locus-tag	class	description
D9782_RS00010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS00010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS00010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS00015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS00015	COG3711	transcriptional antiterminator
D9782_RS00020	COG3711	transcriptional antiterminator
D9782_RS00020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS00025	COG2723	6-phospho-beta-galactosidase activity
D9782_RS00030	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9782_RS00035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS00040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS00070	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS00075	COG2333	competence protein COMEC
D9782_RS00075	COG0658	competence protein
D9782_RS00085	COG3876	Protein conserved in bacteria
D9782_RS00090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS00100	COG1486	melibiose metabolic process
D9782_RS00105	COG1263	PTS System
D9782_RS00105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9782_RS00105	COG2190	(PTS) system
D9782_RS00110	COG3711	transcriptional antiterminator
D9782_RS00115	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9782_RS00120	COG4948	Mandelate Racemase Muconate Lactonizing
D9782_RS00125	COG1288	antiporter activity
D9782_RS00135	COG1473	amidohydrolase
D9782_RS00155	COG1595	DNA-templated transcription, initiation
D9782_RS00180	COG5146	pantothenate kinase activity
D9782_RS00185	COG1846	Transcriptional regulator
D9782_RS00190	COG2814	Major facilitator Superfamily
D9782_RS00195	COG1288	antiporter activity
D9782_RS00230	COG4821	SIS domain
D9782_RS00240	COG1735	metal-dependent hydrolase with the TIM-barrel fold
D9782_RS00250	COG3414	Phosphotransferase system galactitol-specific IIB component
D9782_RS00260	COG3711	transcriptional antiterminator
D9782_RS00270	COG2706	6-phosphogluconolactonase activity
D9782_RS00275	COG1309	transcriptional regulator
D9782_RS00285	COG0506	proline dehydrogenase activity
D9782_RS00290	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS00295	COG1396	sequence-specific DNA binding
D9782_RS00295	COG3800	Transcriptional regulator
D9782_RS00305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9782_RS00320	COG1757	Na H antiporter
D9782_RS00325	COG0366	Alpha amylase catalytic
D9782_RS00335	COG2190	(PTS) system
D9782_RS00335	COG1263	PTS System
D9782_RS00335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9782_RS00345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9782_RS00350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9782_RS00380	COG1024	Enoyl-CoA hydratase
D9782_RS00390	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS00395	COG2084	Dehydrogenase
D9782_RS00400	COG1960	acyl-CoA dehydrogenase activity
D9782_RS00405	COG3290	protein histidine kinase activity
D9782_RS00405	COG3829	transcription factor binding
D9782_RS00415	COG0786	glutamate:sodium symporter activity
D9782_RS00420	COG0010	Belongs to the arginase family
D9782_RS00440	COG2070	2-Nitropropane dioxygenase
D9782_RS00445	COG2986	histidine ammonia-lyase
D9782_RS00455	COG1228	amidohydrolase
D9782_RS00460	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D9782_RS00465	COG0583	DNA-binding transcription factor activity
D9782_RS00470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9782_RS00485	COG1063	alcohol dehydrogenase
D9782_RS00515	COG1876	peptidase activity
D9782_RS00595	COG0740	serine-type endopeptidase activity
D9782_RS00645	COG2226	methyltransferase
D9782_RS00680	COG0305	Participates in initiation and elongation during chromosome replication
D9782_RS00695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9782_RS00770	COG1396	sequence-specific DNA binding
D9782_RS00780	COG4974	Belongs to the 'phage' integrase family
D9782_RS00790	COG2368	4-hydroxyphenylacetate
D9782_RS00800	COG2124	cytochrome p450
D9782_RS00805	COG0300	oxidoreductase activity
D9782_RS00810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9782_RS00815	COG2022	thiamine diphosphate biosynthetic process
D9782_RS00830	COG0352	thiamine-phosphate diphosphorylase activity
D9782_RS00835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9782_RS00840	COG2801	Transposase and inactivated derivatives
D9782_RS00845	COG0402	S-adenosylhomocysteine deaminase activity
D9782_RS00850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9782_RS00870	COG4948	Mandelate Racemase Muconate Lactonizing
D9782_RS00895	COG2197	response regulator
D9782_RS00900	COG0791	NLP P60 protein
D9782_RS00900	COG1388	LysM domain
D9782_RS00905	COG3964	amidohydrolase
D9782_RS00935	COG0395	ABC-type sugar transport system, permease component
D9782_RS00940	COG4209	transmembrane transport
D9782_RS00945	COG3397	chitin binding
D9782_RS00955	COG2706	6-phosphogluconolactonase activity
D9782_RS00965	COG0395	ABC-type sugar transport system, permease component
D9782_RS00970	COG1175	transmembrane transport
D9782_RS00980	COG2188	Transcriptional regulator
D9782_RS00985	COG0432	Pfam Uncharacterised protein family UPF0047
D9782_RS00995	COG0436	Aminotransferase
D9782_RS01010	COG0673	inositol 2-dehydrogenase activity
D9782_RS01030	COG0673	inositol 2-dehydrogenase activity
D9782_RS01045	COG1653	transport
D9782_RS01050	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS01055	COG1609	Transcriptional regulator
D9782_RS01060	COG1595	DNA-templated transcription, initiation
D9782_RS01070	COG2755	lipolytic protein G-D-S-L family
D9782_RS01070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D9782_RS01075	COG0662	Cupin 2, conserved barrel domain protein
D9782_RS01100	COG3716	PTS system mannose fructose sorbose family IID component
D9782_RS01105	COG3715	PTS system
D9782_RS01110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9782_RS01115	COG2222	sugar isomerase
D9782_RS01120	COG2188	Transcriptional regulator
D9782_RS01125	COG1609	Transcriptional regulator
D9782_RS01140	COG0395	ABC-type sugar transport system, permease component
D9782_RS01145	COG1175	transmembrane transport
D9782_RS01155	COG1940	carbohydrate kinase activity
D9782_RS01165	COG3250	beta-galactosidase activity
D9782_RS01180	COG0395	ABC-type sugar transport system, permease component
D9782_RS01190	COG1653	transport
D9782_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS01200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9782_RS01205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9782_RS01210	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9782_RS01215	COG2017	converts alpha-aldose to the beta-anomer
D9782_RS01255	COG0673	inositol 2-dehydrogenase activity
D9782_RS01275	COG0383	alpha-mannosidase activity
D9782_RS01285	COG2182	Extracellular solute-binding protein
D9782_RS01290	COG0395	ABC-type sugar transport system, permease component
D9782_RS01295	COG4209	transmembrane transport
D9782_RS01310	COG0519	Catalyzes the synthesis of GMP from XMP
D9782_RS01315	COG2205	protein histidine kinase activity
D9782_RS01320	COG0745	RESPONSE REGULATOR receiver
D9782_RS01325	COG0577	efflux transmembrane transporter activity
D9782_RS01330	COG1136	(ABC) transporter
D9782_RS01350	COG0561	phosphatase activity
D9782_RS01355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS01360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS01365	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9782_RS01425	COG3433	isochorismatase activity
D9782_RS01425	COG1535	isochorismatase
D9782_RS01445	COG0135	phosphoribosylanthranilate isomerase activity
D9782_RS01455	COG2211	Major facilitator Superfamily
D9782_RS01470	COG2207	Transcriptional regulator
D9782_RS01475	COG5578	integral membrane protein
D9782_RS01510	COG1609	Transcriptional regulator
D9782_RS01515	COG2807	transmembrane transport
D9782_RS01520	COG1316	TRANSCRIPTIONal
D9782_RS01530	COG1316	TRANSCRIPTIONal
D9782_RS01535	COG3385	transposase activity
D9782_RS01545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9782_RS01560	COG1216	Glycosyl transferase, family 2
D9782_RS01590	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS01595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9782_RS01600	COG1134	teichoic acid transport
D9782_RS01605	COG1682	transport, permease protein
D9782_RS01610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS01615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS01625	COG2801	Transposase and inactivated derivatives
D9782_RS01650	COG4193	domain, Protein
D9782_RS01660	COG0438	transferase activity, transferring glycosyl groups
D9782_RS01665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS01675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9782_RS01680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS01685	COG4193	domain, Protein
D9782_RS01690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9782_RS01695	COG2244	polysaccharide biosynthetic process
D9782_RS01715	COG2076	Multidrug Resistance protein
D9782_RS01725	COG0463	Glycosyl transferase, family 2
D9782_RS01735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9782_RS01740	COG0584	glycerophosphoryl diester phosphodiesterase
D9782_RS01745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9782_RS01750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS01755	COG0531	amino acid
D9782_RS01775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9782_RS01790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9782_RS01795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9782_RS01805	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9782_RS01810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9782_RS01815	COG0095	Lipoate-protein ligase
D9782_RS01825	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9782_RS01830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9782_RS01835	COG1486	melibiose metabolic process
D9782_RS01840	COG2188	Transcriptional regulator
D9782_RS01845	COG3394	polysaccharide catabolic process
D9782_RS01860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9782_RS01870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9782_RS01875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9782_RS01880	COG1309	transcriptional regulator
D9782_RS01910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9782_RS01925	COG4786	Flagellar basal body rod
D9782_RS01930	COG4786	Flagellar basal body rod
D9782_RS01935	COG1077	Cell shape determining protein MreB Mrl
D9782_RS01940	COG1609	Transcriptional regulator
D9782_RS01960	COG2385	sporulation resulting in formation of a cellular spore
D9782_RS01965	COG0456	acetyltransferase
D9782_RS01970	COG4608	Belongs to the ABC transporter superfamily
D9782_RS01975	COG0791	NLP P60 protein
D9782_RS01980	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9782_RS01985	COG4166	transmembrane transport
D9782_RS01990	COG0444	Belongs to the ABC transporter superfamily
D9782_RS01995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS02000	COG0601	transmembrane transport
D9782_RS02005	COG2362	D-Aminopeptidase
D9782_RS02015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9782_RS02030	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9782_RS02035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9782_RS02040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9782_RS02045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9782_RS02050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9782_RS02055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9782_RS02060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9782_RS02065	COG0356	it plays a direct role in the translocation of protons across the membrane
D9782_RS02075	COG1404	Belongs to the peptidase S8 family
D9782_RS02080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9782_RS02085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9782_RS02090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9782_RS02095	COG4475	Protein of unknown function (DUF436)
D9782_RS02100	COG0698	ribose 5-phosphate isomerase
D9782_RS02105	COG0840	transmembrane signaling receptor activity
D9782_RS02110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9782_RS02120	COG1971	Probably functions as a manganese efflux pump
D9782_RS02125	COG0009	L-threonylcarbamoyladenylate synthase
D9782_RS02145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9782_RS02150	COG1435	thymidine kinase activity
D9782_RS02155	COG0254	rRNA binding
D9782_RS02160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9782_RS02165	COG1494	fructose-1,6-bisphosphatase
D9782_RS02170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9782_RS02175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9782_RS02180	COG0191	fructose-bisphosphate aldolase activity
D9782_RS02185	COG2204	response regulator
D9782_RS02205	COG0504	CTP synthase activity
D9782_RS02210	COG3343	RNA polymerase activity
D9782_RS02220	COG1960	acyl-CoA dehydrogenase activity
D9782_RS02225	COG1960	acyl-CoA dehydrogenase activity
D9782_RS02230	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9782_RS02235	COG0183	Belongs to the thiolase family
D9782_RS02240	COG0247	lactate metabolic process
D9782_RS02240	COG2181	nitrate reductase activity
D9782_RS02260	COG0018	arginyl-trna synthetase
D9782_RS02270	COG0010	Belongs to the arginase family
D9782_RS02275	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9782_RS02280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9782_RS02295	COG3465	dGTPase activity
D9782_RS02300	COG1078	dGTPase activity
D9782_RS02305	COG0095	Lipoate-protein ligase
D9782_RS02310	COG0280	phosphate acetyltransferase
D9782_RS02315	COG3253	May function as heme-dependent peroxidase
D9782_RS02320	COG3773	Cell wall hydrolase
D9782_RS02335	COG2363	Small membrane protein
D9782_RS02360	COG3314	Sporulation integral membrane protein YlbJ
D9782_RS02370	COG3594	Acyltransferase
D9782_RS02375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9782_RS02380	COG1793	dna ligase
D9782_RS02380	COG3285	dna ligase
D9782_RS02385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9782_RS02415	COG1764	response to oxidative stress
D9782_RS02420	COG0861	Integral membrane protein TerC family
D9782_RS02425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9782_RS02430	COG0628	permease
D9782_RS02460	COG1114	Component of the transport system for branched-chain amino acids
D9782_RS02465	COG0514	ATP-dependent DNA helicase (RecQ)
D9782_RS02475	COG1733	regulation of RNA biosynthetic process
D9782_RS02480	COG1115	amino acid carrier protein
D9782_RS02485	COG1607	acyl-coa hydrolase
D9782_RS02490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9782_RS02500	COG0626	cystathionine gamma-synthase activity
D9782_RS02505	COG2962	Rard protein
D9782_RS02510	COG2873	o-acetylhomoserine
D9782_RS02515	COG2755	lipolytic protein G-D-S-L family
D9782_RS02530	COG0488	(ABC) transporter
D9782_RS02540	COG2801	Transposase and inactivated derivatives
D9782_RS02545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9782_RS02550	COG0156	8-amino-7-oxononanoate synthase activity
D9782_RS02555	COG2197	response regulator
D9782_RS02560	COG4585	Histidine kinase
D9782_RS02565	COG0842	Transport permease protein
D9782_RS02570	COG1131	(ABC) transporter
D9782_RS02580	COG1388	LysM domain
D9782_RS02580	COG3584	3D domain protein
D9782_RS02590	COG4086	secreted protein
D9782_RS02595	COG2814	Major facilitator Superfamily
D9782_RS02605	COG1979	alcohol dehydrogenase
D9782_RS02610	COG0251	oxidation-reduction process
D9782_RS02615	COG0741	lytic transglycosylase activity
D9782_RS02635	COG4608	Belongs to the ABC transporter superfamily
D9782_RS02640	COG0444	Belongs to the ABC transporter superfamily
D9782_RS02645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS02655	COG4166	transmembrane transport
D9782_RS02675	COG2358	TRAP transporter, solute receptor (TAXI family
D9782_RS02680	COG4608	Belongs to the ABC transporter superfamily
D9782_RS02685	COG0444	Belongs to the ABC transporter superfamily
D9782_RS02690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS02695	COG0601	transmembrane transport
D9782_RS02700	COG4166	transmembrane transport
D9782_RS02730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9782_RS02735	COG1136	(ABC) transporter
D9782_RS02745	COG2814	Major facilitator Superfamily
D9782_RS02750	COG1070	Carbohydrate kinase
D9782_RS02760	COG2032	superoxide dismutase activity
D9782_RS02780	COG1120	ATPase activity
D9782_RS02785	COG4152	abc transporter atp-binding protein
D9782_RS02805	COG0494	nUDIX hydrolase
D9782_RS02810	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9782_RS02820	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS02820	COG3103	Sh3 type 3 domain protein
D9782_RS02820	COG4991	sh3 domain protein
D9782_RS02830	COG2226	methyltransferase
D9782_RS02845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9782_RS02850	COG0716	FMN binding
D9782_RS02855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9782_RS02860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9782_RS02865	COG2323	membrane
D9782_RS02870	COG0367	asparagine synthase
D9782_RS02880	COG1595	DNA-templated transcription, initiation
D9782_RS02885	COG3383	formate dehydrogenase (NAD+) activity
D9782_RS02890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9782_RS02910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9782_RS02915	COG0493	'glutamate synthase
D9782_RS02920	COG0067	glutamate synthase
D9782_RS02920	COG0069	glutamate synthase activity
D9782_RS02920	COG0070	glutamate synthase
D9782_RS02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9782_RS02940	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9782_RS02945	COG0501	Belongs to the peptidase M48B family
D9782_RS02950	COG2197	response regulator
D9782_RS02955	COG4585	Histidine kinase
D9782_RS02960	COG3239	Fatty acid desaturase
D9782_RS02990	COG3279	Response regulator of the LytR AlgR family
D9782_RS03005	COG1252	NADH dehydrogenase
D9782_RS03010	COG1346	cytolysis
D9782_RS03015	COG1380	Effector of murein hydrolase LrgA
D9782_RS03020	COG0165	Argininosuccinate lyase
D9782_RS03025	COG0137	argininosuccinate synthase activity
D9782_RS03030	COG0702	epimerase
D9782_RS03040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9782_RS03045	COG0573	inorganic phosphate transmembrane transporter activity
D9782_RS03050	COG0581	inorganic phosphate transmembrane transporter activity
D9782_RS03055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9782_RS03060	COG0840	transmembrane signaling receptor activity
D9782_RS03070	COG0561	phosphatase activity
D9782_RS03080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS03080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS03085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS03085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS03085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS03100	COG2207	Transcriptional regulator
D9782_RS03100	COG0662	Cupin 2, conserved barrel domain protein
D9782_RS03125	COG0346	lactoylglutathione lyase activity
D9782_RS03145	COG0577	efflux transmembrane transporter activity
D9782_RS03160	COG3871	stress protein (general stress protein 26)
D9782_RS03180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9782_RS03185	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D9782_RS03190	COG0800	Aldolase
D9782_RS03200	COG1609	Transcriptional regulator
D9782_RS03225	COG1929	Belongs to the glycerate kinase type-1 family
D9782_RS03230	COG5294	Protein conserved in bacteria
D9782_RS03235	COG2190	(PTS) system
D9782_RS03240	COG3711	transcriptional antiterminator
D9782_RS03245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9782_RS03245	COG1263	PTS System
D9782_RS03255	COG4326	sporulation control protein
D9782_RS03260	COG1214	PFAM Peptidase M22, glycoprotease
D9782_RS03260	COG0456	acetyltransferase
D9782_RS03275	COG1607	acyl-coa hydrolase
D9782_RS03280	COG0583	DNA-binding transcription factor activity
D9782_RS03295	COG0785	Cytochrome C biogenesis protein
D9782_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS03305	COG0745	RESPONSE REGULATOR receiver
D9782_RS03310	COG5002	protein histidine kinase activity
D9782_RS03320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9782_RS03325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9782_RS03330	COG0640	Transcriptional regulator
D9782_RS03335	COG1937	Protein conserved in bacteria
D9782_RS03340	COG4536	flavin adenine dinucleotide binding
D9782_RS03355	COG3949	Membrane
D9782_RS03360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9782_RS03370	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS03380	COG2719	SpoVR family
D9782_RS03385	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9782_RS03390	COG1121	(ABC) transporter
D9782_RS03395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9782_RS03395	COG1321	iron dependent repressor
D9782_RS03400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9782_RS03420	COG0456	acetyltransferase
D9782_RS03425	COG0693	protein deglycase activity
D9782_RS03435	COG0024	Methionine aminopeptidase
D9782_RS03450	COG2718	Belongs to the UPF0229 family
D9782_RS03455	COG2766	serine protein kinase
D9782_RS03470	COG3639	organic phosphonate transmembrane transporter activity
D9782_RS03475	COG3639	organic phosphonate transmembrane transporter activity
D9782_RS03480	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D9782_RS03490	COG0613	PHP domain protein
D9782_RS03495	COG4778	phosphonate C-P lyase system protein PhnL
D9782_RS03500	COG3454	Phosphonate metabolism
D9782_RS03505	COG4107	phosphonate C-P lyase system protein PhnK
D9782_RS03510	COG3627	carbon phosphorus lyase activity
D9782_RS03530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9782_RS03540	COG0395	ABC-type sugar transport system, permease component
D9782_RS03550	COG3842	ATPase activity
D9782_RS03580	COG0583	DNA-binding transcription factor activity
D9782_RS03585	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9782_RS03595	COG2329	Antibiotic biosynthesis monooxygenase
D9782_RS03600	COG2197	response regulator
D9782_RS03605	COG0745	RESPONSE REGULATOR receiver
D9782_RS03605	COG2972	Histidine kinase
D9782_RS03610	COG3279	Response regulator of the LytR AlgR family
D9782_RS03620	COG0583	DNA-binding transcription factor activity
D9782_RS03670	COG2832	Protein of unknown function (DUF454)
D9782_RS03675	COG4149	molybdate abc transporter
D9782_RS03680	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9782_RS03695	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
D9782_RS03700	COG2223	nitrite transmembrane transporter activity
D9782_RS03710	COG0303	'Molybdopterin
D9782_RS03725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9782_RS03730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9782_RS03735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9782_RS03740	COG2169	Transcriptional regulator
D9782_RS03760	COG0546	phosphoglycolate phosphatase activity
D9782_RS03785	COG0586	Pfam SNARE associated Golgi protein
D9782_RS03790	COG0688	phosphatidylethanolamine metabolic process
D9782_RS03795	COG1183	phosphatidylcholine synthase activity
D9782_RS03805	COG1280	lysine exporter protein (LysE YggA)
D9782_RS03810	COG3403	YqcI/YcgG family
D9782_RS03815	COG1609	Transcriptional regulator
D9782_RS03820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9782_RS03825	COG0561	phosphatase activity
D9782_RS03830	COG0673	inositol 2-dehydrogenase activity
D9782_RS03835	COG0738	Major facilitator superfamily
D9782_RS03840	COG1113	amino acid transport
D9782_RS03850	COG5577	PFAM Coat F domain
D9782_RS03855	COG1278	Cold shock
D9782_RS03860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9782_RS03880	COG2132	Multicopper oxidase
D9782_RS03885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9782_RS03890	COG0579	oxidoreductase
D9782_RS03950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9782_RS03960	COG3949	Membrane
D9782_RS03965	COG2508	Transcriptional regulator
D9782_RS03965	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9782_RS03970	COG0686	Belongs to the AlaDH PNT family
D9782_RS03975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9782_RS03980	COG2723	6-phospho-beta-galactosidase activity
D9782_RS03985	COG3711	transcriptional antiterminator
D9782_RS03995	COG0789	Transcriptional regulator
D9782_RS04010	COG2271	Major facilitator Superfamily
D9782_RS04040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9782_RS04045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9782_RS04050	COG1696	Membrane protein involved in D-alanine export
D9782_RS04055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9782_RS04065	COG0745	RESPONSE REGULATOR receiver
D9782_RS04070	COG5002	protein histidine kinase activity
D9782_RS04110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9782_RS04145	COG3275	phosphorelay sensor kinase activity
D9782_RS04155	COG1966	Carbon starvation protein
D9782_RS04165	COG1522	sequence-specific DNA binding
D9782_RS04185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9782_RS04190	COG2027	D-alanyl-D-alanine carboxypeptidase
D9782_RS04245	COG2318	DinB family
D9782_RS04265	COG3227	Zinc metalloprotease (Elastase)
D9782_RS04270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9782_RS04280	COG0406	alpha-ribazole phosphatase activity
D9782_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS04305	COG0529	Catalyzes the synthesis of activated sulfate
D9782_RS04310	COG3273	potassium ion transport
D9782_RS04310	COG0471	metal ion transport
D9782_RS04315	COG2046	Belongs to the sulfate adenylyltransferase family
D9782_RS04320	COG1587	Uroporphyrinogen-III synthase
D9782_RS04340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9782_RS04345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9782_RS04350	COG0175	sulfate reduction
D9782_RS04360	COG2076	Multidrug Resistance protein
D9782_RS04365	COG1309	transcriptional regulator
D9782_RS04370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS04375	COG0450	alkyl hydroperoxide reductase
D9782_RS04380	COG1132	(ABC) transporter
D9782_RS04395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9782_RS04400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9782_RS04405	COG4853	Protein conserved in bacteria
D9782_RS04410	COG4863	YycH protein
D9782_RS04415	COG5002	protein histidine kinase activity
D9782_RS04420	COG0745	RESPONSE REGULATOR receiver
D9782_RS04430	COG1408	metallophosphoesterase
D9782_RS04435	COG1132	(ABC) transporter
D9782_RS04480	COG0463	Glycosyl transferase, family 2
D9782_RS04485	COG2246	polysaccharide biosynthetic process
D9782_RS04505	COG0572	uridine kinase
D9782_RS04535	COG0438	transferase activity, transferring glycosyl groups
D9782_RS04545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9782_RS04550	COG0110	maltose O-acetyltransferase activity
D9782_RS04565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9782_RS04575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9782_RS04575	COG0463	Glycosyl transferase, family 2
D9782_RS04580	COG0438	transferase activity, transferring glycosyl groups
D9782_RS04585	COG0438	transferase activity, transferring glycosyl groups
D9782_RS04590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9782_RS04595	COG1086	Polysaccharide biosynthesis protein
D9782_RS04600	COG0489	protein tyrosine kinase activity
D9782_RS04605	COG3944	biosynthesis protein
D9782_RS04610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D9782_RS04615	COG0305	Participates in initiation and elongation during chromosome replication
D9782_RS04620	COG0359	binds to the 23S rRNA
D9782_RS04625	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9782_RS04630	COG4241	membrane
D9782_RS04640	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9782_RS04645	COG4149	molybdate abc transporter
D9782_RS04650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D9782_RS04660	COG0668	transmembrane transport
D9782_RS04665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9782_RS04670	COG0629	single-stranded DNA binding
D9782_RS04675	COG0360	Binds together with S18 to 16S ribosomal RNA
D9782_RS04680	COG0012	GTP binding
D9782_RS04685	COG4481	Protein conserved in bacteria
D9782_RS04690	COG0668	transmembrane transport
D9782_RS04695	COG3949	Membrane
D9782_RS04725	COG1475	DNA binding
D9782_RS04730	COG1192	Involved in chromosome partitioning
D9782_RS04735	COG1475	DNA binding
D9782_RS04740	COG0357	Ribosomal RNA small subunit methyltransferase G
D9782_RS04745	COG0445	tRNA wobble uridine modification
D9782_RS04750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9782_RS04755	COG1847	R3H domain protein
D9782_RS04760	COG0706	membrane insertase activity
D9782_RS04765	COG0594	ribonuclease P activity
D9782_RS04770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9782_RS04775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9782_RS04780	COG0592	DNA-directed DNA polymerase activity
D9782_RS04785	COG2501	S4 domain
D9782_RS04790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9782_RS04800	COG0187	DNA topoisomerase II activity
D9782_RS04805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9782_RS04810	COG3437	response regulator, receiver
D9782_RS04820	COG0516	GMP reductase activity
D9782_RS04820	COG0517	IMP dehydrogenase activity
D9782_RS04830	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9782_RS04845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9782_RS04850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS04855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS04860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS04875	COG1595	DNA-templated transcription, initiation
D9782_RS04890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS04895	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS04900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9782_RS04905	COG2011	ABC-type metal ion transport system permease component
D9782_RS04910	COG1464	Belongs to the NlpA lipoprotein family
D9782_RS04925	COG2357	RelA SpoT domain protein
D9782_RS04930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9782_RS04950	COG1428	Deoxynucleoside kinase
D9782_RS04955	COG1428	Deoxynucleoside kinase
D9782_RS04975	COG1309	transcriptional regulator
D9782_RS04980	COG2814	Major facilitator Superfamily
D9782_RS04995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9782_RS05000	COG1268	BioY protein
D9782_RS05005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D9782_RS05010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9782_RS05015	COG1301	dicarboxylic acid transport
D9782_RS05025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9782_RS05035	COG1017	nitric oxide dioxygenase activity
D9782_RS05035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9782_RS05040	COG1959	2 iron, 2 sulfur cluster binding
D9782_RS05055	COG3858	chitin binding
D9782_RS05055	COG1388	LysM domain
D9782_RS05060	COG1335	isochorismatase
D9782_RS05065	COG0590	tRNA wobble adenosine to inosine editing
D9782_RS05080	COG0288	reversible hydration of carbon dioxide
D9782_RS05085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9782_RS05090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9782_RS05095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9782_RS05110	COG1404	Belongs to the peptidase S8 family
D9782_RS05140	COG1982	Orn Lys Arg decarboxylase major
D9782_RS05145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9782_RS05150	COG3870	Protein conserved in bacteria
D9782_RS05155	COG1728	Protein conserved in bacteria
D9782_RS05160	COG0470	DNA polymerase III
D9782_RS05165	COG1774	PSP1 C-terminal conserved region
D9782_RS05170	COG4467	Involved in initiation control of chromosome replication
D9782_RS05175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9782_RS05180	COG2827	Endonuclease containing a URI domain
D9782_RS05185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9782_RS05190	COG2002	toxin-antitoxin pair type II binding
D9782_RS05200	COG0084	hydrolase, TatD family'
D9782_RS05205	COG3584	3D domain protein
D9782_RS05205	COG3583	domain protein
D9782_RS05215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9782_RS05225	COG4466	Protein conserved in bacteria
D9782_RS05235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9782_RS05240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9782_RS05245	COG2088	sporulation resulting in formation of a cellular spore
D9782_RS05250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9782_RS05255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9782_RS05260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9782_RS05265	COG0193	aminoacyl-tRNA hydrolase activity
D9782_RS05275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9782_RS05280	COG2002	toxin-antitoxin pair type II binding
D9782_RS05290	COG2244	polysaccharide biosynthetic process
D9782_RS05295	COG3956	TIGRFAM MazG family protein
D9782_RS05300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9782_RS05320	COG1098	S1 RNA binding domain
D9782_RS05335	COG2208	phosphoserine phosphatase activity
D9782_RS05340	COG2304	oxidoreductase activity
D9782_RS05345	COG0515	serine threonine protein kinase
D9782_RS05350	COG0037	tRNA processing
D9782_RS05355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9782_RS05360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9782_RS05365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9782_RS05370	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9782_RS05380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9782_RS05385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9782_RS05390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9782_RS05395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9782_RS05400	COG1396	sequence-specific DNA binding
D9782_RS05405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9782_RS05485	COG1285	pathogenesis
D9782_RS05495	COG3880	PFAM UvrB UvrC protein
D9782_RS05500	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9782_RS05505	COG0542	response to heat
D9782_RS05510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9782_RS05515	COG4956	integral membrane protein (PIN domain superfamily)
D9782_RS05520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9782_RS05525	COG1045	serine acetyltransferase
D9782_RS05530	COG0215	cysteine-tRNA ligase activity
D9782_RS05540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9782_RS05545	COG3688	RNA-binding protein containing a PIN domain
D9782_RS05555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9782_RS05560	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9782_RS05565	COG0250	Participates in transcription elongation, termination and antitermination
D9782_RS05570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9782_RS05575	COG0081	regulation of translation
D9782_RS05580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9782_RS05585	COG0222	ribosome binding
D9782_RS05590	COG2813	Specifically methylates the guanine in position
D9782_RS05595	COG0085	RNA polymerase activity
D9782_RS05600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9782_RS05605	COG1358	cellular component organization or biogenesis
D9782_RS05610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9782_RS05615	COG0049	tRNA binding
D9782_RS05620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9782_RS05630	COG0051	transcription antitermination factor activity, RNA binding
D9782_RS05635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9782_RS05640	COG0088	Forms part of the polypeptide exit tunnel
D9782_RS05645	COG0089	rRNA binding
D9782_RS05650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9782_RS05655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9782_RS05660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9782_RS05665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9782_RS05670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9782_RS05675	COG0255	Belongs to the universal ribosomal protein uL29 family
D9782_RS05680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9782_RS05685	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9782_RS05690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D9782_RS05695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9782_RS05700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9782_RS05705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9782_RS05710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9782_RS05715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9782_RS05720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9782_RS05725	COG1841	ribosomal large subunit assembly
D9782_RS05730	COG0200	Binds to the 23S rRNA
D9782_RS05735	COG0201	protein transport
D9782_RS05740	COG0563	adenylate kinase activity
D9782_RS05745	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9782_RS05750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9782_RS05755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9782_RS05760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9782_RS05765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9782_RS05770	COG0202	RNA polymerase activity
D9782_RS05775	COG0203	ribosomal protein L17
D9782_RS05780	COG1122	ATPase activity
D9782_RS05785	COG1122	ATPase activity
D9782_RS05790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9782_RS05795	COG0101	tRNA pseudouridine synthase activity
D9782_RS05800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9782_RS05805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9782_RS05855	COG2003	Belongs to the UPF0758 family
D9782_RS05900	COG1131	(ABC) transporter
D9782_RS05905	COG2205	protein histidine kinase activity
D9782_RS05910	COG0745	RESPONSE REGULATOR receiver
D9782_RS05920	COG0702	epimerase
D9782_RS05940	COG2130	NADP-dependent
D9782_RS05950	COG1620	l-lactate permease
D9782_RS05955	COG0039	L-malate dehydrogenase activity
D9782_RS05960	COG0714	Associated with various cellular activities
D9782_RS05965	COG4548	von Willebrand factor, type A
D9782_RS05980	COG0626	cystathionine gamma-synthase activity
D9782_RS05995	COG1295	ribonuclease BN
D9782_RS06020	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS06025	COG0489	protein tyrosine kinase activity
D9782_RS06035	COG2194	sulfuric ester hydrolase activity
D9782_RS06040	COG0726	polysaccharide deacetylase
D9782_RS06105	COG2323	membrane
D9782_RS06120	COG2856	Zn peptidase
D9782_RS06130	COG3677	Transposase
D9782_RS06225	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9782_RS06265	COG1176	ABC-type spermidine putrescine transport system, permease component I
D9782_RS06270	COG3842	ATPase activity
D9782_RS06290	COG1595	DNA-templated transcription, initiation
D9782_RS06295	COG5662	AntiSigma factor
D9782_RS06300	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9782_RS06310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9782_RS06315	COG1309	transcriptional regulator
D9782_RS06330	COG3850	Histidine kinase
D9782_RS06330	COG5002	protein histidine kinase activity
D9782_RS06335	COG0577	efflux transmembrane transporter activity
D9782_RS06340	COG1136	(ABC) transporter
D9782_RS06380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9782_RS06385	COG1595	DNA-templated transcription, initiation
D9782_RS06395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9782_RS06460	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
D9782_RS06505	COG1725	Transcriptional regulator
D9782_RS06525	COG2814	Major facilitator Superfamily
D9782_RS06545	COG0768	penicillin binding
D9782_RS06555	COG0583	DNA-binding transcription factor activity
D9782_RS06560	COG2814	Major facilitator Superfamily
D9782_RS06565	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9782_RS06570	COG2814	Major facilitator Superfamily
D9782_RS06575	COG0366	Alpha amylase catalytic
D9782_RS06585	COG1846	Transcriptional regulator
D9782_RS06585	COG0456	acetyltransferase
D9782_RS06590	COG2271	Major facilitator Superfamily
D9782_RS06630	COG0402	S-adenosylhomocysteine deaminase activity
D9782_RS06635	COG0402	S-adenosylhomocysteine deaminase activity
D9782_RS06645	COG0583	DNA-binding transcription factor activity
D9782_RS06665	COG1801	Protein of unknown function DUF72
D9782_RS06670	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS06670	COG3773	Cell wall hydrolase
D9782_RS06680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9782_RS06690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9782_RS06695	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9782_RS06700	COG3766	membrane
D9782_RS06710	COG1842	Phage shock protein A
D9782_RS06740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9782_RS06745	COG1122	ATPase activity
D9782_RS06750	COG4721	ABC-type cobalt transport system, permease component
D9782_RS06760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9782_RS06765	COG3290	protein histidine kinase activity
D9782_RS06775	COG2358	TRAP transporter, solute receptor (TAXI family
D9782_RS06795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9782_RS06805	COG0531	amino acid
D9782_RS06830	COG1802	Transcriptional regulator
D9782_RS06845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9782_RS06880	COG0488	(ABC) transporter
D9782_RS06910	COG0714	Associated with various cellular activities
D9782_RS06920	COG0346	lactoylglutathione lyase activity
D9782_RS06935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9782_RS06975	COG0569	domain protein
D9782_RS06980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9782_RS06995	COG1388	LysM domain
D9782_RS07000	COG5002	protein histidine kinase activity
D9782_RS07000	COG3850	Histidine kinase
D9782_RS07015	COG1051	belongs to the nudix hydrolase family
D9782_RS07030	COG2217	Heavy metal translocating P-type atpase
D9782_RS07035	COG0740	serine-type endopeptidase activity
D9782_RS07045	COG3973	AAA domain
D9782_RS07060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS07065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS07070	COG1120	ATPase activity
D9782_RS07075	COG2819	hydrolase of the alpha beta superfamily
D9782_RS07085	COG0351	phosphomethylpyrimidine kinase
D9782_RS07090	COG0463	Glycosyl transferase, family 2
D9782_RS07090	COG0457	Tetratricopeptide repeat
D9782_RS07095	COG1271	oxidase subunit
D9782_RS07100	COG1294	oxidase, subunit
D9782_RS07105	COG4988	ABC transporter
D9782_RS07110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9782_RS07120	COG0560	Phosphoserine phosphatase
D9782_RS07125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9782_RS07125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9782_RS07145	COG1309	transcriptional regulator
D9782_RS07150	COG1131	(ABC) transporter
D9782_RS07155	COG3559	Exporter of polyketide antibiotics
D9782_RS07160	COG1132	(ABC) transporter
D9782_RS07165	COG1114	Component of the transport system for branched-chain amino acids
D9782_RS07170	COG1802	Transcriptional regulator
D9782_RS07180	COG0753	catalase activity
D9782_RS07185	COG0535	radical SAM domain protein
D9782_RS07200	COG2514	catechol 2,3-dioxygenase activity
D9782_RS07210	COG0400	carboxylic ester hydrolase activity
D9782_RS07215	COG1846	Transcriptional regulator
D9782_RS07220	COG0488	(ABC) transporter
D9782_RS07225	COG1695	Transcriptional regulator
D9782_RS07240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9782_RS07260	COG3173	Aminoglycoside phosphotransferase
D9782_RS07265	COG1413	lyase activity
D9782_RS07270	COG1607	acyl-coa hydrolase
D9782_RS07280	COG1846	Transcriptional regulator
D9782_RS07300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9782_RS07305	COG0640	Transcriptional regulator
D9782_RS07315	COG1131	(ABC) transporter
D9782_RS07365	COG0183	Belongs to the thiolase family
D9782_RS07370	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9782_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS07380	COG1024	Enoyl-CoA hydratase
D9782_RS07385	COG1024	Enoyl-CoA hydratase
D9782_RS07410	COG3396	Phenylacetate-CoA oxygenase
D9782_RS07435	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS07440	COG1024	Enoyl-CoA hydratase
D9782_RS07445	COG0346	lactoylglutathione lyase activity
D9782_RS07455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9782_RS07470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9782_RS07480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9782_RS07485	COG0460	homoserine dehydrogenase
D9782_RS07495	COG2814	Major facilitator Superfamily
D9782_RS07505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9782_RS07510	COG0583	DNA-binding transcription factor activity
D9782_RS07515	COG0372	Belongs to the citrate synthase family
D9782_RS07520	COG1620	l-lactate permease
D9782_RS07525	COG2186	Transcriptional regulator
D9782_RS07530	COG0247	lactate metabolic process
D9782_RS07535	COG1139	Iron-sulfur cluster binding protein
D9782_RS07540	COG1556	Lactate utilization protein
D9782_RS07550	COG0477	Major facilitator Superfamily
D9782_RS07570	COG0789	Transcriptional regulator
D9782_RS07575	COG0352	thiamine-phosphate diphosphorylase activity
D9782_RS07580	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9782_RS07590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9782_RS07610	COG0673	inositol 2-dehydrogenase activity
D9782_RS07640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9782_RS07665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D9782_RS07675	COG1215	transferase activity, transferring glycosyl groups
D9782_RS07680	COG3279	Response regulator of the LytR AlgR family
D9782_RS07710	COG4085	toxin activity
D9782_RS07710	COG0737	Belongs to the 5'-nucleotidase family
D9782_RS07710	COG1525	nuclease
D9782_RS07715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9782_RS07720	COG0157	Belongs to the NadC ModD family
D9782_RS07725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9782_RS07730	COG1104	cysteine desulfurase activity
D9782_RS07735	COG1827	regulation of RNA biosynthetic process
D9782_RS07740	COG3104	oligopeptide transport
D9782_RS07755	COG4145	pantothenate transmembrane transporter activity
D9782_RS07765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9782_RS07770	COG0693	protein deglycase activity
D9782_RS07780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9782_RS07795	COG5506	Protein of unknown function (DUF1694)
D9782_RS07810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9782_RS07830	COG1073	alpha beta
D9782_RS07835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS07850	COG0708	Exodeoxyribonuclease III
D9782_RS07855	COG1725	Transcriptional regulator
D9782_RS07860	COG1131	(ABC) transporter
D9782_RS07880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS07885	COG1510	regulation of RNA biosynthetic process
D9782_RS07895	COG1174	glycine betaine transport
D9782_RS07900	COG1732	Glycine betaine
D9782_RS07905	COG1174	glycine betaine transport
D9782_RS07940	COG2323	membrane
D9782_RS07950	COG0159	tryptophan synthase activity
D9782_RS07955	COG0133	tryptophan synthase activity
D9782_RS07965	COG0134	indole-3-glycerol-phosphate synthase activity
D9782_RS07970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9782_RS07975	COG0512	Glutamine amidotransferase of anthranilate synthase
D9782_RS07980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9782_RS08020	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9782_RS08025	COG0778	Nitroreductase
D9782_RS08050	COG1418	mRNA catabolic process
D9782_RS08055	COG1876	peptidase activity
D9782_RS08065	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9782_RS08075	COG0519	Catalyzes the synthesis of GMP from XMP
D9782_RS08090	COG0840	transmembrane signaling receptor activity
D9782_RS08105	COG0488	(ABC) transporter
D9782_RS08110	COG0656	L-ascorbic acid biosynthetic process
D9782_RS08125	COG3226	Transcriptional regulator
D9782_RS08140	COG2271	Major facilitator Superfamily
D9782_RS08145	COG1304	FMN binding
D9782_RS08160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS08165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9782_RS08170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS08175	COG4605	iron ion homeostasis
D9782_RS08180	COG4604	ABC transporter, ATP-binding protein
D9782_RS08185	COG4607	ABC-type enterochelin transport system periplasmic component
D9782_RS08190	COG2801	Transposase and inactivated derivatives
D9782_RS08205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9782_RS08210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9782_RS08215	COG0140	phosphoribosyl-ATP diphosphatase activity
D9782_RS08215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9782_RS08220	COG0107	imidazoleglycerol-phosphate synthase activity
D9782_RS08225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9782_RS08230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9782_RS08235	COG0131	Imidazoleglycerol-phosphate dehydratase
D9782_RS08240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9782_RS08245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9782_RS08250	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9782_RS08255	COG1196	nuclear chromosome segregation
D9782_RS08265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9782_RS08270	COG1126	abc transporter atp-binding protein
D9782_RS08275	COG0765	amino acid transport
D9782_RS08280	COG0765	amino acid transport
D9782_RS08290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9782_RS08300	COG0673	inositol 2-dehydrogenase activity
D9782_RS08305	COG1876	peptidase activity
D9782_RS08310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9782_RS08315	COG2839	Protein conserved in bacteria
D9782_RS08320	COG1335	isochorismatase
D9782_RS08325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS08330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9782_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9782_RS08350	COG0765	amino acid transport
D9782_RS08355	COG1126	abc transporter atp-binding protein
D9782_RS08360	COG0386	Belongs to the glutathione peroxidase family
D9782_RS08365	COG1054	Belongs to the UPF0176 family
D9782_RS08390	COG0601	transmembrane transport
D9782_RS08395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS08400	COG0444	Belongs to the ABC transporter superfamily
D9782_RS08405	COG4608	Belongs to the ABC transporter superfamily
D9782_RS08410	COG4166	transmembrane transport
D9782_RS08420	COG1268	BioY protein
D9782_RS08425	COG1937	Protein conserved in bacteria
D9782_RS08430	COG2217	Heavy metal translocating P-type atpase
D9782_RS08435	COG2608	mercury ion transmembrane transporter activity
D9782_RS08445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9782_RS08455	COG2084	Dehydrogenase
D9782_RS08490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9782_RS08495	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9782_RS08505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9782_RS08510	COG0745	RESPONSE REGULATOR receiver
D9782_RS08515	COG3850	Histidine kinase
D9782_RS08515	COG5002	protein histidine kinase activity
D9782_RS08520	COG1217	gtp-binding protein TYPA
D9782_RS08530	COG2133	pyrroloquinoline quinone binding
D9782_RS08545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9782_RS08550	COG1131	(ABC) transporter
D9782_RS08560	COG0183	Belongs to the thiolase family
D9782_RS08570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS08580	COG1404	Belongs to the peptidase S8 family
D9782_RS08595	COG0745	RESPONSE REGULATOR receiver
D9782_RS08600	COG3850	Histidine kinase
D9782_RS08600	COG5002	protein histidine kinase activity
D9782_RS08620	COG0737	Belongs to the 5'-nucleotidase family
D9782_RS08625	COG3639	organic phosphonate transmembrane transporter activity
D9782_RS08630	COG3639	organic phosphonate transmembrane transporter activity
D9782_RS08635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D9782_RS08640	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
D9782_RS08645	COG1597	lipid kinase activity
D9782_RS08650	COG1846	Transcriptional regulator
D9782_RS08675	COG0697	spore germination
D9782_RS08680	COG0513	Belongs to the DEAD box helicase family
D9782_RS08690	COG0546	phosphoglycolate phosphatase activity
D9782_RS08695	COG1609	Transcriptional regulator
D9782_RS08700	COG0705	Rhomboid family
D9782_RS08705	COG0736	holo-[acyl-carrier-protein] synthase activity
D9782_RS08710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9782_RS08710	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D9782_RS08715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9782_RS08720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9782_RS08730	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9782_RS08735	COG1366	Belongs to the anti-sigma-factor antagonist family
D9782_RS08740	COG1366	Belongs to the anti-sigma-factor antagonist family
D9782_RS08745	COG2172	sigma factor antagonist activity
D9782_RS08750	COG2208	phosphoserine phosphatase activity
D9782_RS08755	COG1366	Belongs to the anti-sigma-factor antagonist family
D9782_RS08760	COG2172	sigma factor antagonist activity
D9782_RS08765	COG1191	sigma factor activity
D9782_RS08770	COG2208	phosphoserine phosphatase activity
D9782_RS08780	COG2183	response to ionizing radiation
D9782_RS08785	COG0753	catalase activity
D9782_RS08790	COG3091	SprT-like family
D9782_RS08880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9782_RS08885	COG0802	atpase or kinase
D9782_RS08890	COG1214	PFAM Peptidase M22, glycoprotease
D9782_RS08895	COG0456	acetyltransferase
D9782_RS08900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9782_RS08905	COG0772	Belongs to the SEDS family
D9782_RS08910	COG0488	(ABC) transporter
D9782_RS08915	COG0315	cyclic pyranopterin monophosphate synthase activity
D9782_RS08920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9782_RS08940	COG1266	CAAX protease self-immunity
D9782_RS08945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9782_RS08950	COG0459	protein refolding
D9782_RS08960	COG0514	ATP-dependent DNA helicase (RecQ)
D9782_RS08965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS08970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS08975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9782_RS08990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9782_RS09010	COG2816	NAD+ diphosphatase activity
D9782_RS09025	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9782_RS09025	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS09030	COG3739	integral membrane protein
D9782_RS09040	COG1714	RDD family
D9782_RS09055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS09060	COG1733	regulation of RNA biosynthetic process
D9782_RS09075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS09170	COG1716	ATPase activity
D9782_RS09180	COG0515	serine threonine protein kinase
D9782_RS09190	COG0840	transmembrane signaling receptor activity
D9782_RS09205	COG1136	(ABC) transporter
D9782_RS09215	COG0789	Transcriptional regulator
D9782_RS09245	COG0681	Belongs to the peptidase S26 family
D9782_RS09255	COG3227	Zinc metalloprotease (Elastase)
D9782_RS09270	COG1733	regulation of RNA biosynthetic process
D9782_RS09290	COG0693	protein deglycase activity
D9782_RS09295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9782_RS09320	COG1454	alcohol dehydrogenase
D9782_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS09330	COG1510	regulation of RNA biosynthetic process
D9782_RS09355	COG2200	EAL domain
D9782_RS09375	COG1694	Mazg nucleotide pyrophosphohydrolase
D9782_RS09380	COG0753	catalase activity
D9782_RS09390	COG1309	transcriptional regulator
D9782_RS09395	COG0840	transmembrane signaling receptor activity
D9782_RS09410	COG0697	spore germination
D9782_RS09415	COG0531	amino acid
D9782_RS09435	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D9782_RS09445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9782_RS09450	COG0006	proline dipeptidase activity
D9782_RS09460	COG1802	Transcriptional regulator
D9782_RS09465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9782_RS09475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9782_RS09480	COG0714	Associated with various cellular activities
D9782_RS09485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9782_RS09490	COG1305	Transglutaminase-like
D9782_RS09495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9782_RS09495	COG0519	Catalyzes the synthesis of GMP from XMP
D9782_RS09510	COG0640	Transcriptional regulator
D9782_RS09530	COG1454	alcohol dehydrogenase
D9782_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS09540	COG1882	Formate acetyltransferase
D9782_RS09545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D9782_RS09550	COG2252	PERMEase
D9782_RS09560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9782_RS09565	COG2258	MOSC domain
D9782_RS09575	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9782_RS09580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9782_RS09585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9782_RS09590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9782_RS09595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9782_RS09600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9782_RS09605	COG0047	phosphoribosylformylglycinamidine synthase activity
D9782_RS09610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9782_RS09615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9782_RS09620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9782_RS09625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9782_RS09630	COG0138	bifunctional purine biosynthesis protein purh
D9782_RS09635	COG0151	Belongs to the GarS family
D9782_RS09655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9782_RS09660	COG1470	cell adhesion involved in biofilm formation
D9782_RS09665	COG4496	protein, YerC YecD
D9782_RS09670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9782_RS09675	COG0210	DNA helicase
D9782_RS09680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9782_RS09685	COG4851	CamS sex pheromone cAM373 precursor
D9782_RS09695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9782_RS09705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9782_RS09710	COG0154	amidase activity
D9782_RS09715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9782_RS09720	COG1597	lipid kinase activity
D9782_RS09725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9782_RS09760	COG1695	Transcriptional regulator
D9782_RS09780	COG0840	transmembrane signaling receptor activity
D9782_RS09785	COG1695	Transcriptional regulator
D9782_RS09800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS09800	COG2207	Transcriptional regulator
D9782_RS09805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS09810	COG0662	Cupin 2, conserved barrel domain protein
D9782_RS09815	COG1695	Transcriptional regulator
D9782_RS09830	COG4978	Transcriptional regulator
D9782_RS09830	COG0789	Transcriptional regulator
D9782_RS09840	COG0697	spore germination
D9782_RS09845	COG1917	Cupin 2, conserved barrel domain protein
D9782_RS09845	COG2207	Transcriptional regulator
D9782_RS09855	COG0494	nUDIX hydrolase
D9782_RS09865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9782_RS09950	COG2409	Drug exporters of the RND superfamily
D9782_RS09980	COG3655	Transcriptional regulator
D9782_RS10000	COG0583	DNA-binding transcription factor activity
D9782_RS10005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D9782_RS10010	COG2261	transglycosylase associated protein
D9782_RS10015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9782_RS10050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9782_RS10060	COG1522	sequence-specific DNA binding
D9782_RS10065	COG0693	protein deglycase activity
D9782_RS10070	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS10075	COG2264	protein methyltransferase activity
D9782_RS10080	COG1595	DNA-templated transcription, initiation
D9782_RS10090	COG0583	DNA-binding transcription factor activity
D9782_RS10095	COG0372	Belongs to the citrate synthase family
D9782_RS10100	COG2079	MmgE PrpD family protein
D9782_RS10105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9782_RS10110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9782_RS10115	COG0765	amino acid transport
D9782_RS10140	COG2910	NAD(P)H-binding
D9782_RS10145	COG1959	2 iron, 2 sulfur cluster binding
D9782_RS10150	COG0018	arginyl-trna synthetase
D9782_RS10165	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9782_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS10185	COG2197	response regulator
D9782_RS10200	COG0166	Belongs to the GPI family
D9782_RS10205	COG3103	Sh3 type 3 domain protein
D9782_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS10205	COG4991	sh3 domain protein
D9782_RS10215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS10220	COG3835	regulator
D9782_RS10225	COG0277	FAD linked oxidase domain protein
D9782_RS10230	COG0247	lactate metabolic process
D9782_RS10235	COG4412	M6 family metalloprotease domain protein
D9782_RS10235	COG1404	Belongs to the peptidase S8 family
D9782_RS10240	COG0840	transmembrane signaling receptor activity
D9782_RS10245	COG0307	riboflavin synthase, alpha
D9782_RS10250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9782_RS10250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9782_RS10255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9782_RS10265	COG0488	(ABC) transporter
D9782_RS10315	COG0733	neurotransmitter:sodium symporter activity
D9782_RS10325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D9782_RS10335	COG1757	Na H antiporter
D9782_RS10340	COG0436	Aminotransferase
D9782_RS10345	COG0028	Belongs to the TPP enzyme family
D9782_RS10350	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS10360	COG1414	Transcriptional regulator
D9782_RS10370	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS10375	COG1960	acyl-CoA dehydrogenase activity
D9782_RS10380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D9782_RS10385	COG1077	Cell shape determining protein MreB Mrl
D9782_RS10390	COG2340	Cysteine-rich secretory protein family
D9782_RS10405	COG2066	Belongs to the glutaminase family
D9782_RS10410	COG2135	peptidase activity
D9782_RS10415	COG1115	amino acid carrier protein
D9782_RS10420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9782_RS10430	COG1295	ribonuclease BN
D9782_RS10435	COG2217	Heavy metal translocating P-type atpase
D9782_RS10440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9782_RS10445	COG0765	amino acid transport
D9782_RS10450	COG0477	Major facilitator Superfamily
D9782_RS10465	COG2056	Na+-H+ antiporter family
D9782_RS10480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9782_RS10485	COG0542	response to heat
D9782_RS10490	COG2333	competence protein COMEC
D9782_RS10490	COG0658	competence protein
D9782_RS10515	COG1131	(ABC) transporter
D9782_RS10525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9782_RS10530	COG1131	(ABC) transporter
D9782_RS10545	COG1725	Transcriptional regulator
D9782_RS10555	COG1396	sequence-specific DNA binding
D9782_RS10575	COG1090	epimerase
D9782_RS10580	COG2137	regulation of response to DNA damage stimulus
D9782_RS10590	COG1988	membrane-bound metal-dependent
D9782_RS10595	COG1194	a g-specific adenine glycosylase
D9782_RS10605	COG3557	Belongs to the UPF0374 family
D9782_RS10610	COG1132	(ABC) transporter
D9782_RS10620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9782_RS10625	COG0577	efflux transmembrane transporter activity
D9782_RS10630	COG1136	(ABC) transporter
D9782_RS10635	COG2205	protein histidine kinase activity
D9782_RS10640	COG0745	RESPONSE REGULATOR receiver
D9782_RS10650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9782_RS10665	COG2096	Adenosyltransferase
D9782_RS10670	COG0735	belongs to the Fur family
D9782_RS10770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9782_RS10775	COG2169	Transcriptional regulator
D9782_RS10790	COG0788	formyltetrahydrofolate deformylase activity
D9782_RS10795	COG4977	sequence-specific DNA binding
D9782_RS10800	COG3486	L-lysine 6-monooxygenase (NADPH) activity
D9782_RS10805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9782_RS10810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9782_RS10815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9782_RS10830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9782_RS10830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9782_RS10835	COG0527	aspartate kinase activity
D9782_RS10840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9782_RS10845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9782_RS10850	COG0531	amino acid
D9782_RS10855	COG0596	Alpha beta hydrolase
D9782_RS10885	COG0745	RESPONSE REGULATOR receiver
D9782_RS10890	COG2205	protein histidine kinase activity
D9782_RS10905	COG1136	(ABC) transporter
D9782_RS10910	COG0577	efflux transmembrane transporter activity
D9782_RS10915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9782_RS10920	COG4555	ABC transporter
D9782_RS10985	COG0583	DNA-binding transcription factor activity
D9782_RS11000	COG2226	methyltransferase
D9782_RS11005	COG2207	Transcriptional regulator
D9782_RS11005	COG3708	Transcriptional regulator
D9782_RS11020	COG0768	penicillin binding
D9782_RS11035	COG3192	ethanolamine utilization protein
D9782_RS11040	COG2364	Membrane
D9782_RS11050	COG0659	secondary active sulfate transmembrane transporter activity
D9782_RS11055	COG0589	response to stress
D9782_RS11060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9782_RS11080	COG1227	inorganic diphosphatase activity
D9782_RS11095	COG1970	mechanosensitive ion channel activity
D9782_RS11115	COG4474	Belongs to the UPF0398 family
D9782_RS11125	COG2968	Membrane
D9782_RS11145	COG1247	-acetyltransferase
D9782_RS11150	COG0346	lactoylglutathione lyase activity
D9782_RS11155	COG0456	acetyltransferase
D9782_RS11160	COG1794	racemase activity, acting on amino acids and derivatives
D9782_RS11180	COG0494	nUDIX hydrolase
D9782_RS11195	COG2814	Major facilitator Superfamily
D9782_RS11235	COG2814	Major facilitator Superfamily
D9782_RS11240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9782_RS11260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9782_RS11270	COG0277	FAD linked oxidase domain protein
D9782_RS11285	COG1957	nucleoside hydrolase
D9782_RS11290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9782_RS11305	COG0326	Molecular chaperone. Has ATPase activity
D9782_RS11320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9782_RS11325	COG1116	anion transmembrane transporter activity
D9782_RS11335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9782_RS11340	COG1011	Hydrolase
D9782_RS11345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9782_RS11355	COG1966	Carbon starvation protein
D9782_RS11360	COG1609	Transcriptional regulator
D9782_RS11365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9782_RS11370	COG1129	ABC transporter
D9782_RS11375	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9782_RS11380	COG1879	ABC-type sugar transport system periplasmic component
D9782_RS11395	COG0318	PFAM AMP-dependent synthetase and ligase
D9782_RS11415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9782_RS11425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9782_RS11430	COG2233	PERMEase
D9782_RS11435	COG2814	Major facilitator Superfamily
D9782_RS11475	COG3336	cytochrome c oxidase
D9782_RS11480	COG4585	Histidine kinase
D9782_RS11485	COG2197	response regulator
D9782_RS11490	COG1131	(ABC) transporter
D9782_RS11510	COG2318	DinB family
D9782_RS11525	COG3708	Transcriptional regulator
D9782_RS11525	COG2207	Transcriptional regulator
D9782_RS11535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9782_RS11540	COG4946	Tricorn protease homolog
D9782_RS11540	COG1506	peptidase
D9782_RS11540	COG0823	Involved in the tonB-independent uptake of proteins
D9782_RS11580	COG0567	Dehydrogenase, E1 component
D9782_RS11585	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9782_RS11595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9782_RS11600	COG0534	Mate efflux family protein
D9782_RS11605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9782_RS11625	COG1132	(ABC) transporter
D9782_RS11630	COG1132	(ABC) transporter
D9782_RS11635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9782_RS11645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9782_RS11650	COG1510	regulation of RNA biosynthetic process
D9782_RS11655	COG3246	L-lysine catabolic process to acetate
D9782_RS11670	COG1191	sigma factor activity
D9782_RS11690	COG2226	methyltransferase
D9782_RS11695	COG1854	S-ribosylhomocysteine lyase activity
D9782_RS11700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9782_RS11705	COG0626	cystathionine gamma-synthase activity
D9782_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS11730	COG1131	(ABC) transporter
D9782_RS11735	COG0024	Methionine aminopeptidase
D9782_RS11740	COG1757	Na H antiporter
D9782_RS11745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9782_RS11755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9782_RS11775	COG2270	Major facilitator Superfamily
D9782_RS11805	COG0114	fumarate hydratase activity
D9782_RS11815	COG3842	ATPase activity
D9782_RS11820	COG2508	Transcriptional regulator
D9782_RS11825	COG3679	Belongs to the UPF0342 family
D9782_RS11830	COG1024	Enoyl-CoA hydratase
D9782_RS11840	COG4152	abc transporter atp-binding protein
D9782_RS11845	COG1668	transmembrane transport
D9782_RS11850	COG0420	3'-5' exonuclease activity
D9782_RS11860	COG1510	regulation of RNA biosynthetic process
D9782_RS11865	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9782_RS11875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9782_RS11905	COG4175	Glycine betaine
D9782_RS11905	COG0517	IMP dehydrogenase activity
D9782_RS11935	COG0537	adenosine 5'-monophosphoramidase activity
D9782_RS11940	COG1131	(ABC) transporter
D9782_RS11945	COG4473	ABC transporter
D9782_RS11955	COG1473	amidohydrolase
D9782_RS11960	COG2193	ferroxidase activity
D9782_RS11970	COG2814	Major facilitator Superfamily
D9782_RS11980	COG4585	Histidine kinase
D9782_RS11985	COG2197	response regulator
D9782_RS11990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9782_RS11995	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS11995	COG3118	belongs to the thioredoxin family
D9782_RS12010	COG2329	Antibiotic biosynthesis monooxygenase
D9782_RS12020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9782_RS12025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9782_RS12030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9782_RS12035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9782_RS12045	COG1234	tRNA 3'-trailer cleavage
D9782_RS12050	COG0095	Lipoate-protein ligase
D9782_RS12060	COG0318	PFAM AMP-dependent synthetase and ligase
D9782_RS12075	COG0398	Pfam SNARE associated Golgi protein
D9782_RS12085	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9782_RS12090	COG1074	ATP-dependent DNA helicase activity
D9782_RS12125	COG2311	Membrane
D9782_RS12135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9782_RS12145	COG0366	Alpha amylase catalytic
D9782_RS12155	COG0584	glycerophosphoryl diester phosphodiesterase
D9782_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS12175	COG1307	EDD domain protein, DegV family
D9782_RS12180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9782_RS12205	COG0561	phosphatase activity
D9782_RS12210	COG1073	alpha beta
D9782_RS12215	COG2151	metal-sulfur cluster biosynthetic enzyme
D9782_RS12230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9782_RS12240	COG1968	undecaprenyl-diphosphatase activity
D9782_RS12260	COG1744	ABC transporter substrate-binding protein PnrA-like
D9782_RS12265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9782_RS12270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9782_RS12285	COG0180	Tryptophanyl-tRNA synthetase
D9782_RS12290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9782_RS12295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9782_RS12300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9782_RS12315	COG2801	Transposase and inactivated derivatives
D9782_RS12325	COG0456	acetyltransferase
D9782_RS12330	COG0004	ammonium transporteR
D9782_RS12335	COG0347	Belongs to the P(II) protein family
D9782_RS12340	COG1393	Belongs to the ArsC family
D9782_RS12345	COG4862	establishment of competence for transformation
D9782_RS12365	COG1164	Oligoendopeptidase f
D9782_RS12380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9782_RS12385	COG2346	COG2346, Truncated hemoglobins
D9782_RS12390	COG4116	CYTH
D9782_RS12395	COG2357	RelA SpoT domain protein
D9782_RS12405	COG0564	pseudouridine synthase activity
D9782_RS12410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9782_RS12415	COG2239	Acts as a magnesium transporter
D9782_RS12445	COG2323	membrane
D9782_RS12450	COG2153	protein acetylation
D9782_RS12455	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9782_RS12460	COG2382	esterase
D9782_RS12465	COG1132	(ABC) transporter
D9782_RS12470	COG1132	(ABC) transporter
D9782_RS12480	COG0582	viral genome integration into host DNA
D9782_RS12510	COG0419	ATPase involved in DNA repair
D9782_RS12530	COG1396	sequence-specific DNA binding
D9782_RS12550	COG1396	sequence-specific DNA binding
D9782_RS12570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9782_RS12630	COG0561	phosphatase activity
D9782_RS12635	COG1349	DNA-binding transcription factor activity
D9782_RS12645	COG1272	protein, Hemolysin III
D9782_RS12650	COG1295	ribonuclease BN
D9782_RS12665	COG2814	Major facilitator Superfamily
D9782_RS12685	COG1757	Na H antiporter
D9782_RS12695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9782_RS12700	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9782_RS12700	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9782_RS12705	COG1733	regulation of RNA biosynthetic process
D9782_RS12720	COG0431	NADPH-dependent FMN reductase
D9782_RS12735	COG3775	system Galactitol-specific IIC component
D9782_RS12740	COG1070	Carbohydrate kinase
D9782_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS12750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9782_RS12760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9782_RS12765	COG0431	NADPH-dependent FMN reductase
D9782_RS12770	COG3420	alginic acid biosynthetic process
D9782_RS12785	COG0204	Acyl-transferase
D9782_RS12800	COG0583	DNA-binding transcription factor activity
D9782_RS12820	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS12830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9782_RS12855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9782_RS12870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9782_RS12875	COG0720	synthase
D9782_RS12880	COG0602	queuosine metabolic process
D9782_RS12890	COG0772	Belongs to the SEDS family
D9782_RS12895	COG0772	Belongs to the SEDS family
D9782_RS12900	COG3425	synthase
D9782_RS12910	COG4166	transmembrane transport
D9782_RS12915	COG0346	lactoylglutathione lyase activity
D9782_RS12925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9782_RS12940	COG3339	Conserved Protein
D9782_RS12945	COG3711	transcriptional antiterminator
D9782_RS12945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS12955	COG3037	sugar-specific permease SgaT UlaA
D9782_RS12960	COG0861	Integral membrane protein TerC family
D9782_RS12975	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9782_RS12985	COG0385	Bile acid
D9782_RS13000	COG1228	amidohydrolase
D9782_RS13015	COG1917	Cupin 2, conserved barrel domain protein
D9782_RS13020	COG0456	acetyltransferase
D9782_RS13025	COG0454	-acetyltransferase
D9782_RS13025	COG0456	acetyltransferase
D9782_RS13035	COG2076	Multidrug Resistance protein
D9782_RS13040	COG2076	Multidrug Resistance protein
D9782_RS13050	COG1408	metallophosphoesterase
D9782_RS13060	COG5505	Protein of unknown function (DUF819)
D9782_RS13065	COG5564	TIM-barrel signal transduction protein
D9782_RS13075	COG5564	TIM-barrel signal transduction protein
D9782_RS13095	COG1533	DNA photolyase activity
D9782_RS13120	COG1937	Protein conserved in bacteria
D9782_RS13125	COG2210	Belongs to the sulfur carrier protein TusA family
D9782_RS13130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS13135	COG0425	Belongs to the sulfur carrier protein TusA family
D9782_RS13135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS13140	COG2210	Belongs to the sulfur carrier protein TusA family
D9782_RS13145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS13145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS13150	COG0425	Belongs to the sulfur carrier protein TusA family
D9782_RS13155	COG0730	response to heat
D9782_RS13160	COG0753	catalase activity
D9782_RS13180	COG0626	cystathionine gamma-synthase activity
D9782_RS13185	COG1940	carbohydrate kinase activity
D9782_RS13195	COG0747	negative chemotaxis
D9782_RS13200	COG0601	transmembrane transport
D9782_RS13210	COG0444	Belongs to the ABC transporter superfamily
D9782_RS13215	COG4608	Belongs to the ABC transporter superfamily
D9782_RS13225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9782_RS13230	COG3142	Participates in the control of copper homeostasis
D9782_RS13250	COG2391	methyltransferase activity
D9782_RS13255	COG1785	Belongs to the alkaline phosphatase family
D9782_RS13275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9782_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS13305	COG3336	cytochrome c oxidase
D9782_RS13310	COG1349	DNA-binding transcription factor activity
D9782_RS13335	COG2268	Band 7 protein
D9782_RS13340	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9782_RS13345	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS13365	COG1615	UPF0182 protein
D9782_RS13385	COG4842	Belongs to the WXG100 family
D9782_RS13390	COG5417	Belongs to the EsaB family
D9782_RS13395	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9782_RS13400	COG1674	ftsk spoiiie
D9782_RS13400	COG0433	COG0433 Predicted ATPase
D9782_RS13405	COG1511	domain protein
D9782_RS13415	COG5504	Zn-dependent protease
D9782_RS13420	COG2226	methyltransferase
D9782_RS13435	COG1309	transcriptional regulator
D9782_RS13450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9782_RS13460	COG2188	Transcriptional regulator
D9782_RS13480	COG1735	metal-dependent hydrolase with the TIM-barrel fold
D9782_RS13485	COG0626	cystathionine gamma-synthase activity
D9782_RS13490	COG3457	Alanine racemase
D9782_RS13495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9782_RS13500	COG0667	Aldo Keto reductase
D9782_RS13505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9782_RS13525	COG2027	D-alanyl-D-alanine carboxypeptidase
D9782_RS13550	COG1252	NADH dehydrogenase
D9782_RS13555	COG2720	vancomycin resistance protein
D9782_RS13570	COG2353	YceI-like domain
D9782_RS13585	COG3859	Proton-coupled thiamine transporter YuaJ
D9782_RS13595	COG3069	C4-dicarboxylate transmembrane transporter activity
D9782_RS13600	COG1966	Carbon starvation protein
D9782_RS13610	COG0003	Pfam Anion-transporting ATPase
D9782_RS13615	COG0604	alcohol dehydrogenase
D9782_RS13625	COG1301	dicarboxylic acid transport
D9782_RS13630	COG2323	membrane
D9782_RS13645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9782_RS13670	COG0778	Nitroreductase
D9782_RS13675	COG0303	'Molybdopterin
D9782_RS13685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9782_RS13700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9782_RS13720	COG0436	Aminotransferase
D9782_RS13730	COG0697	spore germination
D9782_RS13745	COG1999	signal sequence binding
D9782_RS13750	COG1408	metallophosphoesterase
D9782_RS13760	COG0640	Transcriptional regulator
D9782_RS13765	COG0517	IMP dehydrogenase activity
D9782_RS13770	COG2171	N-acyltransferase activity
D9782_RS13775	COG1473	amidohydrolase
D9782_RS13785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS13790	COG1132	(ABC) transporter
D9782_RS13795	COG1132	(ABC) transporter
D9782_RS13805	COG2801	Transposase and inactivated derivatives
D9782_RS13810	COG0569	domain protein
D9782_RS13815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9782_RS13820	COG5503	Protein of unknown function (DUF1447)
D9782_RS13825	COG0561	phosphatase activity
D9782_RS13830	COG0242	peptide deformylase activity
D9782_RS13855	COG0022	dehydrogenase e1 component
D9782_RS13875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9782_RS13890	COG1982	Orn Lys Arg decarboxylase major
D9782_RS13895	COG4476	Belongs to the UPF0223 family
D9782_RS13910	COG4493	Belongs to the UPF0637 family
D9782_RS13920	COG0483	inositol monophosphate 1-phosphatase activity
D9782_RS13930	COG4896	Protein conserved in bacteria
D9782_RS13945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9782_RS13950	COG4838	Belongs to the UPF0358 family
D9782_RS13955	COG0772	Belongs to the SEDS family
D9782_RS13960	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9782_RS13970	COG0109	protoheme IX farnesyltransferase activity
D9782_RS13975	COG2010	Cytochrome c
D9782_RS13975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9782_RS13985	COG1845	cytochrome c oxidase, subunit III
D9782_RS13995	COG3336	cytochrome c oxidase
D9782_RS14000	COG2322	membrane
D9782_RS14020	COG2340	Cysteine-rich secretory protein family
D9782_RS14035	COG3679	Belongs to the UPF0342 family
D9782_RS14040	COG4471	UPF0298 protein
D9782_RS14050	COG0742	ribosomal rna small subunit methyltransferase
D9782_RS14055	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9782_RS14060	COG3314	Sporulation integral membrane protein YlbJ
D9782_RS14065	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9782_RS14070	COG1323	Belongs to the UPF0348 family
D9782_RS14075	COG1399	metal-binding, possibly nucleic acid-binding protein
D9782_RS14080	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9782_RS14090	COG0454	-acetyltransferase
D9782_RS14100	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9782_RS14110	COG2001	Belongs to the MraZ family
D9782_RS14115	COG0275	rRNA processing
D9782_RS14120	COG4839	cell division protein FtsL
D9782_RS14125	COG0768	penicillin binding
D9782_RS14130	COG0768	penicillin binding
D9782_RS14135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9782_RS14140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9782_RS14145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9782_RS14150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9782_RS14155	COG0772	Belongs to the SEDS family
D9782_RS14160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9782_RS14165	COG0849	cell division
D9782_RS14170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9782_RS14180	COG1191	sigma factor activity
D9782_RS14185	COG1191	sigma factor activity
D9782_RS14190	COG1873	PFAM PRC-barrel domain
D9782_RS14195	COG1496	oxidoreductase activity
D9782_RS14200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9782_RS14205	COG1799	cell septum assembly
D9782_RS14210	COG0762	integral membrane protein
D9782_RS14220	COG3599	regulation of cell shape
D9782_RS14225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9782_RS14245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9782_RS14255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9782_RS14260	COG0564	pseudouridine synthase activity
D9782_RS14265	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9782_RS14270	COG0540	Belongs to the ATCase OTCase family
D9782_RS14280	COG0505	Belongs to the CarA family
D9782_RS14295	COG0167	dihydroorotate dehydrogenase activity
D9782_RS14300	COG0284	orotidine-5'-phosphate decarboxylase activity
D9782_RS14305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9782_RS14310	COG3854	ATPases associated with a variety of cellular activities
D9782_RS14350	COG0511	ligase activity, forming carbon-carbon bonds
D9782_RS14355	COG0439	Biotin carboxylase
D9782_RS14360	COG1302	Protein conserved in bacteria
D9782_RS14365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9782_RS14370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9782_RS14375	COG1570	exodeoxyribonuclease VII activity
D9782_RS14380	COG1722	exodeoxyribonuclease VII activity
D9782_RS14395	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9782_RS14400	COG1438	arginine binding
D9782_RS14405	COG0497	DNA recombination
D9782_RS14410	COG0750	zinc metalloprotease
D9782_RS14415	COG0745	RESPONSE REGULATOR receiver
D9782_RS14420	COG0527	aspartate kinase activity
D9782_RS14430	COG3290	protein histidine kinase activity
D9782_RS14430	COG3829	transcription factor binding
D9782_RS14435	COG0280	phosphate acetyltransferase
D9782_RS14445	COG3426	butyrate kinase activity
D9782_RS14450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9782_RS14455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9782_RS14460	COG0022	dehydrogenase e1 component
D9782_RS14465	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9782_RS14475	COG4129	membrane
D9782_RS14485	COG0346	lactoylglutathione lyase activity
D9782_RS14490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9782_RS14495	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9782_RS14500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9782_RS14505	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS14510	COG1234	tRNA 3'-trailer cleavage
D9782_RS14515	COG1902	pentaerythritol trinitrate reductase activity
D9782_RS14520	COG0584	glycerophosphoryl diester phosphodiesterase
D9782_RS14525	COG4187	Peptidase family M20/M25/M40
D9782_RS14530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS14535	COG0300	oxidoreductase activity
D9782_RS14545	COG0667	Aldo Keto reductase
D9782_RS14550	COG0494	nUDIX hydrolase
D9782_RS14555	COG1379	DNA repair
D9782_RS14560	COG1300	Membrane
D9782_RS14565	COG0735	belongs to the Fur family
D9782_RS14575	COG4974	Belongs to the 'phage' integrase family
D9782_RS14585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9782_RS14600	COG1686	Belongs to the peptidase S11 family
D9782_RS14610	COG2172	sigma factor antagonist activity
D9782_RS14630	COG0697	spore germination
D9782_RS14640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9782_RS14660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9782_RS14665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9782_RS14675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9782_RS14680	COG1686	Belongs to the peptidase S11 family
D9782_RS14685	COG2715	membrane protein required for spore maturation
D9782_RS14690	COG0700	Nucleoside recognition
D9782_RS14695	COG1187	pseudouridine synthase activity
D9782_RS14700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS14705	COG1333	cytochrome c biogenesis protein
D9782_RS14710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9782_RS14715	COG0745	RESPONSE REGULATOR receiver
D9782_RS14720	COG5002	protein histidine kinase activity
D9782_RS14735	COG1595	DNA-templated transcription, initiation
D9782_RS14745	COG4955	Helix-turn-helix domain
D9782_RS14750	COG0514	ATP-dependent DNA helicase (RecQ)
D9782_RS14755	COG1266	CAAX protease self-immunity
D9782_RS14765	COG1408	metallophosphoesterase
D9782_RS14770	COG4862	establishment of competence for transformation
D9782_RS14775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9782_RS14780	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS14790	COG2339	peptidase activity
D9782_RS14800	COG3773	Cell wall hydrolase
D9782_RS14800	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS14805	COG2959	enzyme of heme biosynthesis
D9782_RS14815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9782_RS14825	COG0539	negative regulation of cytoplasmic translation
D9782_RS14840	COG1160	GTP binding
D9782_RS14845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9782_RS14865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9782_RS14870	COG0776	regulation of translation
D9782_RS14885	COG0142	geranyltranstransferase activity
D9782_RS14890	COG2226	methyltransferase
D9782_RS14895	COG0142	geranyltranstransferase activity
D9782_RS14900	COG0105	UTP biosynthetic process
D9782_RS14905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9782_RS14910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9782_RS14915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9782_RS14920	COG4401	Chorismate mutase type I
D9782_RS14925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9782_RS14930	COG0287	Prephenate dehydrogenase
D9782_RS14935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9782_RS14950	COG5582	Belongs to the UPF0302 family
D9782_RS14960	COG0723	plastoquinol--plastocyanin reductase activity
D9782_RS14965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9782_RS14975	COG4347	Protein of unknown function (DUF1405)
D9782_RS14985	COG2738	Putative neutral zinc metallopeptidase
D9782_RS14990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9782_RS14995	COG1694	Mazg nucleotide pyrophosphohydrolase
D9782_RS15000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9782_RS15005	COG1803	Methylglyoxal synthase
D9782_RS15010	COG0438	transferase activity, transferring glycosyl groups
D9782_RS15015	COG0617	tRNA 3'-terminal CCA addition
D9782_RS15025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9782_RS15025	COG1199	ATP-dependent helicase activity
D9782_RS15040	COG0436	Aminotransferase
D9782_RS15045	COG0017	Asparaginyl-tRNA synthetase
D9782_RS15050	COG3935	DnaD domain protein
D9782_RS15055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9782_RS15060	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9782_RS15060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9782_RS15065	COG3331	DNA recombination
D9782_RS15085	COG0295	cytidine deaminase activity
D9782_RS15095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9782_RS15110	COG3835	regulator
D9782_RS15115	COG3599	regulation of cell shape
D9782_RS15130	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9782_RS15135	COG3424	synthase
D9782_RS15140	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9782_RS15145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9782_RS15150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9782_RS15160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9782_RS15175	COG1418	mRNA catabolic process
D9782_RS15180	COG1388	LysM domain
D9782_RS15180	COG0791	NLP P60 protein
D9782_RS15185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9782_RS15190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9782_RS15205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9782_RS15210	COG0805	protein transport
D9782_RS15220	COG0156	8-amino-7-oxononanoate synthase activity
D9782_RS15235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9782_RS15235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9782_RS15270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9782_RS15270	COG0723	plastoquinol--plastocyanin reductase activity
D9782_RS15285	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9782_RS15290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS15290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS15290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS15295	COG1105	Belongs to the carbohydrate kinase PfkB family
D9782_RS15300	COG1349	DNA-binding transcription factor activity
D9782_RS15320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9782_RS15335	COG2197	response regulator
D9782_RS15340	COG4585	Histidine kinase
D9782_RS15350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9782_RS15360	COG4978	Transcriptional regulator
D9782_RS15360	COG0789	Transcriptional regulator
D9782_RS15370	COG1472	Belongs to the glycosyl hydrolase 3 family
D9782_RS15375	COG0582	viral genome integration into host DNA
D9782_RS15380	COG1357	PFAM Pentapeptide repeats (8 copies)
D9782_RS15405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9782_RS15415	COG0390	transport system, permease component
D9782_RS15420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9782_RS15425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9782_RS15430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9782_RS15435	COG0517	IMP dehydrogenase activity
D9782_RS15435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9782_RS15440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9782_RS15445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9782_RS15450	COG1024	Enoyl-CoA hydratase
D9782_RS15455	COG0511	ligase activity, forming carbon-carbon bonds
D9782_RS15460	COG0439	Biotin carboxylase
D9782_RS15465	COG0318	PFAM AMP-dependent synthetase and ligase
D9782_RS15470	COG1960	acyl-CoA dehydrogenase activity
D9782_RS15480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9782_RS15485	COG0187	DNA topoisomerase II activity
D9782_RS15490	COG1832	CoA-binding protein
D9782_RS15505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9782_RS15510	COG1469	GTP cyclohydrolase I activity
D9782_RS15515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9782_RS15520	COG4841	protein insertion into membrane
D9782_RS15530	COG0824	Thioesterase
D9782_RS15545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS15550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9782_RS15555	COG4191	Histidine kinase
D9782_RS15565	COG4846	Membrane protein involved in cytochrome C biogenesis
D9782_RS15570	COG2201	protein-glutamate methylesterase activity
D9782_RS15575	COG2111	Na H antiporter
D9782_RS15580	COG0785	Cytochrome C biogenesis protein
D9782_RS15585	COG3763	UPF0154 protein
D9782_RS15595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9782_RS15600	COG4224	UPF0291 protein
D9782_RS15605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9782_RS15610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9782_RS15645	COG2076	Multidrug Resistance protein
D9782_RS15650	COG2076	Multidrug Resistance protein
D9782_RS15685	COG3708	Transcriptional regulator
D9782_RS15685	COG2207	Transcriptional regulator
D9782_RS15695	COG0730	response to heat
D9782_RS15700	COG0583	DNA-binding transcription factor activity
D9782_RS15720	COG3773	Cell wall hydrolase
D9782_RS15750	COG0425	Belongs to the sulfur carrier protein TusA family
D9782_RS15750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS15755	COG0477	Major facilitator Superfamily
D9782_RS15760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9782_RS15765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9782_RS15775	COG0022	dehydrogenase e1 component
D9782_RS15780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9782_RS15785	COG3414	Phosphotransferase system galactitol-specific IIB component
D9782_RS15790	COG0235	Class ii aldolase
D9782_RS15795	COG3775	system Galactitol-specific IIC component
D9782_RS15850	COG2390	Transcriptional regulator
D9782_RS15865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9782_RS15870	COG0314	molybdopterin synthase activity
D9782_RS15875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9782_RS15880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9782_RS15895	COG2181	nitrate reductase activity
D9782_RS15900	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9782_RS15905	COG1140	nitrate reductase beta subunit
D9782_RS15910	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9782_RS15915	COG0535	radical SAM domain protein
D9782_RS15920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9782_RS15930	COG1999	signal sequence binding
D9782_RS15935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9782_RS15940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9782_RS15945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS15950	COG0785	Cytochrome C biogenesis protein
D9782_RS15965	COG1683	Conserved Protein
D9782_RS15980	COG0124	histidyl-tRNA synthetase
D9782_RS16025	COG4372	Transposase
D9782_RS16050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9782_RS16055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9782_RS16065	COG2801	Transposase and inactivated derivatives
D9782_RS16080	COG0586	Pfam SNARE associated Golgi protein
D9782_RS16110	COG2070	2-Nitropropane dioxygenase
D9782_RS16115	COG0583	DNA-binding transcription factor activity
D9782_RS16150	COG0659	secondary active sulfate transmembrane transporter activity
D9782_RS16155	COG3311	Transcriptional regulator
D9782_RS16195	COG0174	glutamine synthetase
D9782_RS16200	COG0789	Transcriptional regulator
D9782_RS16205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9782_RS16210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9782_RS16215	COG0464	growth
D9782_RS16220	COG1923	regulation of RNA biosynthetic process
D9782_RS16225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9782_RS16230	COG0783	Belongs to the Dps family
D9782_RS16235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9782_RS16240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9782_RS16250	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9782_RS16255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9782_RS16260	COG2359	stage V sporulation protein S
D9782_RS16265	COG1692	metallophosphoesterase
D9782_RS16270	COG1418	mRNA catabolic process
D9782_RS16275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9782_RS16280	COG1058	Belongs to the CinA family
D9782_RS16280	COG1546	Belongs to the CinA family
D9782_RS16285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9782_RS16290	COG1426	Protein conserved in bacteria
D9782_RS16305	COG0300	oxidoreductase activity
D9782_RS16310	COG0612	Peptidase, M16
D9782_RS16315	COG0612	Peptidase, M16
D9782_RS16320	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9782_RS16325	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9782_RS16330	COG3845	ABC transporter
D9782_RS16335	COG1744	ABC transporter substrate-binding protein PnrA-like
D9782_RS16340	COG2188	Transcriptional regulator
D9782_RS16345	COG1674	ftsk spoiiie
D9782_RS16355	COG0740	serine-type endopeptidase activity
D9782_RS16360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9782_RS16365	COG0527	aspartate kinase activity
D9782_RS16370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9782_RS16375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9782_RS16380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9782_RS16395	COG0612	Peptidase, M16
D9782_RS16400	COG0726	polysaccharide deacetylase
D9782_RS16405	COG1185	polyribonucleotide nucleotidyltransferase activity
D9782_RS16410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9782_RS16415	COG0196	riboflavin kinase activity
D9782_RS16420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9782_RS16425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9782_RS16430	COG1550	Protein conserved in bacteria
D9782_RS16435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9782_RS16445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9782_RS16450	COG0195	Participates in both transcription termination and antitermination
D9782_RS16455	COG0779	Required for maturation of 30S ribosomal subunits
D9782_RS16460	COG2176	DNA-directed DNA polymerase activity
D9782_RS16465	COG0750	zinc metalloprotease
D9782_RS16470	COG4589	Belongs to the CDS family
D9782_RS16475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9782_RS16480	COG0233	cytoplasmic translational termination
D9782_RS16485	COG0528	UMP kinase activity
D9782_RS16490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9782_RS16495	COG0052	Belongs to the universal ribosomal protein uS2 family
D9782_RS16515	COG1191	sigma factor activity
D9782_RS16520	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9782_RS16525	COG1776	CheC inhibitor of MCP methylation
D9782_RS16530	COG0835	chemotaxis
D9782_RS16535	COG2198	Histidine kinase
D9782_RS16535	COG0643	Histidine kinase
D9782_RS16540	COG2201	protein-glutamate methylesterase activity
D9782_RS16545	COG0455	bacterial-type flagellum organization
D9782_RS16550	COG1419	protein localization to endoplasmic reticulum
D9782_RS16555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9782_RS16560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9782_RS16565	COG1684	flagellar biosynthetic protein fliR
D9782_RS16570	COG1987	bacterial-type flagellum assembly
D9782_RS16575	COG1338	Plays a role in the flagellum-specific transport system
D9782_RS16580	COG3190	flagellar
D9782_RS16585	COG2201	protein-glutamate methylesterase activity
D9782_RS16590	COG1776	CheC inhibitor of MCP methylation
D9782_RS16590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9782_RS16595	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9782_RS16600	COG1580	Controls the rotational direction of flagella during chemotaxis
D9782_RS16605	COG1582	Flagellar protein (FlbD)
D9782_RS16610	COG4786	Flagellar basal body rod
D9782_RS16620	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9782_RS16640	COG1157	protein secretion by the type III secretion system
D9782_RS16645	COG1317	bacterial-type flagellum organization
D9782_RS16650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9782_RS16655	COG1766	The M ring may be actively involved in energy transduction
D9782_RS16660	COG1677	Flagellar hook-basal body complex protein FliE
D9782_RS16665	COG1558	bacterial-type flagellum-dependent cell motility
D9782_RS16670	COG1815	bacterial-type flagellum-dependent cell motility
D9782_RS16675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9782_RS16680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9782_RS16685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9782_RS16690	COG4974	Belongs to the 'phage' integrase family
D9782_RS16700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9782_RS16705	COG0758	DNA mediated transformation
D9782_RS16710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9782_RS16715	COG0045	succinate-CoA ligase (ADP-forming) activity
D9782_RS16720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9782_RS16730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9782_RS16745	COG0335	large ribosomal subunit rRNA binding
D9782_RS16750	COG0336	Belongs to the RNA methyltransferase TrmD family
D9782_RS16755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9782_RS16765	COG1837	Belongs to the UPF0109 family
D9782_RS16770	COG0228	four-way junction DNA binding
D9782_RS16775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9782_RS16780	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9782_RS16785	COG0552	protein localization to endoplasmic reticulum
D9782_RS16790	COG1196	nuclear chromosome segregation
D9782_RS16795	COG4840	Belongs to the UPF0435 family
D9782_RS16800	COG0571	ribonuclease III activity
D9782_RS16805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9782_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS16815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9782_RS16820	COG0416	fatty acid biosynthetic process
D9782_RS16825	COG1349	DNA-binding transcription factor activity
D9782_RS16830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9782_RS16835	COG1760	l-serine dehydratase
D9782_RS16840	COG1760	l-serine dehydratase
D9782_RS16855	COG1461	Dihydroxyacetone kinase
D9782_RS16860	COG1302	Protein conserved in bacteria
D9782_RS16865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9782_RS16875	COG1564	THIamine pyrophosphokinase
D9782_RS16880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9782_RS16885	COG1162	GTPase activity
D9782_RS16890	COG2815	serine threonine protein kinase
D9782_RS16890	COG0515	serine threonine protein kinase
D9782_RS16895	COG0631	protein serine/threonine phosphatase activity
D9782_RS16900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9782_RS16900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9782_RS16905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9782_RS16910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9782_RS16915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9782_RS16920	COG1758	RNA polymerase activity
D9782_RS16925	COG0194	GDP metabolic process
D9782_RS16930	COG2052	Domain of unknown function (DUF370)
D9782_RS16935	COG1561	YicC-like family, N-terminal region
D9782_RS16940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9782_RS16950	COG1764	response to oxidative stress
D9782_RS16960	COG2226	methyltransferase
D9782_RS16965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9782_RS16970	COG0006	proline dipeptidase activity
D9782_RS16985	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9782_RS17000	COG2801	Transposase and inactivated derivatives
D9782_RS17005	COG2801	Transposase and inactivated derivatives
D9782_RS17010	COG1321	iron dependent repressor
D9782_RS17015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS17020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9782_RS17025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9782_RS17030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9782_RS17035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9782_RS17050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9782_RS17055	COG1459	type II secretion system
D9782_RS17060	COG4537	Required for transformation and DNA binding
D9782_RS17090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS17105	COG1368	sulfuric ester hydrolase activity
D9782_RS17110	COG1940	carbohydrate kinase activity
D9782_RS17130	COG0697	spore germination
D9782_RS17140	COG0705	Rhomboid family
D9782_RS17140	COG0457	Tetratricopeptide repeat
D9782_RS17150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9782_RS17155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9782_RS17160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9782_RS17210	COG0704	Plays a role in the regulation of phosphate uptake
D9782_RS17215	COG0768	penicillin binding
D9782_RS17220	COG0477	Major facilitator Superfamily
D9782_RS17225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9782_RS17260	COG0704	Plays a role in the regulation of phosphate uptake
D9782_RS17265	COG1030	water channel activity
D9782_RS17275	COG4709	membrane
D9782_RS17285	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9782_RS17295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9782_RS17300	COG2384	SAM-dependent methyltransferase
D9782_RS17315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9782_RS17320	COG0358	DNA primase activity
D9782_RS17325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9782_RS17330	COG0517	IMP dehydrogenase activity
D9782_RS17335	COG0751	glycine-tRNA ligase activity
D9782_RS17340	COG0752	glycyl-tRNA synthetase alpha subunit
D9782_RS17345	COG1381	Involved in DNA repair and RecF pathway recombination
D9782_RS17355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9782_RS17360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9782_RS17365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9782_RS17370	COG1480	7TM receptor with intracellular HD hydrolase
D9782_RS17375	COG1702	phosphate starvation-inducible protein PhoH
D9782_RS17395	COG4864	UPF0365 protein
D9782_RS17400	COG1030	water channel activity
D9782_RS17405	COG1610	YqeY-like protein
D9782_RS17410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9782_RS17415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9782_RS17420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9782_RS17425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9782_RS17430	COG2264	protein methyltransferase activity
D9782_RS17435	COG0484	heat shock protein binding
D9782_RS17440	COG0443	Heat shock 70 kDa protein
D9782_RS17445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9782_RS17450	COG1420	regulation of RNA biosynthetic process
D9782_RS17455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9782_RS17470	COG0481	GTPase activity
D9782_RS17480	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS17485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9782_RS17490	COG0268	Binds directly to 16S ribosomal RNA
D9782_RS17495	COG1466	dna polymerase III delta subunit
D9782_RS17505	COG0658	competence protein
D9782_RS17505	COG2333	competence protein COMEC
D9782_RS17510	COG2131	deaminase
D9782_RS17515	COG1596	polysaccharide export
D9782_RS17515	COG1555	photosystem II stabilization
D9782_RS17520	COG2226	methyltransferase
D9782_RS17525	COG0799	negative regulation of ribosome biogenesis
D9782_RS17530	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9782_RS17535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9782_RS17540	COG1534	Rna-binding protein
D9782_RS17545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9782_RS17550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9782_RS17555	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9782_RS17565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9782_RS17565	COG2111	Na H antiporter
D9782_RS17570	COG1006	Multisubunit Na H antiporter MnhC subunit
D9782_RS17575	COG0651	ATP synthesis coupled electron transport
D9782_RS17580	COG1863	multisubunit Na H antiporter MnhE subunit
D9782_RS17585	COG2212	antiporter activity
D9782_RS17590	COG1320	monovalent cation:proton antiporter activity
D9782_RS17595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9782_RS17605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9782_RS17625	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9782_RS17625	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS17815	COG0629	single-stranded DNA binding
D9782_RS17850	COG0305	Participates in initiation and elongation during chromosome replication
D9782_RS17955	COG3646	Phage regulatory protein
D9782_RS17955	COG3645	SOS response
D9782_RS17985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9782_RS17995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9782_RS18000	COG0572	uridine kinase
D9782_RS18005	COG4122	O-methyltransferase activity
D9782_RS18010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9782_RS18015	COG3906	Belongs to the UPF0473 family
D9782_RS18020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9782_RS18025	COG4472	Bacterial protein of unknown function (DUF965)
D9782_RS18030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9782_RS18055	COG0628	permease
D9782_RS18065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9782_RS18075	COG0482	sulfurtransferase activity
D9782_RS18080	COG1104	cysteine desulfurase activity
D9782_RS18085	COG1959	2 iron, 2 sulfur cluster binding
D9782_RS18090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9782_RS18105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9782_RS18110	COG0124	histidyl-tRNA synthetase
D9782_RS18115	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9782_RS18120	COG1490	D-aminoacyl-tRNA deacylase activity
D9782_RS18125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9782_RS18130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9782_RS18135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9782_RS18135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9782_RS18140	COG5416	Lipopolysaccharide assembly protein A domain
D9782_RS18145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9782_RS18145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9782_RS18155	COG2244	polysaccharide biosynthetic process
D9782_RS18170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9782_RS18180	COG1862	Preprotein translocase
D9782_RS18185	COG0343	queuine tRNA-ribosyltransferase activity
D9782_RS18190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9782_RS18200	COG2255	four-way junction helicase activity
D9782_RS18205	COG0632	four-way junction helicase activity
D9782_RS18210	COG0217	transcriptional regulatory protein
D9782_RS18220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9782_RS18235	COG0077	Prephenate dehydratase
D9782_RS18240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9782_RS18250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9782_RS18255	COG2868	ribosomal protein
D9782_RS18260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9782_RS18270	COG0662	Cupin 2, conserved barrel domain protein
D9782_RS18275	COG0673	inositol 2-dehydrogenase activity
D9782_RS18285	COG1098	S1 RNA binding domain
D9782_RS18290	COG1994	Peptidase M50
D9782_RS18300	COG2894	cell division
D9782_RS18305	COG0850	regulation of cytokinetic process
D9782_RS18320	COG1077	Cell shape determining protein MreB Mrl
D9782_RS18365	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9782_RS18365	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS18440	COG0740	serine-type endopeptidase activity
D9782_RS18450	COG1802	Transcriptional regulator
D9782_RS18450	COG4626	Terminase
D9782_RS18470	COG3677	Transposase
D9782_RS18550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9782_RS18630	COG0582	viral genome integration into host DNA
D9782_RS18635	COG2003	Belongs to the UPF0758 family
D9782_RS18645	COG0285	dihydrofolate synthase activity
D9782_RS18660	COG0525	valine-tRNA ligase activity
D9782_RS18675	COG1388	LysM domain
D9782_RS18675	COG1388	LysM domain
D9782_RS18685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9782_RS18690	COG0113	porphobilinogen synthase activity
D9782_RS18695	COG1587	Uroporphyrinogen-III synthase
D9782_RS18700	COG0181	hydroxymethylbilane synthase activity
D9782_RS18705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9782_RS18710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9782_RS18720	COG1126	abc transporter atp-binding protein
D9782_RS18725	COG0765	amino acid transport
D9782_RS18730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9782_RS18735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9782_RS18745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9782_RS18750	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9782_RS18755	COG0457	Tetratricopeptide repeat
D9782_RS18755	COG1477	protein flavinylation
D9782_RS18790	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS18790	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9782_RS18805	COG0622	Phosphoesterase
D9782_RS18810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9782_RS18815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9782_RS18825	COG5401	PFAM Sporulation and spore germination
D9782_RS18830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9782_RS18835	COG1846	Transcriptional regulator
D9782_RS18840	COG2197	response regulator
D9782_RS18845	COG0824	Thioesterase
D9782_RS18850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9782_RS18855	COG1053	succinate dehydrogenase
D9782_RS18860	COG2009	succinate dehydrogenase
D9782_RS18865	COG1719	4-vinyl reductase, 4VR
D9782_RS18870	COG0322	excinuclease ABC activity
D9782_RS18875	COG3118	belongs to the thioredoxin family
D9782_RS18880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9782_RS18885	COG2086	electron transfer activity
D9782_RS18890	COG1024	Enoyl-CoA hydratase
D9782_RS18895	COG1309	transcriptional regulator
D9782_RS18900	COG0318	PFAM AMP-dependent synthetase and ligase
D9782_RS18905	COG3766	membrane
D9782_RS18910	COG1193	negative regulation of DNA recombination
D9782_RS18915	COG1796	DNA polymerase
D9782_RS18915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9782_RS18920	COG1286	toxin biosynthetic process
D9782_RS18925	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9782_RS18930	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9782_RS18935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9782_RS18935	COG0072	phenylalanine-tRNA ligase activity
D9782_RS18940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9782_RS18945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9782_RS18970	COG1131	(ABC) transporter
D9782_RS18975	COG0741	lytic transglycosylase activity
D9782_RS18985	COG2801	Transposase and inactivated derivatives
D9782_RS18995	COG1363	Peptidase, m42
D9782_RS19010	COG0398	Pfam SNARE associated Golgi protein
D9782_RS19015	COG3326	Membrane
D9782_RS19020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9782_RS19025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9782_RS19030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9782_RS19045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9782_RS19055	COG1605	Chorismate mutase
D9782_RS19055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9782_RS19065	COG3251	PFAM MbtH domain protein
D9782_RS19070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9782_RS19075	COG1535	isochorismatase
D9782_RS19075	COG3433	isochorismatase activity
D9782_RS19080	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9782_RS19085	COG1169	isochorismate synthase
D9782_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS19105	COG1484	DNA-dependent DNA replication
D9782_RS19110	COG3611	Membrane attachment protein
D9782_RS19115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9782_RS19125	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9782_RS19130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9782_RS19135	COG0237	dephospho-CoA kinase activity
D9782_RS19140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9782_RS19145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9782_RS19145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9782_RS19150	COG5002	protein histidine kinase activity
D9782_RS19155	COG0745	RESPONSE REGULATOR receiver
D9782_RS19165	COG0039	L-malate dehydrogenase activity
D9782_RS19170	COG0538	isocitrate dehydrogenase activity
D9782_RS19175	COG0372	Belongs to the citrate synthase family
D9782_RS19180	COG0628	permease
D9782_RS19185	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9782_RS19195	COG0205	6-phosphofructokinase activity
D9782_RS19200	COG0825	malonyl-CoA metabolic process
D9782_RS19205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9782_RS19215	COG0281	malic enzyme
D9782_RS19220	COG0587	DNA-directed DNA polymerase activity
D9782_RS19240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9782_RS19250	COG4109	DRTGG domain
D9782_RS19260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9782_RS19265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9782_RS19270	COG0006	proline dipeptidase activity
D9782_RS19280	COG0589	response to stress
D9782_RS19285	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9782_RS19290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9782_RS19295	COG0827	DNA restriction-modification system
D9782_RS19300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9782_RS19305	COG3874	Sporulation protein YtfJ
D9782_RS19315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9782_RS19330	COG0301	tRNA thio-modification
D9782_RS19335	COG1104	cysteine desulfurase activity
D9782_RS19340	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9782_RS19345	COG1309	transcriptional regulator
D9782_RS19350	COG1956	GAF domain-containing protein
D9782_RS19355	COG2199	diguanylate cyclase activity
D9782_RS19355	COG2203	Gaf domain
D9782_RS19360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9782_RS19365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9782_RS19370	COG3002	Belongs to the UPF0753 family
D9782_RS19375	COG0288	reversible hydration of carbon dioxide
D9782_RS19385	COG5609	conserved protein (DUF2294)
D9782_RS19405	COG1288	antiporter activity
D9782_RS19410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9782_RS19425	COG0454	-acetyltransferase
D9782_RS19430	COG0517	IMP dehydrogenase activity
D9782_RS19435	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9782_RS19450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9782_RS19460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9782_RS19460	COG1605	Chorismate mutase
D9782_RS19475	COG4980	gas vesicle protein
D9782_RS19490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9782_RS19500	COG1674	ftsk spoiiie
D9782_RS19505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9782_RS19510	COG4848	Belongs to the UPF0354 family
D9782_RS19515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS19530	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D9782_RS19535	COG1363	Peptidase, m42
D9782_RS19545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9782_RS19550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9782_RS19560	COG0510	thiamine kinase activity
D9782_RS19575	COG1187	pseudouridine synthase activity
D9782_RS19580	COG2244	polysaccharide biosynthetic process
D9782_RS19585	COG2081	HI0933 family
D9782_RS19595	COG1876	peptidase activity
D9782_RS19720	COG3728	DNA packaging
D9782_RS19730	COG1595	DNA-templated transcription, initiation
D9782_RS19740	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D9782_RS19815	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9782_RS19865	COG3646	Phage regulatory protein
D9782_RS19865	COG3645	SOS response
D9782_RS19890	COG2856	Zn peptidase
D9782_RS19935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9782_RS19950	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9782_RS19960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9782_RS19965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9782_RS19970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9782_RS19980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9782_RS19985	COG1116	anion transmembrane transporter activity
D9782_RS19990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9782_RS19995	COG0494	nUDIX hydrolase
D9782_RS20010	COG1120	ATPase activity
D9782_RS20015	COG0318	PFAM AMP-dependent synthetase and ligase
D9782_RS20020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9782_RS20025	COG0596	Alpha beta hydrolase
D9782_RS20030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9782_RS20035	COG1169	isochorismate synthase
D9782_RS20040	COG1575	Belongs to the MenA family. Type 1 subfamily
D9782_RS20045	COG2050	protein possibly involved in aromatic compounds catabolism
D9782_RS20050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9782_RS20065	COG1404	Belongs to the peptidase S8 family
D9782_RS20065	COG4412	M6 family metalloprotease domain protein
D9782_RS20085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9782_RS20095	COG1098	S1 RNA binding domain
D9782_RS20100	COG2155	Conserved Protein
D9782_RS20110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9782_RS20115	COG2032	superoxide dismutase activity
D9782_RS20130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS20135	COG0813	purine-nucleoside phosphorylase activity
D9782_RS20140	COG1268	BioY protein
D9782_RS20145	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9782_RS20150	COG3584	3D domain protein
D9782_RS20160	COG1252	NADH dehydrogenase
D9782_RS20165	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS20170	COG0316	Belongs to the HesB IscA family
D9782_RS20175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9782_RS20180	COG4837	Protein of unknown function (DUF1462)
D9782_RS20185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9782_RS20190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9782_RS20195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9782_RS20200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9782_RS20205	COG0647	UMP catabolic process
D9782_RS20215	COG2445	Protein of unknown function DUF86
D9782_RS20225	COG0154	amidase activity
D9782_RS20235	COG4470	Protein conserved in bacteria
D9782_RS20245	COG0739	heme binding
D9782_RS20255	COG0733	neurotransmitter:sodium symporter activity
D9782_RS20260	COG1757	Na H antiporter
D9782_RS20275	COG3377	Domain of unknown function (DUF1805)
D9782_RS20280	COG0737	Belongs to the 5'-nucleotidase family
D9782_RS20285	COG0730	response to heat
D9782_RS20290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9782_RS20295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9782_RS20300	COG0561	phosphatase activity
D9782_RS20325	COG2723	6-phospho-beta-galactosidase activity
D9782_RS20335	COG0383	alpha-mannosidase activity
D9782_RS20345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS20345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS20345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9782_RS20385	COG0367	asparagine synthase
D9782_RS20450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9782_RS20450	COG0456	acetyltransferase
D9782_RS20475	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9782_RS20475	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS20520	COG4974	Belongs to the 'phage' integrase family
D9782_RS20525	COG0719	Fe-S assembly protein
D9782_RS20530	COG0822	iron-sulfur transferase activity
D9782_RS20535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9782_RS20540	COG0719	Fe-S assembly protein
D9782_RS20545	COG0396	ATPase activity
D9782_RS20550	COG1464	Belongs to the NlpA lipoprotein family
D9782_RS20555	COG2011	ABC-type metal ion transport system permease component
D9782_RS20560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9782_RS20565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9782_RS20570	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9782_RS20575	COG0509	glycine decarboxylation via glycine cleavage system
D9782_RS20580	COG1393	Belongs to the ArsC family
D9782_RS20590	COG1960	acyl-CoA dehydrogenase activity
D9782_RS20595	COG0183	Belongs to the thiolase family
D9782_RS20600	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9782_RS20600	COG1024	Enoyl-CoA hydratase
D9782_RS20615	COG1121	(ABC) transporter
D9782_RS20620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9782_RS20625	COG0735	belongs to the Fur family
D9782_RS20630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9782_RS20635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9782_RS20650	COG2076	Multidrug Resistance protein
D9782_RS20655	COG2076	Multidrug Resistance protein
D9782_RS20660	COG1253	flavin adenine dinucleotide binding
D9782_RS20670	COG0791	NLP P60 protein
D9782_RS20670	COG3883	PFAM NLP P60 protein
D9782_RS20670	COG0791	NLP P60 protein
D9782_RS20670	COG3883	PFAM NLP P60 protein
D9782_RS20675	COG2224	Isocitrate lyase
D9782_RS20680	COG4129	membrane
D9782_RS20685	COG2197	response regulator
D9782_RS20695	COG4758	membrane
D9782_RS20725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9782_RS20740	COG1363	Peptidase, m42
D9782_RS20755	COG0517	IMP dehydrogenase activity
D9782_RS20765	COG1657	PFAM Prenyltransferase squalene oxidase
D9782_RS20775	COG2197	response regulator
D9782_RS20795	COG3279	Response regulator of the LytR AlgR family
D9782_RS20800	COG0745	RESPONSE REGULATOR receiver
D9782_RS20800	COG2972	Histidine kinase
D9782_RS20805	COG0109	protoheme IX farnesyltransferase activity
D9782_RS20830	COG0640	Transcriptional regulator
D9782_RS20835	COG0604	alcohol dehydrogenase
D9782_RS20840	COG2972	Histidine kinase
D9782_RS20840	COG0745	RESPONSE REGULATOR receiver
D9782_RS20855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9782_RS20860	COG0557	exoribonuclease II activity
D9782_RS20865	COG1647	Serine aminopeptidase, S33
D9782_RS20870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9782_RS20885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9782_RS20895	COG0084	hydrolase, TatD family'
D9782_RS20900	COG1116	anion transmembrane transporter activity
D9782_RS20905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9782_RS20915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9782_RS20920	COG0148	phosphopyruvate hydratase activity
D9782_RS20925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9782_RS20930	COG0149	triose-phosphate isomerase activity
D9782_RS20935	COG0126	phosphoglycerate kinase activity
D9782_RS20940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9782_RS20955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9782_RS20960	COG0328	RNA-DNA hybrid ribonuclease activity
D9782_RS20965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9782_RS20970	COG3162	membrane
D9782_RS20980	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9782_RS20985	COG2112	serine threonine protein kinase
D9782_RS20990	COG2610	gluconate transmembrane transporter activity
D9782_RS20995	COG0183	Belongs to the thiolase family
D9782_RS21000	COG1028	Short-chain dehydrogenase reductase Sdr
D9782_RS21005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9782_RS21010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9782_RS21020	COG0710	3-dehydroquinate dehydratase activity
D9782_RS21025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9782_RS21045	COG2124	cytochrome p450
D9782_RS21055	COG0740	serine-type endopeptidase activity
D9782_RS21060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9782_RS21065	COG1481	regulation of sporulation
D9782_RS21070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9782_RS21075	COG1660	Displays ATPase and GTPase activities
D9782_RS21080	COG1051	belongs to the nudix hydrolase family
D9782_RS21085	COG0492	ferredoxin-NADP+ reductase activity
D9782_RS21090	COG0457	Tetratricopeptide repeat
D9782_RS21095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9782_RS21100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9782_RS21105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9782_RS21110	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9782_RS21115	COG0110	maltose O-acetyltransferase activity
D9782_RS21120	COG0546	phosphoglycolate phosphatase activity
D9782_RS21125	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9782_RS21130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9782_RS21135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9782_RS21140	COG1950	PFAM Membrane protein of
D9782_RS21145	COG1983	PspC domain protein
D9782_RS21155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9782_RS21160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9782_RS21165	COG0556	nucleotide-excision repair
D9782_RS21175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9782_RS21180	COG0726	polysaccharide deacetylase
D9782_RS21190	COG5578	integral membrane protein
D9782_RS21195	COG0395	ABC-type sugar transport system, permease component
D9782_RS21200	COG1175	transmembrane transport
D9782_RS21210	COG2207	Transcriptional regulator
D9782_RS21210	COG4753	response regulator
D9782_RS21215	COG2972	Histidine kinase
D9782_RS21230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9782_RS21235	COG3409	Peptidoglycan-binding domain 1 protein
D9782_RS21235	COG0793	Belongs to the peptidase S41A family
D9782_RS21240	COG0739	heme binding
D9782_RS21245	COG2177	Part of the ABC transporter FtsEX involved in
D9782_RS21250	COG2884	Cell division ATP-binding protein ftsE
D9782_RS21265	COG0653	protein targeting
D9782_RS21270	COG3634	alkyl hydroperoxide reductase activity
D9782_RS21275	COG0450	alkyl hydroperoxide reductase
D9782_RS21290	COG1516	flagellar protein fliS
D9782_RS21295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9782_RS21300	COG1334	flagellar protein FlaG
D9782_RS21305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9782_RS21310	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9782_RS21320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9782_RS21325	COG4786	Flagellar basal body rod
D9782_RS21325	COG1256	bacterial-type flagellum assembly
D9782_RS21345	COG1040	competence protein
D9782_RS21350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9782_RS21355	COG1307	EDD domain protein, DegV family
D9782_RS21360	COG2197	response regulator
D9782_RS21370	COG1739	Uncharacterized protein family UPF0029
D9782_RS21375	COG0363	glucosamine-6-phosphate deaminase activity
D9782_RS21380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9782_RS21385	COG1396	sequence-specific DNA binding
D9782_RS21395	COG1316	TRANSCRIPTIONal
D9782_RS21400	COG0768	penicillin binding
D9782_RS21415	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS21425	COG0561	phosphatase activity
D9782_RS21430	COG2814	Major facilitator Superfamily
D9782_RS21435	COG1984	allophanate hydrolase subunit 2
D9782_RS21440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9782_RS21445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9782_RS21450	COG0471	metal ion transport
D9782_RS21460	COG2807	transmembrane transport
D9782_RS21475	COG1368	sulfuric ester hydrolase activity
D9782_RS21480	COG0840	transmembrane signaling receptor activity
D9782_RS21485	COG1360	Flagellar Motor Protein
D9782_RS21490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9782_RS21495	COG0840	transmembrane signaling receptor activity
D9782_RS21500	COG1012	belongs to the aldehyde dehydrogenase family
D9782_RS21505	COG2089	acid synthase
D9782_RS21515	COG1083	cytidylyl-transferase
D9782_RS21540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9782_RS21545	COG2031	fatty acid transporter
D9782_RS21550	COG0596	Alpha beta hydrolase
D9782_RS21555	COG0697	spore germination
D9782_RS21570	COG0010	Belongs to the arginase family
D9782_RS21575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9782_RS21595	COG3876	Protein conserved in bacteria
D9782_RS21600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9782_RS21610	COG0681	Belongs to the peptidase S26 family
D9782_RS21620	COG1472	Belongs to the glycosyl hydrolase 3 family
D9782_RS21630	COG0395	ABC-type sugar transport system, permease component
D9782_RS21635	COG1175	transmembrane transport
D9782_RS21655	COG1737	Transcriptional regulator
D9782_RS21660	COG2971	BadF BadG BcrA BcrD
D9782_RS21665	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9782_RS21675	COG1737	Transcriptional regulator
D9782_RS21680	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9782_RS21685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9782_RS21685	COG1263	PTS System
D9782_RS21695	COG1486	melibiose metabolic process
D9782_RS21700	COG1609	Transcriptional regulator
D9782_RS21705	COG3833	ABC-type maltose transport systems, permease component
D9782_RS21710	COG1175	transmembrane transport
D9782_RS21715	COG2182	Extracellular solute-binding protein
D9782_RS21725	COG5583	Uncharacterized small protein (DUF2292)
D9782_RS21730	COG0646	methionine synthase
D9782_RS21730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9782_RS21735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9782_RS21760	COG0165	Argininosuccinate lyase
D9782_RS21770	COG3842	ATPase activity
D9782_RS21775	COG1840	ABC-type Fe3 transport system, periplasmic component
D9782_RS21780	COG1940	carbohydrate kinase activity
D9782_RS21795	COG3546	catalase activity
D9782_RS21800	COG1331	Highly conserved protein containing a thioredoxin domain
D9782_RS21810	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D9782_RS21815	COG1473	amidohydrolase
D9782_RS21820	COG1473	amidohydrolase
D9782_RS21835	COG1971	Probably functions as a manganese efflux pump
D9782_RS21840	COG2996	Protein conserved in bacteria
D9782_RS21870	COG0745	RESPONSE REGULATOR receiver
D9782_RS21880	COG1494	fructose-1,6-bisphosphatase
D9782_RS21885	COG0698	ribose 5-phosphate isomerase
D9782_RS21895	COG2376	Dihydroxyacetone kinase
D9782_RS21900	COG2814	Major facilitator Superfamily
D9782_RS21905	COG1063	alcohol dehydrogenase
D9782_RS21910	COG1349	DNA-binding transcription factor activity
D9782_RS21915	COG0561	phosphatase activity
D9782_RS21920	COG2059	Chromate
D9782_RS21925	COG2059	Chromate
D9782_RS21955	COG4565	transcriptional regulatory protein
D9782_RS21960	COG3290	protein histidine kinase activity
D9782_RS21965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9782_RS21970	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
D9782_RS21975	COG1461	Dihydroxyacetone kinase
D9782_RS21980	COG2376	Dihydroxyacetone kinase
D9782_RS21985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9782_RS21990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9782_RS22000	COG1737	Transcriptional regulator
D9782_RS22005	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
D9782_RS22015	COG2190	(PTS) system
D9782_RS22020	COG0367	asparagine synthase
D9782_RS22025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9782_RS22030	COG0601	transmembrane transport
D9782_RS22040	COG4608	Belongs to the ABC transporter superfamily
D9782_RS22045	COG0444	Belongs to the ABC transporter superfamily
D9782_RS22050	COG1960	acyl-CoA dehydrogenase activity
D9782_RS22055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9782_RS22065	COG0463	Glycosyl transferase, family 2
D9782_RS22070	COG0456	acetyltransferase
D9782_RS22075	COG2076	Multidrug Resistance protein
D9782_RS22080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9782_RS22115	COG1940	carbohydrate kinase activity
D9782_RS22125	COG5426	von Willebrand factor, type A
D9782_RS22130	COG0395	ABC-type sugar transport system, permease component
D9782_RS22145	COG1917	Cupin 2, conserved barrel domain protein
D9782_RS22145	COG2207	Transcriptional regulator
D9782_RS22155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9782_RS22160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9782_RS22165	COG0066	3-isopropylmalate dehydratase activity
D9782_RS22170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9782_RS22175	COG0473	3-isopropylmalate dehydrogenase activity
D9782_RS22180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9782_RS22185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9782_RS22190	COG0440	acetolactate synthase activity
D9782_RS22195	COG0028	Belongs to the TPP enzyme family
D9782_RS22200	COG0129	dihydroxy-acid dehydratase activity
D9782_RS22205	COG0656	L-ascorbic acid biosynthetic process
D9782_RS22220	COG1940	carbohydrate kinase activity
D9782_RS22225	COG1940	carbohydrate kinase activity
D9782_RS22325	COG1525	nuclease
D9782_RS22350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9782_RS22385	COG0551	DNA topoisomerase type I activity
D9782_RS22385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9782_RS22430	COG0741	lytic transglycosylase activity
D9782_RS22430	COG0791	NLP P60 protein
D9782_RS22515	COG1396	sequence-specific DNA binding
D9782_RS22520	COG1396	sequence-specific DNA binding
D9782_RS22575	COG1476	TRANSCRIPTIONal