locus-tag	class	description
AUC63_RS00050	COG2176	DNA-directed DNA polymerase activity
AUC63_RS00055	COG0442	prolyl-tRNA aminoacylation
AUC63_RS00060	COG0750	zinc metalloprotease
AUC63_RS00065	COG4589	Belongs to the CDS family
AUC63_RS00070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUC63_RS00075	COG0561	phosphatase activity
AUC63_RS00080	COG2246	polysaccharide biosynthetic process
AUC63_RS00105	COG1811	Na channel or pump
AUC63_RS00110	COG1979	alcohol dehydrogenase
AUC63_RS00120	COG1174	glycine betaine transport
AUC63_RS00140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUC63_RS00145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_RS00145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_RS00150	COG0307	riboflavin synthase, alpha
AUC63_RS00160	COG2076	Multidrug Resistance protein
AUC63_RS00165	COG2076	Multidrug Resistance protein
AUC63_RS00170	COG1435	thymidine kinase activity
AUC63_RS00185	COG1307	EDD domain protein, DegV family
AUC63_RS00190	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS00195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC63_RS00200	COG2814	Major facilitator Superfamily
AUC63_RS00215	COG1228	amidohydrolase
AUC63_RS00220	COG4166	transmembrane transport
AUC63_RS00265	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AUC63_RS00270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUC63_RS00280	COG2252	PERMEase
AUC63_RS00290	COG0352	thiamine-phosphate diphosphorylase activity
AUC63_RS00295	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AUC63_RS00305	COG2814	Major facilitator Superfamily
AUC63_RS00310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUC63_RS00320	COG2188	Transcriptional regulator
AUC63_RS00330	COG0577	efflux transmembrane transporter activity
AUC63_RS00330	COG1136	(ABC) transporter
AUC63_RS00340	COG0561	phosphatase activity
AUC63_RS00345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUC63_RS00345	COG2169	Transcriptional regulator
AUC63_RS00350	COG0561	phosphatase activity
AUC63_RS00370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUC63_RS00375	COG0772	Belongs to the SEDS family
AUC63_RS00385	COG1077	Cell shape determining protein MreB Mrl
AUC63_RS00390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC63_RS00395	COG1079	Belongs to the binding-protein-dependent transport system permease family
AUC63_RS00400	COG4603	Belongs to the binding-protein-dependent transport system permease family
AUC63_RS00405	COG3845	ABC transporter
AUC63_RS00410	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS00415	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_RS00425	COG0640	Transcriptional regulator
AUC63_RS00430	COG0628	permease
AUC63_RS00435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_RS00455	COG0386	Belongs to the glutathione peroxidase family
AUC63_RS00460	COG0588	phosphoglycerate mutase activity
AUC63_RS00475	COG0492	ferredoxin-NADP+ reductase activity
AUC63_RS00490	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS00495	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS00505	COG2832	Protein of unknown function (DUF454)
AUC63_RS00530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC63_RS00540	COG2814	Major facilitator Superfamily
AUC63_RS00545	COG0305	Participates in initiation and elongation during chromosome replication
AUC63_RS00550	COG0359	binds to the 23S rRNA
AUC63_RS00560	COG4608	Belongs to the ABC transporter superfamily
AUC63_RS00565	COG0444	Belongs to the ABC transporter superfamily
AUC63_RS00570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_RS00575	COG0601	transmembrane transport
AUC63_RS00580	COG4166	transmembrane transport
AUC63_RS00585	COG0765	amino acid transport
AUC63_RS00590	COG0765	amino acid transport
AUC63_RS00595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_RS00600	COG1126	abc transporter atp-binding protein
AUC63_RS00615	COG0194	GDP metabolic process
AUC63_RS00620	COG1268	BioY protein
AUC63_RS00625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AUC63_RS00625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AUC63_RS00650	COG2211	Major facilitator Superfamily
AUC63_RS00655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AUC63_RS00670	COG3973	AAA domain
AUC63_RS00690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AUC63_RS00700	COG1696	Membrane protein involved in D-alanine export
AUC63_RS00720	COG2337	Toxic component of a toxin-antitoxin (TA) module
AUC63_RS00735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUC63_RS00740	COG0504	CTP synthase activity
AUC63_RS00750	COG3343	RNA polymerase activity
AUC63_RS00755	COG0561	phosphatase activity
AUC63_RS00760	COG1078	dGTPase activity
AUC63_RS00770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUC63_RS00775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AUC63_RS00795	COG0745	RESPONSE REGULATOR receiver
AUC63_RS00825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUC63_RS00830	COG0629	single-stranded DNA binding
AUC63_RS00835	COG0360	Binds together with S18 to 16S ribosomal RNA
AUC63_RS00850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC63_RS00860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC63_RS00865	COG1051	belongs to the nudix hydrolase family
AUC63_RS00880	COG2814	Major facilitator Superfamily
AUC63_RS00885	COG1064	alcohol dehydrogenase
AUC63_RS00890	COG1074	ATP-dependent DNA helicase activity
AUC63_RS00895	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AUC63_RS00910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC63_RS00915	COG0531	amino acid
AUC63_RS00920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AUC63_RS00930	COG1902	pentaerythritol trinitrate reductase activity
AUC63_RS00935	COG0626	cystathionine gamma-synthase activity
AUC63_RS00950	COG2244	polysaccharide biosynthetic process
AUC63_RS00960	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS00965	COG0495	leucyl-tRNA aminoacylation
AUC63_RS00970	COG0671	phosphoesterase, PA-phosphatase related
AUC63_RS00980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_RS01005	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS01020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC63_RS01030	COG2801	Transposase and inactivated derivatives
AUC63_RS01040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC63_RS01050	COG0024	Methionine aminopeptidase
AUC63_RS01060	COG1316	TRANSCRIPTIONal
AUC63_RS01070	COG2205	protein histidine kinase activity
AUC63_RS01075	COG0745	RESPONSE REGULATOR receiver
AUC63_RS01080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC63_RS01095	COG2207	Transcriptional regulator
AUC63_RS01115	COG0308	aminopeptidase N
AUC63_RS01120	COG0833	amino acid
AUC63_RS01125	COG2040	homocysteine
AUC63_RS01135	COG0542	response to heat
AUC63_RS01150	COG0395	ABC-type sugar transport system, permease component
AUC63_RS01155	COG1175	transmembrane transport
AUC63_RS01160	COG3842	ATPase activity
AUC63_RS01270	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS01300	COG2084	Dehydrogenase
AUC63_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_RS01315	COG1620	l-lactate permease
AUC63_RS01320	COG4989	oxidoreductase activity
AUC63_RS01325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC63_RS01330	COG2233	PERMEase
AUC63_RS01345	COG1956	GAF domain-containing protein
AUC63_RS01360	COG1132	(ABC) transporter
AUC63_RS01370	COG0747	negative chemotaxis
AUC63_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_RS01380	COG0601	transmembrane transport
AUC63_RS01385	COG4608	Belongs to the ABC transporter superfamily
AUC63_RS01390	COG0444	Belongs to the ABC transporter superfamily
AUC63_RS01395	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AUC63_RS01400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AUC63_RS01405	COG2211	Major facilitator Superfamily
AUC63_RS01405	COG2190	(PTS) system
AUC63_RS01425	COG0436	Aminotransferase
AUC63_RS01435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_RS01440	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS01445	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS01450	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC63_RS01455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_RS01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUC63_RS01475	COG1216	Glycosyl transferase, family 2
AUC63_RS01490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUC63_RS01535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AUC63_RS01540	COG1737	Transcriptional regulator
AUC63_RS01550	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS01555	COG2261	transglycosylase associated protein
AUC63_RS01620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUC63_RS01625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AUC63_RS01640	COG0037	tRNA processing
AUC63_RS01650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AUC63_RS01655	COG2244	polysaccharide biosynthetic process
AUC63_RS01660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AUC63_RS01665	COG0193	aminoacyl-tRNA hydrolase activity
AUC63_RS01675	COG0058	SHG alpha-glucan phosphorylase activity
AUC63_RS01680	COG0297	glycogen (starch) synthase activity
AUC63_RS01685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUC63_RS01695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUC63_RS01700	COG1511	domain protein
AUC63_RS01700	COG1511	domain protein
AUC63_RS01705	COG1309	transcriptional regulator
AUC63_RS01720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_RS01725	COG0477	Major facilitator Superfamily
AUC63_RS01740	COG0667	Aldo Keto reductase
AUC63_RS01750	COG2115	Belongs to the xylose isomerase family
AUC63_RS01760	COG2211	Major facilitator Superfamily
AUC63_RS01765	COG3507	Belongs to the glycosyl hydrolase 43 family
AUC63_RS01790	COG2818	Glycosylase
AUC63_RS01795	COG1968	undecaprenyl-diphosphatase activity
AUC63_RS01810	COG1695	Transcriptional regulator
AUC63_RS01815	COG1983	PspC domain protein
AUC63_RS01820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AUC63_RS01825	COG0737	Belongs to the 5'-nucleotidase family
AUC63_RS01840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AUC63_RS01855	COG1263	PTS System
AUC63_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_RS01860	COG1316	TRANSCRIPTIONal
AUC63_RS01870	COG2131	deaminase
AUC63_RS01875	COG4466	Protein conserved in bacteria
AUC63_RS01880	COG1253	flavin adenine dinucleotide binding
AUC63_RS01885	COG1253	flavin adenine dinucleotide binding
AUC63_RS01890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUC63_RS01895	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AUC63_RS01900	COG0084	hydrolase, TatD family'
AUC63_RS01910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_RS01910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_RS01970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AUC63_RS01990	COG1368	sulfuric ester hydrolase activity
AUC63_RS01995	COG2153	protein acetylation
AUC63_RS02010	COG0187	DNA topoisomerase II activity
AUC63_RS02015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUC63_RS02020	COG2501	S4 domain
AUC63_RS02025	COG0592	DNA-directed DNA polymerase activity
AUC63_RS02030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUC63_RS02035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AUC63_RS02040	COG0594	ribonuclease P activity
AUC63_RS02045	COG0706	membrane insertase activity
AUC63_RS02055	COG1120	ATPase activity
AUC63_RS02065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AUC63_RS02080	COG0569	domain protein
AUC63_RS02085	COG1113	amino acid transport
AUC63_RS02105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC63_RS02115	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_RS02125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AUC63_RS02130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUC63_RS02140	COG1136	(ABC) transporter
AUC63_RS02145	COG0577	efflux transmembrane transporter activity
AUC63_RS02150	COG2409	Drug exporters of the RND superfamily
AUC63_RS02150	COG1033	growth of symbiont in host cell
AUC63_RS02155	COG0561	phosphatase activity
AUC63_RS02165	COG0328	RNA-DNA hybrid ribonuclease activity
AUC63_RS02185	COG3152	Membrane
AUC63_RS02190	COG2252	PERMEase
AUC63_RS02230	COG1881	PFAM PEBP family protein
AUC63_RS02300	COG1476	TRANSCRIPTIONal
AUC63_RS02325	COG0517	IMP dehydrogenase activity
AUC63_RS02325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC63_RS02330	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS02350	COG0697	spore germination
AUC63_RS02365	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS02370	COG0137	argininosuccinate synthase activity
AUC63_RS02375	COG0165	Argininosuccinate lyase
AUC63_RS02380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUC63_RS02385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUC63_RS02395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AUC63_RS02400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC63_RS02405	COG0505	Belongs to the CarA family
AUC63_RS02410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC63_RS02430	COG1131	(ABC) transporter
AUC63_RS02450	COG0789	Transcriptional regulator
AUC63_RS02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_RS02475	COG0697	spore germination
AUC63_RS02480	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS02500	COG1846	Transcriptional regulator
AUC63_RS02505	COG1132	(ABC) transporter
AUC63_RS02515	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS02525	COG4619	ABC transporter
AUC63_RS02530	COG0390	transport system, permease component
AUC63_RS02540	COG1131	(ABC) transporter
AUC63_RS02550	COG1126	abc transporter atp-binding protein
AUC63_RS02555	COG0765	amino acid transport
AUC63_RS02560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_RS02565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_RS02570	COG1254	Belongs to the acylphosphatase family
AUC63_RS02580	COG0392	lysyltransferase activity
AUC63_RS02580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUC63_RS02590	COG0628	permease
AUC63_RS02620	COG1113	amino acid transport
AUC63_RS02645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AUC63_RS02660	COG2855	membrane
AUC63_RS02665	COG3620	sequence-specific DNA binding
AUC63_RS02675	COG2855	membrane
AUC63_RS02680	COG0583	DNA-binding transcription factor activity
AUC63_RS02690	COG2070	2-Nitropropane dioxygenase
AUC63_RS02705	COG1228	amidohydrolase
AUC63_RS02710	COG0531	amino acid
AUC63_RS02720	COG3223	Belongs to the PsiE family
AUC63_RS02730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC63_RS02740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AUC63_RS02750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC63_RS02755	COG4166	transmembrane transport
AUC63_RS02760	COG2267	carboxylic ester hydrolase activity
AUC63_RS02765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AUC63_RS02775	COG0477	Major facilitator Superfamily
AUC63_RS02780	COG4975	Glucose uptake
AUC63_RS02790	COG0531	amino acid
AUC63_RS02795	COG1113	amino acid transport
AUC63_RS02800	COG0531	amino acid
AUC63_RS02805	COG0252	asparaginase activity
AUC63_RS02810	COG4443	Transcriptional Coactivator p15 (PC4)
AUC63_RS02820	COG2226	methyltransferase
AUC63_RS02825	COG1335	isochorismatase
AUC63_RS02830	COG2050	protein possibly involved in aromatic compounds catabolism
AUC63_RS02835	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUC63_RS02840	COG0318	PFAM AMP-dependent synthetase and ligase
AUC63_RS02855	COG0745	RESPONSE REGULATOR receiver
AUC63_RS02860	COG5002	protein histidine kinase activity
AUC63_RS02900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC63_RS02905	COG1194	a g-specific adenine glycosylase
AUC63_RS02915	COG0357	Ribosomal RNA small subunit methyltransferase G
AUC63_RS02920	COG1192	Involved in chromosome partitioning
AUC63_RS02925	COG1475	DNA binding
AUC63_RS02930	COG4481	Protein conserved in bacteria
AUC63_RS02935	COG0012	GTP binding
AUC63_RS02945	COG0745	RESPONSE REGULATOR receiver
AUC63_RS02955	COG1686	Belongs to the peptidase S11 family
AUC63_RS03005	COG3104	oligopeptide transport
AUC63_RS03010	COG0477	Major facilitator Superfamily
AUC63_RS03015	COG4975	Glucose uptake
AUC63_RS03060	COG3091	SprT-like family
AUC63_RS03065	COG2755	lipolytic protein G-D-S-L family
AUC63_RS03065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AUC63_RS03080	COG1846	Transcriptional regulator
AUC63_RS03090	COG1121	(ABC) transporter
AUC63_RS03095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC63_RS03100	COG1373	ATPase (AAA superfamily
AUC63_RS03105	COG0488	(ABC) transporter
AUC63_RS03110	COG0534	Mate efflux family protein
AUC63_RS03125	COG3940	Belongs to the glycosyl hydrolase 43 family
AUC63_RS03150	COG2160	L-arabinose isomerase activity
AUC63_RS03155	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS03190	COG0765	amino acid transport
AUC63_RS03220	COG1215	transferase activity, transferring glycosyl groups
AUC63_RS03225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AUC63_RS03230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AUC63_RS03245	COG1418	mRNA catabolic process
AUC63_RS03250	COG2814	Major facilitator Superfamily
AUC63_RS03255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC63_RS03260	COG2188	Transcriptional regulator
AUC63_RS03265	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AUC63_RS03280	COG0463	Glycosyl transferase, family 2
AUC63_RS03280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AUC63_RS03300	COG1442	glycosyl transferase family 8
AUC63_RS03300	COG1216	Glycosyl transferase, family 2
AUC63_RS03305	COG1215	transferase activity, transferring glycosyl groups
AUC63_RS03310	COG2801	Transposase and inactivated derivatives
AUC63_RS03325	COG5039	Polysaccharide pyruvyl transferase
AUC63_RS03365	COG3590	peptidase
AUC63_RS03370	COG1454	alcohol dehydrogenase
AUC63_RS03370	COG1012	belongs to the aldehyde dehydrogenase family
AUC63_RS03380	COG0708	Exodeoxyribonuclease III
AUC63_RS03400	COG0588	phosphoglycerate mutase activity
AUC63_RS03405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AUC63_RS03420	COG1132	(ABC) transporter
AUC63_RS03425	COG1132	(ABC) transporter
AUC63_RS03450	COG0110	maltose O-acetyltransferase activity
AUC63_RS03460	COG1482	cell wall glycoprotein biosynthetic process
AUC63_RS03465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC63_RS03470	COG3442	glutamine amidotransferase
AUC63_RS03480	COG1435	thymidine kinase activity
AUC63_RS03485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUC63_RS03490	COG2890	protein-(glutamine-N5) methyltransferase activity
AUC63_RS03495	COG0009	L-threonylcarbamoyladenylate synthase
AUC63_RS03500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUC63_RS03505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AUC63_RS03510	COG0702	epimerase
AUC63_RS03520	COG2233	PERMEase
AUC63_RS03525	COG0356	it plays a direct role in the translocation of protons across the membrane
AUC63_RS03530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC63_RS03535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUC63_RS03540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC63_RS03545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUC63_RS03550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUC63_RS03555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUC63_RS03560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUC63_RS03565	COG1876	peptidase activity
AUC63_RS03570	COG1428	Deoxynucleoside kinase
AUC63_RS03575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUC63_RS03600	COG4463	regulation of RNA biosynthetic process
AUC63_RS03605	COG0542	response to heat
AUC63_RS03610	COG0085	RNA polymerase activity
AUC63_RS03625	COG1979	alcohol dehydrogenase
AUC63_RS03640	COG1309	transcriptional regulator
AUC63_RS03645	COG0500	methyltransferase
AUC63_RS03690	COG3620	sequence-specific DNA binding
AUC63_RS03700	COG2807	transmembrane transport
AUC63_RS03710	COG2813	Specifically methylates the guanine in position
AUC63_RS03715	COG0590	tRNA wobble adenosine to inosine editing
AUC63_RS03725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AUC63_RS03750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUC63_RS03755	COG3870	Protein conserved in bacteria
AUC63_RS03775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUC63_RS03780	COG1214	PFAM Peptidase M22, glycoprotease
AUC63_RS03785	COG0456	acetyltransferase
AUC63_RS03795	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUC63_RS03800	COG0142	geranyltranstransferase activity
AUC63_RS03805	COG0051	transcription antitermination factor activity, RNA binding
AUC63_RS03810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUC63_RS03820	COG0089	rRNA binding
AUC63_RS03825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUC63_RS03830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUC63_RS03835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUC63_RS03840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUC63_RS03845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUC63_RS03850	COG0255	Belongs to the universal ribosomal protein uL29 family
AUC63_RS03860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUC63_RS03865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUC63_RS03870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUC63_RS03875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUC63_RS03880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUC63_RS03885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AUC63_RS03890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUC63_RS03895	COG1841	ribosomal large subunit assembly
AUC63_RS03900	COG0200	Binds to the 23S rRNA
AUC63_RS03915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUC63_RS03920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUC63_RS03925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AUC63_RS03930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUC63_RS03935	COG0202	RNA polymerase activity
AUC63_RS03940	COG0203	ribosomal protein L17
AUC63_RS03965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AUC63_RS03980	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AUC63_RS04005	COG0583	DNA-binding transcription factor activity
AUC63_RS04010	COG0114	fumarate hydratase activity
AUC63_RS04015	COG1053	succinate dehydrogenase
AUC63_RS04020	COG0471	metal ion transport
AUC63_RS04025	COG0039	L-malate dehydrogenase activity
AUC63_RS04030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUC63_RS04035	COG0215	cysteine-tRNA ligase activity
AUC63_RS04040	COG0626	cystathionine gamma-synthase activity
AUC63_RS04045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AUC63_RS04050	COG1464	Belongs to the NlpA lipoprotein family
AUC63_RS04055	COG1854	S-ribosylhomocysteine lyase activity
AUC63_RS04060	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AUC63_RS04065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC63_RS04080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUC63_RS04085	COG0250	Participates in transcription elongation, termination and antitermination
AUC63_RS04090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUC63_RS04095	COG0081	regulation of translation
AUC63_RS04100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUC63_RS04105	COG0222	ribosome binding
AUC63_RS04115	COG1121	(ABC) transporter
AUC63_RS04120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC63_RS04125	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUC63_RS04130	COG1252	NADH dehydrogenase
AUC63_RS04140	COG1122	ATPase activity
AUC63_RS04145	COG1122	ATPase activity
AUC63_RS04155	COG0101	tRNA pseudouridine synthase activity
AUC63_RS04160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUC63_RS04170	COG4221	oxidoreductase activity
AUC63_RS04190	COG0028	Belongs to the TPP enzyme family
AUC63_RS04200	COG1573	uracil-dna glycosylase
AUC63_RS04215	COG0366	Alpha amylase catalytic
AUC63_RS04225	COG0671	phosphoesterase, PA-phosphatase related
AUC63_RS04235	COG2814	Major facilitator Superfamily
AUC63_RS04240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC63_RS04250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AUC63_RS04255	COG1481	regulation of sporulation
AUC63_RS04260	COG0740	serine-type endopeptidase activity
AUC63_RS04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_RS04275	COG1263	PTS System
AUC63_RS04285	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC63_RS04305	COG0039	L-malate dehydrogenase activity
AUC63_RS04310	COG0028	Belongs to the TPP enzyme family
AUC63_RS04315	COG3527	Alpha-acetolactate decarboxylase
AUC63_RS04325	COG3942	CHAP domain
AUC63_RS04325	COG1388	LysM domain
AUC63_RS04330	COG0791	NLP P60 protein
AUC63_RS04340	COG0756	dUTP diphosphatase activity
AUC63_RS04350	COG4956	integral membrane protein (PIN domain superfamily)
AUC63_RS04360	COG0653	protein targeting
AUC63_RS04365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUC63_RS04385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC63_RS04395	COG1733	regulation of RNA biosynthetic process
AUC63_RS04400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUC63_RS04405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_RS04405	COG0072	phenylalanine-tRNA ligase activity
AUC63_RS04410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AUC63_RS04415	COG0514	ATP-dependent DNA helicase (RecQ)
AUC63_RS04420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUC63_RS04430	COG0768	penicillin binding
AUC63_RS04435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AUC63_RS04450	COG1940	carbohydrate kinase activity
AUC63_RS04455	COG5632	N-Acetylmuramoyl-L-alanine amidase
AUC63_RS04455	COG3409	Peptidoglycan-binding domain 1 protein
AUC63_RS04460	COG3942	CHAP domain
AUC63_RS04480	COG0584	glycerophosphoryl diester phosphodiesterase
AUC63_RS04485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUC63_RS04490	COG0789	Transcriptional regulator
AUC63_RS04495	COG0174	glutamine synthetase
AUC63_RS04520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUC63_RS04525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUC63_RS04530	COG1472	Belongs to the glycosyl hydrolase 3 family
AUC63_RS04540	COG1132	(ABC) transporter
AUC63_RS04545	COG0778	Nitroreductase
AUC63_RS04550	COG1169	isochorismate synthase
AUC63_RS04555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUC63_RS04560	COG0596	Alpha beta hydrolase
AUC63_RS04565	COG4948	Mandelate Racemase Muconate Lactonizing
AUC63_RS04585	COG0737	Belongs to the 5'-nucleotidase family
AUC63_RS04590	COG4470	Protein conserved in bacteria
AUC63_RS04595	COG0647	UMP catabolic process
AUC63_RS04600	COG4166	transmembrane transport
AUC63_RS04605	COG0673	inositol 2-dehydrogenase activity
AUC63_RS04630	COG0573	inorganic phosphate transmembrane transporter activity
AUC63_RS04635	COG0581	inorganic phosphate transmembrane transporter activity
AUC63_RS04640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC63_RS04645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC63_RS04650	COG0704	Plays a role in the regulation of phosphate uptake
AUC63_RS04655	COG2137	regulation of response to DNA damage stimulus
AUC63_RS04680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AUC63_RS04690	COG5506	Protein of unknown function (DUF1694)
AUC63_RS04700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AUC63_RS04810	COG1272	protein, Hemolysin III
AUC63_RS04845	COG0525	valine-tRNA ligase activity
AUC63_RS04855	COG0285	dihydrofolate synthase activity
AUC63_RS04875	COG0488	(ABC) transporter
AUC63_RS04880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUC63_RS04885	COG0459	protein refolding
AUC63_RS04890	COG0531	amino acid
AUC63_RS04900	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUC63_RS04905	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AUC63_RS04910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AUC63_RS04920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUC63_RS04925	COG1713	HD superfamily hydrolase involved in NAD metabolism
AUC63_RS04930	COG0799	negative regulation of ribosome biogenesis
AUC63_RS04935	COG2226	methyltransferase
AUC63_RS04940	COG1323	Belongs to the UPF0348 family
AUC63_RS04950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AUC63_RS04955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AUC63_RS05045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUC63_RS05055	COG0363	glucosamine-6-phosphate deaminase activity
AUC63_RS05060	COG0776	regulation of translation
AUC63_RS05070	COG0577	efflux transmembrane transporter activity
AUC63_RS05075	COG1136	(ABC) transporter
AUC63_RS05090	COG4720	Psort location CytoplasmicMembrane, score
AUC63_RS05095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUC63_RS05100	COG1570	exodeoxyribonuclease VII activity
AUC63_RS05110	COG0142	geranyltranstransferase activity
AUC63_RS05115	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AUC63_RS05120	COG1438	arginine binding
AUC63_RS05125	COG0497	DNA recombination
AUC63_RS05135	COG0194	GDP metabolic process
AUC63_RS05145	COG0586	Pfam SNARE associated Golgi protein
AUC63_RS05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC63_RS05155	COG1098	S1 RNA binding domain
AUC63_RS05270	COG4684	Psort location CytoplasmicMembrane, score
AUC63_RS05275	COG1271	oxidase subunit
AUC63_RS05280	COG1294	oxidase, subunit
AUC63_RS05285	COG4988	ABC transporter
AUC63_RS05290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AUC63_RS05295	COG1388	LysM domain
AUC63_RS05295	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_RS05300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AUC63_RS05315	COG1278	Cold shock
AUC63_RS05320	COG0494	nUDIX hydrolase
AUC63_RS05330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AUC63_RS05335	COG0346	lactoylglutathione lyase activity
AUC63_RS05340	COG0400	carboxylic ester hydrolase activity
AUC63_RS05350	COG0741	lytic transglycosylase activity
AUC63_RS05370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AUC63_RS05375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC63_RS05380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC63_RS05390	COG4120	Belongs to the binding-protein-dependent transport system permease family
AUC63_RS05400	COG0038	chloride channel
AUC63_RS05405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC63_RS05410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC63_RS05415	COG1307	EDD domain protein, DegV family
AUC63_RS05420	COG2190	(PTS) system
AUC63_RS05420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_RS05420	COG1263	PTS System
AUC63_RS05435	COG2003	Belongs to the UPF0758 family
AUC63_RS05440	COG1077	Cell shape determining protein MreB Mrl
AUC63_RS05450	COG3338	carbonate dehydratase activity
AUC63_RS05460	COG0765	amino acid transport
AUC63_RS05465	COG1126	abc transporter atp-binding protein
AUC63_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_RS05475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_RS05475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_RS05480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AUC63_RS05485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AUC63_RS05490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUC63_RS05505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUC63_RS05515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUC63_RS05520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AUC63_RS05525	COG0138	bifunctional purine biosynthesis protein purh
AUC63_RS05530	COG0151	Belongs to the GarS family
AUC63_RS05535	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AUC63_RS05550	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_RS05565	COG0833	amino acid
AUC63_RS05575	COG2264	protein methyltransferase activity
AUC63_RS05580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AUC63_RS05590	COG2001	Belongs to the MraZ family
AUC63_RS05595	COG0275	rRNA processing
AUC63_RS05605	COG0768	penicillin binding
AUC63_RS05610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUC63_RS05615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUC63_RS05620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUC63_RS05625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AUC63_RS05630	COG0849	cell division
AUC63_RS05640	COG1799	cell septum assembly
AUC63_RS05655	COG3599	regulation of cell shape
AUC63_RS05675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_RS05680	COG0217	transcriptional regulatory protein
AUC63_RS05685	COG2252	PERMEase
AUC63_RS05690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AUC63_RS05730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC63_RS05735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AUC63_RS05740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUC63_RS05745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUC63_RS05745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC63_RS05750	COG0631	protein serine/threonine phosphatase activity
AUC63_RS05755	COG0515	serine threonine protein kinase
AUC63_RS05755	COG2815	serine threonine protein kinase
AUC63_RS05760	COG1162	GTPase activity
AUC63_RS05765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUC63_RS05775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUC63_RS05785	COG1461	Dihydroxyacetone kinase
AUC63_RS05800	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS05810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AUC63_RS05815	COG0416	fatty acid biosynthetic process
AUC63_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC63_RS05825	COG0571	ribonuclease III activity
AUC63_RS05830	COG1196	nuclear chromosome segregation
AUC63_RS05835	COG0552	protein localization to endoplasmic reticulum
AUC63_RS05840	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AUC63_RS05845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AUC63_RS05860	COG0228	four-way junction DNA binding
AUC63_RS05875	COG0588	phosphoglycerate mutase activity
AUC63_RS05880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUC63_RS05885	COG0336	Belongs to the RNA methyltransferase TrmD family
AUC63_RS05890	COG0335	large ribosomal subunit rRNA binding
AUC63_RS05900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_RS05905	COG1942	4-Oxalocrotonate Tautomerase
AUC63_RS05910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUC63_RS05920	COG1428	Deoxynucleoside kinase
AUC63_RS05925	COG1970	mechanosensitive ion channel activity
AUC63_RS05930	COG0561	phosphatase activity
AUC63_RS05995	COG3853	Toxic anion resistance protein (TelA)
AUC63_RS06000	COG1393	Belongs to the ArsC family
AUC63_RS06005	COG4862	establishment of competence for transformation
AUC63_RS06010	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS06015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_RS06020	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC63_RS06025	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS06030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_RS06040	COG1164	Oligoendopeptidase f
AUC63_RS06045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC63_RS06060	COG1609	Transcriptional regulator
AUC63_RS06065	COG0006	proline dipeptidase activity
AUC63_RS06135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AUC63_RS06140	COG3425	synthase
AUC63_RS06155	COG0860	N-Acetylmuramoyl-L-alanine amidase
AUC63_RS06160	COG0124	histidyl-tRNA synthetase
AUC63_RS06165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AUC63_RS06175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_RS06180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AUC63_RS06185	COG1610	YqeY-like protein
AUC63_RS06190	COG1702	phosphate starvation-inducible protein PhoH
AUC63_RS06195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUC63_RS06200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AUC63_RS06205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUC63_RS06210	COG1381	Involved in DNA repair and RecF pathway recombination
AUC63_RS06220	COG0752	glycyl-tRNA synthetase alpha subunit
AUC63_RS06225	COG0751	glycine-tRNA ligase activity
AUC63_RS06245	COG2706	6-phosphogluconolactonase activity
AUC63_RS06250	COG0628	permease
AUC63_RS06260	COG1674	ftsk spoiiie
AUC63_RS06270	COG4152	abc transporter atp-binding protein
AUC63_RS06275	COG1668	transmembrane transport
AUC63_RS06285	COG0322	excinuclease ABC activity
AUC63_RS06290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUC63_RS06295	COG1739	Uncharacterized protein family UPF0029
AUC63_RS06310	COG0516	GMP reductase activity
AUC63_RS06310	COG0517	IMP dehydrogenase activity
AUC63_RS06315	COG0517	IMP dehydrogenase activity
AUC63_RS06315	COG0516	GMP reductase activity
AUC63_RS06320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AUC63_RS06325	COG0632	four-way junction helicase activity
AUC63_RS06330	COG2255	four-way junction helicase activity
AUC63_RS06335	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AUC63_RS06370	COG0343	queuine tRNA-ribosyltransferase activity
AUC63_RS06375	COG1862	Preprotein translocase
AUC63_RS06380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC63_RS06385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AUC63_RS06390	COG0513	Belongs to the DEAD box helicase family
AUC63_RS06400	COG1929	Belongs to the glycerate kinase type-1 family
AUC63_RS06405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUC63_RS06425	COG3906	Belongs to the UPF0473 family
AUC63_RS06435	COG0658	competence protein
AUC63_RS06435	COG2333	competence protein COMEC
AUC63_RS06440	COG1466	dna polymerase III delta subunit
AUC63_RS06445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUC63_RS06450	COG0268	Binds directly to 16S ribosomal RNA
AUC63_RS06475	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUC63_RS06480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUC63_RS06485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AUC63_RS06505	COG1193	negative regulation of DNA recombination
AUC63_RS06525	COG3118	belongs to the thioredoxin family
AUC63_RS06530	COG0187	DNA topoisomerase II activity
AUC63_RS06535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUC63_RS06540	COG3527	Alpha-acetolactate decarboxylase
AUC63_RS06550	COG1473	amidohydrolase
AUC63_RS06565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_RS06585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AUC63_RS06590	COG3201	nicotinamide mononucleotide transporter
AUC63_RS06635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUC63_RS06640	COG0248	Ppx GppA phosphatase
AUC63_RS06645	COG0604	alcohol dehydrogenase
AUC63_RS06645	COG3321	synthase
AUC63_RS06665	COG2801	Transposase and inactivated derivatives
AUC63_RS06720	COG2801	Transposase and inactivated derivatives
AUC63_RS06750	COG0277	FAD linked oxidase domain protein
AUC63_RS06755	COG0436	Aminotransferase
AUC63_RS06770	COG1464	Belongs to the NlpA lipoprotein family
AUC63_RS06780	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AUC63_RS06785	COG0351	phosphomethylpyrimidine kinase
AUC63_RS06790	COG0352	thiamine-phosphate diphosphorylase activity
AUC63_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_RS06820	COG1940	carbohydrate kinase activity
AUC63_RS06900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUC63_RS06905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC63_RS06920	COG2357	RelA SpoT domain protein
AUC63_RS06925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUC63_RS06930	COG0564	pseudouridine synthase activity
AUC63_RS06935	COG2239	Acts as a magnesium transporter
AUC63_RS06940	COG2814	Major facilitator Superfamily
AUC63_RS06955	COG0488	(ABC) transporter
AUC63_RS06960	COG0488	(ABC) transporter
AUC63_RS06995	COG0583	DNA-binding transcription factor activity
AUC63_RS07005	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS07010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUC63_RS07020	COG1846	Transcriptional regulator
AUC63_RS07075	COG0384	phenazine biosynthesis protein PhzF
AUC63_RS07085	COG1621	beta-fructofuranosidase activity
AUC63_RS07090	COG4684	Psort location CytoplasmicMembrane, score
AUC63_RS07095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC63_RS07100	COG0287	Prephenate dehydrogenase
AUC63_RS07110	COG0738	Major facilitator superfamily
AUC63_RS07115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC63_RS07135	COG1304	FMN binding
AUC63_RS07150	COG0779	Required for maturation of 30S ribosomal subunits
AUC63_RS07155	COG0195	Participates in both transcription termination and antitermination
AUC63_RS07160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AUC63_RS07170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUC63_RS07175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUC63_RS07180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUC63_RS07185	COG1252	NADH dehydrogenase
AUC63_RS07195	COG0196	riboflavin kinase activity
AUC63_RS07200	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AUC63_RS07205	COG3142	Participates in the control of copper homeostasis
AUC63_RS07220	COG2270	Major facilitator Superfamily
AUC63_RS07225	COG1307	EDD domain protein, DegV family
AUC63_RS07230	COG1307	EDD domain protein, DegV family
AUC63_RS07235	COG2755	lipolytic protein G-D-S-L family
AUC63_RS07245	COG4479	Belongs to the UPF0346 family
AUC63_RS07255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUC63_RS07260	COG0758	DNA mediated transformation
AUC63_RS07265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUC63_RS07270	COG4974	Belongs to the 'phage' integrase family
AUC63_RS07280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AUC63_RS07300	COG4175	Glycine betaine
AUC63_RS07300	COG3448	diguanylate cyclase activity
AUC63_RS07310	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_RS07315	COG1464	Belongs to the NlpA lipoprotein family
AUC63_RS07320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC63_RS07325	COG1597	lipid kinase activity
AUC63_RS07330	COG1011	Hydrolase
AUC63_RS07350	COG5503	Protein of unknown function (DUF1447)
AUC63_RS07365	COG0242	peptide deformylase activity
AUC63_RS07370	COG4476	Belongs to the UPF0223 family
AUC63_RS07375	COG0483	inositol monophosphate 1-phosphatase activity
AUC63_RS07380	COG1217	gtp-binding protein TYPA
AUC63_RS07385	COG0772	Belongs to the SEDS family
AUC63_RS07390	COG4471	UPF0298 protein
AUC63_RS07395	COG0742	ribosomal rna small subunit methyltransferase
AUC63_RS07400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUC63_RS07405	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUC63_RS07410	COG0477	Major facilitator Superfamily
AUC63_RS07420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AUC63_RS07425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC63_RS07430	COG0358	DNA primase activity
AUC63_RS07435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUC63_RS07465	COG0745	RESPONSE REGULATOR receiver
AUC63_RS07470	COG5002	protein histidine kinase activity
AUC63_RS07475	COG0572	uridine kinase
AUC63_RS07480	COG1363	Peptidase, m42
AUC63_RS07485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_RS07495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUC63_RS07500	COG0670	Belongs to the BI1 family
AUC63_RS07505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC63_RS07505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC63_RS07510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUC63_RS07515	COG0237	dephospho-CoA kinase activity
AUC63_RS07525	COG1484	DNA-dependent DNA replication
AUC63_RS07540	COG0745	RESPONSE REGULATOR receiver
AUC63_RS07545	COG5002	protein histidine kinase activity
AUC63_RS07555	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_RS07555	COG3942	CHAP domain
AUC63_RS07580	COG0706	membrane insertase activity
AUC63_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_RS07590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_RS07600	COG1304	FMN binding
AUC63_RS07620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AUC63_RS07620	COG1199	ATP-dependent helicase activity
AUC63_RS07630	COG0017	Asparaginyl-tRNA synthetase
AUC63_RS07635	COG3935	DnaD domain protein
AUC63_RS07645	COG3331	DNA recombination
AUC63_RS07650	COG4474	Belongs to the UPF0398 family
AUC63_RS07655	COG3599	regulation of cell shape
AUC63_RS07665	COG0116	Belongs to the methyltransferase superfamily
AUC63_RS07675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUC63_RS07695	COG0556	nucleotide-excision repair
AUC63_RS07705	COG0439	Biotin carboxylase
AUC63_RS07710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC63_RS07720	COG3104	oligopeptide transport
AUC63_RS07725	COG0363	glucosamine-6-phosphate deaminase activity
AUC63_RS07735	COG0537	adenosine 5'-monophosphoramidase activity
AUC63_RS07740	COG1131	(ABC) transporter
AUC63_RS07750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AUC63_RS07755	COG1719	4-vinyl reductase, 4VR
AUC63_RS07760	COG1397	ADP-ribosylglycohydrolase
AUC63_RS07790	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_RS07795	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AUC63_RS07800	COG1349	DNA-binding transcription factor activity
AUC63_RS07805	COG1105	Belongs to the carbohydrate kinase PfkB family
AUC63_RS07810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC63_RS07810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC63_RS07810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC63_RS07820	COG1609	Transcriptional regulator
AUC63_RS07830	COG0306	phosphate transporter
AUC63_RS07840	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUC63_RS07850	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS07870	COG0531	amino acid
AUC63_RS07880	COG0481	GTPase activity
AUC63_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_RS07915	COG4708	membrane
AUC63_RS07925	COG0531	amino acid
AUC63_RS07930	COG4221	oxidoreductase activity
AUC63_RS07935	COG0583	DNA-binding transcription factor activity
AUC63_RS07940	COG0281	malic enzyme
AUC63_RS07950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC63_RS07965	COG1136	(ABC) transporter
AUC63_RS07970	COG0577	efflux transmembrane transporter activity
AUC63_RS07980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AUC63_RS07990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUC63_RS07995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUC63_RS08025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUC63_RS08030	COG2384	SAM-dependent methyltransferase
AUC63_RS08035	COG0071	Belongs to the small heat shock protein (HSP20) family
AUC63_RS08040	COG0457	Tetratricopeptide repeat
AUC63_RS08075	COG0419	ATPase involved in DNA repair
AUC63_RS08080	COG0420	3'-5' exonuclease activity
AUC63_RS08090	COG2807	transmembrane transport
AUC63_RS08095	COG4720	Psort location CytoplasmicMembrane, score
AUC63_RS08100	COG0351	phosphomethylpyrimidine kinase
AUC63_RS08110	COG1160	GTP binding
AUC63_RS08115	COG0539	negative regulation of cytoplasmic translation
AUC63_RS08120	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUC63_RS08130	COG0514	ATP-dependent DNA helicase (RecQ)
AUC63_RS08140	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AUC63_RS08155	COG1187	pseudouridine synthase activity
AUC63_RS08160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUC63_RS08165	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AUC63_RS08180	COG2996	Protein conserved in bacteria
AUC63_RS08190	COG0475	glutathione-regulated potassium exporter activity
AUC63_RS08200	COG1490	D-aminoacyl-tRNA deacylase activity
AUC63_RS08205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUC63_RS08210	COG0587	DNA-directed DNA polymerase activity
AUC63_RS08220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUC63_RS08225	COG0488	(ABC) transporter
AUC63_RS08230	COG0617	tRNA 3'-terminal CCA addition
AUC63_RS08250	COG1266	CAAX protease self-immunity
AUC63_RS08255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUC63_RS08260	COG0004	ammonium transporteR
AUC63_RS08270	COG0366	Alpha amylase catalytic
AUC63_RS08270	COG5263	repeat protein
AUC63_RS08275	COG1316	TRANSCRIPTIONal
AUC63_RS08280	COG1216	Glycosyl transferase, family 2
AUC63_RS08295	COG1216	Glycosyl transferase, family 2
AUC63_RS08305	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS08310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC63_RS08315	COG0489	protein tyrosine kinase activity
AUC63_RS08330	COG0233	cytoplasmic translational termination
AUC63_RS08340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUC63_RS08345	COG0052	Belongs to the universal ribosomal protein uS2 family
AUC63_RS08350	COG2827	Endonuclease containing a URI domain
AUC63_RS08355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AUC63_RS08360	COG0204	Acyl-transferase
AUC63_RS08365	COG0791	NLP P60 protein
AUC63_RS08365	COG3883	PFAM NLP P60 protein
AUC63_RS08380	COG3763	UPF0154 protein
AUC63_RS08385	COG4224	UPF0291 protein
AUC63_RS08390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUC63_RS08410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AUC63_RS08410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AUC63_RS08415	COG1234	tRNA 3'-trailer cleavage
AUC63_RS08430	COG0484	heat shock protein binding
AUC63_RS08435	COG0443	Heat shock 70 kDa protein
AUC63_RS08445	COG1420	regulation of RNA biosynthetic process
AUC63_RS08475	COG1216	Glycosyl transferase, family 2
AUC63_RS08485	COG0463	Glycosyl transferase, family 2
AUC63_RS08495	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_RS08510	COG0562	UDP-galactopyranose mutase
AUC63_RS08535	COG0024	Methionine aminopeptidase
AUC63_RS08565	COG2801	Transposase and inactivated derivatives
AUC63_RS08600	COG2309	aminopeptidase activity
AUC63_RS08615	COG0564	pseudouridine synthase activity
AUC63_RS08620	COG1278	Cold shock
AUC63_RS08630	COG2814	Major facilitator Superfamily
AUC63_RS08635	COG0741	lytic transglycosylase activity
AUC63_RS08645	COG3973	AAA domain
AUC63_RS08655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUC63_RS08660	COG1058	Belongs to the CinA family
AUC63_RS08660	COG1546	Belongs to the CinA family
AUC63_RS08665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AUC63_RS08670	COG1426	Protein conserved in bacteria
AUC63_RS08675	COG0612	Peptidase, M16
AUC63_RS08680	COG0612	Peptidase, M16
AUC63_RS08695	COG0028	Belongs to the TPP enzyme family
AUC63_RS08715	COG4717	serine-type aminopeptidase activity
AUC63_RS08730	COG3679	Belongs to the UPF0342 family
AUC63_RS08735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUC63_RS08740	COG1438	arginine binding
AUC63_RS08770	COG1959	2 iron, 2 sulfur cluster binding
AUC63_RS08795	COG0018	arginyl-trna synthetase
AUC63_RS08810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC63_RS08820	COG1121	(ABC) transporter
AUC63_RS08840	COG1597	lipid kinase activity
AUC63_RS08845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC63_RS08850	COG0154	amidase activity
AUC63_RS08855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC63_RS08860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC63_RS08860	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AUC63_RS08870	COG2936	dipeptidyl-peptidase activity
AUC63_RS08885	COG1695	Transcriptional regulator
AUC63_RS08895	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC63_RS08915	COG0667	Aldo Keto reductase
AUC63_RS08920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC63_RS08925	COG4721	ABC-type cobalt transport system, permease component
AUC63_RS08930	COG1122	ATPase activity
AUC63_RS08945	COG0758	DNA mediated transformation
AUC63_RS08960	COG0710	3-dehydroquinate dehydratase activity
AUC63_RS08965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AUC63_RS08970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC63_RS08975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC63_RS08980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUC63_RS08985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AUC63_RS08990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUC63_RS09005	COG4684	Psort location CytoplasmicMembrane, score
AUC63_RS09010	COG0436	Aminotransferase
AUC63_RS09030	COG2801	Transposase and inactivated derivatives
AUC63_RS09045	COG1783	phage Terminase large subunit
AUC63_RS09190	COG1396	sequence-specific DNA binding
AUC63_RS09225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUC63_RS09230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AUC63_RS09235	COG0436	Aminotransferase
AUC63_RS09240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUC63_RS09245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUC63_RS09255	COG2171	N-acyltransferase activity
AUC63_RS09265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUC63_RS09270	COG0527	aspartate kinase activity
AUC63_RS09280	COG1609	Transcriptional regulator
AUC63_RS09285	COG0083	homoserine kinase activity
AUC63_RS09300	COG1321	iron dependent repressor
AUC63_RS09305	COG3764	Sortase (surface protein transpeptidase)
AUC63_RS09325	COG0513	Belongs to the DEAD box helicase family
AUC63_RS09330	COG0673	inositol 2-dehydrogenase activity
AUC63_RS09335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_RS09345	COG0501	Belongs to the peptidase M48B family
AUC63_RS09350	COG1704	LemA family
AUC63_RS09360	COG4115	mRNA cleavage
AUC63_RS09365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC63_RS09380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC63_RS09390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC63_RS09395	COG0439	Biotin carboxylase
AUC63_RS09410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AUC63_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_RS09420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AUC63_RS09425	COG2070	2-Nitropropane dioxygenase
AUC63_RS09430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC63_RS09435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC63_RS09440	COG1846	Transcriptional regulator
AUC63_RS09445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AUC63_RS09455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUC63_RS09460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AUC63_RS09470	COG0505	Belongs to the CarA family
AUC63_RS09480	COG0564	pseudouridine synthase activity
AUC63_RS09490	COG0328	RNA-DNA hybrid ribonuclease activity
AUC63_RS09495	COG1757	Na H antiporter
AUC63_RS09500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AUC63_RS09505	COG1113	amino acid transport
AUC63_RS09530	COG0656	L-ascorbic acid biosynthetic process
AUC63_RS09540	COG1454	alcohol dehydrogenase
AUC63_RS09540	COG1012	belongs to the aldehyde dehydrogenase family
AUC63_RS09545	COG0105	UTP biosynthetic process
AUC63_RS09555	COG0583	DNA-binding transcription factor activity
AUC63_RS09560	COG0126	phosphoglycerate kinase activity
AUC63_RS09610	COG0588	phosphoglycerate mutase activity
AUC63_RS09620	COG3716	PTS system mannose fructose sorbose family IID component
AUC63_RS09625	COG3715	PTS system
AUC63_RS09640	COG1397	ADP-ribosylglycohydrolase
AUC63_RS09700	COG1368	sulfuric ester hydrolase activity
AUC63_RS09715	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS09720	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS09725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUC63_RS09730	COG0284	orotidine-5'-phosphate decarboxylase activity
AUC63_RS09735	COG0167	dihydroorotate dehydrogenase activity
AUC63_RS09740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC63_RS09745	COG0505	Belongs to the CarA family
AUC63_RS09750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUC63_RS09755	COG0540	Belongs to the ATCase OTCase family
AUC63_RS09775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC63_RS09780	COG4856	YbbR-like protein
AUC63_RS09795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUC63_RS09810	COG0802	atpase or kinase
AUC63_RS09815	COG0280	phosphate acetyltransferase
AUC63_RS09820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUC63_RS09830	COG2076	Multidrug Resistance protein
AUC63_RS09835	COG2076	Multidrug Resistance protein
AUC63_RS09840	COG1126	abc transporter atp-binding protein
AUC63_RS09845	COG0765	amino acid transport
AUC63_RS09850	COG2814	Major facilitator Superfamily
AUC63_RS09865	COG0557	exoribonuclease II activity
AUC63_RS09875	COG2814	Major facilitator Superfamily
AUC63_RS09880	COG0154	amidase activity
AUC63_RS09900	COG0149	triose-phosphate isomerase activity
AUC63_RS09905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUC63_RS09910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC63_RS09920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC63_RS09925	COG0492	ferredoxin-NADP+ reductase activity
AUC63_RS09950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AUC63_RS09955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUC63_RS09960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AUC63_RS09965	COG1950	PFAM Membrane protein of
AUC63_RS09975	COG0589	response to stress
AUC63_RS09985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC63_RS09995	COG1177	transmembrane transport
AUC63_RS10005	COG3842	ATPase activity
AUC63_RS10015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUC63_RS10020	COG0049	tRNA binding
AUC63_RS10025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUC63_RS10040	COG4608	Belongs to the ABC transporter superfamily
AUC63_RS10045	COG0444	Belongs to the ABC transporter superfamily
AUC63_RS10050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_RS10055	COG0601	transmembrane transport
AUC63_RS10065	COG0460	homoserine dehydrogenase
AUC63_RS10070	COG0626	cystathionine gamma-synthase activity
AUC63_RS10075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AUC63_RS10085	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_RS10090	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUC63_RS10095	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUC63_RS10110	COG1302	Protein conserved in bacteria
AUC63_RS10115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUC63_RS10125	COG2017	converts alpha-aldose to the beta-anomer
AUC63_RS10135	COG4975	Glucose uptake
AUC63_RS10140	COG5002	protein histidine kinase activity
AUC63_RS10140	COG3850	Histidine kinase
AUC63_RS10145	COG0745	RESPONSE REGULATOR receiver
AUC63_RS10150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_RS10155	COG0402	S-adenosylhomocysteine deaminase activity
AUC63_RS10160	COG0673	inositol 2-dehydrogenase activity
AUC63_RS10165	COG0741	lytic transglycosylase activity
AUC63_RS10185	COG0668	transmembrane transport
AUC63_RS10195	COG1126	abc transporter atp-binding protein
AUC63_RS10230	COG0516	GMP reductase activity
AUC63_RS10300	COG2801	Transposase and inactivated derivatives
AUC63_RS10315	COG0494	nUDIX hydrolase
AUC63_RS10355	COG0738	Major facilitator superfamily
AUC63_RS10360	COG1869	D-ribose catabolic process
AUC63_RS10365	COG1609	Transcriptional regulator
AUC63_RS10385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC63_RS10400	COG1609	Transcriptional regulator
AUC63_RS10420	COG2223	nitrite transmembrane transporter activity
AUC63_RS10430	COG0318	PFAM AMP-dependent synthetase and ligase
AUC63_RS10440	COG1116	anion transmembrane transporter activity
AUC63_RS10445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUC63_RS10455	COG0285	dihydrofolate synthase activity
AUC63_RS10460	COG0302	gtp cyclohydrolase
AUC63_RS10465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AUC63_RS10465	COG0302	gtp cyclohydrolase
AUC63_RS10505	COG0561	phosphatase activity
AUC63_RS10520	COG4946	Tricorn protease homolog
AUC63_RS10520	COG0823	Involved in the tonB-independent uptake of proteins
AUC63_RS10520	COG1506	peptidase
AUC63_RS10525	COG1464	Belongs to the NlpA lipoprotein family
AUC63_RS10530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC63_RS10535	COG0800	Aldolase
AUC63_RS10540	COG1904	glucuronate isomerase
AUC63_RS10545	COG1312	Catalyzes the dehydration of D-mannonate
AUC63_RS10550	COG0246	Mannitol dehydrogenase
AUC63_RS10565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUC63_RS10580	COG1609	Transcriptional regulator
AUC63_RS10610	COG0577	efflux transmembrane transporter activity
AUC63_RS10615	COG1136	(ABC) transporter
AUC63_RS10620	COG3759	membrane
AUC63_RS10645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC63_RS10650	COG2235	arginine
AUC63_RS10660	COG2217	Heavy metal translocating P-type atpase
AUC63_RS10710	COG0438	transferase activity, transferring glycosyl groups
AUC63_RS10750	COG2814	Major facilitator Superfamily
AUC63_RS10755	COG2217	Heavy metal translocating P-type atpase
AUC63_RS10775	COG1309	transcriptional regulator
AUC63_RS10795	COG3711	transcriptional antiterminator
AUC63_RS10800	COG2723	6-phospho-beta-galactosidase activity
AUC63_RS10805	COG1940	carbohydrate kinase activity
AUC63_RS10830	COG2183	response to ionizing radiation
AUC63_RS10840	COG2873	o-acetylhomoserine
AUC63_RS10845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AUC63_RS10850	COG1040	competence protein
AUC63_RS10855	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)