locus-tag	class	description
WSWS_RS00010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WSWS_RS00015	COG1113	amino acid transport
WSWS_RS00030	COG1194	a g-specific adenine glycosylase
WSWS_RS00035	COG0357	Ribosomal RNA small subunit methyltransferase G
WSWS_RS00040	COG1192	Involved in chromosome partitioning
WSWS_RS00045	COG1475	DNA binding
WSWS_RS00050	COG4481	Protein conserved in bacteria
WSWS_RS00055	COG0012	GTP binding
WSWS_RS00065	COG0745	RESPONSE REGULATOR receiver
WSWS_RS00075	COG1686	Belongs to the peptidase S11 family
WSWS_RS00120	COG3104	oligopeptide transport
WSWS_RS00140	COG3091	SprT-like family
WSWS_RS00145	COG2755	lipolytic protein G-D-S-L family
WSWS_RS00145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WSWS_RS00150	COG0488	(ABC) transporter
WSWS_RS00155	COG0534	Mate efflux family protein
WSWS_RS00160	COG3153	acetyltransferase
WSWS_RS00175	COG1418	mRNA catabolic process
WSWS_RS00180	COG2814	Major facilitator Superfamily
WSWS_RS00185	COG2188	Transcriptional regulator
WSWS_RS00190	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
WSWS_RS00195	COG0351	phosphomethylpyrimidine kinase
WSWS_RS00210	COG0708	Exodeoxyribonuclease III
WSWS_RS00215	COG1121	(ABC) transporter
WSWS_RS00220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WSWS_RS00230	COG0531	amino acid
WSWS_RS00240	COG1181	Belongs to the D-alanine--D-alanine ligase family
WSWS_RS00245	COG1435	thymidine kinase activity
WSWS_RS00255	COG2890	protein-(glutamine-N5) methyltransferase activity
WSWS_RS00260	COG0009	L-threonylcarbamoyladenylate synthase
WSWS_RS00265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WSWS_RS00270	COG1511	domain protein
WSWS_RS00275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WSWS_RS00280	COG2233	PERMEase
WSWS_RS00285	COG0356	it plays a direct role in the translocation of protons across the membrane
WSWS_RS00290	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WSWS_RS00295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WSWS_RS00305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WSWS_RS00310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WSWS_RS00315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WSWS_RS00320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WSWS_RS00325	COG1428	Deoxynucleoside kinase
WSWS_RS00330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WSWS_RS00350	COG0542	response to heat
WSWS_RS00355	COG0085	RNA polymerase activity
WSWS_RS00360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WSWS_RS00380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WSWS_RS00385	COG0242	peptide deformylase activity
WSWS_RS00395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WSWS_RS00405	COG0671	phosphoesterase, PA-phosphatase related
WSWS_RS00410	COG0495	leucyl-tRNA aminoacylation
WSWS_RS00420	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WSWS_RS00425	COG3870	Protein conserved in bacteria
WSWS_RS00430	COG0470	DNA polymerase III
WSWS_RS00445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WSWS_RS00450	COG1214	PFAM Peptidase M22, glycoprotease
WSWS_RS00465	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WSWS_RS00475	COG0051	transcription antitermination factor activity, RNA binding
WSWS_RS00480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WSWS_RS00490	COG0089	rRNA binding
WSWS_RS00495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WSWS_RS00500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WSWS_RS00505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WSWS_RS00510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WSWS_RS00515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WSWS_RS00520	COG0255	Belongs to the universal ribosomal protein uL29 family
WSWS_RS00530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WSWS_RS00535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WSWS_RS00540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WSWS_RS00545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WSWS_RS00550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WSWS_RS00555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WSWS_RS00560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WSWS_RS00565	COG1841	ribosomal large subunit assembly
WSWS_RS00570	COG0200	Binds to the 23S rRNA
WSWS_RS00585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WSWS_RS00595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WSWS_RS00600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WSWS_RS00605	COG0202	RNA polymerase activity
WSWS_RS00610	COG0203	ribosomal protein L17
WSWS_RS00630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WSWS_RS00645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WSWS_RS00660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WSWS_RS00665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WSWS_RS00670	COG0215	cysteine-tRNA ligase activity
WSWS_RS00675	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
WSWS_RS00680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WSWS_RS00690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WSWS_RS00700	COG0250	Participates in transcription elongation, termination and antitermination
WSWS_RS00705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WSWS_RS00710	COG0081	regulation of translation
WSWS_RS00715	COG1956	GAF domain-containing protein
WSWS_RS00725	COG4989	oxidoreductase activity
WSWS_RS00735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WSWS_RS00740	COG0222	ribosome binding
WSWS_RS00745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WSWS_RS00750	COG2723	6-phospho-beta-galactosidase activity
WSWS_RS00755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WSWS_RS00760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WSWS_RS00765	COG1447	Phosphotransferase system cellobiose-specific component IIA
WSWS_RS00770	COG2723	6-phospho-beta-galactosidase activity
WSWS_RS00775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WSWS_RS00775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WSWS_RS00785	COG2337	Toxic component of a toxin-antitoxin (TA) module
WSWS_RS00790	COG0477	Major facilitator Superfamily
WSWS_RS00795	COG1827	regulation of RNA biosynthetic process
WSWS_RS00800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WSWS_RS00805	COG3973	AAA domain
WSWS_RS00810	COG0180	Tryptophanyl-tRNA synthetase
WSWS_RS00820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WSWS_RS00825	COG4166	transmembrane transport
WSWS_RS00830	COG2610	gluconate transmembrane transporter activity
WSWS_RS00835	COG1012	belongs to the aldehyde dehydrogenase family
WSWS_RS00835	COG1454	alcohol dehydrogenase
WSWS_RS00840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WSWS_RS00850	COG1187	pseudouridine synthase activity
WSWS_RS00855	COG1733	regulation of RNA biosynthetic process
WSWS_RS00870	COG0861	Integral membrane protein TerC family
WSWS_RS00875	COG1252	NADH dehydrogenase
WSWS_RS00885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WSWS_RS00890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
WSWS_RS00895	COG1074	ATP-dependent DNA helicase activity
WSWS_RS00900	COG1064	alcohol dehydrogenase
WSWS_RS00905	COG2814	Major facilitator Superfamily
WSWS_RS00910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WSWS_RS00920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WSWS_RS00925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WSWS_RS00930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WSWS_RS00935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WSWS_RS00945	COG0360	Binds together with S18 to 16S ribosomal RNA
WSWS_RS00950	COG0629	single-stranded DNA binding
WSWS_RS00955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WSWS_RS00960	COG0346	lactoylglutathione lyase activity
WSWS_RS00975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WSWS_RS00985	COG1122	ATPase activity
WSWS_RS00995	COG0101	tRNA pseudouridine synthase activity
WSWS_RS01000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WSWS_RS01035	COG1196	nuclear chromosome segregation
WSWS_RS01035	COG1674	ftsk spoiiie
WSWS_RS01090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WSWS_RS01100	COG1088	dTDP-glucose 4,6-dehydratase activity
WSWS_RS01115	COG0561	phosphatase activity
WSWS_RS01130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WSWS_RS01135	COG0248	Ppx GppA phosphatase
WSWS_RS01170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WSWS_RS01195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WSWS_RS01200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WSWS_RS01200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WSWS_RS01205	COG1268	BioY protein
WSWS_RS01210	COG0194	GDP metabolic process
WSWS_RS01230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WSWS_RS01235	COG0765	amino acid transport
WSWS_RS01240	COG0765	amino acid transport
WSWS_RS01245	COG4166	transmembrane transport
WSWS_RS01250	COG0601	transmembrane transport
WSWS_RS01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WSWS_RS01260	COG0444	Belongs to the ABC transporter superfamily
WSWS_RS01265	COG4608	Belongs to the ABC transporter superfamily
WSWS_RS01270	COG0475	glutathione-regulated potassium exporter activity
WSWS_RS01285	COG0359	binds to the 23S rRNA
WSWS_RS01290	COG2176	DNA-directed DNA polymerase activity
WSWS_RS01320	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
WSWS_RS01340	COG2183	response to ionizing radiation
WSWS_RS01355	COG3842	ATPase activity
WSWS_RS01365	COG1177	transmembrane transport
WSWS_RS01375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WSWS_RS01380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WSWS_RS01385	COG0459	protein refolding
WSWS_RS01390	COG1278	Cold shock
WSWS_RS01395	COG0628	permease
WSWS_RS01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WSWS_RS01410	COG1126	abc transporter atp-binding protein
WSWS_RS01415	COG3764	Sortase (surface protein transpeptidase)
WSWS_RS01425	COG0280	phosphate acetyltransferase
WSWS_RS01430	COG0305	Participates in initiation and elongation during chromosome replication
WSWS_RS01435	COG2814	Major facilitator Superfamily
WSWS_RS01460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WSWS_RS01470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WSWS_RS01475	COG2188	Transcriptional regulator
WSWS_RS01480	COG0277	FAD linked oxidase domain protein
WSWS_RS01485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WSWS_RS01490	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
WSWS_RS01495	COG3973	AAA domain
WSWS_RS01500	COG1072	(Pantothenic acid kinase))
WSWS_RS01505	COG0741	lytic transglycosylase activity
WSWS_RS01515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WSWS_RS01525	COG0589	response to stress
WSWS_RS01540	COG1272	protein, Hemolysin III
WSWS_RS01545	COG4862	establishment of competence for transformation
WSWS_RS01555	COG4120	Belongs to the binding-protein-dependent transport system permease family
WSWS_RS01560	COG1122	ATPase activity
WSWS_RS01565	COG1609	Transcriptional regulator
WSWS_RS01580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WSWS_RS01585	COG4472	Bacterial protein of unknown function (DUF965)
WSWS_RS01595	COG2246	polysaccharide biosynthetic process
WSWS_RS01600	COG3906	Belongs to the UPF0473 family
WSWS_RS01605	COG3906	Belongs to the UPF0473 family
WSWS_RS01610	COG1597	lipid kinase activity
WSWS_RS01620	COG2252	PERMEase
WSWS_RS01630	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WSWS_RS01640	COG0561	phosphatase activity
WSWS_RS01645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WSWS_RS01650	COG4589	Belongs to the CDS family
WSWS_RS01655	COG0750	zinc metalloprotease
WSWS_RS01665	COG2244	polysaccharide biosynthetic process
WSWS_RS01675	COG0442	prolyl-tRNA aminoacylation
WSWS_RS01680	COG0571	ribonuclease III activity
WSWS_RS01685	COG1196	nuclear chromosome segregation
WSWS_RS01690	COG0552	protein localization to endoplasmic reticulum
WSWS_RS01695	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
WSWS_RS01700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WSWS_RS01710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WSWS_RS01720	COG4684	Psort location CytoplasmicMembrane, score
WSWS_RS01725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
WSWS_RS01730	COG0351	phosphomethylpyrimidine kinase
WSWS_RS01735	COG0352	thiamine-phosphate diphosphorylase activity
WSWS_RS01745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WSWS_RS01755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WSWS_RS01765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WSWS_RS01770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WSWS_RS01775	COG1846	Transcriptional regulator
WSWS_RS01780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WSWS_RS01785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WSWS_RS01795	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WSWS_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
WSWS_RS01805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WSWS_RS01820	COG0439	Biotin carboxylase
WSWS_RS01825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WSWS_RS01830	COG0825	malonyl-CoA metabolic process
WSWS_RS01875	COG4485	Bacterial membrane protein, YfhO
WSWS_RS01885	COG3715	PTS system
WSWS_RS01890	COG3716	PTS system mannose fructose sorbose family IID component
WSWS_RS01900	COG2137	regulation of response to DNA damage stimulus
WSWS_RS01915	COG1132	(ABC) transporter
WSWS_RS01920	COG1132	(ABC) transporter
WSWS_RS01935	COG0006	proline dipeptidase activity
WSWS_RS01940	COG1609	Transcriptional regulator
WSWS_RS01945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WSWS_RS01950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WSWS_RS01955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WSWS_RS01960	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WSWS_RS01965	COG0047	phosphoribosylformylglycinamidine synthase activity
WSWS_RS01970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WSWS_RS01980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WSWS_RS01985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WSWS_RS01990	COG0138	bifunctional purine biosynthesis protein purh
WSWS_RS02000	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WSWS_RS02005	COG4166	transmembrane transport
WSWS_RS02010	COG1228	amidohydrolase
WSWS_RS02020	COG2807	transmembrane transport
WSWS_RS02030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WSWS_RS02050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WSWS_RS02070	COG1381	Involved in DNA repair and RecF pathway recombination
WSWS_RS02075	COG0752	glycyl-tRNA synthetase alpha subunit
WSWS_RS02080	COG0751	glycine-tRNA ligase activity
WSWS_RS02095	COG0632	four-way junction helicase activity
WSWS_RS02100	COG2255	four-way junction helicase activity
WSWS_RS02105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WSWS_RS02115	COG1862	Preprotein translocase
WSWS_RS02125	COG1307	EDD domain protein, DegV family
WSWS_RS02130	COG0446	pyridine nucleotide-disulphide oxidoreductase
WSWS_RS02145	COG0789	Transcriptional regulator
WSWS_RS02190	COG1940	carbohydrate kinase activity
WSWS_RS02195	COG0765	amino acid transport
WSWS_RS02200	COG1126	abc transporter atp-binding protein
WSWS_RS02220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WSWS_RS02235	COG1388	LysM domain
WSWS_RS02235	COG1705	Flagellar rod assembly protein muramidase FlgJ
WSWS_RS02255	COG0564	pseudouridine synthase activity
WSWS_RS02275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WSWS_RS02285	COG1472	Belongs to the glycosyl hydrolase 3 family
WSWS_RS02305	COG0833	amino acid
WSWS_RS02320	COG2723	6-phospho-beta-galactosidase activity
WSWS_RS02325	COG3711	transcriptional antiterminator
WSWS_RS02335	COG2264	protein methyltransferase activity
WSWS_RS02340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WSWS_RS02350	COG2001	Belongs to the MraZ family
WSWS_RS02355	COG0275	rRNA processing
WSWS_RS02365	COG0768	penicillin binding
WSWS_RS02370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WSWS_RS02375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WSWS_RS02380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WSWS_RS02395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WSWS_RS02400	COG1799	cell septum assembly
WSWS_RS02415	COG3599	regulation of cell shape
WSWS_RS02420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WSWS_RS02445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WSWS_RS02450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WSWS_RS02455	COG0513	Belongs to the DEAD box helicase family
WSWS_RS02460	COG0024	Methionine aminopeptidase
WSWS_RS02475	COG1164	Oligoendopeptidase f
WSWS_RS02480	COG0779	Required for maturation of 30S ribosomal subunits
WSWS_RS02485	COG0195	Participates in both transcription termination and antitermination
WSWS_RS02490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
WSWS_RS02500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WSWS_RS02505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WSWS_RS02510	COG2996	Protein conserved in bacteria
WSWS_RS02525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WSWS_RS02530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WSWS_RS02535	COG1187	pseudouridine synthase activity
WSWS_RS02540	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
WSWS_RS02550	COG0514	ATP-dependent DNA helicase (RecQ)
WSWS_RS02560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WSWS_RS02565	COG0539	negative regulation of cytoplasmic translation
WSWS_RS02570	COG1160	GTP binding
WSWS_RS02575	COG0776	regulation of translation
WSWS_RS02590	COG0242	peptide deformylase activity
WSWS_RS02600	COG0483	inositol monophosphate 1-phosphatase activity
WSWS_RS02605	COG1217	gtp-binding protein TYPA
WSWS_RS02610	COG0772	Belongs to the SEDS family
WSWS_RS02615	COG4471	UPF0298 protein
WSWS_RS02620	COG0742	ribosomal rna small subunit methyltransferase
WSWS_RS02625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WSWS_RS02630	COG3480	Lon protease (S16) C-terminal proteolytic domain
WSWS_RS02655	COG1193	negative regulation of DNA recombination
WSWS_RS02670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WSWS_RS02675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WSWS_RS02695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WSWS_RS02705	COG0018	arginyl-trna synthetase
WSWS_RS02710	COG2188	Transcriptional regulator
WSWS_RS02715	COG2190	(PTS) system
WSWS_RS02715	COG1263	PTS System
WSWS_RS02715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WSWS_RS02720	COG1263	PTS System
WSWS_RS02720	COG2190	(PTS) system
WSWS_RS02720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WSWS_RS02725	COG0366	Alpha amylase catalytic
WSWS_RS02740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WSWS_RS02740	COG2169	Transcriptional regulator
WSWS_RS02750	COG1230	cation diffusion facilitator family transporter
WSWS_RS02755	COG2814	Major facilitator Superfamily
WSWS_RS02785	COG4619	ABC transporter
WSWS_RS02790	COG0390	transport system, permease component
WSWS_RS02805	COG0463	Glycosyl transferase, family 2
WSWS_RS02810	COG1215	transferase activity, transferring glycosyl groups
WSWS_RS02815	COG1134	teichoic acid transport
WSWS_RS02815	COG1388	LysM domain
WSWS_RS02820	COG1682	transport, permease protein
WSWS_RS02835	COG0351	phosphomethylpyrimidine kinase
WSWS_RS02845	COG2814	Major facilitator Superfamily
WSWS_RS02860	COG4474	Belongs to the UPF0398 family
WSWS_RS02865	COG3599	regulation of cell shape
WSWS_RS02875	COG0670	Belongs to the BI1 family
WSWS_RS02880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WSWS_RS02880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WSWS_RS02885	COG1234	tRNA 3'-trailer cleavage
WSWS_RS02890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
WSWS_RS02890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WSWS_RS02900	COG0124	histidyl-tRNA synthetase
WSWS_RS02905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WSWS_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WSWS_RS02920	COG0588	phosphoglycerate mutase activity
WSWS_RS02930	COG0105	UTP biosynthetic process
WSWS_RS02935	COG0217	transcriptional regulatory protein
WSWS_RS02940	COG1979	alcohol dehydrogenase
WSWS_RS02950	COG4166	transmembrane transport
WSWS_RS02955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WSWS_RS02965	COG1304	FMN binding
WSWS_RS02985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WSWS_RS02985	COG1199	ATP-dependent helicase activity
WSWS_RS02995	COG0017	Asparaginyl-tRNA synthetase
WSWS_RS03010	COG0617	tRNA 3'-terminal CCA addition
WSWS_RS03015	COG0488	(ABC) transporter
WSWS_RS03030	COG0587	DNA-directed DNA polymerase activity
WSWS_RS03040	COG2936	dipeptidyl-peptidase activity
WSWS_RS03050	COG0745	RESPONSE REGULATOR receiver
WSWS_RS03055	COG5002	protein histidine kinase activity
WSWS_RS03060	COG0572	uridine kinase
WSWS_RS03065	COG1363	Peptidase, m42
WSWS_RS03070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WSWS_RS03090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WSWS_RS03095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WSWS_RS03100	COG0237	dephospho-CoA kinase activity
WSWS_RS03110	COG1484	DNA-dependent DNA replication
WSWS_RS03125	COG0745	RESPONSE REGULATOR receiver
WSWS_RS03130	COG5002	protein histidine kinase activity
WSWS_RS03135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WSWS_RS03155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WSWS_RS03160	COG1610	YqeY-like protein
WSWS_RS03165	COG1702	phosphate starvation-inducible protein PhoH
WSWS_RS03170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WSWS_RS03175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WSWS_RS03180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WSWS_RS03185	COG0196	riboflavin kinase activity
WSWS_RS03195	COG3142	Participates in the control of copper homeostasis
WSWS_RS03210	COG1307	EDD domain protein, DegV family
WSWS_RS03215	COG1307	EDD domain protein, DegV family
WSWS_RS03220	COG2755	lipolytic protein G-D-S-L family
WSWS_RS03230	COG4479	Belongs to the UPF0346 family
WSWS_RS03245	COG1472	Belongs to the glycosyl hydrolase 3 family
WSWS_RS03305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WSWS_RS03310	COG0758	DNA mediated transformation
WSWS_RS03315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WSWS_RS03320	COG4974	Belongs to the 'phage' integrase family
WSWS_RS03335	COG0187	DNA topoisomerase II activity
WSWS_RS03340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WSWS_RS03345	COG0481	GTPase activity
WSWS_RS03350	COG0116	Belongs to the methyltransferase superfamily
WSWS_RS03360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WSWS_RS03370	COG1279	arginine transmembrane transporter activity
WSWS_RS03380	COG0556	nucleotide-excision repair
WSWS_RS03390	COG0537	adenosine 5'-monophosphoramidase activity
WSWS_RS03395	COG1131	(ABC) transporter
WSWS_RS03405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WSWS_RS03420	COG0438	transferase activity, transferring glycosyl groups
WSWS_RS03430	COG2223	nitrite transmembrane transporter activity
WSWS_RS03435	COG0095	Lipoate-protein ligase
WSWS_RS03470	COG0346	lactoylglutathione lyase activity
WSWS_RS03490	COG1028	Short-chain dehydrogenase reductase Sdr
WSWS_RS03525	COG1136	(ABC) transporter
WSWS_RS03530	COG0577	efflux transmembrane transporter activity
WSWS_RS03535	COG2197	response regulator
WSWS_RS03540	COG4585	Histidine kinase
WSWS_RS03545	COG2409	Drug exporters of the RND superfamily
WSWS_RS03550	COG0789	Transcriptional regulator
WSWS_RS03565	COG0656	L-ascorbic acid biosynthetic process
WSWS_RS03590	COG0431	NADPH-dependent FMN reductase
WSWS_RS03600	COG4221	oxidoreductase activity
WSWS_RS03610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WSWS_RS03615	COG0789	Transcriptional regulator
WSWS_RS03625	COG1942	4-Oxalocrotonate Tautomerase
WSWS_RS03630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WSWS_RS03630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WSWS_RS03630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WSWS_RS03635	COG1105	Belongs to the carbohydrate kinase PfkB family
WSWS_RS03640	COG1349	DNA-binding transcription factor activity
WSWS_RS03655	COG1131	(ABC) transporter
WSWS_RS03665	COG0318	PFAM AMP-dependent synthetase and ligase
WSWS_RS03670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WSWS_RS03680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WSWS_RS03685	COG0318	PFAM AMP-dependent synthetase and ligase
WSWS_RS03690	COG0494	nUDIX hydrolase
WSWS_RS03700	COG1490	D-aminoacyl-tRNA deacylase activity
WSWS_RS03705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WSWS_RS03710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WSWS_RS03715	COG0358	DNA primase activity
WSWS_RS03720	COG2070	2-Nitropropane dioxygenase
WSWS_RS03730	COG0583	DNA-binding transcription factor activity
WSWS_RS03735	COG2274	protein secretion by the type I secretion system
WSWS_RS03740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WSWS_RS03745	COG2723	6-phospho-beta-galactosidase activity
WSWS_RS03750	COG2188	Transcriptional regulator
WSWS_RS03765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
WSWS_RS03770	COG1733	regulation of RNA biosynthetic process
WSWS_RS03790	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WSWS_RS03810	COG2211	Major facilitator Superfamily
WSWS_RS03830	COG2966	Psort location CytoplasmicMembrane, score
WSWS_RS03835	COG1473	amidohydrolase
WSWS_RS03840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WSWS_RS03860	COG1609	Transcriptional regulator
WSWS_RS03885	COG4175	Glycine betaine
WSWS_RS03885	COG3448	diguanylate cyclase activity
WSWS_RS03895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WSWS_RS03900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WSWS_RS03910	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
WSWS_RS03930	COG1506	peptidase
WSWS_RS03930	COG4946	Tricorn protease homolog
WSWS_RS03930	COG0823	Involved in the tonB-independent uptake of proteins
WSWS_RS03935	COG0268	Binds directly to 16S ribosomal RNA
WSWS_RS03940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WSWS_RS03945	COG1466	dna polymerase III delta subunit
WSWS_RS03955	COG1596	polysaccharide export
WSWS_RS03955	COG1555	photosystem II stabilization
WSWS_RS03980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WSWS_RS03985	COG5632	N-Acetylmuramoyl-L-alanine amidase
WSWS_RS03985	COG4193	domain, Protein
WSWS_RS03985	COG3266	domain, Protein
WSWS_RS03990	COG3942	CHAP domain
WSWS_RS03990	COG1705	Flagellar rod assembly protein muramidase FlgJ
WSWS_RS04005	COG2814	Major facilitator Superfamily
WSWS_RS04010	COG0477	Major facilitator Superfamily
WSWS_RS04015	COG3883	PFAM NLP P60 protein
WSWS_RS04015	COG0791	NLP P60 protein
WSWS_RS04020	COG3048	D-serine ammonia-lyase activity
WSWS_RS04025	COG1739	Uncharacterized protein family UPF0029
WSWS_RS04035	COG5503	Protein of unknown function (DUF1447)
WSWS_RS04060	COG4224	UPF0291 protein
WSWS_RS04065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WSWS_RS04080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WSWS_RS04085	COG2384	SAM-dependent methyltransferase
WSWS_RS04090	COG1597	lipid kinase activity
WSWS_RS04100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WSWS_RS04105	COG0601	transmembrane transport
WSWS_RS04110	COG4608	Belongs to the ABC transporter superfamily
WSWS_RS04115	COG0444	Belongs to the ABC transporter superfamily
WSWS_RS04120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WSWS_RS04135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WSWS_RS04140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WSWS_RS04155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WSWS_RS04165	COG0052	Belongs to the universal ribosomal protein uS2 family
WSWS_RS04170	COG2827	Endonuclease containing a URI domain
WSWS_RS04175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WSWS_RS04180	COG0204	Acyl-transferase
WSWS_RS04185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WSWS_RS04190	COG0322	excinuclease ABC activity
WSWS_RS04200	COG1126	abc transporter atp-binding protein
WSWS_RS04210	COG1674	ftsk spoiiie
WSWS_RS04220	COG0628	permease
WSWS_RS04225	COG2706	6-phosphogluconolactonase activity
WSWS_RS04235	COG0436	Aminotransferase
WSWS_RS04240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WSWS_RS04245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WSWS_RS04250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WSWS_RS04255	COG1473	amidohydrolase
WSWS_RS04260	COG2171	N-acyltransferase activity
WSWS_RS04270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WSWS_RS04275	COG0527	aspartate kinase activity
WSWS_RS04290	COG0393	Putative heavy-metal-binding
WSWS_RS04295	COG0110	maltose O-acetyltransferase activity
WSWS_RS04325	COG0561	phosphatase activity
WSWS_RS04335	COG1428	Deoxynucleoside kinase
WSWS_RS04345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WSWS_RS04350	COG1942	4-Oxalocrotonate Tautomerase
WSWS_RS04355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WSWS_RS04360	COG0335	large ribosomal subunit rRNA binding
WSWS_RS04370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WSWS_RS04375	COG1546	Belongs to the CinA family
WSWS_RS04375	COG1058	Belongs to the CinA family
WSWS_RS04390	COG2814	Major facilitator Superfamily
WSWS_RS04395	COG0564	pseudouridine synthase activity
WSWS_RS04400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WSWS_RS04405	COG2357	RelA SpoT domain protein
WSWS_RS04410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
WSWS_RS04415	COG0562	UDP-galactopyranose mutase
WSWS_RS04420	COG1216	Glycosyl transferase, family 2
WSWS_RS04425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WSWS_RS04430	COG0154	amidase activity
WSWS_RS04435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WSWS_RS04440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WSWS_RS04440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WSWS_RS04445	COG0561	phosphatase activity
WSWS_RS04450	COG0667	Aldo Keto reductase
WSWS_RS04455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WSWS_RS04460	COG0167	dihydroorotate dehydrogenase activity
WSWS_RS04470	COG1122	ATPase activity
WSWS_RS04490	COG0706	membrane insertase activity
WSWS_RS04500	COG1335	isochorismatase
WSWS_RS04505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WSWS_RS04510	COG0516	GMP reductase activity
WSWS_RS04510	COG0517	IMP dehydrogenase activity
WSWS_RS04515	COG0400	carboxylic ester hydrolase activity
WSWS_RS04520	COG0346	lactoylglutathione lyase activity
WSWS_RS04545	COG2261	transglycosylase associated protein
WSWS_RS04555	COG5001	Diguanylate cyclase
WSWS_RS04560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WSWS_RS04595	COG5280	Phage tail tape measure protein TP901
WSWS_RS04595	COG3953	SLT domain
WSWS_RS04665	COG1573	uracil-dna glycosylase
WSWS_RS04680	COG0110	maltose O-acetyltransferase activity
WSWS_RS04715	COG3723	Recombinational DNA repair protein, rece pathway
WSWS_RS04760	COG1396	sequence-specific DNA binding
WSWS_RS04810	COG5001	Diguanylate cyclase
WSWS_RS04825	COG2514	catechol 2,3-dioxygenase activity
WSWS_RS04850	COG2199	diguanylate cyclase activity
WSWS_RS04855	COG5002	protein histidine kinase activity
WSWS_RS04865	COG1017	nitric oxide dioxygenase activity
WSWS_RS04865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WSWS_RS04875	COG1131	(ABC) transporter
WSWS_RS04890	COG0741	lytic transglycosylase activity
WSWS_RS04900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WSWS_RS04910	COG1668	transmembrane transport
WSWS_RS04915	COG4152	abc transporter atp-binding protein
WSWS_RS04920	COG0525	valine-tRNA ligase activity
WSWS_RS04925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WSWS_RS04945	COG1607	acyl-coa hydrolase
WSWS_RS04955	COG0330	HflC and HflK could
WSWS_RS04980	COG2261	transglycosylase associated protein
WSWS_RS04985	COG0228	four-way junction DNA binding
WSWS_RS04990	COG0584	glycerophosphoryl diester phosphodiesterase
WSWS_RS04995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WSWS_RS05000	COG0531	amino acid
WSWS_RS05010	COG1077	Cell shape determining protein MreB Mrl
WSWS_RS05015	COG2003	Belongs to the UPF0758 family
WSWS_RS05030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WSWS_RS05040	COG0494	nUDIX hydrolase
WSWS_RS05045	COG1278	Cold shock
WSWS_RS05055	COG1744	ABC transporter substrate-binding protein PnrA-like
WSWS_RS05060	COG1132	(ABC) transporter
WSWS_RS05065	COG1132	(ABC) transporter
WSWS_RS05075	COG4720	Psort location CytoplasmicMembrane, score
WSWS_RS05080	COG0564	pseudouridine synthase activity
WSWS_RS05085	COG0604	alcohol dehydrogenase
WSWS_RS05090	COG0436	Aminotransferase
WSWS_RS05100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WSWS_RS05105	COG1757	Na H antiporter
WSWS_RS05115	COG1121	(ABC) transporter
WSWS_RS05125	COG1846	Transcriptional regulator
WSWS_RS05140	COG1940	carbohydrate kinase activity
WSWS_RS05145	COG2190	(PTS) system
WSWS_RS05145	COG2211	Major facilitator Superfamily
WSWS_RS05155	COG1464	Belongs to the NlpA lipoprotein family
WSWS_RS05185	COG0656	L-ascorbic acid biosynthetic process
WSWS_RS05200	COG2160	L-arabinose isomerase activity
WSWS_RS05215	COG1609	Transcriptional regulator
WSWS_RS05220	COG1940	carbohydrate kinase activity
WSWS_RS05225	COG1621	beta-fructofuranosidase activity
WSWS_RS05235	COG1609	Transcriptional regulator
WSWS_RS05245	COG0697	spore germination
WSWS_RS05255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WSWS_RS05260	COG0004	ammonium transporteR
WSWS_RS05265	COG0860	N-Acetylmuramoyl-L-alanine amidase
WSWS_RS05275	COG0306	phosphate transporter
WSWS_RS05280	COG0028	Belongs to the TPP enzyme family
WSWS_RS05290	COG1914	H( )-stimulated, divalent metal cation uptake system
WSWS_RS05295	COG3477	response to acidic pH
WSWS_RS05315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WSWS_RS05320	COG0719	Fe-S assembly protein
WSWS_RS05330	COG0602	queuosine metabolic process
WSWS_RS05340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WSWS_RS05350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WSWS_RS05355	COG3425	synthase
WSWS_RS05360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WSWS_RS05375	COG0626	cystathionine gamma-synthase activity
WSWS_RS05390	COG0443	Heat shock 70 kDa protein
WSWS_RS05395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WSWS_RS05400	COG1420	regulation of RNA biosynthetic process
WSWS_RS05415	COG1309	transcriptional regulator
WSWS_RS05420	COG0419	ATPase involved in DNA repair
WSWS_RS05435	COG1970	mechanosensitive ion channel activity
WSWS_RS05440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WSWS_RS05445	COG1426	Protein conserved in bacteria
WSWS_RS05450	COG0612	Peptidase, M16
WSWS_RS05455	COG0612	Peptidase, M16
WSWS_RS05460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WSWS_RS05465	COG1368	sulfuric ester hydrolase activity
WSWS_RS05480	COG0438	transferase activity, transferring glycosyl groups
WSWS_RS05485	COG0438	transferase activity, transferring glycosyl groups
WSWS_RS05490	COG0363	glucosamine-6-phosphate deaminase activity
WSWS_RS05495	COG1070	Carbohydrate kinase
WSWS_RS05500	COG3481	metal-dependent phosphohydrolase, HD sub domain
WSWS_RS05510	COG3679	Belongs to the UPF0342 family
WSWS_RS05515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WSWS_RS05520	COG1438	arginine binding
WSWS_RS05530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WSWS_RS05535	COG3853	Toxic anion resistance protein (TelA)
WSWS_RS05555	COG1113	amino acid transport
WSWS_RS05565	COG0254	rRNA binding
WSWS_RS05575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WSWS_RS05580	COG0284	orotidine-5'-phosphate decarboxylase activity
WSWS_RS05585	COG0167	dihydroorotate dehydrogenase activity
WSWS_RS05590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WSWS_RS05595	COG0505	Belongs to the CarA family
WSWS_RS05605	COG0540	Belongs to the ATCase OTCase family
WSWS_RS05615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WSWS_RS05620	COG4856	YbbR-like protein
WSWS_RS05635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WSWS_RS05650	COG0802	atpase or kinase
WSWS_RS05655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WSWS_RS05660	COG0416	fatty acid biosynthetic process
WSWS_RS05665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WSWS_RS05670	COG1461	Dihydroxyacetone kinase
WSWS_RS05680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WSWS_RS05690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WSWS_RS05695	COG1162	GTPase activity
WSWS_RS05700	COG2815	serine threonine protein kinase
WSWS_RS05700	COG0515	serine threonine protein kinase
WSWS_RS05705	COG0631	protein serine/threonine phosphatase activity
WSWS_RS05710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WSWS_RS05710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WSWS_RS05715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WSWS_RS05720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WSWS_RS05725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WSWS_RS05750	COG4537	Required for transformation and DNA binding
WSWS_RS05760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WSWS_RS05765	COG2252	PERMEase
WSWS_RS05770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WSWS_RS05780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WSWS_RS05785	COG4988	ABC transporter
WSWS_RS05790	COG1294	oxidase, subunit
WSWS_RS05795	COG1271	oxidase subunit
WSWS_RS05905	COG1098	S1 RNA binding domain
WSWS_RS05915	COG0586	Pfam SNARE associated Golgi protein
WSWS_RS05930	COG1758	RNA polymerase activity
WSWS_RS05935	COG0194	GDP metabolic process
WSWS_RS05945	COG0497	DNA recombination
WSWS_RS05950	COG1438	arginine binding
WSWS_RS05955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WSWS_RS05960	COG0142	geranyltranstransferase activity
WSWS_RS05970	COG1570	exodeoxyribonuclease VII activity
WSWS_RS05975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WSWS_RS05985	COG1122	ATPase activity
WSWS_RS05990	COG4720	Psort location CytoplasmicMembrane, score
WSWS_RS06005	COG0488	(ABC) transporter
WSWS_RS06010	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
WSWS_RS06015	COG0513	Belongs to the DEAD box helicase family
WSWS_RS06020	COG0673	inositol 2-dehydrogenase activity
WSWS_RS06025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WSWS_RS06035	COG1323	Belongs to the UPF0348 family
WSWS_RS06040	COG2226	methyltransferase
WSWS_RS06045	COG0799	negative regulation of ribosome biogenesis
WSWS_RS06050	COG1713	HD superfamily hydrolase involved in NAD metabolism
WSWS_RS06055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WSWS_RS06065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WSWS_RS06080	COG0126	phosphoglycerate kinase activity
WSWS_RS06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WSWS_RS06130	COG0149	triose-phosphate isomerase activity
WSWS_RS06135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WSWS_RS06140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WSWS_RS06145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WSWS_RS06150	COG0492	ferredoxin-NADP+ reductase activity
WSWS_RS06155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WSWS_RS06160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WSWS_RS06165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WSWS_RS06170	COG1950	PFAM Membrane protein of
WSWS_RS06175	COG0589	response to stress
WSWS_RS06185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WSWS_RS06190	COG0049	tRNA binding
WSWS_RS06195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WSWS_RS06205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WSWS_RS06210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WSWS_RS06215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WSWS_RS06225	COG1302	Protein conserved in bacteria
WSWS_RS06230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WSWS_RS06235	COG0166	Belongs to the GPI family
WSWS_RS06240	COG2017	converts alpha-aldose to the beta-anomer
WSWS_RS06245	COG4975	Glucose uptake
WSWS_RS06250	COG5002	protein histidine kinase activity
WSWS_RS06250	COG3850	Histidine kinase
WSWS_RS06255	COG0745	RESPONSE REGULATOR receiver
WSWS_RS06260	COG0765	amino acid transport
WSWS_RS06265	COG0402	S-adenosylhomocysteine deaminase activity
WSWS_RS06280	COG2217	Heavy metal translocating P-type atpase
WSWS_RS06295	COG2217	Heavy metal translocating P-type atpase
WSWS_RS06305	COG0604	alcohol dehydrogenase
WSWS_RS06325	COG0557	exoribonuclease II activity
WSWS_RS06335	COG0647	UMP catabolic process
WSWS_RS06345	COG0737	Belongs to the 5'-nucleotidase family
WSWS_RS06360	COG0006	proline dipeptidase activity
WSWS_RS06370	COG0596	Alpha beta hydrolase
WSWS_RS06375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WSWS_RS06380	COG1169	isochorismate synthase
WSWS_RS06400	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WSWS_RS06450	COG0789	Transcriptional regulator
WSWS_RS06455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WSWS_RS06475	COG1940	carbohydrate kinase activity
WSWS_RS06490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WSWS_RS06495	COG0768	penicillin binding
WSWS_RS06500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WSWS_RS06510	COG0704	Plays a role in the regulation of phosphate uptake
WSWS_RS06515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WSWS_RS06525	COG0581	inorganic phosphate transmembrane transporter activity
WSWS_RS06530	COG0573	inorganic phosphate transmembrane transporter activity
WSWS_RS06550	COG1136	(ABC) transporter
WSWS_RS06550	COG0577	efflux transmembrane transporter activity
WSWS_RS06565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WSWS_RS06570	COG0772	Belongs to the SEDS family
WSWS_RS06580	COG1077	Cell shape determining protein MreB Mrl
WSWS_RS06585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WSWS_RS06590	COG1136	(ABC) transporter
WSWS_RS06595	COG0577	efflux transmembrane transporter activity
WSWS_RS06600	COG1079	Belongs to the binding-protein-dependent transport system permease family
WSWS_RS06605	COG4603	Belongs to the binding-protein-dependent transport system permease family
WSWS_RS06610	COG3845	ABC transporter
WSWS_RS06615	COG0588	phosphoglycerate mutase activity
WSWS_RS06620	COG0492	ferredoxin-NADP+ reductase activity
WSWS_RS06625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WSWS_RS06630	COG0072	phenylalanine-tRNA ligase activity
WSWS_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WSWS_RS06635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WSWS_RS06640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WSWS_RS06645	COG4956	integral membrane protein (PIN domain superfamily)
WSWS_RS06655	COG0756	dUTP diphosphatase activity
WSWS_RS06670	COG1388	LysM domain
WSWS_RS06670	COG3942	CHAP domain
WSWS_RS06675	COG0542	response to heat
WSWS_RS06705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WSWS_RS06710	COG0740	serine-type endopeptidase activity
WSWS_RS06715	COG1481	regulation of sporulation
WSWS_RS06725	COG1660	Displays ATPase and GTPase activities
WSWS_RS06730	COG3507	Belongs to the glycosyl hydrolase 43 family
WSWS_RS06745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WSWS_RS06750	COG0653	protein targeting
WSWS_RS06755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WSWS_RS06760	COG3442	glutamine amidotransferase
WSWS_RS06765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WSWS_RS06770	COG1482	cell wall glycoprotein biosynthetic process
WSWS_RS06795	COG1132	(ABC) transporter
WSWS_RS06800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WSWS_RS06815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WSWS_RS06825	COG0561	phosphatase activity
WSWS_RS06830	COG1078	dGTPase activity
WSWS_RS06840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WSWS_RS06845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WSWS_RS06860	COG5002	protein histidine kinase activity
WSWS_RS06865	COG0745	RESPONSE REGULATOR receiver
WSWS_RS06875	COG3590	peptidase
WSWS_RS06895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WSWS_RS06905	COG3104	oligopeptide transport
WSWS_RS06915	COG2813	Specifically methylates the guanine in position
WSWS_RS06940	COG0500	methyltransferase
WSWS_RS06950	COG1121	(ABC) transporter
WSWS_RS06975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WSWS_RS06980	COG0336	Belongs to the RNA methyltransferase TrmD family
WSWS_RS06990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WSWS_RS07005	COG1959	2 iron, 2 sulfur cluster binding
WSWS_RS07010	COG0702	epimerase
WSWS_RS07075	COG0438	transferase activity, transferring glycosyl groups
WSWS_RS07080	COG0438	transferase activity, transferring glycosyl groups
WSWS_RS07085	COG2084	Dehydrogenase
WSWS_RS07090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WSWS_RS07095	COG2233	PERMEase
WSWS_RS07100	COG1744	ABC transporter substrate-binding protein PnrA-like
WSWS_RS07105	COG2252	PERMEase
WSWS_RS07110	COG0504	CTP synthase activity
WSWS_RS07115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WSWS_RS07125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WSWS_RS07130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WSWS_RS07135	COG1737	Transcriptional regulator
WSWS_RS07150	COG0626	cystathionine gamma-synthase activity
WSWS_RS07155	COG1464	Belongs to the NlpA lipoprotein family
WSWS_RS07160	COG1854	S-ribosylhomocysteine lyase activity
WSWS_RS07165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WSWS_RS07175	COG1473	amidohydrolase
WSWS_RS07180	COG3118	belongs to the thioredoxin family
WSWS_RS07220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WSWS_RS07225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WSWS_RS07230	COG3527	Alpha-acetolactate decarboxylase
WSWS_RS07235	COG0028	Belongs to the TPP enzyme family
WSWS_RS07260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WSWS_RS07265	COG2244	polysaccharide biosynthetic process
WSWS_RS07270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WSWS_RS07275	COG0193	aminoacyl-tRNA hydrolase activity
WSWS_RS07295	COG2115	Belongs to the xylose isomerase family
WSWS_RS07300	COG0640	Transcriptional regulator
WSWS_RS07325	COG2211	Major facilitator Superfamily
WSWS_RS07340	COG1968	undecaprenyl-diphosphatase activity
WSWS_RS07365	COG0395	ABC-type sugar transport system, permease component
WSWS_RS07375	COG3842	ATPase activity
WSWS_RS07380	COG0737	Belongs to the 5'-nucleotidase family
WSWS_RS07385	COG1316	TRANSCRIPTIONal
WSWS_RS07390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WSWS_RS07395	COG2131	deaminase
WSWS_RS07405	COG1253	flavin adenine dinucleotide binding
WSWS_RS07410	COG1253	flavin adenine dinucleotide binding
WSWS_RS07415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WSWS_RS07425	COG0084	hydrolase, TatD family'
WSWS_RS07430	COG2855	membrane
WSWS_RS07435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WSWS_RS07450	COG1113	amino acid transport
WSWS_RS07475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WSWS_RS07480	COG1609	Transcriptional regulator
WSWS_RS07485	COG2211	Major facilitator Superfamily
WSWS_RS07485	COG2190	(PTS) system
WSWS_RS07490	COG3250	beta-galactosidase activity
WSWS_RS07495	COG0436	Aminotransferase
WSWS_RS07505	COG3475	LICD family
WSWS_RS07510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WSWS_RS07520	COG0110	maltose O-acetyltransferase activity
WSWS_RS07530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WSWS_RS07530	COG0463	Glycosyl transferase, family 2
WSWS_RS07550	COG1682	transport, permease protein
WSWS_RS07555	COG1134	teichoic acid transport
WSWS_RS07570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WSWS_RS07570	COG0463	Glycosyl transferase, family 2
WSWS_RS07575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WSWS_RS07575	COG0463	Glycosyl transferase, family 2
WSWS_RS07580	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WSWS_RS07630	COG1368	sulfuric ester hydrolase activity
WSWS_RS07650	COG0187	DNA topoisomerase II activity
WSWS_RS07655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WSWS_RS07660	COG2501	S4 domain
WSWS_RS07665	COG0586	Pfam SNARE associated Golgi protein
WSWS_RS07675	COG0592	DNA-directed DNA polymerase activity
WSWS_RS07680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WSWS_RS07685	COG0594	ribonuclease P activity
WSWS_RS07690	COG0706	membrane insertase activity
WSWS_RS07720	COG2801	Transposase and inactivated derivatives
WSWS_RS07755	COG1254	Belongs to the acylphosphatase family
WSWS_RS07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WSWS_RS07765	COG0765	amino acid transport
WSWS_RS07770	COG1126	abc transporter atp-binding protein
WSWS_RS07775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WSWS_RS07775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WSWS_RS07780	COG0681	Belongs to the peptidase S26 family
WSWS_RS07785	COG0569	domain protein
WSWS_RS07795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WSWS_RS07800	COG0561	phosphatase activity
WSWS_RS07810	COG0436	Aminotransferase
WSWS_RS07815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WSWS_RS07835	COG0328	RNA-DNA hybrid ribonuclease activity
WSWS_RS07840	COG1846	Transcriptional regulator
WSWS_RS07870	COG1511	domain protein
WSWS_RS07880	COG0277	FAD linked oxidase domain protein
WSWS_RS07885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WSWS_RS07900	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WSWS_RS07910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WSWS_RS07910	COG0519	Catalyzes the synthesis of GMP from XMP
WSWS_RS07915	COG2211	Major facilitator Superfamily
WSWS_RS07920	COG3940	Belongs to the glycosyl hydrolase 43 family
WSWS_RS07935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WSWS_RS07940	COG4166	transmembrane transport
WSWS_RS07945	COG0656	L-ascorbic acid biosynthetic process
WSWS_RS07950	COG1309	transcriptional regulator
WSWS_RS07960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WSWS_RS07965	COG0531	amino acid
WSWS_RS07980	COG0628	permease
WSWS_RS07985	COG2309	aminopeptidase activity
WSWS_RS07995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WSWS_RS08000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WSWS_RS08010	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WSWS_RS08015	COG0531	amino acid
WSWS_RS08020	COG0252	asparaginase activity
WSWS_RS08025	COG4443	Transcriptional Coactivator p15 (PC4)
WSWS_RS08030	COG2226	methyltransferase
WSWS_RS08035	COG2050	protein possibly involved in aromatic compounds catabolism
WSWS_RS08040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WSWS_RS08045	COG0318	PFAM AMP-dependent synthetase and ligase
WSWS_RS08050	COG0745	RESPONSE REGULATOR receiver
WSWS_RS08055	COG5002	protein histidine kinase activity
WSWS_RS08060	COG1881	PFAM PEBP family protein
WSWS_RS08070	COG0514	ATP-dependent DNA helicase (RecQ)
WSWS_RS08075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WSWS_RS08080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WSWS_RS08085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WSWS_RS08090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WSWS_RS08125	COG2801	Transposase and inactivated derivatives
WSWS_RS08130	COG0741	lytic transglycosylase activity
WSWS_RS08140	COG0230	Belongs to the bacterial ribosomal protein bL34 family