locus-tag	class	description
GZH44_RS00010	COG0604	alcohol dehydrogenase
GZH44_RS00060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GZH44_RS00060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GZH44_RS00070	COG0670	Belongs to the BI1 family
GZH44_RS00075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GZH44_RS00085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH44_RS00090	COG1363	Peptidase, m42
GZH44_RS00095	COG0572	uridine kinase
GZH44_RS00100	COG5002	protein histidine kinase activity
GZH44_RS00105	COG0745	RESPONSE REGULATOR receiver
GZH44_RS00115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GZH44_RS00120	COG0358	DNA primase activity
GZH44_RS00140	COG1216	Glycosyl transferase, family 2
GZH44_RS00150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GZH44_RS00175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GZH44_RS00180	COG0438	transferase activity, transferring glycosyl groups
GZH44_RS00185	COG2801	Transposase and inactivated derivatives
GZH44_RS00190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GZH44_RS00280	COG0542	response to heat
GZH44_RS00345	COG0446	pyridine nucleotide-disulphide oxidoreductase
GZH44_RS00355	COG1125	glycine betaine transport
GZH44_RS00365	COG2217	Heavy metal translocating P-type atpase
GZH44_RS00395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GZH44_RS00400	COG0738	Major facilitator superfamily
GZH44_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GZH44_RS00430	COG1228	amidohydrolase
GZH44_RS00435	COG4166	transmembrane transport
GZH44_RS00550	COG1131	(ABC) transporter
GZH44_RS00555	COG3655	Transcriptional regulator
GZH44_RS00595	COG1619	proteins homologs of microcin C7 resistance protein MccF
GZH44_RS00635	COG1304	FMN binding
GZH44_RS00640	COG1611	Belongs to the LOG family
GZH44_RS00655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZH44_RS00660	COG1554	hydrolase, family 65, central catalytic
GZH44_RS00665	COG2190	(PTS) system
GZH44_RS00665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZH44_RS00665	COG1263	PTS System
GZH44_RS00675	COG2188	Transcriptional regulator
GZH44_RS00700	COG0024	Methionine aminopeptidase
GZH44_RS00710	COG3706	GGDEF domain
GZH44_RS00730	COG0463	Glycosyl transferase, family 2
GZH44_RS00730	COG1216	Glycosyl transferase, family 2
GZH44_RS00735	COG4166	transmembrane transport
GZH44_RS00750	COG0508	dehydrogenase complex catalyzes the overall conversion of
GZH44_RS00765	COG0095	Lipoate-protein ligase
GZH44_RS00770	COG3480	Lon protease (S16) C-terminal proteolytic domain
GZH44_RS00775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GZH44_RS00780	COG0742	ribosomal rna small subunit methyltransferase
GZH44_RS00785	COG4471	UPF0298 protein
GZH44_RS00790	COG0772	Belongs to the SEDS family
GZH44_RS00795	COG1217	gtp-binding protein TYPA
GZH44_RS00800	COG0483	inositol monophosphate 1-phosphatase activity
GZH44_RS00820	COG5503	Protein of unknown function (DUF1447)
GZH44_RS00830	COG1597	lipid kinase activity
GZH44_RS00840	COG1464	Belongs to the NlpA lipoprotein family
GZH44_RS00845	COG0446	pyridine nucleotide-disulphide oxidoreductase
GZH44_RS00860	COG4175	Glycine betaine
GZH44_RS00860	COG3448	diguanylate cyclase activity
GZH44_RS00870	COG1227	inorganic diphosphatase activity
GZH44_RS00880	COG0187	DNA topoisomerase II activity
GZH44_RS00885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GZH44_RS00895	COG4974	Belongs to the 'phage' integrase family
GZH44_RS00900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GZH44_RS00905	COG0758	DNA mediated transformation
GZH44_RS00910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GZH44_RS00920	COG4479	Belongs to the UPF0346 family
GZH44_RS00930	COG2755	lipolytic protein G-D-S-L family
GZH44_RS00935	COG1307	EDD domain protein, DegV family
GZH44_RS00940	COG1307	EDD domain protein, DegV family
GZH44_RS00950	COG3142	Participates in the control of copper homeostasis
GZH44_RS00960	COG0196	riboflavin kinase activity
GZH44_RS00965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GZH44_RS00970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GZH44_RS00975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GZH44_RS00985	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GZH44_RS00990	COG0195	Participates in both transcription termination and antitermination
GZH44_RS00995	COG0779	Required for maturation of 30S ribosomal subunits
GZH44_RS01000	COG2239	Acts as a magnesium transporter
GZH44_RS01005	COG0564	pseudouridine synthase activity
GZH44_RS01010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GZH44_RS01015	COG2357	RelA SpoT domain protein
GZH44_RS01030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GZH44_RS01040	COG0546	phosphoglycolate phosphatase activity
GZH44_RS01090	COG3118	belongs to the thioredoxin family
GZH44_RS01095	COG1193	negative regulation of DNA recombination
GZH44_RS01100	COG1286	toxin biosynthetic process
GZH44_RS01110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GZH44_RS01115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GZH44_RS01120	COG0544	peptidyl-prolyl cis-trans isomerase activity
GZH44_RS01125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GZH44_RS01140	COG0268	Binds directly to 16S ribosomal RNA
GZH44_RS01145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GZH44_RS01150	COG1466	dna polymerase III delta subunit
GZH44_RS01155	COG0658	competence protein
GZH44_RS01155	COG2333	competence protein COMEC
GZH44_RS01160	COG1555	photosystem II stabilization
GZH44_RS01160	COG1596	polysaccharide export
GZH44_RS01180	COG4472	Bacterial protein of unknown function (DUF965)
GZH44_RS01185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GZH44_RS01190	COG0513	Belongs to the DEAD box helicase family
GZH44_RS01195	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GZH44_RS01200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GZH44_RS01205	COG1862	Preprotein translocase
GZH44_RS01245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GZH44_RS01250	COG2255	four-way junction helicase activity
GZH44_RS01255	COG0632	four-way junction helicase activity
GZH44_RS01270	COG1739	Uncharacterized protein family UPF0029
GZH44_RS01275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GZH44_RS01280	COG0322	excinuclease ABC activity
GZH44_RS01285	COG1668	transmembrane transport
GZH44_RS01290	COG4152	abc transporter atp-binding protein
GZH44_RS01295	COG1674	ftsk spoiiie
GZH44_RS01305	COG0628	permease
GZH44_RS01310	COG2706	6-phosphogluconolactonase activity
GZH44_RS01315	COG0751	glycine-tRNA ligase activity
GZH44_RS01320	COG0752	glycyl-tRNA synthetase alpha subunit
GZH44_RS01325	COG1381	Involved in DNA repair and RecF pathway recombination
GZH44_RS01330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GZH44_RS01335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GZH44_RS01340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GZH44_RS01345	COG1702	phosphate starvation-inducible protein PhoH
GZH44_RS01350	COG1610	YqeY-like protein
GZH44_RS01355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GZH44_RS01360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GZH44_RS01365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GZH44_RS01370	COG0124	histidyl-tRNA synthetase
GZH44_RS01375	COG0860	N-Acetylmuramoyl-L-alanine amidase
GZH44_RS01385	COG3425	synthase
GZH44_RS01390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GZH44_RS01425	COG0640	Transcriptional regulator
GZH44_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
GZH44_RS01445	COG1063	alcohol dehydrogenase
GZH44_RS01450	COG0789	Transcriptional regulator
GZH44_RS01455	COG0656	L-ascorbic acid biosynthetic process
GZH44_RS01485	COG1309	transcriptional regulator
GZH44_RS01495	COG0531	amino acid
GZH44_RS01500	COG1609	Transcriptional regulator
GZH44_RS01505	COG0006	proline dipeptidase activity
GZH44_RS01520	COG1164	Oligoendopeptidase f
GZH44_RS01530	COG4862	establishment of competence for transformation
GZH44_RS01535	COG1393	Belongs to the ArsC family
GZH44_RS01565	COG0561	phosphatase activity
GZH44_RS01570	COG1970	mechanosensitive ion channel activity
GZH44_RS01575	COG1428	Deoxynucleoside kinase
GZH44_RS01590	COG1942	4-Oxalocrotonate Tautomerase
GZH44_RS01595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GZH44_RS01605	COG0335	large ribosomal subunit rRNA binding
GZH44_RS01610	COG0336	Belongs to the RNA methyltransferase TrmD family
GZH44_RS01615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GZH44_RS01620	COG0588	phosphoglycerate mutase activity
GZH44_RS01625	COG0228	four-way junction DNA binding
GZH44_RS01630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GZH44_RS01635	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GZH44_RS01640	COG0552	protein localization to endoplasmic reticulum
GZH44_RS01645	COG1196	nuclear chromosome segregation
GZH44_RS01650	COG0571	ribonuclease III activity
GZH44_RS01655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GZH44_RS01660	COG0416	fatty acid biosynthetic process
GZH44_RS01665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GZH44_RS01670	COG1461	Dihydroxyacetone kinase
GZH44_RS01680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GZH44_RS01690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GZH44_RS01695	COG1162	GTPase activity
GZH44_RS01700	COG2815	serine threonine protein kinase
GZH44_RS01700	COG0515	serine threonine protein kinase
GZH44_RS01705	COG0631	protein serine/threonine phosphatase activity
GZH44_RS01710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GZH44_RS01710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GZH44_RS01715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GZH44_RS01720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GZH44_RS01725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GZH44_RS01755	COG2165	general secretion pathway protein
GZH44_RS01760	COG1459	type II secretion system
GZH44_RS01765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZH44_RS01770	COG2252	PERMEase
GZH44_RS01775	COG0217	transcriptional regulatory protein
GZH44_RS01780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GZH44_RS01790	COG0588	phosphoglycerate mutase activity
GZH44_RS01800	COG3599	regulation of cell shape
GZH44_RS01815	COG1799	cell septum assembly
GZH44_RS01820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GZH44_RS01830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GZH44_RS01835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GZH44_RS01840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GZH44_RS01845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GZH44_RS01850	COG0768	penicillin binding
GZH44_RS01860	COG0275	rRNA processing
GZH44_RS01865	COG2001	Belongs to the MraZ family
GZH44_RS01875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GZH44_RS01880	COG2264	protein methyltransferase activity
GZH44_RS01890	COG0833	amino acid
GZH44_RS01900	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GZH44_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZH44_RS01910	COG1126	abc transporter atp-binding protein
GZH44_RS01915	COG0765	amino acid transport
GZH44_RS01935	COG1077	Cell shape determining protein MreB Mrl
GZH44_RS01940	COG2003	Belongs to the UPF0758 family
GZH44_RS01955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GZH44_RS01960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GZH44_RS01970	COG4120	Belongs to the binding-protein-dependent transport system permease family
GZH44_RS01985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZH44_RS01990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GZH44_RS02010	COG1388	LysM domain
GZH44_RS02020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GZH44_RS02030	COG0494	nUDIX hydrolase
GZH44_RS02035	COG1278	Cold shock
GZH44_RS02055	COG1705	Flagellar rod assembly protein muramidase FlgJ
GZH44_RS02055	COG3951	Flagellar rod assembly protein muramidase FlgJ
GZH44_RS02060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GZH44_RS02065	COG4988	ABC transporter
GZH44_RS02070	COG1294	oxidase, subunit
GZH44_RS02075	COG1271	oxidase subunit
GZH44_RS02190	COG2183	response to ionizing radiation
GZH44_RS02195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GZH44_RS02200	COG0586	Pfam SNARE associated Golgi protein
GZH44_RS02210	COG0194	GDP metabolic process
GZH44_RS02215	COG0497	DNA recombination
GZH44_RS02220	COG1438	arginine binding
GZH44_RS02225	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GZH44_RS02235	COG1722	exodeoxyribonuclease VII activity
GZH44_RS02240	COG1570	exodeoxyribonuclease VII activity
GZH44_RS02245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GZH44_RS02250	COG4720	Psort location CytoplasmicMembrane, score
GZH44_RS02260	COG0363	glucosamine-6-phosphate deaminase activity
GZH44_RS02265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GZH44_RS02270	COG0716	FMN binding
GZH44_RS02275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GZH44_RS02280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GZH44_RS02290	COG1323	Belongs to the UPF0348 family
GZH44_RS02300	COG0799	negative regulation of ribosome biogenesis
GZH44_RS02305	COG1713	HD superfamily hydrolase involved in NAD metabolism
GZH44_RS02310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GZH44_RS02320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GZH44_RS02330	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZH44_RS02340	COG0531	amino acid
GZH44_RS02345	COG0459	protein refolding
GZH44_RS02350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GZH44_RS02355	COG0488	(ABC) transporter
GZH44_RS02360	COG0285	dihydrofolate synthase activity
GZH44_RS02365	COG0525	valine-tRNA ligase activity
GZH44_RS02375	COG1272	protein, Hemolysin III
GZH44_RS02400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GZH44_RS02415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GZH44_RS02420	COG3557	Belongs to the UPF0374 family
GZH44_RS02435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GZH44_RS02440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GZH44_RS02445	COG0581	inorganic phosphate transmembrane transporter activity
GZH44_RS02450	COG0573	inorganic phosphate transmembrane transporter activity
GZH44_RS02470	COG0647	UMP catabolic process
GZH44_RS02475	COG4470	Protein conserved in bacteria
GZH44_RS02480	COG0737	Belongs to the 5'-nucleotidase family
GZH44_RS02495	COG0006	proline dipeptidase activity
GZH44_RS02500	COG4948	Mandelate Racemase Muconate Lactonizing
GZH44_RS02510	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GZH44_RS02515	COG1169	isochorismate synthase
GZH44_RS02520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GZH44_RS02525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GZH44_RS02555	COG0174	glutamine synthetase
GZH44_RS02560	COG0789	Transcriptional regulator
GZH44_RS02565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GZH44_RS02570	COG0584	glycerophosphoryl diester phosphodiesterase
GZH44_RS02590	COG1940	carbohydrate kinase activity
GZH44_RS02600	COG0705	Rhomboid family
GZH44_RS02605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GZH44_RS02610	COG0768	penicillin binding
GZH44_RS02620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GZH44_RS02625	COG0514	ATP-dependent DNA helicase (RecQ)
GZH44_RS02630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GZH44_RS02635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH44_RS02635	COG0072	phenylalanine-tRNA ligase activity
GZH44_RS02640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GZH44_RS02645	COG1733	regulation of RNA biosynthetic process
GZH44_RS02655	COG4975	Glucose uptake
GZH44_RS02665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZH44_RS02675	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GZH44_RS02690	COG4956	integral membrane protein (PIN domain superfamily)
GZH44_RS02700	COG0756	dUTP diphosphatase activity
GZH44_RS02710	COG0791	NLP P60 protein
GZH44_RS02715	COG3942	CHAP domain
GZH44_RS02715	COG1388	LysM domain
GZH44_RS02720	COG0542	response to heat
GZH44_RS02725	COG0604	alcohol dehydrogenase
GZH44_RS02730	COG3527	Alpha-acetolactate decarboxylase
GZH44_RS02735	COG0028	Belongs to the TPP enzyme family
GZH44_RS02765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GZH44_RS02770	COG0740	serine-type endopeptidase activity
GZH44_RS02775	COG1481	regulation of sporulation
GZH44_RS02780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GZH44_RS02785	COG1660	Displays ATPase and GTPase activities
GZH44_RS02795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GZH44_RS02820	COG1573	uracil-dna glycosylase
GZH44_RS02825	COG0366	Alpha amylase catalytic
GZH44_RS02845	COG3775	system Galactitol-specific IIC component
GZH44_RS02860	COG3711	transcriptional antiterminator
GZH44_RS02860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZH44_RS02870	COG0667	Aldo Keto reductase
GZH44_RS02875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GZH44_RS02910	COG2169	Transcriptional regulator
GZH44_RS02910	COG1917	Cupin 2, conserved barrel domain protein
GZH44_RS02920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GZH44_RS02925	COG0149	triose-phosphate isomerase activity
GZH44_RS02935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GZH44_RS02940	COG2186	Transcriptional regulator
GZH44_RS02945	COG2610	gluconate transmembrane transporter activity
GZH44_RS02950	COG0800	Aldolase
GZH44_RS02960	COG4948	Mandelate Racemase Muconate Lactonizing
GZH44_RS02975	COG4166	transmembrane transport
GZH44_RS02990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZH44_RS03010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GZH44_RS03015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GZH44_RS03020	COG0101	tRNA pseudouridine synthase activity
GZH44_RS03030	COG1122	ATPase activity
GZH44_RS03035	COG1122	ATPase activity
GZH44_RS03045	COG1252	NADH dehydrogenase
GZH44_RS03050	COG0803	Belongs to the bacterial solute-binding protein 9 family
GZH44_RS03055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GZH44_RS03060	COG1121	(ABC) transporter
GZH44_RS03070	COG0222	ribosome binding
GZH44_RS03075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GZH44_RS03080	COG0081	regulation of translation
GZH44_RS03085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GZH44_RS03090	COG0250	Participates in transcription elongation, termination and antitermination
GZH44_RS03100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GZH44_RS03110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZH44_RS03115	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GZH44_RS03120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GZH44_RS03125	COG0284	orotidine-5'-phosphate decarboxylase activity
GZH44_RS03130	COG0167	dihydroorotate dehydrogenase activity
GZH44_RS03135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GZH44_RS03140	COG0505	Belongs to the CarA family
GZH44_RS03150	COG0540	Belongs to the ATCase OTCase family
GZH44_RS03155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GZH44_RS03155	COG0517	IMP dehydrogenase activity
GZH44_RS03160	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GZH44_RS03165	COG1854	S-ribosylhomocysteine lyase activity
GZH44_RS03170	COG0215	cysteine-tRNA ligase activity
GZH44_RS03175	COG0667	Aldo Keto reductase
GZH44_RS03180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GZH44_RS03185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GZH44_RS03195	COG1464	Belongs to the NlpA lipoprotein family
GZH44_RS03200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GZH44_RS03225	COG0203	ribosomal protein L17
GZH44_RS03230	COG0202	RNA polymerase activity
GZH44_RS03235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GZH44_RS03240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GZH44_RS03245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GZH44_RS03250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GZH44_RS03255	COG0563	adenylate kinase activity
GZH44_RS03265	COG0200	Binds to the 23S rRNA
GZH44_RS03270	COG1841	ribosomal large subunit assembly
GZH44_RS03275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GZH44_RS03280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GZH44_RS03285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GZH44_RS03290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GZH44_RS03295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GZH44_RS03300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GZH44_RS03305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GZH44_RS03315	COG0255	Belongs to the universal ribosomal protein uL29 family
GZH44_RS03320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GZH44_RS03325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GZH44_RS03330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GZH44_RS03335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GZH44_RS03340	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GZH44_RS03345	COG0089	rRNA binding
GZH44_RS03355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GZH44_RS03360	COG0051	transcription antitermination factor activity, RNA binding
GZH44_RS03365	COG0142	geranyltranstransferase activity
GZH44_RS03370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GZH44_RS03385	COG1214	PFAM Peptidase M22, glycoprotease
GZH44_RS03390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GZH44_RS03410	COG3870	Protein conserved in bacteria
GZH44_RS03415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GZH44_RS03425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GZH44_RS03430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GZH44_RS03450	COG2813	Specifically methylates the guanine in position
GZH44_RS03460	COG0488	(ABC) transporter
GZH44_RS03470	COG0640	Transcriptional regulator
GZH44_RS03480	COG2814	Major facilitator Superfamily
GZH44_RS03485	COG1983	PspC domain protein
GZH44_RS03510	COG0500	methyltransferase
GZH44_RS03515	COG1979	alcohol dehydrogenase
GZH44_RS03520	COG1979	alcohol dehydrogenase
GZH44_RS03525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GZH44_RS03530	COG0085	RNA polymerase activity
GZH44_RS03535	COG0542	response to heat
GZH44_RS03540	COG4463	regulation of RNA biosynthetic process
GZH44_RS03565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GZH44_RS03570	COG1428	Deoxynucleoside kinase
GZH44_RS03580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GZH44_RS03585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GZH44_RS03590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GZH44_RS03595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GZH44_RS03600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GZH44_RS03605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GZH44_RS03610	COG0356	it plays a direct role in the translocation of protons across the membrane
GZH44_RS03615	COG2233	PERMEase
GZH44_RS03620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GZH44_RS03625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GZH44_RS03630	COG0009	L-threonylcarbamoyladenylate synthase
GZH44_RS03635	COG2890	protein-(glutamine-N5) methyltransferase activity
GZH44_RS03645	COG1435	thymidine kinase activity
GZH44_RS03650	COG3442	glutamine amidotransferase
GZH44_RS03655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GZH44_RS03660	COG1482	cell wall glycoprotein biosynthetic process
GZH44_RS03680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GZH44_RS03685	COG2252	PERMEase
GZH44_RS03690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GZH44_RS03700	COG1132	(ABC) transporter
GZH44_RS03705	COG1132	(ABC) transporter
GZH44_RS03715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GZH44_RS03720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GZH44_RS03725	COG2723	6-phospho-beta-galactosidase activity
GZH44_RS03730	COG1447	Phosphotransferase system cellobiose-specific component IIA
GZH44_RS03735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GZH44_RS03740	COG2723	6-phospho-beta-galactosidase activity
GZH44_RS03745	COG2188	Transcriptional regulator
GZH44_RS03750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GZH44_RS03755	COG0588	phosphoglycerate mutase activity
GZH44_RS03770	COG0708	Exodeoxyribonuclease III
GZH44_RS03775	COG1454	alcohol dehydrogenase
GZH44_RS03775	COG1012	belongs to the aldehyde dehydrogenase family
GZH44_RS03780	COG2217	Heavy metal translocating P-type atpase
GZH44_RS03800	COG3590	peptidase
GZH44_RS03810	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GZH44_RS03815	COG2188	Transcriptional regulator
GZH44_RS03820	COG1418	mRNA catabolic process
GZH44_RS03840	COG0765	amino acid transport
GZH44_RS03860	COG0656	L-ascorbic acid biosynthetic process
GZH44_RS03865	COG2160	L-arabinose isomerase activity
GZH44_RS03885	COG0534	Mate efflux family protein
GZH44_RS03895	COG0488	(ABC) transporter
GZH44_RS03905	COG1121	(ABC) transporter
GZH44_RS03920	COG2755	lipolytic protein G-D-S-L family
GZH44_RS03920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GZH44_RS03940	COG3104	oligopeptide transport
GZH44_RS03970	COG0671	phosphoesterase, PA-phosphatase related
GZH44_RS03980	COG0745	RESPONSE REGULATOR receiver
GZH44_RS03990	COG0012	GTP binding
GZH44_RS04000	COG1475	DNA binding
GZH44_RS04005	COG1192	Involved in chromosome partitioning
GZH44_RS04010	COG0357	Ribosomal RNA small subunit methyltransferase G
GZH44_RS04020	COG1194	a g-specific adenine glycosylase
GZH44_RS04030	COG5002	protein histidine kinase activity
GZH44_RS04035	COG0745	RESPONSE REGULATOR receiver
GZH44_RS04040	COG0531	amino acid
GZH44_RS04055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GZH44_RS04070	COG4443	Transcriptional Coactivator p15 (PC4)
GZH44_RS04075	COG0252	asparaginase activity
GZH44_RS04085	COG1113	amino acid transport
GZH44_RS04095	COG0531	amino acid
GZH44_RS04105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GZH44_RS04110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GZH44_RS04120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GZH44_RS04130	COG0477	Major facilitator Superfamily
GZH44_RS04135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZH44_RS04135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZH44_RS04150	COG3716	PTS system mannose fructose sorbose family IID component
GZH44_RS04165	COG2188	Transcriptional regulator
GZH44_RS04170	COG2188	Transcriptional regulator
GZH44_RS04175	COG0531	amino acid
GZH44_RS04190	COG2855	membrane
GZH44_RS04195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GZH44_RS04210	COG1012	belongs to the aldehyde dehydrogenase family
GZH44_RS04270	COG1113	amino acid transport
GZH44_RS04285	COG0628	permease
GZH44_RS04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZH44_RS04305	COG0765	amino acid transport
GZH44_RS04310	COG1126	abc transporter atp-binding protein
GZH44_RS04320	COG0656	L-ascorbic acid biosynthetic process
GZH44_RS04330	COG0436	Aminotransferase
GZH44_RS04335	COG0277	FAD linked oxidase domain protein
GZH44_RS04340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GZH44_RS04345	COG1122	ATPase activity
GZH44_RS04350	COG4720	Psort location CytoplasmicMembrane, score
GZH44_RS04355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GZH44_RS04360	COG2357	RelA SpoT domain protein
GZH44_RS04365	COG1744	ABC transporter substrate-binding protein PnrA-like
GZH44_RS04390	COG3048	D-serine ammonia-lyase activity
GZH44_RS04405	COG1136	(ABC) transporter
GZH44_RS04425	COG0789	Transcriptional regulator
GZH44_RS04430	COG0477	Major facilitator Superfamily
GZH44_RS04435	COG1827	regulation of RNA biosynthetic process
GZH44_RS04445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GZH44_RS04465	COG0402	S-adenosylhomocysteine deaminase activity
GZH44_RS04470	COG1268	BioY protein
GZH44_RS04485	COG1070	Carbohydrate kinase
GZH44_RS04500	COG2190	(PTS) system
GZH44_RS04500	COG2211	Major facilitator Superfamily
GZH44_RS04535	COG1609	Transcriptional regulator
GZH44_RS04540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GZH44_RS04545	COG1881	PFAM PEBP family protein
GZH44_RS04550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GZH44_RS04555	COG0436	Aminotransferase
GZH44_RS04560	COG0110	maltose O-acetyltransferase activity
GZH44_RS04565	COG0110	maltose O-acetyltransferase activity
GZH44_RS04570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GZH44_RS04580	COG0531	amino acid
GZH44_RS04605	COG2252	PERMEase
GZH44_RS04620	COG1131	(ABC) transporter
GZH44_RS04625	COG2186	Transcriptional regulator
GZH44_RS04630	COG0328	RNA-DNA hybrid ribonuclease activity
GZH44_RS04635	COG0561	phosphatase activity
GZH44_RS04640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GZH44_RS04660	COG0028	Belongs to the TPP enzyme family
GZH44_RS04675	COG4221	oxidoreductase activity
GZH44_RS04680	COG0789	Transcriptional regulator
GZH44_RS04685	COG1301	dicarboxylic acid transport
GZH44_RS04690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZH44_RS04695	COG2022	thiamine diphosphate biosynthetic process
GZH44_RS04700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GZH44_RS04720	COG1113	amino acid transport
GZH44_RS04725	COG0569	domain protein
GZH44_RS04730	COG5386	Cell surface protein
GZH44_RS04750	COG1120	ATPase activity
GZH44_RS04765	COG0706	membrane insertase activity
GZH44_RS04770	COG0594	ribonuclease P activity
GZH44_RS04775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GZH44_RS04780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GZH44_RS04785	COG0592	DNA-directed DNA polymerase activity
GZH44_RS04790	COG2501	S4 domain
GZH44_RS04795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GZH44_RS04800	COG0187	DNA topoisomerase II activity
GZH44_RS04815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GZH44_RS04820	COG2011	ABC-type metal ion transport system permease component
GZH44_RS04825	COG1464	Belongs to the NlpA lipoprotein family
GZH44_RS04835	COG2409	Drug exporters of the RND superfamily
GZH44_RS04850	COG1368	sulfuric ester hydrolase activity
GZH44_RS04870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GZH44_RS04905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH44_RS04905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH44_RS04910	COG0025	NhaP-type Na H and K H
GZH44_RS04915	COG0084	hydrolase, TatD family'
GZH44_RS04920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GZH44_RS04925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GZH44_RS04930	COG1253	flavin adenine dinucleotide binding
GZH44_RS04935	COG1253	flavin adenine dinucleotide binding
GZH44_RS04940	COG4466	Protein conserved in bacteria
GZH44_RS04945	COG2131	deaminase
GZH44_RS04955	COG1316	TRANSCRIPTIONal
GZH44_RS04985	COG0737	Belongs to the 5'-nucleotidase family
GZH44_RS05030	COG2814	Major facilitator Superfamily
GZH44_RS05040	COG1120	ATPase activity
GZH44_RS05055	COG0561	phosphatase activity
GZH44_RS05110	COG1511	domain protein
GZH44_RS05125	COG0193	aminoacyl-tRNA hydrolase activity
GZH44_RS05130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GZH44_RS05135	COG2244	polysaccharide biosynthetic process
GZH44_RS05140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GZH44_RS05165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GZH44_RS05170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GZH44_RS05500	COG1846	Transcriptional regulator
GZH44_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZH44_RS05510	COG0604	alcohol dehydrogenase
GZH44_RS05515	COG3759	membrane
GZH44_RS05525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GZH44_RS05550	COG0583	DNA-binding transcription factor activity
GZH44_RS05570	COG2261	transglycosylase associated protein
GZH44_RS05580	COG1737	Transcriptional regulator
GZH44_RS05585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GZH44_RS05595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GZH44_RS05600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GZH44_RS05610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH44_RS05615	COG1956	GAF domain-containing protein
GZH44_RS05625	COG2814	Major facilitator Superfamily
GZH44_RS05630	COG2233	PERMEase
GZH44_RS05635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GZH44_RS05640	COG2084	Dehydrogenase
GZH44_RS05645	COG0438	transferase activity, transferring glycosyl groups
GZH44_RS05710	COG1175	transmembrane transport
GZH44_RS05725	COG3250	beta-galactosidase activity
GZH44_RS05730	COG3842	ATPase activity
GZH44_RS05735	COG1250	3-hydroxyacyl-CoA dehydrogenase
GZH44_RS05740	COG0626	cystathionine gamma-synthase activity
GZH44_RS05745	COG1088	dTDP-glucose 4,6-dehydratase activity
GZH44_RS05750	COG4989	oxidoreductase activity
GZH44_RS05760	COG3764	Sortase (surface protein transpeptidase)
GZH44_RS05765	COG0702	epimerase
GZH44_RS05770	COG1733	regulation of RNA biosynthetic process
GZH44_RS05775	COG0693	protein deglycase activity
GZH44_RS05780	COG1609	Transcriptional regulator
GZH44_RS05785	COG1874	Beta-galactosidase
GZH44_RS05800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GZH44_RS05805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GZH44_RS05810	COG2376	Dihydroxyacetone kinase
GZH44_RS05815	COG1461	Dihydroxyacetone kinase
GZH44_RS05820	COG1737	Transcriptional regulator
GZH44_RS05825	COG1263	PTS System
GZH44_RS05825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZH44_RS05830	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GZH44_RS05835	COG0028	Belongs to the TPP enzyme family
GZH44_RS05860	COG2514	catechol 2,3-dioxygenase activity
GZH44_RS05865	COG0386	Belongs to the glutathione peroxidase family
GZH44_RS05870	COG1063	alcohol dehydrogenase
GZH44_RS05875	COG0431	NADPH-dependent FMN reductase
GZH44_RS05880	COG2807	transmembrane transport
GZH44_RS05885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GZH44_RS05915	COG0671	phosphoesterase, PA-phosphatase related
GZH44_RS05920	COG0495	leucyl-tRNA aminoacylation
GZH44_RS05930	COG2244	polysaccharide biosynthetic process
GZH44_RS05960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GZH44_RS05965	COG0531	amino acid
GZH44_RS05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZH44_RS05975	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GZH44_RS05980	COG1074	ATP-dependent DNA helicase activity
GZH44_RS05985	COG2814	Major facilitator Superfamily
GZH44_RS05990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GZH44_RS06000	COG1051	belongs to the nudix hydrolase family
GZH44_RS06005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GZH44_RS06015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GZH44_RS06025	COG0360	Binds together with S18 to 16S ribosomal RNA
GZH44_RS06030	COG0629	single-stranded DNA binding
GZH44_RS06035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GZH44_RS06055	COG0516	GMP reductase activity
GZH44_RS06055	COG0517	IMP dehydrogenase activity
GZH44_RS06060	COG0516	GMP reductase activity
GZH44_RS06060	COG0517	IMP dehydrogenase activity
GZH44_RS06070	COG0745	RESPONSE REGULATOR receiver
GZH44_RS06075	COG5002	protein histidine kinase activity
GZH44_RS06090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GZH44_RS06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZH44_RS06105	COG1078	dGTPase activity
GZH44_RS06110	COG0561	phosphatase activity
GZH44_RS06115	COG3343	RNA polymerase activity
GZH44_RS06120	COG0504	CTP synthase activity
GZH44_RS06125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GZH44_RS06140	COG2337	Toxic component of a toxin-antitoxin (TA) module
GZH44_RS06160	COG0673	inositol 2-dehydrogenase activity
GZH44_RS06165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GZH44_RS06175	COG0194	GDP metabolic process
GZH44_RS06195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZH44_RS06200	COG0765	amino acid transport
GZH44_RS06205	COG0765	amino acid transport
GZH44_RS06210	COG4166	transmembrane transport
GZH44_RS06215	COG0601	transmembrane transport
GZH44_RS06220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZH44_RS06225	COG0444	Belongs to the ABC transporter superfamily
GZH44_RS06230	COG4608	Belongs to the ABC transporter superfamily
GZH44_RS06240	COG0359	binds to the 23S rRNA
GZH44_RS06245	COG0305	Participates in initiation and elongation during chromosome replication
GZH44_RS06250	COG2814	Major facilitator Superfamily
GZH44_RS06255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZH44_RS06260	COG2832	Protein of unknown function (DUF454)
GZH44_RS06270	COG1744	ABC transporter substrate-binding protein PnrA-like
GZH44_RS06275	COG2814	Major facilitator Superfamily
GZH44_RS06285	COG0492	ferredoxin-NADP+ reductase activity
GZH44_RS06290	COG0588	phosphoglycerate mutase activity
GZH44_RS06340	COG1309	transcriptional regulator
GZH44_RS06350	COG1064	alcohol dehydrogenase
GZH44_RS06355	COG1609	Transcriptional regulator
GZH44_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
GZH44_RS06380	COG2610	gluconate transmembrane transporter activity
GZH44_RS06385	COG0628	permease
GZH44_RS06390	COG1744	ABC transporter substrate-binding protein PnrA-like
GZH44_RS06395	COG3845	ABC transporter
GZH44_RS06400	COG4603	Belongs to the binding-protein-dependent transport system permease family
GZH44_RS06405	COG1079	Belongs to the binding-protein-dependent transport system permease family
GZH44_RS06410	COG0561	phosphatase activity
GZH44_RS06415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GZH44_RS06420	COG1077	Cell shape determining protein MreB Mrl
GZH44_RS06430	COG0772	Belongs to the SEDS family
GZH44_RS06435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GZH44_RS06450	COG0561	phosphatase activity
GZH44_RS06455	COG0577	efflux transmembrane transporter activity
GZH44_RS06455	COG1136	(ABC) transporter
GZH44_RS06465	COG2188	Transcriptional regulator
GZH44_RS06470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GZH44_RS06475	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GZH44_RS06490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GZH44_RS06500	COG0640	Transcriptional regulator
GZH44_RS06510	COG2246	polysaccharide biosynthetic process
GZH44_RS06515	COG0561	phosphatase activity
GZH44_RS06520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GZH44_RS06525	COG4589	Belongs to the CDS family
GZH44_RS06530	COG0750	zinc metalloprotease
GZH44_RS06535	COG0442	prolyl-tRNA aminoacylation
GZH44_RS06540	COG2176	DNA-directed DNA polymerase activity
GZH44_RS06560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZH44_RS06595	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GZH44_RS06605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GZH44_RS06615	COG2183	response to ionizing radiation
GZH44_RS06645	COG2217	Heavy metal translocating P-type atpase
GZH44_RS06660	COG1136	(ABC) transporter
GZH44_RS06670	COG1940	carbohydrate kinase activity
GZH44_RS06720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GZH44_RS06725	COG1045	serine acetyltransferase
GZH44_RS06730	COG0582	viral genome integration into host DNA
GZH44_RS06735	COG3759	membrane
GZH44_RS06740	COG1396	sequence-specific DNA binding
GZH44_RS06795	COG2261	transglycosylase associated protein
GZH44_RS06805	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GZH44_RS06830	COG0516	GMP reductase activity
GZH44_RS06835	COG0668	transmembrane transport
GZH44_RS06850	COG0402	S-adenosylhomocysteine deaminase activity
GZH44_RS06855	COG0745	RESPONSE REGULATOR receiver
GZH44_RS06860	COG5002	protein histidine kinase activity
GZH44_RS06860	COG3850	Histidine kinase
GZH44_RS06865	COG2017	converts alpha-aldose to the beta-anomer
GZH44_RS06870	COG0166	Belongs to the GPI family
GZH44_RS06875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GZH44_RS06890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GZH44_RS06895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GZH44_RS06910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GZH44_RS06915	COG0049	tRNA binding
GZH44_RS06920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GZH44_RS06930	COG3842	ATPase activity
GZH44_RS06940	COG1177	transmembrane transport
GZH44_RS06960	COG0589	response to stress
GZH44_RS06975	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GZH44_RS06980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GZH44_RS06985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GZH44_RS06990	COG0492	ferredoxin-NADP+ reductase activity
GZH44_RS06995	COG0406	alpha-ribazole phosphatase activity
GZH44_RS07000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GZH44_RS07010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZH44_RS07020	COG0366	Alpha amylase catalytic
GZH44_RS07030	COG1175	transmembrane transport
GZH44_RS07035	COG3833	ABC-type maltose transport systems, permease component
GZH44_RS07040	COG3842	ATPase activity
GZH44_RS07050	COG0149	triose-phosphate isomerase activity
GZH44_RS07070	COG0557	exoribonuclease II activity
GZH44_RS07075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GZH44_RS07080	COG0765	amino acid transport
GZH44_RS07085	COG1126	abc transporter atp-binding protein
GZH44_RS07100	COG0280	phosphate acetyltransferase
GZH44_RS07110	COG0802	atpase or kinase
GZH44_RS07125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GZH44_RS07130	COG0025	NhaP-type Na H and K H
GZH44_RS07140	COG4856	YbbR-like protein
GZH44_RS07145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GZH44_RS07155	COG0438	transferase activity, transferring glycosyl groups
GZH44_RS07160	COG0438	transferase activity, transferring glycosyl groups
GZH44_RS07175	COG1368	sulfuric ester hydrolase activity
GZH44_RS07240	COG3715	PTS system
GZH44_RS07245	COG3716	PTS system mannose fructose sorbose family IID component
GZH44_RS07255	COG0588	phosphoglycerate mutase activity
GZH44_RS07290	COG0126	phosphoglycerate kinase activity
GZH44_RS07305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GZH44_RS07315	COG0517	IMP dehydrogenase activity
GZH44_RS07315	COG1125	glycine betaine transport
GZH44_RS07320	COG1174	glycine betaine transport
GZH44_RS07325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZH44_RS07360	COG1396	sequence-specific DNA binding
GZH44_RS07420	COG1396	sequence-specific DNA binding
GZH44_RS07445	COG0629	single-stranded DNA binding
GZH44_RS07495	COG5484	DNA packaging
GZH44_RS07615	COG1757	Na H antiporter
GZH44_RS07620	COG0328	RNA-DNA hybrid ribonuclease activity
GZH44_RS07630	COG0564	pseudouridine synthase activity
GZH44_RS07635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GZH44_RS07640	COG0505	Belongs to the CarA family
GZH44_RS07650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZH44_RS07655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GZH44_RS07700	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GZH44_RS07705	COG2267	carboxylic ester hydrolase activity
GZH44_RS07715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GZH44_RS07720	COG1846	Transcriptional regulator
GZH44_RS07725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GZH44_RS07730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GZH44_RS07735	COG2070	2-Nitropropane dioxygenase
GZH44_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
GZH44_RS07750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GZH44_RS07765	COG0439	Biotin carboxylase
GZH44_RS07780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GZH44_RS07785	COG1704	LemA family
GZH44_RS07790	COG0501	Belongs to the peptidase M48B family
GZH44_RS07795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GZH44_RS07800	COG1335	isochorismatase
GZH44_RS07805	COG0673	inositol 2-dehydrogenase activity
GZH44_RS07810	COG0513	Belongs to the DEAD box helicase family
GZH44_RS07815	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GZH44_RS07820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GZH44_RS07820	COG1321	iron dependent repressor
GZH44_RS07845	COG0527	aspartate kinase activity
GZH44_RS07850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GZH44_RS07855	COG0019	diaminopimelate decarboxylase activity
GZH44_RS07860	COG2171	N-acyltransferase activity
GZH44_RS07865	COG1473	amidohydrolase
GZH44_RS07870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GZH44_RS07880	COG0436	Aminotransferase
GZH44_RS07885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GZH44_RS07895	COG0436	Aminotransferase
GZH44_RS07900	COG4684	Psort location CytoplasmicMembrane, score
GZH44_RS07915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GZH44_RS07920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GZH44_RS07925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GZH44_RS07930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GZH44_RS07935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GZH44_RS07940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GZH44_RS07945	COG0710	3-dehydroquinate dehydratase activity
GZH44_RS07960	COG1122	ATPase activity
GZH44_RS07965	COG4721	ABC-type cobalt transport system, permease component
GZH44_RS07970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GZH44_RS07975	COG0667	Aldo Keto reductase
GZH44_RS07980	COG4807	Protein conserved in bacteria
GZH44_RS07985	COG1914	H( )-stimulated, divalent metal cation uptake system
GZH44_RS08005	COG2936	dipeptidyl-peptidase activity
GZH44_RS08010	COG0561	phosphatase activity
GZH44_RS08015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GZH44_RS08020	COG0154	amidase activity
GZH44_RS08025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GZH44_RS08030	COG1597	lipid kinase activity
GZH44_RS08055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GZH44_RS08080	COG0285	dihydrofolate synthase activity
GZH44_RS08085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GZH44_RS08100	COG0018	arginyl-trna synthetase
GZH44_RS08105	COG1438	arginine binding
GZH44_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GZH44_RS08115	COG3679	Belongs to the UPF0342 family
GZH44_RS08125	COG4717	serine-type aminopeptidase activity
GZH44_RS08130	COG3481	metal-dependent phosphohydrolase, HD sub domain
GZH44_RS08135	COG1070	Carbohydrate kinase
GZH44_RS08140	COG3402	PFAM membrane-flanked domain
GZH44_RS08160	COG2610	gluconate transmembrane transporter activity
GZH44_RS08170	COG0612	Peptidase, M16
GZH44_RS08175	COG1426	Protein conserved in bacteria
GZH44_RS08180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GZH44_RS08185	COG1546	Belongs to the CinA family
GZH44_RS08185	COG1058	Belongs to the CinA family
GZH44_RS08190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GZH44_RS08195	COG3973	AAA domain
GZH44_RS08205	COG1388	LysM domain
GZH44_RS08210	COG2814	Major facilitator Superfamily
GZH44_RS08220	COG1278	Cold shock
GZH44_RS08225	COG0564	pseudouridine synthase activity
GZH44_RS08235	COG2309	aminopeptidase activity
GZH44_RS08260	COG0393	Putative heavy-metal-binding
GZH44_RS08265	COG3475	LICD family
GZH44_RS08275	COG1134	teichoic acid transport
GZH44_RS08275	COG1388	LysM domain
GZH44_RS08280	COG1682	transport, permease protein
GZH44_RS08295	COG0463	Glycosyl transferase, family 2
GZH44_RS08295	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GZH44_RS08300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GZH44_RS08330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GZH44_RS08335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GZH44_RS08335	COG1215	transferase activity, transferring glycosyl groups
GZH44_RS08365	COG1501	Belongs to the glycosyl hydrolase 31 family
GZH44_RS08385	COG0366	Alpha amylase catalytic
GZH44_RS08385	COG5263	repeat protein
GZH44_RS08390	COG0024	Methionine aminopeptidase
GZH44_RS08415	COG0562	UDP-galactopyranose mutase
GZH44_RS08430	COG0463	Glycosyl transferase, family 2
GZH44_RS08435	COG1216	Glycosyl transferase, family 2
GZH44_RS08455	COG1420	regulation of RNA biosynthetic process
GZH44_RS08465	COG0443	Heat shock 70 kDa protein
GZH44_RS08470	COG0484	heat shock protein binding
GZH44_RS08485	COG1234	tRNA 3'-trailer cleavage
GZH44_RS08490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GZH44_RS08490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GZH44_RS08495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GZH44_RS08515	COG1368	sulfuric ester hydrolase activity
GZH44_RS08540	COG0110	maltose O-acetyltransferase activity
GZH44_RS08545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GZH44_RS08550	COG4224	UPF0291 protein
GZH44_RS08555	COG3763	UPF0154 protein
GZH44_RS08560	COG0204	Acyl-transferase
GZH44_RS08565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GZH44_RS08570	COG2827	Endonuclease containing a URI domain
GZH44_RS08575	COG0052	Belongs to the universal ribosomal protein uS2 family
GZH44_RS08580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GZH44_RS08600	COG0004	ammonium transporteR
GZH44_RS08605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GZH44_RS08615	COG0617	tRNA 3'-terminal CCA addition
GZH44_RS08620	COG0488	(ABC) transporter
GZH44_RS08635	COG0587	DNA-directed DNA polymerase activity
GZH44_RS08640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GZH44_RS08645	COG1490	D-aminoacyl-tRNA deacylase activity
GZH44_RS08655	COG0475	glutathione-regulated potassium exporter activity
GZH44_RS08665	COG2996	Protein conserved in bacteria
GZH44_RS08680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GZH44_RS08685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GZH44_RS08690	COG1187	pseudouridine synthase activity
GZH44_RS08695	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GZH44_RS08705	COG0514	ATP-dependent DNA helicase (RecQ)
GZH44_RS08715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GZH44_RS08720	COG0539	negative regulation of cytoplasmic translation
GZH44_RS08725	COG1160	GTP binding
GZH44_RS08735	COG0351	phosphomethylpyrimidine kinase
GZH44_RS08740	COG4720	Psort location CytoplasmicMembrane, score
GZH44_RS08745	COG2807	transmembrane transport
GZH44_RS08750	COG0420	3'-5' exonuclease activity
GZH44_RS08755	COG0419	ATPase involved in DNA repair
GZH44_RS08775	COG0457	Tetratricopeptide repeat
GZH44_RS08780	COG2384	SAM-dependent methyltransferase
GZH44_RS08785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GZH44_RS08790	COG2195	Cleaves the N-terminal amino acid of tripeptides
GZH44_RS08800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GZH44_RS08810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GZH44_RS08815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GZH44_RS08820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GZH44_RS08855	COG2169	Transcriptional regulator
GZH44_RS08860	COG2190	(PTS) system
GZH44_RS08860	COG2211	Major facilitator Superfamily
GZH44_RS08870	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GZH44_RS08880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZH44_RS08885	COG4708	membrane
GZH44_RS08890	COG0481	GTPase activity
GZH44_RS08920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GZH44_RS08925	COG0277	FAD linked oxidase domain protein
GZH44_RS08960	COG0588	phosphoglycerate mutase activity
GZH44_RS08965	COG1464	Belongs to the NlpA lipoprotein family
GZH44_RS08975	COG0071	Belongs to the small heat shock protein (HSP20) family
GZH44_RS08980	COG0561	phosphatase activity
GZH44_RS08995	COG3022	response to hydroperoxide
GZH44_RS09000	COG0406	alpha-ribazole phosphatase activity
GZH44_RS09020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GZH44_RS09030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GZH44_RS09040	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GZH44_RS09045	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GZH44_RS09050	COG0047	phosphoribosylformylglycinamidine synthase activity
GZH44_RS09055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GZH44_RS09070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GZH44_RS09075	COG0138	bifunctional purine biosynthesis protein purh
GZH44_RS09080	COG0151	Belongs to the GarS family
GZH44_RS09110	COG1609	Transcriptional regulator
GZH44_RS09120	COG0366	Alpha amylase catalytic
GZH44_RS09130	COG2223	nitrite transmembrane transporter activity
GZH44_RS09140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GZH44_RS09145	COG0351	phosphomethylpyrimidine kinase
GZH44_RS09160	COG1397	ADP-ribosylglycohydrolase
GZH44_RS09165	COG1719	4-vinyl reductase, 4VR
GZH44_RS09170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GZH44_RS09180	COG1131	(ABC) transporter
GZH44_RS09185	COG0537	adenosine 5'-monophosphoramidase activity
GZH44_RS09195	COG0556	nucleotide-excision repair
GZH44_RS09210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GZH44_RS09220	COG0116	Belongs to the methyltransferase superfamily
GZH44_RS09230	COG3599	regulation of cell shape
GZH44_RS09235	COG4474	Belongs to the UPF0398 family
GZH44_RS09240	COG3331	DNA recombination
GZH44_RS09250	COG3935	DnaD domain protein
GZH44_RS09255	COG0017	Asparaginyl-tRNA synthetase
GZH44_RS09265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZH44_RS09265	COG1199	ATP-dependent helicase activity
GZH44_RS09270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GZH44_RS09285	COG1304	FMN binding
GZH44_RS09295	COG0706	membrane insertase activity
GZH44_RS09305	COG5002	protein histidine kinase activity
GZH44_RS09310	COG0745	RESPONSE REGULATOR receiver
GZH44_RS09325	COG1484	DNA-dependent DNA replication
GZH44_RS09335	COG0237	dephospho-CoA kinase activity
GZH44_RS09340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GZH44_RS09365	COG0693	protein deglycase activity
GZH44_RS09380	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GZH44_RS09385	COG1733	regulation of RNA biosynthetic process
GZH44_RS09390	COG0702	epimerase
GZH44_RS09420	COG0783	Belongs to the Dps family
GZH44_RS09425	COG1250	3-hydroxyacyl-CoA dehydrogenase
GZH44_RS09440	COG2274	protein secretion by the type I secretion system
GZH44_RS09440	COG3271	cysteine-type peptidase activity
GZH44_RS09450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GZH44_RS09475	COG0668	transmembrane transport
GZH44_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
GZH44_RS09540	COG4619	ABC transporter
GZH44_RS09545	COG0390	transport system, permease component
GZH44_RS09565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZH44_RS09570	COG0783	Belongs to the Dps family
GZH44_RS09595	COG0604	alcohol dehydrogenase
GZH44_RS09645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GZH44_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
GZH44_RS09665	COG2801	Transposase and inactivated derivatives