locus-tag	class	description
VITFI_RS00020	COG2974	May be involved in recombination
VITFI_RS00075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_RS00095	COG2719	SpoVR family
VITFI_RS00100	COG2718	Belongs to the UPF0229 family
VITFI_RS00105	COG2766	serine protein kinase
VITFI_RS00115	COG1475	DNA binding
VITFI_RS00125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VITFI_RS00130	COG1192	Involved in chromosome partitioning
VITFI_RS00140	COG0357	Ribosomal RNA small subunit methyltransferase G
VITFI_RS00145	COG0445	tRNA wobble uridine modification
VITFI_RS00190	COG2197	response regulator
VITFI_RS00200	COG1668	transmembrane transport
VITFI_RS00205	COG1131	(ABC) transporter
VITFI_RS00215	COG0625	glutathione transferase activity
VITFI_RS00245	COG4181	ATPase activity
VITFI_RS00255	COG0803	Belongs to the bacterial solute-binding protein 9 family
VITFI_RS00265	COG1121	(ABC) transporter
VITFI_RS00275	COG0564	pseudouridine synthase activity
VITFI_RS00290	COG2199	diguanylate cyclase activity
VITFI_RS00290	COG2203	Gaf domain
VITFI_RS00345	COG0187	DNA topoisomerase II activity
VITFI_RS00355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VITFI_RS00360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VITFI_RS00365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VITFI_RS00370	COG0594	ribonuclease P activity
VITFI_RS00375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
VITFI_RS00380	COG0706	membrane insertase activity
VITFI_RS00385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VITFI_RS00395	COG0515	serine threonine protein kinase
VITFI_RS00395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_RS00400	COG1569	PIN domain
VITFI_RS00405	COG3311	Transcriptional regulator
VITFI_RS00410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VITFI_RS00545	COG4397	Mu-like prophage major head subunit gpT
VITFI_RS00575	COG4383	Mu-like prophage protein gp29
VITFI_RS00580	COG4373	Mu-like prophage FluMu protein gp28
VITFI_RS00655	COG2974	May be involved in recombination
VITFI_RS00705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_RS00735	COG3845	ABC transporter
VITFI_RS00740	COG0402	S-adenosylhomocysteine deaminase activity
VITFI_RS00755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
VITFI_RS00765	COG0730	response to heat
VITFI_RS00805	COG1172	Belongs to the binding-protein-dependent transport system permease family
VITFI_RS00835	COG2198	Histidine kinase
VITFI_RS00835	COG0784	Response regulator, receiver
VITFI_RS00835	COG2205	protein histidine kinase activity
VITFI_RS00840	COG2974	May be involved in recombination
VITFI_RS00845	COG0653	protein targeting
VITFI_RS00850	COG0739	heme binding
VITFI_RS00865	COG2969	positive regulation of protein catabolic process
VITFI_RS00870	COG0625	glutathione transferase activity
VITFI_RS00875	COG2857	Cytochrome c1
VITFI_RS00880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VITFI_RS00885	COG0723	plastoquinol--plastocyanin reductase activity
VITFI_RS00890	COG1970	mechanosensitive ion channel activity
VITFI_RS00895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VITFI_RS00900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VITFI_RS00905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_RS00910	COG0805	protein transport
VITFI_RS00915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VITFI_RS00920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VITFI_RS00925	COG0537	adenosine 5'-monophosphoramidase activity
VITFI_RS00930	COG0140	phosphoribosyl-ATP diphosphatase activity
VITFI_RS00935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VITFI_RS00940	COG0494	nUDIX hydrolase
VITFI_RS00950	COG1309	transcriptional regulator
VITFI_RS00960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VITFI_RS00990	COG3181	Tripartite tricarboxylate transporter family receptor
VITFI_RS01015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
VITFI_RS01020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_RS01030	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS01040	COG1301	dicarboxylic acid transport
VITFI_RS01045	COG2885	chlorophyll binding
VITFI_RS01055	COG1192	Involved in chromosome partitioning
VITFI_RS01060	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VITFI_RS01065	COG2894	cell division
VITFI_RS01070	COG0850	regulation of cytokinetic process
VITFI_RS01075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VITFI_RS01080	COG2354	Protein conserved in bacteria
VITFI_RS01085	COG1305	Transglutaminase-like
VITFI_RS01090	COG2308	Evidence 4 Homologs of previously reported genes of
VITFI_RS01090	COG2307	Protein conserved in bacteria
VITFI_RS01105	COG2308	Evidence 4 Homologs of previously reported genes of
VITFI_RS01150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_RS01170	COG1253	flavin adenine dinucleotide binding
VITFI_RS01175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VITFI_RS01205	COG0717	Belongs to the dCTP deaminase family
VITFI_RS01235	COG2824	Alkylphosphonate utilization operon protein PhnA
VITFI_RS01250	COG0569	domain protein
VITFI_RS01255	COG4651	solute:proton antiporter activity
VITFI_RS01255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VITFI_RS01265	COG0688	phosphatidylethanolamine metabolic process
VITFI_RS01280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VITFI_RS01285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
VITFI_RS01290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VITFI_RS01295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VITFI_RS01300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VITFI_RS01305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_RS01305	COG0072	phenylalanine-tRNA ligase activity
VITFI_RS01310	COG0776	regulation of translation
VITFI_RS01325	COG0745	RESPONSE REGULATOR receiver
VITFI_RS01345	COG4977	sequence-specific DNA binding
VITFI_RS01355	COG0166	Belongs to the GPI family
VITFI_RS01360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VITFI_RS01365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VITFI_RS01370	COG0837	glucose binding
VITFI_RS01370	COG1737	Transcriptional regulator
VITFI_RS01385	COG2853	Lipoprotein
VITFI_RS01390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VITFI_RS01395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VITFI_RS01400	COG1127	ABC transporter
VITFI_RS01410	COG0070	glutamate synthase
VITFI_RS01410	COG0067	glutamate synthase
VITFI_RS01410	COG0069	glutamate synthase activity
VITFI_RS01420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VITFI_RS01425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VITFI_RS01465	COG1965	Belongs to the frataxin family
VITFI_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS01480	COG0826	peptidase U32
VITFI_RS01505	COG3284	Transcriptional regulator
VITFI_RS01510	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_RS01530	COG2925	Exonuclease
VITFI_RS01545	COG3383	formate dehydrogenase (NAD+) activity
VITFI_RS01570	COG3634	alkyl hydroperoxide reductase activity
VITFI_RS01575	COG2319	Wd-40 repeat
VITFI_RS01575	COG1672	PFAM Archaeal ATPase
VITFI_RS01580	COG1672	PFAM Archaeal ATPase
VITFI_RS01580	COG2319	Wd-40 repeat
VITFI_RS01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_RS01595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VITFI_RS01615	COG0243	molybdopterin cofactor binding
VITFI_RS01620	COG1278	Cold shock
VITFI_RS01630	COG1473	amidohydrolase
VITFI_RS01635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VITFI_RS01640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VITFI_RS01645	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
VITFI_RS01655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VITFI_RS01670	COG0588	phosphoglycerate mutase activity
VITFI_RS01675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VITFI_RS01685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VITFI_RS01690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VITFI_RS01695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VITFI_RS01700	COG1040	competence protein
VITFI_RS01705	COG2226	methyltransferase
VITFI_RS01710	COG1999	signal sequence binding
VITFI_RS01715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_RS01735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_RS01745	COG1024	Enoyl-CoA hydratase
VITFI_RS01750	COG0583	DNA-binding transcription factor activity
VITFI_RS01830	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_RS01850	COG3058	Necessary for formate dehydrogenase activity
VITFI_RS01855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VITFI_RS01860	COG2864	formate dehydrogenase
VITFI_RS01865	COG0437	4 iron, 4 sulfur cluster binding
VITFI_RS01870	COG3383	formate dehydrogenase (NAD+) activity
VITFI_RS01870	COG0243	molybdopterin cofactor binding
VITFI_RS01880	COG3852	Histidine kinase
VITFI_RS01885	COG1072	(Pantothenic acid kinase))
VITFI_RS01895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VITFI_RS01920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VITFI_RS01920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VITFI_RS01925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VITFI_RS01935	COG3300	MHYT domain
VITFI_RS01935	COG5001	Diguanylate cyclase
VITFI_RS01940	COG3706	GGDEF domain
VITFI_RS01950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VITFI_RS01960	COG1203	CRISPR-associated helicase, Cas3
VITFI_RS01985	COG1857	crispr-associated protein
VITFI_RS02000	COG1518	maintenance of DNA repeat elements
VITFI_RS02005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_RS02060	COG0004	ammonium transporteR
VITFI_RS02075	COG0800	Aldolase
VITFI_RS02105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
VITFI_RS02110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VITFI_RS02120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VITFI_RS02125	COG0604	alcohol dehydrogenase
VITFI_RS02135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VITFI_RS02160	COG1091	dTDP-4-dehydrorhamnose reductase activity
VITFI_RS02170	COG0513	Belongs to the DEAD box helicase family
VITFI_RS02180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VITFI_RS02185	COG0424	maF-like protein
VITFI_RS02190	COG1399	metal-binding, possibly nucleic acid-binding protein
VITFI_RS02195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VITFI_RS02200	COG0416	fatty acid biosynthetic process
VITFI_RS02205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VITFI_RS02210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VITFI_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS02220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VITFI_RS02225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VITFI_RS02245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_RS02250	COG0481	GTPase activity
VITFI_RS02265	COG0571	ribonuclease III activity
VITFI_RS02270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VITFI_RS02275	COG1381	Involved in DNA repair and RecF pathway recombination
VITFI_RS02280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VITFI_RS02285	COG0736	holo-[acyl-carrier-protein] synthase activity
