locus-tag	class	description
FY536_RS00110	COG2918	glutathione biosynthetic process
FY536_RS00110	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY536_RS00140	COG1073	alpha beta
FY536_RS00150	COG0653	protein targeting
FY536_RS00155	COG0028	Belongs to the TPP enzyme family
FY536_RS00160	COG1695	Transcriptional regulator
FY536_RS00165	COG3479	Phenolic acid decarboxylase
FY536_RS00170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY536_RS00210	COG0653	protein targeting
FY536_RS00225	COG0438	transferase activity, transferring glycosyl groups
FY536_RS00230	COG2233	PERMEase
FY536_RS00235	COG2217	Heavy metal translocating P-type atpase
FY536_RS00250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY536_RS00255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY536_RS00260	COG1288	antiporter activity
FY536_RS00265	COG0477	Major facilitator Superfamily
FY536_RS00270	COG0481	GTPase activity
FY536_RS00280	COG1309	transcriptional regulator
FY536_RS00305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY536_RS00310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY536_RS00320	COG2195	Cleaves the N-terminal amino acid of tripeptides
FY536_RS00325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FY536_RS00330	COG2384	SAM-dependent methyltransferase
FY536_RS00355	COG2807	transmembrane transport
FY536_RS00360	COG4720	Psort location CytoplasmicMembrane, score
FY536_RS00365	COG0351	phosphomethylpyrimidine kinase
FY536_RS00370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY536_RS00370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY536_RS00375	COG1668	transmembrane transport
FY536_RS00380	COG4152	abc transporter atp-binding protein
FY536_RS00390	COG0604	alcohol dehydrogenase
FY536_RS00395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY536_RS00400	COG0516	GMP reductase activity
FY536_RS00405	COG0706	membrane insertase activity
FY536_RS00415	COG0765	amino acid transport
FY536_RS00420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY536_RS00430	COG3480	Lon protease (S16) C-terminal proteolytic domain
FY536_RS00435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY536_RS00440	COG0742	ribosomal rna small subunit methyltransferase
FY536_RS00445	COG4471	UPF0298 protein
FY536_RS00450	COG0772	Belongs to the SEDS family
FY536_RS00455	COG1217	gtp-binding protein TYPA
FY536_RS00460	COG0483	inositol monophosphate 1-phosphatase activity
FY536_RS00470	COG0242	peptide deformylase activity
FY536_RS00480	COG1876	peptidase activity
FY536_RS00495	COG1597	lipid kinase activity
FY536_RS00500	COG1227	inorganic diphosphatase activity
FY536_RS00510	COG0187	DNA topoisomerase II activity
FY536_RS00515	COG1739	Uncharacterized protein family UPF0029
FY536_RS00525	COG0322	excinuclease ABC activity
FY536_RS00530	COG0406	alpha-ribazole phosphatase activity
FY536_RS00540	COG0336	Belongs to the RNA methyltransferase TrmD family
FY536_RS00560	COG0477	Major facilitator Superfamily
FY536_RS00565	COG0228	four-way junction DNA binding
FY536_RS00570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY536_RS00575	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FY536_RS00580	COG0552	protein localization to endoplasmic reticulum
FY536_RS00585	COG0571	ribonuclease III activity
FY536_RS00590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY536_RS00595	COG0416	fatty acid biosynthetic process
FY536_RS00600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY536_RS00605	COG2252	PERMEase
FY536_RS00610	COG0018	arginyl-trna synthetase
FY536_RS00630	COG0501	Belongs to the peptidase M48B family
FY536_RS00635	COG1704	LemA family
FY536_RS00640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY536_RS00645	COG1461	Dihydroxyacetone kinase
FY536_RS00655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY536_RS00660	COG1564	THIamine pyrophosphokinase
FY536_RS00665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY536_RS00670	COG1162	GTPase activity
FY536_RS00675	COG0515	serine threonine protein kinase
FY536_RS00675	COG2815	serine threonine protein kinase
FY536_RS00680	COG0631	protein serine/threonine phosphatase activity
FY536_RS00685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY536_RS00685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY536_RS00690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY536_RS00695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FY536_RS00700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FY536_RS00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY536_RS00745	COG1942	4-Oxalocrotonate Tautomerase
FY536_RS00750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY536_RS00755	COG0513	Belongs to the DEAD box helicase family
FY536_RS00760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY536_RS00765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY536_RS00770	COG1862	Preprotein translocase
FY536_RS00775	COG0343	queuine tRNA-ribosyltransferase activity
FY536_RS00780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY536_RS00785	COG2255	four-way junction helicase activity
FY536_RS00790	COG0632	four-way junction helicase activity
FY536_RS00795	COG1757	Na H antiporter
FY536_RS00800	COG0758	DNA mediated transformation
FY536_RS00805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY536_RS00815	COG4479	Belongs to the UPF0346 family
FY536_RS00830	COG1307	EDD domain protein, DegV family
FY536_RS00835	COG1307	EDD domain protein, DegV family
FY536_RS00845	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY536_RS00850	COG5002	protein histidine kinase activity
FY536_RS00855	COG0745	RESPONSE REGULATOR receiver
FY536_RS00870	COG1484	DNA-dependent DNA replication
FY536_RS00885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY536_RS00895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY536_RS00900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY536_RS00905	COG0537	adenosine 5'-monophosphoramidase activity
FY536_RS00915	COG3759	membrane
FY536_RS00920	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY536_RS00935	COG4221	oxidoreductase activity
FY536_RS00940	COG0583	DNA-binding transcription factor activity
FY536_RS00945	COG2261	transglycosylase associated protein
FY536_RS00975	COG3237	CsbD-like
FY536_RS00990	COG2261	transglycosylase associated protein
FY536_RS01000	COG1461	Dihydroxyacetone kinase
FY536_RS01005	COG1942	4-Oxalocrotonate Tautomerase
FY536_RS01015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY536_RS01020	COG2226	methyltransferase
FY536_RS01125	COG0582	viral genome integration into host DNA
FY536_RS01135	COG1609	Transcriptional regulator
FY536_RS01140	COG0006	proline dipeptidase activity
FY536_RS01145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY536_RS01150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY536_RS01165	COG1846	Transcriptional regulator
FY536_RS01170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY536_RS01175	COG3599	regulation of cell shape
FY536_RS01190	COG1799	cell septum assembly
FY536_RS01205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY536_RS01210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY536_RS01215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY536_RS01220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY536_RS01225	COG0768	penicillin binding
FY536_RS01235	COG0275	rRNA processing
FY536_RS01240	COG2001	Belongs to the MraZ family
FY536_RS01250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FY536_RS01255	COG2264	protein methyltransferase activity
FY536_RS01260	COG0833	amino acid
FY536_RS01280	COG1077	Cell shape determining protein MreB Mrl
FY536_RS01285	COG2003	Belongs to the UPF0758 family
FY536_RS01320	COG0561	phosphatase activity
FY536_RS01325	COG0363	glucosamine-6-phosphate deaminase activity
FY536_RS01330	COG2207	Transcriptional regulator
FY536_RS01340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FY536_RS01385	COG0335	large ribosomal subunit rRNA binding
FY536_RS01395	COG3481	metal-dependent phosphohydrolase, HD sub domain
FY536_RS01400	COG4717	serine-type aminopeptidase activity
FY536_RS01405	COG0420	3'-5' exonuclease activity
FY536_RS01410	COG3679	Belongs to the UPF0342 family
FY536_RS01415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY536_RS01420	COG1438	arginine binding
FY536_RS01430	COG1136	(ABC) transporter
FY536_RS01435	COG0268	Binds directly to 16S ribosomal RNA
FY536_RS01440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY536_RS01445	COG1466	dna polymerase III delta subunit
FY536_RS01450	COG2333	competence protein COMEC
FY536_RS01450	COG0658	competence protein
FY536_RS01455	COG1555	photosystem II stabilization
FY536_RS01455	COG1596	polysaccharide export
FY536_RS01475	COG3906	Belongs to the UPF0473 family
FY536_RS01480	COG3906	Belongs to the UPF0473 family
FY536_RS01490	COG4472	Bacterial protein of unknown function (DUF965)
FY536_RS01495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY536_RS01500	COG2814	Major facilitator Superfamily
FY536_RS01505	COG2239	Acts as a magnesium transporter
FY536_RS01510	COG0564	pseudouridine synthase activity
FY536_RS01515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY536_RS01520	COG2357	RelA SpoT domain protein
FY536_RS01525	COG0562	UDP-galactopyranose mutase
FY536_RS01540	COG1758	RNA polymerase activity
FY536_RS01545	COG0194	GDP metabolic process
FY536_RS01550	COG0497	DNA recombination
FY536_RS01555	COG1438	arginine binding
FY536_RS01560	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY536_RS01565	COG0142	geranyltranstransferase activity
FY536_RS01570	COG1722	exodeoxyribonuclease VII activity
FY536_RS01580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY536_RS01585	COG0513	Belongs to the DEAD box helicase family
FY536_RS01590	COG0673	inositol 2-dehydrogenase activity
FY536_RS01595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY536_RS01605	COG0525	valine-tRNA ligase activity
FY536_RS01625	COG4175	Glycine betaine
FY536_RS01625	COG3448	diguanylate cyclase activity
FY536_RS01630	COG0589	response to stress
FY536_RS01650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY536_RS01655	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY536_RS01665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY536_RS01670	COG2084	Dehydrogenase
FY536_RS01675	COG0656	L-ascorbic acid biosynthetic process
FY536_RS01685	COG2160	L-arabinose isomerase activity
FY536_RS01700	COG2211	Major facilitator Superfamily
FY536_RS01705	COG3940	Belongs to the glycosyl hydrolase 43 family
FY536_RS01710	COG1609	Transcriptional regulator
FY536_RS01715	COG3706	GGDEF domain
FY536_RS01745	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY536_RS01750	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY536_RS01760	COG4720	Psort location CytoplasmicMembrane, score
FY536_RS01770	COG2814	Major facilitator Superfamily
FY536_RS01780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY536_RS01790	COG1230	cation diffusion facilitator family transporter
FY536_RS01795	COG0741	lytic transglycosylase activity
FY536_RS01800	COG1072	(Pantothenic acid kinase))
FY536_RS01805	COG3973	AAA domain
FY536_RS01815	COG3716	PTS system mannose fructose sorbose family IID component
FY536_RS01820	COG3715	PTS system
FY536_RS01880	COG3064	Membrane
FY536_RS01880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FY536_RS01880	COG3583	domain protein
FY536_RS01930	COG1368	sulfuric ester hydrolase activity
FY536_RS01945	COG0438	transferase activity, transferring glycosyl groups
FY536_RS01950	COG0438	transferase activity, transferring glycosyl groups
FY536_RS01960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY536_RS01965	COG4856	YbbR-like protein
FY536_RS01980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY536_RS01995	COG0802	atpase or kinase
FY536_RS02000	COG0280	phosphate acetyltransferase
FY536_RS02005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY536_RS02015	COG1983	PspC domain protein
FY536_RS02030	COG0735	belongs to the Fur family
FY536_RS02040	COG2070	2-Nitropropane dioxygenase
FY536_RS02050	COG1929	Belongs to the glycerate kinase type-1 family
FY536_RS02055	COG0024	Methionine aminopeptidase
FY536_RS02085	COG0464	growth
FY536_RS02105	COG0789	Transcriptional regulator
FY536_RS02110	COG0656	L-ascorbic acid biosynthetic process
FY536_RS02135	COG0577	efflux transmembrane transporter activity
FY536_RS02160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY536_RS02165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY536_RS02170	COG0305	Participates in initiation and elongation during chromosome replication
FY536_RS02175	COG0359	binds to the 23S rRNA
FY536_RS02185	COG0765	amino acid transport
FY536_RS02190	COG0765	amino acid transport
FY536_RS02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY536_RS02205	COG0194	GDP metabolic process
FY536_RS02215	COG0577	efflux transmembrane transporter activity
FY536_RS02215	COG1136	(ABC) transporter
FY536_RS02220	COG1132	(ABC) transporter
FY536_RS02225	COG1132	(ABC) transporter
FY536_RS02230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY536_RS02235	COG0588	phosphoglycerate mutase activity
FY536_RS02245	COG0708	Exodeoxyribonuclease III
FY536_RS02265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY536_RS02270	COG0772	Belongs to the SEDS family
FY536_RS02280	COG1077	Cell shape determining protein MreB Mrl
FY536_RS02285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY536_RS02290	COG0737	Belongs to the 5'-nucleotidase family
FY536_RS02300	COG0352	thiamine-phosphate diphosphorylase activity
FY536_RS02305	COG0351	phosphomethylpyrimidine kinase
FY536_RS02310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY536_RS02315	COG1511	domain protein
FY536_RS02325	COG3250	beta-galactosidase activity
FY536_RS02335	COG0588	phosphoglycerate mutase activity
FY536_RS02340	COG0492	ferredoxin-NADP+ reductase activity
FY536_RS02355	COG0596	Alpha beta hydrolase
FY536_RS02360	COG1733	regulation of RNA biosynthetic process
FY536_RS02370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY536_RS02380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FY536_RS02385	COG0653	protein targeting
FY536_RS02390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY536_RS02405	COG2337	Toxic component of a toxin-antitoxin (TA) module
FY536_RS02420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY536_RS02425	COG0504	CTP synthase activity
FY536_RS02435	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY536_RS02440	COG1088	dTDP-glucose 4,6-dehydratase activity
FY536_RS02450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY536_RS02455	COG1215	transferase activity, transferring glycosyl groups
FY536_RS02480	COG0438	transferase activity, transferring glycosyl groups
FY536_RS02485	COG0438	transferase activity, transferring glycosyl groups
FY536_RS02490	COG1078	dGTPase activity
FY536_RS02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY536_RS02505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY536_RS02520	COG5002	protein histidine kinase activity
FY536_RS02525	COG0745	RESPONSE REGULATOR receiver
FY536_RS02530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY536_RS02535	COG0629	single-stranded DNA binding
FY536_RS02540	COG0360	Binds together with S18 to 16S ribosomal RNA
FY536_RS02545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY536_RS02550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY536_RS02555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY536_RS02560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY536_RS02570	COG1074	ATP-dependent DNA helicase activity
FY536_RS02575	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FY536_RS02585	COG2813	Specifically methylates the guanine in position
FY536_RS02625	COG1064	alcohol dehydrogenase
FY536_RS02630	COG0203	ribosomal protein L17
FY536_RS02635	COG0202	RNA polymerase activity
FY536_RS02640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY536_RS02645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY536_RS02655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY536_RS02660	COG0563	adenylate kinase activity
FY536_RS02670	COG0200	Binds to the 23S rRNA
FY536_RS02675	COG1841	ribosomal large subunit assembly
FY536_RS02680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY536_RS02685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY536_RS02690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY536_RS02695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY536_RS02700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY536_RS02705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY536_RS02710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY536_RS02720	COG0255	Belongs to the universal ribosomal protein uL29 family
FY536_RS02725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY536_RS02730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY536_RS02735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY536_RS02740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY536_RS02745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY536_RS02750	COG0089	rRNA binding
FY536_RS02760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY536_RS02765	COG0051	transcription antitermination factor activity, RNA binding
FY536_RS02790	COG0438	transferase activity, transferring glycosyl groups
FY536_RS02800	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FY536_RS02805	COG2244	polysaccharide biosynthetic process
FY536_RS02825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY536_RS02840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FY536_RS02850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY536_RS02855	COG0456	acetyltransferase
FY536_RS02865	COG1214	PFAM Peptidase M22, glycoprotease
FY536_RS02895	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY536_RS02900	COG1428	Deoxynucleoside kinase
FY536_RS02905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY536_RS02910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY536_RS02915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY536_RS02920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY536_RS02930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY536_RS02935	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY536_RS02940	COG0356	it plays a direct role in the translocation of protons across the membrane
FY536_RS02945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY536_RS02950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY536_RS02955	COG0009	L-threonylcarbamoyladenylate synthase
FY536_RS02960	COG2890	protein-(glutamine-N5) methyltransferase activity
FY536_RS02970	COG1435	thymidine kinase activity
FY536_RS02975	COG3442	glutamine amidotransferase
FY536_RS02980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY536_RS02990	COG0531	amino acid
FY536_RS03005	COG0500	methyltransferase
FY536_RS03010	COG0531	amino acid
FY536_RS03015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY536_RS03030	COG2244	polysaccharide biosynthetic process
FY536_RS03045	COG0495	leucyl-tRNA aminoacylation
FY536_RS03050	COG0671	phosphoesterase, PA-phosphatase related
FY536_RS03060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY536_RS03065	COG1114	Component of the transport system for branched-chain amino acids
FY536_RS03080	COG0531	amino acid
FY536_RS03095	COG1957	nucleoside hydrolase
FY536_RS03100	COG1136	(ABC) transporter
FY536_RS03105	COG0577	efflux transmembrane transporter activity
FY536_RS03110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY536_RS03115	COG0784	Response regulator, receiver
FY536_RS03120	COG4251	negative regulation of phosphorylation
FY536_RS03125	COG1288	antiporter activity
FY536_RS03135	COG1869	D-ribose catabolic process
FY536_RS03145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FY536_RS03185	COG1522	sequence-specific DNA binding
FY536_RS03195	COG0222	ribosome binding
FY536_RS03200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY536_RS03205	COG0081	regulation of translation
FY536_RS03210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY536_RS03235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY536_RS03240	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FY536_RS03245	COG0215	cysteine-tRNA ligase activity
FY536_RS03250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY536_RS03255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY536_RS03270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY536_RS03285	COG1482	cell wall glycoprotein biosynthetic process
FY536_RS03300	COG1272	protein, Hemolysin III
FY536_RS03305	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FY536_RS03310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FY536_RS03315	COG2188	Transcriptional regulator
FY536_RS03320	COG2814	Major facilitator Superfamily
FY536_RS03345	COG0488	(ABC) transporter
FY536_RS03350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY536_RS03355	COG1121	(ABC) transporter
FY536_RS03370	COG2755	lipolytic protein G-D-S-L family
FY536_RS03370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY536_RS03380	COG3104	oligopeptide transport
FY536_RS03390	COG0300	oxidoreductase activity
FY536_RS03410	COG5002	protein histidine kinase activity
FY536_RS03425	COG0012	GTP binding
FY536_RS03430	COG4481	Protein conserved in bacteria
FY536_RS03435	COG1475	DNA binding
FY536_RS03440	COG1192	Involved in chromosome partitioning
FY536_RS03445	COG0357	Ribosomal RNA small subunit methyltransferase G
FY536_RS03450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY536_RS03460	COG0657	acetylesterase activity
FY536_RS03470	COG0628	permease
FY536_RS03475	COG1254	Belongs to the acylphosphatase family
FY536_RS03480	COG1881	PFAM PEBP family protein
FY536_RS03490	COG4221	oxidoreductase activity
FY536_RS03495	COG0789	Transcriptional regulator
FY536_RS03500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY536_RS03505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FY536_RS03525	COG1959	2 iron, 2 sulfur cluster binding
FY536_RS03530	COG0477	Major facilitator Superfamily
FY536_RS03540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY536_RS03555	COG0702	epimerase
FY536_RS03560	COG0667	Aldo Keto reductase
FY536_RS03565	COG0586	Pfam SNARE associated Golgi protein
FY536_RS03575	COG0328	RNA-DNA hybrid ribonuclease activity
FY536_RS03580	COG0561	phosphatase activity
FY536_RS03585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY536_RS03590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY536_RS03625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY536_RS03650	COG3104	oligopeptide transport
FY536_RS03670	COG0492	ferredoxin-NADP+ reductase activity
FY536_RS03675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY536_RS03680	COG3118	belongs to the thioredoxin family
FY536_RS03695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY536_RS03725	COG0656	L-ascorbic acid biosynthetic process
FY536_RS03735	COG0583	DNA-binding transcription factor activity
FY536_RS03755	COG0604	alcohol dehydrogenase
FY536_RS03760	COG1902	pentaerythritol trinitrate reductase activity
FY536_RS03770	COG0789	Transcriptional regulator
FY536_RS03775	COG0583	DNA-binding transcription factor activity
FY536_RS03785	COG1285	pathogenesis
FY536_RS03800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY536_RS03885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY536_RS03895	COG0583	DNA-binding transcription factor activity
FY536_RS03900	COG1442	glycosyl transferase family 8
FY536_RS03905	COG0569	domain protein
FY536_RS03910	COG1113	amino acid transport
FY536_RS03920	COG0706	membrane insertase activity
FY536_RS03925	COG0594	ribonuclease P activity
FY536_RS03930	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY536_RS03935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY536_RS03940	COG0592	DNA-directed DNA polymerase activity
FY536_RS03945	COG2501	S4 domain
FY536_RS03950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY536_RS03955	COG0187	DNA topoisomerase II activity
FY536_RS03965	COG1368	sulfuric ester hydrolase activity
FY536_RS04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY536_RS04005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY536_RS04010	COG0084	hydrolase, TatD family'
FY536_RS04015	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FY536_RS04025	COG1253	flavin adenine dinucleotide binding
FY536_RS04030	COG4466	Protein conserved in bacteria
FY536_RS04035	COG2131	deaminase
FY536_RS04040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY536_RS04045	COG1316	TRANSCRIPTIONal
FY536_RS04060	COG1968	undecaprenyl-diphosphatase activity
FY536_RS04070	COG2235	arginine
FY536_RS04080	COG0531	amino acid
FY536_RS04105	COG0463	Glycosyl transferase, family 2
FY536_RS04115	COG0463	Glycosyl transferase, family 2
FY536_RS04125	COG1705	Flagellar rod assembly protein muramidase FlgJ
FY536_RS04125	COG1388	LysM domain
FY536_RS04135	COG2309	aminopeptidase activity
FY536_RS04145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY536_RS04155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY536_RS04160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FY536_RS04165	COG0252	asparaginase activity
FY536_RS04170	COG4443	Transcriptional Coactivator p15 (PC4)
FY536_RS04175	COG0745	RESPONSE REGULATOR receiver
FY536_RS04180	COG5002	protein histidine kinase activity
FY536_RS04190	COG0025	NhaP-type Na H and K H
FY536_RS04195	COG3118	belongs to the thioredoxin family
FY536_RS04210	COG0193	aminoacyl-tRNA hydrolase activity
FY536_RS04215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY536_RS04220	COG2244	polysaccharide biosynthetic process
FY536_RS04225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FY536_RS04260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FY536_RS04265	COG1609	Transcriptional regulator
FY536_RS04275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FY536_RS04280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY536_RS04320	COG1113	amino acid transport
FY536_RS04325	COG1737	Transcriptional regulator
FY536_RS04330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY536_RS04360	COG4463	regulation of RNA biosynthetic process
FY536_RS04365	COG0542	response to heat
FY536_RS04370	COG0085	RNA polymerase activity
FY536_RS04375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY536_RS04380	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FY536_RS04395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY536_RS04405	COG0813	purine-nucleoside phosphorylase activity
FY536_RS04425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY536_RS04430	COG3590	peptidase
FY536_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
FY536_RS04435	COG1454	alcohol dehydrogenase
FY536_RS04440	COG1252	NADH dehydrogenase
FY536_RS04450	COG1122	ATPase activity
FY536_RS04455	COG1122	ATPase activity
FY536_RS04465	COG0101	tRNA pseudouridine synthase activity
FY536_RS04475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY536_RS04490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY536_RS04495	COG3870	Protein conserved in bacteria
FY536_RS04500	COG0470	DNA polymerase III
FY536_RS04515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY536_RS04530	COG0667	Aldo Keto reductase
FY536_RS04535	COG1620	l-lactate permease
FY536_RS04540	COG0438	transferase activity, transferring glycosyl groups
FY536_RS04605	COG1063	alcohol dehydrogenase
FY536_RS04615	COG1811	Na channel or pump
FY536_RS04620	COG0583	DNA-binding transcription factor activity
FY536_RS04640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY536_RS04645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY536_RS04650	COG1070	Carbohydrate kinase
FY536_RS04655	COG1802	Transcriptional regulator
FY536_RS04660	COG0246	Mannitol dehydrogenase
FY536_RS04665	COG1312	Catalyzes the dehydration of D-mannonate
FY536_RS04670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY536_RS04680	COG2211	Major facilitator Superfamily
FY536_RS04690	COG1904	glucuronate isomerase
FY536_RS04705	COG2207	Transcriptional regulator
FY536_RS04710	COG0534	Mate efflux family protein
FY536_RS04725	COG2115	Belongs to the xylose isomerase family
FY536_RS04750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY536_RS04760	COG0531	amino acid
FY536_RS04770	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY536_RS04775	COG1914	H( )-stimulated, divalent metal cation uptake system
FY536_RS04790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FY536_RS04795	COG1481	regulation of sporulation
FY536_RS04800	COG0740	serine-type endopeptidase activity
FY536_RS04815	COG0346	lactoylglutathione lyase activity
FY536_RS04845	COG0110	maltose O-acetyltransferase activity
FY536_RS04855	COG0542	response to heat
FY536_RS04865	COG0756	dUTP diphosphatase activity
FY536_RS04875	COG4956	integral membrane protein (PIN domain superfamily)
FY536_RS04885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY536_RS04890	COG0072	phenylalanine-tRNA ligase activity
FY536_RS04890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY536_RS04895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY536_RS04905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY536_RS04910	COG0768	penicillin binding
FY536_RS04915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FY536_RS04925	COG1940	carbohydrate kinase activity
FY536_RS04930	COG0791	NLP P60 protein
FY536_RS04950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY536_RS04955	COG0789	Transcriptional regulator
FY536_RS04960	COG0174	glutamine synthetase
FY536_RS04980	COG0697	spore germination
FY536_RS04985	COG4708	membrane
FY536_RS05015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY536_RS05020	COG2188	Transcriptional regulator
FY536_RS05025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY536_RS05035	COG2252	PERMEase
FY536_RS05040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY536_RS05045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FY536_RS05055	COG2246	polysaccharide biosynthetic process
FY536_RS05060	COG0561	phosphatase activity
FY536_RS05065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY536_RS05070	COG4589	Belongs to the CDS family
FY536_RS05075	COG0442	prolyl-tRNA aminoacylation
FY536_RS05085	COG2176	DNA-directed DNA polymerase activity
FY536_RS05110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FY536_RS05125	COG0006	proline dipeptidase activity
FY536_RS05140	COG4470	Protein conserved in bacteria
FY536_RS05145	COG0647	UMP catabolic process
FY536_RS05155	COG0573	inorganic phosphate transmembrane transporter activity
FY536_RS05160	COG0581	inorganic phosphate transmembrane transporter activity
FY536_RS05170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY536_RS05175	COG0704	Plays a role in the regulation of phosphate uptake
FY536_RS05185	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FY536_RS05200	COG0557	exoribonuclease II activity
FY536_RS05205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY536_RS05210	COG3104	oligopeptide transport
FY536_RS05215	COG2153	protein acetylation
FY536_RS05225	COG1278	Cold shock
FY536_RS05240	COG2183	response to ionizing radiation
FY536_RS05265	COG2217	Heavy metal translocating P-type atpase
FY536_RS05275	COG0768	penicillin binding
FY536_RS05290	COG1051	belongs to the nudix hydrolase family
FY536_RS05300	COG2076	Multidrug Resistance protein
FY536_RS05305	COG1846	Transcriptional regulator
FY536_RS05310	COG0456	acetyltransferase
FY536_RS05320	COG2233	PERMEase
FY536_RS05330	COG0628	permease
FY536_RS05335	COG0402	S-adenosylhomocysteine deaminase activity
FY536_RS05340	COG0745	RESPONSE REGULATOR receiver
FY536_RS05345	COG2017	converts alpha-aldose to the beta-anomer
FY536_RS05350	COG0166	Belongs to the GPI family
FY536_RS05360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY536_RS05365	COG1302	Protein conserved in bacteria
FY536_RS05375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY536_RS05380	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY536_RS05385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY536_RS05400	COG0049	tRNA binding
FY536_RS05405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY536_RS05410	COG3842	ATPase activity
FY536_RS05415	COG0573	inorganic phosphate transmembrane transporter activity
FY536_RS05420	COG1177	transmembrane transport
FY536_RS05425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FY536_RS05430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FY536_RS05440	COG2814	Major facilitator Superfamily
FY536_RS05450	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY536_RS05455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY536_RS05460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY536_RS05465	COG0492	ferredoxin-NADP+ reductase activity
FY536_RS05485	COG0149	triose-phosphate isomerase activity
FY536_RS05525	COG0126	phosphoglycerate kinase activity
FY536_RS05540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FY536_RS05550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY536_RS05555	COG1713	HD superfamily hydrolase involved in NAD metabolism
FY536_RS05560	COG0799	negative regulation of ribosome biogenesis
FY536_RS05565	COG2226	methyltransferase
FY536_RS05570	COG1323	Belongs to the UPF0348 family
FY536_RS05580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY536_RS05585	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FY536_RS05590	COG0488	(ABC) transporter
FY536_RS05595	COG2137	regulation of response to DNA damage stimulus
FY536_RS05670	COG0582	viral genome integration into host DNA
FY536_RS05675	COG3557	Belongs to the UPF0374 family
FY536_RS05685	COG0436	Aminotransferase
FY536_RS05690	COG4684	Psort location CytoplasmicMembrane, score
FY536_RS05695	COG1970	mechanosensitive ion channel activity
FY536_RS05700	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FY536_RS05705	COG1418	mRNA catabolic process
FY536_RS05710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY536_RS05715	COG0459	protein refolding
FY536_RS05725	COG4720	Psort location CytoplasmicMembrane, score
FY536_RS05730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY536_RS05735	COG4807	Protein conserved in bacteria
FY536_RS05740	COG0716	FMN binding
FY536_RS05745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY536_RS05755	COG1122	ATPase activity
FY536_RS05765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY536_RS05770	COG0667	Aldo Keto reductase
FY536_RS05775	COG0561	phosphatase activity
FY536_RS05785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY536_RS05795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY536_RS05800	COG1597	lipid kinase activity
FY536_RS05810	COG2706	6-phosphogluconolactonase activity
FY536_RS05815	COG0628	permease
FY536_RS05820	COG0586	Pfam SNARE associated Golgi protein
FY536_RS05825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FY536_RS05940	COG1705	Flagellar rod assembly protein muramidase FlgJ
FY536_RS05960	COG1278	Cold shock
FY536_RS05975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY536_RS05980	COG0779	Required for maturation of 30S ribosomal subunits
FY536_RS05985	COG0195	Participates in both transcription termination and antitermination
FY536_RS05990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FY536_RS06000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY536_RS06005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY536_RS06010	COG1674	ftsk spoiiie
FY536_RS06040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY536_RS06050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY536_RS06055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY536_RS06070	COG1193	negative regulation of DNA recombination
FY536_RS06075	COG0656	L-ascorbic acid biosynthetic process
FY536_RS06085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY536_RS06090	COG3425	synthase
FY536_RS06100	COG0860	N-Acetylmuramoyl-L-alanine amidase
FY536_RS06105	COG0124	histidyl-tRNA synthetase
FY536_RS06110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY536_RS06115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY536_RS06120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY536_RS06125	COG1610	YqeY-like protein
FY536_RS06130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY536_RS06135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY536_RS06140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY536_RS06145	COG1381	Involved in DNA repair and RecF pathway recombination
FY536_RS06155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY536_RS06160	COG0196	riboflavin kinase activity
FY536_RS06170	COG1388	LysM domain
FY536_RS06170	COG1134	teichoic acid transport
FY536_RS06175	COG1682	transport, permease protein
FY536_RS06190	COG2610	gluconate transmembrane transporter activity
FY536_RS06195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY536_RS06200	COG0612	Peptidase, M16
FY536_RS06205	COG0612	Peptidase, M16
FY536_RS06210	COG1426	Protein conserved in bacteria
FY536_RS06215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY536_RS06220	COG1546	Belongs to the CinA family
FY536_RS06220	COG1058	Belongs to the CinA family
FY536_RS06225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY536_RS06240	COG0024	Methionine aminopeptidase
FY536_RS06245	COG1719	4-vinyl reductase, 4VR
FY536_RS06255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY536_RS06260	COG1234	tRNA 3'-trailer cleavage
FY536_RS06265	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FY536_RS06265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY536_RS06275	COG4224	UPF0291 protein
FY536_RS06280	COG3763	UPF0154 protein
FY536_RS06285	COG0204	Acyl-transferase
FY536_RS06290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FY536_RS06295	COG2827	Endonuclease containing a URI domain
FY536_RS06300	COG0052	Belongs to the universal ribosomal protein uS2 family
FY536_RS06305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY536_RS06310	COG0528	UMP kinase activity
FY536_RS06320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY536_RS06325	COG1428	Deoxynucleoside kinase
FY536_RS06330	COG0546	phosphoglycolate phosphatase activity
FY536_RS06340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY536_RS06355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY536_RS06370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY536_RS06375	COG0617	tRNA 3'-terminal CCA addition
FY536_RS06380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY536_RS06400	COG4862	establishment of competence for transformation
FY536_RS06410	COG1164	Oligoendopeptidase f
FY536_RS06415	COG0752	glycyl-tRNA synthetase alpha subunit
FY536_RS06420	COG0751	glycine-tRNA ligase activity
FY536_RS06435	COG2814	Major facilitator Superfamily
FY536_RS06445	COG0765	amino acid transport
FY536_RS06450	COG1126	abc transporter atp-binding protein
FY536_RS06455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY536_RS06460	COG2814	Major facilitator Superfamily
FY536_RS06470	COG3331	DNA recombination
FY536_RS06475	COG4474	Belongs to the UPF0398 family
FY536_RS06490	COG0116	Belongs to the methyltransferase superfamily
FY536_RS06500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY536_RS06520	COG1132	(ABC) transporter
FY536_RS06525	COG0556	nucleotide-excision repair
FY536_RS06535	COG0564	pseudouridine synthase activity
FY536_RS06540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FY536_RS06545	COG0505	Belongs to the CarA family
FY536_RS06555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY536_RS06580	COG1304	FMN binding
FY536_RS06600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY536_RS06600	COG1199	ATP-dependent helicase activity
FY536_RS06610	COG0017	Asparaginyl-tRNA synthetase
FY536_RS06615	COG0488	(ABC) transporter
FY536_RS06630	COG0587	DNA-directed DNA polymerase activity
FY536_RS06635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FY536_RS06645	COG2996	Protein conserved in bacteria
FY536_RS06655	COG1187	pseudouridine synthase activity
FY536_RS06665	COG0514	ATP-dependent DNA helicase (RecQ)
FY536_RS06675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY536_RS06680	COG0539	negative regulation of cytoplasmic translation
FY536_RS06685	COG1160	GTP binding
FY536_RS06695	COG4975	Glucose uptake
FY536_RS06700	COG0561	phosphatase activity
FY536_RS06705	COG0095	Lipoate-protein ligase
FY536_RS06735	COG1316	TRANSCRIPTIONal
FY536_RS06745	COG0489	protein tyrosine kinase activity
FY536_RS06750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY536_RS06765	COG0583	DNA-binding transcription factor activity
FY536_RS06770	COG2855	membrane
FY536_RS06775	COG2199	diguanylate cyclase activity
FY536_RS06780	COG3883	PFAM NLP P60 protein
FY536_RS06780	COG0791	NLP P60 protein
FY536_RS06795	COG0358	DNA primase activity
FY536_RS06800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY536_RS06805	COG1420	regulation of RNA biosynthetic process
FY536_RS06810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY536_RS06815	COG0443	Heat shock 70 kDa protein
FY536_RS06820	COG0484	heat shock protein binding
FY536_RS06840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY536_RS06845	COG2211	Major facilitator Superfamily
FY536_RS06850	COG0745	RESPONSE REGULATOR receiver
FY536_RS06855	COG5002	protein histidine kinase activity
FY536_RS06860	COG0572	uridine kinase
FY536_RS06865	COG1363	Peptidase, m42
FY536_RS06870	COG0072	phenylalanine-tRNA ligase activity
FY536_RS06870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY536_RS06885	COG0670	Belongs to the BI1 family
FY536_RS06915	COG3706	GGDEF domain
FY536_RS06920	COG0583	DNA-binding transcription factor activity
FY536_RS06940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY536_RS06960	COG3479	Phenolic acid decarboxylase
FY536_RS06965	COG1695	Transcriptional regulator
FY536_RS06970	COG0028	Belongs to the TPP enzyme family
FY536_RS06975	COG0653	protein targeting
FY536_RS06985	COG1073	alpha beta
FY536_RS07015	COG2918	glutathione biosynthetic process
FY536_RS07015	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY536_RS07060	COG2217	Heavy metal translocating P-type atpase