locus-tag	class	description
FOL01_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOL01_RS00010	COG0592	DNA-directed DNA polymerase activity
FOL01_RS00015	COG2501	S4 domain
FOL01_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOL01_RS00025	COG0187	DNA topoisomerase II activity
FOL01_RS00035	COG4690	dipeptidase activity
FOL01_RS00050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_RS00055	COG2011	ABC-type metal ion transport system permease component
FOL01_RS00060	COG1464	Belongs to the NlpA lipoprotein family
FOL01_RS00070	COG2409	Drug exporters of the RND superfamily
FOL01_RS00090	COG1368	sulfuric ester hydrolase activity
FOL01_RS00110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOL01_RS00140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_RS00140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_RS00145	COG0025	NhaP-type Na H and K H
FOL01_RS00155	COG0084	hydrolase, TatD family'
FOL01_RS00160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOL01_RS00165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOL01_RS00170	COG1253	flavin adenine dinucleotide binding
FOL01_RS00175	COG1253	flavin adenine dinucleotide binding
FOL01_RS00185	COG2131	deaminase
FOL01_RS00195	COG1316	TRANSCRIPTIONal
FOL01_RS00205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOL01_RS00220	COG0737	Belongs to the 5'-nucleotidase family
FOL01_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS00265	COG5039	Polysaccharide pyruvyl transferase
FOL01_RS00270	COG0783	Belongs to the Dps family
FOL01_RS00285	COG1811	Na channel or pump
FOL01_RS00290	COG1983	PspC domain protein
FOL01_RS00310	COG2818	Glycosylase
FOL01_RS00320	COG1388	LysM domain
FOL01_RS00320	COG1134	teichoic acid transport
FOL01_RS00325	COG0477	Major facilitator Superfamily
FOL01_RS00340	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
FOL01_RS00350	COG4608	Belongs to the ABC transporter superfamily
FOL01_RS00355	COG0601	transmembrane transport
FOL01_RS00360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOL01_RS00375	COG1902	pentaerythritol trinitrate reductase activity
FOL01_RS00395	COG1309	transcriptional regulator
FOL01_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS00415	COG1131	(ABC) transporter
FOL01_RS00420	COG1131	(ABC) transporter
FOL01_RS00430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOL01_RS00435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_RS00440	COG1611	Belongs to the LOG family
FOL01_RS00445	COG1309	transcriptional regulator
FOL01_RS00455	COG1902	pentaerythritol trinitrate reductase activity
FOL01_RS00465	COG1247	-acetyltransferase
FOL01_RS00470	COG0561	phosphatase activity
FOL01_RS00475	COG1609	Transcriptional regulator
FOL01_RS00480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOL01_RS00500	COG0084	hydrolase, TatD family'
FOL01_RS00510	COG1309	transcriptional regulator
FOL01_RS00515	COG1511	domain protein
FOL01_RS00535	COG0193	aminoacyl-tRNA hydrolase activity
FOL01_RS00540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOL01_RS00545	COG2244	polysaccharide biosynthetic process
FOL01_RS00550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOL01_RS00575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOL01_RS00580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOL01_RS00810	COG0228	four-way junction DNA binding
FOL01_RS00905	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOL01_RS00930	COG1846	Transcriptional regulator
FOL01_RS00935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_RS00940	COG0604	alcohol dehydrogenase
FOL01_RS00945	COG3759	membrane
FOL01_RS00955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOL01_RS00985	COG2261	transglycosylase associated protein
FOL01_RS00995	COG1737	Transcriptional regulator
FOL01_RS01000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOL01_RS01010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOL01_RS01015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOL01_RS01025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOL01_RS01030	COG1956	GAF domain-containing protein
FOL01_RS01040	COG2814	Major facilitator Superfamily
FOL01_RS01045	COG2233	PERMEase
FOL01_RS01050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOL01_RS01055	COG2084	Dehydrogenase
FOL01_RS01060	COG0438	transferase activity, transferring glycosyl groups
FOL01_RS01095	COG0656	L-ascorbic acid biosynthetic process
FOL01_RS01100	COG2271	Major facilitator Superfamily
FOL01_RS01110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOL01_RS01155	COG0626	cystathionine gamma-synthase activity
FOL01_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOL01_RS01165	COG1088	dTDP-glucose 4,6-dehydratase activity
FOL01_RS01170	COG4989	oxidoreductase activity
FOL01_RS01180	COG0693	protein deglycase activity
FOL01_RS01185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOL01_RS01195	COG0149	triose-phosphate isomerase activity
FOL01_RS01200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOL01_RS01205	COG1609	Transcriptional regulator
FOL01_RS01210	COG1874	Beta-galactosidase
FOL01_RS01220	COG1733	regulation of RNA biosynthetic process
FOL01_RS01225	COG0693	protein deglycase activity
FOL01_RS01230	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_RS01250	COG1175	transmembrane transport
FOL01_RS01255	COG3833	ABC-type maltose transport systems, permease component
FOL01_RS01265	COG3250	beta-galactosidase activity
FOL01_RS01285	COG3842	ATPase activity
FOL01_RS01295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOL01_RS01315	COG1737	Transcriptional regulator
FOL01_RS01320	COG1263	PTS System
FOL01_RS01320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOL01_RS01325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOL01_RS01330	COG0028	Belongs to the TPP enzyme family
FOL01_RS01355	COG2514	catechol 2,3-dioxygenase activity
FOL01_RS01360	COG0386	Belongs to the glutathione peroxidase family
FOL01_RS01365	COG1063	alcohol dehydrogenase
FOL01_RS01370	COG0431	NADPH-dependent FMN reductase
FOL01_RS01375	COG2807	transmembrane transport
FOL01_RS01385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_RS01395	COG0671	phosphoesterase, PA-phosphatase related
FOL01_RS01400	COG0495	leucyl-tRNA aminoacylation
FOL01_RS01410	COG2244	polysaccharide biosynthetic process
FOL01_RS01435	COG0460	homoserine dehydrogenase
FOL01_RS01455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOL01_RS01460	COG0531	amino acid
FOL01_RS01465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_RS01470	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOL01_RS01475	COG1074	ATP-dependent DNA helicase activity
FOL01_RS01485	COG2814	Major facilitator Superfamily
FOL01_RS01500	COG1051	belongs to the nudix hydrolase family
FOL01_RS01505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOL01_RS01515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOL01_RS01520	COG1957	nucleoside hydrolase
FOL01_RS01525	COG0360	Binds together with S18 to 16S ribosomal RNA
FOL01_RS01530	COG0629	single-stranded DNA binding
FOL01_RS01535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOL01_RS01545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOL01_RS01555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOL01_RS01560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOL01_RS01565	COG0047	phosphoribosylformylglycinamidine synthase activity
FOL01_RS01570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOL01_RS01585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOL01_RS01590	COG0138	bifunctional purine biosynthesis protein purh
FOL01_RS01595	COG0151	Belongs to the GarS family
FOL01_RS01610	COG0517	IMP dehydrogenase activity
FOL01_RS01610	COG0516	GMP reductase activity
FOL01_RS01615	COG0516	GMP reductase activity
FOL01_RS01615	COG0517	IMP dehydrogenase activity
FOL01_RS01625	COG0745	RESPONSE REGULATOR receiver
FOL01_RS01630	COG5002	protein histidine kinase activity
FOL01_RS01645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOL01_RS01650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOL01_RS01660	COG1078	dGTPase activity
FOL01_RS01675	COG0504	CTP synthase activity
FOL01_RS01680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOL01_RS01690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOL01_RS01695	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOL01_RS01700	COG3973	AAA domain
FOL01_RS01705	COG0180	Tryptophanyl-tRNA synthetase
FOL01_RS01720	COG0673	inositol 2-dehydrogenase activity
FOL01_RS01725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOL01_RS01735	COG0194	GDP metabolic process
FOL01_RS01750	COG1126	abc transporter atp-binding protein
FOL01_RS01755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_RS01760	COG0765	amino acid transport
FOL01_RS01765	COG0765	amino acid transport
FOL01_RS01770	COG4166	transmembrane transport
FOL01_RS01775	COG0601	transmembrane transport
FOL01_RS01780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOL01_RS01785	COG0444	Belongs to the ABC transporter superfamily
FOL01_RS01790	COG4608	Belongs to the ABC transporter superfamily
FOL01_RS01800	COG0359	binds to the 23S rRNA
FOL01_RS01805	COG0305	Participates in initiation and elongation during chromosome replication
FOL01_RS01815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOL01_RS01820	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_RS01835	COG0492	ferredoxin-NADP+ reductase activity
FOL01_RS01840	COG0588	phosphoglycerate mutase activity
FOL01_RS01855	COG2610	gluconate transmembrane transporter activity
FOL01_RS01900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOL01_RS01905	COG1064	alcohol dehydrogenase
FOL01_RS01920	COG0628	permease
FOL01_RS01925	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_RS01930	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_RS01935	COG3845	ABC transporter
FOL01_RS01940	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOL01_RS01945	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOL01_RS01950	COG0561	phosphatase activity
FOL01_RS01955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOL01_RS01960	COG1077	Cell shape determining protein MreB Mrl
FOL01_RS01970	COG0772	Belongs to the SEDS family
FOL01_RS02005	COG0561	phosphatase activity
FOL01_RS02010	COG1136	(ABC) transporter
FOL01_RS02010	COG0577	efflux transmembrane transporter activity
FOL01_RS02020	COG2188	Transcriptional regulator
FOL01_RS02025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOL01_RS02030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FOL01_RS02035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOL01_RS02040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOL01_RS02045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOL01_RS02065	COG2246	polysaccharide biosynthetic process
FOL01_RS02070	COG0561	phosphatase activity
FOL01_RS02075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOL01_RS02080	COG4589	Belongs to the CDS family
FOL01_RS02085	COG0750	zinc metalloprotease
FOL01_RS02090	COG0442	prolyl-tRNA aminoacylation
FOL01_RS02095	COG2176	DNA-directed DNA polymerase activity
FOL01_RS02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_RS02155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOL01_RS02165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOL01_RS02175	COG2183	response to ionizing radiation
FOL01_RS02185	COG0561	phosphatase activity
FOL01_RS02210	COG2217	Heavy metal translocating P-type atpase
FOL01_RS02225	COG1136	(ABC) transporter
FOL01_RS02230	COG0577	efflux transmembrane transporter activity
FOL01_RS02245	COG1968	undecaprenyl-diphosphatase activity
FOL01_RS02310	COG0582	viral genome integration into host DNA
FOL01_RS02330	COG2932	Transcriptional regulator
FOL01_RS02360	COG1396	sequence-specific DNA binding
FOL01_RS02365	COG1396	sequence-specific DNA binding
FOL01_RS02385	COG0629	single-stranded DNA binding
FOL01_RS02435	COG1475	DNA binding
FOL01_RS02585	COG0668	transmembrane transport
FOL01_RS02600	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_RS02605	COG0745	RESPONSE REGULATOR receiver
FOL01_RS02610	COG3850	Histidine kinase
FOL01_RS02610	COG5002	protein histidine kinase activity
FOL01_RS02620	COG2017	converts alpha-aldose to the beta-anomer
FOL01_RS02630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOL01_RS02645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOL01_RS02650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOL01_RS02655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOL01_RS02665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOL01_RS02670	COG0049	tRNA binding
FOL01_RS02675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOL01_RS02680	COG3842	ATPase activity
FOL01_RS02685	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOL01_RS02690	COG1177	transmembrane transport
FOL01_RS02700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOL01_RS02710	COG2801	Transposase and inactivated derivatives
FOL01_RS02730	COG1950	PFAM Membrane protein of
FOL01_RS02735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOL01_RS02740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOL01_RS02750	COG0492	ferredoxin-NADP+ reductase activity
FOL01_RS02755	COG0406	alpha-ribazole phosphatase activity
FOL01_RS02760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOL01_RS02785	COG0149	triose-phosphate isomerase activity
FOL01_RS02795	COG0148	phosphopyruvate hydratase activity
FOL01_RS02805	COG0557	exoribonuclease II activity
FOL01_RS02810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOL01_RS02815	COG0765	amino acid transport
FOL01_RS02820	COG1126	abc transporter atp-binding protein
FOL01_RS02830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOL01_RS02835	COG0280	phosphate acetyltransferase
FOL01_RS02845	COG0802	atpase or kinase
FOL01_RS02855	COG2176	DNA-directed DNA polymerase activity
FOL01_RS02860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOL01_RS02875	COG4856	YbbR-like protein
FOL01_RS02890	COG0438	transferase activity, transferring glycosyl groups
FOL01_RS02895	COG0438	transferase activity, transferring glycosyl groups
FOL01_RS02910	COG1368	sulfuric ester hydrolase activity
FOL01_RS02970	COG3715	PTS system
FOL01_RS02975	COG3716	PTS system mannose fructose sorbose family IID component
FOL01_RS03015	COG1869	D-ribose catabolic process
FOL01_RS03020	COG4975	Glucose uptake
FOL01_RS03035	COG2843	Capsule synthesis protein
FOL01_RS03040	COG1464	Belongs to the NlpA lipoprotein family
FOL01_RS03050	COG1473	amidohydrolase
FOL01_RS03055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_RS03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_RS03070	COG0765	amino acid transport
FOL01_RS03075	COG1126	abc transporter atp-binding protein
FOL01_RS03115	COG0126	phosphoglycerate kinase activity
FOL01_RS03130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOL01_RS03145	COG1174	glycine betaine transport
FOL01_RS03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOL01_RS03175	COG1757	Na H antiporter
FOL01_RS03180	COG0328	RNA-DNA hybrid ribonuclease activity
FOL01_RS03190	COG0564	pseudouridine synthase activity
FOL01_RS03200	COG0505	Belongs to the CarA family
FOL01_RS03210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOL01_RS03215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOL01_RS03225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOL01_RS03235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOL01_RS03240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOL01_RS03255	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS03260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOL01_RS03275	COG0439	Biotin carboxylase
FOL01_RS03280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOL01_RS03295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOL01_RS03300	COG1704	LemA family
FOL01_RS03305	COG0501	Belongs to the peptidase M48B family
FOL01_RS03315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_RS03320	COG0673	inositol 2-dehydrogenase activity
FOL01_RS03325	COG0513	Belongs to the DEAD box helicase family
FOL01_RS03330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOL01_RS03335	COG1321	iron dependent repressor
FOL01_RS03335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOL01_RS03345	COG4720	Psort location CytoplasmicMembrane, score
FOL01_RS03350	COG1609	Transcriptional regulator
FOL01_RS03360	COG4166	transmembrane transport
FOL01_RS03365	COG0527	aspartate kinase activity
FOL01_RS03370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOL01_RS03380	COG2171	N-acyltransferase activity
FOL01_RS03385	COG1473	amidohydrolase
FOL01_RS03390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOL01_RS03400	COG0436	Aminotransferase
FOL01_RS03405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOL01_RS03415	COG0436	Aminotransferase
FOL01_RS03420	COG4684	Psort location CytoplasmicMembrane, score
FOL01_RS03435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOL01_RS03440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOL01_RS03445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOL01_RS03450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOL01_RS03455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOL01_RS03460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOL01_RS03465	COG0710	3-dehydroquinate dehydratase activity
FOL01_RS03475	COG4166	transmembrane transport
FOL01_RS03480	COG1228	amidohydrolase
FOL01_RS03490	COG1122	ATPase activity
FOL01_RS03495	COG4721	ABC-type cobalt transport system, permease component
FOL01_RS03500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOL01_RS03505	COG0667	Aldo Keto reductase
FOL01_RS03520	COG1914	H( )-stimulated, divalent metal cation uptake system
FOL01_RS03550	COG2936	dipeptidyl-peptidase activity
FOL01_RS03560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOL01_RS03560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOL01_RS03565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOL01_RS03570	COG0154	amidase activity
FOL01_RS03575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOL01_RS03580	COG1597	lipid kinase activity
FOL01_RS03585	COG0285	dihydrofolate synthase activity
FOL01_RS03605	COG0018	arginyl-trna synthetase
FOL01_RS03610	COG1438	arginine binding
FOL01_RS03615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOL01_RS03620	COG3679	Belongs to the UPF0342 family
FOL01_RS03625	COG0420	3'-5' exonuclease activity
FOL01_RS03630	COG4717	serine-type aminopeptidase activity
FOL01_RS03640	COG1070	Carbohydrate kinase
FOL01_RS03650	COG1215	transferase activity, transferring glycosyl groups
FOL01_RS03665	COG3402	PFAM membrane-flanked domain
FOL01_RS03670	COG3428	Bacterial PH domain
FOL01_RS03675	COG1704	LemA family
FOL01_RS03690	COG2801	Transposase and inactivated derivatives
FOL01_RS03705	COG0612	Peptidase, M16
FOL01_RS03710	COG1426	Protein conserved in bacteria
FOL01_RS03715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOL01_RS03720	COG1546	Belongs to the CinA family
FOL01_RS03720	COG1058	Belongs to the CinA family
FOL01_RS03725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOL01_RS03730	COG3973	AAA domain
FOL01_RS03740	COG0741	lytic transglycosylase activity
FOL01_RS03745	COG2814	Major facilitator Superfamily
FOL01_RS03755	COG1278	Cold shock
FOL01_RS03760	COG0564	pseudouridine synthase activity
FOL01_RS03770	COG2309	aminopeptidase activity
FOL01_RS03780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOL01_RS03800	COG0393	Putative heavy-metal-binding
FOL01_RS03805	COG3475	LICD family
FOL01_RS03815	COG1388	LysM domain
FOL01_RS03815	COG1134	teichoic acid transport
FOL01_RS03820	COG1682	transport, permease protein
FOL01_RS03835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_RS03840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOL01_RS03865	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_RS03870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_RS03870	COG1215	transferase activity, transferring glycosyl groups
FOL01_RS03900	COG1609	Transcriptional regulator
FOL01_RS03915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOL01_RS03920	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOL01_RS03925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOL01_RS03975	COG0024	Methionine aminopeptidase
FOL01_RS04000	COG0562	UDP-galactopyranose mutase
FOL01_RS04015	COG0463	Glycosyl transferase, family 2
FOL01_RS04020	COG1216	Glycosyl transferase, family 2
FOL01_RS04040	COG1420	regulation of RNA biosynthetic process
FOL01_RS04050	COG0443	Heat shock 70 kDa protein
FOL01_RS04055	COG0484	heat shock protein binding
FOL01_RS04070	COG1234	tRNA 3'-trailer cleavage
FOL01_RS04075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOL01_RS04075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOL01_RS04105	COG1285	pathogenesis
FOL01_RS04110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOL01_RS04115	COG4224	UPF0291 protein
FOL01_RS04120	COG3763	UPF0154 protein
FOL01_RS04125	COG0204	Acyl-transferase
FOL01_RS04130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOL01_RS04135	COG2827	Endonuclease containing a URI domain
FOL01_RS04140	COG0052	Belongs to the universal ribosomal protein uS2 family
FOL01_RS04145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOL01_RS04165	COG0004	ammonium transporteR
FOL01_RS04170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOL01_RS04180	COG0617	tRNA 3'-terminal CCA addition
FOL01_RS04185	COG0488	(ABC) transporter
FOL01_RS04200	COG0587	DNA-directed DNA polymerase activity
FOL01_RS04205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOL01_RS04210	COG1490	D-aminoacyl-tRNA deacylase activity
FOL01_RS04220	COG0475	glutathione-regulated potassium exporter activity
FOL01_RS04230	COG2996	Protein conserved in bacteria
FOL01_RS04245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOL01_RS04250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOL01_RS04255	COG1187	pseudouridine synthase activity
FOL01_RS04260	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOL01_RS04270	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_RS04280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOL01_RS04285	COG0539	negative regulation of cytoplasmic translation
FOL01_RS04290	COG1160	GTP binding
FOL01_RS04300	COG0351	phosphomethylpyrimidine kinase
FOL01_RS04305	COG4720	Psort location CytoplasmicMembrane, score
FOL01_RS04310	COG0420	3'-5' exonuclease activity
FOL01_RS04315	COG0419	ATPase involved in DNA repair
FOL01_RS04330	COG0457	Tetratricopeptide repeat
FOL01_RS04335	COG2384	SAM-dependent methyltransferase
FOL01_RS04340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOL01_RS04355	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOL01_RS04365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOL01_RS04370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOL01_RS04375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOL01_RS04390	COG1917	Cupin 2, conserved barrel domain protein
FOL01_RS04390	COG4977	sequence-specific DNA binding
FOL01_RS04395	COG2211	Major facilitator Superfamily
FOL01_RS04395	COG2190	(PTS) system
FOL01_RS04400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOL01_RS04405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOL01_RS04415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_RS04425	COG4708	membrane
FOL01_RS04430	COG0481	GTPase activity
FOL01_RS04435	COG2814	Major facilitator Superfamily
FOL01_RS04470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_RS04475	COG0277	FAD linked oxidase domain protein
FOL01_RS04485	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOL01_RS04490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_RS04500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOL01_RS04500	COG2755	lipolytic protein G-D-S-L family
FOL01_RS04510	COG0071	Belongs to the small heat shock protein (HSP20) family
FOL01_RS04560	COG0588	phosphoglycerate mutase activity
FOL01_RS04580	COG3022	response to hydroperoxide
FOL01_RS04585	COG1609	Transcriptional regulator
FOL01_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_RS04625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOL01_RS04630	COG1396	sequence-specific DNA binding
FOL01_RS04650	COG1476	TRANSCRIPTIONal
FOL01_RS04660	COG3973	AAA domain
FOL01_RS04740	COG4464	protein tyrosine phosphatase activity
FOL01_RS04750	COG0489	protein tyrosine kinase activity
FOL01_RS04755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOL01_RS04760	COG1215	transferase activity, transferring glycosyl groups
FOL01_RS04785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOL01_RS04795	COG1088	dTDP-glucose 4,6-dehydratase activity
FOL01_RS04800	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOL01_RS04820	COG2801	Transposase and inactivated derivatives
FOL01_RS04875	COG0542	response to heat
FOL01_RS04900	COG1192	Involved in chromosome partitioning
FOL01_RS04925	COG0741	lytic transglycosylase activity
FOL01_RS04925	COG1196	nuclear chromosome segregation
FOL01_RS04925	COG0739	heme binding
FOL01_RS04965	COG1609	Transcriptional regulator
FOL01_RS04975	COG0366	Alpha amylase catalytic
FOL01_RS04985	COG2223	nitrite transmembrane transporter activity
FOL01_RS05000	COG0351	phosphomethylpyrimidine kinase
FOL01_RS05005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_RS05015	COG1397	ADP-ribosylglycohydrolase
FOL01_RS05025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOL01_RS05035	COG1131	(ABC) transporter
FOL01_RS05040	COG0537	adenosine 5'-monophosphoramidase activity
FOL01_RS05050	COG3104	oligopeptide transport
FOL01_RS05055	COG0556	nucleotide-excision repair
FOL01_RS05070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOL01_RS05080	COG0116	Belongs to the methyltransferase superfamily
FOL01_RS05090	COG3599	regulation of cell shape
FOL01_RS05095	COG4474	Belongs to the UPF0398 family
FOL01_RS05100	COG3331	DNA recombination
FOL01_RS05105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOL01_RS05110	COG3935	DnaD domain protein
FOL01_RS05125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOL01_RS05125	COG1199	ATP-dependent helicase activity
FOL01_RS05130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOL01_RS05145	COG1304	FMN binding
FOL01_RS05155	COG0706	membrane insertase activity
FOL01_RS05165	COG5002	protein histidine kinase activity
FOL01_RS05170	COG0745	RESPONSE REGULATOR receiver
FOL01_RS05185	COG1484	DNA-dependent DNA replication
FOL01_RS05195	COG0237	dephospho-CoA kinase activity
FOL01_RS05200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOL01_RS05205	COG3759	membrane
FOL01_RS05210	COG0604	alcohol dehydrogenase
FOL01_RS05215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_RS05220	COG1846	Transcriptional regulator
FOL01_RS05230	COG0577	efflux transmembrane transporter activity
FOL01_RS05300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOL01_RS05300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOL01_RS05305	COG0670	Belongs to the BI1 family
FOL01_RS05310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOL01_RS05320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_RS05325	COG1363	Peptidase, m42
FOL01_RS05330	COG0572	uridine kinase
FOL01_RS05335	COG5002	protein histidine kinase activity
FOL01_RS05340	COG0745	RESPONSE REGULATOR receiver
FOL01_RS05355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOL01_RS05360	COG0358	DNA primase activity
FOL01_RS05455	COG2963	transposase activity
FOL01_RS05460	COG2801	Transposase and inactivated derivatives
FOL01_RS05480	COG0542	response to heat
FOL01_RS05535	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOL01_RS05540	COG2826	transposase and inactivated derivatives, IS30 family
FOL01_RS05560	COG2115	Belongs to the xylose isomerase family
FOL01_RS05570	COG2017	converts alpha-aldose to the beta-anomer
FOL01_RS05575	COG3507	Belongs to the glycosyl hydrolase 43 family
FOL01_RS05580	COG2211	Major facilitator Superfamily
FOL01_RS05585	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_RS05630	COG1125	glycine betaine transport
FOL01_RS05665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOL01_RS05710	COG2801	Transposase and inactivated derivatives
FOL01_RS05770	COG2814	Major facilitator Superfamily
FOL01_RS05785	COG2261	transglycosylase associated protein
FOL01_RS05800	COG2217	Heavy metal translocating P-type atpase
FOL01_RS05805	COG2217	Heavy metal translocating P-type atpase
FOL01_RS05825	COG1388	LysM domain
FOL01_RS05840	COG3328	transposase activity
FOL01_RS05845	COG2963	transposase activity
FOL01_RS05855	COG2124	cytochrome p450
FOL01_RS05860	COG2963	transposase activity
FOL01_RS05865	COG2801	Transposase and inactivated derivatives
FOL01_RS05925	COG3620	sequence-specific DNA binding
FOL01_RS05930	COG0300	oxidoreductase activity
FOL01_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS06000	COG0531	amino acid
FOL01_RS06010	COG1554	hydrolase, family 65, central catalytic
FOL01_RS06020	COG2188	Transcriptional regulator
FOL01_RS06035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOL01_RS06035	COG1263	PTS System
FOL01_RS06035	COG2190	(PTS) system
FOL01_RS06040	COG0024	Methionine aminopeptidase
FOL01_RS06050	COG4166	transmembrane transport
FOL01_RS06065	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOL01_RS06080	COG0095	Lipoate-protein ligase
FOL01_RS06085	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOL01_RS06090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOL01_RS06095	COG0742	ribosomal rna small subunit methyltransferase
FOL01_RS06100	COG4471	UPF0298 protein
FOL01_RS06105	COG0772	Belongs to the SEDS family
FOL01_RS06110	COG1217	gtp-binding protein TYPA
FOL01_RS06115	COG0483	inositol monophosphate 1-phosphatase activity
FOL01_RS06120	COG4476	Belongs to the UPF0223 family
FOL01_RS06125	COG0242	peptide deformylase activity
FOL01_RS06135	COG5503	Protein of unknown function (DUF1447)
FOL01_RS06145	COG1597	lipid kinase activity
FOL01_RS06155	COG1464	Belongs to the NlpA lipoprotein family
FOL01_RS06160	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOL01_RS06175	COG4175	Glycine betaine
FOL01_RS06175	COG3448	diguanylate cyclase activity
FOL01_RS06185	COG1227	inorganic diphosphatase activity
FOL01_RS06195	COG0187	DNA topoisomerase II activity
FOL01_RS06200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOL01_RS06210	COG4974	Belongs to the 'phage' integrase family
FOL01_RS06215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOL01_RS06220	COG0758	DNA mediated transformation
FOL01_RS06225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOL01_RS06235	COG4479	Belongs to the UPF0346 family
FOL01_RS06245	COG2755	lipolytic protein G-D-S-L family
FOL01_RS06250	COG1307	EDD domain protein, DegV family
FOL01_RS06255	COG1307	EDD domain protein, DegV family
FOL01_RS06265	COG3142	Participates in the control of copper homeostasis
FOL01_RS06270	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FOL01_RS06275	COG0196	riboflavin kinase activity
FOL01_RS06280	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOL01_RS06285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOL01_RS06290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOL01_RS06300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOL01_RS06305	COG0195	Participates in both transcription termination and antitermination
FOL01_RS06310	COG0779	Required for maturation of 30S ribosomal subunits
FOL01_RS06315	COG2239	Acts as a magnesium transporter
FOL01_RS06320	COG0564	pseudouridine synthase activity
FOL01_RS06325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOL01_RS06330	COG2357	RelA SpoT domain protein
FOL01_RS06350	COG0546	phosphoglycolate phosphatase activity
FOL01_RS06400	COG3118	belongs to the thioredoxin family
FOL01_RS06430	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOL01_RS06450	COG0268	Binds directly to 16S ribosomal RNA
FOL01_RS06455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOL01_RS06460	COG1466	dna polymerase III delta subunit
FOL01_RS06465	COG2333	competence protein COMEC
FOL01_RS06465	COG0658	competence protein
FOL01_RS06475	COG3906	Belongs to the UPF0473 family
FOL01_RS06490	COG4472	Bacterial protein of unknown function (DUF965)
FOL01_RS06495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOL01_RS06500	COG0513	Belongs to the DEAD box helicase family
FOL01_RS06505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOL01_RS06510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOL01_RS06520	COG0343	queuine tRNA-ribosyltransferase activity
FOL01_RS06550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOL01_RS06555	COG2255	four-way junction helicase activity
FOL01_RS06560	COG0632	four-way junction helicase activity
FOL01_RS06575	COG1739	Uncharacterized protein family UPF0029
FOL01_RS06580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOL01_RS06585	COG0322	excinuclease ABC activity
FOL01_RS06590	COG1668	transmembrane transport
FOL01_RS06595	COG4152	abc transporter atp-binding protein
FOL01_RS06600	COG1674	ftsk spoiiie
FOL01_RS06610	COG0628	permease
FOL01_RS06615	COG2706	6-phosphogluconolactonase activity
FOL01_RS06625	COG0751	glycine-tRNA ligase activity
FOL01_RS06630	COG0752	glycyl-tRNA synthetase alpha subunit
FOL01_RS06635	COG1381	Involved in DNA repair and RecF pathway recombination
FOL01_RS06640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOL01_RS06645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOL01_RS06650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOL01_RS06655	COG1702	phosphate starvation-inducible protein PhoH
FOL01_RS06660	COG1610	YqeY-like protein
FOL01_RS06665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOL01_RS06670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOL01_RS06675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOL01_RS06680	COG0124	histidyl-tRNA synthetase
FOL01_RS06685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOL01_RS06695	COG3425	synthase
FOL01_RS06700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOL01_RS06740	COG1227	inorganic diphosphatase activity
FOL01_RS06755	COG0531	amino acid
FOL01_RS06760	COG1609	Transcriptional regulator
FOL01_RS06765	COG0006	proline dipeptidase activity
FOL01_RS06780	COG1164	Oligoendopeptidase f
FOL01_RS06790	COG4862	establishment of competence for transformation
FOL01_RS06795	COG1393	Belongs to the ArsC family
FOL01_RS06800	COG3853	Toxic anion resistance protein (TelA)
FOL01_RS06810	COG3223	Belongs to the PsiE family
FOL01_RS06920	COG3728	DNA packaging
FOL01_RS06920	COG5484	DNA packaging
FOL01_RS06925	COG2261	transglycosylase associated protein
FOL01_RS06985	COG0629	single-stranded DNA binding
FOL01_RS07035	COG1396	sequence-specific DNA binding
FOL01_RS07050	COG0582	viral genome integration into host DNA
FOL01_RS07075	COG0561	phosphatase activity
FOL01_RS07080	COG1970	mechanosensitive ion channel activity
FOL01_RS07085	COG1428	Deoxynucleoside kinase
FOL01_RS07090	COG0791	NLP P60 protein
FOL01_RS07100	COG1942	4-Oxalocrotonate Tautomerase
FOL01_RS07105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOL01_RS07115	COG0335	large ribosomal subunit rRNA binding
FOL01_RS07120	COG0336	Belongs to the RNA methyltransferase TrmD family
FOL01_RS07125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOL01_RS07130	COG0588	phosphoglycerate mutase activity
FOL01_RS07135	COG0228	four-way junction DNA binding
FOL01_RS07140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOL01_RS07145	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOL01_RS07150	COG0552	protein localization to endoplasmic reticulum
FOL01_RS07155	COG1196	nuclear chromosome segregation
FOL01_RS07160	COG0571	ribonuclease III activity
FOL01_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOL01_RS07170	COG0416	fatty acid biosynthetic process
FOL01_RS07175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOL01_RS07180	COG1461	Dihydroxyacetone kinase
FOL01_RS07190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOL01_RS07200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOL01_RS07205	COG1162	GTPase activity
FOL01_RS07210	COG2815	serine threonine protein kinase
FOL01_RS07210	COG0515	serine threonine protein kinase
FOL01_RS07215	COG0631	protein serine/threonine phosphatase activity
FOL01_RS07220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOL01_RS07220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOL01_RS07225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOL01_RS07230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOL01_RS07235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOL01_RS07270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOL01_RS07275	COG2252	PERMEase
FOL01_RS07280	COG0217	transcriptional regulatory protein
FOL01_RS07285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOL01_RS07295	COG0588	phosphoglycerate mutase activity
FOL01_RS07305	COG3599	regulation of cell shape
FOL01_RS07315	COG0762	integral membrane protein
FOL01_RS07320	COG1799	cell septum assembly
FOL01_RS07325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOL01_RS07330	COG0849	cell division
FOL01_RS07335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOL01_RS07340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOL01_RS07345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOL01_RS07350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOL01_RS07355	COG0768	penicillin binding
FOL01_RS07370	COG2001	Belongs to the MraZ family
FOL01_RS07385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOL01_RS07390	COG2264	protein methyltransferase activity
FOL01_RS07400	COG0833	amino acid
FOL01_RS07410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOL01_RS07415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_RS07420	COG1126	abc transporter atp-binding protein
FOL01_RS07425	COG0765	amino acid transport
FOL01_RS07445	COG1077	Cell shape determining protein MreB Mrl
FOL01_RS07450	COG2003	Belongs to the UPF0758 family
FOL01_RS07465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOL01_RS07470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOL01_RS07475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_RS07480	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOL01_RS07495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOL01_RS07500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOL01_RS07520	COG1388	LysM domain
FOL01_RS07530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOL01_RS07540	COG0494	nUDIX hydrolase
FOL01_RS07545	COG1278	Cold shock
FOL01_RS07565	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOL01_RS07570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOL01_RS07575	COG4988	ABC transporter
FOL01_RS07580	COG1294	oxidase, subunit
FOL01_RS07585	COG1271	oxidase subunit
FOL01_RS07700	COG1098	S1 RNA binding domain
FOL01_RS07710	COG0586	Pfam SNARE associated Golgi protein
FOL01_RS07720	COG0194	GDP metabolic process
FOL01_RS07725	COG0497	DNA recombination
FOL01_RS07730	COG1438	arginine binding
FOL01_RS07735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOL01_RS07740	COG0142	geranyltranstransferase activity
FOL01_RS07745	COG1722	exodeoxyribonuclease VII activity
FOL01_RS07750	COG1570	exodeoxyribonuclease VII activity
FOL01_RS07755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOL01_RS07760	COG4720	Psort location CytoplasmicMembrane, score
FOL01_RS07775	COG0363	glucosamine-6-phosphate deaminase activity
FOL01_RS07780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOL01_RS07790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOL01_RS07795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOL01_RS07805	COG1323	Belongs to the UPF0348 family
FOL01_RS07810	COG2226	methyltransferase
FOL01_RS07815	COG0799	negative regulation of ribosome biogenesis
FOL01_RS07820	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOL01_RS07825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOL01_RS07835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOL01_RS07840	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOL01_RS07845	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOL01_RS07855	COG0531	amino acid
FOL01_RS07860	COG0459	protein refolding
FOL01_RS07865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOL01_RS07870	COG0488	(ABC) transporter
FOL01_RS07880	COG0525	valine-tRNA ligase activity
FOL01_RS07890	COG1272	protein, Hemolysin III
FOL01_RS07905	COG0589	response to stress
FOL01_RS07915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOL01_RS07925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_RS07935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOL01_RS07940	COG3557	Belongs to the UPF0374 family
FOL01_RS07945	COG2137	regulation of response to DNA damage stimulus
FOL01_RS07955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOL01_RS07965	COG0581	inorganic phosphate transmembrane transporter activity
FOL01_RS07970	COG0573	inorganic phosphate transmembrane transporter activity
FOL01_RS07985	COG0647	UMP catabolic process
FOL01_RS07990	COG4470	Protein conserved in bacteria
FOL01_RS07995	COG0737	Belongs to the 5'-nucleotidase family
FOL01_RS08010	COG0006	proline dipeptidase activity
FOL01_RS08015	COG4948	Mandelate Racemase Muconate Lactonizing
FOL01_RS08025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOL01_RS08030	COG1169	isochorismate synthase
FOL01_RS08060	COG0577	efflux transmembrane transporter activity
FOL01_RS08060	COG1136	(ABC) transporter
FOL01_RS08070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_RS08105	COG1064	alcohol dehydrogenase
FOL01_RS08110	COG4974	Belongs to the 'phage' integrase family
FOL01_RS08155	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOL01_RS08165	COG4974	Belongs to the 'phage' integrase family
FOL01_RS08175	COG0732	type I restriction modification DNA specificity domain
FOL01_RS08180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOL01_RS08185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOL01_RS08190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOL01_RS08215	COG0174	glutamine synthetase
FOL01_RS08220	COG0789	Transcriptional regulator
FOL01_RS08225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOL01_RS08230	COG0584	glycerophosphoryl diester phosphodiesterase
FOL01_RS08245	COG1388	LysM domain
FOL01_RS08245	COG3942	CHAP domain
FOL01_RS08250	COG1940	carbohydrate kinase activity
FOL01_RS08265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOL01_RS08270	COG0768	penicillin binding
FOL01_RS08280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOL01_RS08285	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_RS08290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOL01_RS08295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_RS08295	COG0072	phenylalanine-tRNA ligase activity
FOL01_RS08300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOL01_RS08305	COG1733	regulation of RNA biosynthetic process
FOL01_RS08310	COG2814	Major facilitator Superfamily
FOL01_RS08320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_RS08330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOL01_RS08335	COG0653	protein targeting
FOL01_RS08345	COG4956	integral membrane protein (PIN domain superfamily)
FOL01_RS08355	COG0756	dUTP diphosphatase activity
FOL01_RS08365	COG0791	NLP P60 protein
FOL01_RS08370	COG3942	CHAP domain
FOL01_RS08370	COG1388	LysM domain
FOL01_RS08385	COG0542	response to heat
FOL01_RS08390	COG0604	alcohol dehydrogenase
FOL01_RS08400	COG0028	Belongs to the TPP enzyme family
FOL01_RS08440	COG0740	serine-type endopeptidase activity
FOL01_RS08445	COG1481	regulation of sporulation
FOL01_RS08450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOL01_RS08460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOL01_RS08485	COG1573	uracil-dna glycosylase
FOL01_RS08490	COG0366	Alpha amylase catalytic
FOL01_RS08505	COG3775	system Galactitol-specific IIC component
FOL01_RS08535	COG0159	tryptophan synthase activity
FOL01_RS08545	COG2115	Belongs to the xylose isomerase family
FOL01_RS08575	COG3534	alpha-L-arabinofuranosidase
FOL01_RS08580	COG2188	Transcriptional regulator
FOL01_RS08590	COG0667	Aldo Keto reductase
FOL01_RS08595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOL01_RS08625	COG0574	Belongs to the PEP-utilizing enzyme family
FOL01_RS08625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOL01_RS08630	COG2390	Transcriptional regulator
FOL01_RS08645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOL01_RS08650	COG0477	Major facilitator Superfamily
FOL01_RS08665	COG2233	PERMEase
FOL01_RS08670	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_RS08700	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_RS08705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOL01_RS08710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOL01_RS08715	COG0101	tRNA pseudouridine synthase activity
FOL01_RS08725	COG1122	ATPase activity
FOL01_RS08730	COG1122	ATPase activity
FOL01_RS08740	COG1252	NADH dehydrogenase
FOL01_RS08745	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOL01_RS08750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOL01_RS08755	COG1121	(ABC) transporter
FOL01_RS08765	COG0222	ribosome binding
FOL01_RS08770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOL01_RS08775	COG0081	regulation of translation
FOL01_RS08780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOL01_RS08795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOL01_RS08805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_RS08810	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOL01_RS08815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOL01_RS08820	COG0284	orotidine-5'-phosphate decarboxylase activity
FOL01_RS08825	COG0167	dihydroorotate dehydrogenase activity
FOL01_RS08830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOL01_RS08835	COG0505	Belongs to the CarA family
FOL01_RS08845	COG0540	Belongs to the ATCase OTCase family
FOL01_RS08850	COG0517	IMP dehydrogenase activity
FOL01_RS08850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOL01_RS08855	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOL01_RS08860	COG1854	S-ribosylhomocysteine lyase activity
FOL01_RS08865	COG0215	cysteine-tRNA ligase activity
FOL01_RS08870	COG0667	Aldo Keto reductase
FOL01_RS08880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOL01_RS08890	COG1464	Belongs to the NlpA lipoprotein family
FOL01_RS08895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_RS08910	COG0203	ribosomal protein L17
FOL01_RS08915	COG0202	RNA polymerase activity
FOL01_RS08920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOL01_RS08925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOL01_RS08930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOL01_RS08935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOL01_RS08950	COG0200	Binds to the 23S rRNA
FOL01_RS08955	COG1841	ribosomal large subunit assembly
FOL01_RS08960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOL01_RS08965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOL01_RS08970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOL01_RS08975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOL01_RS08980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOL01_RS08985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOL01_RS08990	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOL01_RS09000	COG0255	Belongs to the universal ribosomal protein uL29 family
FOL01_RS09005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOL01_RS09015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOL01_RS09020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOL01_RS09025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOL01_RS09030	COG0089	rRNA binding
FOL01_RS09040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOL01_RS09045	COG0051	transcription antitermination factor activity, RNA binding
FOL01_RS09050	COG2826	transposase and inactivated derivatives, IS30 family
FOL01_RS09055	COG0142	geranyltranstransferase activity
FOL01_RS09060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOL01_RS09075	COG1214	PFAM Peptidase M22, glycoprotease
FOL01_RS09085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOL01_RS09105	COG3870	Protein conserved in bacteria
FOL01_RS09110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOL01_RS09120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOL01_RS09125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOL01_RS09130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOL01_RS09145	COG2813	Specifically methylates the guanine in position
FOL01_RS09155	COG0488	(ABC) transporter
FOL01_RS09165	COG2814	Major facilitator Superfamily
FOL01_RS09190	COG0500	methyltransferase
FOL01_RS09195	COG1979	alcohol dehydrogenase
FOL01_RS09205	COG0085	RNA polymerase activity
FOL01_RS09210	COG0542	response to heat
FOL01_RS09215	COG4463	regulation of RNA biosynthetic process
FOL01_RS09240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOL01_RS09245	COG1428	Deoxynucleoside kinase
FOL01_RS09255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOL01_RS09260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOL01_RS09265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOL01_RS09270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOL01_RS09275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOL01_RS09280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOL01_RS09285	COG0356	it plays a direct role in the translocation of protons across the membrane
FOL01_RS09290	COG2233	PERMEase
FOL01_RS09295	COG0702	epimerase
FOL01_RS09300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOL01_RS09305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOL01_RS09310	COG0009	L-threonylcarbamoyladenylate synthase
FOL01_RS09315	COG2890	protein-(glutamine-N5) methyltransferase activity
FOL01_RS09325	COG1435	thymidine kinase activity
FOL01_RS09330	COG3442	glutamine amidotransferase
FOL01_RS09335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOL01_RS09340	COG1482	cell wall glycoprotein biosynthetic process
FOL01_RS09360	COG1132	(ABC) transporter
FOL01_RS09365	COG1132	(ABC) transporter
FOL01_RS09370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOL01_RS09375	COG0588	phosphoglycerate mutase activity
FOL01_RS09390	COG0708	Exodeoxyribonuclease III
FOL01_RS09395	COG1454	alcohol dehydrogenase
FOL01_RS09395	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_RS09400	COG2217	Heavy metal translocating P-type atpase
FOL01_RS09420	COG3590	peptidase
FOL01_RS09430	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOL01_RS09435	COG2188	Transcriptional regulator
FOL01_RS09440	COG2814	Major facilitator Superfamily
FOL01_RS09445	COG1418	mRNA catabolic process
FOL01_RS09460	COG0765	amino acid transport
FOL01_RS09465	COG1126	abc transporter atp-binding protein
FOL01_RS09470	COG0765	amino acid transport
FOL01_RS09490	COG0656	L-ascorbic acid biosynthetic process
FOL01_RS09495	COG2160	L-arabinose isomerase activity
FOL01_RS09515	COG0534	Mate efflux family protein
FOL01_RS09530	COG0488	(ABC) transporter
FOL01_RS09540	COG1121	(ABC) transporter
FOL01_RS09550	COG1846	Transcriptional regulator
FOL01_RS09555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOL01_RS09555	COG2755	lipolytic protein G-D-S-L family
FOL01_RS09560	COG3091	SprT-like family
FOL01_RS09585	COG3104	oligopeptide transport
FOL01_RS09630	COG0745	RESPONSE REGULATOR receiver
FOL01_RS09640	COG0012	GTP binding
FOL01_RS09650	COG1475	DNA binding
FOL01_RS09655	COG1192	Involved in chromosome partitioning
FOL01_RS09660	COG0357	Ribosomal RNA small subunit methyltransferase G
FOL01_RS09665	COG1194	a g-specific adenine glycosylase
FOL01_RS09675	COG5002	protein histidine kinase activity
FOL01_RS09680	COG0745	RESPONSE REGULATOR receiver
FOL01_RS09685	COG0531	amino acid
FOL01_RS09695	COG0318	PFAM AMP-dependent synthetase and ligase
FOL01_RS09700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOL01_RS09710	COG4443	Transcriptional Coactivator p15 (PC4)
FOL01_RS09715	COG0252	asparaginase activity
FOL01_RS09720	COG0531	amino acid
FOL01_RS09725	COG1113	amino acid transport
FOL01_RS09730	COG0719	Fe-S assembly protein
FOL01_RS09740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOL01_RS09745	COG0719	Fe-S assembly protein
FOL01_RS09750	COG0396	ATPase activity
FOL01_RS09755	COG0602	queuosine metabolic process
FOL01_RS09760	COG1328	CTP reductase activity
FOL01_RS09770	COG0657	acetylesterase activity
FOL01_RS09780	COG0531	amino acid
FOL01_RS09795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOL01_RS09800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOL01_RS09810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOL01_RS09820	COG0477	Major facilitator Superfamily
FOL01_RS09825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOL01_RS09835	COG0531	amino acid
FOL01_RS09855	COG2855	membrane
FOL01_RS09865	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_RS09900	COG1113	amino acid transport
FOL01_RS09915	COG0628	permease
FOL01_RS09925	COG1254	Belongs to the acylphosphatase family
FOL01_RS09930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_RS09935	COG0765	amino acid transport
FOL01_RS09940	COG1126	abc transporter atp-binding protein
FOL01_RS09950	COG0656	L-ascorbic acid biosynthetic process
FOL01_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS09990	COG0436	Aminotransferase
FOL01_RS09995	COG0277	FAD linked oxidase domain protein
FOL01_RS10000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_RS10005	COG2357	RelA SpoT domain protein
FOL01_RS10010	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_RS10040	COG2211	Major facilitator Superfamily
FOL01_RS10045	COG3940	Belongs to the glycosyl hydrolase 43 family
FOL01_RS10050	COG0640	Transcriptional regulator
FOL01_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_RS10065	COG0477	Major facilitator Superfamily
FOL01_RS10070	COG1827	regulation of RNA biosynthetic process
FOL01_RS10085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOL01_RS10095	COG2233	PERMEase
FOL01_RS10100	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_RS10105	COG1268	BioY protein
FOL01_RS10110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOL01_RS10110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOL01_RS10130	COG2153	protein acetylation
FOL01_RS10140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_RS10145	COG0656	L-ascorbic acid biosynthetic process
FOL01_RS10155	COG1131	(ABC) transporter
FOL01_RS10160	COG2843	Capsule synthesis protein
FOL01_RS10165	COG1464	Belongs to the NlpA lipoprotein family
FOL01_RS10175	COG1609	Transcriptional regulator
FOL01_RS10180	COG1881	PFAM PEBP family protein
FOL01_RS10185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_RS10190	COG0436	Aminotransferase
FOL01_RS10195	COG0110	maltose O-acetyltransferase activity
FOL01_RS10200	COG0110	maltose O-acetyltransferase activity
FOL01_RS10205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOL01_RS10210	COG0531	amino acid
FOL01_RS10230	COG0149	triose-phosphate isomerase activity
FOL01_RS10230	COG0126	phosphoglycerate kinase activity
FOL01_RS10235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_RS10250	COG2017	converts alpha-aldose to the beta-anomer
FOL01_RS10255	COG0436	Aminotransferase
FOL01_RS10260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_RS10270	COG2252	PERMEase
FOL01_RS10275	COG2873	o-acetylhomoserine
FOL01_RS10295	COG1131	(ABC) transporter
FOL01_RS10305	COG0328	RNA-DNA hybrid ribonuclease activity
FOL01_RS10310	COG0561	phosphatase activity
FOL01_RS10315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOL01_RS10320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOL01_RS10325	COG1304	FMN binding
FOL01_RS10335	COG0384	phenazine biosynthesis protein PhzF
FOL01_RS10345	COG0460	homoserine dehydrogenase
FOL01_RS10350	COG0626	cystathionine gamma-synthase activity
FOL01_RS10355	COG0626	cystathionine gamma-synthase activity
FOL01_RS10360	COG0765	amino acid transport
FOL01_RS10365	COG1126	abc transporter atp-binding protein
FOL01_RS10390	COG1846	Transcriptional regulator
FOL01_RS10430	COG1301	dicarboxylic acid transport
FOL01_RS10435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_RS10470	COG1113	amino acid transport
FOL01_RS10475	COG0569	domain protein
FOL01_RS10480	COG5386	Cell surface protein
FOL01_RS10500	COG1120	ATPase activity
FOL01_RS10510	COG0765	amino acid transport
FOL01_RS10515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_RS10530	COG0706	membrane insertase activity
FOL01_RS10535	COG0594	ribonuclease P activity
FOL01_RS10540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOL01_RS10630	COG2409	Drug exporters of the RND superfamily
FOL01_RS10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_RS10745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation