locus-tag	class	description
HM987_RS00005	ENOG4105UYK	outer membrane protein a
HM987_RS00025	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HM987_RS00030	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HM987_RS00040	ENOG41080R2	UPF0102 protein
HM987_RS00050	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HM987_RS00055	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HM987_RS00060	ENOG4105DSJ	YicC domain protein
HM987_RS00075	ENOG4108PCN	EamA-like transporter family
HM987_RS00090	ENOG4105EEQ	Na H antiporter
HM987_RS00100	ENOG4105C28	cystathionine
HM987_RS00110	ENOG4107R37	Glutamate dehydrogenase
HM987_RS00120	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
HM987_RS00125	ENOG4107ENK	receptor
HM987_RS00135	ENOG410902V	Modulates RecA activity (By similarity)
HM987_RS00180	ENOG4105VMP	Transcriptional regulator
HM987_RS00190	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HM987_RS00195	ENOG4105C0B	DNA polymerase III (alpha subunit)
HM987_RS00205	ENOG4105D78	K07001 NTE family protein
HM987_RS00210	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HM987_RS00215	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HM987_RS00220	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HM987_RS00230	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HM987_RS00235	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HM987_RS00245	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HM987_RS00270	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HM987_RS00280	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HM987_RS00300	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HM987_RS00305	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HM987_RS00310	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HM987_RS00320	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HM987_RS00335	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HM987_RS00340	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HM987_RS00350	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HM987_RS00360	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HM987_RS00370	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HM987_RS00380	ENOG4107QP8	phosphohexose isomerase
HM987_RS00400	ENOG4105C37	(CBS) domain
HM987_RS00405	ENOG4108UUM	single-stranded DNA-binding protein
HM987_RS00410	ENOG4105CEN	a g-specific adenine glycosylase
HM987_RS00415	ENOG4105K70	DNA-binding protein
HM987_RS00420	ENOG4105C03	ribonuclease
HM987_RS00440	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HM987_RS00450	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
HM987_RS00490	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HM987_RS00505	ENOG4105VC4	domain protein
HM987_RS00510	ENOG4105BZU	Histidine kinase
HM987_RS00515	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HM987_RS00525	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HM987_RS00530	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HM987_RS00545	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HM987_RS00550	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HM987_RS00560	ENOG4107RJ9	Cell division protein FtsX
HM987_RS00565	ENOG4105C8T	Leucyl-tRNA synthetase
HM987_RS00585	ENOG4108MN8	Membrane
HM987_RS00595	ENOG4105CZH	peptidase
HM987_RS00600	ENOG4105CHM	Aminotransferase
HM987_RS00615	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HM987_RS00625	ENOG4105MJ2	Competence protein
HM987_RS00635	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HM987_RS00650	ENOG4105H3G	oxidoreductase
HM987_RS00660	ENOG4105CGK	Exodeoxyribonuclease III
HM987_RS00665	ENOG4105ER2	Ompa motb domain protein
HM987_RS00670	ENOG4105CPC	Aldo Keto reductase
HM987_RS00680	ENOG4108VVK	transcriptional Regulator, AsnC
HM987_RS00695	ENOG4105M08	Membrane
HM987_RS00700	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HM987_RS00715	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HM987_RS00720	ENOG4105CD3	dihydroorotase
HM987_RS00735	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HM987_RS00760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HM987_RS00765	ENOG4105BZU	Histidine kinase
HM987_RS00770	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HM987_RS00775	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HM987_RS00790	ENOG4105D1F	ATP-binding protein
HM987_RS00795	ENOG41083MR	nifu domain-containing protein
HM987_RS00800	ENOG4105CAY	ferredoxin--nadp reductase
HM987_RS00805	ENOG4108ZIT	Ferredoxin, 2FE-2S
HM987_RS00825	ENOG4105C02	permease
HM987_RS00830	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HM987_RS00835	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HM987_RS00840	ENOG4105K5M	30s ribosomal protein S16
HM987_RS00855	ENOG4105C0B	DNA polymerase III (alpha subunit)
HM987_RS00895	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HM987_RS00960	ENOG4105FFC	UPF0187 protein
HM987_RS00975	ENOG4107RY6	amino acid
HM987_RS01040	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HM987_RS01090	ENOG4105CB5	ATP-dependent DNA helicase recG
HM987_RS01140	ENOG4108UUM	single-stranded DNA-binding protein
HM987_RS01165	ENOG4105FA0	parb-like partition protein
HM987_RS01170	ENOG4105BZU	Histidine kinase
HM987_RS01180	ENOG4105SXS	Protein of unknown function (DUF456)
HM987_RS01220	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HM987_RS01235	ENOG4105CSA	Coproporphyrinogen iii oxidase
HM987_RS01255	ENOG4105MSB	protein, conserved in bacteria
HM987_RS01260	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HM987_RS01305	ENOG4105FDP	GntR family transcriptional regulator
HM987_RS01310	ENOG4105CMG	Carbohydrate kinase
HM987_RS01315	ENOG4105C93	Xylose Isomerase
HM987_RS01320	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HM987_RS01325	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HM987_RS01340	ENOG4105DMW	Dehydrogenase reductase
HM987_RS01345	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HM987_RS01350	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HM987_RS01355	ENOG4105D2H	Uronic isomerase
HM987_RS01365	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HM987_RS01370	ENOG4105EF1	ribulokinase
HM987_RS01380	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HM987_RS01385	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HM987_RS01390	ENOG4107RUZ	Sss sodium solute transporter superfamily
HM987_RS01415	ENOG4107SYN	Glycosyl hydrolases family 43
HM987_RS01440	ENOG4105CPC	Aldo Keto reductase
HM987_RS01455	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
HM987_RS01460	ENOG4108MYR	Secreted protein
HM987_RS01485	ENOG4105DT9	hydrolase family 43
HM987_RS01490	ENOG4105CT4	transporter
HM987_RS01495	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
HM987_RS01505	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
HM987_RS01530	ENOG4105C7Z	Conserved Protein
HM987_RS01550	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
HM987_RS01555	ENOG4105CG3	alpha amylase, catalytic region
HM987_RS01575	ENOG4105C27	TonB-dependent Receptor Plug
HM987_RS01580	ENOG4105ETE	Transcriptional regulator (LacI family
HM987_RS01590	ENOG4107URF	beta-phospho-glucomutase
HM987_RS01600	ENOG4108IUK	alpha amylase, catalytic
HM987_RS01605	ENOG4105CJQ	hydrolase, family 31
HM987_RS01610	ENOG4108IUM	Glycogen debranching enzyme
HM987_RS01620	ENOG4107T9C	Alpha amylase catalytic region
HM987_RS01645	ENOG4105CNG	UPF0061 protein
HM987_RS01665	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HM987_RS01685	ENOG4105CBX	hi0933 family
HM987_RS01690	ENOG4105BZU	Histidine kinase
HM987_RS01730	ENOG4105FE9	pseudouridine synthase
HM987_RS01745	ENOG410836F	Transposase
HM987_RS01760	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HM987_RS01770	ENOG4105E0R	Deoxyhypusine synthase
HM987_RS01775	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HM987_RS01800	ENOG4105CND	Glycosyl transferase, family 2
HM987_RS01805	ENOG4106WTF	Glycosyl transferase, family 2
HM987_RS01815	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HM987_RS01840	ENOG4105CKK	Glycosyl transferase, family 2
HM987_RS01855	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HM987_RS01860	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HM987_RS01885	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HM987_RS01900	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HM987_RS01915	ENOG4107Y2X	deaminase
HM987_RS01935	ENOG4105DWV	Homoserine O-trans-acetylase
HM987_RS01950	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HM987_RS01955	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HM987_RS01960	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HM987_RS01970	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HM987_RS01980	ENOG4108YZA	Nitrogen regulatory protein pii
HM987_RS02005	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HM987_RS02010	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HM987_RS02015	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HM987_RS02020	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HM987_RS02025	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HM987_RS02030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HM987_RS02035	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HM987_RS02040	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HM987_RS02045	ENOG4105CH7	arginosuccinase
HM987_RS02055	ENOG4107T6X	nag kinase
HM987_RS02065	ENOG4105C8Y	Acetylornithine aminotransferase
HM987_RS02075	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HM987_RS02080	ENOG4105CDH	Citrulline--aspartate ligase
HM987_RS02090	ENOG4105C26	Dehydrogenase
HM987_RS02095	ENOG4105C7B	Threonine dehydratase
HM987_RS02100	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HM987_RS02110	ENOG4105C7K	acetolactate synthase
HM987_RS02115	ENOG4105C01	Dihydroxy-acid dehydratase
HM987_RS02160	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HM987_RS02165	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HM987_RS02180	ENOG4105CBG	Sulfatase
HM987_RS02195	ENOG4107QNK	)-transporter
HM987_RS02250	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HM987_RS02275	ENOG4105C37	(CBS) domain
HM987_RS02290	ENOG4105VC4	domain protein
HM987_RS02305	ENOG4105DUX	Transporter
HM987_RS02310	ENOG4105DUX	Transporter
HM987_RS02320	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HM987_RS02325	ENOG4108QBX	(LipO)protein
HM987_RS02330	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS02335	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HM987_RS02340	ENOG4105CN1	protease
HM987_RS02345	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HM987_RS02350	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HM987_RS02360	ENOG4107YM1	mraZ protein
HM987_RS02365	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HM987_RS02375	ENOG4105CJN	penicillin-binding protein
HM987_RS02380	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HM987_RS02385	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HM987_RS02395	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HM987_RS02400	ENOG4105CNI	cell division protein FtsW
HM987_RS02405	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HM987_RS02410	ENOG4105DFU	Cell wall formation (By similarity)
HM987_RS02420	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HM987_RS02425	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HM987_RS02430	ENOG4105KTH	gatB Yqey
HM987_RS02450	ENOG4105EM2	membrane
HM987_RS02455	ENOG4105CBC	glutamate synthase
HM987_RS02505	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HM987_RS02510	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HM987_RS02520	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HM987_RS02525	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HM987_RS02530	ENOG4105C30	Nad-dependent epimerase dehydratase
HM987_RS02535	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HM987_RS02540	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HM987_RS02545	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HM987_RS02590	ENOG4108Z7G	MaoC domain protein dehydratase
HM987_RS02600	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HM987_RS02615	ENOG4105CG5	Glycosyl transferase (Group 1
HM987_RS02620	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HM987_RS02625	ENOG4105K64	Glycosyl transferase, family 2
HM987_RS02665	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HM987_RS02670	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HM987_RS02680	ENOG4105ESV	Glycosyl transferase, family 4
HM987_RS02695	ENOG41080XP	Cbs domain
HM987_RS02705	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HM987_RS02715	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HM987_RS02720	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HM987_RS02725	ENOG4105II7	pyrroline-5-carboxylate reductase
HM987_RS02730	ENOG4108PBI	Polysaccharide metabolism
HM987_RS02765	ENOG4105CB5	ATP-dependent DNA helicase recG
HM987_RS02775	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HM987_RS02780	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HM987_RS02785	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HM987_RS02790	ENOG4105EWM	Histidine kinase
HM987_RS02800	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HM987_RS02805	ENOG4105D2N	Aldolase
HM987_RS02815	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HM987_RS02825	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HM987_RS02830	ENOG4105C1A	potassium transporter peripheral membrane
HM987_RS02835	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HM987_RS02860	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HM987_RS02875	ENOG4107ZT5	Thiol disulfide interchange protein
HM987_RS02890	ENOG4105C26	Dehydrogenase
HM987_RS02900	ENOG4105NWN	ApaG protein
HM987_RS02905	ENOG4105DY8	decarboxylase
HM987_RS02915	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HM987_RS02920	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HM987_RS02925	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HM987_RS02930	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HM987_RS02960	ENOG4105DHF	Membrane
HM987_RS02970	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
HM987_RS02980	ENOG4105KME	endoribonuclease L-psp
HM987_RS03020	ENOG4105CJ2	(LipO)protein
HM987_RS03030	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HM987_RS03050	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HM987_RS03065	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HM987_RS03095	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HM987_RS03115	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
HM987_RS03120	ENOG4105CHR	reductase
HM987_RS03140	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HM987_RS03145	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HM987_RS03165	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HM987_RS03175	ENOG4105EGD	dinuclear metal center protein, YbgI family
HM987_RS03180	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HM987_RS03190	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HM987_RS03195	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HM987_RS03215	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HM987_RS03225	ENOG4105EMN	RNA polymerase sigma factor
HM987_RS03230	ENOG4107R0I	Cell wall formation (By similarity)
HM987_RS03245	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HM987_RS03250	ENOG4105CNI	cell division protein FtsW
HM987_RS03255	ENOG4105CJN	penicillin-binding protein
HM987_RS03270	ENOG4105DFF	Rod shape-determining protein mreb
HM987_RS03275	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HM987_RS03285	ENOG4107S85	alpha-2-macroglobulin domain protein
HM987_RS03295	ENOG4105DUM	transcriptional regulator, lysR family
HM987_RS03310	ENOG4108TWJ	NADH dehydrogenase subunit 5
HM987_RS03315	ENOG4105EVH	UPF0753 protein
HM987_RS03325	ENOG4108JJA	ABC, transporter
HM987_RS03340	ENOG4105DFU	Cell wall formation (By similarity)
HM987_RS03345	ENOG4107ZT5	Thiol disulfide interchange protein
HM987_RS03380	ENOG4105W5Q	DNA repair protein (RadC
HM987_RS03400	ENOG4105D1H	recombination factor protein RarA
HM987_RS03410	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HM987_RS03420	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HM987_RS03425	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HM987_RS03430	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HM987_RS03435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HM987_RS03440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HM987_RS03445	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HM987_RS03450	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HM987_RS03455	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HM987_RS03460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HM987_RS03465	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HM987_RS03470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HM987_RS03475	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HM987_RS03480	ENOG4105WNB	50s ribosomal protein l29
HM987_RS03485	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HM987_RS03490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HM987_RS03495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HM987_RS03500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HM987_RS03505	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HM987_RS03510	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HM987_RS03515	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HM987_RS03520	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HM987_RS03525	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HM987_RS03530	ENOG41084HK	50S ribosomal protein L30
HM987_RS03535	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HM987_RS03540	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HM987_RS03545	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HM987_RS03550	ENOG410864M	50S ribosomal protein L36
HM987_RS03555	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HM987_RS03560	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HM987_RS03565	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HM987_RS03570	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HM987_RS03575	ENOG4108ZT0	50S ribosomal protein l17
HM987_RS03580	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HM987_RS03585	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HM987_RS03615	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HM987_RS03620	ENOG4105KNE	Phosphatidate cytidylyltransferase
HM987_RS03630	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HM987_RS03635	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HM987_RS03650	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HM987_RS03655	ENOG41062IR	nudix hydrolase
HM987_RS03670	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HM987_RS03690	ENOG4105BZU	Histidine kinase
HM987_RS03695	ENOG4105EDV	vault protein
HM987_RS03700	ENOG4105C75	arginyL-tRNA synthetase
HM987_RS03715	ENOG4108YYS	metal-dependent hydrolase (By similarity)
HM987_RS03745	ENOG4105D7A	ATP-binding protein
HM987_RS03755	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
HM987_RS03765	ENOG4105FE9	pseudouridine synthase
HM987_RS03780	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HM987_RS03795	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HM987_RS03805	ENOG4105CAQ	asparagine synthetase
HM987_RS03810	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HM987_RS03815	ENOG4105BZU	Histidine kinase
HM987_RS03840	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HM987_RS03860	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HM987_RS03865	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HM987_RS03870	ENOG4105C8N	cysteinyl-tRNA synthetase
HM987_RS03875	ENOG4105EUJ	GTP cyclohydrolase i
HM987_RS03900	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HM987_RS03910	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
HM987_RS03955	ENOG4105BZU	Histidine kinase
HM987_RS03990	ENOG4108K8S	endonuclease I
HM987_RS04000	ENOG4107R5B	glutamine synthetase
HM987_RS04020	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HM987_RS04030	ENOG4105C2J	ABC transporter
HM987_RS04040	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HM987_RS04050	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HM987_RS04055	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HM987_RS04075	ENOG4105D5P	Methylmalonyl-coA mutase
HM987_RS04095	ENOG4108YXU	transcriptional regulator AsnC family
HM987_RS04105	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HM987_RS04115	ENOG4107XZQ	multidrug resistance protein
HM987_RS04130	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HM987_RS04140	ENOG4105CI3	gtp-binding protein typa
HM987_RS04160	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HM987_RS04170	ENOG4105CKK	Glycosyl transferase, family 2
HM987_RS04185	ENOG4105EGZ	biosynthesis protein
HM987_RS04205	ENOG4107XU6	Glycosyl transferase (Group 1
HM987_RS04235	ENOG4105CAK	Cell division ATP-binding protein ftsE
HM987_RS04240	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HM987_RS04245	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HM987_RS04250	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HM987_RS04255	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HM987_RS04260	ENOG4105DDQ	anthranilate synthase
HM987_RS04265	ENOG4105CRQ	synthase (Component I)
HM987_RS04275	ENOG410834F	Transcriptional regulator
HM987_RS04290	ENOG41085GJ	domain protein
HM987_RS04310	ENOG4105BZU	Histidine kinase
HM987_RS04315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HM987_RS04335	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HM987_RS04340	ENOG4107RBB	ABC transporter, permease
HM987_RS04350	ENOG4107RBB	ABC transporter, permease
HM987_RS04365	ENOG4105C19	ABC transporter
HM987_RS04395	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HM987_RS04400	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HM987_RS04405	ENOG4105E0X	reductase
HM987_RS04440	ENOG4105BZU	Histidine kinase
HM987_RS04445	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HM987_RS04450	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HM987_RS04455	ENOG4105E98	transcriptional regulator DeoR family
HM987_RS04460	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HM987_RS04465	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HM987_RS04470	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HM987_RS04505	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HM987_RS04535	ENOG4105DG6	mannose-6-phosphate isomerase
HM987_RS04570	ENOG4105F6J	Alpha beta hydrolase fold
HM987_RS04595	ENOG4105EMN	RNA polymerase sigma factor
HM987_RS04610	ENOG4105C1J	atp-dependent rna helicase
HM987_RS04615	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HM987_RS04635	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HM987_RS04655	ENOG4105FQP	Beta-lactamase
HM987_RS04670	ENOG4105FQP	Beta-lactamase
HM987_RS04680	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HM987_RS04690	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HM987_RS04825	ENOG4105X54	addiction module antidote protein
HM987_RS04850	ENOG41067XF	inhibitor
HM987_RS04870	ENOG4107RJ1	sodium solute
HM987_RS04890	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HM987_RS04920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HM987_RS04925	ENOG4105D3R	alkyl hydroperoxide reductase
HM987_RS04945	ENOG4107RZZ	dna polymerase iii epsilon subunit
HM987_RS04950	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HM987_RS04960	ENOG4105CEV	competence damage-inducible protein
HM987_RS04965	ENOG4105KDC	50s ribosomal protein l28
HM987_RS04970	ENOG41083ND	50S ribosomal protein L33
HM987_RS04980	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HM987_RS04985	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HM987_RS05005	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HM987_RS05015	ENOG4107ENK	receptor
HM987_RS05075	ENOG41074B2	UPF0747 protein
HM987_RS05115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HM987_RS05135	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HM987_RS05140	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HM987_RS05155	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HM987_RS05165	ENOG4105EA8	2-Nitropropane dioxygenase
HM987_RS05200	ENOG4107QI1	Mate efflux family protein
HM987_RS05225	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS05245	ENOG4105EMN	RNA polymerase sigma factor
HM987_RS05260	ENOG4105FQP	Beta-lactamase
HM987_RS05320	ENOG41082IR	Excinuclease ABC C subunit domain protein
HM987_RS05325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HM987_RS05340	ENOG4105C19	ABC transporter
HM987_RS05350	ENOG4105C5H	ABC transporter
HM987_RS05360	ENOG4105D75	Capsular exopolysaccharide family
HM987_RS05365	ENOG4105D3Q	Sugar transferase
HM987_RS05370	ENOG4107QQG	Dehydrogenase
HM987_RS05380	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HM987_RS05390	ENOG4105EY8	ABC transporter
HM987_RS05415	ENOG4105D2T	synthase
HM987_RS05425	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HM987_RS05430	ENOG4105F0R	Cytidylyltransferase
HM987_RS05505	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HM987_RS05510	ENOG4105CKW	Inner membrane protein yedI
HM987_RS05515	ENOG4108IUZ	ABC transporter
HM987_RS05520	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HM987_RS05525	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HM987_RS05530	ENOG4105C2X	Arabinose 5-phosphate isomerase
HM987_RS05535	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HM987_RS05545	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HM987_RS05600	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HM987_RS05610	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HM987_RS05620	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HM987_RS05650	ENOG4105C3F	Signal peptidase i
HM987_RS05655	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HM987_RS05665	ENOG4105FA0	parb-like partition protein
HM987_RS05670	ENOG4107QJE	Chromosome Partitioning Protein
HM987_RS05675	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HM987_RS05685	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HM987_RS05690	ENOG4105D5P	Methylmalonyl-coA mutase
HM987_RS05700	ENOG4105CMN	Methylmalonyl-coA mutase
HM987_RS05710	ENOG4105DBI	uridine monophosphokinase
HM987_RS05715	ENOG4107TJ9	Cytochrome
HM987_RS05730	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HM987_RS05735	ENOG4105EZV	Transcriptional regulator
HM987_RS05745	ENOG4105CPC	Aldo Keto reductase
HM987_RS05750	ENOG4107SET	aldo keto reductase
HM987_RS05770	ENOG4105ENX	hydrolase
HM987_RS05805	ENOG4105BZU	Histidine kinase
HM987_RS05915	ENOG4105C3M	thioredoxin reductase
HM987_RS05995	ENOG4105C5Q	Transcriptional regulator
HM987_RS06000	ENOG4108RMU	ferritin dps family protein
HM987_RS06015	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HM987_RS06045	ENOG4105EN6	Membrane
HM987_RS06085	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HM987_RS06150	ENOG4108HRK	Histidine kinase
HM987_RS06170	ENOG4105DY9	regulatoR
HM987_RS06185	ENOG4108AEY	RNA polymerase sigma factor
HM987_RS06190	ENOG4105CZH	peptidase
HM987_RS06235	ENOG4105D7N	magnesium and cobalt transport protein CorA
HM987_RS06250	ENOG4108Z03	MAF-like protein
HM987_RS06290	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HM987_RS06295	ENOG4105CRE	cytochrome C
HM987_RS06305	ENOG4105C28	cystathionine
HM987_RS06315	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HM987_RS06320	ENOG4107QWE	)-transporter
HM987_RS06325	ENOG4107W19	lmbE family
HM987_RS06335	ENOG4108Z7R	Chaperone CsaA
HM987_RS06345	ENOG4105BZ1	(ABC) transporter
HM987_RS06350	ENOG4107RDP	Dehydrogenase
HM987_RS06355	ENOG4107R6T	Involved in the transcription termination process (By similarity)
HM987_RS06365	ENOG4105VIE	preprotein translocase, subunit YajC
HM987_RS06370	ENOG4105C27	TonB-dependent Receptor Plug
HM987_RS06375	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HM987_RS06380	ENOG4105C98	muts2 protein
HM987_RS06385	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HM987_RS06390	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HM987_RS06400	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HM987_RS06420	ENOG4105CPP	Dehydrogenase, E1 component
HM987_RS06425	ENOG4105VN1	Heat shock protein
HM987_RS06445	ENOG4108JA2	transcriptioN-repair coupling factor
HM987_RS06455	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HM987_RS06460	ENOG4108U51	Universal stress protein
HM987_RS06465	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HM987_RS06510	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HM987_RS06515	ENOG4105K3M	)-transporter
HM987_RS06530	ENOG4108Z0Z	intracellular protease Pfpi family
HM987_RS06570	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HM987_RS06580	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HM987_RS06585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HM987_RS06605	ENOG4105C6E	dna polymerase iii
HM987_RS06620	ENOG4106H78	methyltransferase
HM987_RS06635	ENOG4105C7H	Helicase, RecD TraA family
HM987_RS06650	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HM987_RS06665	ENOG4107RJC	Iron-containing alcohol dehydrogenase
HM987_RS06685	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HM987_RS06700	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HM987_RS06705	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HM987_RS06710	ENOG4107U9T	Pfam:Ribonuclease_BN
HM987_RS06715	ENOG4105DY9	regulatoR
HM987_RS06720	ENOG4108HRK	Histidine kinase
HM987_RS06755	ENOG4105C25	Primosomal protein n'
HM987_RS06760	ENOG4108NEV	two component transcriptional regulator, LytTR family
HM987_RS06765	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
HM987_RS06770	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HM987_RS06775	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HM987_RS06780	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HM987_RS06795	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HM987_RS06800	ENOG4105CUT	histidyl-tRNA synthetase
HM987_RS06825	ENOG4105C8P	)-transporter
HM987_RS06850	ENOG4105EKX	Restriction modification system DNA (Specificity
HM987_RS06870	ENOG4105CB5	ATP-dependent DNA helicase recG
HM987_RS06895	ENOG4105CAQ	asparagine synthetase
HM987_RS06915	ENOG4105CA0	peroxidase
HM987_RS06985	ENOG4108UJU	UPF0301 protein
HM987_RS06990	ENOG4105K70	DNA-binding protein
HM987_RS06995	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HM987_RS07000	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HM987_RS07020	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HM987_RS07035	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HM987_RS07055	ENOG4108V06	Glutathione peroxidase
HM987_RS07060	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HM987_RS07070	ENOG4105EUJ	GTP cyclohydrolase i
HM987_RS07085	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HM987_RS07090	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HM987_RS07095	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HM987_RS07105	ENOG4105CGD	Nad-dependent epimerase dehydratase
HM987_RS07130	ENOG4105EE0	oxidoreductase
HM987_RS07175	ENOG4107R3N	Filamentation induced by cAMP protein fic
HM987_RS07265	ENOG4108I0Z	Aconitate hydratase
HM987_RS07280	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HM987_RS07295	ENOG4105EWK	phytoene
HM987_RS07315	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HM987_RS07320	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HM987_RS07330	ENOG4105VEJ	Heat shock protein
HM987_RS07345	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HM987_RS07350	ENOG4108HHA	Transketolase
HM987_RS07355	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HM987_RS07370	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HM987_RS07375	ENOG4105CDU	Replicative dna helicase
HM987_RS07380	ENOG4105DSF	transport protein
HM987_RS07385	ENOG4105F0I	Aminotransferase
HM987_RS07410	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HM987_RS07415	ENOG4108HCJ	Hydrolase
HM987_RS07420	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HM987_RS07425	ENOG4105VJV	50s ribosomal protein L35
HM987_RS07430	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HM987_RS07435	ENOG4105C22	threonyL-tRNA synthetase
HM987_RS07470	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HM987_RS07475	ENOG4105EJQ	L-serine dehydratase
HM987_RS07490	ENOG4105CFG	Acts as a chaperone (By similarity)
HM987_RS07495	ENOG4105C84	Histidine ammonia-lyase
HM987_RS07550	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HM987_RS07565	ENOG4105CAT	Cytidine monophosphate kinase
HM987_RS07575	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HM987_RS07580	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HM987_RS07585	ENOG4105CXT	aspartate transcarbamylase
HM987_RS07595	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HM987_RS07600	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HM987_RS07625	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HM987_RS07645	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HM987_RS07660	ENOG4105IIU	Aminopeptidase
HM987_RS07700	ENOG4105C59	p-type ATPase
HM987_RS07720	ENOG4105BZU	Histidine kinase
HM987_RS07725	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HM987_RS07745	ENOG4107YZX	Universal stress protein
HM987_RS07765	ENOG4105CY0	Metallo-Beta-Lactamase
HM987_RS07780	ENOG4107YZX	Universal stress protein
HM987_RS07800	ENOG41061HS	cysteine-type endopeptidase activity
HM987_RS07810	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HM987_RS07825	ENOG4105E9K	Isocitrate dehydrogenase
HM987_RS07835	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HM987_RS07840	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HM987_RS07845	ENOG4105DF9	Lipoate-protein, ligase
HM987_RS07850	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HM987_RS07865	ENOG4105DGW	oligopeptidase A
HM987_RS07870	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HM987_RS07875	ENOG4105P8F	nudix hydrolase
HM987_RS07895	ENOG4105CEP	NADH dehydrogenase
HM987_RS07910	ENOG41068WN	
HM987_RS07920	ENOG4105D6J	arsenicaL-resistance protein
HM987_RS07950	ENOG4105D98	threonine synthase
HM987_RS07960	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HM987_RS07965	ENOG4105CFH	Aspartokinase
HM987_RS07970	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HM987_RS07975	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HM987_RS07980	ENOG4105DR4	Methyltransferase
HM987_RS07985	ENOG4105EA8	2-Nitropropane dioxygenase
HM987_RS08035	ENOG4105KA0	thioesterase Superfamily protein
HM987_RS08040	ENOG4105E4F	Isochorismate synthase
HM987_RS08045	ENOG4107RE3	peptidase, S41
HM987_RS08050	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HM987_RS08060	ENOG4105QNR	S1 RNA binding domain protein
HM987_RS08075	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HM987_RS08080	ENOG4107W2A	UPF0173 metal-dependent hydrolase
HM987_RS08095	ENOG4105DTQ	mandelate racemase muconate lactonizing
HM987_RS08110	ENOG4105CP2	von willebrand factor, type a
HM987_RS08125	ENOG4105C3G	gtp-binding protein
HM987_RS08145	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
HM987_RS08155	ENOG4105DF5	DNA topoisomerase IV, subunit A
HM987_RS08165	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HM987_RS08170	ENOG4105EE5	Membrane protein terC
HM987_RS08190	ENOG4108VVK	transcriptional Regulator, AsnC
HM987_RS08200	ENOG4105D49	3-dehydroquinate synthase
HM987_RS08205	ENOG41062BK	proline dehydrogenase
HM987_RS08225	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HM987_RS08240	ENOG4105D3Q	Sugar transferase
HM987_RS08250	ENOG4105CAQ	asparagine synthetase
HM987_RS08255	ENOG4105CG5	Glycosyl transferase (Group 1
HM987_RS08270	ENOG4105K64	Glycosyl transferase, family 2
HM987_RS08280	ENOG4105CG5	Glycosyl transferase (Group 1
HM987_RS08290	ENOG4105K64	Glycosyl transferase, family 2
HM987_RS08295	ENOG4108J53	cell adhesion domain-containing protein
HM987_RS08305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HM987_RS08335	ENOG4105K8N	protein family UPF0079, ATPase
HM987_RS08340	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HM987_RS08345	ENOG4105DCI	Phosphohydrolase
HM987_RS08350	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS08355	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS08360	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS08365	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HM987_RS08370	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HM987_RS08380	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HM987_RS08390	ENOG4105CHR	reductase
HM987_RS08415	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HM987_RS08430	ENOG4108RMU	ferritin dps family protein
HM987_RS08465	ENOG4105CUY	Mechanosensitive ion channel
HM987_RS08470	ENOG4105VCH	membrane
HM987_RS08475	ENOG4105VEQ	Cold shock protein
HM987_RS08495	ENOG4108K5P	(LipO)protein
HM987_RS08515	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HM987_RS08535	ENOG4105C1J	atp-dependent rna helicase
HM987_RS08550	ENOG4105VEQ	Cold shock protein
HM987_RS08575	ENOG4105C26	Dehydrogenase
HM987_RS08580	ENOG4107GJV	short-chain dehydrogenase reductase
HM987_RS08590	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HM987_RS08650	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HM987_RS08665	ENOG4108RAV	Conserved protein
HM987_RS08675	ENOG4105NXH	GreA GreB family elongation factor
HM987_RS08680	ENOG4105D82	Glutamate dehydrogenase
HM987_RS08700	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HM987_RS08715	ENOG4108TYN	CAAX amino terminal protease family protein
HM987_RS08725	ENOG4108NEV	two component transcriptional regulator, LytTR family
HM987_RS08730	ENOG4108HRK	Histidine kinase
HM987_RS08745	ENOG4105DA5	(ABC) transporter
HM987_RS08750	ENOG4108HRK	Histidine kinase
HM987_RS08755	ENOG4105DY9	regulatoR
HM987_RS08760	ENOG4105CNT	hydrolase family 2
HM987_RS08770	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HM987_RS08780	ENOG4107S1E	Beta-lactamase
HM987_RS08790	ENOG4105DEN	Luciferase family
HM987_RS08795	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HM987_RS08800	ENOG4107RRE	RNA-directed DNA polymerase
HM987_RS08820	ENOG4105C1G	acyl-Coa dehydrogenase
HM987_RS08840	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HM987_RS08875	ENOG4105DY9	regulatoR
HM987_RS08890	ENOG4106210	phosphatase activity
HM987_RS08895	ENOG4105CSV	Glutaminase
HM987_RS08905	ENOG4105NPQ	Pfam:DUF403
HM987_RS08940	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HM987_RS08945	ENOG4105VDW	Csbd family
HM987_RS08955	ENOG4105CV6	ABC transporter, permease
HM987_RS08960	ENOG4108I0Y	(ABC) transporter
HM987_RS08965	ENOG4108UJV	acyl-CoA thioesterase i
HM987_RS08980	ENOG4105D64	Mechanosensitive ion channel
HM987_RS09055	ENOG4105D8V	Glucose sorbosone dehydrogenase
HM987_RS09075	ENOG4108R99	pseudouridine synthase
HM987_RS09085	ENOG4105KHC	sulfurtransferase
HM987_RS09100	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HM987_RS09110	ENOG4105YES	addiction module antidote protein
HM987_RS09120	ENOG4105CQB	FAD linked oxidase domain protein
HM987_RS09155	ENOG410606W	general stress protein
HM987_RS09170	ENOG4108QG2	Membrane
HM987_RS09175	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HM987_RS09185	ENOG4105KZX	Pterin carbinolamine dehydratase
HM987_RS09190	ENOG4105CDY	transcriptional regulatory protein
HM987_RS09200	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HM987_RS09365	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HM987_RS09485	ENOG4105CH2	amidohydrolase
HM987_RS09490	ENOG4105C28	cystathionine
HM987_RS09525	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HM987_RS09540	ENOG4105CNU	cell division protein FtsK
HM987_RS09555	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HM987_RS09600	ENOG4105UYK	outer membrane protein a
HM987_RS09650	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HM987_RS09655	ENOG4108RCM	Nitroreductase
HM987_RS09665	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HM987_RS09685	ENOG4107R7A	Allophanate hydrolase subunit 2
HM987_RS09690	ENOG4105P4J	Allophanate hydrolase, subunit 1
HM987_RS09695	ENOG4105E7W	lamb ycsf family protein
HM987_RS09725	ENOG4105C0P	Mg chelatase subunit ChlI
HM987_RS09755	ENOG4105DNZ	Alpha Beta Hydrolase
HM987_RS09760	ENOG4105CPN	adenine deaminase
HM987_RS09785	ENOG4105C1J	atp-dependent rna helicase
HM987_RS09815	ENOG4108HRK	Histidine kinase
HM987_RS09820	ENOG4105DY9	regulatoR
HM987_RS09830	ENOG4105RKW	reductase (By
HM987_RS09835	ENOG4107QN2	dihydrolipoyl dehydrogenase
HM987_RS09845	ENOG4105J0Q	Transcriptional regulator
HM987_RS09850	ENOG4105C28	cystathionine
HM987_RS09860	ENOG4105DFD	Na H antiporter
HM987_RS09865	ENOG4105D3R	alkyl hydroperoxide reductase
HM987_RS09870	ENOG41080RH	Thioredoxin
HM987_RS09880	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HM987_RS09895	ENOG4105C5H	ABC transporter
HM987_RS09905	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HM987_RS09915	ENOG4105E1F	short-chain dehydrogenase reductase
HM987_RS09950	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HM987_RS09960	ENOG4105D3G	Pseudouridine synthase
HM987_RS09985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HM987_RS09995	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HM987_RS10000	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HM987_RS10015	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HM987_RS10035	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
HM987_RS10040	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HM987_RS10045	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HM987_RS10050	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HM987_RS10065	ENOG4105DFA	alanine racemase domain protein
HM987_RS10070	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HM987_RS10080	ENOG4105EYW	Ion transport protein
HM987_RS10085	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HM987_RS10105	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HM987_RS10130	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HM987_RS10155	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HM987_RS10170	ENOG4105CGH	5'-nucleotidase
HM987_RS10180	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HM987_RS10185	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HM987_RS10190	ENOG4108MJ3	acetyltransferase
HM987_RS10200	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HM987_RS10210	ENOG4108TZV	Membrane
HM987_RS10220	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HM987_RS10230	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HM987_RS10235	ENOG4105KJF	protein tyrosine phosphatase
HM987_RS10245	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HM987_RS10260	ENOG4105HHA	aminodeoxychorismate lyase
HM987_RS10270	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HM987_RS10275	ENOG4105C0H	protease
HM987_RS10390	ENOG410836F	Transposase
HM987_RS10435	ENOG4105CVR	type I restriction-modification system
HM987_RS10495	ENOG4105D29	Helix-turn-helix type 11 domain protein
HM987_RS10505	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HM987_RS10515	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HM987_RS10520	ENOG4108JQ1	Dehydrogenase
HM987_RS10600	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HM987_RS10615	ENOG4107TDE	lipolytic protein G-D-S-L family
HM987_RS10620	ENOG4105C9Q	fumarate hydratase class II
HM987_RS10630	ENOG4105CI2	imidazolone-5-propionate hydrolase
HM987_RS10640	ENOG4105CYW	agmatinase
HM987_RS10680	ENOG4107VIJ	nudix hydrolase
HM987_RS10710	ENOG4105C5H	ABC transporter
HM987_RS10740	ENOG4107QX3	carboxylase
HM987_RS10780	ENOG4105CTQ	phosphohexokinase
HM987_RS10790	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HM987_RS10840	ENOG4107T0X	DNA ligase
HM987_RS10870	ENOG4105BZU	Histidine kinase
HM987_RS10875	ENOG4105BZU	Histidine kinase
HM987_RS10890	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HM987_RS10895	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HM987_RS10900	ENOG4105CHU	acetyl-coa acetyltransferase
HM987_RS10905	ENOG4107SN7	NLP P60 protein
HM987_RS10910	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
HM987_RS10930	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HM987_RS10935	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
HM987_RS10940	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HM987_RS10945	ENOG4105BZP	glycoside hydrolase 15-related
HM987_RS10950	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HM987_RS10960	ENOG4107QPH	glycogen) synthase
HM987_RS10965	ENOG4105E0X	reductase
HM987_RS10985	ENOG4107QN2	dihydrolipoyl dehydrogenase
HM987_RS10995	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HM987_RS11010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HM987_RS11030	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HM987_RS11065	ENOG4105C3J	Cysteine desulfurase
HM987_RS11095	ENOG4105C8Y	Acetylornithine aminotransferase
HM987_RS11110	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HM987_RS11130	ENOG4107QWK	SAICAR synthetase
HM987_RS11135	ENOG4105C9A	Phoh family
HM987_RS11165	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HM987_RS11190	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HM987_RS11195	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HM987_RS11205	ENOG4105K63	Thioredoxin
HM987_RS11265	ENOG4105DQE	DNA ligase
HM987_RS11270	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HM987_RS11290	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HM987_RS11325	ENOG4105C5I	Dehydrogenase
HM987_RS11340	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HM987_RS11345	ENOG4107ZT5	Thiol disulfide interchange protein
HM987_RS11365	ENOG4107QKV	phosphomannomutase
HM987_RS11405	ENOG4108ETH	Formylglycinamide ribotide synthetase
HM987_RS11420	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HM987_RS11430	ENOG4105CHU	acetyl-coa acetyltransferase
HM987_RS11440	ENOG4105C1G	acyl-Coa dehydrogenase
HM987_RS11475	ENOG4107VAM	peptidase, m28
HM987_RS11480	ENOG4105DR5	peptidase
HM987_RS11530	ENOG4105C59	p-type ATPase
HM987_RS11550	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HM987_RS11555	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HM987_RS11580	ENOG4108U51	Universal stress protein
HM987_RS11585	ENOG4105D4P	Coproporphyrinogen iii oxidase
HM987_RS11590	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HM987_RS11605	ENOG4108UT2	hemolysin iii
HM987_RS11615	ENOG4105CN9	Peptidase m42 family protein
HM987_RS11625	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
HM987_RS11635	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HM987_RS11640	ENOG4107QX3	carboxylase
HM987_RS11645	ENOG4105BZ1	(ABC) transporter
HM987_RS11655	ENOG4105C2C	drug resistance transporter, Bcr CflA
HM987_RS11660	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HM987_RS11680	ENOG4105C4R	Atp-dependent dna helicase
HM987_RS11695	ENOG4105CPK	Glycosyl transferase (Group 1
HM987_RS11700	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HM987_RS11705	ENOG4105EAC	phosphoserine phosphatase
HM987_RS11725	ENOG4105DF6	Fe-S oxidoreductase
HM987_RS11730	ENOG4105DF6	Fe-S oxidoreductase
HM987_RS11735	ENOG4107KIA	Virulence factor Mce family protein
HM987_RS11740	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HM987_RS11765	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HM987_RS11790	ENOG4105BZU	Histidine kinase
HM987_RS11800	ENOG4105K64	Glycosyl transferase, family 2
HM987_RS11810	ENOG4105CD3	dihydroorotase
HM987_RS11855	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HM987_RS11860	ENOG4105CSM	endonuclease III
HM987_RS11875	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HM987_RS11940	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HM987_RS11955	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HM987_RS11970	ENOG4105K89	arsenate reductase
HM987_RS11980	ENOG4107RNH	Outer membrane receptor FepA
HM987_RS11990	ENOG4105DQ4	alcohol dehydrogenase
HM987_RS12000	ENOG4107YBY	Hydrolase
HM987_RS12010	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HM987_RS12020	ENOG4105C26	Dehydrogenase
HM987_RS12030	ENOG4107QN1	sodium solute
HM987_RS12040	ENOG4105BZG	amino acid carrier protein
HM987_RS12080	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HM987_RS12105	ENOG4105E0A	ABC, transporter
HM987_RS12110	ENOG4105EHG	Permease protein
HM987_RS12140	ENOG4105T65	Membrane-associated protein
HM987_RS12155	ENOG4107QTF	adenylosuccinate lyase
HM987_RS12160	ENOG4105CGY	Dna recombination protein
HM987_RS12190	ENOG4105VG0	50S ribosomal protein l34
HM987_RS12200	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HM987_RS12225	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HM987_RS12245	ENOG41081WG	50s ribosomal protein l31
HM987_RS12255	ENOG4105CKK	Glycosyl transferase, family 2
HM987_RS12265	ENOG4105BZ1	(ABC) transporter
HM987_RS12270	ENOG4105DU6	RNA polymerase
HM987_RS12285	ENOG4105ERH	Fumarylacetoacetate hydrolase
HM987_RS12295	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HM987_RS12305	ENOG4108URH	decarboxylase
HM987_RS12320	ENOG4105CPP	Dehydrogenase, E1 component
HM987_RS12340	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HM987_RS12345	ENOG4108D32	Methyltransferase
HM987_RS12415	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HM987_RS12420	ENOG4105SFS	phosphoesterase RecJ domain protein
HM987_RS12430	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HM987_RS12435	ENOG4105CIN	aminoacyl-histidine dipeptidase
HM987_RS12440	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HM987_RS12470	ENOG4108RWN	rrna methyltransferase
HM987_RS12475	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HM987_RS12490	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HM987_RS12500	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HM987_RS12510	ENOG4105C8Y	Acetylornithine aminotransferase
HM987_RS12530	ENOG4105E2X	shikimate dehydrogenase
HM987_RS12555	ENOG4105DXN	mazG family
HM987_RS12565	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HM987_RS12570	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HM987_RS12575	ENOG41080ET	plasmid maintenance system killer protein
HM987_RS12580	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HM987_RS12585	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HM987_RS12610	ENOG4108SHN	Glycosyl transferase, family 2
HM987_RS12615	ENOG4106WTF	Glycosyl transferase, family 2
HM987_RS12620	ENOG4107BJW	polysaccharide deacetylase
HM987_RS12630	ENOG4106WTF	Glycosyl transferase, family 2
HM987_RS12635	ENOG4108TJN	glycosyl transferase group 1
HM987_RS12650	ENOG4105CAQ	asparagine synthetase
HM987_RS12665	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HM987_RS12680	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HM987_RS12695	ENOG4105CJ1	ABC, transporter
HM987_RS12765	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HM987_RS12775	ENOG4108SA1	esterase
HM987_RS12785	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HM987_RS12795	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HM987_RS12850	ENOG4105CSR	polyphosphate kinase 2
HM987_RS12865	ENOG4105EGS	Mechanosensitive ion channel
HM987_RS12870	ENOG4105RHA	ABC transporter, permease
HM987_RS12875	ENOG4108IUX	(ABC) transporter
HM987_RS12880	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HM987_RS12885	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HM987_RS12900	ENOG4105WH1	Two component transcriptional regulator luxr family
HM987_RS12905	ENOG4105BZU	Histidine kinase
HM987_RS12915	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HM987_RS12930	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HM987_RS12935	ENOG4105ECP	epimerase
HM987_RS13075	ENOG4108UB4	uncharacterized protein ygjQ
HM987_RS13095	ENOG4108W6C	Dehydrogenase
HM987_RS13120	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HM987_RS13125	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HM987_RS13135	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
HM987_RS13140	ENOG4105CNT	hydrolase family 2
HM987_RS13165	ENOG4107RT3	EamA-like transporter family
HM987_RS13180	ENOG4107UUY	ec 2.7.1.11
HM987_RS13190	ENOG4105ETE	Transcriptional regulator (LacI family
HM987_RS13200	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HM987_RS13205	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HM987_RS13210	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HM987_RS13215	ENOG4107VNI	ribosomal protein l10
HM987_RS13220	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HM987_RS13225	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HM987_RS13230	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HM987_RS13245	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HM987_RS13270	ENOG4105MS2	ribosomal subunit Interface protein
HM987_RS13275	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HM987_RS13280	ENOG4105C1G	acyl-Coa dehydrogenase
HM987_RS13290	ENOG4105BZG	amino acid carrier protein
HM987_RS13295	ENOG4107SVH	Potassium channel protein
HM987_RS13330	ENOG410900G	Protein of unknown function (DUF421)
HM987_RS13360	ENOG4107R34	abc transporter permease protein
HM987_RS13365	ENOG4105EHZ	conserved protein UCP016719
HM987_RS13375	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HM987_RS13395	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HM987_RS13405	ENOG4105EFZ	amidohydrolase
HM987_RS13420	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HM987_RS13455	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HM987_RS13465	ENOG4105C1J	atp-dependent rna helicase
HM987_RS13475	ENOG4105DWY	Agmatine deiminase
HM987_RS13540	ENOG4105BZU	Histidine kinase
HM987_RS13565	ENOG4105D1Q	UPF0246 protein
HM987_RS13570	ENOG4105C34	Pseudouridine synthase
HM987_RS13580	ENOG4105CPF	Cell wall formation (By similarity)
HM987_RS13585	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HM987_RS13635	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HM987_RS13670	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HM987_RS13690	ENOG4105CDV	Ompa motb domain protein
HM987_RS13700	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HM987_RS13705	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HM987_RS13715	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HM987_RS13725	ENOG4107RE3	peptidase, S41
HM987_RS13745	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HM987_RS13840	ENOG4105C5X	domain protein
HM987_RS13850	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HM987_RS13895	ENOG4105CP7	Triose-phosphate isomerase
HM987_RS13915	ENOG4105EEI	dihydropteroate synthase
HM987_RS13940	ENOG4105BZ1	(ABC) transporter
HM987_RS13945	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HM987_RS13960	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HM987_RS14005	ENOG4107QHF	type ii secretion system protein e
HM987_RS14010	ENOG4106855	Competence protein
HM987_RS14100	ENOG4108KEZ	Dehydrogenase
HM987_RS14105	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HM987_RS14115	ENOG4105D7K	pfkb domain protein
HM987_RS14135	ENOG4105C27	TonB-dependent Receptor Plug
HM987_RS14140	ENOG4108HKT	sucrose-6-phosphate hydrolase
HM987_RS14185	ENOG4105C5H	ABC transporter
HM987_RS14195	ENOG4108DNB	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HM987_RS14215	ENOG4105E6M	Sulphatase-modifying factor protein
HM987_RS14240	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HM987_RS14270	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HM987_RS14275	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HM987_RS14320	ENOG4105CHR	reductase
HM987_RS14330	ENOG4105EYW	Ion transport protein
HM987_RS14335	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HM987_RS14340	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HM987_RS14345	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HM987_RS14360	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HM987_RS14365	ENOG4105DGW	oligopeptidase A
HM987_RS14425	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HM987_RS14430	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HM987_RS14440	ENOG4107R8N	Glycosyl transferase, family 2
HM987_RS14470	ENOG4105DHJ	ABC, transporter
HM987_RS14495	ENOG4105CP2	von willebrand factor, type a
HM987_RS14520	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HM987_RS14540	ENOG4105C7S	Dehydrogenase
HM987_RS14550	ENOG4105KG3	cytidine deaminase
HM987_RS14565	ENOG4105E6M	Sulphatase-modifying factor protein
HM987_RS14570	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HM987_RS14575	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HM987_RS14595	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HM987_RS14605	ENOG4109015	Biopolymer transport protein exbD tolR
HM987_RS14610	ENOG4105M8K	biopolymer transport protein
HM987_RS14615	ENOG4105DN9	Na H antiporter
HM987_RS14630	ENOG4105C1G	acyl-Coa dehydrogenase
HM987_RS14635	ENOG4107QUV	Domain protein
HM987_RS14690	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HM987_RS14715	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HM987_RS14725	ENOG4105VPI	YqaE family transport protein
HM987_RS14730	ENOG4105WH1	Two component transcriptional regulator luxr family
HM987_RS14740	ENOG4105K63	Thioredoxin
HM987_RS14745	ENOG4105CRK	lysyL-tRNA synthetase
HM987_RS14780	ENOG4108Z12	YiaAB two helix domain-containing protein
HM987_RS14800	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HM987_RS14810	ENOG4105K6H	D-cysteine desulfhydrase
HM987_RS14835	ENOG4105CGP	Urocanate hydratase
HM987_RS14845	ENOG4105CHH	sulfate transporter
HM987_RS14850	ENOG4105VEQ	Cold shock protein
HM987_RS14855	ENOG4105KPY	Small multidrug resistance protein
HM987_RS14870	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HM987_RS14875	ENOG4105WH1	Two component transcriptional regulator luxr family
HM987_RS14880	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HM987_RS14930	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HM987_RS14935	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HM987_RS14940	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HM987_RS14945	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HM987_RS14950	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HM987_RS14955	ENOG4108UKI	Enoyl-CoA hydratase
HM987_RS14965	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HM987_RS14975	ENOG4105CGZ	zinc metallopeptidase
HM987_RS14980	ENOG4105CHU	acetyl-coa acetyltransferase
HM987_RS14985	ENOG4105DXM	phenylacetic acid degradation protein
HM987_RS15000	ENOG4105J0Q	Transcriptional regulator
HM987_RS15005	ENOG4105C7S	Dehydrogenase
HM987_RS15010	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HM987_RS15015	ENOG4105CPP	Dehydrogenase, E1 component
HM987_RS15030	ENOG4105EMN	RNA polymerase sigma factor
HM987_RS15045	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HM987_RS15055	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HM987_RS15060	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
HM987_RS15080	ENOG4105S2T	inner membrane protein YbcI
HM987_RS15085	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HM987_RS15090	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HM987_RS15095	ENOG4105CTQ	phosphohexokinase
HM987_RS15100	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HM987_RS15110	ENOG4105CHM	Aminotransferase
HM987_RS15115	ENOG4105CQC	Prephenate dehydratase
HM987_RS15120	ENOG4105CJ1	ABC, transporter
HM987_RS15125	ENOG4105C6K	Malic enzyme
HM987_RS15130	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HM987_RS15145	ENOG4105C6T	cysteine synthase
HM987_RS15150	ENOG4105D7W	serine acetyltransferase
HM987_RS15155	ENOG4105CAY	ferredoxin--nadp reductase
HM987_RS15160	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HM987_RS15165	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HM987_RS15175	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
HM987_RS15180	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HM987_RS15190	ENOG4105DA5	(ABC) transporter
HM987_RS15195	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HM987_RS15210	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HM987_RS15215	ENOG4105D9N	nucleoside
HM987_RS15225	ENOG4105C10	Electron transfer flavoprotein
HM987_RS15230	ENOG4105BZJ	Electron transfer flavoprotein
HM987_RS15235	ENOG4105CPP	Dehydrogenase, E1 component
HM987_RS15265	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HM987_RS15315	ENOG4105ZMH	deoxynucleoside kinase
HM987_RS15320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HM987_RS15335	ENOG4107PU6	Membrane
HM987_RS15340	ENOG4105DZ0	fad dependent oxidoreductase
HM987_RS15345	ENOG4108UW5	maltose o-acetyltransferase
HM987_RS15350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HM987_RS15355	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HM987_RS15365	ENOG4105CD3	dihydroorotase
HM987_RS15370	ENOG4105CMR	udp-glucose 4-epimerase
HM987_RS15375	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HM987_RS15400	ENOG4105DDG	Cyanophycinase
HM987_RS15465	ENOG4105ETE	Transcriptional regulator (LacI family
HM987_RS15545	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HM987_RS15570	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
HM987_RS15585	ENOG41088M2	Glycosyl transferase family 2
HM987_RS15595	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HM987_RS15625	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HM987_RS15630	ENOG4107IQ5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HM987_RS15660	ENOG4105CJ1	ABC, transporter
HM987_RS15675	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HM987_RS15685	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HM987_RS15700	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HM987_RS15705	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HM987_RS15710	ENOG4105CHR	reductase
HM987_RS15735	ENOG4107TDE	lipolytic protein G-D-S-L family
HM987_RS15745	ENOG4105E4I	Glycoside hydrolase family 28
HM987_RS15750	ENOG4105D9R	oxidoreductase
HM987_RS15755	ENOG4105F5H	Glycosyl Hydrolase Family 88
HM987_RS15825	ENOG4105ETE	Transcriptional regulator (LacI family
HM987_RS15830	ENOG4105CTX	dehydratase
HM987_RS15835	ENOG4107QZW	Altronate oxidoreductase
HM987_RS15840	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HM987_RS15850	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HM987_RS15855	ENOG4105D2H	Uronic isomerase
HM987_RS15880	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HM987_RS15890	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HM987_RS15915	ENOG41083X6	30S ribosomal protein S21
HM987_RS15920	ENOG4108Z0R	Transferase
HM987_RS15930	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HM987_RS15950	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HM987_RS15960	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HM987_RS15970	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HM987_RS15975	ENOG4105EV9	Alpha Beta Hydrolase
HM987_RS15985	ENOG41082T9	Membrane
HM987_RS15990	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HM987_RS15995	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HM987_RS16000	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HM987_RS16025	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HM987_RS16055	ENOG41083MR	nifu domain-containing protein
HM987_RS16070	ENOG41072GX	Peptidase M22 Glycoprotease
HM987_RS16085	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HM987_RS16090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HM987_RS16095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HM987_RS16100	ENOG4105C19	ABC transporter
HM987_RS16110	ENOG4108SJC	Membrane
HM987_RS16115	ENOG4108KF3	Electron transport protein SCO1 SenC
HM987_RS16135	ENOG4105CCU	oxidase (Subunit III)
HM987_RS16140	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HM987_RS16185	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HM987_RS16195	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HM987_RS16200	ENOG4105C6K	Malic enzyme
HM987_RS16215	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HM987_RS16250	ENOG4105JZI	cytochrome P450
HM987_RS16255	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HM987_RS16260	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HM987_RS16265	ENOG4105E2S	oxidase) subunit II
HM987_RS16290	ENOG4107SFQ	iron-sulfur binding
HM987_RS16310	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HM987_RS16315	ENOG4105CHV	Transcription elongation factor NusA
HM987_RS16320	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
HM987_RS16345	ENOG4105K63	Thioredoxin
HM987_RS16355	ENOG4105ENE	Histidine kinase
HM987_RS16360	ENOG4105DY9	regulatoR
HM987_RS16395	ENOG4108DIG	cyanophycin synthetase
HM987_RS16405	ENOG4105D44	asparaginase
HM987_RS16430	ENOG4105C2M	dna polymerase I
HM987_RS16470	ENOG4105DHU	Bile acid
HM987_RS16475	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HM987_RS16490	ENOG4105CCT	upf0313 protein
HM987_RS16495	ENOG4105C5H	ABC transporter
HM987_RS16520	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HM987_RS16530	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HM987_RS16535	ENOG4108UJD	30S ribosomal protein S9
HM987_RS16540	ENOG4105CE9	30S ribosomal protein S2
HM987_RS16545	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HM987_RS16550	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HM987_RS16555	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HM987_RS16570	ENOG4105C5S	asparaginyl-tRNA synthetase
HM987_RS16575	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HM987_RS16595	ENOG4109015	Biopolymer transport protein exbD tolR
HM987_RS16615	ENOG4105HDK	L-asparaginase
HM987_RS16620	ENOG4105F8V	Hydrolase, tatD family
HM987_RS16630	ENOG4107ZHV	Transcriptional regulator
HM987_RS16675	ENOG4105BZS	acriflavin resistance protein
HM987_RS16680	ENOG4105C9M	aspartyl-trna synthetase
HM987_RS16695	ENOG4105VEQ	Cold shock protein
HM987_RS16705	ENOG4108Z6B	deaminase
HM987_RS16715	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HM987_RS16775	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HM987_RS16780	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HM987_RS16785	ENOG4105DY9	regulatoR
HM987_RS16790	ENOG4108HRK	Histidine kinase
HM987_RS16810	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HM987_RS16860	ENOG4105CN1	protease
HM987_RS16875	ENOG4105C28	cystathionine
HM987_RS16880	ENOG4105C3R	Methionine synthase
HM987_RS16890	ENOG4105C3R	Methionine synthase
HM987_RS16895	ENOG4105SYT	Methylenetetrahydrofolate reductase
HM987_RS16900	ENOG4105E6M	Sulphatase-modifying factor protein
HM987_RS16905	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HM987_RS16930	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HM987_RS16935	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HM987_RS16945	ENOG4105F4R	Transcriptional regulator mode
HM987_RS16950	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HM987_RS16965	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HM987_RS16970	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HM987_RS16975	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HM987_RS16985	ENOG4105DTN	riboflavin biosynthesis protein ribF
HM987_RS16995	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HM987_RS17015	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HM987_RS17020	ENOG4105CJW	magnesium transporter
HM987_RS17030	ENOG4108JQ1	Dehydrogenase
HM987_RS17035	ENOG4105EWK	phytoene
HM987_RS17040	ENOG4105WH1	Two component transcriptional regulator luxr family
HM987_RS17075	ENOG4105CFH	Aspartokinase
HM987_RS17085	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HM987_RS17095	ENOG4108JA2	transcriptioN-repair coupling factor
HM987_RS17110	ENOG4109066	lysm domain bon superfamily protein
HM987_RS17120	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HM987_RS17130	ENOG4105KBX	Transcriptional regulator, TetR family
HM987_RS17140	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HM987_RS17160	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HM987_RS17185	ENOG41077A9	carbonic anhydrase
HM987_RS17190	ENOG4105CHH	sulfate transporter
HM987_RS17255	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HM987_RS17265	ENOG4107QM2	Aldo Keto reductase
HM987_RS17300	ENOG4105C26	Dehydrogenase
HM987_RS17320	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
HM987_RS17330	ENOG4108JQB	penicillin-binding protein 1C
HM987_RS17370	ENOG4105XIV	Mercuric transport protein, periplasmic component
HM987_RS17375	ENOG4108594	Permease of the drug metabolite transporter
HM987_RS17390	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HM987_RS17395	ENOG4105K46	50S ribosomal protein l27
HM987_RS17410	ENOG4105E33	succinate dehydrogenase
HM987_RS17440	ENOG4105DC7	peptidase M24
HM987_RS17445	ENOG4105M6F	mutator MutT protein
HM987_RS17450	ENOG4105CFI	type iii restriction protein res subunit
HM987_RS17455	ENOG4105CFH	Aspartokinase
HM987_RS17465	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HM987_RS17480	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HM987_RS17490	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HM987_RS17540	ENOG4105C9B	Cysteine desulfurase
HM987_RS17550	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HM987_RS17555	ENOG4105VG1	fes assembly suf system protein
HM987_RS17580	ENOG4108JQC	penicillin-binding protein 1A
HM987_RS17585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HM987_RS17625	ENOG4105CA9	Pyruvate kinase
HM987_RS17635	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HM987_RS17640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HM987_RS17645	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HM987_RS17655	ENOG4108B1Q	Ribonuclease
HM987_RS17680	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HM987_RS17690	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HM987_RS17695	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HM987_RS17715	ENOG4105BZU	Histidine kinase
HM987_RS17750	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HM987_RS17755	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HM987_RS17780	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HM987_RS17820	ENOG4105C27	TonB-dependent Receptor Plug
HM987_RS17825	ENOG4108RG0	uracil-dna glycosylase
HM987_RS17860	ENOG4107T8J	thymidine kinase
HM987_RS17865	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HM987_RS17870	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HM987_RS17875	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HM987_RS17900	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HM987_RS17945	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HM987_RS17960	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HM987_RS17965	ENOG41065KQ	synthase
HM987_RS17975	ENOG4105EWK	phytoene
HM987_RS17990	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HM987_RS18005	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HM987_RS18010	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HM987_RS18015	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HM987_RS18020	ENOG4105WXV	50S ribosomal protein L32
HM987_RS18030	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HM987_RS18035	ENOG4108R6K	riboflavin synthase, subunit alpha
HM987_RS18055	ENOG4105D75	Capsular exopolysaccharide family
HM987_RS18065	ENOG4105K64	Glycosyl transferase, family 2
HM987_RS18085	ENOG4105ECJ	Glycosyl Transferase
HM987_RS18135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HM987_RS18140	ENOG4105C5E	polysaccharide biosynthesis protein
HM987_RS18145	ENOG4105ESV	Glycosyl transferase, family 4
HM987_RS18190	ENOG4108ZVT	methylmalonyl-coA epimerase
HM987_RS18195	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HM987_RS18200	ENOG4105D60	lipoprotein releasing system transmembrane protein
HM987_RS18205	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HM987_RS18220	ENOG4107VAM	peptidase, m28
HM987_RS18235	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HM987_RS18240	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HM987_RS18250	ENOG4105C8F	Beta-lactamase domain protein
HM987_RS18270	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HM987_RS18275	ENOG4105CN1	protease
HM987_RS18285	ENOG4107YB6	acetyltransferase, (GNAT) family
HM987_RS18290	ENOG4105PGM	cation diffusion facilitator family transporter
HM987_RS18295	ENOG4108YZG	isomerase
HM987_RS18305	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HM987_RS18310	ENOG4105K8R	UPF0145 protein
HM987_RS18345	ENOG4105CX6	glutaminyL-tRNA synthetase
HM987_RS18375	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HM987_RS18385	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HM987_RS18390	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HM987_RS18410	ENOG4107QRG	dna polymerase iii
HM987_RS18415	ENOG4105BZA	Phosphoglycerate kinase
HM987_RS18420	ENOG4105K4H	Nlp p60 protein
HM987_RS18430	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HM987_RS18455	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HM987_RS18465	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HM987_RS18470	ENOG4107QQG	Dehydrogenase
HM987_RS18480	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HM987_RS18485	ENOG4105FAW	cDP-glucose 4,6-dehydratase
HM987_RS18530	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HM987_RS18550	ENOG4107T8Q	Glycosyl transferase (Group 1
HM987_RS18565	ENOG4105C12	Phosphoribosylglycinamide synthetase
HM987_RS18580	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HM987_RS18590	ENOG4105DKP	glycosyl transferase, family 9
HM987_RS18640	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HM987_RS18645	ENOG410842R	atp synthase
HM987_RS18650	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HM987_RS18655	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HM987_RS18660	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HM987_RS18670	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HM987_RS18695	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HM987_RS18700	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HM987_RS18725	ENOG4105NAU	thioesterase Superfamily protein
HM987_RS18765	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HM987_RS18775	ENOG4105E4C	Lytic transglycosylase catalytic
HM987_RS18780	ENOG4105MA4	psp1 domain protein
HM987_RS18785	ENOG410647Z	gliding motility-associated lipoprotein GldH
HM987_RS18790	ENOG4108JQC	penicillin-binding protein 1A
HM987_RS18795	ENOG4107QP7	CoA-transferase subunit A
HM987_RS18820	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HM987_RS18835	ENOG4105D52	delta-aminolevulinic acid dehydratase
HM987_RS18845	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HM987_RS18860	ENOG4105CZN	Potassium uptake protein
HM987_RS18865	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HM987_RS18875	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HM987_RS18880	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HM987_RS18905	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HM987_RS18920	ENOG4108HWS	Histidine kinase
HM987_RS18925	ENOG4105E39	Enoyl-CoA hydratase
HM987_RS18950	ENOG4108R6W	Transcriptional regulator, ARAC family
HM987_RS18975	ENOG4108Y6J	UPF0403 protein
HM987_RS18985	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HM987_RS19000	ENOG4107RBD	ABC, transporter
HM987_RS19005	ENOG4107RPQ	ABC transporter
HM987_RS19020	ENOG4105DIK	(ABC) transporter
HM987_RS19025	ENOG4105DSE	periplasmic solute binding protein
HM987_RS19045	ENOG4105CE1	Ferrous iron transport protein b
HM987_RS19055	ENOG4108KF3	Electron transport protein SCO1 SenC
HM987_RS19120	ENOG4107UNZ	domain protein
HM987_RS19135	ENOG4105W5Q	DNA repair protein (RadC
HM987_RS19190	ENOG4108Z6B	deaminase
HM987_RS19205	ENOG4105EXW	epimerase dehydratase
HM987_RS19225	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HM987_RS19235	ENOG4108UUM	single-stranded DNA-binding protein
HM987_RS19320	ENOG4105C7W	Xanthine dehydrogenase
HM987_RS19325	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HM987_RS19330	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HM987_RS19400	ENOG41090A1	ferritin
HM987_RS19445	ENOG4108S3W	Anti-feci sigma factor, fecr
HM987_RS19455	ENOG4105DGU	Histone deacetylase
HM987_RS19465	ENOG4105BZM	domain protein