VITFI_RS02305	COG1530	ribonuclease E activity
VITFI_RS02315	COG0564	pseudouridine synthase activity
VITFI_RS02330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VITFI_RS02330	COG0616	signal peptide processing
VITFI_RS02335	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VITFI_RS02340	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VITFI_RS02345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VITFI_RS02350	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
VITFI_RS02355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
VITFI_RS02360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
VITFI_RS02370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VITFI_RS02375	COG1333	cytochrome c biogenesis protein
VITFI_RS02385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VITFI_RS02395	COG0459	protein refolding
VITFI_RS02400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VITFI_RS02405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VITFI_RS02440	COG0110	maltose O-acetyltransferase activity
VITFI_RS02470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VITFI_RS02505	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VITFI_RS02510	COG4585	Histidine kinase
VITFI_RS02515	COG2197	response regulator
VITFI_RS02520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VITFI_RS02530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VITFI_RS02535	COG1181	Belongs to the D-alanine--D-alanine ligase family
VITFI_RS02540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VITFI_RS02545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VITFI_RS02550	COG0772	Belongs to the SEDS family
VITFI_RS02555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VITFI_RS02560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VITFI_RS02565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VITFI_RS02570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_RS02585	COG0275	rRNA processing
VITFI_RS02590	COG2814	Major facilitator Superfamily
VITFI_RS02605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VITFI_RS02610	COG1758	RNA polymerase activity
VITFI_RS02615	COG0194	GDP metabolic process
VITFI_RS02620	COG1561	YicC-like family, N-terminal region
VITFI_RS02630	COG0631	protein serine/threonine phosphatase activity
VITFI_RS02635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VITFI_RS02640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VITFI_RS02645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VITFI_RS02660	COG1193	negative regulation of DNA recombination
VITFI_RS02670	COG0307	riboflavin synthase, alpha
VITFI_RS02675	COG2003	Belongs to the UPF0758 family
VITFI_RS02680	COG2186	Transcriptional regulator
VITFI_RS02685	COG0573	inorganic phosphate transmembrane transporter activity
VITFI_RS02690	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_RS02700	COG3842	ATPase activity
VITFI_RS02710	COG1047	Peptidyl-prolyl cis-trans
VITFI_RS02715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VITFI_RS02720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VITFI_RS02725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VITFI_RS02735	COG0582	viral genome integration into host DNA
VITFI_RS02800	COG2204	response regulator
VITFI_RS02805	COG5000	phosphorelay sensor kinase activity
VITFI_RS02835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_RS02835	COG2022	thiamine diphosphate biosynthetic process
VITFI_RS02840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VITFI_RS02845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VITFI_RS02855	COG0551	DNA topoisomerase type I activity
VITFI_RS02855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VITFI_RS02890	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_RS02900	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
VITFI_RS02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_RS02970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VITFI_RS02980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VITFI_RS02990	COG2267	carboxylic ester hydrolase activity
VITFI_RS02995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_RS03005	COG4654	Cytochrome c, class I
VITFI_RS03010	COG0191	fructose-bisphosphate aldolase activity
VITFI_RS03015	COG0546	phosphoglycolate phosphatase activity
VITFI_RS03020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VITFI_RS03025	COG3954	Phosphoribulokinase
VITFI_RS03035	COG0464	growth
VITFI_RS03050	COG2369	cell adhesion
VITFI_RS03060	COG4373	Mu-like prophage FluMu protein gp28
VITFI_RS03210	COG2974	May be involved in recombination
VITFI_RS03285	COG4373	Mu-like prophage FluMu protein gp28
VITFI_RS03290	COG4383	Mu-like prophage protein gp29
VITFI_RS03320	COG4397	Mu-like prophage major head subunit gpT
VITFI_RS03395	COG3186	Phenylalanine-4-hydroxylase
VITFI_RS03405	COG0583	DNA-binding transcription factor activity
VITFI_RS03415	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VITFI_RS03420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VITFI_RS03445	COG1045	serine acetyltransferase
VITFI_RS03455	COG0297	glycogen (starch) synthase activity
VITFI_RS03455	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS03480	COG0489	protein tyrosine kinase activity
VITFI_RS03510	COG1216	Glycosyl transferase, family 2
VITFI_RS03510	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS03520	COG0792	nuclease activity
VITFI_RS03525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VITFI_RS03530	COG2823	Periplasmic or secreted lipoprotein
VITFI_RS03535	COG2084	Dehydrogenase
VITFI_RS03555	COG2233	PERMEase
VITFI_RS03575	COG0583	DNA-binding transcription factor activity
VITFI_RS03585	COG0861	Integral membrane protein TerC family
VITFI_RS03615	COG4239	(ABC) transporter, permease
VITFI_RS03620	COG0601	transmembrane transport
VITFI_RS03635	COG4166	transmembrane transport
VITFI_RS03675	COG0482	sulfurtransferase activity
VITFI_RS03690	COG4783	chaperone-mediated protein folding
VITFI_RS03695	COG0315	cyclic pyranopterin monophosphate synthase activity
VITFI_RS03700	COG3307	-O-antigen
VITFI_RS03725	COG1716	ATPase activity
VITFI_RS03730	COG0631	protein serine/threonine phosphatase activity
VITFI_RS03735	COG0861	Integral membrane protein TerC family
VITFI_RS03740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
VITFI_RS03745	COG0045	succinate-CoA ligase (ADP-forming) activity
VITFI_RS03755	COG2137	regulation of response to DNA damage stimulus
VITFI_RS03760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VITFI_RS03775	COG0772	Belongs to the SEDS family
VITFI_RS03780	COG0768	penicillin binding
VITFI_RS03795	COG1077	Cell shape determining protein MreB Mrl
VITFI_RS03800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VITFI_RS03805	COG0154	amidase activity
VITFI_RS03810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VITFI_RS03815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VITFI_RS03820	COG0708	Exodeoxyribonuclease III
VITFI_RS03825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VITFI_RS03845	COG2223	nitrite transmembrane transporter activity
VITFI_RS03860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VITFI_RS03875	COG2967	ApaG domain
VITFI_RS03885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VITFI_RS03890	COG0546	phosphoglycolate phosphatase activity
VITFI_RS03900	COG1196	nuclear chromosome segregation
VITFI_RS03910	COG0512	Glutamine amidotransferase of anthranilate synthase
VITFI_RS03920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VITFI_RS03925	COG0134	indole-3-glycerol-phosphate synthase activity
VITFI_RS03950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VITFI_RS03970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VITFI_RS03975	COG0081	regulation of translation
VITFI_RS03980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VITFI_RS03985	COG0222	ribosome binding
VITFI_RS03990	COG0085	RNA polymerase activity
VITFI_RS03995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VITFI_RS04000	COG0351	phosphomethylpyrimidine kinase
VITFI_RS04000	COG0352	thiamine-phosphate diphosphorylase activity
VITFI_RS04005	COG2022	thiamine diphosphate biosynthetic process
VITFI_RS04020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VITFI_RS04040	COG4999	Histidine kinase
VITFI_RS04040	COG3850	Histidine kinase
VITFI_RS04040	COG3437	response regulator, receiver
VITFI_RS04040	COG2205	protein histidine kinase activity
VITFI_RS04045	COG2258	MOSC domain
VITFI_RS04050	COG4636	protein conserved in cyanobacteria
VITFI_RS04055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VITFI_RS04065	COG1902	pentaerythritol trinitrate reductase activity
VITFI_RS04080	COG1696	Membrane protein involved in D-alanine export
VITFI_RS04085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VITFI_RS04105	COG2205	protein histidine kinase activity
VITFI_RS04105	COG0784	Response regulator, receiver
VITFI_RS04105	COG5002	protein histidine kinase activity
VITFI_RS04135	COG2203	Gaf domain
VITFI_RS04135	COG2199	diguanylate cyclase activity
VITFI_RS04140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VITFI_RS04150	COG1560	Kdo2-lipid A biosynthetic process
VITFI_RS04155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VITFI_RS04165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_RS04175	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
VITFI_RS04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_RS04215	COG0640	Transcriptional regulator
VITFI_RS04220	COG1937	Protein conserved in bacteria
VITFI_RS04245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VITFI_RS04250	COG1702	phosphate starvation-inducible protein PhoH
VITFI_RS04255	COG0632	four-way junction helicase activity
VITFI_RS04290	COG2255	four-way junction helicase activity
VITFI_RS04300	COG0840	transmembrane signaling receptor activity
VITFI_RS04305	COG0643	Histidine kinase
VITFI_RS04305	COG2198	Histidine kinase
VITFI_RS04330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_RS04335	COG2032	superoxide dismutase activity
VITFI_RS04360	COG0515	serine threonine protein kinase
VITFI_RS04360	COG2815	serine threonine protein kinase
VITFI_RS04420	COG0121	glutamine amidotransferase
VITFI_RS04440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VITFI_RS04450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VITFI_RS04455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_RS04490	COG4654	Cytochrome c, class I
VITFI_RS04495	COG0343	queuine tRNA-ribosyltransferase activity
VITFI_RS04500	COG1116	anion transmembrane transporter activity
VITFI_RS04500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_RS04515	COG0625	glutathione transferase activity
VITFI_RS04520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VITFI_RS04525	COG0284	orotidine-5'-phosphate decarboxylase activity
VITFI_RS04530	COG1280	lysine exporter protein (LysE YggA)
VITFI_RS04560	COG4628	conserved protein (DUF2132)
VITFI_RS04575	COG1569	PIN domain
VITFI_RS04580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_RS04595	COG1522	sequence-specific DNA binding
VITFI_RS04605	COG0633	Ferredoxin
VITFI_RS04605	COG0543	2 iron, 2 sulfur cluster binding
VITFI_RS04610	COG1151	hydroxylamine reductase activity
VITFI_RS04625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VITFI_RS04630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VITFI_RS04645	COG4452	Inner membrane protein CreD
VITFI_RS04650	COG2205	protein histidine kinase activity
VITFI_RS04655	COG2095	MarC family integral membrane protein
VITFI_RS04660	COG0724	RNA recognition motif
VITFI_RS04710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VITFI_RS04730	COG3344	reverse transcriptase
VITFI_RS04750	COG2843	Capsule synthesis protein
VITFI_RS04760	COG1760	l-serine dehydratase
VITFI_RS04765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_RS04770	COG0612	Peptidase, M16
VITFI_RS04785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
VITFI_RS04795	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VITFI_RS04805	COG0018	arginyl-trna synthetase
VITFI_RS04825	COG0583	DNA-binding transcription factor activity
VITFI_RS04835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VITFI_RS04845	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
VITFI_RS04860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VITFI_RS04865	COG1819	glycosyl
VITFI_RS04900	COG4654	Cytochrome c, class I
VITFI_RS04905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
VITFI_RS04955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VITFI_RS04960	COG0243	molybdopterin cofactor binding
VITFI_RS04970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VITFI_RS04975	COG0515	serine threonine protein kinase
VITFI_RS04975	COG2815	serine threonine protein kinase
VITFI_RS04980	COG2223	nitrite transmembrane transporter activity
VITFI_RS04990	COG0798	PFAM Bile acid sodium symporter
VITFI_RS04995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_RS05000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_RS05050	COG1230	cation diffusion facilitator family transporter
VITFI_RS05060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
VITFI_RS05075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VITFI_RS05080	COG0321	lipoyl(octanoyl) transferase activity
VITFI_RS05085	COG2921	Belongs to the UPF0250 family
VITFI_RS05095	COG1686	Belongs to the peptidase S11 family
VITFI_RS05105	COG3411	Ferredoxin
VITFI_RS05115	COG1981	membrane
VITFI_RS05125	COG0598	Magnesium transport protein CorA
VITFI_RS05145	COG2226	methyltransferase
VITFI_RS05150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_RS05160	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_RS05175	COG1858	cytochrome C peroxidase
VITFI_RS05180	COG0583	DNA-binding transcription factor activity
VITFI_RS05185	COG1850	ribulose-bisphosphate carboxylase activity
VITFI_RS05190	COG4451	ribulose bisphosphate carboxylase, small
VITFI_RS05265	COG4397	Mu-like prophage major head subunit gpT
VITFI_RS05300	COG4383	Mu-like prophage protein gp29
VITFI_RS05305	COG4373	Mu-like prophage FluMu protein gp28
VITFI_RS05380	COG2974	May be involved in recombination
VITFI_RS05445	COG1218	3'(2'),5'-bisphosphate nucleotidase
VITFI_RS05450	COG0175	sulfate reduction
VITFI_RS05460	COG0471	metal ion transport
VITFI_RS05460	COG3273	potassium ion transport
VITFI_RS05500	COG0356	it plays a direct role in the translocation of protons across the membrane
VITFI_RS05510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VITFI_RS05515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VITFI_RS05520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VITFI_RS05525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VITFI_RS05530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VITFI_RS05535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VITFI_RS05555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VITFI_RS05560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VITFI_RS05565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_RS05570	COG3162	membrane
VITFI_RS05575	COG0210	DNA helicase
VITFI_RS05585	COG3158	transport of potassium into the cell
VITFI_RS05595	COG0004	ammonium transporteR
VITFI_RS05610	COG3344	reverse transcriptase
VITFI_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VITFI_RS05680	COG2096	Adenosyltransferase
VITFI_RS05690	COG2201	protein-glutamate methylesterase activity
VITFI_RS05695	COG2198	Histidine kinase
VITFI_RS05695	COG0643	Histidine kinase
VITFI_RS05705	COG1116	anion transmembrane transporter activity
VITFI_RS05710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VITFI_RS05715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_RS05755	COG2030	dehydratase
VITFI_RS05760	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS05765	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_RS05770	COG0784	Response regulator, receiver
VITFI_RS05770	COG4191	Histidine kinase
VITFI_RS05775	COG0745	RESPONSE REGULATOR receiver
VITFI_RS05785	COG2852	Protein conserved in bacteria
VITFI_RS05790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_RS05835	COG0183	Belongs to the thiolase family
VITFI_RS05840	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS05845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_RS05860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_RS05860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_RS05860	COG1703	isobutyryl-CoA mutase activity
VITFI_RS05875	COG0583	DNA-binding transcription factor activity
VITFI_RS05885	COG3706	GGDEF domain
VITFI_RS05895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VITFI_RS05920	COG0330	HflC and HflK could
VITFI_RS05930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VITFI_RS05955	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
VITFI_RS05975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_RS05985	COG4566	intracellular signal transduction
VITFI_RS06010	COG0180	Tryptophanyl-tRNA synthetase
VITFI_RS06015	COG0697	spore germination
VITFI_RS06025	COG1216	Glycosyl transferase, family 2
VITFI_RS06055	COG0586	Pfam SNARE associated Golgi protein
VITFI_RS06060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VITFI_RS06065	COG0277	FAD linked oxidase domain protein
VITFI_RS06075	COG0312	modulator of DNA gyrase
VITFI_RS06080	COG1448	Aminotransferase
VITFI_RS06085	COG1858	cytochrome C peroxidase
VITFI_RS06105	COG0642	Histidine kinase
VITFI_RS06110	COG0583	DNA-binding transcription factor activity
VITFI_RS06125	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS06140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VITFI_RS06150	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_RS06155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VITFI_RS06160	COG0049	tRNA binding
VITFI_RS06165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VITFI_RS06170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VITFI_RS06175	COG0051	transcription antitermination factor activity, RNA binding
VITFI_RS06180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VITFI_RS06185	COG0088	Forms part of the polypeptide exit tunnel
VITFI_RS06190	COG0089	rRNA binding
VITFI_RS06195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VITFI_RS06200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VITFI_RS06205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VITFI_RS06210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VITFI_RS06215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VITFI_RS06220	COG0255	Belongs to the universal ribosomal protein uL29 family
VITFI_RS06225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VITFI_RS06230	COG0678	peroxiredoxin activity
VITFI_RS06235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VITFI_RS06240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VITFI_RS06245	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VITFI_RS06250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VITFI_RS06255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VITFI_RS06260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VITFI_RS06265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VITFI_RS06270	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VITFI_RS06275	COG1841	ribosomal large subunit assembly
VITFI_RS06280	COG0200	Binds to the 23S rRNA
VITFI_RS06285	COG0201	protein transport
VITFI_RS06295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VITFI_RS06300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VITFI_RS06305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VITFI_RS06310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VITFI_RS06315	COG0202	RNA polymerase activity
VITFI_RS06320	COG0203	ribosomal protein L17
VITFI_RS06325	COG4232	protein-disulfide reductase activity
VITFI_RS06335	COG1862	Preprotein translocase
VITFI_RS06340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VITFI_RS06345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VITFI_RS06355	COG2922	Belongs to the Smg family
VITFI_RS06360	COG0758	DNA mediated transformation
VITFI_RS06370	COG0242	peptide deformylase activity
VITFI_RS06375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VITFI_RS06380	COG0501	Belongs to the peptidase M48B family
VITFI_RS06395	COG0126	phosphoglycerate kinase activity
VITFI_RS06400	COG0280	phosphate acetyltransferase
VITFI_RS06400	COG0281	malic enzyme
VITFI_RS06405	COG0469	pyruvate kinase activity
VITFI_RS06420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VITFI_RS06435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VITFI_RS06440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VITFI_RS06445	COG0009	L-threonylcarbamoyladenylate synthase
VITFI_RS06460	COG2027	D-alanyl-D-alanine carboxypeptidase
VITFI_RS06465	COG1214	PFAM Peptidase M22, glycoprotease
VITFI_RS06470	COG0456	acetyltransferase
VITFI_RS06530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VITFI_RS06585	COG1278	Cold shock
VITFI_RS06595	COG0583	DNA-binding transcription factor activity
VITFI_RS06600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_RS06610	COG0679	Auxin Efflux Carrier
VITFI_RS06625	COG2176	DNA-directed DNA polymerase activity
VITFI_RS06645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VITFI_RS06670	COG4191	Histidine kinase
VITFI_RS06675	COG4566	intracellular signal transduction
VITFI_RS06680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VITFI_RS06685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VITFI_RS06690	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
VITFI_RS06695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VITFI_RS06700	COG3047	cAMP biosynthetic process
VITFI_RS06710	COG0583	DNA-binding transcription factor activity
VITFI_RS06750	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS06755	COG0726	polysaccharide deacetylase
VITFI_RS06755	COG1649	PFAM Uncharacterised BCR, COG1649
VITFI_RS06780	COG0037	tRNA processing
VITFI_RS06785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VITFI_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS06830	COG4569	acetaldehyde dehydrogenase (acetylating) activity
VITFI_RS06835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VITFI_RS06850	COG1802	Transcriptional regulator
VITFI_RS06915	COG0247	lactate metabolic process
VITFI_RS06920	COG0277	FAD linked oxidase domain protein
VITFI_RS06925	COG0277	FAD linked oxidase domain protein
VITFI_RS06960	COG0316	Belongs to the HesB IscA family
VITFI_RS06975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VITFI_RS06980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VITFI_RS07000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VITFI_RS07005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
VITFI_RS07010	COG4208	sulfate ABC transporter
VITFI_RS07015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VITFI_RS07020	COG1715	Restriction endonuclease
VITFI_RS07030	COG1196	nuclear chromosome segregation
VITFI_RS07035	COG0513	Belongs to the DEAD box helicase family
VITFI_RS07045	COG0583	DNA-binding transcription factor activity
VITFI_RS07065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VITFI_RS07070	COG0647	UMP catabolic process
VITFI_RS07080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VITFI_RS07090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
VITFI_RS07095	COG0735	belongs to the Fur family
VITFI_RS07100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VITFI_RS07105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VITFI_RS07125	COG0495	leucyl-tRNA aminoacylation
VITFI_RS07140	COG1058	Belongs to the CinA family
VITFI_RS07140	COG1546	Belongs to the CinA family
VITFI_RS07145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VITFI_RS07150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VITFI_RS07155	COG0513	Belongs to the DEAD box helicase family
VITFI_RS07170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VITFI_RS07205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VITFI_RS07210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_RS07215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VITFI_RS07225	COG0617	tRNA 3'-terminal CCA addition
VITFI_RS07235	COG0739	heme binding
VITFI_RS07235	COG0741	lytic transglycosylase activity
VITFI_RS07235	COG1196	nuclear chromosome segregation
VITFI_RS07245	COG0204	Acyl-transferase
VITFI_RS07250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VITFI_RS07255	COG0751	glycine-tRNA ligase activity
VITFI_RS07260	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_RS07265	COG0752	glycyl-tRNA synthetase alpha subunit
VITFI_RS07270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VITFI_RS07275	COG4535	Mg2 and Co2 transporter CorC
VITFI_RS07280	COG0523	cobalamin synthesis protein
VITFI_RS07295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VITFI_RS07300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VITFI_RS07325	COG1490	D-aminoacyl-tRNA deacylase activity
VITFI_RS07330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VITFI_RS07335	COG0545	Peptidyl-prolyl cis-trans isomerase
VITFI_RS07340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VITFI_RS07345	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VITFI_RS07355	COG0784	Response regulator, receiver
VITFI_RS07355	COG2205	protein histidine kinase activity
VITFI_RS07375	COG0326	Molecular chaperone. Has ATPase activity
VITFI_RS07395	COG0189	ligase activity
VITFI_RS07405	COG3259	Nickel-dependent hydrogenase
VITFI_RS07410	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
VITFI_RS07415	COG3383	formate dehydrogenase (NAD+) activity
VITFI_RS07420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
VITFI_RS07430	COG0488	(ABC) transporter
VITFI_RS07450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VITFI_RS07460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
VITFI_RS07475	COG1191	sigma factor activity
VITFI_RS07480	COG0183	Belongs to the thiolase family
VITFI_RS07530	COG2974	May be involved in recombination
VITFI_RS07605	COG4373	Mu-like prophage FluMu protein gp28
VITFI_RS07610	COG4383	Mu-like prophage protein gp29
VITFI_RS07640	COG4397	Mu-like prophage major head subunit gpT
VITFI_RS07745	COG3384	dioxygenase
VITFI_RS07750	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VITFI_RS07765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VITFI_RS07775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VITFI_RS07780	COG0196	riboflavin kinase activity
VITFI_RS07785	COG1187	pseudouridine synthase activity
VITFI_RS07795	COG0204	Acyl-transferase
VITFI_RS07795	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_RS07830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_RS07830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VITFI_RS07850	COG1139	Iron-sulfur cluster binding protein
VITFI_RS07860	COG0247	lactate metabolic process
VITFI_RS07865	COG2186	Transcriptional regulator
VITFI_RS07870	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
VITFI_RS07880	COG0668	transmembrane transport
VITFI_RS07885	COG1024	Enoyl-CoA hydratase
VITFI_RS07890	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_RS07895	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_RS07900	COG1024	Enoyl-CoA hydratase
VITFI_RS07935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VITFI_RS07985	COG0183	Belongs to the thiolase family
VITFI_RS07990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_RS07995	COG0183	Belongs to the thiolase family
VITFI_RS08015	COG1872	DUF167
VITFI_RS08045	COG2205	protein histidine kinase activity
VITFI_RS08060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VITFI_RS08065	COG2832	Protein of unknown function (DUF454)
VITFI_RS08075	COG1304	FMN binding
VITFI_RS08085	COG0583	DNA-binding transcription factor activity
VITFI_RS08095	COG1104	cysteine desulfurase activity
VITFI_RS08100	COG0822	iron-sulfur transferase activity
VITFI_RS08105	COG0316	Belongs to the HesB IscA family
VITFI_RS08115	COG0443	Heat shock 70 kDa protein
VITFI_RS08120	COG0633	Ferredoxin
VITFI_RS08155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
VITFI_RS08175	COG3411	Ferredoxin
VITFI_RS08185	COG2244	polysaccharide biosynthetic process
VITFI_RS08200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VITFI_RS08220	COG5554	nitrogen fixation
VITFI_RS08240	COG5554	nitrogen fixation
VITFI_RS08250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VITFI_RS08275	COG0617	tRNA 3'-terminal CCA addition
VITFI_RS08340	COG0210	DNA helicase
VITFI_RS08355	COG1722	exodeoxyribonuclease VII activity
VITFI_RS08365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VITFI_RS08370	COG1469	GTP cyclohydrolase I activity
VITFI_RS08375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VITFI_RS08410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VITFI_RS08415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VITFI_RS08420	COG0741	lytic transglycosylase activity
VITFI_RS08425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VITFI_RS08435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VITFI_RS08445	COG4771	TonB-dependent receptor
VITFI_RS08450	COG0259	pyridoxamine-phosphate oxidase activity
VITFI_RS08460	COG0746	molybdenum cofactor guanylyltransferase activity
VITFI_RS08465	COG0489	protein tyrosine kinase activity
VITFI_RS08485	COG0418	dihydroorotase activity
VITFI_RS08505	COG0564	pseudouridine synthase activity
VITFI_RS08510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
VITFI_RS08520	COG3025	triphosphatase activity
VITFI_RS08535	COG4232	protein-disulfide reductase activity
VITFI_RS08595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VITFI_RS08600	COG0793	Belongs to the peptidase S41A family
VITFI_RS08605	COG3842	ATPase activity
VITFI_RS08620	COG0659	secondary active sulfate transmembrane transporter activity
VITFI_RS08625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_RS08625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_RS08630	COG0830	nickel cation binding
VITFI_RS08635	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
VITFI_RS08640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VITFI_RS08645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VITFI_RS08670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VITFI_RS08685	COG1136	(ABC) transporter
VITFI_RS08700	COG1309	transcriptional regulator
VITFI_RS08710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
VITFI_RS08720	COG0804	urea catabolic process
VITFI_RS08725	COG0832	Belongs to the urease beta subunit family
VITFI_RS08730	COG0831	urea catabolic process
VITFI_RS08735	COG0366	Alpha amylase catalytic
VITFI_RS08740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VITFI_RS08750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VITFI_RS08755	COG0297	glycogen (starch) synthase activity
VITFI_RS08760	COG0058	SHG alpha-glucan phosphorylase activity
VITFI_RS08775	COG3275	phosphorelay sensor kinase activity
VITFI_RS08805	COG1136	(ABC) transporter
VITFI_RS08825	COG0433	COG0433 Predicted ATPase
VITFI_RS08830	COG0217	transcriptional regulatory protein
VITFI_RS08835	COG0151	Belongs to the GarS family
VITFI_RS08840	COG0408	coproporphyrinogen oxidase activity
VITFI_RS08845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VITFI_RS08850	COG0799	negative regulation of ribosome biogenesis
VITFI_RS08855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VITFI_RS08875	COG0424	maF-like protein
VITFI_RS08880	COG1530	ribonuclease E activity
VITFI_RS08885	COG0823	Involved in the tonB-independent uptake of proteins
VITFI_RS08900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VITFI_RS08920	COG1393	Belongs to the ArsC family
VITFI_RS08925	COG0248	Ppx GppA phosphatase
VITFI_RS08935	COG0745	RESPONSE REGULATOR receiver
VITFI_RS08940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VITFI_RS08945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VITFI_RS08955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VITFI_RS08960	COG0670	Belongs to the BI1 family
VITFI_RS08980	COG0505	Belongs to the CarA family
VITFI_RS08990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VITFI_RS08995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VITFI_RS09010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VITFI_RS09015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VITFI_RS09025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VITFI_RS09030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VITFI_RS09035	COG0573	inorganic phosphate transmembrane transporter activity
VITFI_RS09040	COG0581	inorganic phosphate transmembrane transporter activity
VITFI_RS09045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VITFI_RS09055	COG0745	RESPONSE REGULATOR receiver
VITFI_RS09070	COG0254	rRNA binding
VITFI_RS09075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VITFI_RS09090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VITFI_RS09095	COG0252	asparaginase activity
VITFI_RS09100	COG0488	(ABC) transporter
VITFI_RS09105	COG2890	protein-(glutamine-N5) methyltransferase activity
VITFI_RS09110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VITFI_RS09120	COG2171	N-acyltransferase activity
VITFI_RS09130	COG0436	Aminotransferase
VITFI_RS09140	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
VITFI_RS09150	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
VITFI_RS09160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
VITFI_RS09165	COG0298	carbon dioxide binding
VITFI_RS09170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_RS09175	COG1773	rubredoxin
VITFI_RS09180	COG1773	rubredoxin
VITFI_RS09185	COG1773	rubredoxin
VITFI_RS09190	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
VITFI_RS09195	COG0375	protein maturation
VITFI_RS09200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
VITFI_RS09205	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
VITFI_RS09210	COG0298	carbon dioxide binding
VITFI_RS09215	COG0409	Hydrogenase expression formation protein
VITFI_RS09220	COG0309	Hydrogenase expression formation protein (HypE)
VITFI_RS09235	COG3852	Histidine kinase
VITFI_RS09245	COG0174	glutamine synthetase
VITFI_RS09285	COG0563	adenylate kinase activity
VITFI_RS09290	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VITFI_RS09295	COG2835	tetraacyldisaccharide 4'-kinase activity
VITFI_RS09295	COG1663	tetraacyldisaccharide 4'-kinase activity
VITFI_RS09300	COG1663	tetraacyldisaccharide 4'-kinase activity
VITFI_RS09305	COG0848	biopolymer transport protein
VITFI_RS09310	COG0811	peptide transport
VITFI_RS09315	COG1570	exodeoxyribonuclease VII activity
VITFI_RS09320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
VITFI_RS09330	COG2205	protein histidine kinase activity
VITFI_RS09350	COG0084	hydrolase, TatD family'
VITFI_RS09355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
VITFI_RS09360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VITFI_RS09370	COG2217	Heavy metal translocating P-type atpase
VITFI_RS09380	COG3278	Belongs to the heme-copper respiratory oxidase family
VITFI_RS09410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_RS09415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VITFI_RS09430	COG1278	Cold shock
VITFI_RS09435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VITFI_RS09440	COG0542	response to heat
VITFI_RS09445	COG0300	oxidoreductase activity
VITFI_RS09465	COG0837	glucose binding
VITFI_RS09470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VITFI_RS09475	COG0779	Required for maturation of 30S ribosomal subunits
VITFI_RS09480	COG2251	uridine kinase activity
VITFI_RS09480	COG0195	Participates in both transcription termination and antitermination
VITFI_RS09485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VITFI_RS09490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VITFI_RS09495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VITFI_RS09500	COG1217	gtp-binding protein TYPA
VITFI_RS09510	COG0697	spore germination
VITFI_RS09530	COG0513	Belongs to the DEAD box helicase family
VITFI_RS09555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VITFI_RS09570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VITFI_RS09575	COG2878	Part of a membrane complex involved in electron transport
VITFI_RS09590	COG0556	nucleotide-excision repair
VITFI_RS09595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_RS09600	COG1959	2 iron, 2 sulfur cluster binding
VITFI_RS09605	COG1104	cysteine desulfurase activity
VITFI_RS09610	COG0822	iron-sulfur transferase activity
VITFI_RS09615	COG0316	Belongs to the HesB IscA family
VITFI_RS09625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VITFI_RS09630	COG0443	Heat shock 70 kDa protein
VITFI_RS09635	COG0633	Ferredoxin
VITFI_RS09640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VITFI_RS09650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VITFI_RS09655	COG1185	polyribonucleotide nucleotidyltransferase activity
VITFI_RS09660	COG0604	alcohol dehydrogenase
VITFI_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS09660	COG3321	synthase
VITFI_RS09665	COG0149	triose-phosphate isomerase activity
VITFI_RS09680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_RS09685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_RS09690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_RS09695	COG0649	NAD binding
VITFI_RS09700	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
VITFI_RS09710	COG1034	ATP synthesis coupled electron transport
VITFI_RS09715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
VITFI_RS09720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_RS09730	COG0713	ATP synthesis coupled electron transport
VITFI_RS09745	COG1007	ATP synthesis coupled electron transport
VITFI_RS09755	COG0494	nUDIX hydrolase
VITFI_RS09765	COG0277	FAD linked oxidase domain protein
VITFI_RS09775	COG1295	ribonuclease BN
VITFI_RS09780	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
VITFI_RS09785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VITFI_RS09790	COG3781	membrane
VITFI_RS09795	COG0626	cystathionine gamma-synthase activity
VITFI_RS09800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VITFI_RS09810	COG2914	Belongs to the UPF0125 (RnfH) family
VITFI_RS09835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VITFI_RS09835	COG0519	Catalyzes the synthesis of GMP from XMP
VITFI_RS09855	COG2351	hydroxyisourate hydrolase activity
VITFI_RS09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VITFI_RS09880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_RS09885	COG1116	anion transmembrane transporter activity
VITFI_RS09890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VITFI_RS09905	COG1619	proteins homologs of microcin C7 resistance protein MccF
VITFI_RS09915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VITFI_RS09955	COG3220	belongs to the UPF0276 family
VITFI_RS09965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VITFI_RS09975	COG0848	biopolymer transport protein
VITFI_RS09980	COG0811	peptide transport
VITFI_RS09985	COG0824	Thioesterase
VITFI_RS09990	COG0515	serine threonine protein kinase
VITFI_RS09990	COG2815	serine threonine protein kinase
VITFI_RS09995	COG0436	Aminotransferase
VITFI_RS10000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VITFI_RS10005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VITFI_RS10015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VITFI_RS10015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VITFI_RS10025	COG0583	DNA-binding transcription factor activity
VITFI_RS10030	COG0456	acetyltransferase
VITFI_RS10050	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS10075	COG1131	(ABC) transporter
VITFI_RS10160	COG3243	poly(R)-hydroxyalkanoic acid synthase
VITFI_RS10165	COG0183	Belongs to the thiolase family
VITFI_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS10180	COG1192	Involved in chromosome partitioning
VITFI_RS10185	COG2026	Addiction module toxin, RelE StbE family
VITFI_RS10220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VITFI_RS10235	COG3437	response regulator, receiver
VITFI_RS10245	COG0395	ABC-type sugar transport system, permease component
VITFI_RS10305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VITFI_RS10310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VITFI_RS10315	COG0443	Heat shock 70 kDa protein
VITFI_RS10320	COG0484	heat shock protein binding
VITFI_RS10330	COG0359	binds to the 23S rRNA
VITFI_RS10335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VITFI_RS10345	COG0360	Binds together with S18 to 16S ribosomal RNA
VITFI_RS10355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VITFI_RS10380	COG3622	Belongs to the hyi family
VITFI_RS10385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VITFI_RS10395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VITFI_RS10395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VITFI_RS10400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VITFI_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS10425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VITFI_RS10435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VITFI_RS10440	COG0513	Belongs to the DEAD box helicase family
VITFI_RS10445	COG0488	(ABC) transporter
VITFI_RS10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_RS10535	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
VITFI_RS10635	COG0737	Belongs to the 5'-nucleotidase family
VITFI_RS10645	COG1518	maintenance of DNA repeat elements
VITFI_RS10655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VITFI_RS10660	COG1074	ATP-dependent DNA helicase activity
VITFI_RS10665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VITFI_RS10670	COG0400	carboxylic ester hydrolase activity
VITFI_RS10675	COG3022	response to hydroperoxide
VITFI_RS10700	COG1309	transcriptional regulator
VITFI_RS10715	COG1136	(ABC) transporter
VITFI_RS10730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VITFI_RS10755	COG0586	Pfam SNARE associated Golgi protein
VITFI_RS10760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VITFI_RS10765	COG1187	pseudouridine synthase activity
VITFI_RS10770	COG2814	Major facilitator Superfamily
VITFI_RS10775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VITFI_RS10790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VITFI_RS10810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VITFI_RS10815	COG3228	Belongs to the MtfA family
VITFI_RS10820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_RS10835	COG0215	cysteine-tRNA ligase activity
VITFI_RS10845	COG0825	malonyl-CoA metabolic process
VITFI_RS10850	COG0037	tRNA processing
VITFI_RS10855	COG0527	aspartate kinase activity
VITFI_RS10865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_RS10915	COG1177	transmembrane transport
VITFI_RS10920	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_RS10925	COG3842	ATPase activity
VITFI_RS10930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VITFI_RS10945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
VITFI_RS10950	COG1522	sequence-specific DNA binding
VITFI_RS10960	COG0010	Belongs to the arginase family
VITFI_RS10965	COG2224	Isocitrate lyase
VITFI_RS10980	COG0560	Phosphoserine phosphatase
VITFI_RS11000	COG0826	peptidase U32
VITFI_RS11005	COG0084	hydrolase, TatD family'
VITFI_RS11020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VITFI_RS11025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VITFI_RS11040	COG0657	acetylesterase activity
VITFI_RS11045	COG0004	ammonium transporteR
VITFI_RS11060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
VITFI_RS11090	COG0174	glutamine synthetase
VITFI_RS11095	COG0613	PHP domain protein
VITFI_RS11100	COG0009	L-threonylcarbamoyladenylate synthase
VITFI_RS11110	COG0251	oxidation-reduction process
VITFI_RS11115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VITFI_RS11125	COG0667	Aldo Keto reductase
VITFI_RS11130	COG1024	Enoyl-CoA hydratase
VITFI_RS11135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VITFI_RS11140	COG0509	glycine decarboxylation via glycine cleavage system
VITFI_RS11145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VITFI_RS11145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VITFI_RS11160	COG3344	reverse transcriptase
VITFI_RS11180	COG3344	reverse transcriptase
VITFI_RS11190	COG3344	reverse transcriptase
VITFI_RS11225	COG2146	nitrite reductase [NAD(P)H] activity
VITFI_RS11230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VITFI_RS11235	COG0560	Phosphoserine phosphatase
VITFI_RS11240	COG0517	IMP dehydrogenase activity
VITFI_RS11240	COG0516	GMP reductase activity
VITFI_RS11255	COG1643	Atp-dependent helicase
VITFI_RS11265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VITFI_RS11265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VITFI_RS11270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VITFI_RS11275	COG1840	ABC-type Fe3 transport system, periplasmic component
VITFI_RS11290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_RS11295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
VITFI_RS11305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VITFI_RS11310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VITFI_RS11315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VITFI_RS11320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_RS11325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_RS11330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VITFI_RS11335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_RS11350	COG0750	zinc metalloprotease
VITFI_RS11355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VITFI_RS11360	COG0575	Belongs to the CDS family
VITFI_RS11370	COG0233	cytoplasmic translational termination
VITFI_RS11375	COG0528	UMP kinase activity
VITFI_RS11380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VITFI_RS11385	COG0052	Belongs to the universal ribosomal protein uS2 family
VITFI_RS11390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VITFI_RS11390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VITFI_RS11395	COG1666	GTP binding
VITFI_RS11400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VITFI_RS11425	COG0242	peptide deformylase activity
VITFI_RS11435	COG4181	ATPase activity
VITFI_RS11440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_RS11450	COG2917	probably involved in intracellular septation
VITFI_RS11455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VITFI_RS11465	COG0559	Belongs to the binding-protein-dependent transport system permease family
VITFI_RS11475	COG0411	ABC transporter
VITFI_RS11510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_RS11520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_RS11545	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VITFI_RS11550	COG1196	nuclear chromosome segregation
VITFI_RS11565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VITFI_RS11580	COG0860	N-Acetylmuramoyl-L-alanine amidase
VITFI_RS11585	COG0802	atpase or kinase
VITFI_RS11590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VITFI_RS11605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VITFI_RS11610	COG0765	amino acid transport
VITFI_RS11620	COG2833	Protein of unknown function (DUF455)
VITFI_RS11625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VITFI_RS11650	COG0148	phosphopyruvate hydratase activity
VITFI_RS11655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VITFI_RS11660	COG0504	CTP synthase activity
VITFI_RS11670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VITFI_RS11675	COG0483	inositol monophosphate 1-phosphatase activity
VITFI_RS11680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VITFI_RS11685	COG1045	serine acetyltransferase
VITFI_RS11700	COG4181	ATPase activity
VITFI_RS11705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VITFI_RS11720	COG0589	response to stress
VITFI_RS11740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_RS11755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VITFI_RS11760	COG0322	excinuclease ABC activity
VITFI_RS11790	COG1518	maintenance of DNA repeat elements
VITFI_RS11795	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
VITFI_RS11805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VITFI_RS11810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_RS11810	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VITFI_RS11815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VITFI_RS11820	COG0167	dihydroorotate dehydrogenase activity
VITFI_RS11840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
VITFI_RS11845	COG3706	GGDEF domain
VITFI_RS11850	COG2204	response regulator
VITFI_RS11860	COG2183	response to ionizing radiation
VITFI_RS11885	COG4335	DNA alkylation repair
VITFI_RS11900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VITFI_RS11905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VITFI_RS11910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VITFI_RS11925	COG0438	transferase activity, transferring glycosyl groups
VITFI_RS11935	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VITFI_RS11945	COG0776	regulation of translation
VITFI_RS11955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VITFI_RS11960	COG0287	Prephenate dehydrogenase
VITFI_RS11965	COG0077	Prephenate dehydratase
VITFI_RS11965	COG1605	Chorismate mutase
VITFI_RS11970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VITFI_RS11990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VITFI_RS12010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VITFI_RS12035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VITFI_RS12055	COG0123	including yeast histone deacetylase and acetoin utilization protein
VITFI_RS12075	COG0339	signal peptide processing
VITFI_RS12080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VITFI_RS12085	COG4566	intracellular signal transduction
VITFI_RS12090	COG4191	Histidine kinase
VITFI_RS12100	COG0508	dehydrogenase complex catalyzes the overall conversion of
VITFI_RS12105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VITFI_RS12110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VITFI_RS12110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VITFI_RS12125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VITFI_RS12130	COG0492	ferredoxin-NADP+ reductase activity
VITFI_RS12135	COG1674	ftsk spoiiie
VITFI_RS12140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VITFI_RS12145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VITFI_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS12175	COG3132	Protein of unknown function, DUF480
VITFI_RS12200	COG4774	siderophore transport
VITFI_RS12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VITFI_RS12210	COG1648	precorrin-2 dehydrogenase activity
VITFI_RS12210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VITFI_RS12215	COG0175	sulfate reduction
VITFI_RS12230	COG1136	(ABC) transporter
VITFI_RS12235	COG4591	ABC-type transport system involved in lipoprotein release permease component
VITFI_RS12255	COG4969	Belongs to the N-Me-Phe pilin family
VITFI_RS12290	COG0829	nickel cation binding
VITFI_RS12310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VITFI_RS12310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VITFI_RS12325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VITFI_RS12350	COG0028	Belongs to the TPP enzyme family
VITFI_RS12355	COG0440	acetolactate synthase activity
VITFI_RS12360	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VITFI_RS12365	COG1183	phosphatidylcholine synthase activity
VITFI_RS12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VITFI_RS12380	COG1414	Transcriptional regulator
VITFI_RS12385	COG0493	'glutamate synthase
VITFI_RS12385	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
VITFI_RS12395	COG1562	ergosterol biosynthetic process
VITFI_RS12415	COG0544	peptidyl-prolyl cis-trans isomerase activity
VITFI_RS12420	COG0740	serine-type endopeptidase activity
VITFI_RS12425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VITFI_RS12430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VITFI_RS12460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VITFI_RS12465	COG1125	glycine betaine transport
VITFI_RS12465	COG0517	IMP dehydrogenase activity
VITFI_RS12470	COG0047	phosphoribosylformylglycinamidine synthase activity
VITFI_RS12470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VITFI_RS12485	COG0745	RESPONSE REGULATOR receiver
VITFI_RS12490	COG0642	Histidine kinase
VITFI_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS12535	COG1132	(ABC) transporter
VITFI_RS12540	COG1132	(ABC) transporter
VITFI_RS12545	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VITFI_RS12555	COG1162	GTPase activity
VITFI_RS12575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
VITFI_RS12580	COG0494	nUDIX hydrolase
VITFI_RS12585	COG0335	large ribosomal subunit rRNA binding
VITFI_RS12590	COG0336	Belongs to the RNA methyltransferase TrmD family
VITFI_RS12595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VITFI_RS12600	COG0228	four-way junction DNA binding
VITFI_RS12615	COG0306	phosphate transporter
VITFI_RS12620	COG1392	Phosphate transport regulator
VITFI_RS12630	COG0617	tRNA 3'-terminal CCA addition
VITFI_RS12645	COG0628	permease
VITFI_RS12650	COG0728	peptidoglycan biosynthetic process
VITFI_RS12655	COG0268	Binds directly to 16S ribosomal RNA
VITFI_RS12670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VITFI_RS12690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VITFI_RS12715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_RS12720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VITFI_RS12725	COG0129	dihydroxy-acid dehydratase activity
VITFI_RS12735	COG4654	Cytochrome c, class I
VITFI_RS12755	COG3264	Mechanosensitive ion channel
VITFI_RS12755	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VITFI_RS12760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_RS12795	COG0714	Associated with various cellular activities
VITFI_RS12810	COG2951	lytic endotransglycosylase activity
VITFI_RS12825	COG0730	response to heat
VITFI_RS12830	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_RS12835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VITFI_RS12855	COG0583	DNA-binding transcription factor activity
VITFI_RS12860	COG0583	DNA-binding transcription factor activity
VITFI_RS12865	COG1902	pentaerythritol trinitrate reductase activity
VITFI_RS12870	COG0697	spore germination
VITFI_RS12890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_RS12915	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VITFI_RS12920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VITFI_RS12925	COG0312	modulator of DNA gyrase
VITFI_RS12930	COG3028	Belongs to the UPF0307 family
VITFI_RS12935	COG0521	Mo-molybdopterin cofactor biosynthetic process
VITFI_RS12990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VITFI_RS12995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VITFI_RS13005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VITFI_RS13010	COG0542	response to heat
VITFI_RS13015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VITFI_RS13020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VITFI_RS13025	COG0314	molybdopterin synthase activity
VITFI_RS13030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VITFI_RS13035	COG0303	'Molybdopterin
VITFI_RS13040	COG1763	Mo-molybdopterin cofactor biosynthetic process
VITFI_RS13070	COG0436	Aminotransferase
VITFI_RS13080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VITFI_RS13085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VITFI_RS13090	COG0791	NLP P60 protein
VITFI_RS13095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VITFI_RS13100	COG0328	RNA-DNA hybrid ribonuclease activity
VITFI_RS13110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VITFI_RS13115	COG0741	lytic transglycosylase activity
VITFI_RS13115	COG1388	LysM domain
VITFI_RS13120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VITFI_RS13125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VITFI_RS13130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VITFI_RS13135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VITFI_RS13150	COG2267	carboxylic ester hydrolase activity
VITFI_RS13155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_RS13175	COG0308	aminopeptidase N
VITFI_RS13180	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VITFI_RS13200	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS13210	COG0564	pseudouridine synthase activity
VITFI_RS13225	COG1136	(ABC) transporter
VITFI_RS13225	COG0577	efflux transmembrane transporter activity
VITFI_RS13230	COG0577	efflux transmembrane transporter activity
VITFI_RS13230	COG1136	(ABC) transporter
VITFI_RS13245	COG0579	oxidoreductase
VITFI_RS13265	COG1086	Polysaccharide biosynthesis protein
VITFI_RS13275	COG1741	Belongs to the pirin family
VITFI_RS13280	COG0583	DNA-binding transcription factor activity
VITFI_RS13285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_RS13290	COG1194	a g-specific adenine glycosylase
VITFI_RS13295	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
VITFI_RS13300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VITFI_RS13305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VITFI_RS13310	COG0724	RNA recognition motif
VITFI_RS13320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VITFI_RS13325	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VITFI_RS13335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VITFI_RS13340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VITFI_RS13355	COG0193	aminoacyl-tRNA hydrolase activity
VITFI_RS13365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VITFI_RS13370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VITFI_RS13375	COG0742	ribosomal rna small subunit methyltransferase
VITFI_RS13380	COG0107	imidazoleglycerol-phosphate synthase activity
VITFI_RS13385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VITFI_RS13395	COG0131	Imidazoleglycerol-phosphate dehydratase
VITFI_RS13400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VITFI_RS13455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VITFI_RS13460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VITFI_RS13465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VITFI_RS13475	COG0842	Transport permease protein
VITFI_RS13480	COG1131	(ABC) transporter
VITFI_RS13500	COG3119	arylsulfatase activity
VITFI_RS13515	COG0557	exoribonuclease II activity
VITFI_RS13525	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VITFI_RS13530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VITFI_RS13535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
VITFI_RS13545	COG0330	HflC and HflK could
VITFI_RS13550	COG0330	HflC and HflK could
VITFI_RS13555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VITFI_RS13560	COG1923	regulation of RNA biosynthetic process
VITFI_RS13565	COG1160	GTP binding
VITFI_RS13580	COG0124	histidyl-tRNA synthetase
VITFI_RS13585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VITFI_RS13600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VITFI_RS13605	COG0105	UTP biosynthetic process
VITFI_RS13610	COG1187	pseudouridine synthase activity
VITFI_RS13615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
VITFI_RS13620	COG0564	pseudouridine synthase activity
VITFI_RS13630	COG1199	ATP-dependent helicase activity
VITFI_RS13640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VITFI_RS13645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VITFI_RS13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
VITFI_RS13655	COG0567	Dehydrogenase, E1 component
VITFI_RS13670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VITFI_RS13675	COG0795	lipopolysaccharide-transporting ATPase activity
VITFI_RS13690	COG0583	DNA-binding transcription factor activity
VITFI_RS13695	COG0436	Aminotransferase
VITFI_RS13715	COG0528	UMP kinase activity
VITFI_RS13720	COG0528	UMP kinase activity
VITFI_RS13730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VITFI_RS13735	COG0725	ABC transporter, periplasmic molybdate-binding protein
VITFI_RS13740	COG4149	molybdate abc transporter
VITFI_RS13750	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
VITFI_RS13755	COG5420	small protein containing a coiled-coil domain
VITFI_RS13770	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_RS13780	COG0612	Peptidase, M16
VITFI_RS13805	COG5002	protein histidine kinase activity
VITFI_RS13820	COG1366	Belongs to the anti-sigma-factor antagonist family
VITFI_RS13830	COG1215	transferase activity, transferring glycosyl groups
VITFI_RS13840	COG0745	RESPONSE REGULATOR receiver
VITFI_RS13850	COG2197	response regulator
VITFI_RS13870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
VITFI_RS13885	COG0535	radical SAM domain protein
VITFI_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS13895	COG3706	GGDEF domain
VITFI_RS13900	COG0288	reversible hydration of carbon dioxide
VITFI_RS13910	COG0602	queuosine metabolic process
VITFI_RS13925	COG1420	regulation of RNA biosynthetic process
VITFI_RS13930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VITFI_RS13935	COG0497	DNA recombination
VITFI_RS13940	COG1660	Displays ATPase and GTPase activities
VITFI_RS13950	COG3706	GGDEF domain
VITFI_RS13950	COG4251	negative regulation of phosphorylation
VITFI_RS13950	COG2203	Gaf domain
VITFI_RS13950	COG5001	Diguanylate cyclase
VITFI_RS13955	COG0784	Response regulator, receiver
VITFI_RS13955	COG2205	protein histidine kinase activity
VITFI_RS13955	COG5002	protein histidine kinase activity
VITFI_RS13960	COG0583	DNA-binding transcription factor activity
VITFI_RS13965	COG5265	(ABC) transporter
VITFI_RS14030	COG4636	protein conserved in cyanobacteria
VITFI_RS14035	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS14040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VITFI_RS14070	COG4566	intracellular signal transduction
VITFI_RS14125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VITFI_RS14130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_RS14140	COG4804	nuclease activity
VITFI_RS14145	COG0732	type I restriction modification DNA specificity domain
VITFI_RS14150	COG2852	Protein conserved in bacteria
VITFI_RS14155	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
VITFI_RS14175	COG0673	inositol 2-dehydrogenase activity
VITFI_RS14195	COG0183	Belongs to the thiolase family
VITFI_RS14200	COG1024	Enoyl-CoA hydratase
VITFI_RS14200	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_RS14205	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS14230	COG2159	amidohydrolase
VITFI_RS14235	COG4115	mRNA cleavage
VITFI_RS14240	COG2161	toxin-antitoxin pair type II binding
VITFI_RS14255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VITFI_RS14260	COG0138	bifunctional purine biosynthesis protein purh
VITFI_RS14265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VITFI_RS14270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VITFI_RS14275	COG1238	metal cluster binding
VITFI_RS14280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VITFI_RS14285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VITFI_RS14290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
VITFI_RS14295	COG1765	OsmC-like protein
VITFI_RS14300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
VITFI_RS14315	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_RS14340	COG0653	protein targeting
VITFI_RS14350	COG0756	dUTP diphosphatase activity
VITFI_RS14355	COG4636	protein conserved in cyanobacteria
VITFI_RS14365	COG2850	peptidyl-arginine hydroxylation
VITFI_RS14375	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VITFI_RS14380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VITFI_RS14420	COG0745	RESPONSE REGULATOR receiver
VITFI_RS14450	COG0305	Participates in initiation and elongation during chromosome replication
VITFI_RS14475	COG0582	viral genome integration into host DNA
VITFI_RS14485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VITFI_RS14490	COG1968	undecaprenyl-diphosphatase activity
VITFI_RS14500	COG1309	transcriptional regulator
VITFI_RS14515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VITFI_RS14525	COG1538	Outer membrane efflux protein
VITFI_RS14590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_RS14595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VITFI_RS14605	COG0285	dihydrofolate synthase activity
VITFI_RS14610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VITFI_RS14615	COG0159	tryptophan synthase activity
VITFI_RS14620	COG0133	tryptophan synthase activity
VITFI_RS14625	COG0135	phosphoribosylanthranilate isomerase activity
VITFI_RS14630	COG0101	tRNA pseudouridine synthase activity
VITFI_RS14640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VITFI_RS14645	COG0473	3-isopropylmalate dehydrogenase activity
VITFI_RS14650	COG0066	3-isopropylmalate dehydratase activity
VITFI_RS14655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VITFI_RS14680	COG2124	cytochrome p450
VITFI_RS14685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VITFI_RS14690	COG0156	8-amino-7-oxononanoate synthase activity
VITFI_RS14705	COG4770	biotin carboxylase activity
VITFI_RS14710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VITFI_RS14715	COG1703	isobutyryl-CoA mutase activity
VITFI_RS14725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_RS14725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_RS14730	COG1802	Transcriptional regulator
VITFI_RS14760	COG0372	Belongs to the citrate synthase family
VITFI_RS14765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VITFI_RS14770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VITFI_RS14775	COG1053	succinate dehydrogenase
VITFI_RS14790	COG2188	Transcriptional regulator
VITFI_RS14795	COG0039	L-malate dehydrogenase activity
VITFI_RS14805	COG1049	propionate catabolic process, 2-methylcitrate cycle
VITFI_RS14810	COG2852	Protein conserved in bacteria
VITFI_RS14820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_RS14825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_RS14825	COG0543	2 iron, 2 sulfur cluster binding
VITFI_RS14860	COG0425	Belongs to the sulfur carrier protein TusA family
VITFI_RS14865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
VITFI_RS14870	COG0525	valine-tRNA ligase activity
VITFI_RS14880	COG0714	Associated with various cellular activities
VITFI_RS14885	COG3385	transposase activity
VITFI_RS14910	COG1280	lysine exporter protein (LysE YggA)
VITFI_RS14915	COG0583	DNA-binding transcription factor activity
VITFI_RS14920	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS14925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_RS14935	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VITFI_RS14955	COG3279	Response regulator of the LytR AlgR family
VITFI_RS14960	COG0165	Argininosuccinate lyase
VITFI_RS14980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VITFI_RS14995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VITFI_RS15005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VITFI_RS15010	COG2226	methyltransferase
VITFI_RS15025	COG2990	Protein conserved in bacteria
VITFI_RS15065	COG2154	pterin-4-alpha-carbinolamine dehydratase
VITFI_RS15075	COG0494	nUDIX hydrolase
VITFI_RS15080	COG3568	Endonuclease Exonuclease Phosphatase
VITFI_RS15085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VITFI_RS15130	COG1132	(ABC) transporter
VITFI_RS15135	COG0189	ligase activity
VITFI_RS15135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_RS15140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_RS15140	COG0189	ligase activity
VITFI_RS15160	COG1215	transferase activity, transferring glycosyl groups
VITFI_RS15165	COG0463	Glycosyl transferase, family 2
VITFI_RS15195	COG0028	Belongs to the TPP enzyme family
VITFI_RS15215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VITFI_RS15235	COG3842	ATPase activity
VITFI_RS15245	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_RS15270	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_RS15275	COG1024	Enoyl-CoA hydratase
VITFI_RS15295	COG0540	Belongs to the ATCase OTCase family
VITFI_RS15300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
VITFI_RS15305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VITFI_RS15310	COG1678	Uncharacterized ACR, COG1678
VITFI_RS15315	COG0415	Belongs to the DNA photolyase family
VITFI_RS15320	COG0643	Histidine kinase
VITFI_RS15320	COG2198	Histidine kinase
VITFI_RS15325	COG0840	transmembrane signaling receptor activity
VITFI_RS15345	COG1773	rubredoxin
VITFI_RS15355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VITFI_RS15365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VITFI_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_RS15385	COG0557	exoribonuclease II activity
VITFI_RS15395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VITFI_RS15400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VITFI_RS15410	COG0511	ligase activity, forming carbon-carbon bonds
VITFI_RS15415	COG0439	Biotin carboxylase
VITFI_RS15420	COG2264	protein methyltransferase activity
VITFI_RS15430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VITFI_RS15445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VITFI_RS15445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VITFI_RS15465	COG4137	Cytochrome C assembly protein
VITFI_RS15470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VITFI_RS15485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VITFI_RS15495	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VITFI_RS15500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VITFI_RS15505	COG2890	protein-(glutamine-N5) methyltransferase activity
VITFI_RS15510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VITFI_RS15520	COG0741	lytic transglycosylase activity
VITFI_RS15525	COG0442	prolyl-tRNA aminoacylation
VITFI_RS15530	COG0494	nUDIX hydrolase
VITFI_RS15535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VITFI_RS15540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VITFI_RS15545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VITFI_RS15550	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VITFI_RS15555	COG0142	geranyltranstransferase activity
VITFI_RS15580	COG0237	dephospho-CoA kinase activity
VITFI_RS15585	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VITFI_RS15590	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VITFI_RS15600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VITFI_RS15605	COG0181	hydroxymethylbilane synthase activity
VITFI_RS15630	COG0183	Belongs to the thiolase family
VITFI_RS15645	COG1024	Enoyl-CoA hydratase
VITFI_RS15680	COG1960	acyl-CoA dehydrogenase activity
VITFI_RS15700	COG3344	reverse transcriptase
VITFI_RS15720	COG4676	Protein conserved in bacteria
VITFI_RS15730	COG2828	Protein conserved in bacteria
VITFI_RS15740	COG2733	membrane
VITFI_RS15745	COG3162	membrane
VITFI_RS15750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_RS15865	COG4773	Receptor
VITFI_RS15870	COG0735	belongs to the Fur family
VITFI_RS15895	COG3128	pkhd-type hydroxylase
VITFI_RS15930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_RS15960	COG0012	GTP binding
VITFI_RS16005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_RS16035	COG1819	glycosyl
VITFI_RS16105	COG0667	Aldo Keto reductase
VITFI_RS16140	COG2124	cytochrome p450
VITFI_RS16155	COG0784	Response regulator, receiver
VITFI_RS16155	COG5002	protein histidine kinase activity
VITFI_RS16155	COG2205	protein histidine kinase activity
VITFI_RS16170	COG2223	nitrite transmembrane transporter activity
VITFI_RS16260	COG2918	glutathione biosynthetic process
VITFI_RS16270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_RS16280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_RS16285	COG0765	amino acid transport
VITFI_RS16290	COG0765	amino acid transport
VITFI_RS16295	COG1126	abc transporter atp-binding protein
VITFI_RS16345	COG0277	FAD linked oxidase domain protein
VITFI_RS16355	COG1192	Involved in chromosome partitioning
VITFI_RS16370	COG1309	transcriptional regulator
VITFI_RS16380	COG1192	Involved in chromosome partitioning
VITFI_RS16385	COG1475	DNA binding
VITFI_RS16395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VITFI_RS16400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VITFI_RS16405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_RS16410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VITFI_RS16420	COG1082	Xylose isomerase domain protein TIM barrel
VITFI_RS16420	COG3185	4-Hydroxyphenylpyruvate dioxygenase
VITFI_RS16430	COG2070	2-Nitropropane dioxygenase
VITFI_RS16435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VITFI_RS16450	COG3384	dioxygenase
VITFI_RS16455	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_RS16485	COG1846	Transcriptional regulator
VITFI_RS16495	COG0033	Phosphoglucomutase
VITFI_RS16520	COG1797	cobyrinic acid a,c-diamide synthase activity
VITFI_RS16535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VITFI_RS16540	COG3411	Ferredoxin
VITFI_RS16550	COG0778	Nitroreductase
VITFI_RS16570	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
VITFI_RS16595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VITFI_RS16600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
VITFI_RS16610	COG0583	DNA-binding transcription factor activity
VITFI_RS16620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VITFI_RS16630	COG1120	ATPase activity
VITFI_RS16635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VITFI_RS16645	COG4206	TonB-dependent receptor
VITFI_RS16655	COG2204	response regulator
VITFI_RS16665	COG1858	cytochrome C peroxidase
VITFI_RS16670	COG1492	cobalamin metabolic process
VITFI_RS16685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VITFI_RS16700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_RS16705	COG0727	PFAM Uncharacterised protein family (UPF0153)
VITFI_RS16715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VITFI_RS16720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
VITFI_RS16740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_RS16745	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
VITFI_RS16765	COG3181	Tripartite tricarboxylate transporter family receptor
VITFI_RS16780	COG0420	3'-5' exonuclease activity
VITFI_RS16800	COG2843	Capsule synthesis protein
VITFI_RS16825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_RS16860	COG2337	Toxic component of a toxin-antitoxin (TA) module
VITFI_RS16865	COG0346	lactoylglutathione lyase activity
VITFI_RS16870	COG2119	membrane
VITFI_RS16880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_RS16935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_RS16945	COG0484	heat shock protein binding
VITFI_RS16955	COG2203	Gaf domain
VITFI_RS16955	COG2199	diguanylate cyclase activity
VITFI_RS16960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VITFI_RS16960	COG2755	lipolytic protein G-D-S-L family
VITFI_RS16975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VITFI_RS16980	COG0235	Class ii aldolase
VITFI_RS16985	COG3971	2-oxopent-4-enoate hydratase activity
VITFI_RS16995	COG0745	RESPONSE REGULATOR receiver
VITFI_RS17000	COG2205	protein histidine kinase activity
VITFI_RS17010	COG3550	peptidyl-serine autophosphorylation
VITFI_RS17030	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_RS17030	COG2030	dehydratase
VITFI_RS17040	COG0183	Belongs to the thiolase family
VITFI_RS17050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_RS17055	COG2151	metal-sulfur cluster biosynthetic enzyme
VITFI_RS17060	COG3396	Phenylacetate-CoA oxygenase
VITFI_RS17065	COG3460	Phenylacetate-CoA oxygenase
VITFI_RS17070	COG3396	Phenylacetate-CoA oxygenase
VITFI_RS17080	COG2050	protein possibly involved in aromatic compounds catabolism
VITFI_RS17085	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_RS17090	COG1024	Enoyl-CoA hydratase
VITFI_RS17105	COG1024	Enoyl-CoA hydratase
VITFI_RS17115	COG0583	DNA-binding transcription factor activity
VITFI_RS17135	COG4999	Histidine kinase
VITFI_RS17135	COG2205	protein histidine kinase activity
VITFI_RS17135	COG3437	response regulator, receiver
VITFI_RS17135	COG3850	Histidine kinase
VITFI_RS17155	COG0642	Histidine kinase
VITFI_RS17175	COG3706	GGDEF domain
VITFI_RS17210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VITFI_RS17225	COG0247	lactate metabolic process
VITFI_RS17230	COG0277	FAD linked oxidase domain protein
VITFI_RS17235	COG0277	FAD linked oxidase domain protein
VITFI_RS17245	COG2267	carboxylic ester hydrolase activity
VITFI_RS17270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_RS17275	COG1138	Cytochrome C-type biogenesis protein
VITFI_RS17280	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VITFI_RS17290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VITFI_RS17300	COG4133	protoheme IX ABC transporter activity
VITFI_RS17315	COG0243	molybdopterin cofactor binding
VITFI_RS17320	COG0437	4 iron, 4 sulfur cluster binding
VITFI_RS17325	COG0348	domain, Protein
VITFI_RS17385	COG0688	phosphatidylethanolamine metabolic process
VITFI_RS17395	COG2203	Gaf domain
VITFI_RS17395	COG2200	EAL domain
VITFI_RS17395	COG2199	diguanylate cyclase activity
VITFI_RS17420	COG2268	Band 7 protein
VITFI_RS17425	COG1585	Membrane protein implicated in regulation of membrane protease activity
VITFI_RS17440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_RS17455	COG3384	dioxygenase
VITFI_RS17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_RS17585	COG3077	Addiction module antitoxin, RelB DinJ family
VITFI_RS17590	COG3041	Addiction module toxin RelE StbE family
VITFI_RS17635	COG1309	transcriptional regulator
VITFI_RS17650	COG1136	(ABC) transporter
VITFI_RS17665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs