locus-tag	class	description
EQG49_RS00005	COG4894	glucomannan catabolic process
EQG49_RS00025	COG1227	inorganic diphosphatase activity
EQG49_RS00030	COG0583	DNA-binding transcription factor activity
EQG49_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQG49_RS00040	COG0187	DNA topoisomerase II activity
EQG49_RS00050	COG0791	NLP P60 protein
EQG49_RS00055	COG1523	belongs to the glycosyl hydrolase 13 family
EQG49_RS00065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQG49_RS00070	COG0358	DNA primase activity
EQG49_RS00085	COG1192	Involved in chromosome partitioning
EQG49_RS00215	COG2856	Zn peptidase
EQG49_RS00230	COG0791	NLP P60 protein
EQG49_RS00230	COG1388	LysM domain
EQG49_RS00265	COG0542	response to heat
EQG49_RS00500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQG49_RS00530	COG0582	viral genome integration into host DNA
EQG49_RS00550	COG3764	Sortase (surface protein transpeptidase)
EQG49_RS00575	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EQG49_RS00590	COG1187	pseudouridine synthase activity
EQG49_RS00595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQG49_RS00600	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQG49_RS00615	COG2996	Protein conserved in bacteria
EQG49_RS00620	COG1272	protein, Hemolysin III
EQG49_RS00630	COG1942	4-Oxalocrotonate Tautomerase
EQG49_RS00640	COG0789	Transcriptional regulator
EQG49_RS00645	COG0477	Major facilitator Superfamily
EQG49_RS00655	COG1131	(ABC) transporter
EQG49_RS00720	COG1104	cysteine desulfurase activity
EQG49_RS00725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQG49_RS00735	COG0494	nUDIX hydrolase
EQG49_RS00745	COG0482	sulfurtransferase activity
EQG49_RS00760	COG0626	cystathionine gamma-synthase activity
EQG49_RS00790	COG1304	FMN binding
EQG49_RS00795	COG0584	glycerophosphoryl diester phosphodiesterase
EQG49_RS00800	COG3842	ATPase activity
EQG49_RS00810	COG0395	ABC-type sugar transport system, permease component
EQG49_RS00815	COG1653	transport
EQG49_RS00835	COG2801	Transposase and inactivated derivatives
EQG49_RS00840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQG49_RS00845	COG1132	(ABC) transporter
EQG49_RS00850	COG1136	(ABC) transporter
EQG49_RS00850	COG0577	efflux transmembrane transporter activity
EQG49_RS00870	COG1979	alcohol dehydrogenase
EQG49_RS00880	COG1132	(ABC) transporter
EQG49_RS00885	COG1132	(ABC) transporter
EQG49_RS00895	COG3425	synthase
EQG49_RS00910	COG1307	EDD domain protein, DegV family
EQG49_RS00925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQG49_RS00950	COG0765	amino acid transport
EQG49_RS00980	COG0582	viral genome integration into host DNA
EQG49_RS00985	COG0572	uridine kinase
EQG49_RS01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQG49_RS01040	COG1609	Transcriptional regulator
EQG49_RS01045	COG0572	uridine kinase
EQG49_RS01060	COG2610	gluconate transmembrane transporter activity
EQG49_RS01065	COG1511	domain protein
EQG49_RS01075	COG0105	UTP biosynthetic process
EQG49_RS01095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQG49_RS01135	COG0825	malonyl-CoA metabolic process
EQG49_RS01140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQG49_RS01145	COG0439	Biotin carboxylase
EQG49_RS01160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQG49_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
EQG49_RS01170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQG49_RS01185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQG49_RS01190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQG49_RS01205	COG0386	Belongs to the glutathione peroxidase family
EQG49_RS01210	COG2814	Major facilitator Superfamily
EQG49_RS01220	COG1131	(ABC) transporter
EQG49_RS01235	COG2801	Transposase and inactivated derivatives
EQG49_RS01270	COG4684	Psort location CytoplasmicMembrane, score
EQG49_RS01275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQG49_RS01280	COG0438	transferase activity, transferring glycosyl groups
EQG49_RS01290	COG0366	Alpha amylase catalytic
EQG49_RS01295	COG2188	Transcriptional regulator
EQG49_RS01305	COG2190	(PTS) system
EQG49_RS01305	COG1263	PTS System
EQG49_RS01305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQG49_RS01310	COG0671	phosphoesterase, PA-phosphatase related
EQG49_RS01350	COG1408	metallophosphoesterase
EQG49_RS01355	COG0183	Belongs to the thiolase family
EQG49_RS01365	COG0025	NhaP-type Na H and K H
EQG49_RS01380	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS01400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EQG49_RS01400	COG2755	lipolytic protein G-D-S-L family
EQG49_RS01430	COG0300	oxidoreductase activity
EQG49_RS01440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQG49_RS01460	COG1929	Belongs to the glycerate kinase type-1 family
EQG49_RS01465	COG2610	gluconate transmembrane transporter activity
EQG49_RS01475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQG49_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
EQG49_RS01520	COG1881	PFAM PEBP family protein
EQG49_RS01530	COG2226	methyltransferase
EQG49_RS01575	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQG49_RS01580	COG0302	gtp cyclohydrolase
EQG49_RS01585	COG0302	gtp cyclohydrolase
EQG49_RS01585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQG49_RS01610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQG49_RS01670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQG49_RS01675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQG49_RS01680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQG49_RS01685	COG1116	anion transmembrane transporter activity
EQG49_RS01720	COG4862	establishment of competence for transformation
EQG49_RS01725	COG1393	Belongs to the ArsC family
EQG49_RS01730	COG1234	tRNA 3'-trailer cleavage
EQG49_RS01740	COG0442	prolyl-tRNA aminoacylation
EQG49_RS01745	COG0750	zinc metalloprotease
EQG49_RS01750	COG4589	Belongs to the CDS family
EQG49_RS01755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQG49_RS01760	COG0515	serine threonine protein kinase
EQG49_RS01760	COG2815	serine threonine protein kinase
EQG49_RS01785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQG49_RS01785	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EQG49_RS01790	COG0561	phosphatase activity
EQG49_RS01795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQG49_RS01830	COG1758	RNA polymerase activity
EQG49_RS01835	COG0194	GDP metabolic process
EQG49_RS01840	COG0237	dephospho-CoA kinase activity
EQG49_RS01845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQG49_RS01850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQG49_RS01850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQG49_RS01855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQG49_RS01855	COG1199	ATP-dependent helicase activity
EQG49_RS01860	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EQG49_RS01875	COG1304	FMN binding
EQG49_RS01880	COG0716	FMN binding
EQG49_RS01900	COG2239	Acts as a magnesium transporter
EQG49_RS01905	COG0564	pseudouridine synthase activity
EQG49_RS01910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQG49_RS01915	COG2357	RelA SpoT domain protein
EQG49_RS01925	COG2252	PERMEase
EQG49_RS01935	COG0647	UMP catabolic process
EQG49_RS01940	COG4470	Protein conserved in bacteria
EQG49_RS01945	COG0737	Belongs to the 5'-nucleotidase family
EQG49_RS01955	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQG49_RS01955	COG3409	Peptidoglycan-binding domain 1 protein
EQG49_RS01965	COG1396	sequence-specific DNA binding
