locus-tag	class	description
ADP71_RS00045	COG0477	Major facilitator Superfamily
ADP71_RS00085	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADP71_RS00090	COG3766	membrane
ADP71_RS00110	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ADP71_RS00170	COG0625	glutathione transferase activity
ADP71_RS00175	COG2969	positive regulation of protein catabolic process
ADP71_RS00205	COG1346	cytolysis
ADP71_RS00215	COG0616	signal peptide processing
ADP71_RS00215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADP71_RS00220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADP71_RS00225	COG0564	pseudouridine synthase activity
ADP71_RS00230	COG1530	ribonuclease E activity
ADP71_RS00270	COG1959	2 iron, 2 sulfur cluster binding
ADP71_RS00285	COG2095	MarC family integral membrane protein
ADP71_RS00300	COG0564	pseudouridine synthase activity
ADP71_RS00330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADP71_RS00335	COG0052	Belongs to the universal ribosomal protein uS2 family
ADP71_RS00340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADP71_RS00345	COG0528	UMP kinase activity
ADP71_RS00445	COG0589	response to stress
ADP71_RS00485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADP71_RS00500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ADP71_RS00515	COG1063	alcohol dehydrogenase
ADP71_RS00530	COG1960	acyl-CoA dehydrogenase activity
ADP71_RS00545	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADP71_RS00545	COG1024	Enoyl-CoA hydratase
ADP71_RS00550	COG0183	Belongs to the thiolase family
ADP71_RS00555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADP71_RS00620	COG1968	undecaprenyl-diphosphatase activity
ADP71_RS00655	COG0791	NLP P60 protein
ADP71_RS00675	COG0285	dihydrofolate synthase activity
ADP71_RS00715	COG0307	riboflavin synthase, alpha
ADP71_RS00720	COG1607	acyl-coa hydrolase
ADP71_RS00725	COG0598	Magnesium transport protein CorA
ADP71_RS00730	COG0248	Ppx GppA phosphatase
ADP71_RS00735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADP71_RS00755	COG2165	general secretion pathway protein
ADP71_RS00765	COG2239	Acts as a magnesium transporter
ADP71_RS00780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADP71_RS00785	COG2807	transmembrane transport
ADP71_RS00790	COG2207	Transcriptional regulator
ADP71_RS00795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADP71_RS00805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADP71_RS00825	COG1252	NADH dehydrogenase
ADP71_RS00845	COG0583	DNA-binding transcription factor activity
ADP71_RS00860	COG1305	Transglutaminase-like
ADP71_RS00870	COG2308	Evidence 4 Homologs of previously reported genes of
ADP71_RS00880	COG0583	DNA-binding transcription factor activity
ADP71_RS00885	COG1335	isochorismatase
ADP71_RS00895	COG1063	alcohol dehydrogenase
ADP71_RS00900	COG0402	S-adenosylhomocysteine deaminase activity
ADP71_RS00910	COG1757	Na H antiporter
ADP71_RS00935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADP71_RS00970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADP71_RS00990	COG0513	Belongs to the DEAD box helicase family
ADP71_RS01000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADP71_RS01065	COG0582	viral genome integration into host DNA
ADP71_RS01095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADP71_RS01110	COG1652	LysM domain
ADP71_RS01115	COG0268	Binds directly to 16S ribosomal RNA
ADP71_RS01130	COG0601	transmembrane transport
ADP71_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADP71_RS01140	COG0444	Belongs to the ABC transporter superfamily
ADP71_RS01145	COG4608	Belongs to the ABC transporter superfamily
ADP71_RS01150	COG1464	Belongs to the NlpA lipoprotein family
ADP71_RS01155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS01200	COG0640	Transcriptional regulator
ADP71_RS01210	COG1295	ribonuclease BN
ADP71_RS01215	COG0628	permease
ADP71_RS01255	COG1902	pentaerythritol trinitrate reductase activity
ADP71_RS01255	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADP71_RS01285	COG2304	oxidoreductase activity
ADP71_RS01320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADP71_RS01330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADP71_RS01335	COG0438	transferase activity, transferring glycosyl groups
ADP71_RS01400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADP71_RS01405	COG1088	dTDP-glucose 4,6-dehydratase activity
ADP71_RS01410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADP71_RS01410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADP71_RS01420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADP71_RS01430	COG0121	glutamine amidotransferase
ADP71_RS01445	COG2205	protein histidine kinase activity
ADP71_RS01450	COG0745	RESPONSE REGULATOR receiver
ADP71_RS01480	COG3411	Ferredoxin
ADP71_RS01500	COG0387	Pfam Sodium calcium exchanger
ADP71_RS01505	COG0590	tRNA wobble adenosine to inosine editing
ADP71_RS01520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADP71_RS01570	COG2814	Major facilitator Superfamily
ADP71_RS01575	COG0318	PFAM AMP-dependent synthetase and ligase
ADP71_RS01585	COG0756	dUTP diphosphatase activity
ADP71_RS01605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADP71_RS01615	COG1683	Conserved Protein
ADP71_RS01630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADP71_RS01650	COG1278	Cold shock
ADP71_RS01660	COG0542	response to heat
ADP71_RS01675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ADP71_RS01680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADP71_RS01680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADP71_RS01690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADP71_RS01695	COG2326	polyphosphate kinase activity
ADP71_RS01710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADP71_RS01720	COG0859	PFAM glycosyl transferase family 9
ADP71_RS01735	COG0196	riboflavin kinase activity
ADP71_RS01760	COG0488	(ABC) transporter
ADP71_RS01780	COG1199	ATP-dependent helicase activity
ADP71_RS01780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADP71_RS01840	COG0142	geranyltranstransferase activity
ADP71_RS01845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADP71_RS01870	COG0254	rRNA binding
ADP71_RS01880	COG0402	S-adenosylhomocysteine deaminase activity
ADP71_RS01890	COG2350	Protein conserved in bacteria
ADP71_RS01915	COG0501	Belongs to the peptidase M48B family
ADP71_RS01920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADP71_RS01925	COG0166	Belongs to the GPI family
ADP71_RS01940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADP71_RS01950	COG0135	phosphoribosylanthranilate isomerase activity
ADP71_RS01965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADP71_RS01975	COG2133	pyrroloquinoline quinone binding
ADP71_RS01980	COG5592	hemerythrin HHE cation binding domain
ADP71_RS02000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADP71_RS02020	COG1234	tRNA 3'-trailer cleavage
ADP71_RS02030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ADP71_RS02035	COG0351	phosphomethylpyrimidine kinase
ADP71_RS02050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADP71_RS02055	COG1183	phosphatidylcholine synthase activity
ADP71_RS02080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADP71_RS02085	COG2027	D-alanyl-D-alanine carboxypeptidase
ADP71_RS02105	COG2198	Histidine kinase
ADP71_RS02105	COG0643	Histidine kinase
ADP71_RS02115	COG0542	response to heat
ADP71_RS02125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADP71_RS02135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADP71_RS02140	COG1765	OsmC-like protein
ADP71_RS02165	COG0534	Mate efflux family protein
ADP71_RS02185	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADP71_RS02200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADP71_RS02210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADP71_RS02215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADP71_RS02255	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ADP71_RS02265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADP71_RS02280	COG1902	pentaerythritol trinitrate reductase activity
ADP71_RS02305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADP71_RS02345	COG0840	transmembrane signaling receptor activity
ADP71_RS02355	COG2975	iron-sulfur cluster assembly
ADP71_RS02360	COG0633	Ferredoxin
ADP71_RS02380	COG0822	iron-sulfur transferase activity
ADP71_RS02395	COG0560	Phosphoserine phosphatase
ADP71_RS02405	COG0386	Belongs to the glutathione peroxidase family
ADP71_RS02425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADP71_RS02440	COG2205	protein histidine kinase activity
ADP71_RS02440	COG0784	Response regulator, receiver
ADP71_RS02445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ADP71_RS02455	COG0247	lactate metabolic process
ADP71_RS02460	COG0277	FAD linked oxidase domain protein
ADP71_RS02465	COG0277	FAD linked oxidase domain protein
ADP71_RS02480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADP71_RS02540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ADP71_RS02545	COG0123	including yeast histone deacetylase and acetoin utilization protein
ADP71_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS02560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADP71_RS02575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADP71_RS02580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADP71_RS02590	COG4122	O-methyltransferase activity
ADP71_RS02600	COG0617	tRNA 3'-terminal CCA addition
ADP71_RS02605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADP71_RS02610	COG1428	Deoxynucleoside kinase
ADP71_RS02630	COG0012	GTP binding
ADP71_RS02665	COG0628	permease
ADP71_RS02670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADP71_RS02720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADP71_RS02760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADP71_RS02770	COG1047	Peptidyl-prolyl cis-trans
ADP71_RS02775	COG1522	sequence-specific DNA binding
ADP71_RS02790	COG1113	amino acid transport
ADP71_RS02840	COG1773	rubredoxin
ADP71_RS02845	COG1116	anion transmembrane transporter activity
ADP71_RS02850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADP71_RS02860	COG0252	asparaginase activity
ADP71_RS02875	COG0488	(ABC) transporter
ADP71_RS02885	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ADP71_RS02900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADP71_RS02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADP71_RS02970	COG0586	Pfam SNARE associated Golgi protein
ADP71_RS02975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADP71_RS02980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADP71_RS03015	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADP71_RS03055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADP71_RS03070	COG1309	transcriptional regulator
ADP71_RS03075	COG0433	COG0433 Predicted ATPase
ADP71_RS03095	COG0745	RESPONSE REGULATOR receiver
ADP71_RS03110	COG0352	thiamine-phosphate diphosphorylase activity
ADP71_RS03110	COG0351	phosphomethylpyrimidine kinase
ADP71_RS03110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ADP71_RS03120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ADP71_RS03165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADP71_RS03170	COG1393	Belongs to the ArsC family
ADP71_RS03190	COG0512	Glutamine amidotransferase of anthranilate synthase
ADP71_RS03210	COG1760	l-serine dehydratase
ADP71_RS03215	COG0741	lytic transglycosylase activity
ADP71_RS03215	COG1388	LysM domain
ADP71_RS03260	COG4208	sulfate ABC transporter
ADP71_RS03280	COG1012	belongs to the aldehyde dehydrogenase family
ADP71_RS03285	COG2233	PERMEase
ADP71_RS03295	COG1297	OPT oligopeptide transporter protein
ADP71_RS03300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADP71_RS03320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADP71_RS03330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ADP71_RS03335	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ADP71_RS03345	COG0497	DNA recombination
ADP71_RS03365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADP71_RS03370	COG3318	Belongs to the UPF0149 family
ADP71_RS03370	COG3012	SEC-C Motif Domain Protein
ADP71_RS03385	COG0772	Belongs to the SEDS family
ADP71_RS03390	COG0768	penicillin binding
ADP71_RS03400	COG1792	Involved in formation and maintenance of cell shape
ADP71_RS03405	COG1077	Cell shape determining protein MreB Mrl
ADP71_RS03410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADP71_RS03430	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ADP71_RS03445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADP71_RS03460	COG0129	dihydroxy-acid dehydratase activity
ADP71_RS03470	COG4783	chaperone-mediated protein folding
ADP71_RS03485	COG0537	adenosine 5'-monophosphoramidase activity
ADP71_RS03490	COG1304	FMN binding
ADP71_RS03495	COG1620	l-lactate permease
ADP71_RS03500	COG1139	Iron-sulfur cluster binding protein
ADP71_RS03510	COG0247	lactate metabolic process
ADP71_RS03515	COG2186	Transcriptional regulator
ADP71_RS03525	COG0513	Belongs to the DEAD box helicase family
ADP71_RS03530	COG1414	Transcriptional regulator
ADP71_RS03545	COG1074	ATP-dependent DNA helicase activity
ADP71_RS03550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ADP71_RS03600	COG1114	Component of the transport system for branched-chain amino acids
ADP71_RS03620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADP71_RS03630	COG2962	Rard protein
ADP71_RS03640	COG0330	HflC and HflK could
ADP71_RS03650	COG1464	Belongs to the NlpA lipoprotein family
ADP71_RS03655	COG2011	ABC-type metal ion transport system permease component
ADP71_RS03660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADP71_RS03665	COG3568	Endonuclease Exonuclease Phosphatase
ADP71_RS03670	COG0494	nUDIX hydrolase
ADP71_RS03675	COG1511	domain protein
ADP71_RS03675	COG3264	Mechanosensitive ion channel
ADP71_RS03690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADP71_RS03700	COG2951	lytic endotransglycosylase activity
ADP71_RS03705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADP71_RS03710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADP71_RS03720	COG3040	lipid binding
ADP71_RS03730	COG0251	oxidation-reduction process
ADP71_RS03750	COG1538	Outer membrane efflux protein
ADP71_RS03755	COG3012	SEC-C Motif Domain Protein
ADP71_RS03770	COG1115	amino acid carrier protein
ADP71_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS03785	COG1177	transmembrane transport
ADP71_RS03790	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADP71_RS03795	COG3842	ATPase activity
ADP71_RS03800	COG3135	benzoate transporter
ADP71_RS03820	COG2733	membrane
ADP71_RS03850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADP71_RS03855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADP71_RS03875	COG0488	(ABC) transporter
ADP71_RS03895	COG0010	Belongs to the arginase family
ADP71_RS03905	COG0084	hydrolase, TatD family'
ADP71_RS03930	COG0436	Aminotransferase
ADP71_RS03935	COG0583	DNA-binding transcription factor activity
ADP71_RS03945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADP71_RS03950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADP71_RS03975	COG2824	Alkylphosphonate utilization operon protein PhnA
ADP71_RS03980	COG0318	PFAM AMP-dependent synthetase and ligase
ADP71_RS04000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADP71_RS04005	COG0427	acetyl-CoA hydrolase
ADP71_RS04010	COG0859	PFAM glycosyl transferase family 9
ADP71_RS04025	COG1132	(ABC) transporter
ADP71_RS04035	COG2431	L-lysine efflux transmembrane transporter activity
ADP71_RS04050	COG1349	DNA-binding transcription factor activity
ADP71_RS04055	COG1132	(ABC) transporter
ADP71_RS04065	COG0477	Major facilitator Superfamily
ADP71_RS04070	COG0506	proline dehydrogenase activity
ADP71_RS04070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADP71_RS04070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADP71_RS04085	COG2267	carboxylic ester hydrolase activity
ADP71_RS04100	COG2321	neutral zinc metallopeptidase
ADP71_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS04120	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ADP71_RS04120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS04145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADP71_RS04150	COG2967	ApaG domain
ADP71_RS04160	COG1982	Orn Lys Arg decarboxylase major
ADP71_RS04215	COG0714	Associated with various cellular activities
ADP71_RS04235	COG2878	Part of a membrane complex involved in electron transport
ADP71_RS04275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADP71_RS04280	COG2171	N-acyltransferase activity
ADP71_RS04315	COG0028	Belongs to the TPP enzyme family
ADP71_RS04320	COG0440	acetolactate synthase activity
ADP71_RS04325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADP71_RS04365	COG1187	pseudouridine synthase activity
ADP71_RS04450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADP71_RS04455	COG2866	Carboxypeptidase
ADP71_RS04495	COG0006	proline dipeptidase activity
ADP71_RS04520	COG2841	Protein conserved in bacteria
ADP71_RS04530	COG1121	(ABC) transporter
ADP71_RS04535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADP71_RS04545	COG0408	coproporphyrinogen oxidase activity
ADP71_RS04560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADP71_RS04580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADP71_RS04590	COG2233	PERMEase
ADP71_RS04610	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ADP71_RS04615	COG3639	organic phosphonate transmembrane transporter activity
ADP71_RS04620	COG3624	Phosphonate C-P lyase system protein PhnG
ADP71_RS04630	COG3626	phosphonate metabolism
ADP71_RS04635	COG3627	carbon phosphorus lyase activity
ADP71_RS04640	COG4107	phosphonate C-P lyase system protein PhnK
ADP71_RS04645	COG4778	phosphonate C-P lyase system protein PhnL
ADP71_RS04650	COG3454	Phosphonate metabolism
ADP71_RS04660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ADP71_RS04685	COG0833	amino acid
ADP71_RS04690	COG2814	Major facilitator Superfamily
ADP71_RS04710	COG3384	dioxygenase
ADP71_RS04725	COG4607	ABC-type enterochelin transport system periplasmic component
ADP71_RS04730	COG4604	ABC transporter, ATP-binding protein
ADP71_RS04735	COG4605	iron ion homeostasis
ADP71_RS04740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADP71_RS04745	COG4772	TonB-dependent receptor
ADP71_RS04770	COG1643	Atp-dependent helicase
ADP71_RS04775	COG2304	oxidoreductase activity
ADP71_RS04780	COG2081	HI0933 family
ADP71_RS04790	COG0010	Belongs to the arginase family
ADP71_RS04805	COG2986	histidine ammonia-lyase
ADP71_RS04815	COG1584	GPR1 FUN34 yaaH family protein
ADP71_RS04835	COG0133	tryptophan synthase activity
ADP71_RS04850	COG0183	Belongs to the thiolase family
ADP71_RS04855	COG3243	poly(R)-hydroxyalkanoic acid synthase
ADP71_RS04860	COG0494	nUDIX hydrolase
ADP71_RS04865	COG1970	mechanosensitive ion channel activity
ADP71_RS04875	COG4166	transmembrane transport
ADP71_RS04905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADP71_RS04915	COG0704	Plays a role in the regulation of phosphate uptake
ADP71_RS04925	COG0393	Putative heavy-metal-binding
ADP71_RS04930	COG0393	Putative heavy-metal-binding
ADP71_RS04935	COG0513	Belongs to the DEAD box helicase family
ADP71_RS04945	COG2217	Heavy metal translocating P-type atpase
ADP71_RS04965	COG1561	YicC-like family, N-terminal region
ADP71_RS04970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADP71_RS04975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADP71_RS05000	COG1187	pseudouridine synthase activity
ADP71_RS05005	COG1802	Transcriptional regulator
ADP71_RS05025	COG3842	ATPase activity
ADP71_RS05030	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADP71_RS05035	COG1177	transmembrane transport
ADP71_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS05045	COG0235	Class ii aldolase
ADP71_RS05055	COG0300	oxidoreductase activity
ADP71_RS05065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADP71_RS05075	COG1408	metallophosphoesterase
ADP71_RS05085	COG1032	radical SAM domain protein
ADP71_RS05105	COG0210	DNA helicase
ADP71_RS05115	COG0617	tRNA 3'-terminal CCA addition
ADP71_RS05160	COG0492	ferredoxin-NADP+ reductase activity
ADP71_RS05165	COG0859	PFAM glycosyl transferase family 9
ADP71_RS05185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ADP71_RS05195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADP71_RS05210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADP71_RS05215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADP71_RS05220	COG0583	DNA-binding transcription factor activity
ADP71_RS05260	COG4774	siderophore transport
ADP71_RS05265	COG4615	Cyclic peptide transporter
ADP71_RS05275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADP71_RS05280	COG1120	ATPase activity
ADP71_RS05285	COG3949	Membrane
ADP71_RS05290	COG4239	(ABC) transporter, permease
ADP71_RS05295	COG4174	ABC transporter (Permease)
ADP71_RS05300	COG2833	Protein of unknown function (DUF455)
ADP71_RS05340	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ADP71_RS05350	COG1271	oxidase subunit
ADP71_RS05355	COG1294	oxidase, subunit
ADP71_RS05385	COG3048	D-serine ammonia-lyase activity
ADP71_RS05400	COG0583	DNA-binding transcription factor activity
ADP71_RS05410	COG2835	tetraacyldisaccharide 4'-kinase activity
ADP71_RS05430	COG0788	formyltetrahydrofolate deformylase activity
ADP71_RS05445	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADP71_RS05445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADP71_RS05460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADP71_RS05545	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ADP71_RS05600	COG0582	viral genome integration into host DNA
ADP71_RS05615	COG2873	o-acetylhomoserine
ADP71_RS05620	COG1187	pseudouridine synthase activity
ADP71_RS05625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADP71_RS05630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ADP71_RS05640	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ADP71_RS05670	COG3275	phosphorelay sensor kinase activity
ADP71_RS05690	COG0708	Exodeoxyribonuclease III
ADP71_RS05705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS05710	COG2814	Major facilitator Superfamily
ADP71_RS05720	COG1053	succinate dehydrogenase
ADP71_RS05745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADP71_RS05750	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS05755	COG1414	Transcriptional regulator
ADP71_RS05790	COG0277	FAD linked oxidase domain protein
ADP71_RS05815	COG0659	secondary active sulfate transmembrane transporter activity
ADP71_RS05830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADP71_RS05840	COG0793	Belongs to the peptidase S41A family
ADP71_RS05850	COG0067	glutamate synthase
ADP71_RS05850	COG0069	glutamate synthase activity
ADP71_RS05850	COG0070	glutamate synthase
ADP71_RS05855	COG0493	'glutamate synthase
ADP71_RS05860	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ADP71_RS05865	COG1671	Belongs to the UPF0178 family
ADP71_RS05880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADP71_RS05895	COG2271	Major facilitator Superfamily
ADP71_RS05920	COG4681	YaeQ
ADP71_RS05945	COG0714	Associated with various cellular activities
ADP71_RS05955	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ADP71_RS05965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADP71_RS06005	COG0386	Belongs to the glutathione peroxidase family
ADP71_RS06010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADP71_RS06030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADP71_RS06045	COG0583	DNA-binding transcription factor activity
ADP71_RS06055	COG1960	acyl-CoA dehydrogenase activity
ADP71_RS06060	COG1022	Amp-dependent synthetase and ligase
ADP71_RS06060	COG3320	Male sterility
ADP71_RS06065	COG1012	belongs to the aldehyde dehydrogenase family
ADP71_RS06070	COG1024	Enoyl-CoA hydratase
ADP71_RS06075	COG2814	Major facilitator Superfamily
ADP71_RS06085	COG3949	Membrane
ADP71_RS06105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADP71_RS06115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ADP71_RS06120	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADP71_RS06140	COG4172	Belongs to the ABC transporter superfamily
ADP71_RS06150	COG5544	Lipoprotein
ADP71_RS06160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADP71_RS06170	COG2813	Specifically methylates the guanine in position
ADP71_RS06170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADP71_RS06190	COG5510	response to toxic substance
ADP71_RS06205	COG2995	paraquat-inducible protein a
ADP71_RS06225	COG2153	protein acetylation
ADP71_RS06230	COG0697	spore germination
ADP71_RS06290	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ADP71_RS06310	COG0195	Participates in both transcription termination and antitermination
ADP71_RS06310	COG2251	uridine kinase activity
ADP71_RS06375	COG2837	iron assimilation
ADP71_RS06395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADP71_RS06400	COG0511	ligase activity, forming carbon-carbon bonds
ADP71_RS06405	COG0439	Biotin carboxylase
ADP71_RS06410	COG2264	protein methyltransferase activity
ADP71_RS06425	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ADP71_RS06480	COG0582	viral genome integration into host DNA
ADP71_RS06640	COG3949	Membrane
ADP71_RS06755	COG1278	Cold shock
ADP71_RS06820	COG3561	AntA/AntB antirepressor
ADP71_RS06995	COG1758	RNA polymerase activity
ADP71_RS07000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADP71_RS07010	COG1610	YqeY-like protein
ADP71_RS07035	COG0557	exoribonuclease II activity
ADP71_RS07045	COG2070	2-Nitropropane dioxygenase
ADP71_RS07055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADP71_RS07065	COG0633	Ferredoxin
ADP71_RS07075	COG4628	conserved protein (DUF2132)
ADP71_RS07080	COG2814	Major facilitator Superfamily
ADP71_RS07090	COG3135	benzoate transporter
ADP71_RS07095	COG1396	sequence-specific DNA binding
ADP71_RS07110	COG3878	Protein conserved in bacteria
ADP71_RS07120	COG1454	alcohol dehydrogenase
ADP71_RS07125	COG2610	gluconate transmembrane transporter activity
ADP71_RS07130	COG1414	Transcriptional regulator
ADP71_RS07135	COG0814	amino acid
ADP71_RS07160	COG0765	amino acid transport
ADP71_RS07165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADP71_RS07175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ADP71_RS07180	COG0347	Belongs to the P(II) protein family
ADP71_RS07190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADP71_RS07195	COG0183	Belongs to the thiolase family
ADP71_RS07200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADP71_RS07205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ADP71_RS07215	COG4829	muconolactone delta-isomerase
ADP71_RS07220	COG4948	Mandelate Racemase Muconate Lactonizing
ADP71_RS07225	COG0543	2 iron, 2 sulfur cluster binding
ADP71_RS07225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADP71_RS07230	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ADP71_RS07235	COG4638	Rieske (2fe-2S)
ADP71_RS07240	COG2207	Transcriptional regulator
ADP71_RS07245	COG2814	Major facilitator Superfamily
ADP71_RS07255	COG1012	belongs to the aldehyde dehydrogenase family
ADP71_RS07260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADP71_RS07315	COG0765	amino acid transport
ADP71_RS07320	COG1126	abc transporter atp-binding protein
ADP71_RS07345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADP71_RS07360	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADP71_RS07365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADP71_RS07380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADP71_RS07400	COG0583	DNA-binding transcription factor activity
ADP71_RS07440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADP71_RS07440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADP71_RS07445	COG0569	domain protein
ADP71_RS07450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADP71_RS07475	COG1960	acyl-CoA dehydrogenase activity
ADP71_RS07490	COG1047	Peptidyl-prolyl cis-trans
ADP71_RS07495	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ADP71_RS07505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADP71_RS07505	COG4651	solute:proton antiporter activity
ADP71_RS07510	COG0730	response to heat
ADP71_RS07520	COG2959	enzyme of heme biosynthesis
ADP71_RS07545	COG0745	RESPONSE REGULATOR receiver
ADP71_RS07550	COG5002	protein histidine kinase activity
ADP71_RS07560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADP71_RS07570	COG0596	Alpha beta hydrolase
ADP71_RS07580	COG0287	Prephenate dehydrogenase
ADP71_RS07605	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADP71_RS07615	COG0805	protein transport
ADP71_RS07620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADP71_RS07635	COG0140	phosphoribosyl-ATP diphosphatase activity
ADP71_RS07655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADP71_RS07675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADP71_RS07685	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADP71_RS07690	COG1137	ATPase activity
ADP71_RS07705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADP71_RS07735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADP71_RS07745	COG0572	uridine kinase
ADP71_RS07775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADP71_RS07790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADP71_RS07795	COG0297	glycogen (starch) synthase activity
ADP71_RS07800	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADP71_RS07805	COG0802	atpase or kinase
ADP71_RS07810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADP71_RS07820	COG1546	Belongs to the CinA family
ADP71_RS07820	COG1058	Belongs to the CinA family
ADP71_RS07830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADP71_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS07855	COG0109	protoheme IX farnesyltransferase activity
ADP71_RS07860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADP71_RS07865	COG1845	cytochrome c oxidase, subunit III
ADP71_RS07870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADP71_RS07875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ADP71_RS07880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADP71_RS07895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADP71_RS07925	COG0069	glutamate synthase activity
ADP71_RS07930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADP71_RS07940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADP71_RS07945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADP71_RS07950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADP71_RS07995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADP71_RS08015	COG0586	Pfam SNARE associated Golgi protein
ADP71_RS08030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADP71_RS08035	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ADP71_RS08040	COG1534	Rna-binding protein
ADP71_RS08060	COG2814	Major facilitator Superfamily
ADP71_RS08065	COG1196	nuclear chromosome segregation
ADP71_RS08065	COG0741	lytic transglycosylase activity
ADP71_RS08065	COG0739	heme binding
ADP71_RS08100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ADP71_RS08140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS08150	COG0312	modulator of DNA gyrase
ADP71_RS08165	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADP71_RS08170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADP71_RS08175	COG0004	ammonium transporteR
ADP71_RS08185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADP71_RS08190	COG1335	isochorismatase
ADP71_RS08205	COG3186	Phenylalanine-4-hydroxylase
ADP71_RS08245	COG1562	ergosterol biosynthetic process
ADP71_RS08260	COG1238	metal cluster binding
ADP71_RS08270	COG0300	oxidoreductase activity
ADP71_RS08275	COG0424	maF-like protein
ADP71_RS08280	COG1530	ribonuclease E activity
ADP71_RS08310	COG1448	Aminotransferase
ADP71_RS08320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADP71_RS08335	COG4206	TonB-dependent receptor
ADP71_RS08340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADP71_RS08350	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ADP71_RS08360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADP71_RS08410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADP71_RS08430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADP71_RS08465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ADP71_RS08470	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADP71_RS08475	COG1024	Enoyl-CoA hydratase
ADP71_RS08480	COG1024	Enoyl-CoA hydratase
ADP71_RS08525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADP71_RS08530	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADP71_RS08545	COG0697	spore germination
ADP71_RS08565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADP71_RS08570	COG0174	glutamine synthetase
ADP71_RS08575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADP71_RS08575	COG0519	Catalyzes the synthesis of GMP from XMP
ADP71_RS08595	COG0519	Catalyzes the synthesis of GMP from XMP
ADP71_RS08595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADP71_RS08620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADP71_RS08650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADP71_RS08670	COG0592	DNA-directed DNA polymerase activity
ADP71_RS08685	COG0419	ATPase involved in DNA repair
ADP71_RS08695	COG2608	mercury ion transmembrane transporter activity
ADP71_RS08700	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADP71_RS08705	COG0523	cobalamin synthesis protein
ADP71_RS08710	COG0735	belongs to the Fur family
ADP71_RS08745	COG0513	Belongs to the DEAD box helicase family
ADP71_RS08775	COG1187	pseudouridine synthase activity
ADP71_RS08780	COG1741	Belongs to the pirin family
ADP71_RS08790	COG0791	NLP P60 protein
ADP71_RS08810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADP71_RS08830	COG1358	cellular component organization or biogenesis
ADP71_RS08895	COG4245	von Willebrand factor, type A
ADP71_RS08910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADP71_RS08955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADP71_RS08980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADP71_RS08985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADP71_RS08995	COG2096	Adenosyltransferase
ADP71_RS09000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADP71_RS09025	COG2070	2-Nitropropane dioxygenase
ADP71_RS09070	COG0105	UTP biosynthetic process
ADP71_RS09075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ADP71_RS09100	COG1116	anion transmembrane transporter activity
ADP71_RS09105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADP71_RS09115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADP71_RS09120	COG0431	NADPH-dependent FMN reductase
ADP71_RS09125	COG2839	Protein conserved in bacteria
ADP71_RS09135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADP71_RS09145	COG1686	Belongs to the peptidase S11 family
ADP71_RS09155	COG0583	DNA-binding transcription factor activity
ADP71_RS09170	COG2329	Antibiotic biosynthesis monooxygenase
ADP71_RS09175	COG4771	TonB-dependent receptor
ADP71_RS09185	COG4558	Periplasmic binding protein
ADP71_RS09190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADP71_RS09195	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ADP71_RS09200	COG2271	Major facilitator Superfamily
ADP71_RS09205	COG2814	Major facilitator Superfamily
ADP71_RS09230	COG0412	Dienelactone hydrolase
ADP71_RS09235	COG0697	spore germination
ADP71_RS09240	COG3313	Fe-S protein
ADP71_RS09260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADP71_RS09265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADP71_RS09285	COG0084	hydrolase, TatD family'
ADP71_RS09290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ADP71_RS09290	COG0321	lipoyl(octanoyl) transferase activity
ADP71_RS09305	COG0326	Molecular chaperone. Has ATPase activity
ADP71_RS09330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADP71_RS09335	COG1702	phosphate starvation-inducible protein PhoH
ADP71_RS09350	COG4535	Mg2 and Co2 transporter CorC
ADP71_RS09355	COG2354	Protein conserved in bacteria
ADP71_RS09390	COG1122	ATPase activity
ADP71_RS09405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ADP71_RS09430	COG1505	serine-type exopeptidase activity
ADP71_RS09440	COG0312	modulator of DNA gyrase
ADP71_RS09460	COG0024	Methionine aminopeptidase
ADP71_RS09480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ADP71_RS09525	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADP71_RS09525	COG1902	pentaerythritol trinitrate reductase activity
ADP71_RS09575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADP71_RS09620	COG0318	PFAM AMP-dependent synthetase and ligase
ADP71_RS09625	COG2079	MmgE PrpD family protein
ADP71_RS09630	COG0372	Belongs to the citrate synthase family
ADP71_RS09635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ADP71_RS09675	COG2224	Isocitrate lyase
ADP71_RS09680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADP71_RS09685	COG2267	carboxylic ester hydrolase activity
ADP71_RS09695	COG4589	Belongs to the CDS family
ADP71_RS09700	COG0625	glutathione transferase activity
ADP71_RS09705	COG0308	aminopeptidase N
ADP71_RS09740	COG3206	protein involved in exopolysaccharide biosynthesis
ADP71_RS09740	COG0489	protein tyrosine kinase activity
ADP71_RS09750	COG1596	polysaccharide export
ADP71_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
ADP71_RS09775	COG4575	ribosome binding
ADP71_RS09780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADP71_RS09790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADP71_RS09800	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADP71_RS09805	COG0567	Dehydrogenase, E1 component
ADP71_RS09815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ADP71_RS09820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADP71_RS09825	COG1053	succinate dehydrogenase
ADP71_RS09845	COG0039	L-malate dehydrogenase activity
ADP71_RS09860	COG1194	a g-specific adenine glycosylase
ADP71_RS09865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADP71_RS09875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADP71_RS09880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ADP71_RS09950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADP71_RS09950	COG0678	peroxiredoxin activity
ADP71_RS09975	COG0545	Peptidyl-prolyl cis-trans isomerase
ADP71_RS09985	COG4771	TonB-dependent receptor
ADP71_RS09990	COG4771	TonB-dependent receptor
ADP71_RS09995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADP71_RS10000	COG2860	membrane
ADP71_RS10015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADP71_RS10025	COG3545	Serine hydrolase
ADP71_RS10050	COG2885	chlorophyll binding
ADP71_RS10080	COG0683	leucine binding
ADP71_RS10085	COG0583	DNA-binding transcription factor activity
ADP71_RS10090	COG0697	spore germination
ADP71_RS10095	COG5383	Protein conserved in bacteria
ADP71_RS10100	COG0277	FAD linked oxidase domain protein
ADP71_RS10100	COG0247	lactate metabolic process
ADP71_RS10110	COG1012	belongs to the aldehyde dehydrogenase family
ADP71_RS10125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS10135	COG0583	DNA-binding transcription factor activity
ADP71_RS10165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ADP71_RS10170	COG2895	sulfate adenylyltransferase (ATP) activity
ADP71_RS10175	COG0175	sulfate reduction
ADP71_RS10195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADP71_RS10195	COG1648	precorrin-2 dehydrogenase activity
ADP71_RS10200	COG1113	amino acid transport
ADP71_RS10210	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADP71_RS10215	COG2900	Belongs to the SlyX family
ADP71_RS10220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADP71_RS10255	COG0356	it plays a direct role in the translocation of protons across the membrane
ADP71_RS10270	COG1192	Involved in chromosome partitioning
ADP71_RS10295	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ADP71_RS10320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADP71_RS10325	COG1333	cytochrome c biogenesis protein
ADP71_RS10360	COG2159	amidohydrolase
ADP71_RS10400	COG0667	Aldo Keto reductase
ADP71_RS10430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADP71_RS10430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADP71_RS10465	COG0477	Major facilitator Superfamily
ADP71_RS10480	COG1560	Kdo2-lipid A biosynthetic process
ADP71_RS10520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADP71_RS10530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADP71_RS10535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ADP71_RS10555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADP71_RS10565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADP71_RS10575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADP71_RS10585	COG0581	inorganic phosphate transmembrane transporter activity
ADP71_RS10605	COG0306	phosphate transporter
ADP71_RS10620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADP71_RS10625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADP71_RS10630	COG1012	belongs to the aldehyde dehydrogenase family
ADP71_RS10635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADP71_RS10655	COG1960	acyl-CoA dehydrogenase activity
ADP71_RS10660	COG0861	Integral membrane protein TerC family
ADP71_RS10700	COG0714	Associated with various cellular activities
ADP71_RS10780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADP71_RS10875	COG1115	amino acid carrier protein
ADP71_RS10880	COG1802	Transcriptional regulator
ADP71_RS10905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADP71_RS10910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADP71_RS10940	COG0824	Thioesterase
ADP71_RS10965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADP71_RS10970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADP71_RS10975	COG1127	ABC transporter
ADP71_RS10985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADP71_RS11000	COG2252	PERMEase
ADP71_RS11005	COG1131	(ABC) transporter
ADP71_RS11010	COG0842	Transport permease protein
ADP71_RS11025	COG1999	signal sequence binding
ADP71_RS11030	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ADP71_RS11035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADP71_RS11050	COG1794	racemase activity, acting on amino acids and derivatives
ADP71_RS11055	COG1733	regulation of RNA biosynthetic process
ADP71_RS11060	COG4224	UPF0291 protein
ADP71_RS11070	COG0463	Glycosyl transferase, family 2
ADP71_RS11075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADP71_RS11085	COG0142	geranyltranstransferase activity
ADP71_RS11110	COG4221	oxidoreductase activity
ADP71_RS11145	COG0557	exoribonuclease II activity
ADP71_RS11180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADP71_RS11205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADP71_RS11245	COG2364	Membrane
ADP71_RS11255	COG2884	Cell division ATP-binding protein ftsE
ADP71_RS11270	COG0612	Peptidase, M16
ADP71_RS11295	COG1272	protein, Hemolysin III
ADP71_RS11300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADP71_RS11320	COG0859	PFAM glycosyl transferase family 9
ADP71_RS11325	COG2086	electron transfer activity
ADP71_RS11340	COG1739	Uncharacterized protein family UPF0029
ADP71_RS11365	COG2119	membrane
ADP71_RS11385	COG0210	DNA helicase
ADP71_RS11400	COG2962	Rard protein
ADP71_RS11420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADP71_RS11435	COG3279	Response regulator of the LytR AlgR family
ADP71_RS11440	COG0656	L-ascorbic acid biosynthetic process
ADP71_RS11455	COG0646	methionine synthase
ADP71_RS11455	COG1410	methionine synthase
ADP71_RS11465	COG1166	arginine decarboxylase activity
ADP71_RS11480	COG0625	glutathione transferase activity
ADP71_RS11495	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ADP71_RS11500	COG1011	Hydrolase
ADP71_RS11515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ADP71_RS11520	COG1742	UPF0060 membrane protein
ADP71_RS11540	COG0613	PHP domain protein
ADP71_RS11545	COG0009	L-threonylcarbamoyladenylate synthase
ADP71_RS11550	COG1994	Peptidase M50
ADP71_RS11560	COG0514	ATP-dependent DNA helicase (RecQ)
ADP71_RS11600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADP71_RS11630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADP71_RS11640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADP71_RS11670	COG1199	ATP-dependent helicase activity
ADP71_RS11700	COG0436	Aminotransferase
ADP71_RS11705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADP71_RS11720	COG1132	(ABC) transporter
ADP71_RS11730	COG2259	Doxx family
ADP71_RS11735	COG0583	DNA-binding transcription factor activity
ADP71_RS11740	COG4221	oxidoreductase activity
ADP71_RS11745	COG3237	CsbD-like
ADP71_RS11760	COG1752	Esterase of the alpha-beta hydrolase superfamily
ADP71_RS11765	COG2226	methyltransferase
ADP71_RS11775	COG1040	competence protein
ADP71_RS11790	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ADP71_RS11820	COG0489	protein tyrosine kinase activity
ADP71_RS11825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADP71_RS11845	COG1519	Transferase
ADP71_RS11890	COG1247	-acetyltransferase
ADP71_RS11915	COG4774	siderophore transport
ADP71_RS11920	COG3128	pkhd-type hydroxylase
ADP71_RS11930	COG1956	GAF domain-containing protein
ADP71_RS12010	COG4197	protein conserved in bacteria, prophage-related
ADP71_RS12080	COG4695	Portal protein
ADP71_RS12230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADP71_RS12245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ADP71_RS12255	COG0788	formyltetrahydrofolate deformylase activity
ADP71_RS12260	COG2832	Protein of unknown function (DUF454)
ADP71_RS12280	COG0509	glycine decarboxylation via glycine cleavage system
ADP71_RS12285	COG4682	membrane
ADP71_RS12300	COG2814	Major facilitator Superfamily
ADP71_RS12380	COG1280	lysine exporter protein (LysE YggA)
ADP71_RS12395	COG0739	heme binding
ADP71_RS12420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADP71_RS12430	COG2201	protein-glutamate methylesterase activity
ADP71_RS12435	COG2198	Histidine kinase
ADP71_RS12435	COG0643	Histidine kinase
ADP71_RS12445	COG0288	reversible hydration of carbon dioxide
ADP71_RS12455	COG0799	negative regulation of ribosome biogenesis
ADP71_RS12480	COG2030	dehydratase
ADP71_RS12485	COG5002	protein histidine kinase activity
ADP71_RS12495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADP71_RS12500	COG1879	ABC-type sugar transport system periplasmic component
ADP71_RS12505	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADP71_RS12515	COG1869	D-ribose catabolic process
ADP71_RS12530	COG0758	DNA mediated transformation
ADP71_RS12535	COG1652	LysM domain
ADP71_RS12545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADP71_RS12550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADP71_RS12550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADP71_RS12560	COG5000	phosphorelay sensor kinase activity
ADP71_RS12565	COG2204	response regulator
ADP71_RS12580	COG0742	ribosomal rna small subunit methyltransferase
ADP71_RS12585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADP71_RS12710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADP71_RS12715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADP71_RS12775	COG0200	Binds to the 23S rRNA
ADP71_RS12780	COG0201	protein transport
ADP71_RS12790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADP71_RS12835	COG0765	amino acid transport
ADP71_RS12840	COG0765	amino acid transport
ADP71_RS12845	COG1126	abc transporter atp-binding protein
ADP71_RS12850	COG1113	amino acid transport
ADP71_RS12855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADP71_RS12860	COG2715	membrane protein required for spore maturation
ADP71_RS12895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY