locus-tag	class	description
L1879_RS00015	COG2258	MOSC domain
L1879_RS00025	COG0352	thiamine-phosphate diphosphorylase activity
L1879_RS00030	COG0351	phosphomethylpyrimidine kinase
L1879_RS00035	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
L1879_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS00050	COG0456	acetyltransferase
L1879_RS00070	COG0681	Belongs to the peptidase S26 family
L1879_RS00075	COG2070	2-Nitropropane dioxygenase
L1879_RS00100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L1879_RS00100	COG0574	Belongs to the PEP-utilizing enzyme family
L1879_RS00105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
L1879_RS00120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L1879_RS00125	COG0187	DNA topoisomerase II activity
L1879_RS00130	COG1832	CoA-binding protein
L1879_RS00135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
L1879_RS00140	COG4841	protein insertion into membrane
L1879_RS00150	COG0824	Thioesterase
L1879_RS00170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L1879_RS00180	COG2309	aminopeptidase activity
L1879_RS00205	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS00210	COG1346	cytolysis
L1879_RS00215	COG1380	Effector of murein hydrolase LrgA
L1879_RS00225	COG1132	(ABC) transporter
L1879_RS00230	COG1132	(ABC) transporter
L1879_RS00240	COG0477	Major facilitator Superfamily
L1879_RS00255	COG1113	amino acid transport
L1879_RS00265	COG5039	Polysaccharide pyruvyl transferase
L1879_RS00270	COG0745	RESPONSE REGULATOR receiver
L1879_RS00275	COG0642	Histidine kinase
L1879_RS00280	COG1136	(ABC) transporter
L1879_RS00285	COG0577	efflux transmembrane transporter activity
L1879_RS00300	COG3634	alkyl hydroperoxide reductase activity
L1879_RS00305	COG0302	gtp cyclohydrolase
L1879_RS00310	COG1278	Cold shock
L1879_RS00320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1879_RS00330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L1879_RS00335	COG2807	transmembrane transport
L1879_RS00355	COG0569	domain protein
L1879_RS00360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1879_RS00365	COG2962	Rard protein
L1879_RS00370	COG2391	methyltransferase activity
L1879_RS00380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L1879_RS00380	COG0140	phosphoribosyl-ATP diphosphatase activity
L1879_RS00385	COG0107	imidazoleglycerol-phosphate synthase activity
L1879_RS00395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L1879_RS00400	COG0131	Imidazoleglycerol-phosphate dehydratase
L1879_RS00405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L1879_RS00410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L1879_RS00415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
L1879_RS00425	COG0598	Magnesium transport protein CorA
L1879_RS00430	COG1113	amino acid transport
L1879_RS00435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L1879_RS00440	COG1388	LysM domain
L1879_RS00440	COG3584	3D domain protein
L1879_RS00445	COG0723	plastoquinol--plastocyanin reductase activity
L1879_RS00445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1879_RS00450	COG0516	GMP reductase activity
L1879_RS00450	COG0517	IMP dehydrogenase activity
L1879_RS00455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1879_RS00465	COG2135	peptidase activity
L1879_RS00470	COG1054	Belongs to the UPF0176 family
L1879_RS00480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1879_RS00495	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS00500	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1879_RS00505	COG0567	Dehydrogenase, E1 component
L1879_RS00515	COG5002	protein histidine kinase activity
L1879_RS00520	COG0745	RESPONSE REGULATOR receiver
L1879_RS00525	COG2814	Major facilitator Superfamily
L1879_RS00530	COG1331	Highly conserved protein containing a thioredoxin domain
L1879_RS00535	COG1368	sulfuric ester hydrolase activity
L1879_RS00540	COG0671	phosphoesterase, PA-phosphatase related
L1879_RS00545	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
L1879_RS00550	COG3285	dna ligase
L1879_RS00550	COG1793	dna ligase
L1879_RS00555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
L1879_RS00565	COG0534	Mate efflux family protein
L1879_RS00570	COG2340	Cysteine-rich secretory protein family
L1879_RS00575	COG1846	Transcriptional regulator
L1879_RS00580	COG3409	Peptidoglycan-binding domain 1 protein
L1879_RS00580	COG0793	Belongs to the peptidase S41A family
L1879_RS00585	COG1876	peptidase activity
L1879_RS00600	COG4479	Belongs to the UPF0346 family
L1879_RS00605	COG0840	transmembrane signaling receptor activity
L1879_RS00615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1879_RS00620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1879_RS00625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1879_RS00625	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
L1879_RS00635	COG2755	lipolytic protein G-D-S-L family
L1879_RS00640	COG1272	protein, Hemolysin III
L1879_RS00645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L1879_RS00650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
L1879_RS00665	COG1413	lyase activity
L1879_RS00670	COG0488	(ABC) transporter
L1879_RS00680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
L1879_RS00685	COG1321	iron dependent repressor
L1879_RS00705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1879_RS00710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L1879_RS00715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L1879_RS00720	COG0464	growth
L1879_RS00730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
L1879_RS00750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L1879_RS00755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
L1879_RS00765	COG4550	Control of competence regulator ComK, YlbF/YmcA
L1879_RS00770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L1879_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS00785	COG3829	transcription factor binding
L1879_RS00790	COG0531	amino acid
L1879_RS00795	COG0826	peptidase U32
L1879_RS00800	COG0826	peptidase U32
L1879_RS00805	COG2359	stage V sporulation protein S
L1879_RS00810	COG1692	metallophosphoesterase
L1879_RS00815	COG1418	mRNA catabolic process
L1879_RS00825	COG1546	Belongs to the CinA family
L1879_RS00825	COG1058	Belongs to the CinA family
L1879_RS00830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L1879_RS00835	COG1426	Protein conserved in bacteria
L1879_RS00850	COG0300	oxidoreductase activity
L1879_RS00855	COG0612	Peptidase, M16
L1879_RS00860	COG0612	Peptidase, M16
L1879_RS00865	COG1079	Belongs to the binding-protein-dependent transport system permease family
L1879_RS00870	COG4603	Belongs to the binding-protein-dependent transport system permease family
L1879_RS00875	COG3845	ABC transporter
L1879_RS00880	COG1744	ABC transporter substrate-binding protein PnrA-like
L1879_RS00885	COG4980	gas vesicle protein
L1879_RS00885	COG1674	ftsk spoiiie
L1879_RS00895	COG0740	serine-type endopeptidase activity
L1879_RS00900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L1879_RS00910	COG0527	aspartate kinase activity
L1879_RS00915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L1879_RS00920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L1879_RS00925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L1879_RS00930	COG1873	PFAM PRC-barrel domain
L1879_RS00935	COG0612	Peptidase, M16
L1879_RS00940	COG0726	polysaccharide deacetylase
L1879_RS00945	COG1185	polyribonucleotide nucleotidyltransferase activity
L1879_RS00950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
L1879_RS00955	COG0196	riboflavin kinase activity
L1879_RS00960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L1879_RS00965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L1879_RS00970	COG1550	Protein conserved in bacteria
L1879_RS00980	COG1358	cellular component organization or biogenesis
L1879_RS00985	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L1879_RS00990	COG0195	Participates in both transcription termination and antitermination
L1879_RS00995	COG0779	Required for maturation of 30S ribosomal subunits
L1879_RS01000	COG2176	DNA-directed DNA polymerase activity
L1879_RS01005	COG0442	prolyl-tRNA aminoacylation
L1879_RS01010	COG0750	zinc metalloprotease
L1879_RS01015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
L1879_RS01020	COG4589	Belongs to the CDS family
L1879_RS01025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L1879_RS01030	COG0233	cytoplasmic translational termination
L1879_RS01035	COG0528	UMP kinase activity
L1879_RS01040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
L1879_RS01045	COG0052	Belongs to the universal ribosomal protein uS2 family
L1879_RS01055	COG1191	sigma factor activity
L1879_RS01060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
L1879_RS01065	COG1776	CheC inhibitor of MCP methylation
L1879_RS01070	COG0835	chemotaxis
L1879_RS01075	COG2198	Histidine kinase
L1879_RS01075	COG0643	Histidine kinase
L1879_RS01080	COG2201	protein-glutamate methylesterase activity
L1879_RS01085	COG0455	bacterial-type flagellum organization
L1879_RS01090	COG1419	protein localization to endoplasmic reticulum
L1879_RS01095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L1879_RS01100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L1879_RS01105	COG1684	flagellar biosynthetic protein fliR
L1879_RS01110	COG1987	bacterial-type flagellum assembly
L1879_RS01115	COG1338	Plays a role in the flagellum-specific transport system
L1879_RS01120	COG3190	flagellar
L1879_RS01125	COG2201	protein-glutamate methylesterase activity
L1879_RS01130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L1879_RS01130	COG1776	CheC inhibitor of MCP methylation
L1879_RS01135	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L1879_RS01140	COG1580	Controls the rotational direction of flagella during chemotaxis
L1879_RS01150	COG4786	Flagellar basal body rod
L1879_RS01165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
L1879_RS01180	COG2882	bacterial-type flagellum organization
L1879_RS01185	COG1157	protein secretion by the type III secretion system
L1879_RS01190	COG1317	bacterial-type flagellum organization
L1879_RS01195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L1879_RS01200	COG1766	The M ring may be actively involved in energy transduction
L1879_RS01205	COG1677	Flagellar hook-basal body complex protein FliE
L1879_RS01210	COG1558	bacterial-type flagellum-dependent cell motility
L1879_RS01215	COG1815	bacterial-type flagellum-dependent cell motility
L1879_RS01220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L1879_RS01230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
L1879_RS01235	COG4974	Belongs to the 'phage' integrase family
L1879_RS01240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L1879_RS01245	COG0758	DNA mediated transformation
L1879_RS01250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L1879_RS01255	COG0045	succinate-CoA ligase (ADP-forming) activity
L1879_RS01260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L1879_RS01275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L1879_RS01290	COG0336	Belongs to the RNA methyltransferase TrmD family
L1879_RS01295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L1879_RS01305	COG1837	Belongs to the UPF0109 family
L1879_RS01315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L1879_RS01320	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
L1879_RS01325	COG0552	protein localization to endoplasmic reticulum
L1879_RS01330	COG1196	nuclear chromosome segregation
L1879_RS01335	COG0571	ribonuclease III activity
L1879_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS01350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L1879_RS01355	COG0416	fatty acid biosynthetic process
L1879_RS01360	COG1349	DNA-binding transcription factor activity
L1879_RS01365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L1879_RS01370	COG1760	l-serine dehydratase
L1879_RS01375	COG1760	l-serine dehydratase
L1879_RS01380	COG1461	Dihydroxyacetone kinase
L1879_RS01385	COG1302	Protein conserved in bacteria
L1879_RS01390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L1879_RS01400	COG1564	THIamine pyrophosphokinase
L1879_RS01405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L1879_RS01415	COG2815	serine threonine protein kinase
L1879_RS01415	COG0515	serine threonine protein kinase
L1879_RS01420	COG0631	protein serine/threonine phosphatase activity
L1879_RS01425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1879_RS01425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L1879_RS01430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L1879_RS01435	COG0242	peptide deformylase activity
L1879_RS01440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L1879_RS01445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L1879_RS01450	COG1758	RNA polymerase activity
L1879_RS01455	COG0194	GDP metabolic process
L1879_RS01460	COG2052	Domain of unknown function (DUF370)
L1879_RS01465	COG1561	YicC-like family, N-terminal region
L1879_RS01470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L1879_RS01480	COG0385	Bile acid
L1879_RS01495	COG2211	Major facilitator Superfamily
L1879_RS01505	COG0628	permease
L1879_RS01520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS01555	COG1309	transcriptional regulator
L1879_RS01560	COG0477	Major facilitator Superfamily
L1879_RS01565	COG0477	Major facilitator Superfamily
L1879_RS01570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L1879_RS01590	COG1803	Methylglyoxal synthase
L1879_RS01615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L1879_RS01620	COG0284	orotidine-5'-phosphate decarboxylase activity
L1879_RS01625	COG0167	dihydroorotate dehydrogenase activity
L1879_RS01630	COG0543	2 iron, 2 sulfur cluster binding
L1879_RS01645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L1879_RS01650	COG0540	Belongs to the ATCase OTCase family
L1879_RS01655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
L1879_RS01660	COG0564	pseudouridine synthase activity
L1879_RS01665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L1879_RS01680	COG3599	regulation of cell shape
L1879_RS01685	COG2302	S4 RNA-binding domain
L1879_RS01690	COG0762	integral membrane protein
L1879_RS01695	COG1799	cell septum assembly
L1879_RS01700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L1879_RS01710	COG1388	LysM domain
L1879_RS01710	COG3584	3D domain protein
L1879_RS01715	COG1873	PFAM PRC-barrel domain
L1879_RS01720	COG1191	sigma factor activity
L1879_RS01725	COG1191	sigma factor activity
L1879_RS01735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L1879_RS01740	COG0849	cell division
L1879_RS01745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L1879_RS01750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L1879_RS01755	COG0772	Belongs to the SEDS family
L1879_RS01760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L1879_RS01765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L1879_RS01780	COG0768	penicillin binding
L1879_RS01785	COG0768	penicillin binding
L1879_RS01790	COG4839	cell division protein FtsL
L1879_RS01795	COG0275	rRNA processing
L1879_RS01800	COG2001	Belongs to the MraZ family
L1879_RS01805	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
L1879_RS01810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L1879_RS01815	COG0454	-acetyltransferase
L1879_RS01825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L1879_RS01830	COG1399	metal-binding, possibly nucleic acid-binding protein
L1879_RS01835	COG1323	Belongs to the UPF0348 family
L1879_RS01840	COG3480	Lon protease (S16) C-terminal proteolytic domain
L1879_RS01845	COG1752	Esterase of the alpha-beta hydrolase superfamily
L1879_RS01850	COG3314	Sporulation integral membrane protein YlbJ
L1879_RS01855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
L1879_RS01860	COG0742	ribosomal rna small subunit methyltransferase
L1879_RS01870	COG4471	UPF0298 protein
L1879_RS01875	COG3679	Belongs to the UPF0342 family
L1879_RS01900	COG2340	Cysteine-rich secretory protein family
L1879_RS01915	COG3336	cytochrome c oxidase
L1879_RS01920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L1879_RS01940	COG0109	protoheme IX farnesyltransferase activity
L1879_RS01945	COG1612	heme a metabolic process
L1879_RS01950	COG0772	Belongs to the SEDS family
L1879_RS01955	COG4838	Belongs to the UPF0358 family
L1879_RS01960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L1879_RS01965	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L1879_RS01975	COG1217	gtp-binding protein TYPA
L1879_RS01985	COG0483	inositol monophosphate 1-phosphatase activity
L1879_RS02010	COG1982	Orn Lys Arg decarboxylase major
L1879_RS02050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L1879_RS02060	COG1473	amidohydrolase
L1879_RS02065	COG2171	N-acyltransferase activity
L1879_RS02070	COG0583	DNA-binding transcription factor activity
L1879_RS02075	COG0517	IMP dehydrogenase activity
L1879_RS02080	COG4703	Protein of unknown function (DUF1797)
L1879_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS02105	COG2409	Drug exporters of the RND superfamily
L1879_RS02105	COG1033	growth of symbiont in host cell
L1879_RS02115	COG0835	chemotaxis
L1879_RS02115	COG0784	Response regulator, receiver
L1879_RS02120	COG0436	Aminotransferase
L1879_RS02125	COG2084	Dehydrogenase
L1879_RS02140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1879_RS02160	COG3949	Membrane
L1879_RS02165	COG0542	response to heat
L1879_RS02180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L1879_RS02185	COG5002	protein histidine kinase activity
L1879_RS02200	COG0861	Integral membrane protein TerC family
L1879_RS02210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L1879_RS02215	COG3852	Histidine kinase
L1879_RS02220	COG0673	inositol 2-dehydrogenase activity
L1879_RS02225	COG0783	Belongs to the Dps family
L1879_RS02230	COG0730	response to heat
L1879_RS02240	COG1959	2 iron, 2 sulfur cluster binding
L1879_RS02260	COG0477	Major facilitator Superfamily
L1879_RS02285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L1879_RS02290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L1879_RS02315	COG1522	sequence-specific DNA binding
L1879_RS02320	COG2059	Chromate
L1879_RS02325	COG2059	Chromate
L1879_RS02370	COG3579	cysteine-type endopeptidase activity
L1879_RS02380	COG1668	transmembrane transport
L1879_RS02385	COG4152	abc transporter atp-binding protein
L1879_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS02395	COG1940	carbohydrate kinase activity
L1879_RS02415	COG2382	esterase
L1879_RS02425	COG2153	protein acetylation
L1879_RS02455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L1879_RS02490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L1879_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L1879_RS02500	COG0564	pseudouridine synthase activity
L1879_RS02510	COG2357	RelA SpoT domain protein
L1879_RS02525	COG0741	lytic transglycosylase activity
L1879_RS02530	COG2346	COG2346, Truncated hemoglobins
L1879_RS02535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L1879_RS02545	COG1164	Oligoendopeptidase f
L1879_RS02550	COG4469	Competence protein
L1879_RS02555	COG4862	establishment of competence for transformation
L1879_RS02560	COG1393	Belongs to the ArsC family
L1879_RS02565	COG4608	Belongs to the ABC transporter superfamily
L1879_RS02570	COG0444	Belongs to the ABC transporter superfamily
L1879_RS02575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1879_RS02580	COG0601	transmembrane transport
L1879_RS02585	COG4166	transmembrane transport
L1879_RS02595	COG0180	Tryptophanyl-tRNA synthetase
L1879_RS02605	COG0747	negative chemotaxis
L1879_RS02615	COG0601	transmembrane transport
L1879_RS02620	COG4608	Belongs to the ABC transporter superfamily
L1879_RS02635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L1879_RS02640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L1879_RS02670	COG2151	metal-sulfur cluster biosynthetic enzyme
L1879_RS02675	COG0561	phosphatase activity
L1879_RS02690	COG1307	EDD domain protein, DegV family
L1879_RS02710	COG0179	Fumarylacetoacetate (FAA) hydrolase
L1879_RS02715	COG2311	Membrane
L1879_RS02750	COG1074	ATP-dependent DNA helicase activity
L1879_RS02755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
L1879_RS02765	COG4903	ComK protein
L1879_RS02775	COG0501	Belongs to the peptidase M48B family
L1879_RS02785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L1879_RS02790	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS02795	COG0095	Lipoate-protein ligase
L1879_RS02810	COG1999	signal sequence binding
L1879_RS02820	COG0697	spore germination
L1879_RS02825	COG2814	Major facilitator Superfamily
L1879_RS02835	COG2190	(PTS) system
L1879_RS02835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1879_RS02835	COG1263	PTS System
L1879_RS02840	COG1511	domain protein
L1879_RS02845	COG1309	transcriptional regulator
L1879_RS02850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L1879_RS02855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L1879_RS02860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
L1879_RS02865	COG2329	Antibiotic biosynthesis monooxygenase
L1879_RS02870	COG3069	C4-dicarboxylate transmembrane transporter activity
L1879_RS02875	COG1473	amidohydrolase
L1879_RS02880	COG4473	ABC transporter
L1879_RS02885	COG1131	(ABC) transporter
L1879_RS02890	COG0537	adenosine 5'-monophosphoramidase activity
L1879_RS02910	COG1846	Transcriptional regulator
L1879_RS02925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L1879_RS02935	COG3481	metal-dependent phosphohydrolase, HD sub domain
L1879_RS02940	COG4717	serine-type aminopeptidase activity
L1879_RS02945	COG0420	3'-5' exonuclease activity
L1879_RS02950	COG3689	TIGRFAM TIGR03943 family protein
L1879_RS02955	COG0701	Predicted permease
L1879_RS02960	COG0861	Integral membrane protein TerC family
L1879_RS02970	COG1024	Enoyl-CoA hydratase
L1879_RS02980	COG0561	phosphatase activity
L1879_RS02990	COG4399	Belongs to the UPF0754 family
L1879_RS03000	COG0189	ligase activity
L1879_RS03005	COG0189	ligase activity
L1879_RS03015	COG2508	Transcriptional regulator
L1879_RS03020	COG3842	ATPase activity
L1879_RS03060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1879_RS03065	COG1481	regulation of sporulation
L1879_RS03070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L1879_RS03075	COG1660	Displays ATPase and GTPase activities
L1879_RS03080	COG1051	belongs to the nudix hydrolase family
L1879_RS03085	COG0492	ferredoxin-NADP+ reductase activity
L1879_RS03090	COG0457	Tetratricopeptide repeat
L1879_RS03095	COG0110	maltose O-acetyltransferase activity
L1879_RS03100	COG0546	phosphoglycolate phosphatase activity
L1879_RS03110	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
L1879_RS03120	COG3595	metallopeptidase activity
L1879_RS03125	COG0463	Glycosyl transferase, family 2
L1879_RS03125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
L1879_RS03130	COG1682	transport, permease protein
L1879_RS03145	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
L1879_RS03150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L1879_RS03155	COG0556	nucleotide-excision repair
L1879_RS03195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L1879_RS03210	COG0581	inorganic phosphate transmembrane transporter activity
L1879_RS03215	COG0573	inorganic phosphate transmembrane transporter activity
L1879_RS03225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L1879_RS03230	COG5002	protein histidine kinase activity
L1879_RS03235	COG0745	RESPONSE REGULATOR receiver
L1879_RS03255	COG4607	ABC-type enterochelin transport system periplasmic component
L1879_RS03260	COG4604	ABC transporter, ATP-binding protein
L1879_RS03265	COG4605	iron ion homeostasis
L1879_RS03270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1879_RS03275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L1879_RS03280	COG3409	Peptidoglycan-binding domain 1 protein
L1879_RS03280	COG0793	Belongs to the peptidase S41A family
L1879_RS03285	COG0460	homoserine dehydrogenase
L1879_RS03300	COG2873	o-acetylhomoserine
L1879_RS03310	COG0739	heme binding
L1879_RS03315	COG2177	Part of the ABC transporter FtsEX involved in
L1879_RS03320	COG2884	Cell division ATP-binding protein ftsE
L1879_RS03330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1879_RS03340	COG0653	protein targeting
L1879_RS03345	COG0405	Gamma-glutamyltransferase
L1879_RS03360	COG1516	flagellar protein fliS
L1879_RS03365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L1879_RS03370	COG1334	flagellar protein FlaG
L1879_RS03380	COG2094	Belongs to the DNA glycosylase MPG family
L1879_RS03390	COG1067	ATP-dependent peptidase activity
L1879_RS03405	COG1067	ATP-dependent peptidase activity
L1879_RS03415	COG0457	Tetratricopeptide repeat
L1879_RS03415	COG0463	Glycosyl transferase, family 2
L1879_RS03420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1879_RS03425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
L1879_RS03435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L1879_RS03440	COG1256	bacterial-type flagellum assembly
L1879_RS03440	COG4786	Flagellar basal body rod
L1879_RS03450	COG2747	anti-sigma28 factor FlgM
L1879_RS03460	COG1040	competence protein
L1879_RS03465	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L1879_RS03470	COG1307	EDD domain protein, DegV family
L1879_RS03475	COG0531	amino acid
L1879_RS03480	COG2197	response regulator
L1879_RS03490	COG1739	Uncharacterized protein family UPF0029
L1879_RS03495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L1879_RS03500	COG0768	penicillin binding
L1879_RS03520	COG1388	LysM domain
L1879_RS03520	COG0791	NLP P60 protein
L1879_RS03525	COG2188	Transcriptional regulator
L1879_RS03535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L1879_RS03540	COG0477	Major facilitator Superfamily
L1879_RS03550	COG1482	cell wall glycoprotein biosynthetic process
L1879_RS03555	COG0346	lactoylglutathione lyase activity
L1879_RS03560	COG2996	Protein conserved in bacteria
L1879_RS03580	COG1609	Transcriptional regulator
L1879_RS03585	COG2017	converts alpha-aldose to the beta-anomer
L1879_RS03590	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L1879_RS03595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1879_RS03610	COG1960	acyl-CoA dehydrogenase activity
L1879_RS03625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L1879_RS03630	COG1033	growth of symbiont in host cell
L1879_RS03630	COG2409	Drug exporters of the RND superfamily
L1879_RS03650	COG1113	amino acid transport
L1879_RS03655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L1879_RS03690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L1879_RS03695	COG1090	epimerase
L1879_RS03710	COG2226	methyltransferase
L1879_RS03745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L1879_RS03755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L1879_RS03760	COG0436	Aminotransferase
L1879_RS03765	COG0789	Transcriptional regulator
L1879_RS03775	COG1664	Polymer-forming cytoskeletal
L1879_RS03780	COG0534	Mate efflux family protein
L1879_RS03785	COG1250	3-hydroxyacyl-CoA dehydrogenase
L1879_RS03800	COG0297	glycogen (starch) synthase activity
L1879_RS03805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L1879_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS03820	COG4717	serine-type aminopeptidase activity
L1879_RS03825	COG0420	3'-5' exonuclease activity
L1879_RS03835	COG0431	NADPH-dependent FMN reductase
L1879_RS03875	COG0561	phosphatase activity
L1879_RS03885	COG1609	Transcriptional regulator
L1879_RS03895	COG0535	radical SAM domain protein
L1879_RS03910	COG0589	response to stress
L1879_RS03920	COG2244	polysaccharide biosynthetic process
L1879_RS03925	COG2746	aminoglycoside 3-N-acetyltransferase activity
L1879_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS03935	COG1268	BioY protein
L1879_RS03940	COG0024	Methionine aminopeptidase
L1879_RS03945	COG0791	NLP P60 protein
L1879_RS03945	COG1388	LysM domain
L1879_RS03960	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS03960	COG1454	alcohol dehydrogenase
L1879_RS03975	COG4145	pantothenate transmembrane transporter activity
L1879_RS03985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L1879_RS03990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L1879_RS04000	COG0010	Belongs to the arginase family
L1879_RS04005	COG0460	homoserine dehydrogenase
L1879_RS04010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L1879_RS04015	COG0083	homoserine kinase activity
L1879_RS04020	COG1116	anion transmembrane transporter activity
L1879_RS04025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS04030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS04040	COG0154	amidase activity
L1879_RS04050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L1879_RS04055	COG2079	MmgE PrpD family protein
L1879_RS04070	COG3716	PTS system mannose fructose sorbose family IID component
L1879_RS04075	COG3715	PTS system
L1879_RS04085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1879_RS04085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1879_RS04090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L1879_RS04090	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L1879_RS04100	COG2706	6-phosphogluconolactonase activity
L1879_RS04105	COG0011	TIGRFAM Protein of
L1879_RS04115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L1879_RS04125	COG3584	3D domain protein
L1879_RS04125	COG1388	LysM domain
L1879_RS04145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L1879_RS04150	COG0463	Glycosyl transferase, family 2
L1879_RS04150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
L1879_RS04160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS04165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS04170	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS04180	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
L1879_RS04190	COG5002	protein histidine kinase activity
L1879_RS04200	COG1609	Transcriptional regulator
L1879_RS04210	COG1554	hydrolase, family 65, central catalytic
L1879_RS04215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1879_RS04220	COG2801	Transposase and inactivated derivatives
L1879_RS04225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L1879_RS04230	COG1316	TRANSCRIPTIONal
L1879_RS04235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1879_RS04245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L1879_RS04255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L1879_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS04280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L1879_RS04285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L1879_RS04290	COG0604	alcohol dehydrogenase
L1879_RS04305	COG2207	Transcriptional regulator
L1879_RS04310	COG1653	transport
L1879_RS04330	COG0626	cystathionine gamma-synthase activity
L1879_RS04335	COG0626	cystathionine gamma-synthase activity
L1879_RS04345	COG2877	3-deoxy-8-phosphooctulonate synthase activity
L1879_RS04400	COG2186	Transcriptional regulator
L1879_RS04405	COG1620	l-lactate permease
L1879_RS04415	COG0531	amino acid
L1879_RS04435	COG2972	Histidine kinase
L1879_RS04485	COG1363	Peptidase, m42
L1879_RS04490	COG0737	Belongs to the 5'-nucleotidase family
L1879_RS04495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1879_RS04525	COG0584	glycerophosphoryl diester phosphodiesterase
L1879_RS04540	COG3290	protein histidine kinase activity
L1879_RS04540	COG3829	transcription factor binding
L1879_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS04555	COG2610	gluconate transmembrane transporter activity
L1879_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS04570	COG4720	Psort location CytoplasmicMembrane, score
L1879_RS04585	COG2116	formate transmembrane transporter activity
L1879_RS04600	COG1131	(ABC) transporter
L1879_RS04625	COG1104	cysteine desulfurase activity
L1879_RS04630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L1879_RS04635	COG0157	Belongs to the NadC ModD family
L1879_RS04645	COG0371	Dehydrogenase
L1879_RS04660	COG0606	chelatase, subunit chli
L1879_RS04670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1879_RS04680	COG4297	protein containing double-stranded beta helix domain
L1879_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS04695	COG0110	maltose O-acetyltransferase activity
L1879_RS04700	COG1510	regulation of RNA biosynthetic process
L1879_RS04705	COG0517	IMP dehydrogenase activity
L1879_RS04705	COG1125	glycine betaine transport
L1879_RS04710	COG1174	glycine betaine transport
L1879_RS04715	COG1732	Glycine betaine
L1879_RS04730	COG1609	Transcriptional regulator
L1879_RS04735	COG2814	Major facilitator Superfamily
L1879_RS04745	COG2814	Major facilitator Superfamily
L1879_RS04760	COG2211	Major facilitator Superfamily
L1879_RS04760	COG2190	(PTS) system
L1879_RS04765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1879_RS04775	COG1447	Phosphotransferase system cellobiose-specific component IIA
L1879_RS04780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1879_RS04785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1879_RS04785	COG3711	transcriptional antiterminator
L1879_RS04795	COG2130	NADP-dependent
L1879_RS04800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L1879_RS04830	COG4989	oxidoreductase activity
L1879_RS04840	COG1316	TRANSCRIPTIONal
L1879_RS04845	COG0531	amino acid
L1879_RS04865	COG2333	competence protein COMEC
L1879_RS04865	COG0658	competence protein
L1879_RS04875	COG2315	Protein conserved in bacteria
L1879_RS04905	COG5263	repeat protein
L1879_RS04905	COG0366	Alpha amylase catalytic
L1879_RS04915	COG2226	methyltransferase
L1879_RS04920	COG5504	Zn-dependent protease
L1879_RS04935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L1879_RS04940	COG4193	domain, Protein
L1879_RS04950	COG1063	alcohol dehydrogenase
L1879_RS04955	COG1940	carbohydrate kinase activity
L1879_RS04965	COG1070	Carbohydrate kinase
L1879_RS04975	COG1070	Carbohydrate kinase
L1879_RS04980	COG2115	Belongs to the xylose isomerase family
L1879_RS04990	COG1501	Belongs to the glycosyl hydrolase 31 family
L1879_RS05010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L1879_RS05020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L1879_RS05030	COG5039	Polysaccharide pyruvyl transferase
L1879_RS05035	COG1216	Glycosyl transferase, family 2
L1879_RS05045	COG0438	transferase activity, transferring glycosyl groups
L1879_RS05060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L1879_RS05065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L1879_RS05070	COG4464	protein tyrosine phosphatase activity
L1879_RS05075	COG0489	protein tyrosine kinase activity
L1879_RS05080	COG3944	biosynthesis protein
L1879_RS05105	COG0646	methionine synthase
L1879_RS05105	COG1410	methionine synthase
L1879_RS05110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L1879_RS05110	COG0646	methionine synthase
L1879_RS05130	COG0586	Pfam SNARE associated Golgi protein
L1879_RS05135	COG0586	Pfam SNARE associated Golgi protein
L1879_RS05145	COG1733	regulation of RNA biosynthetic process
L1879_RS05160	COG0765	amino acid transport
L1879_RS05165	COG0765	amino acid transport
L1879_RS05170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1879_RS05180	COG0628	permease
L1879_RS05185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L1879_RS05195	COG0531	amino acid
L1879_RS05205	COG0423	glycine-tRNA ligase activity
L1879_RS05220	COG1902	pentaerythritol trinitrate reductase activity
L1879_RS05230	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L1879_RS05235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L1879_RS05240	COG1301	dicarboxylic acid transport
L1879_RS05245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L1879_RS05250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L1879_RS05255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L1879_RS05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L1879_RS05270	COG3973	AAA domain
L1879_RS05275	COG0463	Glycosyl transferase, family 2
L1879_RS05280	COG2851	Citrate transporter
L1879_RS05285	COG4565	transcriptional regulatory protein
L1879_RS05290	COG3290	protein histidine kinase activity
L1879_RS05295	COG0004	ammonium transporteR
L1879_RS05300	COG1979	alcohol dehydrogenase
L1879_RS05305	COG0531	amino acid
L1879_RS05310	COG0247	lactate metabolic process
L1879_RS05315	COG1139	Iron-sulfur cluster binding protein
L1879_RS05320	COG1556	Lactate utilization protein
L1879_RS05325	COG0531	amino acid
L1879_RS05340	COG1177	transmembrane transport
L1879_RS05345	COG1176	ABC-type spermidine putrescine transport system, permease component I
L1879_RS05350	COG3842	ATPase activity
L1879_RS05360	COG0833	amino acid
L1879_RS05365	COG3104	oligopeptide transport
L1879_RS05370	COG1113	amino acid transport
L1879_RS05380	COG0667	Aldo Keto reductase
L1879_RS05385	COG5577	PFAM Coat F domain
L1879_RS05395	COG2848	UPF0210 protein
L1879_RS05410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L1879_RS05420	COG0702	epimerase
L1879_RS05435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L1879_RS05445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L1879_RS05465	COG0697	spore germination
L1879_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS05485	COG0371	Dehydrogenase
L1879_RS05495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L1879_RS05515	COG0175	sulfate reduction
L1879_RS05520	COG5434	Belongs to the glycosyl hydrolase 28 family
L1879_RS05530	COG0765	amino acid transport
L1879_RS05540	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS05545	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS05550	COG0217	transcriptional regulatory protein
L1879_RS05570	COG1120	ATPase activity
L1879_RS05575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L1879_RS05580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1879_RS05585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1879_RS05595	COG2076	Multidrug Resistance protein
L1879_RS05600	COG2076	Multidrug Resistance protein
L1879_RS05615	COG1215	transferase activity, transferring glycosyl groups
L1879_RS05620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
L1879_RS05625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1879_RS05635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1879_RS05645	COG2217	Heavy metal translocating P-type atpase
L1879_RS05655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L1879_RS05665	COG0716	FMN binding
L1879_RS05670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L1879_RS05680	COG1070	Carbohydrate kinase
L1879_RS05690	COG2188	Transcriptional regulator
L1879_RS05695	COG0366	Alpha amylase catalytic
L1879_RS05700	COG1263	PTS System
L1879_RS05700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1879_RS05705	COG2190	(PTS) system
L1879_RS05710	COG1174	glycine betaine transport
L1879_RS05715	COG1125	glycine betaine transport
L1879_RS05715	COG0517	IMP dehydrogenase activity
L1879_RS05735	COG0183	Belongs to the thiolase family
L1879_RS05740	COG3425	synthase
L1879_RS05755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L1879_RS05790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L1879_RS05805	COG0840	transmembrane signaling receptor activity
L1879_RS05810	COG1695	Transcriptional regulator
L1879_RS05825	COG0840	transmembrane signaling receptor activity
L1879_RS05830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L1879_RS05840	COG0583	DNA-binding transcription factor activity
L1879_RS05845	COG2814	Major facilitator Superfamily
L1879_RS05860	COG3335	DDE superfamily endonuclease
L1879_RS05870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L1879_RS05875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L1879_RS05880	COG4856	YbbR-like protein
L1879_RS05885	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L1879_RS05890	COG5662	AntiSigma factor
L1879_RS05895	COG1595	DNA-templated transcription, initiation
L1879_RS05970	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L1879_RS05975	COG4988	ABC transporter
L1879_RS05980	COG1294	oxidase, subunit
L1879_RS05985	COG1271	oxidase subunit
L1879_RS05995	COG0726	polysaccharide deacetylase
L1879_RS06010	COG2194	sulfuric ester hydrolase activity
L1879_RS06020	COG0489	protein tyrosine kinase activity
L1879_RS06025	COG0860	N-Acetylmuramoyl-L-alanine amidase
L1879_RS06035	COG0833	amino acid
L1879_RS06040	COG0529	Catalyzes the synthesis of activated sulfate
L1879_RS06045	COG2046	Belongs to the sulfate adenylyltransferase family
L1879_RS06055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L1879_RS06060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L1879_RS06070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L1879_RS06075	COG1122	ATPase activity
L1879_RS06080	COG1122	ATPase activity
L1879_RS06085	COG0203	ribosomal protein L17
L1879_RS06090	COG0202	RNA polymerase activity
L1879_RS06095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L1879_RS06100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L1879_RS06105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L1879_RS06110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L1879_RS06115	COG0563	adenylate kinase activity
L1879_RS06120	COG0201	protein transport
L1879_RS06125	COG0200	Binds to the 23S rRNA
L1879_RS06135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L1879_RS06140	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
L1879_RS06145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
L1879_RS06150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
L1879_RS06155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
L1879_RS06160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
L1879_RS06170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
L1879_RS06180	COG0255	Belongs to the universal ribosomal protein uL29 family
L1879_RS06185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
L1879_RS06190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
L1879_RS06200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L1879_RS06205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
L1879_RS06225	COG0051	transcription antitermination factor activity, RNA binding
L1879_RS06230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
L1879_RS06235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
L1879_RS06240	COG0049	tRNA binding
L1879_RS06245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L1879_RS06250	COG1358	cellular component organization or biogenesis
L1879_RS06260	COG0085	RNA polymerase activity
L1879_RS06265	COG2813	Specifically methylates the guanine in position
L1879_RS06275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
L1879_RS06280	COG0081	regulation of translation
L1879_RS06285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L1879_RS06290	COG0250	Participates in transcription elongation, termination and antitermination
L1879_RS06295	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L1879_RS06300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1879_RS06310	COG3688	RNA-binding protein containing a PIN domain
L1879_RS06315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L1879_RS06325	COG0215	cysteine-tRNA ligase activity
L1879_RS06330	COG1045	serine acetyltransferase
L1879_RS06335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L1879_RS06340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
L1879_RS06350	COG4956	integral membrane protein (PIN domain superfamily)
L1879_RS06355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L1879_RS06360	COG0542	response to heat
L1879_RS06365	COG3869	Catalyzes the specific phosphorylation of arginine residues in
L1879_RS06370	COG3880	PFAM UvrB UvrC protein
L1879_RS06425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L1879_RS06430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L1879_RS06435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L1879_RS06445	COG0590	tRNA wobble adenosine to inosine editing
L1879_RS06455	COG1388	LysM domain
L1879_RS06455	COG3858	chitin binding
L1879_RS06460	COG1428	Deoxynucleoside kinase
L1879_RS06465	COG1428	Deoxynucleoside kinase
L1879_RS06475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
L1879_RS06480	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
L1879_RS06495	COG0516	GMP reductase activity
L1879_RS06495	COG0517	IMP dehydrogenase activity
L1879_RS06585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L1879_RS06590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L1879_RS06595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L1879_RS06600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L1879_RS06605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L1879_RS06610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
L1879_RS06615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L1879_RS06620	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L1879_RS06625	COG0037	tRNA processing
L1879_RS06630	COG0515	serine threonine protein kinase
L1879_RS06635	COG2304	oxidoreductase activity
L1879_RS06640	COG2208	phosphoserine phosphatase activity
L1879_RS06650	COG1098	S1 RNA binding domain
L1879_RS06670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L1879_RS06680	COG2244	polysaccharide biosynthetic process
L1879_RS06685	COG2002	toxin-antitoxin pair type II binding
L1879_RS06690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L1879_RS06705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
L1879_RS06710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L1879_RS06715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
L1879_RS06750	COG0251	oxidation-reduction process
L1879_RS06755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L1879_RS06760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
L1879_RS06770	COG4466	Protein conserved in bacteria
L1879_RS06790	COG0084	hydrolase, TatD family'
L1879_RS06805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L1879_RS06810	COG2827	Endonuclease containing a URI domain
L1879_RS06815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L1879_RS06820	COG4467	Involved in initiation control of chromosome replication
L1879_RS06825	COG1774	PSP1 C-terminal conserved region
L1879_RS06830	COG0470	DNA polymerase III
L1879_RS06835	COG1728	Protein conserved in bacteria
L1879_RS06840	COG3870	Protein conserved in bacteria
L1879_RS06850	COG1982	Orn Lys Arg decarboxylase major
L1879_RS06885	COG3437	response regulator, receiver
L1879_RS06890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L1879_RS06895	COG0187	DNA topoisomerase II activity
L1879_RS06905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L1879_RS06910	COG2501	S4 domain
L1879_RS06915	COG0592	DNA-directed DNA polymerase activity
L1879_RS06920	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
L1879_RS06925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L1879_RS06930	COG0594	ribonuclease P activity
L1879_RS06935	COG0706	membrane insertase activity
L1879_RS06940	COG1847	R3H domain protein
L1879_RS06945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
L1879_RS06950	COG0445	tRNA wobble uridine modification
L1879_RS06955	COG0357	Ribosomal RNA small subunit methyltransferase G
L1879_RS06960	COG1475	DNA binding
L1879_RS06965	COG1192	Involved in chromosome partitioning
L1879_RS06970	COG1475	DNA binding
L1879_RS06975	COG1811	Na channel or pump
L1879_RS06985	COG0668	transmembrane transport
L1879_RS06990	COG4481	Protein conserved in bacteria
L1879_RS06995	COG0012	GTP binding
L1879_RS07000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L1879_RS07000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L1879_RS07005	COG0307	riboflavin synthase, alpha
L1879_RS07010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1879_RS07010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1879_RS07015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
L1879_RS07020	COG0360	Binds together with S18 to 16S ribosomal RNA
L1879_RS07030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L1879_RS07040	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L1879_RS07045	COG0359	binds to the 23S rRNA
L1879_RS07050	COG0305	Participates in initiation and elongation during chromosome replication
L1879_RS07055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L1879_RS07070	COG0745	RESPONSE REGULATOR receiver
L1879_RS07075	COG5002	protein histidine kinase activity
L1879_RS07080	COG4863	YycH protein
L1879_RS07085	COG4853	Protein conserved in bacteria
L1879_RS07090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L1879_RS07095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L1879_RS07100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
L1879_RS07110	COG0477	Major facilitator Superfamily
L1879_RS07115	COG0579	oxidoreductase
L1879_RS07120	COG0765	amino acid transport
L1879_RS07130	COG1126	abc transporter atp-binding protein
L1879_RS07140	COG3457	Alanine racemase
L1879_RS07160	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS07180	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
L1879_RS07190	COG1132	(ABC) transporter
L1879_RS07205	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
L1879_RS07210	COG0028	Belongs to the TPP enzyme family
L1879_RS07220	COG2814	Major facilitator Superfamily
L1879_RS07225	COG2195	Cleaves the N-terminal amino acid of tripeptides
L1879_RS07230	COG1442	glycosyl transferase family 8
L1879_RS07235	COG0534	Mate efflux family protein
L1879_RS07250	COG1119	ATPase activity
L1879_RS07255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L1879_RS07260	COG2011	ABC-type metal ion transport system permease component
L1879_RS07265	COG1464	Belongs to the NlpA lipoprotein family
L1879_RS07270	COG1966	Carbon starvation protein
L1879_RS07275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L1879_RS07280	COG2966	Psort location CytoplasmicMembrane, score
L1879_RS07295	COG0367	asparagine synthase
L1879_RS07300	COG0583	DNA-binding transcription factor activity
L1879_RS07310	COG1380	Effector of murein hydrolase LrgA
L1879_RS07315	COG1346	cytolysis
L1879_RS07325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L1879_RS07340	COG1737	Transcriptional regulator
L1879_RS07345	COG1785	Belongs to the alkaline phosphatase family
L1879_RS07350	COG0514	ATP-dependent DNA helicase (RecQ)
L1879_RS07355	COG0561	phosphatase activity
L1879_RS07370	COG0351	phosphomethylpyrimidine kinase
L1879_RS07380	COG1473	amidohydrolase
L1879_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
L1879_RS07395	COG3949	Membrane
L1879_RS07415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
L1879_RS07425	COG2363	Small membrane protein
L1879_RS07435	COG3253	May function as heme-dependent peroxidase
L1879_RS07445	COG0280	phosphate acetyltransferase
L1879_RS07455	COG0095	Lipoate-protein ligase
L1879_RS07465	COG1078	dGTPase activity
L1879_RS07470	COG3465	dGTPase activity
L1879_RS07480	COG1994	Peptidase M50
L1879_RS07490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1879_RS07495	COG0010	Belongs to the arginase family
L1879_RS07505	COG0018	arginyl-trna synthetase
L1879_RS07510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L1879_RS07515	COG0247	lactate metabolic process
L1879_RS07515	COG2181	nitrate reductase activity
L1879_RS07520	COG0183	Belongs to the thiolase family
L1879_RS07525	COG1960	acyl-CoA dehydrogenase activity
L1879_RS07530	COG1960	acyl-CoA dehydrogenase activity
L1879_RS07535	COG1309	transcriptional regulator
L1879_RS07540	COG1703	isobutyryl-CoA mutase activity
L1879_RS07540	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L1879_RS07540	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
L1879_RS07545	COG3343	RNA polymerase activity
L1879_RS07550	COG0504	CTP synthase activity
L1879_RS07555	COG1725	Transcriptional regulator
L1879_RS07560	COG1131	(ABC) transporter
L1879_RS07575	COG2204	response regulator
L1879_RS07580	COG0191	fructose-bisphosphate aldolase activity
L1879_RS07585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L1879_RS07590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L1879_RS07595	COG1494	fructose-1,6-bisphosphatase
L1879_RS07600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L1879_RS07605	COG0254	rRNA binding
L1879_RS07610	COG1435	thymidine kinase activity
L1879_RS07620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L1879_RS07635	COG0009	L-threonylcarbamoyladenylate synthase
L1879_RS07640	COG1971	Probably functions as a manganese efflux pump
L1879_RS07650	COG0840	transmembrane signaling receptor activity
L1879_RS07655	COG0698	ribose 5-phosphate isomerase
L1879_RS07660	COG4475	Protein of unknown function (DUF436)
L1879_RS07665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L1879_RS07670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
L1879_RS07680	COG0356	it plays a direct role in the translocation of protons across the membrane
L1879_RS07685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L1879_RS07695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L1879_RS07700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
L1879_RS07705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
L1879_RS07710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
L1879_RS07715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
L1879_RS07720	COG4836	Membrane
L1879_RS07730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L1879_RS07735	COG2385	sporulation resulting in formation of a cellular spore
L1879_RS07740	COG0739	heme binding
L1879_RS07745	COG1609	Transcriptional regulator
L1879_RS07750	COG1077	Cell shape determining protein MreB Mrl
L1879_RS07755	COG4786	Flagellar basal body rod
L1879_RS07760	COG4786	Flagellar basal body rod
L1879_RS07765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L1879_RS07775	COG0629	single-stranded DNA binding
L1879_RS07795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L1879_RS07810	COG1253	flavin adenine dinucleotide binding
L1879_RS07815	COG0789	Transcriptional regulator
L1879_RS07820	COG1253	flavin adenine dinucleotide binding
L1879_RS07830	COG1181	Belongs to the D-alanine--D-alanine ligase family
L1879_RS07835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L1879_RS07845	COG1554	hydrolase, family 65, central catalytic
L1879_RS07850	COG5521	maltodextrose utilization protein MalA
L1879_RS07855	COG3833	ABC-type maltose transport systems, permease component
L1879_RS07860	COG1175	transmembrane transport
L1879_RS07865	COG2182	Extracellular solute-binding protein
L1879_RS07875	COG0366	Alpha amylase catalytic
L1879_RS07880	COG1609	Transcriptional regulator
L1879_RS07885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L1879_RS07890	COG1280	lysine exporter protein (LysE YggA)
L1879_RS07895	COG0513	Belongs to the DEAD box helicase family
L1879_RS07900	COG0705	Rhomboid family
L1879_RS07905	COG0736	holo-[acyl-carrier-protein] synthase activity
L1879_RS07910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L1879_RS07920	COG0864	Transcriptional regulator
L1879_RS07925	COG2337	Toxic component of a toxin-antitoxin (TA) module
L1879_RS07940	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS07945	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS07950	COG2172	sigma factor antagonist activity
L1879_RS07955	COG2208	phosphoserine phosphatase activity
L1879_RS07960	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS07965	COG2172	sigma factor antagonist activity
L1879_RS07970	COG1191	sigma factor activity
L1879_RS07975	COG2208	phosphoserine phosphatase activity
L1879_RS07980	COG2183	response to ionizing radiation
L1879_RS07990	COG3091	SprT-like family
L1879_RS08075	COG0802	atpase or kinase
L1879_RS08080	COG1214	PFAM Peptidase M22, glycoprotease
L1879_RS08085	COG0456	acetyltransferase
L1879_RS08090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L1879_RS08095	COG0488	(ABC) transporter
L1879_RS08100	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
L1879_RS08105	COG0805	protein transport
L1879_RS08115	COG1266	CAAX protease self-immunity
L1879_RS08120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L1879_RS08125	COG0459	protein refolding
L1879_RS08130	COG2246	polysaccharide biosynthetic process
L1879_RS08135	COG0463	Glycosyl transferase, family 2
L1879_RS08145	COG4948	Mandelate Racemase Muconate Lactonizing
L1879_RS08150	COG1335	isochorismatase
L1879_RS08155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L1879_RS08160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L1879_RS08170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L1879_RS08170	COG0519	Catalyzes the synthesis of GMP from XMP
L1879_RS08190	COG1940	carbohydrate kinase activity
L1879_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS08240	COG2391	methyltransferase activity
L1879_RS08245	COG0425	Belongs to the sulfur carrier protein TusA family
L1879_RS08250	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L1879_RS08255	COG2910	NAD(P)H-binding
L1879_RS08265	COG1725	Transcriptional regulator
L1879_RS08270	COG1131	(ABC) transporter
L1879_RS08300	COG2356	endonuclease I
L1879_RS08305	COG0471	metal ion transport
L1879_RS08315	COG0842	Transport permease protein
L1879_RS08325	COG1131	(ABC) transporter
L1879_RS08330	COG4585	Histidine kinase
L1879_RS08335	COG2197	response regulator
L1879_RS08340	COG2814	Major facilitator Superfamily
L1879_RS08345	COG1132	(ABC) transporter
L1879_RS08355	COG2252	PERMEase
L1879_RS08360	COG3711	transcriptional antiterminator
L1879_RS08370	COG1301	dicarboxylic acid transport
L1879_RS08395	COG1263	PTS System
L1879_RS08395	COG2190	(PTS) system
L1879_RS08395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1879_RS08400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L1879_RS08405	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
L1879_RS08415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L1879_RS08420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L1879_RS08425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L1879_RS08435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L1879_RS08440	COG0047	phosphoribosylformylglycinamidine synthase activity
L1879_RS08445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L1879_RS08450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L1879_RS08455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
L1879_RS08460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L1879_RS08465	COG0138	bifunctional purine biosynthesis protein purh
L1879_RS08470	COG0151	Belongs to the GarS family
L1879_RS08485	COG1470	cell adhesion involved in biofilm formation
L1879_RS08490	COG4496	protein, YerC YecD
L1879_RS08495	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
L1879_RS08500	COG0210	DNA helicase
L1879_RS08510	COG4851	CamS sex pheromone cAM373 precursor
L1879_RS08515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L1879_RS08520	COG2224	Isocitrate lyase
L1879_RS08525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L1879_RS08530	COG0154	amidase activity
L1879_RS08535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L1879_RS08560	COG1597	lipid kinase activity
L1879_RS08565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L1879_RS08610	COG1064	alcohol dehydrogenase
L1879_RS08620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1879_RS08645	COG0326	Molecular chaperone. Has ATPase activity
L1879_RS08655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1879_RS08660	COG0765	amino acid transport
L1879_RS08665	COG1126	abc transporter atp-binding protein
L1879_RS08670	COG1764	response to oxidative stress
L1879_RS08675	COG2814	Major facilitator Superfamily
L1879_RS08680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L1879_RS08685	COG1984	allophanate hydrolase subunit 2
L1879_RS08690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
L1879_RS08705	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
L1879_RS08715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L1879_RS08725	COG2390	Transcriptional regulator
L1879_RS08735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L1879_RS08740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
L1879_RS08750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L1879_RS08755	COG0516	GMP reductase activity
L1879_RS08760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS08765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L1879_RS08770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS08780	COG0431	NADPH-dependent FMN reductase
L1879_RS08785	COG5583	Uncharacterized small protein (DUF2292)
L1879_RS08790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1879_RS08790	COG3153	acetyltransferase
L1879_RS08810	COG0791	NLP P60 protein
L1879_RS08810	COG1388	LysM domain
L1879_RS08820	COG1132	(ABC) transporter
L1879_RS08825	COG1132	(ABC) transporter
L1879_RS08830	COG3876	Protein conserved in bacteria
L1879_RS08840	COG1472	Belongs to the glycosyl hydrolase 3 family
L1879_RS08845	COG0697	spore germination
L1879_RS08855	COG1278	Cold shock
L1879_RS08860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L1879_RS08865	COG5002	protein histidine kinase activity
L1879_RS08875	COG1276	copper resistance
L1879_RS08875	COG2372	response to copper ion
L1879_RS08880	COG4549	nuclear export factor GLE1
L1879_RS08890	COG1609	Transcriptional regulator
L1879_RS08895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L1879_RS08900	COG1869	D-ribose catabolic process
L1879_RS08905	COG1129	ABC transporter
L1879_RS08910	COG1172	Belongs to the binding-protein-dependent transport system permease family
L1879_RS08915	COG1879	ABC-type sugar transport system periplasmic component
L1879_RS08925	COG1929	Belongs to the glycerate kinase type-1 family
L1879_RS08930	COG1063	alcohol dehydrogenase
L1879_RS08940	COG1328	CTP reductase activity
L1879_RS08975	COG3403	YqcI/YcgG family
L1879_RS08990	COG2190	(PTS) system
L1879_RS08995	COG0386	Belongs to the glutathione peroxidase family
L1879_RS09000	COG1280	lysine exporter protein (LysE YggA)
L1879_RS09025	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L1879_RS09030	COG1715	Restriction endonuclease
L1879_RS09035	COG1802	Transcriptional regulator
L1879_RS09040	COG2084	Dehydrogenase
L1879_RS09050	COG2610	gluconate transmembrane transporter activity
L1879_RS09075	COG0531	amino acid
L1879_RS09080	COG1914	H( )-stimulated, divalent metal cation uptake system
L1879_RS09085	COG1556	Lactate utilization protein
L1879_RS09090	COG1139	Iron-sulfur cluster binding protein
L1879_RS09095	COG0247	lactate metabolic process
L1879_RS09105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L1879_RS09110	COG1454	alcohol dehydrogenase
L1879_RS09120	COG1953	Uracil, thiamine, allantoin
L1879_RS09125	COG0493	'glutamate synthase
L1879_RS09140	COG2186	Transcriptional regulator
L1879_RS09195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
L1879_RS09200	COG2188	Transcriptional regulator
L1879_RS09215	COG0753	catalase activity
L1879_RS09240	COG3588	fructose-bisphosphate aldolase
L1879_RS09265	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L1879_RS09290	COG3829	transcription factor binding
L1879_RS09295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L1879_RS09325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
L1879_RS09330	COG0210	DNA helicase
L1879_RS09335	COG2233	PERMEase
L1879_RS09340	COG0730	response to heat
L1879_RS09345	COG1113	amino acid transport
L1879_RS09350	COG0778	Nitroreductase
L1879_RS09360	COG2376	Dihydroxyacetone kinase
L1879_RS09365	COG1461	Dihydroxyacetone kinase
L1879_RS09370	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
L1879_RS09375	COG0667	Aldo Keto reductase
L1879_RS09380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L1879_RS09385	COG2357	RelA SpoT domain protein
L1879_RS09400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
L1879_RS09405	COG2814	Major facilitator Superfamily
L1879_RS09420	COG0561	phosphatase activity
L1879_RS09430	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L1879_RS09440	COG1349	DNA-binding transcription factor activity
L1879_RS09445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1879_RS09445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1879_RS09445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1879_RS09460	COG0025	NhaP-type Na H and K H
L1879_RS09465	COG0166	Belongs to the GPI family
L1879_RS09470	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
L1879_RS09475	COG1304	FMN binding
L1879_RS09530	COG1518	maintenance of DNA repeat elements
L1879_RS09535	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
L1879_RS09545	COG3620	sequence-specific DNA binding
L1879_RS09560	COG0737	Belongs to the 5'-nucleotidase family
L1879_RS09565	COG1737	Transcriptional regulator
L1879_RS09570	COG4086	secreted protein
L1879_RS09610	COG0860	N-Acetylmuramoyl-L-alanine amidase
L1879_RS09615	COG0288	reversible hydration of carbon dioxide
L1879_RS09620	COG2226	methyltransferase
L1879_RS09625	COG1854	S-ribosylhomocysteine lyase activity
L1879_RS09630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L1879_RS09635	COG0626	cystathionine gamma-synthase activity
L1879_RS09640	COG1585	Membrane protein implicated in regulation of membrane protease activity
L1879_RS09645	COG2268	Band 7 protein
L1879_RS09650	COG1077	Cell shape determining protein MreB Mrl
L1879_RS09655	COG1607	acyl-coa hydrolase
L1879_RS09660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L1879_RS09670	COG3189	MarR family transcriptional regulator
L1879_RS09685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L1879_RS09690	COG1360	Flagellar Motor Protein
L1879_RS09695	COG0693	protein deglycase activity
L1879_RS09700	COG0024	Methionine aminopeptidase
L1879_RS09705	COG4840	Belongs to the UPF0435 family
L1879_RS09710	COG1295	ribonuclease BN
L1879_RS09715	COG0477	Major facilitator Superfamily
L1879_RS09720	COG0387	Pfam Sodium calcium exchanger
L1879_RS09740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L1879_RS09745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1879_RS09765	COG0024	Methionine aminopeptidase
L1879_RS09795	COG0798	PFAM Bile acid sodium symporter
L1879_RS09820	COG1846	Transcriptional regulator
L1879_RS09825	COG1132	(ABC) transporter
L1879_RS09850	COG0840	transmembrane signaling receptor activity
L1879_RS09855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L1879_RS09865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L1879_RS09870	COG1279	arginine transmembrane transporter activity
L1879_RS09875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L1879_RS09880	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
L1879_RS09905	COG2839	Protein conserved in bacteria
L1879_RS09910	COG1823	symporter activity
L1879_RS09925	COG3655	Transcriptional regulator
L1879_RS09930	COG3739	integral membrane protein
L1879_RS09960	COG1511	domain protein
L1879_RS09965	COG1309	transcriptional regulator
L1879_RS09970	COG2132	Multicopper oxidase
L1879_RS09975	COG0252	asparaginase activity
L1879_RS09980	COG3275	phosphorelay sensor kinase activity
L1879_RS09985	COG3279	Response regulator of the LytR AlgR family
L1879_RS09990	COG2223	nitrite transmembrane transporter activity
L1879_RS09995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L1879_RS10000	COG0670	Belongs to the BI1 family
L1879_RS10005	COG2124	cytochrome p450
L1879_RS10015	COG1366	Belongs to the anti-sigma-factor antagonist family
L1879_RS10020	COG1114	Component of the transport system for branched-chain amino acids
L1879_RS10025	COG0129	dihydroxy-acid dehydratase activity
L1879_RS10030	COG0028	Belongs to the TPP enzyme family
L1879_RS10035	COG0440	acetolactate synthase activity
L1879_RS10040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L1879_RS10045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L1879_RS10055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
L1879_RS10060	COG0066	3-isopropylmalate dehydratase activity
L1879_RS10065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L1879_RS10080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L1879_RS10085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L1879_RS10090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L1879_RS10095	COG0840	transmembrane signaling receptor activity
L1879_RS10100	COG0058	SHG alpha-glucan phosphorylase activity
L1879_RS10105	COG0577	efflux transmembrane transporter activity
L1879_RS10105	COG1136	(ABC) transporter
L1879_RS10155	COG0577	efflux transmembrane transporter activity
L1879_RS10165	COG0512	Glutamine amidotransferase of anthranilate synthase
L1879_RS10165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L1879_RS10170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L1879_RS10175	COG0134	indole-3-glycerol-phosphate synthase activity
L1879_RS10190	COG0159	tryptophan synthase activity
L1879_RS10205	COG2137	regulation of response to DNA damage stimulus
L1879_RS10215	COG1194	a g-specific adenine glycosylase
L1879_RS10220	COG1988	membrane-bound metal-dependent
L1879_RS10230	COG1131	(ABC) transporter
L1879_RS10245	COG0493	'glutamate synthase
L1879_RS10250	COG0067	glutamate synthase
L1879_RS10250	COG0069	glutamate synthase activity
L1879_RS10250	COG0070	glutamate synthase
L1879_RS10255	COG0583	DNA-binding transcription factor activity
L1879_RS10260	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS10275	COG3557	Belongs to the UPF0374 family
L1879_RS10280	COG1132	(ABC) transporter
L1879_RS10290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
L1879_RS10295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1879_RS10295	COG1263	PTS System
L1879_RS10300	COG1737	Transcriptional regulator
L1879_RS10305	COG4129	membrane
L1879_RS10320	COG2814	Major facilitator Superfamily
L1879_RS10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1879_RS10330	COG1116	anion transmembrane transporter activity
L1879_RS10335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS10340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS10345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L1879_RS10360	COG0735	belongs to the Fur family
L1879_RS10365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L1879_RS10370	COG0583	DNA-binding transcription factor activity
L1879_RS10375	COG0028	Belongs to the TPP enzyme family
L1879_RS10380	COG3527	Alpha-acetolactate decarboxylase
L1879_RS10490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L1879_RS10510	COG0436	Aminotransferase
L1879_RS10515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1879_RS10520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L1879_RS10525	COG2011	ABC-type metal ion transport system permease component
L1879_RS10530	COG1464	Belongs to the NlpA lipoprotein family
L1879_RS10575	COG1131	(ABC) transporter
L1879_RS10590	COG0431	NADPH-dependent FMN reductase
L1879_RS10595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L1879_RS10600	COG1882	Formate acetyltransferase
L1879_RS10605	COG2116	formate transmembrane transporter activity
L1879_RS10610	COG1126	abc transporter atp-binding protein
L1879_RS10615	COG0765	amino acid transport
L1879_RS10620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1879_RS10625	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
L1879_RS10635	COG2095	MarC family integral membrane protein
L1879_RS10650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L1879_RS10655	COG2766	serine protein kinase
L1879_RS10660	COG2718	Belongs to the UPF0229 family
L1879_RS10675	COG0306	phosphate transporter
L1879_RS10680	COG1392	Phosphate transport regulator
L1879_RS10705	COG3594	Acyltransferase
L1879_RS10710	COG2719	SpoVR family
L1879_RS10720	COG0598	Magnesium transport protein CorA
L1879_RS10725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L1879_RS10730	COG0601	transmembrane transport
L1879_RS10735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1879_RS10740	COG0444	Belongs to the ABC transporter superfamily
L1879_RS10745	COG4166	transmembrane transport
L1879_RS10750	COG0791	NLP P60 protein
L1879_RS10755	COG4608	Belongs to the ABC transporter superfamily
L1879_RS10770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1879_RS10785	COG3383	formate dehydrogenase (NAD+) activity
L1879_RS10805	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L1879_RS10825	COG0126	phosphoglycerate kinase activity
L1879_RS10835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L1879_RS10840	COG0148	phosphopyruvate hydratase activity
L1879_RS10845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L1879_RS10855	COG0557	exoribonuclease II activity
L1879_RS10860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
L1879_RS10880	COG0488	(ABC) transporter
L1879_RS10900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L1879_RS10905	COG1595	DNA-templated transcription, initiation
L1879_RS10920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L1879_RS10930	COG0671	phosphoesterase, PA-phosphatase related
L1879_RS10935	COG0753	catalase activity
L1879_RS10945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L1879_RS10960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1879_RS10965	COG0772	Belongs to the SEDS family
L1879_RS10970	COG5577	PFAM Coat F domain
L1879_RS10985	COG1024	Enoyl-CoA hydratase
L1879_RS10985	COG1250	3-hydroxyacyl-CoA dehydrogenase
L1879_RS10990	COG0183	Belongs to the thiolase family
L1879_RS10995	COG1960	acyl-CoA dehydrogenase activity
L1879_RS11000	COG1393	Belongs to the ArsC family
L1879_RS11005	COG0509	glycine decarboxylation via glycine cleavage system
L1879_RS11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1879_RS11020	COG0396	ATPase activity
L1879_RS11025	COG0719	Fe-S assembly protein
L1879_RS11030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L1879_RS11035	COG0822	iron-sulfur transferase activity
L1879_RS11040	COG0719	Fe-S assembly protein
L1879_RS11045	COG0737	Belongs to the 5'-nucleotidase family
L1879_RS11050	COG3377	Domain of unknown function (DUF1805)
L1879_RS11060	COG0739	heme binding
L1879_RS11065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L1879_RS11070	COG4470	Protein conserved in bacteria
L1879_RS11075	COG2445	Protein of unknown function DUF86
L1879_RS11080	COG0647	UMP catabolic process
L1879_RS11085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L1879_RS11090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L1879_RS11095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L1879_RS11100	COG4837	Protein of unknown function (DUF1462)
L1879_RS11105	COG0316	Belongs to the HesB IscA family
L1879_RS11120	COG0492	ferredoxin-NADP+ reductase activity
L1879_RS11125	COG1252	NADH dehydrogenase
L1879_RS11135	COG3584	3D domain protein
L1879_RS11140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L1879_RS11150	COG0697	spore germination
L1879_RS11160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L1879_RS11175	COG2050	protein possibly involved in aromatic compounds catabolism
L1879_RS11180	COG2814	Major facilitator Superfamily
L1879_RS11190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L1879_RS11210	COG0656	L-ascorbic acid biosynthetic process
L1879_RS11215	COG1902	pentaerythritol trinitrate reductase activity
L1879_RS11225	COG1098	S1 RNA binding domain
L1879_RS11235	COG2155	Conserved Protein
L1879_RS11245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L1879_RS11265	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS11280	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L1879_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS11300	COG0840	transmembrane signaling receptor activity
L1879_RS11310	COG2190	(PTS) system
L1879_RS11315	COG1525	nuclease
L1879_RS11320	COG1937	Protein conserved in bacteria
L1879_RS11325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1879_RS11335	COG0038	chloride channel
L1879_RS11350	COG0726	polysaccharide deacetylase
L1879_RS11365	COG1388	LysM domain
L1879_RS11370	COG0745	RESPONSE REGULATOR receiver
L1879_RS11375	COG5002	protein histidine kinase activity
L1879_RS11400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L1879_RS11420	COG1522	sequence-specific DNA binding
L1879_RS11425	COG1937	Protein conserved in bacteria
L1879_RS11460	COG2608	mercury ion transmembrane transporter activity
L1879_RS11465	COG2217	Heavy metal translocating P-type atpase
L1879_RS11480	COG1285	pathogenesis
L1879_RS11610	COG1575	Belongs to the MenA family. Type 1 subfamily
L1879_RS11615	COG1169	isochorismate synthase
L1879_RS11620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
L1879_RS11625	COG0596	Alpha beta hydrolase
L1879_RS11630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L1879_RS11635	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS11640	COG4948	Mandelate Racemase Muconate Lactonizing
L1879_RS11650	COG0803	Belongs to the bacterial solute-binding protein 9 family
L1879_RS11660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
L1879_RS11665	COG0783	Belongs to the Dps family
L1879_RS11680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS11685	COG1116	anion transmembrane transporter activity
L1879_RS11690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS11710	COG0655	NAD(P)H dehydrogenase (quinone) activity
L1879_RS11715	COG1506	peptidase
L1879_RS11730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
L1879_RS11735	COG0367	asparagine synthase
L1879_RS11740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L1879_RS11745	COG2267	carboxylic ester hydrolase activity
L1879_RS11755	COG0275	rRNA processing
L1879_RS11765	COG2814	Major facilitator Superfamily
L1879_RS11770	COG0495	leucyl-tRNA aminoacylation
L1879_RS11785	COG2244	polysaccharide biosynthetic process
L1879_RS11790	COG1349	DNA-binding transcription factor activity
L1879_RS11795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L1879_RS11820	COG0510	thiamine kinase activity
L1879_RS11830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L1879_RS11835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1879_RS11840	COG5584	Small secreted protein
L1879_RS11870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1879_RS11875	COG4848	Belongs to the UPF0354 family
L1879_RS11880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1879_RS11890	COG1674	ftsk spoiiie
L1879_RS11895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L1879_RS11905	COG4980	gas vesicle protein
L1879_RS11910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L1879_RS11910	COG1605	Chorismate mutase
L1879_RS11920	COG0123	including yeast histone deacetylase and acetoin utilization protein
L1879_RS11925	COG0517	IMP dehydrogenase activity
L1879_RS11930	COG0454	-acetyltransferase
L1879_RS11935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L1879_RS11945	COG4149	molybdate abc transporter
L1879_RS11950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L1879_RS11955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L1879_RS11970	COG0303	'Molybdopterin
L1879_RS11975	COG1763	Mo-molybdopterin cofactor biosynthetic process
L1879_RS11980	COG0314	molybdopterin synthase activity
L1879_RS11985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
L1879_RS11990	COG0315	cyclic pyranopterin monophosphate synthase activity
L1879_RS11995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L1879_RS12000	COG2427	Protein of unknown function (DUF1641)
L1879_RS12005	COG3383	formate dehydrogenase (NAD+) activity
L1879_RS12010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L1879_RS12020	COG3290	protein histidine kinase activity
L1879_RS12020	COG3829	transcription factor binding
L1879_RS12025	COG1012	belongs to the aldehyde dehydrogenase family
L1879_RS12030	COG0506	proline dehydrogenase activity
L1879_RS12035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
L1879_RS12040	COG2199	diguanylate cyclase activity
L1879_RS12040	COG2203	Gaf domain
L1879_RS12045	COG1956	GAF domain-containing protein
L1879_RS12050	COG1309	transcriptional regulator
L1879_RS12055	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
L1879_RS12060	COG1104	cysteine desulfurase activity
L1879_RS12065	COG0301	tRNA thio-modification
L1879_RS12075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L1879_RS12080	COG0616	signal peptide processing
L1879_RS12085	COG1714	RDD family
L1879_RS12095	COG3874	Sporulation protein YtfJ
L1879_RS12100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L1879_RS12105	COG0827	DNA restriction-modification system
L1879_RS12110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L1879_RS12120	COG0589	response to stress
L1879_RS12130	COG0006	proline dipeptidase activity
L1879_RS12135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L1879_RS12140	COG4109	DRTGG domain
L1879_RS12150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L1879_RS12165	COG0587	DNA-directed DNA polymerase activity
L1879_RS12170	COG0281	malic enzyme
L1879_RS12175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
L1879_RS12180	COG0825	malonyl-CoA metabolic process
L1879_RS12185	COG0205	6-phosphofructokinase activity
L1879_RS12195	COG0628	permease
L1879_RS12200	COG2707	UPF0756 membrane protein
L1879_RS12205	COG0372	Belongs to the citrate synthase family
L1879_RS12210	COG0538	isocitrate dehydrogenase activity
L1879_RS12215	COG0039	L-malate dehydrogenase activity
L1879_RS12220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1879_RS12220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1879_RS12225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L1879_RS12230	COG1971	Probably functions as a manganese efflux pump
L1879_RS12235	COG0237	dephospho-CoA kinase activity
L1879_RS12240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L1879_RS12250	COG1473	amidohydrolase
L1879_RS12255	COG0747	negative chemotaxis
L1879_RS12260	COG0601	transmembrane transport
L1879_RS12270	COG0444	Belongs to the ABC transporter superfamily
L1879_RS12275	COG4608	Belongs to the ABC transporter superfamily
L1879_RS12295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L1879_RS12300	COG3611	Membrane attachment protein
L1879_RS12305	COG1484	DNA-dependent DNA replication
L1879_RS12315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L1879_RS12325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
L1879_RS12335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
L1879_RS12360	COG0604	alcohol dehydrogenase
L1879_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS12360	COG3321	synthase
L1879_RS12365	COG0431	NADPH-dependent FMN reductase
L1879_RS12385	COG1695	Transcriptional regulator
L1879_RS12415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L1879_RS12420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
L1879_RS12425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1879_RS12425	COG0072	phenylalanine-tRNA ligase activity
L1879_RS12435	COG0789	Transcriptional regulator
L1879_RS12435	COG4978	Transcriptional regulator
L1879_RS12445	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
L1879_RS12450	COG1286	toxin biosynthetic process
L1879_RS12455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L1879_RS12455	COG1796	DNA polymerase
L1879_RS12460	COG1193	negative regulation of DNA recombination
L1879_RS12465	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS12470	COG1309	transcriptional regulator
L1879_RS12475	COG1024	Enoyl-CoA hydratase
L1879_RS12480	COG2086	electron transfer activity
L1879_RS12485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L1879_RS12490	COG3118	belongs to the thioredoxin family
L1879_RS12495	COG0322	excinuclease ABC activity
L1879_RS12505	COG1719	4-vinyl reductase, 4VR
L1879_RS12510	COG2009	succinate dehydrogenase
L1879_RS12515	COG1053	succinate dehydrogenase
L1879_RS12520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L1879_RS12525	COG0824	Thioesterase
L1879_RS12530	COG2197	response regulator
L1879_RS12540	COG1846	Transcriptional regulator
L1879_RS12555	COG5577	PFAM Coat F domain
L1879_RS12560	COG1063	alcohol dehydrogenase
L1879_RS12565	COG5577	PFAM Coat F domain
L1879_RS12575	COG5401	PFAM Sporulation and spore germination
L1879_RS12580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L1879_RS12585	COG0622	Phosphoesterase
L1879_RS12605	COG1477	protein flavinylation
L1879_RS12605	COG0457	Tetratricopeptide repeat
L1879_RS12610	COG0544	peptidyl-prolyl cis-trans isomerase activity
L1879_RS12620	COG1067	ATP-dependent peptidase activity
L1879_RS12620	COG0470	DNA polymerase III
L1879_RS12625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L1879_RS12630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
L1879_RS12645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L1879_RS12650	COG0181	hydroxymethylbilane synthase activity
L1879_RS12660	COG0113	porphobilinogen synthase activity
L1879_RS12665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
L1879_RS12670	COG1388	LysM domain
L1879_RS12670	COG1388	LysM domain
L1879_RS12675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L1879_RS12685	COG0525	valine-tRNA ligase activity
L1879_RS12690	COG0285	dihydrofolate synthase activity
L1879_RS12725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1879_RS12735	COG1459	type II secretion system
L1879_RS12760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L1879_RS12770	COG2003	Belongs to the UPF0758 family
L1879_RS12775	COG1077	Cell shape determining protein MreB Mrl
L1879_RS12780	COG1792	Involved in formation and maintenance of cell shape
L1879_RS12790	COG0850	regulation of cytokinetic process
L1879_RS12795	COG2894	cell division
L1879_RS12805	COG1994	Peptidase M50
L1879_RS12810	COG1530	ribonuclease E activity
L1879_RS12815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L1879_RS12820	COG2868	ribosomal protein
L1879_RS12825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
L1879_RS12830	COG3290	protein histidine kinase activity
L1879_RS12835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
L1879_RS12840	COG4492	Belongs to the UPF0735 family
L1879_RS12845	COG0077	Prephenate dehydratase
L1879_RS12850	COG1827	regulation of RNA biosynthetic process
L1879_RS12865	COG0217	transcriptional regulatory protein
L1879_RS12870	COG0632	four-way junction helicase activity
L1879_RS12885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
L1879_RS12890	COG0343	queuine tRNA-ribosyltransferase activity
L1879_RS12895	COG1862	Preprotein translocase
L1879_RS12905	COG2323	membrane
L1879_RS12910	COG2244	polysaccharide biosynthetic process
L1879_RS12920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1879_RS12920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L1879_RS12925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L1879_RS12925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L1879_RS12930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L1879_RS12935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L1879_RS12940	COG1490	D-aminoacyl-tRNA deacylase activity
L1879_RS12945	COG1846	Transcriptional regulator
L1879_RS12950	COG1566	PFAM secretion protein HlyD family protein
L1879_RS12955	COG2814	Major facilitator Superfamily
L1879_RS12960	COG0860	N-Acetylmuramoyl-L-alanine amidase
L1879_RS12960	COG3103	Sh3 type 3 domain protein
L1879_RS12960	COG4991	sh3 domain protein
L1879_RS12970	COG0124	histidyl-tRNA synthetase
L1879_RS12975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
L1879_RS12985	COG0385	Bile acid
L1879_RS12990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L1879_RS12995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L1879_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS13005	COG1959	2 iron, 2 sulfur cluster binding
L1879_RS13010	COG1104	cysteine desulfurase activity
L1879_RS13015	COG0482	sulfurtransferase activity
L1879_RS13020	COG0457	Tetratricopeptide repeat
L1879_RS13020	COG1477	protein flavinylation
L1879_RS13025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L1879_RS13045	COG0628	permease
L1879_RS13050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L1879_RS13055	COG4472	Bacterial protein of unknown function (DUF965)
L1879_RS13060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L1879_RS13065	COG3906	Belongs to the UPF0473 family
L1879_RS13070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L1879_RS13075	COG4122	O-methyltransferase activity
L1879_RS13080	COG0572	uridine kinase
L1879_RS13085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L1879_RS13100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L1879_RS13115	COG0450	alkyl hydroperoxide reductase
L1879_RS13130	COG1183	phosphatidylcholine synthase activity
L1879_RS13160	COG1704	LemA family
L1879_RS13170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1879_RS13190	COG0446	pyridine nucleotide-disulphide oxidoreductase
L1879_RS13205	COG2210	Belongs to the sulfur carrier protein TusA family
L1879_RS13210	COG0071	Belongs to the small heat shock protein (HSP20) family
L1879_RS13220	COG3835	regulator
L1879_RS13225	COG0277	FAD linked oxidase domain protein
L1879_RS13230	COG0247	lactate metabolic process
L1879_RS13235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L1879_RS13240	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L1879_RS13250	COG1534	Rna-binding protein
L1879_RS13255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
L1879_RS13260	COG1713	HD superfamily hydrolase involved in NAD metabolism
L1879_RS13265	COG0799	negative regulation of ribosome biogenesis
L1879_RS13270	COG2226	methyltransferase
L1879_RS13275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L1879_RS13280	COG1596	polysaccharide export
L1879_RS13280	COG1555	photosystem II stabilization
L1879_RS13285	COG2131	deaminase
L1879_RS13290	COG2333	competence protein COMEC
L1879_RS13290	COG0658	competence protein
L1879_RS13300	COG1466	dna polymerase III delta subunit
L1879_RS13305	COG0268	Binds directly to 16S ribosomal RNA
L1879_RS13310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
L1879_RS13315	COG0860	N-Acetylmuramoyl-L-alanine amidase
L1879_RS13320	COG0481	GTPase activity
L1879_RS13325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L1879_RS13335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L1879_RS13340	COG0443	Heat shock 70 kDa protein
L1879_RS13350	COG2264	protein methyltransferase activity
L1879_RS13355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L1879_RS13360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L1879_RS13365	COG1283	sodium-dependent phosphate transmembrane transporter activity
L1879_RS13380	COG1610	YqeY-like protein
L1879_RS13395	COG1702	phosphate starvation-inducible protein PhoH
L1879_RS13400	COG1480	7TM receptor with intracellular HD hydrolase
L1879_RS13405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
L1879_RS13410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L1879_RS13415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L1879_RS13425	COG1381	Involved in DNA repair and RecF pathway recombination
L1879_RS13430	COG0517	IMP dehydrogenase activity
L1879_RS13440	COG0358	DNA primase activity
L1879_RS13445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L1879_RS13455	COG2010	Cytochrome c
L1879_RS13460	COG2384	SAM-dependent methyltransferase
L1879_RS13465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L1879_RS13470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
L1879_RS13480	COG0513	Belongs to the DEAD box helicase family
L1879_RS13485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
L1879_RS13490	COG3883	PFAM NLP P60 protein
L1879_RS13490	COG0791	NLP P60 protein
L1879_RS13500	COG1121	(ABC) transporter
L1879_RS13505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L1879_RS13510	COG0735	belongs to the Fur family
L1879_RS13515	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
L1879_RS13520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
L1879_RS13530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L1879_RS13535	COG0477	Major facilitator Superfamily
L1879_RS13540	COG0768	penicillin binding
L1879_RS13550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1879_RS13560	COG0705	Rhomboid family
L1879_RS13560	COG0457	Tetratricopeptide repeat
L1879_RS13565	COG4483	Protein conserved in bacteria
L1879_RS13570	COG1940	carbohydrate kinase activity
L1879_RS13580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L1879_RS13595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1879_RS13600	COG1459	type II secretion system
L1879_RS13605	COG4537	Required for transformation and DNA binding
L1879_RS13630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L1879_RS13645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L1879_RS13650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
L1879_RS13660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
L1879_RS13665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1879_RS13670	COG0095	Lipoate-protein ligase
L1879_RS13675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1879_RS13685	COG1752	Esterase of the alpha-beta hydrolase superfamily
L1879_RS13695	COG3872	metal-dependent enzyme
L1879_RS13705	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
L1879_RS13710	COG0006	proline dipeptidase activity
L1879_RS13715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
L1879_RS13720	COG3854	ATPases associated with a variety of cellular activities
L1879_RS13760	COG0511	ligase activity, forming carbon-carbon bonds
L1879_RS13765	COG0439	Biotin carboxylase
L1879_RS13770	COG1302	Protein conserved in bacteria
L1879_RS13780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L1879_RS13785	COG1570	exodeoxyribonuclease VII activity
L1879_RS13800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L1879_RS13805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L1879_RS13815	COG0497	DNA recombination
L1879_RS13820	COG0750	zinc metalloprotease
L1879_RS13825	COG0745	RESPONSE REGULATOR receiver
L1879_RS13830	COG0584	glycerophosphoryl diester phosphodiesterase
L1879_RS13845	COG3829	transcription factor binding
L1879_RS13845	COG3290	protein histidine kinase activity
L1879_RS13855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1879_RS13860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L1879_RS13865	COG0022	dehydrogenase e1 component
L1879_RS13870	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1879_RS13875	COG1105	Belongs to the carbohydrate kinase PfkB family
L1879_RS13890	COG1376	ErfK ybiS ycfS ynhG family protein
L1879_RS13900	COG2195	Cleaves the N-terminal amino acid of tripeptides
L1879_RS13915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L1879_RS13925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L1879_RS13930	COG0300	oxidoreductase activity
L1879_RS13935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L1879_RS13945	COG1388	LysM domain
L1879_RS13945	COG3858	chitin binding
L1879_RS13950	COG1073	alpha beta
L1879_RS13955	COG3853	Toxic anion resistance protein (TelA)
L1879_RS13960	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
L1879_RS13970	COG0667	Aldo Keto reductase
L1879_RS13985	COG1379	DNA repair
L1879_RS13990	COG1300	Membrane
L1879_RS13995	COG0735	belongs to the Fur family
L1879_RS14005	COG4974	Belongs to the 'phage' integrase family
L1879_RS14010	COG1686	Belongs to the peptidase S11 family
L1879_RS14025	COG1191	sigma factor activity
L1879_RS14045	COG0697	spore germination
L1879_RS14070	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L1879_RS14075	COG1686	Belongs to the peptidase S11 family
L1879_RS14080	COG2715	membrane protein required for spore maturation
L1879_RS14085	COG0700	Nucleoside recognition
L1879_RS14090	COG1187	pseudouridine synthase activity
L1879_RS14095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1879_RS14100	COG1333	cytochrome c biogenesis protein
L1879_RS14105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L1879_RS14110	COG0745	RESPONSE REGULATOR receiver
L1879_RS14115	COG5002	protein histidine kinase activity
L1879_RS14120	COG0739	heme binding
L1879_RS14120	COG0741	lytic transglycosylase activity
L1879_RS14120	COG1196	nuclear chromosome segregation
L1879_RS14125	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L1879_RS14130	COG1141	Ferredoxin
L1879_RS14140	COG0514	ATP-dependent DNA helicase (RecQ)
L1879_RS14145	COG1266	CAAX protease self-immunity
L1879_RS14160	COG3546	catalase activity
L1879_RS14175	COG1408	metallophosphoesterase
L1879_RS14185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L1879_RS14190	COG0492	ferredoxin-NADP+ reductase activity
L1879_RS14195	COG2339	peptidase activity
L1879_RS14200	COG3773	Cell wall hydrolase
L1879_RS14200	COG3409	Peptidoglycan-binding domain 1 protein
L1879_RS14205	COG2959	enzyme of heme biosynthesis
L1879_RS14210	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
L1879_RS14215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
L1879_RS14220	COG0539	negative regulation of cytoplasmic translation
L1879_RS14235	COG1160	GTP binding
L1879_RS14255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L1879_RS14260	COG0776	regulation of translation
L1879_RS14270	COG0142	geranyltranstransferase activity
L1879_RS14275	COG2226	methyltransferase
L1879_RS14280	COG0142	geranyltranstransferase activity
L1879_RS14285	COG0105	UTP biosynthetic process
L1879_RS14290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L1879_RS14295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
L1879_RS14300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
L1879_RS14305	COG4401	Chorismate mutase type I
L1879_RS14310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L1879_RS14315	COG0287	Prephenate dehydrogenase
L1879_RS14320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L1879_RS14325	COG0457	Tetratricopeptide repeat
L1879_RS14330	COG5582	Belongs to the UPF0302 family
L1879_RS14345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L1879_RS14355	COG4347	Protein of unknown function (DUF1405)
L1879_RS14365	COG2738	Putative neutral zinc metallopeptidase
L1879_RS14375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1879_RS14380	COG1694	Mazg nucleotide pyrophosphohydrolase
L1879_RS14385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
L1879_RS14390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L1879_RS14395	COG0438	transferase activity, transferring glycosyl groups
L1879_RS14415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
L1879_RS14420	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
L1879_RS14425	COG1199	ATP-dependent helicase activity
L1879_RS14425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L1879_RS14440	COG0017	Asparaginyl-tRNA synthetase
L1879_RS14445	COG3935	DnaD domain protein
L1879_RS14450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L1879_RS14455	COG4499	WXG100 protein secretion system (Wss), protein YukC
L1879_RS14455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1879_RS14460	COG3331	DNA recombination
L1879_RS14485	COG0071	Belongs to the small heat shock protein (HSP20) family
L1879_RS14490	COG1111	helicase
L1879_RS14490	COG1205	dead DEAH box helicase
L1879_RS14495	COG3359	exonuclease
L1879_RS14505	COG4474	Belongs to the UPF0398 family
L1879_RS14520	COG0116	Belongs to the methyltransferase superfamily
L1879_RS14525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L1879_RS14535	COG2233	PERMEase
L1879_RS14550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L1879_RS14555	COG0789	Transcriptional regulator
L1879_RS14560	COG0174	glutamine synthetase
L1879_RS14565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L1879_RS14575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L1879_RS14580	COG4224	UPF0291 protein
L1879_RS14595	COG3763	UPF0154 protein
L1879_RS14600	COG0785	Cytochrome C biogenesis protein
L1879_RS14605	COG2201	protein-glutamate methylesterase activity
L1879_RS14610	COG4846	Membrane protein involved in cytochrome C biogenesis
L1879_RS14620	COG0204	Acyl-transferase
L1879_RS14625	COG2027	D-alanyl-D-alanine carboxypeptidase
L1879_RS14630	COG1619	proteins homologs of microcin C7 resistance protein MccF
L1879_RS14660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
L1879_RS14665	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L1879_RS14670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
L1879_RS14675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L1879_RS14680	COG0505	Belongs to the CarA family
L1879_RS14685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
L1879_RS14690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
L1879_RS14695	COG0137	argininosuccinate synthase activity
L1879_RS14700	COG0165	Argininosuccinate lyase
L1879_RS14705	COG0436	Aminotransferase
L1879_RS14730	COG0789	Transcriptional regulator
L1879_RS14735	COG4990	cell redox homeostasis
L1879_RS14745	COG2404	hydrolase activity, acting on ester bonds
L1879_RS14750	COG1252	NADH dehydrogenase
L1879_RS14760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
L1879_RS14765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
L1879_RS14770	COG0701	Predicted permease
L1879_RS14785	COG0709	Synthesizes selenophosphate from selenide and ATP
L1879_RS14790	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
L1879_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS14810	COG2030	dehydratase
L1879_RS14820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L1879_RS14845	COG1131	(ABC) transporter
L1879_RS14850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L1879_RS14860	COG0783	Belongs to the Dps family
L1879_RS14865	COG1914	H( )-stimulated, divalent metal cation uptake system
L1879_RS14870	COG0494	nUDIX hydrolase
L1879_RS14875	COG1247	-acetyltransferase
L1879_RS14895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L1879_RS14900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L1879_RS14905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L1879_RS14910	COG0297	glycogen (starch) synthase activity
L1879_RS14920	COG0708	Exodeoxyribonuclease III
L1879_RS14925	COG3773	Cell wall hydrolase
L1879_RS14935	COG1028	Short-chain dehydrogenase reductase Sdr
L1879_RS14940	COG0039	L-malate dehydrogenase activity
L1879_RS14955	COG2322	membrane
L1879_RS14960	COG0561	phosphatase activity
L1879_RS14970	COG0318	PFAM AMP-dependent synthetase and ligase
L1879_RS14990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
L1879_RS15015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
L1879_RS15015	COG3264	Mechanosensitive ion channel
L1879_RS15020	COG3284	Transcriptional regulator
L1879_RS15025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1879_RS15030	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1879_RS15035	COG0022	dehydrogenase e1 component
L1879_RS15040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L1879_RS15045	COG0697	spore germination
L1879_RS15050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L1879_RS15055	COG0789	Transcriptional regulator
L1879_RS15065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L1879_RS15070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L1879_RS15075	COG2045	Belongs to the ComB family
L1879_RS15080	COG1809	phosphosulfolactate synthase activity
L1879_RS15090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1879_RS15095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L1879_RS15110	COG1846	Transcriptional regulator
L1879_RS15120	COG0747	negative chemotaxis
L1879_RS15125	COG0601	transmembrane transport
L1879_RS15130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1879_RS15135	COG0444	Belongs to the ABC transporter superfamily
L1879_RS15140	COG4608	Belongs to the ABC transporter superfamily
L1879_RS15145	COG1476	TRANSCRIPTIONal