene3D G3DSA:3.40.50.1390 1 120 5.4E-38 T 28-03-2018 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 Pfam PF00239 Resolvase, N terminal domain 3 146 4.1E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 Pfam PF13408 Recombinase zinc beta ribbon domain 286 345 9.6E-13 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 Gene3D G3DSA:1.20.5.40 121 148 8.3E-11 T 28-03-2018 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 SUPERFAMILY SSF53041 1 147 1.31E-35 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 SMART SM00857 3 151 1.8E-52 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A21D_RS17460 fddbb5a56c17581e7a23b1f36d5dd6ec 476 Pfam PF07508 Recombinase 173 274 7.9E-23 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A21D_RS05135 b2b7f30a8121d1dd74142870d635a653 74 SUPERFAMILY SSF47413 1 66 1.13E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS05135 b2b7f30a8121d1dd74142870d635a653 74 SMART SM00530 6 62 6.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS05135 b2b7f30a8121d1dd74142870d635a653 74 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 1.6E-22 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS05135 b2b7f30a8121d1dd74142870d635a653 74 Gene3D G3DSA:1.10.260.40 3 74 2.8E-9 T 28-03-2018 A21D_RS12075 148ffbb1a24d553512169fb9d02232f9 465 Pfam PF07670 Nucleoside recognition 138 230 6.1E-9 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS12075 148ffbb1a24d553512169fb9d02232f9 465 Pfam PF07670 Nucleoside recognition 308 432 1.4E-17 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS12075 148ffbb1a24d553512169fb9d02232f9 465 Pfam PF07664 Ferrous iron transport protein B C terminus 250 299 4.1E-14 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A21D_RS15055 87fce80a270f1e43c1d85d3c921262e6 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 145 1.2E-32 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A21D_RS15055 87fce80a270f1e43c1d85d3c921262e6 169 SUPERFAMILY SSF56300 1 164 9.77E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS15055 87fce80a270f1e43c1d85d3c921262e6 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 142 1.9E-31 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A21D_RS15055 87fce80a270f1e43c1d85d3c921262e6 169 Gene3D G3DSA:3.60.21.10 2 166 1.1E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 Pfam PF09182 Bacterial purine repressor, N-terminal 2 71 1.5E-22 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 Pfam PF00156 Phosphoribosyl transferase domain 107 263 2.5E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 Gene3D G3DSA:3.40.50.2020 72 270 7.2E-34 T 28-03-2018 A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 Gene3D G3DSA:1.10.10.10 1 71 2.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 SUPERFAMILY SSF53271 94 253 1.7E-37 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 7 71 1.0E-18 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 1 269 3.5E-109 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 A21D_RS06770 d634449e121bb8a6525a286076b657a4 270 SUPERFAMILY SSF46785 1 71 4.35E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 9 333 3.6E-134 T 28-03-2018 IPR030827 Inositol 2-dehydrogenase A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 SUPERFAMILY SSF55347 134 294 2.29E-32 T 28-03-2018 A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 Gene3D G3DSA:3.40.50.720 1 137 2.3E-36 T 28-03-2018 A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 233 1.9E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 SUPERFAMILY SSF51735 9 152 7.29E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 125 4.5E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A21D_RS01995 b7c7558efd571aa9cd379d0d4ba766a9 339 Gene3D G3DSA:3.30.360.10 138 339 1.3E-40 T 28-03-2018 A21D_RS08670 b305dd313bc70fb0825878f4ac9b48e9 256 Pfam PF07556 Protein of unknown function (DUF1538) 24 232 6.2E-73 T 28-03-2018 IPR011435 Protein of unknown function DUF1538 A21D_RS08670 b305dd313bc70fb0825878f4ac9b48e9 256 Gene3D G3DSA:2.20.25.10 229 255 0.0016 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PIRSF PIRSF000723 2 313 5.7E-125 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 Pfam PF00696 Amino acid kinase family 4 295 6.6E-34 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 267 282 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 212 227 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 1.4E-61 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 SUPERFAMILY SSF53633 4 311 5.89E-83 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 Gene3D G3DSA:3.40.1160.10 2 313 2.9E-60 T 28-03-2018 A21D_RS07960 3071caa67d287e0f2443e27d970cd780 313 TIGRFAM TIGR00746 arcC: carbamate kinase 4 312 1.3E-129 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 Hamap MF_00258 Glutamate racemase [murI]. 3 256 39.518 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 Gene3D G3DSA:3.40.50.1860 120 271 2.0E-44 T 28-03-2018 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 252 4.1E-88 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 215 7.2E-41 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 Gene3D G3DSA:3.40.50.1860 1 119 1.1E-29 T 28-03-2018 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 SUPERFAMILY SSF53681 4 106 1.41E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS15035 477aac4525cffe2eb53b05800c9c1f32 275 SUPERFAMILY SSF53681 108 256 1.06E-37 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS02250 4acee64abb34baeea03e599225dca5ba 70 SUPERFAMILY SSF56601 3 66 7.74E-8 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS02250 4acee64abb34baeea03e599225dca5ba 70 Gene3D G3DSA:3.40.710.10 2 67 1.5E-8 T 28-03-2018 A21D_RS02250 4acee64abb34baeea03e599225dca5ba 70 Pfam PF00144 Beta-lactamase 8 66 3.3E-5 T 28-03-2018 IPR001466 Beta-lactamase-related A21D_RS16425 06788267f3fb9fe783fd01449cee64ef 190 SUPERFAMILY SSF52833 47 187 4.13E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS16425 06788267f3fb9fe783fd01449cee64ef 190 Gene3D G3DSA:3.40.30.10 37 187 4.9E-38 T 28-03-2018 A21D_RS16425 06788267f3fb9fe783fd01449cee64ef 190 Pfam PF00578 AhpC/TSA family 49 169 8.0E-36 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 SUPERFAMILY SSF51306 32 175 2.44E-47 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 Gene3D G3DSA:2.10.109.10 29 176 4.7E-45 T 28-03-2018 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 ProSitePatterns PS00760 Signal peptidases I lysine active site. 84 96 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 82 94 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 129 148 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 33 49 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 16 171 6.2E-52 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 ProSitePatterns PS00761 Signal peptidases I signature 3. 134 147 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 ProSitePatterns PS00501 Signal peptidases I serine active site. 42 49 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A21D_RS18785 f179ea4d9b680019684204c783c49de5 177 Pfam PF00717 Peptidase S24-like 40 106 2.3E-18 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS09655 03aa3c4f89ba4cfd56a44cfd41ebd6b2 222 Pfam PF04012 PspA/IM30 family 5 219 1.1E-46 T 28-03-2018 IPR007157 PspA/IM30 A21D_RS09655 03aa3c4f89ba4cfd56a44cfd41ebd6b2 222 Gene3D G3DSA:3.90.20.10 116 221 8.0E-4 T 28-03-2018 A21D_RS07580 c20f1daaa9a7ebbcf21adb6c83d8c430 167 SUPERFAMILY SSF54909 56 106 5.63E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS07580 c20f1daaa9a7ebbcf21adb6c83d8c430 167 Gene3D G3DSA:3.30.70.100 37 114 0.0012 T 28-03-2018 A21D_RS07580 c20f1daaa9a7ebbcf21adb6c83d8c430 167 Pfam PF13826 Domain of unknown function (DUF4188) 18 135 1.4E-45 T 28-03-2018 IPR025444 Monooxygenase af470-like A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 Pfam PF13365 Trypsin-like peptidase domain 111 247 3.4E-12 T 28-03-2018 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 Gene3D G3DSA:2.40.10.10 178 273 8.2E-11 T 28-03-2018 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 Gene3D G3DSA:2.20.28.20 2 27 2.1E-4 T 28-03-2018 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 PRINTS PR00834 HtrA/DegQ protease family signature 181 205 2.9E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 PRINTS PR00834 HtrA/DegQ protease family signature 140 160 2.9E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 PRINTS PR00834 HtrA/DegQ protease family signature 120 132 2.9E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 PRINTS PR00834 HtrA/DegQ protease family signature 217 234 2.9E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 Gene3D G3DSA:2.40.10.10 60 177 9.9E-14 T 28-03-2018 A21D_RS12090 3f95f5afcd2c9b8ffd636fb45d6b0bc9 438 SUPERFAMILY SSF50494 93 276 1.04E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS15330 14ccd49c57870d6ad52f2faeadad3f25 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 169 6.0E-69 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A21D_RS15330 14ccd49c57870d6ad52f2faeadad3f25 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.855 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A21D_RS15330 14ccd49c57870d6ad52f2faeadad3f25 170 SUPERFAMILY SSF53271 2 163 4.4E-49 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS15330 14ccd49c57870d6ad52f2faeadad3f25 170 Pfam PF00156 Phosphoribosyl transferase domain 32 148 6.3E-16 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS15330 14ccd49c57870d6ad52f2faeadad3f25 170 Gene3D G3DSA:3.40.50.2020 1 169 2.5E-37 T 28-03-2018 A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 SUPERFAMILY SSF46785 1 111 1.14E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 Pfam PF03466 LysR substrate binding domain 87 281 9.1E-27 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 Gene3D G3DSA:1.10.10.10 1 86 2.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 Gene3D G3DSA:3.40.190.10 173 245 2.6E-10 T 28-03-2018 A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.2E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 Gene3D G3DSA:3.40.190.10 91 172 4.0E-8 T 28-03-2018 A21D_RS18250 30c8f6b56ace15a478d131d905c3d653 289 SUPERFAMILY SSF53850 88 285 3.62E-26 T 28-03-2018 A21D_RS01915 ff0117118e1fcb0d32e2da37e8b3b3f5 91 SUPERFAMILY SSF52794 1 89 1.2E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS01915 ff0117118e1fcb0d32e2da37e8b3b3f5 91 Gene3D G3DSA:3.40.50.2300 1 91 1.7E-21 T 28-03-2018 A21D_RS01915 ff0117118e1fcb0d32e2da37e8b3b3f5 91 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 80 5.3E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 SMART SM00788 3 422 1.3E-288 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 8.8E-182 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 208.171 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 4.1E-192 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 Gene3D G3DSA:3.90.170.10 265 428 7.9E-67 T 28-03-2018 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 SUPERFAMILY SSF52540 1 426 1.91E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 Gene3D G3DSA:3.40.440.10 151 264 5.6E-28 T 28-03-2018 A21D_RS07370 156a938553e4192bdfae1fb82c181db6 428 Gene3D G3DSA:3.40.440.10 1 150 3.7E-53 T 28-03-2018 A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 SUPERFAMILY SSF51735 9 263 1.04E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 Pfam PF00106 short chain dehydrogenase 11 202 1.6E-55 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS02375 a94363bd8b17ebaa5947ddbe05e4a670 266 Gene3D G3DSA:3.40.50.720 6 265 1.9E-64 T 28-03-2018 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 SUPERFAMILY SSF158472 89 132 7.06E-5 T 28-03-2018 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 7.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 7.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 7.3E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 Gene3D G3DSA:3.30.565.10 203 363 4.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 SUPERFAMILY SSF47384 128 208 7.65E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 SUPERFAMILY SSF55874 197 362 3.41E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 SMART SM00387 253 363 1.7E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 Gene3D G3DSA:1.10.287.130 128 202 6.5E-14 T 28-03-2018 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 SMART SM00388 141 208 3.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03490 e780039ab129bcb3e792f17942dda2dd 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 362 3.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 Pfam PF06199 Phage tail tube protein 8 145 5.2E-26 T 28-03-2018 IPR011855 Phage major tail protein TP901-1 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01997 Phage major tail protein 2 family signature 108 129 1.7E-22 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01997 Phage major tail protein 2 family signature 80 98 1.7E-22 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01997 Phage major tail protein 2 family signature 132 151 1.7E-22 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01997 Phage major tail protein 2 family signature 50 68 1.7E-22 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01997 Phage major tail protein 2 family signature 28 50 1.7E-22 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 7 140 8.3E-34 T 28-03-2018 IPR011855 Phage major tail protein TP901-1 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01998 Staphylococcal phage major tail protein signature 70 98 5.5E-5 T 28-03-2018 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01998 Staphylococcal phage major tail protein signature 154 172 5.5E-5 T 28-03-2018 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01998 Staphylococcal phage major tail protein signature 14 37 5.5E-5 T 28-03-2018 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01998 Staphylococcal phage major tail protein signature 108 126 5.5E-5 T 28-03-2018 A21D_RS05485 cbefeba5c02d1a28022b2ea0ae02a0f2 173 PRINTS PR01998 Staphylococcal phage major tail protein signature 41 64 5.5E-5 T 28-03-2018 A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 Gene3D G3DSA:3.30.830.10 220 404 7.5E-40 T 28-03-2018 A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 SUPERFAMILY SSF63411 3 204 3.49E-57 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 Pfam PF05193 Peptidase M16 inactive domain 166 338 5.7E-36 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 Gene3D G3DSA:3.30.830.10 1 219 1.2E-58 T 28-03-2018 A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 6.5E-45 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 SUPERFAMILY SSF63411 226 401 1.83E-43 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17690 5b9c1568b43dc1c6b7b10d4c190b2a8a 406 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A21D_RS08950 e21475b3003b4bb28bd67e3f4b1620dc 254 SUPERFAMILY SSF52540 5 229 4.03E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08950 e21475b3003b4bb28bd67e3f4b1620dc 254 Pfam PF00005 ABC transporter 28 174 3.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08950 e21475b3003b4bb28bd67e3f4b1620dc 254 Gene3D G3DSA:3.40.50.300 1 242 4.3E-62 T 28-03-2018 A21D_RS08950 e21475b3003b4bb28bd67e3f4b1620dc 254 SMART SM00382 35 222 1.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00045 526e9edf52d26ec81f09b52134693ee7 556 Pfam PF03354 Phage Terminase 65 539 2.1E-35 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SUPERFAMILY SSF52540 288 509 2.85E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SUPERFAMILY SSF160443 703 779 2.09E-8 T 28-03-2018 IPR002625 Smr domain A21D_RS14775 72452994a48694723a8ddc741054e75c 780 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 780 6.0E-253 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SUPERFAMILY SSF48334 20 282 1.96E-28 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Gene3D G3DSA:1.20.120.20 503 772 0.015 T 28-03-2018 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Pfam PF01713 Smr domain 705 780 2.3E-18 T 28-03-2018 IPR002625 Smr domain A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Gene3D G3DSA:1.10.1420.10 15 284 2.2E-7 T 28-03-2018 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 779 21.46 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 PIRSF PIRSF005814 1 780 4.0E-265 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Pfam PF00488 MutS domain V 326 505 5.3E-33 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SMART SM00533 9 310 3.9E-24 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SMART SM00534 323 508 4.2E-71 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A21D_RS14775 72452994a48694723a8ddc741054e75c 780 SMART SM00463 702 780 4.4E-20 T 28-03-2018 IPR002625 Smr domain A21D_RS14775 72452994a48694723a8ddc741054e75c 780 Gene3D G3DSA:3.40.50.300 287 502 1.1E-30 T 28-03-2018 A21D_RS10585 e76a5b89ca95e3bf5b1f5d7c41c1c883 626 Gene3D G3DSA:1.20.1480.30 354 475 8.3E-8 T 28-03-2018 A21D_RS10585 e76a5b89ca95e3bf5b1f5d7c41c1c883 626 Gene3D G3DSA:1.10.287.950 479 568 8.4E-8 T 28-03-2018 A21D_RS10585 e76a5b89ca95e3bf5b1f5d7c41c1c883 626 Gene3D G3DSA:1.10.287.950 113 353 1.6E-9 T 28-03-2018 A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 SUPERFAMILY SSF52467 158 340 3.27E-34 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Gene3D G3DSA:3.40.50.970 352 547 3.1E-32 T 28-03-2018 A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 SUPERFAMILY SSF52518 1 174 2.75E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 171 2.9E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 SUPERFAMILY SSF52518 365 544 5.71E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Gene3D G3DSA:3.40.50.1220 192 351 3.1E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 534 2.3E-29 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Gene3D G3DSA:3.40.50.970 1 191 1.3E-45 T 28-03-2018 A21D_RS12245 4593d8d5004e97078460fa3fed7eff78 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 328 1.2E-32 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A21D_RS14720 9f43e3ee434db295c72168e7e81d9506 376 Gene3D G3DSA:3.40.1710.10 40 200 2.7E-14 T 28-03-2018 A21D_RS14720 9f43e3ee434db295c72168e7e81d9506 376 Pfam PF12698 ABC-2 family transporter protein 18 350 3.4E-16 T 28-03-2018 A21D_RS17235 b576f431a89797c790d6a70a251cafae 265 Gene3D G3DSA:3.40.630.40 1 185 2.2E-54 T 28-03-2018 A21D_RS17235 b576f431a89797c790d6a70a251cafae 265 Gene3D G3DSA:3.30.70.1070 216 265 0.17 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A21D_RS17235 b576f431a89797c790d6a70a251cafae 265 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 176 1.3E-50 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS17235 b576f431a89797c790d6a70a251cafae 265 SMART SM00646 64 176 1.8E-41 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS17235 b576f431a89797c790d6a70a251cafae 265 SUPERFAMILY SSF53187 1 179 1.0E-51 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Pfam PF12698 ABC-2 family transporter protein 25 183 6.4E-11 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Pfam PF01061 ABC-2 type transporter 664 778 5.0E-8 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Gene3D G3DSA:1.10.287.950 231 328 5.0E-6 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Gene3D G3DSA:3.40.1710.10 46 211 5.0E-27 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 303 322 3.1E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Gene3D G3DSA:1.20.120.570 506 611 4.3E-9 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Gene3D G3DSA:1.20.120.570 395 505 2.7E-11 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 Gene3D G3DSA:1.10.287.950 329 394 0.0015 T 28-03-2018 A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 610 808 7.0E-40 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal A21D_RS00905 1d1f891a9424a9244d167e0bdb4ac4d6 832 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 171 1.8E-53 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal A21D_RS13795 bd09fa9d1a35be2c9febe9f19a7cb921 304 Gene3D G3DSA:3.20.20.70 2 166 6.4E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS13795 bd09fa9d1a35be2c9febe9f19a7cb921 304 Pfam PF01136 Peptidase family U32 75 300 4.2E-45 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 Pfam PF01380 SIS domain 128 257 5.2E-23 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 Gene3D G3DSA:3.40.50.10490 81 276 5.3E-36 T 28-03-2018 A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 78 3.5E-20 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 SUPERFAMILY SSF53697 96 280 4.01E-40 T 28-03-2018 A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 Gene3D G3DSA:1.10.10.10 3 80 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02260 65db20da3ce958c2112c35982621dc0e 285 SUPERFAMILY SSF46689 6 78 4.12E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS17475 4213b88c4dbf1c98b55c175cdfbdad45 75 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 6 69 3.0E-11 T 28-03-2018 IPR020256 Spore coat protein CotJA A21D_RS17475 4213b88c4dbf1c98b55c175cdfbdad45 75 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 64 1.7E-11 T 28-03-2018 IPR020256 Spore coat protein CotJA A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 2.0E-24 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 70.865 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 Gene3D G3DSA:1.10.10.10 3 66 7.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 148 3.8E-54 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.9E-29 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 Gene3D G3DSA:3.30.1360.40 74 146 6.4E-30 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.4E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.4E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.4E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.4E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 SUPERFAMILY SSF55252 80 149 3.66E-23 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 SUPERFAMILY SSF46785 5 78 2.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16140 e8ba4b33a5eb8efcd057b9a5e9055271 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 2.3E-27 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A21D_RS01070 19948bce23bb2a8478f2d086da540ca4 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 83 1.5E-13 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS01070 19948bce23bb2a8478f2d086da540ca4 101 Gene3D G3DSA:3.40.50.2300 1 101 1.8E-26 T 28-03-2018 A21D_RS01070 19948bce23bb2a8478f2d086da540ca4 101 SUPERFAMILY SSF52794 1 100 2.88E-24 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS19000 cf66751d2697b02c5e244d101ec33d3a 440 Pfam PF13520 Amino acid permease 7 418 1.6E-25 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS19000 cf66751d2697b02c5e244d101ec33d3a 440 PIRSF PIRSF006060 1 440 2.4E-39 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS15275 ab87c2473649329dc662ba1c05826bd5 65 Pfam PF11146 Protein of unknown function (DUF2905) 4 61 1.4E-19 T 28-03-2018 IPR021320 Protein of unknown function DUF2905 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 Pfam PF01070 FMN-dependent dehydrogenase 177 336 9.5E-15 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 7 340 2.6E-127 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 5 343 38.952 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 PIRSF PIRSF003314 2 349 1.8E-124 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 SUPERFAMILY SSF51395 28 339 1.06E-67 T 28-03-2018 A21D_RS03100 a7461a2f7922c3511c428f6425de8f82 350 Gene3D G3DSA:3.20.20.70 5 350 6.2E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS16105 3017525002475f99b0fc61bb4787b196 126 Pfam PF01029 NusB family 4 125 5.9E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS16105 3017525002475f99b0fc61bb4787b196 126 SUPERFAMILY SSF48013 3 124 5.89E-36 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS16105 3017525002475f99b0fc61bb4787b196 126 Gene3D G3DSA:1.10.940.10 1 126 5.4E-41 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A21D_RS16105 3017525002475f99b0fc61bb4787b196 126 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 125 3.2E-39 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 A21D_RS16105 3017525002475f99b0fc61bb4787b196 126 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 126 20.744 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 SUPERFAMILY SSF53649 2 101 3.27E-75 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 SUPERFAMILY SSF53649 218 389 3.27E-75 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 Hamap MF_00740 Phosphopentomutase [deoB]. 4 388 53.842 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 386 4.5E-192 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 PIRSF PIRSF001491 3 391 2.7E-164 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 Gene3D G3DSA:3.30.70.1250 100 217 1.0E-57 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 Gene3D G3DSA:3.40.720.10 275 390 5.9E-12 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 Pfam PF01676 Metalloenzyme superfamily 5 379 2.2E-44 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A21D_RS16320 d18f0e4708d26c29f24f6f2ae7c6c313 391 SUPERFAMILY SSF143856 101 217 4.97E-51 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A21D_RS05200 d8dbe8f562bf70344eebf0dccc4e2312 276 SUPERFAMILY SSF55729 173 261 1.9E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS05200 d8dbe8f562bf70344eebf0dccc4e2312 276 Pfam PF12746 GNAT acetyltransferase 18 271 8.2E-55 T 28-03-2018 IPR027365 GNAT acetyltransferase YdfB-like A21D_RS05200 d8dbe8f562bf70344eebf0dccc4e2312 276 Gene3D G3DSA:3.40.630.30 2 261 1.6E-10 T 28-03-2018 A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 Pfam PF02219 Methylenetetrahydrofolate reductase 314 576 1.2E-26 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 Gene3D G3DSA:3.20.20.330 1 314 5.6E-83 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 Pfam PF02574 Homocysteine S-methyltransferase 12 279 2.9E-57 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 SUPERFAMILY SSF51730 313 600 1.47E-66 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 Gene3D G3DSA:3.20.20.220 315 615 8.8E-63 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS05515 508d7a9b402feb5ea6813f0cabcb612c 615 SUPERFAMILY SSF82282 2 360 2.35E-96 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A21D_RS00470 88274345d2e88f50e788721581670ed1 304 Pfam PF12146 Serine aminopeptidase, S33 27 285 1.0E-54 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A21D_RS00470 88274345d2e88f50e788721581670ed1 304 Gene3D G3DSA:3.40.50.1820 1 304 2.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS00470 88274345d2e88f50e788721581670ed1 304 SUPERFAMILY SSF53474 3 298 1.14E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS13830 2587bb23eeae1782958c637736409b59 144 PRINTS PR01438 Universal stress protein signature 2 20 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS13830 2587bb23eeae1782958c637736409b59 144 PRINTS PR01438 Universal stress protein signature 104 116 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS13830 2587bb23eeae1782958c637736409b59 144 PRINTS PR01438 Universal stress protein signature 122 144 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS13830 2587bb23eeae1782958c637736409b59 144 Pfam PF00582 Universal stress protein family 2 144 1.4E-29 T 28-03-2018 IPR006016 UspA GO:0006950 A21D_RS13830 2587bb23eeae1782958c637736409b59 144 SUPERFAMILY SSF52402 4 144 6.28E-33 T 28-03-2018 A21D_RS13830 2587bb23eeae1782958c637736409b59 144 Gene3D G3DSA:3.40.50.620 2 144 8.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 Pfam PF01546 Peptidase family M20/M25/M40 141 402 3.1E-12 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 Gene3D G3DSA:3.40.630.10 1 410 1.3E-51 T 28-03-2018 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 58.766 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 PIRSF PIRSF037215 1 410 1.0E-192 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 408 9.1E-197 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 Pfam PF07687 Peptidase dimerisation domain 209 308 4.9E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 SUPERFAMILY SSF53187 324 408 3.41E-82 T 28-03-2018 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 SUPERFAMILY SSF53187 3 212 3.41E-82 T 28-03-2018 A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 SUPERFAMILY SSF55031 211 322 6.91E-39 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS03165 1d78e96a96519bc42ef3e139324328cb 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A21D_RS17085 43d1ffb9ca7ef5a6991740738fb690d0 99 SUPERFAMILY SSF89360 2 78 8.83E-11 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS17085 43d1ffb9ca7ef5a6991740738fb690d0 99 Gene3D G3DSA:2.60.300.12 1 96 1.2E-10 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS17085 43d1ffb9ca7ef5a6991740738fb690d0 99 PIRSF PIRSF034852 1 97 2.3E-34 T 28-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 A21D_RS08475 73a099fd74093bd74ced3fac9fbbeafe 304 Pfam PF00005 ABC transporter 22 162 3.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08475 73a099fd74093bd74ced3fac9fbbeafe 304 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08475 73a099fd74093bd74ced3fac9fbbeafe 304 SMART SM00382 30 211 3.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08475 73a099fd74093bd74ced3fac9fbbeafe 304 Gene3D G3DSA:3.40.50.300 2 255 7.8E-59 T 28-03-2018 A21D_RS08475 73a099fd74093bd74ced3fac9fbbeafe 304 SUPERFAMILY SSF52540 4 223 3.46E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12945 e3d87ee4e9a76ea44c8f900d223b339e 458 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 449 2.4E-114 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A21D_RS12945 e3d87ee4e9a76ea44c8f900d223b339e 458 Pfam PF03553 Na+/H+ antiporter family 162 446 4.9E-50 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS03790 0eca472e0ea48bbb55bfad1b8193debb 270 Pfam PF13030 Protein of unknown function (DUF3891) 19 243 3.5E-55 T 28-03-2018 IPR024992 Protein of unknown function DUF3891 A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 SUPERFAMILY SSF55021 139 207 1.57E-8 T 28-03-2018 A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 Pfam PF00571 CBS domain 76 125 6.0E-12 T 28-03-2018 IPR000644 CBS domain A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 Pfam PF00571 CBS domain 3 56 1.4E-14 T 28-03-2018 IPR000644 CBS domain A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 Pfam PF01842 ACT domain 141 200 6.1E-8 T 28-03-2018 IPR002912 ACT domain A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 Gene3D G3DSA:3.10.580.10 1 139 1.6E-30 T 28-03-2018 A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 SUPERFAMILY SSF54631 1 129 2.4E-31 T 28-03-2018 A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 SMART SM00116 81 129 2.0E-10 T 28-03-2018 IPR000644 CBS domain A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 SMART SM00116 10 58 6.4E-11 T 28-03-2018 IPR000644 CBS domain A21D_RS14365 f0b49bcae6d7dfba39ecd2dc35774091 217 Gene3D G3DSA:3.30.70.260 140 206 3.3E-7 T 28-03-2018 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 Gene3D G3DSA:3.90.1300.10 1 484 1.8E-174 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 476 4.1E-203 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 SUPERFAMILY SSF75304 1 482 5.1E-166 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 476 94.819 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS11030 4008dd7aed79381e26fadcfc6ed402d5 488 Pfam PF01425 Amidase 24 464 2.2E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 Pfam PF00005 ABC transporter 24 174 5.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 SMART SM00382 32 223 1.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 SUPERFAMILY SSF52540 3 234 2.49E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 3.6E-118 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 Gene3D G3DSA:3.40.50.300 1 274 2.3E-64 T 28-03-2018 A21D_RS06225 a122f0f591db192033b260fc5d61d284 290 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS14020 e85f03a4ef67e0aa788004f5d66558e2 139 SUPERFAMILY SSF160755 1 132 1.57E-33 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS14020 e85f03a4ef67e0aa788004f5d66558e2 139 Pfam PF08868 YugN-like family 4 131 3.8E-46 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS14020 e85f03a4ef67e0aa788004f5d66558e2 139 Gene3D G3DSA:3.30.310.100 1 116 2.0E-37 T 28-03-2018 IPR014967 Uncharacterised protein family, YugN-like A21D_RS10825 6bb4cb5e5e0c54a9fa2f5917cc8e0d91 334 Gene3D G3DSA:1.20.1260.10 2 147 8.5E-14 T 28-03-2018 IPR012347 Ferritin-related A21D_RS10825 6bb4cb5e5e0c54a9fa2f5917cc8e0d91 334 Gene3D G3DSA:1.20.1260.10 172 319 1.2E-7 T 28-03-2018 IPR012347 Ferritin-related A21D_RS10825 6bb4cb5e5e0c54a9fa2f5917cc8e0d91 334 Pfam PF11553 Protein of unknown function (DUF3231) 170 331 1.3E-41 T 28-03-2018 IPR021617 Protein of unknown function DUF3231 A21D_RS10825 6bb4cb5e5e0c54a9fa2f5917cc8e0d91 334 Pfam PF11553 Protein of unknown function (DUF3231) 10 159 3.3E-37 T 28-03-2018 IPR021617 Protein of unknown function DUF3231 A21D_RS06535 cb3b6bab77201432a7dd82a4ba1a506d 323 SUPERFAMILY SSF53098 160 309 2.09E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS06535 cb3b6bab77201432a7dd82a4ba1a506d 323 Pfam PF00665 Integrase core domain 161 265 1.3E-8 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS06535 cb3b6bab77201432a7dd82a4ba1a506d 323 Gene3D G3DSA:3.30.420.10 148 318 3.7E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS06535 cb3b6bab77201432a7dd82a4ba1a506d 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS19075 327e7d2827d095bd130b42f646e36c19 429 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 26 382 1.4E-119 T 28-03-2018 IPR018778 Type VII secretion system EssB A21D_RS19075 327e7d2827d095bd130b42f646e36c19 429 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 7 382 3.6E-133 T 28-03-2018 IPR018778 Type VII secretion system EssB A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 7 180 40.574 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 8 179 4.1E-83 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 PIRSF PIRSF039093 1 181 3.0E-85 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 SUPERFAMILY SSF56235 5 180 1.87E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 Gene3D G3DSA:3.60.20.10 8 181 2.1E-27 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS17980 ea6956f267bfafa36d734f1f796f049e 181 Pfam PF00227 Proteasome subunit 6 179 4.8E-23 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A21D_RS00330 b233e14023eb469cfc674255e4463a06 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.3E-22 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A21D_RS00330 b233e14023eb469cfc674255e4463a06 104 SUPERFAMILY SSF103481 5 102 2.35E-13 T 28-03-2018 A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 5 254 2.6E-107 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 106 1.4E-28 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 PIRSF PIRSF000915 1 258 4.6E-60 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 230 4.0E-44 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 Pfam PF13242 HAD-hyrolase-like 181 253 3.2E-18 T 28-03-2018 A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 SUPERFAMILY SSF56784 5 255 7.2E-70 T 28-03-2018 IPR023214 HAD-like domain A21D_RS13900 2645085bc4a9af8247c5836e0f3304f3 258 Gene3D G3DSA:3.40.50.1000 1 258 3.7E-33 T 28-03-2018 IPR023214 HAD-like domain A21D_RS09760 a52e44bc5b8102ea5cc77a2b4a125f8d 126 SUPERFAMILY SSF48008 3 114 2.14E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS09760 a52e44bc5b8102ea5cc77a2b4a125f8d 126 Gene3D G3DSA:1.20.120.530 1 119 1.4E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS09760 a52e44bc5b8102ea5cc77a2b4a125f8d 126 Pfam PF07729 FCD domain 3 110 3.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal A21D_RS19490 31fc55adb35b92d99a3e691ae38e82d7 568 Gene3D G3DSA:3.30.2010.10 317 406 1.5E-10 T 28-03-2018 A21D_RS19490 31fc55adb35b92d99a3e691ae38e82d7 568 Pfam PF01435 Peptidase family M48 327 537 6.7E-21 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 SUPERFAMILY SSF55021 377 449 4.28E-19 T 28-03-2018 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 447 8.1E-85 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 Gene3D G3DSA:3.30.70.260 368 449 2.1E-19 T 28-03-2018 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 Gene3D G3DSA:3.40.1160.10 1 280 2.4E-52 T 28-03-2018 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 SUPERFAMILY SSF53633 2 289 1.24E-63 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS16160 e71a64ef787ca997630d245006786f29 449 SUPERFAMILY SSF55021 295 357 1.64E-9 T 28-03-2018 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 Pfam PF00696 Amino acid kinase family 2 275 1.4E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS16160 e71a64ef787ca997630d245006786f29 449 Gene3D G3DSA:3.30.70.260 281 367 7.3E-18 T 28-03-2018 A21D_RS16160 e71a64ef787ca997630d245006786f29 449 PIRSF PIRSF000726 1 449 1.3E-80 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A21D_RS00175 ba0fc86da6b8d3966e11ceb49c353d66 64 Gene3D G3DSA:1.10.260.40 1 63 1.0E-15 T 28-03-2018 A21D_RS00175 ba0fc86da6b8d3966e11ceb49c353d66 64 Pfam PF01381 Helix-turn-helix 4 59 2.8E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS00175 ba0fc86da6b8d3966e11ceb49c353d66 64 SMART SM00530 3 59 7.0E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS00175 ba0fc86da6b8d3966e11ceb49c353d66 64 SUPERFAMILY SSF47413 3 60 2.23E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS06090 2eff119ed213a95444e30f4735d2c76c 257 SMART SM00382 32 220 5.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06090 2eff119ed213a95444e30f4735d2c76c 257 Pfam PF00005 ABC transporter 23 171 4.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06090 2eff119ed213a95444e30f4735d2c76c 257 Gene3D G3DSA:3.40.50.300 1 238 6.5E-65 T 28-03-2018 A21D_RS06090 2eff119ed213a95444e30f4735d2c76c 257 SUPERFAMILY SSF52540 4 224 1.69E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 SUPERFAMILY SSF51338 363 437 9.24E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 SUPERFAMILY SSF51338 4 60 9.24E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 Gene3D G3DSA:3.20.20.140 73 380 9.4E-55 T 28-03-2018 A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 Gene3D G3DSA:2.30.40.10 1 72 5.3E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 SUPERFAMILY SSF51556 60 364 9.68E-86 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS12215 4eaa0652b6ec0061290f3132dcb47f3b 453 Pfam PF01979 Amidohydrolase family 57 411 4.3E-65 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS12910 421c4422261777304878ad8e26f54625 536 Gene3D G3DSA:3.90.350.10 230 497 2.7E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS12910 421c4422261777304878ad8e26f54625 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS12910 421c4422261777304878ad8e26f54625 536 Pfam PF13751 Transposase DDE domain 393 518 2.2E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS08775 421c4422261777304878ad8e26f54625 536 Gene3D G3DSA:3.90.350.10 230 497 2.7E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS08775 421c4422261777304878ad8e26f54625 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS08775 421c4422261777304878ad8e26f54625 536 Pfam PF13751 Transposase DDE domain 393 518 2.2E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS16055 4bc1b80fdb82f911be85539a112cd8f6 170 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 170 2.4E-58 T 28-03-2018 IPR014198 Stage III sporulation protein AB A21D_RS16055 4bc1b80fdb82f911be85539a112cd8f6 170 PIRSF PIRSF021435 1 170 2.5E-49 T 28-03-2018 IPR014198 Stage III sporulation protein AB A21D_RS16055 4bc1b80fdb82f911be85539a112cd8f6 170 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 170 3.6E-50 T 28-03-2018 IPR014198 Stage III sporulation protein AB A21D_RS09340 c5fad2ac1816a96e335c87824c2c2f2f 175 Gene3D G3DSA:1.10.1660.10 61 153 5.5E-6 T 28-03-2018 A21D_RS09340 c5fad2ac1816a96e335c87824c2c2f2f 175 Pfam PF13411 MerR HTH family regulatory protein 6 72 8.5E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09340 c5fad2ac1816a96e335c87824c2c2f2f 175 SUPERFAMILY SSF46955 5 107 1.32E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS09340 c5fad2ac1816a96e335c87824c2c2f2f 175 SMART SM00422 6 75 3.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS09340 c5fad2ac1816a96e335c87824c2c2f2f 175 Gene3D G3DSA:1.10.1660.10 1 60 1.8E-20 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 Gene3D G3DSA:3.90.1150.10 272 395 9.0E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 Pfam PF00155 Aminotransferase class I and II 31 385 4.6E-80 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.7E-17 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.7E-17 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.7E-17 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.7E-17 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.7E-17 T 28-03-2018 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 Gene3D G3DSA:3.40.640.10 44 271 2.6E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS16745 487c7a2fc4388935ad0ef5158d9d5fc6 395 SUPERFAMILY SSF53383 3 389 6.45E-120 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 Gene3D G3DSA:3.40.190.10 217 349 1.7E-27 T 28-03-2018 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 Gene3D G3DSA:3.90.76.10 58 216 7.1E-35 T 28-03-2018 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 SUPERFAMILY SSF53850 41 584 3.8E-116 T 28-03-2018 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 PIRSF PIRSF002741 340 586 1.6E-45 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 PIRSF PIRSF002741 1 327 8.7E-58 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 Gene3D G3DSA:3.10.105.10 350 553 3.2E-48 T 28-03-2018 A21D_RS10805 ec59bc8c375e9f315240c2e2cf0ea840 586 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 495 4.8E-87 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS00485 d5fd7f969499d02940fc249cddccc200 244 SMART SM00382 28 206 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00485 d5fd7f969499d02940fc249cddccc200 244 SUPERFAMILY SSF52540 4 224 1.02E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00485 d5fd7f969499d02940fc249cddccc200 244 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00485 d5fd7f969499d02940fc249cddccc200 244 Pfam PF00005 ABC transporter 19 156 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS00485 d5fd7f969499d02940fc249cddccc200 244 Gene3D G3DSA:3.40.50.300 1 225 1.1E-58 T 28-03-2018 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Pfam PF00175 Oxidoreductase NAD-binding domain 469 575 2.3E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Gene3D G3DSA:2.40.30.10 226 451 1.2E-45 T 28-03-2018 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 537 553 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 506 517 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 560 568 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 277 287 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 468 487 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 398 405 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 431 440 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 493 502 7.9E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PIRSF PIRSF000207 1 611 1.2E-251 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Pfam PF00667 FAD binding domain 238 434 1.1E-27 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 611 1.0E-247 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Gene3D G3DSA:3.40.50.80 465 611 4.1E-35 T 28-03-2018 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00369 Flavodoxin signature 150 160 2.0E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00369 Flavodoxin signature 174 193 2.0E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00369 Flavodoxin signature 118 129 2.0E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 PRINTS PR00369 Flavodoxin signature 70 83 2.0E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 SUPERFAMILY SSF52218 67 215 9.64E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Gene3D G3DSA:3.40.50.360 39 225 3.1E-41 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 Pfam PF00258 Flavodoxin 71 195 1.0E-28 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 SUPERFAMILY SSF63380 237 457 5.96E-59 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS07450 bc4cb978e12b68778735cecb3610fe88 611 SUPERFAMILY SSF52343 456 611 5.63E-47 T 28-03-2018 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 PIRSF PIRSF006092 1 157 7.1E-39 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 80 155 7.4E-22 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 Gene3D G3DSA:1.10.287.180 4 75 4.7E-17 T 28-03-2018 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 Gene3D G3DSA:3.10.50.30 76 156 1.4E-22 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 SUPERFAMILY SSF54534 80 155 1.96E-18 T 28-03-2018 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 1.3E-15 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A21D_RS09205 9efac14e9be5d94bdb3ed36c1b88466b 157 SUPERFAMILY SSF46557 3 76 3.92E-14 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 277 5.5E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 380 565 1.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 SUPERFAMILY SSF161098 12 280 3.53E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 SUPERFAMILY SSF161098 298 565 6.67E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 Gene3D G3DSA:1.10.3720.10 300 571 2.3E-35 T 28-03-2018 A21D_RS05775 9ccf573dde8a40dacb6773f1874bae0b 571 Gene3D G3DSA:1.10.3720.10 15 278 7.3E-30 T 28-03-2018 A21D_RS11585 bf291da8f9da52669a761cb8355c1ee0 130 SUPERFAMILY SSF82784 8 126 7.2E-24 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS11585 bf291da8f9da52669a761cb8355c1ee0 130 Pfam PF02566 OsmC-like protein 25 119 1.5E-17 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS11585 bf291da8f9da52669a761cb8355c1ee0 130 Gene3D G3DSA:3.30.300.20 1 129 3.8E-23 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 Pfam PF01202 Shikimate kinase 18 173 9.2E-41 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 ProSitePatterns PS01128 Shikimate kinase signature. 65 90 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 PRINTS PR01100 Shikimate kinase family signature 36 49 2.7E-16 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 PRINTS PR01100 Shikimate kinase family signature 64 72 2.7E-16 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 PRINTS PR01100 Shikimate kinase family signature 103 120 2.7E-16 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 PRINTS PR01100 Shikimate kinase family signature 12 27 2.7E-16 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 PRINTS PR01100 Shikimate kinase family signature 82 91 2.7E-16 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 SUPERFAMILY SSF52540 10 175 2.92E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 Gene3D G3DSA:3.40.50.300 10 178 8.9E-22 T 28-03-2018 A21D_RS00560 a606ba3b0cb9e47096e43d00d89e9396 185 Hamap MF_00109 Shikimate kinase [aroK]. 9 174 23.272 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A21D_RS00310 e6f2fffd0ff0ec5eb4dad1efeee4a0dd 139 Pfam PF01475 Ferric uptake regulator family 12 128 3.0E-30 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A21D_RS00310 e6f2fffd0ff0ec5eb4dad1efeee4a0dd 139 SUPERFAMILY SSF46785 5 132 4.08E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00310 e6f2fffd0ff0ec5eb4dad1efeee4a0dd 139 Gene3D G3DSA:1.10.10.10 6 91 4.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17725 d4485f4b78c2b2a0519a010305e74d94 92 Gene3D G3DSA:3.30.70.1120 1 91 6.8E-27 T 28-03-2018 A21D_RS17725 d4485f4b78c2b2a0519a010305e74d94 92 Pfam PF04456 Protein of unknown function (DUF503) 2 87 2.7E-27 T 28-03-2018 IPR007546 Protein of unknown function DUF503 A21D_RS17725 d4485f4b78c2b2a0519a010305e74d94 92 SUPERFAMILY SSF103007 1 91 1.15E-26 T 28-03-2018 IPR007546 Protein of unknown function DUF503 A21D_RS06170 76c8d81fd44a13f460fb9a545adb837e 112 Pfam PF07252 Protein of unknown function (DUF1433) 35 85 5.6E-8 T 28-03-2018 IPR009881 Protein of unknown function DUF1433 A21D_RS06170 76c8d81fd44a13f460fb9a545adb837e 112 Gene3D G3DSA:3.10.450.130 30 108 2.4E-12 T 28-03-2018 A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 6 254 33.88 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 8 251 2.7E-89 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 SUPERFAMILY SSF143597 40 240 1.83E-69 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 PIRSF PIRSF004793 6 269 7.8E-92 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 6.2E-44 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A21D_RS05310 ac2d8d87e1b4f24b863f5004acf65462 273 Gene3D G3DSA:3.40.1700.10 111 254 6.2E-38 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A21D_RS00780 ba3073b6ec69d01b80b3456a777ae72d 119 SUPERFAMILY SSF46626 1 117 4.58E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS00780 ba3073b6ec69d01b80b3456a777ae72d 119 PIRSF PIRSF000025 1 119 1.5E-34 T 28-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A21D_RS00780 ba3073b6ec69d01b80b3456a777ae72d 119 Gene3D G3DSA:1.10.760.10 21 118 1.0E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS00780 ba3073b6ec69d01b80b3456a777ae72d 119 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 47 114 1.6E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.0E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.0E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 Pfam PF05573 NosL 122 175 3.5E-7 T 28-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 SUPERFAMILY SSF160387 83 186 3.4E-20 T 28-03-2018 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 Gene3D G3DSA:1.10.10.10 1 69 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 SUPERFAMILY SSF46785 5 65 2.96E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 SMART SM00420 6 58 1.2E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS19180 d57bb90adca85e6f89539a92afe61583 190 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.7E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 SUPERFAMILY SSF63418 1 98 4.32E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Gene3D G3DSA:3.90.190.20 338 491 3.4E-50 T 28-03-2018 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 417 1.3E-24 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 SUPERFAMILY SSF53623 98 332 2.88E-74 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 SUPERFAMILY SSF53244 333 485 1.27E-48 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 485 36.225 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Gene3D G3DSA:3.40.1390.10 1 97 9.1E-28 T 28-03-2018 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Pfam PF01225 Mur ligase family, catalytic domain 24 95 2.7E-14 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Gene3D G3DSA:3.40.1190.10 98 337 1.2E-60 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 Pfam PF08245 Mur ligase middle domain 107 312 1.0E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A21D_RS18405 511c1c20e6a64569a80512c050c8be4d 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 485 5.4E-170 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 PIRSF PIRSF000124 1 388 8.4E-136 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 PIRSF PIRSF500134 1 379 8.7E-119 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Gene3D G3DSA:3.40.50.720 288 388 2.3E-18 T 28-03-2018 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 168 1.2E-36 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 378 6.6E-108 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Gene3D G3DSA:1.20.5.100 194 211 5.4E-15 T 28-03-2018 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Gene3D G3DSA:1.10.1040.10 212 287 6.1E-28 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 SUPERFAMILY SSF48179 191 287 1.7E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Gene3D G3DSA:3.40.50.720 1 193 3.7E-50 T 28-03-2018 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 374 5.0E-10 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 SUPERFAMILY SSF52413 283 388 4.97E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 SUPERFAMILY SSF51735 1 194 4.77E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 8.0E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS02600 199cda3ce56246f751ffa775b7018c4c 388 SMART SM00984 300 387 1.2E-14 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A21D_RS04475 76b16a8eb2bac263c0c47e0e941a97a8 404 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 74 393 5.0E-117 T 28-03-2018 IPR014225 Sporulation stage II, protein D firmicutes A21D_RS04475 76b16a8eb2bac263c0c47e0e941a97a8 404 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 135 392 2.8E-71 T 28-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 A21D_RS04475 76b16a8eb2bac263c0c47e0e941a97a8 404 Pfam PF08486 Stage II sporulation protein 131 233 1.0E-25 T 28-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal A21D_RS08500 74bb4d03f372540b3f0ee038bdf265bc 208 Gene3D G3DSA:3.20.20.70 1 208 5.2E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08500 74bb4d03f372540b3f0ee038bdf265bc 208 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 205 2.1E-53 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A21D_RS08500 74bb4d03f372540b3f0ee038bdf265bc 208 Pfam PF01081 KDPG and KHG aldolase 5 196 1.1E-47 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A21D_RS08500 74bb4d03f372540b3f0ee038bdf265bc 208 SUPERFAMILY SSF51569 3 206 2.93E-59 T 28-03-2018 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 Gene3D G3DSA:3.20.20.210 4 344 3.4E-91 T 28-03-2018 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 46.148 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 SUPERFAMILY SSF51726 4 343 2.49E-100 T 28-03-2018 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 340 1.8E-124 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 1.6E-118 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A21D_RS13225 938926d80a6a4298918b076191de32aa 346 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A21D_RS12780 9357a1302330a60504801669c64fa281 731 Gene3D G3DSA:3.40.1710.10 48 546 1.5E-23 T 28-03-2018 A21D_RS12780 9357a1302330a60504801669c64fa281 731 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 169 2.1E-46 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal A21D_RS12780 9357a1302330a60504801669c64fa281 731 SUPERFAMILY SSF58104 170 397 3.14E-5 T 28-03-2018 A21D_RS12780 9357a1302330a60504801669c64fa281 731 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 512 710 4.9E-52 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal A21D_RS12780 9357a1302330a60504801669c64fa281 731 Pfam PF12698 ABC-2 family transporter protein 22 165 1.1E-10 T 28-03-2018 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 Gene3D G3DSA:1.10.10.10 1 97 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 SMART SM00418 18 99 6.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 SUPERFAMILY SSF46785 8 94 1.63E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 2.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 53 2.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS14865 ec5d2648573b322f8b73e901ca7cb5b5 103 Pfam PF01022 Bacterial regulatory protein, arsR family 25 72 1.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS04885 52ae0c0c3e7e76e35c11211984f7922d 296 Gene3D G3DSA:1.20.58.370 1 41 9.1E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A21D_RS04885 52ae0c0c3e7e76e35c11211984f7922d 296 SUPERFAMILY SSF160964 7 56 5.89E-5 T 28-03-2018 A21D_RS04885 52ae0c0c3e7e76e35c11211984f7922d 296 Gene3D G3DSA:1.10.3720.10 62 294 6.6E-46 T 28-03-2018 A21D_RS04885 52ae0c0c3e7e76e35c11211984f7922d 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 286 1.7E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04885 52ae0c0c3e7e76e35c11211984f7922d 296 SUPERFAMILY SSF161098 57 285 8.11E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS17055 fa9b70d27596d1fda0cef7c4ad7809d8 138 Gene3D G3DSA:3.40.50.720 15 136 5.9E-33 T 28-03-2018 A21D_RS17055 fa9b70d27596d1fda0cef7c4ad7809d8 138 Pfam PF13380 CoA binding domain 19 133 2.8E-39 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS17055 fa9b70d27596d1fda0cef7c4ad7809d8 138 SMART SM00881 15 108 1.3E-20 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS17055 fa9b70d27596d1fda0cef7c4ad7809d8 138 SUPERFAMILY SSF51735 2 134 4.68E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 SMART SM00283 154 429 6.6E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 SMART SM00304 72 125 3.0E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 231 382 1.2E-36 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 Pfam PF00672 HAMP domain 72 121 4.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 Gene3D G3DSA:1.10.287.950 78 187 6.9E-7 T 28-03-2018 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 Gene3D G3DSA:1.10.287.950 188 431 4.4E-49 T 28-03-2018 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 SUPERFAMILY SSF58104 160 428 1.83E-63 T 28-03-2018 A21D_RS04610 3e4e93da6616f418512545201ccd594d 431 SUPERFAMILY SSF58104 94 127 1.83E-63 T 28-03-2018 A21D_RS14100 4fb8fe61d1d10dd78136c24bafcc760c 64 Gene3D G3DSA:1.10.260.40 1 63 1.4E-16 T 28-03-2018 A21D_RS14100 4fb8fe61d1d10dd78136c24bafcc760c 64 SMART SM00530 4 59 9.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS14100 4fb8fe61d1d10dd78136c24bafcc760c 64 Pfam PF01381 Helix-turn-helix 5 59 8.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS14100 4fb8fe61d1d10dd78136c24bafcc760c 64 SUPERFAMILY SSF47413 2 61 7.6E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS08470 a9712b101cb652a02c66009e61fc7e0a 317 Pfam PF12679 ABC-2 family transporter protein 7 314 1.5E-22 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 93 107 1.0E-6 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 180 1.0E-6 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 192 203 1.0E-6 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 145 1.0E-6 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 Gene3D G3DSA:3.90.226.10 253 510 1.4E-71 T 28-03-2018 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 SUPERFAMILY SSF52096 5 251 3.65E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS11950 6249a0562d72401811096bc125efecc5 514 SUPERFAMILY SSF52096 265 514 2.41E-87 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS11950 6249a0562d72401811096bc125efecc5 514 Gene3D G3DSA:3.90.226.10 1 252 9.1E-74 T 28-03-2018 A21D_RS11950 6249a0562d72401811096bc125efecc5 514 Pfam PF01039 Carboxyl transferase domain 28 512 7.0E-184 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 47 4.9E-20 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 8.1E-7 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 8.1E-7 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 8.1E-7 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 Pfam PF02416 mttA/Hcf106 family 5 57 1.4E-22 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A21D_RS14955 62dad940f961848fe849e3393e8292a6 59 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 59 18.188 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A21D_RS08305 1b6f72fdac597138de2983edb41aea06 289 Pfam PF00950 ABC 3 transport family 12 275 2.0E-68 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A21D_RS08305 1b6f72fdac597138de2983edb41aea06 289 SUPERFAMILY SSF81345 15 273 4.05E-29 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS08305 1b6f72fdac597138de2983edb41aea06 289 Gene3D G3DSA:1.10.3470.10 2 283 4.0E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS01210 b9b81d9b7d6e129084345a8e047d09fd 205 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 7 203 2.2E-64 T 28-03-2018 IPR014205 Sporulation protein YtaF A21D_RS01210 b9b81d9b7d6e129084345a8e047d09fd 205 Pfam PF02659 Putative manganese efflux pump 121 201 1.5E-8 T 28-03-2018 IPR003810 Putative manganese efflux pump A21D_RS01210 b9b81d9b7d6e129084345a8e047d09fd 205 Pfam PF02659 Putative manganese efflux pump 5 80 1.6E-7 T 28-03-2018 IPR003810 Putative manganese efflux pump A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 SUPERFAMILY SSF88946 3 79 1.88E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 Pfam PF04542 Sigma-70 region 2 7 73 9.6E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 Pfam PF08281 Sigma-70, region 4 117 168 9.1E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 SUPERFAMILY SSF88659 111 172 4.3E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 Gene3D G3DSA:1.10.1740.10 1 71 8.2E-16 T 28-03-2018 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 170 2.7E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09520 15323dda9f7001e2a67778e70b752170 178 Gene3D G3DSA:1.10.10.10 107 174 1.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02595 51f567c2ae7b8ddc14a7a0714207472e 305 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 85 226 7.9E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS02595 51f567c2ae7b8ddc14a7a0714207472e 305 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 84 227 6.1E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS09820 f2b60fa763c2327fb965f343d4703726 90 Pfam PF06803 Protein of unknown function (DUF1232) 37 70 5.9E-8 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 A21D_RS09820 f2b60fa763c2327fb965f343d4703726 90 PIRSF PIRSF029962 1 90 4.7E-35 T 28-03-2018 IPR016941 Uncharacterised conserved protein UCP029962 A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 SMART SM00881 79 178 4.3E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 207 37.731 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 SUPERFAMILY SSF51735 82 205 3.35E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 SUPERFAMILY SSF46785 7 78 1.16E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 Pfam PF02629 CoA binding domain 81 176 1.8E-27 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 Gene3D G3DSA:1.10.10.10 4 70 8.6E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 Gene3D G3DSA:3.40.50.720 71 185 8.5E-16 T 28-03-2018 A21D_RS10205 1165ac2e024e8e2611b279ed1c69737c 220 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 2.2E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 A21D_RS02480 995a595248ca2090fa03098c3b90c306 114 Pfam PF01381 Helix-turn-helix 12 66 1.1E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS02480 995a595248ca2090fa03098c3b90c306 114 Gene3D G3DSA:1.10.260.40 1 114 5.5E-25 T 28-03-2018 A21D_RS02480 995a595248ca2090fa03098c3b90c306 114 SUPERFAMILY SSF47413 7 69 1.29E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS02480 995a595248ca2090fa03098c3b90c306 114 SMART SM00530 11 66 6.3E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS16015 947938f7d674fb9fb8185f514303fc72 123 SUPERFAMILY SSF52821 7 118 8.64E-34 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS16015 947938f7d674fb9fb8185f514303fc72 123 Pfam PF00581 Rhodanese-like domain 40 117 1.2E-21 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS16015 947938f7d674fb9fb8185f514303fc72 123 Gene3D G3DSA:3.40.250.10 19 121 1.3E-29 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS16015 947938f7d674fb9fb8185f514303fc72 123 SMART SM00450 27 122 5.5E-30 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS10230 408c773216701c311deb37f7b8578db4 400 Pfam PF00589 Phage integrase family 181 376 3.1E-26 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS10230 408c773216701c311deb37f7b8578db4 400 Gene3D G3DSA:1.10.443.10 181 385 6.7E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A21D_RS10230 408c773216701c311deb37f7b8578db4 400 SUPERFAMILY SSF56349 67 383 2.06E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A21D_RS10230 408c773216701c311deb37f7b8578db4 400 Gene3D G3DSA:1.10.150.130 63 173 2.0E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS13870 1b1970cacf694ee7cecb1052879fcc94 307 SUPERFAMILY SSF51261 98 295 1.1E-36 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS13870 1b1970cacf694ee7cecb1052879fcc94 307 Gene3D G3DSA:1.10.530.10 5 163 5.4E-10 T 28-03-2018 A21D_RS13870 1b1970cacf694ee7cecb1052879fcc94 307 Gene3D G3DSA:2.70.70.10 164 307 2.7E-27 T 28-03-2018 A21D_RS13870 1b1970cacf694ee7cecb1052879fcc94 307 Pfam PF01551 Peptidase family M23 184 282 4.8E-20 T 28-03-2018 IPR016047 Peptidase M23 A21D_RS14370 fc6c6250632103187307c9c13d34ad30 217 PIRSF PIRSF021278 2 210 1.1E-78 T 28-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 A21D_RS14370 fc6c6250632103187307c9c13d34ad30 217 Pfam PF00583 Acetyltransferase (GNAT) family 47 119 1.7E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS14370 fc6c6250632103187307c9c13d34ad30 217 SUPERFAMILY SSF55729 32 134 2.48E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS14370 fc6c6250632103187307c9c13d34ad30 217 Gene3D G3DSA:3.40.630.30 1 211 3.0E-50 T 28-03-2018 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 3.7E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 3.7E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 3.7E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 3.7E-13 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 PIRSF PIRSF006648 2 247 2.2E-19 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A21D_RS04935 664ebbb70a7b7eb9f594e00fb571f309 247 Pfam PF01061 ABC-2 type transporter 4 210 3.5E-26 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 Pfam PF00005 ABC transporter 31 180 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 Gene3D G3DSA:3.40.50.300 1 296 9.1E-74 T 28-03-2018 A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 272 1.8E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 SUPERFAMILY SSF52540 3 252 5.32E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 SMART SM00382 39 230 5.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS07035 003635edb6fd01356347313b2ff5318f 310 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07520 b18170ab786acd240f83566db2521030 509 SUPERFAMILY SSF56601 47 505 1.73E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS07520 b18170ab786acd240f83566db2521030 509 Gene3D G3DSA:3.40.710.10 45 509 6.0E-40 T 28-03-2018 A21D_RS07520 b18170ab786acd240f83566db2521030 509 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 77 484 2.6E-122 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 49 504 4.8E-127 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 89 108 4.6E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 379 393 4.6E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 461 474 4.6E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 322 344 4.6E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS07520 b18170ab786acd240f83566db2521030 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 394 408 4.6E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS17995 7e3cedb5b36299e5300299da72a9e192 310 Gene3D G3DSA:3.40.50.450 115 271 5.4E-40 T 28-03-2018 A21D_RS17995 7e3cedb5b36299e5300299da72a9e192 310 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 289 1.7E-75 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A21D_RS17995 7e3cedb5b36299e5300299da72a9e192 310 SUPERFAMILY SSF102405 82 288 1.3E-35 T 28-03-2018 A21D_RS17995 7e3cedb5b36299e5300299da72a9e192 310 Pfam PF02481 DNA recombination-mediator protein A 74 280 1.5E-79 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A21D_RS01730 273b377d9a8fd888372aa827dcada761 199 SUPERFAMILY SSF46689 8 79 2.57E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS01730 273b377d9a8fd888372aa827dcada761 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 3.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS01730 273b377d9a8fd888372aa827dcada761 199 Gene3D G3DSA:1.10.10.60 13 52 1.2E-8 T 28-03-2018 A21D_RS01730 273b377d9a8fd888372aa827dcada761 199 Gene3D G3DSA:1.10.10.60 53 137 2.2E-5 T 28-03-2018 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 SUPERFAMILY SSF48179 183 328 1.6E-70 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 4.8E-67 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 6.3E-76 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 6.0E-140 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.943 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 Gene3D G3DSA:1.10.1040.10 54 330 2.7E-117 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 SUPERFAMILY SSF51735 3 182 1.15E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 PIRSF PIRSF000116 1 206 7.0E-39 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 PIRSF PIRSF000116 201 329 1.1E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A21D_RS01440 d62c13bfc981da8a7d3a7228c42d78b2 347 Gene3D G3DSA:3.40.50.720 13 48 0.0029 T 28-03-2018 A21D_RS01385 565df801e43781e24e5ccf1fc61ec49e 449 SUPERFAMILY SSF53850 20 440 1.59E-56 T 28-03-2018 A21D_RS01385 565df801e43781e24e5ccf1fc61ec49e 449 Gene3D G3DSA:3.40.190.10 183 385 1.8E-37 T 28-03-2018 A21D_RS01385 565df801e43781e24e5ccf1fc61ec49e 449 Gene3D G3DSA:3.40.190.10 42 182 2.0E-13 T 28-03-2018 A21D_RS01385 565df801e43781e24e5ccf1fc61ec49e 449 TIGRFAM TIGR03850 bind_CPR_0540: carbohydrate ABC transporter substrate-binding protein, CPR_0540 family 6 445 4.1E-201 T 28-03-2018 IPR022387 Carbohydrate ABC transporter substrate-binding, CPR0540 A21D_RS01385 565df801e43781e24e5ccf1fc61ec49e 449 Pfam PF13416 Bacterial extracellular solute-binding protein 61 367 3.6E-33 T 28-03-2018 A21D_RS12935 42873f89d12a96d30cf0983e63b0793b 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 5 29 2.7E-14 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS12935 42873f89d12a96d30cf0983e63b0793b 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 29 1.8E-12 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS05470 e49f96ed566aa80575e59cdf949a1354 529 Gene3D G3DSA:1.20.120.20 324 516 4.3E-7 T 28-03-2018 A21D_RS05470 e49f96ed566aa80575e59cdf949a1354 529 Gene3D G3DSA:1.10.287.700 133 242 6.4E-4 T 28-03-2018 A21D_RS05470 e49f96ed566aa80575e59cdf949a1354 529 Gene3D G3DSA:1.10.287.700 243 323 9.3E-14 T 28-03-2018 A21D_RS05470 e49f96ed566aa80575e59cdf949a1354 529 Gene3D G3DSA:1.10.287.850 9 72 0.03 T 28-03-2018 A21D_RS11705 3b3ef5bf42050333fc465004e2b3779e 59 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 13 57 1.0E-12 T 28-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A21D_RS11705 3b3ef5bf42050333fc465004e2b3779e 59 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 13 58 1.8E-11 T 28-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A21D_RS06935 7df5914482566ca444d1be5b83bf7c32 144 Pfam PF02082 Transcriptional regulator 1 82 1.1E-22 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A21D_RS06935 7df5914482566ca444d1be5b83bf7c32 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 2.6E-34 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A21D_RS06935 7df5914482566ca444d1be5b83bf7c32 144 Gene3D G3DSA:1.10.10.10 1 142 2.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06935 7df5914482566ca444d1be5b83bf7c32 144 SUPERFAMILY SSF46785 3 135 3.03E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09030 fc1f6e2fab67df02a10bb354976fcd99 308 Pfam PF06207 Protein of unknown function (DUF1002) 48 266 1.9E-71 T 28-03-2018 IPR009343 Protein of unknown function DUF1002 A21D_RS09030 fc1f6e2fab67df02a10bb354976fcd99 308 Gene3D G3DSA:1.20.5.1230 116 308 1.6E-5 T 28-03-2018 A21D_RS04955 5273f47016036de081ed4803f2df6721 292 Pfam PF00005 ABC transporter 24 173 7.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04955 5273f47016036de081ed4803f2df6721 292 SMART SM00382 33 222 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04955 5273f47016036de081ed4803f2df6721 292 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04955 5273f47016036de081ed4803f2df6721 292 SUPERFAMILY SSF52540 3 236 1.11E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04955 5273f47016036de081ed4803f2df6721 292 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 8.2E-102 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 A21D_RS04955 5273f47016036de081ed4803f2df6721 292 Gene3D G3DSA:3.40.50.300 1 280 3.6E-64 T 28-03-2018 A21D_RS10860 23091cf5dbee1b1c7dd0860acc59ed12 731 SMART SM00460 471 545 3.9E-18 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS10860 23091cf5dbee1b1c7dd0860acc59ed12 731 Pfam PF01841 Transglutaminase-like superfamily 422 543 8.1E-26 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS10860 23091cf5dbee1b1c7dd0860acc59ed12 731 SUPERFAMILY SSF54001 396 549 3.64E-42 T 28-03-2018 A21D_RS10860 23091cf5dbee1b1c7dd0860acc59ed12 731 Gene3D G3DSA:3.90.260.10 418 577 2.1E-26 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS16505 7ccb8e4b2ce5d5f8ad438252064ff743 229 PIRSF PIRSF016933 1 219 1.5E-76 T 28-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A21D_RS16505 7ccb8e4b2ce5d5f8ad438252064ff743 229 Pfam PF13367 Protease prsW family 27 200 2.6E-29 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 A21D_RS04030 83daf2f64892482186f1cfc57a10d7ae 221 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 87 115 1.1E-9 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A21D_RS04030 83daf2f64892482186f1cfc57a10d7ae 221 SUPERFAMILY SSF57716 89 117 4.56E-7 T 28-03-2018 A21D_RS04030 83daf2f64892482186f1cfc57a10d7ae 221 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 162 5.9E-58 T 28-03-2018 IPR014240 Regulatory protein, YteA family A21D_RS04030 83daf2f64892482186f1cfc57a10d7ae 221 SUPERFAMILY SSF109635 2 88 1.57E-12 T 28-03-2018 A21D_RS00480 046e6765cb924fdacb21fb40729cfbaa 259 SUPERFAMILY SSF51556 5 257 1.05E-54 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS00480 046e6765cb924fdacb21fb40729cfbaa 259 Pfam PF01026 TatD related DNase 6 256 5.2E-52 T 28-03-2018 IPR001130 TatD family GO:0016788 A21D_RS00480 046e6765cb924fdacb21fb40729cfbaa 259 Gene3D G3DSA:3.20.20.140 3 259 2.1E-57 T 28-03-2018 A21D_RS00480 046e6765cb924fdacb21fb40729cfbaa 259 PIRSF PIRSF005902 1 259 1.2E-53 T 28-03-2018 IPR001130 TatD family GO:0016788 A21D_RS00480 046e6765cb924fdacb21fb40729cfbaa 259 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 5 13 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A21D_RS06165 dc0b241384b64c8544b35d98a0f203b9 122 Gene3D G3DSA:3.10.450.130 32 122 1.7E-13 T 28-03-2018 A21D_RS06165 dc0b241384b64c8544b35d98a0f203b9 122 Pfam PF07252 Protein of unknown function (DUF1433) 38 95 9.2E-10 T 28-03-2018 IPR009881 Protein of unknown function DUF1433 A21D_RS17470 d9be3cd8d4bf7ebc3d46ee30c8535c6d 83 Pfam PF12652 CotJB protein 7 82 7.9E-29 T 28-03-2018 IPR024207 Spore coat assembly protein CotJB, domain A21D_RS17470 d9be3cd8d4bf7ebc3d46ee30c8535c6d 83 PIRSF PIRSF010606 1 83 2.6E-37 T 28-03-2018 IPR016571 Spore coat assembly protein CotJB A21D_RS08385 ee11cdcec83bccaf730c2f1fae3772ba 247 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 224 1.9E-54 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A21D_RS16450 1021b308bba238829f99657d06cc9d9c 144 Pfam PF14478 Domain of unknown function (DUF4430) 74 141 5.5E-22 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 A21D_RS16450 1021b308bba238829f99657d06cc9d9c 144 Gene3D G3DSA:3.40.190.10 1 144 1.3E-5 T 28-03-2018 A21D_RS08660 681a1dba3c098fe661099e880b5d47d4 305 SUPERFAMILY SSF51658 45 262 9.26E-10 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A21D_RS08660 681a1dba3c098fe661099e880b5d47d4 305 Gene3D G3DSA:3.20.20.150 25 304 2.1E-12 T 28-03-2018 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 SUPERFAMILY SSF53850 191 289 2.47E-25 T 28-03-2018 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 192 289 2.0E-19 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 28 168 2.0E-33 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 Gene3D G3DSA:3.40.190.10 26 181 1.1E-36 T 28-03-2018 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 Gene3D G3DSA:3.40.190.10 187 284 1.3E-14 T 28-03-2018 A21D_RS13115 8c70ac3544578f3df79568aaf0042b9c 290 SUPERFAMILY SSF53850 27 184 7.96E-45 T 28-03-2018 A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 SUPERFAMILY SSF52335 1 131 5.1E-53 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 123 4.4E-60 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 PIRSF PIRSF006614 1 139 9.7E-62 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 35.753 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 SMART SM00851 14 107 9.7E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 Pfam PF02142 MGS-like domain 15 107 1.7E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 Gene3D G3DSA:3.40.50.1380 1 137 5.6E-37 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A21D_RS16710 e6aba86f2dcb888dfb9fce7ba5674c8b 139 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A21D_RS09570 2e8b3da4e8ae01957ab24de30d02ecea 260 SUPERFAMILY SSF56281 9 228 3.78E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS09570 2e8b3da4e8ae01957ab24de30d02ecea 260 Gene3D G3DSA:3.60.15.10 2 242 5.1E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS09570 2e8b3da4e8ae01957ab24de30d02ecea 260 Pfam PF00753 Metallo-beta-lactamase superfamily 28 182 4.2E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS09570 2e8b3da4e8ae01957ab24de30d02ecea 260 SMART SM00849 27 218 3.5E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 SUPERFAMILY SSF53901 3 269 8.77E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 Gene3D G3DSA:3.40.47.10 266 390 1.1E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 5.0E-141 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 PIRSF PIRSF000429 1 394 2.1E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 SUPERFAMILY SSF53901 272 392 2.96E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 Gene3D G3DSA:3.40.47.10 1 265 5.6E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 Pfam PF02803 Thiolase, C-terminal domain 272 391 6.5E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A21D_RS04730 7f0cd4503d9079071f1b0228bc4d19e2 395 Pfam PF00108 Thiolase, N-terminal domain 5 262 1.6E-96 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A21D_RS08740 1e6923158c95c676da754f3a518bb770 53 Gene3D G3DSA:2.10.110.10 7 53 0.0022 T 28-03-2018 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 61 79 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 SMART SM00418 37 116 1.4E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 9.9E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 9.9E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 9.9E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 9.9E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 SUPERFAMILY SSF46785 28 113 3.66E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 Gene3D G3DSA:1.10.10.10 6 124 5.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03980 6597b9e11486b33d6c1fc7ce3d5bd8ea 127 Pfam PF01022 Bacterial regulatory protein, arsR family 44 89 1.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Gene3D G3DSA:3.10.20.30 389 462 1.2E-25 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SUPERFAMILY SSF109604 8 196 6.59E-78 T 28-03-2018 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SUPERFAMILY SSF81301 185 399 1.34E-68 T 28-03-2018 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SMART SM00471 46 158 2.3E-10 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Gene3D G3DSA:3.30.70.260 653 733 1.9E-13 T 28-03-2018 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SUPERFAMILY SSF55021 655 731 6.66E-12 T 28-03-2018 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SUPERFAMILY SSF81271 382 454 3.11E-24 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 4.8E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Pfam PF13328 HD domain 31 180 6.5E-53 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 SMART SM00954 240 350 9.0E-71 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Gene3D G3DSA:3.30.460.10 193 330 1.8E-47 T 28-03-2018 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Pfam PF13291 ACT domain 653 730 2.3E-21 T 28-03-2018 IPR002912 ACT domain A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 730 2.1E-261 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 A21D_RS15335 55570e68cf47c2ebfae771cafce2b88f 733 Pfam PF02824 TGS domain 395 454 2.2E-22 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A21D_RS03680 e7dc0b02e5f7be46fe70ee57cfaa5e8f 139 Gene3D G3DSA:1.20.5.110 88 132 4.3E-4 T 28-03-2018 A21D_RS03680 e7dc0b02e5f7be46fe70ee57cfaa5e8f 139 ProDom PD338809 BH2346 YXIB BH4015 BH0976 PREFOLDIN 18 121 6.0E-6 T 28-03-2018 A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 Gene3D G3DSA:4.10.960.10 58 164 2.2E-33 T 28-03-2018 A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 202 2.3E-85 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 38.332 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 SUPERFAMILY SSF50447 1 207 2.38E-80 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A21D_RS06375 5aedff97745c8597fe1c2862879eb571 209 Pfam PF00297 Ribosomal protein L3 98 181 1.2E-16 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15250 ccd78a75938c184f713a884e41d7da20 247 Gene3D G3DSA:3.40.50.620 1 247 1.9E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS15250 ccd78a75938c184f713a884e41d7da20 247 SUPERFAMILY SSF52402 2 242 3.26E-71 T 28-03-2018 A21D_RS15250 ccd78a75938c184f713a884e41d7da20 247 TIGRFAM TIGR00552 nadE: NAD+ synthetase 3 241 4.7E-78 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A21D_RS15250 ccd78a75938c184f713a884e41d7da20 247 Pfam PF02540 NAD synthase 5 238 6.5E-73 T 28-03-2018 IPR022310 NAD/GMP synthase A21D_RS15250 ccd78a75938c184f713a884e41d7da20 247 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 1 243 30.265 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A21D_RS09325 a19147b2f1356586de01579e5101fe3b 386 SUPERFAMILY SSF51419 34 268 6.28E-21 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS09325 a19147b2f1356586de01579e5101fe3b 386 Gene3D G3DSA:3.20.20.10 35 259 6.8E-24 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS09325 a19147b2f1356586de01579e5101fe3b 386 Pfam PF01168 Alanine racemase, N-terminal domain 33 264 2.4E-17 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 SUPERFAMILY SSF53697 95 254 1.27E-23 T 28-03-2018 A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 Pfam PF01380 SIS domain 121 246 8.2E-16 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 Gene3D G3DSA:3.40.50.10490 80 254 1.0E-20 T 28-03-2018 A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 SUPERFAMILY SSF46689 11 83 2.51E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 Gene3D G3DSA:1.10.10.10 7 79 8.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09405 52f29d35479a6263f602c78d801ec6b5 280 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 73 1.2E-8 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 SUPERFAMILY SSF81333 3 69 4.05E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 1.4E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 1.4E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 1.4E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 69 9.9E-24 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 Gene3D G3DSA:1.20.20.10 1 70 8.7E-20 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 Pfam PF00137 ATP synthase subunit C 4 66 1.4E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A21D_RS04560 a9b923ef4c4833348bf5858959a0fca8 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.927 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Gene3D G3DSA:2.40.10.170 1 81 3.0E-31 T 28-03-2018 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 468 58.078 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Gene3D G3DSA:3.40.50.300 82 355 1.2E-92 T 28-03-2018 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 468 5.4E-258 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 350 6.8E-69 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 SUPERFAMILY SSF52540 83 355 4.67E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 SMART SM00382 149 334 2.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Gene3D G3DSA:1.10.1140.10 356 466 1.2E-42 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 79 2.6E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 SUPERFAMILY SSF47917 353 468 9.94E-53 T 28-03-2018 A21D_RS04535 f1080d29d4c5f89273d426254dd2d3e3 469 SUPERFAMILY SSF50615 1 81 1.2E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A21D_RS13050 2acdb7c958aae68e907eb8613bb00c95 407 SUPERFAMILY SSF56300 5 267 6.53E-50 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS13050 2acdb7c958aae68e907eb8613bb00c95 407 Pfam PF00149 Calcineurin-like phosphoesterase 6 204 7.1E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS13050 2acdb7c958aae68e907eb8613bb00c95 407 PIRSF PIRSF033091 2 407 3.2E-126 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type A21D_RS13050 2acdb7c958aae68e907eb8613bb00c95 407 Gene3D G3DSA:3.60.21.10 2 79 2.8E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS13050 2acdb7c958aae68e907eb8613bb00c95 407 Gene3D G3DSA:3.60.21.10 80 254 3.2E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS14155 166752375d17768d9698b52f403a305b 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 3.7E-164 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A21D_RS14155 166752375d17768d9698b52f403a305b 632 SUPERFAMILY SSF56235 1 224 5.58E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS14155 166752375d17768d9698b52f403a305b 632 Gene3D G3DSA:3.60.20.10 1 222 3.4E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS14155 166752375d17768d9698b52f403a305b 632 SUPERFAMILY SSF52402 467 605 9.7E-86 T 28-03-2018 A21D_RS14155 166752375d17768d9698b52f403a305b 632 SUPERFAMILY SSF52402 230 380 9.7E-86 T 28-03-2018 A21D_RS14155 166752375d17768d9698b52f403a305b 632 Pfam PF00733 Asparagine synthase 241 610 2.6E-110 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A21D_RS14155 166752375d17768d9698b52f403a305b 632 Pfam PF13537 Glutamine amidotransferase domain 51 167 7.1E-42 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A21D_RS14155 166752375d17768d9698b52f403a305b 632 PIRSF PIRSF001589 1 627 3.4E-192 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A21D_RS14155 166752375d17768d9698b52f403a305b 632 Gene3D G3DSA:3.40.50.620 223 617 3.7E-82 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS11510 211c993e092e87ab9b6b6c711349b514 482 Gene3D G3DSA:3.40.605.10 2 268 3.1E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11510 211c993e092e87ab9b6b6c711349b514 482 Pfam PF00171 Aldehyde dehydrogenase family 26 476 2.8E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11510 211c993e092e87ab9b6b6c711349b514 482 SUPERFAMILY SSF53720 5 478 7.72E-165 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS11510 211c993e092e87ab9b6b6c711349b514 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS11510 211c993e092e87ab9b6b6c711349b514 482 Gene3D G3DSA:3.40.309.10 269 463 1.2E-72 T 28-03-2018 A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 Gene3D G3DSA:3.10.180.10 65 223 8.4E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 Gene3D G3DSA:3.10.180.10 224 283 0.041 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 ProSitePatterns PS00934 Glyoxalase I signature 1. 172 193 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 SUPERFAMILY SSF54593 170 281 1.05E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 Gene3D G3DSA:3.10.180.10 4 64 3.5E-4 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 SUPERFAMILY SSF54593 8 159 2.55E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 170 280 1.6E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS03785 840f8986bc5082aba7afeb1226ebc807 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 125 2.8E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS17880 36b945464e51d24136e6730ecea477fc 120 Gene3D G3DSA:3.40.50.2300 2 120 2.4E-38 T 28-03-2018 A21D_RS17880 36b945464e51d24136e6730ecea477fc 120 SMART SM00448 3 115 1.1E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17880 36b945464e51d24136e6730ecea477fc 120 SUPERFAMILY SSF52172 3 120 3.13E-39 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS17880 36b945464e51d24136e6730ecea477fc 120 Pfam PF00072 Response regulator receiver domain 5 116 1.8E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17820 1bf685fde15914998e3d0c77429e9464 208 SUPERFAMILY SSF103039 5 204 7.85E-52 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17820 1bf685fde15914998e3d0c77429e9464 208 Gene3D G3DSA:3.40.1550.10 3 204 4.1E-54 T 28-03-2018 IPR028976 CheC-like domain A21D_RS17820 1bf685fde15914998e3d0c77429e9464 208 Pfam PF04509 CheC-like family 9 46 7.3E-16 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 A21D_RS17820 1bf685fde15914998e3d0c77429e9464 208 Pfam PF04509 CheC-like family 109 144 5.0E-8 T 28-03-2018 IPR007597 CheC-like protein GO:0016787 A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 SUPERFAMILY SSF55729 7 171 2.4E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 Pfam PF00266 Aminotransferase class-V 213 391 8.6E-14 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 Gene3D G3DSA:3.40.630.30 4 201 3.3E-22 T 28-03-2018 A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 Gene3D G3DSA:3.90.1150.10 434 533 4.1E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 SUPERFAMILY SSF53383 192 528 6.05E-55 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 Gene3D G3DSA:3.40.640.10 202 433 2.8E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS19455 c9073c0cd732a29dc0e561897e62e90a 540 Pfam PF13673 Acetyltransferase (GNAT) domain 40 168 8.5E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS02570 0eaab7e3cf14d1985a2294a0169083ff 320 Gene3D G3DSA:1.10.10.10 1 64 2.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02570 0eaab7e3cf14d1985a2294a0169083ff 320 SUPERFAMILY SSF46785 4 60 2.29E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02570 0eaab7e3cf14d1985a2294a0169083ff 320 Pfam PF08279 HTH domain 8 60 1.4E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS02570 0eaab7e3cf14d1985a2294a0169083ff 320 Pfam PF13280 WYL domain 139 314 6.0E-27 T 28-03-2018 IPR026881 WYL domain A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.2E-28 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 SUPERFAMILY SSF53067 5 194 1.3E-58 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 4.2E-123 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 SUPERFAMILY SSF53067 197 367 1.02E-37 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 425 29.721 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Pfam PF14450 Cell division protein FtsA 9 187 6.3E-11 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Pfam PF14450 Cell division protein FtsA 205 366 2.1E-20 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Gene3D G3DSA:3.90.640.10 246 298 5.6E-19 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Gene3D G3DSA:3.30.1490.110 101 163 5.9E-28 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Gene3D G3DSA:3.30.420.40 195 245 6.9E-5 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 Gene3D G3DSA:3.30.420.40 6 100 5.9E-5 T 28-03-2018 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 SMART SM00842 7 194 2.2E-98 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A21D_RS18375 276549ac5f7ad57e24d339268f4ff960 426 PIRSF PIRSF003101 1 425 4.5E-149 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 Pfam PF00027 Cyclic nucleotide-binding domain 32 113 5.5E-11 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 SUPERFAMILY SSF46785 147 215 8.47E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 Pfam PF13545 Crp-like helix-turn-helix domain 149 214 5.4E-8 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 Gene3D G3DSA:1.10.10.10 142 219 3.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 Gene3D G3DSA:2.60.120.10 2 141 1.9E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS15020 d1726ec51b4b2e5f9453ac8b95a721ee 219 SUPERFAMILY SSF51206 27 143 1.83E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 PRINTS PR00946 Mercury scavenger protein signature 10 26 5.2E-9 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 PRINTS PR00946 Mercury scavenger protein signature 55 68 5.2E-9 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 PRINTS PR00946 Mercury scavenger protein signature 26 41 5.2E-9 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 PRINTS PR00946 Mercury scavenger protein signature 41 55 5.2E-9 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 67 4.3E-18 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 SUPERFAMILY SSF55008 1 67 7.2E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 Gene3D G3DSA:3.30.70.100 1 68 6.5E-24 T 28-03-2018 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 Pfam PF00403 Heavy-metal-associated domain 4 65 4.9E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS02795 99ab1a6576f4913028c1324d86b12ac7 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 Gene3D G3DSA:3.40.50.720 2 113 6.9E-21 T 28-03-2018 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 331 1.8E-28 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 SUPERFAMILY SSF51735 103 301 2.17E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 300 1.8E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 SUPERFAMILY SSF52283 4 134 1.34E-33 T 28-03-2018 A21D_RS13595 3e33a3b2bac833701b6dcabb627f7e24 337 Gene3D G3DSA:3.40.50.720 114 303 2.6E-45 T 28-03-2018 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 Pfam PF14815 NUDIX domain 242 351 7.9E-21 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 Gene3D G3DSA:3.90.79.10 236 362 8.1E-12 T 28-03-2018 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 4.1E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 SMART SM00478 46 197 8.3E-53 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 14 275 1.1E-111 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 SUPERFAMILY SSF48150 11 229 9.58E-77 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 Gene3D G3DSA:1.10.1670.10 125 232 5.4E-37 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 Gene3D G3DSA:1.10.340.30 28 124 1.4E-34 T 28-03-2018 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 SMART SM00525 198 218 0.0011 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 199 215 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A21D_RS11700 1d913b167622ac449d23e3a929491320 362 SUPERFAMILY SSF55811 237 355 5.0E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 Gene3D G3DSA:3.50.50.60 136 244 1.8E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 Gene3D G3DSA:3.50.50.60 252 327 1.3E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 2.9E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 9.1E-18 T 28-03-2018 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.1E-18 T 28-03-2018 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 9.1E-18 T 28-03-2018 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 SUPERFAMILY SSF51905 1 314 2.59E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 Hamap MF_01685 Ferredoxin--NADP reductase. 5 327 44.058 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 2.2E-24 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS13940 7e61adcf084d74fbebee14a4ba41358d 328 Gene3D G3DSA:3.50.50.60 1 135 3.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS17150 327cb3b582b746d9b4c48d972610a8da 73 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 2 62 1.0E-17 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 A21D_RS17150 327cb3b582b746d9b4c48d972610a8da 73 Hamap MF_00363 UPF0154 protein . 2 72 20.762 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 A21D_RS17150 327cb3b582b746d9b4c48d972610a8da 73 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 1.7E-31 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 A21D_RS01595 f6e48397e4901fc76f95a5ea68fda6cd 378 Pfam PF01266 FAD dependent oxidoreductase 5 354 1.5E-53 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS01595 f6e48397e4901fc76f95a5ea68fda6cd 378 SUPERFAMILY SSF54373 226 315 4.19E-14 T 28-03-2018 A21D_RS01595 f6e48397e4901fc76f95a5ea68fda6cd 378 SUPERFAMILY SSF51905 3 223 6.6E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS01595 f6e48397e4901fc76f95a5ea68fda6cd 378 SUPERFAMILY SSF51905 316 372 6.6E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS01595 f6e48397e4901fc76f95a5ea68fda6cd 378 Gene3D G3DSA:3.50.50.60 1 378 1.2E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02655 41b06e693b66abecb4d3cd935dc05451 293 Pfam PF00483 Nucleotidyl transferase 6 258 4.8E-38 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A21D_RS02655 41b06e693b66abecb4d3cd935dc05451 293 SUPERFAMILY SSF53448 5 273 1.06E-72 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS02655 41b06e693b66abecb4d3cd935dc05451 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 1.6E-121 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A21D_RS02655 41b06e693b66abecb4d3cd935dc05451 293 Gene3D G3DSA:3.90.550.10 2 290 1.3E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS19520 87d964a253bb9e68d6a862d042e96f12 191 Pfam PF16729 Domain of unknown function (DUF5067) 44 175 9.9E-29 T 28-03-2018 IPR031989 Domain of unknown function DUF5067 A21D_RS19520 87d964a253bb9e68d6a862d042e96f12 191 Gene3D G3DSA:2.60.40.1240 56 189 1.7E-6 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 119 1.6E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 SUPERFAMILY SSF55347 132 306 1.96E-29 T 28-03-2018 A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 3 337 5.9E-111 T 28-03-2018 IPR030827 Inositol 2-dehydrogenase A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 243 1.4E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 SUPERFAMILY SSF51735 2 154 1.36E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 Gene3D G3DSA:3.40.50.720 1 136 4.6E-35 T 28-03-2018 A21D_RS02005 f60be0cd90f36fdaf4d5c3c6909387b7 341 Gene3D G3DSA:3.30.360.10 137 341 4.5E-41 T 28-03-2018 A21D_RS16410 c49b93701e0090763b45eaa8a22547a4 196 Pfam PF07670 Nucleoside recognition 43 149 3.4E-11 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS16300 e9b901b5bc34b535acd785908e6849d8 211 PIRSF PIRSF038973 1 211 2.0E-55 T 28-03-2018 IPR014196 Stage II sporulation protein M A21D_RS16300 e9b901b5bc34b535acd785908e6849d8 211 Pfam PF01944 Stage II sporulation protein M 23 198 3.5E-22 T 28-03-2018 IPR002798 Stage II sporulation protein M-like A21D_RS16300 e9b901b5bc34b535acd785908e6849d8 211 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 8 204 3.7E-68 T 28-03-2018 IPR014196 Stage II sporulation protein M A21D_RS09470 6c7e9964889a483a59546040aeb49783 224 Gene3D G3DSA:3.20.20.70 6 222 3.2E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS09470 6c7e9964889a483a59546040aeb49783 224 SUPERFAMILY SSF51351 4 218 4.19E-37 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS09470 6c7e9964889a483a59546040aeb49783 224 Pfam PF00121 Triosephosphate isomerase 12 126 1.2E-5 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A21D_RS13030 30c22defcde36c43b8451d71c46b6bb6 69 Pfam PF01381 Helix-turn-helix 5 58 9.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS13030 30c22defcde36c43b8451d71c46b6bb6 69 SUPERFAMILY SSF47413 3 67 2.51E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS13030 30c22defcde36c43b8451d71c46b6bb6 69 Gene3D G3DSA:1.10.260.40 1 69 7.8E-17 T 28-03-2018 A21D_RS13030 30c22defcde36c43b8451d71c46b6bb6 69 SMART SM00530 4 59 5.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 Gene3D G3DSA:1.20.120.220 73 240 5.2E-44 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 19 235 2.2E-47 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 ProSitePatterns PS00449 ATP synthase a subunit signature. 169 178 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 SUPERFAMILY SSF81336 74 233 2.88E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 Pfam PF00119 ATP synthase A chain 25 233 1.5E-57 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 Hamap MF_01393 ATP synthase subunit a [atpB]. 7 239 14.403 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 PRINTS PR00123 ATP synthase A subunit signature 219 234 1.0E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 PRINTS PR00123 ATP synthase A subunit signature 82 98 1.0E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 PRINTS PR00123 ATP synthase A subunit signature 166 188 1.0E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04565 73f26611022c35fdfa8f343e371dfa0e 240 PRINTS PR00123 ATP synthase A subunit signature 150 165 1.0E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 Gene3D G3DSA:3.10.105.10 359 569 5.0E-41 T 28-03-2018 A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 PIRSF PIRSF002741 6 599 3.6E-83 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 Gene3D G3DSA:3.40.190.10 211 358 4.2E-34 T 28-03-2018 A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 Gene3D G3DSA:3.90.76.10 102 210 9.1E-28 T 28-03-2018 A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 118 508 6.9E-85 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS01310 1d9b0ae5607d409c1ced272d458eaeb4 605 SUPERFAMILY SSF53850 63 593 6.15E-112 T 28-03-2018 A21D_RS08875 3ee4e0292dfacb422f77f2189ba5f057 284 Gene3D G3DSA:3.40.50.300 1 276 1.2E-37 T 28-03-2018 A21D_RS08875 3ee4e0292dfacb422f77f2189ba5f057 284 Pfam PF00005 ABC transporter 21 158 5.0E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08875 3ee4e0292dfacb422f77f2189ba5f057 284 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08875 3ee4e0292dfacb422f77f2189ba5f057 284 SMART SM00382 28 207 2.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08875 3ee4e0292dfacb422f77f2189ba5f057 284 SUPERFAMILY SSF52540 17 225 8.04E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 SUPERFAMILY SSF51735 6 249 1.93E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 2.5E-58 T 28-03-2018 A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 Gene3D G3DSA:3.40.50.720 2 48 3.3E-7 T 28-03-2018 A21D_RS01720 45c9f5203df0b50bc5b1ffeb802e735f 251 Gene3D G3DSA:3.40.50.720 49 251 2.4E-61 T 28-03-2018 A21D_RS12885 80adfa176d15591f1fce0f94ad06bebf 525 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 11 499 6.2E-162 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS12885 80adfa176d15591f1fce0f94ad06bebf 525 ProSitePatterns PS01303 BCCT family of transporters signature. 318 327 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS12885 80adfa176d15591f1fce0f94ad06bebf 525 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 48 499 9.7E-147 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS16355 44e84b02dd39aa9ad3ed3f6711f21eba 208 Pfam PF12164 Stage V sporulation protein AA 3 88 4.5E-16 T 28-03-2018 IPR021997 Stage V sporulation protein AA A21D_RS16355 44e84b02dd39aa9ad3ed3f6711f21eba 208 Gene3D G3DSA:2.60.480.10 2 92 6.0E-21 T 28-03-2018 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 Gene3D G3DSA:3.40.605.10 2 267 2.5E-101 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 Pfam PF00171 Aldehyde dehydrogenase family 18 482 1.3E-175 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 Gene3D G3DSA:3.40.309.10 268 466 2.8E-70 T 28-03-2018 A21D_RS11490 c937545ee4c71867be49b9eb07e3f965 498 SUPERFAMILY SSF53720 7 486 6.28E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 SUPERFAMILY SSF64397 2 241 1.31E-75 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 39.908 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 Pfam PF01430 Hsp33 protein 3 279 1.5E-90 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 Gene3D G3DSA:3.55.30.10 2 234 1.1E-73 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 SUPERFAMILY SSF118352 232 289 2.88E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 Gene3D G3DSA:3.90.1280.10 235 287 2.8E-23 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A21D_RS06650 56db1b59d40d32cece774944c429e224 294 PIRSF PIRSF005261 2 291 2.7E-75 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A21D_RS13670 92b35f847b29298f377091fea0fc1610 77 Gene3D G3DSA:1.10.260.40 1 63 3.8E-13 T 28-03-2018 A21D_RS13670 92b35f847b29298f377091fea0fc1610 77 Pfam PF01381 Helix-turn-helix 6 59 6.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS13670 92b35f847b29298f377091fea0fc1610 77 SMART SM00530 5 60 9.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS13670 92b35f847b29298f377091fea0fc1610 77 SUPERFAMILY SSF47413 3 64 2.29E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 Gene3D G3DSA:1.20.1250.20 267 491 7.3E-23 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 Gene3D G3DSA:1.20.1250.20 17 208 1.3E-24 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 310 334 1.8E-9 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 1.8E-9 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 1.8E-9 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 1.8E-9 T 28-03-2018 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 SUPERFAMILY SSF103473 256 477 1.11E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03595 816823d477873260a9a24f383537c5f3 499 SUPERFAMILY SSF103473 18 205 1.11E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS03595 816823d477873260a9a24f383537c5f3 499 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 441 1.1E-102 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A21D_RS03595 816823d477873260a9a24f383537c5f3 499 Pfam PF07690 Major Facilitator Superfamily 26 417 1.8E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 SMART SM00382 35 243 4.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 8.9E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 Pfam PF00005 ABC transporter 27 185 4.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 4.1E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 SUPERFAMILY SSF52540 35 315 2.08E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03560 05d023f0f5b9e12740cd85225ba63417 326 Gene3D G3DSA:3.40.50.300 3 326 1.7E-82 T 28-03-2018 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 Gene3D G3DSA:3.30.70.60 1 96 2.1E-31 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 SUPERFAMILY SSF54995 1 95 1.28E-34 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.922 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.6E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS07325 736d98f3c3199328d209efd2e0c62fb6 96 Pfam PF01250 Ribosomal protein S6 3 92 1.3E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS01845 16f9fb4bd22ad516d4dd3485472665ac 505 Gene3D G3DSA:3.40.605.10 13 281 7.8E-103 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01845 16f9fb4bd22ad516d4dd3485472665ac 505 Gene3D G3DSA:3.40.309.10 282 477 2.1E-76 T 28-03-2018 A21D_RS01845 16f9fb4bd22ad516d4dd3485472665ac 505 SUPERFAMILY SSF53720 14 492 1.44E-173 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS01845 16f9fb4bd22ad516d4dd3485472665ac 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS01845 16f9fb4bd22ad516d4dd3485472665ac 505 Pfam PF00171 Aldehyde dehydrogenase family 31 491 4.0E-180 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS00110 b26152708626887e8b4caaaf5a74807d 202 Pfam PF13392 HNH endonuclease 121 163 8.0E-10 T 28-03-2018 IPR003615 HNH nuclease A21D_RS00110 b26152708626887e8b4caaaf5a74807d 202 SUPERFAMILY SSF54060 94 163 4.0E-7 T 28-03-2018 A21D_RS13450 5e9d51cdf2482475e92ab40ddbf8fbf8 400 SUPERFAMILY SSF51445 127 253 1.14E-7 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS13450 5e9d51cdf2482475e92ab40ddbf8fbf8 400 Pfam PF13200 Putative glycosyl hydrolase domain 67 388 8.9E-127 T 28-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 A21D_RS13450 5e9d51cdf2482475e92ab40ddbf8fbf8 400 Gene3D G3DSA:3.20.20.70 68 265 6.7E-11 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 46.591 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 Gene3D G3DSA:3.20.20.60 10 298 3.0E-84 T 28-03-2018 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 258 1.0E-50 T 28-03-2018 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 5.3E-127 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A21D_RS11235 e6ac9886337fd798c65c78ea9799de50 300 SUPERFAMILY SSF51621 10 294 3.14E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 Gene3D G3DSA:3.40.710.10 315 690 2.9E-74 T 28-03-2018 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 Pfam PF00905 Penicillin binding protein transpeptidase domain 349 681 4.6E-63 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 298 1.6E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 Gene3D G3DSA:3.90.1310.10 30 314 2.2E-34 T 28-03-2018 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 SUPERFAMILY SSF56601 315 685 6.22E-65 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 SUPERFAMILY SSF56519 58 119 8.89E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS01620 d14ce9bdf41e05eaf80972db7d71ef1c 690 SUPERFAMILY SSF56519 183 314 8.89E-36 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A21D_RS13170 f6bc8e04e3b7b9636ec70916c515ecf2 144 Pfam PF00210 Ferritin-like domain 9 140 4.4E-25 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A21D_RS13170 f6bc8e04e3b7b9636ec70916c515ecf2 144 SUPERFAMILY SSF47240 7 140 2.13E-30 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS13170 f6bc8e04e3b7b9636ec70916c515ecf2 144 Gene3D G3DSA:1.20.1260.10 1 140 3.1E-25 T 28-03-2018 IPR012347 Ferritin-related A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 Pfam PF09383 NIL domain 265 337 5.0E-19 T 28-03-2018 IPR018449 NIL domain A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 Pfam PF00005 ABC transporter 22 169 1.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 SMART SM00382 30 218 2.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 Gene3D G3DSA:3.40.50.300 1 257 6.1E-77 T 28-03-2018 A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 SUPERFAMILY SSF52540 1 240 1.56E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 SMART SM00930 263 339 1.2E-25 T 28-03-2018 IPR018449 NIL domain A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 Gene3D G3DSA:3.30.70.260 258 341 1.0E-21 T 28-03-2018 A21D_RS00255 8a468d38a219becc7e54cc92d7b5b96d 343 SUPERFAMILY SSF55021 251 340 5.15E-19 T 28-03-2018 A21D_RS19230 21f55d7f70b57503f3923b9cce30b256 85 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 7 71 1.0E-17 T 28-03-2018 A21D_RS19230 21f55d7f70b57503f3923b9cce30b256 85 Pfam PF11132 Transcriptional regulator protein (SplA) 5 75 5.0E-29 T 28-03-2018 IPR022608 Transcription regulator SplA A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 Gene3D G3DSA:3.40.50.880 1 192 3.8E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 Pfam PF00117 Glutamine amidotransferase class-I 3 187 4.3E-53 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 8.2E-67 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 SUPERFAMILY SSF52317 1 190 3.93E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.3E-13 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.2E-32 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.1E-10 T 28-03-2018 A21D_RS03225 bb3c3e4522406d81e39c97f2fcc2d138 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.1E-10 T 28-03-2018 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 3.6E-52 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 PIRSF PIRSF005419 1 677 7.9E-257 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 674 2.2E-269 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 Pfam PF00771 FHIPEP family 15 666 4.7E-271 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A21D_RS17850 cb8144289621d678e547ee24a20c10ba 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 28-03-2018 IPR025505 FHIPEP conserved site A21D_RS01770 7f0e30a596cc5282909e2f4af56925ed 325 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 146 320 4.2E-11 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A21D_RS01935 1c50841538afa95554b4f3d9560ed40c 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 61 186 2.4E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS01935 1c50841538afa95554b4f3d9560ed40c 221 Gene3D G3DSA:1.10.150.240 29 85 1.1E-9 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A21D_RS01935 1c50841538afa95554b4f3d9560ed40c 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 193 4.7E-42 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01935 1c50841538afa95554b4f3d9560ed40c 221 Gene3D G3DSA:3.40.50.1000 86 220 6.3E-29 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01935 1c50841538afa95554b4f3d9560ed40c 221 SUPERFAMILY SSF56784 9 218 7.2E-51 T 28-03-2018 IPR023214 HAD-like domain A21D_RS01745 9bbcc26253838f327e375dd168ecfedc 238 TIGRFAM TIGR01076 sortase_fam: sortase 100 230 2.0E-42 T 28-03-2018 IPR005754 Sortase family A21D_RS01745 9bbcc26253838f327e375dd168ecfedc 238 Pfam PF04203 Sortase family 101 226 2.0E-25 T 28-03-2018 IPR005754 Sortase family A21D_RS01745 9bbcc26253838f327e375dd168ecfedc 238 SUPERFAMILY SSF63817 92 227 1.57E-37 T 28-03-2018 IPR023365 Sortase domain A21D_RS01745 9bbcc26253838f327e375dd168ecfedc 238 Gene3D G3DSA:2.40.260.10 31 238 5.8E-46 T 28-03-2018 IPR023365 Sortase domain A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 SMART SM01210 325 412 9.5E-21 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 412 9.7E-148 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 SUPERFAMILY SSF51246 324 412 1.02E-19 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 3.2E-75 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 SMART SM01209 101 293 4.3E-116 T 28-03-2018 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 413 37.949 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.0E-31 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 413 2.3E-19 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 SUPERFAMILY SSF52440 1 101 1.87E-31 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 SUPERFAMILY SSF56059 102 321 2.65E-58 T 28-03-2018 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Gene3D G3DSA:3.30.1490.20 85 187 2.1E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Gene3D G3DSA:3.40.50.20 2 84 1.8E-33 T 28-03-2018 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Gene3D G3DSA:3.30.470.20 189 325 9.4E-53 T 28-03-2018 A21D_RS10975 8da72db1039f0b5da1d4fd09625e2711 413 Gene3D G3DSA:3.90.600.10 326 413 4.3E-21 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 1.3E-58 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 SUPERFAMILY SSF75217 1 157 2.15E-58 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 Gene3D G3DSA:3.40.1280.10 1 159 5.1E-61 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 2.4E-60 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.481 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS07595 4307c0c39d31d7012a11674b206bb44c 159 PIRSF PIRSF004505 1 159 2.7E-52 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS18490 04f4417c91deb2faf630e4d11c383a7b 91 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 6.6E-28 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 A21D_RS18490 04f4417c91deb2faf630e4d11c383a7b 91 PIRSF PIRSF031653 1 91 2.1E-32 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 A21D_RS18490 04f4417c91deb2faf630e4d11c383a7b 91 Hamap MF_01126 UPF0298 protein . 1 78 21.863 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 A21D_RS17410 b61f07cc56ab6e7680680ec3ea2c8ccb 98 SMART SM00990 4 86 3.5E-5 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 A21D_RS17410 b61f07cc56ab6e7680680ec3ea2c8ccb 98 Gene3D G3DSA:3.40.1350.10 7 97 9.2E-5 T 28-03-2018 A21D_RS17410 b61f07cc56ab6e7680680ec3ea2c8ccb 98 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 87 3.2E-5 T 28-03-2018 IPR002732 Holliday junction resolvase Hjc A21D_RS17410 b61f07cc56ab6e7680680ec3ea2c8ccb 98 SUPERFAMILY SSF52980 8 80 6.26E-12 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS01710 64eacdadfd40fc41e4ca7b7f1802cf3c 352 SUPERFAMILY SSF58100 41 350 1.28E-59 T 28-03-2018 A21D_RS01710 64eacdadfd40fc41e4ca7b7f1802cf3c 352 Gene3D G3DSA:1.20.1170.10 34 352 7.2E-36 T 28-03-2018 A21D_RS01710 64eacdadfd40fc41e4ca7b7f1802cf3c 352 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 43 216 8.6E-30 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 A21D_RS08330 2a3a70f2f032ee448d95a35ba0cdedbe 234 Pfam PF02146 Sir2 family 17 187 2.4E-49 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 A21D_RS08330 2a3a70f2f032ee448d95a35ba0cdedbe 234 SUPERFAMILY SSF52467 2 232 5.14E-79 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS08330 2a3a70f2f032ee448d95a35ba0cdedbe 234 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 1 233 60.885 T 28-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 A21D_RS08330 2a3a70f2f032ee448d95a35ba0cdedbe 234 Gene3D G3DSA:3.40.50.1220 1 233 8.9E-65 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A21D_RS00530 4317fef984fe477ac50fdc9cc0da1fb8 343 SUPERFAMILY SSF46785 19 84 8.44E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00530 4317fef984fe477ac50fdc9cc0da1fb8 343 Gene3D G3DSA:3.40.50.1360 88 338 1.4E-37 T 28-03-2018 A21D_RS00530 4317fef984fe477ac50fdc9cc0da1fb8 343 SUPERFAMILY SSF100950 90 337 2.93E-67 T 28-03-2018 A21D_RS00530 4317fef984fe477ac50fdc9cc0da1fb8 343 Gene3D G3DSA:1.10.10.10 17 87 5.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00530 4317fef984fe477ac50fdc9cc0da1fb8 343 Pfam PF04198 Putative sugar-binding domain 91 338 1.1E-69 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 3.1E-7 T 28-03-2018 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 3.1E-7 T 28-03-2018 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 3.1E-7 T 28-03-2018 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 SUPERFAMILY SSF103473 3 191 2.35E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 SUPERFAMILY SSF103473 242 440 2.35E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 Pfam PF07690 Major Facilitator Superfamily 16 403 9.5E-59 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 Gene3D G3DSA:1.20.1250.20 250 450 5.4E-28 T 28-03-2018 A21D_RS19410 243bedf5a6b470c5c149c53221024f0c 451 Gene3D G3DSA:1.20.1250.20 1 198 1.5E-31 T 28-03-2018 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 214 8.4E-65 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 SUPERFAMILY SSF109755 4 217 1.67E-62 T 28-03-2018 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 PIRSF PIRSF003107 1 218 1.8E-64 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 Gene3D G3DSA:1.20.58.220 113 218 1.2E-22 T 28-03-2018 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 Gene3D G3DSA:1.20.58.220 1 112 1.1E-26 T 28-03-2018 A21D_RS15865 33878426671ff63640a4d0acc50db477 218 Pfam PF01895 PhoU domain 121 205 1.1E-16 T 28-03-2018 IPR026022 PhoU domain A21D_RS15865 33878426671ff63640a4d0acc50db477 218 Pfam PF01895 PhoU domain 19 106 6.1E-23 T 28-03-2018 IPR026022 PhoU domain A21D_RS19155 833bfe20ad220c6edeeddda993487c4a 514 Pfam PF15975 Flotillin 368 462 7.8E-13 T 28-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 A21D_RS19155 833bfe20ad220c6edeeddda993487c4a 514 SMART SM00244 119 301 5.9E-5 T 28-03-2018 IPR001107 Band 7 domain A21D_RS19155 833bfe20ad220c6edeeddda993487c4a 514 SUPERFAMILY SSF117892 68 210 4.05E-34 T 28-03-2018 IPR001107 Band 7 domain A21D_RS19155 833bfe20ad220c6edeeddda993487c4a 514 Pfam PF01145 SPFH domain / Band 7 family 30 219 2.0E-24 T 28-03-2018 IPR001107 Band 7 domain A21D_RS05245 82e09148ecfb6e22dcab303b2b81a5f2 470 Pfam PF03611 PTS system sugar-specific permease component 15 393 1.1E-47 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS05245 82e09148ecfb6e22dcab303b2b81a5f2 470 PIRSF PIRSF006304 8 468 1.6E-145 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Pfam PF06725 3D domain 357 418 1.0E-19 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 SMART SM01208 210 288 6.5E-28 T 28-03-2018 IPR011098 G5 domain A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Gene3D G3DSA:2.40.40.10 205 417 1.1E-40 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Pfam PF03990 Domain of unknown function (DUF348) 46 81 2.4E-11 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Pfam PF03990 Domain of unknown function (DUF348) 100 134 1.1E-5 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Pfam PF03990 Domain of unknown function (DUF348) 155 197 5.2E-7 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 Pfam PF07501 G5 domain 214 287 2.2E-20 T 28-03-2018 IPR011098 G5 domain A21D_RS06805 a091f319a7bff50d8c08e863141122b2 418 SUPERFAMILY SSF50685 358 404 3.17E-6 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS10185 b6a4364801faaa150d45641d3265d56c 151 Gene3D G3DSA:3.40.630.30 1 151 1.4E-32 T 28-03-2018 A21D_RS10185 b6a4364801faaa150d45641d3265d56c 151 Pfam PF00583 Acetyltransferase (GNAT) family 26 124 5.4E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS10185 b6a4364801faaa150d45641d3265d56c 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 3.5E-40 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A21D_RS10185 b6a4364801faaa150d45641d3265d56c 151 SUPERFAMILY SSF55729 5 149 7.6E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 Gene3D G3DSA:3.10.410.10 444 532 2.1E-37 T 28-03-2018 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 Gene3D G3DSA:3.40.50.300 12 234 4.5E-95 T 28-03-2018 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 Gene3D G3DSA:3.40.50.300 235 442 4.0E-73 T 28-03-2018 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 Pfam PF01268 Formate--tetrahydrofolate ligase 3 556 3.8E-268 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 SUPERFAMILY SSF52540 4 554 5.05E-243 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A21D_RS16840 e92aed749c93ce1f14fd3296c4c14573 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 47.926 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 5.3E-75 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 SUPERFAMILY SSF52166 1 206 1.44E-83 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 Gene3D G3DSA:3.40.1370.10 2 146 2.1E-61 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 Gene3D G3DSA:3.40.1370.10 147 204 9.8E-13 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 202 5.4E-84 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06370 3e2d49dd77fd9764e9ca17be53f4ab0d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 37.436 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 SUPERFAMILY SSF52172 5 191 2.2E-45 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 SMART SM00448 5 115 4.0E-48 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 1.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 SMART SM00862 156 233 1.1E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 Pfam PF00072 Response regulator receiver domain 7 115 1.9E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 Gene3D G3DSA:3.40.50.2300 1 129 1.9E-41 T 28-03-2018 A21D_RS16440 48180fd4af1b149302845278b7e565d4 238 Gene3D G3DSA:1.10.10.10 130 238 4.3E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 SUPERFAMILY SSF55804 499 637 4.36E-21 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Gene3D G3DSA:3.40.50.2300 396 487 6.6E-7 T 28-03-2018 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Gene3D G3DSA:1.10.10.10 1 66 5.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 499 636 4.5E-19 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 SUPERFAMILY SSF63520 291 392 9.94E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Pfam PF00874 PRD domain 306 389 7.2E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Pfam PF08279 HTH domain 5 62 5.1E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 SUPERFAMILY SSF46785 2 64 2.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Gene3D G3DSA:3.40.930.10 496 639 2.4E-22 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Gene3D G3DSA:1.10.1790.10 277 395 1.7E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Gene3D G3DSA:1.10.10.10 88 154 1.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08020 75ea9d8681da7b74b7586b2b5b06492a 651 Pfam PF05043 Mga helix-turn-helix domain 91 164 1.5E-5 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS01245 b82dca182eb844711d88b1914156b889 537 Pfam PF01019 Gamma-glutamyltranspeptidase 38 532 2.3E-157 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 435 452 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 132 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 45 70 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 236 252 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 411 426 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 265 284 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 356 374 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 398 2.6E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A21D_RS01245 b82dca182eb844711d88b1914156b889 537 SUPERFAMILY SSF56235 7 537 5.6E-178 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS16100 28dc651afd0a3fd53f5379e0e1deb1aa 132 Pfam PF03780 Asp23 family, cell envelope-related function 14 119 2.8E-36 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 SUPERFAMILY SSF82549 1 279 3.66E-94 T 28-03-2018 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 Gene3D G3DSA:3.40.50.10440 54 150 1.1E-34 T 28-03-2018 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 1.4E-105 T 28-03-2018 IPR003797 DegV A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 Gene3D G3DSA:3.30.1180.10 151 281 6.9E-39 T 28-03-2018 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 Gene3D G3DSA:2.20.28.50 35 53 8.3E-14 T 28-03-2018 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 Gene3D G3DSA:3.40.50.10440 1 34 2.4E-4 T 28-03-2018 A21D_RS00910 854d992c301410917dfecc2e19d60b33 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 2.9E-98 T 28-03-2018 IPR003797 DegV A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 SMART SM00283 192 434 5.9E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 Pfam PF11563 Protoglobin 31 181 1.7E-41 T 28-03-2018 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 Gene3D G3DSA:1.10.490.10 16 184 5.7E-34 T 28-03-2018 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 SUPERFAMILY SSF58104 198 431 2.22E-53 T 28-03-2018 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 SUPERFAMILY SSF58104 150 160 2.22E-53 T 28-03-2018 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 SUPERFAMILY SSF46458 13 175 3.8E-38 T 28-03-2018 IPR009050 Globin-like A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 238 423 8.8E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS11385 949aedcbe8aa905ed683b351f10082c1 434 Gene3D G3DSA:1.10.287.950 217 434 4.1E-46 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Gene3D G3DSA:3.50.50.60 251 338 1.4E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 SUPERFAMILY SSF51905 1 314 3.4E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 428 9.5E-14 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 2.6E-17 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.6E-17 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.6E-17 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.6E-17 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 SUPERFAMILY SSF52821 430 541 1.57E-29 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 SMART SM00450 453 547 9.7E-22 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 SUPERFAMILY SSF55424 322 446 2.58E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Pfam PF00581 Rhodanese-like domain 458 539 8.7E-15 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Gene3D G3DSA:3.50.50.60 1 127 3.4E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 305 3.1E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Gene3D G3DSA:3.30.390.30 339 444 1.7E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.0E-23 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.0E-23 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.0E-23 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.0E-23 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-23 T 28-03-2018 A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Gene3D G3DSA:3.40.250.10 445 555 7.4E-26 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS18995 e09e88b16a6f2fbd161650ef3cbce7e4 564 Gene3D G3DSA:3.50.50.60 128 250 2.5E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07100 e89ff9aeb1184ba100ca135673884715 215 Pfam PF13599 Pentapeptide repeats (9 copies) 110 176 4.6E-13 T 28-03-2018 IPR001646 Pentapeptide repeat A21D_RS07100 e89ff9aeb1184ba100ca135673884715 215 SUPERFAMILY SSF141571 45 213 3.83E-42 T 28-03-2018 A21D_RS07100 e89ff9aeb1184ba100ca135673884715 215 Gene3D G3DSA:2.160.20.80 117 209 3.0E-15 T 28-03-2018 A21D_RS07100 e89ff9aeb1184ba100ca135673884715 215 Pfam PF00805 Pentapeptide repeats (8 copies) 51 87 7.6E-8 T 28-03-2018 IPR001646 Pentapeptide repeat A21D_RS07100 e89ff9aeb1184ba100ca135673884715 215 Gene3D G3DSA:2.160.10.20 28 116 7.1E-18 T 28-03-2018 A21D_RS13905 1026032789e66b7adbd7e089c136d376 170 Gene3D G3DSA:1.10.3760.10 1 167 1.9E-62 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A21D_RS13905 1026032789e66b7adbd7e089c136d376 170 SUPERFAMILY SSF101307 11 161 1.96E-55 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A21D_RS13905 1026032789e66b7adbd7e089c136d376 170 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 1.1E-19 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A21D_RS13905 1026032789e66b7adbd7e089c136d376 170 PIRSF PIRSF019587 5 166 1.4E-78 T 28-03-2018 IPR026038 Putative phosphatidylglycerophosphatase A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 SUPERFAMILY SSF55144 5 185 1.92E-35 T 28-03-2018 IPR009097 Cyclic phosphodiesterase A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 Gene3D G3DSA:3.90.1140.10 2 185 9.0E-28 T 28-03-2018 A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 185 3.6E-42 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 Pfam PF02834 LigT like Phosphoesterase 24 93 2.3E-13 T 28-03-2018 IPR014051 Phosphoesterase, HXTX A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 Pfam PF02834 LigT like Phosphoesterase 98 176 4.0E-7 T 28-03-2018 IPR014051 Phosphoesterase, HXTX A21D_RS14245 4273542b8b647df1d94ac9ddd535abba 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 185 18.561 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A21D_RS01645 165954c5a8805d6283544603f962a962 229 Gene3D G3DSA:3.20.20.380 1 226 3.9E-71 T 28-03-2018 A21D_RS01645 165954c5a8805d6283544603f962a962 229 SUPERFAMILY SSF110395 1 217 1.7E-57 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A21D_RS01645 165954c5a8805d6283544603f962a962 229 Pfam PF03932 CutC family 1 204 3.4E-56 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A21D_RS15675 f34c92c6b65bb7f66aa4bdcefbfcfc43 149 Gene3D G3DSA:1.10.1510.10 1 91 2.9E-27 T 28-03-2018 A21D_RS15675 f34c92c6b65bb7f66aa4bdcefbfcfc43 149 SUPERFAMILY SSF89095 2 148 1.15E-42 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A21D_RS15675 f34c92c6b65bb7f66aa4bdcefbfcfc43 149 Pfam PF09424 Yqey-like protein 5 147 1.6E-53 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial A21D_RS15675 f34c92c6b65bb7f66aa4bdcefbfcfc43 149 Gene3D G3DSA:1.10.10.410 92 148 1.6E-20 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A21D_RS04420 d32d9b22d581ef910b5698a6f96550d6 284 Gene3D G3DSA:2.40.50.100 54 114 2.0E-14 T 28-03-2018 A21D_RS04420 d32d9b22d581ef910b5698a6f96550d6 284 SUPERFAMILY SSF51230 61 129 5.02E-10 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS04420 d32d9b22d581ef910b5698a6f96550d6 284 Pfam PF13437 HlyD family secretion protein 101 197 2.8E-14 T 28-03-2018 A21D_RS04420 d32d9b22d581ef910b5698a6f96550d6 284 Gene3D G3DSA:2.40.50.100 115 280 0.0017 T 28-03-2018 A21D_RS04420 d32d9b22d581ef910b5698a6f96550d6 284 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 99 280 6.6E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A21D_RS11465 ce461d023dfe174a68e4b9d5ec5ac693 217 Gene3D G3DSA:3.50.30.50 1 212 3.6E-55 T 28-03-2018 A21D_RS11465 ce461d023dfe174a68e4b9d5ec5ac693 217 TIGRFAM TIGR03035 trp_arylform: arylformamidase 3 208 4.2E-77 T 28-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A21D_RS11465 ce461d023dfe174a68e4b9d5ec5ac693 217 Pfam PF04199 Putative cyclase 5 151 9.0E-25 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A21D_RS11465 ce461d023dfe174a68e4b9d5ec5ac693 217 Hamap MF_01969 Kynurenine formamidase [kynB]. 3 208 39.279 T 28-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A21D_RS11465 ce461d023dfe174a68e4b9d5ec5ac693 217 SUPERFAMILY SSF102198 2 205 1.02E-58 T 28-03-2018 A21D_RS01195 081b6bc0b7b831dc92c0e98f1002bde5 323 Gene3D G3DSA:3.30.420.10 148 318 2.4E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS01195 081b6bc0b7b831dc92c0e98f1002bde5 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS01195 081b6bc0b7b831dc92c0e98f1002bde5 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS01195 081b6bc0b7b831dc92c0e98f1002bde5 323 SUPERFAMILY SSF53098 160 309 1.02E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12985 41999c099c611022002baf64a49e9be9 431 Pfam PF11700 Vacuole effluxer Atg22 like 44 417 3.8E-71 T 28-03-2018 IPR024671 Autophagy-related protein 22-like A21D_RS12985 41999c099c611022002baf64a49e9be9 431 Gene3D G3DSA:1.20.1250.20 3 213 1.0E-11 T 28-03-2018 A21D_RS12985 41999c099c611022002baf64a49e9be9 431 Gene3D G3DSA:1.20.1250.20 219 413 4.9E-21 T 28-03-2018 A21D_RS12985 41999c099c611022002baf64a49e9be9 431 SUPERFAMILY SSF103473 4 413 2.22E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS09300 03cc676b9d990f02902e80eba8892402 125 Gene3D G3DSA:1.10.1790.10 3 119 1.2E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09300 03cc676b9d990f02902e80eba8892402 125 SUPERFAMILY SSF63520 45 117 1.02E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09300 03cc676b9d990f02902e80eba8892402 125 Pfam PF00874 PRD domain 42 113 7.2E-10 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS18130 594abdaf0529d9a06c0deb951c47f781 291 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 1.4E-134 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS18130 594abdaf0529d9a06c0deb951c47f781 291 Gene3D G3DSA:1.10.4100.10 88 257 4.1E-25 T 28-03-2018 A21D_RS18130 594abdaf0529d9a06c0deb951c47f781 291 Pfam PF03313 Serine dehydratase alpha chain 16 274 7.1E-71 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A21D_RS11105 64a61a9a427564e79b29a3f92ad62b66 82 Gene3D G3DSA:1.10.260.40 6 82 3.8E-13 T 28-03-2018 A21D_RS11105 64a61a9a427564e79b29a3f92ad62b66 82 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 2.5E-24 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS11105 64a61a9a427564e79b29a3f92ad62b66 82 SUPERFAMILY SSF47413 1 68 7.88E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS11105 64a61a9a427564e79b29a3f92ad62b66 82 SMART SM00530 6 62 1.0E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 Pfam PF00248 Aldo/keto reductase family 15 279 5.4E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 SUPERFAMILY SSF51430 1 297 5.37E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 Gene3D G3DSA:3.20.20.100 1 303 3.0E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 PRINTS PR00069 Aldo-keto reductase signature 37 61 9.7E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 PRINTS PR00069 Aldo-keto reductase signature 103 121 9.7E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS16285 6146b3362006b0c2fbed556923fe3ec0 305 PRINTS PR00069 Aldo-keto reductase signature 134 151 9.7E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS02315 e5270b72ea21a93ec09311aad6ec87c4 184 PIRSF PIRSF016661 1 176 1.1E-41 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS02315 e5270b72ea21a93ec09311aad6ec87c4 184 Pfam PF02632 BioY family 29 172 1.1E-33 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 PIRSF PIRSF016184 2 301 7.3E-87 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 Gene3D G3DSA:3.10.310.10 1 136 4.6E-32 T 28-03-2018 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 Gene3D G3DSA:3.10.310.10 137 290 2.2E-36 T 28-03-2018 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 SUPERFAMILY SSF54506 4 300 2.3E-69 T 28-03-2018 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 299 4.1E-95 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS11995 5ed1357be01c36eabf1abab9b8769214 301 Pfam PF02567 Phenazine biosynthesis-like protein 10 296 3.4E-76 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A21D_RS18385 bec462fe5eb805c7029bd79e48a2d3ff 354 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 3 350 1.5E-170 T 28-03-2018 IPR013438 Sporulation stage V, protein E A21D_RS18385 bec462fe5eb805c7029bd79e48a2d3ff 354 Pfam PF01098 Cell cycle protein 4 353 1.8E-123 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A21D_RS18385 bec462fe5eb805c7029bd79e48a2d3ff 354 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 310 334 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A21D_RS18385 bec462fe5eb805c7029bd79e48a2d3ff 354 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 2 351 1.7E-128 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 129 140 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 3.1E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 1.4E-84 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 SUPERFAMILY SSF51569 4 284 2.05E-93 T 28-03-2018 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 PIRSF PIRSF001359 1 284 1.1E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS07895 227f49f01c6ea69c61c2fcfa2f7657d3 289 Gene3D G3DSA:3.20.20.70 2 289 1.2E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 SUPERFAMILY SSF51905 98 260 2.53E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 SUPERFAMILY SSF51905 7 67 2.53E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 SMART SM01228 545 616 1.3E-42 T 28-03-2018 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 Gene3D G3DSA:3.50.50.60 6 265 2.4E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 1.0E-284 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 Pfam PF13932 GidA associated domain 401 614 2.7E-78 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.4E-6 T 28-03-2018 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.4E-6 T 28-03-2018 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 Pfam PF01134 Glucose inhibited division protein A 9 397 1.4E-166 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 41.929 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A21D_RS07260 88f25f81e49cd5f107f1c9b87ad7f233 628 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 SUPERFAMILY SSF110849 25 116 5.75E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 SUPERFAMILY SSF109709 106 216 9.15E-36 T 28-03-2018 A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 Gene3D G3DSA:3.90.1530.10 13 114 1.3E-35 T 28-03-2018 A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 23 198 9.1E-66 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 SMART SM00470 25 114 8.2E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 Gene3D G3DSA:1.10.10.730 115 162 1.4E-18 T 28-03-2018 A21D_RS07280 6994ecc738221f7c903697245ba7a118 279 Pfam PF02195 ParB-like nuclease domain 25 113 1.7E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 SUPERFAMILY SSF51316 181 320 1.36E-60 T 28-03-2018 IPR011057 Mss4-like A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Pfam PF01641 SelR domain 185 305 1.9E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 10 160 1.5E-59 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Gene3D G3DSA:2.170.150.20 175 322 3.5E-56 T 28-03-2018 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Pfam PF01625 Peptide methionine sulfoxide reductase 11 160 1.2E-59 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 8 167 35.352 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Gene3D G3DSA:3.30.1060.10 1 174 1.1E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 173 306 38.67 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 SUPERFAMILY SSF55068 8 172 3.14E-69 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS16905 f8d69ea75196d3fe3a10724c9b03ed86 323 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 182 314 8.1E-64 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A21D_RS10255 a81f71a58c1c86e90bb09efec4018215 133 Pfam PF12844 Helix-turn-helix domain 16 75 1.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS10255 a81f71a58c1c86e90bb09efec4018215 133 SUPERFAMILY SSF47413 9 78 1.01E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS10255 a81f71a58c1c86e90bb09efec4018215 133 Gene3D G3DSA:1.10.260.40 8 133 6.3E-22 T 28-03-2018 A21D_RS10255 a81f71a58c1c86e90bb09efec4018215 133 SMART SM00530 18 74 3.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS00540 2acbdb2c6cb8d5a6f65a4875cdbd1c18 84 Gene3D G3DSA:3.40.30.10 2 84 3.3E-7 T 28-03-2018 A21D_RS00540 2acbdb2c6cb8d5a6f65a4875cdbd1c18 84 SUPERFAMILY SSF52833 3 80 1.92E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS00540 2acbdb2c6cb8d5a6f65a4875cdbd1c18 84 Pfam PF05768 Glutaredoxin-like domain (DUF836) 4 76 1.8E-11 T 28-03-2018 IPR008554 Glutaredoxin-like A21D_RS06080 99ea31e5f2bddb2c0c25d0ae46ef3151 114 SUPERFAMILY SSF159121 28 112 1.31E-24 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 A21D_RS06080 99ea31e5f2bddb2c0c25d0ae46ef3151 114 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 111 1.7E-23 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 A21D_RS06080 99ea31e5f2bddb2c0c25d0ae46ef3151 114 Pfam PF06486 Protein of unknown function (DUF1093) 32 99 3.6E-20 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 A21D_RS16280 4a5d18d1c9dcd0d6643e67108e04e57d 109 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 97 2.2E-12 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS16280 4a5d18d1c9dcd0d6643e67108e04e57d 109 SUPERFAMILY SSF89360 1 97 3.92E-15 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS16280 4a5d18d1c9dcd0d6643e67108e04e57d 109 Gene3D G3DSA:2.60.300.12 1 105 2.3E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 SMART SM00382 136 295 0.0023 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 Pfam PF00437 Type II/IV secretion system protein 11 273 3.3E-61 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 Gene3D G3DSA:3.30.450.90 2 109 6.3E-27 T 28-03-2018 A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 Gene3D G3DSA:3.40.50.300 110 314 1.1E-18 T 28-03-2018 A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 SUPERFAMILY SSF52540 9 298 1.53E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15980 0b75805e528c62884baf5a2e9e9c7bd5 337 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 3 285 4.6E-123 T 28-03-2018 IPR014215 Dipicolinic acid synthetase subunit A A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 SUPERFAMILY SSF51735 132 247 2.9E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 Gene3D G3DSA:3.40.50.720 1 136 2.2E-4 T 28-03-2018 A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 281 3.0E-8 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 4 121 1.2E-26 T 28-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal A21D_RS17680 298242a2db94fba2c7cd1280dbc310bf 292 Gene3D G3DSA:3.40.50.720 137 282 5.3E-19 T 28-03-2018 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 Gene3D G3DSA:3.50.50.60 170 332 1.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 306 1.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 Gene3D G3DSA:3.50.50.60 1 169 3.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 332 35.649 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 3.6E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 3.6E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.6E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 3.6E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 8.1E-16 T 28-03-2018 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 8.1E-16 T 28-03-2018 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 8.1E-16 T 28-03-2018 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 8.1E-16 T 28-03-2018 A21D_RS05795 83137e7e3f9f8bd0a37d1f76078ca13f 349 SUPERFAMILY SSF51905 7 315 5.5E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07410 5d5a8d34696f3476241c698f232dcd6d 124 Pfam PF07681 DoxX 16 87 6.2E-9 T 28-03-2018 IPR032808 DoxX family A21D_RS18395 e92cf30eefb9931861305133b894fc40 328 ProSitePatterns PS01348 MraY family signature 2. 170 181 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS18395 e92cf30eefb9931861305133b894fc40 328 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 325 24.8 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS18395 e92cf30eefb9931861305133b894fc40 328 Pfam PF00953 Glycosyl transferase family 4 83 251 2.6E-38 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A21D_RS18395 e92cf30eefb9931861305133b894fc40 328 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 322 2.9E-122 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS18395 e92cf30eefb9931861305133b894fc40 328 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 48.028 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.6E-88 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 PIRSF PIRSF000532 1 319 9.5E-125 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 SUPERFAMILY SSF53784 1 314 3.53E-117 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.7E-136 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 Pfam PF00365 Phosphofructokinase 3 275 1.7E-112 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 Gene3D G3DSA:3.40.50.450 1 213 4.0E-85 T 28-03-2018 A21D_RS14555 f6c829528f3eedeb3d74f888c7adc7bb 319 Gene3D G3DSA:3.40.50.450 214 309 8.6E-10 T 28-03-2018 A21D_RS15200 67b94d45f4d4e0d8b4ba7e4f58ef38bd 266 Gene3D G3DSA:3.40.50.300 2 242 7.0E-56 T 28-03-2018 A21D_RS15200 67b94d45f4d4e0d8b4ba7e4f58ef38bd 266 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 261 1.5E-122 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 A21D_RS15200 67b94d45f4d4e0d8b4ba7e4f58ef38bd 266 Pfam PF13614 AAA domain 4 161 4.8E-26 T 28-03-2018 IPR025669 AAA domain A21D_RS15200 67b94d45f4d4e0d8b4ba7e4f58ef38bd 266 PIRSF PIRSF003092 1 266 4.2E-93 T 28-03-2018 IPR025501 ATP binding protein MinD A21D_RS15200 67b94d45f4d4e0d8b4ba7e4f58ef38bd 266 SUPERFAMILY SSF52540 3 248 1.96E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 PIRSF PIRSF000498 1 199 6.7E-75 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 SUPERFAMILY SSF63380 1 90 3.57E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 SUPERFAMILY SSF63380 93 195 7.91E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 Gene3D G3DSA:2.40.30.20 1 93 3.9E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 Pfam PF00677 Lumazine binding domain 100 184 2.6E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 Pfam PF00677 Lumazine binding domain 3 87 8.1E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 Gene3D G3DSA:2.40.30.20 94 191 1.1E-29 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS11395 503d02cbb011c21b535448a5345bda50 199 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 3.2E-74 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 SUPERFAMILY SSF53383 26 436 5.01E-120 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 Gene3D G3DSA:3.90.1150.10 316 439 4.8E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 Gene3D G3DSA:3.40.640.10 54 315 6.3E-75 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 PIRSF PIRSF000521 8 439 1.4E-39 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 Pfam PF00202 Aminotransferase class-III 23 436 2.4E-106 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS09740 98a575d58b17e51549a9121bce62595e 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS15975 bd7981ea1928d5245b39e86a0e5664e3 371 Pfam PF00482 Type II secretion system (T2SS), protein F 45 157 9.1E-11 T 28-03-2018 IPR018076 Type II secretion system F domain A21D_RS15975 bd7981ea1928d5245b39e86a0e5664e3 371 Pfam PF00482 Type II secretion system (T2SS), protein F 241 363 6.4E-10 T 28-03-2018 IPR018076 Type II secretion system F domain A21D_RS15975 bd7981ea1928d5245b39e86a0e5664e3 371 PRINTS PR00812 Bacterial general secretion pathway protein F signature 135 163 5.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A21D_RS15975 bd7981ea1928d5245b39e86a0e5664e3 371 PRINTS PR00812 Bacterial general secretion pathway protein F signature 352 371 5.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A21D_RS02070 791a16c9000a3420189adf553bae74c2 475 PIRSF PIRSF006060 1 473 1.6E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS02070 791a16c9000a3420189adf553bae74c2 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 475 3.9E-189 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 A21D_RS02070 791a16c9000a3420189adf553bae74c2 475 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 6 475 5.1E-208 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 A21D_RS02070 791a16c9000a3420189adf553bae74c2 475 Pfam PF13520 Amino acid permease 8 422 1.2E-73 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS00335 9e78e042421814c84be5490f3e5c4e0b 112 SUPERFAMILY SSF103481 8 102 2.48E-15 T 28-03-2018 A21D_RS00335 9e78e042421814c84be5490f3e5c4e0b 112 Pfam PF00893 Small Multidrug Resistance protein 5 92 1.3E-20 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 Gene3D G3DSA:3.30.70.370 311 657 3.3E-34 T 28-03-2018 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 Pfam PF00476 DNA polymerase family A 230 650 7.8E-24 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 SUPERFAMILY SSF56672 530 657 5.56E-78 T 28-03-2018 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 SUPERFAMILY SSF56672 375 503 5.56E-78 T 28-03-2018 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 SUPERFAMILY SSF56672 192 346 5.56E-78 T 28-03-2018 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 Gene3D G3DSA:3.30.420.10 2 216 7.3E-13 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS00120 4af51397b19cfeaf753bcff187a1e7f0 658 SMART SM00482 372 623 4.2E-31 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 1.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 1.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 1.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 194 7.6E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 SUPERFAMILY SSF56784 2 228 5.47E-38 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 Gene3D G3DSA:1.10.150.240 14 86 0.0013 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 200 4.0E-29 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08535 89b54687b37ce8b910587c96c746db14 233 Gene3D G3DSA:3.40.50.1000 87 232 1.3E-28 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10175 6753c3e9d7b1c4d6706d31ca1349f629 149 SUPERFAMILY SSF52540 20 121 2.95E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10175 6753c3e9d7b1c4d6706d31ca1349f629 149 Gene3D G3DSA:3.40.50.300 1 149 4.8E-47 T 28-03-2018 A21D_RS10175 6753c3e9d7b1c4d6706d31ca1349f629 149 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 125 3.5E-38 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A21D_RS10175 6753c3e9d7b1c4d6706d31ca1349f629 149 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 132 5.6E-40 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 SUPERFAMILY SSF53720 10 489 1.57E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 Gene3D G3DSA:3.40.605.10 1 272 4.7E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 Gene3D G3DSA:3.40.309.10 273 471 9.4E-74 T 28-03-2018 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS07735 9b31fcec08786c50e3cd9a6abde3a8bc 497 Pfam PF00171 Aldehyde dehydrogenase family 23 485 1.1E-175 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS05860 b0ef45e01643da5a6124908c5c465e61 315 Gene3D G3DSA:3.40.50.1980 150 315 1.2E-33 T 28-03-2018 A21D_RS05860 b0ef45e01643da5a6124908c5c465e61 315 SUPERFAMILY SSF53807 38 310 1.41E-56 T 28-03-2018 A21D_RS05860 b0ef45e01643da5a6124908c5c465e61 315 Gene3D G3DSA:3.40.50.1980 36 149 1.5E-25 T 28-03-2018 A21D_RS05860 b0ef45e01643da5a6124908c5c465e61 315 Pfam PF01497 Periplasmic binding protein 57 289 1.2E-35 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 Pfam PF13531 Bacterial extracellular solute-binding protein 43 267 9.0E-37 T 28-03-2018 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 48 266 2.5E-48 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 PIRSF PIRSF004846 7 269 6.5E-62 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 Gene3D G3DSA:3.40.190.10 40 136 6.6E-16 T 28-03-2018 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 SUPERFAMILY SSF53850 41 267 4.48E-50 T 28-03-2018 A21D_RS07340 92d0257562798b6773c65d2fa86968ee 269 Gene3D G3DSA:3.40.190.10 137 228 3.6E-21 T 28-03-2018 A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 Gene3D G3DSA:3.40.50.300 3 337 2.0E-75 T 28-03-2018 A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 SMART SM00382 36 235 5.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 SUPERFAMILY SSF52540 35 312 1.86E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 Pfam PF00005 ABC transporter 28 185 2.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 1.8E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 7.4E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS10815 595c6b50e49c2edc54463ed4be21d221 342 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 267 4.1E-84 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 267 3.6E-32 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 PIRSF PIRSF000193 2 269 2.3E-77 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 Gene3D G3DSA:1.10.3730.10 161 269 3.5E-34 T 28-03-2018 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 100 2.2E-20 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 SUPERFAMILY SSF51735 3 161 5.87E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 Gene3D G3DSA:3.40.50.720 1 160 6.4E-25 T 28-03-2018 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 SUPERFAMILY SSF48179 162 268 8.16E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS07130 60d9af68844a61da6392697f10cf958c 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 267 25.529 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 Gene3D G3DSA:3.40.50.720 1 178 1.6E-24 T 28-03-2018 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 1.1E-39 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 Gene3D G3DSA:1.10.1040.10 179 310 9.8E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 SUPERFAMILY SSF48179 179 305 1.09E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 SUPERFAMILY SSF51735 1 128 6.73E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 304 2.0E-33 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS05905 7898db8f811eca22b0a7d83a8dd5b043 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 305 4.7E-81 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A21D_RS09930 10520bdd5842e2ccf417e7263955998d 297 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 293 2.7E-72 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase A21D_RS09930 10520bdd5842e2ccf417e7263955998d 297 SMART SM00046 6 132 4.3E-7 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A21D_RS09930 10520bdd5842e2ccf417e7263955998d 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 128 1.4E-26 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A21D_RS09930 10520bdd5842e2ccf417e7263955998d 297 SUPERFAMILY SSF111331 5 295 4.58E-63 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A21D_RS09930 10520bdd5842e2ccf417e7263955998d 297 Gene3D G3DSA:3.40.50.10330 1 133 3.2E-25 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 SUPERFAMILY SSF89447 1 136 6.8E-56 T 28-03-2018 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 5.9E-27 T 28-03-2018 IPR020603 MraZ domain A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 4.9E-25 T 28-03-2018 IPR020603 MraZ domain A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 1.3E-60 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 61.497 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 3.0E-56 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 Gene3D G3DSA:2.10.260.10 1 63 4.9E-7 T 28-03-2018 A21D_RS18430 0097a30cd78fecd97f96dbd39ac39d82 143 Gene3D G3DSA:2.10.260.10 74 124 9.5E-10 T 28-03-2018 A21D_RS18665 48993c5e77ec3c062c9b9073119a508c 360 Pfam PF00676 Dehydrogenase E1 component 42 332 1.2E-101 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A21D_RS18665 48993c5e77ec3c062c9b9073119a508c 360 SUPERFAMILY SSF52518 11 355 3.54E-104 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS18665 48993c5e77ec3c062c9b9073119a508c 360 Gene3D G3DSA:3.40.50.970 1 354 8.4E-87 T 28-03-2018 A21D_RS18665 48993c5e77ec3c062c9b9073119a508c 360 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 13 354 5.8E-148 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 Pfam PF00005 ABC transporter 18 174 1.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 1.6E-104 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 SUPERFAMILY SSF52540 1 239 1.3E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 Gene3D G3DSA:3.40.50.300 1 250 1.5E-60 T 28-03-2018 A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 SMART SM00382 27 223 2.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09920 09238eadb1528c9c7b12053cfd15cd08 258 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00320 f67bd6ecc0ab5bb4cb4a68bdf5218b8b 113 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 113 15.079 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A21D_RS00320 f67bd6ecc0ab5bb4cb4a68bdf5218b8b 113 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 108 5.8E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A21D_RS05785 9c99087b638e37bed879261377806705 249 Gene3D G3DSA:3.40.190.80 139 239 4.5E-9 T 28-03-2018 A21D_RS05785 9c99087b638e37bed879261377806705 249 SUPERFAMILY SSF56655 14 222 2.49E-38 T 28-03-2018 A21D_RS05785 9c99087b638e37bed879261377806705 249 Gene3D G3DSA:3.30.540.10 2 138 6.3E-26 T 28-03-2018 A21D_RS05785 9c99087b638e37bed879261377806705 249 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site A21D_RS05785 9c99087b638e37bed879261377806705 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.5E-12 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS05785 9c99087b638e37bed879261377806705 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 2.5E-12 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS05785 9c99087b638e37bed879261377806705 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.5E-12 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS05785 9c99087b638e37bed879261377806705 249 PRINTS PR00377 Inositol monophosphatase superfamily signature 166 187 2.5E-12 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS05785 9c99087b638e37bed879261377806705 249 Pfam PF00459 Inositol monophosphatase family 25 224 4.3E-30 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A21D_RS02705 5af715063f6cc7d65006b6a76ea38bd2 635 Gene3D G3DSA:1.20.120.670 411 628 4.6E-76 T 28-03-2018 A21D_RS02705 5af715063f6cc7d65006b6a76ea38bd2 635 SUPERFAMILY SSF51445 90 407 2.42E-54 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS02705 5af715063f6cc7d65006b6a76ea38bd2 635 Gene3D G3DSA:3.20.20.80 88 406 1.1E-57 T 28-03-2018 A21D_RS02705 5af715063f6cc7d65006b6a76ea38bd2 635 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 144 315 4.9E-13 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A21D_RS17465 23845f3dbb7a04c87e7a6d7b8360f1ac 131 SUPERFAMILY SSF47240 1 126 4.87E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS17465 23845f3dbb7a04c87e7a6d7b8360f1ac 131 Gene3D G3DSA:1.20.1260.10 1 127 1.6E-34 T 28-03-2018 IPR012347 Ferritin-related A21D_RS17465 23845f3dbb7a04c87e7a6d7b8360f1ac 131 Pfam PF05067 Manganese containing catalase 1 126 1.1E-48 T 28-03-2018 IPR007760 Manganese catalase A21D_RS02390 a1b34093eb80eba569434fa8e59af2d6 41 SUPERFAMILY SSF48295 1 33 4.18E-6 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A21D_RS02390 a1b34093eb80eba569434fa8e59af2d6 41 Gene3D G3DSA:1.10.10.10 1 35 1.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS02390 a1b34093eb80eba569434fa8e59af2d6 41 Pfam PF01527 Transposase 1 33 1.1E-5 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 Pfam PF00072 Response regulator receiver domain 6 118 1.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 258 1.4E-121 T 28-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 PIRSF PIRSF002937 1 258 4.3E-128 T 28-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 148 251 3.1E-45 T 28-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 SUPERFAMILY SSF46894 141 256 2.64E-49 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 SUPERFAMILY SSF52172 3 123 7.26E-32 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS16155 f870b679235fc992c9f188134023fd94 258 SMART SM00448 4 118 1.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 147 257 2.0E-56 T 28-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A21D_RS16155 f870b679235fc992c9f188134023fd94 258 Gene3D G3DSA:1.10.10.10 145 254 6.1E-54 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16155 f870b679235fc992c9f188134023fd94 258 Gene3D G3DSA:3.40.50.2300 3 144 7.3E-32 T 28-03-2018 A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 Gene3D G3DSA:3.40.50.880 1 201 3.2E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 SUPERFAMILY SSF52317 2 200 1.81E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 PIRSF PIRSF000495 1 201 1.1E-72 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 199 5.4E-73 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 Pfam PF00117 Glutamine amidotransferase class-I 4 196 6.6E-24 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS03040 cb188d4668f170942f4a8bf7863ce6d3 201 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 34.985 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A21D_RS04770 384672aba70a0b396cd69edcd60720e9 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 310 4.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04770 384672aba70a0b396cd69edcd60720e9 315 Gene3D G3DSA:1.10.3720.10 28 314 2.1E-35 T 28-03-2018 A21D_RS04770 384672aba70a0b396cd69edcd60720e9 315 SUPERFAMILY SSF161098 72 300 3.92E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS13070 228a37f3e310604aa015e0a03ec32046 65 Pfam PF14147 Sporulation protein YhaL 5 54 3.9E-22 T 28-03-2018 IPR025428 Sporulation protein YhaL A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 Gene3D G3DSA:3.10.105.10 365 573 1.4E-36 T 28-03-2018 A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 Gene3D G3DSA:3.40.190.10 216 364 2.1E-34 T 28-03-2018 A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 SUPERFAMILY SSF53850 70 593 3.72E-108 T 28-03-2018 A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 PIRSF PIRSF002741 3 601 9.0E-81 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 123 509 1.6E-81 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS07020 76ada4ab80343a3d90b4544679a11c7a 610 Gene3D G3DSA:3.90.76.10 107 215 4.1E-27 T 28-03-2018 A21D_RS05430 15cc7dfff3d2562326ebdb10100bc00b 74 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 1 74 1.0E-14 T 28-03-2018 IPR006479 Holin A21D_RS05430 15cc7dfff3d2562326ebdb10100bc00b 74 Pfam PF04688 SPP1 phage holin 1 69 5.9E-20 T 28-03-2018 IPR006479 Holin A21D_RS05430 15cc7dfff3d2562326ebdb10100bc00b 74 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 1 72 1.7E-23 T 28-03-2018 IPR006479 Holin A21D_RS16010 c572f8c7232334ae61a11a48100c3f33 485 SUPERFAMILY SSF53383 9 483 2.33E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS16010 c572f8c7232334ae61a11a48100c3f33 485 Gene3D G3DSA:3.40.640.10 83 344 4.7E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS16010 c572f8c7232334ae61a11a48100c3f33 485 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 59.108 T 28-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A21D_RS16010 c572f8c7232334ae61a11a48100c3f33 485 Gene3D G3DSA:3.90.1150.10 345 470 2.2E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS16010 c572f8c7232334ae61a11a48100c3f33 485 Pfam PF02347 Glycine cleavage system P-protein 36 300 1.6E-11 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 SUPERFAMILY SSF75445 129 206 9.42E-25 T 28-03-2018 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 Gene3D G3DSA:3.40.50.1360 1 140 1.0E-43 T 28-03-2018 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 SUPERFAMILY SSF100950 5 147 1.63E-44 T 28-03-2018 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 223 32.801 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 52 217 4.3E-67 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 Gene3D G3DSA:3.30.70.260 141 203 2.3E-29 T 28-03-2018 A21D_RS08505 af68fca0f6f358b2d3de330c2a48e18c 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 217 1.5E-82 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A21D_RS12080 5a4b5830335e4a395ca99085ce5ad937 243 Pfam PF02421 Ferrous iron transport protein B 4 158 6.0E-60 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A21D_RS12080 5a4b5830335e4a395ca99085ce5ad937 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.6E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS12080 5a4b5830335e4a395ca99085ce5ad937 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 1.6E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS12080 5a4b5830335e4a395ca99085ce5ad937 243 SUPERFAMILY SSF52540 4 191 5.08E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12080 5a4b5830335e4a395ca99085ce5ad937 243 Gene3D G3DSA:3.40.50.300 2 237 5.8E-33 T 28-03-2018 A21D_RS18240 8aad1f8df8882e43bda207ef0bc07133 568 Gene3D G3DSA:1.10.8.50 168 237 5.7E-16 T 28-03-2018 A21D_RS18240 8aad1f8df8882e43bda207ef0bc07133 568 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 443 3.7E-152 T 28-03-2018 A21D_RS18240 8aad1f8df8882e43bda207ef0bc07133 568 Pfam PF05670 Domain of unknown function (DUF814) 454 537 8.1E-30 T 28-03-2018 IPR008532 Domain of unknown function DUF814 A21D_RS18240 8aad1f8df8882e43bda207ef0bc07133 568 Gene3D G3DSA:3.40.970.40 241 288 7.1E-13 T 28-03-2018 A21D_RS18240 8aad1f8df8882e43bda207ef0bc07133 568 Gene3D G3DSA:2.30.310.10 1 167 1.3E-51 T 28-03-2018 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 SMART SM00934 4 227 1.0E-72 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 SUPERFAMILY SSF51366 4 232 4.71E-64 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 226 5.0E-42 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 7 228 3.2E-56 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 Gene3D G3DSA:3.20.20.70 2 231 2.2E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS18265 02cce5969ed2dfbe5967e861e9230378 236 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 232 35.471 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A21D_RS15945 3926f389a0c51837978c0df8ef924f12 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 80 3.0E-36 T 28-03-2018 IPR020254 Protein of unknown function DUF2626 A21D_RS15945 3926f389a0c51837978c0df8ef924f12 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 4.4E-37 T 28-03-2018 IPR020254 Protein of unknown function DUF2626 A21D_RS00840 f7c020a851c4ae3d7f39e85a3cbe14c7 149 SUPERFAMILY SSF141457 1 138 8.89E-45 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain A21D_RS00840 f7c020a851c4ae3d7f39e85a3cbe14c7 149 Gene3D G3DSA:2.30.290.10 1 146 2.4E-47 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain A21D_RS00840 f7c020a851c4ae3d7f39e85a3cbe14c7 149 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 23.931 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A21D_RS00840 f7c020a851c4ae3d7f39e85a3cbe14c7 149 Pfam PF02623 FliW protein 19 138 3.1E-37 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A21D_RS13950 825507064fff3f804e36bc37060d42b8 103 Pfam PF14068 Putative membrane protein 3 103 5.3E-40 T 28-03-2018 IPR025917 Putative membrane protein YuiB A21D_RS19355 b0a26dfb7fedd2b62f7638fc09f60caa 162 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 152 4.5E-26 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 SMART SM00642 13 415 4.0E-170 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Gene3D G3DSA:3.20.20.80 262 499 3.5E-65 T 28-03-2018 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 SUPERFAMILY SSF51445 3 473 2.92E-162 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 550 1.5E-11 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Pfam PF00128 Alpha amylase, catalytic domain 28 373 4.3E-121 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 SUPERFAMILY SSF51011 476 553 4.43E-19 T 28-03-2018 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 PRINTS PR00110 Alpha-amylase signature 92 103 1.7E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 PRINTS PR00110 Alpha-amylase signature 193 204 1.7E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 PRINTS PR00110 Alpha-amylase signature 316 328 1.7E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Gene3D G3DSA:2.60.40.1180 500 554 5.4E-11 T 28-03-2018 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Gene3D G3DSA:3.20.20.80 1 119 1.6E-48 T 28-03-2018 A21D_RS12680 057cdd20190cd2c1b65d7a7b554ce519 555 Gene3D G3DSA:3.90.400.10 120 174 1.8E-30 T 28-03-2018 A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 SUPERFAMILY SSF52540 1 223 4.82E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 6.5E-87 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 Pfam PF00005 ABC transporter 18 165 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 SMART SM00382 27 214 1.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00775 97ecf9d5ded3aba9f8cd53b1ccb5d818 228 Gene3D G3DSA:3.40.50.300 1 226 1.4E-63 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 Gene3D G3DSA:3.40.50.720 155 330 9.6E-16 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 285 2.6E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 9.8E-18 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 9.8E-18 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.8E-18 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.4E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.4E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.4E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.4E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 1.4E-19 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 Gene3D G3DSA:3.40.50.720 1 154 2.7E-15 T 28-03-2018 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 Hamap MF_01685 Ferredoxin--NADP reductase. 1 322 42.151 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A21D_RS01895 71193386d45cafbb661cfa1defad8e86 331 SUPERFAMILY SSF51905 1 304 7.78E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 Gene3D G3DSA:3.40.50.1860 118 214 9.7E-28 T 28-03-2018 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 SUPERFAMILY SSF53681 1 114 5.89E-37 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 SUPERFAMILY SSF53681 118 228 2.78E-33 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 232 4.4E-78 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 Gene3D G3DSA:3.40.50.1860 1 117 5.2E-33 T 28-03-2018 A21D_RS07845 6904fd404c535e2a9ea1dea6054258f5 233 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 1.6E-60 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 10 236 2.9E-86 T 28-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 Gene3D G3DSA:1.10.287.90 25 111 1.5E-20 T 28-03-2018 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 PIRSF PIRSF000292 1 309 2.4E-100 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 Gene3D G3DSA:2.60.40.420 112 316 5.3E-37 T 28-03-2018 IPR008972 Cupredoxin A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 SUPERFAMILY SSF81464 15 112 1.8E-17 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 32 107 2.3E-5 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS09790 e5b27cef48fe7dc37a4a691c02d22813 321 SUPERFAMILY SSF49503 122 269 6.98E-40 T 28-03-2018 IPR008972 Cupredoxin A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 69 197 5.3E-53 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Gene3D G3DSA:3.40.50.10860 73 202 2.3E-56 T 28-03-2018 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 PIRSF PIRSF000185 32 460 2.1E-127 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 SUPERFAMILY SSF51735 215 459 3.95E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 206 228 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 248 268 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 126 140 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 384 395 2.3E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 SMART SM00839 217 458 6.5E-92 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Gene3D G3DSA:3.40.50.720 222 385 3.9E-44 T 28-03-2018 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Gene3D G3DSA:1.10.285.10 386 460 3.9E-26 T 28-03-2018 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Gene3D G3DSA:1.10.285.10 18 72 1.9E-10 T 28-03-2018 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 215 458 1.6E-86 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS12600 71cb0abfcd557ebaad6a7487d9862e35 460 SUPERFAMILY SSF53223 18 209 8.32E-76 T 28-03-2018 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 3.9E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 3.9E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 3.9E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 3.9E-31 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 SMART SM01350 167 294 2.0E-6 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 SUPERFAMILY SSF48179 165 297 2.04E-40 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 Gene3D G3DSA:1.10.1040.10 169 297 8.8E-38 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 6.9E-131 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 2.0E-43 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 Gene3D G3DSA:3.40.50.720 1 168 8.5E-27 T 28-03-2018 A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 SUPERFAMILY SSF51735 1 155 9.49E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS08915 922c3ca24c3b03f824cf642993fccd6c 299 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 275 6.3E-25 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS08055 4917d7982bf476e5361e04fa0d3d1d88 225 Gene3D G3DSA:3.30.1330.90 19 144 2.2E-19 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS08055 4917d7982bf476e5361e04fa0d3d1d88 225 PIRSF PIRSF036692 7 225 6.7E-57 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS08055 4917d7982bf476e5361e04fa0d3d1d88 225 SUPERFAMILY SSF143548 25 142 1.01E-25 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS08055 4917d7982bf476e5361e04fa0d3d1d88 225 Pfam PF03315 Serine dehydratase beta chain 12 88 3.1E-11 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS04820 ed389fa99bde04a240b41975a3df8ced 248 SUPERFAMILY SSF54909 4 247 2.23E-84 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS04820 ed389fa99bde04a240b41975a3df8ced 248 Hamap MF_01442 Putative heme-dependent peroxidase . 1 248 52.002 T 28-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family A21D_RS04820 ed389fa99bde04a240b41975a3df8ced 248 Pfam PF06778 Chlorite dismutase 33 236 1.0E-69 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase A21D_RS04820 ed389fa99bde04a240b41975a3df8ced 248 Gene3D G3DSA:3.30.70.1100 139 244 1.7E-27 T 28-03-2018 A21D_RS04820 ed389fa99bde04a240b41975a3df8ced 248 Gene3D G3DSA:3.30.70.1030 4 136 6.8E-38 T 28-03-2018 A21D_RS10025 e24e80966636cd37fa0e62e2dca93389 119 Gene3D G3DSA:2.30.30.110 1 116 4.6E-38 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A21D_RS10025 e24e80966636cd37fa0e62e2dca93389 119 PIRSF PIRSF033490 1 113 2.0E-36 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A21D_RS10025 e24e80966636cd37fa0e62e2dca93389 119 SUPERFAMILY SSF50118 2 114 2.78E-39 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A21D_RS10025 e24e80966636cd37fa0e62e2dca93389 119 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 110 2.4E-32 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A21D_RS11570 516d5afe98dd381ed5803f961047e0df 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 223 4.8E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS11570 516d5afe98dd381ed5803f961047e0df 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 117 4.7E-30 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A21D_RS11570 516d5afe98dd381ed5803f961047e0df 231 SUPERFAMILY SSF161098 22 208 1.44E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS11570 516d5afe98dd381ed5803f961047e0df 231 Gene3D G3DSA:1.10.3720.10 15 225 4.0E-45 T 28-03-2018 A21D_RS13855 6e31f55a332fcb1953ca4c1936e5e902 518 Pfam PF03553 Na+/H+ antiporter family 160 486 4.1E-79 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS17005 a160f4d63c8c81184c83058ffc086ae5 229 SUPERFAMILY SSF56281 20 228 3.93E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS17005 a160f4d63c8c81184c83058ffc086ae5 229 SMART SM00849 19 223 2.6E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS17005 a160f4d63c8c81184c83058ffc086ae5 229 Pfam PF00753 Metallo-beta-lactamase superfamily 22 223 2.3E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS17005 a160f4d63c8c81184c83058ffc086ae5 229 Gene3D G3DSA:3.60.15.10 14 229 3.2E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS04870 07464acaaff1f430eca72910fd0e1fae 1079 Gene3D G3DSA:1.50.10.10 564 941 8.3E-35 T 28-03-2018 A21D_RS04870 07464acaaff1f430eca72910fd0e1fae 1079 Gene3D G3DSA:2.70.98.40 1 223 6.5E-26 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A21D_RS04870 07464acaaff1f430eca72910fd0e1fae 1079 Gene3D G3DSA:2.60.420.10 983 1079 9.1E-8 T 28-03-2018 A21D_RS04870 07464acaaff1f430eca72910fd0e1fae 1079 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 650 938 1.7E-16 T 28-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain A21D_RS04870 07464acaaff1f430eca72910fd0e1fae 1079 SUPERFAMILY SSF48208 527 1045 2.45E-42 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 SUPERFAMILY SSF117074 482 561 1.18E-6 T 28-03-2018 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 Gene3D G3DSA:2.60.40.10 167 276 3.0E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 581 613 2.4E-7 T 28-03-2018 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 SUPERFAMILY SSF49478 174 248 1.45E-9 T 28-03-2018 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 282 408 2.1E-22 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 Gene3D G3DSA:2.60.40.810 26 166 3.4E-9 T 28-03-2018 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 Gene3D G3DSA:2.60.40.810 450 586 2.1E-21 T 28-03-2018 A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 Pfam PF00746 LPXTG cell wall anchor motif 581 613 7.6E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor A21D_RS01755 7aee86fca62df50e0d2405fc7eab91d1 618 Gene3D G3DSA:2.60.40.740 283 429 5.4E-21 T 28-03-2018 A21D_RS11775 99a5a5940c444f9864df6774394ea12e 288 Gene3D G3DSA:1.10.10.10 233 284 2.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11775 99a5a5940c444f9864df6774394ea12e 288 Pfam PF14540 Nucleotidyltransferase-like 1 118 2.8E-44 T 28-03-2018 IPR029348 Nucleotidyltransferase-like domain A21D_RS11775 99a5a5940c444f9864df6774394ea12e 288 Gene3D G3DSA:1.20.120.330 118 231 1.4E-39 T 28-03-2018 A21D_RS11775 99a5a5940c444f9864df6774394ea12e 288 Gene3D G3DSA:3.30.460.10 1 114 1.1E-42 T 28-03-2018 A21D_RS11775 99a5a5940c444f9864df6774394ea12e 288 ProDom PD128250 YGXA BH0953 1 275 5.0E-95 T 28-03-2018 A21D_RS09240 9b20ed2cb04f5cd827a6386d59541545 370 Gene3D G3DSA:3.40.50.1820 4 370 2.2E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS09240 9b20ed2cb04f5cd827a6386d59541545 370 Pfam PF00561 alpha/beta hydrolase fold 42 248 1.0E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS09240 9b20ed2cb04f5cd827a6386d59541545 370 SUPERFAMILY SSF53474 5 369 2.95E-71 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS09240 9b20ed2cb04f5cd827a6386d59541545 370 PIRSF PIRSF000443 1 370 2.3E-101 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 A21D_RS02775 53118e27d02b7f6ca2b3e9fc24a8caf0 397 Gene3D G3DSA:1.20.1250.20 10 200 8.9E-19 T 28-03-2018 A21D_RS02775 53118e27d02b7f6ca2b3e9fc24a8caf0 397 SUPERFAMILY SSF103473 20 396 2.75E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS02775 53118e27d02b7f6ca2b3e9fc24a8caf0 397 Pfam PF07690 Major Facilitator Superfamily 28 351 3.5E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS02775 53118e27d02b7f6ca2b3e9fc24a8caf0 397 Gene3D G3DSA:1.20.1250.20 204 397 2.6E-13 T 28-03-2018 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 SUPERFAMILY SSF47384 216 295 1.96E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 3.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 3.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 3.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 3.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 SMART SM00388 232 296 3.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 SUPERFAMILY SSF55874 285 452 6.68E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 SMART SM00387 342 454 5.5E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 Gene3D G3DSA:3.30.565.10 300 456 9.9E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 Gene3D G3DSA:1.10.287.130 222 290 5.4E-11 T 28-03-2018 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 288 2.8E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS12100 c2c578438ec4316a805384e428d6daf6 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 452 3.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10990 a446d20f0197e1059ed98bdd2613bde7 98 Pfam PF01371 Trp repressor protein 9 93 1.2E-33 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 A21D_RS10990 a446d20f0197e1059ed98bdd2613bde7 98 SUPERFAMILY SSF48295 3 95 2.82E-31 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A21D_RS10990 a446d20f0197e1059ed98bdd2613bde7 98 Gene3D G3DSA:1.10.1270.10 1 98 3.3E-32 T 28-03-2018 A21D_RS10990 a446d20f0197e1059ed98bdd2613bde7 98 PIRSF PIRSF012508 1 98 4.5E-47 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD A21D_RS10990 a446d20f0197e1059ed98bdd2613bde7 98 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 1.2E-48 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD A21D_RS12890 5f47241d67df5970edde549571d1d587 323 Gene3D G3DSA:3.30.420.10 148 318 4.3E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12890 5f47241d67df5970edde549571d1d587 323 Pfam PF00665 Integrase core domain 161 265 5.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS12890 5f47241d67df5970edde549571d1d587 323 SUPERFAMILY SSF53098 160 309 1.86E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS12890 5f47241d67df5970edde549571d1d587 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 8.8E-117 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 Gene3D G3DSA:2.40.30.40 72 163 3.1E-35 T 28-03-2018 IPR023367 Peptidase M42, domain 2 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 PIRSF PIRSF001123 4 361 1.0E-146 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 SUPERFAMILY SSF53187 6 83 1.31E-73 T 28-03-2018 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 SUPERFAMILY SSF53187 174 356 1.31E-73 T 28-03-2018 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 Gene3D G3DSA:3.40.630.10 172 359 8.5E-45 T 28-03-2018 A21D_RS14705 94a54b8285f3830444a5293c49d33444 361 SUPERFAMILY SSF101821 73 182 3.21E-33 T 28-03-2018 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 PIRSF PIRSF001338 1 161 8.3E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 Pfam PF00731 AIR carboxylase 2 149 1.3E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 2 158 8.6E-68 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 Gene3D G3DSA:3.40.50.7700 1 160 2.6E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 2 155 32.843 T 28-03-2018 IPR033747 Class I PurE A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 SUPERFAMILY SSF52255 2 158 8.24E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A21D_RS10920 e067ce9a8e56c1a2ed1115dfa7f49aa9 161 SMART SM01001 1 151 5.4E-100 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 Pfam PF00453 Ribosomal protein L20 3 109 6.9E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.075 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 SUPERFAMILY SSF74731 2 117 1.57E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 9.4E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 9.4E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 9.4E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-14 T 28-03-2018 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 Gene3D G3DSA:1.10.1900.20 55 116 7.8E-29 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14680 22c6370ba4e8161fb4767ee1704a3927 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 8.0E-51 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS08365 7c98f4a7d7ad7a7c3a9ac0d45c4d59cb 142 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 135 4.3E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS08365 7c98f4a7d7ad7a7c3a9ac0d45c4d59cb 142 SUPERFAMILY SSF52788 6 137 2.88E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS08365 7c98f4a7d7ad7a7c3a9ac0d45c4d59cb 142 SMART SM00226 4 138 6.2E-45 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS08365 7c98f4a7d7ad7a7c3a9ac0d45c4d59cb 142 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 135 8.4E-66 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 A21D_RS08365 7c98f4a7d7ad7a7c3a9ac0d45c4d59cb 142 Gene3D G3DSA:3.40.50.2300 1 138 3.6E-40 T 28-03-2018 A21D_RS12290 0653fe0c5bd1ce29314758130c200e70 330 SUPERFAMILY SSF51556 3 328 2.77E-72 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS12290 0653fe0c5bd1ce29314758130c200e70 330 Gene3D G3DSA:3.20.20.140 1 327 2.3E-47 T 28-03-2018 A21D_RS12290 0653fe0c5bd1ce29314758130c200e70 330 PIRSF PIRSF016839 1 330 1.5E-72 T 28-03-2018 A21D_RS12290 0653fe0c5bd1ce29314758130c200e70 330 Pfam PF02126 Phosphotriesterase family 11 327 1.4E-49 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 A21D_RS14030 8e4e7a05567c44de74d53e8351169d09 185 Pfam PF14595 Thioredoxin 10 136 1.5E-42 T 28-03-2018 A21D_RS14030 8e4e7a05567c44de74d53e8351169d09 185 Gene3D G3DSA:3.40.30.10 1 164 1.2E-16 T 28-03-2018 A21D_RS14030 8e4e7a05567c44de74d53e8351169d09 185 SUPERFAMILY SSF52833 45 142 7.49E-10 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS18920 20701fe227682a351b06775f9c46257e 404 SUPERFAMILY SSF51905 158 338 5.56E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 324 4.9E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 4.9E-7 T 28-03-2018 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 4.9E-7 T 28-03-2018 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 4.9E-7 T 28-03-2018 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.9E-7 T 28-03-2018 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 Gene3D G3DSA:3.50.50.60 149 380 6.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 SUPERFAMILY SSF51905 5 211 7.92E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18920 20701fe227682a351b06775f9c46257e 404 Gene3D G3DSA:3.50.50.60 4 138 2.5E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 SUPERFAMILY SSF53335 1 179 5.02E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 175 6.5E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 PIRSF PIRSF004553 1 184 1.3E-48 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 Pfam PF03602 Conserved hypothetical protein 95 1 179 4.2E-55 T 28-03-2018 A21D_RS18485 115167f7243ba39aa04c0da9455c1fc6 184 Gene3D G3DSA:3.40.50.150 1 184 1.3E-32 T 28-03-2018 A21D_RS06040 58194d811b5bfa5a7ab3c28889d48465 225 Pfam PF02361 Cobalt transport protein 2 193 2.5E-8 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A21D_RS03775 62c8b922e0a9de7e0d439b70e47ef51f 200 SUPERFAMILY SSF53474 2 198 2.24E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03775 62c8b922e0a9de7e0d439b70e47ef51f 200 Pfam PF02230 Phospholipase/Carboxylesterase 6 196 9.5E-9 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 A21D_RS03775 62c8b922e0a9de7e0d439b70e47ef51f 200 Gene3D G3DSA:3.40.50.1820 1 199 1.4E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS15805 457092e118072f5853a3b37d92440bea 115 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 52 105 4.0E-6 T 28-03-2018 IPR020506 Uncharacterised protein family YqfZ A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 Gene3D G3DSA:3.90.640.10 191 248 3.3E-32 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 SUPERFAMILY SSF53067 144 326 2.25E-46 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 SUPERFAMILY SSF53067 6 141 1.43E-36 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 Gene3D G3DSA:3.30.420.40 2 155 2.4E-39 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 1.8E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 1.8E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.8E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.8E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.8E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 Gene3D G3DSA:3.30.420.40 156 190 0.65 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 Gene3D G3DSA:3.30.420.40 249 312 4.1E-7 T 28-03-2018 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 Pfam PF06723 MreB/Mbl protein 5 331 1.4E-142 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS11525 6dd292cbe5c823bf6404da8a7ac6acee 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 331 6.8E-139 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS08080 1d26390d1026f3b31219f7f4e5236145 207 Pfam PF07875 Coat F domain 121 183 4.5E-16 T 28-03-2018 IPR012851 Spore coat protein CotF-like A21D_RS08080 1d26390d1026f3b31219f7f4e5236145 207 Gene3D G3DSA:1.20.1260.10 14 179 3.9E-23 T 28-03-2018 IPR012347 Ferritin-related A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 Gene3D G3DSA:3.90.226.10 3 201 3.3E-32 T 28-03-2018 A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 SUPERFAMILY SSF52096 12 187 4.33E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 PRINTS PR00127 Clp protease catalytic subunit P signature 85 102 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 PRINTS PR00127 Clp protease catalytic subunit P signature 161 180 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 PRINTS PR00127 Clp protease catalytic subunit P signature 54 74 7.5E-11 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00035 7ef8990441f474a63a268e2fbde8f654 246 Pfam PF00574 Clp protease 40 184 3.4E-31 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A21D_RS05460 c240fc673deda40ea642cad0abc6535e 157 Gene3D G3DSA:1.20.5.730 80 150 0.001 T 28-03-2018 A21D_RS05460 c240fc673deda40ea642cad0abc6535e 157 Gene3D G3DSA:1.20.5.730 14 79 9.7E-6 T 28-03-2018 A21D_RS18300 1a46df7b270e3a6690afa35457dadb08 181 SUPERFAMILY SSF53271 8 172 2.88E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS18300 1a46df7b270e3a6690afa35457dadb08 181 Pfam PF00156 Phosphoribosyl transferase domain 7 152 1.4E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS18300 1a46df7b270e3a6690afa35457dadb08 181 Gene3D G3DSA:3.40.50.2020 1 181 1.0E-35 T 28-03-2018 A21D_RS18300 1a46df7b270e3a6690afa35457dadb08 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 37.196 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 Gene3D G3DSA:3.30.420.40 153 188 9.1E-4 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 8.1E-57 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 8.1E-57 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 8.1E-57 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 8.1E-57 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 8.1E-57 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 Gene3D G3DSA:3.90.640.10 189 244 4.6E-29 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 Gene3D G3DSA:3.30.420.40 1 152 7.2E-34 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 SUPERFAMILY SSF53067 143 325 2.77E-50 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 Gene3D G3DSA:3.30.420.40 245 309 3.4E-8 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 Pfam PF06723 MreB/Mbl protein 4 328 4.1E-150 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 SUPERFAMILY SSF53067 2 140 1.94E-37 T 28-03-2018 A21D_RS04460 2c65f8ca800a89d5bae092078f10d492 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 328 3.6E-136 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 Gene3D G3DSA:3.40.50.300 24 283 3.2E-61 T 28-03-2018 A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 SUPERFAMILY SSF52540 29 272 1.21E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 SMART SM00382 63 257 8.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 39 285 2.5E-125 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A21D_RS08600 fbb39194bbeab28ba255b8335384c7b9 285 Pfam PF00005 ABC transporter 54 210 4.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07805 628539f40ba171ac41743d99d2718e17 281 Pfam PF00005 ABC transporter 17 148 7.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07805 628539f40ba171ac41743d99d2718e17 281 SUPERFAMILY SSF52540 2 204 2.03E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07805 628539f40ba171ac41743d99d2718e17 281 Gene3D G3DSA:3.40.50.300 1 262 4.3E-49 T 28-03-2018 A21D_RS07805 628539f40ba171ac41743d99d2718e17 281 SMART SM00382 26 197 5.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08015 aab33995ab64b126043254d16363a02a 412 Pfam PF02378 Phosphotransferase system, EIIC 21 335 5.1E-42 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS08015 aab33995ab64b126043254d16363a02a 412 PIRSF PIRSF006351 1 412 1.8E-121 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS08015 aab33995ab64b126043254d16363a02a 412 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 4 409 2.5E-93 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS09870 528ffa5b6bd178180bd65e34a1a58031 208 SUPERFAMILY SSF54593 3 114 1.56E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS09870 528ffa5b6bd178180bd65e34a1a58031 208 Gene3D G3DSA:3.10.180.10 1 145 1.0E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS09870 528ffa5b6bd178180bd65e34a1a58031 208 Pfam PF13468 Glyoxalase-like domain 4 155 1.1E-33 T 28-03-2018 IPR025870 Glyoxalase-like domain A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 SUPERFAMILY SSF50156 127 214 1.45E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 Pfam PF13180 PDZ domain 127 194 6.3E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 SUPERFAMILY SSF54211 215 332 6.07E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 Gene3D G3DSA:3.30.230.10 41 336 8.2E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 230 329 1.8E-11 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A21D_RS18470 7dbf1075f83b8e9fae3dad4c1accde81 336 SMART SM00228 94 185 7.0E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS07275 2d1d1b21a51286c9b6fcc82bf7fad702 257 PIRSF PIRSF009320 90 256 1.5E-8 T 28-03-2018 A21D_RS07275 2d1d1b21a51286c9b6fcc82bf7fad702 257 PIRSF PIRSF009320 2 76 2.1E-15 T 28-03-2018 A21D_RS07275 2d1d1b21a51286c9b6fcc82bf7fad702 257 Gene3D G3DSA:3.40.50.300 1 257 7.0E-61 T 28-03-2018 A21D_RS07275 2d1d1b21a51286c9b6fcc82bf7fad702 257 Pfam PF13614 AAA domain 2 178 1.8E-72 T 28-03-2018 IPR025669 AAA domain A21D_RS07275 2d1d1b21a51286c9b6fcc82bf7fad702 257 SUPERFAMILY SSF52540 1 252 6.62E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13965 6960af380dda2292fcaa12e86aaab780 199 PIRSF PIRSF016661 1 195 7.1E-39 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS13965 6960af380dda2292fcaa12e86aaab780 199 Pfam PF02632 BioY family 41 185 1.2E-33 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 SUPERFAMILY SSF53850 2 255 3.06E-67 T 28-03-2018 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 Gene3D G3DSA:3.40.190.10 2 149 1.4E-44 T 28-03-2018 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 Gene3D G3DSA:3.40.190.10 150 258 1.3E-15 T 28-03-2018 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 SMART SM00062 38 257 8.0E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 SMART SM00079 38 256 3.7E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A21D_RS02920 c905f76c1fd0c0f7bd9da51a4e1dd9c8 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 255 5.2E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS04350 24e4ab891c15a7d1e0ff676114cdec24 232 Gene3D G3DSA:3.20.20.70 1 230 2.0E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS04350 24e4ab891c15a7d1e0ff676114cdec24 232 SUPERFAMILY SSF51366 5 223 2.1E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS04350 24e4ab891c15a7d1e0ff676114cdec24 232 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 4 226 40.586 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 A21D_RS04350 24e4ab891c15a7d1e0ff676114cdec24 232 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 28 226 3.5E-66 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 A21D_RS05345 f8a2437178ea9cf9756f66c02983e3d7 337 Pfam PF13531 Bacterial extracellular solute-binding protein 50 291 5.3E-26 T 28-03-2018 A21D_RS05345 f8a2437178ea9cf9756f66c02983e3d7 337 Gene3D G3DSA:3.40.190.10 1 190 7.0E-23 T 28-03-2018 A21D_RS05345 f8a2437178ea9cf9756f66c02983e3d7 337 Gene3D G3DSA:3.40.190.10 191 314 1.4E-22 T 28-03-2018 A21D_RS05345 f8a2437178ea9cf9756f66c02983e3d7 337 SUPERFAMILY SSF53850 36 331 4.23E-62 T 28-03-2018 A21D_RS05345 f8a2437178ea9cf9756f66c02983e3d7 337 PIRSF PIRSF002825 1 335 1.1E-64 T 28-03-2018 IPR026045 Ferric binding protein A21D_RS00305 ad294c04350db139574e31886e0ce82e 278 SUPERFAMILY SSF81345 4 266 1.24E-36 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS00305 ad294c04350db139574e31886e0ce82e 278 Gene3D G3DSA:1.10.3470.10 6 277 1.3E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS00305 ad294c04350db139574e31886e0ce82e 278 Pfam PF00950 ABC 3 transport family 8 269 3.1E-65 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 Gene3D G3DSA:3.10.20.10 28 109 3.8E-16 T 28-03-2018 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 SUPERFAMILY SSF53927 7 259 3.61E-72 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 PIRSF PIRSF015626 3 262 9.5E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 260 30.029 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 24 260 9.2E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 Gene3D G3DSA:3.40.140.10 125 263 6.9E-47 T 28-03-2018 A21D_RS08795 5fce150f32264595f6b034f11afa12ff 267 Pfam PF02634 FdhD/NarQ family 26 259 2.6E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A21D_RS06880 aa03a49ab5d09387e9477c54a9f230ee 88 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 9.2E-27 T 28-03-2018 IPR010001 SigmaK-factor processing regulatory BofA A21D_RS06880 aa03a49ab5d09387e9477c54a9f230ee 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 11 85 5.9E-17 T 28-03-2018 IPR010001 SigmaK-factor processing regulatory BofA A21D_RS04360 aeb300e5395a9227246202706ad8773a 341 Pfam PF01170 Putative RNA methylase family UPF0020 165 299 1.9E-23 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A21D_RS04360 aeb300e5395a9227246202706ad8773a 341 Gene3D G3DSA:3.40.50.150 161 341 2.6E-24 T 28-03-2018 A21D_RS04360 aeb300e5395a9227246202706ad8773a 341 SUPERFAMILY SSF53335 146 295 7.49E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 Pfam PF01022 Bacterial regulatory protein, arsR family 19 65 8.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 SMART SM00418 12 90 9.7E-25 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 Gene3D G3DSA:1.10.10.10 1 99 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS10875 44bf9ee2e40239ea0401f4f74f0c3620 99 SUPERFAMILY SSF46785 3 92 2.98E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 Pfam PF00155 Aminotransferase class I and II 53 382 2.3E-41 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 Gene3D G3DSA:3.40.640.10 101 278 4.8E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 SUPERFAMILY SSF53383 2 387 4.92E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 Gene3D G3DSA:3.90.1150.10 279 385 2.2E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 387 5.8E-157 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A21D_RS14000 de54130fae3bcae6a4ad48c9dae00853 389 Gene3D G3DSA:3.90.1150.10 2 100 6.5E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 SMART SM00388 239 306 1.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 8.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 483 1.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 Gene3D G3DSA:1.10.287.130 229 300 2.6E-14 T 28-03-2018 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 5.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 SUPERFAMILY SSF47384 222 304 7.06E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 SUPERFAMILY SSF55874 295 482 4.85E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 SMART SM00387 351 484 1.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS19500 68d7222466a0539b35d31ea3ef9270b8 486 Gene3D G3DSA:3.30.565.10 301 484 6.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 147 335 4.6E-52 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 SMART SM00331 120 335 1.3E-57 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 SUPERFAMILY SSF81606 129 334 3.01E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 SMART SM00332 118 333 0.0024 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 SUPERFAMILY SSF101215 8 84 1.18E-22 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 1 94 5.0E-21 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 11 84 1.6E-23 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 Gene3D G3DSA:1.10.1240.30 9 84 2.5E-22 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 A21D_RS10045 8371ead872aa4b0017b1c58df5d5cd45 337 Gene3D G3DSA:3.60.40.10 86 337 2.4E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 SUPERFAMILY SSF52418 74 335 1.57E-86 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 Pfam PF00591 Glycosyl transferase family, a/b domain 72 323 3.4E-85 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 35.513 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 SUPERFAMILY SSF47648 1 64 6.54E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 63 5.6E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 Gene3D G3DSA:3.40.1030.10 69 342 1.2E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 331 1.9E-111 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A21D_RS03230 0928b7707a34f10b3266785263b4c4b9 342 Gene3D G3DSA:1.20.970.10 1 65 2.7E-16 T 28-03-2018 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 SUPERFAMILY SSF161098 13 200 1.7E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 238 501 2.4E-56 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 Gene3D G3DSA:3.40.190.10 229 388 2.9E-32 T 28-03-2018 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 Gene3D G3DSA:1.10.3720.10 1 211 5.2E-30 T 28-03-2018 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 SUPERFAMILY SSF53850 238 505 2.82E-68 T 28-03-2018 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 205 1.2E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS17060 623430b43a3a7063ab8abe9e929350bc 507 Gene3D G3DSA:3.40.190.10 389 505 2.3E-20 T 28-03-2018 A21D_RS15070 68b92b5a57af7c99478db4c2c648535c 196 Gene3D G3DSA:1.10.3210.10 1 195 1.6E-38 T 28-03-2018 A21D_RS15070 68b92b5a57af7c99478db4c2c648535c 196 SUPERFAMILY SSF109604 6 162 4.32E-34 T 28-03-2018 A21D_RS15070 68b92b5a57af7c99478db4c2c648535c 196 Pfam PF13023 HD domain 16 173 3.7E-46 T 28-03-2018 IPR006674 HD domain A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 Gene3D G3DSA:1.20.5.1150 17 53 2.4E-18 T 28-03-2018 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 14 26 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 Pfam PF01165 Ribosomal protein S21 6 58 8.4E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 57 2.1E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 PRINTS PR00976 Ribosomal protein S21 family signature 6 14 8.5E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 PRINTS PR00976 Ribosomal protein S21 family signature 14 23 8.5E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 PRINTS PR00976 Ribosomal protein S21 family signature 26 36 8.5E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 PRINTS PR00976 Ribosomal protein S21 family signature 38 48 8.5E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 2 58 17.592 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS15670 eebfd6af4d2b1fc40d3fd5e68a2559bc 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 17 44 4.0E-9 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS01785 79261ca7d0bd02c1ae9b0a73c9b5592f 450 Gene3D G3DSA:3.40.309.10 236 408 1.5E-28 T 28-03-2018 A21D_RS01785 79261ca7d0bd02c1ae9b0a73c9b5592f 450 SUPERFAMILY SSF53720 14 449 1.31E-84 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS01785 79261ca7d0bd02c1ae9b0a73c9b5592f 450 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 13 448 2.4E-197 T 28-03-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating A21D_RS01785 79261ca7d0bd02c1ae9b0a73c9b5592f 450 Gene3D G3DSA:3.40.605.10 6 235 5.8E-30 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS01785 79261ca7d0bd02c1ae9b0a73c9b5592f 450 Pfam PF00171 Aldehyde dehydrogenase family 12 405 2.4E-31 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.352 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 Pfam PF00574 Clp protease 13 192 2.0E-88 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 SUPERFAMILY SSF52096 10 192 1.76E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.5E-107 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 Gene3D G3DSA:3.90.226.10 2 194 4.2E-46 T 28-03-2018 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 7.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 7.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 7.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 7.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS00640 40b0f23ee75b324e3b25a6eaee8ce598 195 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 7.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A21D_RS19305 a25df5bfa5db451a4430edfaefa2c104 248 Pfam PF01925 Sulfite exporter TauE/SafE 13 245 4.4E-25 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A21D_RS00975 dc76c3757a4f1017ba2af07c0acef6e2 392 Pfam PF07690 Major Facilitator Superfamily 8 233 2.2E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS00975 dc76c3757a4f1017ba2af07c0acef6e2 392 Gene3D G3DSA:1.20.1250.20 2 182 1.2E-22 T 28-03-2018 A21D_RS00975 dc76c3757a4f1017ba2af07c0acef6e2 392 Gene3D G3DSA:1.20.1250.20 199 382 2.8E-22 T 28-03-2018 A21D_RS00975 dc76c3757a4f1017ba2af07c0acef6e2 392 SUPERFAMILY SSF103473 3 379 1.31E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.381 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 4.7E-24 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 SUPERFAMILY SSF57840 1 37 5.62E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 Pfam PF00444 Ribosomal protein L36 1 37 5.3E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06255 d7783bcfe2fb6a1976c87d60e3cdff37 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 5.0E-8 T 28-03-2018 A21D_RS11010 ef7de6cec2127aa107536665dcd112d6 365 Gene3D G3DSA:3.10.570.10 33 365 4.3E-129 T 28-03-2018 A21D_RS11010 ef7de6cec2127aa107536665dcd112d6 365 PIRSF PIRSF012509 1 365 3.7E-133 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 A21D_RS11010 ef7de6cec2127aa107536665dcd112d6 365 Pfam PF07537 CamS sex pheromone cAM373 precursor 54 358 6.7E-112 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.4E-58 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 142 1.6E-53 T 28-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 PIRSF PIRSF005384 1 146 4.9E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 Pfam PF02502 Ribose/Galactose Isomerase 3 140 4.2E-55 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 SUPERFAMILY SSF89623 1 144 9.81E-58 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS04605 409ead55392435910c6e1ec56b64094a 148 Gene3D G3DSA:3.40.1400.10 1 148 2.8E-65 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 SUPERFAMILY SSF52540 182 432 1.06E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 441 2.5E-185 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 Gene3D G3DSA:1.10.860.10 1 150 2.1E-47 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 SUPERFAMILY SSF48024 7 118 1.7E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 Pfam PF00772 DnaB-like helicase N terminal domain 9 110 2.3E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 Pfam PF03796 DnaB-like helicase C terminal domain 184 438 2.6E-118 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A21D_RS07365 5379e64a91259ad0d4b0b6abeb9ceee6 452 Gene3D G3DSA:3.40.50.300 166 452 1.5E-79 T 28-03-2018 A21D_RS13315 07142bc4f82e452e16cd815578528377 66 Pfam PF10803 Spore germination GerPB 1 52 1.8E-26 T 28-03-2018 IPR024255 Spore germination GerPB A21D_RS13315 07142bc4f82e452e16cd815578528377 66 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 50 5.0E-5 T 28-03-2018 IPR024255 Spore germination GerPB A21D_RS16390 1dd71ca9c2c0364bd374c73b5e3c5097 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 28 1.7E-13 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS16390 1dd71ca9c2c0364bd374c73b5e3c5097 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 29 1.0E-15 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS07920 4c2a7387dfbce0acef2f2f096ccae988 254 Pfam PF00005 ABC transporter 2 112 9.7E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS07920 4c2a7387dfbce0acef2f2f096ccae988 254 Gene3D G3DSA:3.40.50.300 20 232 2.3E-42 T 28-03-2018 A21D_RS07920 4c2a7387dfbce0acef2f2f096ccae988 254 ProSitePatterns PS00211 ABC transporters family signature. 84 98 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS07920 4c2a7387dfbce0acef2f2f096ccae988 254 Pfam PF13732 Domain of unknown function (DUF4162) 165 252 5.1E-8 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 A21D_RS07920 4c2a7387dfbce0acef2f2f096ccae988 254 SUPERFAMILY SSF52540 1 174 1.65E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08040 34e0e1e84881c18c8e25bd3ecf59c2bb 288 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 9.0E-131 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS08040 34e0e1e84881c18c8e25bd3ecf59c2bb 288 Gene3D G3DSA:1.10.4100.10 62 262 4.5E-25 T 28-03-2018 A21D_RS08040 34e0e1e84881c18c8e25bd3ecf59c2bb 288 Pfam PF03313 Serine dehydratase alpha chain 15 274 7.5E-69 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A21D_RS01570 bbc86a2fdbcc62d189d834fa1c978f43 96 SUPERFAMILY SSF101386 17 95 7.85E-7 T 28-03-2018 A21D_RS01570 bbc86a2fdbcc62d189d834fa1c978f43 96 Gene3D G3DSA:1.10.287.1080 1 94 1.9E-9 T 28-03-2018 A21D_RS08880 0cf86d94ec34da06976b9c407f5f6232 131 Gene3D G3DSA:1.10.10.10 1 92 8.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08880 0cf86d94ec34da06976b9c407f5f6232 131 SUPERFAMILY SSF46785 8 82 6.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08880 0cf86d94ec34da06976b9c407f5f6232 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 1.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS08880 0cf86d94ec34da06976b9c407f5f6232 131 SMART SM00345 19 78 4.1E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS09830 1aa914b0a5ddf32d2e1ddff39955ec8c 320 Pfam PF12679 ABC-2 family transporter protein 7 317 9.6E-21 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS00050 109e693597560b9ed83e88cf0b68ed0d 100 Pfam PF05119 Phage terminase, small subunit 18 83 6.8E-6 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family A21D_RS02200 87907c87e4933e0afd9e1cb213f627a9 142 SUPERFAMILY SSF51730 10 116 1.18E-26 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS02200 87907c87e4933e0afd9e1cb213f627a9 142 Gene3D G3DSA:3.20.20.220 8 121 2.7E-22 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like A21D_RS02200 87907c87e4933e0afd9e1cb213f627a9 142 Pfam PF01619 Proline dehydrogenase 22 100 1.8E-11 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A21D_RS01030 24f5462eb3cd3b60acdb55ba09147d4e 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS01030 24f5462eb3cd3b60acdb55ba09147d4e 536 Gene3D G3DSA:3.90.350.10 230 497 2.9E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS01030 24f5462eb3cd3b60acdb55ba09147d4e 536 Pfam PF13751 Transposase DDE domain 393 518 4.5E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS03545 085d9fb451ace2f591bbe3ad21a96761 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 4.9E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS03545 085d9fb451ace2f591bbe3ad21a96761 333 Gene3D G3DSA:1.10.3720.10 2 321 1.2E-48 T 28-03-2018 A21D_RS03545 085d9fb451ace2f591bbe3ad21a96761 333 SUPERFAMILY SSF161098 90 159 5.45E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS03545 085d9fb451ace2f591bbe3ad21a96761 333 SUPERFAMILY SSF161098 196 319 5.45E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 Gene3D G3DSA:3.40.50.720 113 276 1.9E-27 T 28-03-2018 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 118 191 7.9E-14 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 2 274 3.5E-79 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 Gene3D G3DSA:3.40.50.10860 1 112 9.9E-40 T 28-03-2018 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 SUPERFAMILY SSF51735 100 273 1.1E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 SUPERFAMILY SSF53223 2 99 4.6E-30 T 28-03-2018 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 272 30.555 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A21D_RS15545 bd0f0c9a6ca4c0a928310c0606ccdc17 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 4 87 3.1E-27 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A21D_RS00805 934c04b468369485790c09e4c2b24788 302 Gene3D G3DSA:3.90.245.10 1 301 9.2E-81 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS00805 934c04b468369485790c09e4c2b24788 302 SUPERFAMILY SSF53590 5 299 7.06E-73 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS00805 934c04b468369485790c09e4c2b24788 302 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 292 1.6E-66 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 Gene3D G3DSA:3.20.20.140 93 377 2.4E-51 T 28-03-2018 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 416 7.9E-139 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 SUPERFAMILY SSF51338 377 419 7.09E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 SUPERFAMILY SSF51338 35 80 7.09E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 Pfam PF01979 Amidohydrolase family 76 417 1.5E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 Gene3D G3DSA:2.30.40.10 1 92 7.5E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 SUPERFAMILY SSF51556 79 378 4.54E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS12565 4a6be82d6aafd3ee37f201616726f25b 426 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 417 41.552 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 PIRSF PIRSF039004 3 372 2.0E-128 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 Gene3D G3DSA:2.30.40.10 4 55 2.2E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 Gene3D G3DSA:3.20.20.140 56 312 8.4E-38 T 28-03-2018 A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 SUPERFAMILY SSF51556 49 314 1.36E-62 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 5 362 2.3E-141 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 Pfam PF01979 Amidohydrolase family 45 329 1.0E-6 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 SUPERFAMILY SSF51338 4 49 2.41E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS02730 ea955540c646f0595fb1cfc3b21d2655 373 SUPERFAMILY SSF51338 315 363 2.41E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 SUPERFAMILY SSF52743 1 243 9.82E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 PRINTS PR00723 Subtilisin serine protease family (S8) signature 187 203 1.7E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 PRINTS PR00723 Subtilisin serine protease family (S8) signature 34 47 1.7E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 Pfam PF00082 Subtilase family 1 220 1.4E-37 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 1 12 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 Gene3D G3DSA:3.40.50.200 1 244 1.8E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS17200 e208c051e4b0f6ca3c7a694ec7a0d37e 249 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 38 48 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A21D_RS17015 5d74202fdd009e8ee22209052df3e07a 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS17015 5d74202fdd009e8ee22209052df3e07a 259 Gene3D G3DSA:1.10.12.10 217 259 9.1E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS17015 5d74202fdd009e8ee22209052df3e07a 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 258 2.2E-70 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS17015 5d74202fdd009e8ee22209052df3e07a 259 SUPERFAMILY SSF52096 4 258 1.04E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS17015 5d74202fdd009e8ee22209052df3e07a 259 Gene3D G3DSA:3.90.226.10 4 216 2.0E-75 T 28-03-2018 A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 Gene3D G3DSA:3.40.50.150 84 458 2.7E-56 T 28-03-2018 A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 390 421 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 442 452 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 Gene3D G3DSA:2.40.50.140 3 83 1.1E-10 T 28-03-2018 A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 SUPERFAMILY SSF53335 76 458 1.56E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 34 452 2.8E-104 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A21D_RS05000 9b732d50c6d4643ef44557f97e851333 463 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 98 458 4.3E-26 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A21D_RS14725 1353393e292732cdf423d96281d9dfe1 407 Gene3D G3DSA:3.40.1710.10 47 233 1.1E-19 T 28-03-2018 A21D_RS14725 1353393e292732cdf423d96281d9dfe1 407 Pfam PF12698 ABC-2 family transporter protein 27 398 2.9E-24 T 28-03-2018 A21D_RS15500 5112bb1793e797bf66f602c361693f12 126 Pfam PF03334 Na+/H+ antiporter subunit 17 98 5.5E-29 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 A21D_RS15500 5112bb1793e797bf66f602c361693f12 126 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 17 113 3.6E-33 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 A21D_RS05680 d94598e5125a385da0bcdae94c3e0164 281 PIRSF PIRSF035875 1 281 1.3E-75 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS05680 d94598e5125a385da0bcdae94c3e0164 281 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 7 265 2.8E-52 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS05680 d94598e5125a385da0bcdae94c3e0164 281 Pfam PF03631 Virulence factor BrkB 17 269 1.1E-65 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS12765 87434b90a502dfd3937fb25a229630bd 216 Gene3D G3DSA:3.40.1710.10 49 215 7.4E-12 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 SUPERFAMILY SSF52540 195 508 2.33E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Gene3D G3DSA:1.10.150.280 16 157 5.2E-7 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Gene3D G3DSA:1.10.150.20 165 219 0.026 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 11 748 27.745 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 15 743 5.5E-231 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Gene3D G3DSA:3.40.50.300 523 731 8.2E-31 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 SUPERFAMILY SSF52540 563 743 1.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 SUPERFAMILY SSF52540 460 526 1.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Pfam PF14520 Helix-hairpin-helix domain 107 154 7.4E-4 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Pfam PF13538 UvrD-like helicase C-terminal domain 671 718 4.7E-18 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Pfam PF14490 Helix-hairpin-helix containing domain 155 245 4.0E-28 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Pfam PF13604 AAA domain 337 543 4.4E-48 T 28-03-2018 A21D_RS15400 83be22f2bee8d717646de7e3c637eb72 773 Gene3D G3DSA:3.40.50.300 293 522 1.1E-31 T 28-03-2018 A21D_RS15565 2aa2a6a00b59ed2372ce634cda8f4492 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 24.212 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A21D_RS15565 2aa2a6a00b59ed2372ce634cda8f4492 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 4.2E-36 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A21D_RS15565 2aa2a6a00b59ed2372ce634cda8f4492 118 SUPERFAMILY SSF81301 2 113 1.06E-39 T 28-03-2018 A21D_RS15565 2aa2a6a00b59ed2372ce634cda8f4492 118 Gene3D G3DSA:3.30.460.10 1 118 1.4E-31 T 28-03-2018 A21D_RS15565 2aa2a6a00b59ed2372ce634cda8f4492 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 8.4E-26 T 28-03-2018 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 SUPERFAMILY SSF52540 360 607 1.7E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 Pfam PF00005 ABC transporter 387 536 1.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 SUPERFAMILY SSF90123 35 357 4.97E-75 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 SMART SM00382 396 582 7.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 Gene3D G3DSA:1.20.1560.10 29 357 1.1E-66 T 28-03-2018 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 Pfam PF00664 ABC transporter transmembrane region 51 319 2.9E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS18700 72b49034d02e2ba0ea2d9a0b154bd0a4 613 Gene3D G3DSA:3.40.50.300 358 611 7.9E-75 T 28-03-2018 A21D_RS17325 f4b122ac1402009f114351d511ed9e7b 100 Pfam PF05119 Phage terminase, small subunit 20 83 8.1E-6 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family A21D_RS10580 2f1798ae3faa7d2cebda81f7d2705030 493 ProSitePatterns PS01303 BCCT family of transporters signature. 310 319 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS10580 2f1798ae3faa7d2cebda81f7d2705030 493 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 488 5.8E-161 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS10580 2f1798ae3faa7d2cebda81f7d2705030 493 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 488 1.9E-186 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS10795 5f3e66e53e2028cf44de40dbac302d3c 307 Gene3D G3DSA:1.10.3720.10 30 294 5.8E-44 T 28-03-2018 A21D_RS10795 5f3e66e53e2028cf44de40dbac302d3c 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 71 1.0E-12 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A21D_RS10795 5f3e66e53e2028cf44de40dbac302d3c 307 SUPERFAMILY SSF161098 96 286 3.66E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10795 5f3e66e53e2028cf44de40dbac302d3c 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 304 6.4E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02785 8dcec8f4cd93383611777a873dc62fef 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 61 1.4E-21 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Pfam PF00149 Calcineurin-like phosphoesterase 638 874 1.5E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:2.40.50.90 414 567 5.2E-28 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 SUPERFAMILY SSF56300 636 947 2.68E-69 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:3.60.21.10 631 947 5.5E-67 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 SUPERFAMILY SSF50199 416 565 2.75E-26 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 ProSitePatterns PS00786 5'-nucleotidase signature 2. 718 729 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:2.60.40.1260 38 143 1.5E-9 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Pfam PF00746 LPXTG cell wall anchor motif 1226 1257 2.5E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:2.40.50.200 193 302 1.5E-14 T 28-03-2018 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Pfam PF00932 Lamin Tail Domain 39 143 2.3E-14 T 28-03-2018 IPR001322 Lamin Tail Domain A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Pfam PF02872 5'-nucleotidase, C-terminal domain 953 1088 1.1E-30 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 SMART SM00318 417 562 1.1E-21 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1227 1257 1.4E-4 T 28-03-2018 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:3.90.780.10 948 1137 9.5E-39 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 SUPERFAMILY SSF55816 945 1136 2.22E-41 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 PRINTS PR01607 Apyrase family signature 883 903 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 PRINTS PR01607 Apyrase family signature 857 880 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 PRINTS PR01607 Apyrase family signature 634 652 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 PRINTS PR01607 Apyrase family signature 1068 1087 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 PRINTS PR01607 Apyrase family signature 1000 1023 2.3E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Pfam PF00565 Staphylococcal nuclease homologue 443 561 1.0E-21 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A21D_RS03480 894992f5270b1b0d2bef6d25b4721ec6 1264 Gene3D G3DSA:3.40.10.10 570 624 0.0018 T 28-03-2018 IPR035451 Ada-like domain A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Gene3D G3DSA:3.40.50.1370 308 338 9.7E-6 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 SUPERFAMILY SSF53671 8 336 5.89E-103 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 335 82.873 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 333 8.1E-131 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Gene3D G3DSA:3.40.50.1370 1 151 2.1E-57 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 152 1.5E-47 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Gene3D G3DSA:3.40.50.1370 152 307 1.1E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 1.4E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 1.4E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 1.4E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 1.4E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 332 2.0E-56 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 1.9E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 232 242 1.9E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 1.9E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 1.9E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS02075 a649a4b300200e2e8f19fc1c48f2ff78 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 313 324 1.9E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 SUPERFAMILY SSF52402 2 171 2.65E-45 T 28-03-2018 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 Gene3D G3DSA:3.90.1260.10 159 353 2.7E-87 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 Gene3D G3DSA:3.40.50.620 4 158 9.6E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 397 54.794 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 Pfam PF00764 Arginosuccinate synthase 7 392 4.9E-177 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 SUPERFAMILY SSF69864 171 397 7.85E-94 T 28-03-2018 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 Gene3D G3DSA:1.20.5.470 363 396 4.7E-11 T 28-03-2018 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 394 6.0E-163 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS08680 f7178193bd8a3e40d931760820505dd9 421 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A21D_RS18445 e0d66a2bd86b366b38753e548bf2ea87 164 PIRSF PIRSF037732 1 163 1.3E-84 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP A21D_RS18445 e0d66a2bd86b366b38753e548bf2ea87 164 Hamap MF_00824 Uncharacterized N-acetyltransferase . 3 150 42.146 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP A21D_RS18445 e0d66a2bd86b366b38753e548bf2ea87 164 Pfam PF13508 Acetyltransferase (GNAT) domain 83 132 1.5E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS18445 e0d66a2bd86b366b38753e548bf2ea87 164 Gene3D G3DSA:3.40.630.30 1 162 1.8E-27 T 28-03-2018 A21D_RS18445 e0d66a2bd86b366b38753e548bf2ea87 164 SUPERFAMILY SSF55729 30 146 9.97E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS15990 423dc709f85e0eb360f739a136003b7b 259 Pfam PF11079 Bacterial protein YqhG of unknown function 1 254 1.3E-100 T 28-03-2018 IPR024562 Uncharacterised protein family YqhG A21D_RS15990 423dc709f85e0eb360f739a136003b7b 259 ProDom PD123329 YQHG BH2818 1 254 1.0E-85 T 28-03-2018 IPR024562 Uncharacterised protein family YqhG A21D_RS02025 49871491cf76d14d5809c1781439a20d 577 Pfam PF07075 Protein of unknown function (DUF1343) 21 377 7.2E-125 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 A21D_RS02025 49871491cf76d14d5809c1781439a20d 577 Gene3D G3DSA:2.60.40.1080 389 472 7.4E-4 T 28-03-2018 A21D_RS04450 1ca5a45fa8ca974747714a7b24b4f3ca 275 SUPERFAMILY SSF117143 100 236 7.45E-10 T 28-03-2018 A21D_RS04450 1ca5a45fa8ca974747714a7b24b4f3ca 275 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 195 274 1.9E-17 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A21D_RS04450 1ca5a45fa8ca974747714a7b24b4f3ca 275 Pfam PF00460 Flagella basal body rod protein 8 35 1.5E-7 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS04450 1ca5a45fa8ca974747714a7b24b4f3ca 275 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 146 3.2E-24 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A21D_RS04150 1d18fb2665e87f55c0ee10eddf652003 344 SUPERFAMILY SSF74650 11 340 1.07E-93 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A21D_RS04150 1d18fb2665e87f55c0ee10eddf652003 344 Pfam PF01263 Aldose 1-epimerase 16 339 1.9E-73 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A21D_RS04150 1d18fb2665e87f55c0ee10eddf652003 344 Gene3D G3DSA:2.70.98.10 1 344 6.9E-94 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A21D_RS04150 1d18fb2665e87f55c0ee10eddf652003 344 PIRSF PIRSF005096 1 343 1.0E-111 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Pfam PF02817 e3 binding domain 127 161 2.5E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 189 415 6.0E-68 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Gene3D G3DSA:3.30.559.10 176 416 7.6E-67 T 28-03-2018 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Gene3D G3DSA:2.40.50.100 5 79 5.1E-15 T 28-03-2018 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 SUPERFAMILY SSF52777 180 416 5.78E-65 T 28-03-2018 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 SUPERFAMILY SSF47005 121 164 7.46E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 SUPERFAMILY SSF51230 1 94 5.37E-23 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Gene3D G3DSA:4.10.320.10 117 175 1.7E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A21D_RS19530 f4706424c5ce3e9898758d3260d4680b 416 Pfam PF00364 Biotin-requiring enzyme 5 74 5.8E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS09475 47918e2dc2d6b228e1d23670fe86c444 95 Gene3D G3DSA:3.40.50.2300 1 94 8.1E-21 T 28-03-2018 A21D_RS09475 47918e2dc2d6b228e1d23670fe86c444 95 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 70 3.5E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS09475 47918e2dc2d6b228e1d23670fe86c444 95 SUPERFAMILY SSF52794 3 93 1.1E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 SUPERFAMILY SSF53067 7 127 4.79E-32 T 28-03-2018 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.1E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 310 1.6E-114 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 Gene3D G3DSA:3.30.420.40 5 148 1.0E-42 T 28-03-2018 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 317 3.5E-138 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 Gene3D G3DSA:3.30.420.40 149 293 1.5E-20 T 28-03-2018 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 335 63.773 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 SUPERFAMILY SSF53067 107 312 1.55E-45 T 28-03-2018 A21D_RS10190 ea09e46a9cec8aec91852421814270f5 336 Pfam PF00814 Glycoprotease family 27 310 1.1E-107 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A21D_RS04110 e8a70f759e0ce80e985f29f3572f2c3c 392 SUPERFAMILY SSF53697 16 380 2.02E-44 T 28-03-2018 A21D_RS04110 e8a70f759e0ce80e985f29f3572f2c3c 392 Gene3D G3DSA:3.40.50.10490 195 383 4.0E-21 T 28-03-2018 A21D_RS04110 e8a70f759e0ce80e985f29f3572f2c3c 392 Gene3D G3DSA:3.40.50.10490 1 193 3.6E-24 T 28-03-2018 A21D_RS04110 e8a70f759e0ce80e985f29f3572f2c3c 392 Pfam PF01380 SIS domain 228 340 7.2E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS04110 e8a70f759e0ce80e985f29f3572f2c3c 392 Pfam PF01380 SIS domain 54 192 1.0E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS00685 1b524fdb1fe896d6d12f32e27fbc12f7 179 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 7 179 1.5E-66 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A21D_RS00685 1b524fdb1fe896d6d12f32e27fbc12f7 179 Gene3D G3DSA:3.20.20.400 3 179 2.9E-69 T 28-03-2018 A21D_RS00685 1b524fdb1fe896d6d12f32e27fbc12f7 179 SUPERFAMILY SSF110391 7 179 5.1E-61 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A21D_RS00685 1b524fdb1fe896d6d12f32e27fbc12f7 179 PIRSF PIRSF016897 3 179 6.1E-67 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A21D_RS10750 976fd3f0f95156fc5177ced085a9c5aa 155 Gene3D G3DSA:2.60.40.790 9 153 2.9E-36 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS10750 976fd3f0f95156fc5177ced085a9c5aa 155 SUPERFAMILY SSF49764 19 153 1.33E-39 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS10750 976fd3f0f95156fc5177ced085a9c5aa 155 Pfam PF00011 Hsp20/alpha crystallin family 52 152 8.0E-28 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Gene3D G3DSA:2.40.110.10 128 219 9.3E-29 T 28-03-2018 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 SUPERFAMILY SSF47203 222 377 9.5E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 114 3.1E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 212 4.6E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 372 5.9E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 SUPERFAMILY SSF56645 2 235 4.45E-54 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 120 132 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Gene3D G3DSA:1.20.140.10 220 381 4.2E-46 T 28-03-2018 A21D_RS11070 ec0a548d62e6da872192b58ecf29cae2 393 Gene3D G3DSA:1.10.540.10 1 127 1.5E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS19130 3c18be58b0fb87494191e3fa50459d10 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 260 2.0E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS19130 3c18be58b0fb87494191e3fa50459d10 272 Gene3D G3DSA:1.10.3720.10 8 268 2.2E-33 T 28-03-2018 A21D_RS19130 3c18be58b0fb87494191e3fa50459d10 272 SUPERFAMILY SSF161098 8 272 4.02E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 720 0.0 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Gene3D G3DSA:1.20.1220.12 587 726 1.5E-45 T 28-03-2018 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Hamap MF_00641 Malate synthase G [glcB]. 1 726 372.883 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Pfam PF01274 Malate synthase 17 695 3.2E-174 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Gene3D G3DSA:1.10.1860.10 1 86 3.2E-30 T 28-03-2018 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 SUPERFAMILY SSF51645 3 719 7.32E-296 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Gene3D G3DSA:3.20.20.360 87 215 1.1E-21 T 28-03-2018 A21D_RS11190 31c5dfd0744d0218d68e1de55214870c 726 Gene3D G3DSA:3.20.20.360 218 586 3.5E-101 T 28-03-2018 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 SUPERFAMILY SSF102114 21 220 3.66E-27 T 28-03-2018 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 Pfam PF13353 4Fe-4S single cluster domain 14 134 7.3E-21 T 28-03-2018 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 Pfam PF04055 Radical SAM superfamily 22 184 4.3E-26 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 Gene3D G3DSA:3.80.30.10 65 241 1.9E-39 T 28-03-2018 A21D_RS04745 1fafcc136050894bc2c67f07a43c865f 244 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 4 238 5.2E-95 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 A21D_RS00500 dae7f423c42fb948db7b07c244bb3171 333 Pfam PF09084 NMT1/THI5 like 47 260 1.8E-76 T 28-03-2018 IPR015168 SsuA/THI5-like A21D_RS00500 dae7f423c42fb948db7b07c244bb3171 333 Gene3D G3DSA:3.40.190.10 34 140 2.9E-20 T 28-03-2018 A21D_RS00500 dae7f423c42fb948db7b07c244bb3171 333 Gene3D G3DSA:3.40.190.10 142 333 1.5E-26 T 28-03-2018 A21D_RS00500 dae7f423c42fb948db7b07c244bb3171 333 SUPERFAMILY SSF53850 41 320 2.67E-53 T 28-03-2018 A21D_RS03235 345b9ddd20d68e9f1783af9064f42749 265 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 252 5.8E-86 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A21D_RS03235 345b9ddd20d68e9f1783af9064f42749 265 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 47 65 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A21D_RS03235 345b9ddd20d68e9f1783af9064f42749 265 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 254 32.419 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A21D_RS03235 345b9ddd20d68e9f1783af9064f42749 265 SUPERFAMILY SSF51366 19 253 3.39E-79 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A21D_RS03235 345b9ddd20d68e9f1783af9064f42749 265 Gene3D G3DSA:3.20.20.70 3 255 2.9E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS13155 0713c23c460c9309be0f01b176e6a970 248 SMART SM00382 29 214 6.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13155 0713c23c460c9309be0f01b176e6a970 248 SUPERFAMILY SSF52540 4 231 3.52E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13155 0713c23c460c9309be0f01b176e6a970 248 Pfam PF00005 ABC transporter 20 163 6.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13155 0713c23c460c9309be0f01b176e6a970 248 Gene3D G3DSA:3.40.50.300 1 247 1.1E-56 T 28-03-2018 A21D_RS08520 d704ee7d080028a7c9fb9ee5de468b0a 141 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 20 128 1.8E-15 T 28-03-2018 A21D_RS08520 d704ee7d080028a7c9fb9ee5de468b0a 141 SUPERFAMILY SSF50475 7 131 9.23E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A21D_RS08520 d704ee7d080028a7c9fb9ee5de468b0a 141 Gene3D G3DSA:2.30.110.10 2 141 2.4E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A21D_RS18730 e0ed5f4e3539374727a2665ba26bf67d 146 Pfam PF00571 CBS domain 86 139 6.0E-4 T 28-03-2018 IPR000644 CBS domain A21D_RS18730 e0ed5f4e3539374727a2665ba26bf67d 146 Pfam PF00571 CBS domain 16 71 1.3E-5 T 28-03-2018 IPR000644 CBS domain A21D_RS18730 e0ed5f4e3539374727a2665ba26bf67d 146 Gene3D G3DSA:3.10.580.10 3 146 1.5E-21 T 28-03-2018 A21D_RS18730 e0ed5f4e3539374727a2665ba26bf67d 146 SUPERFAMILY SSF54631 12 140 7.78E-29 T 28-03-2018 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 Pfam PF01678 Diaminopimelate epimerase 160 275 5.9E-30 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 Pfam PF01678 Diaminopimelate epimerase 5 128 4.3E-30 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 Gene3D G3DSA:3.10.310.10 1 129 4.2E-44 T 28-03-2018 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 283 36.449 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 281 1.4E-91 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 SUPERFAMILY SSF54506 3 279 1.57E-48 T 28-03-2018 A21D_RS13930 bbc8b47203b5f81c190596fe9d8f572f 289 Gene3D G3DSA:3.10.310.10 130 270 1.2E-44 T 28-03-2018 A21D_RS08570 0926154b5173d85e661964e8841a4064 284 SUPERFAMILY SSF56784 2 281 4.14E-64 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08570 0926154b5173d85e661964e8841a4064 284 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 277 1.4E-58 T 28-03-2018 IPR000150 Cof family GO:0016787 A21D_RS08570 0926154b5173d85e661964e8841a4064 284 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 28-03-2018 A21D_RS08570 0926154b5173d85e661964e8841a4064 284 ProSitePatterns PS01229 Hypothetical cof family signature 2. 231 253 - T 28-03-2018 A21D_RS08570 0926154b5173d85e661964e8841a4064 284 Gene3D G3DSA:3.40.50.1000 1 284 2.5E-37 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08570 0926154b5173d85e661964e8841a4064 284 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 277 6.9E-62 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08570 0926154b5173d85e661964e8841a4064 284 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 250 1.8E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS10700 ef26cf86600dfa3c805c29c9af7fceff 505 Pfam PF03806 AbgT putative transporter family 12 502 4.5E-186 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 A21D_RS03085 3e3017151b38137cb3d087b7257750da 317 SUPERFAMILY SSF81345 3 312 2.35E-68 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS03085 3e3017151b38137cb3d087b7257750da 317 Gene3D G3DSA:1.10.3470.10 1 314 1.1E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS03085 3e3017151b38137cb3d087b7257750da 317 Pfam PF01032 FecCD transport family 9 311 4.3E-68 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 SUPERFAMILY SSF100950 1 238 4.19E-92 T 28-03-2018 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 Gene3D G3DSA:3.40.50.1360 1 241 5.7E-76 T 28-03-2018 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 239 8.6E-96 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 230 2.7E-22 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A21D_RS00930 f85a60d629b253137926031c425afc5b 241 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 42.583 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 Gene3D G3DSA:3.30.565.10 290 442 5.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 SUPERFAMILY SSF47384 214 294 7.65E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 438 6.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 403 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 Gene3D G3DSA:1.10.287.130 219 289 2.6E-16 T 28-03-2018 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 SUPERFAMILY SSF55874 284 440 2.62E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 294 6.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 SMART SM00387 340 443 2.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS03995 452199ae87e9d7438733f2c566b37c05 443 SMART SM00388 229 295 1.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 175 1.1E-54 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 175 2.0E-51 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 21.92 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 SUPERFAMILY SSF47928 2 106 9.02E-27 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.6E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.6E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.6E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.6E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.6E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS04550 698978b76ec37ae9e8abd4c97398b63f 181 Gene3D G3DSA:1.10.520.20 2 106 9.5E-28 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A21D_RS01010 f9af80db7e9bb0d83ea9b311a20a88a7 652 Pfam PF00884 Sulfatase 245 539 6.3E-32 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A21D_RS01010 f9af80db7e9bb0d83ea9b311a20a88a7 652 PIRSF PIRSF005091 1 624 5.4E-188 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like A21D_RS01010 f9af80db7e9bb0d83ea9b311a20a88a7 652 SUPERFAMILY SSF53649 243 624 8.18E-70 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS01010 f9af80db7e9bb0d83ea9b311a20a88a7 652 Gene3D G3DSA:3.40.720.10 238 549 1.5E-39 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS18775 0c2a68420d02ffb939c704708e0865a9 387 Pfam PF00155 Aminotransferase class I and II 29 377 1.2E-61 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A21D_RS18775 0c2a68420d02ffb939c704708e0865a9 387 Gene3D G3DSA:3.40.640.10 43 293 9.2E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS18775 0c2a68420d02ffb939c704708e0865a9 387 Gene3D G3DSA:3.90.1150.10 294 385 5.8E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS18775 0c2a68420d02ffb939c704708e0865a9 387 SUPERFAMILY SSF53383 4 383 1.34E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS18775 0c2a68420d02ffb939c704708e0865a9 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A21D_RS12085 0779d3ac59fdf37b6c70acfe1affe2b0 84 SMART SM00899 5 78 1.1E-18 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A21D_RS12085 0779d3ac59fdf37b6c70acfe1affe2b0 84 Pfam PF04023 FeoA domain 7 75 1.4E-17 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A21D_RS12085 0779d3ac59fdf37b6c70acfe1affe2b0 84 SUPERFAMILY SSF50037 9 79 2.01E-18 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal A21D_RS12085 0779d3ac59fdf37b6c70acfe1affe2b0 84 Gene3D G3DSA:2.30.30.90 8 83 8.1E-21 T 28-03-2018 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 Pfam PF02833 DHHA2 domain 182 306 4.8E-19 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 Pfam PF01368 DHH family 3 145 2.4E-31 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 SUPERFAMILY SSF64182 3 305 1.14E-75 T 28-03-2018 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 Gene3D G3DSA:3.90.1640.10 1 187 2.4E-66 T 28-03-2018 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 SMART SM01131 180 307 2.1E-49 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS01590 09848de5ada8ea8a8b720df51ad4fb2b 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 43.13 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS16530 7b3319cc1cd9e246097155002abba665 194 Gene3D G3DSA:3.40.1130.10 2 193 6.3E-45 T 28-03-2018 A21D_RS16530 7b3319cc1cd9e246097155002abba665 194 SMART SM00563 35 147 5.2E-36 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS16530 7b3319cc1cd9e246097155002abba665 194 Pfam PF01553 Acyltransferase 20 144 3.0E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A21D_RS16530 7b3319cc1cd9e246097155002abba665 194 SUPERFAMILY SSF69593 3 191 2.48E-55 T 28-03-2018 A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 Pfam PF06826 Predicted Permease Membrane Region 16 168 4.0E-36 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 Pfam PF06826 Predicted Permease Membrane Region 360 528 6.8E-33 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 Gene3D G3DSA:3.30.70.1450 274 351 7.9E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 SUPERFAMILY SSF116726 270 346 3.4E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 365 516 5.9E-31 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 155 4.8E-24 T 28-03-2018 IPR006512 YidE/YbjL duplication A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 Pfam PF02080 TrkA-C domain 280 345 1.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 Gene3D G3DSA:3.30.70.1450 187 268 2.7E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12375 ac82b5ed0141f63b833e12c7f6abb429 532 SUPERFAMILY SSF116726 192 262 8.11E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS18540 4d0ddac8a6472023a483f1a55e8121c7 207 SUPERFAMILY SSF81452 19 204 4.84E-57 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18540 4d0ddac8a6472023a483f1a55e8121c7 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 3.7E-21 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18540 4d0ddac8a6472023a483f1a55e8121c7 207 Gene3D G3DSA:1.20.120.80 21 206 6.6E-51 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS12705 a716966a8160b684fb209ea7bc32db95 328 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 318 2.4E-60 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A21D_RS12705 a716966a8160b684fb209ea7bc32db95 328 SUPERFAMILY SSF51735 1 327 7.44E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12705 a716966a8160b684fb209ea7bc32db95 328 PIRSF PIRSF001439 1 328 3.8E-74 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A21D_RS12705 a716966a8160b684fb209ea7bc32db95 328 Gene3D G3DSA:3.30.1780.10 1 137 4.8E-36 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A21D_RS12705 a716966a8160b684fb209ea7bc32db95 328 Gene3D G3DSA:3.40.50.720 138 300 6.4E-32 T 28-03-2018 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 3.3E-232 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 Gene3D G3DSA:3.40.50.720 1 180 1.9E-36 T 28-03-2018 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 168 3.2E-53 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 254 266 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 Gene3D G3DSA:1.20.5.320 438 469 3.5E-19 T 28-03-2018 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 67 96 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 120 145 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 250 277 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 358 380 1.6E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 PIRSF PIRSF000109 1 469 1.7E-246 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 6.0E-138 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 SUPERFAMILY SSF51735 4 177 3.1E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 SUPERFAMILY SSF48179 177 468 9.72E-135 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 SMART SM01350 179 469 7.6E-233 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A21D_RS04310 575f12224eeccb708ef4c35dfc5297d2 469 Gene3D G3DSA:1.10.1040.10 181 436 2.5E-118 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS04430 0bedbb0c72a94dbfbe323d98853aa071 171 Pfam PF06338 ComK protein 9 151 2.5E-33 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 A21D_RS16455 a589c6524925e38233c0f2e9fe9b5e4c 176 Pfam PF07155 ECF-type riboflavin transporter, S component 2 153 4.7E-7 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 Gene3D G3DSA:1.10.10.10 1 91 5.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.4E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.4E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.4E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 Gene3D G3DSA:3.40.190.10 178 267 3.9E-23 T 28-03-2018 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 SUPERFAMILY SSF53850 90 292 1.96E-41 T 28-03-2018 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 Gene3D G3DSA:3.40.190.10 92 177 6.0E-19 T 28-03-2018 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 Pfam PF03466 LysR substrate binding domain 89 290 2.7E-46 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.1E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS11185 2fb2beff16f8edcf581e735ece877d76 294 SUPERFAMILY SSF46785 1 83 7.14E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 SUPERFAMILY SSF53850 90 293 2.39E-40 T 28-03-2018 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 Gene3D G3DSA:1.10.10.10 1 83 3.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 SUPERFAMILY SSF46785 1 84 2.72E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 Gene3D G3DSA:3.40.190.10 177 265 1.4E-25 T 28-03-2018 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 Gene3D G3DSA:3.40.190.10 88 176 4.1E-22 T 28-03-2018 A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 Pfam PF03466 LysR substrate binding domain 89 290 4.4E-44 T 28-03-2018 IPR005119 LysR, substrate-binding A21D_RS09215 77a3212b65533c7a26a34c2918ffecdd 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 SUPERFAMILY SSF53613 5 253 2.46E-58 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 6 249 8.8E-80 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 Pfam PF02110 Hydroxyethylthiazole kinase family 6 249 7.1E-79 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 8 257 29.869 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 58 66 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 14 21 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 158 175 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 27 48 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 115 129 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 84 101 3.7E-37 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 PIRSF PIRSF000513 1 257 2.3E-88 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS03575 ee6fae12c0f9ea1ac94c495c699048f9 257 Gene3D G3DSA:3.40.1190.20 1 254 3.3E-55 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS05695 9ef6a3169461f0401350beb4888e48d2 637 Gene3D G3DSA:3.40.50.410 435 621 1.1E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS05695 9ef6a3169461f0401350beb4888e48d2 637 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 432 560 6.1E-5 T 28-03-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A21D_RS05695 9ef6a3169461f0401350beb4888e48d2 637 SMART SM00327 442 633 1.4E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS05695 9ef6a3169461f0401350beb4888e48d2 637 SUPERFAMILY SSF53300 444 632 2.14E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 87 158 1.9E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.018 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 Gene3D G3DSA:3.10.50.30 79 158 2.5E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 PIRSF PIRSF006092 1 158 5.3E-52 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 Gene3D G3DSA:1.10.287.180 6 78 6.9E-32 T 28-03-2018 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 6.0E-31 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 SUPERFAMILY SSF46557 6 79 1.2E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 SUPERFAMILY SSF54534 83 157 1.44E-20 T 28-03-2018 A21D_RS15455 e8f9846b51f381c70cf5212c17f2ff05 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 6.6E-56 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 Gene3D G3DSA:3.40.50.1100 145 333 1.3E-47 T 28-03-2018 A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 316 4.6E-74 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 TIGRFAM TIGR00260 thrC: threonine synthase 9 322 5.4E-98 T 28-03-2018 IPR004450 Threonine synthase-like A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 SUPERFAMILY SSF53686 6 349 8.38E-101 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 Gene3D G3DSA:3.40.50.1100 38 144 2.7E-28 T 28-03-2018 A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 PIRSF PIRSF038945 1 349 1.3E-154 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A21D_RS03655 a6a4bc5c469b61057d70c449a5ee7922 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 SUPERFAMILY SSF46955 8 115 8.42E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 Gene3D G3DSA:1.10.1660.10 8 66 8.2E-18 T 28-03-2018 A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 Gene3D G3DSA:1.10.1660.10 67 124 1.6E-5 T 28-03-2018 A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 SUPERFAMILY SSF55136 133 253 3.49E-8 T 28-03-2018 A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 Gene3D G3DSA:3.20.80.10 125 282 8.3E-15 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 SMART SM00422 9 79 1.7E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS05975 aa474f988516ce0d1d3db3b6f6e6933e 282 Pfam PF13411 MerR HTH family regulatory protein 9 77 4.2E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 SUPERFAMILY SSF52172 5 133 5.69E-30 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 Gene3D G3DSA:2.20.25.10 204 241 9.6E-11 T 28-03-2018 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 Gene3D G3DSA:3.40.50.2300 4 136 2.2E-28 T 28-03-2018 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 SMART SM00850 143 241 2.3E-35 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 Pfam PF00072 Response regulator receiver domain 8 116 7.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 Gene3D G3DSA:2.40.50.40 137 203 7.8E-18 T 28-03-2018 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 SMART SM00448 5 116 2.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01260 2736d67d40ee7b6879edf39f985cb30d 242 Pfam PF04397 LytTr DNA-binding domain 144 240 3.9E-28 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS07550 6f8d9f854c01f4710eb150f9e6502bf6 228 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 12 169 9.5E-41 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A21D_RS07550 6f8d9f854c01f4710eb150f9e6502bf6 228 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 70 2.6E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A21D_RS07550 6f8d9f854c01f4710eb150f9e6502bf6 228 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A21D_RS11360 da9364497feb0c57276a5fc39440f31b 132 SUPERFAMILY SSF75169 5 132 7.4E-23 T 28-03-2018 IPR027396 DsrEFH-like A21D_RS11360 da9364497feb0c57276a5fc39440f31b 132 Gene3D G3DSA:3.40.1260.10 1 131 1.5E-37 T 28-03-2018 A21D_RS11360 da9364497feb0c57276a5fc39440f31b 132 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 55 4.3E-11 T 28-03-2018 IPR032836 DsrE2-like family A21D_RS11360 da9364497feb0c57276a5fc39440f31b 132 Pfam PF13686 DsrE/DsrF/DrsH-like family 63 130 1.3E-20 T 28-03-2018 IPR032836 DsrE2-like family A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 SUPERFAMILY SSF53187 3 199 1.08E-84 T 28-03-2018 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 SUPERFAMILY SSF53187 300 386 1.08E-84 T 28-03-2018 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 SUPERFAMILY SSF55031 183 301 1.96E-30 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 375 1.3E-114 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 PIRSF PIRSF005962 1 389 4.0E-127 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 Gene3D G3DSA:3.40.630.10 241 389 6.9E-20 T 28-03-2018 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 Gene3D G3DSA:3.40.630.10 2 218 3.1E-51 T 28-03-2018 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 Pfam PF01546 Peptidase family M20/M25/M40 74 380 8.2E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS13165 9c97a68f5ea2a605b2fd4b37ef9c11bd 389 Pfam PF07687 Peptidase dimerisation domain 184 277 1.7E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 218 380 3.6E-32 T 28-03-2018 IPR000160 GGDEF domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 376 7.5E-42 T 28-03-2018 IPR000160 GGDEF domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 SMART SM00267 210 381 3.2E-48 T 28-03-2018 IPR000160 GGDEF domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Gene3D G3DSA:3.20.20.450 389 648 3.5E-98 T 28-03-2018 IPR001633 EAL domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Gene3D G3DSA:3.30.70.270 219 388 4.4E-49 T 28-03-2018 A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Gene3D G3DSA:3.30.450.20 10 103 8.3E-5 T 28-03-2018 A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 SUPERFAMILY SSF141868 396 642 2.48E-88 T 28-03-2018 IPR001633 EAL domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 SMART SM00052 391 635 3.3E-116 T 28-03-2018 IPR001633 EAL domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Gene3D G3DSA:3.30.450.20 119 218 0.018 T 28-03-2018 A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 Pfam PF00563 EAL domain 397 629 9.5E-74 T 28-03-2018 IPR001633 EAL domain A21D_RS18805 928c1ce036124de75ffa4435f2c5361d 648 SUPERFAMILY SSF55073 226 382 4.32E-41 T 28-03-2018 IPR029787 Nucleotide cyclase A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Gene3D G3DSA:2.60.40.1760 24 238 3.9E-54 T 28-03-2018 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Gene3D G3DSA:2.60.40.1180 675 781 1.2E-11 T 28-03-2018 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 SUPERFAMILY SSF51445 241 588 2.8E-98 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 403 410 - T 28-03-2018 IPR030458 Glycosyl hydrolases family 31, active site A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 SUPERFAMILY SSF51011 590 669 2.23E-23 T 28-03-2018 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Pfam PF13802 Galactose mutarotase-like 147 213 1.4E-27 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Pfam PF16338 Domain of unknown function (DUF4968) 34 124 9.1E-16 T 28-03-2018 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Gene3D G3DSA:2.60.40.1180 610 670 4.5E-25 T 28-03-2018 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Pfam PF01055 Glycosyl hydrolases family 31 233 672 5.0E-161 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 SUPERFAMILY SSF74650 25 240 2.54E-52 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Pfam PF17137 Domain of unknown function (DUF5110) 691 760 2.1E-13 T 28-03-2018 IPR033403 Domain of unknown function DUF5110 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 Gene3D G3DSA:3.20.20.80 239 609 6.7E-161 T 28-03-2018 A21D_RS01095 0ac97c4159b873ab7a8ae033fabe72b9 782 ProSitePatterns PS00707 Glycosyl hydrolases family 31 signature 2. 511 541 - T 28-03-2018 IPR030459 Glycosyl hydrolases family 31, conserved site A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 19 40 8.2E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 8.2E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 8.2E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 76 95 8.2E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 Pfam PF01311 Bacterial export proteins, family 1 11 243 5.7E-73 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A21D_RS17860 454d0c216e2a5407cc3d44d71251d2c7 259 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 12 253 2.9E-70 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 282 372 3.8E-12 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 Gene3D G3DSA:3.40.710.10 23 281 2.9E-48 T 28-03-2018 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 262 1.2E-84 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 SUPERFAMILY SSF69189 274 371 9.61E-15 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 SUPERFAMILY SSF56601 1 282 1.93E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 145 158 5.3E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 5.3E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 5.3E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 Gene3D G3DSA:2.60.410.10 282 373 1.4E-15 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS16335 de1c722e9cb3a3783dcbe28584988b7d 391 SMART SM00936 282 373 7.8E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 Gene3D G3DSA:1.10.580.10 1 257 5.2E-75 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 Pfam PF00285 Citrate synthase, C-terminal domain 10 360 7.3E-111 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PIRSF PIRSF001369 1 368 5.2E-134 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 Gene3D G3DSA:1.10.580.10 302 357 1.3E-6 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 SUPERFAMILY SSF48256 6 366 2.09E-118 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 ProSitePatterns PS00480 Citrate synthase signature. 259 272 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 330 344 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 177 192 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 128 141 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 199 227 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 252 272 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11225 936408154cabc08ddae4c0b9be24de47 368 PRINTS PR00143 Citrate synthase signature 310 326 5.4E-32 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS16890 2943e42c85286a6885aa9bb83e3a725d 187 Gene3D G3DSA:1.10.10.60 1 48 3.9E-11 T 28-03-2018 A21D_RS16890 2943e42c85286a6885aa9bb83e3a725d 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS16890 2943e42c85286a6885aa9bb83e3a725d 187 Gene3D G3DSA:1.10.357.10 49 184 2.2E-10 T 28-03-2018 A21D_RS16890 2943e42c85286a6885aa9bb83e3a725d 187 SUPERFAMILY SSF48498 74 183 4.19E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A21D_RS16890 2943e42c85286a6885aa9bb83e3a725d 187 SUPERFAMILY SSF46689 2 63 2.46E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS17565 6228f9beb51f261479e57e63c38d2fd5 264 PIRSF PIRSF004789 1 264 4.3E-108 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A21D_RS17565 6228f9beb51f261479e57e63c38d2fd5 264 Gene3D G3DSA:3.60.21.10 1 264 2.0E-54 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS17565 6228f9beb51f261479e57e63c38d2fd5 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 4.3E-112 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A21D_RS17565 6228f9beb51f261479e57e63c38d2fd5 264 SUPERFAMILY SSF56300 1 257 1.55E-90 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS17565 6228f9beb51f261479e57e63c38d2fd5 264 Pfam PF13277 YmdB-like protein 4 255 5.6E-111 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A21D_RS09715 597c7f49a96ceb3d6cbaf94c2f62a6e4 716 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 28 706 1.3E-203 T 28-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein A21D_RS09715 597c7f49a96ceb3d6cbaf94c2f62a6e4 716 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 122 390 1.4E-60 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A21D_RS09715 597c7f49a96ceb3d6cbaf94c2f62a6e4 716 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 439 633 6.4E-21 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 SUPERFAMILY SSF48452 23 122 2.07E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 Gene3D G3DSA:1.25.40.10 269 329 3.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 Gene3D G3DSA:1.25.40.10 152 268 5.1E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 Gene3D G3DSA:1.25.40.10 6 151 1.2E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 SUPERFAMILY SSF48452 26 87 4.55E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS00675 b27c5cfc44b73beb071dac51c62f1fef 332 SUPERFAMILY SSF48452 150 321 4.55E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 3.9E-86 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 Gene3D G3DSA:3.30.1330.90 20 141 1.1E-25 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 PIRSF PIRSF036692 1 220 1.3E-104 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 Pfam PF03315 Serine dehydratase beta chain 5 86 1.8E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 Gene3D G3DSA:3.30.70.260 142 217 1.7E-17 T 28-03-2018 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 SUPERFAMILY SSF143548 19 137 5.89E-31 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 SUPERFAMILY SSF55021 137 215 3.66E-17 T 28-03-2018 A21D_RS18135 fdb9d8c1388bcc9294787eccef5939ac 220 Pfam PF01842 ACT domain 150 210 1.6E-11 T 28-03-2018 IPR002912 ACT domain A21D_RS11435 142f3baf5ae35237f5f8695d8f562657 348 Gene3D G3DSA:3.60.60.10 100 331 1.3E-32 T 28-03-2018 A21D_RS11435 142f3baf5ae35237f5f8695d8f562657 348 SUPERFAMILY SSF56235 110 326 2.24E-13 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS11435 142f3baf5ae35237f5f8695d8f562657 348 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 105 311 1.1E-65 T 28-03-2018 IPR005079 Peptidase C45 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 SUPERFAMILY SSF46689 15 88 3.99E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 Gene3D G3DSA:1.10.357.10 76 208 5.6E-9 T 28-03-2018 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 Gene3D G3DSA:1.10.10.60 11 42 2.5E-12 T 28-03-2018 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04710 147fe31e2be84b6812d2d53dd289644b 208 Gene3D G3DSA:1.10.260.40 43 75 4.1E-12 T 28-03-2018 A21D_RS13820 a77f049bdb8d56ad69a9bfd6ed7c42db 425 Pfam PF03611 PTS system sugar-specific permease component 10 399 3.6E-100 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 SUPERFAMILY SSF53067 209 380 1.02E-28 T 28-03-2018 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Gene3D G3DSA:3.30.420.40 1 193 1.4E-24 T 28-03-2018 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 SMART SM00842 5 202 1.8E-39 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 SUPERFAMILY SSF53067 4 199 4.19E-22 T 28-03-2018 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Pfam PF11104 Type IV pilus assembly protein PilM; 8 344 1.6E-12 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Gene3D G3DSA:3.10.20.30 478 531 0.27 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Gene3D G3DSA:3.10.20.30 532 598 0.003 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Gene3D G3DSA:3.30.420.40 209 348 4.8E-18 T 28-03-2018 A21D_RS14335 3979dc79e250a434021aae7a40885187 709 Gene3D G3DSA:3.10.20.30 659 707 0.11 T 28-03-2018 IPR012675 Beta-grasp domain A21D_RS17505 4555cfc31423e2ba96d6fd2642255900 412 Gene3D G3DSA:3.40.640.10 49 262 1.4E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS17505 4555cfc31423e2ba96d6fd2642255900 412 SUPERFAMILY SSF53383 45 389 2.51E-44 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS17505 4555cfc31423e2ba96d6fd2642255900 412 Pfam PF06838 Methionine gamma-lyase 5 405 7.2E-206 T 28-03-2018 IPR009651 Putative methionine gamma-lyase A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 PRINTS PR01950 LanC-like protein superfamily signature 814 827 1.1E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 PRINTS PR01950 LanC-like protein superfamily signature 563 581 1.1E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 PRINTS PR01950 LanC-like protein superfamily signature 661 676 1.1E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 PRINTS PR01950 LanC-like protein superfamily signature 720 736 1.1E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 SMART SM01260 560 895 9.0E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 SUPERFAMILY SSF158745 544 878 3.53E-39 T 28-03-2018 A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 20 878 1.6E-134 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 PIRSF PIRSF037228 6 894 1.7E-137 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 Gene3D G3DSA:3.90.1200.10 164 549 0.0019 T 28-03-2018 A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 Pfam PF05147 Lanthionine synthetase C-like protein 561 878 5.0E-31 T 28-03-2018 IPR007822 Lanthionine synthetase C-like A21D_RS07780 3ae18f0a790abfcc8f2919f8b7cd2948 896 Pfam PF13575 Domain of unknown function (DUF4135) 96 452 1.4E-74 T 28-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 6.9E-42 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 284 1.9E-28 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 Gene3D G3DSA:3.40.50.720 1 164 5.4E-30 T 28-03-2018 A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 SUPERFAMILY SSF51735 3 163 1.34E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 PIRSF PIRSF000103 1 296 1.5E-70 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 Gene3D G3DSA:1.10.1040.10 167 298 2.8E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS12630 50fd79ce722b238acdab4f0833e8a518 298 SUPERFAMILY SSF48179 167 290 1.59E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Gene3D G3DSA:3.40.50.300 4 79 5.7E-8 T 28-03-2018 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 SMART SM00382 28 236 2.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 SMART SM00382 359 526 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 SUPERFAMILY SSF52540 317 534 9.76E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Gene3D G3DSA:3.40.50.300 307 539 3.7E-47 T 28-03-2018 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Gene3D G3DSA:3.40.50.300 89 306 3.1E-39 T 28-03-2018 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Pfam PF12848 ABC transporter 230 324 7.2E-24 T 28-03-2018 IPR032781 ABC-transporter extension domain A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Pfam PF00005 ABC transporter 351 479 1.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 Pfam PF00005 ABC transporter 20 191 7.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 SUPERFAMILY SSF52540 132 273 2.38E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03120 31e1363d6ce3c6a73fa82ba2dab606bd 544 SUPERFAMILY SSF52540 4 94 2.38E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04455 9233fb0d2044fc17494cd0dcb4594a40 267 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 192 260 2.3E-15 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A21D_RS04455 9233fb0d2044fc17494cd0dcb4594a40 267 Pfam PF00460 Flagella basal body rod protein 5 35 2.4E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A21D_RS04455 9233fb0d2044fc17494cd0dcb4594a40 267 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 166 3.6E-32 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A21D_RS04455 9233fb0d2044fc17494cd0dcb4594a40 267 SUPERFAMILY SSF117143 113 224 1.96E-16 T 28-03-2018 A21D_RS06850 63af598632305ba07abb71dff6c5af55 329 SUPERFAMILY SSF52540 10 197 1.59E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06850 63af598632305ba07abb71dff6c5af55 329 Pfam PF13177 DNA polymerase III, delta subunit 11 169 2.2E-58 T 28-03-2018 A21D_RS06850 63af598632305ba07abb71dff6c5af55 329 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 18 197 3.5E-65 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A21D_RS06850 63af598632305ba07abb71dff6c5af55 329 Gene3D G3DSA:3.40.50.300 10 167 2.0E-31 T 28-03-2018 A21D_RS06850 63af598632305ba07abb71dff6c5af55 329 Gene3D G3DSA:1.20.272.10 208 329 1.0E-19 T 28-03-2018 A21D_RS14070 8bc557bcb4015789eb4cea4ec808946d 464 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 111 460 1.9E-112 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A21D_RS14070 8bc557bcb4015789eb4cea4ec808946d 464 Gene3D G3DSA:3.60.120.10 2 463 2.3E-103 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS14070 8bc557bcb4015789eb4cea4ec808946d 464 SUPERFAMILY SSF56322 45 461 1.7E-103 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS14070 8bc557bcb4015789eb4cea4ec808946d 464 Hamap MF_01935 Isochorismate synthase MenF [menF]. 4 462 29.467 T 28-03-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A21D_RS14070 8bc557bcb4015789eb4cea4ec808946d 464 Pfam PF00425 chorismate binding enzyme 199 452 4.2E-76 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A21D_RS15120 71d04e17a86037f3f687d157a2e18564 258 Pfam PF02602 Uroporphyrinogen-III synthase HemD 21 243 2.9E-47 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS15120 71d04e17a86037f3f687d157a2e18564 258 Gene3D G3DSA:3.40.50.10090 41 161 3.1E-21 T 28-03-2018 A21D_RS15120 71d04e17a86037f3f687d157a2e18564 258 Gene3D G3DSA:3.40.50.10090 162 254 5.4E-18 T 28-03-2018 A21D_RS15120 71d04e17a86037f3f687d157a2e18564 258 SUPERFAMILY SSF69618 7 248 1.57E-53 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS04285 99598c401bbe3176f3535d8c0c87dbf3 399 Gene3D G3DSA:3.40.50.2000 2 215 6.9E-10 T 28-03-2018 A21D_RS04285 99598c401bbe3176f3535d8c0c87dbf3 399 Pfam PF00534 Glycosyl transferases group 1 218 375 1.5E-11 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS04285 99598c401bbe3176f3535d8c0c87dbf3 399 Gene3D G3DSA:3.40.50.2000 216 384 8.0E-17 T 28-03-2018 A21D_RS04285 99598c401bbe3176f3535d8c0c87dbf3 399 SUPERFAMILY SSF53756 4 398 6.91E-37 T 28-03-2018 A21D_RS04285 99598c401bbe3176f3535d8c0c87dbf3 399 Pfam PF13439 Glycosyltransferase Family 4 17 206 3.2E-7 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 2 80 4.7E-6 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 27 164 34.607 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 134 140 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 SUPERFAMILY SSF53155 1 81 3.34E-11 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 86 163 8.9E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 SUPERFAMILY SSF46767 83 164 4.58E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 84 163 1.6E-36 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 Gene3D G3DSA:1.10.10.10 80 165 1.3E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05075 154920bcd4f676140c7e9a3d2a5b7514 168 Gene3D G3DSA:3.30.160.70 1 79 4.4E-13 T 28-03-2018 A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 Gene3D G3DSA:3.30.300.30 325 434 3.0E-8 T 28-03-2018 A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 433 1.2E-23 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 Gene3D G3DSA:3.40.50.980 86 255 6.6E-18 T 28-03-2018 A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 PIRSF PIRSF006444 1 437 6.2E-189 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 Pfam PF00501 AMP-binding enzyme 143 334 2.3E-12 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A21D_RS01885 2012ac84675701c34ff8fe6ae63929c1 440 SUPERFAMILY SSF56801 37 380 5.36E-58 T 28-03-2018 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 41 799 2.7E-277 T 28-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 SMART SM00331 587 799 5.2E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 615 799 2.9E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 SMART SM00332 592 797 8.6E-4 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 Gene3D G3DSA:3.60.40.10 582 809 1.4E-23 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS06685 3d42d7c121d38839c1f7d970de0b2d1b 816 SUPERFAMILY SSF81606 596 800 3.01E-21 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS08175 80494b3b9037365b72c46c2a1f660766 131 Gene3D G3DSA:3.40.50.510 1 130 1.2E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS08175 80494b3b9037365b72c46c2a1f660766 131 Pfam PF03610 PTS system fructose IIA component 3 117 3.5E-17 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS08175 80494b3b9037365b72c46c2a1f660766 131 SUPERFAMILY SSF53062 2 129 4.71E-26 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS08860 9f826049ff90b07ab4513452918573b6 101 Pfam PF14154 Domain of unknown function (DUF4306) 6 85 1.9E-14 T 28-03-2018 IPR025440 Protein of unknown function DUF4306 A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 Pfam PF09419 Mitochondrial PGP phosphatase 4 136 9.7E-9 T 28-03-2018 IPR027706 Mitochondrial PGP phosphatase KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 1.2E-19 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 Gene3D G3DSA:3.40.50.1000 15 156 8.0E-21 T 28-03-2018 IPR023214 HAD-like domain A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 166 2.8E-51 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 60 130 1.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS15535 fd38cd60d40c3e4d32b8faeae068b70f 171 SUPERFAMILY SSF56784 4 150 8.67E-23 T 28-03-2018 IPR023214 HAD-like domain A21D_RS14410 c569ffe60537d4361d6161172bfcde83 564 Pfam PF06160 Septation ring formation regulator, EzrA 3 557 1.2E-160 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A21D_RS14410 c569ffe60537d4361d6161172bfcde83 564 Gene3D G3DSA:1.20.5.50 213 344 0.11 T 28-03-2018 A21D_RS14410 c569ffe60537d4361d6161172bfcde83 564 Gene3D G3DSA:1.20.58.90 66 157 7.5E-4 T 28-03-2018 A21D_RS14410 c569ffe60537d4361d6161172bfcde83 564 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 562 21.056 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A21D_RS14410 c569ffe60537d4361d6161172bfcde83 564 Gene3D G3DSA:1.20.120.330 345 564 1.6E-4 T 28-03-2018 A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 126 9.2E-26 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 Gene3D G3DSA:3.40.350.10 1 125 8.8E-30 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 Pfam PF00557 Metallopeptidase family M24 136 337 2.7E-68 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 SUPERFAMILY SSF55920 83 348 3.27E-82 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 Gene3D G3DSA:3.90.230.10 126 353 1.2E-78 T 28-03-2018 A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 SUPERFAMILY SSF53092 7 126 1.08E-27 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A21D_RS16040 cd0f4aa79a2a9f34c699c95e4a67cffa 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A21D_RS15440 0bd1c3b063b887c983d99aa25677b51b 372 Pfam PF02618 YceG-like family 67 369 3.0E-79 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A21D_RS15440 0bd1c3b063b887c983d99aa25677b51b 372 Gene3D G3DSA:3.30.160.60 344 372 2.0E-8 T 28-03-2018 A21D_RS15440 0bd1c3b063b887c983d99aa25677b51b 372 Gene3D G3DSA:3.30.160.60 100 130 4.6E-6 T 28-03-2018 A21D_RS15440 0bd1c3b063b887c983d99aa25677b51b 372 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 26 371 2.3E-90 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A21D_RS15440 0bd1c3b063b887c983d99aa25677b51b 372 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 31 372 33.111 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A21D_RS07655 bf5f2477e607ef38dc4d20bdaf9d7f32 389 Gene3D G3DSA:3.40.50.1820 7 281 5.2E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07655 bf5f2477e607ef38dc4d20bdaf9d7f32 389 SUPERFAMILY SSF53474 121 256 3.0E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07655 bf5f2477e607ef38dc4d20bdaf9d7f32 389 SUPERFAMILY SSF53474 14 49 3.0E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07655 bf5f2477e607ef38dc4d20bdaf9d7f32 389 Pfam PF01764 Lipase (class 3) 44 240 1.9E-6 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 Hamap MF_01987 Ribokinase [rbsK]. 2 301 23.061 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 Pfam PF00294 pfkB family carbohydrate kinase 2 294 1.5E-58 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 PRINTS PR00990 Ribokinase signature 104 117 7.8E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 PRINTS PR00990 Ribokinase signature 33 52 7.8E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 PRINTS PR00990 Ribokinase signature 173 188 7.8E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 PRINTS PR00990 Ribokinase signature 6 27 7.8E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 PRINTS PR00990 Ribokinase signature 217 228 7.8E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 SUPERFAMILY SSF53613 3 296 8.57E-73 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 Gene3D G3DSA:3.40.1190.20 1 301 3.1E-67 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS13150 df29f334b5190f9dd7cc2823e8c44f4b 306 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 298 1.6E-91 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A21D_RS14300 8d1998a8f4ec421f3564e18b91ca1cc6 269 Pfam PF07285 Protein of unknown function (DUF1444) 3 265 1.8E-124 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 A21D_RS14300 8d1998a8f4ec421f3564e18b91ca1cc6 269 PIRSF PIRSF012562 1 267 2.9E-128 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 A21D_RS14300 8d1998a8f4ec421f3564e18b91ca1cc6 269 Hamap MF_01548 UPF0354 protein . 3 267 45.545 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 A21D_RS19575 7ec6f56daf1194f425b054b02098bda8 196 Pfam PF16219 Domain of unknown function (DUF4879) 79 195 4.4E-19 T 28-03-2018 IPR032624 Protein of unknown function DUF4879 A21D_RS02345 c931e5f0ad52b888ad6df55969292329 221 ProSitePatterns PS00958 Transaldolase active site. 83 100 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS02345 c931e5f0ad52b888ad6df55969292329 221 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 207 4.4E-48 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS02345 c931e5f0ad52b888ad6df55969292329 221 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A21D_RS02345 c931e5f0ad52b888ad6df55969292329 221 SUPERFAMILY SSF51569 1 215 8.58E-64 T 28-03-2018 A21D_RS02345 c931e5f0ad52b888ad6df55969292329 221 Gene3D G3DSA:3.20.20.70 1 221 2.2E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS11345 8574f7f12c75d937e58a74a708337759 159 Gene3D G3DSA:3.40.1260.10 1 159 1.4E-54 T 28-03-2018 A21D_RS11345 8574f7f12c75d937e58a74a708337759 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 158 1.6E-66 T 28-03-2018 IPR032836 DsrE2-like family A21D_RS11345 8574f7f12c75d937e58a74a708337759 159 SUPERFAMILY SSF75169 101 153 5.45E-21 T 28-03-2018 IPR027396 DsrEFH-like A21D_RS11345 8574f7f12c75d937e58a74a708337759 159 SUPERFAMILY SSF75169 5 51 5.45E-21 T 28-03-2018 IPR027396 DsrEFH-like A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 SUPERFAMILY SSF75625 3 242 3.27E-95 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 Gene3D G3DSA:3.30.70.980 83 176 2.4E-34 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 Pfam PF01709 Transcriptional regulator 5 239 3.4E-96 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 36.461 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 Gene3D G3DSA:1.10.10.200 1 78 1.4E-31 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 240 7.1E-98 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS15260 865a64aff0adb41dca006597c3ad68d5 243 Gene3D G3DSA:3.30.70.980 177 243 1.1E-8 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS07315 89d80fb41576654de3ec7d26c0bb7393 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 60 1.1E-30 T 28-03-2018 IPR009296 Protein of unknown function DUF951 A21D_RS07315 89d80fb41576654de3ec7d26c0bb7393 65 PIRSF PIRSF037263 1 65 1.8E-35 T 28-03-2018 IPR009296 Protein of unknown function DUF951 A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 4.6E-38 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 2.9E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 Gene3D G3DSA:3.40.50.970 1 194 4.5E-61 T 28-03-2018 A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 SUPERFAMILY SSF52518 2 204 3.0E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 SMART SM00861 4 179 1.8E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 SUPERFAMILY SSF52922 188 325 2.09E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS18660 ce56f1bcc76b4ebb0c81e65265ebe197 325 Gene3D G3DSA:3.40.50.920 195 324 4.3E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 Gene3D G3DSA:1.10.10.10 3 76 5.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 2.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 Gene3D G3DSA:1.20.120.530 93 173 0.0015 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 SUPERFAMILY SSF48008 98 171 3.66E-5 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.5E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.5E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 SMART SM00345 15 74 3.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS14535 3dce200f4a138a8c02aad29c9c757618 207 SUPERFAMILY SSF46785 5 88 2.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07930 4aaa4dfdab553679345484aad40c4a47 113 SMART SM00530 17 72 3.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS07930 4aaa4dfdab553679345484aad40c4a47 113 Gene3D G3DSA:1.10.260.40 4 111 6.3E-21 T 28-03-2018 A21D_RS07930 4aaa4dfdab553679345484aad40c4a47 113 Pfam PF01381 Helix-turn-helix 20 72 1.8E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS07930 4aaa4dfdab553679345484aad40c4a47 113 SUPERFAMILY SSF47413 11 79 2.0E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 Gene3D G3DSA:1.20.1560.10 1 329 4.6E-69 T 28-03-2018 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 Pfam PF00005 ABC transporter 359 508 3.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 Gene3D G3DSA:3.40.50.300 330 584 1.1E-76 T 28-03-2018 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 SUPERFAMILY SSF52540 333 579 2.28E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 SMART SM00382 368 554 3.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 SUPERFAMILY SSF90123 9 325 3.79E-79 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS11715 341ec21cfa36da3295e06ce27794d44d 587 Pfam PF00664 ABC transporter transmembrane region 22 290 1.5E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS01880 dec6c6f993069dd611e591aa8f1ac085 326 Pfam PF05138 Phenylacetic acid catabolic protein 28 309 3.3E-79 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A21D_RS01880 dec6c6f993069dd611e591aa8f1ac085 326 SUPERFAMILY SSF47240 38 284 1.19E-61 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS01880 dec6c6f993069dd611e591aa8f1ac085 326 Gene3D G3DSA:1.10.620.20 7 302 1.5E-64 T 28-03-2018 A21D_RS01880 dec6c6f993069dd611e591aa8f1ac085 326 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 18 313 2.1E-128 T 28-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 SUPERFAMILY SSF89919 2 111 4.45E-36 T 28-03-2018 IPR023799 Ribosome-binding factor A domain A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 112 2.5E-40 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 Pfam PF02033 Ribosome-binding factor A 5 108 4.5E-34 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 95 1.0E-38 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 113 22.363 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A21D_RS17720 64bbf5258011738d2ab8da4dda129fdb 113 Gene3D G3DSA:3.30.300.20 3 113 1.5E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 Gene3D G3DSA:1.10.580.10 272 348 1.1E-4 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PIRSF PIRSF001369 1 359 1.1E-106 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 Gene3D G3DSA:1.10.580.10 11 254 2.5E-72 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 Pfam PF00285 Citrate synthase, C-terminal domain 7 350 3.5E-100 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 ProSitePatterns PS00480 Citrate synthase signature. 248 260 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 117 130 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 302 318 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 188 216 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 166 181 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 241 261 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 PRINTS PR00143 Citrate synthase signature 322 336 2.7E-33 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS11075 2b8ebc81b100505bc9fc445e9fdfcf08 361 SUPERFAMILY SSF48256 7 358 1.57E-103 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A21D_RS08030 a5c44680fded270301540c8c7a7baed9 104 Gene3D G3DSA:1.20.58.80 5 103 4.5E-30 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS08030 a5c44680fded270301540c8c7a7baed9 104 SUPERFAMILY SSF46973 5 102 2.09E-27 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS08030 a5c44680fded270301540c8c7a7baed9 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 102 4.1E-29 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS08030 a5c44680fded270301540c8c7a7baed9 104 PIRSF PIRSF000699 1 104 2.8E-27 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS18510 f157b408bf5a93fb2e99bdbb934f56eb 355 SUPERFAMILY SSF55797 233 350 1.26E-22 T 28-03-2018 IPR014044 CAP domain A21D_RS18510 f157b408bf5a93fb2e99bdbb934f56eb 355 Pfam PF00188 Cysteine-rich secretory protein family 239 347 1.8E-16 T 28-03-2018 IPR014044 CAP domain A21D_RS18510 f157b408bf5a93fb2e99bdbb934f56eb 355 Pfam PF14504 CAP-associated N-terminal 69 208 6.1E-45 T 28-03-2018 IPR029410 CAP-associated domain A21D_RS18510 f157b408bf5a93fb2e99bdbb934f56eb 355 Gene3D G3DSA:3.40.33.10 226 351 6.6E-16 T 28-03-2018 IPR014044 CAP domain A21D_RS18510 f157b408bf5a93fb2e99bdbb934f56eb 355 Gene3D G3DSA:3.30.1450.10 27 121 0.11 T 28-03-2018 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 Gene3D G3DSA:1.10.287.310 1 65 1.2E-27 T 28-03-2018 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 SUPERFAMILY SSF46561 1 64 1.44E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 Pfam PF00831 Ribosomal L29 protein 4 60 7.2E-27 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.978 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.0E-25 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06335 f30a97c86fc9fd6188b9896507c632fd 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS14795 23ba53cc9989cf80889a1678a9f4d8c8 252 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 93 113 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS14795 23ba53cc9989cf80889a1678a9f4d8c8 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 2 251 4.8E-68 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS14795 23ba53cc9989cf80889a1678a9f4d8c8 252 Gene3D G3DSA:3.90.226.10 1 202 3.0E-68 T 28-03-2018 A21D_RS14795 23ba53cc9989cf80889a1678a9f4d8c8 252 SUPERFAMILY SSF52096 2 251 7.68E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS14795 23ba53cc9989cf80889a1678a9f4d8c8 252 Gene3D G3DSA:1.10.12.10 203 250 9.3E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS04520 63a4b4fd6bb4654427e142ec8cf3fccd 244 Gene3D G3DSA:3.30.360.40 170 244 2.2E-17 T 28-03-2018 A21D_RS04520 63a4b4fd6bb4654427e142ec8cf3fccd 244 Gene3D G3DSA:3.30.2030.10 34 165 1.4E-19 T 28-03-2018 A21D_RS04520 63a4b4fd6bb4654427e142ec8cf3fccd 244 Pfam PF08680 TATA-box binding 51 244 2.8E-22 T 28-03-2018 IPR014794 TATA-box binding A21D_RS04520 63a4b4fd6bb4654427e142ec8cf3fccd 244 SUPERFAMILY SSF143842 37 241 4.32E-17 T 28-03-2018 IPR014794 TATA-box binding A21D_RS17100 bf56a0bdf9f8001fb35b98c021047157 74 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 74 28.242 T 28-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A21D_RS17100 bf56a0bdf9f8001fb35b98c021047157 74 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 7 73 1.0E-28 T 28-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 6.3E-63 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.083 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 Gene3D G3DSA:3.30.230.40 2 88 1.2E-30 T 28-03-2018 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 SUPERFAMILY SSF54211 1 85 2.4E-29 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 Gene3D G3DSA:3.30.230.40 90 194 8.0E-31 T 28-03-2018 A21D_RS03035 61eb5a94aebd560ce07f382dd48ed411 194 SUPERFAMILY SSF54211 88 178 8.47E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A21D_RS00395 ed0e2f069138384a4a005c3e4184d05d 116 Gene3D G3DSA:3.20.20.30 1 116 2.2E-29 T 28-03-2018 A21D_RS00395 ed0e2f069138384a4a005c3e4184d05d 116 SUPERFAMILY SSF51679 1 111 3.53E-30 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A21D_RS00395 ed0e2f069138384a4a005c3e4184d05d 116 Pfam PF00296 Luciferase-like monooxygenase 19 109 9.2E-17 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A21D_RS19625 b096e1a48d0b589baef9c9155f9bca58 368 Pfam PF14594 Siphovirus ReqiPepy6 Gp37-like protein 11 345 7.3E-102 T 28-03-2018 IPR029432 Siphovirus Gp37-like protein A21D_RS01575 72dcddb780d9daa24d6bb4580682dd92 110 Gene3D G3DSA:1.10.287.1080 1 110 1.6E-16 T 28-03-2018 A21D_RS01575 72dcddb780d9daa24d6bb4580682dd92 110 SUPERFAMILY SSF101386 1 103 1.2E-22 T 28-03-2018 A21D_RS01575 72dcddb780d9daa24d6bb4580682dd92 110 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 6.8E-13 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS01575 72dcddb780d9daa24d6bb4580682dd92 110 PIRSF PIRSF036521 1 107 1.6E-47 T 28-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related A21D_RS17635 40736be19cc3bb558798f80a6a4dc124 370 Gene3D G3DSA:3.40.50.2300 48 167 4.1E-44 T 28-03-2018 A21D_RS17635 40736be19cc3bb558798f80a6a4dc124 370 SUPERFAMILY SSF53822 65 283 2.49E-13 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS17635 40736be19cc3bb558798f80a6a4dc124 370 Gene3D G3DSA:3.40.50.2300 168 365 4.1E-44 T 28-03-2018 A21D_RS17635 40736be19cc3bb558798f80a6a4dc124 370 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 53 358 1.1E-81 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A21D_RS12965 40ddd44362376b73e8dee683b1411751 77 Pfam PF08858 IDEAL domain 35 69 1.1E-6 T 28-03-2018 IPR014957 IDEAL domain A21D_RS12965 40ddd44362376b73e8dee683b1411751 77 SMART SM00914 35 71 0.0014 T 28-03-2018 IPR014957 IDEAL domain A21D_RS03330 c985c728d546b1dc676bc44060290ceb 43 Pfam PF14151 YfhD-like protein 2 43 1.6E-17 T 28-03-2018 IPR025435 YfhD-like protein A21D_RS14910 855ddf4b40f66eca5865e9b5d0ffd365 137 Gene3D G3DSA:1.20.1640.10 26 129 5.6E-4 T 28-03-2018 A21D_RS14910 855ddf4b40f66eca5865e9b5d0ffd365 137 Pfam PF13273 Protein of unknown function (DUF4064) 2 108 1.8E-14 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 A21D_RS18750 e387978267e767bfcc6c58761e67839d 157 Pfam PF14177 YkyB-like protein 7 141 1.5E-58 T 28-03-2018 IPR025552 YkyB-like protein A21D_RS02095 bf90e35e7ec67b116c9c2e3040eef34a 391 Gene3D G3DSA:1.10.10.60 304 364 2.0E-7 T 28-03-2018 A21D_RS02095 bf90e35e7ec67b116c9c2e3040eef34a 391 Pfam PF05651 Putative sugar diacid recognition 15 147 3.4E-45 T 28-03-2018 IPR008599 Putative sugar diacid recognition A21D_RS02095 bf90e35e7ec67b116c9c2e3040eef34a 391 Pfam PF13556 PucR C-terminal helix-turn-helix domain 330 382 2.3E-14 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 3.9E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.5E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.5E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.5E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 Gene3D G3DSA:3.30.860.10 1 92 4.0E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 Pfam PF00203 Ribosomal protein S19 3 83 9.1E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.571 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 SUPERFAMILY SSF54570 3 84 5.75E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06355 831ac6b8e4cf0f9a6284cc56c6aa0948 92 PIRSF PIRSF002144 1 92 5.5E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 SUPERFAMILY SSF48179 185 285 1.96E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 SUPERFAMILY SSF51735 6 185 2.03E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 1.3E-31 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 183 1.6E-55 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 PIRSF PIRSF000105 1 287 3.8E-83 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 Gene3D G3DSA:3.40.50.720 5 184 2.8E-49 T 28-03-2018 A21D_RS01840 4e39ec8b0f8cc4a56afbad3bc77580ea 287 Gene3D G3DSA:1.10.1040.10 185 286 2.4E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A21D_RS00900 50c7626a677e3d7aa01e3fd4e8b19e0b 397 Gene3D G3DSA:2.60.40.10 190 272 4.0E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS00900 50c7626a677e3d7aa01e3fd4e8b19e0b 397 Pfam PF16403 Domain of unknown function (DUF5011) 196 267 4.0E-26 T 28-03-2018 IPR032179 Domain of unknown function DUF5011 A21D_RS02640 3ad042f3f27d584d909f6597b4d654e6 364 Pfam PF00534 Glycosyl transferases group 1 186 336 2.9E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS02640 3ad042f3f27d584d909f6597b4d654e6 364 SUPERFAMILY SSF53756 20 362 4.08E-62 T 28-03-2018 A21D_RS02640 3ad042f3f27d584d909f6597b4d654e6 364 Gene3D G3DSA:3.40.50.2000 14 182 2.9E-14 T 28-03-2018 A21D_RS02640 3ad042f3f27d584d909f6597b4d654e6 364 Gene3D G3DSA:3.40.50.2000 183 346 2.3E-33 T 28-03-2018 A21D_RS02640 3ad042f3f27d584d909f6597b4d654e6 364 Pfam PF13477 Glycosyl transferase 4-like 3 147 5.2E-27 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A21D_RS07515 2c51761f719d44a492552508b6743a41 119 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 3 119 7.8E-57 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 A21D_RS07515 2c51761f719d44a492552508b6743a41 119 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 5 117 3.9E-41 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 A21D_RS07515 2c51761f719d44a492552508b6743a41 119 Gene3D G3DSA:3.30.1330.20 2 118 4.0E-44 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A21D_RS07985 0149d0f08823a5d42621bdca9bc49b46 212 Gene3D G3DSA:1.10.3720.10 2 212 5.3E-28 T 28-03-2018 A21D_RS07985 0149d0f08823a5d42621bdca9bc49b46 212 SUPERFAMILY SSF161098 18 202 2.75E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07985 0149d0f08823a5d42621bdca9bc49b46 212 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 209 3.7E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS11200 e07a5769a44a5d16139c9196cb2d2d4c 406 Pfam PF07690 Major Facilitator Superfamily 18 276 1.5E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS11200 e07a5769a44a5d16139c9196cb2d2d4c 406 ProSitePatterns PS00217 Sugar transport proteins signature 2. 318 343 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A21D_RS11200 e07a5769a44a5d16139c9196cb2d2d4c 406 SUPERFAMILY SSF103473 1 396 3.01E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS11200 e07a5769a44a5d16139c9196cb2d2d4c 406 Gene3D G3DSA:1.20.1250.20 4 200 8.6E-34 T 28-03-2018 A21D_RS11200 e07a5769a44a5d16139c9196cb2d2d4c 406 Gene3D G3DSA:1.20.1250.20 202 400 1.0E-21 T 28-03-2018 A21D_RS08060 058a03cea498c5f3003ddb0b6ef3b0bf 293 Pfam PF03313 Serine dehydratase alpha chain 15 276 4.7E-69 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A21D_RS08060 058a03cea498c5f3003ddb0b6ef3b0bf 293 Gene3D G3DSA:1.10.4100.10 89 271 1.9E-25 T 28-03-2018 A21D_RS08060 058a03cea498c5f3003ddb0b6ef3b0bf 293 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 290 9.8E-113 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 Pfam PF04055 Radical SAM superfamily 23 92 3.3E-9 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 PIRSF PIRSF000368 1 159 1.0E-50 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 Pfam PF13353 4Fe-4S single cluster domain 15 148 6.2E-37 T 28-03-2018 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 7 151 8.4E-47 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 Gene3D G3DSA:3.20.20.70 18 126 2.3E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 SUPERFAMILY SSF102114 23 106 2.75E-9 T 28-03-2018 A21D_RS09585 73d3872fd0bf7055b5e977a616863d7f 160 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 A21D_RS11475 daeafdfe90c76cdce7d8973c7af3e418 517 Pfam PF03553 Na+/H+ antiporter family 162 489 9.1E-71 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS16075 715b3dd24e1ee5043b74b5812339d84a 206 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 197 2.1E-29 T 28-03-2018 IPR014245 Sporulation stage III, protein AF A21D_RS16075 715b3dd24e1ee5043b74b5812339d84a 206 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 113 8.3E-31 T 28-03-2018 IPR014245 Sporulation stage III, protein AF A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 Pfam PF00037 4Fe-4S binding domain 33 56 2.2E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 SUPERFAMILY SSF54862 3 70 8.66E-20 T 28-03-2018 A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.6E-12 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.6E-12 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.6E-12 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 Gene3D G3DSA:3.30.70.20 45 87 1.0E-9 T 28-03-2018 A21D_RS01890 b0f1bb4abb472df409fb519327e41896 89 Gene3D G3DSA:3.30.70.20 2 44 7.4E-13 T 28-03-2018 A21D_RS05545 404d23831ccab7ae102b5957862a0b7b 73 Pfam PF00403 Heavy-metal-associated domain 6 65 1.6E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS05545 404d23831ccab7ae102b5957862a0b7b 73 SUPERFAMILY SSF55008 2 68 2.62E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A21D_RS05545 404d23831ccab7ae102b5957862a0b7b 73 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A21D_RS05545 404d23831ccab7ae102b5957862a0b7b 73 Gene3D G3DSA:3.30.70.100 1 69 2.3E-19 T 28-03-2018 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:1.10.1790.10 202 298 4.2E-4 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:1.10.10.10 4 71 6.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 SUPERFAMILY SSF46785 7 50 1.28E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:1.10.10.10 76 158 1.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 SUPERFAMILY SSF52794 424 504 1.1E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Pfam PF08279 HTH domain 10 57 3.8E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:1.10.1790.10 299 416 1.1E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 SUPERFAMILY SSF63520 314 413 2.09E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Pfam PF05043 Mga helix-turn-helix domain 97 170 1.4E-4 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:3.40.50.2300 422 510 2.0E-16 T 28-03-2018 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Gene3D G3DSA:3.40.930.10 557 702 8.5E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 563 700 1.3E-26 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 SUPERFAMILY SSF55804 559 700 2.09E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS12270 bd1f73af50f0ae6c628d61314480bd9d 707 Pfam PF00874 PRD domain 322 411 2.3E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS02780 1a5c7f70a2dbb22f7c4ea81cb19efbc3 329 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS02780 1a5c7f70a2dbb22f7c4ea81cb19efbc3 329 SUPERFAMILY SSF53098 160 309 9.29E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS02780 1a5c7f70a2dbb22f7c4ea81cb19efbc3 329 Pfam PF00665 Integrase core domain 164 265 1.2E-7 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS02780 1a5c7f70a2dbb22f7c4ea81cb19efbc3 329 Gene3D G3DSA:3.30.420.10 150 318 2.1E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 PIRSF PIRSF006250 1 265 3.4E-92 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 97 260 2.3E-60 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 Gene3D G3DSA:3.20.20.70 118 253 4.6E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 SUPERFAMILY SSF51690 97 262 1.22E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 2 261 2.1E-98 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 SUPERFAMILY SSF54675 2 96 2.59E-24 T 28-03-2018 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 6 95 4.8E-23 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A21D_RS03455 f12299d6f431c7aa293e90c4044b6819 265 Gene3D G3DSA:3.90.1170.20 1 117 7.6E-33 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 101 6.0E-17 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 18.128 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 29.558 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 SUPERFAMILY SSF141734 2 111 3.53E-47 T 28-03-2018 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Gene3D G3DSA:1.10.287.1080 112 205 7.1E-18 T 28-03-2018 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 116 201 2.7E-13 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 101 3.9E-34 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 116 198 6.0E-28 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 SUPERFAMILY SSF101386 116 202 7.48E-23 T 28-03-2018 A21D_RS03055 5674b113beb609df5be59bac78fec1cb 210 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 203 35.795 T 28-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A21D_RS16960 acd19277cfd1107a74137fd2440aa3b7 307 SUPERFAMILY SSF110296 59 300 1.31E-22 T 28-03-2018 A21D_RS16960 acd19277cfd1107a74137fd2440aa3b7 307 Gene3D G3DSA:2.120.10.10 208 307 5.3E-9 T 28-03-2018 A21D_RS16960 acd19277cfd1107a74137fd2440aa3b7 307 Gene3D G3DSA:2.120.10.10 12 207 2.5E-10 T 28-03-2018 A21D_RS03345 08276cadc6d62513236d5ff97d35f1ba 155 SMART SM00850 50 147 8.7E-17 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS03345 08276cadc6d62513236d5ff97d35f1ba 155 Gene3D G3DSA:2.40.50.40 41 109 1.1E-9 T 28-03-2018 A21D_RS03345 08276cadc6d62513236d5ff97d35f1ba 155 Pfam PF04397 LytTr DNA-binding domain 51 146 2.2E-16 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS04315 91a143b133ea16031a95342f9743dcc1 358 ProSitePatterns PS01348 MraY family signature 2. 149 160 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS04315 91a143b133ea16031a95342f9743dcc1 358 Pfam PF00953 Glycosyl transferase family 4 77 229 2.4E-38 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 SUPERFAMILY SSF53098 97 309 2.73E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 303 8.2E-78 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 311 29.213 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 Gene3D G3DSA:3.30.420.10 95 310 3.5E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 Pfam PF11858 Domain of unknown function (DUF3378) 4 74 1.2E-21 T 28-03-2018 IPR024568 Ribonuclease HIII, N-terminal A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 PIRSF PIRSF037748 1 312 4.6E-106 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 A21D_RS14755 6ede5e33f10873706dc9eb51d56ae62e 312 Pfam PF01351 Ribonuclease HII 98 304 2.3E-41 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 7.0E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 7.0E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 7.0E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 7.0E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 7.0E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15515 fd8f8ccd31fe4cc9aea751eded4a9709 493 Pfam PF00361 Proton-conducting membrane transporter 127 416 3.6E-50 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS04500 15f7ad986744a084fd865b8f91e56342 321 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 43 95 4.0E-18 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A21D_RS04500 15f7ad986744a084fd865b8f91e56342 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 321 4.5E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS04500 15f7ad986744a084fd865b8f91e56342 321 Gene3D G3DSA:1.10.3720.10 43 309 5.3E-48 T 28-03-2018 A21D_RS04500 15f7ad986744a084fd865b8f91e56342 321 SUPERFAMILY SSF161098 113 300 4.06E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 21 267 2.5E-101 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 Pfam PF04962 KduI/IolB family 13 267 4.4E-102 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 Gene3D G3DSA:2.60.120.10 125 271 1.9E-57 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 Gene3D G3DSA:2.60.120.10 19 124 7.4E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 SUPERFAMILY SSF51182 9 256 1.75E-67 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS01975 3bc4da6838e143fdce975e813151cb2d 271 PIRSF PIRSF036628 1 271 2.0E-107 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 SUPERFAMILY SSF52540 30 274 2.0E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 SMART SM00382 54 252 5.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 Pfam PF00005 ABC transporter 46 202 5.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 PIRSF PIRSF037116 1 28 13.0 T 28-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 PIRSF PIRSF037116 23 279 9.2E-84 T 28-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS08240 717282cc4c877ab8366afdafb2f7d8fe 279 Gene3D G3DSA:3.40.50.300 3 278 5.1E-57 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 Gene3D G3DSA:1.20.1250.20 265 473 1.5E-27 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 Gene3D G3DSA:1.20.1250.20 8 204 2.1E-34 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 SUPERFAMILY SSF103473 12 201 7.94E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 SUPERFAMILY SSF103473 254 467 7.94E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 Pfam PF07690 Major Facilitator Superfamily 25 415 3.3E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 426 5.8E-117 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 3.5E-8 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 83 105 3.5E-8 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 3.5E-8 T 28-03-2018 A21D_RS01475 d150020acd6a33efbf179bae2872c8c6 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 3.5E-8 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Pfam PF11563 Protoglobin 20 163 1.3E-19 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Pfam PF13682 Chemoreceptor zinc-binding domain 456 521 2.2E-14 T 28-03-2018 IPR025991 Chemoreceptor zinc-binding domain A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 SUPERFAMILY SSF46458 17 156 1.1E-16 T 28-03-2018 IPR009050 Globin-like A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Gene3D G3DSA:1.10.490.10 13 156 5.5E-15 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Gene3D G3DSA:1.20.1480.30 157 220 0.027 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 SUPERFAMILY SSF58104 162 433 9.81E-56 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 278 305 9.4E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 307 336 9.4E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 201 230 9.4E-17 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Gene3D G3DSA:1.10.287.950 221 434 8.5E-42 T 28-03-2018 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 248 405 1.4E-35 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS10890 9fcbcb5ba42b9b094cc39843c5f8866f 558 SMART SM00283 180 444 2.0E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 Gene3D G3DSA:3.20.20.70 1 218 2.4E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 2 217 36.445 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 213 2.1E-87 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 Pfam PF01791 DeoC/LacD family aldolase 5 213 6.5E-23 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 PIRSF PIRSF001357 1 221 3.2E-77 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 SUPERFAMILY SSF51569 2 215 5.76E-83 T 28-03-2018 A21D_RS15665 2e60ee4bb3b06678b00bdb678b71c155 222 SMART SM01133 3 215 4.5E-102 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A21D_RS12810 e058b8a3efe1a84c9002a06a4a241ae3 290 Gene3D G3DSA:3.30.470.10 5 122 3.5E-25 T 28-03-2018 A21D_RS12810 e058b8a3efe1a84c9002a06a4a241ae3 290 Gene3D G3DSA:3.20.10.10 123 284 5.0E-40 T 28-03-2018 A21D_RS12810 e058b8a3efe1a84c9002a06a4a241ae3 290 Pfam PF01063 Amino-transferase class IV 33 254 1.2E-48 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS12810 e058b8a3efe1a84c9002a06a4a241ae3 290 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 9 277 8.9E-103 T 28-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 A21D_RS12810 e058b8a3efe1a84c9002a06a4a241ae3 290 SUPERFAMILY SSF56752 12 276 1.01E-73 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A21D_RS13105 7cf9eb32ba78f3649197502e41bb57ca 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 282 6.4E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS13105 7cf9eb32ba78f3649197502e41bb57ca 285 SUPERFAMILY SSF161098 91 276 5.63E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS13105 7cf9eb32ba78f3649197502e41bb57ca 285 Gene3D G3DSA:1.10.3720.10 50 285 1.0E-32 T 28-03-2018 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 SMART SM00862 152 228 1.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 Gene3D G3DSA:1.10.10.10 118 234 9.4E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 SMART SM00448 3 113 1.6E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 SUPERFAMILY SSF52172 2 126 5.55E-44 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 5.2E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 SUPERFAMILY SSF46894 130 229 4.25E-33 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 Pfam PF00072 Response regulator receiver domain 5 114 1.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07380 e18d5cf5d5ea314ba08c2ace7d4a60ea 234 Gene3D G3DSA:3.40.50.2300 2 117 1.9E-37 T 28-03-2018 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 251 3.0E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 197 214 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 SUPERFAMILY SSF64005 21 247 1.44E-89 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 251 1.6E-90 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 Gene3D G3DSA:3.40.1180.10 10 253 6.1E-94 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A21D_RS17770 574dad92dd554dda12a9bf3cab7b3ed5 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 252 40.601 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A21D_RS11615 2c2e59ba9a2ca5901a17e957bf46d6fb 290 SUPERFAMILY SSF56281 31 277 9.83E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11615 2c2e59ba9a2ca5901a17e957bf46d6fb 290 Pfam PF00753 Metallo-beta-lactamase superfamily 40 230 1.2E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11615 2c2e59ba9a2ca5901a17e957bf46d6fb 290 Gene3D G3DSA:3.60.15.10 19 284 3.7E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS11615 2c2e59ba9a2ca5901a17e957bf46d6fb 290 SMART SM00849 42 234 2.6E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS10415 ca64094b78c85566034267b16e2b0cc1 118 ProDom PD031312 YQBH LIN1274 PHAGE XKDH PHAGE-LIKE PBSX RELATED ELEMENT 1 114 2.0E-32 T 28-03-2018 IPR024556 Protein of unknown function DUF3599 A21D_RS10415 ca64094b78c85566034267b16e2b0cc1 118 Pfam PF12206 Domain of unknown function (DUF3599) 1 115 4.7E-42 T 28-03-2018 IPR024556 Protein of unknown function DUF3599 A21D_RS17600 a433bf8253e9b41b5e0bf57160282f34 84 PIRSF PIRSF004764 1 83 6.8E-26 T 28-03-2018 IPR024702 Uncharacterised conserved protein YmfJ A21D_RS17600 a433bf8253e9b41b5e0bf57160282f34 84 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 3.1E-32 T 28-03-2018 IPR021637 Protein of unknown function DUF3243 A21D_RS05125 4886e528b40c1c198e3a6ba254e7d6dd 346 Pfam PF12395 Protein of unknown function 230 342 7.7E-32 T 28-03-2018 IPR022123 Protein of unknown function DUF3658 A21D_RS05125 4886e528b40c1c198e3a6ba254e7d6dd 346 Pfam PF08874 Domain of unknown function (DUF1835) 72 193 3.4E-34 T 28-03-2018 IPR014973 Protein of unknown function DUF1835 A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 Gene3D G3DSA:3.30.750.24 419 557 2.8E-28 T 28-03-2018 IPR002645 STAS domain A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 Pfam PF01740 STAS domain 440 537 7.1E-17 T 28-03-2018 IPR002645 STAS domain A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 ProSitePatterns PS01130 SLC26A transporters signature. 49 70 - T 28-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 SUPERFAMILY SSF52091 442 552 3.92E-16 T 28-03-2018 IPR002645 STAS domain A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 TIGRFAM TIGR00815 sulP: sulfate permease 7 548 1.8E-153 T 28-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 A21D_RS11370 116c148295923c7f7a80fc72d6a1b83b 560 Pfam PF00916 Sulfate permease family 20 389 9.5E-114 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A21D_RS13485 20eaf07e1aad2a7e3f82ba38d78f0e58 602 Pfam PF01432 Peptidase family M3 208 587 3.0E-81 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A21D_RS13485 20eaf07e1aad2a7e3f82ba38d78f0e58 602 Gene3D G3DSA:1.10.1370.10 54 600 1.4E-47 T 28-03-2018 A21D_RS13485 20eaf07e1aad2a7e3f82ba38d78f0e58 602 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 11 598 5.3E-216 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A21D_RS13485 20eaf07e1aad2a7e3f82ba38d78f0e58 602 SUPERFAMILY SSF55486 59 602 2.28E-139 T 28-03-2018 A21D_RS13485 20eaf07e1aad2a7e3f82ba38d78f0e58 602 Pfam PF08439 Oligopeptidase F 118 187 1.4E-23 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 SUPERFAMILY SSF53383 1 424 5.27E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 Gene3D G3DSA:3.90.1150.10 1 165 1.2E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 6.0E-194 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 Gene3D G3DSA:3.40.640.10 169 313 8.9E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 426 102.259 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 Gene3D G3DSA:3.90.1150.10 314 427 3.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS15130 ebc20a1a0e104834b145e7c41662e66f 427 Pfam PF00202 Aminotransferase class-III 33 397 5.9E-76 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 SUPERFAMILY SSF52540 2 645 8.55E-187 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Gene3D G3DSA:3.40.50.300 285 388 5.8E-29 T 28-03-2018 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Pfam PF13361 UvrD-like helicase C-terminal domain 280 619 5.5E-75 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Gene3D G3DSA:3.40.50.300 393 698 1.6E-52 T 28-03-2018 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 737 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 4.6E-86 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Gene3D G3DSA:3.40.50.300 2 155 4.9E-30 T 28-03-2018 A21D_RS11000 f1ba09689a8d8d81512caf472ae5127a 740 Gene3D G3DSA:3.40.50.300 156 284 6.3E-34 T 28-03-2018 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 SMART SM00382 323 508 5.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 SMART SM00382 28 229 4.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 Pfam PF00005 ABC transporter 314 459 5.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 Pfam PF00005 ABC transporter 20 170 1.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 SUPERFAMILY SSF52540 2 236 3.65E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 Gene3D G3DSA:3.40.50.300 1 246 6.8E-56 T 28-03-2018 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 Gene3D G3DSA:3.40.50.300 295 541 1.8E-60 T 28-03-2018 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 SUPERFAMILY SSF52540 296 527 2.56E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09680 00d2b12a4246f2817b63b9f62748eafa 550 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS13760 e7f0eaba1346d7270283d326329bdc0f 194 Pfam PF04203 Sortase family 71 191 3.8E-23 T 28-03-2018 IPR005754 Sortase family A21D_RS13760 e7f0eaba1346d7270283d326329bdc0f 194 SUPERFAMILY SSF63817 63 192 1.96E-31 T 28-03-2018 IPR023365 Sortase domain A21D_RS13760 e7f0eaba1346d7270283d326329bdc0f 194 Gene3D G3DSA:2.40.260.10 24 194 1.4E-27 T 28-03-2018 IPR023365 Sortase domain A21D_RS13760 e7f0eaba1346d7270283d326329bdc0f 194 TIGRFAM TIGR01076 sortase_fam: sortase 71 177 7.0E-22 T 28-03-2018 IPR005754 Sortase family A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 Gene3D G3DSA:2.40.10.10 131 239 1.9E-28 T 28-03-2018 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 Pfam PF13365 Trypsin-like peptidase domain 79 215 1.4E-26 T 28-03-2018 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 PRINTS PR00834 HtrA/DegQ protease family signature 185 202 2.5E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 PRINTS PR00834 HtrA/DegQ protease family signature 109 129 2.5E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 PRINTS PR00834 HtrA/DegQ protease family signature 88 100 2.5E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 2.5E-24 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 SUPERFAMILY SSF50494 54 241 1.75E-43 T 28-03-2018 IPR009003 Peptidase S1, PA clan A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 Gene3D G3DSA:2.40.10.10 39 130 3.3E-21 T 28-03-2018 A21D_RS18795 ba9c52c33857291fec0fabb338aa6086 377 Gene3D G3DSA:3.10.450.100 268 376 0.0026 T 28-03-2018 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 Gene3D G3DSA:1.10.260.40 2 57 3.3E-23 T 28-03-2018 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 SUPERFAMILY SSF47413 1 59 3.19E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 Gene3D G3DSA:3.40.50.2300 159 327 5.4E-47 T 28-03-2018 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.6E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.6E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 Gene3D G3DSA:3.40.50.2300 58 158 1.2E-25 T 28-03-2018 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 SUPERFAMILY SSF53822 60 325 6.52E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 SMART SM00354 1 71 3.2E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS10660 eed5a7cd1345d5f2017838a835036595 328 Pfam PF13377 Periplasmic binding protein-like domain 165 324 1.3E-30 T 28-03-2018 A21D_RS05740 d94325c06c0ea900c90eed37604e7c1c 389 Gene3D G3DSA:3.40.50.1970 9 183 3.8E-39 T 28-03-2018 A21D_RS05740 d94325c06c0ea900c90eed37604e7c1c 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 370 1.1E-77 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS05740 d94325c06c0ea900c90eed37604e7c1c 389 SUPERFAMILY SSF56796 1 386 3.79E-92 T 28-03-2018 A21D_RS05740 d94325c06c0ea900c90eed37604e7c1c 389 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS05740 d94325c06c0ea900c90eed37604e7c1c 389 Gene3D G3DSA:1.20.1090.10 188 389 3.1E-36 T 28-03-2018 A21D_RS02280 86b09d84bab2e5573b54298eda9ebd70 268 Pfam PF02361 Cobalt transport protein 15 236 6.3E-36 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A21D_RS02000 0d22271cdb8ac15a8c408e57b25d49f7 531 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 440 1.1E-74 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS02000 0d22271cdb8ac15a8c408e57b25d49f7 531 Pfam PF00474 Sodium:solute symporter family 35 438 1.2E-50 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS08890 e6e305eb426b6761221101b22769ca0f 166 Pfam PF07681 DoxX 14 111 3.6E-11 T 28-03-2018 IPR032808 DoxX family A21D_RS08890 e6e305eb426b6761221101b22769ca0f 166 Gene3D G3DSA:3.90.1720.10 3 121 7.4E-4 T 28-03-2018 A21D_RS03020 e4dbd508100aa3c107038dc330868915 412 SUPERFAMILY SSF55681 16 321 2.19E-51 T 28-03-2018 A21D_RS03020 e4dbd508100aa3c107038dc330868915 412 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 14 374 25.572 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A21D_RS03020 e4dbd508100aa3c107038dc330868915 412 Pfam PF13393 Histidyl-tRNA synthetase 17 314 2.6E-60 T 28-03-2018 A21D_RS03020 e4dbd508100aa3c107038dc330868915 412 PIRSF PIRSF001549 10 388 4.1E-54 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A21D_RS03020 e4dbd508100aa3c107038dc330868915 412 Gene3D G3DSA:3.30.930.10 7 326 2.0E-48 T 28-03-2018 A21D_RS08440 677b8beb4b9d0db184111bd33c44b11b 256 Pfam PF07070 SpoOM protein 2 213 3.4E-68 T 28-03-2018 IPR009776 Sporulation stage 0, protein M A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 Gene3D G3DSA:3.10.28.20 215 292 7.6E-18 T 28-03-2018 A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 Pfam PF03069 Acetamidase/Formamidase family 18 139 1.8E-9 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 Pfam PF03069 Acetamidase/Formamidase family 145 212 7.6E-21 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 SUPERFAMILY SSF141130 4 291 1.07E-82 T 28-03-2018 A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 Gene3D G3DSA:2.60.120.580 116 211 6.6E-32 T 28-03-2018 A21D_RS12035 2f922a2a9538838e55ffb85307d0050a 299 Gene3D G3DSA:2.60.120.580 1 115 8.5E-24 T 28-03-2018 A21D_RS02940 755ad1293d1786967c899fb0262e7753 161 Pfam PF04306 Protein of unknown function (DUF456) 22 158 5.2E-39 T 28-03-2018 IPR007403 Protein of unknown function DUF456 A21D_RS04570 d52f2d9e5befa837ebc249acf7778fd0 128 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 24 115 2.0E-18 T 28-03-2018 A21D_RS04570 d52f2d9e5befa837ebc249acf7778fd0 128 Pfam PF03899 ATP synthase I chain 10 105 2.2E-16 T 28-03-2018 IPR005598 ATP synthase protein I A21D_RS05645 2d54d70a6031916145a75dd02c1351f1 212 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 192 5.9E-68 T 28-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A21D_RS05645 2d54d70a6031916145a75dd02c1351f1 212 PIRSF PIRSF029886 1 196 2.3E-82 T 28-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A21D_RS05645 2d54d70a6031916145a75dd02c1351f1 212 SMART SM01251 17 193 3.0E-93 T 28-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A21D_RS02575 affc909ac0625d1746fa4522fc36dfbe 210 Gene3D G3DSA:3.40.50.880 1 210 2.3E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS02575 affc909ac0625d1746fa4522fc36dfbe 210 SUPERFAMILY SSF52317 4 178 2.02E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS02575 affc909ac0625d1746fa4522fc36dfbe 210 Pfam PF01965 DJ-1/PfpI family 4 176 1.4E-33 T 28-03-2018 IPR002818 DJ-1/PfpI A21D_RS08140 f368df6c5b91285194e238f55155cf97 308 SUPERFAMILY SSF52833 36 238 4.29E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS08140 f368df6c5b91285194e238f55155cf97 308 Pfam PF13743 Thioredoxin 39 231 5.2E-36 T 28-03-2018 A21D_RS08140 f368df6c5b91285194e238f55155cf97 308 Gene3D G3DSA:3.40.30.10 34 243 4.2E-27 T 28-03-2018 A21D_RS12070 322aafaac6b30f8348620aa3716aa8a2 536 Pfam PF13751 Transposase DDE domain 393 518 5.3E-32 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS12070 322aafaac6b30f8348620aa3716aa8a2 536 Pfam PF05598 Transposase domain (DUF772) 62 129 9.0E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS12070 322aafaac6b30f8348620aa3716aa8a2 536 Gene3D G3DSA:3.90.350.10 230 497 1.2E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS02535 4983b86101c5fe3d121cc80f6ee5db00 179 Pfam PF13302 Acetyltransferase (GNAT) domain 8 149 9.9E-31 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS02535 4983b86101c5fe3d121cc80f6ee5db00 179 Gene3D G3DSA:3.40.630.30 3 170 1.1E-23 T 28-03-2018 A21D_RS02535 4983b86101c5fe3d121cc80f6ee5db00 179 SUPERFAMILY SSF55729 1 163 1.66E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 Gene3D G3DSA:3.20.20.105 1 374 1.2E-160 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 SUPERFAMILY SSF51713 3 369 9.29E-160 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 373 2.2E-184 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 5.4E-91 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 56.894 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS15285 599f1a72157350c009ce7cf088f3ca0d 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 373 6.3E-174 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 PIRSF PIRSF001423 1 555 1.5E-283 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Pfam PF17391 Urocanase N-terminal domain 7 133 2.4E-63 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 2.7E-281 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 SUPERFAMILY SSF111326 3 552 7.72E-253 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Gene3D G3DSA:3.40.1770.10 192 551 6.0E-159 T 28-03-2018 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Gene3D G3DSA:3.40.1770.10 5 147 3.4E-28 T 28-03-2018 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Hamap MF_00577 Urocanate hydratase [hutU]. 3 552 49.974 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Pfam PF01175 Urocanase Rossmann-like domain 136 345 5.3E-86 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS12555 2b3112eab6a3297fc149208e5b1490bf 555 Pfam PF17392 Urocanase C-terminal domain 348 542 2.3E-93 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A21D_RS17595 82910ac1bdfd086cb5cb01bc82d3a349 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 1.2E-102 T 28-03-2018 IPR024514 Domain of unknown function DUF3388 A21D_RS17595 82910ac1bdfd086cb5cb01bc82d3a349 263 PIRSF PIRSF021288 1 262 1.1E-144 T 28-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain A21D_RS17595 82910ac1bdfd086cb5cb01bc82d3a349 263 Gene3D G3DSA:3.30.70.260 3 243 7.0E-4 T 28-03-2018 A21D_RS17595 82910ac1bdfd086cb5cb01bc82d3a349 263 SUPERFAMILY SSF55021 5 73 1.42E-6 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Gene3D G3DSA:3.30.70.20 49 97 8.4E-4 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 SUPERFAMILY SSF54862 85 192 2.72E-66 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 SUPERFAMILY SSF54862 224 292 2.72E-66 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Gene3D G3DSA:3.30.70.20 154 199 4.5E-19 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Pfam PF16947 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding 20 70 3.5E-13 T 28-03-2018 IPR031604 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, N-terminal A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Gene3D G3DSA:3.30.70.20 98 153 9.8E-17 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Gene3D G3DSA:3.30.70.20 217 293 1.7E-22 T 28-03-2018 A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Pfam PF13247 4Fe-4S dicluster domain 137 191 3.3E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS14935 af339b73f6fee30c6aa577484cb1efff 293 Pfam PF13247 4Fe-4S dicluster domain 225 259 8.2E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 Gene3D G3DSA:1.10.760.10 59 158 2.9E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 SUPERFAMILY SSF46626 48 160 2.36E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 Gene3D G3DSA:1.10.760.10 159 266 4.5E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 85 152 1.2E-4 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 180 258 1.1E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS13835 01d84da77bff0a2e6eb0b2a992164c27 308 SUPERFAMILY SSF46626 175 267 2.87E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 189 199 2.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 375 391 2.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 205 221 2.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 252 269 2.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 234 247 2.2E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 PIRSF PIRSF039101 2 494 5.8E-200 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 Pfam PF01336 OB-fold nucleic acid binding domain 59 136 7.8E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 493 2.5E-222 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 Gene3D G3DSA:3.30.930.10 146 490 7.6E-105 T 28-03-2018 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 SUPERFAMILY SSF50249 4 145 2.79E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 SUPERFAMILY SSF55681 152 491 2.39E-119 T 28-03-2018 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 11 493 45.994 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 Gene3D G3DSA:2.40.50.140 5 145 2.1E-40 T 28-03-2018 A21D_RS06615 dddafd8ea0e087b46b76802a7acfd1d5 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 154 490 1.5E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS09665 b825a01beebc11e2b6e0c104f6be1465 214 SUPERFAMILY SSF141571 38 211 8.37E-37 T 28-03-2018 A21D_RS09665 b825a01beebc11e2b6e0c104f6be1465 214 Pfam PF13599 Pentapeptide repeats (9 copies) 89 165 9.5E-15 T 28-03-2018 IPR001646 Pentapeptide repeat A21D_RS09665 b825a01beebc11e2b6e0c104f6be1465 214 Gene3D G3DSA:2.160.10.20 36 130 6.3E-16 T 28-03-2018 A21D_RS09665 b825a01beebc11e2b6e0c104f6be1465 214 Gene3D G3DSA:2.160.10.20 131 203 1.8E-10 T 28-03-2018 A21D_RS16165 5818eae7856ec84be7045fc7825b3690 83 Pfam PF11118 Protein of unknown function (DUF2627) 3 73 8.3E-28 T 28-03-2018 IPR020138 Uncharacterised protein family YqzF A21D_RS18640 9beb058c85ea955522dbaf36ae6fc023 509 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 497 1.2E-199 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS18640 9beb058c85ea955522dbaf36ae6fc023 509 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 497 7.0E-172 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS08870 834ddb6fb735fb16f69586dc4c1fcdee 310 SUPERFAMILY SSF52540 4 224 1.27E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS08870 834ddb6fb735fb16f69586dc4c1fcdee 310 Pfam PF00005 ABC transporter 21 160 8.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS08870 834ddb6fb735fb16f69586dc4c1fcdee 310 Pfam PF13732 Domain of unknown function (DUF4162) 214 295 5.7E-10 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 A21D_RS08870 834ddb6fb735fb16f69586dc4c1fcdee 310 Gene3D G3DSA:3.40.50.300 1 258 2.3E-60 T 28-03-2018 A21D_RS08870 834ddb6fb735fb16f69586dc4c1fcdee 310 SMART SM00382 29 209 5.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09650 f1f052eea4312b652db3aabe20893f5b 199 Pfam PF14042 Domain of unknown function (DUF4247) 32 194 1.3E-15 T 28-03-2018 IPR025341 Protein of unknown function DUF4247 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 Gene3D G3DSA:3.30.420.40 251 315 1.5E-10 T 28-03-2018 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 Gene3D G3DSA:3.30.420.40 159 193 3.1E-4 T 28-03-2018 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 SUPERFAMILY SSF53067 148 328 9.26E-50 T 28-03-2018 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 Gene3D G3DSA:3.30.420.40 5 158 3.1E-32 T 28-03-2018 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 333 7.3E-149 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 Pfam PF06723 MreB/Mbl protein 8 332 1.4E-142 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 65 88 2.2E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 130 149 2.2E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 185 205 2.2E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 298 324 2.2E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 45 63 2.2E-54 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 SUPERFAMILY SSF53067 6 144 1.19E-36 T 28-03-2018 A21D_RS15180 16f73cfefb5fe47b418890188cd654f5 346 Gene3D G3DSA:3.90.640.10 194 250 1.0E-28 T 28-03-2018 A21D_RS19165 7c95830113c53afd692117c47e78cedd 377 Gene3D G3DSA:1.10.10.10 2 96 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS19165 7c95830113c53afd692117c47e78cedd 377 SMART SM00862 15 89 1.3E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS19165 7c95830113c53afd692117c47e78cedd 377 Pfam PF00486 Transcriptional regulatory protein, C terminal 15 89 1.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS19165 7c95830113c53afd692117c47e78cedd 377 SUPERFAMILY SSF46894 4 91 5.39E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 SMART SM00347 14 114 1.0E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 Gene3D G3DSA:1.10.10.10 1 98 7.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 Pfam PF01047 MarR family 21 79 9.4E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 124 3.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 70 3.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 3.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 PRINTS PR00598 Bacterial regulatory protein MarR family signature 38 54 3.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 Gene3D G3DSA:1.10.287.100 99 132 9.5E-4 T 28-03-2018 A21D_RS15030 bc61c232c11685c427d5d94bbe3daf8d 134 SUPERFAMILY SSF46785 2 130 3.26E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04950 17c701eec56ceafbff20f01d974a8c42 300 Pfam PF02361 Cobalt transport protein 50 271 4.0E-43 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A21D_RS01740 cc12a1308e9952ea57cd3bd5710f14fa 260 Pfam PF12730 ABC-2 family transporter protein 8 198 1.2E-21 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS11150 6cc69ea18cc32594979581843afc8063 120 SUPERFAMILY SSF46785 10 100 1.17E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11150 6cc69ea18cc32594979581843afc8063 120 Pfam PF03551 Transcriptional regulator PadR-like family 14 87 7.4E-28 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal A21D_RS11150 6cc69ea18cc32594979581843afc8063 120 TIGRFAM TIGR03433 padR_acidobact: transcriptional regulator, Acidobacterial, PadR-family 6 101 3.2E-30 T 28-03-2018 IPR017799 Transcription regulator PadR, acidobacterial-type A21D_RS11150 6cc69ea18cc32594979581843afc8063 120 Gene3D G3DSA:1.10.10.10 1 98 4.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06990 0ebae5e69dd73687ff8adbb61598f29f 399 Gene3D G3DSA:3.90.260.10 79 184 3.7E-6 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS06990 0ebae5e69dd73687ff8adbb61598f29f 399 Gene3D G3DSA:3.90.260.10 185 225 0.031 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS06990 0ebae5e69dd73687ff8adbb61598f29f 399 SUPERFAMILY SSF54001 67 223 6.32E-30 T 28-03-2018 A21D_RS06990 0ebae5e69dd73687ff8adbb61598f29f 399 SMART SM00460 148 208 1.3E-20 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS06990 0ebae5e69dd73687ff8adbb61598f29f 399 Pfam PF01841 Transglutaminase-like superfamily 107 205 6.3E-25 T 28-03-2018 IPR002931 Transglutaminase-like A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.1E-4 T 28-03-2018 A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 1.9E-71 T 28-03-2018 A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 7.0E-109 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.4E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 SUPERFAMILY SSF51735 4 246 1.58E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 Gene3D G3DSA:3.40.50.720 1 37 1.7E-9 T 28-03-2018 A21D_RS18105 47b25e98b65e0bc5425caed91cce9849 246 Gene3D G3DSA:3.40.50.720 38 246 3.2E-71 T 28-03-2018 A21D_RS09040 c96144e575c99c5ceb3bfee6f604e78d 300 SUPERFAMILY SSF52540 4 228 1.43E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09040 c96144e575c99c5ceb3bfee6f604e78d 300 Gene3D G3DSA:3.40.50.300 2 276 1.4E-57 T 28-03-2018 A21D_RS09040 c96144e575c99c5ceb3bfee6f604e78d 300 Pfam PF00005 ABC transporter 22 159 1.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09040 c96144e575c99c5ceb3bfee6f604e78d 300 SMART SM00382 30 206 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09040 c96144e575c99c5ceb3bfee6f604e78d 300 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 557 1.7E-226 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 Pfam PF00920 Dehydratase family 37 554 4.9E-215 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 SUPERFAMILY SSF52016 381 558 4.39E-54 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 SUPERFAMILY SSF143975 4 379 7.32E-144 T 28-03-2018 A21D_RS01455 57a1b83bf4f87eb363b5578b6b548eb4 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 7 557 45.949 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A21D_RS00580 956aed1954a617ff7f3ac29fd0cd2722 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 325 1.7E-98 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A21D_RS00580 956aed1954a617ff7f3ac29fd0cd2722 331 SUPERFAMILY SSF50891 193 307 1.33E-10 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS00580 956aed1954a617ff7f3ac29fd0cd2722 331 SMART SM00797 25 317 9.9E-132 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A21D_RS00580 956aed1954a617ff7f3ac29fd0cd2722 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 300 1.5E-92 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A21D_RS17520 349d772760e97c73cc18ed01e89e8269 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 30.32 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A21D_RS17520 349d772760e97c73cc18ed01e89e8269 74 SUPERFAMILY SSF50182 6 64 2.86E-24 T 28-03-2018 IPR010920 LSM domain A21D_RS17520 349d772760e97c73cc18ed01e89e8269 74 Gene3D G3DSA:2.30.30.100 4 74 1.2E-33 T 28-03-2018 A21D_RS17520 349d772760e97c73cc18ed01e89e8269 74 Pfam PF17209 Hfq protein 7 69 4.2E-33 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A21D_RS17520 349d772760e97c73cc18ed01e89e8269 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 4.6E-33 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A21D_RS15005 dffc11be85b85a99e7002d67a112f4ee 41 Pfam PF02416 mttA/Hcf106 family 1 37 5.7E-10 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A21D_RS06495 e4e7a245113d3a412e7fa44a6c78bb53 365 SMART SM00670 165 272 1.5E-13 T 28-03-2018 IPR002716 PIN domain A21D_RS06495 e4e7a245113d3a412e7fa44a6c78bb53 365 Pfam PF01938 TRAM domain 296 349 9.0E-5 T 28-03-2018 IPR002792 TRAM domain A21D_RS06495 e4e7a245113d3a412e7fa44a6c78bb53 365 Gene3D G3DSA:3.40.50.1010 160 296 5.9E-25 T 28-03-2018 IPR029060 PIN domain-like A21D_RS06495 e4e7a245113d3a412e7fa44a6c78bb53 365 SUPERFAMILY SSF88723 164 293 4.25E-24 T 28-03-2018 IPR029060 PIN domain-like A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 PRINTS PR00133 Glycosyl hydrolase family 3 signature 92 111 4.1E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 PRINTS PR00133 Glycosyl hydrolase family 3 signature 248 266 4.1E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 PRINTS PR00133 Glycosyl hydrolase family 3 signature 170 186 4.1E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 329 7.4E-100 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 Gene3D G3DSA:3.20.20.300 10 361 1.4E-96 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 SUPERFAMILY SSF51445 10 339 7.37E-97 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS02270 e212f46f61c040958f5627c99d81c5a3 530 Gene3D G3DSA:3.40.50.1700 362 530 8.1E-15 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 3.0E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 Pfam PF00072 Response regulator receiver domain 10 116 1.9E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 SMART SM00448 8 116 7.7E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 SMART SM00862 148 221 2.6E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 Gene3D G3DSA:1.10.10.10 122 224 1.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 Gene3D G3DSA:3.40.50.2300 1 121 1.2E-19 T 28-03-2018 A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 SUPERFAMILY SSF52172 8 125 6.4E-22 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS07770 dccb56ba6ea7c4c77f3e3019d71e9cea 224 SUPERFAMILY SSF46894 125 221 1.36E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS01860 08409d5268878138dbcd7d0d73bf442b 100 Gene3D G3DSA:3.30.70.100 1 100 4.9E-25 T 28-03-2018 A21D_RS01860 08409d5268878138dbcd7d0d73bf442b 100 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 99 4.0E-35 T 28-03-2018 IPR009799 EthD domain A21D_RS01860 08409d5268878138dbcd7d0d73bf442b 100 SUPERFAMILY SSF54909 1 99 3.38E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS01860 08409d5268878138dbcd7d0d73bf442b 100 Pfam PF07110 EthD domain 16 87 1.1E-9 T 28-03-2018 IPR009799 EthD domain A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 54 302 7.0E-73 T 28-03-2018 A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 SMART SM00062 51 292 0.0028 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 SUPERFAMILY SSF53850 48 292 1.63E-43 T 28-03-2018 A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 275 7.2E-77 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 Gene3D G3DSA:3.40.190.10 144 298 2.9E-30 T 28-03-2018 A21D_RS09925 5b7788fe1d8be5a897e45df0a0884dae 318 Gene3D G3DSA:3.40.190.10 50 143 3.2E-6 T 28-03-2018 A21D_RS07955 d940fefc7cfb582635cbfb932bdfcdad 475 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 6 475 7.3E-210 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 A21D_RS07955 d940fefc7cfb582635cbfb932bdfcdad 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 5 474 4.9E-191 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 A21D_RS07955 d940fefc7cfb582635cbfb932bdfcdad 475 Pfam PF13520 Amino acid permease 8 413 1.7E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS07955 d940fefc7cfb582635cbfb932bdfcdad 475 PIRSF PIRSF006060 1 454 3.2E-55 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS11115 40debe768123f4073e188c042df41391 477 Pfam PF13520 Amino acid permease 13 449 6.2E-49 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS11115 40debe768123f4073e188c042df41391 477 PIRSF PIRSF006060 1 475 6.6E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 656 3.9E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 660 689 2.9E-4 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 578 614 2.3E-16 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 SUPERFAMILY SSF56712 4 590 2.35E-203 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:1.10.460.10 452 564 3.0E-29 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:1.10.460.10 135 327 1.0E-50 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 295 304 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 474 488 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Pfam PF01131 DNA topoisomerase 128 548 2.3E-139 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:2.70.20.10 328 451 1.5E-41 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Pfam PF01751 Toprim domain 5 113 1.5E-29 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 SMART SM00437 242 511 9.4E-126 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:3.40.50.140 2 129 1.5E-39 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 SUPERFAMILY SSF57783 574 614 9.52E-15 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 SMART SM00436 104 192 1.7E-53 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 612 7.0E-267 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 SMART SM00493 3 103 2.3E-31 T 28-03-2018 IPR006171 TOPRIM domain A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 634 55.931 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:3.30.65.10 565 614 3.1E-18 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:3.30.65.10 615 653 7.0E-9 T 28-03-2018 A21D_RS17990 6899ecec2beae7c9d8131a4d20bb25f6 692 Gene3D G3DSA:3.30.65.10 654 692 7.0E-6 T 28-03-2018 A21D_RS02105 5540553cbf98f70036d870b11556b390 382 SUPERFAMILY SSF110738 5 379 5.23E-134 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A21D_RS02105 5540553cbf98f70036d870b11556b390 382 Gene3D G3DSA:3.90.1510.10 46 279 1.8E-94 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 A21D_RS02105 5540553cbf98f70036d870b11556b390 382 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 5 378 1.4E-158 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A21D_RS02105 5540553cbf98f70036d870b11556b390 382 Pfam PF02595 Glycerate kinase family 6 377 8.4E-148 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A21D_RS02105 5540553cbf98f70036d870b11556b390 382 PIRSF PIRSF006078 4 380 2.5E-133 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A21D_RS11375 30039942fa521f50d7165539a65387f7 183 Pfam PF00484 Carbonic anhydrase 37 179 3.4E-36 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS11375 30039942fa521f50d7165539a65387f7 183 SMART SM00947 29 183 8.7E-38 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS11375 30039942fa521f50d7165539a65387f7 183 Gene3D G3DSA:3.40.1050.10 2 183 1.8E-53 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS11375 30039942fa521f50d7165539a65387f7 183 SUPERFAMILY SSF53056 4 182 2.49E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS11375 30039942fa521f50d7165539a65387f7 183 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 41 48 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A21D_RS17865 7211a844799910233131f736c524b210 89 PIRSF PIRSF004669 1 89 7.7E-34 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A21D_RS17865 7211a844799910233131f736c524b210 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 9.4E-34 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 A21D_RS17865 7211a844799910233131f736c524b210 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.6E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A21D_RS17865 7211a844799910233131f736c524b210 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.6E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A21D_RS17865 7211a844799910233131f736c524b210 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.6E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A21D_RS17865 7211a844799910233131f736c524b210 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 4.9E-30 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 PIRSF PIRSF004848 1 222 7.1E-65 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 222 5.0E-50 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 Gene3D G3DSA:3.20.20.10 1 222 1.1E-54 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 SUPERFAMILY SSF51419 1 222 8.9E-71 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A21D_RS18340 e39aa101d0716433d1d53b838dc401ca 222 Pfam PF01168 Alanine racemase, N-terminal domain 6 222 4.0E-21 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS02460 ecfd3d5152ed1fd68b65a56b733cbae8 493 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 1.2E-150 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A21D_RS18620 5ecfb61c6177333dc63699e28ec3b5b5 210 Pfam PF06335 Protein of unknown function (DUF1054) 6 198 5.3E-75 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 A21D_RS18620 5ecfb61c6177333dc63699e28ec3b5b5 210 PIRSF PIRSF021332 1 204 1.4E-85 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 A21D_RS18620 5ecfb61c6177333dc63699e28ec3b5b5 210 SUPERFAMILY SSF142913 2 203 1.94E-75 T 28-03-2018 A21D_RS18620 5ecfb61c6177333dc63699e28ec3b5b5 210 Hamap MF_01851 UPF0637 protein . 5 200 38.065 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 A21D_RS05160 128ec2dff0a05e5b432c7a7ea3ff241e 199 Gene3D G3DSA:1.10.357.10 1 189 1.8E-11 T 28-03-2018 A21D_RS05160 128ec2dff0a05e5b432c7a7ea3ff241e 199 SUPERFAMILY SSF46689 4 71 3.28E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05160 128ec2dff0a05e5b432c7a7ea3ff241e 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 7.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04780 4563afeb31b7777b99c479d11e1476dc 535 Gene3D G3DSA:3.40.190.10 47 231 3.5E-30 T 28-03-2018 A21D_RS04780 4563afeb31b7777b99c479d11e1476dc 535 SUPERFAMILY SSF53850 19 532 2.06E-81 T 28-03-2018 A21D_RS04780 4563afeb31b7777b99c479d11e1476dc 535 Gene3D G3DSA:3.40.190.10 462 533 9.4E-11 T 28-03-2018 A21D_RS04780 4563afeb31b7777b99c479d11e1476dc 535 Pfam PF13416 Bacterial extracellular solute-binding protein 73 386 4.8E-14 T 28-03-2018 A21D_RS04780 4563afeb31b7777b99c479d11e1476dc 535 Gene3D G3DSA:3.40.190.10 268 423 0.006 T 28-03-2018 A21D_RS17920 caa6aacb472978c39e9055d52d988868 202 Gene3D G3DSA:3.80.10.10 15 140 1.4E-4 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A21D_RS17920 caa6aacb472978c39e9055d52d988868 202 SUPERFAMILY SSF158791 143 193 5.89E-7 T 28-03-2018 A21D_RS17920 caa6aacb472978c39e9055d52d988868 202 Pfam PF03448 MgtE intracellular N domain 144 192 3.7E-6 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A21D_RS17920 caa6aacb472978c39e9055d52d988868 202 Gene3D G3DSA:1.10.220.30 141 201 1.8E-7 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS14980 2fd7683115e0e8a42b3379556c55f3f7 146 SUPERFAMILY SSF54690 5 139 1.96E-46 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14980 2fd7683115e0e8a42b3379556c55f3f7 146 Pfam PF02391 MoaE protein 9 118 1.3E-35 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS14980 2fd7683115e0e8a42b3379556c55f3f7 146 Gene3D G3DSA:3.90.1170.40 1 144 1.8E-48 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A21D_RS06740 93250dca07c9b609f35a5d50dbadf81f 76 ProDom PD057826 YABK 5 76 6.0E-21 T 28-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A21D_RS06740 93250dca07c9b609f35a5d50dbadf81f 76 Pfam PF10955 Protein of unknown function (DUF2757) 3 76 3.9E-29 T 28-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 Pfam PF00491 Arginase family 4 294 2.0E-81 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PIRSF PIRSF036979 1 296 1.3E-38 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PRINTS PR00116 Arginase signature 119 146 7.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PRINTS PR00116 Arginase signature 173 191 7.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PRINTS PR00116 Arginase signature 257 271 7.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PRINTS PR00116 Arginase signature 222 251 7.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 PRINTS PR00116 Arginase signature 96 111 7.0E-45 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 ProSitePatterns PS01053 Arginase family signature. 225 246 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 SUPERFAMILY SSF52768 5 297 1.22E-96 T 28-03-2018 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 TIGRFAM TIGR01229 rocF_arginase: arginase 6 299 3.6E-107 T 28-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 A21D_RS05330 95dc9652e8290aa03b965e716c29215b 300 Gene3D G3DSA:3.40.800.10 1 297 1.0E-96 T 28-03-2018 A21D_RS16060 cac531dae7aea7f7888677ca1a337e47 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 4 65 6.7E-30 T 28-03-2018 IPR009570 Stage III sporulation protein AC A21D_RS16060 cac531dae7aea7f7888677ca1a337e47 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 2.0E-16 T 28-03-2018 IPR025664 Stage III sporulation protein AC/AD family A21D_RS01315 e15bc9e7d84dd8658317183ae551e3dd 300 SUPERFAMILY SSF161098 89 281 1.7E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01315 e15bc9e7d84dd8658317183ae551e3dd 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 292 3.1E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01315 e15bc9e7d84dd8658317183ae551e3dd 300 Gene3D G3DSA:1.10.3720.10 24 283 1.2E-33 T 28-03-2018 A21D_RS07015 f2f57919c44ba3662ba09eaedbaf16d4 363 Gene3D G3DSA:3.20.20.70 3 360 1.4E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS07015 f2f57919c44ba3662ba09eaedbaf16d4 363 SUPERFAMILY SSF51395 1 351 4.28E-97 T 28-03-2018 A21D_RS07015 f2f57919c44ba3662ba09eaedbaf16d4 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 341 2.4E-72 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A21D_RS11970 a6a16522cd1bc592184a1914a480f8c0 407 Pfam PF02810 SEC-C motif 389 407 4.4E-8 T 28-03-2018 IPR004027 SEC-C motif A21D_RS11970 a6a16522cd1bc592184a1914a480f8c0 407 SUPERFAMILY SSF103642 386 406 5.4E-7 T 28-03-2018 A21D_RS11970 a6a16522cd1bc592184a1914a480f8c0 407 Gene3D G3DSA:3.10.450.50 5 407 2.3E-15 T 28-03-2018 A21D_RS10780 abd08775987e102d35409168b71482d2 406 SUPERFAMILY SSF103190 263 403 2.98E-38 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A21D_RS10780 abd08775987e102d35409168b71482d2 406 Gene3D G3DSA:3.30.450.20 290 406 4.6E-13 T 28-03-2018 A21D_RS10780 abd08775987e102d35409168b71482d2 406 Pfam PF10388 EAL-domain associated signalling protein domain 240 406 1.7E-73 T 28-03-2018 IPR018842 YkuI, C-terminal A21D_RS10780 abd08775987e102d35409168b71482d2 406 Gene3D G3DSA:3.20.20.450 3 250 3.9E-29 T 28-03-2018 IPR001633 EAL domain A21D_RS10780 abd08775987e102d35409168b71482d2 406 Pfam PF00563 EAL domain 7 235 1.0E-25 T 28-03-2018 IPR001633 EAL domain A21D_RS10780 abd08775987e102d35409168b71482d2 406 Gene3D G3DSA:1.20.5.170 251 287 1.9E-12 T 28-03-2018 A21D_RS10780 abd08775987e102d35409168b71482d2 406 SUPERFAMILY SSF141868 2 248 1.7E-35 T 28-03-2018 IPR001633 EAL domain A21D_RS10780 abd08775987e102d35409168b71482d2 406 SMART SM00052 2 241 2.0E-9 T 28-03-2018 IPR001633 EAL domain A21D_RS06365 f41a722563bace86f961d1fb1930a706 95 Gene3D G3DSA:3.30.70.330 2 95 4.8E-33 T 28-03-2018 A21D_RS06365 f41a722563bace86f961d1fb1930a706 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 22.143 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A21D_RS06365 f41a722563bace86f961d1fb1930a706 95 SUPERFAMILY SSF54189 2 93 4.68E-33 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06365 f41a722563bace86f961d1fb1930a706 95 Pfam PF00276 Ribosomal protein L23 6 88 5.6E-34 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 SUPERFAMILY SSF53335 28 310 5.36E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 122 136 2.9E-5 T 28-03-2018 A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 217 241 2.9E-5 T 28-03-2018 A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 94 110 2.9E-5 T 28-03-2018 A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 PIRSF PIRSF026567 3 329 1.0E-123 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 Gene3D G3DSA:3.40.50.150 90 328 4.5E-35 T 28-03-2018 A21D_RS14450 6f19949910a2720e4ae4d58a0e708ff8 331 Pfam PF02384 N-6 DNA Methylase 97 292 5.2E-14 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 SUPERFAMILY SSF52172 1 131 2.13E-33 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 Gene3D G3DSA:1.10.10.10 162 234 6.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 Pfam PF00072 Response regulator receiver domain 4 115 1.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 PIRSF PIRSF006171 1 232 9.8E-72 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 Gene3D G3DSA:3.40.50.2300 1 144 4.4E-29 T 28-03-2018 A21D_RS13610 355257f2a1649c837cc9ad4770ec2293 240 SMART SM00448 2 115 5.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01160 e888b70d564ee63542898dcf8e950afb 255 Gene3D G3DSA:1.10.3720.10 4 255 2.8E-26 T 28-03-2018 A21D_RS01160 e888b70d564ee63542898dcf8e950afb 255 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 2 254 6.2E-77 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A21D_RS01160 e888b70d564ee63542898dcf8e950afb 255 SUPERFAMILY SSF161098 59 247 2.09E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01160 e888b70d564ee63542898dcf8e950afb 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 246 6.6E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS11680 63968bd0837b29c35be1007bd9243d78 296 Gene3D G3DSA:3.40.50.720 1 296 6.4E-35 T 28-03-2018 A21D_RS11680 63968bd0837b29c35be1007bd9243d78 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 4.0E-17 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A21D_RS11680 63968bd0837b29c35be1007bd9243d78 296 SUPERFAMILY SSF51735 1 269 2.82E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11680 63968bd0837b29c35be1007bd9243d78 296 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 290 5.9E-108 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 A21D_RS11680 63968bd0837b29c35be1007bd9243d78 296 Pfam PF08338 Domain of unknown function (DUF1731) 247 293 1.0E-14 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 A21D_RS18745 458f065a71a61fb1019ef04f96c4a869 284 Gene3D G3DSA:3.60.21.10 34 283 1.7E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS18745 458f065a71a61fb1019ef04f96c4a869 284 Pfam PF00149 Calcineurin-like phosphoesterase 55 219 4.1E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS18745 458f065a71a61fb1019ef04f96c4a869 284 SUPERFAMILY SSF56300 53 281 1.36E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS17135 4cb4c8ca0abbdcc4f6d7320d43020140 123 SUPERFAMILY SSF52172 1 120 4.27E-38 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS17135 4cb4c8ca0abbdcc4f6d7320d43020140 123 Gene3D G3DSA:3.40.50.2300 1 123 2.6E-37 T 28-03-2018 A21D_RS17135 4cb4c8ca0abbdcc4f6d7320d43020140 123 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17135 4cb4c8ca0abbdcc4f6d7320d43020140 123 SMART SM00448 2 114 5.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 SUPERFAMILY SSF47807 175 285 3.74E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 SMART SM00475 2 265 2.7E-116 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 Gene3D G3DSA:1.10.150.20 189 266 8.2E-30 T 28-03-2018 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 Gene3D G3DSA:3.40.50.1010 4 188 8.8E-63 T 28-03-2018 IPR029060 PIN domain-like A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 SMART SM00279 177 212 2.1E-18 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 SUPERFAMILY SSF88723 5 158 4.91E-47 T 28-03-2018 IPR029060 PIN domain-like A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 8.5E-50 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A21D_RS16995 1dc6af3c059f1ec1fa5ca945e9b05250 287 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 262 1.0E-29 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A21D_RS02980 7aec16b12983d9ca0a0dd1b9a229941c 220 SUPERFAMILY SSF161098 9 200 2.22E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02980 7aec16b12983d9ca0a0dd1b9a229941c 220 Gene3D G3DSA:1.10.3720.10 2 216 7.7E-40 T 28-03-2018 A21D_RS02980 7aec16b12983d9ca0a0dd1b9a229941c 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 107 4.6E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A21D_RS02980 7aec16b12983d9ca0a0dd1b9a229941c 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 203 1.1E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS19360 d88f1d09e3c9149c4c857ef77ca06d2a 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 317 2.6E-51 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 A21D_RS19360 d88f1d09e3c9149c4c857ef77ca06d2a 343 Gene3D G3DSA:3.40.190.10 150 330 3.8E-4 T 28-03-2018 A21D_RS16385 0faf240b7460d493e2cf6f23c8f2de10 121 Gene3D G3DSA:3.40.630.30 3 115 1.2E-12 T 28-03-2018 A21D_RS16385 0faf240b7460d493e2cf6f23c8f2de10 121 Pfam PF13673 Acetyltransferase (GNAT) domain 31 114 3.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS16385 0faf240b7460d493e2cf6f23c8f2de10 121 SUPERFAMILY SSF55729 20 114 1.89E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS05995 5c2b27a28b3b5ede12bc05c818fd6a64 265 Gene3D G3DSA:3.40.50.300 8 248 5.9E-56 T 28-03-2018 A21D_RS05995 5c2b27a28b3b5ede12bc05c818fd6a64 265 Pfam PF00005 ABC transporter 26 174 4.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05995 5c2b27a28b3b5ede12bc05c818fd6a64 265 SUPERFAMILY SSF52540 10 232 4.26E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05995 5c2b27a28b3b5ede12bc05c818fd6a64 265 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05995 5c2b27a28b3b5ede12bc05c818fd6a64 265 SMART SM00382 34 218 2.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 Gene3D G3DSA:3.40.50.300 1 333 4.5E-80 T 28-03-2018 A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 SUPERFAMILY SSF52540 32 317 6.88E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 3.4E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 SMART SM00382 33 241 2.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 Pfam PF00005 ABC transporter 25 183 3.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS04495 0cd14cbf77f69cb9b0ff4fbb261d3c82 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 5.1E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 SUPERFAMILY SSF52317 1 187 1.77E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 5.5E-13 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 5.5E-13 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 5.5E-13 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.4E-33 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 9.9E-9 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 9.9E-9 T 28-03-2018 A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 Pfam PF00117 Glutamine amidotransferase class-I 4 186 6.2E-52 T 28-03-2018 IPR017926 Glutamine amidotransferase A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 Gene3D G3DSA:3.40.50.880 1 189 2.8E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A21D_RS19205 d7ab1636f55ff6a207c38b6bc1ed135a 200 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 185 6.7E-70 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS12210 956e1b5a0bb779247d53c2f7665df0cd 466 Pfam PF00860 Permease family 26 401 8.1E-70 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS07140 2e75dbbb0a81c9de1ad5369c43b645f5 129 Pfam PF06271 RDD family 7 91 9.5E-6 T 28-03-2018 IPR010432 RDD A21D_RS03010 f3533d87e902abe98126df940d548c85 246 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 8 242 3.3E-60 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like A21D_RS03010 f3533d87e902abe98126df940d548c85 246 SUPERFAMILY SSF53474 13 230 2.17E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03010 f3533d87e902abe98126df940d548c85 246 Gene3D G3DSA:3.40.50.1820 8 242 3.5E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 PIRSF PIRSF036492 27 475 7.0E-86 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 SUPERFAMILY SSF53720 3 471 4.45E-152 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 Pfam PF00171 Aldehyde dehydrogenase family 13 470 8.2E-160 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 Gene3D G3DSA:3.40.309.10 261 456 1.7E-71 T 28-03-2018 A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS11300 5f10e0688ffd5cabffd656d1efa851d5 475 Gene3D G3DSA:3.40.605.10 1 260 6.1E-86 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS11670 e48cc7b85712dad5d330e34112806847 137 Gene3D G3DSA:1.10.3100.10 2 136 4.3E-22 T 28-03-2018 IPR027910 YdiL-like domain A21D_RS11670 e48cc7b85712dad5d330e34112806847 137 Pfam PF01381 Helix-turn-helix 9 63 1.2E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS11670 e48cc7b85712dad5d330e34112806847 137 SMART SM00530 8 63 2.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS11670 e48cc7b85712dad5d330e34112806847 137 SUPERFAMILY SSF47413 2 66 8.31E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS03315 dd07c630a8877a587328ff9e9a26a84e 437 Pfam PF12146 Serine aminopeptidase, S33 192 395 4.9E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A21D_RS03315 dd07c630a8877a587328ff9e9a26a84e 437 Gene3D G3DSA:3.40.50.1820 141 435 2.4E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03315 dd07c630a8877a587328ff9e9a26a84e 437 SUPERFAMILY SSF53474 140 289 2.34E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS03315 dd07c630a8877a587328ff9e9a26a84e 437 SUPERFAMILY SSF53474 319 432 2.34E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 Gene3D G3DSA:3.40.50.300 219 486 2.3E-47 T 28-03-2018 A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 Pfam PF00271 Helicase conserved C-terminal domain 228 335 2.0E-30 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 Gene3D G3DSA:3.40.50.300 11 218 9.8E-62 T 28-03-2018 A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 SUPERFAMILY SSF52540 70 356 1.58E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 Pfam PF00270 DEAD/DEAH box helicase 26 191 4.4E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 SMART SM00487 21 218 5.7E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 485 42.488 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 SMART SM00490 254 335 4.0E-36 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS09975 6b6a57c3d7535fbf90977c35ecefa697 487 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A21D_RS00705 f52b0f8704804f6fbb96ffd931cb6023 294 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 137 149 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A21D_RS00705 f52b0f8704804f6fbb96ffd931cb6023 294 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 261 6.8E-74 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A21D_RS00705 f52b0f8704804f6fbb96ffd931cb6023 294 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 259 7.8E-75 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A21D_RS00705 f52b0f8704804f6fbb96ffd931cb6023 294 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 264 17.54 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Gene3D G3DSA:3.20.190.10 2 133 1.3E-40 T 28-03-2018 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 43.123 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 SMART SM00898 2 118 1.5E-49 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Pfam PF06827 Zinc finger found in FPG and IleRS 247 275 5.1E-9 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 SUPERFAMILY SSF81624 2 139 1.3E-40 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Gene3D G3DSA:1.10.8.50 135 277 5.5E-48 T 28-03-2018 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 SUPERFAMILY SSF46946 134 223 9.16E-30 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 1.5E-33 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 3.0E-108 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 SMART SM01232 134 226 1.5E-46 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 SUPERFAMILY SSF57716 222 274 7.7E-16 T 28-03-2018 A21D_RS14610 ab184d401710322bd1099c3babad5693 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 1.7E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A21D_RS03485 75d8fec534f972404b143dcb035aa7ef 280 SUPERFAMILY SSF55166 89 216 5.49E-29 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS03485 75d8fec534f972404b143dcb035aa7ef 280 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 93 208 3.7E-31 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A21D_RS03485 75d8fec534f972404b143dcb035aa7ef 280 Gene3D G3DSA:3.30.1380.10 58 219 5.3E-29 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 PRINTS PR01011 Glutathione peroxidase family signature 121 130 3.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 PRINTS PR01011 Glutathione peroxidase family signature 21 38 3.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 PRINTS PR01011 Glutathione peroxidase family signature 56 72 3.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 PIRSF PIRSF000303 1 159 8.1E-72 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 Pfam PF00255 Glutathione peroxidase 3 109 1.2E-41 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 SUPERFAMILY SSF52833 1 157 2.25E-63 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS02900 221fc8d0093769d7f1c0cf3f4e21b678 159 Gene3D G3DSA:3.40.30.10 1 159 3.7E-52 T 28-03-2018 A21D_RS19395 de317ccb6c2101de5eb6657dda517240 158 SMART SM00903 10 150 2.0E-49 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A21D_RS19395 de317ccb6c2101de5eb6657dda517240 158 Pfam PF01613 Flavin reductase like domain 10 149 5.7E-34 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A21D_RS19395 de317ccb6c2101de5eb6657dda517240 158 Gene3D G3DSA:2.30.110.10 1 155 5.8E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A21D_RS19395 de317ccb6c2101de5eb6657dda517240 158 SUPERFAMILY SSF50475 1 150 6.87E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A21D_RS08255 5645c813f7978d4d5ff7900ca686a134 271 Pfam PF02811 PHP domain 4 169 7.4E-10 T 28-03-2018 IPR004013 PHP domain GO:0003824 A21D_RS08255 5645c813f7978d4d5ff7900ca686a134 271 SMART SM00481 3 68 2.6E-13 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A21D_RS08255 5645c813f7978d4d5ff7900ca686a134 271 Gene3D G3DSA:3.20.20.140 1 260 8.7E-41 T 28-03-2018 A21D_RS08255 5645c813f7978d4d5ff7900ca686a134 271 SUPERFAMILY SSF89550 167 253 2.16E-35 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS08255 5645c813f7978d4d5ff7900ca686a134 271 SUPERFAMILY SSF89550 1 83 2.16E-35 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A21D_RS19450 9a960bf9060d4a3543e3c9e8cd4746eb 615 SUPERFAMILY SSF53649 242 583 8.18E-59 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A21D_RS19450 9a960bf9060d4a3543e3c9e8cd4746eb 615 Pfam PF00884 Sulfatase 244 533 8.7E-34 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A21D_RS19450 9a960bf9060d4a3543e3c9e8cd4746eb 615 PIRSF PIRSF005091 1 615 3.4E-160 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like A21D_RS19450 9a960bf9060d4a3543e3c9e8cd4746eb 615 Gene3D G3DSA:3.40.720.10 239 543 1.3E-41 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A21D_RS07815 15cbb80f6b697275ba9c8c006cfe8384 255 Pfam PF10783 Protein of unknown function (DUF2599) 161 255 4.0E-17 T 28-03-2018 IPR019719 Protein of unknown function DUF2599 A21D_RS12675 06295e755d66ea13c49f46527bab66de 262 SUPERFAMILY SSF56219 1 262 1.57E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS12675 06295e755d66ea13c49f46527bab66de 262 Gene3D G3DSA:3.60.10.10 1 261 6.5E-36 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS12675 06295e755d66ea13c49f46527bab66de 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 19 253 4.6E-7 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A21D_RS15475 6737e5613449a8b7fc3c22c46404a7f3 75 Pfam PF04688 SPP1 phage holin 2 71 1.0E-25 T 28-03-2018 IPR006479 Holin A21D_RS15475 6737e5613449a8b7fc3c22c46404a7f3 75 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 3 73 2.3E-19 T 28-03-2018 IPR006479 Holin A21D_RS15475 6737e5613449a8b7fc3c22c46404a7f3 75 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 2 74 6.0E-10 T 28-03-2018 IPR006479 Holin A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 Pfam PF00367 phosphotransferase system, EIIB 470 500 2.7E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 4 541 1.4E-270 T 28-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 438 526 7.7E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 Gene3D G3DSA:3.30.1360.60 464 540 1.7E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 SUPERFAMILY SSF55604 468 540 1.57E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 479 496 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS12670 759bd0372cb8ee7a8875da0e4338d32d 544 Pfam PF02378 Phosphotransferase system, EIIC 14 377 8.8E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS09455 4f1b363ce90ac0ca374eda0773dd9231 151 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 98 1.5E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A21D_RS09455 4f1b363ce90ac0ca374eda0773dd9231 151 SUPERFAMILY SSF53927 3 142 2.85E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS09455 4f1b363ce90ac0ca374eda0773dd9231 151 Gene3D G3DSA:3.40.140.10 1 151 1.2E-32 T 28-03-2018 A21D_RS09455 4f1b363ce90ac0ca374eda0773dd9231 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 87 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 SUPERFAMILY SSF51569 30 355 6.69E-104 T 28-03-2018 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 93 349 3.0E-122 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 Gene3D G3DSA:3.20.20.70 96 355 1.0E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 Pfam PF00793 DAHP synthetase I family 109 355 2.0E-83 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 TIGRFAM TIGR01801 CM_A: chorismate mutase 3 100 4.0E-40 T 28-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 Pfam PF01817 Chorismate mutase type II 8 85 1.3E-19 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 SMART SM00830 8 87 2.1E-23 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS14340 7f5cd9db78bbcfa2f89537c90d90b8b9 356 Gene3D G3DSA:1.20.59.10 1 95 2.2E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 SUPERFAMILY SSF50129 1 148 1.26E-42 T 28-03-2018 IPR011032 GroES-like A21D_RS12735 fc02d08591374c56a09284146693dff1 311 SUPERFAMILY SSF51735 117 273 1.31E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS12735 fc02d08591374c56a09284146693dff1 311 Gene3D G3DSA:3.90.180.10 1 157 6.5E-57 T 28-03-2018 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 SMART SM00829 10 308 7.7E-26 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 Pfam PF13602 Zinc-binding dehydrogenase 187 308 2.0E-27 T 28-03-2018 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 Gene3D G3DSA:3.90.180.10 231 311 9.0E-5 T 28-03-2018 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 95 1.7E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A21D_RS12735 fc02d08591374c56a09284146693dff1 311 Gene3D G3DSA:3.40.50.720 158 230 6.3E-13 T 28-03-2018 A21D_RS01685 717a38f6dc0635f73df8bc0f07b0c073 84 Pfam PF05154 TM2 domain 1 48 6.2E-12 T 28-03-2018 IPR007829 TM2 domain A21D_RS04525 c25c283093c72fb74c76650d523ec224 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 9 75 7.6E-19 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 A21D_RS04525 c25c283093c72fb74c76650d523ec224 76 Pfam PF06612 Protein of unknown function (DUF1146) 17 63 9.6E-16 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 A21D_RS16940 b75e145891ab743f0ba064fd9be9dd75 165 Gene3D G3DSA:3.40.630.30 2 165 1.6E-26 T 28-03-2018 A21D_RS16940 b75e145891ab743f0ba064fd9be9dd75 165 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 4.0E-23 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS16940 b75e145891ab743f0ba064fd9be9dd75 165 SUPERFAMILY SSF55729 3 164 1.13E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 Gene3D G3DSA:1.20.5.110 74 98 8.1E-4 T 28-03-2018 A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 Gene3D G3DSA:1.10.287.540 134 174 0.0021 T 28-03-2018 A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 Gene3D G3DSA:1.20.5.110 2 36 0.021 T 28-03-2018 A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 Gene3D G3DSA:1.20.5.320 99 133 0.0099 T 28-03-2018 A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 SUPERFAMILY SSF57997 12 173 5.01E-16 T 28-03-2018 A21D_RS04125 b91e8c4e41a2027be7607dd30599064b 178 Gene3D G3DSA:1.20.1270.70 37 73 2.1E-19 T 28-03-2018 A21D_RS17160 bd7fcf8bd3cacd164faddd5514cb551a 465 Pfam PF05598 Transposase domain (DUF772) 62 129 7.3E-17 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS17160 bd7fcf8bd3cacd164faddd5514cb551a 465 Pfam PF13751 Transposase DDE domain 322 447 1.1E-30 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 Gene3D G3DSA:1.20.120.140 21 112 3.6E-21 T 28-03-2018 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 Gene3D G3DSA:3.40.50.300 116 326 4.0E-43 T 28-03-2018 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 SUPERFAMILY SSF52540 125 323 3.83E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 SUPERFAMILY SSF47364 22 99 3.27E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 SMART SM00962 124 325 1.8E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 298 311 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 SMART SM00963 25 106 1.9E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 SMART SM00382 123 301 2.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 Pfam PF00448 SRP54-type protein, GTPase domain 125 324 7.7E-80 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 49 324 1.5E-115 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 Pfam PF02881 SRP54-type protein, helical bundle domain 36 102 9.3E-14 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A21D_RS18080 c15979e1dcc49572575cc883bba7a43b 331 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 49 325 63.808 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 Gene3D G3DSA:3.40.50.300 4 194 6.9E-27 T 28-03-2018 A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 Pfam PF13476 AAA domain 5 216 2.9E-31 T 28-03-2018 A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 Pfam PF13558 Putative exonuclease SbcCD, C subunit 925 987 1.8E-13 T 28-03-2018 A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 Gene3D G3DSA:3.40.50.300 758 1019 2.0E-15 T 28-03-2018 A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 SUPERFAMILY SSF52540 328 362 1.57E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 SUPERFAMILY SSF52540 26 191 1.57E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18960 13b1304f237fe860655e2f8e2f7f2851 1030 SUPERFAMILY SSF52540 921 1015 1.57E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 SUPERFAMILY SSF56553 50 171 4.06E-44 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 302 3.0E-21 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 312 3.1E-121 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 1.3E-21 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 36.739 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 SUPERFAMILY SSF55257 146 230 2.75E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 SUPERFAMILY SSF55257 5 54 2.75E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 152 9.6E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 SMART SM00662 20 227 1.8E-100 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 1.1E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Gene3D G3DSA:3.30.1360.10 112 224 4.9E-26 T 28-03-2018 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Gene3D G3DSA:3.30.1360.10 1 111 9.4E-19 T 28-03-2018 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 SUPERFAMILY SSF47789 248 312 7.06E-24 T 28-03-2018 A21D_RS06240 6d806dc8636f00378ceec4b0db67e3c5 314 Gene3D G3DSA:1.10.150.20 241 314 7.4E-26 T 28-03-2018 A21D_RS10900 91ae264d44615d3aae5f787afc0f0e65 174 Gene3D G3DSA:3.30.1060.10 1 172 1.0E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS10900 91ae264d44615d3aae5f787afc0f0e65 174 Pfam PF01625 Peptide methionine sulfoxide reductase 7 157 2.8E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS10900 91ae264d44615d3aae5f787afc0f0e65 174 SUPERFAMILY SSF55068 3 168 2.22E-70 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS10900 91ae264d44615d3aae5f787afc0f0e65 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 4 163 35.613 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS10900 91ae264d44615d3aae5f787afc0f0e65 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 156 6.5E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A21D_RS01515 5a06b032fb54711b48fa2ea48ea7df2f 168 SUPERFAMILY SSF55729 1 160 6.97E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS01515 5a06b032fb54711b48fa2ea48ea7df2f 168 Gene3D G3DSA:3.40.630.30 1 164 1.6E-24 T 28-03-2018 A21D_RS01515 5a06b032fb54711b48fa2ea48ea7df2f 168 Pfam PF08445 FR47-like protein 80 143 2.7E-12 T 28-03-2018 IPR013653 FR47-like GO:0016747 A21D_RS19175 5d1597469943f56b3f27e28e43e518f0 252 Gene3D G3DSA:2.60.40.10 31 134 2.2E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS19175 5d1597469943f56b3f27e28e43e518f0 252 Gene3D G3DSA:2.60.40.10 158 252 2.2E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS19175 5d1597469943f56b3f27e28e43e518f0 252 Pfam PF13115 YtkA-like 35 115 4.0E-13 T 28-03-2018 IPR032693 YtkA-like domain A21D_RS19175 5d1597469943f56b3f27e28e43e518f0 252 Pfam PF13115 YtkA-like 155 233 5.0E-12 T 28-03-2018 IPR032693 YtkA-like domain A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 Gene3D G3DSA:3.40.50.620 2 138 1.8E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 PRINTS PR01438 Universal stress protein signature 98 110 1.1E-18 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-18 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 PRINTS PR01438 Universal stress protein signature 116 138 1.1E-18 T 28-03-2018 IPR006015 Universal stress protein A A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 SUPERFAMILY SSF52402 2 138 1.34E-33 T 28-03-2018 A21D_RS01600 7dfb691554bc04dce718b2eea2b0350d 138 Pfam PF00582 Universal stress protein family 2 138 5.3E-32 T 28-03-2018 IPR006016 UspA GO:0006950 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 2 74 29.394 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 Gene3D G3DSA:2.60.40.50 9 74 1.5E-39 T 28-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 Pfam PF02081 Tryptophan RNA-binding attenuator protein 7 74 5.2E-40 T 28-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 43 59 2.5E-34 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 59 74 2.5E-34 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 10 27 2.5E-34 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 27 43 2.5E-34 T 28-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A21D_RS16585 af444565f43c0cecbbb1801b9a83e42d 74 SUPERFAMILY SSF51219 8 74 4.71E-35 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A21D_RS02835 863cc9a84592cca7b22f7b0796457625 156 Pfam PF06114 IrrE N-terminal-like domain 44 142 5.5E-11 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A21D_RS09015 9667f5afaeacc873c1d5dcfad6506463 81 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 5 74 1.0E-19 T 28-03-2018 A21D_RS09015 9667f5afaeacc873c1d5dcfad6506463 81 Pfam PF07293 Protein of unknown function (DUF1450) 4 76 5.9E-24 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 A21D_RS10745 de3eac9627d5eff9700383be7b98e117 272 SUPERFAMILY SSF53448 1 264 2.14E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS10745 de3eac9627d5eff9700383be7b98e117 272 Pfam PF01501 Glycosyl transferase family 8 2 249 1.7E-36 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 A21D_RS10745 de3eac9627d5eff9700383be7b98e117 272 Gene3D G3DSA:3.90.550.10 1 268 2.1E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A21D_RS05850 ba564bcd79da33518d68b399161b0307 214 Pfam PF05031 Iron Transport-associated domain 31 141 2.1E-34 T 28-03-2018 IPR006635 NEAT domain A21D_RS05850 ba564bcd79da33518d68b399161b0307 214 SUPERFAMILY SSF158911 21 148 1.44E-37 T 28-03-2018 A21D_RS05850 ba564bcd79da33518d68b399161b0307 214 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 6 209 5.3E-47 T 28-03-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 A21D_RS05850 ba564bcd79da33518d68b399161b0307 214 SMART SM00725 32 147 5.4E-39 T 28-03-2018 IPR006635 NEAT domain A21D_RS06025 754be555262fff1d5e7f0870a1f2ee6b 250 Gene3D G3DSA:3.40.50.300 1 233 5.2E-52 T 28-03-2018 A21D_RS06025 754be555262fff1d5e7f0870a1f2ee6b 250 Pfam PF00005 ABC transporter 20 164 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06025 754be555262fff1d5e7f0870a1f2ee6b 250 SMART SM00382 26 213 3.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06025 754be555262fff1d5e7f0870a1f2ee6b 250 SUPERFAMILY SSF52540 2 226 2.24E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 Gene3D G3DSA:3.30.70.20 44 78 1.2E-8 T 28-03-2018 A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 Pfam PF12800 4Fe-4S binding domain 7 23 0.71 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 Pfam PF00037 4Fe-4S binding domain 34 56 8.5E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 SUPERFAMILY SSF54862 1 71 8.16E-19 T 28-03-2018 A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 Gene3D G3DSA:3.30.70.20 2 43 4.9E-14 T 28-03-2018 A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.6E-11 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.6E-11 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS01190 8fe642eb2a0f8be58b2be9ffdb4d2f35 79 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.6E-11 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 A21D_RS15505 4ba1a3540e01872e4fda64c386d4f3df 103 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 41 93 7.7E-16 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A21D_RS15505 4ba1a3540e01872e4fda64c386d4f3df 103 PIRSF PIRSF028784 8 102 6.4E-29 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A21D_RS15795 30721bfe19d9eb78a20a3421a775e321 94 ProDom PD060869 YQFT IG BH1387 5 73 3.0E-14 T 28-03-2018 IPR020277 Protein of unknown function DUF2624 A21D_RS15795 30721bfe19d9eb78a20a3421a775e321 94 Pfam PF11116 Protein of unknown function (DUF2624) 3 84 4.3E-29 T 28-03-2018 IPR020277 Protein of unknown function DUF2624 A21D_RS15795 30721bfe19d9eb78a20a3421a775e321 94 Gene3D G3DSA:3.40.190.10 6 92 7.4E-4 T 28-03-2018 A21D_RS00730 71341fcba75bc4369233777637e03657 117 Gene3D G3DSA:2.70.180.10 1 115 2.8E-51 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 A21D_RS00730 71341fcba75bc4369233777637e03657 117 Pfam PF08830 Protein of unknown function (DUF1806) 3 115 1.0E-50 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 A21D_RS00730 71341fcba75bc4369233777637e03657 117 SUPERFAMILY SSF89442 1 116 2.48E-51 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 A21D_RS19135 d4f3a2fdada755e03d9a43d2970936f9 312 SUPERFAMILY SSF161098 73 300 3.27E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS19135 d4f3a2fdada755e03d9a43d2970936f9 312 Gene3D G3DSA:1.20.58.370 14 62 2.9E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A21D_RS19135 d4f3a2fdada755e03d9a43d2970936f9 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 305 5.8E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS19135 d4f3a2fdada755e03d9a43d2970936f9 312 Gene3D G3DSA:1.10.3720.10 80 310 1.1E-48 T 28-03-2018 A21D_RS09435 ca54a0b7ed80acbda343d145c82bea8d 386 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A21D_RS09435 ca54a0b7ed80acbda343d145c82bea8d 386 Pfam PF01098 Cell cycle protein 12 376 2.4E-99 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A21D_RS09435 ca54a0b7ed80acbda343d145c82bea8d 386 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 9 375 8.5E-106 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 A21D_RS14430 79210e58197f3b2e1d7210cb324859e7 265 Gene3D G3DSA:2.60.200.30 118 243 7.5E-26 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS14430 79210e58197f3b2e1d7210cb324859e7 265 SUPERFAMILY SSF111331 16 264 6.02E-57 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A21D_RS14430 79210e58197f3b2e1d7210cb324859e7 265 Gene3D G3DSA:3.40.50.10330 9 117 5.5E-14 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A21D_RS14430 79210e58197f3b2e1d7210cb324859e7 265 Pfam PF01513 ATP-NAD kinase 39 250 1.4E-17 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS14430 79210e58197f3b2e1d7210cb324859e7 265 Hamap MF_00361 NAD kinase [nadK]. 2 265 20.423 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A21D_RS05020 1e06fd0a945b2e42fd72f06cb17e5045 137 Pfam PF13673 Acetyltransferase (GNAT) domain 34 126 1.4E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS05020 1e06fd0a945b2e42fd72f06cb17e5045 137 SUPERFAMILY SSF55729 9 125 5.06E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS05020 1e06fd0a945b2e42fd72f06cb17e5045 137 Gene3D G3DSA:3.40.630.30 4 129 4.6E-20 T 28-03-2018 A21D_RS10670 4a514b7bba236e896d7bb92c118d536c 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 29.628 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 A21D_RS10670 4a514b7bba236e896d7bb92c118d536c 131 Pfam PF05025 RbsD / FucU transport protein family 2 130 1.6E-42 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A21D_RS10670 4a514b7bba236e896d7bb92c118d536c 131 Gene3D G3DSA:3.40.1650.10 2 131 7.8E-35 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A21D_RS10670 4a514b7bba236e896d7bb92c118d536c 131 SUPERFAMILY SSF102546 2 131 9.81E-41 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 A21D_RS08275 7a878e6b9887c85ec14204036677bbba 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 283 3.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08275 7a878e6b9887c85ec14204036677bbba 285 Gene3D G3DSA:1.10.3720.10 20 272 7.1E-23 T 28-03-2018 A21D_RS08275 7a878e6b9887c85ec14204036677bbba 285 SUPERFAMILY SSF161098 84 269 5.36E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02760 a3352a4b15118a688e033fd1adf7f56c 133 Gene3D G3DSA:2.60.120.460 1 131 2.0E-45 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS02760 a3352a4b15118a688e033fd1adf7f56c 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 128 3.2E-37 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS02760 a3352a4b15118a688e033fd1adf7f56c 133 SUPERFAMILY SSF111038 3 131 4.32E-44 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS02760 a3352a4b15118a688e033fd1adf7f56c 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 130 3.8E-45 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS02760 a3352a4b15118a688e033fd1adf7f56c 133 PIRSF PIRSF004681 1 133 3.7E-38 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 A21D_RS13540 ba25aa20941b51ee90e43b26a345d518 152 Pfam PF10612 Spore coat protein Z 1 146 2.3E-47 T 28-03-2018 IPR019593 Spore coat protein Z/Y A21D_RS09960 e687ae4c073db2611a1c17ebcfe0ca43 236 Pfam PF12697 Alpha/beta hydrolase family 5 110 6.9E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A21D_RS09960 e687ae4c073db2611a1c17ebcfe0ca43 236 SUPERFAMILY SSF53474 5 228 3.89E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS09960 e687ae4c073db2611a1c17ebcfe0ca43 236 PIRSF PIRSF017388 1 231 6.7E-64 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 A21D_RS09960 e687ae4c073db2611a1c17ebcfe0ca43 236 Gene3D G3DSA:3.40.50.1820 3 230 3.2E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS13320 bc198c261743fb4c6045077339e27653 70 Pfam PF10676 Spore germination protein gerPA/gerPF 1 66 3.1E-22 T 28-03-2018 IPR019618 Spore germination protein GerPA/GerPF A21D_RS01045 dd796e12b11bfda0df7ba92fbf8b1193 351 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 3 346 3.0E-96 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A21D_RS01045 dd796e12b11bfda0df7ba92fbf8b1193 351 ProSitePatterns PS00869 Renal dipeptidase active site. 132 154 - T 28-03-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A21D_RS01045 dd796e12b11bfda0df7ba92fbf8b1193 351 Gene3D G3DSA:3.20.20.140 1 272 1.2E-72 T 28-03-2018 A21D_RS01045 dd796e12b11bfda0df7ba92fbf8b1193 351 Gene3D G3DSA:3.20.20.140 273 351 1.0E-23 T 28-03-2018 A21D_RS01045 dd796e12b11bfda0df7ba92fbf8b1193 351 SUPERFAMILY SSF51556 1 350 2.23E-85 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS09310 6925a748221f2c238971e1707659db79 430 Pfam PF10797 Protein of unknown function 4 425 1.9E-169 T 28-03-2018 IPR019733 Uncharacterised protein family YhfT A21D_RS03075 4b1da2fbbf981cb501b22249bfc59cbe 251 Pfam PF00005 ABC transporter 18 164 7.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03075 4b1da2fbbf981cb501b22249bfc59cbe 251 SMART SM00382 26 213 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03075 4b1da2fbbf981cb501b22249bfc59cbe 251 Gene3D G3DSA:3.40.50.300 1 228 2.0E-59 T 28-03-2018 A21D_RS03075 4b1da2fbbf981cb501b22249bfc59cbe 251 SUPERFAMILY SSF52540 2 227 3.7E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01420 e690c012d796d010935dd308eb70e861 192 Pfam PF00694 Aconitase C-terminal domain 5 123 5.2E-36 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS01420 e690c012d796d010935dd308eb70e861 192 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 185 3.4E-77 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A21D_RS01420 e690c012d796d010935dd308eb70e861 192 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 192 38.958 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A21D_RS01420 e690c012d796d010935dd308eb70e861 192 Gene3D G3DSA:3.20.19.10 1 173 1.2E-45 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A21D_RS01420 e690c012d796d010935dd308eb70e861 192 SUPERFAMILY SSF52016 4 189 1.45E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 Pfam PF09334 tRNA synthetases class I (M) 5 392 3.0E-79 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 Gene3D G3DSA:3.40.50.620 2 285 1.2E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 SUPERFAMILY SSF52374 174 379 1.63E-64 T 28-03-2018 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 SUPERFAMILY SSF52374 4 140 1.63E-64 T 28-03-2018 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 Gene3D G3DSA:1.10.730.10 315 539 2.0E-20 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 SUPERFAMILY SSF57770 141 174 5.23E-6 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A21D_RS02410 e5d55e8c24d92b363ace29f39d7018e0 541 SUPERFAMILY SSF47323 385 514 4.58E-8 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS12920 258dd27aa25c5a35df8a7890f6f99512 206 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 202 8.0E-23 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A21D_RS12920 258dd27aa25c5a35df8a7890f6f99512 206 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 6 203 1.5E-35 T 28-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ A21D_RS12920 258dd27aa25c5a35df8a7890f6f99512 206 Gene3D G3DSA:3.40.190.10 1 199 1.8E-4 T 28-03-2018 A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 SUPERFAMILY SSF51445 28 381 2.06E-63 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 SUPERFAMILY SSF51011 379 450 9.77E-8 T 28-03-2018 A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 Gene3D G3DSA:2.60.40.1180 375 461 1.5E-12 T 28-03-2018 A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 SMART SM00642 36 370 2.8E-24 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 Pfam PF00128 Alpha amylase, catalytic domain 64 341 7.1E-36 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A21D_RS13345 f6ee68bc6e8cc98ae2633f7ce83a9448 494 Gene3D G3DSA:3.20.20.80 23 374 4.7E-64 T 28-03-2018 A21D_RS12980 256e3af99282ae0246d849424877591f 242 Pfam PF13411 MerR HTH family regulatory protein 5 70 3.4E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 Gene3D G3DSA:1.10.1660.10 61 129 7.6E-4 T 28-03-2018 A21D_RS12980 256e3af99282ae0246d849424877591f 242 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 SMART SM00422 5 74 1.2E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 9.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 9.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 9.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12980 256e3af99282ae0246d849424877591f 242 Gene3D G3DSA:1.10.1660.10 1 60 3.0E-19 T 28-03-2018 A21D_RS12980 256e3af99282ae0246d849424877591f 242 SUPERFAMILY SSF46955 5 108 2.6E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS01580 e1f21b0df3674dff622276012a424e70 50 Pfam PF08179 Small acid-soluble spore protein P family 1 46 3.0E-16 T 28-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 A21D_RS01580 e1f21b0df3674dff622276012a424e70 50 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 50 15.408 T 28-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 A21D_RS05665 69f8f5e14e94a310dc8be1cbf06d6e39 146 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 90 2.2E-16 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 A21D_RS05665 69f8f5e14e94a310dc8be1cbf06d6e39 146 Gene3D G3DSA:1.10.287.950 28 112 2.5E-4 T 28-03-2018 A21D_RS13525 65e121eb5c844e9b018be308e5ec794d 248 SUPERFAMILY SSF56300 1 220 1.06E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS13525 65e121eb5c844e9b018be308e5ec794d 248 PRINTS PR00114 Serine/threonine phosphatase family signature 2 29 3.6E-9 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS13525 65e121eb5c844e9b018be308e5ec794d 248 PRINTS PR00114 Serine/threonine phosphatase family signature 40 67 3.6E-9 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS13525 65e121eb5c844e9b018be308e5ec794d 248 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 1.7E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS13525 65e121eb5c844e9b018be308e5ec794d 248 Gene3D G3DSA:3.60.21.10 1 248 6.7E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 3 119 1.5E-23 T 28-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 SUPERFAMILY SSF51735 144 245 9.48E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 145 239 6.6E-8 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 Gene3D G3DSA:3.40.50.720 151 289 9.6E-18 T 28-03-2018 A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 Gene3D G3DSA:3.40.50.720 3 150 8.4E-4 T 28-03-2018 A21D_RS18955 9eee2ef243c2910194afc9093f8f53ea 292 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 3 285 1.3E-108 T 28-03-2018 IPR014215 Dipicolinic acid synthetase subunit A A21D_RS00105 d9f564deaeaa57063b8631c709cbb8b2 100 SUPERFAMILY SSF101386 6 91 1.18E-15 T 28-03-2018 A21D_RS00105 d9f564deaeaa57063b8631c709cbb8b2 100 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 92 1.7E-7 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A21D_RS00105 d9f564deaeaa57063b8631c709cbb8b2 100 Gene3D G3DSA:1.10.287.1080 2 100 2.1E-21 T 28-03-2018 A21D_RS01365 2214a43b7e5fb3a450d0d7955eb551c3 301 Gene3D G3DSA:3.30.420.40 1 144 7.5E-34 T 28-03-2018 A21D_RS01365 2214a43b7e5fb3a450d0d7955eb551c3 301 Pfam PF00480 ROK family 5 293 9.2E-50 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A21D_RS01365 2214a43b7e5fb3a450d0d7955eb551c3 301 SUPERFAMILY SSF53067 1 299 5.93E-50 T 28-03-2018 A21D_RS01365 2214a43b7e5fb3a450d0d7955eb551c3 301 Gene3D G3DSA:3.30.420.40 145 280 2.2E-24 T 28-03-2018 A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 9 222 2.2E-66 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 Gene3D G3DSA:3.30.1360.40 9 102 5.3E-15 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 SMART SM00796 8 222 1.9E-84 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 SUPERFAMILY SSF50891 108 238 3.6E-45 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 SUPERFAMILY SSF160467 9 112 5.23E-13 T 28-03-2018 A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 Gene3D G3DSA:2.40.100.10 106 240 2.1E-47 T 28-03-2018 IPR029000 Cyclophilin-like domain A21D_RS00585 d58fd9670920a5d6adc08b9819031c93 249 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 14 231 6.9E-70 T 28-03-2018 IPR010016 KipI family A21D_RS00985 ea519ab6e3c0aec265935cc6cc9901de 549 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 483 499 - T 28-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 A21D_RS00985 ea519ab6e3c0aec265935cc6cc9901de 549 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 80 530 1.3E-95 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A21D_RS00985 ea519ab6e3c0aec265935cc6cc9901de 549 Pfam PF00939 Sodium:sulfate symporter transmembrane region 69 530 2.3E-95 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A21D_RS00550 4270ca841934a0a0c558d2c446229898 135 Pfam PF00075 RNase H 3 126 8.0E-15 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A21D_RS00550 4270ca841934a0a0c558d2c446229898 135 Gene3D G3DSA:3.30.420.10 1 135 3.1E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS00550 4270ca841934a0a0c558d2c446229898 135 SUPERFAMILY SSF53098 1 129 9.23E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 368 379 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 SUPERFAMILY SSF46548 350 397 4.36E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 SUPERFAMILY SSF46548 266 317 4.36E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 SUPERFAMILY SSF103501 12 240 8.5E-15 T 28-03-2018 IPR023234 NarG-like domain A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 Pfam PF02754 Cysteine-rich domain 579 665 1.3E-17 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 Pfam PF02754 Cysteine-rich domain 463 534 1.5E-5 T 28-03-2018 IPR004017 Cysteine-rich domain A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 281 292 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 Gene3D G3DSA:1.10.1060.10 248 401 7.4E-31 T 28-03-2018 A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 Pfam PF13183 4Fe-4S dicluster domain 278 382 2.0E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A21D_RS04735 932fcd9e37c8ac794ffb41e81b42b1bd 700 Gene3D G3DSA:1.20.950.20 4 236 1.6E-45 T 28-03-2018 A21D_RS18010 180fe4182516087ef7ee14e5ce09c801 87 Pfam PF01312 FlhB HrpN YscU SpaS Family 10 80 1.3E-18 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A21D_RS18010 180fe4182516087ef7ee14e5ce09c801 87 Gene3D G3DSA:3.40.1690.10 5 84 3.3E-27 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A21D_RS18010 180fe4182516087ef7ee14e5ce09c801 87 SUPERFAMILY SSF160544 8 84 6.8E-23 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 11 33 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 254 271 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 74 92 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 358 381 1.7E-9 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 SUPERFAMILY SSF103473 6 391 4.97E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 Gene3D G3DSA:1.20.1250.20 203 394 6.6E-21 T 28-03-2018 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 Gene3D G3DSA:1.20.1250.20 2 186 9.5E-21 T 28-03-2018 A21D_RS13785 f77c874cd8047943a098bf6595f8ef07 395 Pfam PF07690 Major Facilitator Superfamily 12 352 4.4E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.154 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 Gene3D G3DSA:3.90.470.10 1 113 1.4E-44 T 28-03-2018 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 SUPERFAMILY SSF54843 1 112 2.09E-44 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 6.9E-49 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06350 531b6cb28749af2f780be76052067ab1 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 108 7.9E-38 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A21D_RS19240 9dd3a091bb2add012e2eb8643535a251 437 Pfam PF06792 Uncharacterised protein family (UPF0261) 32 429 2.8E-165 T 28-03-2018 IPR008322 Uncharacterised protein family UPF0261 A21D_RS19240 9dd3a091bb2add012e2eb8643535a251 437 Gene3D G3DSA:1.10.150.20 245 436 0.012 T 28-03-2018 A21D_RS19240 9dd3a091bb2add012e2eb8643535a251 437 PIRSF PIRSF033271 30 433 5.3E-149 T 28-03-2018 IPR008322 Uncharacterised protein family UPF0261 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Gene3D G3DSA:2.160.10.10 88 239 6.5E-45 T 28-03-2018 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 236 44.486 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 119 4.7E-5 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 157 8.8E-10 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS18725 792fc8814831b97943199605fcf718d6 239 SUPERFAMILY SSF51161 44 226 3.05E-52 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS18725 792fc8814831b97943199605fcf718d6 239 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 7 237 2.0E-113 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 166 201 1.4E-9 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 88 3.1E-34 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 Gene3D G3DSA:3.30.70.250 3 87 3.2E-35 T 28-03-2018 A21D_RS18725 792fc8814831b97943199605fcf718d6 239 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A21D_RS09530 d6d27b69ce31c88e158f9e2a6b53b57d 409 Pfam PF01609 Transposase DDE domain 126 329 3.8E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A21D_RS09530 d6d27b69ce31c88e158f9e2a6b53b57d 409 SUPERFAMILY SSF53098 63 342 3.79E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS09530 d6d27b69ce31c88e158f9e2a6b53b57d 409 Gene3D G3DSA:3.90.350.10 123 310 6.5E-19 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS09530 d6d27b69ce31c88e158f9e2a6b53b57d 409 Pfam PF14294 Domain of unknown function (DUF4372) 7 69 9.7E-7 T 28-03-2018 IPR025399 Domain of unknown function DUF4372 A21D_RS03940 5e5adb4ce8ffee4e5aaf5357c6ea1c77 107 Gene3D G3DSA:1.10.10.10 1 94 8.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03940 5e5adb4ce8ffee4e5aaf5357c6ea1c77 107 SUPERFAMILY SSF46785 10 100 1.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03940 5e5adb4ce8ffee4e5aaf5357c6ea1c77 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 2.5E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal A21D_RS12405 b4e37a539dcf91eb4c19c79e3b066dba 104 Gene3D G3DSA:3.40.50.2300 2 104 6.3E-37 T 28-03-2018 A21D_RS12405 b4e37a539dcf91eb4c19c79e3b066dba 104 SUPERFAMILY SSF52794 1 102 1.65E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12405 b4e37a539dcf91eb4c19c79e3b066dba 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 94 7.4E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS00575 5cd959ad8a3ea365b7797d0a5b0edcf7 82 Pfam PF11458 Membrane-integrating protein Mistic 11 69 8.0E-14 T 28-03-2018 IPR021078 Membrane-integrating protein Mistic A21D_RS00575 5cd959ad8a3ea365b7797d0a5b0edcf7 82 Gene3D G3DSA:1.10.220.90 1 67 9.7E-24 T 28-03-2018 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 SUPERFAMILY SSF52540 194 361 9.34E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Pfam PF13167 GTP-binding GTPase N-terminal 21 109 6.5E-31 T 28-03-2018 IPR025121 GTPase HflX, N-terminal A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Gene3D G3DSA:3.40.50.300 179 356 2.0E-25 T 28-03-2018 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Pfam PF16360 GTP-binding GTPase Middle Region 111 189 1.8E-31 T 28-03-2018 IPR032305 GTP-binding protein, middle domain A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Gene3D G3DSA:1.10.287.510 21 178 0.0041 T 28-03-2018 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Pfam PF01926 50S ribosome-binding GTPase 196 315 1.4E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 4 350 1.6E-138 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 264 282 5.5E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 197 217 5.5E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 PIRSF PIRSF006809 1 409 2.8E-145 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A21D_RS17510 d3d38b88f7c9609388639041a78dc3f0 410 Hamap MF_00900 GTPase HflX [hflX]. 24 381 43.704 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 SUPERFAMILY SSF55486 8 492 1.1E-108 T 28-03-2018 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PIRSF PIRSF006615 2 498 9.1E-191 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 400 421 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 377 394 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 226 242 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 263 282 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 331 350 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 243 262 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 146 166 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 290 306 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 444 462 3.7E-77 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 5 492 6.2E-176 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A21D_RS16810 f649de7aa38716e4b023268fe26078ee 498 Gene3D G3DSA:1.10.1370.10 3 497 5.2E-43 T 28-03-2018 A21D_RS00665 a6f89c0d8350e8a3064f30a116392dac 156 SUPERFAMILY SSF55811 4 128 5.82E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS00665 a6f89c0d8350e8a3064f30a116392dac 156 PRINTS PR00502 NUDIX hydrolase family signature 40 55 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS00665 a6f89c0d8350e8a3064f30a116392dac 156 PRINTS PR00502 NUDIX hydrolase family signature 26 40 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A21D_RS00665 a6f89c0d8350e8a3064f30a116392dac 156 Pfam PF00293 NUDIX domain 5 124 5.4E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS00665 a6f89c0d8350e8a3064f30a116392dac 156 Gene3D G3DSA:3.90.79.10 1 153 2.5E-29 T 28-03-2018 A21D_RS05250 0ccdd49bd607e713df2254280b5776ab 100 SUPERFAMILY SSF52794 1 97 1.33E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS05250 0ccdd49bd607e713df2254280b5776ab 100 Gene3D G3DSA:3.40.50.2300 1 99 3.3E-17 T 28-03-2018 A21D_RS05250 0ccdd49bd607e713df2254280b5776ab 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 62 3.7E-11 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS12650 278ac662ca99b09dcdc474db967b99d8 68 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 7 67 1.6E-18 T 28-03-2018 IPR018690 Protein of unknown function DUF2187 A21D_RS03470 ccb196e54550022213650ef40fd25708 86 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 13 86 2.3E-17 T 28-03-2018 IPR013432 Putative addiction module antidote A21D_RS03470 ccb196e54550022213650ef40fd25708 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 17 59 3.6E-11 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS03470 ccb196e54550022213650ef40fd25708 86 SMART SM00966 16 61 2.3E-9 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A21D_RS03470 ccb196e54550022213650ef40fd25708 86 Gene3D G3DSA:2.10.260.10 7 85 5.3E-15 T 28-03-2018 A21D_RS03470 ccb196e54550022213650ef40fd25708 86 SUPERFAMILY SSF89447 13 67 1.45E-12 T 28-03-2018 A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 TIGRFAM TIGR03811 tyr_de_CO2_Ent: tyrosine decarboxylase 7 616 0.0 T 28-03-2018 IPR022397 Tyrosine decarboxylase, bacteria A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 SUPERFAMILY SSF53383 21 172 1.96E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 SUPERFAMILY SSF53383 217 335 1.96E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 SUPERFAMILY SSF53383 368 531 1.96E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 SUPERFAMILY SSF53383 577 610 1.96E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 Gene3D G3DSA:3.40.640.10 98 466 2.7E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS11120 c13d2f30091add9412ddea62286fe21c 620 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 213 333 7.2E-14 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A21D_RS12655 018f16ed48635fc4f71cae6fbfd48162 163 SUPERFAMILY SSF46955 27 139 4.3E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS12655 018f16ed48635fc4f71cae6fbfd48162 163 Pfam PF13411 MerR HTH family regulatory protein 25 89 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS12655 018f16ed48635fc4f71cae6fbfd48162 163 Gene3D G3DSA:1.10.1660.10 9 162 1.1E-11 T 28-03-2018 A21D_RS07395 654f38fffa0e0ba9a82c815dd283dec7 314 Pfam PF09648 YycH protein 38 255 6.5E-37 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Pfam PF01706 FliG C-terminal domain 220 326 7.0E-42 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 SUPERFAMILY SSF48029 8 101 6.8E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 197 222 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 228 248 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 116 139 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 250 270 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 274 300 2.3E-78 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 PIRSF PIRSF003161 2 336 4.4E-126 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Pfam PF14841 FliG middle domain 117 190 1.4E-31 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 SUPERFAMILY SSF48029 116 327 1.29E-70 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Pfam PF14842 FliG N-terminal domain 7 109 3.4E-36 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Gene3D G3DSA:1.10.220.30 8 84 5.4E-14 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Gene3D G3DSA:1.10.220.30 85 192 3.1E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 Gene3D G3DSA:1.10.220.30 197 336 2.6E-37 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A21D_RS17940 d11a0e6cdd7295b4c37e204e5b608ffd 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 336 8.0E-150 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A21D_RS07560 acd0e62b50dc9708740aab9b8dcb9b0c 194 Pfam PF09335 SNARE associated Golgi protein 29 155 1.8E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein A21D_RS02350 24302db1a1ad69d39eddd3c5c07802f4 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 7 117 7.0E-26 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS02350 24302db1a1ad69d39eddd3c5c07802f4 121 SUPERFAMILY SSF141530 4 119 3.01E-35 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS02350 24302db1a1ad69d39eddd3c5c07802f4 121 Gene3D G3DSA:2.40.33.40 3 118 1.3E-38 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS02350 24302db1a1ad69d39eddd3c5c07802f4 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 116 7.0E-38 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS03515 739173351a874abd1651811b754918ae 141 Gene3D G3DSA:3.30.428.10 1 139 5.5E-27 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A21D_RS03515 739173351a874abd1651811b754918ae 141 Pfam PF01230 HIT domain 13 108 6.7E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS03515 739173351a874abd1651811b754918ae 141 SUPERFAMILY SSF54197 2 113 1.18E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A21D_RS03515 739173351a874abd1651811b754918ae 141 PRINTS PR00332 Histidine triad family signature 5 21 4.0E-8 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS03515 739173351a874abd1651811b754918ae 141 PRINTS PR00332 Histidine triad family signature 94 104 4.0E-8 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS03515 739173351a874abd1651811b754918ae 141 PRINTS PR00332 Histidine triad family signature 26 44 4.0E-8 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A21D_RS14095 c280c10a59e11ced3af4fa3ef29233c3 146 SUPERFAMILY SSF82784 1 140 2.49E-42 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS14095 c280c10a59e11ced3af4fa3ef29233c3 146 Pfam PF02566 OsmC-like protein 37 140 3.0E-24 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS14095 c280c10a59e11ced3af4fa3ef29233c3 146 Gene3D G3DSA:3.30.300.20 1 143 5.6E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS07155 aaddbeec8ac294c738895139b1a9c1e1 216 SUPERFAMILY SSF161098 6 200 2.75E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07155 aaddbeec8ac294c738895139b1a9c1e1 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 214 1.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07155 aaddbeec8ac294c738895139b1a9c1e1 216 Gene3D G3DSA:1.10.3720.10 5 216 5.4E-38 T 28-03-2018 A21D_RS18680 717b673584eb6f4c8a28b3eddcd1547c 257 Gene3D G3DSA:3.40.50.1000 1 256 3.0E-40 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18680 717b673584eb6f4c8a28b3eddcd1547c 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 2.5E-59 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18680 717b673584eb6f4c8a28b3eddcd1547c 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 1.3E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS18680 717b673584eb6f4c8a28b3eddcd1547c 257 SUPERFAMILY SSF56784 1 255 1.15E-65 T 28-03-2018 IPR023214 HAD-like domain A21D_RS18680 717b673584eb6f4c8a28b3eddcd1547c 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 2.5E-64 T 28-03-2018 IPR000150 Cof family GO:0016787 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 Gene3D G3DSA:3.30.450.40 240 442 3.5E-5 T 28-03-2018 IPR029016 GAF domain-like A21D_RS00895 303834303e59323d61f5ba84107f342d 497 SMART SM00421 434 491 7.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 Pfam PF00196 Bacterial regulatory proteins, luxR family 437 491 8.7E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 467 479 7.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 451 467 7.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 437 451 7.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 Gene3D G3DSA:1.10.10.10 443 497 4.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00895 303834303e59323d61f5ba84107f342d 497 SUPERFAMILY SSF46894 428 497 3.74E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A21D_RS00895 303834303e59323d61f5ba84107f342d 497 SUPERFAMILY SSF55781 255 394 7.11E-6 T 28-03-2018 IPR029016 GAF domain-like A21D_RS09490 e6fb576ee58f81949f19e4afc011517a 146 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 145 2.5E-30 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS09490 e6fb576ee58f81949f19e4afc011517a 146 SUPERFAMILY SSF55804 7 145 3.14E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS09490 e6fb576ee58f81949f19e4afc011517a 146 Gene3D G3DSA:3.40.930.10 4 146 8.6E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS09490 e6fb576ee58f81949f19e4afc011517a 146 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS01410 0d6824aafb4907c5e4c1bea8b7f7fcd2 283 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 9.0E-13 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS01410 0d6824aafb4907c5e4c1bea8b7f7fcd2 283 PIRSF PIRSF006483 1 278 2.3E-77 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS01410 0d6824aafb4907c5e4c1bea8b7f7fcd2 283 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 8.0E-57 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.9E-92 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 34.666 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 SUPERFAMILY SSF53335 82 311 4.48E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 1.1E-101 T 28-03-2018 A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 PIRSF PIRSF000401 1 313 1.9E-103 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A21D_RS15650 b31ecfabcd50c8fed630cd1cd435fd51 315 Gene3D G3DSA:3.40.50.150 116 315 1.3E-41 T 28-03-2018 A21D_RS10835 b0b3f037d839a3fa9071a355e8b0f05c 376 Pfam PF03845 Spore germination protein 10 329 1.0E-62 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A21D_RS10835 b0b3f037d839a3fa9071a355e8b0f05c 376 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 364 2.7E-71 T 28-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A21D_RS15445 0a8ca93312a05d3541f37923709aa687 215 Gene3D G3DSA:3.40.50.150 3 213 2.6E-36 T 28-03-2018 A21D_RS15445 0a8ca93312a05d3541f37923709aa687 215 SUPERFAMILY SSF53335 30 212 8.83E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS15445 0a8ca93312a05d3541f37923709aa687 215 Pfam PF01596 O-methyltransferase 17 211 2.9E-34 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A21D_RS08065 21819e5ec47a523f074b185eed2622db 442 Pfam PF03222 Tryptophan/tyrosine permease family 38 378 1.2E-8 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 89 5.4E-33 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 7 97 9.7E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 Gene3D G3DSA:3.40.50.2300 4 100 1.0E-40 T 28-03-2018 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 SUPERFAMILY SSF52794 4 105 9.77E-39 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 125 460 3.6E-111 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A21D_RS08555 58a3e42de8d38e555f6ef6505d2144b6 467 Pfam PF02378 Phosphotransferase system, EIIC 141 406 1.8E-15 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS07195 7f5bfa93579c29cf85f179c4560d5663 389 SMART SM00471 169 305 1.3E-4 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS07195 7f5bfa93579c29cf85f179c4560d5663 389 Pfam PF13487 HD domain 226 287 3.0E-18 T 28-03-2018 A21D_RS07195 7f5bfa93579c29cf85f179c4560d5663 389 SUPERFAMILY SSF109604 163 335 3.14E-25 T 28-03-2018 A21D_RS07195 7f5bfa93579c29cf85f179c4560d5663 389 Gene3D G3DSA:1.10.3210.10 85 345 6.3E-35 T 28-03-2018 A21D_RS15485 c7081e4ce0b6ed0480adbd03922af5e7 97 SUPERFAMILY SSF53697 15 96 1.82E-10 T 28-03-2018 A21D_RS15485 c7081e4ce0b6ed0480adbd03922af5e7 97 Gene3D G3DSA:3.40.50.10490 45 97 4.7E-6 T 28-03-2018 A21D_RS15810 c663b2b9244309bb08fe1671e95ef038 209 Pfam PF01957 NfeD-like C-terminal, partner-binding 62 208 3.4E-9 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain A21D_RS15810 c663b2b9244309bb08fe1671e95ef038 209 Gene3D G3DSA:2.40.50.140 143 209 9.1E-12 T 28-03-2018 A21D_RS15810 c663b2b9244309bb08fe1671e95ef038 209 SUPERFAMILY SSF141322 148 208 3.14E-5 T 28-03-2018 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 SUPERFAMILY SSF90123 5 317 2.75E-83 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 SUPERFAMILY SSF52540 324 571 2.83E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 Gene3D G3DSA:3.40.50.300 322 576 5.5E-77 T 28-03-2018 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 SMART SM00382 360 546 3.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 Pfam PF00664 ABC transporter transmembrane region 19 289 4.2E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 Pfam PF00005 ABC transporter 351 500 1.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 Gene3D G3DSA:1.20.1560.10 1 321 1.4E-74 T 28-03-2018 A21D_RS18705 e7f7f956af476b8585b364c689f9ce5a 583 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Gene3D G3DSA:1.20.58.220 332 447 2.1E-19 T 28-03-2018 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 9 315 9.6E-72 T 28-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Pfam PF01895 PhoU domain 453 537 3.2E-19 T 28-03-2018 IPR026022 PhoU domain A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Pfam PF01895 PhoU domain 348 434 1.6E-10 T 28-03-2018 IPR026022 PhoU domain A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Gene3D G3DSA:1.20.58.220 448 540 1.8E-24 T 28-03-2018 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 SUPERFAMILY SSF109755 338 539 1.67E-49 T 28-03-2018 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Pfam PF02690 Na+/Pi-cotransporter 148 258 1.3E-17 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A21D_RS15815 d9419c94719291e16d853a7c902aa8b8 541 Pfam PF02690 Na+/Pi-cotransporter 18 153 1.7E-51 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A21D_RS18715 9d0208c599d215cde9753219cd265942 80 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 2.2E-23 T 28-03-2018 IPR005370 Uncharacterised protein family UPF0180 A21D_RS18715 9d0208c599d215cde9753219cd265942 80 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 3.0E-10 T 28-03-2018 IPR005370 Uncharacterised protein family UPF0180 A21D_RS13265 707bbd61f7827ff17ae635658fb9b415 176 PIRSF PIRSF011560 3 175 3.9E-52 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 A21D_RS13265 707bbd61f7827ff17ae635658fb9b415 176 Pfam PF06338 ComK protein 10 156 3.7E-49 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 A21D_RS11730 0ee80bfe67aa96a77199bb999ff81a04 640 Pfam PF02687 FtsX-like permease family 84 166 2.6E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS11730 0ee80bfe67aa96a77199bb999ff81a04 640 PIRSF PIRSF018968 1 635 1.6E-129 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A21D_RS09175 2fd76cf5fc2724aca34dc7eb9324ea56 392 Pfam PF02417 Chromate transporter 223 384 1.0E-38 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A21D_RS09175 2fd76cf5fc2724aca34dc7eb9324ea56 392 Pfam PF02417 Chromate transporter 9 172 1.3E-32 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A21D_RS09175 2fd76cf5fc2724aca34dc7eb9324ea56 392 PIRSF PIRSF004810 1 392 8.4E-123 T 28-03-2018 IPR014047 Chromate transporter, long chain A21D_RS09175 2fd76cf5fc2724aca34dc7eb9324ea56 392 TIGRFAM TIGR00937 2A51: chromate efflux transporter 15 385 5.0E-110 T 28-03-2018 IPR014047 Chromate transporter, long chain A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Pfam PF00041 Fibronectin type III domain 688 761 1.6E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Gene3D G3DSA:2.60.40.10 684 782 4.7E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Pfam PF00912 Transglycosylase 74 248 6.8E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SUPERFAMILY SSF53955 63 269 1.72E-67 T 28-03-2018 IPR023346 Lysozyme-like domain A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Gene3D G3DSA:3.40.710.10 270 683 8.6E-102 T 28-03-2018 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Gene3D G3DSA:1.10.3810.10 65 265 4.0E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 83 629 1.5E-169 T 28-03-2018 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SUPERFAMILY SSF56601 282 685 2.72E-105 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SUPERFAMILY SSF56601 230 252 2.72E-105 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Gene3D G3DSA:2.60.40.10 783 867 0.004 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 Pfam PF00905 Penicillin binding protein transpeptidase domain 342 587 5.1E-43 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SMART SM00060 687 766 2.1 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SMART SM00060 783 853 14.0 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A21D_RS16765 e9954e70fb84a73e4b086b00468b3e6e 929 SUPERFAMILY SSF49265 688 765 1.06E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A21D_RS17735 b1c70daac684d7b318ee155c4a57d119 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 93 9.0E-17 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A21D_RS17735 b1c70daac684d7b318ee155c4a57d119 100 Gene3D G3DSA:3.30.1330.30 1 99 1.8E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS17735 b1c70daac684d7b318ee155c4a57d119 100 SUPERFAMILY SSF55315 3 97 2.36E-25 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A21D_RS14445 1c83c40130befaeed4761be7513d9c1b 166 Pfam PF00578 AhpC/TSA family 20 142 2.0E-23 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS14445 1c83c40130befaeed4761be7513d9c1b 166 Gene3D G3DSA:3.40.30.10 5 164 8.3E-28 T 28-03-2018 A21D_RS14445 1c83c40130befaeed4761be7513d9c1b 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 163 35.059 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 A21D_RS14445 1c83c40130befaeed4761be7513d9c1b 166 SUPERFAMILY SSF52833 1 160 2.9E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS02335 197ffdb8178b39cb4a0700c57a039618 163 SUPERFAMILY SSF55804 11 154 6.41E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS02335 197ffdb8178b39cb4a0700c57a039618 163 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 15 158 1.9E-37 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS02335 197ffdb8178b39cb4a0700c57a039618 163 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 16 144 1.9E-37 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A21D_RS02335 197ffdb8178b39cb4a0700c57a039618 163 Gene3D G3DSA:3.40.930.10 11 160 7.7E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS03370 088ff3fb8731da053dfb383979ebe1d1 87 Pfam PF06196 Protein of unknown function (DUF997) 8 83 3.1E-28 T 28-03-2018 IPR010398 Protein of unknown function DUF997 A21D_RS03370 088ff3fb8731da053dfb383979ebe1d1 87 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 7 82 1.0E-26 T 28-03-2018 IPR010398 Protein of unknown function DUF997 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 Pfam PF02527 rRNA small subunit methyltransferase G 21 204 3.2E-55 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 27.426 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 PIRSF PIRSF003078 2 220 1.1E-55 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 213 4.3E-50 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 Gene3D G3DSA:3.40.50.150 1 238 2.9E-35 T 28-03-2018 A21D_RS07265 3330e19fc77f0755b609f59c739e3849 238 SUPERFAMILY SSF53335 3 237 7.54E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 Gene3D G3DSA:3.40.50.300 11 335 1.4E-73 T 28-03-2018 A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 SUPERFAMILY SSF52540 15 264 3.22E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 Pfam PF00005 ABC transporter 34 192 4.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 SMART SM00382 43 242 5.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 327 3.4E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS12335 e15017e6cbdc5cf539807da78a2db5b7 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 308 2.2E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A21D_RS07050 ff85e0ecf89ee8cdebc99ad69a33742e 231 Gene3D G3DSA:1.20.910.10 2 226 6.7E-57 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A21D_RS07050 ff85e0ecf89ee8cdebc99ad69a33742e 231 Pfam PF03070 TENA/THI-4/PQQC family 10 217 2.2E-53 T 28-03-2018 IPR004305 Thiaminase-2/PQQC A21D_RS07050 ff85e0ecf89ee8cdebc99ad69a33742e 231 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 216 1.1E-60 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A21D_RS07050 ff85e0ecf89ee8cdebc99ad69a33742e 231 SUPERFAMILY SSF48613 4 216 2.82E-65 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 Gene3D G3DSA:1.10.3720.10 25 295 4.2E-48 T 28-03-2018 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 Gene3D G3DSA:1.10.3720.10 311 576 1.4E-30 T 28-03-2018 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 381 560 3.1E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 284 3.0E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 SUPERFAMILY SSF161098 27 289 5.89E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05340 a56d67d82601d36e6a3efceb7af0d0f2 576 SUPERFAMILY SSF161098 309 566 3.66E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02915 0453ce7405aae92b8ed5a2c2a79a6b85 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.3E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A21D_RS02915 0453ce7405aae92b8ed5a2c2a79a6b85 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 6.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02915 0453ce7405aae92b8ed5a2c2a79a6b85 219 Gene3D G3DSA:1.10.3720.10 2 219 1.4E-44 T 28-03-2018 A21D_RS02915 0453ce7405aae92b8ed5a2c2a79a6b85 219 SUPERFAMILY SSF161098 13 216 7.06E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12005 9cd8e94aa1159b0992ffbebf8cd5605a 422 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 387 3.7E-53 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 195 237 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 Gene3D G3DSA:1.10.10.60 138 190 3.3E-14 T 28-03-2018 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 SUPERFAMILY SSF46689 145 192 7.79E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 Pfam PF00072 Response regulator receiver domain 7 116 1.8E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 Gene3D G3DSA:3.40.50.2300 1 125 1.4E-15 T 28-03-2018 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 SUPERFAMILY SSF52172 1 142 2.28E-19 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 SMART SM00342 158 241 3.5E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 Gene3D G3DSA:1.10.10.60 191 249 9.8E-17 T 28-03-2018 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 241 6.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 210 225 6.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 Pfam PF12833 Helix-turn-helix domain 164 242 7.0E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS01790 7745b0ad9b91f78c1fc5db2813ac922d 260 SUPERFAMILY SSF46689 194 242 5.38E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS10425 cc9dc0dec4c2fb455627d5f3a70347cd 146 ProDom PD033466 XKDJ PHAGE PHAGE-LIKE PBSX RELATED LIN1276 ELEMENT YQBJ 1 146 2.0E-41 T 28-03-2018 A21D_RS15510 366318d14e80e8fe9cc7978b1f9c44a9 158 Pfam PF01899 Na+/H+ ion antiporter subunit 9 156 1.5E-41 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A21D_RS15510 366318d14e80e8fe9cc7978b1f9c44a9 158 PIRSF PIRSF019239 1 158 3.5E-45 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A21D_RS11620 8aef968bd0f8e8dcb265bf74c34de5ef 281 Pfam PF01145 SPFH domain / Band 7 family 54 227 6.6E-23 T 28-03-2018 IPR001107 Band 7 domain A21D_RS11620 8aef968bd0f8e8dcb265bf74c34de5ef 281 SUPERFAMILY SSF117892 87 215 1.83E-12 T 28-03-2018 IPR001107 Band 7 domain A21D_RS11620 8aef968bd0f8e8dcb265bf74c34de5ef 281 SMART SM00244 49 213 6.5E-10 T 28-03-2018 IPR001107 Band 7 domain A21D_RS17915 a931a213f9a62dc751dee1a4c32a710e 455 Pfam PF02120 Flagellar hook-length control protein FliK 331 397 2.8E-15 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 Gene3D G3DSA:3.40.50.300 98 260 3.0E-26 T 28-03-2018 A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 SUPERFAMILY SSF52540 102 325 7.53E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 64 317 2.9E-56 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 Gene3D G3DSA:1.10.40.50 263 329 1.9E-19 T 28-03-2018 A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 Pfam PF03193 RsgA GTPase 84 261 4.0E-50 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 22 324 31.513 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A21D_RS03110 b7e45a809138afd895631c427b50bfaf 356 Gene3D G3DSA:2.40.50.140 16 85 5.2E-10 T 28-03-2018 A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 SUPERFAMILY SSF88697 6 71 1.14E-16 T 28-03-2018 IPR015947 PUA-like domain A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 Gene3D G3DSA:3.30.750.80 76 179 2.4E-23 T 28-03-2018 A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 Gene3D G3DSA:2.30.130.10 6 68 5.1E-14 T 28-03-2018 IPR002478 PUA domain GO:0003723 A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 104 349 6.3E-33 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 Gene3D G3DSA:3.40.50.150 181 398 5.6E-27 T 28-03-2018 A21D_RS03670 846a91508507d65f0288cb88ea9380b6 398 SUPERFAMILY SSF53335 81 392 1.37E-63 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 Gene3D G3DSA:1.10.260.40 4 60 3.4E-21 T 28-03-2018 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 Gene3D G3DSA:3.40.50.2300 170 335 1.6E-47 T 28-03-2018 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 SUPERFAMILY SSF47413 2 62 6.28E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 63 328 9.3E-36 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 3.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 3.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 Gene3D G3DSA:3.40.50.2300 61 169 2.8E-21 T 28-03-2018 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 SMART SM00354 3 74 2.0E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 SUPERFAMILY SSF53822 64 334 1.49E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS09620 10fcd2bb9884878e25e862ddb75a16ac 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 1.0E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A21D_RS10475 77b77ac3e5879585e6fae0915d33e469 362 Pfam PF04865 Baseplate J-like protein 61 317 6.0E-52 T 28-03-2018 IPR006949 Baseplate protein J-like A21D_RS02590 862b0f14d7524e73cc0e0bed303d30c0 482 PIRSF PIRSF006060 1 482 4.0E-75 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS02590 862b0f14d7524e73cc0e0bed303d30c0 482 Pfam PF13520 Amino acid permease 16 438 2.7E-38 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS06725 240605c05f26bbc2bfe724b099a1d153 528 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 357 503 9.3E-21 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A21D_RS06725 240605c05f26bbc2bfe724b099a1d153 528 Pfam PF01943 Polysaccharide biosynthesis protein 9 304 1.0E-27 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 SUPERFAMILY SSF56053 83 176 1.58E-34 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 Gene3D G3DSA:3.90.930.12 2 82 2.0E-32 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 SUPERFAMILY SSF56053 1 82 2.4E-29 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 39.014 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 Pfam PF00347 Ribosomal protein L6 11 82 1.9E-23 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 Pfam PF00347 Ribosomal protein L6 90 164 4.4E-18 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.6E-77 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 6.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 6.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 6.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 Gene3D G3DSA:3.90.930.12 83 178 2.5E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06300 226c690921ac3b4a126341aef19e351f 178 PIRSF PIRSF002162 1 177 3.5E-52 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS08150 6b9a0347296f9fa72eb3245a96d8a802 340 Pfam PF03601 Conserved hypothetical protein 698 18 318 3.3E-86 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 193 424 1.0E-76 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 Gene3D G3DSA:3.40.50.720 193 426 2.8E-75 T 28-03-2018 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 SMART SM00839 195 424 3.0E-93 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 Gene3D G3DSA:3.40.50.10860 45 179 1.1E-48 T 28-03-2018 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 SUPERFAMILY SSF53223 17 195 1.15E-63 T 28-03-2018 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 SUPERFAMILY SSF51735 193 425 5.99E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 PIRSF PIRSF000185 7 426 4.2E-169 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 104 118 2.0E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 226 246 2.0E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 184 206 2.0E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 352 363 2.0E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 175 1.7E-52 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS16490 c277b7e6260281b66effdf3ab6791a55 426 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 112 125 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A21D_RS05710 bb1b3947fc494519b4b4708b6cd83882 96 Pfam PF06713 Bacterial PH domain 21 81 4.2E-11 T 28-03-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 A21D_RS01775 82d1da42efbf421b3432b3c01388ce2f 362 Pfam PF00899 ThiF family 121 347 1.0E-25 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS01775 82d1da42efbf421b3432b3c01388ce2f 362 Gene3D G3DSA:3.40.50.720 114 353 4.6E-35 T 28-03-2018 A21D_RS01775 82d1da42efbf421b3432b3c01388ce2f 362 SUPERFAMILY SSF69572 121 353 1.96E-33 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 Pfam PF00436 Single-strand binding protein family 2 103 1.9E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 Gene3D G3DSA:2.40.50.140 1 122 4.2E-41 T 28-03-2018 A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 168 1.6E-50 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 SUPERFAMILY SSF50249 1 168 2.95E-57 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.607 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A21D_RS07330 ec9c2453909066f1a1fb5896a9edd3b9 168 PIRSF PIRSF002070 1 158 9.4E-40 T 28-03-2018 A21D_RS06710 07747a7928a7dba1f655a179d0f309d9 99 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 17 99 5.7E-36 T 28-03-2018 IPR012504 Sporulation protein YabP A21D_RS06710 07747a7928a7dba1f655a179d0f309d9 99 Pfam PF07873 YabP family 17 82 4.5E-22 T 28-03-2018 IPR022476 Sporulation protein YabP/YqfC A21D_RS06710 07747a7928a7dba1f655a179d0f309d9 99 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 16 99 2.0E-35 T 28-03-2018 IPR012504 Sporulation protein YabP A21D_RS06710 07747a7928a7dba1f655a179d0f309d9 99 PIRSF PIRSF011576 1 99 7.2E-42 T 28-03-2018 IPR012504 Sporulation protein YabP A21D_RS04090 3df7aaa9e567a6b6d90232ff6c638be1 138 SUPERFAMILY SSF53062 1 126 1.96E-30 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS04090 3df7aaa9e567a6b6d90232ff6c638be1 138 Pfam PF03610 PTS system fructose IIA component 3 110 2.0E-18 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS04090 3df7aaa9e567a6b6d90232ff6c638be1 138 Gene3D G3DSA:3.40.50.510 1 138 1.2E-28 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS14685 3e7d96600fe4f69abaf813814a96e475 93 Pfam PF06961 Protein of unknown function (DUF1294) 15 69 4.6E-25 T 28-03-2018 IPR010718 Protein of unknown function DUF1294 A21D_RS01550 53bc25537a8a724dd1d11bf87c24c0e7 121 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 14 71 2.0E-15 T 28-03-2018 IPR020108 Spore coat protein CotD A21D_RS01550 53bc25537a8a724dd1d11bf87c24c0e7 121 Gene3D G3DSA:2.170.180.11 6 72 0.0011 T 28-03-2018 IPR023311 Methuselah ectodomain, domain 2 A21D_RS01550 53bc25537a8a724dd1d11bf87c24c0e7 121 Pfam PF11122 Inner spore coat protein D 13 100 5.4E-23 T 28-03-2018 IPR020108 Spore coat protein CotD A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 Gene3D G3DSA:3.40.50.2300 3 151 1.4E-31 T 28-03-2018 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 SMART SM00448 4 118 2.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 SUPERFAMILY SSF52738 161 347 1.96E-59 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 Pfam PF00072 Response regulator receiver domain 6 110 1.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 Gene3D G3DSA:3.40.50.180 153 348 1.8E-69 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 PIRSF PIRSF000876 1 348 1.2E-128 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 Pfam PF01339 CheB methylesterase 163 342 4.1E-57 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 SUPERFAMILY SSF52172 4 114 5.98E-29 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS17835 ec23d6fe01580427b91a0c506529e373 348 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 348 37.592 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A21D_RS19565 ff33e23e69d1da48011cb4e9ec6f0c11 133 SUPERFAMILY SSF140931 4 118 3.27E-23 T 28-03-2018 IPR003812 Fido domain A21D_RS19565 ff33e23e69d1da48011cb4e9ec6f0c11 133 Gene3D G3DSA:1.10.3290.10 1 131 8.9E-17 T 28-03-2018 IPR003812 Fido domain A21D_RS19565 ff33e23e69d1da48011cb4e9ec6f0c11 133 Pfam PF02661 Fic/DOC family 4 87 2.0E-12 T 28-03-2018 IPR003812 Fido domain A21D_RS06665 388bc91d8a3b1886afa8dd0330016cf4 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 7.0E-66 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A21D_RS06665 388bc91d8a3b1886afa8dd0330016cf4 180 SUPERFAMILY SSF53271 1 177 4.85E-58 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS06665 388bc91d8a3b1886afa8dd0330016cf4 180 Gene3D G3DSA:3.40.50.2020 1 178 1.4E-45 T 28-03-2018 A21D_RS06665 388bc91d8a3b1886afa8dd0330016cf4 180 Pfam PF00156 Phosphoribosyl transferase domain 12 159 2.5E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS15695 dc4b4a86e6206520e8a274a25adfed73 103 Pfam PF07873 YabP family 28 91 8.2E-16 T 28-03-2018 IPR022476 Sporulation protein YabP/YqfC A21D_RS15695 dc4b4a86e6206520e8a274a25adfed73 103 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 10 92 4.0E-31 T 28-03-2018 IPR022477 Sporulation protein YqfC A21D_RS13890 c408908f4607e7544d846d632a6b7f25 89 Pfam PF11256 Protein of unknown function (DUF3055) 10 86 4.9E-20 T 28-03-2018 IPR021415 Protein of unknown function DUF3055 A21D_RS18555 103bc8bb6d0a60a9513e6f765649e791 314 Pfam PF01040 UbiA prenyltransferase family 43 292 6.9E-51 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A21D_RS18555 103bc8bb6d0a60a9513e6f765649e791 314 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 32 307 3.3E-87 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A21D_RS18555 103bc8bb6d0a60a9513e6f765649e791 314 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 309 17.172 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A21D_RS18555 103bc8bb6d0a60a9513e6f765649e791 314 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 86 108 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 SUPERFAMILY SSF89957 12 197 9.28E-54 T 28-03-2018 IPR029756 MTH1187/YkoF-like A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 Pfam PF07615 YKOF-related Family 13 92 1.3E-27 T 28-03-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 Pfam PF07615 YKOF-related Family 119 198 6.3E-27 T 28-03-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 Gene3D G3DSA:3.30.70.930 9 90 3.1E-18 T 28-03-2018 IPR029756 MTH1187/YkoF-like A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 Gene3D G3DSA:3.30.70.930 113 196 2.5E-13 T 28-03-2018 IPR029756 MTH1187/YkoF-like A21D_RS09690 7e22dcc19b44553e07315d60c3852299 205 PIRSF PIRSF021331 5 200 5.1E-78 T 28-03-2018 IPR015835 Hydroxymethyl pyrimidine (HMP)/thiamine binding protein GO:0030975 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 230 2.7E-48 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 Pfam PF00849 RNA pseudouridylate synthase 66 200 2.0E-21 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 SMART SM00363 6 63 6.9E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 Gene3D G3DSA:3.30.2350.10 65 245 4.6E-39 T 28-03-2018 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 SUPERFAMILY SSF55120 49 242 2.28E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 SUPERFAMILY SSF55174 5 71 4.32E-16 T 28-03-2018 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 Pfam PF01479 S4 domain 6 52 1.3E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS16420 140be92d41ec00047f1acb4819bfa1a1 245 Gene3D G3DSA:3.10.290.10 3 64 1.1E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS02420 77adace3dd1e20f30f01647aa54603d2 365 Pfam PF13458 Periplasmic binding protein 32 326 7.9E-13 T 28-03-2018 IPR028081 Leucine-binding protein domain A21D_RS02420 77adace3dd1e20f30f01647aa54603d2 365 Gene3D G3DSA:3.40.50.2300 27 341 4.7E-21 T 28-03-2018 A21D_RS02420 77adace3dd1e20f30f01647aa54603d2 365 SUPERFAMILY SSF53822 30 357 2.74E-32 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A21D_RS07125 3485495cc9b309939136a4633f8169e3 226 Pfam PF01712 Deoxynucleoside kinase 15 214 1.3E-66 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain A21D_RS07125 3485495cc9b309939136a4633f8169e3 226 Gene3D G3DSA:3.40.50.300 13 223 2.5E-46 T 28-03-2018 A21D_RS07125 3485495cc9b309939136a4633f8169e3 226 PIRSF PIRSF000705 2 221 8.4E-65 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A21D_RS07125 3485495cc9b309939136a4633f8169e3 226 SUPERFAMILY SSF52540 14 213 1.15E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14625 aa1924a59f3584bb6939a3d4372a0785 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 2.0E-39 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A21D_RS14625 aa1924a59f3584bb6939a3d4372a0785 123 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 4.7E-34 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A21D_RS14625 aa1924a59f3584bb6939a3d4372a0785 123 Gene3D G3DSA:3.60.90.10 1 123 5.3E-38 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A21D_RS14625 aa1924a59f3584bb6939a3d4372a0785 123 SUPERFAMILY SSF56276 4 114 3.53E-36 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A21D_RS14625 aa1924a59f3584bb6939a3d4372a0785 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 29.236 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 Pfam PF01979 Amidohydrolase family 79 364 4.6E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 SUPERFAMILY SSF51556 81 334 4.08E-7 T 28-03-2018 IPR032466 Metal-dependent hydrolase A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 Pfam PF13382 Adenine deaminase C-terminal domain 421 566 4.4E-28 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 Gene3D G3DSA:2.30.40.10 276 373 2.3E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 SUPERFAMILY SSF51338 334 370 2.23E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 SUPERFAMILY SSF51338 22 81 2.23E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS04985 b46fdd2c62d2d321c5d6b5862dd82f9c 575 Gene3D G3DSA:2.30.40.10 11 109 3.4E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A21D_RS11720 d51acd0dc4ab3e17bdd527a84c2d7d45 81 Gene3D G3DSA:2.20.28.10 1 22 0.0097 T 28-03-2018 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 SUPERFAMILY SSF90123 5 316 1.7E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 SMART SM00382 361 548 3.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 Pfam PF00005 ABC transporter 352 501 4.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 Gene3D G3DSA:1.20.1560.10 1 318 2.6E-36 T 28-03-2018 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 Gene3D G3DSA:3.40.50.300 324 575 2.8E-67 T 28-03-2018 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 Pfam PF00664 ABC transporter transmembrane region 16 279 1.2E-23 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 SUPERFAMILY SSF52540 331 572 3.66E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03870 393668219fcedfe7837f1d00f1bc1c56 578 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 15 543 1.9E-158 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A21D_RS06220 03002780f449c8555c8f7f5b370f06f3 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 35.633 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 A21D_RS06220 03002780f449c8555c8f7f5b370f06f3 265 Pfam PF02361 Cobalt transport protein 14 236 4.1E-56 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A21D_RS05180 061a57ebd0832d8bde284d9a3d398578 117 Pfam PF07252 Protein of unknown function (DUF1433) 35 89 1.2E-9 T 28-03-2018 IPR009881 Protein of unknown function DUF1433 A21D_RS05180 061a57ebd0832d8bde284d9a3d398578 117 Gene3D G3DSA:3.10.450.130 31 115 4.6E-16 T 28-03-2018 A21D_RS00390 24f45271ea015f1392ba0db50a0c64e2 202 Pfam PF09335 SNARE associated Golgi protein 30 159 1.8E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein A21D_RS10525 401c81d71c7407531ceb2fc168804ea1 388 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 140 265 4.9E-30 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A21D_RS10525 401c81d71c7407531ceb2fc168804ea1 388 SMART SM00382 136 268 2.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS10525 401c81d71c7407531ceb2fc168804ea1 388 Gene3D G3DSA:3.40.50.300 23 338 1.0E-33 T 28-03-2018 A21D_RS10525 401c81d71c7407531ceb2fc168804ea1 388 SUPERFAMILY SSF52540 100 322 8.3E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10525 401c81d71c7407531ceb2fc168804ea1 388 ProSitePatterns PS00674 AAA-protein family signature. 238 257 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A21D_RS10640 137a630e54131d7036ba87a631efa7bf 306 Gene3D G3DSA:1.10.3720.10 3 293 5.6E-49 T 28-03-2018 A21D_RS10640 137a630e54131d7036ba87a631efa7bf 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 9.3E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10640 137a630e54131d7036ba87a631efa7bf 306 SUPERFAMILY SSF161098 89 289 3.01E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02905 b3efd26aa70fdbc7b66300e33c9a4241 162 Pfam PF12688 Tetratrico peptide repeat 38 156 2.0E-12 T 28-03-2018 A21D_RS02905 b3efd26aa70fdbc7b66300e33c9a4241 162 SUPERFAMILY SSF48452 6 154 6.5E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02905 b3efd26aa70fdbc7b66300e33c9a4241 162 Gene3D G3DSA:1.25.40.10 59 154 1.1E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS02905 b3efd26aa70fdbc7b66300e33c9a4241 162 Gene3D G3DSA:1.25.40.10 3 58 5.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS12605 7ea77c423fff7942bc4a31269b145fbc 117 SUPERFAMILY SSF53187 27 116 1.01E-18 T 28-03-2018 A21D_RS12605 7ea77c423fff7942bc4a31269b145fbc 117 Gene3D G3DSA:3.40.630.10 1 117 3.3E-26 T 28-03-2018 A21D_RS12605 7ea77c423fff7942bc4a31269b145fbc 117 Pfam PF01546 Peptidase family M20/M25/M40 16 110 2.9E-10 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS06020 670cd4843f3a69dde18d93ddc4458bd9 352 Gene3D G3DSA:1.10.3470.10 28 352 2.7E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS06020 670cd4843f3a69dde18d93ddc4458bd9 352 SUPERFAMILY SSF81345 34 348 8.11E-50 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS06020 670cd4843f3a69dde18d93ddc4458bd9 352 Pfam PF01032 FecCD transport family 69 348 4.0E-39 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 Gene3D G3DSA:3.40.50.1820 395 668 4.3E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 Pfam PF00326 Prolyl oligopeptidase family 463 660 5.9E-42 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 Pfam PF07676 WD40-like Beta Propeller Repeat 62 86 3.4E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 SUPERFAMILY SSF82171 21 372 3.53E-23 T 28-03-2018 A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 SUPERFAMILY SSF53474 404 659 5.27E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 Gene3D G3DSA:2.140.10.30 15 151 2.0E-10 T 28-03-2018 A21D_RS05205 afbfb55b9c6dd79ca7f97ccd5ab9a8fb 671 Gene3D G3DSA:2.140.10.30 176 394 1.2E-7 T 28-03-2018 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 SUPERFAMILY SSF47203 257 422 8.38E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 SUPERFAMILY SSF56645 25 263 1.57E-69 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 143 1.6E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 415 1.5E-36 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Gene3D G3DSA:1.10.540.10 1 145 3.3E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 2.1E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Gene3D G3DSA:1.20.140.10 426 594 5.2E-13 T 28-03-2018 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Gene3D G3DSA:2.40.110.10 146 240 6.3E-31 T 28-03-2018 A21D_RS00280 6673c19770e62f5a791c4e875692e959 594 Gene3D G3DSA:1.20.140.10 241 425 4.8E-52 T 28-03-2018 A21D_RS03735 d9bb5c4c6c70cdd52ab5085a919e2d82 158 SUPERFAMILY SSF54637 2 151 8.73E-51 T 28-03-2018 IPR029069 HotDog domain A21D_RS03735 d9bb5c4c6c70cdd52ab5085a919e2d82 158 Pfam PF03061 Thioesterase superfamily 26 97 1.4E-19 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS03735 d9bb5c4c6c70cdd52ab5085a919e2d82 158 Gene3D G3DSA:3.10.129.10 1 154 1.0E-50 T 28-03-2018 A21D_RS10365 292771a49d194b2d33a260d9e7f4b8c3 175 Pfam PF08281 Sigma-70, region 4 103 153 8.1E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10365 292771a49d194b2d33a260d9e7f4b8c3 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 52 157 5.1E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10365 292771a49d194b2d33a260d9e7f4b8c3 175 SUPERFAMILY SSF88659 82 157 1.18E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS10365 292771a49d194b2d33a260d9e7f4b8c3 175 Gene3D G3DSA:1.10.10.10 65 160 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS00325 70c33f8eccdab7b1da067f063b5f6939 260 Gene3D G3DSA:3.30.420.60 132 259 2.9E-14 T 28-03-2018 A21D_RS10455 2681f6f832adf5070ab5f7570f1d689f 221 SUPERFAMILY SSF54106 161 221 9.55E-7 T 28-03-2018 IPR018392 LysM domain A21D_RS10455 2681f6f832adf5070ab5f7570f1d689f 221 Gene3D G3DSA:3.10.350.10 161 221 6.1E-14 T 28-03-2018 A21D_RS10455 2681f6f832adf5070ab5f7570f1d689f 221 Pfam PF01476 LysM domain 164 221 9.7E-17 T 28-03-2018 IPR018392 LysM domain A21D_RS10455 2681f6f832adf5070ab5f7570f1d689f 221 SMART SM00257 163 221 1.1E-7 T 28-03-2018 IPR018392 LysM domain A21D_RS05005 7045ca4e56fda919b80ff64f5133cf5e 210 Pfam PF01810 LysE type translocator 13 201 1.2E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A21D_RS05435 2d2a974ea51d192e2d57641d247fdde1 90 Gene3D G3DSA:1.20.58.130 6 68 0.0011 T 28-03-2018 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 Pfam PF00491 Arginase family 47 309 4.3E-51 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 SUPERFAMILY SSF52768 9 315 1.53E-69 T 28-03-2018 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 Hamap MF_00737 Formimidoylglutamase [hutG]. 5 311 36.225 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 PIRSF PIRSF036979 20 317 6.1E-31 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 310 3.5E-84 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A21D_RS12560 ca378249116eef00e141a549bc7f3ff8 320 Gene3D G3DSA:3.40.800.10 1 320 1.3E-71 T 28-03-2018 A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 Gene3D G3DSA:3.40.190.10 289 346 2.9E-6 T 28-03-2018 A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 186 485 1.6E-41 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 PIRSF PIRSF002741 100 598 7.2E-51 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 Gene3D G3DSA:3.10.105.10 357 566 5.0E-13 T 28-03-2018 A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 Pfam PF12793 Sugar transport-related sRNA regulator N-term 18 122 6.4E-21 T 28-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 SUPERFAMILY SSF53850 143 597 8.51E-73 T 28-03-2018 A21D_RS11900 40ff8245da6a504cfd0ffe329cd5b938 598 Gene3D G3DSA:3.90.76.10 153 288 1.1E-29 T 28-03-2018 A21D_RS19560 e6e94664bfb7315f652b40d6778afe36 105 Gene3D G3DSA:1.20.810.10 8 92 1.4E-4 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A21D_RS05050 f65764be8b8e130f01807f031caa6990 261 Hamap MF_00668 6-carboxyhexanoate--CoA ligase [bioW]. 6 258 48.278 T 28-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A21D_RS05050 f65764be8b8e130f01807f031caa6990 261 Pfam PF03744 6-carboxyhexanoate--CoA ligase 7 257 1.6E-79 T 28-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A21D_RS05050 f65764be8b8e130f01807f031caa6990 261 TIGRFAM TIGR01204 bioW: 6-carboxyhexanoate--CoA ligase 20 257 1.7E-85 T 28-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A21D_RS05050 f65764be8b8e130f01807f031caa6990 261 ProDom PD017229 LIGASE SYNTHASE BIOTIN MAGNESIUM PIMELOYL-COA 6-CARBOXYHEXANOATE--COA BIOSYNTHESIS 6-CARBOXYHEXANOATE-COA BIOW COA 1 231 2.0E-68 T 28-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 A21D_RS15755 10efb550f75fc1035b894b6006f1be3b 266 Gene3D G3DSA:3.40.50.300 30 266 7.1E-5 T 28-03-2018 A21D_RS15755 10efb550f75fc1035b894b6006f1be3b 266 Pfam PF03618 Kinase/pyrophosphorylase 6 260 5.9E-96 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 A21D_RS15755 10efb550f75fc1035b894b6006f1be3b 266 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 59.522 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 Pfam PF08279 HTH domain 9 39 2.0E-4 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 Hamap MF_01814 Transcription factor FapR [fapR]. 1 186 38.643 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 Gene3D G3DSA:3.10.129.10 47 186 3.0E-20 T 28-03-2018 A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 PIRSF PIRSF037733 1 189 3.1E-84 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 SUPERFAMILY SSF46785 5 53 2.22E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 SUPERFAMILY SSF54637 74 180 6.02E-24 T 28-03-2018 IPR029069 HotDog domain A21D_RS18120 1bb4457680109772ce84d617fc59ef13 190 Gene3D G3DSA:1.10.10.10 2 46 0.0014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18050 04af9fccd2db683e3bdb47f49ce3b6aa 129 Pfam PF11068 YlqD protein 1 127 1.9E-32 T 28-03-2018 IPR021297 YlqD protein A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 4.3E-29 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 SUPERFAMILY SSF55174 2 200 1.7E-69 T 28-03-2018 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Pfam PF01479 S4 domain 93 139 5.5E-22 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 3.5E-84 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Gene3D G3DSA:1.10.1050.10 1 97 8.5E-41 T 28-03-2018 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Gene3D G3DSA:3.10.290.10 98 141 4.1E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 SMART SM01390 3 91 7.8E-45 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 SMART SM00363 92 156 5.7E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 36.168 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A21D_RS14390 7052da6c64dcb03b19bc200e250af173 200 Gene3D G3DSA:1.10.1050.10 142 200 8.8E-16 T 28-03-2018 A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 152 2.2E-41 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 SUPERFAMILY SSF55486 2 155 4.39E-45 T 28-03-2018 A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 Pfam PF02130 Uncharacterized protein family UPF0054 12 151 4.8E-48 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 23.843 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A21D_RS15715 9c0f3de699fd3fe0176f1f9c653e8320 156 Gene3D G3DSA:3.40.390.30 1 156 1.4E-50 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 PRINTS PR00986 Valyl-tRNA synthetase signature 447 468 9.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 9.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 PRINTS PR00986 Valyl-tRNA synthetase signature 44 55 9.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 9.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 PRINTS PR00986 Valyl-tRNA synthetase signature 353 366 9.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Gene3D G3DSA:1.10.730.10 512 749 6.3E-83 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Gene3D G3DSA:3.40.50.620 7 231 1.5E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Gene3D G3DSA:3.90.740.10 240 447 8.5E-66 T 28-03-2018 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 SUPERFAMILY SSF52374 10 200 6.07E-144 T 28-03-2018 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 SUPERFAMILY SSF52374 348 577 6.07E-144 T 28-03-2018 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Gene3D G3DSA:1.10.287.380 809 879 5.6E-26 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 10 881 16.124 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 SUPERFAMILY SSF47323 579 831 1.46E-77 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 816 881 7.7E-25 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 12 863 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 SUPERFAMILY SSF50677 199 349 2.49E-64 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 SUPERFAMILY SSF46589 816 880 3.03E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Pfam PF08264 Anticodon-binding domain of tRNA 610 757 5.2E-45 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A21D_RS15150 83f2e441ba9a300b9290b825070c8a42 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 566 1.3E-221 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A21D_RS04155 0ebc504f805697612bb746734eba4476 156 Pfam PF03682 Uncharacterised protein family (UPF0158) 5 152 3.7E-11 T 28-03-2018 IPR005361 Uncharacterised protein family UPF0158 A21D_RS19445 82757a49b62797848f908a6471623233 179 Pfam PF03358 NADPH-dependent FMN reductase 2 141 2.7E-25 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A21D_RS19445 82757a49b62797848f908a6471623233 179 SUPERFAMILY SSF52218 2 172 4.66E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS19445 82757a49b62797848f908a6471623233 179 Gene3D G3DSA:3.40.50.360 1 179 1.1E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS17075 1b359fcad355bd8ff86d54611b1ab4c1 310 Gene3D G3DSA:3.10.270.10 39 303 2.8E-83 T 28-03-2018 A21D_RS17075 1b359fcad355bd8ff86d54611b1ab4c1 310 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 12 303 2.3E-63 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A21D_RS17075 1b359fcad355bd8ff86d54611b1ab4c1 310 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 40 305 32.463 T 28-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A21D_RS17075 1b359fcad355bd8ff86d54611b1ab4c1 310 Pfam PF02649 Type I GTP cyclohydrolase folE2 40 300 7.0E-75 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 461 9.5E-118 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 191 209 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 358 380 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 430 450 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 219 238 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 96 118 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 PRINTS PR00175 Sodium/alanine symporter signature 314 332 2.4E-40 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS09380 29113699f8d63ed55b9e8672632eba14 493 Pfam PF01235 Sodium:alanine symporter family 59 464 4.0E-110 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS07855 19035241305e2829afdcc318dd931fa5 341 Pfam PF04471 Restriction endonuclease 196 310 2.6E-20 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A21D_RS07855 19035241305e2829afdcc318dd931fa5 341 PIRSF PIRSF031853 1 337 9.9E-98 T 28-03-2018 IPR016984 Uncharacterised conserved protein UCP031853 A21D_RS07855 19035241305e2829afdcc318dd931fa5 341 Gene3D G3DSA:3.40.1350.10 187 317 5.0E-18 T 28-03-2018 A21D_RS07855 19035241305e2829afdcc318dd931fa5 341 SUPERFAMILY SSF52980 200 314 1.61E-11 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS08920 e47511f70c16937a85d882733396af2e 284 Gene3D G3DSA:3.40.50.10490 103 279 1.1E-34 T 28-03-2018 A21D_RS08920 e47511f70c16937a85d882733396af2e 284 Gene3D G3DSA:1.10.10.10 5 102 6.9E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08920 e47511f70c16937a85d882733396af2e 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 81 9.7E-27 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A21D_RS08920 e47511f70c16937a85d882733396af2e 284 SUPERFAMILY SSF46689 9 82 2.69E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS08920 e47511f70c16937a85d882733396af2e 284 Pfam PF01380 SIS domain 130 258 6.5E-16 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A21D_RS08920 e47511f70c16937a85d882733396af2e 284 SUPERFAMILY SSF53697 101 281 1.67E-40 T 28-03-2018 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 139 730 5.4E-175 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 Pfam PF02867 Ribonucleotide reductase, barrel domain 216 727 5.2E-148 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 SUPERFAMILY SSF48168 9 214 1.7E-55 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 432 443 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 550 573 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 291 310 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 484 507 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 522 544 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 PRINTS PR01183 Ribonucleotide reductase large chain signature 611 638 5.6E-38 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 600 622 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 Gene3D G3DSA:3.20.70.20 115 735 9.5E-191 T 28-03-2018 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 137 213 1.5E-18 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08810 066e9a31a22a2700539a3a8b3aee7ec4 743 SUPERFAMILY SSF51998 215 742 1.74E-170 T 28-03-2018 A21D_RS15570 13064a16628e2283fbeef1c08edae356 248 Pfam PF13649 Methyltransferase domain 38 133 2.6E-17 T 28-03-2018 A21D_RS15570 13064a16628e2283fbeef1c08edae356 248 Gene3D G3DSA:2.20.25.110 139 203 3.9E-16 T 28-03-2018 A21D_RS15570 13064a16628e2283fbeef1c08edae356 248 Gene3D G3DSA:3.40.50.150 2 137 1.5E-18 T 28-03-2018 A21D_RS15570 13064a16628e2283fbeef1c08edae356 248 SUPERFAMILY SSF53335 3 246 1.48E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 Gene3D G3DSA:3.40.605.10 22 301 2.9E-79 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 68.653 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 SUPERFAMILY SSF53720 4 511 3.27E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 Gene3D G3DSA:3.40.309.10 302 490 4.9E-63 T 28-03-2018 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 1.4E-246 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A21D_RS12695 3a246fc3165968a546b6997757e1f218 515 Pfam PF00171 Aldehyde dehydrogenase family 49 510 1.3E-151 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 SUPERFAMILY SSF51735 105 289 3.31E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 1.9E-64 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 SUPERFAMILY SSF52283 3 137 1.34E-36 T 28-03-2018 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 320 3.2E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 Gene3D G3DSA:3.40.50.720 116 288 2.3E-58 T 28-03-2018 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 Gene3D G3DSA:3.40.50.720 3 115 3.9E-33 T 28-03-2018 A21D_RS13915 413f93cfd2f1841e1a3d11170f2a46f9 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 TIGRFAM TIGR00492 alr: alanine racemase 6 370 1.7E-125 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 SUPERFAMILY SSF51419 12 235 7.63E-63 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 Gene3D G3DSA:2.40.37.10 230 373 6.4E-54 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 67 85 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 204 231 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 279 294 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 161 172 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 353 366 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 299 316 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 126 138 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 31 47 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 PRINTS PR00992 Alanine racemase signature 262 277 8.5E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 Pfam PF00842 Alanine racemase, C-terminal domain 247 370 3.6E-41 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 SUPERFAMILY SSF50621 241 371 2.02E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 SMART SM01005 246 371 2.0E-64 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 Hamap MF_01201 Alanine racemase. 5 371 34.675 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 Gene3D G3DSA:3.20.20.10 1 229 2.0E-48 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS10015 44f28bf475c92f83a58c1d42ad5910fa 373 Pfam PF01168 Alanine racemase, N-terminal domain 12 231 4.5E-66 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 Gene3D G3DSA:3.40.50.1000 62 181 2.9E-14 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 2 162 4.4E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 3 158 3.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 Gene3D G3DSA:1.10.150.240 13 61 1.7E-8 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 SUPERFAMILY SSF56784 3 182 6.01E-30 T 28-03-2018 IPR023214 HAD-like domain A21D_RS08115 44d22941ea4d6af46f8e65ecd2d9150c 187 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 162 2.3E-21 T 28-03-2018 IPR023214 HAD-like domain A21D_RS03730 9a8b9f932f446339f583cad9d96efe42 149 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 30.906 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 A21D_RS03730 9a8b9f932f446339f583cad9d96efe42 149 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 144 6.4E-41 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 A21D_RS09705 bac53ac833fedc31b22d6bda7df94476 331 Gene3D G3DSA:3.40.190.10 34 156 8.0E-19 T 28-03-2018 A21D_RS09705 bac53ac833fedc31b22d6bda7df94476 331 Gene3D G3DSA:3.40.190.10 157 330 1.1E-33 T 28-03-2018 A21D_RS09705 bac53ac833fedc31b22d6bda7df94476 331 SUPERFAMILY SSF53850 39 329 4.91E-67 T 28-03-2018 A21D_RS09705 bac53ac833fedc31b22d6bda7df94476 331 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 328 2.1E-93 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A21D_RS09705 bac53ac833fedc31b22d6bda7df94476 331 Pfam PF16868 NMT1-like family 42 328 5.7E-81 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A21D_RS09835 ed48c7d32fcb8adf0911b4d0e6bc6048 305 Gene3D G3DSA:3.40.50.300 2 260 3.7E-61 T 28-03-2018 A21D_RS09835 ed48c7d32fcb8adf0911b4d0e6bc6048 305 SMART SM00382 30 211 8.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09835 ed48c7d32fcb8adf0911b4d0e6bc6048 305 Pfam PF00005 ABC transporter 22 162 8.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09835 ed48c7d32fcb8adf0911b4d0e6bc6048 305 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS09835 ed48c7d32fcb8adf0911b4d0e6bc6048 305 SUPERFAMILY SSF52540 5 227 3.37E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS10915 2af34ec98f62e325a2326387d98a2149 204 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 114 166 3.9E-9 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS10915 2af34ec98f62e325a2326387d98a2149 204 Hamap MF_01515 UPF0316 protein . 6 174 31.391 T 28-03-2018 IPR022930 Protein of unknown function UPF0316 A21D_RS07980 ae2f8bce05f48767ee1e82fe3bada9b9 432 Pfam PF07690 Major Facilitator Superfamily 42 283 1.5E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS07980 ae2f8bce05f48767ee1e82fe3bada9b9 432 Gene3D G3DSA:1.20.1250.20 234 432 3.4E-22 T 28-03-2018 A21D_RS07980 ae2f8bce05f48767ee1e82fe3bada9b9 432 Gene3D G3DSA:1.20.1250.20 2 233 3.2E-23 T 28-03-2018 A21D_RS07980 ae2f8bce05f48767ee1e82fe3bada9b9 432 SUPERFAMILY SSF103473 18 426 1.44E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 PIRSF PIRSF037785 17 195 5.7E-73 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 Pfam PF03838 Recombination protein U 26 191 1.1E-64 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 SUPERFAMILY SSF52980 28 194 1.8E-62 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 Gene3D G3DSA:3.40.1350.10 27 193 6.9E-60 T 28-03-2018 A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 TIGRFAM TIGR00648 recU: recombination protein U 25 193 4.5E-74 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS16770 ef278a88a0e0a09070a8c41aba6f3b78 195 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 195 88.94 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 A21D_RS14715 6ace6bc507f7f76894c4626ddb50cdb0 223 SMART SM00382 26 208 2.7E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14715 6ace6bc507f7f76894c4626ddb50cdb0 223 Pfam PF00005 ABC transporter 18 157 1.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS14715 6ace6bc507f7f76894c4626ddb50cdb0 223 SUPERFAMILY SSF52540 2 205 1.36E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14715 6ace6bc507f7f76894c4626ddb50cdb0 223 Gene3D G3DSA:3.40.50.300 1 221 6.0E-57 T 28-03-2018 A21D_RS14715 6ace6bc507f7f76894c4626ddb50cdb0 223 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02365 3429ced212ebe9d7d20daa58d45bd9bd 141 Pfam PF06923 Glucitol operon activator protein (GutM) 5 109 9.3E-35 T 28-03-2018 IPR009693 Glucitol operon activator A21D_RS02365 3429ced212ebe9d7d20daa58d45bd9bd 141 PIRSF PIRSF011474 1 138 1.9E-47 T 28-03-2018 IPR009693 Glucitol operon activator A21D_RS18885 a60c8bfbddbaf56d919d6668bcd9c8a9 576 Pfam PF02554 Carbon starvation protein CstA 1 378 2.8E-127 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A21D_RS18885 a60c8bfbddbaf56d919d6668bcd9c8a9 576 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 403 524 6.3E-33 T 28-03-2018 IPR025299 CstA, C-terminal domain A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 PRINTS PR01727 Prokaryotic integration host factor signature 86 100 5.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 PRINTS PR01727 Prokaryotic integration host factor signature 52 67 5.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 PRINTS PR01727 Prokaryotic integration host factor signature 70 83 5.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 SMART SM00411 13 102 4.2E-53 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 Gene3D G3DSA:4.10.520.10 6 102 9.7E-40 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 SUPERFAMILY SSF47729 13 102 3.09E-36 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 Pfam PF00216 Bacterial DNA-binding protein 13 102 3.7E-38 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A21D_RS16580 f66ebf73011fbf149f5dba7b24a2267c 102 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 58 77 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 Gene3D G3DSA:2.40.30.40 68 159 1.2E-32 T 28-03-2018 IPR023367 Peptidase M42, domain 2 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 Gene3D G3DSA:3.40.630.10 166 352 2.8E-41 T 28-03-2018 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 Pfam PF05343 M42 glutamyl aminopeptidase 46 335 5.2E-112 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 PIRSF PIRSF001123 2 354 1.3E-150 T 28-03-2018 IPR008007 Peptidase M42 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 SUPERFAMILY SSF101821 69 178 1.47E-31 T 28-03-2018 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 SUPERFAMILY SSF53187 170 347 1.23E-68 T 28-03-2018 A21D_RS14280 09a67d228931182ea288f55af6b02943 355 SUPERFAMILY SSF53187 4 79 1.23E-68 T 28-03-2018 A21D_RS12820 1d7c5db3fa5aa83ee2f9a530e7696d4f 567 Gene3D G3DSA:3.40.50.300 206 468 1.2E-10 T 28-03-2018 A21D_RS12820 1d7c5db3fa5aa83ee2f9a530e7696d4f 567 Pfam PF09818 Predicted ATPase of the ABC class 2 438 1.8E-181 T 28-03-2018 IPR019195 ABC transporter, ATPase, putative A21D_RS12820 1d7c5db3fa5aa83ee2f9a530e7696d4f 567 SUPERFAMILY SSF52540 241 416 1.91E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02430 d56ca8211846ee5afdaab3eb40d0e312 389 SUPERFAMILY SSF51905 4 220 1.99E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02430 d56ca8211846ee5afdaab3eb40d0e312 389 SUPERFAMILY SSF51905 315 380 1.99E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02430 d56ca8211846ee5afdaab3eb40d0e312 389 Gene3D G3DSA:3.50.50.60 2 387 8.7E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02430 d56ca8211846ee5afdaab3eb40d0e312 389 Pfam PF01266 FAD dependent oxidoreductase 6 352 1.4E-50 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A21D_RS05255 3728f2e0c202df171653d83138eeced6 162 SUPERFAMILY SSF55804 9 160 2.75E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS05255 3728f2e0c202df171653d83138eeced6 162 Gene3D G3DSA:3.40.930.10 8 162 4.8E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS05255 3728f2e0c202df171653d83138eeced6 162 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 160 8.2E-36 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 Gene3D G3DSA:1.10.10.10 5 90 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 1.8E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 1.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 1.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 1.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 SMART SM00418 13 96 1.2E-30 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS08355 81ecf77647afbf0c580c442542147a0c 114 SUPERFAMILY SSF46785 8 81 2.49E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14570 8cc4ed3bb215830ccd19f3283e2b624b 447 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 90 438 1.2E-93 T 28-03-2018 IPR014227 Sporulation integral membrane protein YtvI A21D_RS14570 8cc4ed3bb215830ccd19f3283e2b624b 447 Pfam PF01594 AI-2E family transporter 91 435 3.2E-56 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A21D_RS01270 7d1d64c992ca1e69f4602c92ccb13017 126 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 121 9.3E-45 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain A21D_RS01270 7d1d64c992ca1e69f4602c92ccb13017 126 SUPERFAMILY SSF53062 4 122 1.83E-35 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS01270 7d1d64c992ca1e69f4602c92ccb13017 126 Gene3D G3DSA:3.40.50.510 1 126 1.9E-38 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS01270 7d1d64c992ca1e69f4602c92ccb13017 126 Pfam PF03610 PTS system fructose IIA component 5 115 4.8E-31 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A21D_RS10725 8dceddb93969607b0d86becc444f4811 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 277 8.7E-59 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10725 8dceddb93969607b0d86becc444f4811 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 252 2.4E-23 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS10725 8dceddb93969607b0d86becc444f4811 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 278 3.6E-62 T 28-03-2018 IPR000150 Cof family GO:0016787 A21D_RS10725 8dceddb93969607b0d86becc444f4811 285 Gene3D G3DSA:3.40.50.1000 4 284 3.5E-36 T 28-03-2018 IPR023214 HAD-like domain A21D_RS10725 8dceddb93969607b0d86becc444f4811 285 SUPERFAMILY SSF56784 5 282 2.34E-56 T 28-03-2018 IPR023214 HAD-like domain A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 8 241 16.543 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 102 128 2.0E-32 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 2.0E-32 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 84 102 2.0E-32 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 153 181 2.0E-32 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 Pfam PF00902 Sec-independent protein translocase protein (TatC) 17 220 4.8E-51 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 14 225 3.0E-53 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A21D_RS16880 aa3903d1836917bf62207c3c4d3f8cc7 252 ProSitePatterns PS01218 TatC family signature. 153 172 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A21D_RS13095 ccf71a96cf29d2448186a17b36933d6e 161 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 88 1.2E-6 T 28-03-2018 IPR002831 Transcription regulator TrmB, N-terminal A21D_RS13095 ccf71a96cf29d2448186a17b36933d6e 161 PIRSF PIRSF006707 1 161 1.8E-34 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type A21D_RS13095 ccf71a96cf29d2448186a17b36933d6e 161 SUPERFAMILY SSF46785 8 151 2.66E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13095 ccf71a96cf29d2448186a17b36933d6e 161 Gene3D G3DSA:1.10.10.10 3 161 9.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03435 5c43449cb179b58acc2b7b024e7a2bd5 243 Gene3D G3DSA:3.30.240.20 86 154 3.6E-17 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS03435 5c43449cb179b58acc2b7b024e7a2bd5 243 Gene3D G3DSA:3.30.240.20 165 231 1.5E-11 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS03435 5c43449cb179b58acc2b7b024e7a2bd5 243 Pfam PF04239 Protein of unknown function (DUF421) 91 208 2.1E-27 T 28-03-2018 IPR007353 Protein of unknown function DUF421 A21D_RS04880 0a4c30d3f0f0b5af7884a479fc8141d1 412 Gene3D G3DSA:3.40.190.10 244 368 8.5E-13 T 28-03-2018 A21D_RS04880 0a4c30d3f0f0b5af7884a479fc8141d1 412 Gene3D G3DSA:3.40.190.10 35 243 7.7E-48 T 28-03-2018 A21D_RS04880 0a4c30d3f0f0b5af7884a479fc8141d1 412 SUPERFAMILY SSF53850 17 411 4.69E-88 T 28-03-2018 A21D_RS04880 0a4c30d3f0f0b5af7884a479fc8141d1 412 Pfam PF13416 Bacterial extracellular solute-binding protein 51 354 6.1E-50 T 28-03-2018 A21D_RS16265 e63931f43ab4bdbedcfb096ff5ad21cd 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 233 8.7E-47 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS16265 e63931f43ab4bdbedcfb096ff5ad21cd 245 SUPERFAMILY SSF51695 2 239 3.14E-75 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS16265 e63931f43ab4bdbedcfb096ff5ad21cd 245 Gene3D G3DSA:3.20.20.190 1 242 2.5E-71 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS04175 b9f5266468f1a78acff9c1bf4322d3a5 74 Pfam PF07872 Protein of unknown function (DUF1659) 7 51 5.5E-17 T 28-03-2018 IPR012454 Protein of unknown function DUF1659 A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 Gene3D G3DSA:2.40.50.140 1 79 2.5E-24 T 28-03-2018 A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 SUPERFAMILY SSF53335 72 457 2.16E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 Pfam PF01938 TRAM domain 9 64 1.0E-11 T 28-03-2018 IPR002792 TRAM domain A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 21 450 3.7E-178 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 Gene3D G3DSA:3.40.50.150 80 456 3.1E-65 T 28-03-2018 A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 260 457 4.9E-24 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 SUPERFAMILY SSF50249 4 65 9.71E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS11045 12bd88f0a7c921de93cb9fcbb272adab 460 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A21D_RS08805 ab620eb706d258a3485460aa573978f9 211 Pfam PF04239 Protein of unknown function (DUF421) 85 200 5.0E-26 T 28-03-2018 IPR007353 Protein of unknown function DUF421 A21D_RS08805 ab620eb706d258a3485460aa573978f9 211 Gene3D G3DSA:3.30.240.20 78 147 7.2E-21 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS08610 b73a76a9eb7d165f87c6cdd0743768c4 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 315 3.5E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08610 b73a76a9eb7d165f87c6cdd0743768c4 318 Gene3D G3DSA:1.10.3720.10 26 309 9.6E-37 T 28-03-2018 A21D_RS08610 b73a76a9eb7d165f87c6cdd0743768c4 318 SUPERFAMILY SSF161098 38 310 5.61E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS08610 b73a76a9eb7d165f87c6cdd0743768c4 318 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 314 1.2E-85 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 SUPERFAMILY SSF51735 9 338 1.46E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 327 1.0E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 Gene3D G3DSA:3.40.50.720 5 182 1.8E-33 T 28-03-2018 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 PRINTS PR01713 Nucleotide sugar epimerase signature 36 52 3.5E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 PRINTS PR01713 Nucleotide sugar epimerase signature 298 315 3.5E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 PRINTS PR01713 Nucleotide sugar epimerase signature 253 268 3.5E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 PRINTS PR01713 Nucleotide sugar epimerase signature 227 242 3.5E-27 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A21D_RS02610 d9ebd6deb80e9f72c09ef41823f5d7f8 340 Gene3D G3DSA:3.90.25.10 183 340 5.9E-34 T 28-03-2018 A21D_RS10435 d4657cd753b5c6a611192f4fbb750562 441 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 183 331 4.8E-35 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain A21D_RS10435 d4657cd753b5c6a611192f4fbb750562 441 Pfam PF17482 Phage tail sheath C-terminal domain 335 439 3.4E-21 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain A21D_RS10435 d4657cd753b5c6a611192f4fbb750562 441 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 94 182 4.9E-12 T 28-03-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain A21D_RS10435 d4657cd753b5c6a611192f4fbb750562 441 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 313 438 3.0E-31 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain A21D_RS10375 5c5d4dd4d5f6c07000625a2f94192f69 435 Pfam PF04466 Phage terminase large subunit 17 230 5.0E-79 T 28-03-2018 IPR035412 Phage terminase large subunit, N-terminal A21D_RS10375 5c5d4dd4d5f6c07000625a2f94192f69 435 Pfam PF17288 Terminase RNAseH like domain 267 408 4.2E-39 T 28-03-2018 IPR035413 Phage terminase large subunit, C-terminal A21D_RS10375 5c5d4dd4d5f6c07000625a2f94192f69 435 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 18 415 5.2E-99 T 28-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 A21D_RS01990 24421474dd631d3e0770962324ae7860 129 SUPERFAMILY SSF55331 2 128 8.59E-36 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily A21D_RS01990 24421474dd631d3e0770962324ae7860 129 Pfam PF14552 Tautomerase enzyme 38 118 4.1E-27 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A21D_RS01990 24421474dd631d3e0770962324ae7860 129 Gene3D G3DSA:3.30.429.10 1 129 1.7E-25 T 28-03-2018 A21D_RS18495 1ec6214be492b29e10f2d95abc23202b 145 Gene3D G3DSA:1.20.1500.10 9 118 1.6E-29 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS18495 1ec6214be492b29e10f2d95abc23202b 145 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 1.9E-22 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A21D_RS18495 1ec6214be492b29e10f2d95abc23202b 145 SUPERFAMILY SSF158622 4 124 1.06E-32 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS14055 a959e68d4509fe479ae9227584a26080 117 SUPERFAMILY SSF109635 4 88 1.7E-12 T 28-03-2018 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 Gene3D G3DSA:3.90.1820.10 276 441 1.4E-43 T 28-03-2018 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 Gene3D G3DSA:3.90.1820.10 1 275 2.3E-60 T 28-03-2018 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 SUPERFAMILY SSF56327 168 440 5.23E-93 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 Pfam PF02056 Family 4 glycosyl hydrolase 5 182 2.3E-63 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 416 4.9E-52 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 SUPERFAMILY SSF51735 3 163 2.78E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS07090 dbc8bb341455ebf632ee10e6114266ca 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 3.6E-56 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A21D_RS06015 814a1eaf0c3595a2f5e82d326ea851e3 338 Gene3D G3DSA:1.10.3470.10 16 333 1.8E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS06015 814a1eaf0c3595a2f5e82d326ea851e3 338 SUPERFAMILY SSF81345 17 331 6.93E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS06015 814a1eaf0c3595a2f5e82d326ea851e3 338 Pfam PF01032 FecCD transport family 33 330 1.6E-62 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Pfam PF08239 Bacterial SH3 domain 31 82 2.6E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 164 331 8.7E-43 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Gene3D G3DSA:3.40.630.40 159 340 1.1E-49 T 28-03-2018 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 SUPERFAMILY SSF53187 162 335 1.29E-47 T 28-03-2018 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 SMART SM00646 223 332 6.7E-20 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 SMART SM00287 22 85 4.3E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 SMART SM00287 90 147 1.7E-4 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Pfam PF06347 Bacterial SH3 domain 101 146 1.1E-5 T 28-03-2018 IPR010466 Protein of unknown function DUF1058 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Gene3D G3DSA:2.40.50.110 84 150 2.5E-10 T 28-03-2018 A21D_RS15345 32c108877fd34c96d9edf7714b274fe2 344 Gene3D G3DSA:2.40.50.110 12 83 1.5E-14 T 28-03-2018 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 355 4.5E-166 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 Gene3D G3DSA:3.30.420.40 4 181 2.2E-55 T 28-03-2018 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 PRINTS PR00471 Acetate kinase family signature 299 315 3.0E-14 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 PRINTS PR00471 Acetate kinase family signature 7 18 3.0E-14 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 PRINTS PR00471 Acetate kinase family signature 181 202 3.0E-14 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 PRINTS PR00471 Acetate kinase family signature 276 289 3.0E-14 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 Gene3D G3DSA:3.30.420.40 182 356 6.6E-44 T 28-03-2018 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 PIRSF PIRSF036458 3 358 2.5E-166 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 Pfam PF00871 Acetokinase family 7 355 4.0E-65 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 Hamap MF_00542 Probable butyrate kinase [buk]. 1 362 161.942 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 SUPERFAMILY SSF53067 119 350 7.02E-53 T 28-03-2018 A21D_RS16185 de6c7ee0409b784dbc5a701d5d061acd 362 SUPERFAMILY SSF53067 5 173 1.99E-67 T 28-03-2018 A21D_RS10680 59affb351854e3672ea1a9ba907113ad 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 304 1.3E-52 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A21D_RS10680 59affb351854e3672ea1a9ba907113ad 311 Gene3D G3DSA:1.10.3470.10 27 310 1.3E-39 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS02750 c3c4a92f542095af8aa512436eda4dae 493 SUPERFAMILY SSF53850 7 490 2.6E-75 T 28-03-2018 A21D_RS02750 c3c4a92f542095af8aa512436eda4dae 493 Pfam PF13416 Bacterial extracellular solute-binding protein 32 346 3.8E-16 T 28-03-2018 A21D_RS02750 c3c4a92f542095af8aa512436eda4dae 493 Gene3D G3DSA:3.40.190.10 143 492 5.3E-40 T 28-03-2018 A21D_RS12410 c13ef30b4bc371b901d4dc0b8ac618d6 428 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 423 6.7E-149 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS12410 c13ef30b4bc371b901d4dc0b8ac618d6 428 PIRSF PIRSF006351 1 428 2.1E-147 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS12410 c13ef30b4bc371b901d4dc0b8ac618d6 428 Pfam PF02378 Phosphotransferase system, EIIC 29 348 9.8E-64 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS12410 c13ef30b4bc371b901d4dc0b8ac618d6 428 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 423 6.7E-149 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS11735 47b23add901eb53fcb61b76e742e12de 258 Gene3D G3DSA:3.40.50.300 1 238 2.2E-62 T 28-03-2018 A21D_RS11735 47b23add901eb53fcb61b76e742e12de 258 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS11735 47b23add901eb53fcb61b76e742e12de 258 SMART SM00382 33 220 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS11735 47b23add901eb53fcb61b76e742e12de 258 Pfam PF00005 ABC transporter 24 172 4.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS11735 47b23add901eb53fcb61b76e742e12de 258 SUPERFAMILY SSF52540 3 226 2.54E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05510 df783d6af34f211ad14d02742240485a 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 756 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 PIRSF PIRSF000382 3 761 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 Gene3D G3DSA:3.20.20.210 4 387 1.7E-123 T 28-03-2018 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 756 33.525 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 312 2.8E-118 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 SUPERFAMILY SSF51726 7 382 1.27E-97 T 28-03-2018 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 429 751 9.6E-138 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 Gene3D G3DSA:3.20.20.210 388 757 3.6E-116 T 28-03-2018 A21D_RS05510 df783d6af34f211ad14d02742240485a 762 SUPERFAMILY SSF51726 394 755 4.97E-106 T 28-03-2018 A21D_RS14235 41b37330558d1f66633b25de9539f323 536 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 372 516 3.8E-26 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A21D_RS14235 41b37330558d1f66633b25de9539f323 536 Pfam PF01943 Polysaccharide biosynthesis protein 4 317 2.6E-38 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A21D_RS14235 41b37330558d1f66633b25de9539f323 536 Gene3D G3DSA:1.10.287.70 8 529 0.13 T 28-03-2018 A21D_RS14235 41b37330558d1f66633b25de9539f323 536 PIRSF PIRSF038958 1 535 2.2E-119 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A21D_RS11175 fbfeea19e6d5a2da08d63db520627b36 298 Gene3D G3DSA:1.20.1260.10 1 199 2.6E-48 T 28-03-2018 IPR012347 Ferritin-related A21D_RS11175 fbfeea19e6d5a2da08d63db520627b36 298 Pfam PF05067 Manganese containing catalase 1 296 5.6E-86 T 28-03-2018 IPR007760 Manganese catalase A21D_RS11175 fbfeea19e6d5a2da08d63db520627b36 298 SUPERFAMILY SSF47240 1 295 7.16E-90 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS14050 ad338e78b4ceee349355f4343257a80f 323 Pfam PF03576 Peptidase family S58 5 311 2.2E-57 T 28-03-2018 IPR005321 Peptidase S58, DmpA A21D_RS14050 ad338e78b4ceee349355f4343257a80f 323 SUPERFAMILY SSF56266 4 317 7.06E-68 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A21D_RS14050 ad338e78b4ceee349355f4343257a80f 323 Gene3D G3DSA:3.60.70.12 2 321 7.1E-103 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A21D_RS01830 55251f78da93c3976e72970ae4f01ccf 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A21D_RS01830 55251f78da93c3976e72970ae4f01ccf 258 Gene3D G3DSA:1.10.12.10 219 255 2.0E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS01830 55251f78da93c3976e72970ae4f01ccf 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 256 1.0E-64 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS01830 55251f78da93c3976e72970ae4f01ccf 258 Gene3D G3DSA:3.90.226.10 1 218 3.3E-71 T 28-03-2018 A21D_RS01830 55251f78da93c3976e72970ae4f01ccf 258 SUPERFAMILY SSF52096 2 255 1.13E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS10545 f4befdde6eb474d9d7c399b3d12e231c 155 Pfam PF09406 Protein of unknown function (DUF2004) 71 152 8.0E-13 T 28-03-2018 IPR018546 Protein of unknown function DUF2004 A21D_RS10495 85a30778d21bd806b4d138a83349481e 143 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 133 1.4E-25 T 28-03-2018 IPR006480 Bacteriophage holin family A21D_RS10495 85a30778d21bd806b4d138a83349481e 143 Pfam PF05105 Bacteriophage holin family 12 126 2.9E-36 T 28-03-2018 IPR006480 Bacteriophage holin family A21D_RS18860 323defcef8444bed0ea7bca4331dfb10 284 Gene3D G3DSA:3.30.240.20 82 151 1.1E-22 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS18860 323defcef8444bed0ea7bca4331dfb10 284 Gene3D G3DSA:3.30.240.20 162 226 1.6E-15 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A21D_RS18860 323defcef8444bed0ea7bca4331dfb10 284 Pfam PF04239 Protein of unknown function (DUF421) 89 204 2.1E-29 T 28-03-2018 IPR007353 Protein of unknown function DUF421 A21D_RS18860 323defcef8444bed0ea7bca4331dfb10 284 Pfam PF07870 Protein of unknown function (DUF1657) 238 284 9.4E-16 T 28-03-2018 IPR012452 Protein of unknown function DUF1657 A21D_RS02945 4b7fbf3b44b851579b7278a922458f45 205 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 199 15.8 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS02945 4b7fbf3b44b851579b7278a922458f45 205 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 190 4.3E-39 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS02945 4b7fbf3b44b851579b7278a922458f45 205 SMART SM01207 8 191 1.7E-43 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 284 3.0E-62 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 282 1.1E-77 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 Pfam PF05175 Methyltransferase small domain 118 201 8.4E-16 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 Gene3D G3DSA:3.40.50.150 84 288 7.5E-40 T 28-03-2018 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 Gene3D G3DSA:1.10.8.10 5 83 1.9E-14 T 28-03-2018 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 286 35.624 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 SUPERFAMILY SSF53335 8 258 3.95E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS04650 e1ece1034ef6a9ec92fca0d1f8d5c472 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 189 195 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A21D_RS11595 3d183ad887173da84ebef7d161e68566 433 Pfam PF03553 Na+/H+ antiporter family 143 427 1.2E-60 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS11595 3d183ad887173da84ebef7d161e68566 433 Pfam PF13726 Na+-H+ antiporter family 5 89 8.5E-24 T 28-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal A21D_RS08235 536bfba20644531a55bb89e0e845c348 288 Pfam PF06007 Phosphonate metabolism protein PhnJ 4 275 8.4E-141 T 28-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS08235 536bfba20644531a55bb89e0e845c348 288 PIRSF PIRSF011468 1 286 4.9E-143 T 28-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A21D_RS01680 fa68e2ac80ab94ff631998d5314a00e2 146 Pfam PF02566 OsmC-like protein 39 142 2.4E-19 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS01680 fa68e2ac80ab94ff631998d5314a00e2 146 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 4.9E-64 T 28-03-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes A21D_RS01680 fa68e2ac80ab94ff631998d5314a00e2 146 Gene3D G3DSA:3.30.300.20 1 146 1.2E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A21D_RS01680 fa68e2ac80ab94ff631998d5314a00e2 146 SUPERFAMILY SSF82784 2 142 4.45E-33 T 28-03-2018 IPR003718 OsmC/Ohr family A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 Gene3D G3DSA:1.10.10.10 109 176 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 Pfam PF08281 Sigma-70, region 4 111 162 5.0E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 166 1.1E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 TIGRFAM TIGR02954 Sig70_famx3: RNA polymerase sigma-70 factor, TIGR02954 family 1 166 2.9E-63 T 28-03-2018 IPR014300 RNA polymerase sigma-V type A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 SUPERFAMILY SSF88946 1 100 5.49E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 SUPERFAMILY SSF88659 104 166 7.48E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 Gene3D G3DSA:1.10.1740.10 1 108 4.7E-18 T 28-03-2018 A21D_RS09250 781fe1d7c37dec82303a887f070eda0d 181 Pfam PF04542 Sigma-70 region 2 25 88 3.8E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS13790 b4fbf7bbf8dfef123144672ad5131d93 139 Gene3D G3DSA:3.40.50.10600 14 139 6.0E-14 T 28-03-2018 A21D_RS13790 b4fbf7bbf8dfef123144672ad5131d93 139 Pfam PF11964 SpoIIAA-like 35 137 3.8E-11 T 28-03-2018 IPR021866 SpoIIAA-like A21D_RS13790 b4fbf7bbf8dfef123144672ad5131d93 139 SUPERFAMILY SSF52091 21 137 3.92E-23 T 28-03-2018 IPR002645 STAS domain A21D_RS08820 14b3a7167ccf8d0632b86ee2d3e7c7ce 347 Gene3D G3DSA:1.10.620.20 4 321 1.6E-76 T 28-03-2018 A21D_RS08820 14b3a7167ccf8d0632b86ee2d3e7c7ce 347 SUPERFAMILY SSF47240 24 347 1.37E-85 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS08820 14b3a7167ccf8d0632b86ee2d3e7c7ce 347 PIRSF PIRSF000355 2 347 1.7E-111 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS08820 14b3a7167ccf8d0632b86ee2d3e7c7ce 347 Pfam PF00268 Ribonucleotide reductase, small chain 32 309 1.3E-69 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A21D_RS10610 b4faa9edb779699ed022217e521950bc 473 Pfam PF02554 Carbon starvation protein CstA 163 288 5.1E-14 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A21D_RS10610 b4faa9edb779699ed022217e521950bc 473 Pfam PF02554 Carbon starvation protein CstA 3 145 2.4E-34 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A21D_RS10610 b4faa9edb779699ed022217e521950bc 473 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 316 426 8.7E-21 T 28-03-2018 IPR025299 CstA, C-terminal domain A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 SUPERFAMILY SSF109998 26 165 4.32E-14 T 28-03-2018 IPR027304 Trigger factor/SurA domain A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 Pfam PF13616 PPIC-type PPIASE domain 130 226 6.4E-26 T 28-03-2018 A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 SUPERFAMILY SSF54534 127 225 1.24E-33 T 28-03-2018 A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 165 185 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 285 21.381 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 A21D_RS13075 47f3c433f8ba18ebe9b3acd64bafcb88 296 Gene3D G3DSA:3.10.50.40 127 253 1.1E-38 T 28-03-2018 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Gene3D G3DSA:3.40.1060.10 242 374 3.5E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Gene3D G3DSA:3.30.499.10 375 586 5.7E-66 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Pfam PF00330 Aconitase family (aconitate hydratase) 74 572 4.0E-177 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Gene3D G3DSA:3.20.19.10 664 902 2.6E-89 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 900 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Gene3D G3DSA:3.30.499.10 43 241 5.0E-71 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 Pfam PF00694 Aconitase C-terminal domain 702 829 7.7E-45 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 295 308 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 219 234 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 147 160 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 281 294 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 503 516 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 441 452 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 205 218 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 171 179 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 PRINTS PR00415 Aconitase family signature 375 389 4.9E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 SUPERFAMILY SSF52016 641 899 1.1E-84 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 ProSitePatterns PS01244 Aconitase family signature 2. 503 516 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 SUPERFAMILY SSF53732 5 637 2.22E-223 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A21D_RS17115 b737c46d117092ef5b98d2312aa71e20 904 ProSitePatterns PS00450 Aconitase family signature 1. 437 453 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A21D_RS09320 b57a202c8866688e29f7005446daaa3e 375 Gene3D G3DSA:3.40.640.10 13 257 7.9E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS09320 b57a202c8866688e29f7005446daaa3e 375 SUPERFAMILY SSF53383 57 373 8.73E-36 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS09320 b57a202c8866688e29f7005446daaa3e 375 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 62 275 4.7E-16 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 SUPERFAMILY SSF53187 2 198 8.46E-68 T 28-03-2018 A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 SUPERFAMILY SSF53187 368 452 8.46E-68 T 28-03-2018 A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 Pfam PF07687 Peptidase dimerisation domain 195 353 3.8E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 SUPERFAMILY SSF55031 198 244 3.45E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 SUPERFAMILY SSF55031 299 359 3.45E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 Pfam PF01546 Peptidase family M20/M25/M40 84 449 8.9E-40 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 Gene3D G3DSA:3.30.70.360 202 364 1.0E-53 T 28-03-2018 A21D_RS12925 4eee03152288c940dbbe26704d9a0de4 455 Gene3D G3DSA:3.40.630.10 5 201 1.7E-43 T 28-03-2018 A21D_RS10410 9ee3d37954ef0724823413d980259d56 126 SUPERFAMILY SSF116915 2 124 1.44E-41 T 28-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG A21D_RS10410 9ee3d37954ef0724823413d980259d56 126 Gene3D G3DSA:1.10.3230.10 1 126 2.3E-34 T 28-03-2018 A21D_RS10410 9ee3d37954ef0724823413d980259d56 126 Pfam PF11436 Protein of unknown function (DUF3199) 3 124 2.4E-42 T 28-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG A21D_RS04210 bb7f1bcb4e4d7414c8262ba623f437ce 397 SUPERFAMILY SSF53756 74 385 1.88E-28 T 28-03-2018 A21D_RS04210 bb7f1bcb4e4d7414c8262ba623f437ce 397 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 23 383 1.7E-78 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 SUPERFAMILY SSF55604 453 527 1.07E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 Gene3D G3DSA:3.30.1360.60 451 527 6.0E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 466 483 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 Pfam PF02378 Phosphotransferase system, EIIC 13 350 3.8E-67 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 409 513 3.8E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A21D_RS08930 85cf972cf0d8a73f01baf1cd2fae5a34 533 Pfam PF00367 phosphotransferase system, EIIB 457 488 2.4E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A21D_RS00860 5fc8b88da3e9cc233bcc759cb1499db8 178 Gene3D G3DSA:1.20.58.300 17 151 1.5E-22 T 28-03-2018 A21D_RS00860 5fc8b88da3e9cc233bcc759cb1499db8 178 SUPERFAMILY SSF140566 19 150 4.18E-15 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A21D_RS00860 5fc8b88da3e9cc233bcc759cb1499db8 178 Pfam PF05130 FlgN protein 18 164 3.1E-23 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A21D_RS00265 c682a70386dbddfd90807c181908301c 118 SUPERFAMILY SSF110455 7 111 7.59E-25 T 28-03-2018 A21D_RS00265 c682a70386dbddfd90807c181908301c 118 Gene3D G3DSA:3.40.1360.20 3 115 6.8E-14 T 28-03-2018 A21D_RS12585 c98f9b483f7857db69ad23c6bf3e8ce4 327 Pfam PF03060 Nitronate monooxygenase 58 307 6.1E-26 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A21D_RS12585 c98f9b483f7857db69ad23c6bf3e8ce4 327 Gene3D G3DSA:3.20.20.70 7 327 2.6E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS12585 c98f9b483f7857db69ad23c6bf3e8ce4 327 SUPERFAMILY SSF51412 13 306 3.82E-55 T 28-03-2018 A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 SUPERFAMILY SSF55594 1 87 4.32E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.5E-29 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.9E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 Gene3D G3DSA:3.30.1340.10 1 87 1.5E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.9E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.9E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS13980 23c8583b5e2552fe21371dac650fbc03 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.9E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A21D_RS08815 a9f4a8ecab7bffd215cb0ba51a1a7a84 160 Pfam PF00258 Flavodoxin 9 110 1.1E-7 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A21D_RS08815 a9f4a8ecab7bffd215cb0ba51a1a7a84 160 SUPERFAMILY SSF52218 6 141 1.15E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS08815 a9f4a8ecab7bffd215cb0ba51a1a7a84 160 TIGRFAM TIGR01754 flav_RNR: putative ribonucleotide reductase-associated flavodoxin 5 141 2.2E-54 T 28-03-2018 IPR010088 Ribonucleotide reductase-associated flavodoxin, putative A21D_RS08815 a9f4a8ecab7bffd215cb0ba51a1a7a84 160 Gene3D G3DSA:3.40.50.360 1 158 1.3E-19 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS10020 9622b603b35c6b0d2855e61125ebb15e 94 Gene3D G3DSA:1.10.1220.10 6 58 7.0E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 Gene3D G3DSA:3.30.750.24 386 480 3.1E-12 T 28-03-2018 IPR002645 STAS domain A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 Pfam PF01740 STAS domain 400 473 6.0E-5 T 28-03-2018 IPR002645 STAS domain A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 SUPERFAMILY SSF52091 397 473 3.34E-10 T 28-03-2018 IPR002645 STAS domain A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 Pfam PF00916 Sulfate permease family 152 355 1.0E-32 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 Pfam PF00916 Sulfate permease family 15 142 3.5E-28 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A21D_RS01605 6ad35b1197aeb458de649b45533574b0 486 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 28-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 A21D_RS05815 db614c317464acf2e7de3e4607e013bb 336 Pfam PF01032 FecCD transport family 20 334 9.4E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS05815 db614c317464acf2e7de3e4607e013bb 336 Gene3D G3DSA:1.10.3470.10 6 336 4.0E-63 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS05815 db614c317464acf2e7de3e4607e013bb 336 SUPERFAMILY SSF81345 6 334 1.44E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS16790 22541b09ae509299347d7131c1e9c3c6 135 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 102 1.4E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A21D_RS16790 22541b09ae509299347d7131c1e9c3c6 135 Gene3D G3DSA:3.40.140.10 1 135 9.1E-52 T 28-03-2018 A21D_RS16790 22541b09ae509299347d7131c1e9c3c6 135 SUPERFAMILY SSF53927 4 131 1.84E-48 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS16790 22541b09ae509299347d7131c1e9c3c6 135 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 131 1.6E-47 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 A21D_RS16790 22541b09ae509299347d7131c1e9c3c6 135 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 94 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A21D_RS02890 1469daded9555835077594adb299a387 323 SMART SM00450 117 218 1.1E-19 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02890 1469daded9555835077594adb299a387 323 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 269 40.503 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 A21D_RS02890 1469daded9555835077594adb299a387 323 Pfam PF00581 Rhodanese-like domain 118 212 4.3E-10 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02890 1469daded9555835077594adb299a387 323 Pfam PF12368 Rhodanase C-terminal 224 290 1.5E-13 T 28-03-2018 IPR022111 Rhodanase, C-terminal A21D_RS02890 1469daded9555835077594adb299a387 323 Gene3D G3DSA:3.40.250.10 111 222 1.4E-26 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS02890 1469daded9555835077594adb299a387 323 SUPERFAMILY SSF52821 90 246 1.57E-36 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS17110 48f9be2a9a68ebf0e46708809f9343c0 193 ProSitePatterns PS00194 Thioredoxin family active site. 85 103 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A21D_RS17110 48f9be2a9a68ebf0e46708809f9343c0 193 Gene3D G3DSA:3.40.30.10 42 193 2.0E-40 T 28-03-2018 A21D_RS17110 48f9be2a9a68ebf0e46708809f9343c0 193 SUPERFAMILY SSF52833 53 190 5.4E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS17110 48f9be2a9a68ebf0e46708809f9343c0 193 Pfam PF00578 AhpC/TSA family 57 175 3.0E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS11575 0da3f666b03388566caad1e618de13c9 188 SUPERFAMILY SSF52980 4 186 2.47E-41 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A21D_RS11575 0da3f666b03388566caad1e618de13c9 188 Gene3D G3DSA:3.90.1570.10 1 186 2.4E-46 T 28-03-2018 A21D_RS11575 0da3f666b03388566caad1e618de13c9 188 Pfam PF05685 Putative restriction endonuclease 12 182 1.3E-31 T 28-03-2018 IPR008538 Domain of unknown function DUF820 A21D_RS04055 b80f77de11d09f941dd0edf0d9877e66 225 Pfam PF08241 Methyltransferase domain 51 142 2.6E-25 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS04055 b80f77de11d09f941dd0edf0d9877e66 225 SUPERFAMILY SSF53335 8 199 1.67E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS04055 b80f77de11d09f941dd0edf0d9877e66 225 Gene3D G3DSA:3.40.50.150 25 214 5.8E-34 T 28-03-2018 A21D_RS13895 9d8643d08bab69f29e6ed1fff649d674 150 Pfam PF01934 Protein of unknown function DUF86 24 127 6.9E-20 T 28-03-2018 IPR008201 Protein of unknown function DUF86 A21D_RS13895 9d8643d08bab69f29e6ed1fff649d674 150 Gene3D G3DSA:1.20.120.580 1 144 3.2E-28 T 28-03-2018 IPR008201 Protein of unknown function DUF86 A21D_RS03185 b70fa661747361c9e40651a27a6e2164 186 Pfam PF00881 Nitroreductase family 14 164 6.4E-28 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A21D_RS03185 b70fa661747361c9e40651a27a6e2164 186 SUPERFAMILY SSF55469 7 181 1.23E-37 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A21D_RS03185 b70fa661747361c9e40651a27a6e2164 186 Gene3D G3DSA:3.40.109.10 2 186 6.4E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 Gene3D G3DSA:1.10.10.10 130 231 5.0E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 SMART SM00448 4 114 1.8E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 Pfam PF00072 Response regulator receiver domain 6 115 1.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 2.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 SMART SM00862 153 229 8.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 Gene3D G3DSA:3.40.50.2300 1 129 1.2E-36 T 28-03-2018 A21D_RS03495 77255c7a576f3902f0040780f2d11849 231 SUPERFAMILY SSF52172 1 188 2.78E-42 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 SUPERFAMILY SSF50249 7 84 4.71E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.7E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 2.0E-31 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 Gene3D G3DSA:2.40.50.140 7 84 5.8E-32 T 28-03-2018 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 2.7E-34 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 Pfam PF00366 Ribosomal protein S17 12 79 7.8E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06330 e72a06f0ab0bd48ab301544c7aa75ea9 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.355 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS18335 932f4c457b1dcc37550741e743d5a9c5 141 Hamap MF_01197 Cell division protein SepF [sepF]. 1 133 19.626 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 A21D_RS18335 932f4c457b1dcc37550741e743d5a9c5 141 Pfam PF04472 Cell division protein SepF 54 125 2.7E-29 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 88 101 1.1E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 120 133 1.1E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 119 1.1E-16 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 158 1.0E-48 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 SUPERFAMILY SSF51230 84 158 5.37E-22 T 28-03-2018 IPR011053 Single hybrid motif A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 Pfam PF00364 Biotin-requiring enzyme 84 157 1.0E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A21D_RS16090 da07d01e7bbe465551a1b596462628f1 161 Gene3D G3DSA:2.40.50.100 39 160 5.8E-15 T 28-03-2018 A21D_RS09385 289395195edde498b9388b7db8208a52 549 Pfam PF01546 Peptidase family M20/M25/M40 83 473 3.6E-11 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS09385 289395195edde498b9388b7db8208a52 549 Gene3D G3DSA:3.40.630.10 4 539 6.5E-33 T 28-03-2018 A21D_RS09385 289395195edde498b9388b7db8208a52 549 SUPERFAMILY SSF53187 434 542 3.83E-31 T 28-03-2018 A21D_RS09385 289395195edde498b9388b7db8208a52 549 SUPERFAMILY SSF53187 4 98 3.83E-31 T 28-03-2018 A21D_RS09385 289395195edde498b9388b7db8208a52 549 SUPERFAMILY SSF53187 132 237 3.83E-31 T 28-03-2018 A21D_RS09385 289395195edde498b9388b7db8208a52 549 PIRSF PIRSF010386 1 549 1.9E-187 T 28-03-2018 IPR012166 Uncharacterised protein family RocB A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 SUPERFAMILY SSF55909 3 410 8.64E-132 T 28-03-2018 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 Hamap MF_00242 Arginine deiminase [arcA]. 2 410 47.215 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PIRSF PIRSF006356 1 410 1.9E-162 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 Gene3D G3DSA:3.75.10.10 4 408 4.9E-101 T 28-03-2018 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 TIGRFAM TIGR01078 arcA: arginine deiminase 5 410 7.7E-170 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 Pfam PF02274 Amidinotransferase 19 407 7.4E-112 T 28-03-2018 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS07945 a7b44c8d7b81d779273716a6c2499335 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 3.6E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A21D_RS02545 db0832a080d22dfb13af5c1f8605d9c7 282 SUPERFAMILY SSF52540 4 227 1.59E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02545 db0832a080d22dfb13af5c1f8605d9c7 282 Pfam PF00005 ABC transporter 20 161 4.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS02545 db0832a080d22dfb13af5c1f8605d9c7 282 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02545 db0832a080d22dfb13af5c1f8605d9c7 282 Gene3D G3DSA:3.40.50.300 1 269 1.1E-64 T 28-03-2018 A21D_RS02545 db0832a080d22dfb13af5c1f8605d9c7 282 SMART SM00382 29 217 5.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS13370 122f17597f15227d9a7a2f502c00e2d9 68 Pfam PF12758 Protein of unknown function (DUF3813) 5 64 3.5E-14 T 28-03-2018 IPR024217 Protein of unknown function DUF3813 A21D_RS07190 67818a566f738039753aaa44a8e25c7c 315 Pfam PF14175 YaaC-like Protein 8 307 2.3E-83 T 28-03-2018 IPR026988 YaaC-like protein A21D_RS09875 9697a6e9f58d3a06ce306bb2e975830c 187 Pfam PF13302 Acetyltransferase (GNAT) domain 17 159 6.6E-29 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS09875 9697a6e9f58d3a06ce306bb2e975830c 187 Gene3D G3DSA:3.40.630.30 9 186 8.6E-26 T 28-03-2018 A21D_RS09875 9697a6e9f58d3a06ce306bb2e975830c 187 SUPERFAMILY SSF55729 10 185 3.96E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS03760 40f84639e1b7fd9cdcdd2b46b3aaefc3 121 Pfam PF13789 Domain of unknown function (DUF4181) 13 114 4.0E-15 T 28-03-2018 IPR025441 Protein of unknown function DUF4181 A21D_RS02650 fcd378e4a27bda4cb65ffa35125546ec 211 Pfam PF02397 Bacterial sugar transferase 6 183 6.3E-60 T 28-03-2018 IPR003362 Bacterial sugar transferase A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Pfam PF03413 Peptidase propeptide and YPEB domain 152 235 9.6E-9 T 28-03-2018 IPR025711 PepSY domain A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 397 545 4.2E-49 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 96 139 1.1E-9 T 28-03-2018 IPR011096 FTP domain A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 349 369 1.4E-22 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 472 488 1.4E-22 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 406 417 1.4E-22 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 385 401 1.4E-22 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 246 393 4.4E-41 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Gene3D G3DSA:1.10.390.10 399 546 1.3E-50 T 28-03-2018 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 Gene3D G3DSA:3.10.170.10 245 398 2.9E-41 T 28-03-2018 A21D_RS02830 42935faa37a7a2a7216f5f00747d67e7 546 SUPERFAMILY SSF55486 246 545 3.85E-95 T 28-03-2018 A21D_RS03105 d8baa036ac445a1993b50ca39025e0a8 178 SMART SM00471 21 127 3.4E-6 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS03105 d8baa036ac445a1993b50ca39025e0a8 178 Pfam PF13328 HD domain 5 123 4.2E-18 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS03105 d8baa036ac445a1993b50ca39025e0a8 178 SUPERFAMILY SSF109604 4 132 9.77E-34 T 28-03-2018 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 Gene3D G3DSA:3.65.10.10 223 419 1.2E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.1E-111 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.858 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 8.4E-176 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 SUPERFAMILY SSF55205 1 418 9.97E-141 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A21D_RS04515 c4965ed9a11042f68a41db5c4a466c10 442 Gene3D G3DSA:3.65.10.10 21 222 6.0E-48 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 Pfam PF01381 Helix-turn-helix 8 59 3.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 Gene3D G3DSA:1.10.260.40 2 67 2.0E-10 T 28-03-2018 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 Gene3D G3DSA:1.25.40.10 68 195 1.0E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 Gene3D G3DSA:1.25.40.10 196 267 0.0013 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 Gene3D G3DSA:1.25.40.10 268 421 0.033 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 SUPERFAMILY SSF48452 149 362 4.41E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 SMART SM00530 7 61 1.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS09810 106256ababa22b6f95a9932ad3a9089f 422 SUPERFAMILY SSF47413 2 58 2.56E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS18075 2c094859b5e24c026ce2b8ea75837a3b 323 Pfam PF00665 Integrase core domain 161 265 4.2E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A21D_RS18075 2c094859b5e24c026ce2b8ea75837a3b 323 Gene3D G3DSA:3.30.420.10 148 318 2.6E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18075 2c094859b5e24c026ce2b8ea75837a3b 323 SUPERFAMILY SSF53098 160 309 1.18E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS18075 2c094859b5e24c026ce2b8ea75837a3b 323 Gene3D G3DSA:1.10.10.60 3 47 1.4E-8 T 28-03-2018 A21D_RS02625 a78eeb62f8ee15eb07874fde3b3e3294 370 Pfam PF13439 Glycosyltransferase Family 4 14 177 2.5E-11 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A21D_RS02625 a78eeb62f8ee15eb07874fde3b3e3294 370 SUPERFAMILY SSF53756 3 364 1.14E-55 T 28-03-2018 A21D_RS02625 a78eeb62f8ee15eb07874fde3b3e3294 370 Gene3D G3DSA:3.40.50.2000 25 184 2.4E-5 T 28-03-2018 A21D_RS02625 a78eeb62f8ee15eb07874fde3b3e3294 370 Pfam PF00534 Glycosyl transferases group 1 186 303 2.9E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A21D_RS02625 a78eeb62f8ee15eb07874fde3b3e3294 370 Gene3D G3DSA:3.40.50.2000 185 368 1.5E-30 T 28-03-2018 A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 Gene3D G3DSA:3.60.21.10 72 273 6.2E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 Gene3D G3DSA:3.60.21.10 1 71 2.3E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 SUPERFAMILY SSF56300 1 320 1.5E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 249 7.7E-47 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 Pfam PF00149 Calcineurin-like phosphoesterase 1 97 3.5E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS18965 05b0958432b017c3dcfa1d7ac4048e08 393 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 271 357 5.7E-13 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 SUPERFAMILY SSF46689 3 73 2.67E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 1.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 Gene3D G3DSA:1.10.10.60 2 58 4.8E-13 T 28-03-2018 A21D_RS07080 0c2dda0a6b0c8dea761fe9d26a19ea12 194 Gene3D G3DSA:1.10.357.10 59 194 1.3E-5 T 28-03-2018 A21D_RS11765 491b63729dac4dacfa3079923b5f38ac 152 Gene3D G3DSA:1.10.10.10 2 90 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11765 491b63729dac4dacfa3079923b5f38ac 152 SUPERFAMILY SSF46785 10 139 7.39E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11765 491b63729dac4dacfa3079923b5f38ac 152 Pfam PF01475 Ferric uptake regulator family 18 135 2.2E-39 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A21D_RS15885 39e00288d157c33c114d6b06842134c1 185 PIRSF PIRSF006806 1 183 1.1E-44 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A21D_RS15885 39e00288d157c33c114d6b06842134c1 185 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 180 9.3E-39 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A21D_RS15885 39e00288d157c33c114d6b06842134c1 185 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 180 7.4E-50 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A21D_RS15885 39e00288d157c33c114d6b06842134c1 185 SUPERFAMILY SSF100950 2 184 3.35E-44 T 28-03-2018 A21D_RS15885 39e00288d157c33c114d6b06842134c1 185 Gene3D G3DSA:3.40.50.10420 1 185 3.3E-47 T 28-03-2018 A21D_RS06920 48d719cf0d7adf99fbe2ab3ef28ebd39 177 SUPERFAMILY SSF52499 5 169 6.54E-42 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS06920 48d719cf0d7adf99fbe2ab3ef28ebd39 177 Pfam PF00857 Isochorismatase family 8 165 2.2E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS06920 48d719cf0d7adf99fbe2ab3ef28ebd39 177 Gene3D G3DSA:3.40.50.850 3 175 1.2E-33 T 28-03-2018 A21D_RS13000 16b7d5b35f7ba2103d56f2dc2c6b3922 65 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A21D_RS13000 16b7d5b35f7ba2103d56f2dc2c6b3922 65 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 40 54 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A21D_RS13000 16b7d5b35f7ba2103d56f2dc2c6b3922 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 61 3.9E-23 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A21D_RS00435 72ee0707b0d2830e4e66ce5c4e3318ea 256 SUPERFAMILY SSF52540 5 226 2.0E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00435 72ee0707b0d2830e4e66ce5c4e3318ea 256 SMART SM00382 34 222 4.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00435 72ee0707b0d2830e4e66ce5c4e3318ea 256 Gene3D G3DSA:3.40.50.300 1 232 7.5E-64 T 28-03-2018 A21D_RS00435 72ee0707b0d2830e4e66ce5c4e3318ea 256 Pfam PF00005 ABC transporter 25 173 9.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS13700 8a048be01b73d696fa80768d94fe28d4 225 Gene3D G3DSA:1.20.1170.10 2 178 3.9E-4 T 28-03-2018 A21D_RS10395 bc0c05d59908895d0f4b9a1d8295f357 399 Gene3D G3DSA:1.20.5.30 345 372 0.09 T 28-03-2018 A21D_RS10395 bc0c05d59908895d0f4b9a1d8295f357 399 Pfam PF14550 Putative phage serine protease XkdF 43 156 4.0E-47 T 28-03-2018 IPR027924 Phage-like element PBSX protein, XkdF A21D_RS14965 0f5b0501ce62d971491914ee3fe7cf13 339 Gene3D G3DSA:3.40.50.720 1 245 1.6E-63 T 28-03-2018 A21D_RS14965 0f5b0501ce62d971491914ee3fe7cf13 339 Pfam PF00899 ThiF family 5 241 4.0E-57 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS14965 0f5b0501ce62d971491914ee3fe7cf13 339 SUPERFAMILY SSF69572 3 271 6.41E-82 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS01870 8fcd4f25b8cab5604f256869b4e4467b 258 Gene3D G3DSA:1.20.1260.10 2 258 1.5E-54 T 28-03-2018 IPR012347 Ferritin-related A21D_RS01870 8fcd4f25b8cab5604f256869b4e4467b 258 PIRSF PIRSF037834 1 258 4.7E-83 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A21D_RS01870 8fcd4f25b8cab5604f256869b4e4467b 258 Pfam PF05138 Phenylacetic acid catabolic protein 3 251 1.1E-61 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A21D_RS01870 8fcd4f25b8cab5604f256869b4e4467b 258 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 10 258 2.0E-70 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A21D_RS01870 8fcd4f25b8cab5604f256869b4e4467b 258 SUPERFAMILY SSF47240 3 250 2.68E-54 T 28-03-2018 IPR009078 Ferritin-like superfamily A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 SUPERFAMILY SSF51306 25 179 1.12E-50 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 Gene3D G3DSA:2.10.109.10 24 183 7.6E-46 T 28-03-2018 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 Pfam PF00717 Peptidase S24-like 34 101 2.5E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 176 8.2E-52 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 2.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 2.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 27 43 2.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A21D_RS13280 e2b0ba3fb66d2c840088a963d2d8b8b9 185 ProSitePatterns PS00501 Signal peptidases I serine active site. 36 43 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A21D_RS16590 944bca81e1ca9e52b4472218e6e9374e 258 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 215 4.1E-56 T 28-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 A21D_RS04800 8d74a3f8f6826ec6acdc0ad0857be808 164 Gene3D G3DSA:1.10.10.10 52 121 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 Gene3D G3DSA:3.40.50.720 2 172 7.4E-21 T 28-03-2018 A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 Pfam PF01842 ACT domain 297 337 9.8E-7 T 28-03-2018 IPR002912 ACT domain A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 SUPERFAMILY SSF55021 289 347 2.96E-7 T 28-03-2018 A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 Gene3D G3DSA:3.30.70.260 292 365 1.4E-6 T 28-03-2018 A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 Gene3D G3DSA:1.10.3660.10 182 288 6.0E-23 T 28-03-2018 A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 SUPERFAMILY SSF51735 4 169 3.3E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 SUPERFAMILY SSF48179 174 283 2.27E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A21D_RS16635 b4bf2eeb7a12bc934f37fb5c7c436380 366 Pfam PF02153 Prephenate dehydrogenase 17 274 8.4E-72 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A21D_RS17340 70b043c636cb286bb4218191f208e340 198 Gene3D G3DSA:1.20.120.330 31 118 4.9E-8 T 28-03-2018 A21D_RS03065 f98bd519f140ff2b63ec09a79b82729b 241 Gene3D G3DSA:1.10.4030.10 57 177 6.6E-20 T 28-03-2018 A21D_RS03065 f98bd519f140ff2b63ec09a79b82729b 241 Gene3D G3DSA:1.10.4030.10 178 240 0.041 T 28-03-2018 A21D_RS03065 f98bd519f140ff2b63ec09a79b82729b 241 Pfam PF13624 SurA N-terminal domain 62 173 2.1E-17 T 28-03-2018 A21D_RS03065 f98bd519f140ff2b63ec09a79b82729b 241 SUPERFAMILY SSF109998 63 226 1.14E-23 T 28-03-2018 IPR027304 Trigger factor/SurA domain A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 SMART SM00418 16 94 1.0E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 Pfam PF01022 Bacterial regulatory protein, arsR family 23 68 6.8E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 Gene3D G3DSA:1.10.10.10 3 100 6.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 SUPERFAMILY SSF46785 4 97 4.21E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 48 5.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 5.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 5.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS18735 401724dc54b74e451338a00a685b2f8e 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 5.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A21D_RS09525 c54f5d7135babc5a32c94ad7f16b6996 114 Gene3D G3DSA:1.10.260.40 1 113 3.9E-14 T 28-03-2018 A21D_RS09525 c54f5d7135babc5a32c94ad7f16b6996 114 Pfam PF01381 Helix-turn-helix 1 41 2.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A21D_RS09525 c54f5d7135babc5a32c94ad7f16b6996 114 SUPERFAMILY SSF47413 1 48 9.65E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS04100 393e389e6e066780024ef600d3ce2404 255 Pfam PF03609 PTS system sorbose-specific iic component 3 233 3.4E-75 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 A21D_RS05765 48211aa1bb25230f927cff3dc280afb6 355 Pfam PF13343 Bacterial extracellular solute-binding protein 86 341 1.0E-32 T 28-03-2018 A21D_RS05765 48211aa1bb25230f927cff3dc280afb6 355 Gene3D G3DSA:3.40.190.10 185 324 2.3E-6 T 28-03-2018 A21D_RS05765 48211aa1bb25230f927cff3dc280afb6 355 Gene3D G3DSA:3.40.190.10 1 184 2.0E-17 T 28-03-2018 A21D_RS05765 48211aa1bb25230f927cff3dc280afb6 355 SUPERFAMILY SSF53850 34 349 4.55E-44 T 28-03-2018 A21D_RS13010 8fbd2088d260495ccf1679904a88caf2 299 Gene3D G3DSA:1.10.10.60 222 271 2.7E-9 T 28-03-2018 A21D_RS13010 8fbd2088d260495ccf1679904a88caf2 299 Pfam PF13556 PucR C-terminal helix-turn-helix domain 236 293 6.7E-19 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A21D_RS13010 8fbd2088d260495ccf1679904a88caf2 299 SUPERFAMILY SSF46689 237 270 3.05E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS11935 4582d1538eb69b5f34067ca4fb983bcf 257 SUPERFAMILY SSF53474 7 244 7.54E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS11935 4582d1538eb69b5f34067ca4fb983bcf 257 Pfam PF00975 Thioesterase domain 19 235 2.4E-21 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A21D_RS11935 4582d1538eb69b5f34067ca4fb983bcf 257 Gene3D G3DSA:3.40.50.1820 2 246 1.5E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS08350 88976bc53620c1cdbcd73d2beaa3d9f9 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 4.6E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A21D_RS14895 6097f2c79f3eb529478e475c4ee68453 132 SUPERFAMILY SSF46785 9 84 2.47E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14895 6097f2c79f3eb529478e475c4ee68453 132 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS14895 6097f2c79f3eb529478e475c4ee68453 132 Gene3D G3DSA:1.10.10.10 5 78 4.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS14895 6097f2c79f3eb529478e475c4ee68453 132 SMART SM00345 17 76 3.8E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A21D_RS19460 912352431278aeefd89bd1aba268ba18 182 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 180 3.1E-32 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS19460 912352431278aeefd89bd1aba268ba18 182 SMART SM01207 8 179 8.0E-32 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS19460 912352431278aeefd89bd1aba268ba18 182 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 176 12.385 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 PRINTS PR00095 Anthranilate synthase component I signature 317 330 4.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 PRINTS PR00095 Anthranilate synthase component I signature 397 411 4.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 PRINTS PR00095 Anthranilate synthase component I signature 412 426 4.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 PRINTS PR00095 Anthranilate synthase component I signature 303 316 4.6E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 Pfam PF00425 chorismate binding enzyme 202 455 8.1E-98 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 SUPERFAMILY SSF56322 11 461 1.96E-147 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 Gene3D G3DSA:3.60.120.10 6 464 2.9E-156 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 Pfam PF04715 Anthranilate synthase component I, N terminal region 18 156 4.1E-33 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS03220 655886a7b48f0848326fb8bcc5a5b41f 469 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 17 462 3.0E-175 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A21D_RS08380 70a0dbb9b22e502538d53924d16e3faa 201 Gene3D G3DSA:3.40.30.10 61 200 4.1E-38 T 28-03-2018 A21D_RS08380 70a0dbb9b22e502538d53924d16e3faa 201 Pfam PF00578 AhpC/TSA family 66 183 4.2E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS08380 70a0dbb9b22e502538d53924d16e3faa 201 ProSitePatterns PS00194 Thioredoxin family active site. 94 112 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A21D_RS08380 70a0dbb9b22e502538d53924d16e3faa 201 SUPERFAMILY SSF52833 63 199 1.75E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS01405 ca47943609f89b76c1c60205145b8b79 152 Gene3D G3DSA:3.30.530.20 5 145 2.3E-10 T 28-03-2018 IPR023393 START-like domain A21D_RS01405 ca47943609f89b76c1c60205145b8b79 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 131 4.6E-6 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase A21D_RS01405 ca47943609f89b76c1c60205145b8b79 152 SUPERFAMILY SSF55961 7 141 2.99E-17 T 28-03-2018 A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 Gene3D G3DSA:3.90.1150.10 263 381 8.9E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 Pfam PF00266 Aminotransferase class-V 4 365 1.4E-85 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 SUPERFAMILY SSF53383 3 377 4.92E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 Gene3D G3DSA:3.40.640.10 12 256 4.4E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS15385 169d36abfe51587d4c3d6a7874152db9 381 PIRSF PIRSF005572 1 380 7.6E-126 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 SUPERFAMILY SSF51735 4 259 7.66E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 Pfam PF00106 short chain dehydrogenase 9 199 5.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS16275 973596d5f8f25a05978dd3709ba66e52 266 Gene3D G3DSA:3.40.50.720 1 266 1.3E-45 T 28-03-2018 A21D_RS13675 a04a743f0746869416fe7ca703ab2fb7 316 Gene3D G3DSA:1.10.10.10 102 295 0.11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13675 a04a743f0746869416fe7ca703ab2fb7 316 ProDom PD030925 PLASMID TRANSCRIPTION REP DNA-BINDING REGULATION 14-3 REPLICATION ORF REP14-2 CMK25 101 203 4.0E-6 T 28-03-2018 A21D_RS17560 02fb69efff7c120c17047185fab28baa 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 2.0E-39 T 28-03-2018 IPR007347 Sporulation stage V, protein S A21D_RS17560 02fb69efff7c120c17047185fab28baa 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 8.3E-40 T 28-03-2018 IPR007347 Sporulation stage V, protein S A21D_RS03280 2e8c6b8b32b87e85a9f0bcfbce3fcd4c 229 SUPERFAMILY SSF52540 1 213 3.36E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS03280 2e8c6b8b32b87e85a9f0bcfbce3fcd4c 229 Pfam PF00005 ABC transporter 17 152 6.8E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS03280 2e8c6b8b32b87e85a9f0bcfbce3fcd4c 229 SMART SM00382 26 201 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS03280 2e8c6b8b32b87e85a9f0bcfbce3fcd4c 229 Gene3D G3DSA:3.40.50.300 1 228 8.7E-48 T 28-03-2018 A21D_RS16360 acb6abc9b2ca4f91ff95f561f37ea520 142 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 11 141 1.0E-38 T 28-03-2018 IPR020144 Stage V sporulation protein AB A21D_RS16360 acb6abc9b2ca4f91ff95f561f37ea520 142 Pfam PF13782 Stage V sporulation protein AB 29 137 4.6E-32 T 28-03-2018 IPR020144 Stage V sporulation protein AB A21D_RS00225 826e8c43e3a5e8b14491c3a388c30a78 144 Pfam PF01592 NifU-like N terminal domain 10 129 7.6E-34 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A21D_RS00225 826e8c43e3a5e8b14491c3a388c30a78 144 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 141 1.6E-56 T 28-03-2018 A21D_RS00225 826e8c43e3a5e8b14491c3a388c30a78 144 Gene3D G3DSA:3.90.1010.10 3 142 9.7E-52 T 28-03-2018 A21D_RS00225 826e8c43e3a5e8b14491c3a388c30a78 144 SUPERFAMILY SSF82649 2 143 2.79E-49 T 28-03-2018 A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 SUPERFAMILY SSF117916 1 74 1.47E-6 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 Gene3D G3DSA:3.30.300.130 1 94 4.6E-11 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 Gene3D G3DSA:3.40.50.300 95 322 8.4E-51 T 28-03-2018 A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 SUPERFAMILY SSF52540 109 350 2.8E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 ProSitePatterns PS01215 Mrp family signature. 212 228 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 346 3.1E-86 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 Pfam PF01883 Iron-sulfur cluster assembly protein 4 59 1.1E-5 T 28-03-2018 IPR002744 MIP18 family-like A21D_RS05655 b988d1c23f3088c1f82c40e5bc8acf3e 352 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 347 33.544 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein A21D_RS16395 b5af85c9a4ef5062480d914b794d3900 244 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 243 25.052 T 28-03-2018 IPR003768 Segregation and condensation protein A A21D_RS16395 b5af85c9a4ef5062480d914b794d3900 244 Pfam PF02616 Segregation and condensation protein ScpA 21 239 5.4E-50 T 28-03-2018 IPR003768 Segregation and condensation protein A A21D_RS16395 b5af85c9a4ef5062480d914b794d3900 244 Gene3D G3DSA:1.10.10.580 171 242 3.7E-12 T 28-03-2018 A21D_RS10380 582db69b715e30247fd15196a65e73e5 511 PIRSF PIRSF019260 6 511 3.7E-149 T 28-03-2018 IPR016753 Phage portal protein PBSX family, Firmicutes A21D_RS10380 582db69b715e30247fd15196a65e73e5 511 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 35 404 7.7E-106 T 28-03-2018 IPR006430 Phage portal protein PBSX family A21D_RS10380 582db69b715e30247fd15196a65e73e5 511 Pfam PF04860 Phage portal protein 125 448 1.4E-14 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A21D_RS02285 6d5082440b73206fc1272b0e4fb532b6 284 SUPERFAMILY SSF52540 4 227 6.23E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02285 6d5082440b73206fc1272b0e4fb532b6 284 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS02285 6d5082440b73206fc1272b0e4fb532b6 284 SMART SM00382 27 216 2.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS02285 6d5082440b73206fc1272b0e4fb532b6 284 Pfam PF00005 ABC transporter 18 167 4.7E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS02285 6d5082440b73206fc1272b0e4fb532b6 284 Gene3D G3DSA:3.40.50.300 3 239 2.6E-54 T 28-03-2018 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 Gene3D G3DSA:1.20.1090.10 169 355 3.7E-50 T 28-03-2018 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 Pfam PF01761 3-dehydroquinate synthase 65 317 3.6E-90 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 PIRSF PIRSF001455 2 354 2.5E-102 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 344 3.5E-110 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 Gene3D G3DSA:3.40.50.1970 1 168 1.1E-45 T 28-03-2018 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 350 36.815 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A21D_RS16620 e27b0a88c1844c0fee35fa6b3b18f336 357 SUPERFAMILY SSF56796 9 350 9.55E-93 T 28-03-2018 A21D_RS06310 8a7e6b0d4b548cbb0f03ee43a9a45b13 61 Gene3D G3DSA:4.10.830.10 1 61 4.8E-21 T 28-03-2018 A21D_RS06310 8a7e6b0d4b548cbb0f03ee43a9a45b13 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06310 8a7e6b0d4b548cbb0f03ee43a9a45b13 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.939 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z A21D_RS06310 8a7e6b0d4b548cbb0f03ee43a9a45b13 61 SUPERFAMILY SSF57716 3 61 7.13E-22 T 28-03-2018 A21D_RS06310 8a7e6b0d4b548cbb0f03ee43a9a45b13 61 Pfam PF00253 Ribosomal protein S14p/S29e 11 60 8.8E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS10465 48a2db2c2856cb928272bf75e2820e92 126 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 125 1.0E-17 T 28-03-2018 IPR022555 Protein of unknown function, DUF2577 A21D_RS10465 48a2db2c2856cb928272bf75e2820e92 126 Pfam PF10844 Protein of unknown function (DUF2577) 7 125 1.6E-20 T 28-03-2018 IPR022555 Protein of unknown function, DUF2577 A21D_RS00690 6fe12ec77234b836d1ba3cbf2e0f127e 173 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 4.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS00690 6fe12ec77234b836d1ba3cbf2e0f127e 173 Gene3D G3DSA:2.160.10.10 55 171 3.8E-27 T 28-03-2018 A21D_RS00690 6fe12ec77234b836d1ba3cbf2e0f127e 173 SUPERFAMILY SSF51161 11 161 4.99E-32 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 437 4.6E-154 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 347 369 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 211 230 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 407 427 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 92 114 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 183 201 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 PRINTS PR00175 Sodium/alanine symporter signature 302 320 7.2E-53 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS10570 d4e3d8e7d75af1147b760e6bc16dc6f2 451 Pfam PF01235 Sodium:alanine symporter family 54 447 3.5E-150 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A21D_RS02440 2e8b14bec299a91905a7ab37ce04b107 434 SUPERFAMILY SSF51905 5 270 7.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02440 2e8b14bec299a91905a7ab37ce04b107 434 Gene3D G3DSA:3.50.50.60 2 233 4.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A21D_RS02440 2e8b14bec299a91905a7ab37ce04b107 434 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 348 2.8E-84 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A21D_RS08200 502ec34e291aba78e17ea97d5327ceb8 502 PIRSF PIRSF002457 8 502 3.0E-127 T 28-03-2018 IPR030676 Citrate carrier CitT-related A21D_RS08200 502ec34e291aba78e17ea97d5327ceb8 502 Pfam PF00939 Sodium:sulfate symporter transmembrane region 22 502 1.4E-104 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A21D_RS08200 502ec34e291aba78e17ea97d5327ceb8 502 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 42 496 1.1E-68 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A21D_RS15935 5364bef67e858753f5f847c0f5909001 56 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 22 51 7.0E-7 T 28-03-2018 IPR024490 Protein of unknown function DUF2759 A21D_RS15935 5364bef67e858753f5f847c0f5909001 56 Pfam PF10958 Protein of unknown function (DUF2759) 8 52 2.4E-17 T 28-03-2018 IPR024490 Protein of unknown function DUF2759 A21D_RS01930 be018a47743b2ccb31ea66d5c3b13127 155 SUPERFAMILY SSF55729 2 140 2.47E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS01930 be018a47743b2ccb31ea66d5c3b13127 155 Gene3D G3DSA:3.40.630.30 1 145 4.6E-17 T 28-03-2018 A21D_RS01930 be018a47743b2ccb31ea66d5c3b13127 155 Pfam PF13302 Acetyltransferase (GNAT) domain 33 134 1.8E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 SUPERFAMILY SSF142433 255 414 1.07E-49 T 28-03-2018 IPR008136 CinA, C-terminal A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 415 147.766 T 28-03-2018 IPR008135 Competence-induced protein CinA A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 SMART SM00852 8 174 1.2E-30 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 5 414 4.2E-123 T 28-03-2018 IPR008135 Competence-induced protein CinA A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 Pfam PF02464 Competence-damaged protein 261 413 2.5E-52 T 28-03-2018 IPR008136 CinA, C-terminal A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 SUPERFAMILY SSF53218 5 210 8.64E-38 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 PIRSF PIRSF006728 4 415 1.7E-150 T 28-03-2018 IPR008135 Competence-induced protein CinA A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 Gene3D G3DSA:3.40.980.10 2 175 4.3E-40 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 Pfam PF00994 Probable molybdopterin binding domain 8 173 2.3E-34 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 168 2.0E-30 T 28-03-2018 IPR001453 MoaB/Mog domain A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 Gene3D G3DSA:3.90.950.20 251 415 2.8E-54 T 28-03-2018 A21D_RS17580 07ac273ad414d0b1ebf1f249be60afe1 415 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 270 411 5.3E-39 T 28-03-2018 IPR008136 CinA, C-terminal A21D_RS12040 fdbc6e7de6deaddef40136df007129e7 153 Pfam PF12867 DinB superfamily 8 142 3.7E-15 T 28-03-2018 IPR024775 DinB-like domain A21D_RS12040 fdbc6e7de6deaddef40136df007129e7 153 SUPERFAMILY SSF109854 3 145 3.3E-18 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A21D_RS12040 fdbc6e7de6deaddef40136df007129e7 153 Gene3D G3DSA:1.20.120.450 1 146 3.3E-18 T 28-03-2018 A21D_RS03405 96f9cf71ef81978df8e4787b8e96ed8e 101 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 98 6.0E-4 T 28-03-2018 A21D_RS02965 f4b8fc7af37cf91c4361e9dff2a68230 51 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 2 48 1.2E-11 T 28-03-2018 IPR022248 TNF receptor family, RELT A21D_RS01865 9817d5fe94269f7e6a672cc9395882d7 179 Pfam PF01883 Iron-sulfur cluster assembly protein 8 73 2.6E-14 T 28-03-2018 IPR002744 MIP18 family-like A21D_RS01865 9817d5fe94269f7e6a672cc9395882d7 179 Gene3D G3DSA:3.30.300.130 5 108 1.8E-21 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS01865 9817d5fe94269f7e6a672cc9395882d7 179 SUPERFAMILY SSF117916 6 107 1.53E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A21D_RS01865 9817d5fe94269f7e6a672cc9395882d7 179 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 166 4.7E-53 T 28-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit A21D_RS13475 4c5fe8a6da42682d91d81077c57e1ccb 227 PIRSF PIRSF029008 1 225 1.7E-75 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS13475 4c5fe8a6da42682d91d81077c57e1ccb 227 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 26.388 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS13475 4c5fe8a6da42682d91d81077c57e1ccb 227 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 217 4.7E-49 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 Gene3D G3DSA:2.40.260.10 30 247 4.6E-51 T 28-03-2018 IPR023365 Sortase domain A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 Gene3D G3DSA:1.20.5.100 250 275 6.0E-4 T 28-03-2018 A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 TIGRFAM TIGR01076 sortase_fam: sortase 102 235 6.3E-50 T 28-03-2018 IPR005754 Sortase family A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 244 273 5.7E-4 T 28-03-2018 A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 Pfam PF04203 Sortase family 104 229 6.9E-27 T 28-03-2018 IPR005754 Sortase family A21D_RS01750 9f3f02c8592fd4026333e279811eb685 279 SUPERFAMILY SSF63817 92 232 5.89E-44 T 28-03-2018 IPR023365 Sortase domain A21D_RS04120 5149000f61ec5cdcee09e55116d40414 205 Pfam PF08241 Methyltransferase domain 44 137 3.5E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS04120 5149000f61ec5cdcee09e55116d40414 205 Gene3D G3DSA:3.40.50.150 3 195 7.5E-28 T 28-03-2018 A21D_RS04120 5149000f61ec5cdcee09e55116d40414 205 SUPERFAMILY SSF53335 10 189 2.28E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS16975 51a240a1bec169569f5a48fa80818ac4 151 Pfam PF06713 Bacterial PH domain 62 136 8.1E-17 T 28-03-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 A21D_RS08170 fb4b5c3c62c7934bf74fa98e3ae628d3 576 SUPERFAMILY SSF51182 488 568 1.22E-66 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS08170 fb4b5c3c62c7934bf74fa98e3ae628d3 576 SUPERFAMILY SSF51182 225 461 1.22E-66 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS08170 fb4b5c3c62c7934bf74fa98e3ae628d3 576 Gene3D G3DSA:2.60.120.10 484 576 4.8E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS08170 fb4b5c3c62c7934bf74fa98e3ae628d3 576 Gene3D G3DSA:2.60.120.10 224 391 8.2E-29 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS08170 fb4b5c3c62c7934bf74fa98e3ae628d3 576 Gene3D G3DSA:2.60.120.10 392 463 2.8E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS13055 c75b183c9816e27df4873b5d142334ad 986 SUPERFAMILY SSF52540 875 977 3.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13055 c75b183c9816e27df4873b5d142334ad 986 SUPERFAMILY SSF52540 189 220 3.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13055 c75b183c9816e27df4873b5d142334ad 986 SUPERFAMILY SSF52540 3 148 3.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS13055 c75b183c9816e27df4873b5d142334ad 986 Gene3D G3DSA:3.40.50.300 15 978 7.7E-16 T 28-03-2018 A21D_RS13055 c75b183c9816e27df4873b5d142334ad 986 Pfam PF13514 AAA domain 3 197 9.9E-19 T 28-03-2018 A21D_RS13390 d494edc97871e4250ad5c7d5c5511215 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 8 275 16.641 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A21D_RS13390 d494edc97871e4250ad5c7d5c5511215 277 Pfam PF02673 Bacitracin resistance protein BacA 14 270 8.2E-72 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 SUPERFAMILY SSF52518 3 192 1.41E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 Pfam PF02780 Transketolase, C-terminal domain 195 314 6.3E-35 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 SMART SM00861 4 179 1.6E-58 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 3.7E-40 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 Gene3D G3DSA:3.40.50.920 195 323 2.1E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 SUPERFAMILY SSF52922 188 322 1.96E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A21D_RS05935 36261c60559c29f502c52f5fa6a546d3 324 Gene3D G3DSA:3.40.50.970 2 194 3.0E-59 T 28-03-2018 A21D_RS13200 29b4e7f785eee38211755a2b413fc8ab 143 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 5 141 22.856 T 28-03-2018 IPR012187 Disulphide bond formation protein BdbC A21D_RS13200 29b4e7f785eee38211755a2b413fc8ab 143 Pfam PF02600 Disulfide bond formation protein DsbB 10 112 1.3E-12 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A21D_RS13200 29b4e7f785eee38211755a2b413fc8ab 143 SUPERFAMILY SSF158442 12 136 4.84E-28 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A21D_RS13200 29b4e7f785eee38211755a2b413fc8ab 143 Gene3D G3DSA:1.20.1550.10 1 122 7.7E-24 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A21D_RS13200 29b4e7f785eee38211755a2b413fc8ab 143 PIRSF PIRSF036659 2 142 1.4E-52 T 28-03-2018 IPR012187 Disulphide bond formation protein BdbC A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 72 87 6.9E-6 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 6.9E-6 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 Gene3D G3DSA:3.40.50.2300 1 200 7.5E-41 T 28-03-2018 A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 124 4.7E-28 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 SUPERFAMILY SSF52788 169 199 3.27E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 SUPERFAMILY SSF52788 1 113 3.27E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS04615 88d864572a7e01312c6c9a1ee3ab4fc8 201 SMART SM00226 1 198 2.3E-26 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A21D_RS09600 4d0b58cf923a38691b2042577d0297e9 285 Gene3D G3DSA:3.20.20.410 1 285 3.7E-83 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A21D_RS09600 4d0b58cf923a38691b2042577d0297e9 285 SUPERFAMILY SSF117396 2 272 1.44E-80 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A21D_RS09600 4d0b58cf923a38691b2042577d0297e9 285 Pfam PF01904 Protein of unknown function DUF72 16 268 7.8E-60 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A21D_RS17105 947ff7651bf254f56ba0013cc4ed9a3a 61 Pfam PF13040 Fur-regulated basic protein B 19 54 3.2E-12 T 28-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS A21D_RS17070 508e606f0394cb9c67393d90ec3b20a0 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 182 4.7E-52 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS17070 508e606f0394cb9c67393d90ec3b20a0 193 SMART SM01207 8 183 2.2E-80 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS17070 508e606f0394cb9c67393d90ec3b20a0 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 191 19.945 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS17070 508e606f0394cb9c67393d90ec3b20a0 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 192 9.2E-63 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A21D_RS01675 5cd678f237e7be76b39e6704c4624878 228 Gene3D G3DSA:1.10.150.130 1 132 1.4E-7 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A21D_RS03630 6dac670a31ae267b3c289d403345b4eb 527 Pfam PF02652 L-lactate permease 3 522 5.1E-103 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A21D_RS12785 fbece2bd1766deba35d20f01fe8f7fb1 319 Pfam PF00326 Prolyl oligopeptidase family 120 315 2.0E-11 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A21D_RS12785 fbece2bd1766deba35d20f01fe8f7fb1 319 SUPERFAMILY SSF53474 70 316 4.73E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS12785 fbece2bd1766deba35d20f01fe8f7fb1 319 Gene3D G3DSA:3.40.50.1820 59 317 9.9E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS02245 b4052cef127955c6d64c4d0095df8560 92 Pfam PF00144 Beta-lactamase 2 82 1.9E-9 T 28-03-2018 IPR001466 Beta-lactamase-related A21D_RS02245 b4052cef127955c6d64c4d0095df8560 92 Gene3D G3DSA:3.40.710.10 1 85 4.4E-13 T 28-03-2018 A21D_RS02245 b4052cef127955c6d64c4d0095df8560 92 SUPERFAMILY SSF56601 2 82 1.55E-12 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS19590 65fbead740548dc5cde1967d8919064e 378 Pfam PF14082 Domain of unknown function (DUF4263) 200 359 5.3E-29 T 28-03-2018 IPR025359 Protein of unknown function DUF4263 A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 Gene3D G3DSA:3.40.50.720 1 42 2.2E-7 T 28-03-2018 A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 Gene3D G3DSA:3.40.50.720 43 261 6.6E-68 T 28-03-2018 A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 2.5E-67 T 28-03-2018 A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A21D_RS09550 a53ccf5df0146d590a56f7b096118456 263 SUPERFAMILY SSF51735 5 255 8.72E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS09710 39dca42d240e394e7e441b5586220813 155 Pfam PF08905 Domain of unknown function (DUF1850) 50 136 6.4E-22 T 28-03-2018 IPR015001 Protein of unknown function DUF1850 A21D_RS16665 bcf930d06221a7fdb9dc5fdbcca4e0ef 224 SUPERFAMILY SSF81342 6 224 1.27E-61 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A21D_RS16665 bcf930d06221a7fdb9dc5fdbcca4e0ef 224 PIRSF PIRSF000032 2 224 1.1E-101 T 28-03-2018 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 A21D_RS16665 bcf930d06221a7fdb9dc5fdbcca4e0ef 224 Gene3D G3DSA:1.20.810.10 2 224 1.2E-76 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A21D_RS16665 bcf930d06221a7fdb9dc5fdbcca4e0ef 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 5.0E-48 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A21D_RS04585 41a365ddae1d660771bc9e48eb4ef642 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 9.1E-90 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A21D_RS04585 41a365ddae1d660771bc9e48eb4ef642 209 SUPERFAMILY SSF53271 4 207 4.2E-71 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS04585 41a365ddae1d660771bc9e48eb4ef642 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 46.991 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A21D_RS04585 41a365ddae1d660771bc9e48eb4ef642 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 1.3E-75 T 28-03-2018 A21D_RS04585 41a365ddae1d660771bc9e48eb4ef642 209 Gene3D G3DSA:3.40.50.2020 2 207 3.8E-65 T 28-03-2018 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 SUPERFAMILY SSF161111 7 208 6.8E-56 T 28-03-2018 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 SUPERFAMILY SSF160240 210 287 4.84E-20 T 28-03-2018 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 288 2.7E-71 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 Pfam PF01545 Cation efflux family 15 206 1.8E-50 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 Gene3D G3DSA:1.20.1510.10 11 206 6.6E-44 T 28-03-2018 A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 Pfam PF16916 Dimerisation domain of Zinc Transporter 211 287 2.8E-18 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A21D_RS12960 cc7e6c8b4a3e996ab6d9a035b57d5826 290 Gene3D G3DSA:3.30.70.1350 208 290 4.2E-17 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A21D_RS08560 e0950b3b02f528f1d4a5ade00df334dc 151 SUPERFAMILY SSF55804 2 144 8.76E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS08560 e0950b3b02f528f1d4a5ade00df334dc 151 Gene3D G3DSA:3.40.930.10 1 146 7.6E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS08560 e0950b3b02f528f1d4a5ade00df334dc 151 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 128 1.9E-36 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A21D_RS08560 e0950b3b02f528f1d4a5ade00df334dc 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 144 9.7E-34 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS00275 72ec0d1795fa06dadacec28c78d0c9e9 117 Pfam PF03960 ArsC family 8 114 6.2E-17 T 28-03-2018 IPR006660 Arsenate reductase-like A21D_RS00275 72ec0d1795fa06dadacec28c78d0c9e9 117 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 116 2.1E-36 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR A21D_RS00275 72ec0d1795fa06dadacec28c78d0c9e9 117 Gene3D G3DSA:3.40.30.10 1 116 3.5E-36 T 28-03-2018 A21D_RS00275 72ec0d1795fa06dadacec28c78d0c9e9 117 SUPERFAMILY SSF52833 1 116 6.03E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS09255 2010bf71d841e5e4730c66dfc052be8c 336 Gene3D G3DSA:2.60.40.1630 69 211 1.9E-20 T 28-03-2018 A21D_RS09255 2010bf71d841e5e4730c66dfc052be8c 336 Gene3D G3DSA:2.60.40.1640 213 330 9.3E-7 T 28-03-2018 A21D_RS09255 2010bf71d841e5e4730c66dfc052be8c 336 Pfam PF13786 Domain of unknown function (DUF4179) 40 128 1.3E-11 T 28-03-2018 IPR025436 Domain of unknown function DUF4179 A21D_RS18220 883af4ec0a5b9cc9b9a3723d3ad800f2 87 Pfam PF04025 Domain of unknown function (DUF370) 5 76 9.1E-36 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 A21D_RS18220 883af4ec0a5b9cc9b9a3723d3ad800f2 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 77 5.0E-34 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 A21D_RS18220 883af4ec0a5b9cc9b9a3723d3ad800f2 87 Hamap MF_01503 UPF0296 protein . 3 82 28.256 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 801 25.007 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Gene3D G3DSA:1.10.10.10 193 249 4.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Gene3D G3DSA:3.40.50.300 466 702 1.2E-18 T 28-03-2018 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 SMART SM00487 261 460 6.2E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Pfam PF04851 Type III restriction enzyme, res subunit 265 427 2.5E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 SUPERFAMILY SSF52540 530 705 3.94E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Gene3D G3DSA:3.40.50.300 262 429 4.8E-28 T 28-03-2018 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 SUPERFAMILY SSF52540 198 446 2.91E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 TIGRFAM TIGR00595 priA: primosomal protein N' 289 799 1.7E-211 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 Pfam PF00271 Helicase conserved C-terminal domain 557 659 9.6E-8 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS18200 9c5d06c44468c470793cf9cb2e32dea4 802 SMART SM00490 563 660 2.0E-7 T 28-03-2018 IPR001650 Helicase, C-terminal A21D_RS14760 1484191c13b71572c9f24c3473a3b70d 86 SUPERFAMILY SSF102829 10 84 3.01E-18 T 28-03-2018 IPR007838 Cell division protein ZapA-like A21D_RS14760 1484191c13b71572c9f24c3473a3b70d 86 Pfam PF05164 Cell division protein ZapA 10 76 5.4E-15 T 28-03-2018 IPR007838 Cell division protein ZapA-like A21D_RS17500 7f3eac59916ad636b7f8b247e1739f2a 142 Pfam PF13411 MerR HTH family regulatory protein 25 90 2.8E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS17500 7f3eac59916ad636b7f8b247e1739f2a 142 SUPERFAMILY SSF46955 23 103 7.78E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain A21D_RS17500 7f3eac59916ad636b7f8b247e1739f2a 142 Gene3D G3DSA:1.10.1660.10 12 134 1.3E-22 T 28-03-2018 A21D_RS17500 7f3eac59916ad636b7f8b247e1739f2a 142 SMART SM00422 23 91 2.6E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A21D_RS08970 5adbeb275a541c83d97c762740bdeec5 344 Pfam PF03060 Nitronate monooxygenase 7 343 8.6E-86 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A21D_RS08970 5adbeb275a541c83d97c762740bdeec5 344 Gene3D G3DSA:3.20.20.70 2 344 1.8E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS08970 5adbeb275a541c83d97c762740bdeec5 344 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 211 231 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A21D_RS08970 5adbeb275a541c83d97c762740bdeec5 344 SUPERFAMILY SSF51412 109 339 3.36E-55 T 28-03-2018 A21D_RS08970 5adbeb275a541c83d97c762740bdeec5 344 SUPERFAMILY SSF51412 3 74 3.36E-55 T 28-03-2018 A21D_RS00750 f9a098fa625f68e43836155f4e655778 180 ProDom PD102989 YKOP PLASMID 1 176 1.0E-42 T 28-03-2018 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 SMART SM00283 144 419 5.3E-68 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 Gene3D G3DSA:1.10.287.950 74 173 9.0E-4 T 28-03-2018 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 Gene3D G3DSA:1.10.287.950 174 418 9.8E-52 T 28-03-2018 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 SUPERFAMILY SSF58104 130 416 2.62E-62 T 28-03-2018 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 189 372 1.2E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 242 269 2.9E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 271 300 2.9E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS12260 4937f5efb2291d7533e9ccbcf6ca12a6 421 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 168 197 2.9E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 Gene3D G3DSA:3.40.50.300 1 283 4.2E-76 T 28-03-2018 A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 SMART SM00382 27 214 1.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 Pfam PF00005 ABC transporter 18 164 2.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 SUPERFAMILY SSF52540 1 240 1.0E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 SUPERFAMILY SSF54631 298 347 8.78E-5 T 28-03-2018 A21D_RS17065 1b761cecde91f2c0ea27b40b25aa4883 355 Gene3D G3DSA:3.10.580.10 294 351 0.0028 T 28-03-2018 A21D_RS15460 5f6256f1813831bb64984b4bf3a2f3c5 229 Pfam PF07423 Protein of unknown function (DUF1510) 8 222 1.9E-58 T 28-03-2018 IPR009988 Protein of unknown function DUF1510 A21D_RS15460 5f6256f1813831bb64984b4bf3a2f3c5 229 Gene3D G3DSA:1.20.1110.10 17 140 0.0013 T 28-03-2018 A21D_RS03960 308d728e14f0bf35552f5d6ebd209222 236 Gene3D G3DSA:1.20.1250.20 25 211 7.8E-5 T 28-03-2018 A21D_RS02040 dbcc9c2399534226cd8978a4c0889708 418 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 6 407 2.4E-133 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A21D_RS02040 dbcc9c2399534226cd8978a4c0889708 418 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 6 407 2.4E-133 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS02040 dbcc9c2399534226cd8978a4c0889708 418 Pfam PF02378 Phosphotransferase system, EIIC 22 334 4.3E-60 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS02040 dbcc9c2399534226cd8978a4c0889708 418 PIRSF PIRSF006351 1 417 1.4E-144 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 23 292 7.6E-61 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 Pfam PF08443 RimK-like ATP-grasp domain 99 292 7.6E-41 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 Gene3D G3DSA:3.30.1490.20 104 176 6.5E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 SUPERFAMILY SSF56059 90 295 4.6E-43 T 28-03-2018 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 Gene3D G3DSA:3.30.470.20 177 283 7.1E-28 T 28-03-2018 A21D_RS15160 4adc60855cbcc823ad089dfb1b9389c8 302 Gene3D G3DSA:3.40.50.20 6 103 1.6E-14 T 28-03-2018 A21D_RS19295 67be227e713cb6d199c5480cda68ee09 138 SUPERFAMILY SSF49764 25 127 3.14E-18 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS19295 67be227e713cb6d199c5480cda68ee09 138 Gene3D G3DSA:2.60.40.790 14 131 3.4E-20 T 28-03-2018 IPR008978 HSP20-like chaperone A21D_RS19295 67be227e713cb6d199c5480cda68ee09 138 Pfam PF00011 Hsp20/alpha crystallin family 45 127 7.4E-9 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain A21D_RS09365 845783868983d4aaf72ef591013e076f 196 Pfam PF07883 Cupin domain 96 171 1.1E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel A21D_RS09365 845783868983d4aaf72ef591013e076f 196 Gene3D G3DSA:2.60.120.10 71 196 1.7E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS09365 845783868983d4aaf72ef591013e076f 196 SUPERFAMILY SSF51182 54 177 3.37E-26 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS17655 593fc829de4d64158c1f1f27f655f4fc 242 Pfam PF00574 Clp protease 44 217 3.4E-32 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A21D_RS17655 593fc829de4d64158c1f1f27f655f4fc 242 Gene3D G3DSA:3.90.226.10 21 242 5.1E-27 T 28-03-2018 A21D_RS17655 593fc829de4d64158c1f1f27f655f4fc 242 SUPERFAMILY SSF52096 38 225 4.07E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS09020 849fcb227454933c2330c9e39113e100 453 Pfam PF01554 MatE 242 402 3.4E-29 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS09020 849fcb227454933c2330c9e39113e100 453 Pfam PF01554 MatE 17 176 1.9E-33 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS09020 849fcb227454933c2330c9e39113e100 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 416 8.4E-66 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS09020 849fcb227454933c2330c9e39113e100 453 PIRSF PIRSF006603 1 452 3.7E-88 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS14325 2b90fc53d15c3e9b623cb01b833700b1 134 Gene3D G3DSA:1.20.1480.30 23 121 4.2E-8 T 28-03-2018 A21D_RS14325 2b90fc53d15c3e9b623cb01b833700b1 134 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 94 3.0E-27 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 Pfam PF00005 ABC transporter 25 171 5.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 Gene3D G3DSA:3.40.50.300 3 243 1.2E-69 T 28-03-2018 A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 SMART SM00382 34 219 1.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 SUPERFAMILY SSF52540 7 235 4.13E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS06230 7f02e39e0a4ba19b459c12121232dc9d 281 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 8 275 1.0E-117 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 A21D_RS11870 9ae17939858c7aa9045aea37768d92e0 156 SMART SM01321 11 129 4.1E-41 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A21D_RS11870 9ae17939858c7aa9045aea37768d92e0 156 SUPERFAMILY SSF143422 1 129 1.16E-47 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A21D_RS11870 9ae17939858c7aa9045aea37768d92e0 156 Gene3D G3DSA:3.30.70.1290 2 135 1.2E-24 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A21D_RS11870 9ae17939858c7aa9045aea37768d92e0 156 Pfam PF01797 Transposase IS200 like 11 129 2.6E-39 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.961 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 Gene3D G3DSA:2.40.150.20 1 122 7.9E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.2E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 SUPERFAMILY SSF50193 1 122 1.57E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 SMART SM01374 1 122 2.5E-83 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A21D_RS06325 5342c3f89f927733c62bb413d1ebdc7d 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.4E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A21D_RS04705 ecd9785cc359aa32185da4e81260fa86 162 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 160 12.977 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A21D_RS04705 ecd9785cc359aa32185da4e81260fa86 162 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 92 7.5E-31 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A21D_RS04705 ecd9785cc359aa32185da4e81260fa86 162 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 16 81 5.9E-8 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 A21D_RS12775 032196c4eee853bd98e00fb173c2f08d 371 Pfam PF12698 ABC-2 family transporter protein 25 362 5.8E-32 T 28-03-2018 A21D_RS12775 032196c4eee853bd98e00fb173c2f08d 371 Gene3D G3DSA:3.40.1710.10 39 191 7.1E-4 T 28-03-2018 A21D_RS08510 ee70945836ec86eef69b19aa04c92eb5 316 Pfam PF00294 pfkB family carbohydrate kinase 4 299 2.4E-61 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A21D_RS08510 ee70945836ec86eef69b19aa04c92eb5 316 Gene3D G3DSA:3.40.1190.20 2 313 1.0E-72 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08510 ee70945836ec86eef69b19aa04c92eb5 316 SUPERFAMILY SSF53613 3 307 1.17E-87 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS08510 ee70945836ec86eef69b19aa04c92eb5 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A21D_RS05835 5022a18459a540e7221fb34050a6df33 327 Gene3D G3DSA:1.10.3470.10 1 325 1.2E-59 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS05835 5022a18459a540e7221fb34050a6df33 327 Pfam PF01032 FecCD transport family 14 320 1.8E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A21D_RS05835 5022a18459a540e7221fb34050a6df33 327 SUPERFAMILY SSF81345 4 320 1.44E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A21D_RS05120 c00a2f37e84481eb21c8c6f549d0684b 193 Pfam PF14066 Protein of unknown function (DUF4256) 21 193 4.3E-91 T 28-03-2018 IPR025352 Protein of unknown function DUF4256 A21D_RS14275 45dc1a02919b2f4de1edeafbcf100964 104 Pfam PF03413 Peptidase propeptide and YPEB domain 29 99 5.9E-8 T 28-03-2018 IPR025711 PepSY domain A21D_RS11590 2be5c25592804d32142d0f16d13380ad 266 Pfam PF14167 YfkD-like protein 39 264 2.7E-108 T 28-03-2018 IPR025548 YfkD-like protein A21D_RS11555 58566b9529d9e7bf3e0522906f28d358 274 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 7 268 2.7E-61 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS11555 58566b9529d9e7bf3e0522906f28d358 274 PIRSF PIRSF035875 2 274 3.1E-78 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS11555 58566b9529d9e7bf3e0522906f28d358 274 Pfam PF03631 Virulence factor BrkB 20 269 3.5E-68 T 28-03-2018 IPR017039 Virulence factor BrkB A21D_RS06465 58caf498e78d6aa2ca2f364870f51290 169 Gene3D G3DSA:3.40.50.1010 56 106 0.24 T 28-03-2018 IPR029060 PIN domain-like A21D_RS06465 58caf498e78d6aa2ca2f364870f51290 169 Pfam PF05991 YacP-like NYN domain 4 166 1.6E-55 T 28-03-2018 IPR010298 Protein of unknown function DUF901 A21D_RS14110 2ed191d6313b6950b87905fcf9e3056a 449 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 417 2.3E-45 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS14110 2ed191d6313b6950b87905fcf9e3056a 449 PIRSF PIRSF006603 1 447 1.2E-72 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS14110 2ed191d6313b6950b87905fcf9e3056a 449 Pfam PF01554 MatE 23 184 2.2E-29 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS14110 2ed191d6313b6950b87905fcf9e3056a 449 Pfam PF01554 MatE 251 399 7.2E-18 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS11135 092415c7fbad903921a24427efc6a1b6 100 PIRSF PIRSF012508 1 100 6.0E-39 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD A21D_RS11135 092415c7fbad903921a24427efc6a1b6 100 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 4.8E-39 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD A21D_RS11135 092415c7fbad903921a24427efc6a1b6 100 Pfam PF01371 Trp repressor protein 10 94 1.6E-27 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 A21D_RS11135 092415c7fbad903921a24427efc6a1b6 100 Gene3D G3DSA:1.10.1270.10 1 100 4.3E-22 T 28-03-2018 A21D_RS11135 092415c7fbad903921a24427efc6a1b6 100 SUPERFAMILY SSF48295 3 95 4.08E-28 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A21D_RS16230 301d07732661d8874f44392df14629d8 109 Gene3D G3DSA:3.90.226.10 1 83 2.0E-5 T 28-03-2018 A21D_RS16230 301d07732661d8874f44392df14629d8 109 Pfam PF01039 Carboxyl transferase domain 3 63 1.7E-11 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A21D_RS16230 301d07732661d8874f44392df14629d8 109 SUPERFAMILY SSF52096 2 86 1.28E-8 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS12750 682802e0759a9da2c4cfb9ac498a7a65 372 Pfam PF07730 Histidine kinase 172 230 3.6E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A21D_RS12750 682802e0759a9da2c4cfb9ac498a7a65 372 Gene3D G3DSA:3.30.565.10 228 366 7.3E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS04225 7e44569a32ad9419fae9b88610436ca6 361 Pfam PF00953 Glycosyl transferase family 4 77 230 4.1E-41 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A21D_RS04225 7e44569a32ad9419fae9b88610436ca6 361 ProSitePatterns PS01348 MraY family signature 2. 150 161 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A21D_RS04555 db89a6479614b3e9f3de92a1968e381e 175 SUPERFAMILY SSF81573 78 136 3.53E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A21D_RS04555 db89a6479614b3e9f3de92a1968e381e 175 Pfam PF00430 ATP synthase B/B' CF(0) 24 152 1.2E-35 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A21D_RS04555 db89a6479614b3e9f3de92a1968e381e 175 Gene3D G3DSA:1.20.5.620 70 137 4.1E-7 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A21D_RS04555 db89a6479614b3e9f3de92a1968e381e 175 Hamap MF_01398 ATP synthase subunit b [atpF]. 11 153 13.454 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A21D_RS04555 db89a6479614b3e9f3de92a1968e381e 175 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 25 171 1.1E-42 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A21D_RS00765 8b2374a28c1320c39a24071ad0232246 469 SUPERFAMILY SSF51261 265 468 8.89E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS00765 8b2374a28c1320c39a24071ad0232246 469 SUPERFAMILY SSF57997 27 137 1.37E-5 T 28-03-2018 A21D_RS00765 8b2374a28c1320c39a24071ad0232246 469 Pfam PF01551 Peptidase family M23 356 455 2.6E-30 T 28-03-2018 IPR016047 Peptidase M23 A21D_RS00765 8b2374a28c1320c39a24071ad0232246 469 Gene3D G3DSA:2.70.70.10 175 469 3.9E-40 T 28-03-2018 A21D_RS00765 8b2374a28c1320c39a24071ad0232246 469 Gene3D G3DSA:1.20.5.50 19 137 9.9E-8 T 28-03-2018 A21D_RS02725 0b8ab635ec056bb9cd8d01de95ac7543 364 SUPERFAMILY SSF53383 3 359 2.67E-38 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS02725 0b8ab635ec056bb9cd8d01de95ac7543 364 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 2 359 2.9E-131 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 A21D_RS02725 0b8ab635ec056bb9cd8d01de95ac7543 364 Gene3D G3DSA:3.40.190.10 269 345 0.14 T 28-03-2018 A21D_RS02725 0b8ab635ec056bb9cd8d01de95ac7543 364 Gene3D G3DSA:3.40.640.10 16 268 3.5E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS02725 0b8ab635ec056bb9cd8d01de95ac7543 364 Pfam PF01212 Beta-eliminating lyase 23 284 1.7E-9 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A21D_RS12240 270bbe66db0634b9df4b43ab6897be91 345 SUPERFAMILY SSF51004 12 345 1.96E-47 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A21D_RS12240 270bbe66db0634b9df4b43ab6897be91 345 Pfam PF10282 Lactonase, 7-bladed beta-propeller 8 343 4.6E-120 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller A21D_RS12240 270bbe66db0634b9df4b43ab6897be91 345 Gene3D G3DSA:2.130.10.10 2 345 2.3E-49 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A21D_RS00250 d57c2ed3e2c075c1d55130461162043b 222 Gene3D G3DSA:1.10.3720.10 10 222 5.0E-41 T 28-03-2018 A21D_RS00250 d57c2ed3e2c075c1d55130461162043b 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 222 2.3E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS00250 d57c2ed3e2c075c1d55130461162043b 222 SUPERFAMILY SSF161098 14 210 1.83E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07010 e93219a0b0b941472d564b25a418bb2e 178 Gene3D G3DSA:1.10.3210.10 6 176 3.9E-17 T 28-03-2018 A21D_RS07010 e93219a0b0b941472d564b25a418bb2e 178 Pfam PF01966 HD domain 24 135 5.9E-14 T 28-03-2018 IPR006674 HD domain A21D_RS07010 e93219a0b0b941472d564b25a418bb2e 178 SUPERFAMILY SSF109604 13 137 7.33E-21 T 28-03-2018 A21D_RS07010 e93219a0b0b941472d564b25a418bb2e 178 TIGRFAM TIGR00277 HDIG: HDIG domain 22 105 4.7E-9 T 28-03-2018 IPR006675 HDIG domain A21D_RS07010 e93219a0b0b941472d564b25a418bb2e 178 SMART SM00471 19 148 2.9E-5 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS11125 cde189d95694b786fdc299f9237d3816 272 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 4.8E-79 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A21D_RS11125 cde189d95694b786fdc299f9237d3816 272 Gene3D G3DSA:3.40.1190.20 1 270 2.4E-52 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS11125 cde189d95694b786fdc299f9237d3816 272 SUPERFAMILY SSF53613 1 263 2.38E-71 T 28-03-2018 IPR029056 Ribokinase-like A21D_RS11125 cde189d95694b786fdc299f9237d3816 272 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 7.8E-83 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A21D_RS00825 b2bd67804bd997ddd6b5f279f90ef5dd 485 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 8 103 2.8E-29 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 A21D_RS00825 b2bd67804bd997ddd6b5f279f90ef5dd 485 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 211 472 4.8E-53 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 A21D_RS00825 b2bd67804bd997ddd6b5f279f90ef5dd 485 Gene3D G3DSA:3.90.20.10 337 483 4.5E-6 T 28-03-2018 A21D_RS08005 486cc5fe380229f1de8fdf31970119b0 180 Gene3D G3DSA:1.10.10.10 1 163 5.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08005 486cc5fe380229f1de8fdf31970119b0 180 SUPERFAMILY SSF46785 8 159 2.41E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS08005 486cc5fe380229f1de8fdf31970119b0 180 PIRSF PIRSF006707 1 180 6.8E-38 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 Pfam PF13280 WYL domain 141 312 3.8E-37 T 28-03-2018 IPR026881 WYL domain A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 Pfam PF08279 HTH domain 5 60 9.6E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 PIRSF PIRSF016838 110 321 2.3E-15 T 28-03-2018 IPR028349 Protein PafC A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 PIRSF PIRSF016838 1 51 0.31 T 28-03-2018 IPR028349 Protein PafC A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 Gene3D G3DSA:1.10.10.10 1 63 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS07750 b98628e3306e0b77aa8c611364903407 321 SUPERFAMILY SSF46785 2 59 3.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS15425 daa0473ce8a5142644c5d68dcab8fc95 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 8.0E-38 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 A21D_RS15425 daa0473ce8a5142644c5d68dcab8fc95 89 Hamap MF_01507 UPF0297 protein . 1 85 28.344 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 A21D_RS15425 daa0473ce8a5142644c5d68dcab8fc95 89 PIRSF PIRSF037258 1 88 1.0E-45 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 A21D_RS07835 4b06d5f2084f1c9a999de9053ae27b1f 179 Gene3D G3DSA:2.20.25.10 140 177 3.7E-9 T 28-03-2018 A21D_RS07835 4b06d5f2084f1c9a999de9053ae27b1f 179 Pfam PF04397 LytTr DNA-binding domain 81 176 1.0E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS07835 4b06d5f2084f1c9a999de9053ae27b1f 179 Gene3D G3DSA:2.40.50.40 70 138 6.3E-14 T 28-03-2018 A21D_RS07835 4b06d5f2084f1c9a999de9053ae27b1f 179 SMART SM00850 79 177 4.9E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A21D_RS16215 80d48a421139d853a079b60126f11435 325 Pfam PF06081 Aromatic acid exporter family member 1 2 141 7.5E-48 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 A21D_RS16215 80d48a421139d853a079b60126f11435 325 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 145 308 1.4E-46 T 28-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal A21D_RS11975 967b59fcc1b8bcfb5d1e43ae8e3040df 398 Pfam PF14199 Domain of unknown function (DUF4317) 2 382 2.2E-102 T 28-03-2018 IPR025466 Protein of unknown function DUF4317 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 SUPERFAMILY SSF63520 303 395 7.32E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Gene3D G3DSA:3.40.50.2300 398 491 8.1E-18 T 28-03-2018 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 402 463 2.8E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Gene3D G3DSA:1.10.10.10 82 148 9.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Gene3D G3DSA:1.10.10.10 1 67 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 SUPERFAMILY SSF46785 1 46 4.67E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 SUPERFAMILY SSF52794 399 480 1.36E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Pfam PF08279 HTH domain 6 47 7.6E-9 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Gene3D G3DSA:1.10.1790.10 174 284 1.2E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Pfam PF05043 Mga helix-turn-helix domain 92 156 3.8E-8 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 SUPERFAMILY SSF63520 173 280 3.92E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Gene3D G3DSA:1.10.1790.10 293 397 1.1E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Pfam PF00874 PRD domain 306 392 5.3E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS09495 0da61a8b09dbd2b0b0a016ab3713a4ae 506 Pfam PF00874 PRD domain 188 279 1.6E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 A21D_RS15910 0a4a949ef6c6cfb58e8dead616e57dbf 485 PIRSF PIRSF005690 4 485 3.7E-128 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS15910 0a4a949ef6c6cfb58e8dead616e57dbf 485 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 25 476 6.2E-153 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS02985 13d1e26603ac4161fd9f04ea58ad1856 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 113 1.1E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A21D_RS02985 13d1e26603ac4161fd9f04ea58ad1856 236 SUPERFAMILY SSF161098 15 204 3.18E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02985 13d1e26603ac4161fd9f04ea58ad1856 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 219 2.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02985 13d1e26603ac4161fd9f04ea58ad1856 236 Gene3D G3DSA:1.10.3720.10 1 224 2.6E-39 T 28-03-2018 A21D_RS02985 13d1e26603ac4161fd9f04ea58ad1856 236 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 4 218 4.4E-67 T 28-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD A21D_RS03925 8cea41b31f7818e762a9b9a0ed7258f7 201 Pfam PF07563 Protein of unknown function (DUF1541) 142 193 1.5E-25 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 A21D_RS03925 8cea41b31f7818e762a9b9a0ed7258f7 201 Pfam PF07563 Protein of unknown function (DUF1541) 80 129 4.6E-27 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 A21D_RS03925 8cea41b31f7818e762a9b9a0ed7258f7 201 Gene3D G3DSA:3.40.190.10 1 197 2.1E-4 T 28-03-2018 A21D_RS19115 d75352141e9afd161048257a1a99f2af 272 SUPERFAMILY SSF51695 29 266 6.88E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS19115 d75352141e9afd161048257a1a99f2af 272 Gene3D G3DSA:3.20.20.190 16 272 2.2E-58 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS19115 d75352141e9afd161048257a1a99f2af 272 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 33 259 6.7E-39 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS18140 9d0b75514e66bc091abb2ecb9ed8a2a1 427 Pfam PF00860 Permease family 20 383 5.0E-28 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS10985 8fee5721801fcb9c719363bb1f8d36f4 337 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 210 319 2.0E-23 T 28-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain A21D_RS10985 8fee5721801fcb9c719363bb1f8d36f4 337 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 41 183 1.4E-50 T 28-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal A21D_RS10985 8fee5721801fcb9c719363bb1f8d36f4 337 SUPERFAMILY SSF159774 39 327 1.7E-91 T 28-03-2018 IPR023158 YerB-like A21D_RS10985 8fee5721801fcb9c719363bb1f8d36f4 337 Gene3D G3DSA:3.50.90.10 25 334 5.6E-98 T 28-03-2018 IPR023158 YerB-like A21D_RS17935 e9ced26c9e9ed42369b6967e1f166ef3 250 Pfam PF02108 Flagellar assembly protein FliH 111 237 5.3E-17 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE A21D_RS17935 e9ced26c9e9ed42369b6967e1f166ef3 250 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 12 249 2.2E-58 T 28-03-2018 IPR022524 Flagellar assembly FliH, Bacilli A21D_RS09460 cfe414d747471e3082601150991a48ef 283 PIRSF PIRSF001359 1 283 1.2E-69 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS09460 cfe414d747471e3082601150991a48ef 283 SUPERFAMILY SSF51569 2 280 2.2E-72 T 28-03-2018 A21D_RS09460 cfe414d747471e3082601150991a48ef 283 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 280 2.0E-68 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS09460 cfe414d747471e3082601150991a48ef 283 Pfam PF01116 Fructose-bisphosphate aldolase class-II 3 280 6.4E-81 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS09460 cfe414d747471e3082601150991a48ef 283 Gene3D G3DSA:3.20.20.70 1 283 5.4E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS09900 3fa702090490b54a53ab00feaa7f0398 196 Pfam PF03413 Peptidase propeptide and YPEB domain 130 187 8.7E-13 T 28-03-2018 IPR025711 PepSY domain A21D_RS09900 3fa702090490b54a53ab00feaa7f0398 196 Pfam PF03413 Peptidase propeptide and YPEB domain 48 104 2.5E-9 T 28-03-2018 IPR025711 PepSY domain A21D_RS09900 3fa702090490b54a53ab00feaa7f0398 196 Gene3D G3DSA:3.10.450.40 130 189 6.7E-17 T 28-03-2018 A21D_RS09900 3fa702090490b54a53ab00feaa7f0398 196 Gene3D G3DSA:3.10.450.40 48 106 1.0E-11 T 28-03-2018 A21D_RS01805 ca97dcb8d6be70b3345c9039b5e26d48 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 373 2.1E-58 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS01805 ca97dcb8d6be70b3345c9039b5e26d48 404 Gene3D G3DSA:3.40.50.1100 331 383 0.1 T 28-03-2018 A21D_RS01805 ca97dcb8d6be70b3345c9039b5e26d48 404 Gene3D G3DSA:3.40.50.1100 212 330 1.0E-20 T 28-03-2018 A21D_RS01805 ca97dcb8d6be70b3345c9039b5e26d48 404 Gene3D G3DSA:3.40.50.1100 76 211 5.6E-22 T 28-03-2018 A21D_RS01805 ca97dcb8d6be70b3345c9039b5e26d48 404 SUPERFAMILY SSF53686 3 381 3.8E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A21D_RS14160 558724e777366f7353f8ad10f6709fe7 275 Pfam PF13529 Peptidase_C39 like family 83 247 2.6E-38 T 28-03-2018 A21D_RS14160 558724e777366f7353f8ad10f6709fe7 275 Gene3D G3DSA:3.90.70.10 92 275 4.2E-22 T 28-03-2018 A21D_RS14160 558724e777366f7353f8ad10f6709fe7 275 SUPERFAMILY SSF54001 89 240 2.98E-6 T 28-03-2018 A21D_RS14160 558724e777366f7353f8ad10f6709fe7 275 PIRSF PIRSF032442 15 275 4.1E-72 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 SUPERFAMILY SSF100950 77 235 3.35E-30 T 28-03-2018 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.5E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 SUPERFAMILY SSF46785 4 63 1.24E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 SMART SM01134 76 235 1.3E-56 T 28-03-2018 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 Gene3D G3DSA:3.40.50.1360 68 234 1.7E-33 T 28-03-2018 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 Pfam PF00455 DeoR C terminal sensor domain 78 234 9.3E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 Gene3D G3DSA:1.10.10.10 1 67 8.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS05270 2d27ea92a51c6d1e0492d476514c8b43 252 SMART SM00420 6 58 7.1E-22 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 PRINTS PR00069 Aldo-keto reductase signature 141 158 3.9E-21 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 PRINTS PR00069 Aldo-keto reductase signature 110 128 3.9E-21 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 PRINTS PR00069 Aldo-keto reductase signature 241 265 3.9E-21 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 PRINTS PR00069 Aldo-keto reductase signature 45 69 3.9E-21 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 Pfam PF00248 Aldo/keto reductase family 15 305 1.4E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 141 158 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 SUPERFAMILY SSF51430 1 308 5.5E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS18950 0df06c7fec18e6bfa4ffb85f62089735 310 Gene3D G3DSA:3.20.20.100 1 310 5.8E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 SMART SM00260 6 143 4.0E-37 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 Gene3D G3DSA:2.40.50.180 2 32 0.12 T 28-03-2018 A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 Gene3D G3DSA:2.40.50.180 33 90 1.4E-21 T 28-03-2018 A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 SUPERFAMILY SSF50341 10 148 2.35E-38 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 Pfam PF01584 CheW-like domain 11 146 2.5E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A21D_RS17825 f720ba36ae99506c6935aa1c55e08b81 156 Gene3D G3DSA:2.30.30.40 91 137 7.6E-20 T 28-03-2018 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 Gene3D G3DSA:1.10.357.10 63 185 6.3E-9 T 28-03-2018 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 SUPERFAMILY SSF46689 4 85 4.36E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 Gene3D G3DSA:1.10.10.60 3 62 1.5E-17 T 28-03-2018 A21D_RS03840 d99be1feb88ced9ca237bf678617c7a2 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.4E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A21D_RS04070 c3149c33ba45d480159430fcc7d0f4b4 494 ProSitePatterns PS01303 BCCT family of transporters signature. 309 318 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A21D_RS04070 c3149c33ba45d480159430fcc7d0f4b4 494 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 46 492 5.6E-153 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS04070 c3149c33ba45d480159430fcc7d0f4b4 494 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 492 1.7E-182 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS13480 654ecfa866c995c85c9eccdc656eecf0 396 PIRSF PIRSF007487 1 384 3.4E-74 T 28-03-2018 IPR021176 Competence-induced protein CoiA A21D_RS13480 654ecfa866c995c85c9eccdc656eecf0 396 Pfam PF06054 Competence protein CoiA-like family 1 294 1.5E-64 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like A21D_RS08185 d227a125dfd1e0d909665700452bbdbb 263 Pfam PF03609 PTS system sorbose-specific iic component 6 245 4.5E-63 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 A21D_RS01065 8ba0da79a943fad7552f47924a666117 108 SUPERFAMILY SSF46973 1 98 2.09E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS01065 8ba0da79a943fad7552f47924a666117 108 Gene3D G3DSA:1.20.58.80 1 99 1.9E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS01065 8ba0da79a943fad7552f47924a666117 108 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 97 5.0E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS01065 8ba0da79a943fad7552f47924a666117 108 PIRSF PIRSF000699 1 105 1.5E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS09150 bb56a358b5d4e9d1b4668fe7cf940d73 278 Pfam PF08445 FR47-like protein 205 270 1.8E-10 T 28-03-2018 IPR013653 FR47-like GO:0016747 A21D_RS09150 bb56a358b5d4e9d1b4668fe7cf940d73 278 Gene3D G3DSA:3.40.630.30 142 272 1.2E-12 T 28-03-2018 A21D_RS09150 bb56a358b5d4e9d1b4668fe7cf940d73 278 SUPERFAMILY SSF55729 144 275 3.85E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS04775 29b89049f038f3bd9fd8a73e00381158 540 Gene3D G3DSA:3.40.190.10 48 232 3.7E-30 T 28-03-2018 A21D_RS04775 29b89049f038f3bd9fd8a73e00381158 540 Pfam PF13416 Bacterial extracellular solute-binding protein 74 393 5.7E-13 T 28-03-2018 A21D_RS04775 29b89049f038f3bd9fd8a73e00381158 540 SUPERFAMILY SSF53850 21 537 1.86E-82 T 28-03-2018 A21D_RS04775 29b89049f038f3bd9fd8a73e00381158 540 Gene3D G3DSA:3.40.190.10 306 511 5.7E-11 T 28-03-2018 A21D_RS07120 1bca8616297c4a7f03eb9b18f954971e 212 Pfam PF01712 Deoxynucleoside kinase 7 203 4.6E-50 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain A21D_RS07120 1bca8616297c4a7f03eb9b18f954971e 212 PIRSF PIRSF000705 1 212 3.7E-59 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A21D_RS07120 1bca8616297c4a7f03eb9b18f954971e 212 Gene3D G3DSA:3.40.50.300 1 210 5.2E-41 T 28-03-2018 A21D_RS07120 1bca8616297c4a7f03eb9b18f954971e 212 SUPERFAMILY SSF52540 1 203 4.53E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 SMART SM00342 9 92 2.3E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 Pfam PF12833 Helix-turn-helix domain 16 92 1.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 Gene3D G3DSA:1.10.10.60 51 100 7.4E-11 T 28-03-2018 A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 SUPERFAMILY SSF46689 2 42 5.82E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 SUPERFAMILY SSF46689 45 93 6.72E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A21D_RS05095 e02ca990b17634d95432ac1bf2af92c6 102 Gene3D G3DSA:1.10.10.60 8 50 4.2E-15 T 28-03-2018 A21D_RS03810 df5b74cb3bc7c58b4084bcef28e9fbb9 247 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 235 1.0E-87 T 28-03-2018 A21D_RS03810 df5b74cb3bc7c58b4084bcef28e9fbb9 247 Pfam PF12787 EcsC protein family 7 233 2.6E-73 T 28-03-2018 IPR024787 EcsC protein A21D_RS12975 487381deb31aa69d3d45af4286fea686 202 SUPERFAMILY SSF55729 110 172 8.57E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS12975 487381deb31aa69d3d45af4286fea686 202 SUPERFAMILY SSF55729 10 74 8.57E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS12975 487381deb31aa69d3d45af4286fea686 202 Gene3D G3DSA:3.40.630.30 1 188 5.9E-26 T 28-03-2018 A21D_RS12975 487381deb31aa69d3d45af4286fea686 202 Pfam PF00583 Acetyltransferase (GNAT) family 42 168 1.9E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS18380 62aa8b67b3b723df0eb2869d35fdc19b 260 Pfam PF08478 POTRA domain, FtsQ-type 52 118 1.5E-16 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type A21D_RS18380 62aa8b67b3b723df0eb2869d35fdc19b 260 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 255 26.811 T 28-03-2018 IPR026580 Cell division protein DivIB A21D_RS13935 84dea236ba16ad63c88cf0a6bf1276b8 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 4.3E-31 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A21D_RS13935 84dea236ba16ad63c88cf0a6bf1276b8 118 SUPERFAMILY SSF89360 1 96 1.7E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS13935 84dea236ba16ad63c88cf0a6bf1276b8 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 89 106 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A21D_RS13935 84dea236ba16ad63c88cf0a6bf1276b8 118 Gene3D G3DSA:2.60.300.12 2 111 3.4E-33 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS13935 84dea236ba16ad63c88cf0a6bf1276b8 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.1E-18 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A21D_RS15955 87383772ca703ae0a7b858d5c1ea0f95 148 Pfam PF15980 Putative Competence protein ComGF 60 140 1.6E-13 T 28-03-2018 IPR016977 Competence operon G, ComGF A21D_RS13955 bc0f3c95f860c7260946bbf69ca59698 218 Gene3D G3DSA:2.40.40.10 27 203 1.5E-31 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS13955 bc0f3c95f860c7260946bbf69ca59698 218 SUPERFAMILY SSF50685 127 168 5.23E-6 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A21D_RS13955 bc0f3c95f860c7260946bbf69ca59698 218 Pfam PF06725 3D domain 127 188 6.6E-18 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A21D_RS12330 d4aaa2d25e5053c0afd3511f775f6f11 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 247 5.9E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12330 d4aaa2d25e5053c0afd3511f775f6f11 248 SUPERFAMILY SSF161098 44 231 1.83E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12330 d4aaa2d25e5053c0afd3511f775f6f11 248 Gene3D G3DSA:1.10.3720.10 1 238 5.8E-43 T 28-03-2018 A21D_RS14665 24023db0e0da18d91bb8100be000b5be 76 Pfam PF13276 HTH-like domain 22 56 4.5E-8 T 28-03-2018 IPR025948 HTH-like domain A21D_RS19470 edd2035190092f2ca17b6ed296a2489b 181 SUPERFAMILY SSF103473 71 177 1.18E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS19470 edd2035190092f2ca17b6ed296a2489b 181 Gene3D G3DSA:1.20.1250.20 7 178 0.0011 T 28-03-2018 A21D_RS06045 b1bb5fc794245bb0e8340a39047312cf 198 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 8 194 5.7E-25 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane A21D_RS06045 b1bb5fc794245bb0e8340a39047312cf 198 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 10 194 1.1E-35 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane A21D_RS07045 af2b51fe43d1f79ff7fead5b3a074e78 228 Pfam PF03932 CutC family 1 200 1.4E-53 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A21D_RS07045 af2b51fe43d1f79ff7fead5b3a074e78 228 Gene3D G3DSA:3.20.20.380 1 226 5.2E-69 T 28-03-2018 A21D_RS07045 af2b51fe43d1f79ff7fead5b3a074e78 228 SUPERFAMILY SSF110395 1 226 4.97E-54 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A21D_RS07635 2a6f8975913db00ecec62be5493657f7 133 SUPERFAMILY SSF53927 2 130 1.11E-25 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A21D_RS07635 2a6f8975913db00ecec62be5493657f7 133 Gene3D G3DSA:3.40.140.10 1 131 4.5E-17 T 28-03-2018 A21D_RS00715 958145b15fa80d4a7243dca516aaa9eb 117 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 106 1.9E-29 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 7.0E-47 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 Pfam PF03652 Holliday junction resolvase 1 136 6.3E-43 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 SUPERFAMILY SSF53098 1 136 2.28E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 Gene3D G3DSA:3.30.420.140 1 137 3.6E-43 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 137 24.932 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A21D_RS15430 8cee7e8a1a0fe26a2681889527ddd784 137 SMART SM00732 1 103 7.8E-32 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A21D_RS19650 f071625a1f77167242326d06a6daff46 187 ProDom PD012849 LATE FIBER GP8.5 HEAD 1 131 6.0E-5 T 28-03-2018 A21D_RS14590 27656c9931438d684716e2317f362263 158 Gene3D G3DSA:3.10.129.10 10 142 9.8E-21 T 28-03-2018 A21D_RS14590 27656c9931438d684716e2317f362263 158 SUPERFAMILY SSF54637 14 139 4.54E-21 T 28-03-2018 IPR029069 HotDog domain A21D_RS14590 27656c9931438d684716e2317f362263 158 Pfam PF01575 MaoC like domain 26 118 2.7E-7 T 28-03-2018 IPR002539 MaoC-like domain A21D_RS01950 b0f315a23ebdcbf1d379ed03993ea3a3 151 Gene3D G3DSA:3.40.50.850 1 151 3.8E-35 T 28-03-2018 A21D_RS01950 b0f315a23ebdcbf1d379ed03993ea3a3 151 SUPERFAMILY SSF52499 2 151 3.14E-37 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS01950 b0f315a23ebdcbf1d379ed03993ea3a3 151 Pfam PF00857 Isochorismatase family 3 146 7.3E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A21D_RS05525 d48b4876f8bc1b8360d934f956680a9d 264 Gene3D G3DSA:3.40.50.300 3 264 1.5E-66 T 28-03-2018 A21D_RS05525 d48b4876f8bc1b8360d934f956680a9d 264 SMART SM00382 31 214 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS05525 d48b4876f8bc1b8360d934f956680a9d 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS05525 d48b4876f8bc1b8360d934f956680a9d 264 Pfam PF00005 ABC transporter 22 166 1.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS05525 d48b4876f8bc1b8360d934f956680a9d 264 SUPERFAMILY SSF52540 6 228 1.92E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS07495 4eb7e96a043cc270f373ea7187752446 89 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 86 1.5E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS07495 4eb7e96a043cc270f373ea7187752446 89 Gene3D G3DSA:3.10.180.10 1 89 6.7E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS07495 4eb7e96a043cc270f373ea7187752446 89 SUPERFAMILY SSF54593 3 88 9.02E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS19350 919445b92a23cb8dba8683eef99796ad 435 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 425 2.1E-93 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A21D_RS19350 919445b92a23cb8dba8683eef99796ad 435 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 431 3.4E-94 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A21D_RS19350 919445b92a23cb8dba8683eef99796ad 435 PIRSF PIRSF006066 5 435 6.0E-92 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 1.7E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 Gene3D G3DSA:3.20.20.70 1 286 3.6E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 9.1E-101 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 3.0E-116 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 PIRSF PIRSF001359 1 284 2.1E-111 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS01960 6ac1d4e7d58c3b525c99de8ba1ce94c2 289 SUPERFAMILY SSF51569 1 284 4.25E-92 T 28-03-2018 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 PIRSF PIRSF005962 2 369 3.6E-107 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 Pfam PF07687 Peptidase dimerisation domain 178 267 1.6E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 5 358 1.4E-84 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 SUPERFAMILY SSF53187 3 187 3.02E-65 T 28-03-2018 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 SUPERFAMILY SSF53187 288 368 3.02E-65 T 28-03-2018 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 Gene3D G3DSA:3.40.630.10 2 265 1.8E-49 T 28-03-2018 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 Gene3D G3DSA:3.40.630.10 266 371 7.7E-4 T 28-03-2018 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 SUPERFAMILY SSF55031 176 281 4.19E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 Pfam PF01546 Peptidase family M20/M25/M40 65 363 2.2E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A21D_RS18720 dc1f8d9ac614131a62a5139216c46147 371 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 369 59.1 T 28-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 A21D_RS11260 c75ffe00c81a49ad09d8ce6b7fce26a5 107 SUPERFAMILY SSF52794 7 106 5.76E-27 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS11260 c75ffe00c81a49ad09d8ce6b7fce26a5 107 Gene3D G3DSA:3.40.50.2300 7 107 2.0E-30 T 28-03-2018 A21D_RS11260 c75ffe00c81a49ad09d8ce6b7fce26a5 107 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 8 100 3.3E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS07085 d12fe29519fde5ea70af23454574bc1c 286 Gene3D G3DSA:3.60.15.10 29 264 8.7E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07085 d12fe29519fde5ea70af23454574bc1c 286 SMART SM00849 61 242 2.5E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07085 d12fe29519fde5ea70af23454574bc1c 286 Pfam PF00753 Metallo-beta-lactamase superfamily 65 235 1.1E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS07085 d12fe29519fde5ea70af23454574bc1c 286 SUPERFAMILY SSF56281 54 260 1.68E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS05215 e593a33b07391425c2e710c0d4b0e6a4 130 Pfam PF13276 HTH-like domain 27 84 2.0E-8 T 28-03-2018 IPR025948 HTH-like domain A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 SUPERFAMILY SSF53092 1 136 1.71E-30 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 SUPERFAMILY SSF55920 93 359 1.06E-72 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 Gene3D G3DSA:3.40.350.10 1 136 7.7E-24 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 Pfam PF00557 Metallopeptidase family M24 147 348 9.4E-61 T 28-03-2018 IPR000994 Peptidase M24 A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 1.3E-23 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A21D_RS14470 19f42823cf07df905806bcae0bb81847 365 Gene3D G3DSA:3.90.230.10 137 364 5.9E-72 T 28-03-2018 A21D_RS14950 f139d714d23869a0b3d1292fd6255330 196 Gene3D G3DSA:1.10.3480.10 4 185 2.1E-11 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A21D_RS14950 f139d714d23869a0b3d1292fd6255330 196 SUPERFAMILY SSF89155 53 166 1.22E-11 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A21D_RS14950 f139d714d23869a0b3d1292fd6255330 196 Pfam PF02613 Nitrate reductase delta subunit 50 162 1.0E-5 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A21D_RS16560 ec1499f3b4ece58d4de6c0d69924759a 86 Pfam PF14069 Stage VI sporulation protein F 9 80 1.0E-27 T 28-03-2018 IPR025942 Stage VI sporulation protein F A21D_RS17610 352a14820b1e7140c504fa223550774c 427 Pfam PF05193 Peptidase M16 inactive domain 182 361 7.4E-18 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A21D_RS17610 352a14820b1e7140c504fa223550774c 427 Gene3D G3DSA:3.30.830.10 224 427 1.4E-20 T 28-03-2018 A21D_RS17610 352a14820b1e7140c504fa223550774c 427 Pfam PF00675 Insulinase (Peptidase family M16) 63 174 3.4E-17 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A21D_RS17610 352a14820b1e7140c504fa223550774c 427 SUPERFAMILY SSF63411 14 219 8.21E-42 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17610 352a14820b1e7140c504fa223550774c 427 SUPERFAMILY SSF63411 252 423 4.19E-15 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A21D_RS17610 352a14820b1e7140c504fa223550774c 427 Gene3D G3DSA:3.30.830.10 6 223 8.0E-49 T 28-03-2018 A21D_RS01615 0a284c02800c258b87940df5a9bbc85a 170 SUPERFAMILY SSF81301 6 169 2.88E-56 T 28-03-2018 A21D_RS01615 0a284c02800c258b87940df5a9bbc85a 170 Pfam PF04229 GrpB protein 4 163 2.9E-53 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase A21D_RS01615 0a284c02800c258b87940df5a9bbc85a 170 Gene3D G3DSA:3.30.460.10 1 170 2.2E-59 T 28-03-2018 A21D_RS15540 96f202def76ddbe8a412e7d34cfbc6d6 366 Pfam PF01926 50S ribosome-binding GTPase 161 224 7.8E-13 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS15540 96f202def76ddbe8a412e7d34cfbc6d6 366 SUPERFAMILY SSF52540 64 279 1.75E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS15540 96f202def76ddbe8a412e7d34cfbc6d6 366 Gene3D G3DSA:3.40.50.300 55 223 2.1E-33 T 28-03-2018 A21D_RS15540 96f202def76ddbe8a412e7d34cfbc6d6 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 365 1.1E-147 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH A21D_RS18440 9f9bd303578f523960f566fe4f43fe7b 128 Pfam PF11877 Protein of unknown function (DUF3397) 9 120 7.0E-21 T 28-03-2018 IPR024515 Protein of unknown function DUF3397 A21D_RS18875 d00d59c39f072fcd6ff37843baac4942 307 Gene3D G3DSA:3.40.50.300 1 307 7.7E-60 T 28-03-2018 A21D_RS18875 d00d59c39f072fcd6ff37843baac4942 307 Pfam PF02374 Anion-transporting ATPase 7 306 1.2E-79 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A21D_RS18875 d00d59c39f072fcd6ff37843baac4942 307 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 10 306 2.4E-83 T 28-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A21D_RS18875 d00d59c39f072fcd6ff37843baac4942 307 SUPERFAMILY SSF52540 5 289 9.11E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS02700 b4f1ffc412e32900c2feaa53d21a8b74 480 Pfam PF10282 Lactonase, 7-bladed beta-propeller 25 107 3.6E-12 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller A21D_RS02700 b4f1ffc412e32900c2feaa53d21a8b74 480 Pfam PF10282 Lactonase, 7-bladed beta-propeller 190 474 3.2E-56 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller A21D_RS02700 b4f1ffc412e32900c2feaa53d21a8b74 480 Gene3D G3DSA:2.130.10.10 22 479 5.2E-29 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A21D_RS02700 b4f1ffc412e32900c2feaa53d21a8b74 480 SUPERFAMILY SSF51004 203 330 1.41E-25 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A21D_RS02700 b4f1ffc412e32900c2feaa53d21a8b74 480 SUPERFAMILY SSF51004 370 461 1.41E-25 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A21D_RS00440 2ebb6194c6e938b795d135db405b2a52 662 Gene3D G3DSA:1.10.287.70 199 621 0.085 T 28-03-2018 A21D_RS00440 2ebb6194c6e938b795d135db405b2a52 662 Pfam PF02687 FtsX-like permease family 89 184 3.7E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS00440 2ebb6194c6e938b795d135db405b2a52 662 PIRSF PIRSF018968 1 662 7.0E-75 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A21D_RS12205 6e9d28cb25e27f84626f393b54dbe0f8 428 SUPERFAMILY SSF53187 4 209 1.59E-32 T 28-03-2018 A21D_RS12205 6e9d28cb25e27f84626f393b54dbe0f8 428 SUPERFAMILY SSF53187 310 375 1.59E-32 T 28-03-2018 A21D_RS12205 6e9d28cb25e27f84626f393b54dbe0f8 428 SUPERFAMILY SSF55031 194 310 1.12E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A21D_RS12205 6e9d28cb25e27f84626f393b54dbe0f8 428 Gene3D G3DSA:3.40.630.10 1 390 1.1E-28 T 28-03-2018 A21D_RS01005 0f7bfaa95633ec1ccc136f648d485ed2 96 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 59 95 1.1E-7 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) A21D_RS05685 f4804186b765fa8795c4e149474c772a 439 Gene3D G3DSA:2.40.50.100 70 305 1.3E-6 T 28-03-2018 A21D_RS05755 a2db492dc42fff71891bd9fbda78b95c 309 Pfam PF01758 Sodium Bile acid symporter family 42 220 1.3E-44 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A21D_RS00830 3f31dad9e5380dfca49cd9e079d006aa 121 Pfam PF03646 FlaG protein 20 119 8.2E-28 T 28-03-2018 IPR005186 FlaG protein A21D_RS00830 3f31dad9e5380dfca49cd9e079d006aa 121 Gene3D G3DSA:3.30.160.170 14 117 5.0E-28 T 28-03-2018 IPR005186 FlaG protein A21D_RS00830 3f31dad9e5380dfca49cd9e079d006aa 121 SUPERFAMILY SSF160214 31 121 2.48E-26 T 28-03-2018 IPR005186 FlaG protein A21D_RS01735 9a08c6618789f222b8a8d7935a609c46 311 SUPERFAMILY SSF52540 5 220 1.58E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS01735 9a08c6618789f222b8a8d7935a609c46 311 SMART SM00382 29 211 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS01735 9a08c6618789f222b8a8d7935a609c46 311 Pfam PF00005 ABC transporter 20 161 1.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS01735 9a08c6618789f222b8a8d7935a609c46 311 Gene3D G3DSA:3.40.50.300 1 272 6.2E-59 T 28-03-2018 A21D_RS01725 464b879c58b75d4298acfbde78a7ef4d 169 PIRSF PIRSF031501 5 169 2.0E-52 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 A21D_RS01725 464b879c58b75d4298acfbde78a7ef4d 169 Pfam PF06177 QueT transporter 17 162 2.6E-32 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 A21D_RS14135 5ec4c725a6bda7e9aff5080cd4d9c522 263 SUPERFAMILY SSF52540 3 217 6.78E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14135 5ec4c725a6bda7e9aff5080cd4d9c522 263 SMART SM00382 32 212 6.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS14135 5ec4c725a6bda7e9aff5080cd4d9c522 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS14135 5ec4c725a6bda7e9aff5080cd4d9c522 263 Pfam PF00005 ABC transporter 23 162 1.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS14135 5ec4c725a6bda7e9aff5080cd4d9c522 263 Gene3D G3DSA:3.40.50.300 1 229 1.4E-55 T 28-03-2018 A21D_RS11405 70852d223a19bcd705799b1d332f3236 160 SUPERFAMILY SSF52121 11 160 1.96E-62 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11405 70852d223a19bcd705799b1d332f3236 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 20 156 6.2E-59 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11405 70852d223a19bcd705799b1d332f3236 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 15 160 31.541 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11405 70852d223a19bcd705799b1d332f3236 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 20 157 4.5E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS11405 70852d223a19bcd705799b1d332f3236 160 Gene3D G3DSA:3.40.50.960 8 160 4.6E-66 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A21D_RS16945 8cb0c92274ac0021ea77d1f2c4c95e53 133 SUPERFAMILY SSF110857 2 128 7.98E-28 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like A21D_RS16945 8cb0c92274ac0021ea77d1f2c4c95e53 133 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 6 126 2.2E-20 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A21D_RS16945 8cb0c92274ac0021ea77d1f2c4c95e53 133 Gene3D G3DSA:3.10.490.10 1 133 1.3E-28 T 28-03-2018 A21D_RS13335 795daad5831f73f42faf65d84aad2c3b 122 Pfam PF07457 Protein of unknown function (DUF1516) 2 111 3.0E-32 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 A21D_RS13335 795daad5831f73f42faf65d84aad2c3b 122 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 118 1.0E-25 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 A21D_RS13335 795daad5831f73f42faf65d84aad2c3b 122 Hamap MF_01536 UPF0344 protein . 1 122 15.016 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 A21D_RS11145 20ef8edf2606d4955897773d50b73cf5 230 Pfam PF01446 Replication protein 29 134 4.0E-12 T 28-03-2018 IPR000989 Replication protein GO:0003677|GO:0005727|GO:0006260 A21D_RS07610 76fae490c7cc3d6ce9f9b3f44afe932c 113 Gene3D G3DSA:3.10.450.130 31 111 3.6E-13 T 28-03-2018 A21D_RS07610 76fae490c7cc3d6ce9f9b3f44afe932c 113 Pfam PF07252 Protein of unknown function (DUF1433) 36 104 5.2E-10 T 28-03-2018 IPR009881 Protein of unknown function DUF1433 A21D_RS18710 85cb3ce5e6e3a29237fed219d735333c 141 Gene3D G3DSA:3.40.30.10 1 141 8.0E-19 T 28-03-2018 A21D_RS18710 85cb3ce5e6e3a29237fed219d735333c 141 SUPERFAMILY SSF52833 2 137 4.31E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS18710 85cb3ce5e6e3a29237fed219d735333c 141 Pfam PF00578 AhpC/TSA family 4 122 2.2E-10 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A21D_RS10645 c9c9906e136ba39650193f9ddf6654f0 297 SUPERFAMILY SSF161098 90 277 2.75E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10645 c9c9906e136ba39650193f9ddf6654f0 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 297 8.2E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10645 c9c9906e136ba39650193f9ddf6654f0 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 72 2.1E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A21D_RS10645 c9c9906e136ba39650193f9ddf6654f0 297 Gene3D G3DSA:1.10.3720.10 24 285 1.1E-46 T 28-03-2018 A21D_RS06950 e36b62d63a363a57573d96060e2b3df8 202 Pfam PF13649 Methyltransferase domain 42 130 5.4E-10 T 28-03-2018 A21D_RS06950 e36b62d63a363a57573d96060e2b3df8 202 SUPERFAMILY SSF53335 1 175 2.61E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS06950 e36b62d63a363a57573d96060e2b3df8 202 Gene3D G3DSA:3.40.50.150 1 186 2.3E-16 T 28-03-2018 A21D_RS00850 1b70d9c4f04331485ca9131a746cf8c8 293 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 179 1.1E-53 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 A21D_RS00850 1b70d9c4f04331485ca9131a746cf8c8 293 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 1.1E-24 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A21D_RS00850 1b70d9c4f04331485ca9131a746cf8c8 293 SUPERFAMILY SSF64518 1 293 5.36E-72 T 28-03-2018 A21D_RS00850 1b70d9c4f04331485ca9131a746cf8c8 293 Gene3D G3DSA:1.20.1330.10 38 267 6.2E-38 T 28-03-2018 A21D_RS00850 1b70d9c4f04331485ca9131a746cf8c8 293 Pfam PF00700 Bacterial flagellin C-terminal helical region 210 292 4.8E-7 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A21D_RS07825 2996705802f8b4b74d37d33de4043516 407 SUPERFAMILY SSF103473 7 392 5.89E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS07825 2996705802f8b4b74d37d33de4043516 407 Pfam PF07690 Major Facilitator Superfamily 37 348 2.8E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS07825 2996705802f8b4b74d37d33de4043516 407 Gene3D G3DSA:1.20.1250.20 211 404 8.3E-20 T 28-03-2018 A21D_RS07825 2996705802f8b4b74d37d33de4043516 407 Gene3D G3DSA:1.20.1250.20 2 202 3.0E-19 T 28-03-2018 A21D_RS05015 e880902f9866f7a1e487acf7c866b17f 315 Pfam PF01966 HD domain 47 122 2.1E-10 T 28-03-2018 IPR006674 HD domain A21D_RS05015 e880902f9866f7a1e487acf7c866b17f 315 SMART SM00471 43 134 2.1E-6 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS05015 e880902f9866f7a1e487acf7c866b17f 315 Gene3D G3DSA:1.10.3210.10 1 306 1.6E-19 T 28-03-2018 A21D_RS05015 e880902f9866f7a1e487acf7c866b17f 315 SUPERFAMILY SSF109604 3 254 5.86E-30 T 28-03-2018 A21D_RS13020 909bbda48970bd296889b6f47f7cd692 257 Gene3D G3DSA:1.10.12.10 217 256 2.2E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal A21D_RS13020 909bbda48970bd296889b6f47f7cd692 257 Gene3D G3DSA:3.90.226.10 1 216 2.4E-53 T 28-03-2018 A21D_RS13020 909bbda48970bd296889b6f47f7cd692 257 SUPERFAMILY SSF52096 3 256 7.57E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A21D_RS13020 909bbda48970bd296889b6f47f7cd692 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 255 1.4E-52 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A21D_RS15170 5ff57ad4d76f7ad0432c3087d95f5d30 301 Gene3D G3DSA:3.30.70.1070 138 198 1.8E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A21D_RS15170 5ff57ad4d76f7ad0432c3087d95f5d30 301 SUPERFAMILY SSF110997 138 196 1.57E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A21D_RS01555 9930317218b845210b002f4c7c2886b7 177 Pfam PF14091 Domain of unknown function (DUF4269) 21 169 2.1E-51 T 28-03-2018 IPR025365 Protein of unknown function DUF4269 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 104 121 5.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 144 5.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 5.5E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 246 1.2E-69 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 Gene3D G3DSA:3.40.710.10 19 319 1.9E-50 T 28-03-2018 A21D_RS16405 01fc4fa6cb71320e26b56a34a544f8ea 369 SUPERFAMILY SSF56601 3 263 3.56E-65 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS16030 47b72d6933d9904a35a8b6ce7c45e45f 126 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 3 126 2.0E-5 T 28-03-2018 A21D_RS19370 5a1083ad88cb19ac92aae6dae48e6221 256 Gene3D G3DSA:3.90.850.10 29 248 3.1E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS19370 5a1083ad88cb19ac92aae6dae48e6221 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 244 3.8E-59 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS19370 5a1083ad88cb19ac92aae6dae48e6221 256 Gene3D G3DSA:2.30.30.370 1 28 1.1E-14 T 28-03-2018 A21D_RS19370 5a1083ad88cb19ac92aae6dae48e6221 256 SUPERFAMILY SSF56529 36 248 6.93E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A21D_RS19370 5a1083ad88cb19ac92aae6dae48e6221 256 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 247 2.4E-120 T 28-03-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 A21D_RS17910 50d49ed8a97afe0b24b0464f24b38ca6 151 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 70 7.0E-22 T 28-03-2018 IPR005648 Flagellar hook capping protein A21D_RS01110 0a82350f2112633b0ed3268368cd19b2 426 Gene3D G3DSA:3.40.190.10 47 168 1.4E-19 T 28-03-2018 A21D_RS01110 0a82350f2112633b0ed3268368cd19b2 426 Gene3D G3DSA:3.40.190.10 169 426 7.6E-38 T 28-03-2018 A21D_RS01110 0a82350f2112633b0ed3268368cd19b2 426 Pfam PF13416 Bacterial extracellular solute-binding protein 65 363 8.8E-42 T 28-03-2018 A21D_RS01110 0a82350f2112633b0ed3268368cd19b2 426 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 150 167 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 A21D_RS01110 0a82350f2112633b0ed3268368cd19b2 426 SUPERFAMILY SSF53850 47 414 5.98E-80 T 28-03-2018 A21D_RS16465 58516630289459ab373c73f6a7ebc5f8 354 Pfam PF14493 Helix-turn-helix domain 255 343 7.5E-23 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A21D_RS16465 58516630289459ab373c73f6a7ebc5f8 354 PIRSF PIRSF021350 2 352 4.1E-83 T 28-03-2018 IPR008308 Uncharacterised conserved protein UCP021350 A21D_RS04300 7199ea8b8c969ccbae22aa0a7f14da80 178 Gene3D G3DSA:1.20.120.450 6 153 7.3E-15 T 28-03-2018 A21D_RS04300 7199ea8b8c969ccbae22aa0a7f14da80 178 SUPERFAMILY SSF109854 13 148 1.36E-17 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A21D_RS04300 7199ea8b8c969ccbae22aa0a7f14da80 178 Pfam PF07609 Protein of unknown function (DUF1572) 4 164 2.7E-68 T 28-03-2018 IPR011466 Protein of unknown function DUF1572 A21D_RS05920 21ae8b94ee693362fabe97650a6a9a70 351 Pfam PF13303 Phosphotransferase system, EIIC 13 348 1.1E-90 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS13875 f261f222b837edbe21aef557c9cddecb 177 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 22 173 9.0E-15 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 Gene3D G3DSA:3.40.50.200 93 529 2.1E-89 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 SUPERFAMILY SSF52743 426 527 6.55E-82 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 SUPERFAMILY SSF52743 123 298 6.55E-82 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 Gene3D G3DSA:2.60.40.10 530 623 2.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 SUPERFAMILY SSF52025 335 413 3.01E-13 T 28-03-2018 A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 135 146 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 179 189 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 Pfam PF00082 Subtilase family 130 517 2.8E-68 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 464 474 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 9.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 PRINTS PR00723 Subtilisin serine protease family (S8) signature 463 479 9.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 188 9.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related A21D_RS04575 b843a6f1feb1fb5962bcf99047b1c7c8 733 Pfam PF02225 PA domain 334 403 7.6E-16 T 28-03-2018 IPR003137 PA domain A21D_RS18850 19b027192be8bde54a08bddf1f10e2cc 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 1.3E-38 T 28-03-2018 IPR005562 SpoVA A21D_RS18850 19b027192be8bde54a08bddf1f10e2cc 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.2E-48 T 28-03-2018 IPR014204 Sporulation stage V, protein AE A21D_RS00200 04596d75edabbe965029e553336661a0 70 SUPERFAMILY SSF47413 4 55 4.07E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A21D_RS00200 04596d75edabbe965029e553336661a0 70 Gene3D G3DSA:1.10.260.40 2 70 9.1E-6 T 28-03-2018 A21D_RS02825 9c641106d406189e93e68e0252a65792 199 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 184 4.4E-63 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A21D_RS02825 9c641106d406189e93e68e0252a65792 199 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 185 9.0E-61 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A21D_RS05890 74fd80057b519a24e5538356461da929 234 Gene3D G3DSA:3.40.50.80 104 230 0.018 T 28-03-2018 A21D_RS05890 74fd80057b519a24e5538356461da929 234 Gene3D G3DSA:2.40.30.10 7 99 6.4E-7 T 28-03-2018 A21D_RS05890 74fd80057b519a24e5538356461da929 234 SUPERFAMILY SSF63380 3 107 8.21E-7 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A21D_RS05890 74fd80057b519a24e5538356461da929 234 SUPERFAMILY SSF52343 108 225 1.96E-9 T 28-03-2018 A21D_RS07765 0206134de99f9adc9657858e55ab1cb3 258 Pfam PF08241 Methyltransferase domain 41 135 2.8E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS07765 0206134de99f9adc9657858e55ab1cb3 258 SUPERFAMILY SSF53335 16 228 3.72E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS07765 0206134de99f9adc9657858e55ab1cb3 258 Gene3D G3DSA:3.40.50.150 4 258 8.8E-35 T 28-03-2018 A21D_RS03255 63dbb70cf3a3df3943de52ea2c9d8bc1 123 Gene3D G3DSA:2.130.10.10 14 119 5.5E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A21D_RS17360 1068a40e3304f7487e7b3a406fb522f4 131 Gene3D G3DSA:1.10.10.10 54 128 1.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS17360 1068a40e3304f7487e7b3a406fb522f4 131 SUPERFAMILY SSF88659 65 123 1.72E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A21D_RS17360 1068a40e3304f7487e7b3a406fb522f4 131 Pfam PF07374 Protein of unknown function (DUF1492) 52 110 4.1E-5 T 28-03-2018 IPR010861 Protein of unknown function DUF1492 A21D_RS17360 1068a40e3304f7487e7b3a406fb522f4 131 Gene3D G3DSA:1.20.5.170 8 40 0.51 T 28-03-2018 A21D_RS03715 db843dfa312d84cfa148816b4e2b8e57 485 Pfam PF13520 Amino acid permease 12 431 1.9E-39 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS03715 db843dfa312d84cfa148816b4e2b8e57 485 PIRSF PIRSF006060 1 484 2.3E-55 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS15690 3660d1b6ef06783eb461fa69acf62612 177 Gene3D G3DSA:1.20.1270.60 64 173 0.0011 T 28-03-2018 A21D_RS10905 7fe0eee872e5ac636384ca4545decca7 220 SUPERFAMILY SSF50800 26 207 8.37E-48 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain A21D_RS10905 7fe0eee872e5ac636384ca4545decca7 220 Gene3D G3DSA:2.40.33.20 11 220 2.1E-27 T 28-03-2018 A21D_RS10905 7fe0eee872e5ac636384ca4545decca7 220 Pfam PF03473 MOSC domain 50 153 1.7E-12 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A21D_RS17155 d5b82967e35bb87cd995483e8aed7a5f 150 Pfam PF10747 Sporulation inhibitor of replication protein SirA 3 136 2.8E-21 T 28-03-2018 IPR019683 Sporulation inhibitor of replication protein SirA A21D_RS01345 2cf46caec0ba9f44707afd020d54f8f5 154 Gene3D G3DSA:1.20.1250.20 3 149 6.7E-6 T 28-03-2018 A21D_RS06785 4e6e2f2fe44fff52a65bf47da302c1ab 88 Gene3D G3DSA:2.30.30.100 2 76 5.3E-33 T 28-03-2018 A21D_RS06785 4e6e2f2fe44fff52a65bf47da302c1ab 88 Pfam PF06257 Biofilm formation stimulator VEG 4 74 4.2E-31 T 28-03-2018 IPR009366 Protein Veg GO:0042710 A21D_RS06785 4e6e2f2fe44fff52a65bf47da302c1ab 88 PIRSF PIRSF037257 1 85 2.4E-36 T 28-03-2018 IPR009366 Protein Veg GO:0042710 A21D_RS17625 8562dbbc7758ee27afb2acc56fa5f4cf 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 331 2.7E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A21D_RS17625 8562dbbc7758ee27afb2acc56fa5f4cf 349 Gene3D G3DSA:1.10.3470.10 2 348 9.3E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS04270 f26d5e7e167f54aebb7b0f4db32c5860 274 Pfam PF01061 ABC-2 type transporter 19 232 2.0E-21 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A21D_RS09290 664a0186f1cb21632aadca1840c8ada5 355 Pfam PF01425 Amidase 81 126 4.6E-6 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS09290 664a0186f1cb21632aadca1840c8ada5 355 SUPERFAMILY SSF75304 81 219 2.88E-10 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS09290 664a0186f1cb21632aadca1840c8ada5 355 Gene3D G3DSA:3.90.1300.10 54 327 7.3E-11 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS13140 b3a6d2e6f175d0eb27a2c7f3340a1758 473 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 67 462 4.1E-80 T 28-03-2018 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A21D_RS13140 b3a6d2e6f175d0eb27a2c7f3340a1758 473 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 470 1.1E-63 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A21D_RS10520 4cf3b20b5bb76b9640acae5f0d4723f8 442 SUPERFAMILY SSF52743 177 406 3.06E-7 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A21D_RS11315 e94626f7f784d843d2f32134961b31bf 373 Gene3D G3DSA:1.10.10.60 287 344 6.5E-6 T 28-03-2018 A21D_RS11315 e94626f7f784d843d2f32134961b31bf 373 Pfam PF05651 Putative sugar diacid recognition 10 140 7.4E-37 T 28-03-2018 IPR008599 Putative sugar diacid recognition A21D_RS11315 e94626f7f784d843d2f32134961b31bf 373 Pfam PF13556 PucR C-terminal helix-turn-helix domain 308 366 8.8E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A21D_RS11750 7b7a62ab2b2185c2bf4d9a447c092207 141 Pfam PF07885 Ion channel 50 133 5.1E-13 T 28-03-2018 IPR013099 Potassium channel domain A21D_RS11750 7b7a62ab2b2185c2bf4d9a447c092207 141 Gene3D G3DSA:1.10.287.70 18 135 1.2E-14 T 28-03-2018 A21D_RS11750 7b7a62ab2b2185c2bf4d9a447c092207 141 SUPERFAMILY SSF81324 22 132 1.28E-13 T 28-03-2018 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 18 525 2.5E-239 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 11 526 55.735 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 Gene3D G3DSA:3.40.449.10 18 210 5.7E-77 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 Gene3D G3DSA:3.90.228.20 212 291 1.6E-28 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 Gene3D G3DSA:3.90.228.20 292 524 1.9E-100 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 SUPERFAMILY SSF68923 13 211 5.23E-78 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 SUPERFAMILY SSF53795 212 525 3.2E-136 T 28-03-2018 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 PIRSF PIRSF006294 2 526 4.1E-243 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 19 480 1.9E-225 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A21D_RS14145 b9cd10625018ba4c0880eac86d8f416a 528 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 249 264 - T 28-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A21D_RS00125 146308aeabec7b9284f1e352b7159a6b 245 SUPERFAMILY SSF50249 4 176 5.65E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS00125 146308aeabec7b9284f1e352b7159a6b 245 Gene3D G3DSA:2.40.50.140 3 191 2.0E-45 T 28-03-2018 A21D_RS00125 146308aeabec7b9284f1e352b7159a6b 245 Pfam PF10991 Protein of unknown function (DUF2815) 8 183 2.4E-48 T 28-03-2018 IPR022595 Protein of unknown function DUF2815 A21D_RS14425 f2b4ffce3d16a295ced29dc29357f5e4 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A21D_RS14425 f2b4ffce3d16a295ced29dc29357f5e4 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 60 1.1E-23 T 28-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A21D_RS14425 f2b4ffce3d16a295ced29dc29357f5e4 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 40 54 - T 28-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A21D_RS00890 1d040816ea769d2c7637a0fe6efa8b99 71 Gene3D G3DSA:3.30.1050.10 2 71 4.9E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A21D_RS00890 1d040816ea769d2c7637a0fe6efa8b99 71 Pfam PF02036 SCP-2 sterol transfer family 4 62 1.4E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A21D_RS00890 1d040816ea769d2c7637a0fe6efa8b99 71 SUPERFAMILY SSF55718 8 66 2.83E-16 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A21D_RS13985 731878c724f2367e66e7dd39ff74fae7 125 SMART SM01298 14 124 7.6E-58 T 28-03-2018 IPR014916 Kinase associated protein B A21D_RS13985 731878c724f2367e66e7dd39ff74fae7 125 Pfam PF08810 Kinase associated protein B 14 124 9.1E-46 T 28-03-2018 IPR014916 Kinase associated protein B A21D_RS13985 731878c724f2367e66e7dd39ff74fae7 125 SUPERFAMILY SSF141251 5 125 1.2E-47 T 28-03-2018 A21D_RS01380 ba499fa8b4b2605a767942b32b409cd4 296 SUPERFAMILY SSF161098 53 283 1.44E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01380 ba499fa8b4b2605a767942b32b409cd4 296 Gene3D G3DSA:1.10.3720.10 10 293 9.4E-43 T 28-03-2018 A21D_RS01380 ba499fa8b4b2605a767942b32b409cd4 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 289 5.9E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS10470 0c413cfda673bcc5b83da509cdca8c9c 136 Gene3D G3DSA:3.10.450.40 10 133 2.4E-11 T 28-03-2018 A21D_RS10470 0c413cfda673bcc5b83da509cdca8c9c 136 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 21 136 2.0E-32 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 A21D_RS10470 0c413cfda673bcc5b83da509cdca8c9c 136 Pfam PF10934 Protein of unknown function (DUF2634) 24 123 2.6E-27 T 28-03-2018 IPR020288 Protein of unknown function DUF2634 A21D_RS13625 235849a598da8dad2a823df2fa33f574 235 SUPERFAMILY SSF46785 15 90 2.08E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS13625 235849a598da8dad2a823df2fa33f574 235 Gene3D G3DSA:1.10.10.10 19 104 5.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06675 92e7262e6ed19b4726f337e2b9241f94 314 SUPERFAMILY SSF56112 18 260 1.35E-25 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS06675 92e7262e6ed19b4726f337e2b9241f94 314 Gene3D G3DSA:3.30.200.20 19 113 4.7E-9 T 28-03-2018 A21D_RS06675 92e7262e6ed19b4726f337e2b9241f94 314 Gene3D G3DSA:1.10.510.10 114 297 2.7E-15 T 28-03-2018 A21D_RS06675 92e7262e6ed19b4726f337e2b9241f94 314 SMART SM00220 30 269 6.2E-7 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A21D_RS06675 92e7262e6ed19b4726f337e2b9241f94 314 Pfam PF00069 Protein kinase domain 32 263 2.4E-17 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A21D_RS09765 4b4f05e56a9a257469c7e8dc86ed8196 119 Gene3D G3DSA:3.10.129.10 1 119 1.5E-15 T 28-03-2018 A21D_RS09765 4b4f05e56a9a257469c7e8dc86ed8196 119 SUPERFAMILY SSF54637 2 114 9.61E-30 T 28-03-2018 IPR029069 HotDog domain A21D_RS12915 121bc500a33c0ca46accbab8bc11ceaa 78 Pfam PF14148 YhdB-like protein 1 70 2.7E-32 T 28-03-2018 IPR025431 YhdB-like protein A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 4.7E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 PRINTS PR00474 Glutamate 5-kinase family signature 34 48 4.7E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 4.7E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 4.7E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 SUPERFAMILY SSF53633 5 243 1.57E-62 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 Pfam PF00696 Amino acid kinase family 3 233 1.7E-49 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A21D_RS02405 e6249be89fcd873a909b6df94f3a5d90 331 Gene3D G3DSA:3.40.1160.10 2 246 9.5E-59 T 28-03-2018 A21D_RS14905 7354576ad0d29d3999c6601062f88dfe 215 Pfam PF13346 ABC-2 family transporter protein 3 210 1.4E-30 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 PIRSF PIRSF001227 15 785 1.9E-200 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Gene3D G3DSA:3.60.20.10 346 546 5.5E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Gene3D G3DSA:1.10.1400.10 547 667 1.4E-24 T 28-03-2018 A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Gene3D G3DSA:1.10.439.10 27 193 4.6E-54 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Pfam PF01804 Penicillin amidase 57 777 4.1E-215 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 SUPERFAMILY SSF56235 54 777 9.77E-219 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Gene3D G3DSA:3.60.20.10 668 780 4.7E-19 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS01295 62eaa58d552d4cd6164596ff8e34ea63 788 Gene3D G3DSA:3.60.20.10 228 339 8.8E-30 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A21D_RS03800 e94184375dbee2f2c6c757d91721c678 166 SUPERFAMILY SSF55811 2 151 4.6E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS03800 e94184375dbee2f2c6c757d91721c678 166 ProSitePatterns PS00893 Nudix box signature. 64 85 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A21D_RS03800 e94184375dbee2f2c6c757d91721c678 166 Pfam PF00293 NUDIX domain 28 138 3.8E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS03800 e94184375dbee2f2c6c757d91721c678 166 Gene3D G3DSA:3.90.79.10 1 164 1.4E-27 T 28-03-2018 A21D_RS06955 117107bfdcdc6d66cbe9a878787c135b 179 Pfam PF06042 Nucleotidyltransferase 16 176 6.1E-58 T 28-03-2018 IPR009267 Putative nucleotidyltransferase A21D_RS00375 ec0ca4e57d30abce0dedba853c8844e9 244 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 241 8.0E-36 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A21D_RS00375 ec0ca4e57d30abce0dedba853c8844e9 244 PIRSF PIRSF031509 4 244 4.2E-59 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 A21D_RS03175 010d8d1160bed23893809c3031708532 288 Gene3D G3DSA:3.30.200.20 2 91 1.8E-21 T 28-03-2018 A21D_RS03175 010d8d1160bed23893809c3031708532 288 SUPERFAMILY SSF56112 7 287 1.9E-45 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS03175 010d8d1160bed23893809c3031708532 288 PIRSF PIRSF006221 1 287 1.0E-78 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A21D_RS03175 010d8d1160bed23893809c3031708532 288 Gene3D G3DSA:3.90.1200.10 95 272 2.1E-16 T 28-03-2018 A21D_RS03175 010d8d1160bed23893809c3031708532 288 Pfam PF03881 Fructosamine kinase 6 284 3.5E-79 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A21D_RS09010 9c9bd4f71ec423112915c6bae4b1e2ae 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 28-03-2018 IPR019897 RidA, conserved site A21D_RS09010 9c9bd4f71ec423112915c6bae4b1e2ae 126 SUPERFAMILY SSF55298 2 124 2.04E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A21D_RS09010 9c9bd4f71ec423112915c6bae4b1e2ae 126 Pfam PF01042 Endoribonuclease L-PSP 8 123 7.5E-41 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family A21D_RS09010 9c9bd4f71ec423112915c6bae4b1e2ae 126 Gene3D G3DSA:3.30.1330.40 1 126 7.7E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A21D_RS09010 9c9bd4f71ec423112915c6bae4b1e2ae 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 122 3.5E-51 T 28-03-2018 IPR006056 RidA family A21D_RS13380 09de8fb00971cfdcb5d82bef7d746182 253 Pfam PF00326 Prolyl oligopeptidase family 91 238 7.6E-12 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A21D_RS13380 09de8fb00971cfdcb5d82bef7d746182 253 SUPERFAMILY SSF53474 26 252 8.32E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS13380 09de8fb00971cfdcb5d82bef7d746182 253 Gene3D G3DSA:3.40.50.1820 14 253 9.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS05715 9c83d8090cd44e0eb23fe68c5ed90c9f 219 SMART SM01007 8 184 1.3E-53 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS05715 9c83d8090cd44e0eb23fe68c5ed90c9f 219 Gene3D G3DSA:3.40.225.10 2 214 3.0E-58 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS05715 9c83d8090cd44e0eb23fe68c5ed90c9f 219 SUPERFAMILY SSF53639 3 213 1.82E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS05715 9c83d8090cd44e0eb23fe68c5ed90c9f 219 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 183 1.5E-42 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A21D_RS08585 b9dd6a8356079f9658e99282dc5ab07f 497 Gene3D G3DSA:3.30.70.1450 396 485 1.4E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS08585 b9dd6a8356079f9658e99282dc5ab07f 497 Pfam PF02080 TrkA-C domain 411 473 1.0E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS08585 b9dd6a8356079f9658e99282dc5ab07f 497 Pfam PF00999 Sodium/hydrogen exchanger family 10 382 7.3E-56 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A21D_RS08585 b9dd6a8356079f9658e99282dc5ab07f 497 SUPERFAMILY SSF116726 398 475 9.94E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 Gene3D G3DSA:3.90.1150.10 268 383 4.3E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 PIRSF PIRSF000524 1 383 1.4E-144 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 SUPERFAMILY SSF53383 5 363 5.76E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 Pfam PF00266 Aminotransferase class-V 8 340 6.0E-41 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 184 204 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A21D_RS12505 448a93fb87d4fde8765a52e044208a0c 384 Gene3D G3DSA:3.40.640.10 14 267 3.4E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS03430 f60b5853bf50e6dac6a090fa89cc41b6 132 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 1.0E-7 T 28-03-2018 A21D_RS03430 f60b5853bf50e6dac6a090fa89cc41b6 132 Gene3D G3DSA:3.10.180.10 4 132 1.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS03430 f60b5853bf50e6dac6a090fa89cc41b6 132 SUPERFAMILY SSF54593 6 131 2.48E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS14380 bb57538c0637ef3de1023c53c24b0459 143 Pfam PF13273 Protein of unknown function (DUF4064) 2 113 8.9E-15 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 A21D_RS09935 2bff8a582606d15e16b1b55ffc6d45d4 207 Pfam PF00005 ABC transporter 2 139 5.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS09935 2bff8a582606d15e16b1b55ffc6d45d4 207 Gene3D G3DSA:3.40.50.300 1 204 6.6E-48 T 28-03-2018 A21D_RS09935 2bff8a582606d15e16b1b55ffc6d45d4 207 SMART SM00382 4 188 7.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS09935 2bff8a582606d15e16b1b55ffc6d45d4 207 SUPERFAMILY SSF52540 2 199 2.61E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS05950 f2ccbb3c2031ef1e20e94c535c08c9dd 205 Gene3D G3DSA:3.40.190.10 1 204 1.7E-6 T 28-03-2018 A21D_RS06985 d180ddcf012b5cf8d7589da5b9f91909 140 Gene3D G3DSA:3.40.30.10 3 27 2.6E-4 T 28-03-2018 A21D_RS06985 d180ddcf012b5cf8d7589da5b9f91909 140 Gene3D G3DSA:3.40.30.10 28 93 4.6E-4 T 28-03-2018 A21D_RS06985 d180ddcf012b5cf8d7589da5b9f91909 140 Pfam PF04134 Protein of unknown function, DUF393 17 122 5.9E-13 T 28-03-2018 IPR007263 Protein of unknown function DUF393 A21D_RS06985 d180ddcf012b5cf8d7589da5b9f91909 140 SUPERFAMILY SSF52833 6 36 1.24E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS14635 0a1a6931f8180a7fb0311997e1090c3a 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.859 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A21D_RS14635 0a1a6931f8180a7fb0311997e1090c3a 160 Pfam PF03477 ATP cone domain 50 136 4.0E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A21D_RS14635 0a1a6931f8180a7fb0311997e1090c3a 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 8.8E-64 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A21D_RS17875 779d41a312c07bb8fd8ac443773246df 221 Pfam PF04347 Flagellar biosynthesis protein, FliO 97 160 1.4E-10 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 A21D_RS16660 2824b325689d8d190cfac8959fd92ee3 170 Pfam PF00355 Rieske [2Fe-2S] domain 85 150 2.8E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS16660 2824b325689d8d190cfac8959fd92ee3 170 Gene3D G3DSA:1.20.5.700 1 40 1.9E-17 T 28-03-2018 A21D_RS16660 2824b325689d8d190cfac8959fd92ee3 170 SUPERFAMILY SSF50022 2 161 2.75E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS16660 2824b325689d8d190cfac8959fd92ee3 170 Gene3D G3DSA:2.102.10.10 42 167 1.9E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A21D_RS15940 5568f99332a46a9d327d8922b9938742 207 Pfam PF00753 Metallo-beta-lactamase superfamily 9 189 7.9E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15940 5568f99332a46a9d327d8922b9938742 207 SMART SM00849 12 189 9.1E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15940 5568f99332a46a9d327d8922b9938742 207 Gene3D G3DSA:3.60.15.10 1 203 4.2E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS15940 5568f99332a46a9d327d8922b9938742 207 SUPERFAMILY SSF56281 1 206 2.62E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03845 ad03a4d15b41d276498c7702f9d40ec1 251 SUPERFAMILY SSF142695 74 222 1.96E-43 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A21D_RS03845 ad03a4d15b41d276498c7702f9d40ec1 251 Pfam PF00925 GTP cyclohydrolase II 75 220 1.2E-44 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A21D_RS03635 592c50e8379aa010512e834be7a98a00 501 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 481 2.5E-141 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS11540 735703e1a92aa11683d9f1e9bf662d3e 331 Hamap MF_00313 Glutaminase [glsA]. 17 331 45.347 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A21D_RS11540 735703e1a92aa11683d9f1e9bf662d3e 331 TIGRFAM TIGR03814 Gln_ase: glutaminase A 22 331 1.3E-117 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A21D_RS11540 735703e1a92aa11683d9f1e9bf662d3e 331 Gene3D G3DSA:3.40.710.10 11 331 6.4E-117 T 28-03-2018 A21D_RS11540 735703e1a92aa11683d9f1e9bf662d3e 331 Pfam PF04960 Glutaminase 35 331 7.9E-109 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A21D_RS11540 735703e1a92aa11683d9f1e9bf662d3e 331 SUPERFAMILY SSF56601 14 331 3.52E-114 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A21D_RS15685 5589e73812f11df59210b62955e513c8 331 Pfam PF12127 SigmaW regulon antibacterial 9 319 1.2E-163 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity A21D_RS15685 5589e73812f11df59210b62955e513c8 331 Hamap MF_01562 UPF0365 protein . 3 323 48.886 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity A21D_RS15685 5589e73812f11df59210b62955e513c8 331 Gene3D G3DSA:1.10.287.40 190 291 0.0013 T 28-03-2018 A21D_RS11710 fe184401d863baee26a1a5f79d93e4c3 175 Pfam PF04167 Protein of unknown function (DUF402) 60 124 1.1E-16 T 28-03-2018 IPR007295 Domain of unknown function DUF402 A21D_RS11710 fe184401d863baee26a1a5f79d93e4c3 175 PIRSF PIRSF028345 1 175 2.4E-74 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 A21D_RS11710 fe184401d863baee26a1a5f79d93e4c3 175 SUPERFAMILY SSF159234 6 171 1.57E-27 T 28-03-2018 IPR007295 Domain of unknown function DUF402 A21D_RS11710 fe184401d863baee26a1a5f79d93e4c3 175 Gene3D G3DSA:2.40.380.10 15 171 1.0E-30 T 28-03-2018 IPR007295 Domain of unknown function DUF402 A21D_RS11710 fe184401d863baee26a1a5f79d93e4c3 175 Hamap MF_01568 UPF0374 protein . 1 175 47.614 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 A21D_RS02615 92cef7ab3725d143091a26e55d02822e 480 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 61 459 8.5E-14 T 28-03-2018 A21D_RS02615 92cef7ab3725d143091a26e55d02822e 480 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 19 473 9.6E-42 T 28-03-2018 IPR029468 O-antigen polysaccharide polymerase Wzy A21D_RS06680 30d28f6c85b139cb5dae86a03bb33790 245 Gene3D G3DSA:3.40.50.410 2 95 8.9E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS06680 30d28f6c85b139cb5dae86a03bb33790 245 Gene3D G3DSA:3.40.50.410 126 241 3.5E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS06680 30d28f6c85b139cb5dae86a03bb33790 245 Pfam PF00092 von Willebrand factor type A domain 4 86 8.6E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS06680 30d28f6c85b139cb5dae86a03bb33790 245 SUPERFAMILY SSF53300 132 227 2.67E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS06680 30d28f6c85b139cb5dae86a03bb33790 245 SUPERFAMILY SSF53300 3 85 4.01E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS11205 2ffa4e752f1c3a91145543f581f47ef6 185 Gene3D G3DSA:3.40.220.10 4 185 3.0E-69 T 28-03-2018 A21D_RS11205 2ffa4e752f1c3a91145543f581f47ef6 185 Pfam PF01661 Macro domain 26 145 4.4E-43 T 28-03-2018 IPR002589 Macro domain A21D_RS11205 2ffa4e752f1c3a91145543f581f47ef6 185 SUPERFAMILY SSF52949 3 180 3.7E-61 T 28-03-2018 A21D_RS11205 2ffa4e752f1c3a91145543f581f47ef6 185 SMART SM00506 9 145 1.9E-45 T 28-03-2018 IPR002589 Macro domain A21D_RS05520 d3bbd6e9baa5c6da8a3ac48e51f4f2b7 57 Pfam PF10055 Uncharacterized small protein (DUF2292) 10 44 1.4E-14 T 28-03-2018 IPR018743 Protein of unknown function DUF2292 A21D_RS03180 c6b255931fe8645e2c7ac7919727b191 345 Pfam PF13303 Phosphotransferase system, EIIC 20 342 7.5E-104 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS14435 0971cb5ca1b4852d81eb8eaf812daa52 188 Pfam PF11167 Protein of unknown function (DUF2953) 105 156 6.3E-11 T 28-03-2018 IPR021338 Protein of unknown function DUF2953 A21D_RS08100 e788029f1cf53b22808e98c8c21b7347 208 Pfam PF01810 LysE type translocator 11 201 2.6E-43 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A21D_RS05855 adff36c798ff7b55628a45b94ba871c9 229 SUPERFAMILY SSF158911 36 164 3.14E-31 T 28-03-2018 A21D_RS05855 adff36c798ff7b55628a45b94ba871c9 229 SMART SM00725 38 162 2.5E-31 T 28-03-2018 IPR006635 NEAT domain A21D_RS05855 adff36c798ff7b55628a45b94ba871c9 229 Pfam PF05031 Iron Transport-associated domain 37 155 7.8E-30 T 28-03-2018 IPR006635 NEAT domain A21D_RS02540 4eab187ef9a10981a52cf35d5e9610c8 231 Pfam PF12698 ABC-2 family transporter protein 6 198 1.6E-9 T 28-03-2018 A21D_RS15610 4f6554361e7fcaa29498eff20da341ed 387 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 175 378 8.5E-73 T 28-03-2018 IPR010897 Sporulation stage II, protein P A21D_RS15610 4f6554361e7fcaa29498eff20da341ed 387 Gene3D G3DSA:3.40.630.40 171 380 1.4E-12 T 28-03-2018 A21D_RS15610 4f6554361e7fcaa29498eff20da341ed 387 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 94 374 9.8E-75 T 28-03-2018 IPR010897 Sporulation stage II, protein P A21D_RS13535 e3b446056d50db48929cd6b009b00c96 153 Pfam PF14153 Spore coat protein CotO 60 153 5.3E-28 T 28-03-2018 IPR025439 Spore coat protein CotO A21D_RS13535 e3b446056d50db48929cd6b009b00c96 153 Gene3D G3DSA:2.30.30.180 65 151 7.8E-4 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 SUPERFAMILY SSF63562 2 64 9.94E-22 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 63 15.07 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 Pfam PF01192 RNA polymerase Rpb6 10 61 3.4E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 Gene3D G3DSA:3.90.940.10 2 70 2.8E-21 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 SMART SM01409 9 62 8.0E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A21D_RS18210 1978bf6ad8c66e728559ec2c4c6e6a02 71 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 60 2.0E-18 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A21D_RS01460 4dc71cdacef7311ccf2e61cf611d022c 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 8.2E-45 T 28-03-2018 IPR008231 Probable chaperone CsaA A21D_RS01460 4dc71cdacef7311ccf2e61cf611d022c 109 Gene3D G3DSA:2.40.50.140 1 109 9.5E-21 T 28-03-2018 A21D_RS01460 4dc71cdacef7311ccf2e61cf611d022c 109 SUPERFAMILY SSF50249 2 108 1.76E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS01460 4dc71cdacef7311ccf2e61cf611d022c 109 Pfam PF01588 Putative tRNA binding domain 12 107 1.2E-14 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A21D_RS17365 8b80e5d9d2bc06fdd1ad9edcffa324e2 618 SUPERFAMILY SSF52540 346 486 2.02E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS17365 8b80e5d9d2bc06fdd1ad9edcffa324e2 618 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 313 581 2.6E-44 T 28-03-2018 IPR006500 DNA primase, phage/plasmid A21D_RS17365 8b80e5d9d2bc06fdd1ad9edcffa324e2 618 SUPERFAMILY SSF56747 15 100 8.5E-6 T 28-03-2018 A21D_RS17365 8b80e5d9d2bc06fdd1ad9edcffa324e2 618 Gene3D G3DSA:3.40.50.300 313 516 2.2E-17 T 28-03-2018 A21D_RS01585 b8d3d6ae1537069bf9609394b368588e 178 SUPERFAMILY SSF55729 2 165 1.72E-44 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS01585 b8d3d6ae1537069bf9609394b368588e 178 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 1.1E-29 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS01585 b8d3d6ae1537069bf9609394b368588e 178 Gene3D G3DSA:3.40.630.30 1 168 1.6E-28 T 28-03-2018 A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 SUPERFAMILY SSF51735 2 180 3.41E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 SUPERFAMILY SSF55347 130 322 3.79E-37 T 28-03-2018 A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 129 375 2.3E-35 T 28-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 Gene3D G3DSA:3.30.360.10 148 334 1.8E-33 T 28-03-2018 A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 Gene3D G3DSA:3.40.50.720 1 147 1.1E-15 T 28-03-2018 A21D_RS11495 9f939599b8048d747b1f3cbed9a8e4f0 396 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 125 1.6E-20 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A21D_RS19340 507d43f9ba0dbed7250b5f4b88c02547 149 Pfam PF03992 Antibiotic biosynthesis monooxygenase 47 120 2.7E-15 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A21D_RS19340 507d43f9ba0dbed7250b5f4b88c02547 149 SUPERFAMILY SSF54909 47 125 5.01E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS19340 507d43f9ba0dbed7250b5f4b88c02547 149 Gene3D G3DSA:3.30.70.100 39 148 2.9E-22 T 28-03-2018 A21D_RS16365 4443aad40b490da43c82212fda745a88 491 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 21 478 5.8E-156 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS16365 4443aad40b490da43c82212fda745a88 491 PIRSF PIRSF005690 5 491 1.6E-138 T 28-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A21D_RS05145 17a404d4e170f607e967f04a97898a5c 162 SUPERFAMILY SSF109854 9 159 4.03E-23 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A21D_RS05145 17a404d4e170f607e967f04a97898a5c 162 Pfam PF05163 DinB family 10 160 5.9E-11 T 28-03-2018 IPR007837 DNA damage-inducible protein DinB A21D_RS05145 17a404d4e170f607e967f04a97898a5c 162 Gene3D G3DSA:1.20.120.450 4 153 2.1E-13 T 28-03-2018 A21D_RS03095 2087a0b7c67bbe7df84105c18fa6ab5c 288 Gene3D G3DSA:3.60.15.10 5 268 4.1E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03095 2087a0b7c67bbe7df84105c18fa6ab5c 288 SMART SM00849 38 248 1.3E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03095 2087a0b7c67bbe7df84105c18fa6ab5c 288 Pfam PF00753 Metallo-beta-lactamase superfamily 36 248 6.1E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS03095 2087a0b7c67bbe7df84105c18fa6ab5c 288 SUPERFAMILY SSF56281 24 256 1.7E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase A21D_RS05030 3940565f31f83404f8e4aebe1395d11e 495 SMART SM00854 179 409 4.6E-72 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA A21D_RS05030 3940565f31f83404f8e4aebe1395d11e 495 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 179 408 1.7E-51 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA A21D_RS05030 3940565f31f83404f8e4aebe1395d11e 495 SUPERFAMILY SSF56300 179 456 3.07E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS05030 3940565f31f83404f8e4aebe1395d11e 495 Gene3D G3DSA:3.60.21.10 136 475 1.6E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS04825 4831c21274fa0d2ccd1784098899bd15 141 Pfam PF07486 Cell Wall Hydrolase 24 129 2.9E-16 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 PIRSF PIRSF002191 1 114 2.5E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 SUPERFAMILY SSF50104 2 113 1.4E-48 T 28-03-2018 IPR008991 Translation protein SH3-like domain A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 2.2E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 2.2E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 2.2E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 Pfam PF01245 Ribosomal protein L19 4 113 1.9E-53 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.273 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18035 df96bbb73d484fb871ddf9b99603ea43 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 2.4E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18465 8cf937e09d1d63295b0d12c30ca9f3ef 400 SUPERFAMILY SSF52374 1 124 6.44E-19 T 28-03-2018 A21D_RS18465 8cf937e09d1d63295b0d12c30ca9f3ef 400 SUPERFAMILY SSF52374 183 231 6.44E-19 T 28-03-2018 A21D_RS18465 8cf937e09d1d63295b0d12c30ca9f3ef 400 Pfam PF05636 HIGH Nucleotidyl Transferase 1 382 3.3E-135 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 A21D_RS18465 8cf937e09d1d63295b0d12c30ca9f3ef 400 Gene3D G3DSA:3.40.50.620 1 240 5.3E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS18465 8cf937e09d1d63295b0d12c30ca9f3ef 400 Hamap MF_01539 UPF0348 protein . 2 399 38.138 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 A21D_RS14840 270c96ed45b3aacb458df70af22d378a 146 Pfam PF13279 Thioesterase-like superfamily 25 135 1.0E-15 T 28-03-2018 A21D_RS14840 270c96ed45b3aacb458df70af22d378a 146 Gene3D G3DSA:3.10.129.10 10 145 7.6E-31 T 28-03-2018 A21D_RS14840 270c96ed45b3aacb458df70af22d378a 146 SUPERFAMILY SSF54637 18 143 1.38E-30 T 28-03-2018 IPR029069 HotDog domain A21D_RS04060 94ff345f90c4f346c4768e015f6eb6a4 307 Pfam PF03547 Membrane transport protein 149 297 7.9E-19 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A21D_RS02045 7af304d2972a5628d109167f781774f2 106 SUPERFAMILY SSF52794 2 101 8.89E-32 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02045 7af304d2972a5628d109167f781774f2 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 94 9.6E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A21D_RS02045 7af304d2972a5628d109167f781774f2 106 Gene3D G3DSA:3.40.50.2300 1 105 5.8E-35 T 28-03-2018 A21D_RS12000 d96803b2f2ceeb53b97a740cba0b8e20 266 Gene3D G3DSA:3.40.630.30 3 170 7.0E-10 T 28-03-2018 A21D_RS12000 d96803b2f2ceeb53b97a740cba0b8e20 266 Pfam PF00583 Acetyltransferase (GNAT) family 14 116 1.4E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS12000 d96803b2f2ceeb53b97a740cba0b8e20 266 SUPERFAMILY SSF55729 4 125 1.92E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS11390 a47dadb55513684a66a31261b064df44 125 SUPERFAMILY SSF57997 10 114 1.8E-5 T 28-03-2018 A21D_RS11390 a47dadb55513684a66a31261b064df44 125 Gene3D G3DSA:1.20.5.30 1 23 0.42 T 28-03-2018 A21D_RS11390 a47dadb55513684a66a31261b064df44 125 Gene3D G3DSA:1.20.1270.70 24 71 2.7E-13 T 28-03-2018 A21D_RS17345 b4eceb83978502675d7c0bf1215756db 149 Gene3D G3DSA:2.60.40.10 68 149 6.1E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A21D_RS05780 1e5071ac15e5b69f44b753efe4ab5d89 291 SUPERFAMILY SSF51695 18 276 5.58E-19 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS05780 1e5071ac15e5b69f44b753efe4ab5d89 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 24 105 5.7E-8 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS05780 1e5071ac15e5b69f44b753efe4ab5d89 291 Pfam PF16387 Domain of unknown function 171 280 2.4E-19 T 28-03-2018 IPR032160 Domain of unknown function DUF4996 A21D_RS05780 1e5071ac15e5b69f44b753efe4ab5d89 291 Gene3D G3DSA:3.20.20.190 11 285 7.9E-22 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 100 120 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 72 97 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 303 315 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 3.7E-42 T 28-03-2018 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 57 110 1.4E-12 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 3 768 6.2E-291 T 28-03-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 74 94 2.0E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 348 370 2.0E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 253 275 2.0E-5 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 Pfam PF00361 Proton-conducting membrane transporter 123 406 7.1E-69 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A21D_RS15525 c9eab2ead514c64684e6681d6dfbdb61 771 Pfam PF13244 Domain of unknown function (DUF4040) 609 673 1.7E-20 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 A21D_RS19120 f0aab042f15b9746068d71ffa3e3ab83 251 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 238 4.5E-47 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A21D_RS19120 f0aab042f15b9746068d71ffa3e3ab83 251 SUPERFAMILY SSF51695 3 241 8.37E-66 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS19120 f0aab042f15b9746068d71ffa3e3ab83 251 Gene3D G3DSA:3.20.20.190 2 250 1.1E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A21D_RS00590 47ef9b62205d527bddc2661483bc058f 252 Gene3D G3DSA:3.20.20.370 4 251 5.5E-104 T 28-03-2018 A21D_RS00590 47ef9b62205d527bddc2661483bc058f 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 247 43.769 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A21D_RS00590 47ef9b62205d527bddc2661483bc058f 252 SUPERFAMILY SSF88713 3 251 3.41E-98 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS00590 47ef9b62205d527bddc2661483bc058f 252 Pfam PF03746 LamB/YcsF family 5 242 1.2E-100 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A21D_RS13745 5dc9bd2449b2000f13ab4022c2afa005 204 Pfam PF04116 Fatty acid hydroxylase superfamily 44 184 5.1E-15 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 A21D_RS00095 9ee7b1129191dd584a9936fb95d73fcf 803 Pfam PF05272 Virulence-associated protein E 478 672 3.4E-73 T 28-03-2018 IPR007936 Virulence-associated E A21D_RS00095 9ee7b1129191dd584a9936fb95d73fcf 803 Gene3D G3DSA:3.40.50.300 457 674 1.3E-5 T 28-03-2018 A21D_RS00205 055ff072e9e3b04059c19d94232a746a 110 Gene3D G3DSA:1.10.260.40 4 110 2.4E-9 T 28-03-2018 A21D_RS09685 ada831f768eb8a131c8368902eee90a0 193 PIRSF PIRSF037394 1 191 1.7E-66 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted A21D_RS09685 ada831f768eb8a131c8368902eee90a0 193 Pfam PF09819 ABC-type cobalt transport system, permease component 7 126 1.9E-39 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted A21D_RS16025 32bf9bed43e65086904f46ac69ca8e76 297 Gene3D G3DSA:3.40.1090.10 6 294 9.6E-38 T 28-03-2018 A21D_RS16025 32bf9bed43e65086904f46ac69ca8e76 297 Pfam PF01734 Patatin-like phospholipase 6 196 4.0E-30 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A21D_RS16025 32bf9bed43e65086904f46ac69ca8e76 297 SUPERFAMILY SSF52151 6 295 6.02E-35 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 4.1E-67 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 3.8E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 PIRSF PIRSF002133 1 137 4.0E-49 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 SUPERFAMILY SSF50249 2 136 1.63E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 Gene3D G3DSA:2.40.50.140 1 137 1.6E-63 T 28-03-2018 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.669 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS06400 aafa1b5ea95fea9f6c634eccad1aebb8 137 Pfam PF00164 Ribosomal protein S12/S23 37 136 2.2E-37 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS07870 43ad188f353669b2bf820075c8c13eda 354 Gene3D G3DSA:2.60.120.380 81 182 9.2E-5 T 28-03-2018 A21D_RS08290 1f89fb409fbaf19ce851b03ac7a7d0ba 388 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 8 379 4.5E-171 T 28-03-2018 IPR014230 Sporulation protein YhbH A21D_RS08290 1f89fb409fbaf19ce851b03ac7a7d0ba 388 Gene3D G3DSA:3.40.50.410 209 388 0.0029 T 28-03-2018 IPR002035 von Willebrand factor, type A A21D_RS08290 1f89fb409fbaf19ce851b03ac7a7d0ba 388 Pfam PF04285 Protein of unknown function (DUF444) 14 186 6.3E-35 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 A21D_RS08290 1f89fb409fbaf19ce851b03ac7a7d0ba 388 Pfam PF04285 Protein of unknown function (DUF444) 190 382 3.5E-64 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 A21D_RS02995 1dc9590ea6dd98ec3cab4ff094e984d4 70 Pfam PF14168 YjzC-like protein 1 54 2.5E-26 T 28-03-2018 IPR025549 YjzC-like protein A21D_RS08750 f630b6bb6fd2345ff1e7f4ae69238f0b 261 Pfam PF00520 Ion transport protein 15 233 2.6E-42 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 A21D_RS08750 f630b6bb6fd2345ff1e7f4ae69238f0b 261 SUPERFAMILY SSF81324 14 230 1.73E-31 T 28-03-2018 A21D_RS08750 f630b6bb6fd2345ff1e7f4ae69238f0b 261 Gene3D G3DSA:1.10.287.70 13 230 5.8E-41 T 28-03-2018 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 PRINTS PR00173 Glutamate-aspartate symporter signature 335 355 2.6E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 2.6E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 PRINTS PR00173 Glutamate-aspartate symporter signature 198 217 2.6E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 PRINTS PR00173 Glutamate-aspartate symporter signature 272 298 2.6E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 SUPERFAMILY SSF118215 6 380 4.32E-82 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 Pfam PF00375 Sodium:dicarboxylate symporter family 6 379 4.9E-79 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS14220 5e559466a9b64a2d49e3ab789005ceb9 395 Gene3D G3DSA:1.10.3860.10 1 388 8.8E-65 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18765 6e0640328433bdd87392e9536454bc06 300 SUPERFAMILY SSF103481 41 139 4.32E-10 T 28-03-2018 A21D_RS18765 6e0640328433bdd87392e9536454bc06 300 Pfam PF00892 EamA-like transporter family 153 285 1.3E-27 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS18765 6e0640328433bdd87392e9536454bc06 300 Pfam PF00892 EamA-like transporter family 3 139 3.6E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS18765 6e0640328433bdd87392e9536454bc06 300 SUPERFAMILY SSF103481 187 290 1.7E-16 T 28-03-2018 A21D_RS19100 3bdd00893e29468adea0b2656f9bc8e2 85 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 4 85 2.0E-6 T 28-03-2018 A21D_RS14265 6e5571f0db7c11de07ecd8b5c644acdc 218 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 213 1.3E-59 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A21D_RS14265 6e5571f0db7c11de07ecd8b5c644acdc 218 Pfam PF02390 Putative methyltransferase 40 208 1.7E-50 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A21D_RS14265 6e5571f0db7c11de07ecd8b5c644acdc 218 Gene3D G3DSA:3.40.50.150 1 212 4.9E-37 T 28-03-2018 A21D_RS14265 6e5571f0db7c11de07ecd8b5c644acdc 218 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 213 29.214 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A21D_RS14265 6e5571f0db7c11de07ecd8b5c644acdc 218 SUPERFAMILY SSF53335 31 211 7.97E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS11280 b5e99ae1b8bcb8f27044528308fb15b5 99 Pfam PF03551 Transcriptional regulator PadR-like family 3 71 1.1E-18 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal A21D_RS11280 b5e99ae1b8bcb8f27044528308fb15b5 99 SUPERFAMILY SSF46785 3 82 5.46E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11280 b5e99ae1b8bcb8f27044528308fb15b5 99 Gene3D G3DSA:1.10.10.10 1 96 3.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01320 5f631ddbbbefcf7c89c367003b8060fc 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 3.9E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01320 5f631ddbbbefcf7c89c367003b8060fc 320 SUPERFAMILY SSF161098 90 301 1.57E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS01320 5f631ddbbbefcf7c89c367003b8060fc 320 Gene3D G3DSA:1.10.3720.10 2 307 1.6E-42 T 28-03-2018 A21D_RS01400 0b9f5543e96bc7cd76bdfca174077c61 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 9.4E-60 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A21D_RS01400 0b9f5543e96bc7cd76bdfca174077c61 329 SUPERFAMILY SSF51735 1 328 9.77E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS01400 0b9f5543e96bc7cd76bdfca174077c61 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 3.4E-133 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 A21D_RS01400 0b9f5543e96bc7cd76bdfca174077c61 329 Gene3D G3DSA:3.90.25.10 165 329 5.0E-41 T 28-03-2018 A21D_RS01400 0b9f5543e96bc7cd76bdfca174077c61 329 Gene3D G3DSA:3.40.50.720 1 164 8.3E-34 T 28-03-2018 A21D_RS17895 480f8872323f3bdd160038bfec6e6110 139 Pfam PF03748 Flagellar basal body-associated protein FliL 50 139 3.2E-7 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 A21D_RS13160 70b2630f341bc5fff5447258c2476505 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 385 1.3E-115 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A21D_RS13160 70b2630f341bc5fff5447258c2476505 403 PIRSF PIRSF037259 2 403 1.4E-121 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 SUPERFAMILY SSF52540 5 233 5.21E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 SMART SM00382 30 225 1.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 6.1E-113 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 Gene3D G3DSA:3.40.50.300 3 251 1.1E-45 T 28-03-2018 A21D_RS00240 a00165e5816e9ea29fce6fb4d821a176 261 Pfam PF00005 ABC transporter 21 173 1.8E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS17545 3dde956ed2d32a6bba85a5d2de655149 187 Pfam PF10628 Outer spore coat protein E (CotE) 7 185 2.9E-68 T 28-03-2018 IPR018901 Spore coat protein CotE A21D_RS18635 736ece0dbe11582132123fbd092321cc 287 Gene3D G3DSA:3.20.20.370 24 287 2.6E-47 T 28-03-2018 A21D_RS18635 736ece0dbe11582132123fbd092321cc 287 SUPERFAMILY SSF88713 79 281 8.68E-45 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A21D_RS18635 736ece0dbe11582132123fbd092321cc 287 Pfam PF01522 Polysaccharide deacetylase 82 204 9.0E-29 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A21D_RS11895 fa78a4259e1ea030a81a78c0e9de82d6 413 Pfam PF07690 Major Facilitator Superfamily 18 288 9.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS11895 fa78a4259e1ea030a81a78c0e9de82d6 413 Gene3D G3DSA:1.20.1250.20 2 201 2.8E-24 T 28-03-2018 A21D_RS11895 fa78a4259e1ea030a81a78c0e9de82d6 413 Gene3D G3DSA:1.20.1250.20 208 413 9.6E-16 T 28-03-2018 A21D_RS11895 fa78a4259e1ea030a81a78c0e9de82d6 413 SUPERFAMILY SSF103473 11 405 2.22E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS00180 0ccea54799559426d5d7623bff066fcf 54 ProDom PD257858 ORF59A CYTOPLASMIC SIEA-MNT 5 51 0.01 T 28-03-2018 A21D_RS00180 0ccea54799559426d5d7623bff066fcf 54 Pfam PF14168 YjzC-like protein 6 53 3.6E-16 T 28-03-2018 IPR025549 YjzC-like protein A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 PRINTS PR00344 Bacterial sensor protein C-terminal signature 25 43 5.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 PRINTS PR00344 Bacterial sensor protein C-terminal signature 9 19 5.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 PRINTS PR00344 Bacterial sensor protein C-terminal signature 49 62 5.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3 63 1.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 SUPERFAMILY SSF55874 3 63 5.89E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS07925 8bd6d641b8d3e75c3393b5277c2934a0 64 Gene3D G3DSA:3.30.565.10 2 64 6.1E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A21D_RS00755 d171a91b0f9aeeb4bc4538695c297adc 400 Gene3D G3DSA:2.30.42.10 299 367 2.6E-10 T 28-03-2018 A21D_RS00755 d171a91b0f9aeeb4bc4538695c297adc 400 SUPERFAMILY SSF50156 304 387 3.81E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A21D_RS09085 a6eddca12d6753899fdf1393294afa82 289 Gene3D G3DSA:3.40.50.1110 78 289 5.9E-35 T 28-03-2018 A21D_RS09085 a6eddca12d6753899fdf1393294afa82 289 SUPERFAMILY SSF52266 79 284 8.03E-38 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain A21D_RS09085 a6eddca12d6753899fdf1393294afa82 289 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 83 273 9.7E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 PIRSF PIRSF000090 1 257 6.6E-76 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 Gene3D G3DSA:3.40.50.620 1 257 1.4E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 SUPERFAMILY SSF52402 1 244 4.12E-75 T 28-03-2018 A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 3.7E-48 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A21D_RS14800 488d6fff43be36bd1ba452ea3e4356dc 257 SMART SM00893 21 211 5.8E-56 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A21D_RS13500 2924f4db971fa80ff0d07ccd19c58a3b 127 Gene3D G3DSA:1.10.490.10 3 127 1.5E-30 T 28-03-2018 A21D_RS13500 2924f4db971fa80ff0d07ccd19c58a3b 127 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 A21D_RS13500 2924f4db971fa80ff0d07ccd19c58a3b 127 Pfam PF01152 Bacterial-like globin 7 123 6.3E-33 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 A21D_RS13500 2924f4db971fa80ff0d07ccd19c58a3b 127 SUPERFAMILY SSF46458 7 124 2.88E-35 T 28-03-2018 IPR009050 Globin-like A21D_RS09865 cee1e17b690d5460e7606b1a44b22931 106 Gene3D G3DSA:3.40.30.10 1 106 8.3E-24 T 28-03-2018 A21D_RS09865 cee1e17b690d5460e7606b1a44b22931 106 SUPERFAMILY SSF52833 4 105 3.82E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS09865 cee1e17b690d5460e7606b1a44b22931 106 Pfam PF00085 Thioredoxin 5 102 3.5E-20 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A21D_RS11210 44d6fb2d5da9ecff29c752104ee59d1e 447 Pfam PF02447 GntP family permease 1 445 1.4E-169 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A21D_RS11210 44d6fb2d5da9ecff29c752104ee59d1e 447 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 447 2.3E-181 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A21D_RS11210 44d6fb2d5da9ecff29c752104ee59d1e 447 PIRSF PIRSF002746 1 447 6.2E-167 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A21D_RS17245 bc1b6249d73f73e0a399a8bb230e3608 93 Gene3D G3DSA:1.10.287.500 8 73 6.3E-5 T 28-03-2018 A21D_RS09915 c8d65acb74a002002820cd5e828b7b41 263 Gene3D G3DSA:1.10.3720.10 15 262 5.3E-28 T 28-03-2018 A21D_RS09915 c8d65acb74a002002820cd5e828b7b41 263 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 13 262 2.0E-86 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 A21D_RS09915 c8d65acb74a002002820cd5e828b7b41 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 254 1.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS09915 c8d65acb74a002002820cd5e828b7b41 263 SUPERFAMILY SSF161098 67 256 5.89E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07475 7e16d923a0aec17d9b90d349e6253f5a 270 SUPERFAMILY SSF69618 7 267 2.62E-42 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS07475 7e16d923a0aec17d9b90d349e6253f5a 270 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 257 2.2E-30 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A21D_RS07475 7e16d923a0aec17d9b90d349e6253f5a 270 Gene3D G3DSA:3.40.50.10090 151 262 2.2E-13 T 28-03-2018 A21D_RS07475 7e16d923a0aec17d9b90d349e6253f5a 270 Gene3D G3DSA:3.40.50.10090 48 150 1.8E-14 T 28-03-2018 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 Gene3D G3DSA:3.40.50.2300 1 124 4.7E-37 T 28-03-2018 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 2.3E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 Pfam PF00072 Response regulator receiver domain 6 116 2.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 SMART SM00862 150 225 1.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 SMART SM00448 4 115 7.3E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 SUPERFAMILY SSF52172 1 181 1.1E-40 T 28-03-2018 IPR011006 CheY-like superfamily A21D_RS09880 5e92e82ade17085d9f9839baa354c101 230 Gene3D G3DSA:1.10.10.10 125 230 6.7E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS04215 3974e13f244678f0ed784ccdca5a54fd 322 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 238 9.4E-50 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS04215 3974e13f244678f0ed784ccdca5a54fd 322 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 239 1.0E-49 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A21D_RS12345 69e416c05326c2c8f35bececa86e53a3 400 SUPERFAMILY SSF103473 6 387 2.35E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain A21D_RS12345 69e416c05326c2c8f35bececa86e53a3 400 Gene3D G3DSA:1.20.1250.20 205 398 3.7E-23 T 28-03-2018 A21D_RS12345 69e416c05326c2c8f35bececa86e53a3 400 Pfam PF07690 Major Facilitator Superfamily 16 339 4.1E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A21D_RS12345 69e416c05326c2c8f35bececa86e53a3 400 Gene3D G3DSA:1.20.1250.20 7 203 4.9E-31 T 28-03-2018 A21D_RS17740 799c8ca4c41a8ff84d313d1f6004aa44 93 Pfam PF04296 Protein of unknown function (DUF448) 10 83 1.6E-27 T 28-03-2018 IPR007393 Domain of unknown function DUF448 A21D_RS17740 799c8ca4c41a8ff84d313d1f6004aa44 93 Gene3D G3DSA:3.30.1230.10 1 93 2.7E-29 T 28-03-2018 IPR007393 Domain of unknown function DUF448 A21D_RS17740 799c8ca4c41a8ff84d313d1f6004aa44 93 SUPERFAMILY SSF64376 5 90 1.57E-28 T 28-03-2018 IPR007393 Domain of unknown function DUF448 A21D_RS10285 07091bab35a998946c6f6de0554e102a 71 Gene3D G3DSA:3.30.40.30 1 63 3.1E-12 T 28-03-2018 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 78 6.0E-26 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 79 8.1E-30 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 Gene3D G3DSA:3.30.1280.10 1 78 8.1E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 77 21.206 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 SUPERFAMILY SSF82697 3 76 1.74E-26 T 28-03-2018 A21D_RS10940 27e005cf9834845a45bf18175a0fea7e 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 76 5.0E-31 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A21D_RS01945 42a891d8a2b6db0e95354ec4c8aaf4d5 230 Gene3D G3DSA:1.20.910.10 1 222 9.8E-53 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A21D_RS01945 42a891d8a2b6db0e95354ec4c8aaf4d5 230 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 213 6.9E-67 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A21D_RS01945 42a891d8a2b6db0e95354ec4c8aaf4d5 230 Pfam PF03070 TENA/THI-4/PQQC family 14 213 4.5E-46 T 28-03-2018 IPR004305 Thiaminase-2/PQQC A21D_RS01945 42a891d8a2b6db0e95354ec4c8aaf4d5 230 SUPERFAMILY SSF48613 1 213 1.39E-64 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A21D_RS09985 874765ba44e43bd3ebec3b9bfef8b39a 489 PIRSF PIRSF026631 1 481 8.5E-123 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 A21D_RS09985 874765ba44e43bd3ebec3b9bfef8b39a 489 Pfam PF03703 Bacterial PH domain 243 327 7.4E-15 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS09985 874765ba44e43bd3ebec3b9bfef8b39a 489 Pfam PF03703 Bacterial PH domain 391 471 8.5E-8 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS09985 874765ba44e43bd3ebec3b9bfef8b39a 489 Pfam PF03703 Bacterial PH domain 61 138 1.2E-18 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS01530 ade5d60e356967e853dcf2e3140a07f4 140 Pfam PF09350 Domain of unknown function (DUF1992) 37 99 1.1E-15 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain A21D_RS07025 4c0c22772383a365100709b43ca36e11 300 SUPERFAMILY SSF161098 89 280 1.44E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS07025 4c0c22772383a365100709b43ca36e11 300 Gene3D G3DSA:1.10.3720.10 22 283 8.3E-32 T 28-03-2018 A21D_RS07025 4c0c22772383a365100709b43ca36e11 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 291 2.2E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS05285 d9ad6eda700ad71dc75931d430418207 345 Pfam PF02687 FtsX-like permease family 250 336 8.8E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 2.6E-9 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 2.6E-9 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 2.6E-9 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 PRINTS PR00758 Arsenical pump membrane protein signature 321 343 2.6E-9 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 PRINTS PR00758 Arsenical pump membrane protein signature 174 197 2.6E-9 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A21D_RS15300 8da0e5803384e7cffc8cd2cd03ee39de 430 Pfam PF03600 Citrate transporter 14 367 2.0E-49 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A21D_RS12510 63e95f6307d0e3c249231f81497f7933 253 Gene3D G3DSA:3.40.50.1000 2 236 2.0E-18 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12510 63e95f6307d0e3c249231f81497f7933 253 SUPERFAMILY SSF56784 3 244 1.72E-32 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12510 63e95f6307d0e3c249231f81497f7933 253 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 212 2.6E-18 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A21D_RS12510 63e95f6307d0e3c249231f81497f7933 253 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 232 1.8E-29 T 28-03-2018 IPR023214 HAD-like domain A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 SUPERFAMILY SSF51445 3 454 1.18E-165 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 Gene3D G3DSA:3.20.20.80 5 460 1.1E-151 T 28-03-2018 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 361 369 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 429 441 3.6E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 361 369 3.6E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 405 422 3.6E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 3.6E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 384 395 3.6E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS12420 c94cf4c365c7a65e034ad15591125958 460 Pfam PF00232 Glycosyl hydrolase family 1 5 459 1.4E-137 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A21D_RS16540 d8bef5a12a0c547f3bd393731f2e3641 294 Pfam PF14045 YIEGIA protein 8 287 3.2E-123 T 28-03-2018 IPR025918 YIEGIA protein A21D_RS16540 d8bef5a12a0c547f3bd393731f2e3641 294 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 293 3.0E-104 T 28-03-2018 A21D_RS03385 5cef45172e8961cd7ebd7008fe9f9647 153 Pfam PF00386 C1q domain 62 130 1.4E-6 T 28-03-2018 IPR001073 C1q domain A21D_RS03385 5cef45172e8961cd7ebd7008fe9f9647 153 SUPERFAMILY SSF49842 56 130 1.47E-7 T 28-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 A21D_RS03385 5cef45172e8961cd7ebd7008fe9f9647 153 Gene3D G3DSA:2.60.120.40 18 153 2.2E-22 T 28-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 A21D_RS07695 1f10b1327134b9f57967e4c168d2e0a7 53 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 2 43 4.1E-9 T 28-03-2018 IPR018728 Domain of unknown function DUF2268 A21D_RS04860 449de2b1dfe010bf698a144044e5163c 449 Pfam PF07670 Nucleoside recognition 136 234 9.0E-9 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS17390 5a473ba4d093d24abe6b3137158cc481 305 Gene3D G3DSA:3.40.30.10 91 299 0.0011 T 28-03-2018 A21D_RS17390 5a473ba4d093d24abe6b3137158cc481 305 Pfam PF13479 AAA domain 17 192 4.7E-18 T 28-03-2018 A21D_RS14195 0af6b4d7e0ec8c1daa59ebcf8cf26783 250 SUPERFAMILY SSF69318 33 124 1.7E-5 T 28-03-2018 A21D_RS11960 1b80d5a64e8cf66138cfbbdad3ee0cb6 137 Gene3D G3DSA:1.10.10.10 13 112 4.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11960 1b80d5a64e8cf66138cfbbdad3ee0cb6 137 Pfam PF01047 MarR family 26 84 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS11960 1b80d5a64e8cf66138cfbbdad3ee0cb6 137 SUPERFAMILY SSF46785 24 131 1.48E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS11960 1b80d5a64e8cf66138cfbbdad3ee0cb6 137 SMART SM00347 19 119 2.6E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A21D_RS16785 01bec370cfc3abca20b4a9b53dd1c87e 119 SUPERFAMILY SSF140415 3 116 5.23E-20 T 28-03-2018 IPR023351 YppE-like domain A21D_RS16785 01bec370cfc3abca20b4a9b53dd1c87e 119 Gene3D G3DSA:1.20.120.440 2 117 1.0E-29 T 28-03-2018 IPR023351 YppE-like domain A21D_RS16785 01bec370cfc3abca20b4a9b53dd1c87e 119 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 7 114 1.2E-24 T 28-03-2018 IPR014913 Protein of unknown function DUF1798 A21D_RS09805 9b9342908458293f1db85405ed46ef2e 94 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 1 93 1.1E-33 T 28-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 A21D_RS09805 9b9342908458293f1db85405ed46ef2e 94 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 12 82 1.1E-10 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A21D_RS16430 fd310f3b00597072a1f280041b328648 547 Pfam PF05140 ResB-like family 452 527 9.1E-17 T 28-03-2018 IPR007816 ResB-like domain A21D_RS16430 fd310f3b00597072a1f280041b328648 547 Pfam PF05140 ResB-like family 70 430 5.6E-70 T 28-03-2018 IPR007816 ResB-like domain A21D_RS16510 62a2827302b4b98e57091d84f7a50dce 277 SUPERFAMILY SSF47090 32 98 8.63E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16510 62a2827302b4b98e57091d84f7a50dce 277 Pfam PF01471 Putative peptidoglycan binding domain 43 98 1.1E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS16510 62a2827302b4b98e57091d84f7a50dce 277 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 31 277 5.4E-99 T 28-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 A21D_RS16510 62a2827302b4b98e57091d84f7a50dce 277 Pfam PF07486 Cell Wall Hydrolase 178 275 6.3E-27 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A21D_RS16510 62a2827302b4b98e57091d84f7a50dce 277 Gene3D G3DSA:1.10.101.10 32 102 1.2E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like A21D_RS09640 4d86b61cc37362d6a30dd1245eeea2ff 521 Pfam PF01564 Spermine/spermidine synthase domain 276 456 1.9E-35 T 28-03-2018 A21D_RS09640 4d86b61cc37362d6a30dd1245eeea2ff 521 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 296 309 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A21D_RS09640 4d86b61cc37362d6a30dd1245eeea2ff 521 SUPERFAMILY SSF53335 218 486 1.74E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS09640 4d86b61cc37362d6a30dd1245eeea2ff 521 Gene3D G3DSA:3.40.50.150 273 493 6.9E-42 T 28-03-2018 A21D_RS09640 4d86b61cc37362d6a30dd1245eeea2ff 521 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 221 492 24.316 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A21D_RS04910 b031e80626d9b8077ba294d19b835384 146 Gene3D G3DSA:3.40.630.30 7 138 2.3E-16 T 28-03-2018 A21D_RS04910 b031e80626d9b8077ba294d19b835384 146 SUPERFAMILY SSF55729 1 138 6.48E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS04910 b031e80626d9b8077ba294d19b835384 146 Pfam PF00583 Acetyltransferase (GNAT) family 43 133 1.0E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS01700 306ec412ee012b38ff80d79de4307761 374 SUPERFAMILY SSF58100 36 372 2.88E-37 T 28-03-2018 A21D_RS01700 306ec412ee012b38ff80d79de4307761 374 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 35 205 1.1E-29 T 28-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 A21D_RS01700 306ec412ee012b38ff80d79de4307761 374 Gene3D G3DSA:1.20.1170.10 27 373 1.5E-10 T 28-03-2018 A21D_RS04805 721dfcf8c50db94ef52989bf24bc14ef 439 SUPERFAMILY SSF109604 7 418 1.45E-119 T 28-03-2018 A21D_RS04805 721dfcf8c50db94ef52989bf24bc14ef 439 SMART SM00471 57 186 1.1E-12 T 28-03-2018 IPR003607 HD/PDEase domain A21D_RS04805 721dfcf8c50db94ef52989bf24bc14ef 439 Gene3D G3DSA:1.10.3210.10 10 312 4.8E-80 T 28-03-2018 A21D_RS04805 721dfcf8c50db94ef52989bf24bc14ef 439 Pfam PF01966 HD domain 61 179 4.2E-15 T 28-03-2018 IPR006674 HD domain A21D_RS00165 8bd07a709ec8fe99305b78f9aa8ab95f 89 SUPERFAMILY SSF140652 21 85 3.4E-14 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS00165 8bd07a709ec8fe99305b78f9aa8ab95f 89 Gene3D G3DSA:1.10.150.260 22 85 4.3E-21 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS00165 8bd07a709ec8fe99305b78f9aa8ab95f 89 Pfam PF06855 YozE SAM-like fold 23 85 4.2E-15 T 28-03-2018 IPR023089 YozE SAM-like domain A21D_RS18160 afd7f5513aa1ff28394f33ac6c74727e 27 Pfam PF08183 Stage V sporulation protein family 1 25 3.5E-16 T 28-03-2018 IPR012609 Sporulation stage V, protein M A21D_RS02325 566e3f7a42b29ca50273c4bbde9a0df3 328 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 1 311 4.1E-71 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A21D_RS02325 566e3f7a42b29ca50273c4bbde9a0df3 328 Pfam PF02378 Phosphotransferase system, EIIC 2 255 6.6E-14 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A21D_RS16070 ac91be3791d0d773d9800d7afe165d01 394 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 9 386 3.2E-124 T 28-03-2018 IPR014194 Sporulation stage III, protein AE A21D_RS16070 ac91be3791d0d773d9800d7afe165d01 394 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 72 387 1.5E-99 T 28-03-2018 IPR014194 Sporulation stage III, protein AE A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 PIRSF PIRSF036894 3 318 1.4E-131 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 Gene3D G3DSA:2.60.120.10 240 318 8.1E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 SUPERFAMILY SSF51182 3 317 1.19E-103 T 28-03-2018 IPR011051 RmlC-like cupin domain A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 109 317 3.4E-42 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 Gene3D G3DSA:2.60.120.10 1 226 3.9E-64 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A21D_RS12440 591a226074c008ec873b9dacf46bf10d 318 Pfam PF01238 Phosphomannose isomerase type I 7 317 5.1E-43 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A21D_RS02490 c70d05dfe3f64a3e3674cec0a6a7c95c 444 Pfam PF03600 Citrate transporter 16 389 1.1E-41 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A21D_RS02490 c70d05dfe3f64a3e3674cec0a6a7c95c 444 TIGRFAM TIGR00784 citMHS: citrate transporter 4 444 3.5E-104 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Gene3D G3DSA:1.20.1090.10 648 865 8.2E-67 T 28-03-2018 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 636 664 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Gene3D G3DSA:3.40.50.1970 435 647 2.0E-51 T 28-03-2018 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Pfam PF00465 Iron-containing alcohol dehydrogenase 462 849 2.2E-119 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 SUPERFAMILY SSF56796 453 864 1.3E-123 T 28-03-2018 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Pfam PF00171 Aldehyde dehydrogenase family 13 406 2.0E-24 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 PIRSF PIRSF000111 1 865 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Gene3D G3DSA:3.40.605.10 1 238 6.6E-28 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 Gene3D G3DSA:3.40.309.10 239 410 5.6E-28 T 28-03-2018 A21D_RS14180 8e775d3b09d03509e7ecfa8a696e1c6c 865 SUPERFAMILY SSF53720 15 458 1.7E-80 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A21D_RS18185 18cfadaa6e93898e0385a44aba5ae1c8 253 Pfam PF13672 Protein phosphatase 2C 12 232 5.4E-21 T 28-03-2018 A21D_RS18185 18cfadaa6e93898e0385a44aba5ae1c8 253 SUPERFAMILY SSF81606 2 242 2.09E-64 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS18185 18cfadaa6e93898e0385a44aba5ae1c8 253 SMART SM00332 1 240 1.8E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS18185 18cfadaa6e93898e0385a44aba5ae1c8 253 Gene3D G3DSA:3.60.40.10 1 242 1.6E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS18185 18cfadaa6e93898e0385a44aba5ae1c8 253 SMART SM00331 7 242 4.4E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A21D_RS13025 95297eccb3dd193d0987cb1f427d713b 61 Pfam PF14120 YhzD-like protein 1 61 7.4E-31 T 28-03-2018 IPR025544 YhzD-like protein A21D_RS13850 c89e6765202e6af7b57d4389bff3867b 257 PIRSF PIRSF021383 1 250 1.4E-51 T 28-03-2018 IPR014197 Sporulation protein YunB A21D_RS13850 c89e6765202e6af7b57d4389bff3867b 257 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 15 238 8.4E-43 T 28-03-2018 IPR014197 Sporulation protein YunB A21D_RS13850 c89e6765202e6af7b57d4389bff3867b 257 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 146 235 1.3E-28 T 28-03-2018 IPR014197 Sporulation protein YunB A21D_RS06960 cf234b28a184471637f8d14124c95e74 287 Pfam PF01636 Phosphotransferase enzyme family 20 236 3.3E-22 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase A21D_RS06960 cf234b28a184471637f8d14124c95e74 287 Gene3D G3DSA:3.90.1200.10 86 258 4.2E-22 T 28-03-2018 A21D_RS06960 cf234b28a184471637f8d14124c95e74 287 Gene3D G3DSA:3.30.200.20 2 85 2.8E-4 T 28-03-2018 A21D_RS06960 cf234b28a184471637f8d14124c95e74 287 SUPERFAMILY SSF56112 13 253 2.63E-34 T 28-03-2018 IPR011009 Protein kinase-like domain A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 Gene3D G3DSA:3.90.870.10 3 217 5.7E-79 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 212 2.0E-64 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 Pfam PF03481 Putative GTP-binding controlling metal-binding 203 339 3.4E-26 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 Pfam PF01300 Telomere recombination 26 201 1.5E-59 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 PIRSF PIRSF004930 1 343 3.8E-127 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A21D_RS04635 29551d925134a36ffd18912a5afb7524 344 SUPERFAMILY SSF55821 16 213 2.41E-66 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A21D_RS14010 f6d7d14754ae38adcd8b1d39e91c80e1 79 Pfam PF04070 Domain of unknown function (DUF378) 4 62 2.1E-25 T 28-03-2018 IPR007211 Protein of unknown function DUF378 A21D_RS18585 952dca9fa5893c95e1a6d241611ce173 203 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 10 160 1.2E-34 T 28-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ A21D_RS18585 952dca9fa5893c95e1a6d241611ce173 203 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 28 156 3.4E-13 T 28-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SUPERFAMILY SSF158911 186 298 1.7E-15 T 28-03-2018 A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SUPERFAMILY SSF158911 29 161 1.15E-38 T 28-03-2018 A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SUPERFAMILY SSF158911 348 480 2.09E-43 T 28-03-2018 A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 531 552 1.3E-4 T 28-03-2018 IPR017502 Sortase B cell surface sorting signal A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 Pfam PF05031 Iron Transport-associated domain 354 470 8.8E-38 T 28-03-2018 IPR006635 NEAT domain A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 Pfam PF05031 Iron Transport-associated domain 183 292 1.2E-16 T 28-03-2018 IPR006635 NEAT domain A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 Pfam PF05031 Iron Transport-associated domain 34 152 1.4E-32 T 28-03-2018 IPR006635 NEAT domain A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SMART SM00725 34 158 3.4E-33 T 28-03-2018 IPR006635 NEAT domain A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SMART SM00725 356 477 2.0E-43 T 28-03-2018 IPR006635 NEAT domain A21D_RS05845 e83eab1d6e5488a6e35387c11461dbdf 565 SMART SM00725 184 299 4.5E-10 T 28-03-2018 IPR006635 NEAT domain A21D_RS02740 07cf8e8f54a81ded81ea9519c642b732 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 291 3.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS02740 07cf8e8f54a81ded81ea9519c642b732 298 Gene3D G3DSA:1.10.3720.10 13 292 7.8E-35 T 28-03-2018 A21D_RS02740 07cf8e8f54a81ded81ea9519c642b732 298 SUPERFAMILY SSF161098 12 297 1.57E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS18580 3b76bdbd60401d46bea78d9bbac1144b 161 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 2 160 3.0E-38 T 28-03-2018 IPR020229 Uncharacterised protein YlaL A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 Gene3D G3DSA:3.30.70.120 116 231 9.4E-18 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 SMART SM00938 135 231 1.3E-4 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 Gene3D G3DSA:3.30.70.120 4 107 7.2E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 Pfam PF00543 Nitrogen regulatory protein P-II 135 228 5.9E-5 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 SUPERFAMILY SSF54913 9 103 5.72E-16 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A21D_RS08665 2ef57f741af8e3fe3e18642bedd9a5ab 243 SUPERFAMILY SSF54913 131 230 1.37E-19 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A21D_RS08855 826c04873ac0bed9de2d6405b5bfd62f 176 Gene3D G3DSA:3.40.50.360 1 176 1.3E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS08855 826c04873ac0bed9de2d6405b5bfd62f 176 Pfam PF03358 NADPH-dependent FMN reductase 1 128 8.6E-20 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A21D_RS08855 826c04873ac0bed9de2d6405b5bfd62f 176 SUPERFAMILY SSF52218 1 175 1.4E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain A21D_RS13565 154715a669aa5589ff9b07f82ab59ad0 141 SUPERFAMILY SSF55729 4 140 6.61E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS13565 154715a669aa5589ff9b07f82ab59ad0 141 Gene3D G3DSA:3.40.630.30 3 141 6.2E-33 T 28-03-2018 A21D_RS13565 154715a669aa5589ff9b07f82ab59ad0 141 Pfam PF13673 Acetyltransferase (GNAT) domain 29 140 1.1E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS00875 919a7781e404be8d5976282fa684df23 225 Pfam PF00156 Phosphoribosyl transferase domain 138 223 8.3E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A21D_RS00875 919a7781e404be8d5976282fa684df23 225 Gene3D G3DSA:3.40.50.2020 81 225 9.8E-22 T 28-03-2018 A21D_RS00875 919a7781e404be8d5976282fa684df23 225 SUPERFAMILY SSF53271 70 223 4.33E-19 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A21D_RS04025 a8b966db435e5947c49bfb8ed46fae1a 67 Gene3D G3DSA:2.20.25.10 3 58 7.6E-4 T 28-03-2018 A21D_RS04025 a8b966db435e5947c49bfb8ed46fae1a 67 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 5 67 5.2E-31 T 28-03-2018 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon A21D_RS14260 356fff96d4a9975643d749bd46f31051 95 Pfam PF14165 YtzH-like protein 3 89 2.5E-30 T 28-03-2018 IPR025547 YtzH-like protein A21D_RS19170 64ba72980624a023e25d3a1f66e7ca6b 91 SUPERFAMILY SSF81301 4 90 2.42E-15 T 28-03-2018 A21D_RS03310 afdfa1a4dfe878942cfadf210a6d35da 94 Pfam PF13799 Domain of unknown function (DUF4183) 23 90 2.8E-22 T 28-03-2018 IPR025237 Domain of unknown function DUF4183 A21D_RS18365 a7abeae6e068f228e69c4a5f72db6ab5 306 PIRSF PIRSF018571 1 300 3.1E-84 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A21D_RS18365 a7abeae6e068f228e69c4a5f72db6ab5 306 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 1 298 3.6E-91 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A21D_RS18365 a7abeae6e068f228e69c4a5f72db6ab5 306 Pfam PF03419 Sporulation factor SpoIIGA 2 297 7.7E-75 T 28-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A21D_RS00490 783e05d84e2e5742b5495a1130d22db5 254 Gene3D G3DSA:1.10.3720.10 11 251 1.7E-28 T 28-03-2018 A21D_RS00490 783e05d84e2e5742b5495a1130d22db5 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 246 1.1E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS00490 783e05d84e2e5742b5495a1130d22db5 254 SUPERFAMILY SSF161098 51 233 8.76E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS12065 0be931533ffd82e5e941c2219a073ede 339 SUPERFAMILY SSF69572 4 329 3.01E-79 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS12065 0be931533ffd82e5e941c2219a073ede 339 Pfam PF00899 ThiF family 6 239 1.0E-58 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A21D_RS12065 0be931533ffd82e5e941c2219a073ede 339 Gene3D G3DSA:3.40.50.720 2 244 1.3E-60 T 28-03-2018 A21D_RS18800 f4191848aa174785b5cfd0cb30449bd6 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 23 47 2.3E-9 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS18800 f4191848aa174785b5cfd0cb30449bd6 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 26 47 1.7E-11 T 28-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A21D_RS16680 5a1d1a2a3efda0c2971e44821ca44073 74 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 39 69 2.8E-9 T 28-03-2018 IPR014231 Sporulation protein YpjB A21D_RS02620 d7a5d88b4aacbb3fbd1c8ffa781e7740 407 Pfam PF01943 Polysaccharide biosynthesis protein 10 272 1.6E-19 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A21D_RS10420 fd64ab68c45ea15634a04adb164c725f 169 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 10 94 1.7E-6 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A21D_RS10420 fd64ab68c45ea15634a04adb164c725f 169 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 4 165 2.0E-59 T 28-03-2018 A21D_RS12860 5679800e1dfaeca51ae7bf02397ea207 452 PIRSF PIRSF006603 4 452 2.7E-63 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS12860 5679800e1dfaeca51ae7bf02397ea207 452 Pfam PF01554 MatE 247 408 2.3E-34 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS12860 5679800e1dfaeca51ae7bf02397ea207 452 Pfam PF01554 MatE 20 180 1.4E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS12860 5679800e1dfaeca51ae7bf02397ea207 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 2.2E-96 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A21D_RS19420 25a4f1b947577a212af85d119f272afc 208 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 206 4.0E-23 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A21D_RS19145 fefdcafba4cb9e107495143e3d6a84a8 370 Gene3D G3DSA:3.40.630.40 150 365 1.6E-17 T 28-03-2018 A21D_RS19145 fefdcafba4cb9e107495143e3d6a84a8 370 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 155 361 1.1E-68 T 28-03-2018 IPR010897 Sporulation stage II, protein P A21D_RS19145 fefdcafba4cb9e107495143e3d6a84a8 370 SUPERFAMILY SSF53187 196 360 7.12E-7 T 28-03-2018 A21D_RS19145 fefdcafba4cb9e107495143e3d6a84a8 370 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 134 356 1.0E-72 T 28-03-2018 IPR010897 Sporulation stage II, protein P A21D_RS02695 47d04b67eff049cae83b916e690abab6 116 Pfam PF08378 Nuclease-related domain 13 110 1.4E-16 T 28-03-2018 IPR011528 Nuclease-related domain, NERD A21D_RS11130 2ccf6948e12fac24eae56844dee5f18a 457 Pfam PF03553 Na+/H+ antiporter family 157 447 1.7E-49 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS11130 2ccf6948e12fac24eae56844dee5f18a 457 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 447 5.7E-119 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A21D_RS06875 f1c98f83362e342cb7112ff10261a492 63 Pfam PF10764 Inhibitor of sigma-G Gin 10 54 8.9E-16 T 28-03-2018 IPR019700 Anti-sigma-G factor Gin A21D_RS18990 96be3ac743ce1bcd846332894ce0ebb5 419 Pfam PF04143 Sulphur transport 46 410 9.2E-64 T 28-03-2018 IPR007272 Sulphur transport domain A21D_RS15320 0327501834fead9e0d46f11c31825860 108 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 78 4.1E-14 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 A21D_RS09080 383fb5008656513440750b2bbf0d9e50 206 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 12 196 3.5E-57 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 A21D_RS16950 bd8e19e2325de6eb2d3a6d7322d76169 172 Gene3D G3DSA:3.40.630.30 3 172 5.6E-34 T 28-03-2018 A21D_RS16950 bd8e19e2325de6eb2d3a6d7322d76169 172 Pfam PF13302 Acetyltransferase (GNAT) domain 5 139 8.8E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS16950 bd8e19e2325de6eb2d3a6d7322d76169 172 SUPERFAMILY SSF55729 3 163 2.7E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.0E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.0E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.0E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 SUPERFAMILY SSF143034 2 64 9.81E-23 T 28-03-2018 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 8.1E-27 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 Pfam PF01632 Ribosomal protein L35 2 62 7.1E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.686 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A21D_RS14675 0479d04e4854301ffa34e8820bdf5fab 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A21D_RS11695 d82ae5dbcc82cfee7131a292d26493be 328 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 169 1.3E-25 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A21D_RS00090 e63c4ae71af3b4ed7167399adc338a57 95 SMART SM00990 1 81 4.9E-16 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 A21D_RS10445 df7d0d6fe6a4df6851729f44f0b24fa6 149 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 12 147 1.7E-35 T 28-03-2018 IPR014986 Clostridium phage phiCD119, XkdN A21D_RS18330 42b3e9325f140fdc0dc5f5da6cdd9dc8 87 Pfam PF02325 YGGT family 9 76 5.3E-23 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 A21D_RS08125 1deebbff3d32b35753900ea1f8091a8b 497 Pfam PF03703 Bacterial PH domain 64 141 1.5E-17 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS08125 1deebbff3d32b35753900ea1f8091a8b 497 Pfam PF03703 Bacterial PH domain 261 339 1.1E-10 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS08125 1deebbff3d32b35753900ea1f8091a8b 497 Pfam PF03703 Bacterial PH domain 404 471 1.9E-8 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS08125 1deebbff3d32b35753900ea1f8091a8b 497 PIRSF PIRSF026631 1 493 6.0E-101 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 A21D_RS12200 a2d733f90a183387e61cc4d8ba02b65f 263 Pfam PF11299 Protein of unknown function (DUF3100) 18 255 1.8E-88 T 28-03-2018 IPR021450 Protein of unknown function DUF3100 A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 Pfam PF00717 Peptidase S24-like 48 101 4.6E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 Gene3D G3DSA:2.10.109.10 43 137 1.3E-10 T 28-03-2018 A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 11 168 4.7E-45 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 SUPERFAMILY SSF51306 41 118 1.41E-6 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 1.4E-6 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A21D_RS02120 35cabb18280a103ec913329741d8d90d 187 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 49 64 1.4E-6 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A21D_RS00405 d9ebc17c04aa86992f099242d2ee0115 215 Pfam PF03006 Haemolysin-III related 5 207 1.1E-44 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A21D_RS00405 d9ebc17c04aa86992f099242d2ee0115 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 7 214 1.1E-60 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 A21D_RS17255 15106885144eefe7c10a14c58baffa42 931 Gene3D G3DSA:1.20.120.330 466 618 2.9E-4 T 28-03-2018 A21D_RS17255 15106885144eefe7c10a14c58baffa42 931 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 26 324 1.2E-33 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain A21D_RS09745 b69d6a296db393a5e5551e8672c0a1d7 477 Gene3D G3DSA:3.90.350.10 135 436 7.9E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core A21D_RS09745 b69d6a296db393a5e5551e8672c0a1d7 477 Pfam PF05598 Transposase domain (DUF772) 55 123 1.9E-12 T 28-03-2018 IPR008490 Transposase InsH, N-terminal A21D_RS09745 b69d6a296db393a5e5551e8672c0a1d7 477 Pfam PF13751 Transposase DDE domain 345 462 2.8E-22 T 28-03-2018 IPR025668 Transposase DDE domain A21D_RS02355 01e2d62d965c4737d787a9633aa058a1 333 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 238 330 1.3E-43 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS02355 01e2d62d965c4737d787a9633aa058a1 333 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 6 183 9.1E-78 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS02355 01e2d62d965c4737d787a9633aa058a1 333 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 6 330 3.5E-153 T 28-03-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A21D_RS14130 82f3760cd5819b8a132a28c89f7fc095 266 SUPERFAMILY SSF161098 71 258 2.62E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS14130 82f3760cd5819b8a132a28c89f7fc095 266 Gene3D G3DSA:1.10.3720.10 24 266 5.6E-27 T 28-03-2018 A21D_RS14130 82f3760cd5819b8a132a28c89f7fc095 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 252 6.2E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A21D_RS14285 bb5950a9ea2302e664e46de10eb41e70 166 Pfam PF01931 Protein of unknown function DUF84 6 154 4.1E-40 T 28-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 A21D_RS14285 bb5950a9ea2302e664e46de10eb41e70 166 SUPERFAMILY SSF52972 1 163 4.27E-44 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A21D_RS14285 bb5950a9ea2302e664e46de10eb41e70 166 Gene3D G3DSA:3.90.950.10 1 166 1.5E-43 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A21D_RS07755 5fa1685c10e4efaf6103a49727ead4dc 116 Gene3D G3DSA:1.10.8.290 3 116 7.3E-58 T 28-03-2018 IPR023204 SP1917 domain A21D_RS07755 5fa1685c10e4efaf6103a49727ead4dc 116 PIRSF PIRSF033199 1 116 4.6E-60 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 A21D_RS07755 5fa1685c10e4efaf6103a49727ead4dc 116 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 4.4E-55 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 A21D_RS10050 f08baeb954bbc85ccd487f71f3aa362c 111 SUPERFAMILY SSF52091 10 107 5.49E-25 T 28-03-2018 IPR002645 STAS domain A21D_RS10050 f08baeb954bbc85ccd487f71f3aa362c 111 Gene3D G3DSA:3.30.750.24 3 108 1.2E-19 T 28-03-2018 IPR002645 STAS domain A21D_RS10050 f08baeb954bbc85ccd487f71f3aa362c 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 105 4.0E-25 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A21D_RS10050 f08baeb954bbc85ccd487f71f3aa362c 111 Pfam PF01740 STAS domain 8 104 7.8E-17 T 28-03-2018 IPR002645 STAS domain A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 Gene3D G3DSA:1.10.287.70 536 609 5.6E-11 T 28-03-2018 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 18 520 8.6E-209 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 Gene3D G3DSA:1.20.210.10 13 524 5.5E-198 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 470 2.9E-149 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 115 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 PRINTS PR01165 Cytochrome c oxidase subunit I signature 133 145 1.2E-108 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18545 fa4087a51f2db74e86d0845da406969f 617 SUPERFAMILY SSF81442 14 522 4.19E-183 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS00345 550f9b989740bd4d497cc489c78c7acf 502 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 48 492 3.1E-141 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS00345 550f9b989740bd4d497cc489c78c7acf 502 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 491 1.2E-174 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS01130 2e4176b3a8ea54ea2e4f0dd6f28fcab3 653 Pfam PF02538 Hydantoinase B/oxoprolinase 10 534 1.5E-143 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 A21D_RS19630 f761096e683c9d42c2254921ed092808 424 Gene3D G3DSA:2.60.520.10 24 112 0.12 T 28-03-2018 A21D_RS00595 90cd7e83f9758ef8e62e2eba61f7ed4f 413 Pfam PF01566 Natural resistance-associated macrophage protein 56 377 3.7E-24 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 A21D_RS19255 cbc20e003f56997d60494fdcbdc0bb95 281 Gene3D G3DSA:3.60.21.10 42 274 2.8E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS19255 cbc20e003f56997d60494fdcbdc0bb95 281 SUPERFAMILY SSF56300 45 272 3.24E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS19255 cbc20e003f56997d60494fdcbdc0bb95 281 Pfam PF00149 Calcineurin-like phosphoesterase 46 208 2.0E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A21D_RS13355 14a44687b7495d811a9598bd979d6509 280 PIRSF PIRSF006483 3 280 1.6E-90 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS13355 14a44687b7495d811a9598bd979d6509 280 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 3.8E-21 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS13355 14a44687b7495d811a9598bd979d6509 280 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 215 2.5E-56 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS13045 1e839451ce5051173fcf93a3b3cc260f 416 Pfam PF12698 ABC-2 family transporter protein 19 386 8.6E-61 T 28-03-2018 A21D_RS13045 1e839451ce5051173fcf93a3b3cc260f 416 Gene3D G3DSA:3.40.190.10 46 157 4.7E-23 T 28-03-2018 A21D_RS04135 f9019299c3665cd11b65301d5242f41b 313 SUPERFAMILY SSF103481 200 304 9.29E-9 T 28-03-2018 A21D_RS04135 f9019299c3665cd11b65301d5242f41b 313 SUPERFAMILY SSF103481 53 156 8.37E-13 T 28-03-2018 A21D_RS04135 f9019299c3665cd11b65301d5242f41b 313 Pfam PF00892 EamA-like transporter family 14 153 5.0E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS04135 f9019299c3665cd11b65301d5242f41b 313 Pfam PF00892 EamA-like transporter family 166 300 7.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A21D_RS10840 bfe7b61c09552bdd19893aad5853097e 501 SUPERFAMILY SSF75304 3 396 9.94E-114 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS10840 bfe7b61c09552bdd19893aad5853097e 501 SUPERFAMILY SSF75304 430 485 9.94E-114 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS10840 bfe7b61c09552bdd19893aad5853097e 501 ProSitePatterns PS00571 Amidases signature. 151 182 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A21D_RS10840 bfe7b61c09552bdd19893aad5853097e 501 Gene3D G3DSA:3.90.1300.10 2 495 5.3E-114 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS10840 bfe7b61c09552bdd19893aad5853097e 501 Pfam PF01425 Amidase 27 477 1.2E-81 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A21D_RS13865 b22e2e76ac948c73bf9e39b23bd04fae 34 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 30 1.1E-8 T 28-03-2018 IPR031596 Putative methionine and alanine importer, small subunit A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 77 1.9E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 Gene3D G3DSA:3.40.50.620 1 174 4.2E-69 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 5 282 2.7E-100 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 SUPERFAMILY SSF52374 4 281 7.32E-96 T 28-03-2018 A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 Pfam PF02569 Pantoate-beta-alanine ligase 5 280 2.8E-92 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 281 36.549 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A21D_RS02185 435c8624c2d573df4116b0083b9d8128 283 Gene3D G3DSA:3.30.1300.10 175 283 8.9E-26 T 28-03-2018 A21D_RS04080 177211f266ee362c77a337cb89bb188b 285 PIRSF PIRSF001359 2 285 2.2E-106 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04080 177211f266ee362c77a337cb89bb188b 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 284 3.6E-98 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04080 177211f266ee362c77a337cb89bb188b 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 4 285 6.1E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A21D_RS04080 177211f266ee362c77a337cb89bb188b 285 SUPERFAMILY SSF51569 5 285 8.5E-98 T 28-03-2018 A21D_RS04080 177211f266ee362c77a337cb89bb188b 285 Gene3D G3DSA:3.20.20.70 1 285 1.9E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS00010 190d10ca82945503bbc97e4ae7cf6e27 127 Pfam PF11367 Protein of unknown function (DUF3168) 7 96 5.0E-7 T 28-03-2018 IPR021508 Tail completion protein A21D_RS00220 15003b0d323e8221ae71f912c4f3b9a6 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.5E-233 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A21D_RS00220 15003b0d323e8221ae71f912c4f3b9a6 465 SUPERFAMILY SSF101960 32 462 3.01E-140 T 28-03-2018 A21D_RS00220 15003b0d323e8221ae71f912c4f3b9a6 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 5.0E-75 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A21D_RS08035 17cfd7c0f091b7bf40e4d692795ba652 202 Gene3D G3DSA:1.20.272.10 16 113 4.8E-22 T 28-03-2018 A21D_RS08035 17cfd7c0f091b7bf40e4d692795ba652 202 SUPERFAMILY SSF48019 19 198 1.64E-29 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A21D_RS04375 975532591344f30bbaa505781ee2b0cb 112 PIRSF PIRSF000699 1 109 2.0E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS04375 975532591344f30bbaa505781ee2b0cb 112 Gene3D G3DSA:1.20.58.80 5 103 1.5E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS04375 975532591344f30bbaa505781ee2b0cb 112 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 102 2.3E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS04375 975532591344f30bbaa505781ee2b0cb 112 SUPERFAMILY SSF46973 4 103 6.54E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A21D_RS09660 582cbc4d5e9ef1b9efa34a036de1bdb8 169 Pfam PF13785 Domain of unknown function (DUF4178) 27 159 3.9E-30 T 28-03-2018 IPR025235 Domain of unknown function DUF4178 A21D_RS11520 a1a667a86fd6ca405601d4c6fa86f03c 378 Pfam PF02515 CoA-transferase family III 5 372 9.4E-133 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 A21D_RS11520 a1a667a86fd6ca405601d4c6fa86f03c 378 SUPERFAMILY SSF89796 3 376 1.44E-134 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS11520 a1a667a86fd6ca405601d4c6fa86f03c 378 Gene3D G3DSA:3.40.50.10540 1 378 1.8E-148 T 28-03-2018 IPR023606 CoA-transferase family III domain A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 Pfam PF01926 50S ribosome-binding GTPase 123 222 3.9E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 Gene3D G3DSA:1.10.1580.10 180 272 1.0E-22 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 9.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 9.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 4.8E-114 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 PIRSF PIRSF006230 1 282 4.4E-104 T 28-03-2018 IPR016478 GTPase, MTG1 A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 SUPERFAMILY SSF52540 9 213 3.44E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS18025 91b74ad2c9722d930dba65c420b2f2df 282 Gene3D G3DSA:3.40.50.300 12 179 7.9E-31 T 28-03-2018 A21D_RS03875 43b51f41abfe9f61cefaa3ac36db148b 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 327 2.0E-41 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A21D_RS15870 6498be667a7d7f6d95acb808b0eb9ecb 193 Pfam PF02618 YceG-like family 132 192 1.1E-6 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A21D_RS18975 9fab88e56ef87068a5648850b72cb0c4 261 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 64 255 2.0E-47 T 28-03-2018 IPR018728 Domain of unknown function DUF2268 A21D_RS05915 2c1700d310531db324aafd6ad21b4aae 327 Pfam PF01515 Phosphate acetyl/butaryl transferase 54 286 1.4E-32 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS05915 2c1700d310531db324aafd6ad21b4aae 327 Gene3D G3DSA:3.40.50.10750 118 270 4.8E-30 T 28-03-2018 A21D_RS05915 2c1700d310531db324aafd6ad21b4aae 327 SUPERFAMILY SSF53659 16 297 4.03E-49 T 28-03-2018 A21D_RS05915 2c1700d310531db324aafd6ad21b4aae 327 PIRSF PIRSF000428 1 301 7.1E-69 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A21D_RS19635 8cae4b7091a6d23c22966b1941b2ffe7 283 Pfam PF05709 Phage tail protein 24 280 1.3E-35 T 28-03-2018 IPR008841 Siphovirus-type tail component A21D_RS05585 f71935200a023386ae9590b9ab878823 274 Gene3D G3DSA:1.20.120.20 51 212 2.8E-8 T 28-03-2018 A21D_RS03260 41b4142d162804f24cbaf73c63bf3cbf 176 Pfam PF10612 Spore coat protein Z 8 168 2.1E-33 T 28-03-2018 IPR019593 Spore coat protein Z/Y A21D_RS04400 a1b7183481a13092eff2e31de74402ef 248 Pfam PF06738 Putative threonine/serine exporter 11 246 4.2E-77 T 28-03-2018 IPR010619 Putative threonine/serine exporter A21D_RS17280 b798ebfa964c228376fc81941b58bc90 206 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 12 192 2.7E-32 T 28-03-2018 IPR006490 Phage major tail protein, phi13 family A21D_RS17280 b798ebfa964c228376fc81941b58bc90 206 Pfam PF04630 Phage tail tube protein 46 189 2.9E-9 T 28-03-2018 IPR006724 Phage tail tube protein 1 A21D_RS04470 0d9ff6a5c1fd35954883a6693fab7f68 292 Pfam PF01551 Peptidase family M23 117 214 3.5E-22 T 28-03-2018 IPR016047 Peptidase M23 A21D_RS04470 0d9ff6a5c1fd35954883a6693fab7f68 292 SUPERFAMILY SSF51261 27 217 1.94E-24 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS04470 0d9ff6a5c1fd35954883a6693fab7f68 292 Gene3D G3DSA:2.70.70.10 71 289 1.5E-30 T 28-03-2018 A21D_RS04295 17671ec84b5dde384a0950ecc27f6a72 486 Pfam PF13520 Amino acid permease 18 448 8.3E-40 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS04295 17671ec84b5dde384a0950ecc27f6a72 486 PIRSF PIRSF006060 1 484 1.5E-71 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A21D_RS11330 910ccfae24383d9815941d0ea031a234 84 Pfam PF02583 Metal-sensitive transcriptional repressor 5 80 4.1E-25 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A21D_RS09645 1ba250dc4acfcf22efb1295d0f365ddc 131 Pfam PF03994 Domain of Unknown Function (DUF350) 76 130 1.2E-14 T 28-03-2018 IPR007140 Protein of unknown function DUF350 A21D_RS09645 1ba250dc4acfcf22efb1295d0f365ddc 131 Pfam PF03994 Domain of Unknown Function (DUF350) 10 64 2.2E-14 T 28-03-2018 IPR007140 Protein of unknown function DUF350 A21D_RS12455 932dd4424d22481e1292c72c6ff94ab2 312 Gene3D G3DSA:3.90.245.10 2 312 3.0E-63 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS12455 932dd4424d22481e1292c72c6ff94ab2 312 SUPERFAMILY SSF53590 1 309 7.46E-80 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS12455 932dd4424d22481e1292c72c6ff94ab2 312 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 302 3.9E-47 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A21D_RS17220 55134a161d3a8229241b1c45d86287f3 190 Gene3D G3DSA:3.10.660.10 26 173 4.7E-4 T 28-03-2018 IPR007872 Zinc finger, DPH-type A21D_RS07345 b42766682383402e1d43867215811e28 162 Pfam PF06691 Protein of unknown function (DUF1189) 64 153 1.3E-7 T 28-03-2018 IPR009574 Protein of unknown function DUF1189 A21D_RS08865 1c0aaaad5973a009a39bb48d5f9d21ba 413 Pfam PF12698 ABC-2 family transporter protein 19 387 1.1E-39 T 28-03-2018 A21D_RS08865 1c0aaaad5973a009a39bb48d5f9d21ba 413 Gene3D G3DSA:3.40.190.10 47 156 9.7E-8 T 28-03-2018 A21D_RS14520 6bf5220fc8ff949e8824f8e39a16825b 110 Pfam PF14034 Sporulation protein YtrH 8 106 8.9E-37 T 28-03-2018 IPR025689 Sporulation protein YtrH A21D_RS18320 b22a17278471c74b9f084d400ec9a735 167 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 7.8E-18 T 28-03-2018 IPR019933 DivIVA domain A21D_RS18320 b22a17278471c74b9f084d400ec9a735 167 Pfam PF05103 DivIVA protein 3 133 5.7E-50 T 28-03-2018 IPR007793 DivIVA family A21D_RS12570 f3556794287b19c4ddd4624b3e557b1f 145 Gene3D G3DSA:3.40.1510.10 4 145 1.7E-44 T 28-03-2018 IPR015111 Hut operon regulatory protein HutP A21D_RS12570 f3556794287b19c4ddd4624b3e557b1f 145 SUPERFAMILY SSF111064 6 145 2.88E-51 T 28-03-2018 IPR015111 Hut operon regulatory protein HutP A21D_RS12570 f3556794287b19c4ddd4624b3e557b1f 145 Pfam PF09021 HutP 7 143 1.3E-33 T 28-03-2018 IPR015111 Hut operon regulatory protein HutP A21D_RS19080 b75184b09bd304e9b614657b044cd43e 83 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 6 82 1.5E-9 T 28-03-2018 IPR024962 YukD-like A21D_RS12710 9ef3e9447cde4959e5a46336e45d9a98 122 SUPERFAMILY SSF54593 7 121 9.49E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS12710 9ef3e9447cde4959e5a46336e45d9a98 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 118 2.2E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A21D_RS12710 9ef3e9447cde4959e5a46336e45d9a98 122 Gene3D G3DSA:3.10.180.10 9 122 4.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A21D_RS08725 2801dbeeccf31bb9c265be62cb8ed427 291 Gene3D G3DSA:3.30.2010.10 79 169 4.3E-18 T 28-03-2018 A21D_RS08725 2801dbeeccf31bb9c265be62cb8ed427 291 Pfam PF01435 Peptidase family M48 84 291 4.4E-36 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A21D_RS07830 ba66e7126e81bd4f124a8da8e04e0169 487 Gene3D G3DSA:3.60.110.10 230 458 1.4E-21 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A21D_RS07830 ba66e7126e81bd4f124a8da8e04e0169 487 SUPERFAMILY SSF56317 237 459 4.19E-26 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A21D_RS07830 ba66e7126e81bd4f124a8da8e04e0169 487 Pfam PF00795 Carbon-nitrogen hydrolase 277 438 4.0E-11 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A21D_RS00565 d2d51fac6e2c961eb884773737ed4cc8 103 Pfam PF08863 YolD-like protein 15 91 4.8E-18 T 28-03-2018 IPR014962 YolD-like protein A21D_RS04405 fd232f2bb1f7e5531053ef5134053ca8 147 Pfam PF12821 Threonine/Serine exporter, ThrE 5 132 6.0E-43 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE A21D_RS13880 8a8060425a529cc526bc995438b21bb3 91 PIRSF PIRSF012565 1 91 1.2E-45 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 A21D_RS13880 8a8060425a529cc526bc995438b21bb3 91 Pfam PF06265 Protein of unknown function (DUF1027) 6 87 3.9E-37 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 A21D_RS13215 e8f93763f9c191bbe69e1094f162f317 165 SUPERFAMILY SSF54909 66 161 8.05E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A21D_RS13215 e8f93763f9c191bbe69e1094f162f317 165 Pfam PF03992 Antibiotic biosynthesis monooxygenase 66 139 3.8E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A21D_RS13215 e8f93763f9c191bbe69e1094f162f317 165 Gene3D G3DSA:3.30.70.100 59 165 1.7E-26 T 28-03-2018 A21D_RS05720 57984f0b8de4e1252e8317f50899950d 350 Gene3D G3DSA:1.20.120.420 12 150 2.7E-27 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A21D_RS05720 57984f0b8de4e1252e8317f50899950d 350 Gene3D G3DSA:3.40.50.10470 151 347 1.2E-45 T 28-03-2018 A21D_RS05720 57984f0b8de4e1252e8317f50899950d 350 SUPERFAMILY SSF100950 9 343 7.03E-74 T 28-03-2018 A21D_RS05720 57984f0b8de4e1252e8317f50899950d 350 Pfam PF01008 Initiation factor 2 subunit family 74 335 1.2E-41 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A21D_RS05730 e97a53bdf811eb66f5f3c2db58152a08 442 Pfam PF03553 Na+/H+ antiporter family 246 430 8.5E-12 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS05730 e97a53bdf811eb66f5f3c2db58152a08 442 Pfam PF03553 Na+/H+ antiporter family 33 220 1.3E-11 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A21D_RS05670 03813d242720777a4939f14e6109d951 138 Gene3D G3DSA:1.20.1480.30 21 136 0.0011 T 28-03-2018 A21D_RS05670 03813d242720777a4939f14e6109d951 138 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 92 2.0E-20 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 A21D_RS17550 be3ecded1eae28af464b16ea7054011a 142 PIRSF PIRSF021287 1 123 4.1E-45 T 28-03-2018 IPR016783 Biofilm formation YmcA A21D_RS17550 be3ecded1eae28af464b16ea7054011a 142 SUPERFAMILY SSF158622 4 123 3.01E-29 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS17550 be3ecded1eae28af464b16ea7054011a 142 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 1.8E-19 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A21D_RS17550 be3ecded1eae28af464b16ea7054011a 142 Gene3D G3DSA:1.20.1500.10 8 116 1.4E-26 T 28-03-2018 IPR023378 YheA/YmcA-like domain A21D_RS03820 06d70168aeffa37025b69c08f3d59563 452 Pfam PF05525 Branched-chain amino acid transport protein 9 438 3.2E-152 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A21D_RS03820 06d70168aeffa37025b69c08f3d59563 452 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 429 1.5E-140 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A21D_RS08675 7f3111f2f8a3a41ed8ca6947f32c7b2e 230 Pfam PF07556 Protein of unknown function (DUF1538) 18 228 5.6E-74 T 28-03-2018 IPR011435 Protein of unknown function DUF1538 A21D_RS01235 74a06db1497cffea1f58654b26dcd32c 175 Pfam PF02417 Chromate transporter 4 170 8.8E-35 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A21D_RS08575 30805c9941a108c4f4b84c66419c415c 127 Pfam PF14150 YesK-like protein 49 123 2.3E-7 T 28-03-2018 IPR025434 YesK-like protein A21D_RS14480 0ccfa4365bd7c720a18f8ffd5974bb00 351 Pfam PF01478 Type IV leader peptidase family 202 305 1.0E-15 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A21D_RS14480 0ccfa4365bd7c720a18f8ffd5974bb00 351 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 109 188 1.9E-24 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal A21D_RS19150 c143ba5f9f4e592b38309f998224c732 178 Gene3D G3DSA:2.40.50.140 93 174 1.2E-15 T 28-03-2018 A21D_RS10210 fbff6ec3e16a4093fe5d451c82dc0dd2 66 Pfam PF14146 Domain of unknown function (DUF4305) 19 54 1.5E-12 T 28-03-2018 IPR025426 Protein of unknown function DUF4305 A21D_RS10210 fbff6ec3e16a4093fe5d451c82dc0dd2 66 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 4 65 2.0E-6 T 28-03-2018 A21D_RS16655 8cc2de7f90523ff27f71fcbd01519bd0 152 Pfam PF10673 Protein of unknown function (DUF2487) 10 152 3.0E-42 T 28-03-2018 IPR019615 Protein of unknown function DUF2487 A21D_RS03445 46998afa58ac1c46e940fe0e65c2c4ab 370 Pfam PF00266 Aminotransferase class-V 3 361 1.6E-62 T 28-03-2018 IPR000192 Aminotransferase class V domain A21D_RS03445 46998afa58ac1c46e940fe0e65c2c4ab 370 PIRSF PIRSF005572 1 370 1.0E-105 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A21D_RS03445 46998afa58ac1c46e940fe0e65c2c4ab 370 Gene3D G3DSA:3.40.640.10 10 253 3.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A21D_RS03445 46998afa58ac1c46e940fe0e65c2c4ab 370 SUPERFAMILY SSF53383 1 369 1.5E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A21D_RS03445 46998afa58ac1c46e940fe0e65c2c4ab 370 Gene3D G3DSA:3.90.1150.10 257 370 5.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A21D_RS07650 8a47ffdf065552c6c4eaa0812aac88da 118 Gene3D G3DSA:3.10.450.130 33 116 8.9E-16 T 28-03-2018 A21D_RS07650 8a47ffdf065552c6c4eaa0812aac88da 118 Pfam PF07252 Protein of unknown function (DUF1433) 38 94 1.4E-11 T 28-03-2018 IPR009881 Protein of unknown function DUF1433 A21D_RS05490 86a2bb12ef6ba9fdf9638aeeceb6636f 138 Gene3D G3DSA:1.10.10.10 1 136 7.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS01625 936e9b7cb7b42a045c20f9f52cd6ce5b 467 PIRSF PIRSF006446 1 462 1.3E-186 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A21D_RS01625 936e9b7cb7b42a045c20f9f52cd6ce5b 467 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 443 7.7E-175 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A21D_RS12540 2af574ee4a98736f2b2596dc7d5250f4 441 Pfam PF07670 Nucleoside recognition 131 229 9.7E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS00030 14f27b5fa58555735c84851d1a2191b5 377 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 25 232 3.9E-14 T 28-03-2018 IPR024455 Phage capsid A21D_RS00030 14f27b5fa58555735c84851d1a2191b5 377 SUPERFAMILY SSF56563 90 367 4.18E-17 T 28-03-2018 A21D_RS00030 14f27b5fa58555735c84851d1a2191b5 377 Gene3D G3DSA:3.30.2400.10 116 248 1.5E-12 T 28-03-2018 A21D_RS00030 14f27b5fa58555735c84851d1a2191b5 377 Pfam PF05065 Phage capsid family 90 295 1.3E-12 T 28-03-2018 IPR024455 Phage capsid A21D_RS05465 b59c4830047308122aa10bf5247efd44 181 Pfam PF05709 Phage tail protein 46 165 5.5E-18 T 28-03-2018 IPR008841 Siphovirus-type tail component A21D_RS05465 b59c4830047308122aa10bf5247efd44 181 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 25 153 7.3E-16 T 28-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal A21D_RS02210 dc62f6390b56cfedcaf573e8b4d99224 254 SUPERFAMILY SSF53335 28 214 7.88E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS02210 dc62f6390b56cfedcaf573e8b4d99224 254 Gene3D G3DSA:3.40.50.150 26 251 2.0E-25 T 28-03-2018 A21D_RS02210 dc62f6390b56cfedcaf573e8b4d99224 254 Pfam PF13649 Methyltransferase domain 43 137 6.0E-17 T 28-03-2018 A21D_RS18790 e5f7c7480c34de7529e317d223a9c735 385 Gene3D G3DSA:1.25.40.10 57 267 4.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS06010 08689793ae601fe04aa15b130629a280 337 Pfam PF01497 Periplasmic binding protein 63 314 2.8E-31 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A21D_RS06010 08689793ae601fe04aa15b130629a280 337 Gene3D G3DSA:3.40.50.1980 171 337 7.1E-28 T 28-03-2018 A21D_RS06010 08689793ae601fe04aa15b130629a280 337 Gene3D G3DSA:3.40.50.1980 30 170 1.2E-21 T 28-03-2018 A21D_RS06010 08689793ae601fe04aa15b130629a280 337 SUPERFAMILY SSF53807 42 321 3.61E-49 T 28-03-2018 A21D_RS07350 a5f197b5fa7ed5b303d87db194877a5c 317 Pfam PF09991 Predicted membrane protein (DUF2232) 20 306 7.7E-63 T 28-03-2018 IPR018710 Protein of unknown function DUF2232 A21D_RS07615 f6064fd7532d5f2c2759f2d620b603b3 464 SUPERFAMILY SSF53474 10 97 5.4E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07615 f6064fd7532d5f2c2759f2d620b603b3 464 SUPERFAMILY SSF53474 176 297 5.4E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07615 f6064fd7532d5f2c2759f2d620b603b3 464 Gene3D G3DSA:3.40.50.1820 5 321 7.1E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS07615 f6064fd7532d5f2c2759f2d620b603b3 464 Pfam PF01764 Lipase (class 3) 182 260 1.7E-4 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A21D_RS18525 117f225ae433a751bf167766ccfd9a84 151 Gene3D G3DSA:1.20.120.80 1 137 6.0E-13 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A21D_RS18525 117f225ae433a751bf167766ccfd9a84 151 Pfam PF04238 Protein of unknown function (DUF420) 4 132 1.5E-37 T 28-03-2018 IPR007352 Protein of unknown function DUF420 A21D_RS09995 ad3ae67d8a185509a1d750bb245a5115 256 Pfam PF01694 Rhomboid family 56 195 1.9E-35 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS09995 ad3ae67d8a185509a1d750bb245a5115 256 SUPERFAMILY SSF144091 16 194 1.96E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS09995 ad3ae67d8a185509a1d750bb245a5115 256 Gene3D G3DSA:1.20.1540.10 14 195 7.2E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A21D_RS07630 246e3f6371680733bacacf42ec9d74b2 331 PIRSF PIRSF015268 1 331 3.0E-150 T 28-03-2018 IPR011204 Virulence protein RhuM-like A21D_RS07630 246e3f6371680733bacacf42ec9d74b2 331 Pfam PF13310 Virulence protein RhuM family 63 312 1.3E-121 T 28-03-2018 IPR011204 Virulence protein RhuM-like A21D_RS18560 2a0117d3d30dea4c1cbcfb49e471c42b 317 Pfam PF02628 Cytochrome oxidase assembly protein 54 288 4.5E-31 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A21D_RS18560 2a0117d3d30dea4c1cbcfb49e471c42b 317 Hamap MF_01664 Heme A synthase [ctaA]. 1 304 28.703 T 28-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 A21D_RS18520 c4f228bf99d941bbe3dba72b7d0efeca 352 Pfam PF01594 AI-2E family transporter 12 343 4.5E-65 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A21D_RS18520 c4f228bf99d941bbe3dba72b7d0efeca 352 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 12 346 7.0E-103 T 28-03-2018 IPR014227 Sporulation integral membrane protein YtvI A21D_RS03130 e4180e6ecc2bcd0d54485c202d851bfb 170 SUPERFAMILY SSF55729 105 158 8.13E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS07285 560326af1196496302a8ea7c00b2c2dd 235 Pfam PF04474 Protein of unknown function (DUF554) 5 227 6.2E-75 T 28-03-2018 IPR007563 Protein of unknown function DUF554 A21D_RS11340 fa455b0835979e0e5f093a7dbb3da2df 117 SUPERFAMILY SSF52821 9 104 1.3E-6 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS11340 fa455b0835979e0e5f093a7dbb3da2df 117 Gene3D G3DSA:3.40.250.10 24 110 1.3E-4 T 28-03-2018 IPR001763 Rhodanese-like domain A21D_RS06085 711f805dbeaa6f765f6ee05c79277353 626 PIRSF PIRSF018968 1 621 2.3E-131 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A21D_RS06085 711f805dbeaa6f765f6ee05c79277353 626 Pfam PF02687 FtsX-like permease family 84 174 3.2E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A21D_RS08990 00add8874c01e3994a0ef5e44eeac4b8 391 Pfam PF01168 Alanine racemase, N-terminal domain 17 263 4.5E-14 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A21D_RS08990 00add8874c01e3994a0ef5e44eeac4b8 391 Gene3D G3DSA:3.20.20.10 18 270 1.7E-36 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS08990 00add8874c01e3994a0ef5e44eeac4b8 391 SUPERFAMILY SSF51419 17 279 2.62E-22 T 28-03-2018 IPR029066 PLP-binding barrel A21D_RS00720 b0b8f3cd546e955533792a3c093a1328 64 Pfam PF04024 PspC domain 2 59 8.5E-21 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal A21D_RS14700 b0cd18256ab75cc7e15a8929a5ce2db2 161 PIRSF PIRSF030140 1 161 5.7E-54 T 28-03-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 A21D_RS14700 b0cd18256ab75cc7e15a8929a5ce2db2 161 SUPERFAMILY SSF101386 2 161 8.83E-43 T 28-03-2018 A21D_RS14700 b0cd18256ab75cc7e15a8929a5ce2db2 161 Pfam PF08761 dUTPase 2 161 2.0E-48 T 28-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 A21D_RS14700 b0cd18256ab75cc7e15a8929a5ce2db2 161 Gene3D G3DSA:1.10.4010.10 1 161 5.8E-43 T 28-03-2018 A21D_RS15950 cc792d9ac0ee1cf62292480cc702988f 123 Pfam PF14173 ComG operon protein 7 37 114 7.5E-7 T 28-03-2018 IPR020372 Competence operon G protein 7, ComGG A21D_RS01240 099cedf01e637344daa5cc9db9eeaa7b 193 Pfam PF02417 Chromate transporter 5 169 8.6E-36 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A21D_RS07645 32163601921eb08fee638b943f974637 146 Pfam PF07486 Cell Wall Hydrolase 24 133 1.9E-15 T 28-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A21D_RS08130 68acafb282c51b135383af852f47739f 165 Pfam PF03703 Bacterial PH domain 81 154 1.9E-12 T 28-03-2018 IPR005182 Domain of unknown function DUF304 A21D_RS14855 94dbbb9fe0ccf978a99250fba58c5df4 353 SUPERFAMILY SSF53335 161 264 1.58E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS14855 94dbbb9fe0ccf978a99250fba58c5df4 353 SUPERFAMILY SSF53335 22 125 1.58E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS14855 94dbbb9fe0ccf978a99250fba58c5df4 353 Pfam PF13847 Methyltransferase domain 56 242 5.3E-21 T 28-03-2018 IPR025714 Methyltransferase domain A21D_RS14855 94dbbb9fe0ccf978a99250fba58c5df4 353 Gene3D G3DSA:3.40.50.150 1 349 4.8E-31 T 28-03-2018 A21D_RS01920 c39627104a1ba50072c5873b0fe379b4 158 SUPERFAMILY SSF55804 3 152 2.35E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS01920 c39627104a1ba50072c5873b0fe379b4 158 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 151 4.2E-32 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A21D_RS01920 c39627104a1ba50072c5873b0fe379b4 158 Gene3D G3DSA:3.40.930.10 1 153 1.2E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A21D_RS11295 a5a7f0b00bbaab6520ea82cfa88e2584 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 3.9E-8 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A21D_RS16775 4df5993ea114e935a421466c7a07a694 328 Pfam PF10720 Protein of unknown function (DUF2515) 12 311 1.1E-112 T 28-03-2018 IPR019658 Protein of unknown function DUF2515 A21D_RS00300 87dd6628f7ca77763c8f9995c3a4eec9 251 SUPERFAMILY SSF52540 4 220 6.61E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS00300 87dd6628f7ca77763c8f9995c3a4eec9 251 SMART SM00382 30 226 8.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A21D_RS00300 87dd6628f7ca77763c8f9995c3a4eec9 251 Pfam PF00005 ABC transporter 21 169 5.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A21D_RS00300 87dd6628f7ca77763c8f9995c3a4eec9 251 Gene3D G3DSA:3.40.50.300 1 239 3.3E-60 T 28-03-2018 A21D_RS00300 87dd6628f7ca77763c8f9995c3a4eec9 251 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A21D_RS06860 628f160e0e59ebe3edaccbf937ebcea8 109 Gene3D G3DSA:3.30.70.120 1 108 3.6E-13 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A21D_RS06860 628f160e0e59ebe3edaccbf937ebcea8 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 1.3E-53 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor A21D_RS06860 628f160e0e59ebe3edaccbf937ebcea8 109 SUPERFAMILY SSF54913 2 107 1.43E-11 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A21D_RS03930 4b99d1ba47b2141164d9a9c2e15fa96f 265 Pfam PF13349 Putative adhesin 124 263 1.7E-17 T 28-03-2018 IPR025164 Putative adhesin A21D_RS06160 e2757e29732f893cc6f69e927efe1a8a 63 Pfam PF14206 Cysteine-rich CPCC 3 52 2.0E-17 T 28-03-2018 IPR025983 Cysteine-rich CPCC domain A21D_RS12250 04cb6d189ac4a52c00a4275c102838a3 126 SUPERFAMILY SSF69118 3 123 2.16E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A21D_RS12250 04cb6d189ac4a52c00a4275c102838a3 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 31 115 4.6E-15 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A21D_RS12250 04cb6d189ac4a52c00a4275c102838a3 126 Gene3D G3DSA:1.20.1290.10 3 125 3.3E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A21D_RS16475 4d357339ac9a376abfa059d95ecf2cd0 194 Pfam PF02517 CAAX protease self-immunity 95 179 8.7E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A21D_RS05895 bc3912471e2e4efb747c35abfda6bf26 171 Gene3D G3DSA:3.40.190.10 1 171 8.6E-6 T 28-03-2018 A21D_RS13495 e85839c5b06e0d877c8a36fc2a1471cd 296 Pfam PF13743 Thioredoxin 32 222 1.7E-68 T 28-03-2018 A21D_RS13495 e85839c5b06e0d877c8a36fc2a1471cd 296 SUPERFAMILY SSF52833 27 233 3.0E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold A21D_RS13495 e85839c5b06e0d877c8a36fc2a1471cd 296 Gene3D G3DSA:3.40.30.10 27 237 4.4E-25 T 28-03-2018 A21D_RS11770 e35edb84ade7715a3a1284e888d50f88 131 Hamap MF_01502 UPF0295 protein . 4 118 35.115 T 28-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A21D_RS11770 e35edb84ade7715a3a1284e888d50f88 131 Pfam PF11023 Zinc-ribbon containing domain 7 115 2.1E-55 T 28-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A21D_RS11770 e35edb84ade7715a3a1284e888d50f88 131 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 7 116 3.0E-45 T 28-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A21D_RS06845 c5b518591ecb757152c8c69c8fb479ce 274 Pfam PF04468 PSP1 C-terminal conserved region 61 146 5.2E-32 T 28-03-2018 IPR007557 PSP1, C-terminal A21D_RS12660 8910b10af0bf7ca15ebef566ea77eb94 304 Pfam PF00682 HMGL-like 11 278 1.5E-46 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A21D_RS12660 8910b10af0bf7ca15ebef566ea77eb94 304 Gene3D G3DSA:3.20.20.70 2 299 6.4E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A21D_RS12660 8910b10af0bf7ca15ebef566ea77eb94 304 SUPERFAMILY SSF51569 3 290 1.26E-69 T 28-03-2018 A21D_RS04760 638afb453cc22a96770e31b16cf12388 203 Pfam PF04854 Protein of unknown function, DUF624 18 93 3.5E-28 T 28-03-2018 IPR006938 Protein of unknown function DUF624 A21D_RS08480 4acd569edc7e0ca283e4170638157c4e 217 Pfam PF07947 YhhN family 29 205 1.3E-33 T 28-03-2018 IPR012506 YhhN-like GO:0016021 A21D_RS03350 c09936db37610ad1880d90c868f8d9d0 133 Pfam PF11457 Protein of unknown function (DUF3021) 5 131 5.4E-20 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 A21D_RS19510 6b8cc486fbda857c078e1195b95eb20d 305 Pfam PF14257 Domain of unknown function (DUF4349) 17 290 1.1E-67 T 28-03-2018 IPR025645 Domain of unknown function DUF4349 A21D_RS12305 a6911c617f1f554571849afbb3a2b7fc 277 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 211 2.1E-61 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS12305 a6911c617f1f554571849afbb3a2b7fc 277 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 269 1.9E-20 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS12305 a6911c617f1f554571849afbb3a2b7fc 277 PIRSF PIRSF006483 1 277 2.1E-81 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS09450 c1005aadde48d286a556cb6b93c4b7db 151 Gene3D G3DSA:3.40.630.30 1 151 1.3E-24 T 28-03-2018 A21D_RS09450 c1005aadde48d286a556cb6b93c4b7db 151 SUPERFAMILY SSF55729 1 149 7.85E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS09450 c1005aadde48d286a556cb6b93c4b7db 151 Pfam PF00583 Acetyltransferase (GNAT) family 35 115 8.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS08460 d2ac2f9f0278f305bea0d8e9b62350ba 317 Pfam PF12679 ABC-2 family transporter protein 7 314 6.6E-21 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A21D_RS15205 437ff5f62d2cd646dc23bd88cca19f34 256 SUPERFAMILY SSF51261 99 249 7.32E-16 T 28-03-2018 IPR011055 Duplicated hybrid motif A21D_RS15205 437ff5f62d2cd646dc23bd88cca19f34 256 Pfam PF01551 Peptidase family M23 155 246 1.1E-17 T 28-03-2018 IPR016047 Peptidase M23 A21D_RS15205 437ff5f62d2cd646dc23bd88cca19f34 256 Gene3D G3DSA:2.70.70.10 3 253 1.2E-18 T 28-03-2018 A21D_RS04645 904ff59728438fcb4a26294bd93723e8 210 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 10 173 1.6E-59 T 28-03-2018 IPR014202 Sporulation stage II, protein R A21D_RS04645 904ff59728438fcb4a26294bd93723e8 210 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 43 169 3.4E-46 T 28-03-2018 IPR014202 Sporulation stage II, protein R A21D_RS09105 ca1aa86c1c59d5f13ab6205d3dd9d3f6 181 Pfam PF03061 Thioesterase superfamily 32 107 6.3E-18 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A21D_RS09105 ca1aa86c1c59d5f13ab6205d3dd9d3f6 181 Gene3D G3DSA:3.10.129.10 3 163 6.9E-50 T 28-03-2018 A21D_RS09105 ca1aa86c1c59d5f13ab6205d3dd9d3f6 181 SUPERFAMILY SSF54637 12 161 2.39E-46 T 28-03-2018 IPR029069 HotDog domain A21D_RS10215 bd51b0cf8a0a68814b59c93ec7c3e0a2 234 Pfam PF02517 CAAX protease self-immunity 123 207 1.1E-17 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A21D_RS14765 3fa16e1e6f5b53d709aa4e0a35ed10f8 181 Pfam PF02674 Colicin V production protein 3 162 2.6E-36 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A21D_RS15000 93b9afe53e445eda0ce6db1559b6d8cb 276 PIRSF PIRSF006483 1 275 5.3E-68 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS15000 93b9afe53e445eda0ce6db1559b6d8cb 276 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 1.7E-51 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A21D_RS15000 93b9afe53e445eda0ce6db1559b6d8cb 276 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 270 3.6E-16 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 A21D_RS17620 20b400088075af7a134872bcde3e5008 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 287 5.3E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A21D_RS17620 20b400088075af7a134872bcde3e5008 319 Gene3D G3DSA:1.10.3470.10 4 306 1.2E-44 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A21D_RS13310 2ecb5e1433faf97aeed7441007b30a3f 192 Gene3D G3DSA:3.90.20.10 3 84 2.0E-4 T 28-03-2018 A21D_RS13310 2ecb5e1433faf97aeed7441007b30a3f 192 Pfam PF10737 Spore germination protein GerPC 24 185 3.2E-36 T 28-03-2018 IPR019673 Spore germination protein GerPC A21D_RS02805 0aab6869d6251c0de3fcfb024cd8e12b 100 Pfam PF02583 Metal-sensitive transcriptional repressor 20 96 3.1E-31 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A21D_RS02805 0aab6869d6251c0de3fcfb024cd8e12b 100 Gene3D G3DSA:1.10.287.210 9 100 0.0024 T 28-03-2018 A21D_RS02470 50a9347c1524f8ddc60ce420bec80e6f 320 Gene3D G3DSA:3.40.190.10 116 231 3.5E-14 T 28-03-2018 A21D_RS02470 50a9347c1524f8ddc60ce420bec80e6f 320 PIRSF PIRSF017082 1 319 1.6E-106 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A21D_RS02470 50a9347c1524f8ddc60ce420bec80e6f 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 316 6.9E-31 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A21D_RS02470 50a9347c1524f8ddc60ce420bec80e6f 320 SUPERFAMILY SSF53850 22 284 2.06E-10 T 28-03-2018 A21D_RS18225 e5d7d24cac272d273725276d523a5a48 294 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 294 3.3E-67 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 A21D_RS18225 e5d7d24cac272d273725276d523a5a48 294 Pfam PF03755 YicC-like family, N-terminal region 3 156 1.2E-36 T 28-03-2018 IPR013527 YicC-like, N-terminal A21D_RS18225 e5d7d24cac272d273725276d523a5a48 294 Pfam PF08340 Domain of unknown function (DUF1732) 210 294 4.7E-30 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 A21D_RS00700 132d2c79eb1726bb9ffdab283da991a1 320 Pfam PF07670 Nucleoside recognition 17 98 1.0E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS00700 132d2c79eb1726bb9ffdab283da991a1 320 Pfam PF07670 Nucleoside recognition 176 262 2.5E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS15110 ed565d7df772765faca1cb6bc6b8e626 272 Pfam PF01578 Cytochrome C assembly protein 66 268 4.4E-27 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A21D_RS09785 d4a614ffa94f751e0561b48d0df849c9 168 Pfam PF07853 Protein of unknown function (DUF1648) 28 73 1.0E-14 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 A21D_RS15075 844b96c41e3115bea00b9e07f5f0d997 325 SUPERFAMILY SSF48452 11 100 1.71E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS15075 844b96c41e3115bea00b9e07f5f0d997 325 SUPERFAMILY SSF116965 76 284 1.7E-12 T 28-03-2018 A21D_RS15075 844b96c41e3115bea00b9e07f5f0d997 325 Gene3D G3DSA:1.25.40.10 15 325 5.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A21D_RS11180 be3212489b74ecfcedb800a8eabc397b 72 ProDom PD058323 YUZF BH2251 6 71 2.0E-13 T 28-03-2018 IPR020139 Protein of unknown function DUF2642 A21D_RS11180 be3212489b74ecfcedb800a8eabc397b 72 Pfam PF10842 Protein of unknown function (DUF2642) 8 70 5.3E-30 T 28-03-2018 IPR020139 Protein of unknown function DUF2642 A21D_RS11080 d42f565daccbe06649366409ea673174 253 Pfam PF01925 Sulfite exporter TauE/SafE 10 246 1.6E-38 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A21D_RS15010 604b4d6825b0c33705c7a9c1b3cc8527 460 SUPERFAMILY SSF56300 65 323 8.41E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS15010 604b4d6825b0c33705c7a9c1b3cc8527 460 Gene3D G3DSA:3.60.21.10 49 332 1.6E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A21D_RS14650 121ca712aeb4e2511d7537faad0b38b5 285 PIRSF PIRSF012563 1 285 3.5E-90 T 28-03-2018 IPR014199 Sporulation protein YtxC A21D_RS14650 121ca712aeb4e2511d7537faad0b38b5 285 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 3 267 8.9E-66 T 28-03-2018 IPR014199 Sporulation protein YtxC A21D_RS14650 121ca712aeb4e2511d7537faad0b38b5 285 Pfam PF08812 YtxC-like family 55 266 9.6E-45 T 28-03-2018 IPR014199 Sporulation protein YtxC A21D_RS18460 8b6cb091189fcbadc50cd9bff73ce6aa 176 Pfam PF02620 Uncharacterized ACR, COG1399 57 168 9.2E-17 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A21D_RS01265 53996e07a8bfc8a9eb1cb729c8d93170 484 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 321 427 7.5E-20 T 28-03-2018 IPR025299 CstA, C-terminal domain A21D_RS01265 53996e07a8bfc8a9eb1cb729c8d93170 484 Pfam PF02554 Carbon starvation protein CstA 5 161 5.0E-33 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A21D_RS17650 8d9031dd22c4ec0f76ba45c8d9998443 72 Pfam PF14035 YlzJ-like protein 4 66 1.0E-20 T 28-03-2018 IPR025619 YlzJ-like protein A21D_RS16310 0b88578126173e849ed3d31c78445654 68 Pfam PF14004 Protein of unknown function (DUF4227) 5 68 2.6E-21 T 28-03-2018 IPR025321 Protein of unknown function DUF4227 A21D_RS05675 fd23d5415c3e56279108ba937287e457 150 Pfam PF06103 Bacterial protein of unknown function (DUF948) 9 95 1.8E-17 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 A21D_RS16820 4934bb79ed717f0f6c8e02b62e7747cf 168 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 78 165 1.7E-26 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 A21D_RS13840 03261879464526ea055dc0b9eb499843 271 Pfam PF01925 Sulfite exporter TauE/SafE 7 265 2.7E-56 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A21D_RS02755 7d18285601a2d1a224d27ac285cfc9c3 262 Pfam PF01925 Sulfite exporter TauE/SafE 8 251 1.5E-33 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A21D_RS02465 1575acbd02312dd38d7eb7b36d6af8c0 149 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 11 143 1.5E-18 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 A21D_RS10350 48b0f8dd3752e4f0ae9df565ae2a42cd 294 Pfam PF13614 AAA domain 5 196 5.0E-34 T 28-03-2018 IPR025669 AAA domain A21D_RS10350 48b0f8dd3752e4f0ae9df565ae2a42cd 294 Gene3D G3DSA:3.40.50.300 1 274 5.6E-33 T 28-03-2018 A21D_RS10350 48b0f8dd3752e4f0ae9df565ae2a42cd 294 SUPERFAMILY SSF52540 5 222 5.94E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A21D_RS14940 39e2e11e5ef1188117aacae9f55476fa 430 Pfam PF03916 Polysulphide reductase, NrfD 56 374 2.1E-48 T 28-03-2018 IPR005614 NrfD family A21D_RS14940 39e2e11e5ef1188117aacae9f55476fa 430 Gene3D G3DSA:1.20.1630.10 46 378 3.6E-59 T 28-03-2018 A21D_RS19060 687137d482c306bb7b4c72c116861ff0 96 TIGRFAM TIGR04197 T7SS_SACOL2603: type VII secretion effector, TIGR04197 family 8 88 8.1E-12 T 28-03-2018 IPR021477 Type VII secretion effector, SACOL2603 family A21D_RS19060 687137d482c306bb7b4c72c116861ff0 96 Pfam PF17279 Family of unknown function (DUF5344) 5 88 1.3E-6 T 28-03-2018 A21D_RS02645 f9a687de85ee5de737d1f83350935de7 283 SUPERFAMILY SSF51735 1 231 1.03E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain A21D_RS02645 f9a687de85ee5de737d1f83350935de7 283 Pfam PF01370 NAD dependent epimerase/dehydratase family 43 197 2.8E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A21D_RS02645 f9a687de85ee5de737d1f83350935de7 283 Gene3D G3DSA:3.40.50.720 30 276 8.4E-23 T 28-03-2018 A21D_RS18060 f8c3d0ec27716d2413ac49949c25347c 92 Pfam PF00886 Ribosomal protein S16 9 67 3.4E-25 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18060 f8c3d0ec27716d2413ac49949c25347c 92 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 3.8E-35 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18060 f8c3d0ec27716d2413ac49949c25347c 92 Gene3D G3DSA:3.30.1320.10 2 85 1.5E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18060 f8c3d0ec27716d2413ac49949c25347c 92 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.371 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS18060 f8c3d0ec27716d2413ac49949c25347c 92 SUPERFAMILY SSF54565 2 86 4.97E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A21D_RS05555 c8eab460c792829b6f40d764f231556f 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 105 5.1E-24 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD A21D_RS14330 d3ebda63a3cf7d09f94db35e5427cf4c 139 Gene3D G3DSA:1.20.120.20 6 138 2.6E-6 T 28-03-2018 A21D_RS14330 d3ebda63a3cf7d09f94db35e5427cf4c 139 Pfam PF12732 YtxH-like protein 13 86 3.5E-18 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH A21D_RS17765 09840fb7573cd750dbd07ca1e8bda0e0 266 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 224 250 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A21D_RS17765 09840fb7573cd750dbd07ca1e8bda0e0 266 Pfam PF01148 Cytidylyltransferase family 2 262 2.6E-69 T 28-03-2018 A21D_RS19540 a08738fa63ce78140576db765b9be8c1 327 Gene3D G3DSA:3.40.50.970 1 327 2.6E-81 T 28-03-2018 A21D_RS19540 a08738fa63ce78140576db765b9be8c1 327 Pfam PF00676 Dehydrogenase E1 component 18 313 1.5E-85 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A21D_RS19540 a08738fa63ce78140576db765b9be8c1 327 SUPERFAMILY SSF52518 4 325 8.04E-96 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS01535 895ee36965a58fd6b7a1659f5a3d5f0f 230 Pfam PF04402 Protein of unknown function (DUF541) 29 222 3.8E-39 T 28-03-2018 IPR007497 Protein of unknown function DUF541 A21D_RS16210 d97f0fbe2343c4284ca12998a5a1473e 143 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 6 140 9.7E-62 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A21D_RS16210 d97f0fbe2343c4284ca12998a5a1473e 143 Pfam PF06491 Disulphide isomerase 6 140 3.6E-61 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A21D_RS16195 f1af128439579c12c5d99460b1fa3a9a 330 Pfam PF00676 Dehydrogenase E1 component 20 320 2.2E-102 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A21D_RS16195 f1af128439579c12c5d99460b1fa3a9a 330 SUPERFAMILY SSF52518 5 330 2.75E-100 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A21D_RS16195 f1af128439579c12c5d99460b1fa3a9a 330 Gene3D G3DSA:3.40.50.970 3 330 2.6E-84 T 28-03-2018 A21D_RS16415 a9b4ccf3deac38f506780a1241e50b58 176 Pfam PF07670 Nucleoside recognition 46 146 5.3E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS12855 81da278ed0e8f82b2989bfc7e7f516d6 395 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 394 1.2E-56 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A21D_RS12855 81da278ed0e8f82b2989bfc7e7f516d6 395 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 2.3E-18 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A21D_RS03675 731c4833ca0f1fcc41ff923d0239beb3 93 ProDom PD063106 YXIC 1 89 0.001 T 28-03-2018 IPR020315 Uncharacterised protein family YxiC A21D_RS03675 731c4833ca0f1fcc41ff923d0239beb3 93 Pfam PF17279 Family of unknown function (DUF5344) 2 88 3.7E-16 T 28-03-2018 A21D_RS02815 7d3cca58b92fc6e7053b33dd67d9c4b8 189 PIRSF PIRSF016661 1 181 1.4E-47 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS02815 7d3cca58b92fc6e7053b33dd67d9c4b8 189 Pfam PF02632 BioY family 33 173 1.3E-34 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A21D_RS17145 2b4925985fdaa9f6a3c8a0ebf355674f 234 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 7.5E-57 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A21D_RS19430 b437112741f3ff60d5da56e3247de3b3 452 Pfam PF03611 PTS system sugar-specific permease component 10 407 9.1E-145 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 Gene3D G3DSA:1.10.3860.10 1 403 6.7E-92 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 SUPERFAMILY SSF118215 11 396 4.32E-90 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 PRINTS PR00173 Glutamate-aspartate symporter signature 288 314 6.5E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 6.5E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 PRINTS PR00173 Glutamate-aspartate symporter signature 139 161 6.5E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 PRINTS PR00173 Glutamate-aspartate symporter signature 351 371 6.5E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 PRINTS PR00173 Glutamate-aspartate symporter signature 186 205 6.5E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS18865 40cea7c646c617193cf8a9a95d2ef046 410 Pfam PF00375 Sodium:dicarboxylate symporter family 13 396 1.0E-100 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A21D_RS12015 2d634f3c91f27e3994e4d39e57b42c51 449 Pfam PF03611 PTS system sugar-specific permease component 7 387 1.5E-77 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS12015 2d634f3c91f27e3994e4d39e57b42c51 449 PIRSF PIRSF006304 1 449 3.0E-160 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 A21D_RS10565 138237a8bb33fc53d60ec757d391070c 346 Pfam PF11553 Protein of unknown function (DUF3231) 183 341 4.1E-40 T 28-03-2018 IPR021617 Protein of unknown function DUF3231 A21D_RS10565 138237a8bb33fc53d60ec757d391070c 346 Pfam PF11553 Protein of unknown function (DUF3231) 14 171 8.3E-49 T 28-03-2018 IPR021617 Protein of unknown function DUF3231 A21D_RS10565 138237a8bb33fc53d60ec757d391070c 346 Gene3D G3DSA:1.20.1260.10 183 328 1.6E-11 T 28-03-2018 IPR012347 Ferritin-related A21D_RS10565 138237a8bb33fc53d60ec757d391070c 346 Gene3D G3DSA:1.20.1260.10 6 158 2.8E-16 T 28-03-2018 IPR012347 Ferritin-related A21D_RS15190 50a12d0d5d7526fef99cbb3104400392 179 Pfam PF04093 rod shape-determining protein MreD 3 163 1.3E-18 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A21D_RS15190 50a12d0d5d7526fef99cbb3104400392 179 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 160 4.5E-22 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A21D_RS12285 0cc2900488af4ddf87cb602b1005f93b 431 Pfam PF03611 PTS system sugar-specific permease component 10 401 3.8E-122 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 A21D_RS08190 4872e32601bc1c82015f30353c547804 268 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 3 268 1.1E-91 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 A21D_RS12720 def17e089f9a32b492661758d9d0d49d 430 TIGRFAM TIGR03173 pbuX: xanthine permease 6 412 5.8E-165 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 A21D_RS12720 def17e089f9a32b492661758d9d0d49d 430 Pfam PF00860 Permease family 4 380 3.3E-118 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS12720 def17e089f9a32b492661758d9d0d49d 430 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 327 347 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A21D_RS12720 def17e089f9a32b492661758d9d0d49d 430 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 3 409 1.2E-137 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A21D_RS13805 15518a24033f8307e918aea4db8ba0b9 518 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 18 508 6.4E-116 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A21D_RS18630 0688571f0a4b1c04d568e0add562ad0b 35 Pfam PF13790 SR1 protein 1 33 2.0E-15 T 28-03-2018 IPR025236 SR1 protein A21D_RS17320 0ca99ffd75170ba3e35d2d2fc5000c3d 556 Pfam PF03354 Phage Terminase 65 539 8.9E-36 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type A21D_RS11660 d3160a9e81e5fe9f2082f2d69924f1f6 364 Pfam PF07853 Protein of unknown function (DUF1648) 145 193 1.3E-10 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 A21D_RS11660 d3160a9e81e5fe9f2082f2d69924f1f6 364 PIRSF PIRSF032908 1 364 1.1E-74 T 28-03-2018 IPR014574 Uncharacterised conserved protein UCP032908 A21D_RS09350 93d145bb6a6f18884235a6d406be23a2 142 Pfam PF13673 Acetyltransferase (GNAT) domain 26 126 1.8E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A21D_RS09350 93d145bb6a6f18884235a6d406be23a2 142 Gene3D G3DSA:3.40.630.30 1 142 1.8E-20 T 28-03-2018 A21D_RS09350 93d145bb6a6f18884235a6d406be23a2 142 SUPERFAMILY SSF55729 1 140 2.34E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A21D_RS00460 9433ebe70947917bd629c0b6fa64e907 248 Gene3D G3DSA:3.40.50.1820 1 246 4.6E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS00460 9433ebe70947917bd629c0b6fa64e907 248 SUPERFAMILY SSF53474 15 244 1.26E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS00460 9433ebe70947917bd629c0b6fa64e907 248 Pfam PF12146 Serine aminopeptidase, S33 17 225 2.8E-18 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A21D_RS00460 9433ebe70947917bd629c0b6fa64e907 248 PIRSF PIRSF017388 1 246 8.0E-88 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 A21D_RS08985 0222a5c102e171399c2ff47633f87d59 666 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 132 578 7.6E-86 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A21D_RS08985 0222a5c102e171399c2ff47633f87d59 666 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 35 652 5.0E-228 T 28-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein A21D_RS09590 ab8d450fb8640cbbf90efec04540f6cb 61 Gene3D G3DSA:1.20.1260.10 1 61 6.2E-7 T 28-03-2018 IPR012347 Ferritin-related A21D_RS09860 912accc3d49e5ed08432bfdc32ccc186 270 Pfam PF04018 Domain of unknown function (DUF368) 12 243 3.2E-54 T 28-03-2018 IPR007163 Protein of unknown function DUF368 A21D_RS03390 b32cb845f6e716d9aea2533fa3a3de32 114 Pfam PF13157 Protein of unknown function (DUF3992) 19 106 1.2E-12 T 28-03-2018 IPR025055 Protein of unknown function DUF3992 A21D_RS08785 a8c359efa6ee4ff5f8059bd3c5a84c28 130 Pfam PF04134 Protein of unknown function, DUF393 6 114 9.6E-35 T 28-03-2018 IPR007263 Protein of unknown function DUF393 A21D_RS17260 2589b49370f3e4b7efa41698ad26c05d 478 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 6 130 4.0E-20 T 28-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal A21D_RS17260 2589b49370f3e4b7efa41698ad26c05d 478 Pfam PF05709 Phage tail protein 24 477 4.1E-38 T 28-03-2018 IPR008841 Siphovirus-type tail component A21D_RS04160 62f2c75b9526798ac8d68a13727f7d50 207 Gene3D G3DSA:3.90.79.10 1 205 8.7E-37 T 28-03-2018 A21D_RS04160 62f2c75b9526798ac8d68a13727f7d50 207 SUPERFAMILY SSF55811 16 196 2.36E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A21D_RS04160 62f2c75b9526798ac8d68a13727f7d50 207 Pfam PF00293 NUDIX domain 35 146 3.5E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A21D_RS08325 57d2fd552b99fe2cd8c83c1046892c1d 191 Pfam PF14005 YpjP-like protein 64 189 2.0E-49 T 28-03-2018 IPR025616 YpjP-like protein A21D_RS13430 4ca70d402398cc8c296b9bcc22a35bde 251 Pfam PF12227 Protein of unknown function (DUF3603) 35 246 1.2E-100 T 28-03-2018 IPR020909 UPF0736 A21D_RS13590 d82164fc2d408dcfb07f1a81aeb47a1e 352 Pfam PF03547 Membrane transport protein 17 159 1.7E-21 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A21D_RS17285 1bfbdf731a04b98fc66b08972e5b9144 127 Pfam PF11367 Protein of unknown function (DUF3168) 7 96 2.9E-6 T 28-03-2018 IPR021508 Tail completion protein A21D_RS12990 deb7008c2d46b9b55f168152b6531da0 303 Pfam PF00882 Zinc dependent phospholipase C 6 147 2.5E-9 T 28-03-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 A21D_RS05235 ec251c0739316ef18fb449021ae2c0c1 70 Pfam PF11193 Protein of unknown function (DUF2812) 13 62 6.6E-6 T 28-03-2018 IPR021359 Protein of unknown function DUF2812 A21D_RS02735 2298e40725773a7aac94364db8f4915e 205 Pfam PF04854 Protein of unknown function, DUF624 18 93 6.4E-29 T 28-03-2018 IPR006938 Protein of unknown function DUF624 A21D_RS18475 b7e69913068ef6f90606f9d5f44ac80c 391 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 3 351 2.5E-118 T 28-03-2018 IPR014226 Sporulation integral membrane protein YlbJ A21D_RS18475 b7e69913068ef6f90606f9d5f44ac80c 391 Pfam PF07670 Nucleoside recognition 32 124 1.1E-8 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A21D_RS14565 7ec5e12cddccd5d5e5a7489cd4375a4f 129 Pfam PF04186 FxsA cytoplasmic membrane protein 7 113 2.1E-34 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A21D_RS08835 2a5073a9447968c9572bc042aee4c22a 204 Pfam PF04892 VanZ like family 67 195 3.2E-20 T 28-03-2018 IPR006976 VanZ-like A21D_RS15985 996712eea0d4aa18badddabbf9156dbc 63 Pfam PF14038 YqzE-like protein 3 54 1.6E-21 T 28-03-2018 IPR025622 YqzE-like protein A21D_RS05955 199949679149d8835ccd3a300c5a0db6 183 Pfam PF11667 Putative zincin peptidase 67 167 2.2E-29 T 28-03-2018 IPR021683 Putative zincin peptidase A21D_RS09595 69bbf9d37beaa6b91ac46b2302646791 84 Gene3D G3DSA:1.20.1260.10 1 61 1.4E-5 T 28-03-2018 IPR012347 Ferritin-related A21D_RS09595 69bbf9d37beaa6b91ac46b2302646791 84 Pfam PF07875 Coat F domain 3 64 7.5E-18 T 28-03-2018 IPR012851 Spore coat protein CotF-like A21D_RS07435 f93a1dfc7804946daf98a5c8ed62540e 115 Pfam PF00893 Small Multidrug Resistance protein 4 92 6.7E-15 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A21D_RS07435 f93a1dfc7804946daf98a5c8ed62540e 115 SUPERFAMILY SSF103481 7 103 1.44E-10 T 28-03-2018 A21D_RS01040 13300613c5f6be70ecdb10dff34eaccd 80 Gene3D G3DSA:1.20.5.340 6 67 5.5E-6 T 28-03-2018 A21D_RS01480 3dfdfe26ec05bf848b43ac94a1a1808d 255 Gene3D G3DSA:1.20.1270.30 12 90 1.0E-4 T 28-03-2018 A21D_RS01480 3dfdfe26ec05bf848b43ac94a1a1808d 255 Gene3D G3DSA:1.20.1270.30 91 136 0.0046 T 28-03-2018 A21D_RS01480 3dfdfe26ec05bf848b43ac94a1a1808d 255 Gene3D G3DSA:1.20.1270.30 159 208 0.32 T 28-03-2018 A21D_RS18930 b254c566b16f1404aa37fc2ef89ff5b6 428 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 12 414 1.0E-125 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A21D_RS18930 b254c566b16f1404aa37fc2ef89ff5b6 428 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A21D_RS18930 b254c566b16f1404aa37fc2ef89ff5b6 428 Pfam PF00860 Permease family 19 393 7.7E-102 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS04920 1560678a8f1ef2c7fbc5fc16d12f4cc8 350 Pfam PF12698 ABC-2 family transporter protein 18 341 1.5E-32 T 28-03-2018 A21D_RS00955 e91bff910e1e01c2f095663a422f6f5c 118 Pfam PF05610 Protein of unknown function (DUF779) 14 107 5.3E-49 T 28-03-2018 IPR008497 Protein of unknown function DUF779 A21D_RS00955 e91bff910e1e01c2f095663a422f6f5c 118 PIRSF PIRSF009151 1 118 3.9E-61 T 28-03-2018 IPR008497 Protein of unknown function DUF779 A21D_RS18780 faa0af9ec16e7e53da048f2c4f44f101 59 SUPERFAMILY SSF140500 4 49 4.19E-13 T 28-03-2018 A21D_RS18780 faa0af9ec16e7e53da048f2c4f44f101 59 Pfam PF09388 Spo0E like sporulation regulatory protein 7 46 5.9E-14 T 28-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A21D_RS04165 b0732eb3e6a45c96e9a20c9f5f4fa73b 69 Pfam PF12841 YvrJ protein family 8 41 1.1E-14 T 28-03-2018 IPR024419 Protein of unknown function YvrJ A21D_RS09575 e15580ad987f5409a5b772da73d5151b 259 Pfam PF08241 Methyltransferase domain 63 158 1.5E-14 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A21D_RS09575 e15580ad987f5409a5b772da73d5151b 259 SUPERFAMILY SSF53335 57 252 1.39E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A21D_RS09575 e15580ad987f5409a5b772da73d5151b 259 Gene3D G3DSA:3.40.50.150 9 240 2.9E-16 T 28-03-2018 A21D_RS02265 0b626c43477fd2b38ad62a87a29cc538 382 PIRSF PIRSF016719 1 382 1.9E-150 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 A21D_RS02265 0b626c43477fd2b38ad62a87a29cc538 382 Pfam PF07075 Protein of unknown function (DUF1343) 21 381 6.8E-139 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 A21D_RS18500 1f7d5f5e64ab0cfb398a24457f27c0e1 77 Pfam PF14003 YlbE-like protein 13 70 1.5E-23 T 28-03-2018 IPR025613 YlbE-like protein A21D_RS08515 37b37d710ee1a5c2a33840dd6c64cb95 458 Pfam PF10011 Predicted membrane protein (DUF2254) 28 391 1.1E-85 T 28-03-2018 IPR018723 Protein of unknown function DUF2254, membrane A21D_RS05455 c0dc13fe316e79ec4fa83f5fa84aa834 110 Pfam PF05709 Phage tail protein 9 110 5.5E-15 T 28-03-2018 IPR008841 Siphovirus-type tail component A21D_RS05315 5a81b0bbb7e8b46b9a877639231b4b2f 210 Pfam PF13490 Putative zinc-finger 3 38 1.3E-8 T 28-03-2018 IPR027383 Putative zinc-finger A21D_RS08095 dd80b1b6405dcb762d54347579e06ffc 252 Pfam PF08892 YqcI/YcgG family 33 240 1.1E-77 T 28-03-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG A21D_RS01715 92bf3c87e6a8487b71474314b20325f4 73 Pfam PF11195 Protein of unknown function (DUF2829) 2 72 1.2E-24 T 28-03-2018 IPR021361 Protein of unknown function DUF2829 A21D_RS06530 14c373a054341edf85c199ae7a0144f5 232 Pfam PF02308 MgtC family 20 150 1.4E-37 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A21D_RS06530 14c373a054341edf85c199ae7a0144f5 232 PRINTS PR01837 MgtC/SapB protein signature 42 60 1.9E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A21D_RS06530 14c373a054341edf85c199ae7a0144f5 232 PRINTS PR01837 MgtC/SapB protein signature 104 128 1.9E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A21D_RS06530 14c373a054341edf85c199ae7a0144f5 232 PRINTS PR01837 MgtC/SapB protein signature 23 42 1.9E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A21D_RS06530 14c373a054341edf85c199ae7a0144f5 232 PRINTS PR01837 MgtC/SapB protein signature 77 99 1.9E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A21D_RS19190 9da1721994dbf29c0dbf157d68019c7b 415 Pfam PF04143 Sulphur transport 66 395 4.4E-75 T 28-03-2018 IPR007272 Sulphur transport domain A21D_RS12525 a4208715a25272df211acc00d986c25a 46 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 11 45 3.8E-15 T 28-03-2018 IPR017526 Small acid-soluble spore protein, SspL A21D_RS09840 70c1267bccd00ed3566fcc5f0950c1fb 52 Pfam PF14152 YfhE-like protein 10 36 2.7E-10 T 28-03-2018 IPR025437 YfhE-like protein A21D_RS14170 d7ce84911c684c793a2eb7926de1ba07 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 1.5E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS14170 d7ce84911c684c793a2eb7926de1ba07 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 9.7E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A21D_RS14170 d7ce84911c684c793a2eb7926de1ba07 170 Gene3D G3DSA:2.160.10.10 1 170 2.9E-41 T 28-03-2018 A21D_RS14170 d7ce84911c684c793a2eb7926de1ba07 170 SUPERFAMILY SSF51161 3 167 2.77E-46 T 28-03-2018 IPR011004 Trimeric LpxA-like A21D_RS11100 4a17d5cf71d2d1a1f06bb999b56ecfe9 158 Pfam PF11188 Protein of unknown function (DUF2975) 32 158 1.3E-31 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 A21D_RS16085 df2f3daebd52f86e503338f0e0ed949e 193 Pfam PF12685 SpoIIIAH-like protein 5 179 3.7E-25 T 28-03-2018 IPR024232 Stage III sporulation protein AH-like A21D_RS12770 b111e7eba98eafa33b89a5977b256aad 192 Pfam PF12698 ABC-2 family transporter protein 6 182 6.3E-10 T 28-03-2018 A21D_RS13245 9eb6c2d441485d642450e312d093d7da 42 Pfam PF14149 YhfH-like protein 1 37 5.0E-18 T 28-03-2018 IPR025432 YhfH-like protein A21D_RS15100 729e0089dfe328a5b34992f5859467cb 160 ProDom PD104119 YSXD OB2071 ORFY 1 160 2.0E-36 T 28-03-2018 A21D_RS10340 4436a5227c781db9a3d31ee211e6fb50 66 Pfam PF17356 Phage-like element PBSX protein XtrA 2 66 5.7E-27 T 28-03-2018 IPR035530 Phage-like element PBSX protein XtrA A21D_RS18090 ecc63d91e952d6b46fb57ed08301e757 73 Pfam PF06569 Protein of unknown function (DUF1128) 3 73 1.4E-23 T 28-03-2018 IPR009507 Protein of unknown function UPF0435 A21D_RS16675 7c335235f0ec0e3ea0da7568c77fb467 196 Pfam PF07187 Protein of unknown function (DUF1405) 22 178 4.4E-57 T 28-03-2018 IPR009845 Protein of unknown function DUF1405 A21D_RS05105 14317dbce7a95b01af74e7a6f1d2b136 126 Gene3D G3DSA:3.40.50.450 1 124 1.3E-11 T 28-03-2018 A21D_RS05105 14317dbce7a95b01af74e7a6f1d2b136 126 SUPERFAMILY SSF52309 2 92 1.07E-6 T 28-03-2018 A21D_RS05105 14317dbce7a95b01af74e7a6f1d2b136 126 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 95 1.4E-6 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 A21D_RS10235 7aeebacc737f494084c9607b0463c3d1 175 Pfam PF06114 IrrE N-terminal-like domain 78 154 1.4E-8 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A21D_RS00965 9fb89a226d7582de653b854a3c25f8f8 60 Pfam PF14169 Cold-inducible protein YdjO 1 59 3.4E-29 T 28-03-2018 IPR025916 Cold-inducible protein YdjO A21D_RS08980 94ae0a00155f1b591954eb32f30d0efb 178 Pfam PF08905 Domain of unknown function (DUF1850) 59 141 1.1E-18 T 28-03-2018 IPR015001 Protein of unknown function DUF1850 A21D_RS01485 1c6262aecfff647a7eb8db5618453c2c 136 Gene3D G3DSA:1.10.287.990 23 72 7.7E-4 T 28-03-2018 A21D_RS05305 ae1ed0c7dc93c9e58160ab306d98d987 413 Pfam PF07949 YbbR-like protein 56 134 5.5E-7 T 28-03-2018 IPR012505 YbbR-like A21D_RS05305 ae1ed0c7dc93c9e58160ab306d98d987 413 Pfam PF07949 YbbR-like protein 144 227 8.2E-14 T 28-03-2018 IPR012505 YbbR-like A21D_RS05305 ae1ed0c7dc93c9e58160ab306d98d987 413 Pfam PF07949 YbbR-like protein 328 396 1.1E-5 T 28-03-2018 IPR012505 YbbR-like A21D_RS05305 ae1ed0c7dc93c9e58160ab306d98d987 413 Pfam PF07949 YbbR-like protein 238 317 1.9E-13 T 28-03-2018 IPR012505 YbbR-like A21D_RS17275 7cb73ba3f548131e965bb8ab933038b7 187 ProDom PD012849 LATE FIBER GP8.5 HEAD 1 136 1.0E-4 T 28-03-2018 A21D_RS04095 9c44f3fcc2771fca466dd28bd9f77d4d 273 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 17 273 7.8E-103 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 A21D_RS05480 112be6e0a667240e76fc742eaca7fba7 121 Pfam PF12363 Phage tail assembly chaperone protein, TAC 2 113 2.2E-35 T 28-03-2018 IPR024410 Phage tail assembly chaperone protein, TAC A21D_RS08690 22eff1c8038bebef007e0c3d076489b8 229 Pfam PF04172 LrgB-like family 14 226 2.4E-67 T 28-03-2018 IPR007300 CidB/LrgB family A21D_RS03935 bd61e4fca89bb664a95c0d94e96bccd8 186 Pfam PF08006 Protein of unknown function (DUF1700) 2 181 3.9E-54 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 A21D_RS00080 dc4403e4868a9744164ed64243dc0854 174 Gene3D G3DSA:1.10.10.10 6 162 6.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A21D_RS06175 3a03e0f89ef02b132ac58c3be8fd4874 418 Pfam PF01764 Lipase (class 3) 62 213 7.3E-8 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A21D_RS06175 3a03e0f89ef02b132ac58c3be8fd4874 418 SUPERFAMILY SSF53474 129 231 5.41E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS06175 3a03e0f89ef02b132ac58c3be8fd4874 418 SUPERFAMILY SSF53474 9 99 5.41E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS06175 3a03e0f89ef02b132ac58c3be8fd4874 418 Gene3D G3DSA:3.40.50.1820 4 307 1.1E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A21D_RS10845 2778ebbe14da435f177a506bb405e0de 506 Pfam PF03806 AbgT putative transporter family 11 506 2.7E-206 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 A21D_RS13035 1ddb61d392eb79003bfb0c2dc818efa9 107 Gene3D G3DSA:1.20.1250.20 7 106 8.5E-4 T 28-03-2018 A21D_RS07210 be313b6976b694f156f7d242042b7678 99 Pfam PF04025 Domain of unknown function (DUF370) 2 74 7.0E-13 T 28-03-2018 IPR007169 Uncharacterised protein family UPF0296 A21D_RS04195 4d90e4a42b43efda1f16414e183df809 268 Pfam PF01061 ABC-2 type transporter 18 225 2.1E-21 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A21D_RS00885 26ba6b48a1392a57655fde1f4501b03e 65 Gene3D G3DSA:3.30.1050.10 1 65 8.0E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A21D_RS10480 ad9e852f5e56080fa727e1932e3c5fd6 195 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 3 143 3.0E-25 T 28-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 A21D_RS00415 b773af3691e1d467b4f6f6de14909982 142 Pfam PF14179 YppG-like protein 76 139 8.2E-9 T 28-03-2018 IPR025555 YppG-like protein A21D_RS18530 22ea4d029d63f12ac4bf1315302235ce 301 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 28 283 2.0E-56 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A21D_RS18530 22ea4d029d63f12ac4bf1315302235ce 301 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 5 286 4.1E-126 T 28-03-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG A21D_RS04230 15e5579c8735be3ea9500c75ce1fd2d4 684 Pfam PF04230 Polysaccharide pyruvyl transferase 19 345 2.1E-29 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase A21D_RS13400 78a3069b2e0c1f6812d49983bc305bc1 57 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 1.5E-16 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 A21D_RS06855 c743faea25a45758fb2333ff84f92415 144 Gene3D G3DSA:1.20.120.490 26 143 3.1E-33 T 28-03-2018 IPR024042 Hypothetical protein TM1646-like domain A21D_RS06855 c743faea25a45758fb2333ff84f92415 144 Pfam PF03885 Protein of unknown function (DUF327) 17 143 2.7E-35 T 28-03-2018 IPR005585 Protein of unknown function DUF327 A21D_RS06855 c743faea25a45758fb2333ff84f92415 144 SUPERFAMILY SSF158397 26 144 4.05E-31 T 28-03-2018 A21D_RS00360 1df1334c64f81b285a9002fd317ae0a4 344 Pfam PF06081 Aromatic acid exporter family member 1 6 144 1.9E-37 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 A21D_RS05505 cdbc681e42e13cf33d65ab5be4085f9d 152 Pfam PF06114 IrrE N-terminal-like domain 48 141 1.0E-14 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A21D_RS03305 651c0dbae575f142a48cc00d608aca93 112 Pfam PF13799 Domain of unknown function (DUF4183) 32 106 2.4E-19 T 28-03-2018 IPR025237 Domain of unknown function DUF4183 A21D_RS10560 f0c260038a650ba55cece309306d63a6 344 Pfam PF04235 Protein of unknown function (DUF418) 234 338 1.0E-25 T 28-03-2018 IPR007349 Domain of unknown function DUF418 A21D_RS05190 a043dd8f4c8e8a96f037bcd44ce3666a 105 Pfam PF12647 RNHCP domain 8 91 4.9E-32 T 28-03-2018 IPR024439 RNHCP domain A21D_RS14690 297cc89f726734935b02ceb00beda3ab 194 Pfam PF09335 SNARE associated Golgi protein 39 149 6.3E-13 T 28-03-2018 IPR032816 SNARE associated Golgi protein A21D_RS08105 fee098aecc38f11297589c1727a2b598 128 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 4 121 3.3E-22 T 28-03-2018 IPR030910 SLAP domain, Bacillus-type A21D_RS09510 7ca97f6c08e0743e0db0ac211781d630 260 Gene3D G3DSA:1.20.120.20 25 260 0.0015 T 28-03-2018 A21D_RS05760 787ea908932e4ea693f72ce1715c95af 156 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 9 155 1.4E-34 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 A21D_RS04170 231d60ae4d673bf70d9cd63172dd7b95 71 Pfam PF11148 Protein of unknown function (DUF2922) 2 68 2.6E-26 T 28-03-2018 IPR021321 Protein of unknown function DUF2922 A21D_RS04840 15c0463c39252323e742d99b531de171 122 Pfam PF04241 Protein of unknown function (DUF423) 18 104 6.4E-30 T 28-03-2018 IPR006696 Protein of unknown function DUF423 A21D_RS13325 3459afa5999b2d20467b3715919f4848 391 Pfam PF04235 Protein of unknown function (DUF418) 231 385 7.0E-49 T 28-03-2018 IPR007349 Domain of unknown function DUF418 A21D_RS14495 974a54d0a8b41d27f8cee61119b1dfb7 98 Pfam PF14007 YtpI-like protein 7 90 2.1E-23 T 28-03-2018 IPR025618 YtpI-like protein A21D_RS02160 e799af9138896db9182e4105507e4d5c 103 Gene3D G3DSA:1.10.287.1060 5 99 4.5E-4 T 28-03-2018 A21D_RS15470 e93b0907b24cd6454cb89c7ed32fe1cb 75 Pfam PF14143 YrhC-like protein 5 74 1.1E-13 T 28-03-2018 IPR025418 YrhC-like protein A21D_RS05385 02cd925d8526f5bd867cf70377f807ba 273 Pfam PF10978 Protein of unknown function (DUF2785) 83 249 1.9E-40 T 28-03-2018 IPR021247 Protein of unknown function DUF2785 A21D_RS10540 e1321244160b36b8117dab48f0de30be 219 Pfam PF12639 DNase/tRNase domain of colicin-like bacteriocin 90 194 1.4E-19 T 28-03-2018 A21D_RS08650 6a7e5b52c4055a678a1cf6d477711632 244 Pfam PF08889 WbqC-like protein family 7 222 5.5E-75 T 28-03-2018 IPR014985 WbqC-like protein family A21D_RS09155 6373c255f5c14207f952aa498ad9cece 360 Pfam PF01594 AI-2E family transporter 20 342 9.4E-70 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A21D_RS00075 8accd99b76f9079f0211164ff30d9a51 89 Pfam PF13031 Protein of unknown function (DUF3892) 5 87 1.0E-14 T 28-03-2018 IPR024997 Protein of unknown function DUF3892 A21D_RS00380 01125cc9cfbf781b7b64256a1a115a14 210 Pfam PF04012 PspA/IM30 family 3 204 3.5E-13 T 28-03-2018 IPR007157 PspA/IM30 A21D_RS03320 eff1517f8ab201ca8c5415dbb0b92392 450 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 11 431 1.2E-46 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A21D_RS11155 4a121c502d813c7946cfa30fcca2a2c0 262 Pfam PF04892 VanZ like family 137 245 9.6E-16 T 28-03-2018 IPR006976 VanZ-like A21D_RS15310 8b4e7c3bd10b0db6e579e90cebfae3af 99 Pfam PF13797 Post-transcriptional regulator 8 87 4.2E-30 T 28-03-2018 IPR025716 Post-transcriptional regulator A21D_RS13600 3e2d0b90726a0097921999d83457f6ad 351 Pfam PF03547 Membrane transport protein 165 339 2.8E-6 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A21D_RS13600 3e2d0b90726a0097921999d83457f6ad 351 Pfam PF03547 Membrane transport protein 16 162 2.6E-21 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A21D_RS00130 afad6e6f87f6e60efaf5592a8ab1add1 391 Pfam PF10926 Protein of unknown function (DUF2800) 12 378 1.9E-139 T 28-03-2018 IPR021229 Protein of unknown function DUF2800 A21D_RS03170 777687727d88b6903d0cd5cd83e943c1 150 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 149 2.3E-23 T 28-03-2018 IPR018729 Protein of unknown function DUF2269, transmembrane A21D_RS09675 10119e8c655e385a4ba626c301e270ce 261 Pfam PF02361 Cobalt transport protein 3 217 8.4E-38 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A21D_RS04865 39d5f8d07d43f243cb379d8f8d9e88e0 333 Pfam PF01757 Acyltransferase family 5 302 4.6E-15 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A21D_RS11890 3e8cb61d267cff08bf55aba875bf8281 496 Pfam PF00474 Sodium:solute symporter family 39 429 1.0E-35 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A21D_RS18915 66e2b01b84d90bc6a7014ae69d26f438 290 Pfam PF04294 VanW like protein 148 277 2.0E-49 T 28-03-2018 IPR007391 Vancomycin resistance VanW