locus-tag	class	description
C6P13_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C6P13_RS00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C6P13_RS00015	COG0594	ribonuclease P activity
C6P13_RS00030	COG1120	ATPase activity
C6P13_RS00035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P13_RS00040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C6P13_RS00060	COG0569	domain protein
C6P13_RS00065	COG1113	amino acid transport
C6P13_RS00105	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C6P13_RS00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6P13_RS00115	COG0561	phosphatase activity
C6P13_RS00125	COG0328	RNA-DNA hybrid ribonuclease activity
C6P13_RS00150	COG2252	PERMEase
C6P13_RS00155	COG0431	NADPH-dependent FMN reductase
C6P13_RS00160	COG1846	Transcriptional regulator
C6P13_RS00175	COG0149	triose-phosphate isomerase activity
C6P13_RS00195	COG1881	PFAM PEBP family protein
C6P13_RS00215	COG1125	glycine betaine transport
C6P13_RS00215	COG0517	IMP dehydrogenase activity
C6P13_RS00220	COG1732	Glycine betaine
C6P13_RS00230	COG1464	Belongs to the NlpA lipoprotein family
C6P13_RS00235	COG0823	Involved in the tonB-independent uptake of proteins
C6P13_RS00235	COG1506	peptidase
C6P13_RS00235	COG4946	Tricorn protease homolog
C6P13_RS00265	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS00285	COG1388	LysM domain
C6P13_RS00300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6P13_RS00305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6P13_RS00320	COG0697	spore germination
C6P13_RS00340	COG1846	Transcriptional regulator
C6P13_RS00345	COG1132	(ABC) transporter
C6P13_RS00355	COG0656	L-ascorbic acid biosynthetic process
C6P13_RS00365	COG4619	ABC transporter
C6P13_RS00370	COG0390	transport system, permease component
C6P13_RS00375	COG1126	abc transporter atp-binding protein
C6P13_RS00380	COG0765	amino acid transport
C6P13_RS00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P13_RS00390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P13_RS00395	COG1254	Belongs to the acylphosphatase family
C6P13_RS00405	COG0392	lysyltransferase activity
C6P13_RS00405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C6P13_RS00415	COG0628	permease
C6P13_RS00445	COG1113	amino acid transport
C6P13_RS00470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6P13_RS00480	COG2855	membrane
C6P13_RS00500	COG1228	amidohydrolase
C6P13_RS00505	COG0531	amino acid
C6P13_RS00515	COG4975	Glucose uptake
C6P13_RS00530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6P13_RS00540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6P13_RS00550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6P13_RS00555	COG1063	alcohol dehydrogenase
C6P13_RS00560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6P13_RS00565	COG0477	Major facilitator Superfamily
C6P13_RS00575	COG0531	amino acid
C6P13_RS00605	COG1113	amino acid transport
C6P13_RS00610	COG0531	amino acid
C6P13_RS00615	COG0252	asparaginase activity
C6P13_RS00620	COG4443	Transcriptional Coactivator p15 (PC4)
C6P13_RS00630	COG2226	methyltransferase
C6P13_RS00635	COG1335	isochorismatase
C6P13_RS00640	COG2050	protein possibly involved in aromatic compounds catabolism
C6P13_RS00645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6P13_RS00650	COG0318	PFAM AMP-dependent synthetase and ligase
C6P13_RS00665	COG0745	RESPONSE REGULATOR receiver
C6P13_RS00670	COG5002	protein histidine kinase activity
C6P13_RS00675	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6P13_RS00690	COG2207	Transcriptional regulator
C6P13_RS00700	COG1511	domain protein
C6P13_RS00715	COG1194	a g-specific adenine glycosylase
C6P13_RS00720	COG1957	nucleoside hydrolase
C6P13_RS00725	COG0357	Ribosomal RNA small subunit methyltransferase G
C6P13_RS00730	COG1192	Involved in chromosome partitioning
C6P13_RS00735	COG1475	DNA binding
C6P13_RS00740	COG4481	Protein conserved in bacteria
C6P13_RS00745	COG0012	GTP binding
C6P13_RS00755	COG0745	RESPONSE REGULATOR receiver
C6P13_RS00765	COG1686	Belongs to the peptidase S11 family
C6P13_RS00815	COG3104	oligopeptide transport
C6P13_RS00855	COG3091	SprT-like family
C6P13_RS00860	COG1979	alcohol dehydrogenase
C6P13_RS00865	COG2755	lipolytic protein G-D-S-L family
C6P13_RS00865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C6P13_RS00870	COG1846	Transcriptional regulator
C6P13_RS00880	COG1121	(ABC) transporter
C6P13_RS00890	COG0488	(ABC) transporter
C6P13_RS00895	COG0534	Mate efflux family protein
C6P13_RS00930	COG0765	amino acid transport
C6P13_RS00965	COG1418	mRNA catabolic process
C6P13_RS00970	COG2814	Major facilitator Superfamily
C6P13_RS00995	COG2188	Transcriptional regulator
C6P13_RS01000	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C6P13_RS01005	COG5039	Polysaccharide pyruvyl transferase
C6P13_RS01045	COG3590	peptidase
C6P13_RS01055	COG1454	alcohol dehydrogenase
C6P13_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
C6P13_RS01065	COG0708	Exodeoxyribonuclease III
C6P13_RS01070	COG1131	(ABC) transporter
C6P13_RS01090	COG0588	phosphoglycerate mutase activity
C6P13_RS01095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6P13_RS01105	COG1132	(ABC) transporter
C6P13_RS01110	COG1132	(ABC) transporter
C6P13_RS01140	COG1482	cell wall glycoprotein biosynthetic process
C6P13_RS01150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6P13_RS01155	COG3442	glutamine amidotransferase
C6P13_RS01165	COG1435	thymidine kinase activity
C6P13_RS01175	COG2890	protein-(glutamine-N5) methyltransferase activity
C6P13_RS01180	COG0009	L-threonylcarbamoyladenylate synthase
C6P13_RS01185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C6P13_RS01190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C6P13_RS01195	COG0702	epimerase
C6P13_RS01200	COG2233	PERMEase
C6P13_RS01205	COG0356	it plays a direct role in the translocation of protons across the membrane
C6P13_RS01210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C6P13_RS01215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C6P13_RS01220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C6P13_RS01225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C6P13_RS01230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C6P13_RS01235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C6P13_RS01240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C6P13_RS01245	COG1876	peptidase activity
C6P13_RS01250	COG1428	Deoxynucleoside kinase
C6P13_RS01255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C6P13_RS01260	COG1686	Belongs to the peptidase S11 family
C6P13_RS01285	COG4463	regulation of RNA biosynthetic process
C6P13_RS01290	COG0542	response to heat
C6P13_RS01295	COG0085	RNA polymerase activity
C6P13_RS01305	COG1979	alcohol dehydrogenase
C6P13_RS01325	COG0500	methyltransferase
C6P13_RS01360	COG2807	transmembrane transport
C6P13_RS01370	COG2813	Specifically methylates the guanine in position
C6P13_RS01385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6P13_RS01395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C6P13_RS01410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6P13_RS01415	COG3870	Protein conserved in bacteria
