locus-tag	class	description
AUC65_RS00040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AUC65_RS00060	COG1368	sulfuric ester hydrolase activity
AUC65_RS00065	COG2153	protein acetylation
AUC65_RS00080	COG0187	DNA topoisomerase II activity
AUC65_RS00085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUC65_RS00090	COG2501	S4 domain
AUC65_RS00095	COG0592	DNA-directed DNA polymerase activity
AUC65_RS00100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUC65_RS00105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AUC65_RS00110	COG0594	ribonuclease P activity
AUC65_RS00115	COG0706	membrane insertase activity
AUC65_RS00125	COG1120	ATPase activity
AUC65_RS00135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AUC65_RS00150	COG0569	domain protein
AUC65_RS00155	COG1113	amino acid transport
AUC65_RS00175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC65_RS00185	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_RS00195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AUC65_RS00200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUC65_RS00210	COG1136	(ABC) transporter
AUC65_RS00215	COG0577	efflux transmembrane transporter activity
AUC65_RS00220	COG2409	Drug exporters of the RND superfamily
AUC65_RS00220	COG1033	growth of symbiont in host cell
AUC65_RS00225	COG0561	phosphatase activity
AUC65_RS00235	COG0328	RNA-DNA hybrid ribonuclease activity
AUC65_RS00255	COG3152	Membrane
AUC65_RS00260	COG2252	PERMEase
AUC65_RS00300	COG1881	PFAM PEBP family protein
AUC65_RS00370	COG1476	TRANSCRIPTIONal
AUC65_RS00395	COG0517	IMP dehydrogenase activity
AUC65_RS00395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC65_RS00400	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS00420	COG0697	spore germination
AUC65_RS00435	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS00440	COG0137	argininosuccinate synthase activity
AUC65_RS00445	COG0165	Argininosuccinate lyase
AUC65_RS00450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUC65_RS00455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUC65_RS00465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AUC65_RS00470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC65_RS00475	COG0505	Belongs to the CarA family
AUC65_RS00480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC65_RS00500	COG1131	(ABC) transporter
AUC65_RS00520	COG0789	Transcriptional regulator
AUC65_RS00535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_RS00545	COG0697	spore germination
AUC65_RS00550	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS00570	COG1846	Transcriptional regulator
AUC65_RS00575	COG1132	(ABC) transporter
AUC65_RS00585	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS00595	COG4619	ABC transporter
AUC65_RS00600	COG0390	transport system, permease component
AUC65_RS00610	COG1131	(ABC) transporter
AUC65_RS00620	COG1126	abc transporter atp-binding protein
AUC65_RS00625	COG0765	amino acid transport
AUC65_RS00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_RS00640	COG1254	Belongs to the acylphosphatase family
AUC65_RS00650	COG0392	lysyltransferase activity
AUC65_RS00650	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUC65_RS00660	COG0628	permease
AUC65_RS00690	COG1113	amino acid transport
AUC65_RS00715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AUC65_RS00730	COG2855	membrane
AUC65_RS00735	COG3620	sequence-specific DNA binding
AUC65_RS00745	COG2855	membrane
AUC65_RS00750	COG0583	DNA-binding transcription factor activity
AUC65_RS00760	COG2070	2-Nitropropane dioxygenase
AUC65_RS00775	COG1228	amidohydrolase
AUC65_RS00780	COG0531	amino acid
AUC65_RS00790	COG3223	Belongs to the PsiE family
AUC65_RS00800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC65_RS00810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AUC65_RS00820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC65_RS00825	COG4166	transmembrane transport
AUC65_RS00830	COG2267	carboxylic ester hydrolase activity
AUC65_RS00835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AUC65_RS00845	COG0477	Major facilitator Superfamily
AUC65_RS00850	COG4975	Glucose uptake
AUC65_RS00860	COG0531	amino acid
AUC65_RS00865	COG1113	amino acid transport
AUC65_RS00870	COG0531	amino acid
AUC65_RS00875	COG0252	asparaginase activity
AUC65_RS00880	COG4443	Transcriptional Coactivator p15 (PC4)
AUC65_RS00890	COG2226	methyltransferase
AUC65_RS00895	COG1335	isochorismatase
AUC65_RS00900	COG2050	protein possibly involved in aromatic compounds catabolism
AUC65_RS00905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUC65_RS00910	COG0318	PFAM AMP-dependent synthetase and ligase
AUC65_RS00925	COG0745	RESPONSE REGULATOR receiver
AUC65_RS00930	COG5002	protein histidine kinase activity
AUC65_RS00970	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC65_RS00975	COG1194	a g-specific adenine glycosylase
AUC65_RS00985	COG0357	Ribosomal RNA small subunit methyltransferase G
AUC65_RS00990	COG1192	Involved in chromosome partitioning
AUC65_RS00995	COG1475	DNA binding
AUC65_RS01000	COG4481	Protein conserved in bacteria
AUC65_RS01005	COG0012	GTP binding
AUC65_RS01015	COG0745	RESPONSE REGULATOR receiver
AUC65_RS01025	COG1686	Belongs to the peptidase S11 family
AUC65_RS01075	COG3104	oligopeptide transport
AUC65_RS01080	COG0477	Major facilitator Superfamily
AUC65_RS01085	COG4975	Glucose uptake
AUC65_RS01130	COG3091	SprT-like family
AUC65_RS01135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AUC65_RS01135	COG2755	lipolytic protein G-D-S-L family
AUC65_RS01150	COG1846	Transcriptional regulator
AUC65_RS01160	COG1121	(ABC) transporter
AUC65_RS01165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC65_RS01170	COG1373	ATPase (AAA superfamily
AUC65_RS01175	COG0488	(ABC) transporter
AUC65_RS01180	COG0534	Mate efflux family protein
AUC65_RS01195	COG3940	Belongs to the glycosyl hydrolase 43 family
AUC65_RS01220	COG2160	L-arabinose isomerase activity
AUC65_RS01225	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS01260	COG0765	amino acid transport
AUC65_RS01290	COG1215	transferase activity, transferring glycosyl groups
AUC65_RS01295	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AUC65_RS01300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AUC65_RS01315	COG1418	mRNA catabolic process
AUC65_RS01320	COG2814	Major facilitator Superfamily
AUC65_RS01325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC65_RS01330	COG2188	Transcriptional regulator
AUC65_RS01335	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AUC65_RS01350	COG0463	Glycosyl transferase, family 2
AUC65_RS01350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AUC65_RS01370	COG1442	glycosyl transferase family 8
AUC65_RS01370	COG1216	Glycosyl transferase, family 2
AUC65_RS01375	COG1215	transferase activity, transferring glycosyl groups
AUC65_RS01380	COG2801	Transposase and inactivated derivatives
AUC65_RS01395	COG5039	Polysaccharide pyruvyl transferase
AUC65_RS01435	COG3590	peptidase
AUC65_RS01440	COG1012	belongs to the aldehyde dehydrogenase family
AUC65_RS01440	COG1454	alcohol dehydrogenase
AUC65_RS01450	COG0708	Exodeoxyribonuclease III
AUC65_RS01470	COG0588	phosphoglycerate mutase activity
AUC65_RS01475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AUC65_RS01490	COG1132	(ABC) transporter
AUC65_RS01495	COG1132	(ABC) transporter
AUC65_RS01520	COG0110	maltose O-acetyltransferase activity
AUC65_RS01530	COG1482	cell wall glycoprotein biosynthetic process
AUC65_RS01535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC65_RS01540	COG3442	glutamine amidotransferase
AUC65_RS01550	COG1435	thymidine kinase activity
AUC65_RS01555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUC65_RS01560	COG2890	protein-(glutamine-N5) methyltransferase activity
AUC65_RS01565	COG0009	L-threonylcarbamoyladenylate synthase
AUC65_RS01570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUC65_RS01575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AUC65_RS01580	COG0702	epimerase
AUC65_RS01590	COG2233	PERMEase
AUC65_RS01595	COG0356	it plays a direct role in the translocation of protons across the membrane
AUC65_RS01600	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC65_RS01605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUC65_RS01610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC65_RS01615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUC65_RS01620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUC65_RS01625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUC65_RS01630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUC65_RS01635	COG1876	peptidase activity
AUC65_RS01640	COG1428	Deoxynucleoside kinase
AUC65_RS01645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUC65_RS01670	COG4463	regulation of RNA biosynthetic process
AUC65_RS01675	COG0542	response to heat
AUC65_RS01680	COG0085	RNA polymerase activity
AUC65_RS01695	COG1979	alcohol dehydrogenase
AUC65_RS01710	COG1309	transcriptional regulator
AUC65_RS01715	COG0500	methyltransferase
AUC65_RS01760	COG3620	sequence-specific DNA binding
AUC65_RS01770	COG2807	transmembrane transport
AUC65_RS01780	COG2813	Specifically methylates the guanine in position
AUC65_RS01785	COG0590	tRNA wobble adenosine to inosine editing
AUC65_RS01795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AUC65_RS01820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUC65_RS01825	COG3870	Protein conserved in bacteria
AUC65_RS01845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUC65_RS01850	COG1214	PFAM Peptidase M22, glycoprotease
AUC65_RS01855	COG0456	acetyltransferase
AUC65_RS01865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUC65_RS01870	COG0142	geranyltranstransferase activity
AUC65_RS01875	COG0051	transcription antitermination factor activity, RNA binding
AUC65_RS01880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUC65_RS01890	COG0089	rRNA binding
AUC65_RS01895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUC65_RS01900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUC65_RS01905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUC65_RS01910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUC65_RS01915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUC65_RS01920	COG0255	Belongs to the universal ribosomal protein uL29 family
AUC65_RS01930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUC65_RS01935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUC65_RS01940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUC65_RS01945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUC65_RS01950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUC65_RS01955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AUC65_RS01960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUC65_RS01965	COG1841	ribosomal large subunit assembly
AUC65_RS01970	COG0200	Binds to the 23S rRNA
AUC65_RS01985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUC65_RS01990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUC65_RS01995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AUC65_RS02000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUC65_RS02005	COG0202	RNA polymerase activity
AUC65_RS02010	COG0203	ribosomal protein L17
AUC65_RS02035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AUC65_RS02050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AUC65_RS02075	COG0583	DNA-binding transcription factor activity
AUC65_RS02080	COG0114	fumarate hydratase activity
AUC65_RS02085	COG1053	succinate dehydrogenase
AUC65_RS02090	COG0471	metal ion transport
AUC65_RS02095	COG0039	L-malate dehydrogenase activity
AUC65_RS02100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUC65_RS02105	COG0215	cysteine-tRNA ligase activity
AUC65_RS02110	COG0626	cystathionine gamma-synthase activity
AUC65_RS02115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AUC65_RS02120	COG1464	Belongs to the NlpA lipoprotein family
AUC65_RS02125	COG1854	S-ribosylhomocysteine lyase activity
AUC65_RS02130	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AUC65_RS02135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC65_RS02150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUC65_RS02155	COG0250	Participates in transcription elongation, termination and antitermination
AUC65_RS02160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUC65_RS02165	COG0081	regulation of translation
AUC65_RS02170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUC65_RS02175	COG0222	ribosome binding
AUC65_RS02185	COG1121	(ABC) transporter
AUC65_RS02190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC65_RS02195	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUC65_RS02200	COG1252	NADH dehydrogenase
AUC65_RS02210	COG1122	ATPase activity
AUC65_RS02215	COG1122	ATPase activity
AUC65_RS02225	COG0101	tRNA pseudouridine synthase activity
AUC65_RS02230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUC65_RS02240	COG4221	oxidoreductase activity
AUC65_RS02260	COG0028	Belongs to the TPP enzyme family
AUC65_RS02270	COG1573	uracil-dna glycosylase
AUC65_RS02285	COG0366	Alpha amylase catalytic
AUC65_RS02295	COG0671	phosphoesterase, PA-phosphatase related
AUC65_RS02305	COG2814	Major facilitator Superfamily
AUC65_RS02310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC65_RS02320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AUC65_RS02325	COG1481	regulation of sporulation
AUC65_RS02330	COG0740	serine-type endopeptidase activity
AUC65_RS02345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_RS02345	COG1263	PTS System
AUC65_RS02355	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC65_RS02375	COG0039	L-malate dehydrogenase activity
AUC65_RS02380	COG0028	Belongs to the TPP enzyme family
AUC65_RS02385	COG3527	Alpha-acetolactate decarboxylase
AUC65_RS02395	COG3942	CHAP domain
AUC65_RS02395	COG1388	LysM domain
AUC65_RS02400	COG0791	NLP P60 protein
AUC65_RS02410	COG0756	dUTP diphosphatase activity
AUC65_RS02420	COG4956	integral membrane protein (PIN domain superfamily)
AUC65_RS02430	COG0653	protein targeting
AUC65_RS02435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUC65_RS02455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC65_RS02465	COG1733	regulation of RNA biosynthetic process
AUC65_RS02470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUC65_RS02475	COG0072	phenylalanine-tRNA ligase activity
AUC65_RS02475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_RS02480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AUC65_RS02485	COG0514	ATP-dependent DNA helicase (RecQ)
AUC65_RS02490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUC65_RS02500	COG0768	penicillin binding
AUC65_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AUC65_RS02520	COG1940	carbohydrate kinase activity
AUC65_RS02525	COG3409	Peptidoglycan-binding domain 1 protein
AUC65_RS02525	COG5632	N-Acetylmuramoyl-L-alanine amidase
AUC65_RS02530	COG3942	CHAP domain
AUC65_RS02550	COG0584	glycerophosphoryl diester phosphodiesterase
AUC65_RS02555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUC65_RS02560	COG0789	Transcriptional regulator
AUC65_RS02565	COG0174	glutamine synthetase
AUC65_RS02590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUC65_RS02595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUC65_RS02600	COG1472	Belongs to the glycosyl hydrolase 3 family
AUC65_RS02610	COG1132	(ABC) transporter
AUC65_RS02615	COG0778	Nitroreductase
AUC65_RS02620	COG1169	isochorismate synthase
AUC65_RS02625	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUC65_RS02630	COG0596	Alpha beta hydrolase
AUC65_RS02635	COG4948	Mandelate Racemase Muconate Lactonizing
AUC65_RS02655	COG0737	Belongs to the 5'-nucleotidase family
AUC65_RS02660	COG4470	Protein conserved in bacteria
AUC65_RS02665	COG0647	UMP catabolic process
AUC65_RS02670	COG4166	transmembrane transport
AUC65_RS02675	COG0673	inositol 2-dehydrogenase activity
AUC65_RS02700	COG0573	inorganic phosphate transmembrane transporter activity
AUC65_RS02705	COG0581	inorganic phosphate transmembrane transporter activity
AUC65_RS02710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC65_RS02715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC65_RS02720	COG0704	Plays a role in the regulation of phosphate uptake
AUC65_RS02725	COG2137	regulation of response to DNA damage stimulus
AUC65_RS02750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AUC65_RS02760	COG5506	Protein of unknown function (DUF1694)
AUC65_RS02770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AUC65_RS02880	COG1272	protein, Hemolysin III
AUC65_RS02915	COG0525	valine-tRNA ligase activity
AUC65_RS02925	COG0285	dihydrofolate synthase activity
AUC65_RS02945	COG0488	(ABC) transporter
AUC65_RS02950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUC65_RS02955	COG0459	protein refolding
AUC65_RS02960	COG0531	amino acid
AUC65_RS02970	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUC65_RS02975	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AUC65_RS02980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AUC65_RS02990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUC65_RS02995	COG1713	HD superfamily hydrolase involved in NAD metabolism
AUC65_RS03000	COG0799	negative regulation of ribosome biogenesis
AUC65_RS03005	COG2226	methyltransferase
AUC65_RS03010	COG1323	Belongs to the UPF0348 family
AUC65_RS03020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AUC65_RS03025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AUC65_RS03115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUC65_RS03125	COG0363	glucosamine-6-phosphate deaminase activity
AUC65_RS03130	COG0776	regulation of translation
AUC65_RS03140	COG0577	efflux transmembrane transporter activity
AUC65_RS03145	COG1136	(ABC) transporter
AUC65_RS03160	COG4720	Psort location CytoplasmicMembrane, score
AUC65_RS03165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUC65_RS03170	COG1570	exodeoxyribonuclease VII activity
AUC65_RS03180	COG0142	geranyltranstransferase activity
AUC65_RS03185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AUC65_RS03190	COG1438	arginine binding
AUC65_RS03195	COG0497	DNA recombination
AUC65_RS03205	COG0194	GDP metabolic process
AUC65_RS03215	COG0586	Pfam SNARE associated Golgi protein
AUC65_RS03220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC65_RS03225	COG1098	S1 RNA binding domain
AUC65_RS03340	COG4684	Psort location CytoplasmicMembrane, score
AUC65_RS03345	COG1271	oxidase subunit
AUC65_RS03350	COG1294	oxidase, subunit
AUC65_RS03355	COG4988	ABC transporter
AUC65_RS03360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AUC65_RS03365	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_RS03365	COG1388	LysM domain
AUC65_RS03370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AUC65_RS03385	COG1278	Cold shock
AUC65_RS03390	COG0494	nUDIX hydrolase
AUC65_RS03400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AUC65_RS03405	COG0346	lactoylglutathione lyase activity
AUC65_RS03410	COG0400	carboxylic ester hydrolase activity
AUC65_RS03420	COG0741	lytic transglycosylase activity
AUC65_RS03440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AUC65_RS03445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC65_RS03450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC65_RS03460	COG4120	Belongs to the binding-protein-dependent transport system permease family
AUC65_RS03470	COG0038	chloride channel
AUC65_RS03475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC65_RS03480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC65_RS03485	COG1307	EDD domain protein, DegV family
AUC65_RS03490	COG2190	(PTS) system
AUC65_RS03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_RS03490	COG1263	PTS System
AUC65_RS03505	COG2003	Belongs to the UPF0758 family
AUC65_RS03510	COG1077	Cell shape determining protein MreB Mrl
AUC65_RS03520	COG3338	carbonate dehydratase activity
AUC65_RS03530	COG0765	amino acid transport
AUC65_RS03535	COG1126	abc transporter atp-binding protein
AUC65_RS03540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_RS03545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_RS03545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_RS03550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AUC65_RS03555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AUC65_RS03560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUC65_RS03575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUC65_RS03585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUC65_RS03590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AUC65_RS03595	COG0138	bifunctional purine biosynthesis protein purh
AUC65_RS03600	COG0151	Belongs to the GarS family
AUC65_RS03605	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AUC65_RS03620	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_RS03635	COG0833	amino acid
AUC65_RS03645	COG2264	protein methyltransferase activity
AUC65_RS03650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AUC65_RS03660	COG2001	Belongs to the MraZ family
AUC65_RS03665	COG0275	rRNA processing
AUC65_RS03675	COG0768	penicillin binding
AUC65_RS03680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUC65_RS03685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUC65_RS03690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUC65_RS03695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AUC65_RS03700	COG0849	cell division
AUC65_RS03710	COG1799	cell septum assembly
AUC65_RS03725	COG3599	regulation of cell shape
AUC65_RS03745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_RS03750	COG0217	transcriptional regulatory protein
AUC65_RS03755	COG2252	PERMEase
AUC65_RS03760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AUC65_RS03800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC65_RS03805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AUC65_RS03810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUC65_RS03815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC65_RS03815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUC65_RS03820	COG0631	protein serine/threonine phosphatase activity
AUC65_RS03825	COG0515	serine threonine protein kinase
AUC65_RS03825	COG2815	serine threonine protein kinase
AUC65_RS03830	COG1162	GTPase activity
AUC65_RS03835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUC65_RS03845	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUC65_RS03855	COG1461	Dihydroxyacetone kinase
AUC65_RS03870	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS03880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AUC65_RS03885	COG0416	fatty acid biosynthetic process
AUC65_RS03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC65_RS03895	COG0571	ribonuclease III activity
AUC65_RS03900	COG1196	nuclear chromosome segregation
AUC65_RS03905	COG0552	protein localization to endoplasmic reticulum
AUC65_RS03910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AUC65_RS03915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AUC65_RS03930	COG0228	four-way junction DNA binding
AUC65_RS03945	COG0588	phosphoglycerate mutase activity
AUC65_RS03950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUC65_RS03955	COG0336	Belongs to the RNA methyltransferase TrmD family
AUC65_RS03960	COG0335	large ribosomal subunit rRNA binding
AUC65_RS03970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_RS03975	COG1942	4-Oxalocrotonate Tautomerase
AUC65_RS03980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUC65_RS03990	COG1428	Deoxynucleoside kinase
AUC65_RS03995	COG1970	mechanosensitive ion channel activity
AUC65_RS04000	COG0561	phosphatase activity
AUC65_RS04065	COG3853	Toxic anion resistance protein (TelA)
AUC65_RS04070	COG1393	Belongs to the ArsC family
AUC65_RS04075	COG4862	establishment of competence for transformation
AUC65_RS04080	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS04085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_RS04090	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC65_RS04095	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS04100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_RS04110	COG1164	Oligoendopeptidase f
AUC65_RS04115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC65_RS04130	COG1609	Transcriptional regulator
AUC65_RS04135	COG0006	proline dipeptidase activity
AUC65_RS04205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AUC65_RS04210	COG3425	synthase
AUC65_RS04225	COG0860	N-Acetylmuramoyl-L-alanine amidase
AUC65_RS04230	COG0124	histidyl-tRNA synthetase
AUC65_RS04235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AUC65_RS04245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_RS04250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AUC65_RS04255	COG1610	YqeY-like protein
AUC65_RS04260	COG1702	phosphate starvation-inducible protein PhoH
AUC65_RS04265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUC65_RS04270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AUC65_RS04275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUC65_RS04280	COG1381	Involved in DNA repair and RecF pathway recombination
AUC65_RS04290	COG0752	glycyl-tRNA synthetase alpha subunit
AUC65_RS04295	COG0751	glycine-tRNA ligase activity
AUC65_RS04315	COG2706	6-phosphogluconolactonase activity
AUC65_RS04320	COG0628	permease
AUC65_RS04330	COG1674	ftsk spoiiie
AUC65_RS04340	COG4152	abc transporter atp-binding protein
AUC65_RS04345	COG1668	transmembrane transport
AUC65_RS04355	COG0322	excinuclease ABC activity
AUC65_RS04360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUC65_RS04365	COG1739	Uncharacterized protein family UPF0029
AUC65_RS04380	COG0517	IMP dehydrogenase activity
AUC65_RS04380	COG0516	GMP reductase activity
AUC65_RS04385	COG0517	IMP dehydrogenase activity
AUC65_RS04385	COG0516	GMP reductase activity
AUC65_RS04390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AUC65_RS04395	COG0632	four-way junction helicase activity
AUC65_RS04400	COG2255	four-way junction helicase activity
AUC65_RS04405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AUC65_RS04440	COG0343	queuine tRNA-ribosyltransferase activity
AUC65_RS04445	COG1862	Preprotein translocase
AUC65_RS04450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC65_RS04455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AUC65_RS04460	COG0513	Belongs to the DEAD box helicase family
AUC65_RS04470	COG1929	Belongs to the glycerate kinase type-1 family
AUC65_RS04475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUC65_RS04495	COG3906	Belongs to the UPF0473 family
AUC65_RS04505	COG0658	competence protein
AUC65_RS04505	COG2333	competence protein COMEC
AUC65_RS04510	COG1466	dna polymerase III delta subunit
AUC65_RS04515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUC65_RS04520	COG0268	Binds directly to 16S ribosomal RNA
AUC65_RS04545	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUC65_RS04550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUC65_RS04555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AUC65_RS04575	COG1193	negative regulation of DNA recombination
AUC65_RS04595	COG3118	belongs to the thioredoxin family
AUC65_RS04600	COG0187	DNA topoisomerase II activity
AUC65_RS04605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUC65_RS04610	COG3527	Alpha-acetolactate decarboxylase
AUC65_RS04620	COG1473	amidohydrolase
AUC65_RS04635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_RS04655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AUC65_RS04660	COG3201	nicotinamide mononucleotide transporter
AUC65_RS04705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUC65_RS04710	COG0248	Ppx GppA phosphatase
AUC65_RS04715	COG0604	alcohol dehydrogenase
AUC65_RS04715	COG3321	synthase
AUC65_RS04735	COG2801	Transposase and inactivated derivatives
AUC65_RS04790	COG2801	Transposase and inactivated derivatives
AUC65_RS04820	COG0277	FAD linked oxidase domain protein
AUC65_RS04825	COG0436	Aminotransferase
AUC65_RS04840	COG1464	Belongs to the NlpA lipoprotein family
AUC65_RS04850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AUC65_RS04855	COG0351	phosphomethylpyrimidine kinase
AUC65_RS04860	COG0352	thiamine-phosphate diphosphorylase activity
AUC65_RS04880	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_RS04890	COG1940	carbohydrate kinase activity
AUC65_RS04970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUC65_RS04975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC65_RS04990	COG2357	RelA SpoT domain protein
AUC65_RS04995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUC65_RS05000	COG0564	pseudouridine synthase activity
AUC65_RS05005	COG2239	Acts as a magnesium transporter
AUC65_RS05010	COG2814	Major facilitator Superfamily
AUC65_RS05025	COG0488	(ABC) transporter
AUC65_RS05030	COG0488	(ABC) transporter
AUC65_RS05065	COG0583	DNA-binding transcription factor activity
AUC65_RS05075	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS05080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUC65_RS05090	COG1846	Transcriptional regulator
AUC65_RS05145	COG0384	phenazine biosynthesis protein PhzF
AUC65_RS05155	COG1621	beta-fructofuranosidase activity
AUC65_RS05160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC65_RS05165	COG0287	Prephenate dehydrogenase
AUC65_RS05175	COG0738	Major facilitator superfamily
AUC65_RS05180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC65_RS05200	COG1304	FMN binding
AUC65_RS05215	COG0779	Required for maturation of 30S ribosomal subunits
AUC65_RS05220	COG0195	Participates in both transcription termination and antitermination
AUC65_RS05225	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AUC65_RS05235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUC65_RS05240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUC65_RS05245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUC65_RS05250	COG1252	NADH dehydrogenase
AUC65_RS05260	COG0196	riboflavin kinase activity
AUC65_RS05265	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AUC65_RS05270	COG3142	Participates in the control of copper homeostasis
AUC65_RS05285	COG2270	Major facilitator Superfamily
AUC65_RS05290	COG1307	EDD domain protein, DegV family
AUC65_RS05295	COG1307	EDD domain protein, DegV family
AUC65_RS05300	COG2755	lipolytic protein G-D-S-L family
AUC65_RS05310	COG4479	Belongs to the UPF0346 family
AUC65_RS05320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUC65_RS05325	COG0758	DNA mediated transformation
AUC65_RS05330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUC65_RS05335	COG4974	Belongs to the 'phage' integrase family
AUC65_RS05345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AUC65_RS05365	COG3448	diguanylate cyclase activity
AUC65_RS05365	COG4175	Glycine betaine
AUC65_RS05375	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_RS05380	COG1464	Belongs to the NlpA lipoprotein family
AUC65_RS05385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC65_RS05390	COG1597	lipid kinase activity
AUC65_RS05395	COG1011	Hydrolase
AUC65_RS05415	COG5503	Protein of unknown function (DUF1447)
AUC65_RS05430	COG0242	peptide deformylase activity
AUC65_RS05435	COG4476	Belongs to the UPF0223 family
AUC65_RS05440	COG0483	inositol monophosphate 1-phosphatase activity
AUC65_RS05445	COG1217	gtp-binding protein TYPA
AUC65_RS05450	COG0772	Belongs to the SEDS family
AUC65_RS05455	COG4471	UPF0298 protein
AUC65_RS05460	COG0742	ribosomal rna small subunit methyltransferase
AUC65_RS05465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUC65_RS05470	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUC65_RS05475	COG0477	Major facilitator Superfamily
AUC65_RS05485	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AUC65_RS05490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC65_RS05495	COG0358	DNA primase activity
AUC65_RS05500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUC65_RS05530	COG0745	RESPONSE REGULATOR receiver
AUC65_RS05535	COG5002	protein histidine kinase activity
AUC65_RS05540	COG0572	uridine kinase
AUC65_RS05545	COG1363	Peptidase, m42
AUC65_RS05550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_RS05560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUC65_RS05565	COG0670	Belongs to the BI1 family
AUC65_RS05570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC65_RS05570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC65_RS05575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUC65_RS05580	COG0237	dephospho-CoA kinase activity
AUC65_RS05590	COG1484	DNA-dependent DNA replication
AUC65_RS05605	COG0745	RESPONSE REGULATOR receiver
AUC65_RS05610	COG5002	protein histidine kinase activity
AUC65_RS05620	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_RS05620	COG3942	CHAP domain
AUC65_RS05645	COG0706	membrane insertase activity
AUC65_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_RS05655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_RS05665	COG1304	FMN binding
AUC65_RS05685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AUC65_RS05685	COG1199	ATP-dependent helicase activity
AUC65_RS05695	COG0017	Asparaginyl-tRNA synthetase
AUC65_RS05700	COG3935	DnaD domain protein
AUC65_RS05710	COG3331	DNA recombination
AUC65_RS05715	COG4474	Belongs to the UPF0398 family
AUC65_RS05720	COG3599	regulation of cell shape
AUC65_RS05730	COG0116	Belongs to the methyltransferase superfamily
AUC65_RS05740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUC65_RS05760	COG0556	nucleotide-excision repair
AUC65_RS05770	COG0439	Biotin carboxylase
AUC65_RS05775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC65_RS05785	COG3104	oligopeptide transport
AUC65_RS05790	COG0363	glucosamine-6-phosphate deaminase activity
AUC65_RS05800	COG0537	adenosine 5'-monophosphoramidase activity
AUC65_RS05805	COG1131	(ABC) transporter
AUC65_RS05815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AUC65_RS05820	COG1719	4-vinyl reductase, 4VR
AUC65_RS05825	COG1397	ADP-ribosylglycohydrolase
AUC65_RS05855	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_RS05860	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AUC65_RS05865	COG1349	DNA-binding transcription factor activity
AUC65_RS05870	COG1105	Belongs to the carbohydrate kinase PfkB family
AUC65_RS05875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC65_RS05875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC65_RS05875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC65_RS05885	COG1609	Transcriptional regulator
AUC65_RS05895	COG0306	phosphate transporter
AUC65_RS05905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUC65_RS05915	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS05935	COG0531	amino acid
AUC65_RS05945	COG0481	GTPase activity
AUC65_RS05975	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_RS05980	COG4708	membrane
AUC65_RS05990	COG0531	amino acid
AUC65_RS05995	COG4221	oxidoreductase activity
AUC65_RS06000	COG0583	DNA-binding transcription factor activity
AUC65_RS06005	COG0281	malic enzyme
AUC65_RS06015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC65_RS06030	COG1136	(ABC) transporter
AUC65_RS06035	COG0577	efflux transmembrane transporter activity
AUC65_RS06045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AUC65_RS06055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUC65_RS06060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUC65_RS06090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUC65_RS06095	COG2384	SAM-dependent methyltransferase
AUC65_RS06100	COG0071	Belongs to the small heat shock protein (HSP20) family
AUC65_RS06105	COG0457	Tetratricopeptide repeat
AUC65_RS06140	COG0419	ATPase involved in DNA repair
AUC65_RS06145	COG0420	3'-5' exonuclease activity
AUC65_RS06155	COG2807	transmembrane transport
AUC65_RS06160	COG4720	Psort location CytoplasmicMembrane, score
AUC65_RS06165	COG0351	phosphomethylpyrimidine kinase
AUC65_RS06175	COG1160	GTP binding
AUC65_RS06180	COG0539	negative regulation of cytoplasmic translation
AUC65_RS06185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUC65_RS06195	COG0514	ATP-dependent DNA helicase (RecQ)
AUC65_RS06205	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AUC65_RS06220	COG1187	pseudouridine synthase activity
AUC65_RS06225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUC65_RS06230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AUC65_RS06245	COG2996	Protein conserved in bacteria
AUC65_RS06255	COG0475	glutathione-regulated potassium exporter activity
AUC65_RS06265	COG1490	D-aminoacyl-tRNA deacylase activity
AUC65_RS06270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUC65_RS06275	COG0587	DNA-directed DNA polymerase activity
AUC65_RS06285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUC65_RS06290	COG0488	(ABC) transporter
AUC65_RS06295	COG0617	tRNA 3'-terminal CCA addition
AUC65_RS06315	COG1266	CAAX protease self-immunity
AUC65_RS06320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUC65_RS06325	COG0004	ammonium transporteR
AUC65_RS06335	COG5263	repeat protein
AUC65_RS06335	COG0366	Alpha amylase catalytic
AUC65_RS06340	COG1316	TRANSCRIPTIONal
AUC65_RS06345	COG1216	Glycosyl transferase, family 2
AUC65_RS06360	COG1216	Glycosyl transferase, family 2
AUC65_RS06370	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS06375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC65_RS06380	COG0489	protein tyrosine kinase activity
AUC65_RS06395	COG0233	cytoplasmic translational termination
AUC65_RS06405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUC65_RS06410	COG0052	Belongs to the universal ribosomal protein uS2 family
AUC65_RS06415	COG2827	Endonuclease containing a URI domain
AUC65_RS06420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AUC65_RS06425	COG0204	Acyl-transferase
AUC65_RS06430	COG0791	NLP P60 protein
AUC65_RS06430	COG3883	PFAM NLP P60 protein
AUC65_RS06445	COG3763	UPF0154 protein
AUC65_RS06450	COG4224	UPF0291 protein
AUC65_RS06455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUC65_RS06475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AUC65_RS06475	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AUC65_RS06480	COG1234	tRNA 3'-trailer cleavage
AUC65_RS06495	COG0484	heat shock protein binding
AUC65_RS06500	COG0443	Heat shock 70 kDa protein
AUC65_RS06510	COG1420	regulation of RNA biosynthetic process
AUC65_RS06540	COG1216	Glycosyl transferase, family 2
AUC65_RS06550	COG0463	Glycosyl transferase, family 2
AUC65_RS06560	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_RS06575	COG0562	UDP-galactopyranose mutase
AUC65_RS06600	COG0024	Methionine aminopeptidase
AUC65_RS06630	COG2801	Transposase and inactivated derivatives
AUC65_RS06665	COG2309	aminopeptidase activity
AUC65_RS06680	COG0564	pseudouridine synthase activity
AUC65_RS06685	COG1278	Cold shock
AUC65_RS06695	COG2814	Major facilitator Superfamily
AUC65_RS06700	COG0741	lytic transglycosylase activity
AUC65_RS06710	COG3973	AAA domain
AUC65_RS06720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUC65_RS06725	COG1546	Belongs to the CinA family
AUC65_RS06725	COG1058	Belongs to the CinA family
AUC65_RS06730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AUC65_RS06735	COG1426	Protein conserved in bacteria
AUC65_RS06740	COG0612	Peptidase, M16
AUC65_RS06745	COG0612	Peptidase, M16
AUC65_RS06760	COG0028	Belongs to the TPP enzyme family
AUC65_RS06780	COG4717	serine-type aminopeptidase activity
AUC65_RS06795	COG3679	Belongs to the UPF0342 family
AUC65_RS06800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUC65_RS06805	COG1438	arginine binding
AUC65_RS06835	COG1959	2 iron, 2 sulfur cluster binding
AUC65_RS06860	COG0018	arginyl-trna synthetase
AUC65_RS06875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC65_RS06885	COG1121	(ABC) transporter
AUC65_RS06905	COG1597	lipid kinase activity
AUC65_RS06910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC65_RS06915	COG0154	amidase activity
AUC65_RS06920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC65_RS06925	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AUC65_RS06925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC65_RS06935	COG2936	dipeptidyl-peptidase activity
AUC65_RS06950	COG1695	Transcriptional regulator
AUC65_RS06960	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC65_RS06980	COG0667	Aldo Keto reductase
AUC65_RS06985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC65_RS06990	COG4721	ABC-type cobalt transport system, permease component
AUC65_RS06995	COG1122	ATPase activity
AUC65_RS07010	COG0758	DNA mediated transformation
AUC65_RS07030	COG0710	3-dehydroquinate dehydratase activity
AUC65_RS07035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AUC65_RS07040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC65_RS07045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC65_RS07050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUC65_RS07055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AUC65_RS07060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUC65_RS07075	COG4684	Psort location CytoplasmicMembrane, score
AUC65_RS07080	COG0436	Aminotransferase
AUC65_RS07100	COG2801	Transposase and inactivated derivatives
AUC65_RS07115	COG1783	phage Terminase large subunit
AUC65_RS07260	COG1396	sequence-specific DNA binding
AUC65_RS07295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUC65_RS07300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AUC65_RS07305	COG0436	Aminotransferase
AUC65_RS07310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUC65_RS07315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUC65_RS07325	COG2171	N-acyltransferase activity
AUC65_RS07335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUC65_RS07340	COG0527	aspartate kinase activity
AUC65_RS07350	COG1609	Transcriptional regulator
AUC65_RS07355	COG0083	homoserine kinase activity
AUC65_RS07370	COG1321	iron dependent repressor
AUC65_RS07375	COG3764	Sortase (surface protein transpeptidase)
AUC65_RS07395	COG0513	Belongs to the DEAD box helicase family
AUC65_RS07400	COG0673	inositol 2-dehydrogenase activity
AUC65_RS07405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_RS07415	COG0501	Belongs to the peptidase M48B family
AUC65_RS07420	COG1704	LemA family
AUC65_RS07430	COG4115	mRNA cleavage
AUC65_RS07435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC65_RS07450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC65_RS07460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC65_RS07465	COG0439	Biotin carboxylase
AUC65_RS07480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AUC65_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_RS07490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AUC65_RS07495	COG2070	2-Nitropropane dioxygenase
AUC65_RS07500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC65_RS07505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC65_RS07510	COG1846	Transcriptional regulator
AUC65_RS07515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AUC65_RS07525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUC65_RS07530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AUC65_RS07540	COG0505	Belongs to the CarA family
AUC65_RS07550	COG0564	pseudouridine synthase activity
AUC65_RS07560	COG0328	RNA-DNA hybrid ribonuclease activity
AUC65_RS07565	COG1757	Na H antiporter
AUC65_RS07570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AUC65_RS07575	COG1113	amino acid transport
AUC65_RS07600	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS07610	COG1012	belongs to the aldehyde dehydrogenase family
AUC65_RS07610	COG1454	alcohol dehydrogenase
AUC65_RS07615	COG0105	UTP biosynthetic process
AUC65_RS07625	COG0583	DNA-binding transcription factor activity
AUC65_RS07630	COG0126	phosphoglycerate kinase activity
AUC65_RS07680	COG0588	phosphoglycerate mutase activity
AUC65_RS07690	COG3716	PTS system mannose fructose sorbose family IID component
AUC65_RS07695	COG3715	PTS system
AUC65_RS07710	COG1397	ADP-ribosylglycohydrolase
AUC65_RS07770	COG1368	sulfuric ester hydrolase activity
AUC65_RS07785	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS07790	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS07795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUC65_RS07800	COG0284	orotidine-5'-phosphate decarboxylase activity
AUC65_RS07805	COG0167	dihydroorotate dehydrogenase activity
AUC65_RS07810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC65_RS07815	COG0505	Belongs to the CarA family
AUC65_RS07820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUC65_RS07825	COG0540	Belongs to the ATCase OTCase family
AUC65_RS07845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC65_RS07850	COG4856	YbbR-like protein
AUC65_RS07865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUC65_RS07880	COG0802	atpase or kinase
AUC65_RS07885	COG0280	phosphate acetyltransferase
AUC65_RS07890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUC65_RS07900	COG2076	Multidrug Resistance protein
AUC65_RS07905	COG2076	Multidrug Resistance protein
AUC65_RS07910	COG1126	abc transporter atp-binding protein
AUC65_RS07915	COG0765	amino acid transport
AUC65_RS07920	COG2814	Major facilitator Superfamily
AUC65_RS07935	COG0557	exoribonuclease II activity
AUC65_RS07945	COG2814	Major facilitator Superfamily
AUC65_RS07950	COG0154	amidase activity
AUC65_RS07970	COG0149	triose-phosphate isomerase activity
AUC65_RS07975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUC65_RS07980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC65_RS07990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC65_RS07995	COG0492	ferredoxin-NADP+ reductase activity
AUC65_RS08020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AUC65_RS08025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUC65_RS08030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AUC65_RS08035	COG1950	PFAM Membrane protein of
AUC65_RS08045	COG0589	response to stress
AUC65_RS08055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC65_RS08065	COG1177	transmembrane transport
AUC65_RS08075	COG3842	ATPase activity
AUC65_RS08085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUC65_RS08090	COG0049	tRNA binding
AUC65_RS08095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUC65_RS08105	COG4608	Belongs to the ABC transporter superfamily
AUC65_RS08110	COG0444	Belongs to the ABC transporter superfamily
AUC65_RS08115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_RS08120	COG0601	transmembrane transport
AUC65_RS08130	COG0460	homoserine dehydrogenase
AUC65_RS08135	COG0626	cystathionine gamma-synthase activity
AUC65_RS08140	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AUC65_RS08150	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS08155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUC65_RS08160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUC65_RS08175	COG1302	Protein conserved in bacteria
AUC65_RS08180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUC65_RS08190	COG2017	converts alpha-aldose to the beta-anomer
AUC65_RS08200	COG4975	Glucose uptake
AUC65_RS08205	COG3850	Histidine kinase
AUC65_RS08205	COG5002	protein histidine kinase activity
AUC65_RS08210	COG0745	RESPONSE REGULATOR receiver
AUC65_RS08215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_RS08220	COG0402	S-adenosylhomocysteine deaminase activity
AUC65_RS08225	COG0673	inositol 2-dehydrogenase activity
AUC65_RS08230	COG0741	lytic transglycosylase activity
AUC65_RS08250	COG0668	transmembrane transport
AUC65_RS08260	COG1126	abc transporter atp-binding protein
AUC65_RS08295	COG0516	GMP reductase activity
AUC65_RS08365	COG2801	Transposase and inactivated derivatives
AUC65_RS08380	COG0494	nUDIX hydrolase
AUC65_RS08415	COG0738	Major facilitator superfamily
AUC65_RS08420	COG1869	D-ribose catabolic process
AUC65_RS08425	COG1609	Transcriptional regulator
AUC65_RS08445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC65_RS08460	COG1609	Transcriptional regulator
AUC65_RS08480	COG2223	nitrite transmembrane transporter activity
AUC65_RS08490	COG0318	PFAM AMP-dependent synthetase and ligase
AUC65_RS08500	COG1116	anion transmembrane transporter activity
AUC65_RS08505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUC65_RS08515	COG0285	dihydrofolate synthase activity
AUC65_RS08520	COG0302	gtp cyclohydrolase
AUC65_RS08525	COG0302	gtp cyclohydrolase
AUC65_RS08525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AUC65_RS08565	COG0561	phosphatase activity
AUC65_RS08580	COG0823	Involved in the tonB-independent uptake of proteins
AUC65_RS08580	COG4946	Tricorn protease homolog
AUC65_RS08580	COG1506	peptidase
AUC65_RS08585	COG1464	Belongs to the NlpA lipoprotein family
AUC65_RS08590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC65_RS08595	COG0800	Aldolase
AUC65_RS08600	COG1904	glucuronate isomerase
AUC65_RS08605	COG1312	Catalyzes the dehydration of D-mannonate
AUC65_RS08610	COG0246	Mannitol dehydrogenase
AUC65_RS08625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUC65_RS08640	COG1609	Transcriptional regulator
AUC65_RS08670	COG0577	efflux transmembrane transporter activity
AUC65_RS08675	COG1136	(ABC) transporter
AUC65_RS08680	COG3759	membrane
AUC65_RS08705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC65_RS08710	COG2235	arginine
AUC65_RS08720	COG2217	Heavy metal translocating P-type atpase
AUC65_RS08770	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS08810	COG2814	Major facilitator Superfamily
AUC65_RS08815	COG2217	Heavy metal translocating P-type atpase
AUC65_RS08835	COG1309	transcriptional regulator
AUC65_RS08855	COG3711	transcriptional antiterminator
AUC65_RS08860	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS08865	COG1940	carbohydrate kinase activity
AUC65_RS08890	COG2183	response to ionizing radiation
AUC65_RS08900	COG2873	o-acetylhomoserine
AUC65_RS08905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AUC65_RS08910	COG1040	competence protein
AUC65_RS08915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AUC65_RS08995	COG2176	DNA-directed DNA polymerase activity
AUC65_RS09000	COG0442	prolyl-tRNA aminoacylation
AUC65_RS09005	COG0750	zinc metalloprotease
AUC65_RS09010	COG4589	Belongs to the CDS family
AUC65_RS09015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUC65_RS09020	COG0561	phosphatase activity
AUC65_RS09025	COG2246	polysaccharide biosynthetic process
AUC65_RS09050	COG1811	Na channel or pump
AUC65_RS09055	COG1979	alcohol dehydrogenase
AUC65_RS09065	COG1174	glycine betaine transport
AUC65_RS09085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUC65_RS09090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_RS09090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_RS09095	COG0307	riboflavin synthase, alpha
AUC65_RS09105	COG2076	Multidrug Resistance protein
AUC65_RS09110	COG2076	Multidrug Resistance protein
AUC65_RS09115	COG1435	thymidine kinase activity
AUC65_RS09130	COG1307	EDD domain protein, DegV family
AUC65_RS09135	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS09140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC65_RS09145	COG2814	Major facilitator Superfamily
AUC65_RS09160	COG1228	amidohydrolase
AUC65_RS09165	COG4166	transmembrane transport
AUC65_RS09170	COG0604	alcohol dehydrogenase
AUC65_RS09210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AUC65_RS09215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUC65_RS09225	COG2252	PERMEase
AUC65_RS09235	COG0352	thiamine-phosphate diphosphorylase activity
AUC65_RS09240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AUC65_RS09250	COG2814	Major facilitator Superfamily
AUC65_RS09255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUC65_RS09265	COG2188	Transcriptional regulator
AUC65_RS09275	COG0577	efflux transmembrane transporter activity
AUC65_RS09275	COG1136	(ABC) transporter
AUC65_RS09285	COG0561	phosphatase activity
AUC65_RS09290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUC65_RS09290	COG2169	Transcriptional regulator
AUC65_RS09295	COG0561	phosphatase activity
AUC65_RS09315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUC65_RS09320	COG0772	Belongs to the SEDS family
AUC65_RS09330	COG1077	Cell shape determining protein MreB Mrl
AUC65_RS09335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC65_RS09340	COG1079	Belongs to the binding-protein-dependent transport system permease family
AUC65_RS09345	COG4603	Belongs to the binding-protein-dependent transport system permease family
AUC65_RS09350	COG3845	ABC transporter
AUC65_RS09355	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS09360	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_RS09370	COG0640	Transcriptional regulator
AUC65_RS09375	COG0628	permease
AUC65_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_RS09400	COG0386	Belongs to the glutathione peroxidase family
AUC65_RS09405	COG0588	phosphoglycerate mutase activity
AUC65_RS09420	COG0492	ferredoxin-NADP+ reductase activity
AUC65_RS09435	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS09440	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_RS09450	COG2832	Protein of unknown function (DUF454)
AUC65_RS09475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC65_RS09485	COG2814	Major facilitator Superfamily
AUC65_RS09490	COG0305	Participates in initiation and elongation during chromosome replication
AUC65_RS09495	COG0359	binds to the 23S rRNA
AUC65_RS09505	COG4608	Belongs to the ABC transporter superfamily
AUC65_RS09510	COG0444	Belongs to the ABC transporter superfamily
AUC65_RS09515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_RS09520	COG0601	transmembrane transport
AUC65_RS09525	COG4166	transmembrane transport
AUC65_RS09530	COG0765	amino acid transport
AUC65_RS09535	COG0765	amino acid transport
AUC65_RS09540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_RS09545	COG1126	abc transporter atp-binding protein
AUC65_RS09560	COG0194	GDP metabolic process
AUC65_RS09565	COG1268	BioY protein
AUC65_RS09570	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AUC65_RS09570	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AUC65_RS09595	COG2211	Major facilitator Superfamily
AUC65_RS09600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AUC65_RS09615	COG3973	AAA domain
AUC65_RS09635	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AUC65_RS09645	COG1696	Membrane protein involved in D-alanine export
AUC65_RS09665	COG2337	Toxic component of a toxin-antitoxin (TA) module
AUC65_RS09680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUC65_RS09685	COG0504	CTP synthase activity
AUC65_RS09695	COG3343	RNA polymerase activity
AUC65_RS09700	COG0561	phosphatase activity
AUC65_RS09705	COG1078	dGTPase activity
AUC65_RS09715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUC65_RS09720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AUC65_RS09740	COG0745	RESPONSE REGULATOR receiver
AUC65_RS09770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUC65_RS09775	COG0629	single-stranded DNA binding
AUC65_RS09780	COG0360	Binds together with S18 to 16S ribosomal RNA
AUC65_RS09795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC65_RS09805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC65_RS09810	COG1051	belongs to the nudix hydrolase family
AUC65_RS09825	COG2814	Major facilitator Superfamily
AUC65_RS09830	COG1064	alcohol dehydrogenase
AUC65_RS09835	COG1074	ATP-dependent DNA helicase activity
AUC65_RS09840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AUC65_RS09855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC65_RS09860	COG0531	amino acid
AUC65_RS09865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AUC65_RS09875	COG1902	pentaerythritol trinitrate reductase activity
AUC65_RS09880	COG0626	cystathionine gamma-synthase activity
AUC65_RS09895	COG2244	polysaccharide biosynthetic process
AUC65_RS09905	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS09910	COG0495	leucyl-tRNA aminoacylation
AUC65_RS09915	COG0671	phosphoesterase, PA-phosphatase related
AUC65_RS09925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_RS09950	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS09965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC65_RS09975	COG2801	Transposase and inactivated derivatives
AUC65_RS09985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC65_RS09995	COG0024	Methionine aminopeptidase
AUC65_RS10005	COG1316	TRANSCRIPTIONal
AUC65_RS10015	COG2205	protein histidine kinase activity
AUC65_RS10020	COG0745	RESPONSE REGULATOR receiver
AUC65_RS10025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC65_RS10040	COG2207	Transcriptional regulator
AUC65_RS10060	COG0308	aminopeptidase N
AUC65_RS10065	COG0833	amino acid
AUC65_RS10070	COG2040	homocysteine
AUC65_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_RS10080	COG0542	response to heat
AUC65_RS10095	COG0395	ABC-type sugar transport system, permease component
AUC65_RS10100	COG1175	transmembrane transport
AUC65_RS10105	COG3842	ATPase activity
AUC65_RS10215	COG0438	transferase activity, transferring glycosyl groups
AUC65_RS10245	COG2084	Dehydrogenase
AUC65_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_RS10260	COG1620	l-lactate permease
AUC65_RS10265	COG4989	oxidoreductase activity
AUC65_RS10270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC65_RS10275	COG2233	PERMEase
AUC65_RS10290	COG1956	GAF domain-containing protein
AUC65_RS10305	COG1132	(ABC) transporter
AUC65_RS10315	COG0747	negative chemotaxis
AUC65_RS10320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_RS10325	COG0601	transmembrane transport
AUC65_RS10330	COG4608	Belongs to the ABC transporter superfamily
AUC65_RS10335	COG0444	Belongs to the ABC transporter superfamily
AUC65_RS10340	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AUC65_RS10345	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AUC65_RS10350	COG2190	(PTS) system
AUC65_RS10350	COG2211	Major facilitator Superfamily
AUC65_RS10370	COG0436	Aminotransferase
AUC65_RS10380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_RS10385	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS10390	COG2723	6-phospho-beta-galactosidase activity
AUC65_RS10395	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC65_RS10400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_RS10405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUC65_RS10420	COG1216	Glycosyl transferase, family 2
AUC65_RS10435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUC65_RS10480	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AUC65_RS10485	COG1737	Transcriptional regulator
AUC65_RS10495	COG0656	L-ascorbic acid biosynthetic process
AUC65_RS10500	COG2261	transglycosylase associated protein
AUC65_RS10565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUC65_RS10570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AUC65_RS10585	COG0037	tRNA processing
AUC65_RS10595	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AUC65_RS10600	COG2244	polysaccharide biosynthetic process
AUC65_RS10605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AUC65_RS10610	COG0193	aminoacyl-tRNA hydrolase activity
AUC65_RS10620	COG0058	SHG alpha-glucan phosphorylase activity
AUC65_RS10625	COG0297	glycogen (starch) synthase activity
AUC65_RS10630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUC65_RS10640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUC65_RS10645	COG1511	domain protein
AUC65_RS10645	COG1511	domain protein
AUC65_RS10650	COG1309	transcriptional regulator
AUC65_RS10665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_RS10670	COG0477	Major facilitator Superfamily
AUC65_RS10685	COG0667	Aldo Keto reductase
AUC65_RS10695	COG2115	Belongs to the xylose isomerase family
AUC65_RS10705	COG2211	Major facilitator Superfamily
AUC65_RS10710	COG3507	Belongs to the glycosyl hydrolase 43 family
AUC65_RS10735	COG2818	Glycosylase
AUC65_RS10740	COG1968	undecaprenyl-diphosphatase activity
AUC65_RS10755	COG1695	Transcriptional regulator
AUC65_RS10760	COG1983	PspC domain protein
AUC65_RS10765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AUC65_RS10770	COG0737	Belongs to the 5'-nucleotidase family
AUC65_RS10785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AUC65_RS10800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_RS10800	COG1263	PTS System
AUC65_RS10805	COG1316	TRANSCRIPTIONal
AUC65_RS10815	COG2131	deaminase
AUC65_RS10820	COG4466	Protein conserved in bacteria
AUC65_RS10825	COG1253	flavin adenine dinucleotide binding
AUC65_RS10830	COG1253	flavin adenine dinucleotide binding
AUC65_RS10835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUC65_RS10840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AUC65_RS10845	COG0084	hydrolase, TatD family'
AUC65_RS10855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_RS10855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_RS10940	COG2153	protein acetylation
AUC65_RS10955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AUC65_RS10965	COG2801	Transposase and inactivated derivatives
AUC65_RS10970	COG2910	NAD(P)H-binding
AUC65_RS10975	COG1733	regulation of RNA biosynthetic process
AUC65_RS11000	COG1573	uracil-dna glycosylase
AUC65_RS11005	COG2801	Transposase and inactivated derivatives
AUC65_RS11050	COG0783	Belongs to the Dps family
AUC65_RS11055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein