locus-tag	class	description
BKP57_RS00005	COG3599	regulation of cell shape
BKP57_RS00030	COG3331	DNA recombination
BKP57_RS00035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_RS00035	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKP57_RS00040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKP57_RS00045	COG3935	DnaD domain protein
BKP57_RS00050	COG0017	Asparaginyl-tRNA synthetase
BKP57_RS00055	COG0436	Aminotransferase
BKP57_RS00070	COG1199	ATP-dependent helicase activity
BKP57_RS00070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKP57_RS00075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKP57_RS00075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKP57_RS00080	COG0617	tRNA 3'-terminal CCA addition
BKP57_RS00085	COG0438	transferase activity, transferring glycosyl groups
BKP57_RS00090	COG1803	Methylglyoxal synthase
BKP57_RS00095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKP57_RS00100	COG1694	Mazg nucleotide pyrophosphohydrolase
BKP57_RS00105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_RS00110	COG2738	Putative neutral zinc metallopeptidase
BKP57_RS00120	COG4347	Protein of unknown function (DUF1405)
BKP57_RS00130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKP57_RS00135	COG0723	plastoquinol--plastocyanin reductase activity
BKP57_RS00145	COG5582	Belongs to the UPF0302 family
BKP57_RS00155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKP57_RS00160	COG0287	Prephenate dehydrogenase
BKP57_RS00165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKP57_RS00170	COG4401	Chorismate mutase type I
BKP57_RS00175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKP57_RS00180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKP57_RS00185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKP57_RS00190	COG0105	UTP biosynthetic process
BKP57_RS00195	COG0142	geranyltranstransferase activity
BKP57_RS00200	COG2226	methyltransferase
BKP57_RS00205	COG0142	geranyltranstransferase activity
BKP57_RS00215	COG0776	regulation of translation
BKP57_RS00220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP57_RS00240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKP57_RS00245	COG1160	GTP binding
BKP57_RS00260	COG0539	negative regulation of cytoplasmic translation
BKP57_RS00270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKP57_RS00280	COG2959	enzyme of heme biosynthesis
BKP57_RS00285	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_RS00285	COG3773	Cell wall hydrolase
BKP57_RS00290	COG2339	peptidase activity
BKP57_RS00300	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS00305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP57_RS00310	COG4862	establishment of competence for transformation
BKP57_RS00325	COG0514	ATP-dependent DNA helicase (RecQ)
BKP57_RS00350	COG5002	protein histidine kinase activity
BKP57_RS00355	COG0745	RESPONSE REGULATOR receiver
BKP57_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP57_RS00365	COG1333	cytochrome c biogenesis protein
BKP57_RS00370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS00375	COG1187	pseudouridine synthase activity
BKP57_RS00380	COG0700	Nucleoside recognition
BKP57_RS00385	COG2715	membrane protein required for spore maturation
BKP57_RS00390	COG1686	Belongs to the peptidase S11 family
BKP57_RS00395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP57_RS00400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKP57_RS00405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKP57_RS00425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKP57_RS00435	COG0697	spore germination
BKP57_RS00455	COG2172	sigma factor antagonist activity
BKP57_RS00465	COG1686	Belongs to the peptidase S11 family
BKP57_RS00480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKP57_RS00485	COG4974	Belongs to the 'phage' integrase family
BKP57_RS00495	COG0735	belongs to the Fur family
BKP57_RS00500	COG1300	Membrane
BKP57_RS00505	COG1379	DNA repair
BKP57_RS00515	COG0667	Aldo Keto reductase
BKP57_RS00525	COG0300	oxidoreductase activity
BKP57_RS00530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS00535	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_RS00540	COG1234	tRNA 3'-trailer cleavage
BKP57_RS00545	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS00555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_RS00560	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKP57_RS00565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_RS00570	COG0346	lactoylglutathione lyase activity
BKP57_RS00575	COG4129	membrane
BKP57_RS00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_RS00590	COG0022	dehydrogenase e1 component
BKP57_RS00595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP57_RS00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP57_RS00605	COG3426	butyrate kinase activity
BKP57_RS00615	COG0280	phosphate acetyltransferase
BKP57_RS00620	COG3829	transcription factor binding
BKP57_RS00620	COG3290	protein histidine kinase activity
BKP57_RS00630	COG0527	aspartate kinase activity
BKP57_RS00635	COG0745	RESPONSE REGULATOR receiver
BKP57_RS00640	COG0750	zinc metalloprotease
BKP57_RS00645	COG0497	DNA recombination
BKP57_RS00650	COG1438	arginine binding
BKP57_RS00655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKP57_RS00665	COG0142	geranyltranstransferase activity
BKP57_RS00670	COG1722	exodeoxyribonuclease VII activity
BKP57_RS00675	COG1570	exodeoxyribonuclease VII activity
BKP57_RS00680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKP57_RS00685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP57_RS00690	COG1302	Protein conserved in bacteria
BKP57_RS00695	COG0439	Biotin carboxylase
BKP57_RS00700	COG0511	ligase activity, forming carbon-carbon bonds
BKP57_RS00740	COG3854	ATPases associated with a variety of cellular activities
BKP57_RS00745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKP57_RS00750	COG0006	proline dipeptidase activity
BKP57_RS00765	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP57_RS00770	COG1321	iron dependent repressor
BKP57_RS00775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_RS00780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP57_RS00785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP57_RS00790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKP57_RS00795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP57_RS00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP57_RS00850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS00860	COG1368	sulfuric ester hydrolase activity
BKP57_RS00865	COG1940	carbohydrate kinase activity
BKP57_RS00875	COG0697	spore germination
BKP57_RS00885	COG0457	Tetratricopeptide repeat
BKP57_RS00885	COG0705	Rhomboid family
BKP57_RS00895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKP57_RS00900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP57_RS00915	COG0704	Plays a role in the regulation of phosphate uptake
BKP57_RS00920	COG0768	penicillin binding
BKP57_RS00925	COG0477	Major facilitator Superfamily
BKP57_RS00930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP57_RS00965	COG0704	Plays a role in the regulation of phosphate uptake
BKP57_RS00970	COG1030	water channel activity
BKP57_RS00995	COG0513	Belongs to the DEAD box helicase family
BKP57_RS01000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKP57_RS01005	COG2384	SAM-dependent methyltransferase
BKP57_RS01020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKP57_RS01025	COG0358	DNA primase activity
BKP57_RS01030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKP57_RS01035	COG0517	IMP dehydrogenase activity
BKP57_RS01040	COG0751	glycine-tRNA ligase activity
BKP57_RS01045	COG0752	glycyl-tRNA synthetase alpha subunit
BKP57_RS01050	COG1381	Involved in DNA repair and RecF pathway recombination
BKP57_RS01060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKP57_RS01065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKP57_RS01070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKP57_RS01075	COG1480	7TM receptor with intracellular HD hydrolase
BKP57_RS01080	COG1702	phosphate starvation-inducible protein PhoH
BKP57_RS01100	COG4864	UPF0365 protein
BKP57_RS01105	COG1030	water channel activity
BKP57_RS01110	COG1610	YqeY-like protein
BKP57_RS01115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKP57_RS01120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKP57_RS01125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP57_RS01130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKP57_RS01135	COG2264	protein methyltransferase activity
BKP57_RS01140	COG0484	heat shock protein binding
BKP57_RS01145	COG0443	Heat shock 70 kDa protein
BKP57_RS01150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKP57_RS01155	COG1420	regulation of RNA biosynthetic process
BKP57_RS01160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKP57_RS01165	COG0481	GTPase activity
BKP57_RS01175	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS01180	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BKP57_RS01185	COG0268	Binds directly to 16S ribosomal RNA
BKP57_RS01190	COG1466	dna polymerase III delta subunit
BKP57_RS01200	COG2333	competence protein COMEC
BKP57_RS01200	COG0658	competence protein
BKP57_RS01205	COG2131	deaminase
BKP57_RS01215	COG2226	methyltransferase
BKP57_RS01220	COG0799	negative regulation of ribosome biogenesis
BKP57_RS01225	COG1713	HD superfamily hydrolase involved in NAD metabolism
BKP57_RS01230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKP57_RS01235	COG1534	Rna-binding protein
BKP57_RS01240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKP57_RS01245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP57_RS01250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BKP57_RS01260	COG2111	Na H antiporter
BKP57_RS01260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP57_RS01265	COG1006	Multisubunit Na H antiporter MnhC subunit
BKP57_RS01270	COG0651	ATP synthesis coupled electron transport
BKP57_RS01275	COG1863	multisubunit Na H antiporter MnhE subunit
BKP57_RS01280	COG2212	antiporter activity
BKP57_RS01285	COG1320	monovalent cation:proton antiporter activity
BKP57_RS01295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS01295	COG1263	PTS System
BKP57_RS01300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKP57_RS01335	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS01355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKP57_RS01365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP57_RS01370	COG0572	uridine kinase
BKP57_RS01375	COG4122	O-methyltransferase activity
BKP57_RS01380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKP57_RS01385	COG3906	Belongs to the UPF0473 family
BKP57_RS01390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKP57_RS01395	COG4472	Bacterial protein of unknown function (DUF965)
BKP57_RS01400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKP57_RS01405	COG0628	permease
BKP57_RS01415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKP57_RS01425	COG0482	sulfurtransferase activity
BKP57_RS01430	COG1104	cysteine desulfurase activity
BKP57_RS01435	COG1959	2 iron, 2 sulfur cluster binding
BKP57_RS01440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKP57_RS01455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKP57_RS01460	COG0124	histidyl-tRNA synthetase
BKP57_RS01470	COG1490	D-aminoacyl-tRNA deacylase activity
BKP57_RS01475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP57_RS01480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_RS01485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BKP57_RS01485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKP57_RS01495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP57_RS01495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP57_RS01505	COG2244	polysaccharide biosynthetic process
BKP57_RS01510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKP57_RS01520	COG1862	Preprotein translocase
BKP57_RS01525	COG0343	queuine tRNA-ribosyltransferase activity
BKP57_RS01530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKP57_RS01540	COG2255	four-way junction helicase activity
BKP57_RS01545	COG0632	four-way junction helicase activity
BKP57_RS01550	COG0217	transcriptional regulatory protein
BKP57_RS01560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKP57_RS01565	COG3344	reverse transcriptase
BKP57_RS01575	COG0077	Prephenate dehydratase
BKP57_RS01580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKP57_RS01590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKP57_RS01595	COG2868	ribosomal protein
BKP57_RS01600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKP57_RS01605	COG1994	Peptidase M50
BKP57_RS01615	COG2894	cell division
BKP57_RS01620	COG0850	regulation of cytokinetic process
BKP57_RS01635	COG1077	Cell shape determining protein MreB Mrl
BKP57_RS01645	COG2003	Belongs to the UPF0758 family
BKP57_RS01655	COG0285	dihydrofolate synthase activity
BKP57_RS01660	COG0189	ligase activity
BKP57_RS01660	COG4067	protein conserved in archaea
BKP57_RS01670	COG0525	valine-tRNA ligase activity
BKP57_RS01685	COG1388	LysM domain
BKP57_RS01685	COG1388	LysM domain
BKP57_RS01695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP57_RS01700	COG0113	porphobilinogen synthase activity
BKP57_RS01710	COG0181	hydroxymethylbilane synthase activity
BKP57_RS01715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP57_RS01720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKP57_RS01730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKP57_RS01740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKP57_RS01745	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKP57_RS01760	COG0431	NADPH-dependent FMN reductase
BKP57_RS01760	COG1053	succinate dehydrogenase
BKP57_RS01760	COG3976	FMN-binding domain protein
BKP57_RS01765	COG3976	FMN-binding domain protein
BKP57_RS01765	COG1053	succinate dehydrogenase
BKP57_RS01765	COG0431	NADPH-dependent FMN reductase
BKP57_RS01780	COG0154	amidase activity
BKP57_RS01785	COG0840	transmembrane signaling receptor activity
BKP57_RS01820	COG5298	Protein conserved in bacteria
BKP57_RS01825	COG0622	Phosphoesterase
BKP57_RS01830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKP57_RS01835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKP57_RS01840	COG5401	PFAM Sporulation and spore germination
BKP57_RS01845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKP57_RS01850	COG1846	Transcriptional regulator
BKP57_RS01870	COG0783	Belongs to the Dps family
BKP57_RS01875	COG0314	molybdopterin synthase activity
BKP57_RS01880	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKP57_RS01890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP57_RS01900	COG1664	Polymer-forming cytoskeletal
BKP57_RS01905	COG1846	Transcriptional regulator
BKP57_RS01910	COG2223	nitrite transmembrane transporter activity
BKP57_RS01920	COG1525	nuclease
BKP57_RS01935	COG2226	methyltransferase
BKP57_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_RS01955	COG2211	Major facilitator Superfamily
BKP57_RS01980	COG1725	Transcriptional regulator
BKP57_RS02005	COG1733	regulation of RNA biosynthetic process
BKP57_RS02020	COG2085	NADP oxidoreductase coenzyme F420-dependent
BKP57_RS02045	COG1131	(ABC) transporter
BKP57_RS02065	COG4584	PFAM Integrase catalytic
BKP57_RS02065	COG2390	Transcriptional regulator
BKP57_RS02070	COG1484	DNA-dependent DNA replication
BKP57_RS02135	COG1404	Belongs to the peptidase S8 family
BKP57_RS02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP57_RS02245	COG0551	DNA topoisomerase type I activity
BKP57_RS02285	COG2197	response regulator
BKP57_RS02290	COG0824	Thioesterase
BKP57_RS02295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKP57_RS02300	COG1053	succinate dehydrogenase
BKP57_RS02305	COG2009	succinate dehydrogenase
BKP57_RS02310	COG1719	4-vinyl reductase, 4VR
BKP57_RS02315	COG0322	excinuclease ABC activity
BKP57_RS02320	COG3118	belongs to the thioredoxin family
BKP57_RS02325	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKP57_RS02330	COG2086	electron transfer activity
BKP57_RS02335	COG1024	Enoyl-CoA hydratase
BKP57_RS02340	COG1309	transcriptional regulator
BKP57_RS02345	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS02350	COG3766	membrane
BKP57_RS02355	COG1193	negative regulation of DNA recombination
BKP57_RS02360	COG1796	DNA polymerase
BKP57_RS02360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKP57_RS02365	COG1286	toxin biosynthetic process
BKP57_RS02370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BKP57_RS02375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP57_RS02380	COG0072	phenylalanine-tRNA ligase activity
BKP57_RS02380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_RS02385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKP57_RS02390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP57_RS02415	COG1131	(ABC) transporter
BKP57_RS02420	COG0741	lytic transglycosylase activity
BKP57_RS02425	COG1363	Peptidase, m42
BKP57_RS02430	COG0756	dUTP diphosphatase activity
BKP57_RS02440	COG0398	Pfam SNARE associated Golgi protein
BKP57_RS02450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKP57_RS02455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKP57_RS02460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKP57_RS02475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_RS02485	COG1484	DNA-dependent DNA replication
BKP57_RS02490	COG3611	Membrane attachment protein
BKP57_RS02495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKP57_RS02505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKP57_RS02510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP57_RS02520	COG0237	dephospho-CoA kinase activity
BKP57_RS02525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKP57_RS02530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_RS02530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_RS02535	COG5002	protein histidine kinase activity
BKP57_RS02540	COG0745	RESPONSE REGULATOR receiver
BKP57_RS02550	COG0039	L-malate dehydrogenase activity
BKP57_RS02555	COG0538	isocitrate dehydrogenase activity
BKP57_RS02560	COG0372	Belongs to the citrate synthase family
BKP57_RS02565	COG0628	permease
BKP57_RS02570	COG3030	protein affecting phage T7 exclusion by the F plasmid
BKP57_RS02580	COG0205	6-phosphofructokinase activity
BKP57_RS02585	COG0825	malonyl-CoA metabolic process
BKP57_RS02590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKP57_RS02595	COG1725	Transcriptional regulator
BKP57_RS02600	COG0281	malic enzyme
BKP57_RS02605	COG0587	DNA-directed DNA polymerase activity
BKP57_RS02630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKP57_RS02640	COG4109	DRTGG domain
BKP57_RS02650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKP57_RS02655	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKP57_RS02660	COG0006	proline dipeptidase activity
BKP57_RS02665	COG0686	Belongs to the AlaDH PNT family
BKP57_RS02670	COG0589	response to stress
BKP57_RS02675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKP57_RS02680	COG0827	DNA restriction-modification system
BKP57_RS02685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKP57_RS02690	COG3874	Sporulation protein YtfJ
BKP57_RS02700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP57_RS02710	COG0301	tRNA thio-modification
BKP57_RS02715	COG1104	cysteine desulfurase activity
BKP57_RS02720	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BKP57_RS02725	COG1309	transcriptional regulator
BKP57_RS02730	COG1956	GAF domain-containing protein
BKP57_RS02735	COG2203	Gaf domain
BKP57_RS02735	COG2199	diguanylate cyclase activity
BKP57_RS02740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKP57_RS02745	COG5444	nuclease activity
BKP57_RS02755	COG5294	Protein conserved in bacteria
BKP57_RS02760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKP57_RS02765	COG3344	reverse transcriptase
BKP57_RS02770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_RS02775	COG0454	-acetyltransferase
BKP57_RS02780	COG0517	IMP dehydrogenase activity
BKP57_RS02785	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKP57_RS02805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKP57_RS02805	COG1605	Chorismate mutase
BKP57_RS02825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKP57_RS02835	COG1674	ftsk spoiiie
BKP57_RS02840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_RS02845	COG4848	Belongs to the UPF0354 family
BKP57_RS02850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS02860	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BKP57_RS02865	COG1363	Peptidase, m42
BKP57_RS02875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS02880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKP57_RS02890	COG0510	thiamine kinase activity
BKP57_RS02905	COG1187	pseudouridine synthase activity
BKP57_RS02910	COG2244	polysaccharide biosynthetic process
BKP57_RS02915	COG2081	HI0933 family
BKP57_RS02925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BKP57_RS02945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_RS02955	COG0495	leucyl-tRNA aminoacylation
BKP57_RS02960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKP57_RS02965	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS02965	COG1454	alcohol dehydrogenase
BKP57_RS02975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKP57_RS02980	COG4990	cell redox homeostasis
BKP57_RS02985	COG0367	asparagine synthase
BKP57_RS02990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKP57_RS02995	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKP57_RS03000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP57_RS03005	COG1116	anion transmembrane transporter activity
BKP57_RS03010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP57_RS03015	COG0494	nUDIX hydrolase
BKP57_RS03055	COG1505	serine-type exopeptidase activity
BKP57_RS03065	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS03070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKP57_RS03075	COG0596	Alpha beta hydrolase
BKP57_RS03080	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKP57_RS03085	COG1169	isochorismate synthase
BKP57_RS03090	COG1575	Belongs to the MenA family. Type 1 subfamily
BKP57_RS03095	COG2050	protein possibly involved in aromatic compounds catabolism
BKP57_RS03105	COG3191	aminopeptidase activity
BKP57_RS03115	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BKP57_RS03120	COG4412	M6 family metalloprotease domain protein
BKP57_RS03120	COG1404	Belongs to the peptidase S8 family
BKP57_RS03135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP57_RS03145	COG1098	S1 RNA binding domain
BKP57_RS03150	COG2155	Conserved Protein
BKP57_RS03155	COG0166	Belongs to the GPI family
BKP57_RS03165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP57_RS03170	COG2032	superoxide dismutase activity
BKP57_RS03185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS03190	COG0813	purine-nucleoside phosphorylase activity
BKP57_RS03200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BKP57_RS03205	COG3584	3D domain protein
BKP57_RS03215	COG1252	NADH dehydrogenase
BKP57_RS03220	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS03225	COG0316	Belongs to the HesB IscA family
BKP57_RS03230	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKP57_RS03235	COG4837	Protein of unknown function (DUF1462)
BKP57_RS03240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKP57_RS03245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_RS03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP57_RS03255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKP57_RS03260	COG0647	UMP catabolic process
BKP57_RS03265	COG2445	Protein of unknown function DUF86
BKP57_RS03280	COG4470	Protein conserved in bacteria
BKP57_RS03290	COG0739	heme binding
BKP57_RS03300	COG0733	neurotransmitter:sodium symporter activity
BKP57_RS03310	COG1757	Na H antiporter
BKP57_RS03320	COG0737	Belongs to the 5'-nucleotidase family
BKP57_RS03325	COG0730	response to heat
BKP57_RS03340	COG0826	peptidase U32
BKP57_RS03365	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS03370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_RS03375	COG1757	Na H antiporter
BKP57_RS03385	COG3938	Belongs to the proline racemase family
BKP57_RS03390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_RS03415	COG0006	proline dipeptidase activity
BKP57_RS03440	COG3279	Response regulator of the LytR AlgR family
BKP57_RS03445	COG2972	Histidine kinase
BKP57_RS03445	COG0745	RESPONSE REGULATOR receiver
BKP57_RS03490	COG0745	RESPONSE REGULATOR receiver
BKP57_RS03495	COG3290	protein histidine kinase activity
BKP57_RS03500	COG4565	transcriptional regulatory protein
BKP57_RS03505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_RS03515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_RS03525	COG1132	(ABC) transporter
BKP57_RS03530	COG1132	(ABC) transporter
BKP57_RS03535	COG2382	esterase
BKP57_RS03540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKP57_RS03545	COG2153	protein acetylation
BKP57_RS03550	COG2323	membrane
BKP57_RS03580	COG2239	Acts as a magnesium transporter
BKP57_RS03585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKP57_RS03590	COG0564	pseudouridine synthase activity
BKP57_RS03595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP57_RS03600	COG2357	RelA SpoT domain protein
BKP57_RS03605	COG4116	CYTH
BKP57_RS03610	COG2346	COG2346, Truncated hemoglobins
BKP57_RS03615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKP57_RS03625	COG1164	Oligoendopeptidase f
BKP57_RS03630	COG4469	Competence protein
BKP57_RS03635	COG4862	establishment of competence for transformation
BKP57_RS03640	COG1393	Belongs to the ArsC family
BKP57_RS03655	COG0456	acetyltransferase
BKP57_RS03665	COG0709	Synthesizes selenophosphate from selenide and ATP
BKP57_RS03670	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BKP57_RS03675	COG0180	Tryptophanyl-tRNA synthetase
BKP57_RS03690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKP57_RS03695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_RS03700	COG1744	ABC transporter substrate-binding protein PnrA-like
BKP57_RS03725	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP57_RS03730	COG1073	alpha beta
BKP57_RS03735	COG0561	phosphatase activity
BKP57_RS03755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_RS03760	COG1307	EDD domain protein, DegV family
BKP57_RS03775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKP57_RS03780	COG2311	Membrane
BKP57_RS03815	COG1074	ATP-dependent DNA helicase activity
BKP57_RS03820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BKP57_RS03830	COG0398	Pfam SNARE associated Golgi protein
BKP57_RS03845	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS03850	COG0095	Lipoate-protein ligase
BKP57_RS03860	COG1164	Oligoendopeptidase f
BKP57_RS03865	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKP57_RS03870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKP57_RS03875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKP57_RS03880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_RS03890	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS03890	COG3118	belongs to the thioredoxin family
BKP57_RS03895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKP57_RS03900	COG2197	response regulator
BKP57_RS03905	COG4585	Histidine kinase
BKP57_RS03915	COG2814	Major facilitator Superfamily
BKP57_RS03930	COG1473	amidohydrolase
BKP57_RS03935	COG4473	ABC transporter
BKP57_RS03940	COG1131	(ABC) transporter
BKP57_RS03945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_RS03955	COG3069	C4-dicarboxylate transmembrane transporter activity
BKP57_RS03965	COG0537	adenosine 5'-monophosphoramidase activity
BKP57_RS04000	COG1510	regulation of RNA biosynthetic process
BKP57_RS04020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP57_RS04030	COG3481	metal-dependent phosphohydrolase, HD sub domain
BKP57_RS04040	COG1510	regulation of RNA biosynthetic process
BKP57_RS04045	COG4717	serine-type aminopeptidase activity
BKP57_RS04050	COG0420	3'-5' exonuclease activity
BKP57_RS04055	COG1668	transmembrane transport
BKP57_RS04060	COG4152	abc transporter atp-binding protein
BKP57_RS04105	COG1024	Enoyl-CoA hydratase
BKP57_RS04110	COG3679	Belongs to the UPF0342 family
BKP57_RS04115	COG2508	Transcriptional regulator
BKP57_RS04120	COG3842	ATPase activity
BKP57_RS04130	COG0114	fumarate hydratase activity
BKP57_RS04140	COG2270	Major facilitator Superfamily
BKP57_RS04150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKP57_RS04160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKP57_RS04165	COG1757	Na H antiporter
BKP57_RS04170	COG0024	Methionine aminopeptidase
BKP57_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS04190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP57_RS04210	COG1191	sigma factor activity
BKP57_RS04215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_RS04220	COG1132	(ABC) transporter
BKP57_RS04225	COG1132	(ABC) transporter
BKP57_RS04245	COG1846	Transcriptional regulator
BKP57_RS04250	COG2409	Drug exporters of the RND superfamily
BKP57_RS04250	COG1033	growth of symbiont in host cell
BKP57_RS04255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP57_RS04260	COG0534	Mate efflux family protein
BKP57_RS04265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKP57_RS04270	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_RS04275	COG0567	Dehydrogenase, E1 component
BKP57_RS04305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP57_RS04315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_RS04320	COG3275	phosphorelay sensor kinase activity
BKP57_RS04325	COG3279	Response regulator of the LytR AlgR family
BKP57_RS04330	COG3162	membrane
BKP57_RS04335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_RS04340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_RS04345	COG0563	adenylate kinase activity
BKP57_RS04350	COG4946	Tricorn protease homolog
BKP57_RS04350	COG0823	Involved in the tonB-independent uptake of proteins
BKP57_RS04350	COG1506	peptidase
BKP57_RS04355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP57_RS04360	COG0505	Belongs to the CarA family
BKP57_RS04385	COG1131	(ABC) transporter
BKP57_RS04390	COG2197	response regulator
BKP57_RS04395	COG4585	Histidine kinase
BKP57_RS04415	COG2814	Major facilitator Superfamily
BKP57_RS04420	COG2814	Major facilitator Superfamily
BKP57_RS04425	COG2814	Major facilitator Superfamily
BKP57_RS04430	COG2233	PERMEase
BKP57_RS04435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_RS04450	COG0506	proline dehydrogenase activity
BKP57_RS04455	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS04470	COG0366	Alpha amylase catalytic
BKP57_RS04480	COG2190	(PTS) system
BKP57_RS04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS04480	COG1263	PTS System
BKP57_RS04490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_RS04505	COG1024	Enoyl-CoA hydratase
BKP57_RS04510	COG1024	Enoyl-CoA hydratase
BKP57_RS04515	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS04525	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS04530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKP57_RS04535	COG3290	protein histidine kinase activity
BKP57_RS04535	COG3829	transcription factor binding
BKP57_RS04545	COG2365	Tyrosine phosphatase family
BKP57_RS04550	COG1473	amidohydrolase
BKP57_RS04555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP57_RS04560	COG0583	DNA-binding transcription factor activity
BKP57_RS04565	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS04570	COG2070	2-Nitropropane dioxygenase
BKP57_RS04575	COG2986	histidine ammonia-lyase
BKP57_RS04590	COG1228	amidohydrolase
BKP57_RS04595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKP57_RS04600	COG0010	Belongs to the arginase family
BKP57_RS04605	COG0583	DNA-binding transcription factor activity
BKP57_RS04620	COG2176	DNA-directed DNA polymerase activity
BKP57_RS04640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP57_RS04645	COG1757	Na H antiporter
BKP57_RS04655	COG1011	Hydrolase
BKP57_RS04660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP57_RS04665	COG0326	Molecular chaperone. Has ATPase activity
BKP57_RS04680	COG0277	FAD linked oxidase domain protein
BKP57_RS04685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_RS04690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKP57_RS04695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKP57_RS04700	COG2814	Major facilitator Superfamily
BKP57_RS04725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKP57_RS04755	COG1247	-acetyltransferase
BKP57_RS04780	COG4474	Belongs to the UPF0398 family
BKP57_RS04800	COG1970	mechanosensitive ion channel activity
BKP57_RS04810	COG2318	DinB family
BKP57_RS04815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_RS04820	COG1227	inorganic diphosphatase activity
BKP57_RS04825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_RS04835	COG2364	Membrane
BKP57_RS04840	COG0456	acetyltransferase
BKP57_RS04840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKP57_RS04845	COG0768	penicillin binding
BKP57_RS04850	COG1271	oxidase subunit
BKP57_RS04855	COG1294	oxidase, subunit
BKP57_RS04860	COG4988	ABC transporter
BKP57_RS04865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP57_RS04875	COG1408	metallophosphoesterase
BKP57_RS04880	COG0726	polysaccharide deacetylase
BKP57_RS04905	COG1082	Xylose isomerase domain protein TIM barrel
BKP57_RS04910	COG0673	inositol 2-dehydrogenase activity
BKP57_RS04945	COG2390	Transcriptional regulator
BKP57_RS04945	COG4584	PFAM Integrase catalytic
BKP57_RS04950	COG1484	DNA-dependent DNA replication
BKP57_RS04955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_RS04970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BKP57_RS04980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_RS04990	COG0165	Argininosuccinate lyase
BKP57_RS05000	COG0604	alcohol dehydrogenase
BKP57_RS05000	COG3321	synthase
BKP57_RS05160	COG0735	belongs to the Fur family
BKP57_RS05165	COG2096	Adenosyltransferase
BKP57_RS05175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKP57_RS05185	COG0745	RESPONSE REGULATOR receiver
BKP57_RS05190	COG2205	protein histidine kinase activity
BKP57_RS05195	COG1136	(ABC) transporter
BKP57_RS05200	COG0577	efflux transmembrane transporter activity
BKP57_RS05205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP57_RS05215	COG1132	(ABC) transporter
BKP57_RS05220	COG3557	Belongs to the UPF0374 family
BKP57_RS05245	COG1988	membrane-bound metal-dependent
BKP57_RS05255	COG2137	regulation of response to DNA damage stimulus
BKP57_RS05260	COG1090	epimerase
BKP57_RS05275	COG2188	Transcriptional regulator
BKP57_RS05290	COG1131	(ABC) transporter
BKP57_RS05295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_RS05305	COG1131	(ABC) transporter
BKP57_RS05310	COG1725	Transcriptional regulator
BKP57_RS05330	COG0542	response to heat
BKP57_RS05335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_RS05345	COG2056	Na+-H+ antiporter family
BKP57_RS05360	COG0477	Major facilitator Superfamily
BKP57_RS05365	COG0765	amino acid transport
BKP57_RS05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP57_RS05375	COG2217	Heavy metal translocating P-type atpase
BKP57_RS05390	COG1295	ribonuclease BN
BKP57_RS05400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_RS05405	COG1115	amino acid carrier protein
BKP57_RS05410	COG2066	Belongs to the glutaminase family
BKP57_RS05420	COG2340	Cysteine-rich secretory protein family
BKP57_RS05425	COG1077	Cell shape determining protein MreB Mrl
BKP57_RS05430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKP57_RS05435	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS05440	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS05470	COG1414	Transcriptional regulator
BKP57_RS05480	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS05485	COG0028	Belongs to the TPP enzyme family
BKP57_RS05490	COG0436	Aminotransferase
BKP57_RS05495	COG1757	Na H antiporter
BKP57_RS05515	COG0733	neurotransmitter:sodium symporter activity
BKP57_RS05520	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP57_RS05545	COG0488	(ABC) transporter
BKP57_RS05560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_RS05560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_RS05565	COG0307	riboflavin synthase, alpha
BKP57_RS05570	COG0840	transmembrane signaling receptor activity
BKP57_RS05575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS05575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_RS05580	COG0730	response to heat
BKP57_RS05585	COG0425	Belongs to the sulfur carrier protein TusA family
BKP57_RS05590	COG2210	Belongs to the sulfur carrier protein TusA family
BKP57_RS05595	COG0425	Belongs to the sulfur carrier protein TusA family
BKP57_RS05595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_RS05605	COG2210	Belongs to the sulfur carrier protein TusA family
BKP57_RS05615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_RS05620	COG1937	Protein conserved in bacteria
BKP57_RS05625	COG0247	lactate metabolic process
BKP57_RS05630	COG0277	FAD linked oxidase domain protein
BKP57_RS05635	COG3835	regulator
BKP57_RS05650	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS05655	COG0166	Belongs to the GPI family
BKP57_RS05660	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKP57_RS05675	COG1695	Transcriptional regulator
BKP57_RS05690	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS05695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS05710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKP57_RS05710	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BKP57_RS05720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKP57_RS05725	COG2079	MmgE PrpD family protein
BKP57_RS05730	COG0372	Belongs to the citrate synthase family
BKP57_RS05735	COG0583	DNA-binding transcription factor activity
BKP57_RS05745	COG2610	gluconate transmembrane transporter activity
BKP57_RS05750	COG2610	gluconate transmembrane transporter activity
BKP57_RS05755	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKP57_RS05760	COG2814	Major facilitator Superfamily
BKP57_RS05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKP57_RS05780	COG0583	DNA-binding transcription factor activity
BKP57_RS05790	COG3546	catalase activity
BKP57_RS05795	COG0626	cystathionine gamma-synthase activity
BKP57_RS05805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKP57_RS05810	COG1694	Mazg nucleotide pyrophosphohydrolase
BKP57_RS05835	COG1695	Transcriptional regulator
BKP57_RS05850	COG4496	protein, YerC YecD
BKP57_RS05855	COG1757	Na H antiporter
BKP57_RS05860	COG0351	phosphomethylpyrimidine kinase
BKP57_RS05870	COG0531	amino acid
BKP57_RS05875	COG0702	epimerase
BKP57_RS05890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP57_RS05905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS05925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS05925	COG3711	transcriptional antiterminator
BKP57_RS05930	COG2205	protein histidine kinase activity
BKP57_RS05935	COG0745	RESPONSE REGULATOR receiver
BKP57_RS05950	COG1131	(ABC) transporter
BKP57_RS05985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP57_RS05990	COG1597	lipid kinase activity
BKP57_RS05995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP57_RS06000	COG0154	amidase activity
BKP57_RS06005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP57_RS06040	COG4851	CamS sex pheromone cAM373 precursor
BKP57_RS06045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKP57_RS06050	COG0210	DNA helicase
BKP57_RS06055	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BKP57_RS06060	COG4496	protein, YerC YecD
BKP57_RS06065	COG1470	cell adhesion involved in biofilm formation
BKP57_RS06070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKP57_RS06080	COG0151	Belongs to the GarS family
BKP57_RS06085	COG0138	bifunctional purine biosynthesis protein purh
BKP57_RS06090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKP57_RS06095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKP57_RS06100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKP57_RS06105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP57_RS06110	COG0047	phosphoribosylformylglycinamidine synthase activity
BKP57_RS06115	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP57_RS06120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKP57_RS06125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKP57_RS06130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKP57_RS06135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKP57_RS06140	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BKP57_RS06150	COG2258	MOSC domain
BKP57_RS06155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_RS06165	COG0840	transmembrane signaling receptor activity
BKP57_RS06170	COG2252	PERMEase
BKP57_RS06180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP57_RS06185	COG3842	ATPase activity
BKP57_RS06205	COG2826	transposase and inactivated derivatives, IS30 family
BKP57_RS06215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKP57_RS06220	COG0527	aspartate kinase activity
BKP57_RS06225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_RS06225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_RS06230	COG0662	Cupin 2, conserved barrel domain protein
BKP57_RS06240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_RS06250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKP57_RS06255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BKP57_RS06260	COG2207	Transcriptional regulator
BKP57_RS06280	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP57_RS06285	COG2169	Transcriptional regulator
BKP57_RS06290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_RS06300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKP57_RS06340	COG1595	DNA-templated transcription, initiation
BKP57_RS06355	COG1131	(ABC) transporter
BKP57_RS06380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_RS06395	COG0640	Transcriptional regulator
BKP57_RS06405	COG2226	methyltransferase
BKP57_RS06425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKP57_RS06435	COG0641	radical SAM
BKP57_RS06440	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS06450	COG2190	(PTS) system
BKP57_RS06450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS06450	COG1263	PTS System
BKP57_RS06455	COG3711	transcriptional antiterminator
BKP57_RS06485	COG0561	phosphatase activity
BKP57_RS06490	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS06495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS06495	COG2190	(PTS) system
BKP57_RS06495	COG1263	PTS System
BKP57_RS06500	COG3711	transcriptional antiterminator
BKP57_RS06505	COG1486	melibiose metabolic process
BKP57_RS06525	COG0189	ligase activity
BKP57_RS06545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP57_RS06555	COG0693	protein deglycase activity
BKP57_RS06560	COG2378	regulation of single-species biofilm formation
BKP57_RS06565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_RS06595	COG1674	ftsk spoiiie
BKP57_RS06600	COG2946	Replication initiation factor
BKP57_RS06630	COG0791	NLP P60 protein
BKP57_RS06630	COG0741	lytic transglycosylase activity
BKP57_RS06645	COG0210	DNA helicase
BKP57_RS06665	COG1131	(ABC) transporter
BKP57_RS06680	COG0789	Transcriptional regulator
BKP57_RS06685	COG2814	Major facilitator Superfamily
BKP57_RS06745	COG0741	lytic transglycosylase activity
BKP57_RS06745	COG0791	NLP P60 protein
BKP57_RS06750	COG5644	endopeptidase inhibitor activity
BKP57_RS06765	COG0433	COG0433 Predicted ATPase
BKP57_RS06800	COG2946	Replication initiation factor
BKP57_RS06805	COG1674	ftsk spoiiie
BKP57_RS06835	COG1396	sequence-specific DNA binding
BKP57_RS06840	COG2856	Zn peptidase
BKP57_RS06855	COG0519	Catalyzes the synthesis of GMP from XMP
BKP57_RS06855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKP57_RS06860	COG1305	Transglutaminase-like
BKP57_RS06865	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BKP57_RS06870	COG0714	Associated with various cellular activities
BKP57_RS06885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKP57_RS06890	COG0154	amidase activity
BKP57_RS06895	COG0531	amino acid
BKP57_RS06900	COG0697	spore germination
BKP57_RS06915	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS06920	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS06930	COG0601	transmembrane transport
BKP57_RS06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS06940	COG0840	transmembrane signaling receptor activity
BKP57_RS06955	COG2200	EAL domain
BKP57_RS06970	COG1510	regulation of RNA biosynthetic process
BKP57_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS06980	COG1454	alcohol dehydrogenase
BKP57_RS06985	COG2197	response regulator
BKP57_RS06990	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP57_RS06995	COG1442	glycosyl transferase family 8
BKP57_RS07005	COG1263	PTS System
BKP57_RS07005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS07005	COG2190	(PTS) system
BKP57_RS07010	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS07025	COG1757	Na H antiporter
BKP57_RS07030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKP57_RS07035	COG1473	amidohydrolase
BKP57_RS07040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKP57_RS07045	COG1473	amidohydrolase
BKP57_RS07055	COG1879	ABC-type sugar transport system periplasmic component
BKP57_RS07060	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKP57_RS07070	COG1869	D-ribose catabolic process
BKP57_RS07075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_RS07080	COG1609	Transcriptional regulator
BKP57_RS07085	COG0747	negative chemotaxis
BKP57_RS07090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS07095	COG0601	transmembrane transport
BKP57_RS07100	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS07105	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS07120	COG1966	Carbon starvation protein
BKP57_RS07145	COG1115	amino acid carrier protein
BKP57_RS07165	COG5444	nuclease activity
BKP57_RS07220	COG0791	NLP P60 protein
BKP57_RS07220	COG1388	LysM domain
BKP57_RS07230	COG0459	protein refolding
BKP57_RS07235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKP57_RS07240	COG1266	CAAX protease self-immunity
BKP57_RS07250	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKP57_RS07255	COG0488	(ABC) transporter
BKP57_RS07260	COG0772	Belongs to the SEDS family
BKP57_RS07265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKP57_RS07270	COG0456	acetyltransferase
BKP57_RS07275	COG1214	PFAM Peptidase M22, glycoprotease
BKP57_RS07280	COG0802	atpase or kinase
BKP57_RS07285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKP57_RS07375	COG3091	SprT-like family
BKP57_RS07380	COG0753	catalase activity
BKP57_RS07385	COG2183	response to ionizing radiation
BKP57_RS07395	COG2208	phosphoserine phosphatase activity
BKP57_RS07400	COG1191	sigma factor activity
BKP57_RS07405	COG2172	sigma factor antagonist activity
BKP57_RS07410	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_RS07415	COG2208	phosphoserine phosphatase activity
BKP57_RS07420	COG2172	sigma factor antagonist activity
BKP57_RS07425	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_RS07430	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_RS07440	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_RS07455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKP57_RS07460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKP57_RS07460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKP57_RS07465	COG0736	holo-[acyl-carrier-protein] synthase activity
BKP57_RS07470	COG0705	Rhomboid family
BKP57_RS07475	COG1609	Transcriptional regulator
BKP57_RS07485	COG0546	phosphoglycolate phosphatase activity
BKP57_RS07490	COG3428	Bacterial PH domain
BKP57_RS07495	COG3402	PFAM membrane-flanked domain
BKP57_RS07500	COG0513	Belongs to the DEAD box helicase family
BKP57_RS07505	COG0697	spore germination
BKP57_RS07530	COG1846	Transcriptional regulator
BKP57_RS07540	COG4152	abc transporter atp-binding protein
BKP57_RS07545	COG1597	lipid kinase activity
BKP57_RS07555	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP57_RS07560	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS07565	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS07570	COG0737	Belongs to the 5'-nucleotidase family
BKP57_RS07575	COG3212	peptidase
BKP57_RS07585	COG5002	protein histidine kinase activity
BKP57_RS07585	COG3850	Histidine kinase
BKP57_RS07590	COG0745	RESPONSE REGULATOR receiver
BKP57_RS07605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS07615	COG1695	Transcriptional regulator
BKP57_RS07635	COG1131	(ABC) transporter
BKP57_RS07640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_RS07655	COG1217	gtp-binding protein TYPA
BKP57_RS07665	COG0471	metal ion transport
BKP57_RS07670	COG3850	Histidine kinase
BKP57_RS07670	COG5002	protein histidine kinase activity
BKP57_RS07675	COG0745	RESPONSE REGULATOR receiver
BKP57_RS07680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_RS07690	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BKP57_RS07695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP57_RS07785	COG2084	Dehydrogenase
BKP57_RS07800	COG2226	methyltransferase
BKP57_RS07825	COG1263	PTS System
BKP57_RS07825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS07830	COG1486	melibiose metabolic process
BKP57_RS07835	COG1737	Transcriptional regulator
BKP57_RS07855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS07860	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS07865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS07865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS07870	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS07880	COG3344	reverse transcriptase
BKP57_RS07885	COG0363	glucosamine-6-phosphate deaminase activity
BKP57_RS07915	COG3716	PTS system mannose fructose sorbose family IID component
BKP57_RS07920	COG3715	PTS system
BKP57_RS07925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS07930	COG2222	sugar isomerase
BKP57_RS07935	COG2188	Transcriptional regulator
BKP57_RS07965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKP57_RS07970	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKP57_RS07975	COG2017	converts alpha-aldose to the beta-anomer
BKP57_RS07985	COG0494	nUDIX hydrolase
BKP57_RS08005	COG1316	TRANSCRIPTIONal
BKP57_RS08015	COG1316	TRANSCRIPTIONal
BKP57_RS08020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_RS08025	COG0438	transferase activity, transferring glycosyl groups
BKP57_RS08035	COG1216	Glycosyl transferase, family 2
BKP57_RS08050	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_RS08060	COG1682	transport, permease protein
BKP57_RS08075	COG0438	transferase activity, transferring glycosyl groups
BKP57_RS08080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP57_RS08095	COG4193	domain, Protein
BKP57_RS08100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP57_RS08105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKP57_RS08110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP57_RS08115	COG4193	domain, Protein
BKP57_RS08120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BKP57_RS08125	COG2244	polysaccharide biosynthetic process
BKP57_RS08145	COG2076	Multidrug Resistance protein
BKP57_RS08165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_RS08190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKP57_RS08195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_RS08205	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKP57_RS08210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKP57_RS08215	COG0095	Lipoate-protein ligase
BKP57_RS08220	COG1737	Transcriptional regulator
BKP57_RS08225	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BKP57_RS08230	COG2190	(PTS) system
BKP57_RS08230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS08230	COG1263	PTS System
BKP57_RS08235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS08240	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS08245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS08250	COG1486	melibiose metabolic process
BKP57_RS08255	COG2188	Transcriptional regulator
BKP57_RS08260	COG3394	polysaccharide catabolic process
BKP57_RS08275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKP57_RS08280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_RS08320	COG4786	Flagellar basal body rod
BKP57_RS08325	COG4786	Flagellar basal body rod
BKP57_RS08330	COG1077	Cell shape determining protein MreB Mrl
BKP57_RS08335	COG1609	Transcriptional regulator
BKP57_RS08350	COG2385	sporulation resulting in formation of a cellular spore
BKP57_RS08355	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS08360	COG0791	NLP P60 protein
BKP57_RS08365	COG4166	transmembrane transport
BKP57_RS08370	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS08375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS08380	COG0601	transmembrane transport
BKP57_RS08385	COG2362	D-Aminopeptidase
BKP57_RS08390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP57_RS08400	COG4836	Membrane
BKP57_RS08410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKP57_RS08415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKP57_RS08420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKP57_RS08425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKP57_RS08430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP57_RS08435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKP57_RS08440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP57_RS08445	COG0356	it plays a direct role in the translocation of protons across the membrane
BKP57_RS08455	COG1404	Belongs to the peptidase S8 family
BKP57_RS08460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKP57_RS08465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKP57_RS08470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKP57_RS08475	COG4475	Protein of unknown function (DUF436)
BKP57_RS08480	COG0698	ribose 5-phosphate isomerase
BKP57_RS08485	COG0840	transmembrane signaling receptor activity
BKP57_RS08490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_RS08495	COG1971	Probably functions as a manganese efflux pump
BKP57_RS08500	COG0009	L-threonylcarbamoyladenylate synthase
BKP57_RS08520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKP57_RS08525	COG1435	thymidine kinase activity
BKP57_RS08530	COG0254	rRNA binding
BKP57_RS08535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKP57_RS08540	COG1494	fructose-1,6-bisphosphatase
BKP57_RS08545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP57_RS08550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKP57_RS08555	COG0191	fructose-bisphosphate aldolase activity
BKP57_RS08560	COG0745	RESPONSE REGULATOR receiver
BKP57_RS08565	COG0504	CTP synthase activity
BKP57_RS08570	COG3343	RNA polymerase activity
BKP57_RS08575	COG1309	transcriptional regulator
BKP57_RS08580	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS08585	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS08590	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_RS08595	COG0183	Belongs to the thiolase family
BKP57_RS08600	COG2181	nitrate reductase activity
BKP57_RS08600	COG0247	lactate metabolic process
BKP57_RS08605	COG1882	Formate acetyltransferase
BKP57_RS08610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKP57_RS08615	COG0018	arginyl-trna synthetase
BKP57_RS08625	COG0039	L-malate dehydrogenase activity
BKP57_RS08630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_RS08645	COG3465	dGTPase activity
BKP57_RS08650	COG1078	dGTPase activity
BKP57_RS08655	COG0095	Lipoate-protein ligase
BKP57_RS08660	COG0280	phosphate acetyltransferase
BKP57_RS08665	COG3253	May function as heme-dependent peroxidase
BKP57_RS08675	COG3773	Cell wall hydrolase
BKP57_RS08690	COG2363	Small membrane protein
BKP57_RS08700	COG1845	cytochrome c oxidase, subunit III
BKP57_RS08705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP57_RS08710	COG2010	Cytochrome c
BKP57_RS08710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_RS08720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKP57_RS08725	COG3314	Sporulation integral membrane protein YlbJ
BKP57_RS08730	COG3594	Acyltransferase
BKP57_RS08735	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKP57_RS08740	COG1793	dna ligase
BKP57_RS08740	COG3285	dna ligase
BKP57_RS08745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP57_RS08765	COG0861	Integral membrane protein TerC family
BKP57_RS08770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP57_RS08775	COG0628	permease
BKP57_RS08795	COG1114	Component of the transport system for branched-chain amino acids
BKP57_RS08800	COG0514	ATP-dependent DNA helicase (RecQ)
BKP57_RS08810	COG1733	regulation of RNA biosynthetic process
BKP57_RS08815	COG1115	amino acid carrier protein
BKP57_RS08820	COG1607	acyl-coa hydrolase
BKP57_RS08825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP57_RS08830	COG1737	Transcriptional regulator
BKP57_RS08835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKP57_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS08840	COG1263	PTS System
BKP57_RS08845	COG2873	o-acetylhomoserine
BKP57_RS08860	COG0561	phosphatase activity
BKP57_RS08865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS08875	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS08880	COG2755	lipolytic protein G-D-S-L family
BKP57_RS08895	COG0488	(ABC) transporter
BKP57_RS08900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP57_RS08905	COG0156	8-amino-7-oxononanoate synthase activity
BKP57_RS08910	COG3584	3D domain protein
BKP57_RS08910	COG1388	LysM domain
BKP57_RS08920	COG2814	Major facilitator Superfamily
BKP57_RS08925	COG0534	Mate efflux family protein
BKP57_RS08935	COG0251	oxidation-reduction process
BKP57_RS08940	COG0741	lytic transglycosylase activity
BKP57_RS08965	COG2358	TRAP transporter, solute receptor (TAXI family
BKP57_RS09000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKP57_RS09010	COG2070	2-Nitropropane dioxygenase
BKP57_RS09020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP57_RS09030	COG1136	(ABC) transporter
BKP57_RS09040	COG2814	Major facilitator Superfamily
BKP57_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS09055	COG1263	PTS System
BKP57_RS09065	COG1737	Transcriptional regulator
BKP57_RS09070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKP57_RS09075	COG2032	superoxide dismutase activity
BKP57_RS09110	COG4152	abc transporter atp-binding protein
BKP57_RS09125	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP57_RS09130	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS09130	COG3103	Sh3 type 3 domain protein
BKP57_RS09130	COG4991	sh3 domain protein
BKP57_RS09140	COG2226	methyltransferase
BKP57_RS09145	COG4282	regulation of fungal-type cell wall biogenesis
BKP57_RS09150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP57_RS09160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP57_RS09165	COG2323	membrane
BKP57_RS09170	COG3383	formate dehydrogenase (NAD+) activity
BKP57_RS09175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKP57_RS09180	COG0753	catalase activity
BKP57_RS09185	COG3011	Protein conserved in bacteria
BKP57_RS09190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKP57_RS09200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_RS09205	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP57_RS09210	COG0501	Belongs to the peptidase M48B family
BKP57_RS09220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKP57_RS09225	COG0427	acetyl-CoA hydrolase
BKP57_RS09240	COG1252	NADH dehydrogenase
BKP57_RS09250	COG1346	cytolysis
BKP57_RS09255	COG1380	Effector of murein hydrolase LrgA
BKP57_RS09260	COG0137	argininosuccinate synthase activity
BKP57_RS09285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKP57_RS09290	COG0573	inorganic phosphate transmembrane transporter activity
BKP57_RS09295	COG0581	inorganic phosphate transmembrane transporter activity
BKP57_RS09300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP57_RS09330	COG0561	phosphatase activity
BKP57_RS09340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS09340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS09340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS09345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS09345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS09345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS09350	COG1105	Belongs to the carbohydrate kinase PfkB family
BKP57_RS09360	COG0346	lactoylglutathione lyase activity
BKP57_RS09365	COG1011	Hydrolase
BKP57_RS09375	COG0577	efflux transmembrane transporter activity
BKP57_RS09380	COG1136	(ABC) transporter
BKP57_RS09385	COG3871	stress protein (general stress protein 26)
BKP57_RS09405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKP57_RS09430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKP57_RS09435	COG1609	Transcriptional regulator
BKP57_RS09450	COG1131	(ABC) transporter
BKP57_RS09455	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_RS09460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS09460	COG2190	(PTS) system
BKP57_RS09460	COG1263	PTS System
BKP57_RS09465	COG3711	transcriptional antiterminator
BKP57_RS09470	COG1263	PTS System
BKP57_RS09470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS09480	COG4821	SIS domain
BKP57_RS09485	COG2188	Transcriptional regulator
BKP57_RS09505	COG1607	acyl-coa hydrolase
BKP57_RS09510	COG0583	DNA-binding transcription factor activity
BKP57_RS09525	COG0785	Cytochrome C biogenesis protein
BKP57_RS09530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS09535	COG0745	RESPONSE REGULATOR receiver
BKP57_RS09540	COG5002	protein histidine kinase activity
BKP57_RS09555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS09610	COG0583	DNA-binding transcription factor activity
BKP57_RS09615	COG1937	Protein conserved in bacteria
BKP57_RS09625	COG3949	Membrane
BKP57_RS09630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKP57_RS09640	COG2719	SpoVR family
BKP57_RS09645	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP57_RS09650	COG1121	(ABC) transporter
BKP57_RS09655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_RS09655	COG1321	iron dependent repressor
BKP57_RS09660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_RS09670	COG2718	Belongs to the UPF0229 family
BKP57_RS09675	COG2766	serine protein kinase
BKP57_RS09680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_RS09695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKP57_RS09705	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS09710	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS09715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP57_RS09725	COG0613	PHP domain protein
BKP57_RS09730	COG4778	phosphonate C-P lyase system protein PhnL
BKP57_RS09735	COG3454	Phosphonate metabolism
BKP57_RS09740	COG4107	phosphonate C-P lyase system protein PhnK
BKP57_RS09745	COG3627	carbon phosphorus lyase activity
BKP57_RS09775	COG0395	ABC-type sugar transport system, permease component
BKP57_RS09785	COG3842	ATPase activity
BKP57_RS09805	COG0110	maltose O-acetyltransferase activity
BKP57_RS09815	COG0583	DNA-binding transcription factor activity
BKP57_RS09820	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BKP57_RS09825	COG1518	maintenance of DNA repeat elements
BKP57_RS09875	COG2116	formate transmembrane transporter activity
BKP57_RS09880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKP57_RS09895	COG1280	lysine exporter protein (LysE YggA)
BKP57_RS09900	COG3403	YqcI/YcgG family
BKP57_RS09910	COG5577	PFAM Coat F domain
BKP57_RS09915	COG2814	Major facilitator Superfamily
BKP57_RS09925	COG2964	Protein conserved in bacteria
BKP57_RS09935	COG1760	l-serine dehydratase
BKP57_RS09940	COG1760	l-serine dehydratase
BKP57_RS09945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_RS09960	COG1131	(ABC) transporter
BKP57_RS09965	COG0842	Transport permease protein
BKP57_RS09970	COG1309	transcriptional regulator
BKP57_RS09980	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS09985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS09990	COG3711	transcriptional antiterminator
BKP57_RS09990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS09995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS10000	COG1510	regulation of RNA biosynthetic process
BKP57_RS10005	COG1125	glycine betaine transport
BKP57_RS10005	COG0517	IMP dehydrogenase activity
BKP57_RS10010	COG1174	glycine betaine transport
BKP57_RS10015	COG1732	Glycine betaine
BKP57_RS10020	COG1174	glycine betaine transport
BKP57_RS10030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS10030	COG1263	PTS System
BKP57_RS10030	COG2190	(PTS) system
BKP57_RS10035	COG1486	melibiose metabolic process
BKP57_RS10040	COG1737	Transcriptional regulator
BKP57_RS10050	COG2056	Na+-H+ antiporter family
BKP57_RS10055	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP57_RS10060	COG3588	fructose-bisphosphate aldolase
BKP57_RS10065	COG3408	Glycogen debranching enzyme
BKP57_RS10065	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BKP57_RS10070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS10070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS10070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS10090	COG0726	polysaccharide deacetylase
BKP57_RS10110	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP57_RS10115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_RS10120	COG1121	(ABC) transporter
BKP57_RS10125	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS10130	COG1309	transcriptional regulator
BKP57_RS10145	COG2207	Transcriptional regulator
BKP57_RS10145	COG3708	Transcriptional regulator
BKP57_RS10150	COG1794	racemase activity, acting on amino acids and derivatives
BKP57_RS10180	COG1131	(ABC) transporter
BKP57_RS10230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS10245	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS10250	COG1486	melibiose metabolic process
BKP57_RS10255	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS10260	COG3711	transcriptional antiterminator
BKP57_RS10260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS10290	COG3773	Cell wall hydrolase
BKP57_RS10305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKP57_RS10340	COG0586	Pfam SNARE associated Golgi protein
BKP57_RS10345	COG0688	phosphatidylethanolamine metabolic process
BKP57_RS10350	COG1183	phosphatidylcholine synthase activity
BKP57_RS10370	COG2027	D-alanyl-D-alanine carboxypeptidase
BKP57_RS10380	COG3266	domain, Protein
BKP57_RS10380	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BKP57_RS10380	COG4932	domain protein
BKP57_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS10395	COG0406	alpha-ribazole phosphatase activity
BKP57_RS10410	COG0529	Catalyzes the synthesis of activated sulfate
BKP57_RS10415	COG3273	potassium ion transport
BKP57_RS10415	COG0471	metal ion transport
BKP57_RS10420	COG2046	Belongs to the sulfate adenylyltransferase family
BKP57_RS10445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP57_RS10450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKP57_RS10455	COG0175	sulfate reduction
BKP57_RS10460	COG2076	Multidrug Resistance protein
BKP57_RS10465	COG2076	Multidrug Resistance protein
BKP57_RS10470	COG1309	transcriptional regulator
BKP57_RS10480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS10485	COG0450	alkyl hydroperoxide reductase
BKP57_RS10490	COG1132	(ABC) transporter
BKP57_RS10500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_RS10505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKP57_RS10510	COG4853	Protein conserved in bacteria
BKP57_RS10515	COG4863	YycH protein
BKP57_RS10520	COG5002	protein histidine kinase activity
BKP57_RS10525	COG0745	RESPONSE REGULATOR receiver
BKP57_RS10530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKP57_RS10535	COG0305	Participates in initiation and elongation during chromosome replication
BKP57_RS10540	COG0359	binds to the 23S rRNA
BKP57_RS10545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BKP57_RS10560	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKP57_RS10585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKP57_RS10590	COG0629	single-stranded DNA binding
BKP57_RS10595	COG0360	Binds together with S18 to 16S ribosomal RNA
BKP57_RS10600	COG0012	GTP binding
BKP57_RS10605	COG4481	Protein conserved in bacteria
BKP57_RS10610	COG0668	transmembrane transport
BKP57_RS10615	COG3949	Membrane
BKP57_RS10630	COG1475	DNA binding
BKP57_RS10635	COG1192	Involved in chromosome partitioning
BKP57_RS10640	COG1475	DNA binding
BKP57_RS10645	COG0357	Ribosomal RNA small subunit methyltransferase G
BKP57_RS10650	COG0445	tRNA wobble uridine modification
BKP57_RS10655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKP57_RS10660	COG1847	R3H domain protein
BKP57_RS10665	COG0706	membrane insertase activity
BKP57_RS10670	COG0594	ribonuclease P activity
BKP57_RS10675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKP57_RS10680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKP57_RS10685	COG0592	DNA-directed DNA polymerase activity
BKP57_RS10690	COG2501	S4 domain
BKP57_RS10695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_RS10705	COG0187	DNA topoisomerase II activity
BKP57_RS10710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP57_RS10715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BKP57_RS10725	COG0517	IMP dehydrogenase activity
BKP57_RS10725	COG0516	GMP reductase activity
BKP57_RS10735	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKP57_RS10740	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKP57_RS10745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKP57_RS10755	COG2076	Multidrug Resistance protein
BKP57_RS10760	COG2076	Multidrug Resistance protein
BKP57_RS10765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKP57_RS10770	COG2011	ABC-type metal ion transport system permease component
BKP57_RS10775	COG1464	Belongs to the NlpA lipoprotein family
BKP57_RS10795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKP57_RS10800	COG1428	Deoxynucleoside kinase
BKP57_RS10805	COG1428	Deoxynucleoside kinase
BKP57_RS10815	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_RS10830	COG3959	Transketolase, thiamine diphosphate binding domain
BKP57_RS10835	COG3958	Transketolase
BKP57_RS10845	COG1454	alcohol dehydrogenase
BKP57_RS10860	COG2390	Transcriptional regulator
BKP57_RS10880	COG1595	DNA-templated transcription, initiation
BKP57_RS10885	COG1737	Transcriptional regulator
BKP57_RS10895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS10895	COG1263	PTS System
BKP57_RS10900	COG1486	melibiose metabolic process
BKP57_RS10905	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS10910	COG1876	peptidase activity
BKP57_RS10915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKP57_RS10925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS10930	COG0601	transmembrane transport
BKP57_RS10935	COG0747	negative chemotaxis
BKP57_RS10940	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS10945	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS10955	COG1418	mRNA catabolic process
BKP57_RS10960	COG2814	Major facilitator Superfamily
BKP57_RS10965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKP57_RS10970	COG1301	dicarboxylic acid transport
BKP57_RS10975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_RS10990	COG1017	nitric oxide dioxygenase activity
BKP57_RS10990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKP57_RS10995	COG1959	2 iron, 2 sulfur cluster binding
BKP57_RS11000	COG0693	protein deglycase activity
BKP57_RS11005	COG3858	chitin binding
BKP57_RS11005	COG1388	LysM domain
BKP57_RS11010	COG1335	isochorismatase
BKP57_RS11015	COG0590	tRNA wobble adenosine to inosine editing
BKP57_RS11025	COG0288	reversible hydration of carbon dioxide
BKP57_RS11030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKP57_RS11035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKP57_RS11040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKP57_RS11060	COG1982	Orn Lys Arg decarboxylase major
BKP57_RS11065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKP57_RS11070	COG3870	Protein conserved in bacteria
BKP57_RS11075	COG1728	Protein conserved in bacteria
BKP57_RS11080	COG0470	DNA polymerase III
BKP57_RS11085	COG1774	PSP1 C-terminal conserved region
BKP57_RS11090	COG4467	Involved in initiation control of chromosome replication
BKP57_RS11095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKP57_RS11100	COG2827	Endonuclease containing a URI domain
BKP57_RS11105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKP57_RS11110	COG2002	toxin-antitoxin pair type II binding
BKP57_RS11120	COG0084	hydrolase, TatD family'
BKP57_RS11125	COG3583	domain protein
BKP57_RS11125	COG3584	3D domain protein
BKP57_RS11135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKP57_RS11145	COG4466	Protein conserved in bacteria
BKP57_RS11155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKP57_RS11160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_RS11165	COG2088	sporulation resulting in formation of a cellular spore
BKP57_RS11170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKP57_RS11175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKP57_RS11180	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKP57_RS11185	COG0193	aminoacyl-tRNA hydrolase activity
BKP57_RS11195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKP57_RS11200	COG2002	toxin-antitoxin pair type II binding
BKP57_RS11205	COG2244	polysaccharide biosynthetic process
BKP57_RS11210	COG3956	TIGRFAM MazG family protein
BKP57_RS11215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKP57_RS11235	COG1098	S1 RNA binding domain
BKP57_RS11250	COG2208	phosphoserine phosphatase activity
BKP57_RS11255	COG2304	oxidoreductase activity
BKP57_RS11260	COG0515	serine threonine protein kinase
BKP57_RS11265	COG0037	tRNA processing
BKP57_RS11270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BKP57_RS11275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP57_RS11280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKP57_RS11285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKP57_RS11290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP57_RS11295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_RS11300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKP57_RS11305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKP57_RS11310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKP57_RS11315	COG1396	sequence-specific DNA binding
BKP57_RS11320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKP57_RS11400	COG1285	pathogenesis
BKP57_RS11410	COG3880	PFAM UvrB UvrC protein
BKP57_RS11415	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BKP57_RS11420	COG0542	response to heat
BKP57_RS11425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKP57_RS11430	COG4956	integral membrane protein (PIN domain superfamily)
BKP57_RS11435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKP57_RS11440	COG1045	serine acetyltransferase
BKP57_RS11445	COG0215	cysteine-tRNA ligase activity
BKP57_RS11455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP57_RS11460	COG3688	RNA-binding protein containing a PIN domain
BKP57_RS11470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP57_RS11475	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP57_RS11480	COG0250	Participates in transcription elongation, termination and antitermination
BKP57_RS11485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP57_RS11490	COG0081	regulation of translation
BKP57_RS11495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKP57_RS11500	COG0222	ribosome binding
BKP57_RS11505	COG2813	Specifically methylates the guanine in position
BKP57_RS11510	COG0085	RNA polymerase activity
BKP57_RS11515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKP57_RS11525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKP57_RS11530	COG0049	tRNA binding
BKP57_RS11535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKP57_RS11540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKP57_RS11550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKP57_RS11555	COG0088	Forms part of the polypeptide exit tunnel
BKP57_RS11560	COG0089	rRNA binding
BKP57_RS11565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKP57_RS11570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKP57_RS11575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKP57_RS11580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKP57_RS11585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKP57_RS11590	COG0255	Belongs to the universal ribosomal protein uL29 family
BKP57_RS11595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKP57_RS11600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKP57_RS11605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKP57_RS11610	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKP57_RS11615	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP57_RS11620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKP57_RS11625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKP57_RS11630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKP57_RS11635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKP57_RS11640	COG1841	ribosomal large subunit assembly
BKP57_RS11645	COG0200	Binds to the 23S rRNA
BKP57_RS11650	COG0201	protein transport
BKP57_RS11655	COG0563	adenylate kinase activity
BKP57_RS11660	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BKP57_RS11665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKP57_RS11670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKP57_RS11675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKP57_RS11680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKP57_RS11685	COG0202	RNA polymerase activity
BKP57_RS11690	COG0203	ribosomal protein L17
BKP57_RS11695	COG1122	ATPase activity
BKP57_RS11700	COG1122	ATPase activity
BKP57_RS11705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKP57_RS11710	COG0101	tRNA pseudouridine synthase activity
BKP57_RS11715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKP57_RS11720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKP57_RS11735	COG1395	domain, Protein
BKP57_RS11790	COG3711	transcriptional antiterminator
BKP57_RS11795	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS11800	COG1263	PTS System
BKP57_RS11800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS11800	COG2190	(PTS) system
BKP57_RS11845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_RS11850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_RS11855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP57_RS11860	COG1120	ATPase activity
BKP57_RS11865	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS11890	COG1349	DNA-binding transcription factor activity
BKP57_RS11905	COG1070	Carbohydrate kinase
BKP57_RS11915	COG2211	Major facilitator Superfamily
BKP57_RS11925	COG2271	Major facilitator Superfamily
BKP57_RS11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS11950	COG1263	PTS System
BKP57_RS11965	COG0385	Bile acid
BKP57_RS11985	COG1979	alcohol dehydrogenase
BKP57_RS11990	COG1349	DNA-binding transcription factor activity
BKP57_RS12010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKP57_RS12020	COG2130	NADP-dependent
BKP57_RS12025	COG0714	Associated with various cellular activities
BKP57_RS12030	COG4548	von Willebrand factor, type A
BKP57_RS12050	COG1295	ribonuclease BN
BKP57_RS12070	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS12075	COG0489	protein tyrosine kinase activity
BKP57_RS12085	COG2194	sulfuric ester hydrolase activity
BKP57_RS12095	COG0726	polysaccharide deacetylase
BKP57_RS12140	COG4974	Belongs to the 'phage' integrase family
BKP57_RS12145	COG2856	Zn peptidase
BKP57_RS12195	COG2217	Heavy metal translocating P-type atpase
BKP57_RS12205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP57_RS12215	COG1131	(ABC) transporter
BKP57_RS12225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKP57_RS12225	COG0646	methionine synthase
BKP57_RS12230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP57_RS12235	COG2856	Zn peptidase
BKP57_RS12250	COG3677	Transposase
BKP57_RS12260	COG5434	Belongs to the glycosyl hydrolase 28 family
BKP57_RS12280	COG0791	NLP P60 protein
BKP57_RS12280	COG1388	LysM domain
BKP57_RS12330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKP57_RS12360	COG1595	DNA-templated transcription, initiation
BKP57_RS12365	COG5662	AntiSigma factor
BKP57_RS12370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKP57_RS12380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP57_RS12395	COG1349	DNA-binding transcription factor activity
BKP57_RS12405	COG0698	ribose 5-phosphate isomerase
BKP57_RS12430	COG0191	fructose-bisphosphate aldolase activity
BKP57_RS12445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_RS12455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_RS12485	COG5002	protein histidine kinase activity
BKP57_RS12485	COG3850	Histidine kinase
BKP57_RS12490	COG3344	reverse transcriptase
BKP57_RS12495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_RS12505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_RS12520	COG1136	(ABC) transporter
BKP57_RS12525	COG0577	efflux transmembrane transporter activity
BKP57_RS12530	COG0745	RESPONSE REGULATOR receiver
BKP57_RS12535	COG2205	protein histidine kinase activity
BKP57_RS12545	COG2207	Transcriptional regulator
BKP57_RS12555	COG2124	cytochrome p450
BKP57_RS12565	COG3655	Transcriptional regulator
BKP57_RS12570	COG3739	integral membrane protein
BKP57_RS12605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP57_RS12620	COG1596	polysaccharide export
BKP57_RS12620	COG1555	photosystem II stabilization
BKP57_RS12625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKP57_RS12630	COG2188	Transcriptional regulator
BKP57_RS12650	COG4821	SIS domain
BKP57_RS12655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS12695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP57_RS12700	COG2169	Transcriptional regulator
BKP57_RS12705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKP57_RS12725	COG2843	Capsule synthesis protein
BKP57_RS12750	COG0456	acetyltransferase
BKP57_RS12755	COG1280	lysine exporter protein (LysE YggA)
BKP57_RS12765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP57_RS12770	COG1136	(ABC) transporter
BKP57_RS12775	COG0577	efflux transmembrane transporter activity
BKP57_RS12780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP57_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS12810	COG3189	MarR family transcriptional regulator
BKP57_RS12825	COG1309	transcriptional regulator
BKP57_RS12845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP57_RS12855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP57_RS12860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKP57_RS12865	COG0746	molybdenum cofactor guanylyltransferase activity
BKP57_RS12870	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKP57_RS12875	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKP57_RS12880	COG4149	molybdate abc transporter
BKP57_RS12885	COG0315	cyclic pyranopterin monophosphate synthase activity
BKP57_RS12895	COG2223	nitrite transmembrane transporter activity
BKP57_RS12900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKP57_RS12905	COG1140	nitrate reductase beta subunit
BKP57_RS12910	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKP57_RS12915	COG2181	nitrate reductase activity
BKP57_RS12920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP57_RS12925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP57_RS12945	COG0456	acetyltransferase
BKP57_RS12950	COG1136	(ABC) transporter
BKP57_RS12970	COG0662	Cupin 2, conserved barrel domain protein
BKP57_RS12975	COG3634	alkyl hydroperoxide reductase activity
BKP57_RS12980	COG0450	alkyl hydroperoxide reductase
BKP57_RS12985	COG1115	amino acid carrier protein
BKP57_RS12990	COG4187	Peptidase family M20/M25/M40
BKP57_RS12995	COG2205	protein histidine kinase activity
BKP57_RS13000	COG0745	RESPONSE REGULATOR receiver
BKP57_RS13005	COG2311	Membrane
BKP57_RS13020	COG2723	6-phospho-beta-galactosidase activity
BKP57_RS13025	COG1940	carbohydrate kinase activity
BKP57_RS13035	COG0383	alpha-mannosidase activity
BKP57_RS13040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS13045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS13045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS13045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS13050	COG1131	(ABC) transporter
BKP57_RS13060	COG1733	regulation of RNA biosynthetic process
BKP57_RS13070	COG0666	response to abiotic stimulus
BKP57_RS13075	COG0456	acetyltransferase
BKP57_RS13080	COG0590	tRNA wobble adenosine to inosine editing
BKP57_RS13085	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS13090	COG1395	domain, Protein
BKP57_RS13125	COG0109	protoheme IX farnesyltransferase activity
BKP57_RS13130	COG1253	flavin adenine dinucleotide binding
BKP57_RS13135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP57_RS13140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS13145	COG2226	methyltransferase
BKP57_RS13150	COG1328	CTP reductase activity
BKP57_RS13170	COG1801	Protein of unknown function DUF72
BKP57_RS13175	COG0395	ABC-type sugar transport system, permease component
BKP57_RS13180	COG1175	transmembrane transport
BKP57_RS13185	COG1653	transport
BKP57_RS13190	COG0366	Alpha amylase catalytic
BKP57_RS13195	COG1609	Transcriptional regulator
BKP57_RS13200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_RS13210	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKP57_RS13225	COG3766	membrane
BKP57_RS13235	COG1842	Phage shock protein A
BKP57_RS13245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP57_RS13255	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKP57_RS13260	COG1122	ATPase activity
BKP57_RS13265	COG4721	ABC-type cobalt transport system, permease component
BKP57_RS13295	COG0833	amino acid
BKP57_RS13300	COG1802	Transcriptional regulator
BKP57_RS13335	COG1757	Na H antiporter
BKP57_RS13360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_RS13395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP57_RS13400	COG4974	Belongs to the 'phage' integrase family
BKP57_RS13505	COG1484	DNA-dependent DNA replication
BKP57_RS13790	COG1695	Transcriptional regulator
BKP57_RS13805	COG1388	LysM domain
BKP57_RS13810	COG5002	protein histidine kinase activity
BKP57_RS13815	COG0745	RESPONSE REGULATOR receiver
BKP57_RS13830	COG3973	AAA domain
BKP57_RS13850	COG0616	signal peptide processing
BKP57_RS13855	COG1714	RDD family
BKP57_RS13860	COG1271	oxidase subunit
BKP57_RS13865	COG1294	oxidase, subunit
BKP57_RS13870	COG4988	ABC transporter
BKP57_RS13875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP57_RS13880	COG0745	RESPONSE REGULATOR receiver
BKP57_RS13880	COG2972	Histidine kinase
BKP57_RS13885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP57_RS13885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP57_RS13890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_RS13890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_RS13900	COG1131	(ABC) transporter
BKP57_RS13905	COG3559	Exporter of polyketide antibiotics
BKP57_RS13910	COG1132	(ABC) transporter
BKP57_RS13915	COG1114	Component of the transport system for branched-chain amino acids
BKP57_RS13920	COG1802	Transcriptional regulator
BKP57_RS13940	COG0535	radical SAM domain protein
BKP57_RS13950	COG0668	transmembrane transport
BKP57_RS13965	COG0400	carboxylic ester hydrolase activity
BKP57_RS13970	COG1846	Transcriptional regulator
BKP57_RS13975	COG0488	(ABC) transporter
BKP57_RS13980	COG2188	Transcriptional regulator
BKP57_RS13985	COG0366	Alpha amylase catalytic
BKP57_RS13990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS13990	COG1263	PTS System
BKP57_RS14000	COG1413	lyase activity
BKP57_RS14005	COG1607	acyl-coa hydrolase
BKP57_RS14025	COG3250	beta-galactosidase activity
BKP57_RS14030	COG0531	amino acid
BKP57_RS14045	COG1131	(ABC) transporter
BKP57_RS14070	COG5444	nuclease activity
BKP57_RS14075	COG0346	lactoylglutathione lyase activity
BKP57_RS14080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKP57_RS14085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP57_RS14090	COG0083	homoserine kinase activity
BKP57_RS14095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKP57_RS14100	COG0460	homoserine dehydrogenase
BKP57_RS14110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP57_RS14115	COG1620	l-lactate permease
BKP57_RS14120	COG2186	Transcriptional regulator
BKP57_RS14125	COG0247	lactate metabolic process
BKP57_RS14130	COG1139	Iron-sulfur cluster binding protein
BKP57_RS14135	COG1556	Lactate utilization protein
BKP57_RS14155	COG0477	Major facilitator Superfamily
BKP57_RS14160	COG0789	Transcriptional regulator
BKP57_RS14165	COG0352	thiamine-phosphate diphosphorylase activity
BKP57_RS14170	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BKP57_RS14185	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS14190	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS14195	COG0747	negative chemotaxis
BKP57_RS14205	COG0601	transmembrane transport
BKP57_RS14210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS14230	COG0737	Belongs to the 5'-nucleotidase family
BKP57_RS14230	COG4085	toxin activity
BKP57_RS14230	COG1525	nuclease
BKP57_RS14235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKP57_RS14240	COG0157	Belongs to the NadC ModD family
BKP57_RS14245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKP57_RS14250	COG1104	cysteine desulfurase activity
BKP57_RS14255	COG1827	regulation of RNA biosynthetic process
BKP57_RS14275	COG3104	oligopeptide transport
BKP57_RS14300	COG4145	pantothenate transmembrane transporter activity
BKP57_RS14305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_RS14310	COG0693	protein deglycase activity
BKP57_RS14355	COG5506	Protein of unknown function (DUF1694)
BKP57_RS14395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS14405	COG2201	protein-glutamate methylesterase activity
BKP57_RS14425	COG4869	propanediol catabolic process
BKP57_RS14435	COG1454	alcohol dehydrogenase
BKP57_RS14435	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS14445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKP57_RS14450	COG1882	Formate acetyltransferase
BKP57_RS14465	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BKP57_RS14480	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BKP57_RS14490	COG0708	Exodeoxyribonuclease III
BKP57_RS14495	COG1725	Transcriptional regulator
BKP57_RS14500	COG1131	(ABC) transporter
BKP57_RS14515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS14525	COG1136	(ABC) transporter
BKP57_RS14535	COG0159	tryptophan synthase activity
BKP57_RS14540	COG0133	tryptophan synthase activity
BKP57_RS14545	COG0135	phosphoribosylanthranilate isomerase activity
BKP57_RS14550	COG0134	indole-3-glycerol-phosphate synthase activity
BKP57_RS14555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKP57_RS14565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKP57_RS14575	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP57_RS14580	COG0778	Nitroreductase
BKP57_RS14610	COG0519	Catalyzes the synthesis of GMP from XMP
BKP57_RS14615	COG0840	transmembrane signaling receptor activity
BKP57_RS14635	COG1136	(ABC) transporter
BKP57_RS14655	COG0656	L-ascorbic acid biosynthetic process
BKP57_RS14665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP57_RS14675	COG1304	FMN binding
BKP57_RS14680	COG4876	unkown
BKP57_RS14685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_RS14690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKP57_RS14695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_RS14700	COG4605	iron ion homeostasis
BKP57_RS14705	COG4604	ABC transporter, ATP-binding protein
BKP57_RS14710	COG4607	ABC-type enterochelin transport system periplasmic component
BKP57_RS14715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP57_RS14720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKP57_RS14725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKP57_RS14725	COG0140	phosphoribosyl-ATP diphosphatase activity
BKP57_RS14730	COG0107	imidazoleglycerol-phosphate synthase activity
BKP57_RS14735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKP57_RS14740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKP57_RS14745	COG0131	Imidazoleglycerol-phosphate dehydratase
BKP57_RS14750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKP57_RS14755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKP57_RS14760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKP57_RS14780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKP57_RS14790	COG1126	abc transporter atp-binding protein
BKP57_RS14795	COG0765	amino acid transport
BKP57_RS14800	COG0765	amino acid transport
BKP57_RS14810	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKP57_RS14815	COG2610	gluconate transmembrane transporter activity
BKP57_RS14845	COG3381	protein complex oligomerization
BKP57_RS14850	COG0243	molybdopterin cofactor binding
BKP57_RS14855	COG0437	4 iron, 4 sulfur cluster binding
BKP57_RS14870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP57_RS14875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP57_RS14885	COG0673	inositol 2-dehydrogenase activity
BKP57_RS14890	COG1876	peptidase activity
BKP57_RS14895	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP57_RS14900	COG2839	Protein conserved in bacteria
BKP57_RS14905	COG1335	isochorismatase
BKP57_RS14915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_RS14925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP57_RS14930	COG0765	amino acid transport
BKP57_RS14935	COG1126	abc transporter atp-binding protein
BKP57_RS14940	COG0386	Belongs to the glutathione peroxidase family
BKP57_RS14945	COG0840	transmembrane signaling receptor activity
BKP57_RS14950	COG1054	Belongs to the UPF0176 family
BKP57_RS14955	COG1454	alcohol dehydrogenase
BKP57_RS14960	COG3254	rhamnose metabolic process
BKP57_RS14965	COG2814	Major facilitator Superfamily
BKP57_RS14970	COG1070	Carbohydrate kinase
BKP57_RS14975	COG4806	L-rhamnose isomerase
BKP57_RS14980	COG0235	Class ii aldolase
BKP57_RS14985	COG1349	DNA-binding transcription factor activity
BKP57_RS14995	COG0840	transmembrane signaling receptor activity
BKP57_RS15005	COG0300	oxidoreductase activity
BKP57_RS15010	COG3829	transcription factor binding
BKP57_RS15025	COG1268	BioY protein
BKP57_RS15035	COG1937	Protein conserved in bacteria
BKP57_RS15040	COG2217	Heavy metal translocating P-type atpase
BKP57_RS15060	COG0432	Pfam Uncharacterised protein family UPF0047
BKP57_RS15070	COG1388	LysM domain
BKP57_RS15070	COG0791	NLP P60 protein
BKP57_RS15075	COG3944	biosynthesis protein
BKP57_RS15080	COG0489	protein tyrosine kinase activity
BKP57_RS15085	COG4464	protein tyrosine phosphatase activity
BKP57_RS15100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP57_RS15105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP57_RS15110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKP57_RS15120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP57_RS15155	COG0686	Belongs to the AlaDH PNT family
BKP57_RS15165	COG1316	TRANSCRIPTIONal
BKP57_RS15175	COG3279	Response regulator of the LytR AlgR family
BKP57_RS15215	COG1414	Transcriptional regulator
BKP57_RS15220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_RS15230	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_RS15235	COG2814	Major facilitator Superfamily
BKP57_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS15250	COG3386	PFAM SMP-30 Gluconolaconase
BKP57_RS15260	COG3290	protein histidine kinase activity
BKP57_RS15265	COG4565	transcriptional regulatory protein
BKP57_RS15270	COG2851	Citrate transporter
BKP57_RS15310	COG3732	PTS system glucitol sorbitol-specific
BKP57_RS15325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS15325	COG3711	transcriptional antiterminator
BKP57_RS15330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS15330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS15330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS15340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS15345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP57_RS15350	COG2188	Transcriptional regulator
BKP57_RS15355	COG1486	melibiose metabolic process
BKP57_RS15360	COG3394	polysaccharide catabolic process
BKP57_RS15365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS15365	COG1263	PTS System
BKP57_RS15370	COG3344	reverse transcriptase
BKP57_RS15375	COG1595	DNA-templated transcription, initiation
BKP57_RS15385	COG1131	(ABC) transporter
BKP57_RS15400	COG3876	Protein conserved in bacteria
BKP57_RS15415	COG1737	Transcriptional regulator
BKP57_RS15425	COG0456	acetyltransferase
BKP57_RS15430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP57_RS15435	COG0384	phenazine biosynthesis protein PhzF
BKP57_RS15440	COG0840	transmembrane signaling receptor activity
BKP57_RS15445	COG1757	Na H antiporter
BKP57_RS15460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKP57_RS15490	COG0463	Glycosyl transferase, family 2
BKP57_RS15500	COG4485	Bacterial membrane protein, YfhO
BKP57_RS15505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKP57_RS15530	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS15540	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_RS15545	COG1024	Enoyl-CoA hydratase
BKP57_RS15550	COG0183	Belongs to the thiolase family
BKP57_RS15555	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS15560	COG0824	Thioesterase
BKP57_RS15575	COG1414	Transcriptional regulator
BKP57_RS15580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP57_RS15590	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP57_RS15655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP57_RS15660	COG0523	cobalamin synthesis protein
BKP57_RS15680	COG1136	(ABC) transporter
BKP57_RS15685	COG2205	protein histidine kinase activity
BKP57_RS15690	COG0745	RESPONSE REGULATOR receiver
BKP57_RS15700	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_RS15735	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_RS15740	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_RS15770	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_RS15790	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_RS15815	COG0717	Belongs to the dCTP deaminase family
BKP57_RS15825	COG1396	sequence-specific DNA binding
BKP57_RS15835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP57_RS15840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP57_RS15840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKP57_RS15845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKP57_RS15845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKP57_RS15850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP57_RS15855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_RS15860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_RS15905	COG0702	epimerase
BKP57_RS15940	COG3715	PTS system
BKP57_RS15945	COG3716	PTS system mannose fructose sorbose family IID component
BKP57_RS15950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_RS15965	COG1396	sequence-specific DNA binding
BKP57_RS15990	COG1929	Belongs to the glycerate kinase type-1 family
BKP57_RS15995	COG2610	gluconate transmembrane transporter activity
BKP57_RS16000	COG3835	regulator
BKP57_RS16005	COG0018	arginyl-trna synthetase
BKP57_RS16015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP57_RS16025	COG0549	Belongs to the carbamate kinase family
BKP57_RS16030	COG1438	arginine binding
BKP57_RS16040	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_RS16050	COG1063	alcohol dehydrogenase
BKP57_RS16055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKP57_RS16065	COG4509	Sortase family
BKP57_RS16070	COG1120	ATPase activity
BKP57_RS16085	COG5386	Cell surface protein
BKP57_RS16090	COG5386	Cell surface protein
BKP57_RS16095	COG5386	Cell surface protein
BKP57_RS16100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP57_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_RS16115	COG2329	Antibiotic biosynthesis monooxygenase
BKP57_RS16125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS16125	COG3711	transcriptional antiterminator
BKP57_RS16130	COG1486	melibiose metabolic process
BKP57_RS16140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_RS16150	COG3876	Protein conserved in bacteria
BKP57_RS16175	COG1215	transferase activity, transferring glycosyl groups
BKP57_RS16185	COG0006	proline dipeptidase activity
BKP57_RS16190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_RS16195	COG0583	DNA-binding transcription factor activity
BKP57_RS16210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKP57_RS16220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_RS16235	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_RS16240	COG3775	system Galactitol-specific IIC component
BKP57_RS16255	COG1105	Belongs to the carbohydrate kinase PfkB family
BKP57_RS16260	COG0235	Class ii aldolase
BKP57_RS16275	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS16285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BKP57_RS16290	COG3396	Phenylacetate-CoA oxygenase
BKP57_RS16305	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP57_RS16320	COG1024	Enoyl-CoA hydratase
BKP57_RS16325	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS16330	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_RS16335	COG0183	Belongs to the thiolase family
BKP57_RS16340	COG1024	Enoyl-CoA hydratase
BKP57_RS16345	COG3327	negative regulation of DNA-templated transcription, initiation
BKP57_RS16370	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_RS16385	COG4977	sequence-specific DNA binding
BKP57_RS16385	COG1917	Cupin 2, conserved barrel domain protein
BKP57_RS16390	COG1454	alcohol dehydrogenase
BKP57_RS16390	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS16395	COG3279	Response regulator of the LytR AlgR family
BKP57_RS16430	COG1309	transcriptional regulator
BKP57_RS16435	COG4708	membrane
BKP57_RS16440	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS16465	COG2508	Transcriptional regulator
BKP57_RS16475	COG0145	ligase activity
BKP57_RS16485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKP57_RS16510	COG4126	flavin adenine dinucleotide binding
BKP57_RS16515	COG0697	spore germination
BKP57_RS16530	COG3290	protein histidine kinase activity
BKP57_RS16535	COG4565	transcriptional regulatory protein
BKP57_RS16560	COG0789	Transcriptional regulator
BKP57_RS16565	COG1764	response to oxidative stress
BKP57_RS16570	COG1609	Transcriptional regulator
BKP57_RS16580	COG1621	beta-fructofuranosidase activity
BKP57_RS16585	COG1940	carbohydrate kinase activity
BKP57_RS16590	COG1263	PTS System
BKP57_RS16590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS16595	COG1263	PTS System
BKP57_RS16595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS16615	COG3142	Participates in the control of copper homeostasis
BKP57_RS16630	COG1523	belongs to the glycosyl hydrolase 13 family
BKP57_RS16635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKP57_RS16640	COG0402	S-adenosylhomocysteine deaminase activity
BKP57_RS16650	COG0428	transporter
BKP57_RS16655	COG3775	system Galactitol-specific IIC component
BKP57_RS16660	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_RS16665	COG1999	signal sequence binding
BKP57_RS16670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKP57_RS16685	COG0352	thiamine-phosphate diphosphorylase activity
BKP57_RS16690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_RS16700	COG2022	thiamine diphosphate biosynthetic process
BKP57_RS16705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP57_RS16710	COG1119	ATPase activity
BKP57_RS16715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_RS16720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_RS16725	COG1918	ferrous iron import across plasma membrane
BKP57_RS16725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_RS16730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_RS16735	COG3223	Belongs to the PsiE family
BKP57_RS16745	COG0745	RESPONSE REGULATOR receiver
BKP57_RS16750	COG5002	protein histidine kinase activity
BKP57_RS16760	COG3764	Sortase (surface protein transpeptidase)
BKP57_RS16765	COG0436	Aminotransferase
BKP57_RS16770	COG1309	transcriptional regulator
BKP57_RS16785	COG0183	Belongs to the thiolase family
BKP57_RS16790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKP57_RS16795	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS16800	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS16825	COG1063	alcohol dehydrogenase
BKP57_RS16830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_RS16845	COG2706	6-phosphogluconolactonase activity
BKP57_RS16850	COG3711	transcriptional antiterminator
BKP57_RS16870	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_RS16880	COG4821	SIS domain
BKP57_RS16890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_RS16895	COG1737	Transcriptional regulator
BKP57_RS16900	COG1234	tRNA 3'-trailer cleavage
BKP57_RS16915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_RS16920	COG0444	Belongs to the ABC transporter superfamily
BKP57_RS16925	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS16930	COG2814	Major facilitator Superfamily
BKP57_RS16935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKP57_RS16950	COG1473	amidohydrolase
BKP57_RS16955	COG1288	antiporter activity
BKP57_RS16960	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_RS16965	COG2985	domain, Protein
BKP57_RS16965	COG0490	domain, Protein
BKP57_RS16970	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKP57_RS16980	COG3711	transcriptional antiterminator
BKP57_RS16985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_RS16985	COG2190	(PTS) system
BKP57_RS16985	COG1263	PTS System
BKP57_RS16990	COG1486	melibiose metabolic process
BKP57_RS16995	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS17000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS17000	COG3711	transcriptional antiterminator
BKP57_RS17005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS17005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS17005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_RS17010	COG1482	cell wall glycoprotein biosynthetic process
BKP57_RS17020	COG3263	regulation of cellular component size
BKP57_RS17025	COG0656	L-ascorbic acid biosynthetic process
BKP57_RS17035	COG0129	dihydroxy-acid dehydratase activity
BKP57_RS17040	COG0028	Belongs to the TPP enzyme family
BKP57_RS17045	COG0440	acetolactate synthase activity
BKP57_RS17050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKP57_RS17055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_RS17060	COG0473	3-isopropylmalate dehydrogenase activity
BKP57_RS17065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKP57_RS17070	COG0066	3-isopropylmalate dehydratase activity
BKP57_RS17075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKP57_RS17080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_RS17090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKP57_RS17095	COG0366	Alpha amylase catalytic
BKP57_RS17100	COG1917	Cupin 2, conserved barrel domain protein
BKP57_RS17100	COG2207	Transcriptional regulator
BKP57_RS17115	COG0395	ABC-type sugar transport system, permease component
BKP57_RS17120	COG5426	von Willebrand factor, type A
BKP57_RS17125	COG1940	carbohydrate kinase activity
BKP57_RS17130	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKP57_RS17140	COG1476	TRANSCRIPTIONal
BKP57_RS17160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP57_RS17165	COG2076	Multidrug Resistance protein
BKP57_RS17175	COG0463	Glycosyl transferase, family 2
BKP57_RS17195	COG4608	Belongs to the ABC transporter superfamily
BKP57_RS17200	COG0601	transmembrane transport
BKP57_RS17215	COG0367	asparagine synthase
BKP57_RS17225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKP57_RS17230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKP57_RS17235	COG2376	Dihydroxyacetone kinase
BKP57_RS17240	COG1461	Dihydroxyacetone kinase
BKP57_RS17245	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BKP57_RS17255	COG1966	Carbon starvation protein
BKP57_RS17260	COG3279	Response regulator of the LytR AlgR family
BKP57_RS17265	COG3275	phosphorelay sensor kinase activity
BKP57_RS17270	COG1522	sequence-specific DNA binding
BKP57_RS17280	COG2059	Chromate
BKP57_RS17285	COG2059	Chromate
BKP57_RS17290	COG0561	phosphatase activity
BKP57_RS17295	COG0745	RESPONSE REGULATOR receiver
BKP57_RS17305	COG2996	Protein conserved in bacteria
BKP57_RS17310	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS17315	COG1971	Probably functions as a manganese efflux pump
BKP57_RS17340	COG1473	amidohydrolase
BKP57_RS17410	COG2226	methyltransferase
BKP57_RS17430	COG1331	Highly conserved protein containing a thioredoxin domain
BKP57_RS17435	COG1595	DNA-templated transcription, initiation
BKP57_RS17465	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS17470	COG3639	organic phosphonate transmembrane transporter activity
BKP57_RS17475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKP57_RS17485	COG0788	formyltetrahydrofolate deformylase activity
BKP57_RS17495	COG2391	methyltransferase activity
BKP57_RS17540	COG2182	Extracellular solute-binding protein
BKP57_RS17545	COG1175	transmembrane transport
BKP57_RS17550	COG3833	ABC-type maltose transport systems, permease component
BKP57_RS17560	COG1609	Transcriptional regulator
BKP57_RS17565	COG1486	melibiose metabolic process
BKP57_RS17585	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_RS17595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKP57_RS17600	COG2971	BadF BadG BcrA BcrD
BKP57_RS17610	COG1472	Belongs to the glycosyl hydrolase 3 family
BKP57_RS17615	COG1653	transport
BKP57_RS17620	COG1175	transmembrane transport
BKP57_RS17625	COG0395	ABC-type sugar transport system, permease component
BKP57_RS17670	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS17675	COG0840	transmembrane signaling receptor activity
BKP57_RS17680	COG0840	transmembrane signaling receptor activity
BKP57_RS17685	COG1368	sulfuric ester hydrolase activity
BKP57_RS17700	COG2807	transmembrane transport
BKP57_RS17705	COG2814	Major facilitator Superfamily
BKP57_RS17710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKP57_RS17715	COG0471	metal ion transport
BKP57_RS17720	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKP57_RS17725	COG2814	Major facilitator Superfamily
BKP57_RS17730	COG0561	phosphatase activity
BKP57_RS17740	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS17750	COG0768	penicillin binding
BKP57_RS17755	COG1316	TRANSCRIPTIONal
BKP57_RS17775	COG0681	Belongs to the peptidase S26 family
BKP57_RS17795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKP57_RS17800	COG0363	glucosamine-6-phosphate deaminase activity
BKP57_RS17805	COG1739	Uncharacterized protein family UPF0029
BKP57_RS17815	COG2197	response regulator
BKP57_RS17820	COG1307	EDD domain protein, DegV family
BKP57_RS17825	COG2197	response regulator
BKP57_RS17835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKP57_RS17840	COG1040	competence protein
BKP57_RS17860	COG1256	bacterial-type flagellum assembly
BKP57_RS17860	COG4786	Flagellar basal body rod
BKP57_RS17865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP57_RS17875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKP57_RS17880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BKP57_RS17885	COG1334	flagellar protein FlaG
BKP57_RS17890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKP57_RS17895	COG1516	flagellar protein fliS
BKP57_RS17905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKP57_RS17910	COG0653	protein targeting
BKP57_RS17915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKP57_RS17925	COG2884	Cell division ATP-binding protein ftsE
BKP57_RS17930	COG2177	Part of the ABC transporter FtsEX involved in
BKP57_RS17935	COG0739	heme binding
BKP57_RS17940	COG0793	Belongs to the peptidase S41A family
BKP57_RS17940	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_RS17950	COG0726	polysaccharide deacetylase
BKP57_RS17955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP57_RS17960	COG0556	nucleotide-excision repair
BKP57_RS17965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKP57_RS17970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP57_RS17975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP57_RS17980	COG1983	PspC domain protein
BKP57_RS17985	COG1950	PFAM Membrane protein of
BKP57_RS17990	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKP57_RS17995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKP57_RS18000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_RS18005	COG0546	phosphoglycolate phosphatase activity
BKP57_RS18010	COG0110	maltose O-acetyltransferase activity
BKP57_RS18015	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BKP57_RS18020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKP57_RS18025	COG0457	Tetratricopeptide repeat
BKP57_RS18030	COG0492	ferredoxin-NADP+ reductase activity
BKP57_RS18035	COG1051	belongs to the nudix hydrolase family
BKP57_RS18040	COG1660	Displays ATPase and GTPase activities
BKP57_RS18045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKP57_RS18050	COG1481	regulation of sporulation
BKP57_RS18055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS18060	COG0740	serine-type endopeptidase activity
BKP57_RS18070	COG4974	Belongs to the 'phage' integrase family
BKP57_RS18080	COG0582	viral genome integration into host DNA
BKP57_RS18180	COG1914	H( )-stimulated, divalent metal cation uptake system
BKP57_RS18185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKP57_RS18190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKP57_RS18195	COG1984	allophanate hydrolase subunit 2
BKP57_RS18220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKP57_RS18225	COG0710	3-dehydroquinate dehydratase activity
BKP57_RS18235	COG2112	serine threonine protein kinase
BKP57_RS18240	COG0328	RNA-DNA hybrid ribonuclease activity
BKP57_RS18245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKP57_RS18265	COG0126	phosphoglycerate kinase activity
BKP57_RS18270	COG0149	triose-phosphate isomerase activity
BKP57_RS18275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKP57_RS18280	COG0148	phosphopyruvate hydratase activity
BKP57_RS18285	COG1484	DNA-dependent DNA replication
BKP57_RS18305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP57_RS18315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP57_RS18320	COG1116	anion transmembrane transporter activity
BKP57_RS18325	COG0084	hydrolase, TatD family'
BKP57_RS18345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP57_RS18350	COG1647	Serine aminopeptidase, S33
BKP57_RS18355	COG0557	exoribonuclease II activity
BKP57_RS18360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKP57_RS18380	COG0517	IMP dehydrogenase activity
BKP57_RS18385	COG1272	protein, Hemolysin III
BKP57_RS18395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_RS18400	COG0586	Pfam SNARE associated Golgi protein
BKP57_RS18420	COG4758	membrane
BKP57_RS18425	COG4585	Histidine kinase
BKP57_RS18430	COG2197	response regulator
BKP57_RS18435	COG4129	membrane
BKP57_RS18440	COG2224	Isocitrate lyase
BKP57_RS18445	COG3883	PFAM NLP P60 protein
BKP57_RS18445	COG0791	NLP P60 protein
BKP57_RS18460	COG2076	Multidrug Resistance protein
BKP57_RS18465	COG2076	Multidrug Resistance protein
BKP57_RS18480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP57_RS18485	COG0735	belongs to the Fur family
BKP57_RS18490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_RS18495	COG1121	(ABC) transporter
BKP57_RS18505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_RS18510	COG0431	NADPH-dependent FMN reductase
BKP57_RS18515	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_RS18515	COG1024	Enoyl-CoA hydratase
BKP57_RS18520	COG0183	Belongs to the thiolase family
BKP57_RS18525	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS18530	COG1393	Belongs to the ArsC family
BKP57_RS18535	COG0509	glycine decarboxylation via glycine cleavage system
BKP57_RS18540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKP57_RS18545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS18550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKP57_RS18555	COG2011	ABC-type metal ion transport system permease component
BKP57_RS18560	COG1464	Belongs to the NlpA lipoprotein family
BKP57_RS18565	COG0396	ATPase activity
BKP57_RS18570	COG0719	Fe-S assembly protein
BKP57_RS18575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKP57_RS18580	COG0822	iron-sulfur transferase activity
BKP57_RS18585	COG0719	Fe-S assembly protein
BKP57_RS18595	COG2076	Multidrug Resistance protein
BKP57_RS18620	COG3284	Transcriptional regulator
BKP57_RS18625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP57_RS18630	COG0022	dehydrogenase e1 component
BKP57_RS18635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_RS18645	COG3227	Zinc metalloprotease (Elastase)
BKP57_RS18650	COG1063	alcohol dehydrogenase
BKP57_RS18685	COG0745	RESPONSE REGULATOR receiver
BKP57_RS18690	COG3850	Histidine kinase
BKP57_RS18690	COG5002	protein histidine kinase activity
BKP57_RS18700	COG0501	Belongs to the peptidase M48B family
BKP57_RS18710	COG1295	ribonuclease BN
BKP57_RS18740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKP57_RS18745	COG1368	sulfuric ester hydrolase activity
BKP57_RS18755	COG0431	NADPH-dependent FMN reductase
BKP57_RS18760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_RS18785	COG0204	Acyl-transferase
BKP57_RS18790	COG0477	Major facilitator Superfamily
BKP57_RS18795	COG0583	DNA-binding transcription factor activity
BKP57_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_RS18820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_RS18845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP57_RS18860	COG2329	Antibiotic biosynthesis monooxygenase
BKP57_RS18865	COG2202	Pas domain
BKP57_RS18865	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_RS18870	COG3425	synthase
BKP57_RS18880	COG1131	(ABC) transporter
BKP57_RS18905	COG1228	amidohydrolase
BKP57_RS18925	COG2076	Multidrug Resistance protein
BKP57_RS18940	COG1408	metallophosphoesterase
BKP57_RS18950	COG5564	TIM-barrel signal transduction protein
BKP57_RS18960	COG5564	TIM-barrel signal transduction protein
BKP57_RS18970	COG1533	DNA photolyase activity
BKP57_RS19005	COG2391	methyltransferase activity
BKP57_RS19015	COG1349	DNA-binding transcription factor activity
BKP57_RS19025	COG2268	Band 7 protein
BKP57_RS19030	COG1585	Membrane protein implicated in regulation of membrane protease activity
BKP57_RS19035	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_RS19040	COG3842	ATPase activity
BKP57_RS19045	COG1175	transmembrane transport
BKP57_RS19060	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_RS19065	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_RS19190	COG1063	alcohol dehydrogenase
BKP57_RS19200	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP57_RS19210	COG1301	dicarboxylic acid transport
BKP57_RS19215	COG2814	Major facilitator Superfamily
BKP57_RS19220	COG5504	Zn-dependent protease
BKP57_RS19225	COG2226	methyltransferase
BKP57_RS19245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_RS19255	COG0420	3'-5' exonuclease activity
BKP57_RS19260	COG0419	ATPase involved in DNA repair
BKP57_RS19265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_RS19270	COG2188	Transcriptional regulator
BKP57_RS19290	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_RS19295	COG0626	cystathionine gamma-synthase activity
BKP57_RS19305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKP57_RS19310	COG0667	Aldo Keto reductase
BKP57_RS19315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_RS19320	COG2027	D-alanyl-D-alanine carboxypeptidase
BKP57_RS19325	COG0358	DNA primase activity
BKP57_RS19345	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS19350	COG1252	NADH dehydrogenase
BKP57_RS19355	COG2720	vancomycin resistance protein
BKP57_RS19360	COG2353	YceI-like domain
BKP57_RS19370	COG3069	C4-dicarboxylate transmembrane transporter activity
BKP57_RS19385	COG0003	Pfam Anion-transporting ATPase
BKP57_RS19390	COG0604	alcohol dehydrogenase
BKP57_RS19395	COG1301	dicarboxylic acid transport
BKP57_RS19400	COG2323	membrane
BKP57_RS19415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_RS19440	COG0778	Nitroreductase
BKP57_RS19450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP57_RS19455	COG5001	Diguanylate cyclase
BKP57_RS19455	COG3300	MHYT domain
BKP57_RS19465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_RS19485	COG0436	Aminotransferase
BKP57_RS19495	COG2962	Rard protein
BKP57_RS19510	COG1408	metallophosphoesterase
BKP57_RS19520	COG0640	Transcriptional regulator
BKP57_RS19525	COG0517	IMP dehydrogenase activity
BKP57_RS19530	COG2171	N-acyltransferase activity
BKP57_RS19535	COG1473	amidohydrolase
BKP57_RS19545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS19550	COG1132	(ABC) transporter
BKP57_RS19555	COG1132	(ABC) transporter
BKP57_RS19560	COG0569	domain protein
BKP57_RS19565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKP57_RS19575	COG0561	phosphatase activity
BKP57_RS19580	COG0242	peptide deformylase activity
BKP57_RS19595	COG0022	dehydrogenase e1 component
BKP57_RS19615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP57_RS19630	COG4476	Belongs to the UPF0223 family
BKP57_RS19635	COG4493	Belongs to the UPF0637 family
BKP57_RS19645	COG0483	inositol monophosphate 1-phosphatase activity
BKP57_RS19670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKP57_RS19675	COG4838	Belongs to the UPF0358 family
BKP57_RS19680	COG0772	Belongs to the SEDS family
BKP57_RS19685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKP57_RS19690	COG1612	heme a metabolic process
BKP57_RS19695	COG0109	protoheme IX farnesyltransferase activity
BKP57_RS19700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_RS19700	COG2010	Cytochrome c
BKP57_RS19710	COG1845	cytochrome c oxidase, subunit III
BKP57_RS19720	COG3336	cytochrome c oxidase
BKP57_RS19740	COG2340	Cysteine-rich secretory protein family
BKP57_RS19755	COG3679	Belongs to the UPF0342 family
BKP57_RS19760	COG4471	UPF0298 protein
BKP57_RS19765	COG0742	ribosomal rna small subunit methyltransferase
BKP57_RS19770	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKP57_RS19775	COG3314	Sporulation integral membrane protein YlbJ
BKP57_RS19780	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKP57_RS19785	COG1323	Belongs to the UPF0348 family
BKP57_RS19790	COG1399	metal-binding, possibly nucleic acid-binding protein
BKP57_RS19795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKP57_RS19805	COG0454	-acetyltransferase
BKP57_RS19815	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BKP57_RS19820	COG2001	Belongs to the MraZ family
BKP57_RS19825	COG0275	rRNA processing
BKP57_RS19830	COG4839	cell division protein FtsL
BKP57_RS19835	COG0768	penicillin binding
BKP57_RS19840	COG0768	penicillin binding
BKP57_RS19845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKP57_RS19850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKP57_RS19855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_RS19860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKP57_RS19865	COG0772	Belongs to the SEDS family
BKP57_RS19870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKP57_RS19875	COG0849	cell division
BKP57_RS19880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKP57_RS19885	COG3344	reverse transcriptase
BKP57_RS19895	COG1191	sigma factor activity
BKP57_RS19900	COG1191	sigma factor activity
BKP57_RS19905	COG1873	PFAM PRC-barrel domain
BKP57_RS19910	COG1496	oxidoreductase activity
BKP57_RS19915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKP57_RS19920	COG1799	cell septum assembly
BKP57_RS19925	COG0762	integral membrane protein
BKP57_RS19930	COG2302	S4 RNA-binding domain
BKP57_RS19935	COG3599	regulation of cell shape
BKP57_RS19940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKP57_RS19945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKP57_RS19950	COG0564	pseudouridine synthase activity
BKP57_RS19955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKP57_RS19960	COG0540	Belongs to the ATCase OTCase family
BKP57_RS19965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKP57_RS19970	COG0505	Belongs to the CarA family
BKP57_RS19980	COG0543	2 iron, 2 sulfur cluster binding
BKP57_RS19985	COG0167	dihydroorotate dehydrogenase activity
BKP57_RS19990	COG0284	orotidine-5'-phosphate decarboxylase activity
BKP57_RS19995	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKP57_RS20000	COG2226	methyltransferase
BKP57_RS20005	COG0583	DNA-binding transcription factor activity
BKP57_RS20010	COG1764	response to oxidative stress
BKP57_RS20020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP57_RS20025	COG1561	YicC-like family, N-terminal region
BKP57_RS20030	COG2052	Domain of unknown function (DUF370)
BKP57_RS20035	COG0194	GDP metabolic process
BKP57_RS20040	COG1758	RNA polymerase activity
BKP57_RS20045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP57_RS20050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKP57_RS20055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKP57_RS20060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKP57_RS20060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP57_RS20065	COG0631	protein serine/threonine phosphatase activity
BKP57_RS20070	COG2815	serine threonine protein kinase
BKP57_RS20070	COG0515	serine threonine protein kinase
BKP57_RS20075	COG1162	GTPase activity
BKP57_RS20080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKP57_RS20085	COG1564	THIamine pyrophosphokinase
BKP57_RS20095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKP57_RS20110	COG1302	Protein conserved in bacteria
BKP57_RS20115	COG1461	Dihydroxyacetone kinase
BKP57_RS20125	COG1760	l-serine dehydratase
BKP57_RS20130	COG1760	l-serine dehydratase
BKP57_RS20135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKP57_RS20140	COG1349	DNA-binding transcription factor activity
BKP57_RS20145	COG0416	fatty acid biosynthetic process
BKP57_RS20150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKP57_RS20155	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_RS20160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP57_RS20165	COG0571	ribonuclease III activity
BKP57_RS20170	COG4840	Belongs to the UPF0435 family
BKP57_RS20175	COG1196	nuclear chromosome segregation
BKP57_RS20180	COG0552	protein localization to endoplasmic reticulum
BKP57_RS20185	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BKP57_RS20190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKP57_RS20195	COG0228	four-way junction DNA binding
BKP57_RS20200	COG1837	Belongs to the UPF0109 family
BKP57_RS20210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKP57_RS20215	COG0336	Belongs to the RNA methyltransferase TrmD family
BKP57_RS20220	COG0335	large ribosomal subunit rRNA binding
BKP57_RS20230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP57_RS20235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP57_RS20245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_RS20250	COG0045	succinate-CoA ligase (ADP-forming) activity
BKP57_RS20255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKP57_RS20260	COG0758	DNA mediated transformation
BKP57_RS20265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP57_RS20270	COG4974	Belongs to the 'phage' integrase family
BKP57_RS20275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKP57_RS20280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKP57_RS20285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKP57_RS20290	COG1815	bacterial-type flagellum-dependent cell motility
BKP57_RS20295	COG1558	bacterial-type flagellum-dependent cell motility
BKP57_RS20300	COG1677	Flagellar hook-basal body complex protein FliE
BKP57_RS20305	COG1766	The M ring may be actively involved in energy transduction
BKP57_RS20310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_RS20320	COG1157	protein secretion by the type III secretion system
BKP57_RS20335	COG3144	bacterial-type flagellum assembly
BKP57_RS20340	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKP57_RS20345	COG4786	Flagellar basal body rod
BKP57_RS20350	COG1582	Flagellar protein (FlbD)
BKP57_RS20355	COG1580	Controls the rotational direction of flagella during chemotaxis
BKP57_RS20360	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_RS20365	COG1776	CheC inhibitor of MCP methylation
BKP57_RS20365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_RS20370	COG2201	protein-glutamate methylesterase activity
BKP57_RS20375	COG3190	flagellar
BKP57_RS20380	COG1338	Plays a role in the flagellum-specific transport system
BKP57_RS20385	COG1987	bacterial-type flagellum assembly
BKP57_RS20390	COG1684	flagellar biosynthetic protein fliR
BKP57_RS20395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_RS20400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_RS20405	COG1419	protein localization to endoplasmic reticulum
BKP57_RS20410	COG0455	bacterial-type flagellum organization
BKP57_RS20415	COG2201	protein-glutamate methylesterase activity
BKP57_RS20420	COG2198	Histidine kinase
BKP57_RS20420	COG0643	Histidine kinase
BKP57_RS20425	COG0835	chemotaxis
BKP57_RS20430	COG1776	CheC inhibitor of MCP methylation
BKP57_RS20435	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKP57_RS20440	COG1191	sigma factor activity
BKP57_RS20460	COG0052	Belongs to the universal ribosomal protein uS2 family
BKP57_RS20465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKP57_RS20470	COG0528	UMP kinase activity
BKP57_RS20475	COG0233	cytoplasmic translational termination
BKP57_RS20480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKP57_RS20485	COG4589	Belongs to the CDS family
BKP57_RS20490	COG0750	zinc metalloprotease
BKP57_RS20495	COG2176	DNA-directed DNA polymerase activity
BKP57_RS20500	COG0779	Required for maturation of 30S ribosomal subunits
BKP57_RS20505	COG0195	Participates in both transcription termination and antitermination
BKP57_RS20510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BKP57_RS20520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKP57_RS20525	COG1550	Protein conserved in bacteria
BKP57_RS20530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKP57_RS20535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKP57_RS20540	COG0196	riboflavin kinase activity
BKP57_RS20545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKP57_RS20550	COG1185	polyribonucleotide nucleotidyltransferase activity
BKP57_RS20555	COG0726	polysaccharide deacetylase
BKP57_RS20560	COG0612	Peptidase, M16
BKP57_RS20565	COG1873	PFAM PRC-barrel domain
BKP57_RS20570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_RS20575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP57_RS20580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKP57_RS20585	COG0527	aspartate kinase activity
BKP57_RS20590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_RS20595	COG0740	serine-type endopeptidase activity
BKP57_RS20605	COG1674	ftsk spoiiie
BKP57_RS20610	COG2188	Transcriptional regulator
BKP57_RS20615	COG1744	ABC transporter substrate-binding protein PnrA-like
BKP57_RS20620	COG3845	ABC transporter
BKP57_RS20625	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKP57_RS20630	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKP57_RS20635	COG0612	Peptidase, M16
BKP57_RS20640	COG0612	Peptidase, M16
BKP57_RS20645	COG0300	oxidoreductase activity
BKP57_RS20660	COG1426	Protein conserved in bacteria
BKP57_RS20665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKP57_RS20670	COG1058	Belongs to the CinA family
BKP57_RS20670	COG1546	Belongs to the CinA family
BKP57_RS20675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKP57_RS20685	COG1418	mRNA catabolic process
BKP57_RS20690	COG1692	metallophosphoesterase
BKP57_RS20695	COG2359	stage V sporulation protein S
BKP57_RS20700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP57_RS20705	COG4550	Control of competence regulator ComK, YlbF/YmcA
BKP57_RS20715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKP57_RS20720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKP57_RS20725	COG0783	Belongs to the Dps family
BKP57_RS20730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKP57_RS20735	COG1923	regulation of RNA biosynthetic process
BKP57_RS20740	COG0464	growth
BKP57_RS20745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKP57_RS20750	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BKP57_RS20775	COG0789	Transcriptional regulator
BKP57_RS20780	COG0174	glutamine synthetase
BKP57_RS20790	COG3152	Membrane
BKP57_RS20815	COG3546	catalase activity
BKP57_RS20825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKP57_RS20865	COG5377	YqaJ viral recombinase family
BKP57_RS20945	COG4824	toxin secretion phage lysis holin
BKP57_RS20975	COG3546	catalase activity
BKP57_RS20995	COG3546	catalase activity
BKP57_RS21030	COG3546	catalase activity
BKP57_RS21035	COG3546	catalase activity
BKP57_RS21040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKP57_RS21045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKP57_RS21050	COG4224	UPF0291 protein
BKP57_RS21065	COG3763	UPF0154 protein
BKP57_RS21070	COG0785	Cytochrome C biogenesis protein
BKP57_RS21075	COG2111	Na H antiporter
BKP57_RS21080	COG2201	protein-glutamate methylesterase activity
BKP57_RS21085	COG4846	Membrane protein involved in cytochrome C biogenesis
BKP57_RS21100	COG4191	Histidine kinase
BKP57_RS21105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKP57_RS21110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_RS21125	COG0824	Thioesterase
BKP57_RS21140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKP57_RS21145	COG1469	GTP cyclohydrolase I activity
BKP57_RS21150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP57_RS21165	COG1832	CoA-binding protein
BKP57_RS21170	COG0187	DNA topoisomerase II activity
BKP57_RS21175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP57_RS21185	COG1960	acyl-CoA dehydrogenase activity
BKP57_RS21190	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_RS21195	COG0439	Biotin carboxylase
BKP57_RS21200	COG0511	ligase activity, forming carbon-carbon bonds
BKP57_RS21205	COG1024	Enoyl-CoA hydratase
BKP57_RS21210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_RS21215	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP57_RS21220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_RS21225	COG1126	abc transporter atp-binding protein
BKP57_RS21230	COG0390	transport system, permease component
BKP57_RS21240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_RS21270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_RS21275	COG0789	Transcriptional regulator
BKP57_RS21290	COG0346	lactoylglutathione lyase activity
BKP57_RS21345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_RS21385	COG4974	Belongs to the 'phage' integrase family
BKP57_RS21390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_RS21390	COG0723	plastoquinol--plastocyanin reductase activity
BKP57_RS21395	COG1254	Belongs to the acylphosphatase family
BKP57_RS21435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_RS21435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_RS21455	COG4479	Belongs to the UPF0346 family
BKP57_RS21460	COG0805	protein transport
BKP57_RS21465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP57_RS21475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKP57_RS21480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKP57_RS21485	COG1388	LysM domain
BKP57_RS21485	COG0791	NLP P60 protein
BKP57_RS21495	COG1418	mRNA catabolic process
BKP57_RS21510	COG0659	secondary active sulfate transmembrane transporter activity
BKP57_RS21515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKP57_RS21525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_RS21530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP57_RS21535	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKP57_RS21540	COG3424	synthase
BKP57_RS21545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BKP57_RS21550	COG0116	Belongs to the methyltransferase superfamily