C6P13_RS01435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6P13_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
C6P13_RS01460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C6P13_RS01470	COG0051	transcription antitermination factor activity, RNA binding
C6P13_RS01475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C6P13_RS01485	COG0089	rRNA binding
C6P13_RS01490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C6P13_RS01495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C6P13_RS01500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C6P13_RS01505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C6P13_RS01510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C6P13_RS01515	COG0255	Belongs to the universal ribosomal protein uL29 family
C6P13_RS01525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C6P13_RS01530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C6P13_RS01535	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C6P13_RS01540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C6P13_RS01545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C6P13_RS01550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C6P13_RS01555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C6P13_RS01560	COG1841	ribosomal large subunit assembly
C6P13_RS01565	COG0200	Binds to the 23S rRNA
C6P13_RS01580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C6P13_RS01585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C6P13_RS01590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C6P13_RS01595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C6P13_RS01600	COG0202	RNA polymerase activity
C6P13_RS01605	COG0203	ribosomal protein L17
C6P13_RS01635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6P13_RS01650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C6P13_RS01660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6P13_RS01675	COG0215	cysteine-tRNA ligase activity
C6P13_RS01680	COG0626	cystathionine gamma-synthase activity
C6P13_RS01685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C6P13_RS01690	COG1464	Belongs to the NlpA lipoprotein family
C6P13_RS01695	COG1854	S-ribosylhomocysteine lyase activity
C6P13_RS01700	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C6P13_RS01705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P13_RS01720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6P13_RS01725	COG0250	Participates in transcription elongation, termination and antitermination
C6P13_RS01730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C6P13_RS01735	COG0081	regulation of translation
C6P13_RS01740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C6P13_RS01745	COG0222	ribosome binding
C6P13_RS01755	COG1121	(ABC) transporter
C6P13_RS01760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P13_RS01765	COG0803	Belongs to the bacterial solute-binding protein 9 family
C6P13_RS01770	COG1252	NADH dehydrogenase
C6P13_RS01780	COG1122	ATPase activity
C6P13_RS01785	COG1122	ATPase activity
C6P13_RS01795	COG0101	tRNA pseudouridine synthase activity
C6P13_RS01800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C6P13_RS01820	COG2814	Major facilitator Superfamily
C6P13_RS01830	COG0028	Belongs to the TPP enzyme family
C6P13_RS01835	COG1573	uracil-dna glycosylase
C6P13_RS01845	COG0366	Alpha amylase catalytic
C6P13_RS01855	COG0671	phosphoesterase, PA-phosphatase related
C6P13_RS01865	COG2814	Major facilitator Superfamily
C6P13_RS01870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6P13_RS01885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6P13_RS01890	COG1481	regulation of sporulation
C6P13_RS01895	COG0740	serine-type endopeptidase activity
C6P13_RS01910	COG2190	(PTS) system
C6P13_RS01910	COG1263	PTS System
C6P13_RS01910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P13_RS01920	COG1914	H( )-stimulated, divalent metal cation uptake system
C6P13_RS01940	COG4974	Belongs to the 'phage' integrase family
C6P13_RS01945	COG1396	sequence-specific DNA binding
C6P13_RS02015	COG1215	transferase activity, transferring glycosyl groups
C6P13_RS02030	COG0039	L-malate dehydrogenase activity
C6P13_RS02035	COG0028	Belongs to the TPP enzyme family
C6P13_RS02040	COG3527	Alpha-acetolactate decarboxylase
C6P13_RS02050	COG1388	LysM domain
C6P13_RS02050	COG0791	NLP P60 protein
C6P13_RS02065	COG0756	dUTP diphosphatase activity
C6P13_RS02075	COG4956	integral membrane protein (PIN domain superfamily)
C6P13_RS02085	COG0653	protein targeting
C6P13_RS02090	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6P13_RS02100	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C6P13_RS02125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P13_RS02145	COG1733	regulation of RNA biosynthetic process
C6P13_RS02150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C6P13_RS02155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6P13_RS02155	COG0072	phenylalanine-tRNA ligase activity
C6P13_RS02160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6P13_RS02170	COG0514	ATP-dependent DNA helicase (RecQ)
C6P13_RS02175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6P13_RS02185	COG0768	penicillin binding
C6P13_RS02190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6P13_RS02205	COG1940	carbohydrate kinase activity
C6P13_RS02215	COG4942	peptidase
C6P13_RS02220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6P13_RS02235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C6P13_RS02240	COG0789	Transcriptional regulator
C6P13_RS02245	COG0174	glutamine synthetase
C6P13_RS02270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C6P13_RS02275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C6P13_RS02290	COG0464	growth
C6P13_RS02295	COG1472	Belongs to the glycosyl hydrolase 3 family
C6P13_RS02310	COG1132	(ABC) transporter
C6P13_RS02315	COG1169	isochorismate synthase
C6P13_RS02320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C6P13_RS02325	COG0596	Alpha beta hydrolase
C6P13_RS02330	COG4948	Mandelate Racemase Muconate Lactonizing
C6P13_RS02335	COG0006	proline dipeptidase activity
C6P13_RS02355	COG4470	Protein conserved in bacteria
C6P13_RS02360	COG0647	UMP catabolic process
C6P13_RS02365	COG4166	transmembrane transport
C6P13_RS02370	COG0673	inositol 2-dehydrogenase activity
C6P13_RS02375	COG1957	nucleoside hydrolase
C6P13_RS02395	COG0573	inorganic phosphate transmembrane transporter activity
C6P13_RS02400	COG0581	inorganic phosphate transmembrane transporter activity
C6P13_RS02405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6P13_RS02410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6P13_RS02415	COG0704	Plays a role in the regulation of phosphate uptake
C6P13_RS02435	COG2137	regulation of response to DNA damage stimulus
C6P13_RS02465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6P13_RS02485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6P13_RS02495	COG0589	response to stress
C6P13_RS02570	COG1272	protein, Hemolysin III
C6P13_RS02585	COG0525	valine-tRNA ligase activity
C6P13_RS02590	COG0285	dihydrofolate synthase activity
C6P13_RS02605	COG0488	(ABC) transporter
C6P13_RS02610	COG2814	Major facilitator Superfamily
C6P13_RS02620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C6P13_RS02625	COG0459	protein refolding
C6P13_RS02630	COG0531	amino acid
C6P13_RS02640	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6P13_RS02645	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C6P13_RS02650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C6P13_RS02660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C6P13_RS02665	COG1713	HD superfamily hydrolase involved in NAD metabolism
C6P13_RS02670	COG0799	negative regulation of ribosome biogenesis
C6P13_RS02675	COG2226	methyltransferase
C6P13_RS02680	COG1323	Belongs to the UPF0348 family
C6P13_RS02690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C6P13_RS02695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C6P13_RS02720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C6P13_RS02725	COG0363	glucosamine-6-phosphate deaminase activity
C6P13_RS02740	COG0577	efflux transmembrane transporter activity
C6P13_RS02745	COG1136	(ABC) transporter
C6P13_RS02760	COG4720	Psort location CytoplasmicMembrane, score
C6P13_RS02765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C6P13_RS02780	COG0142	geranyltranstransferase activity
C6P13_RS02785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C6P13_RS02790	COG1438	arginine binding
C6P13_RS02795	COG0497	DNA recombination
C6P13_RS02805	COG0194	GDP metabolic process
C6P13_RS02810	COG1758	RNA polymerase activity
C6P13_RS02815	COG0586	Pfam SNARE associated Golgi protein
C6P13_RS02825	COG1098	S1 RNA binding domain
C6P13_RS02935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6P13_RS02940	COG4684	Psort location CytoplasmicMembrane, score
C6P13_RS02945	COG1271	oxidase subunit
C6P13_RS02950	COG1294	oxidase, subunit
C6P13_RS02955	COG4988	ABC transporter
C6P13_RS02960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6P13_RS02965	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6P13_RS02970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6P13_RS02985	COG1278	Cold shock
C6P13_RS02990	COG0494	nUDIX hydrolase
C6P13_RS03000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6P13_RS03005	COG0346	lactoylglutathione lyase activity
C6P13_RS03010	COG0400	carboxylic ester hydrolase activity
C6P13_RS03020	COG0741	lytic transglycosylase activity
C6P13_RS03040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6P13_RS03045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6P13_RS03060	COG4120	Belongs to the binding-protein-dependent transport system permease family
C6P13_RS03070	COG0038	chloride channel
C6P13_RS03075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6P13_RS03080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6P13_RS03085	COG1307	EDD domain protein, DegV family
C6P13_RS03090	COG1263	PTS System
C6P13_RS03090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P13_RS03090	COG2190	(PTS) system
C6P13_RS03105	COG2003	Belongs to the UPF0758 family
C6P13_RS03110	COG1077	Cell shape determining protein MreB Mrl
C6P13_RS03130	COG0765	amino acid transport
C6P13_RS03135	COG1126	abc transporter atp-binding protein
C6P13_RS03140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P13_RS03145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6P13_RS03145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6P13_RS03150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6P13_RS03155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6P13_RS03165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6P13_RS03170	COG0047	phosphoribosylformylglycinamidine synthase activity
C6P13_RS03175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6P13_RS03190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6P13_RS03195	COG0138	bifunctional purine biosynthesis protein purh
C6P13_RS03200	COG0151	Belongs to the GarS family
C6P13_RS03205	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C6P13_RS03220	COG0833	amino acid
C6P13_RS03230	COG2264	protein methyltransferase activity
C6P13_RS03235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6P13_RS03245	COG2001	Belongs to the MraZ family
C6P13_RS03250	COG0275	rRNA processing
C6P13_RS03260	COG0768	penicillin binding
C6P13_RS03265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6P13_RS03270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C6P13_RS03275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C6P13_RS03280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6P13_RS03285	COG0849	cell division
C6P13_RS03295	COG1799	cell septum assembly
C6P13_RS03310	COG3599	regulation of cell shape
C6P13_RS03320	COG0406	alpha-ribazole phosphatase activity
C6P13_RS03330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6P13_RS03335	COG0217	transcriptional regulatory protein
C6P13_RS03340	COG2252	PERMEase
C6P13_RS03345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6P13_RS03385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6P13_RS03415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6P13_RS03420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C6P13_RS03425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6P13_RS03425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6P13_RS03435	COG0515	serine threonine protein kinase
C6P13_RS03435	COG2815	serine threonine protein kinase
C6P13_RS03440	COG1162	GTPase activity
C6P13_RS03445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6P13_RS03450	COG1564	THIamine pyrophosphokinase
C6P13_RS03455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C6P13_RS03465	COG1461	Dihydroxyacetone kinase
C6P13_RS03485	COG2211	Major facilitator Superfamily
C6P13_RS03490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6P13_RS03495	COG0416	fatty acid biosynthetic process
C6P13_RS03500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6P13_RS03505	COG0571	ribonuclease III activity
C6P13_RS03510	COG1196	nuclear chromosome segregation
C6P13_RS03515	COG0552	protein localization to endoplasmic reticulum
C6P13_RS03520	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C6P13_RS03525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6P13_RS03540	COG0228	four-way junction DNA binding
C6P13_RS03550	COG0588	phosphoglycerate mutase activity
C6P13_RS03555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C6P13_RS03560	COG0336	Belongs to the RNA methyltransferase TrmD family
C6P13_RS03575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6P13_RS03580	COG1942	4-Oxalocrotonate Tautomerase
C6P13_RS03595	COG1428	Deoxynucleoside kinase
C6P13_RS03600	COG1970	mechanosensitive ion channel activity
C6P13_RS03605	COG0561	phosphatase activity
C6P13_RS03655	COG3853	Toxic anion resistance protein (TelA)
C6P13_RS03660	COG1393	Belongs to the ArsC family
C6P13_RS03665	COG4862	establishment of competence for transformation
C6P13_RS03670	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS03675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P13_RS03680	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6P13_RS03685	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS03690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P13_RS03700	COG1164	Oligoendopeptidase f
C6P13_RS03705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6P13_RS03720	COG1609	Transcriptional regulator
C6P13_RS03725	COG0006	proline dipeptidase activity
C6P13_RS03805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6P13_RS03810	COG3425	synthase
C6P13_RS03835	COG0124	histidyl-tRNA synthetase
C6P13_RS03840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C6P13_RS03850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6P13_RS03855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6P13_RS03860	COG1610	YqeY-like protein
C6P13_RS03865	COG1702	phosphate starvation-inducible protein PhoH
C6P13_RS03870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C6P13_RS03875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6P13_RS03880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6P13_RS03885	COG1381	Involved in DNA repair and RecF pathway recombination
C6P13_RS03895	COG0752	glycyl-tRNA synthetase alpha subunit
C6P13_RS03900	COG0751	glycine-tRNA ligase activity
C6P13_RS03935	COG2706	6-phosphogluconolactonase activity
C6P13_RS03940	COG0628	permease
C6P13_RS03950	COG1674	ftsk spoiiie
C6P13_RS03960	COG4152	abc transporter atp-binding protein
C6P13_RS03965	COG1668	transmembrane transport
C6P13_RS03980	COG0322	excinuclease ABC activity
C6P13_RS03990	COG1739	Uncharacterized protein family UPF0029
C6P13_RS04000	COG2814	Major facilitator Superfamily
C6P13_RS04005	COG0516	GMP reductase activity
C6P13_RS04005	COG0517	IMP dehydrogenase activity
C6P13_RS04010	COG0516	GMP reductase activity
C6P13_RS04010	COG0517	IMP dehydrogenase activity
C6P13_RS04015	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C6P13_RS04020	COG0632	four-way junction helicase activity
C6P13_RS04025	COG2255	four-way junction helicase activity
C6P13_RS04030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C6P13_RS04065	COG0343	queuine tRNA-ribosyltransferase activity
C6P13_RS04075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6P13_RS04080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C6P13_RS04085	COG0513	Belongs to the DEAD box helicase family
C6P13_RS04100	COG1929	Belongs to the glycerate kinase type-1 family
C6P13_RS04105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6P13_RS04120	COG3906	Belongs to the UPF0473 family
C6P13_RS04125	COG3906	Belongs to the UPF0473 family
C6P13_RS04130	COG1555	photosystem II stabilization
C6P13_RS04130	COG1596	polysaccharide export
C6P13_RS04135	COG0658	competence protein
C6P13_RS04135	COG2333	competence protein COMEC
C6P13_RS04140	COG1466	dna polymerase III delta subunit
C6P13_RS04145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C6P13_RS04150	COG0268	Binds directly to 16S ribosomal RNA
C6P13_RS04195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C6P13_RS04200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C6P13_RS04205	COG4166	transmembrane transport
C6P13_RS04225	COG1193	negative regulation of DNA recombination
C6P13_RS04240	COG1215	transferase activity, transferring glycosyl groups
C6P13_RS04250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6P13_RS04265	COG3118	belongs to the thioredoxin family
C6P13_RS04270	COG0110	maltose O-acetyltransferase activity
C6P13_RS04275	COG0737	Belongs to the 5'-nucleotidase family
C6P13_RS04280	COG3842	ATPase activity
C6P13_RS04285	COG1175	transmembrane transport
C6P13_RS04290	COG0395	ABC-type sugar transport system, permease component
C6P13_RS04305	COG0308	aminopeptidase N
C6P13_RS04335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6P13_RS04355	COG0681	Belongs to the peptidase S26 family
C6P13_RS04390	COG1621	beta-fructofuranosidase activity
C6P13_RS04395	COG1609	Transcriptional regulator
C6P13_RS04415	COG1063	alcohol dehydrogenase
C6P13_RS04420	COG0617	tRNA 3'-terminal CCA addition
C6P13_RS04420	COG1353	crispr-associated protein
C6P13_RS04425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C6P13_RS04480	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS04505	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C6P13_RS04510	COG0351	phosphomethylpyrimidine kinase
C6P13_RS04515	COG0352	thiamine-phosphate diphosphorylase activity
C6P13_RS04595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6P13_RS04600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C6P13_RS04615	COG2357	RelA SpoT domain protein
C6P13_RS04620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C6P13_RS04625	COG0564	pseudouridine synthase activity
C6P13_RS04630	COG2239	Acts as a magnesium transporter
C6P13_RS04645	COG1869	D-ribose catabolic process
C6P13_RS04650	COG0738	Major facilitator superfamily
C6P13_RS04690	COG2315	Protein conserved in bacteria
C6P13_RS04705	COG0488	(ABC) transporter
C6P13_RS04720	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P13_RS04745	COG0656	L-ascorbic acid biosynthetic process
C6P13_RS04750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6P13_RS04765	COG1846	Transcriptional regulator
C6P13_RS04770	COG0456	acetyltransferase
C6P13_RS04775	COG1309	transcriptional regulator
C6P13_RS04825	COG1737	Transcriptional regulator
C6P13_RS04830	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS04845	COG1940	carbohydrate kinase activity
C6P13_RS04850	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C6P13_RS04855	COG1349	DNA-binding transcription factor activity
C6P13_RS04860	COG1105	Belongs to the carbohydrate kinase PfkB family
C6P13_RS04865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P13_RS04865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P13_RS04865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P13_RS04870	COG2223	nitrite transmembrane transporter activity
C6P13_RS04880	COG0697	spore germination
C6P13_RS04890	COG4684	Psort location CytoplasmicMembrane, score
C6P13_RS04910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6P13_RS04920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C6P13_RS04925	COG0738	Major facilitator superfamily
C6P13_RS04930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C6P13_RS04935	COG0277	FAD linked oxidase domain protein
C6P13_RS04950	COG2814	Major facilitator Superfamily
C6P13_RS04955	COG1304	FMN binding
C6P13_RS04980	COG0779	Required for maturation of 30S ribosomal subunits
C6P13_RS04985	COG0195	Participates in both transcription termination and antitermination
C6P13_RS04990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C6P13_RS05000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C6P13_RS05005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C6P13_RS05010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6P13_RS05015	COG1252	NADH dehydrogenase
C6P13_RS05030	COG0196	riboflavin kinase activity
C6P13_RS05035	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C6P13_RS05040	COG3142	Participates in the control of copper homeostasis
C6P13_RS05055	COG2270	Major facilitator Superfamily
C6P13_RS05060	COG1307	EDD domain protein, DegV family
C6P13_RS05065	COG1307	EDD domain protein, DegV family
C6P13_RS05070	COG2755	lipolytic protein G-D-S-L family
C6P13_RS05080	COG4479	Belongs to the UPF0346 family
C6P13_RS05090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C6P13_RS05095	COG0758	DNA mediated transformation
C6P13_RS05100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6P13_RS05105	COG4974	Belongs to the 'phage' integrase family
C6P13_RS05115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C6P13_RS05120	COG0187	DNA topoisomerase II activity
C6P13_RS05140	COG4175	Glycine betaine
C6P13_RS05140	COG3448	diguanylate cyclase activity
C6P13_RS05150	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P13_RS05155	COG1464	Belongs to the NlpA lipoprotein family
C6P13_RS05160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6P13_RS05170	COG1011	Hydrolase
C6P13_RS05185	COG5503	Protein of unknown function (DUF1447)
C6P13_RS05200	COG0242	peptide deformylase activity
C6P13_RS05205	COG4476	Belongs to the UPF0223 family
C6P13_RS05210	COG0483	inositol monophosphate 1-phosphatase activity
C6P13_RS05215	COG1217	gtp-binding protein TYPA
C6P13_RS05220	COG0772	Belongs to the SEDS family
C6P13_RS05225	COG4471	UPF0298 protein
C6P13_RS05230	COG0742	ribosomal rna small subunit methyltransferase
C6P13_RS05235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C6P13_RS05240	COG3480	Lon protease (S16) C-terminal proteolytic domain
C6P13_RS05245	COG0105	UTP biosynthetic process
C6P13_RS05250	COG0477	Major facilitator Superfamily
C6P13_RS05255	COG0358	DNA primase activity
C6P13_RS05260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6P13_RS05285	COG0745	RESPONSE REGULATOR receiver
C6P13_RS05290	COG5002	protein histidine kinase activity
C6P13_RS05295	COG0572	uridine kinase
C6P13_RS05300	COG1363	Peptidase, m42
C6P13_RS05305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6P13_RS05315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6P13_RS05325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6P13_RS05325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6P13_RS05330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C6P13_RS05345	COG1484	DNA-dependent DNA replication
C6P13_RS05360	COG0745	RESPONSE REGULATOR receiver
C6P13_RS05365	COG5002	protein histidine kinase activity
C6P13_RS05385	COG1942	4-Oxalocrotonate Tautomerase
C6P13_RS05400	COG0706	membrane insertase activity
C6P13_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
C6P13_RS05410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6P13_RS05420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6P13_RS05435	COG0577	efflux transmembrane transporter activity
C6P13_RS05440	COG1136	(ABC) transporter
C6P13_RS05445	COG2076	Multidrug Resistance protein
C6P13_RS05450	COG2076	Multidrug Resistance protein
C6P13_RS05460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P13_RS05475	COG0281	malic enzyme
C6P13_RS05480	COG0583	DNA-binding transcription factor activity
C6P13_RS05485	COG4221	oxidoreductase activity
C6P13_RS05490	COG0531	amino acid
C6P13_RS05500	COG4708	membrane
C6P13_RS05520	COG0481	GTPase activity
C6P13_RS05530	COG0531	amino acid
C6P13_RS05550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6P13_RS05555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P13_RS05560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C6P13_RS05565	COG1914	H( )-stimulated, divalent metal cation uptake system
C6P13_RS05655	COG1719	4-vinyl reductase, 4VR
C6P13_RS05660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C6P13_RS05670	COG1131	(ABC) transporter
C6P13_RS05675	COG0537	adenosine 5'-monophosphoramidase activity
C6P13_RS05685	COG0363	glucosamine-6-phosphate deaminase activity
C6P13_RS05690	COG3104	oligopeptide transport
C6P13_RS05715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6P13_RS05720	COG0363	glucosamine-6-phosphate deaminase activity
C6P13_RS05725	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS05735	COG2272	Belongs to the type-B carboxylesterase lipase family
C6P13_RS05740	COG0825	malonyl-CoA metabolic process
C6P13_RS05745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C6P13_RS05750	COG0439	Biotin carboxylase
C6P13_RS05760	COG0556	nucleotide-excision repair
C6P13_RS05775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C6P13_RS05785	COG0116	Belongs to the methyltransferase superfamily
C6P13_RS05795	COG3599	regulation of cell shape
C6P13_RS05800	COG4474	Belongs to the UPF0398 family
C6P13_RS05805	COG3331	DNA recombination
C6P13_RS05815	COG3935	DnaD domain protein
C6P13_RS05980	COG0629	single-stranded DNA binding
C6P13_RS06040	COG1396	sequence-specific DNA binding
C6P13_RS06070	COG0582	viral genome integration into host DNA
C6P13_RS06075	COG0017	Asparaginyl-tRNA synthetase
C6P13_RS06080	COG5353	protein conserved in bacteria
C6P13_RS06085	COG1199	ATP-dependent helicase activity
C6P13_RS06085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P13_RS06105	COG1304	FMN binding
C6P13_RS06120	COG3620	sequence-specific DNA binding
C6P13_RS06125	COG1695	Transcriptional regulator
C6P13_RS06145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C6P13_RS06150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C6P13_RS06155	COG2211	Major facilitator Superfamily
C6P13_RS06155	COG2190	(PTS) system
C6P13_RS06165	COG0028	Belongs to the TPP enzyme family
C6P13_RS06170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C6P13_RS06175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C6P13_RS06180	COG1464	Belongs to the NlpA lipoprotein family
C6P13_RS06190	COG2357	RelA SpoT domain protein
C6P13_RS06215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C6P13_RS06225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6P13_RS06235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6P13_RS06240	COG2384	SAM-dependent methyltransferase
C6P13_RS06245	COG0071	Belongs to the small heat shock protein (HSP20) family
C6P13_RS06280	COG0457	Tetratricopeptide repeat
C6P13_RS06310	COG0419	ATPase involved in DNA repair
C6P13_RS06315	COG0420	3'-5' exonuclease activity
C6P13_RS06325	COG2807	transmembrane transport
C6P13_RS06330	COG4720	Psort location CytoplasmicMembrane, score
C6P13_RS06345	COG1160	GTP binding
C6P13_RS06350	COG0539	negative regulation of cytoplasmic translation
C6P13_RS06355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C6P13_RS06365	COG0514	ATP-dependent DNA helicase (RecQ)
C6P13_RS06375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C6P13_RS06390	COG1187	pseudouridine synthase activity
C6P13_RS06395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6P13_RS06400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6P13_RS06415	COG2996	Protein conserved in bacteria
C6P13_RS06435	COG0475	glutathione-regulated potassium exporter activity
C6P13_RS06445	COG1490	D-aminoacyl-tRNA deacylase activity
C6P13_RS06450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6P13_RS06455	COG0587	DNA-directed DNA polymerase activity
C6P13_RS06470	COG0488	(ABC) transporter
C6P13_RS06475	COG0617	tRNA 3'-terminal CCA addition
C6P13_RS06485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6P13_RS06490	COG0004	ammonium transporteR
C6P13_RS06495	COG1940	carbohydrate kinase activity
C6P13_RS06520	COG0233	cytoplasmic translational termination
C6P13_RS06530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C6P13_RS06550	COG2827	Endonuclease containing a URI domain
C6P13_RS06555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C6P13_RS06560	COG0204	Acyl-transferase
C6P13_RS06565	COG0366	Alpha amylase catalytic
C6P13_RS06565	COG5263	repeat protein
C6P13_RS06570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C6P13_RS06580	COG3763	UPF0154 protein
C6P13_RS06585	COG4224	UPF0291 protein
C6P13_RS06590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6P13_RS06600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6P13_RS06600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C6P13_RS06605	COG1234	tRNA 3'-trailer cleavage
C6P13_RS06625	COG0484	heat shock protein binding
C6P13_RS06630	COG0443	Heat shock 70 kDa protein
C6P13_RS06640	COG1420	regulation of RNA biosynthetic process
C6P13_RS06650	COG1682	transport, permease protein
C6P13_RS06655	COG1134	teichoic acid transport
C6P13_RS06655	COG1388	LysM domain
C6P13_RS06665	COG1216	Glycosyl transferase, family 2
C6P13_RS06670	COG0562	UDP-galactopyranose mutase
C6P13_RS06680	COG0463	Glycosyl transferase, family 2
C6P13_RS06690	COG0024	Methionine aminopeptidase
C6P13_RS06715	COG0463	Glycosyl transferase, family 2
C6P13_RS06730	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6P13_RS06730	COG1388	LysM domain
C6P13_RS06745	COG3835	regulator
C6P13_RS06765	COG2309	aminopeptidase activity
C6P13_RS06780	COG0564	pseudouridine synthase activity
C6P13_RS06785	COG1278	Cold shock
C6P13_RS06800	COG0741	lytic transglycosylase activity
C6P13_RS06810	COG3973	AAA domain
C6P13_RS06820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C6P13_RS06825	COG1546	Belongs to the CinA family
C6P13_RS06825	COG1058	Belongs to the CinA family
C6P13_RS06830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6P13_RS06835	COG1426	Protein conserved in bacteria
C6P13_RS06840	COG0612	Peptidase, M16
C6P13_RS06845	COG0612	Peptidase, M16
C6P13_RS06865	COG1070	Carbohydrate kinase
C6P13_RS06890	COG4717	serine-type aminopeptidase activity
C6P13_RS06895	COG0420	3'-5' exonuclease activity
C6P13_RS06900	COG3679	Belongs to the UPF0342 family
C6P13_RS06905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6P13_RS06910	COG1438	arginine binding
C6P13_RS06915	COG0306	phosphate transporter
C6P13_RS06930	COG0519	Catalyzes the synthesis of GMP from XMP
C6P13_RS06935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6P13_RS06940	COG4608	Belongs to the ABC transporter superfamily
C6P13_RS06945	COG0444	Belongs to the ABC transporter superfamily
C6P13_RS06950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P13_RS06955	COG0601	transmembrane transport
C6P13_RS06960	COG0747	negative chemotaxis
C6P13_RS06965	COG0018	arginyl-trna synthetase
C6P13_RS06980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C6P13_RS06990	COG1121	(ABC) transporter
C6P13_RS06995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P13_RS07005	COG2315	Protein conserved in bacteria
C6P13_RS07015	COG1597	lipid kinase activity
C6P13_RS07020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6P13_RS07025	COG0154	amidase activity
C6P13_RS07030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6P13_RS07035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6P13_RS07035	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C6P13_RS07070	COG1914	H( )-stimulated, divalent metal cation uptake system
C6P13_RS07075	COG0456	acetyltransferase
C6P13_RS07095	COG0667	Aldo Keto reductase
C6P13_RS07100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6P13_RS07105	COG0167	dihydroorotate dehydrogenase activity
C6P13_RS07115	COG1122	ATPase activity
C6P13_RS07125	COG2115	Belongs to the xylose isomerase family
C6P13_RS07130	COG0710	3-dehydroquinate dehydratase activity
C6P13_RS07135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C6P13_RS07140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6P13_RS07145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C6P13_RS07150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C6P13_RS07155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C6P13_RS07160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6P13_RS07180	COG0438	transferase activity, transferring glycosyl groups
C6P13_RS07190	COG4684	Psort location CytoplasmicMembrane, score
C6P13_RS07195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P13_RS07215	COG1609	Transcriptional regulator
C6P13_RS07220	COG1136	(ABC) transporter
C6P13_RS07220	COG0577	efflux transmembrane transporter activity
C6P13_RS07225	COG1136	(ABC) transporter
C6P13_RS07240	COG1131	(ABC) transporter
C6P13_RS07245	COG2188	Transcriptional regulator
C6P13_RS07255	COG0436	Aminotransferase
C6P13_RS07265	COG0596	Alpha beta hydrolase
C6P13_RS07270	COG4166	transmembrane transport
C6P13_RS07280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6P13_RS07285	COG0436	Aminotransferase
C6P13_RS07290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C6P13_RS07295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6P13_RS07300	COG1473	amidohydrolase
C6P13_RS07305	COG2171	N-acyltransferase activity
C6P13_RS07315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6P13_RS07320	COG0527	aspartate kinase activity
C6P13_RS07330	COG1609	Transcriptional regulator
C6P13_RS07335	COG0083	homoserine kinase activity
C6P13_RS07350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P13_RS07350	COG1321	iron dependent repressor
C6P13_RS07355	COG3764	Sortase (surface protein transpeptidase)
C6P13_RS07360	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C6P13_RS07365	COG0513	Belongs to the DEAD box helicase family
C6P13_RS07370	COG0673	inositol 2-dehydrogenase activity
C6P13_RS07375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6P13_RS07380	COG0501	Belongs to the peptidase M48B family
C6P13_RS07385	COG1704	LemA family
C6P13_RS07390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6P13_RS07395	COG4115	mRNA cleavage
C6P13_RS07400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6P13_RS07415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C6P13_RS07420	COG0439	Biotin carboxylase
C6P13_RS07435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6P13_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
C6P13_RS07445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6P13_RS07450	COG2070	2-Nitropropane dioxygenase
C6P13_RS07455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6P13_RS07460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6P13_RS07465	COG1846	Transcriptional regulator
C6P13_RS07470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C6P13_RS07480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6P13_RS07485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6P13_RS07495	COG0505	Belongs to the CarA family
C6P13_RS07505	COG0564	pseudouridine synthase activity
C6P13_RS07515	COG0328	RNA-DNA hybrid ribonuclease activity
C6P13_RS07520	COG1757	Na H antiporter
C6P13_RS07555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C6P13_RS07560	COG1113	amino acid transport
C6P13_RS07575	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
C6P13_RS07595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6P13_RS07600	COG1132	(ABC) transporter
C6P13_RS07610	COG0583	DNA-binding transcription factor activity
C6P13_RS07615	COG1811	Na channel or pump
C6P13_RS07620	COG0126	phosphoglycerate kinase activity
C6P13_RS07685	COG1027	Aspartate ammonia-lyase
C6P13_RS07755	COG1368	sulfuric ester hydrolase activity
C6P13_RS07770	COG0438	transferase activity, transferring glycosyl groups
C6P13_RS07775	COG0438	transferase activity, transferring glycosyl groups
C6P13_RS07780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C6P13_RS07785	COG0284	orotidine-5'-phosphate decarboxylase activity
C6P13_RS07790	COG0167	dihydroorotate dehydrogenase activity
C6P13_RS07795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6P13_RS07800	COG0505	Belongs to the CarA family
C6P13_RS07810	COG0540	Belongs to the ATCase OTCase family
C6P13_RS07835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6P13_RS07840	COG4856	YbbR-like protein
C6P13_RS07855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6P13_RS07865	COG0456	acetyltransferase
C6P13_RS07870	COG0802	atpase or kinase
C6P13_RS07875	COG0280	phosphate acetyltransferase
C6P13_RS07890	COG2076	Multidrug Resistance protein
C6P13_RS07895	COG2076	Multidrug Resistance protein
C6P13_RS07900	COG1126	abc transporter atp-binding protein
C6P13_RS07905	COG0765	amino acid transport
C6P13_RS07915	COG0557	exoribonuclease II activity
C6P13_RS07925	COG2814	Major facilitator Superfamily
C6P13_RS07945	COG0149	triose-phosphate isomerase activity
C6P13_RS07950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6P13_RS07955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P13_RS07965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6P13_RS07970	COG0492	ferredoxin-NADP+ reductase activity
C6P13_RS07990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6P13_RS07995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C6P13_RS08000	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C6P13_RS08015	COG0589	response to stress
C6P13_RS08025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6P13_RS08035	COG1177	transmembrane transport
C6P13_RS08045	COG3842	ATPase activity
C6P13_RS08055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C6P13_RS08060	COG0049	tRNA binding
C6P13_RS08065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C6P13_RS08080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C6P13_RS08085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C6P13_RS08090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C6P13_RS08100	COG1302	Protein conserved in bacteria
C6P13_RS08105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C6P13_RS08115	COG2017	converts alpha-aldose to the beta-anomer
C6P13_RS08125	COG4975	Glucose uptake
C6P13_RS08130	COG5002	protein histidine kinase activity
C6P13_RS08130	COG3850	Histidine kinase
C6P13_RS08135	COG0745	RESPONSE REGULATOR receiver
C6P13_RS08140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6P13_RS08145	COG0402	S-adenosylhomocysteine deaminase activity
C6P13_RS08160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P13_RS08175	COG0668	transmembrane transport
C6P13_RS08180	COG0516	GMP reductase activity
C6P13_RS08185	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P13_RS08265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C6P13_RS08270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6P13_RS08270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6P13_RS08280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6P13_RS08280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6P13_RS08300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6P13_RS08350	COG1266	CAAX protease self-immunity
C6P13_RS08360	COG4166	transmembrane transport
C6P13_RS08380	COG0561	phosphatase activity
C6P13_RS08420	COG0577	efflux transmembrane transporter activity
C6P13_RS08425	COG1136	(ABC) transporter
C6P13_RS08435	COG0436	Aminotransferase
C6P13_RS08440	COG3759	membrane
C6P13_RS08445	COG2723	6-phospho-beta-galactosidase activity
C6P13_RS08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P13_RS08450	COG1263	PTS System
C6P13_RS08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P13_RS08480	COG1609	Transcriptional regulator
C6P13_RS08510	COG2814	Major facilitator Superfamily
C6P13_RS08515	COG2217	Heavy metal translocating P-type atpase
C6P13_RS08525	COG0431	NADPH-dependent FMN reductase
C6P13_RS08540	COG2183	response to ionizing radiation
C6P13_RS08550	COG2873	o-acetylhomoserine
C6P13_RS08555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6P13_RS08565	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C6P13_RS08610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P13_RS08630	COG1131	(ABC) transporter
C6P13_RS08680	COG2176	DNA-directed DNA polymerase activity
C6P13_RS08685	COG0442	prolyl-tRNA aminoacylation
C6P13_RS08690	COG0750	zinc metalloprotease
C6P13_RS08695	COG4589	Belongs to the CDS family
C6P13_RS08700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6P13_RS08705	COG0561	phosphatase activity
C6P13_RS08750	COG0656	L-ascorbic acid biosynthetic process
C6P13_RS08760	COG2814	Major facilitator Superfamily
C6P13_RS08780	COG1307	EDD domain protein, DegV family
C6P13_RS08805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6P13_RS08810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C6P13_RS08820	COG2252	PERMEase
C6P13_RS08825	COG0352	thiamine-phosphate diphosphorylase activity
C6P13_RS08835	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C6P13_RS08850	COG3594	Acyltransferase
C6P13_RS08855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C6P13_RS08865	COG2188	Transcriptional regulator
C6P13_RS08875	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6P13_RS08880	COG1136	(ABC) transporter
C6P13_RS08880	COG0577	efflux transmembrane transporter activity
C6P13_RS08890	COG0561	phosphatase activity
C6P13_RS08895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6P13_RS08900	COG0561	phosphatase activity
C6P13_RS08915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6P13_RS08920	COG0772	Belongs to the SEDS family
C6P13_RS08930	COG1077	Cell shape determining protein MreB Mrl
C6P13_RS08935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6P13_RS08945	COG1079	Belongs to the binding-protein-dependent transport system permease family
C6P13_RS08950	COG4603	Belongs to the binding-protein-dependent transport system permease family
C6P13_RS08955	COG3845	ABC transporter
C6P13_RS08960	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS08965	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS08970	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS08975	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P13_RS08985	COG0640	Transcriptional regulator
C6P13_RS08990	COG0628	permease
C6P13_RS08995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6P13_RS09010	COG0588	phosphoglycerate mutase activity
C6P13_RS09015	COG0492	ferredoxin-NADP+ reductase activity
C6P13_RS09030	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS09035	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS09045	COG2832	Protein of unknown function (DUF454)
C6P13_RS09080	COG2814	Major facilitator Superfamily
C6P13_RS09085	COG0305	Participates in initiation and elongation during chromosome replication
C6P13_RS09090	COG0359	binds to the 23S rRNA
C6P13_RS09100	COG4608	Belongs to the ABC transporter superfamily
C6P13_RS09105	COG0444	Belongs to the ABC transporter superfamily
C6P13_RS09110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P13_RS09115	COG0601	transmembrane transport
C6P13_RS09120	COG4166	transmembrane transport
C6P13_RS09125	COG1957	nucleoside hydrolase
C6P13_RS09135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6P13_RS09170	COG1609	Transcriptional regulator
C6P13_RS09175	COG2814	Major facilitator Superfamily
C6P13_RS09185	COG0765	amino acid transport
C6P13_RS09190	COG0765	amino acid transport
C6P13_RS09195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P13_RS09200	COG1126	abc transporter atp-binding protein
C6P13_RS09215	COG0194	GDP metabolic process
C6P13_RS09220	COG1268	BioY protein
C6P13_RS09250	COG2211	Major facilitator Superfamily
C6P13_RS09255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6P13_RS09260	COG0673	inositol 2-dehydrogenase activity
C6P13_RS09275	COG3973	AAA domain
C6P13_RS09285	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6P13_RS09290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6P13_RS09300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C6P13_RS09305	COG0504	CTP synthase activity
C6P13_RS09325	COG3343	RNA polymerase activity
C6P13_RS09330	COG0561	phosphatase activity
C6P13_RS09335	COG1078	dGTPase activity
C6P13_RS09345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6P13_RS09350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6P13_RS09365	COG5002	protein histidine kinase activity
C6P13_RS09370	COG0745	RESPONSE REGULATOR receiver
C6P13_RS09400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6P13_RS09405	COG0629	single-stranded DNA binding
C6P13_RS09410	COG0360	Binds together with S18 to 16S ribosomal RNA
C6P13_RS09420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6P13_RS09430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6P13_RS09435	COG1051	belongs to the nudix hydrolase family
C6P13_RS09445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6P13_RS09450	COG2814	Major facilitator Superfamily
C6P13_RS09455	COG1064	alcohol dehydrogenase
C6P13_RS09460	COG1074	ATP-dependent DNA helicase activity
C6P13_RS09465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C6P13_RS09470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6P13_RS09475	COG0531	amino acid
C6P13_RS09480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6P13_RS09490	COG1902	pentaerythritol trinitrate reductase activity
C6P13_RS09495	COG0626	cystathionine gamma-synthase activity
C6P13_RS09505	COG2244	polysaccharide biosynthetic process
C6P13_RS09515	COG0438	transferase activity, transferring glycosyl groups
C6P13_RS09520	COG0495	leucyl-tRNA aminoacylation
C6P13_RS09525	COG0671	phosphoesterase, PA-phosphatase related
C6P13_RS09535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6P13_RS09555	COG2246	polysaccharide biosynthetic process
C6P13_RS09560	COG1744	ABC transporter substrate-binding protein PnrA-like
C6P13_RS09585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C6P13_RS09595	COG0024	Methionine aminopeptidase
C6P13_RS09605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6P13_RS09610	COG0737	Belongs to the 5'-nucleotidase family
C6P13_RS09615	COG3639	organic phosphonate transmembrane transporter activity
C6P13_RS09625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C6P13_RS09645	COG0604	alcohol dehydrogenase
C6P13_RS09650	COG1435	thymidine kinase activity
C6P13_RS09655	COG1316	TRANSCRIPTIONal
C6P13_RS09665	COG2205	protein histidine kinase activity
C6P13_RS09670	COG0745	RESPONSE REGULATOR receiver
C6P13_RS09690	COG1914	H( )-stimulated, divalent metal cation uptake system
C6P13_RS09755	COG0438	transferase activity, transferring glycosyl groups
C6P13_RS09760	COG2084	Dehydrogenase
C6P13_RS09770	COG1620	l-lactate permease
C6P13_RS09775	COG4989	oxidoreductase activity
C6P13_RS09780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6P13_RS09785	COG2233	PERMEase
C6P13_RS09800	COG1956	GAF domain-containing protein
C6P13_RS09810	COG1216	Glycosyl transferase, family 2
C6P13_RS09825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6P13_RS09850	COG0531	amino acid
C6P13_RS09855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6P13_RS09860	COG2235	arginine
C6P13_RS09865	COG2910	NAD(P)H-binding
C6P13_RS09885	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C6P13_RS09890	COG1737	Transcriptional regulator
C6P13_RS09900	COG0656	L-ascorbic acid biosynthetic process
C6P13_RS09905	COG2261	transglycosylase associated protein
C6P13_RS09970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6P13_RS09975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C6P13_RS09985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6P13_RS10000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6P13_RS10005	COG2244	polysaccharide biosynthetic process
C6P13_RS10010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6P13_RS10015	COG0193	aminoacyl-tRNA hydrolase activity
C6P13_RS10025	COG0366	Alpha amylase catalytic
C6P13_RS10025	COG3103	Sh3 type 3 domain protein
C6P13_RS10030	COG0058	SHG alpha-glucan phosphorylase activity
C6P13_RS10040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C6P13_RS10050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C6P13_RS10055	COG1511	domain protein
C6P13_RS10060	COG1309	transcriptional regulator
C6P13_RS10075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P13_RS10080	COG0477	Major facilitator Superfamily
C6P13_RS10095	COG2115	Belongs to the xylose isomerase family
C6P13_RS10100	COG1846	Transcriptional regulator
C6P13_RS10100	COG1940	carbohydrate kinase activity
C6P13_RS10105	COG2211	Major facilitator Superfamily
C6P13_RS10110	COG3507	Belongs to the glycosyl hydrolase 43 family
C6P13_RS10135	COG1968	undecaprenyl-diphosphatase activity
C6P13_RS10150	COG1695	Transcriptional regulator
C6P13_RS10155	COG1983	PspC domain protein
C6P13_RS10160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6P13_RS10165	COG1316	TRANSCRIPTIONal
C6P13_RS10175	COG2131	deaminase
C6P13_RS10180	COG4466	Protein conserved in bacteria
C6P13_RS10185	COG1253	flavin adenine dinucleotide binding
C6P13_RS10190	COG1253	flavin adenine dinucleotide binding
C6P13_RS10195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C6P13_RS10200	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C6P13_RS10205	COG0084	hydrolase, TatD family'
C6P13_RS10215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6P13_RS10215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6P13_RS10245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6P13_RS10265	COG1368	sulfuric ester hydrolase activity
C6P13_RS10285	COG0187	DNA topoisomerase II activity
C6P13_RS10290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C6P13_RS10295	COG2501	S4 domain
C6P13_RS10300	COG0592	DNA-directed DNA polymerase activity
C6P13_RS10315	COG2261	transglycosylase associated protein