EQG49_RS01990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQG49_RS01995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQG49_RS02000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQG49_RS02005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQG49_RS02020	COG0392	lysyltransferase activity
EQG49_RS02020	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQG49_RS02030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQG49_RS02035	COG1940	carbohydrate kinase activity
EQG49_RS02045	COG3682	Transcriptional regulator
EQG49_RS02055	COG0528	UMP kinase activity
EQG49_RS02060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQG49_RS02065	COG0052	Belongs to the universal ribosomal protein uS2 family
EQG49_RS02070	COG2827	Endonuclease containing a URI domain
EQG49_RS02075	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQG49_RS02080	COG0204	Acyl-transferase
EQG49_RS02085	COG3763	UPF0154 protein
EQG49_RS02090	COG4224	UPF0291 protein
EQG49_RS02095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQG49_RS02105	COG3906	Belongs to the UPF0473 family
EQG49_RS02110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EQG49_RS02120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQG49_RS02135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQG49_RS02140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQG49_RS02150	COG1253	flavin adenine dinucleotide binding
EQG49_RS02160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQG49_RS02165	COG0768	penicillin binding
EQG49_RS02175	COG0300	oxidoreductase activity
EQG49_RS02185	COG2176	DNA-directed DNA polymerase activity
EQG49_RS02200	COG0827	DNA restriction-modification system
EQG49_RS02225	COG4537	Required for transformation and DNA binding
EQG49_RS02430	COG1396	sequence-specific DNA binding
EQG49_RS02460	COG0629	single-stranded DNA binding
EQG49_RS02555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQG49_RS02580	COG0116	Belongs to the methyltransferase superfamily
EQG49_RS02590	COG3599	regulation of cell shape
EQG49_RS02595	COG4474	Belongs to the UPF0398 family
EQG49_RS02600	COG3331	DNA recombination
EQG49_RS02605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQG49_RS02610	COG0366	Alpha amylase catalytic
EQG49_RS02615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQG49_RS02620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQG49_RS02620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQG49_RS02625	COG1234	tRNA 3'-trailer cleavage
EQG49_RS02640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQG49_RS02645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQG49_RS02650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQG49_RS02655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQG49_RS02670	COG0275	rRNA processing
EQG49_RS02675	COG2001	Belongs to the MraZ family
EQG49_RS02700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQG49_RS02705	COG1399	metal-binding, possibly nucleic acid-binding protein
EQG49_RS02710	COG1323	Belongs to the UPF0348 family
EQG49_RS02815	COG0861	Integral membrane protein TerC family
EQG49_RS02820	COG0670	Belongs to the BI1 family
EQG49_RS02825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQG49_RS02835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQG49_RS02840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQG49_RS02845	COG1363	Peptidase, m42
EQG49_RS02850	COG5584	Small secreted protein
EQG49_RS02855	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQG49_RS02860	COG4717	serine-type aminopeptidase activity
EQG49_RS02865	COG0420	3'-5' exonuclease activity
EQG49_RS02870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQG49_RS02875	COG1122	ATPase activity
EQG49_RS02880	COG4720	Psort location CytoplasmicMembrane, score
EQG49_RS02895	COG2801	Transposase and inactivated derivatives
EQG49_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQG49_RS02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS02925	COG1126	abc transporter atp-binding protein
EQG49_RS02930	COG0765	amino acid transport
EQG49_RS02940	COG1792	Involved in formation and maintenance of cell shape
EQG49_RS02945	COG1077	Cell shape determining protein MreB Mrl
EQG49_RS02960	COG0151	Belongs to the GarS family
EQG49_RS02965	COG0138	bifunctional purine biosynthesis protein purh
EQG49_RS02970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQG49_RS02985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQG49_RS02990	COG0047	phosphoribosylformylglycinamidine synthase activity
EQG49_RS02995	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQG49_RS03000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQG49_RS03005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQG49_RS03010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQG49_RS03040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQG49_RS03045	COG0557	exoribonuclease II activity
EQG49_RS03070	COG2818	Glycosylase
EQG49_RS03085	COG0525	valine-tRNA ligase activity
EQG49_RS03090	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQG49_RS03105	COG1674	ftsk spoiiie
EQG49_RS03125	COG0628	permease
EQG49_RS03130	COG2706	6-phosphogluconolactonase activity
EQG49_RS03135	COG3142	Participates in the control of copper homeostasis
EQG49_RS03185	COG1120	ATPase activity
EQG49_RS03215	COG0028	Belongs to the TPP enzyme family
EQG49_RS03230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQG49_RS03255	COG0582	viral genome integration into host DNA
EQG49_RS03260	COG0301	tRNA thio-modification
EQG49_RS03265	COG1104	cysteine desulfurase activity
EQG49_RS03280	COG0308	aminopeptidase N
EQG49_RS03290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQG49_RS03295	COG1597	lipid kinase activity
EQG49_RS03300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQG49_RS03305	COG0154	amidase activity
EQG49_RS03310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQG49_RS03360	COG0285	dihydrofolate synthase activity
EQG49_RS03370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQG49_RS03380	COG1131	(ABC) transporter
EQG49_RS03385	COG0537	adenosine 5'-monophosphoramidase activity
EQG49_RS03400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQG49_RS03415	COG1484	DNA-dependent DNA replication
EQG49_RS03420	COG3611	Membrane attachment protein
EQG49_RS03425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQG49_RS03435	COG3613	nucleoside 2-deoxyribosyltransferase
EQG49_RS03440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQG49_RS03475	COG2246	polysaccharide biosynthetic process
EQG49_RS03495	COG4555	ABC transporter
EQG49_RS03515	COG0673	inositol 2-dehydrogenase activity
EQG49_RS03520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQG49_RS03525	COG1426	Protein conserved in bacteria
EQG49_RS03530	COG0612	Peptidase, M16
EQG49_RS03535	COG0612	Peptidase, M16
EQG49_RS03545	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQG49_RS03555	COG0562	UDP-galactopyranose mutase
EQG49_RS03570	COG1063	alcohol dehydrogenase
EQG49_RS03575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQG49_RS03595	COG0463	Glycosyl transferase, family 2
EQG49_RS03605	COG0463	Glycosyl transferase, family 2
EQG49_RS03610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQG49_RS03690	COG0802	atpase or kinase
EQG49_RS03700	COG2176	DNA-directed DNA polymerase activity
EQG49_RS03710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQG49_RS03735	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQG49_RS03765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQG49_RS03770	COG0494	nUDIX hydrolase
EQG49_RS03780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQG49_RS03790	COG0589	response to stress
EQG49_RS03800	COG0004	ammonium transporteR
EQG49_RS03805	COG1482	cell wall glycoprotein biosynthetic process
EQG49_RS03810	COG0346	lactoylglutathione lyase activity
EQG49_RS03820	COG0791	NLP P60 protein
EQG49_RS03820	COG1388	LysM domain
EQG49_RS03835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQG49_RS03845	COG0363	glucosamine-6-phosphate deaminase activity
EQG49_RS03850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQG49_RS03855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQG49_RS03870	COG0740	serine-type endopeptidase activity
EQG49_RS03875	COG1481	regulation of sporulation
EQG49_RS03880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQG49_RS03920	COG1132	(ABC) transporter
EQG49_RS03950	COG1464	Belongs to the NlpA lipoprotein family
EQG49_RS03985	COG1063	alcohol dehydrogenase
EQG49_RS03990	COG1940	carbohydrate kinase activity
EQG49_RS04005	COG1132	(ABC) transporter
EQG49_RS04065	COG1131	(ABC) transporter
EQG49_RS04075	COG0477	Major facilitator Superfamily
EQG49_RS04120	COG2244	polysaccharide biosynthetic process
EQG49_RS04245	COG3157	Type VI secretion system effector, Hcp
EQG49_RS04295	COG2801	Transposase and inactivated derivatives
EQG49_RS04430	COG1396	sequence-specific DNA binding
EQG49_RS04480	COG0626	cystathionine gamma-synthase activity
EQG49_RS04490	COG1902	pentaerythritol trinitrate reductase activity
EQG49_RS04500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EQG49_RS04515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EQG49_RS04530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EQG49_RS04540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EQG49_RS04555	COG0737	Belongs to the 5'-nucleotidase family
EQG49_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS04595	COG0527	aspartate kinase activity
EQG49_RS04600	COG1473	amidohydrolase
EQG49_RS04610	COG0435	Glutathione S-transferase
EQG49_RS04615	COG0435	Glutathione S-transferase
EQG49_RS04620	COG1126	abc transporter atp-binding protein
EQG49_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS04635	COG0626	cystathionine gamma-synthase activity
EQG49_RS04640	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EQG49_RS04645	COG0460	homoserine dehydrogenase
EQG49_RS04660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EQG49_RS04665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQG49_RS04675	COG0590	tRNA wobble adenosine to inosine editing
EQG49_RS04680	COG2813	Specifically methylates the guanine in position
EQG49_RS04685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQG49_RS04690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQG49_RS04695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQG49_RS04700	COG1611	Belongs to the LOG family
EQG49_RS04730	COG0222	ribosome binding
EQG49_RS04735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQG49_RS04740	COG0081	regulation of translation
EQG49_RS04745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQG49_RS04750	COG0534	Mate efflux family protein
EQG49_RS04765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQG49_RS04775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQG49_RS04780	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQG49_RS04785	COG0215	cysteine-tRNA ligase activity
EQG49_RS04800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQG49_RS04805	COG4956	integral membrane protein (PIN domain superfamily)
EQG49_RS04815	COG0756	dUTP diphosphatase activity
EQG49_RS04825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EQG49_RS04855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQG49_RS04860	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS04860	COG3951	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS04865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQG49_RS04870	COG4988	ABC transporter
EQG49_RS04875	COG1294	oxidase, subunit
EQG49_RS04880	COG1271	oxidase subunit
EQG49_RS04885	COG1464	Belongs to the NlpA lipoprotein family
EQG49_RS04895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQG49_RS04905	COG2188	Transcriptional regulator
EQG49_RS04910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQG49_RS04915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQG49_RS04940	COG3104	oligopeptide transport
EQG49_RS04950	COG0531	amino acid
EQG49_RS04970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQG49_RS05025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQG49_RS05030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQG49_RS05035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQG49_RS05050	COG0037	tRNA processing
EQG49_RS05060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQG49_RS05065	COG2244	polysaccharide biosynthetic process
EQG49_RS05070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQG49_RS05095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQG49_RS05100	COG0556	nucleotide-excision repair
EQG49_RS05135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQG49_RS05140	COG0492	ferredoxin-NADP+ reductase activity
EQG49_RS05170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQG49_RS05175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQG49_RS05180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EQG49_RS05185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQG49_RS05190	COG1950	PFAM Membrane protein of
EQG49_RS05195	COG1983	PspC domain protein
EQG49_RS05205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQG49_RS05210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQG49_RS05215	COG0581	inorganic phosphate transmembrane transporter activity
EQG49_RS05220	COG0573	inorganic phosphate transmembrane transporter activity
EQG49_RS05250	COG5002	protein histidine kinase activity
EQG49_RS05255	COG0745	RESPONSE REGULATOR receiver
EQG49_RS05260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EQG49_RS05265	COG0653	protein targeting
EQG49_RS05280	COG1040	competence protein
EQG49_RS05285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQG49_RS05290	COG1739	Uncharacterized protein family UPF0029
EQG49_RS05300	COG1376	ErfK ybiS ycfS ynhG family protein
EQG49_RS05305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQG49_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
EQG49_RS05360	COG1846	Transcriptional regulator
EQG49_RS05370	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQG49_RS05390	COG0531	amino acid
EQG49_RS05420	COG1575	Belongs to the MenA family. Type 1 subfamily
EQG49_RS05435	COG2233	PERMEase
EQG49_RS05440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQG49_RS05470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQG49_RS05480	COG2096	Adenosyltransferase
EQG49_RS05525	COG0477	Major facilitator Superfamily
EQG49_RS05530	COG1082	Xylose isomerase domain protein TIM barrel
EQG49_RS05535	COG4975	Glucose uptake
EQG49_RS05540	COG0673	inositol 2-dehydrogenase activity
EQG49_RS05555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQG49_RS05570	COG1131	(ABC) transporter
EQG49_RS05605	COG1122	ATPase activity
EQG49_RS05610	COG1122	ATPase activity
EQG49_RS05620	COG1252	NADH dehydrogenase
EQG49_RS05640	COG0588	phosphoglycerate mutase activity
EQG49_RS05680	COG0726	polysaccharide deacetylase
EQG49_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
EQG49_RS05745	COG0163	prenyltransferase activity
EQG49_RS05750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EQG49_RS05760	COG0583	DNA-binding transcription factor activity
EQG49_RS05780	COG0203	ribosomal protein L17
EQG49_RS05785	COG0202	RNA polymerase activity
EQG49_RS05790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQG49_RS05795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQG49_RS05800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQG49_RS05805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQG49_RS05820	COG0200	Binds to the 23S rRNA
EQG49_RS05825	COG1841	ribosomal large subunit assembly
EQG49_RS05830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQG49_RS05835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQG49_RS05840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQG49_RS05845	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQG49_RS05855	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQG49_RS05860	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQG49_RS05865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQG49_RS05870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQG49_RS05875	COG0255	Belongs to the universal ribosomal protein uL29 family
EQG49_RS05885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQG49_RS05890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQG49_RS05895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQG49_RS05900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQG49_RS05905	COG0089	rRNA binding
EQG49_RS05915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQG49_RS05920	COG0051	transcription antitermination factor activity, RNA binding
EQG49_RS05925	COG1335	isochorismatase
EQG49_RS05935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQG49_RS05950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EQG49_RS05955	COG3842	ATPase activity
EQG49_RS05960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQG49_RS05965	COG0049	tRNA binding
EQG49_RS05970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQG49_RS05980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQG49_RS05985	COG0085	RNA polymerase activity
EQG49_RS05990	COG0542	response to heat
EQG49_RS05995	COG4463	regulation of RNA biosynthetic process
EQG49_RS06040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQG49_RS06045	COG1428	Deoxynucleoside kinase
EQG49_RS06050	COG0833	amino acid
EQG49_RS06065	COG1959	2 iron, 2 sulfur cluster binding
EQG49_RS06075	COG0730	response to heat
EQG49_RS06085	COG1316	TRANSCRIPTIONal
EQG49_RS06095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQG49_RS06100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQG49_RS06115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQG49_RS06120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQG49_RS06125	COG0561	phosphatase activity
EQG49_RS06130	COG3764	Sortase (surface protein transpeptidase)
EQG49_RS06140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQG49_RS06140	COG1263	PTS System
EQG49_RS06140	COG2190	(PTS) system
EQG49_RS06165	COG0400	carboxylic ester hydrolase activity
EQG49_RS06170	COG0346	lactoylglutathione lyase activity
EQG49_RS06175	COG1307	EDD domain protein, DegV family
EQG49_RS06180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQG49_RS06185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQG49_RS06195	COG4120	Belongs to the binding-protein-dependent transport system permease family
EQG49_RS06215	COG1780	Probably involved in ribonucleotide reductase function
EQG49_RS06220	COG0561	phosphatase activity
EQG49_RS06230	COG1116	anion transmembrane transporter activity
EQG49_RS06250	COG1396	sequence-specific DNA binding
EQG49_RS06255	COG2814	Major facilitator Superfamily
EQG49_RS06345	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS06350	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS06360	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS06365	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS06380	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS06420	COG0840	transmembrane signaling receptor activity
EQG49_RS06420	COG5278	phosphoserine phosphatase activity
EQG49_RS06440	COG0248	Ppx GppA phosphatase
EQG49_RS06465	COG1744	ABC transporter substrate-binding protein PnrA-like
EQG49_RS06470	COG0737	Belongs to the 5'-nucleotidase family
EQG49_RS06475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQG49_RS06480	COG1373	ATPase (AAA superfamily
EQG49_RS06485	COG0180	Tryptophanyl-tRNA synthetase
EQG49_RS06490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQG49_RS06495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQG49_RS06500	COG2252	PERMEase
EQG49_RS06550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQG49_RS06575	COG0463	Glycosyl transferase, family 2
EQG49_RS06605	COG0583	DNA-binding transcription factor activity
EQG49_RS06610	COG0346	lactoylglutathione lyase activity
EQG49_RS06645	COG1136	(ABC) transporter
EQG49_RS06645	COG0577	efflux transmembrane transporter activity
EQG49_RS06650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS06655	COG0765	amino acid transport
EQG49_RS06660	COG2855	membrane
EQG49_RS06670	COG0656	L-ascorbic acid biosynthetic process
EQG49_RS06680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQG49_RS06685	COG0028	Belongs to the TPP enzyme family
EQG49_RS06690	COG3527	Alpha-acetolactate decarboxylase
EQG49_RS06720	COG4152	abc transporter atp-binding protein
EQG49_RS06725	COG1668	transmembrane transport
EQG49_RS06735	COG1316	TRANSCRIPTIONal
EQG49_RS06755	COG1045	serine acetyltransferase
EQG49_RS06790	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQG49_RS06800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQG49_RS06805	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQG49_RS06820	COG4863	YycH protein
EQG49_RS06825	COG5002	protein histidine kinase activity
EQG49_RS06830	COG0745	RESPONSE REGULATOR receiver
EQG49_RS06905	COG1393	Belongs to the ArsC family
EQG49_RS06920	COG0488	(ABC) transporter
EQG49_RS06930	COG0488	(ABC) transporter
EQG49_RS06950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQG49_RS06955	COG0436	Aminotransferase
EQG49_RS06980	COG0477	Major facilitator Superfamily
EQG49_RS07015	COG0300	oxidoreductase activity
EQG49_RS07020	COG0604	alcohol dehydrogenase
EQG49_RS07020	COG3321	synthase
EQG49_RS07025	COG1309	transcriptional regulator
EQG49_RS07030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQG49_RS07030	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQG49_RS07055	COG2814	Major facilitator Superfamily
EQG49_RS07090	COG2409	Drug exporters of the RND superfamily
EQG49_RS07105	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQG49_RS07110	COG0305	Participates in initiation and elongation during chromosome replication
EQG49_RS07115	COG0359	binds to the 23S rRNA
EQG49_RS07125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQG49_RS07130	COG0629	single-stranded DNA binding
EQG49_RS07135	COG0360	Binds together with S18 to 16S ribosomal RNA
EQG49_RS07145	COG0419	ATPase involved in DNA repair
EQG49_RS07150	COG0420	3'-5' exonuclease activity
EQG49_RS07155	COG1132	(ABC) transporter
EQG49_RS07185	COG0187	DNA topoisomerase II activity
EQG49_RS07190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQG49_RS07200	COG0592	DNA-directed DNA polymerase activity
EQG49_RS07205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQG49_RS07210	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EQG49_RS07215	COG0594	ribonuclease P activity
EQG49_RS07220	COG0706	membrane insertase activity
EQG49_RS07230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQG49_RS07265	COG2814	Major facilitator Superfamily
EQG49_RS07270	COG1847	R3H domain protein
EQG49_RS07295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQG49_RS07300	COG0445	tRNA wobble uridine modification
EQG49_RS07310	COG1252	NADH dehydrogenase
EQG49_RS07320	COG3279	Response regulator of the LytR AlgR family
EQG49_RS07365	COG2409	Drug exporters of the RND superfamily
EQG49_RS07365	COG1033	growth of symbiont in host cell
EQG49_RS07370	COG0681	Belongs to the peptidase S26 family
EQG49_RS07380	COG0569	domain protein
EQG49_RS07385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQG49_RS07390	COG2918	glutathione biosynthetic process
EQG49_RS07390	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQG49_RS07405	COG1388	LysM domain
EQG49_RS07405	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS07410	COG1228	amidohydrolase
EQG49_RS07420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EQG49_RS07430	COG0604	alcohol dehydrogenase
EQG49_RS07480	COG1174	glycine betaine transport
EQG49_RS07485	COG1125	glycine betaine transport
EQG49_RS07490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQG49_RS07500	COG3973	AAA domain
EQG49_RS07515	COG2814	Major facilitator Superfamily
EQG49_RS07530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQG49_RS07530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQG49_RS07540	COG0084	hydrolase, TatD family'
EQG49_RS07545	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQG49_RS07550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQG49_RS07555	COG4466	Protein conserved in bacteria
EQG49_RS07560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQG49_RS07565	COG3275	phosphorelay sensor kinase activity
EQG49_RS07570	COG3279	Response regulator of the LytR AlgR family
EQG49_RS07595	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQG49_RS07600	COG1121	(ABC) transporter
EQG49_RS07605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQG49_RS07610	COG0351	phosphomethylpyrimidine kinase
EQG49_RS07620	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS07640	COG2017	converts alpha-aldose to the beta-anomer
EQG49_RS07645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQG49_RS07665	COG0076	glutamate decarboxylase activity
EQG49_RS07680	COG0492	ferredoxin-NADP+ reductase activity
EQG49_RS07690	COG0038	chloride channel
EQG49_RS07705	COG0673	inositol 2-dehydrogenase activity
EQG49_RS07715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EQG49_RS07720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EQG49_RS07725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EQG49_RS07730	COG0297	glycogen (starch) synthase activity
EQG49_RS07735	COG0058	SHG alpha-glucan phosphorylase activity
EQG49_RS07740	COG0366	Alpha amylase catalytic
EQG49_RS07740	COG3103	Sh3 type 3 domain protein
EQG49_RS07770	COG1114	Component of the transport system for branched-chain amino acids
EQG49_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS07815	COG2814	Major facilitator Superfamily
EQG49_RS07860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQG49_RS07865	COG1131	(ABC) transporter
EQG49_RS07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS07875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQG49_RS07880	COG1418	mRNA catabolic process
EQG49_RS07890	COG2188	Transcriptional regulator
EQG49_RS07895	COG3548	integral membrane protein
EQG49_RS07900	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EQG49_RS07910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQG49_RS07915	COG0588	phosphoglycerate mutase activity
EQG49_RS07920	COG3973	AAA domain
EQG49_RS07935	COG2814	Major facilitator Superfamily
EQG49_RS07945	COG1230	cation diffusion facilitator family transporter
EQG49_RS07950	COG1278	Cold shock
EQG49_RS07955	COG0357	Ribosomal RNA small subunit methyltransferase G
EQG49_RS07965	COG1192	Involved in chromosome partitioning
EQG49_RS07970	COG1475	DNA binding
EQG49_RS07975	COG4481	Protein conserved in bacteria
EQG49_RS07980	COG0012	GTP binding
EQG49_RS08000	COG1686	Belongs to the peptidase S11 family
EQG49_RS08015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQG49_RS08030	COG1122	ATPase activity
EQG49_RS08035	COG4721	ABC-type cobalt transport system, permease component
EQG49_RS08040	COG0564	pseudouridine synthase activity
EQG49_RS08045	COG3118	belongs to the thioredoxin family
EQG49_RS08050	COG0656	L-ascorbic acid biosynthetic process
EQG49_RS08060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQG49_RS08080	COG0588	phosphoglycerate mutase activity
EQG49_RS08100	COG1064	alcohol dehydrogenase
EQG49_RS08125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQG49_RS08135	COG0628	permease
EQG49_RS08150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQG49_RS08155	COG0436	Aminotransferase
EQG49_RS08175	COG1078	dGTPase activity
EQG49_RS08180	COG0095	Lipoate-protein ligase
EQG49_RS08190	COG3343	RNA polymerase activity
EQG49_RS08200	COG0504	CTP synthase activity
EQG49_RS08205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQG49_RS08210	COG0254	rRNA binding
EQG49_RS08225	COG1737	Transcriptional regulator
EQG49_RS08230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EQG49_RS08240	COG1253	flavin adenine dinucleotide binding
EQG49_RS08250	COG1968	undecaprenyl-diphosphatase activity
EQG49_RS08255	COG3853	Toxic anion resistance protein (TelA)
EQG49_RS08265	COG2084	Dehydrogenase
EQG49_RS08270	COG0789	Transcriptional regulator
EQG49_RS08275	COG0656	L-ascorbic acid biosynthetic process
EQG49_RS08280	COG4989	oxidoreductase activity
EQG49_RS08295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQG49_RS08305	COG1368	sulfuric ester hydrolase activity
EQG49_RS08310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQG49_RS08315	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQG49_RS08320	COG2723	6-phospho-beta-galactosidase activity
EQG49_RS08330	COG2723	6-phospho-beta-galactosidase activity
EQG49_RS08345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQG49_RS08355	COG2183	response to ionizing radiation
EQG49_RS08360	COG3091	SprT-like family
EQG49_RS08370	COG0667	Aldo Keto reductase
EQG49_RS08400	COG0577	efflux transmembrane transporter activity
EQG49_RS08405	COG1136	(ABC) transporter
EQG49_RS08420	COG0745	RESPONSE REGULATOR receiver
EQG49_RS08425	COG5002	protein histidine kinase activity
EQG49_RS08430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQG49_RS08440	COG0736	holo-[acyl-carrier-protein] synthase activity
EQG49_RS08445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQG49_RS08450	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQG49_RS08470	COG2267	carboxylic ester hydrolase activity
EQG49_RS08480	COG1268	BioY protein
EQG49_RS08485	COG2936	dipeptidyl-peptidase activity
EQG49_RS08490	COG0531	amino acid
EQG49_RS08495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQG49_RS08500	COG0194	GDP metabolic process
EQG49_RS08515	COG1126	abc transporter atp-binding protein
EQG49_RS08520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS08525	COG0765	amino acid transport
EQG49_RS08530	COG0765	amino acid transport
EQG49_RS08540	COG4608	Belongs to the ABC transporter superfamily
EQG49_RS08545	COG0601	transmembrane transport
EQG49_RS08550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQG49_RS08560	COG3590	peptidase
EQG49_RS08565	COG3590	peptidase
EQG49_RS08570	COG0531	amino acid
EQG49_RS08595	COG0477	Major facilitator Superfamily
EQG49_RS08600	COG0477	Major facilitator Superfamily
EQG49_RS08610	COG0477	Major facilitator Superfamily
EQG49_RS08620	COG0488	(ABC) transporter
EQG49_RS08655	COG1132	(ABC) transporter
EQG49_RS08660	COG1132	(ABC) transporter
EQG49_RS08670	COG0589	response to stress
EQG49_RS08680	COG1428	Deoxynucleoside kinase
EQG49_RS08690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQG49_RS08700	COG2115	Belongs to the xylose isomerase family
EQG49_RS08705	COG2211	Major facilitator Superfamily
EQG49_RS08710	COG3507	Belongs to the glycosyl hydrolase 43 family
EQG49_RS08715	COG0531	amino acid
EQG49_RS08775	COG4708	membrane
EQG49_RS08780	COG0488	(ABC) transporter
EQG49_RS08785	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQG49_RS08790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQG49_RS08795	COG0459	protein refolding
EQG49_RS08810	COG0823	Involved in the tonB-independent uptake of proteins
EQG49_RS08810	COG4946	Tricorn protease homolog
EQG49_RS08810	COG1506	peptidase
EQG49_RS08815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQG49_RS08820	COG3870	Protein conserved in bacteria
EQG49_RS08825	COG0470	DNA polymerase III
EQG49_RS08830	COG4467	Involved in initiation control of chromosome replication
EQG49_RS08845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQG49_RS08850	COG1214	PFAM Peptidase M22, glycoprotease
EQG49_RS08860	COG0456	acetyltransferase
EQG49_RS08865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQG49_RS08880	COG0477	Major facilitator Superfamily
EQG49_RS08895	COG1278	Cold shock
EQG49_RS08905	COG0561	phosphatase activity
EQG49_RS08935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQG49_RS08940	COG1131	(ABC) transporter
EQG49_RS08950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQG49_RS08965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQG49_RS09030	COG1215	transferase activity, transferring glycosyl groups
EQG49_RS09030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQG49_RS09040	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS09040	COG1388	LysM domain
EQG49_RS09090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQG49_RS09095	COG3475	LICD family
EQG49_RS09110	COG2137	regulation of response to DNA damage stimulus
EQG49_RS09115	COG3557	Belongs to the UPF0374 family
EQG49_RS09120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQG49_RS09140	COG1846	Transcriptional regulator
EQG49_RS09180	COG0126	phosphoglycerate kinase activity
EQG49_RS09190	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EQG49_RS09200	COG3639	organic phosphonate transmembrane transporter activity
EQG49_RS09205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQG49_RS09210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EQG49_RS09215	COG0149	triose-phosphate isomerase activity
EQG49_RS09240	COG1164	Oligoendopeptidase f
EQG49_RS09255	COG1686	Belongs to the peptidase S11 family
EQG49_RS09265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EQG49_RS09270	COG2801	Transposase and inactivated derivatives
EQG49_RS09295	COG0542	response to heat
EQG49_RS09310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQG49_RS09320	COG0438	transferase activity, transferring glycosyl groups
EQG49_RS09335	COG1368	sulfuric ester hydrolase activity
EQG49_RS09415	COG0561	phosphatase activity
EQG49_RS09430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQG49_RS09440	COG3715	PTS system
EQG49_RS09445	COG3716	PTS system mannose fructose sorbose family IID component
EQG49_RS09460	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQG49_RS09465	COG0671	phosphoesterase, PA-phosphatase related
EQG49_RS09470	COG0495	leucyl-tRNA aminoacylation
EQG49_RS09480	COG2814	Major facilitator Superfamily
EQG49_RS09485	COG0735	belongs to the Fur family
EQG49_RS09500	COG1914	H( )-stimulated, divalent metal cation uptake system
EQG49_RS09515	COG0640	Transcriptional regulator
EQG49_RS09525	COG1914	H( )-stimulated, divalent metal cation uptake system
EQG49_RS09550	COG1132	(ABC) transporter
EQG49_RS09555	COG0577	efflux transmembrane transporter activity
EQG49_RS09555	COG1136	(ABC) transporter
EQG49_RS09560	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQG49_RS09570	COG0628	permease
EQG49_RS09580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQG49_RS09585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQG49_RS09590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQG49_RS09595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQG49_RS09600	COG1126	abc transporter atp-binding protein
EQG49_RS09605	COG0765	amino acid transport
EQG49_RS09630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQG49_RS09635	COG0280	phosphate acetyltransferase
EQG49_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
EQG49_RS09640	COG1454	alcohol dehydrogenase
EQG49_RS09645	COG1956	GAF domain-containing protein
EQG49_RS09650	COG0285	dihydrofolate synthase activity
EQG49_RS09655	COG2003	Belongs to the UPF0758 family
EQG49_RS09660	COG1704	LemA family
EQG49_RS09665	COG0501	Belongs to the peptidase M48B family
EQG49_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
EQG49_RS09690	COG4975	Glucose uptake
EQG49_RS09695	COG1309	transcriptional regulator
EQG49_RS09700	COG0300	oxidoreductase activity
EQG49_RS09705	COG3442	glutamine amidotransferase
EQG49_RS09710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQG49_RS09715	COG1435	thymidine kinase activity
EQG49_RS09720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQG49_RS09725	COG2890	protein-(glutamine-N5) methyltransferase activity
EQG49_RS09730	COG0009	L-threonylcarbamoyladenylate synthase
EQG49_RS09740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQG49_RS09745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQG49_RS09755	COG2233	PERMEase
EQG49_RS09765	COG0356	it plays a direct role in the translocation of protons across the membrane
EQG49_RS09770	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQG49_RS09775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQG49_RS09780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQG49_RS09785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQG49_RS09790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQG49_RS09795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQG49_RS09800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQG49_RS09810	COG1077	Cell shape determining protein MreB Mrl
EQG49_RS09815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQG49_RS09825	COG0772	Belongs to the SEDS family
EQG49_RS09845	COG0745	RESPONSE REGULATOR receiver
EQG49_RS09850	COG5002	protein histidine kinase activity
EQG49_RS09850	COG3850	Histidine kinase
EQG49_RS09855	COG2017	converts alpha-aldose to the beta-anomer
EQG49_RS09860	COG4975	Glucose uptake
EQG49_RS09870	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS09870	COG1388	LysM domain
EQG49_RS09875	COG2309	aminopeptidase activity
EQG49_RS09880	COG0024	Methionine aminopeptidase
EQG49_RS09885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQG49_RS09890	COG1134	teichoic acid transport
EQG49_RS09895	COG1682	transport, permease protein
EQG49_RS09900	COG1546	Belongs to the CinA family
EQG49_RS09900	COG1058	Belongs to the CinA family
EQG49_RS09905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQG49_RS09910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQG49_RS09915	COG1570	exodeoxyribonuclease VII activity
EQG49_RS09920	COG1722	exodeoxyribonuclease VII activity
EQG49_RS09930	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EQG49_RS09935	COG1438	arginine binding
EQG49_RS09940	COG0497	DNA recombination
EQG49_RS09950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQG49_RS09955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQG49_RS09960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQG49_RS09975	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQG49_RS09980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQG49_RS09985	COG1534	Rna-binding protein
EQG49_RS09990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQG49_RS09995	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQG49_RS10000	COG0799	negative regulation of ribosome biogenesis
EQG49_RS10005	COG2226	methyltransferase
EQG49_RS10040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQG49_RS10045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQG49_RS10050	COG0632	four-way junction helicase activity
EQG49_RS10055	COG2255	four-way junction helicase activity
EQG49_RS10060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQG49_RS10065	COG0343	queuine tRNA-ribosyltransferase activity
EQG49_RS10070	COG1862	Preprotein translocase
EQG49_RS10075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQG49_RS10080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQG49_RS10085	COG0513	Belongs to the DEAD box helicase family
EQG49_RS10090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQG49_RS10095	COG1302	Protein conserved in bacteria
EQG49_RS10100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQG49_RS10115	COG0095	Lipoate-protein ligase
EQG49_RS10130	COG1979	alcohol dehydrogenase
EQG49_RS10140	COG0540	Belongs to the ATCase OTCase family
EQG49_RS10150	COG0505	Belongs to the CarA family
EQG49_RS10155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQG49_RS10160	COG0167	dihydroorotate dehydrogenase activity
EQG49_RS10165	COG0284	orotidine-5'-phosphate decarboxylase activity
EQG49_RS10180	COG0167	dihydroorotate dehydrogenase activity
EQG49_RS10185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQG49_RS10215	COG0745	RESPONSE REGULATOR receiver
EQG49_RS10225	COG1254	Belongs to the acylphosphatase family
EQG49_RS10235	COG0586	Pfam SNARE associated Golgi protein
EQG49_RS10245	COG1185	polyribonucleotide nucleotidyltransferase activity
EQG49_RS10370	COG0017	Asparaginyl-tRNA synthetase
EQG49_RS10385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQG49_RS10390	COG4493	Belongs to the UPF0637 family
EQG49_RS10400	COG0489	protein tyrosine kinase activity
EQG49_RS10440	COG1012	belongs to the aldehyde dehydrogenase family
EQG49_RS10445	COG0514	ATP-dependent DNA helicase (RecQ)
EQG49_RS10450	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EQG49_RS10460	COG1511	domain protein
EQG49_RS10495	COG2814	Major facilitator Superfamily
EQG49_RS10500	COG1733	regulation of RNA biosynthetic process
EQG49_RS10520	COG0454	-acetyltransferase
EQG49_RS10545	COG2814	Major facilitator Superfamily
EQG49_RS10565	COG0477	Major facilitator Superfamily
EQG49_RS10580	COG5658	integral membrane protein
EQG49_RS10590	COG1309	transcriptional regulator
EQG49_RS10595	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQG49_RS10610	COG2801	Transposase and inactivated derivatives
EQG49_RS10615	COG1420	regulation of RNA biosynthetic process
EQG49_RS10620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQG49_RS10625	COG0443	Heat shock 70 kDa protein
EQG49_RS10630	COG0484	heat shock protein binding
EQG49_RS10635	COG1113	amino acid transport
EQG49_RS10645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQG49_RS10650	COG0705	Rhomboid family
EQG49_RS10650	COG0457	Tetratricopeptide repeat
EQG49_RS10670	COG3715	PTS system
EQG49_RS10675	COG3716	PTS system mannose fructose sorbose family IID component
EQG49_RS10685	COG3069	C4-dicarboxylate transmembrane transporter activity
EQG49_RS10705	COG0006	proline dipeptidase activity
EQG49_RS10710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQG49_RS10715	COG1490	D-aminoacyl-tRNA deacylase activity
EQG49_RS10725	COG0673	inositol 2-dehydrogenase activity
EQG49_RS10730	COG0322	excinuclease ABC activity
EQG49_RS10735	COG0772	Belongs to the SEDS family
EQG49_RS10740	COG4471	UPF0298 protein
EQG49_RS10745	COG0742	ribosomal rna small subunit methyltransferase
EQG49_RS10750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQG49_RS10755	COG3480	Lon protease (S16) C-terminal proteolytic domain
EQG49_RS10760	COG0849	cell division
EQG49_RS10770	COG1799	cell septum assembly
EQG49_RS10775	COG0762	integral membrane protein
EQG49_RS10785	COG3599	regulation of cell shape
EQG49_RS10795	COG4975	Glucose uptake
EQG49_RS10830	COG1114	Component of the transport system for branched-chain amino acids
EQG49_RS10840	COG0584	glycerophosphoryl diester phosphodiesterase
EQG49_RS10845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQG49_RS10850	COG0789	Transcriptional regulator
EQG49_RS10855	COG0174	glutamine synthetase
EQG49_RS10880	COG1309	transcriptional regulator
EQG49_RS10925	COG3830	Belongs to the UPF0237 family
EQG49_RS10930	COG2848	UPF0210 protein
EQG49_RS10935	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EQG49_RS10940	COG1518	maintenance of DNA repeat elements
EQG49_RS10960	COG1438	arginine binding
EQG49_RS10965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQG49_RS10970	COG3679	Belongs to the UPF0342 family
EQG49_RS10975	COG0706	membrane insertase activity
EQG49_RS10980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQG49_RS10985	COG1070	Carbohydrate kinase
EQG49_RS10995	COG1733	regulation of RNA biosynthetic process
EQG49_RS11010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQG49_RS11015	COG0072	phenylalanine-tRNA ligase activity
EQG49_RS11015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQG49_RS11020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQG49_RS11105	COG0629	single-stranded DNA binding
EQG49_RS11140	COG5484	DNA packaging
EQG49_RS11300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQG49_RS11305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQG49_RS11315	COG1126	abc transporter atp-binding protein
EQG49_RS11320	COG3118	belongs to the thioredoxin family
EQG49_RS11330	COG0477	Major facilitator Superfamily
EQG49_RS11340	COG2723	6-phospho-beta-galactosidase activity
EQG49_RS11345	COG1596	polysaccharide export
EQG49_RS11345	COG1555	photosystem II stabilization
EQG49_RS11350	COG2131	deaminase
EQG49_RS11355	COG0658	competence protein
EQG49_RS11355	COG2333	competence protein COMEC
EQG49_RS11360	COG1466	dna polymerase III delta subunit
EQG49_RS11365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQG49_RS11370	COG0268	Binds directly to 16S ribosomal RNA
EQG49_RS11375	COG2384	SAM-dependent methyltransferase
EQG49_RS11380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQG49_RS11395	COG0587	DNA-directed DNA polymerase activity
EQG49_RS11415	COG1914	H( )-stimulated, divalent metal cation uptake system
EQG49_RS11425	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQG49_RS11440	COG1193	negative regulation of DNA recombination
EQG49_RS11455	COG1610	YqeY-like protein
EQG49_RS11460	COG1162	GTPase activity
EQG49_RS11465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQG49_RS11475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQG49_RS11485	COG1461	Dihydroxyacetone kinase
EQG49_RS11490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQG49_RS11495	COG0416	fatty acid biosynthetic process
EQG49_RS11500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQG49_RS11505	COG0571	ribonuclease III activity
EQG49_RS11510	COG1196	nuclear chromosome segregation
EQG49_RS11515	COG0552	protein localization to endoplasmic reticulum
EQG49_RS11520	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQG49_RS11525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQG49_RS11535	COG0228	four-way junction DNA binding
EQG49_RS11555	COG1869	D-ribose catabolic process
EQG49_RS11565	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQG49_RS11570	COG1879	ABC-type sugar transport system periplasmic component
EQG49_RS11585	COG0336	Belongs to the RNA methyltransferase TrmD family
EQG49_RS11590	COG0527	aspartate kinase activity
EQG49_RS11595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQG49_RS11605	COG2171	N-acyltransferase activity
EQG49_RS11610	COG1473	amidohydrolase
EQG49_RS11615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQG49_RS11620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQG49_RS11625	COG0436	Aminotransferase
EQG49_RS11630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQG49_RS11675	COG2076	Multidrug Resistance protein
EQG49_RS11680	COG2076	Multidrug Resistance protein
EQG49_RS11725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQG49_RS11730	COG0438	transferase activity, transferring glycosyl groups
EQG49_RS11735	COG0438	transferase activity, transferring glycosyl groups
EQG49_RS11740	COG1215	transferase activity, transferring glycosyl groups
EQG49_RS11750	COG1215	transferase activity, transferring glycosyl groups
EQG49_RS11765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQG49_RS11770	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQG49_RS11820	COG3048	D-serine ammonia-lyase activity
EQG49_RS11835	COG3201	nicotinamide mononucleotide transporter
EQG49_RS11840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQG49_RS11855	COG1388	LysM domain
EQG49_RS11855	COG0791	NLP P60 protein
EQG49_RS11880	COG1725	Transcriptional regulator
EQG49_RS11885	COG1131	(ABC) transporter
EQG49_RS11935	COG2270	Major facilitator Superfamily
EQG49_RS11940	COG0124	histidyl-tRNA synthetase
EQG49_RS11945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQG49_RS11970	COG0604	alcohol dehydrogenase
EQG49_RS11985	COG1137	ATPase activity
EQG49_RS12010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQG49_RS12015	COG4974	Belongs to the 'phage' integrase family
EQG49_RS12030	COG0242	peptide deformylase activity
EQG49_RS12060	COG1113	amino acid transport
EQG49_RS12065	COG0779	Required for maturation of 30S ribosomal subunits
EQG49_RS12070	COG0195	Participates in both transcription termination and antitermination
EQG49_RS12075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQG49_RS12085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQG49_RS12090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQG49_RS12095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQG49_RS12100	COG0196	riboflavin kinase activity
EQG49_RS12120	COG0308	aminopeptidase N
EQG49_RS12125	COG0752	glycyl-tRNA synthetase alpha subunit
EQG49_RS12135	COG0583	DNA-binding transcription factor activity
EQG49_RS12150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQG49_RS12155	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EQG49_RS12160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQG49_RS12165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQG49_RS12200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQG49_RS12205	COG0617	tRNA 3'-terminal CCA addition
EQG49_RS12210	COG0488	(ABC) transporter
EQG49_RS12215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQG49_RS12250	COG0006	proline dipeptidase activity
EQG49_RS12255	COG1609	Transcriptional regulator
EQG49_RS12260	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQG49_RS12265	COG0217	transcriptional regulatory protein
EQG49_RS12280	COG0483	inositol monophosphate 1-phosphatase activity
EQG49_RS12345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQG49_RS12350	COG0328	RNA-DNA hybrid ribonuclease activity
EQG49_RS12360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQG49_RS12365	COG0564	pseudouridine synthase activity
EQG49_RS12370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQG49_RS12375	COG0505	Belongs to the CarA family
EQG49_RS12380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQG49_RS12405	COG2746	aminoglycoside 3-N-acetyltransferase activity
EQG49_RS12410	COG1122	ATPase activity
EQG49_RS12460	COG4977	sequence-specific DNA binding
EQG49_RS12460	COG1917	Cupin 2, conserved barrel domain protein
EQG49_RS12490	COG2246	polysaccharide biosynthetic process
EQG49_RS12495	COG1854	S-ribosylhomocysteine lyase activity
EQG49_RS12500	COG1719	4-vinyl reductase, 4VR
EQG49_RS12505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQG49_RS12510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQG49_RS12515	COG0622	Phosphoesterase
EQG49_RS12530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQG49_RS12535	COG0028	Belongs to the TPP enzyme family
EQG49_RS12540	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQG49_RS12545	COG1074	ATP-dependent DNA helicase activity
EQG49_RS12550	COG0039	L-malate dehydrogenase activity
EQG49_RS12555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQG49_RS12560	COG4841	protein insertion into membrane
EQG49_RS12570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQG49_RS12580	COG0667	Aldo Keto reductase
EQG49_RS12590	COG1983	PspC domain protein
EQG49_RS12770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQG49_RS12840	COG0791	NLP P60 protein
EQG49_RS12930	COG2264	protein methyltransferase activity
EQG49_RS12935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQG49_RS12945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQG49_RS12950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQG49_RS12955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQG49_RS12955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQG49_RS12965	COG0514	ATP-dependent DNA helicase (RecQ)
EQG49_RS12975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQG49_RS12980	COG0539	negative regulation of cytoplasmic translation
EQG49_RS12985	COG1160	GTP binding
EQG49_RS12990	COG0457	Tetratricopeptide repeat
EQG49_RS13010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EQG49_RS13015	COG0248	Ppx GppA phosphatase
EQG49_RS13025	COG1702	phosphate starvation-inducible protein PhoH
EQG49_RS13030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQG49_RS13040	COG0137	argininosuccinate synthase activity
EQG49_RS13045	COG0165	Argininosuccinate lyase
EQG49_RS13050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQG49_RS13090	COG1309	transcriptional regulator
EQG49_RS13095	COG0513	Belongs to the DEAD box helicase family
EQG49_RS13100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQG49_RS13105	COG1942	4-Oxalocrotonate Tautomerase
EQG49_RS13110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQG49_RS13115	COG1309	transcriptional regulator
EQG49_RS13130	COG1397	ADP-ribosylglycohydrolase
EQG49_RS13135	COG1597	lipid kinase activity
EQG49_RS13155	COG1307	EDD domain protein, DegV family
EQG49_RS13160	COG2755	lipolytic protein G-D-S-L family
EQG49_RS13170	COG4479	Belongs to the UPF0346 family
EQG49_RS13185	COG0758	DNA mediated transformation
EQG49_RS13190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQG49_RS13200	COG0025	NhaP-type Na H and K H
EQG49_RS13205	COG4464	protein tyrosine phosphatase activity
EQG49_RS13210	COG1381	Involved in DNA repair and RecF pathway recombination
EQG49_RS13215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EQG49_RS13245	COG4974	Belongs to the 'phage' integrase family
EQG49_RS13375	COG0542	response to heat
EQG49_RS13415	COG3177	Filamentation induced by cAMP protein fic
EQG49_RS13485	COG0791	NLP P60 protein
EQG49_RS13515	COG4974	Belongs to the 'phage' integrase family
EQG49_RS13520	COG0352	thiamine-phosphate diphosphorylase activity
EQG49_RS13525	COG0351	phosphomethylpyrimidine kinase
EQG49_RS13530	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQG49_RS13535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway