locus-tag	class	description
H0I32_RS00035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H0I32_RS00045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0I32_RS00055	COG0492	ferredoxin-NADP+ reductase activity
H0I32_RS00065	COG0069	glutamate synthase activity
H0I32_RS00095	COG4251	negative regulation of phosphorylation
H0I32_RS00105	COG1733	regulation of RNA biosynthetic process
H0I32_RS00110	COG0778	Nitroreductase
H0I32_RS00140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0I32_RS00165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0I32_RS00165	COG0784	Response regulator, receiver
H0I32_RS00170	COG2807	transmembrane transport
H0I32_RS00185	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS00190	COG1278	Cold shock
H0I32_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS00210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H0I32_RS00220	COG4942	peptidase
H0I32_RS00235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H0I32_RS00240	COG1278	Cold shock
H0I32_RS00255	COG2814	Major facilitator Superfamily
H0I32_RS00260	COG0668	transmembrane transport
H0I32_RS00290	COG0668	transmembrane transport
H0I32_RS00300	COG0101	tRNA pseudouridine synthase activity
H0I32_RS00305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0I32_RS00305	COG0140	phosphoribosyl-ATP diphosphatase activity
H0I32_RS00310	COG0107	imidazoleglycerol-phosphate synthase activity
H0I32_RS00315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H0I32_RS00325	COG0131	Imidazoleglycerol-phosphate dehydratase
H0I32_RS00325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H0I32_RS00330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H0I32_RS00335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0I32_RS00340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0I32_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS00360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0I32_RS00365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS00370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H0I32_RS00375	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS00380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H0I32_RS00380	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H0I32_RS00385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS00390	COG1078	dGTPase activity
H0I32_RS00395	COG2204	response regulator
H0I32_RS00400	COG0802	atpase or kinase
H0I32_RS00425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H0I32_RS00430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0I32_RS00440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H0I32_RS00450	COG1522	sequence-specific DNA binding
H0I32_RS00500	COG0012	GTP binding
H0I32_RS00505	COG4251	negative regulation of phosphorylation
H0I32_RS00510	COG0784	Response regulator, receiver
H0I32_RS00550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0I32_RS00560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H0I32_RS00565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0I32_RS00620	COG1228	amidohydrolase
H0I32_RS00630	COG0010	Belongs to the arginase family
H0I32_RS00635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS00675	COG3279	Response regulator of the LytR AlgR family
H0I32_RS00695	COG3275	phosphorelay sensor kinase activity
H0I32_RS00735	COG4935	Belongs to the peptidase S8 family
H0I32_RS00735	COG1404	Belongs to the peptidase S8 family
H0I32_RS00745	COG3118	belongs to the thioredoxin family
H0I32_RS00780	COG1136	(ABC) transporter
H0I32_RS00780	COG0577	efflux transmembrane transporter activity
H0I32_RS00785	COG1136	(ABC) transporter
H0I32_RS00790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS00800	COG1703	isobutyryl-CoA mutase activity
H0I32_RS00810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS00810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS00815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS00820	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H0I32_RS00825	COG0511	ligase activity, forming carbon-carbon bonds
H0I32_RS00835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0I32_RS00840	COG0346	lactoylglutathione lyase activity
H0I32_RS00845	COG0095	Lipoate-protein ligase
H0I32_RS00850	COG1272	protein, Hemolysin III
H0I32_RS00865	COG1131	(ABC) transporter
H0I32_RS00870	COG1363	Peptidase, m42
H0I32_RS00895	COG2339	peptidase activity
H0I32_RS00905	COG0439	Biotin carboxylase
H0I32_RS00910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0I32_RS00915	COG1132	(ABC) transporter
H0I32_RS00920	COG2814	Major facilitator Superfamily
H0I32_RS00925	COG0009	L-threonylcarbamoyladenylate synthase
H0I32_RS00945	COG3279	Response regulator of the LytR AlgR family
H0I32_RS00950	COG3275	phosphorelay sensor kinase activity
H0I32_RS00980	COG0438	transferase activity, transferring glycosyl groups
H0I32_RS00985	COG1472	Belongs to the glycosyl hydrolase 3 family
H0I32_RS00990	COG3830	Belongs to the UPF0237 family
H0I32_RS00990	COG0560	Phosphoserine phosphatase
H0I32_RS01015	COG2181	nitrate reductase activity
H0I32_RS01015	COG0247	lactate metabolic process
H0I32_RS01025	COG0247	lactate metabolic process
H0I32_RS01025	COG2181	nitrate reductase activity
H0I32_RS01030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0I32_RS01035	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0I32_RS01045	COG0251	oxidation-reduction process
H0I32_RS01065	COG4251	negative regulation of phosphorylation
H0I32_RS01075	COG0463	Glycosyl transferase, family 2
H0I32_RS01115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0I32_RS01120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0I32_RS01140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0I32_RS01190	COG0156	8-amino-7-oxononanoate synthase activity
H0I32_RS01205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H0I32_RS01220	COG1393	Belongs to the ArsC family
H0I32_RS01235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0I32_RS01245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0I32_RS01260	COG0745	RESPONSE REGULATOR receiver
H0I32_RS01265	COG5002	protein histidine kinase activity
H0I32_RS01270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0I32_RS01305	COG3237	CsbD-like
H0I32_RS01310	COG1309	transcriptional regulator
H0I32_RS01320	COG0778	Nitroreductase
H0I32_RS01325	COG2130	NADP-dependent
H0I32_RS01330	COG1979	alcohol dehydrogenase
H0I32_RS01345	COG0352	thiamine-phosphate diphosphorylase activity
H0I32_RS01355	COG2066	Belongs to the glutaminase family
H0I32_RS01365	COG2308	Evidence 4 Homologs of previously reported genes of
H0I32_RS01365	COG2307	Protein conserved in bacteria
H0I32_RS01385	COG2308	Evidence 4 Homologs of previously reported genes of
H0I32_RS01390	COG1902	pentaerythritol trinitrate reductase activity
H0I32_RS01395	COG1289	transmembrane transporter activity
H0I32_RS01415	COG2176	DNA-directed DNA polymerase activity
H0I32_RS01425	COG1136	(ABC) transporter
H0I32_RS01425	COG0577	efflux transmembrane transporter activity
H0I32_RS01430	COG4181	ATPase activity
H0I32_RS01440	COG0513	Belongs to the DEAD box helicase family
H0I32_RS01450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0I32_RS01465	COG2274	protein secretion by the type I secretion system
H0I32_RS01480	COG2373	Large extracellular alpha-helical protein
H0I32_RS01485	COG1278	Cold shock
H0I32_RS01545	COG1187	pseudouridine synthase activity
H0I32_RS01555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0I32_RS01575	COG0022	dehydrogenase e1 component
H0I32_RS01595	COG0813	purine-nucleoside phosphorylase activity
H0I32_RS01605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H0I32_RS01610	COG1288	antiporter activity
H0I32_RS01615	COG1193	negative regulation of DNA recombination
H0I32_RS01620	COG3011	Protein conserved in bacteria
H0I32_RS01675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H0I32_RS01680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H0I32_RS01685	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H0I32_RS01690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H0I32_RS01695	COG0561	phosphatase activity
H0I32_RS01705	COG3279	Response regulator of the LytR AlgR family
H0I32_RS01725	COG0305	Participates in initiation and elongation during chromosome replication
H0I32_RS01730	COG0825	malonyl-CoA metabolic process
H0I32_RS01745	COG0343	queuine tRNA-ribosyltransferase activity
H0I32_RS01750	COG3959	Transketolase, thiamine diphosphate binding domain
H0I32_RS01755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H0I32_RS01780	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H0I32_RS01785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H0I32_RS01810	COG1233	COG1233 Phytoene dehydrogenase and related
H0I32_RS01825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS01845	COG0714	Associated with various cellular activities
H0I32_RS01850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0I32_RS01860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0I32_RS01885	COG0308	aminopeptidase N
H0I32_RS01890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0I32_RS01905	COG0427	acetyl-CoA hydrolase
H0I32_RS01965	COG0339	signal peptide processing
H0I32_RS01975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0I32_RS01980	COG1461	Dihydroxyacetone kinase
H0I32_RS01985	COG2376	Dihydroxyacetone kinase
H0I32_RS02010	COG1454	alcohol dehydrogenase
H0I32_RS02025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H0I32_RS02035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0I32_RS02050	COG0742	ribosomal rna small subunit methyltransferase
H0I32_RS02060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0I32_RS02085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H0I32_RS02105	COG2885	chlorophyll binding
H0I32_RS02125	COG0259	pyridoxamine-phosphate oxidase activity
H0I32_RS02135	COG1234	tRNA 3'-trailer cleavage
H0I32_RS02145	COG0540	Belongs to the ATCase OTCase family
H0I32_RS02150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H0I32_RS02165	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H0I32_RS02175	COG1705	Flagellar rod assembly protein muramidase FlgJ
H0I32_RS02175	COG1388	LysM domain
H0I32_RS02180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H0I32_RS02200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0I32_RS02200	COG0047	phosphoribosylformylglycinamidine synthase activity
H0I32_RS02205	COG4585	Histidine kinase
H0I32_RS02210	COG2197	response regulator
H0I32_RS02215	COG1862	Preprotein translocase
H0I32_RS02225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H0I32_RS02230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0I32_RS02235	COG1132	(ABC) transporter
H0I32_RS02245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0I32_RS02265	COG0542	response to heat
H0I32_RS02275	COG2986	histidine ammonia-lyase
H0I32_RS02280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS02285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS02290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0I32_RS02295	COG0527	aspartate kinase activity
H0I32_RS02295	COG0460	homoserine dehydrogenase
H0I32_RS02300	COG0083	homoserine kinase activity
H0I32_RS02310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0I32_RS02330	COG0662	Cupin 2, conserved barrel domain protein
H0I32_RS02330	COG2207	Transcriptional regulator
H0I32_RS02345	COG0516	GMP reductase activity
H0I32_RS02345	COG0517	IMP dehydrogenase activity
H0I32_RS02360	COG3487	Iron-regulated protein
H0I32_RS02390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0I32_RS02440	COG0167	dihydroorotate dehydrogenase activity
H0I32_RS02445	COG0589	response to stress
H0I32_RS02450	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0I32_RS02480	COG1846	Transcriptional regulator
H0I32_RS02485	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0I32_RS02485	COG1024	Enoyl-CoA hydratase
H0I32_RS02490	COG0183	Belongs to the thiolase family
H0I32_RS02500	COG1960	acyl-CoA dehydrogenase activity
H0I32_RS02520	COG3387	PFAM Glycoside hydrolase 15-related
H0I32_RS02555	COG0783	Belongs to the Dps family
H0I32_RS02595	COG2205	protein histidine kinase activity
H0I32_RS02595	COG0784	Response regulator, receiver
H0I32_RS02620	COG0492	ferredoxin-NADP+ reductase activity
H0I32_RS02690	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS02730	COG1858	cytochrome C peroxidase
H0I32_RS02770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS02785	COG4206	TonB-dependent receptor
H0I32_RS02815	COG0572	uridine kinase
H0I32_RS02825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS02830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS02830	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS02835	COG0612	Peptidase, M16
H0I32_RS02840	COG1192	Involved in chromosome partitioning
H0I32_RS02845	COG1475	DNA binding
H0I32_RS02855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H0I32_RS02860	COG0681	Belongs to the peptidase S26 family
H0I32_RS02890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0I32_RS02905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H0I32_RS02915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H0I32_RS02940	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H0I32_RS02955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0I32_RS02980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H0I32_RS02985	COG4166	transmembrane transport
H0I32_RS03000	COG0254	rRNA binding
H0I32_RS03015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0I32_RS03020	COG1132	(ABC) transporter
H0I32_RS03025	COG1595	DNA-templated transcription, initiation
H0I32_RS03100	COG1595	DNA-templated transcription, initiation
H0I32_RS03110	COG3279	Response regulator of the LytR AlgR family
H0I32_RS03125	COG3275	phosphorelay sensor kinase activity
H0I32_RS03155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H0I32_RS03160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H0I32_RS03170	COG1674	ftsk spoiiie
H0I32_RS03185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0I32_RS03185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0I32_RS03190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0I32_RS03205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H0I32_RS03210	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H0I32_RS03220	COG0626	cystathionine gamma-synthase activity
H0I32_RS03225	COG1333	cytochrome c biogenesis protein
H0I32_RS03225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H0I32_RS03230	COG1970	mechanosensitive ion channel activity
H0I32_RS03245	COG0513	Belongs to the DEAD box helicase family
H0I32_RS03260	COG2217	Heavy metal translocating P-type atpase
H0I32_RS03270	COG3278	Belongs to the heme-copper respiratory oxidase family
H0I32_RS03285	COG0348	domain, Protein
H0I32_RS03305	COG1073	alpha beta
H0I32_RS03350	COG1482	cell wall glycoprotein biosynthetic process
H0I32_RS03360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H0I32_RS03370	COG2885	chlorophyll binding
H0I32_RS03385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H0I32_RS03395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H0I32_RS03400	COG0085	RNA polymerase activity
H0I32_RS03405	COG0222	ribosome binding
H0I32_RS03410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H0I32_RS03415	COG0081	regulation of translation
H0I32_RS03420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H0I32_RS03440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H0I32_RS03465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H0I32_RS03470	COG4974	Belongs to the 'phage' integrase family
H0I32_RS03485	COG1115	amino acid carrier protein
H0I32_RS03490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0I32_RS03505	COG2205	protein histidine kinase activity
H0I32_RS03505	COG0784	Response regulator, receiver
H0I32_RS03515	COG2264	protein methyltransferase activity
H0I32_RS03530	COG0577	efflux transmembrane transporter activity
H0I32_RS03535	COG3876	Protein conserved in bacteria
H0I32_RS03540	COG0584	glycerophosphoryl diester phosphodiesterase
H0I32_RS03565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H0I32_RS03580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H0I32_RS03605	COG4452	Inner membrane protein CreD
H0I32_RS03620	COG0300	oxidoreductase activity
H0I32_RS03635	COG1858	cytochrome C peroxidase
H0I32_RS03670	COG1047	Peptidyl-prolyl cis-trans
H0I32_RS03675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0I32_RS03680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0I32_RS03700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0I32_RS03715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0I32_RS03720	COG0512	Glutamine amidotransferase of anthranilate synthase
H0I32_RS03720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0I32_RS03725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0I32_RS03730	COG0134	indole-3-glycerol-phosphate synthase activity
H0I32_RS03735	COG0135	phosphoribosylanthranilate isomerase activity
H0I32_RS03740	COG0133	tryptophan synthase activity
H0I32_RS03745	COG2884	Cell division ATP-binding protein ftsE
H0I32_RS03750	COG0463	Glycosyl transferase, family 2
H0I32_RS03750	COG1216	Glycosyl transferase, family 2
H0I32_RS03755	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS03765	COG0438	transferase activity, transferring glycosyl groups
H0I32_RS03780	COG2244	polysaccharide biosynthetic process
H0I32_RS03805	COG1217	gtp-binding protein TYPA
H0I32_RS03815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H0I32_RS03835	COG0492	ferredoxin-NADP+ reductase activity
H0I32_RS03850	COG1595	DNA-templated transcription, initiation
H0I32_RS03860	COG1703	isobutyryl-CoA mutase activity
H0I32_RS03860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS03860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0I32_RS03865	COG0788	formyltetrahydrofolate deformylase activity
H0I32_RS03880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H0I32_RS03885	COG0284	orotidine-5'-phosphate decarboxylase activity
H0I32_RS03890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H0I32_RS03895	COG1129	ABC transporter
H0I32_RS03905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H0I32_RS03915	COG0174	glutamine synthetase
H0I32_RS03940	COG2356	endonuclease I
H0I32_RS03960	COG0419	ATPase involved in DNA repair
H0I32_RS03965	COG0420	3'-5' exonuclease activity
H0I32_RS03970	COG3550	peptidyl-serine autophosphorylation
H0I32_RS03980	COG1396	sequence-specific DNA binding
H0I32_RS04015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0I32_RS04145	COG0730	response to heat
H0I32_RS04165	COG2264	protein methyltransferase activity
H0I32_RS04175	COG0149	triose-phosphate isomerase activity
H0I32_RS04180	COG0601	transmembrane transport
H0I32_RS04195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0I32_RS04220	COG1132	(ABC) transporter
H0I32_RS04225	COG0101	tRNA pseudouridine synthase activity
H0I32_RS04265	COG4251	negative regulation of phosphorylation
H0I32_RS04270	COG0784	Response regulator, receiver
H0I32_RS04365	COG0488	(ABC) transporter
H0I32_RS04375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0I32_RS04395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0I32_RS04415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H0I32_RS04445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H0I32_RS04450	COG0459	protein refolding
H0I32_RS04460	COG2855	membrane
H0I32_RS04465	COG0583	DNA-binding transcription factor activity
H0I32_RS04495	COG1956	GAF domain-containing protein
H0I32_RS04505	COG0138	bifunctional purine biosynthesis protein purh
H0I32_RS04510	COG1077	Cell shape determining protein MreB Mrl
H0I32_RS04525	COG0768	penicillin binding
H0I32_RS04530	COG0772	Belongs to the SEDS family
H0I32_RS04535	COG0525	valine-tRNA ligase activity
H0I32_RS04545	COG0436	Aminotransferase
H0I32_RS04550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H0I32_RS04555	COG1595	DNA-templated transcription, initiation
H0I32_RS04575	COG1216	Glycosyl transferase, family 2
H0I32_RS04590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0I32_RS04595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0I32_RS04605	COG1663	tetraacyldisaccharide 4'-kinase activity
H0I32_RS04610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0I32_RS04635	COG0784	Response regulator, receiver
H0I32_RS04635	COG2205	protein histidine kinase activity
H0I32_RS04640	COG3844	kynureninase activity
H0I32_RS04650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0I32_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS04675	COG0662	Cupin 2, conserved barrel domain protein
H0I32_RS04700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0I32_RS04730	COG3340	Belongs to the peptidase S51 family
H0I32_RS04750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0I32_RS04760	COG0427	acetyl-CoA hydrolase
H0I32_RS04780	COG2226	methyltransferase
H0I32_RS04785	COG2363	Small membrane protein
H0I32_RS04805	COG3279	Response regulator of the LytR AlgR family
H0I32_RS04810	COG3275	phosphorelay sensor kinase activity
H0I32_RS04845	COG3275	phosphorelay sensor kinase activity
H0I32_RS04850	COG1477	protein flavinylation
H0I32_RS04860	COG3447	MASE1 domain protein
H0I32_RS04860	COG5001	Diguanylate cyclase
H0I32_RS04860	COG5002	protein histidine kinase activity
H0I32_RS04865	COG0643	Histidine kinase
H0I32_RS04865	COG0784	Response regulator, receiver
H0I32_RS04865	COG2198	Histidine kinase
H0I32_RS04885	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H0I32_RS04890	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H0I32_RS04895	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H0I32_RS04900	COG1805	sodium ion transport
H0I32_RS04915	COG2967	ApaG domain
H0I32_RS04920	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS04935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS04945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0I32_RS04960	COG0357	Ribosomal RNA small subunit methyltransferase G
H0I32_RS04965	COG3239	Fatty acid desaturase
H0I32_RS04970	COG0436	Aminotransferase
H0I32_RS04995	COG0569	domain protein
H0I32_RS05000	COG2226	methyltransferase
H0I32_RS05010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0I32_RS05020	COG0191	fructose-bisphosphate aldolase activity
H0I32_RS05025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H0I32_RS05030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H0I32_RS05035	COG1185	polyribonucleotide nucleotidyltransferase activity
H0I32_RS05045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H0I32_RS05050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H0I32_RS05055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H0I32_RS05065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0I32_RS05070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0I32_RS05090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0I32_RS05105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0I32_RS05155	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS05165	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS05175	COG1696	Membrane protein involved in D-alanine export
H0I32_RS05200	COG3955	Domain of unknown function (DUF1919)
H0I32_RS05205	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS05245	COG0529	Catalyzes the synthesis of activated sulfate
H0I32_RS05255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0I32_RS05260	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H0I32_RS05290	COG3228	Belongs to the MtfA family
H0I32_RS05295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0I32_RS05300	COG0668	transmembrane transport
H0I32_RS05310	COG1538	Outer membrane efflux protein
H0I32_RS05320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS05330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0I32_RS05340	COG0069	glutamate synthase activity
H0I32_RS05345	COG1289	transmembrane transporter activity
H0I32_RS05360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H0I32_RS05380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0I32_RS05385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H0I32_RS05395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0I32_RS05485	COG0702	epimerase
H0I32_RS05490	COG4771	TonB-dependent receptor
H0I32_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS05525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0I32_RS05530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0I32_RS05540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H0I32_RS05550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0I32_RS05550	COG3321	synthase
H0I32_RS05550	COG4221	oxidoreductase activity
H0I32_RS05550	COG0300	oxidoreductase activity
H0I32_RS05560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0I32_RS05565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0I32_RS05595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H0I32_RS05600	COG0463	Glycosyl transferase, family 2
H0I32_RS05635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H0I32_RS05650	COG1428	Deoxynucleoside kinase
H0I32_RS05670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H0I32_RS05675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0I32_RS05685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0I32_RS05715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0I32_RS05725	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0I32_RS05730	COG0596	Alpha beta hydrolase
H0I32_RS05735	COG1950	PFAM Membrane protein of
H0I32_RS05740	COG0544	peptidyl-prolyl cis-trans isomerase activity
H0I32_RS05745	COG0740	serine-type endopeptidase activity
H0I32_RS05750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H0I32_RS05765	COG2204	response regulator
H0I32_RS05770	COG3275	phosphorelay sensor kinase activity
H0I32_RS05805	COG0668	transmembrane transport
H0I32_RS05810	COG1214	PFAM Peptidase M22, glycoprotease
H0I32_RS05825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS05830	COG0577	efflux transmembrane transporter activity
H0I32_RS05830	COG1136	(ABC) transporter
H0I32_RS05835	COG0577	efflux transmembrane transporter activity
H0I32_RS05835	COG1136	(ABC) transporter
H0I32_RS05840	COG1136	(ABC) transporter
H0I32_RS05850	COG2322	membrane
H0I32_RS05855	COG1999	signal sequence binding
H0I32_RS05875	COG1845	cytochrome c oxidase, subunit III
H0I32_RS05880	COG0109	protoheme IX farnesyltransferase activity
H0I32_RS05905	COG0509	glycine decarboxylation via glycine cleavage system
H0I32_RS05915	COG0632	four-way junction helicase activity
H0I32_RS05920	COG0280	phosphate acetyltransferase
H0I32_RS05920	COG0281	malic enzyme
H0I32_RS05925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0I32_RS05930	COG2124	cytochrome p450
H0I32_RS05935	COG2255	four-way junction helicase activity
H0I32_RS05940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0I32_RS05945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0I32_RS05965	COG3743	rRNA binding
H0I32_RS05965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H0I32_RS05970	COG0437	4 iron, 4 sulfur cluster binding
H0I32_RS05985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H0I32_RS05990	COG2251	uridine kinase activity
H0I32_RS05990	COG0195	Participates in both transcription termination and antitermination
H0I32_RS05995	COG0779	Required for maturation of 30S ribosomal subunits
H0I32_RS06020	COG3118	belongs to the thioredoxin family
H0I32_RS06025	COG1408	metallophosphoesterase
H0I32_RS06045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0I32_RS06045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0I32_RS06060	COG1061	Type III restriction enzyme res subunit
H0I32_RS06065	COG1032	radical SAM domain protein
H0I32_RS06070	COG0488	(ABC) transporter
H0I32_RS06080	COG0009	L-threonylcarbamoyladenylate synthase
H0I32_RS06085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H0I32_RS06090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0I32_RS06095	COG0052	Belongs to the universal ribosomal protein uS2 family
H0I32_RS06100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H0I32_RS06105	COG0528	UMP kinase activity
H0I32_RS06110	COG0233	cytoplasmic translational termination
H0I32_RS06145	COG0017	Asparaginyl-tRNA synthetase
H0I32_RS06150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H0I32_RS06170	COG0848	biopolymer transport protein
H0I32_RS06180	COG0811	peptide transport
H0I32_RS06190	COG0252	asparaginase activity
H0I32_RS06195	COG0084	hydrolase, TatD family'
H0I32_RS06245	COG0567	Dehydrogenase, E1 component
H0I32_RS06265	COG4263	nitrous-oxide reductase activity
H0I32_RS06335	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
H0I32_RS06340	COG1959	2 iron, 2 sulfur cluster binding
H0I32_RS06355	COG1309	transcriptional regulator
H0I32_RS06375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H0I32_RS06390	COG1278	Cold shock
H0I32_RS06400	COG0590	tRNA wobble adenosine to inosine editing
H0I32_RS06410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H0I32_RS06415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H0I32_RS06465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0I32_RS06480	COG2095	MarC family integral membrane protein
H0I32_RS06495	COG0793	Belongs to the peptidase S41A family
H0I32_RS06515	COG1410	methionine synthase
H0I32_RS06515	COG0646	methionine synthase
H0I32_RS06525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0I32_RS06550	COG0702	epimerase
H0I32_RS06555	COG4771	TonB-dependent receptor
H0I32_RS06560	COG1609	Transcriptional regulator
H0I32_RS06565	COG0800	Aldolase
H0I32_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS06585	COG2271	Major facilitator Superfamily
H0I32_RS06590	COG2186	Transcriptional regulator
H0I32_RS06600	COG0702	epimerase
H0I32_RS06605	COG4771	TonB-dependent receptor
H0I32_RS06655	COG0588	phosphoglycerate mutase activity
H0I32_RS06660	COG0028	Belongs to the TPP enzyme family
H0I32_RS06670	COG1017	nitric oxide dioxygenase activity
H0I32_RS06670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0I32_RS06675	COG0783	Belongs to the Dps family
H0I32_RS06680	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0I32_RS06680	COG1024	Enoyl-CoA hydratase
H0I32_RS06685	COG2095	MarC family integral membrane protein
H0I32_RS06690	COG0531	amino acid
H0I32_RS06695	COG2814	Major facilitator Superfamily
H0I32_RS06710	COG0745	RESPONSE REGULATOR receiver
H0I32_RS06715	COG5002	protein histidine kinase activity
H0I32_RS06735	COG2205	protein histidine kinase activity
H0I32_RS06735	COG0784	Response regulator, receiver
H0I32_RS06750	COG1785	Belongs to the alkaline phosphatase family
H0I32_RS06765	COG1136	(ABC) transporter
H0I32_RS06770	COG0523	cobalamin synthesis protein
H0I32_RS06775	COG0302	gtp cyclohydrolase
H0I32_RS06795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0I32_RS06800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H0I32_RS06805	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0I32_RS06810	COG0322	excinuclease ABC activity
H0I32_RS06815	COG0189	ligase activity
H0I32_RS06815	COG4067	protein conserved in archaea
H0I32_RS06820	COG0189	ligase activity
H0I32_RS06830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0I32_RS06835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H0I32_RS06850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0I32_RS06855	COG2133	pyrroloquinoline quinone binding
H0I32_RS06855	COG5183	chlorophyll binding
H0I32_RS06860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H0I32_RS06880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H0I32_RS06885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H0I32_RS06890	COG0297	glycogen (starch) synthase activity
H0I32_RS06895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0I32_RS06905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H0I32_RS06920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0I32_RS06935	COG3655	Transcriptional regulator
H0I32_RS06980	COG2268	Band 7 protein
H0I32_RS07010	COG1381	Involved in DNA repair and RecF pathway recombination
H0I32_RS07020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0I32_RS07030	COG0626	cystathionine gamma-synthase activity
H0I32_RS07065	COG1561	YicC-like family, N-terminal region
H0I32_RS07070	COG0194	GDP metabolic process
H0I32_RS07075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H0I32_RS07080	COG0792	nuclease activity
H0I32_RS07095	COG1619	proteins homologs of microcin C7 resistance protein MccF
H0I32_RS07100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0I32_RS07100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0I32_RS07150	COG0123	including yeast histone deacetylase and acetoin utilization protein
H0I32_RS07155	COG1528	Iron-storage protein
H0I32_RS07165	COG0629	single-stranded DNA binding
H0I32_RS07235	COG0656	L-ascorbic acid biosynthetic process
H0I32_RS07245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H0I32_RS07260	COG0288	reversible hydration of carbon dioxide
H0I32_RS07270	COG0659	secondary active sulfate transmembrane transporter activity
H0I32_RS07295	COG2304	oxidoreductase activity
H0I32_RS07300	COG2304	oxidoreductase activity
H0I32_RS07315	COG0714	Associated with various cellular activities
H0I32_RS07325	COG4989	oxidoreductase activity
H0I32_RS07330	COG4221	oxidoreductase activity
H0I32_RS07355	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS07375	COG4953	penicillin-binding protein 1C
H0I32_RS07415	COG0612	Peptidase, M16
H0I32_RS07420	COG0612	Peptidase, M16
H0I32_RS07425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H0I32_RS07430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H0I32_RS07440	COG4771	TonB-dependent receptor
H0I32_RS07450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H0I32_RS07455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0I32_RS07460	COG1053	succinate dehydrogenase
H0I32_RS07470	COG2985	domain, Protein
H0I32_RS07470	COG0490	domain, Protein
H0I32_RS07475	COG0006	proline dipeptidase activity
H0I32_RS07480	COG0527	aspartate kinase activity
H0I32_RS07495	COG0596	Alpha beta hydrolase
H0I32_RS07510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0I32_RS07520	COG0316	Belongs to the HesB IscA family
H0I32_RS07525	COG0719	Fe-S assembly protein
H0I32_RS07535	COG0396	ATPase activity
H0I32_RS07540	COG0719	Fe-S assembly protein
H0I32_RS07545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0I32_RS07555	COG2166	iron-sulfur cluster assembly
H0I32_RS07560	COG2151	metal-sulfur cluster biosynthetic enzyme
H0I32_RS07580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H0I32_RS07585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0I32_RS07615	COG2954	triphosphatase activity
H0I32_RS07620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0I32_RS07625	COG0469	pyruvate kinase activity
H0I32_RS07635	COG0571	ribonuclease III activity
H0I32_RS07640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0I32_RS07645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0I32_RS07655	COG0328	RNA-DNA hybrid ribonuclease activity
H0I32_RS07655	COG3341	Caulimovirus viroplasmin
H0I32_RS07670	COG0351	phosphomethylpyrimidine kinase
H0I32_RS07670	COG0352	thiamine-phosphate diphosphorylase activity
H0I32_RS07705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H0I32_RS07720	COG3842	ATPase activity
H0I32_RS07725	COG1505	serine-type exopeptidase activity
H0I32_RS07730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H0I32_RS07735	COG1970	mechanosensitive ion channel activity
H0I32_RS07740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0I32_RS07745	COG1435	thymidine kinase activity
H0I32_RS07760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H0I32_RS07770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0I32_RS07775	COG1573	uracil-dna glycosylase
H0I32_RS07790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0I32_RS07790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H0I32_RS07805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS07810	COG0720	synthase
H0I32_RS07840	COG5002	protein histidine kinase activity
H0I32_RS07840	COG2198	Histidine kinase
H0I32_RS07840	COG0784	Response regulator, receiver
H0I32_RS07880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0I32_RS07890	COG0439	Biotin carboxylase
H0I32_RS07895	COG0511	ligase activity, forming carbon-carbon bonds
H0I32_RS07900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0I32_RS07905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H0I32_RS07915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0I32_RS07935	COG1609	Transcriptional regulator
H0I32_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS07945	COG1312	Catalyzes the dehydration of D-mannonate
H0I32_RS07950	COG1904	glucuronate isomerase
H0I32_RS07960	COG5002	protein histidine kinase activity
H0I32_RS07975	COG0346	lactoylglutathione lyase activity
H0I32_RS07980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H0I32_RS07985	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0I32_RS08010	COG0481	GTPase activity
H0I32_RS08025	COG3263	regulation of cellular component size
H0I32_RS08035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0I32_RS08055	COG0594	ribonuclease P activity
H0I32_RS08060	COG0793	Belongs to the peptidase S41A family
H0I32_RS08070	COG2153	protein acetylation
H0I32_RS08075	COG1230	cation diffusion facilitator family transporter
H0I32_RS08080	COG0698	ribose 5-phosphate isomerase
H0I32_RS08085	COG0557	exoribonuclease II activity
H0I32_RS08090	COG0393	Putative heavy-metal-binding
H0I32_RS08130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0I32_RS08145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0I32_RS08155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H0I32_RS08160	COG0445	tRNA wobble uridine modification
H0I32_RS08165	COG2226	methyltransferase
H0I32_RS08175	COG0470	DNA polymerase III
H0I32_RS08180	COG0126	phosphoglycerate kinase activity
H0I32_RS08190	COG0791	NLP P60 protein
H0I32_RS08190	COG1388	LysM domain
H0I32_RS08230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H0I32_RS08245	COG2244	polysaccharide biosynthetic process
H0I32_RS08310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H0I32_RS08325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0I32_RS08375	COG0356	it plays a direct role in the translocation of protons across the membrane
H0I32_RS08380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H0I32_RS08385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H0I32_RS08390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H0I32_RS08395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H0I32_RS08400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H0I32_RS08420	COG0756	dUTP diphosphatase activity
H0I32_RS08425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H0I32_RS08460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H0I32_RS08460	COG0758	DNA mediated transformation
H0I32_RS08475	COG0180	Tryptophanyl-tRNA synthetase
H0I32_RS08500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H0I32_RS08520	COG0826	peptidase U32
H0I32_RS08530	COG1774	PSP1 C-terminal conserved region
H0I32_RS08540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H0I32_RS08545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0I32_RS08575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0I32_RS08580	COG1253	flavin adenine dinucleotide binding
H0I32_RS08600	COG1522	sequence-specific DNA binding
H0I32_RS08620	COG0113	porphobilinogen synthase activity
H0I32_RS08630	COG3012	SEC-C Motif Domain Protein
H0I32_RS08645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H0I32_RS08650	COG0569	domain protein
H0I32_RS08655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0I32_RS08660	COG0181	hydroxymethylbilane synthase activity
H0I32_RS08665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H0I32_RS08715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H0I32_RS08725	COG1981	membrane
H0I32_RS08730	COG5000	phosphorelay sensor kinase activity
H0I32_RS08735	COG1024	Enoyl-CoA hydratase
H0I32_RS08750	COG2207	Transcriptional regulator
H0I32_RS08760	COG1418	mRNA catabolic process
H0I32_RS08790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0I32_RS08795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0I32_RS08800	COG1121	(ABC) transporter
H0I32_RS08805	COG0803	Belongs to the bacterial solute-binding protein 9 family
H0I32_RS08820	COG4771	TonB-dependent receptor
H0I32_RS08850	COG1999	signal sequence binding
H0I32_RS08905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0I32_RS08910	COG2239	Acts as a magnesium transporter
H0I32_RS08915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0I32_RS08920	COG1233	COG1233 Phytoene dehydrogenase and related
H0I32_RS08945	COG0527	aspartate kinase activity
H0I32_RS08955	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H0I32_RS08965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0I32_RS08990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H0I32_RS09010	COG0517	IMP dehydrogenase activity
H0I32_RS09010	COG0516	GMP reductase activity
H0I32_RS09025	COG3590	peptidase
H0I32_RS09035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0I32_RS09040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H0I32_RS09050	COG0196	riboflavin kinase activity
H0I32_RS09060	COG0193	aminoacyl-tRNA hydrolase activity
H0I32_RS09100	COG3483	tryptophan 2,3-dioxygenase activity
H0I32_RS09110	COG0166	Belongs to the GPI family
H0I32_RS09125	COG4206	TonB-dependent receptor
H0I32_RS09125	COG1629	transport
H0I32_RS09145	COG1194	a g-specific adenine glycosylase
H0I32_RS09150	COG0776	regulation of translation
H0I32_RS09155	COG1530	ribonuclease E activity
H0I32_RS09170	COG0686	Belongs to the AlaDH PNT family
H0I32_RS09180	COG0495	leucyl-tRNA aminoacylation
H0I32_RS09185	COG2177	Part of the ABC transporter FtsEX involved in
H0I32_RS09200	COG1968	undecaprenyl-diphosphatase activity
H0I32_RS09205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0I32_RS09220	COG0519	Catalyzes the synthesis of GMP from XMP
H0I32_RS09225	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0I32_RS09235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0I32_RS09240	COG3852	Histidine kinase
H0I32_RS09255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0I32_RS09270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H0I32_RS09295	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H0I32_RS09305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0I32_RS09310	COG4717	serine-type aminopeptidase activity
H0I32_RS09315	COG0436	Aminotransferase
H0I32_RS09330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0I32_RS09350	COG0423	glycine-tRNA ligase activity
H0I32_RS09380	COG2072	flavoprotein involved in K transport
H0I32_RS09390	COG0708	Exodeoxyribonuclease III
H0I32_RS09395	COG1360	Flagellar Motor Protein
H0I32_RS09400	COG0667	Aldo Keto reductase
H0I32_RS09405	COG1522	sequence-specific DNA binding
H0I32_RS09415	COG2363	Small membrane protein
H0I32_RS09420	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H0I32_RS09435	COG0463	Glycosyl transferase, family 2
H0I32_RS09440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H0I32_RS09455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0I32_RS09470	COG0745	RESPONSE REGULATOR receiver
H0I32_RS09475	COG5002	protein histidine kinase activity
H0I32_RS09480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H0I32_RS09485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0I32_RS09500	COG0489	protein tyrosine kinase activity
H0I32_RS09505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H0I32_RS09510	COG0492	ferredoxin-NADP+ reductase activity
H0I32_RS09515	COG0633	Ferredoxin
H0I32_RS09530	COG1960	acyl-CoA dehydrogenase activity
H0I32_RS09535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H0I32_RS09540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0I32_RS09545	COG0228	four-way junction DNA binding
H0I32_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS09580	COG0596	Alpha beta hydrolase
H0I32_RS09605	COG4585	Histidine kinase
H0I32_RS09640	COG0463	Glycosyl transferase, family 2
H0I32_RS09655	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H0I32_RS09660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0I32_RS09675	COG2315	Protein conserved in bacteria
H0I32_RS09680	COG0784	Response regulator, receiver
H0I32_RS09690	COG4251	negative regulation of phosphorylation
H0I32_RS09700	COG5002	protein histidine kinase activity
H0I32_RS09710	COG3279	Response regulator of the LytR AlgR family
H0I32_RS09755	COG0745	RESPONSE REGULATOR receiver
H0I32_RS09765	COG1482	cell wall glycoprotein biosynthetic process
H0I32_RS09770	COG2824	Alkylphosphonate utilization operon protein PhnA
H0I32_RS09810	COG2814	Major facilitator Superfamily
H0I32_RS09820	COG0235	Class ii aldolase
H0I32_RS09825	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
H0I32_RS09835	COG1454	alcohol dehydrogenase
H0I32_RS09840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H0I32_RS09845	COG0366	Alpha amylase catalytic
H0I32_RS09855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0I32_RS09860	COG4206	TonB-dependent receptor
H0I32_RS09860	COG1629	transport
H0I32_RS09875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0I32_RS09880	COG1554	hydrolase, family 65, central catalytic
H0I32_RS09885	COG1501	Belongs to the glycosyl hydrolase 31 family
H0I32_RS09895	COG0366	Alpha amylase catalytic
H0I32_RS09900	COG1082	Xylose isomerase domain protein TIM barrel
H0I32_RS09915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0I32_RS09935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0I32_RS09955	COG2081	HI0933 family
H0I32_RS09985	COG1187	pseudouridine synthase activity
H0I32_RS09995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H0I32_RS10000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0I32_RS10005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H0I32_RS10010	COG1349	DNA-binding transcription factor activity
H0I32_RS10040	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H0I32_RS10050	COG1166	arginine decarboxylase activity
H0I32_RS10055	COG0010	Belongs to the arginase family
H0I32_RS10060	COG1899	peptidyl-lysine modification to peptidyl-hypusine
H0I32_RS10065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0I32_RS10065	COG3153	acetyltransferase
H0I32_RS10095	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS10110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0I32_RS10145	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H0I32_RS10175	COG1629	transport
H0I32_RS10175	COG4206	TonB-dependent receptor
H0I32_RS10195	COG0590	tRNA wobble adenosine to inosine editing
H0I32_RS10210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0I32_RS10230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0I32_RS10235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H0I32_RS10240	COG0066	3-isopropylmalate dehydratase activity
H0I32_RS10255	COG0004	ammonium transporteR
H0I32_RS10265	COG0069	glutamate synthase activity
H0I32_RS10265	COG0070	glutamate synthase
H0I32_RS10265	COG0067	glutamate synthase
H0I32_RS10275	COG0165	Argininosuccinate lyase
H0I32_RS10285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H0I32_RS10295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0I32_RS10305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H0I32_RS10310	COG0137	argininosuccinate synthase activity
H0I32_RS10320	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS10325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0I32_RS10330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H0I32_RS10340	COG0028	Belongs to the TPP enzyme family
H0I32_RS10345	COG0129	dihydroxy-acid dehydratase activity
H0I32_RS10355	COG4771	TonB-dependent receptor
H0I32_RS10395	COG0477	Major facilitator Superfamily
H0I32_RS10395	COG2814	Major facilitator Superfamily
H0I32_RS10405	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H0I32_RS10435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0I32_RS10450	COG0823	Involved in the tonB-independent uptake of proteins
H0I32_RS10450	COG1506	peptidase
H0I32_RS10470	COG0658	competence protein
H0I32_RS10470	COG2333	competence protein COMEC
H0I32_RS10475	COG0791	NLP P60 protein
H0I32_RS10480	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS10485	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0I32_RS10490	COG0793	Belongs to the peptidase S41A family
H0I32_RS10495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0I32_RS10500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H0I32_RS10510	COG2001	Belongs to the MraZ family
H0I32_RS10515	COG0275	rRNA processing
H0I32_RS10530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0I32_RS10535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0I32_RS10540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H0I32_RS10545	COG0772	Belongs to the SEDS family
H0I32_RS10550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H0I32_RS10555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0I32_RS10570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0I32_RS10575	COG1610	YqeY-like protein
H0I32_RS10630	COG5002	protein histidine kinase activity
H0I32_RS10635	COG0745	RESPONSE REGULATOR receiver
H0I32_RS10645	COG1428	Deoxynucleoside kinase
H0I32_RS10695	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H0I32_RS10700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0I32_RS10705	COG1045	serine acetyltransferase
H0I32_RS10720	COG0022	dehydrogenase e1 component
H0I32_RS10720	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0I32_RS10725	COG2086	electron transfer activity
H0I32_RS10730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H0I32_RS10740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H0I32_RS10745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H0I32_RS10755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H0I32_RS10760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0I32_RS10765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H0I32_RS10770	COG1959	2 iron, 2 sulfur cluster binding
H0I32_RS10780	COG0175	sulfate reduction
H0I32_RS10785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0I32_RS10795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0I32_RS10795	COG1648	precorrin-2 dehydrogenase activity
H0I32_RS10800	COG0492	ferredoxin-NADP+ reductase activity
H0I32_RS10815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0I32_RS10820	COG0280	phosphate acetyltransferase
H0I32_RS10820	COG0857	belongs to the CobB CobQ family
H0I32_RS10825	COG1131	(ABC) transporter
H0I32_RS10835	COG0436	Aminotransferase
H0I32_RS10840	COG0287	Prephenate dehydrogenase
H0I32_RS10845	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H0I32_RS10850	COG1162	GTPase activity
H0I32_RS10855	COG1490	D-aminoacyl-tRNA deacylase activity
H0I32_RS10880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0I32_RS10885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H0I32_RS10890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H0I32_RS10925	COG2076	Multidrug Resistance protein
H0I32_RS10930	COG0358	DNA primase activity
H0I32_RS10935	COG2197	response regulator
H0I32_RS10940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0I32_RS10975	COG1309	transcriptional regulator
H0I32_RS10980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0I32_RS10985	COG3396	Phenylacetate-CoA oxygenase
H0I32_RS10990	COG3460	Phenylacetate-CoA oxygenase
H0I32_RS10995	COG3396	Phenylacetate-CoA oxygenase
H0I32_RS11000	COG2151	metal-sulfur cluster biosynthetic enzyme
H0I32_RS11005	COG1024	Enoyl-CoA hydratase
H0I32_RS11010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0I32_RS11015	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0I32_RS11025	COG2321	neutral zinc metallopeptidase
H0I32_RS11030	COG0183	Belongs to the thiolase family
H0I32_RS11035	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS11035	COG2030	dehydratase
H0I32_RS11055	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0I32_RS11060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0I32_RS11065	COG0022	dehydrogenase e1 component
H0I32_RS11075	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H0I32_RS11085	COG0351	phosphomethylpyrimidine kinase
H0I32_RS11090	COG0352	thiamine-phosphate diphosphorylase activity
H0I32_RS11095	COG2022	thiamine diphosphate biosynthetic process
H0I32_RS11100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H0I32_RS11110	COG1278	Cold shock
H0I32_RS11115	COG0659	secondary active sulfate transmembrane transporter activity
H0I32_RS11125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H0I32_RS11135	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0I32_RS11145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H0I32_RS11165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H0I32_RS11170	COG0401	homolog of Blt101
H0I32_RS11180	COG0321	lipoyl(octanoyl) transferase activity
H0I32_RS11200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0I32_RS11205	COG1629	transport
H0I32_RS11230	COG1404	Belongs to the peptidase S8 family
H0I32_RS11265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0I32_RS11270	COG1960	acyl-CoA dehydrogenase activity
H0I32_RS11275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0I32_RS11290	COG0811	peptide transport
H0I32_RS11295	COG0848	biopolymer transport protein
H0I32_RS11305	COG0285	dihydrofolate synthase activity
H0I32_RS11320	COG2234	aminopeptidase activity
H0I32_RS11325	COG2234	aminopeptidase activity
H0I32_RS11325	COG4935	Belongs to the peptidase S8 family
H0I32_RS11345	COG0671	phosphoesterase, PA-phosphatase related
H0I32_RS11350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0I32_RS11355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0I32_RS11370	COG0295	cytidine deaminase activity
H0I32_RS11375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0I32_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS11395	COG0789	Transcriptional regulator
H0I32_RS11400	COG0484	heat shock protein binding
H0I32_RS11420	COG1127	ABC transporter
H0I32_RS11425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0I32_RS11430	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
H0I32_RS11440	COG1216	Glycosyl transferase, family 2
H0I32_RS11450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0I32_RS11455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H0I32_RS11455	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H0I32_RS11495	COG1510	regulation of RNA biosynthetic process
H0I32_RS11505	COG0339	signal peptide processing
H0I32_RS11515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H0I32_RS11520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0I32_RS11525	COG0563	adenylate kinase activity
H0I32_RS11530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H0I32_RS11535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0I32_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS11595	COG2003	Belongs to the UPF0758 family
H0I32_RS11605	COG1011	Hydrolase
H0I32_RS11615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0I32_RS11635	COG1629	transport
H0I32_RS11640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0I32_RS11655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H0I32_RS11660	COG0049	tRNA binding
H0I32_RS11665	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H0I32_RS11670	COG0051	transcription antitermination factor activity, RNA binding
H0I32_RS11675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H0I32_RS11680	COG0088	Forms part of the polypeptide exit tunnel
H0I32_RS11685	COG0089	rRNA binding
H0I32_RS11690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H0I32_RS11695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H0I32_RS11700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H0I32_RS11705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H0I32_RS11710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H0I32_RS11715	COG0255	Belongs to the universal ribosomal protein uL29 family
H0I32_RS11720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H0I32_RS11725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H0I32_RS11730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H0I32_RS11735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H0I32_RS11740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H0I32_RS11745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H0I32_RS11750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H0I32_RS11755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H0I32_RS11760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H0I32_RS11765	COG1841	ribosomal large subunit assembly
H0I32_RS11770	COG0200	Binds to the 23S rRNA
H0I32_RS11780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H0I32_RS11785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H0I32_RS11790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H0I32_RS11795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H0I32_RS11800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H0I32_RS11805	COG0202	RNA polymerase activity
H0I32_RS11810	COG0203	ribosomal protein L17
H0I32_RS11820	COG0148	phosphopyruvate hydratase activity
H0I32_RS11840	COG0688	phosphatidylethanolamine metabolic process
H0I32_RS11855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0I32_RS11860	COG0799	negative regulation of ribosome biogenesis
H0I32_RS11875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H0I32_RS11895	COG0189	ligase activity
H0I32_RS11915	COG5002	protein histidine kinase activity
H0I32_RS11920	COG0018	arginyl-trna synthetase
H0I32_RS11950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0I32_RS11955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H0I32_RS11960	COG1187	pseudouridine synthase activity
H0I32_RS11970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H0I32_RS11970	COG0662	Cupin 2, conserved barrel domain protein
H0I32_RS11980	COG0433	COG0433 Predicted ATPase
H0I32_RS11985	COG0602	queuosine metabolic process
H0I32_RS12000	COG0367	asparagine synthase
H0I32_RS12015	COG0187	DNA topoisomerase II activity
H0I32_RS12035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0I32_RS12045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H0I32_RS12050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H0I32_RS12055	COG0215	cysteine-tRNA ligase activity
H0I32_RS12060	COG0302	gtp cyclohydrolase
H0I32_RS12085	COG0442	prolyl-tRNA aminoacylation
H0I32_RS12095	COG0268	Binds directly to 16S ribosomal RNA
H0I32_RS12100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0I32_RS12125	COG0791	NLP P60 protein
H0I32_RS12125	COG1388	LysM domain
H0I32_RS12130	COG1160	GTP binding
H0I32_RS12160	COG0789	Transcriptional regulator
H0I32_RS12160	COG4978	Transcriptional regulator
H0I32_RS12170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H0I32_RS12180	COG2273	Hydrolase Family 16
H0I32_RS12180	COG5297	Belongs to the glycosyl hydrolase family 6
H0I32_RS12185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H0I32_RS12190	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0I32_RS12200	COG0564	pseudouridine synthase activity
H0I32_RS12205	COG3022	response to hydroperoxide
H0I32_RS12220	COG4771	TonB-dependent receptor
H0I32_RS12245	COG0513	Belongs to the DEAD box helicase family
H0I32_RS12255	COG4628	conserved protein (DUF2132)
H0I32_RS12260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0I32_RS12275	COG0159	tryptophan synthase activity
H0I32_RS12300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS12310	COG1538	Outer membrane efflux protein
H0I32_RS12325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0I32_RS12330	COG1733	regulation of RNA biosynthetic process
H0I32_RS12365	COG0753	catalase activity
H0I32_RS12380	COG1280	lysine exporter protein (LysE YggA)
H0I32_RS12385	COG0583	DNA-binding transcription factor activity
H0I32_RS12400	COG0640	Transcriptional regulator
H0I32_RS12425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0I32_RS12440	COG4585	Histidine kinase
H0I32_RS12445	COG2197	response regulator
H0I32_RS12460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H0I32_RS12465	COG0484	heat shock protein binding
H0I32_RS12470	COG4152	abc transporter atp-binding protein
H0I32_RS12475	COG1668	transmembrane transport
H0I32_RS12480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H0I32_RS12480	COG3264	Mechanosensitive ion channel
H0I32_RS12495	COG2326	polyphosphate kinase activity
H0I32_RS12510	COG0019	diaminopimelate decarboxylase activity
H0I32_RS12520	COG0045	succinate-CoA ligase (ADP-forming) activity
H0I32_RS12545	COG0556	nucleotide-excision repair
H0I32_RS12590	COG1131	(ABC) transporter
H0I32_RS12605	COG1612	heme a metabolic process
H0I32_RS12615	COG0517	IMP dehydrogenase activity
H0I32_RS12615	COG0617	tRNA 3'-terminal CCA addition
H0I32_RS12615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H0I32_RS12670	COG0463	Glycosyl transferase, family 2
H0I32_RS12675	COG0463	Glycosyl transferase, family 2
H0I32_RS12680	COG1216	Glycosyl transferase, family 2
H0I32_RS12680	COG0463	Glycosyl transferase, family 2
H0I32_RS12690	COG2171	N-acyltransferase activity
H0I32_RS12695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0I32_RS12700	COG0242	peptide deformylase activity
H0I32_RS12710	COG3956	TIGRFAM MazG family protein
H0I32_RS12725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H0I32_RS12745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0I32_RS12755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0I32_RS12765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0I32_RS12770	COG5658	integral membrane protein
H0I32_RS12775	COG0300	oxidoreductase activity
H0I32_RS12785	COG0501	Belongs to the peptidase M48B family
H0I32_RS12790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0I32_RS12815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H0I32_RS12825	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0I32_RS12830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0I32_RS12840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H0I32_RS12850	COG0105	UTP biosynthetic process
H0I32_RS12855	COG4206	TonB-dependent receptor
H0I32_RS12885	COG2032	superoxide dismutase activity
H0I32_RS12895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0I32_RS12900	COG0589	response to stress
H0I32_RS12955	COG0513	Belongs to the DEAD box helicase family
H0I32_RS12960	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H0I32_RS12975	COG4206	TonB-dependent receptor
H0I32_RS12975	COG1629	transport
H0I32_RS12985	COG0326	Molecular chaperone. Has ATPase activity
H0I32_RS12990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0I32_RS13000	COG1482	cell wall glycoprotein biosynthetic process
H0I32_RS13030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0I32_RS13040	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0I32_RS13045	COG1342	Belongs to the UPF0251 family
H0I32_RS13055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0I32_RS13055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0I32_RS13070	COG5002	protein histidine kinase activity
H0I32_RS13070	COG2198	Histidine kinase
H0I32_RS13070	COG0784	Response regulator, receiver
H0I32_RS13075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0I32_RS13080	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0I32_RS13090	COG1546	Belongs to the CinA family
H0I32_RS13090	COG1058	Belongs to the CinA family
H0I32_RS13095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H0I32_RS13100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H0I32_RS13110	COG0552	protein localization to endoplasmic reticulum
H0I32_RS13125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H0I32_RS13130	COG0612	Peptidase, M16
H0I32_RS13140	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H0I32_RS13145	COG0076	glutamate decarboxylase activity
H0I32_RS13150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0I32_RS13150	COG0519	Catalyzes the synthesis of GMP from XMP
H0I32_RS13170	COG0504	CTP synthase activity
H0I32_RS13175	COG0706	membrane insertase activity
H0I32_RS13185	COG0482	sulfurtransferase activity
H0I32_RS13200	COG3263	regulation of cellular component size
H0I32_RS13220	COG0534	Mate efflux family protein
H0I32_RS13230	COG0671	phosphoesterase, PA-phosphatase related
H0I32_RS13240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0I32_RS13240	COG3952	Lipid A Biosynthesis
H0I32_RS13245	COG0463	Glycosyl transferase, family 2
H0I32_RS13270	COG0823	Involved in the tonB-independent uptake of proteins
H0I32_RS13270	COG1506	peptidase
H0I32_RS13275	COG2827	Endonuclease containing a URI domain
H0I32_RS13285	COG0653	protein targeting
H0I32_RS13300	COG1136	(ABC) transporter
H0I32_RS13310	COG0488	(ABC) transporter
H0I32_RS13320	COG3206	protein involved in exopolysaccharide biosynthesis
H0I32_RS13320	COG0489	protein tyrosine kinase activity
H0I32_RS13325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0I32_RS13330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0I32_RS13370	COG0457	Tetratricopeptide repeat
H0I32_RS13385	COG0463	Glycosyl transferase, family 2
H0I32_RS13395	COG1215	transferase activity, transferring glycosyl groups
H0I32_RS13400	COG0438	transferase activity, transferring glycosyl groups
H0I32_RS13435	COG1696	Membrane protein involved in D-alanine export
H0I32_RS13455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0I32_RS13470	COG0438	transferase activity, transferring glycosyl groups
H0I32_RS13475	COG0463	Glycosyl transferase, family 2
H0I32_RS13505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0I32_RS13520	COG1183	phosphatidylcholine synthase activity
H0I32_RS13525	COG2354	Protein conserved in bacteria
H0I32_RS13535	COG1137	ATPase activity
H0I32_RS13545	COG0805	protein transport
H0I32_RS13550	COG0517	IMP dehydrogenase activity
H0I32_RS13550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0I32_RS13555	COG0514	ATP-dependent DNA helicase (RecQ)
H0I32_RS13565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0I32_RS13570	COG0693	protein deglycase activity
H0I32_RS13580	COG1607	acyl-coa hydrolase
H0I32_RS13595	COG1322	Protein conserved in bacteria
H0I32_RS13600	COG1120	ATPase activity
H0I32_RS13605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0I32_RS13670	COG0564	pseudouridine synthase activity
H0I32_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
H0I32_RS13705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0I32_RS13725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H0I32_RS13740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H0I32_RS13750	COG1295	ribonuclease BN
H0I32_RS13760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0I32_RS13765	COG3279	Response regulator of the LytR AlgR family
H0I32_RS13770	COG0360	Binds together with S18 to 16S ribosomal RNA
H0I32_RS13775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H0I32_RS13780	COG0359	binds to the 23S rRNA
H0I32_RS13785	COG0584	glycerophosphoryl diester phosphodiesterase
H0I32_RS13795	COG1136	(ABC) transporter
H0I32_RS13795	COG0577	efflux transmembrane transporter activity
H0I32_RS13800	COG0124	histidyl-tRNA synthetase
H0I32_RS13825	COG3275	phosphorelay sensor kinase activity
H0I32_RS13830	COG3279	Response regulator of the LytR AlgR family
H0I32_RS13835	COG0471	metal ion transport
H0I32_RS13840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H0I32_RS13845	COG4585	Histidine kinase
H0I32_RS13920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H0I32_RS13930	COG0732	type I restriction modification DNA specificity domain
H0I32_RS13940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H0I32_RS13995	COG1858	cytochrome C peroxidase
H0I32_RS14025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0I32_RS14030	COG1678	Uncharacterized ACR, COG1678
H0I32_RS14035	COG0776	regulation of translation
H0I32_RS14040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H0I32_RS14045	COG0514	ATP-dependent DNA helicase (RecQ)
H0I32_RS14065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0I32_RS14070	COG0415	Belongs to the DNA photolyase family
H0I32_RS14085	COG0386	Belongs to the glutathione peroxidase family
H0I32_RS14095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H0I32_RS14120	COG0335	large ribosomal subunit rRNA binding
H0I32_RS14130	COG0336	Belongs to the RNA methyltransferase TrmD family
H0I32_RS14135	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H0I32_RS14150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0I32_RS14155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H0I32_RS14165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0I32_RS14180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H0I32_RS14185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0I32_RS14190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H0I32_RS14195	COG0824	Thioesterase
H0I32_RS14200	COG1739	Uncharacterized protein family UPF0029
H0I32_RS14210	COG1011	Hydrolase
H0I32_RS14215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0I32_RS14215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0I32_RS14230	COG2890	protein-(glutamine-N5) methyltransferase activity
H0I32_RS14235	COG1611	Belongs to the LOG family
H0I32_RS14240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H0I32_RS14250	COG0737	Belongs to the 5'-nucleotidase family
H0I32_RS14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0I32_RS14290	COG0497	DNA recombination
H0I32_RS14300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H0I32_RS14325	COG2226	methyltransferase
H0I32_RS14330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H0I32_RS14330	COG0116	Belongs to the methyltransferase superfamily
H0I32_RS14340	COG2326	polyphosphate kinase activity
H0I32_RS14345	COG2326	polyphosphate kinase activity
H0I32_RS14360	COG1611	Belongs to the LOG family
H0I32_RS14370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0I32_RS14380	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H0I32_RS14430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0I32_RS14440	COG1560	Kdo2-lipid A biosynthetic process
H0I32_RS14455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS14465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H0I32_RS14545	COG2217	Heavy metal translocating P-type atpase
H0I32_RS14620	COG1234	tRNA 3'-trailer cleavage
H0I32_RS14650	COG3279	Response regulator of the LytR AlgR family
H0I32_RS14720	COG0745	RESPONSE REGULATOR receiver
H0I32_RS14720	COG2972	Histidine kinase
H0I32_RS14725	COG3279	Response regulator of the LytR AlgR family
H0I32_RS14810	COG2197	response regulator
H0I32_RS14845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0I32_RS14865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0I32_RS15065	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
H0I32_RS15070	COG1691	(AIR) carboxylase
H0I32_RS15075	COG1606	tRNA processing
H0I32_RS15090	COG3273	potassium ion transport
H0I32_RS15090	COG0471	metal ion transport
H0I32_RS15120	COG1271	oxidase subunit
H0I32_RS15125	COG1294	oxidase, subunit
H0I32_RS15145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H0I32_RS15150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0I32_RS15155	COG1335	isochorismatase
H0I32_RS15165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS15185	COG3540	Alkaline phosphatase
H0I32_RS15195	COG0592	DNA-directed DNA polymerase activity
H0I32_RS15225	COG1702	phosphate starvation-inducible protein PhoH
H0I32_RS15235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H0I32_RS15260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0I32_RS15290	COG1104	cysteine desulfurase activity
H0I32_RS15320	COG1418	mRNA catabolic process
H0I32_RS15330	COG4974	Belongs to the 'phage' integrase family
H0I32_RS15355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0I32_RS15360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0I32_RS15365	COG0297	glycogen (starch) synthase activity
H0I32_RS15370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H0I32_RS15375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H0I32_RS15410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H0I32_RS15410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H0I32_RS15415	COG0791	NLP P60 protein
H0I32_RS15420	COG0183	Belongs to the thiolase family
H0I32_RS15425	COG1480	7TM receptor with intracellular HD hydrolase
H0I32_RS15435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0I32_RS15440	COG3119	arylsulfatase activity
H0I32_RS15445	COG3119	arylsulfatase activity
H0I32_RS15450	COG3119	arylsulfatase activity
H0I32_RS15480	COG3119	arylsulfatase activity
H0I32_RS15485	COG3119	arylsulfatase activity
H0I32_RS15490	COG3119	arylsulfatase activity
H0I32_RS15500	COG3119	arylsulfatase activity
H0I32_RS15510	COG3119	arylsulfatase activity
H0I32_RS15515	COG3119	arylsulfatase activity
H0I32_RS15525	COG3119	arylsulfatase activity
H0I32_RS15560	COG3119	arylsulfatase activity
H0I32_RS15570	COG3408	Glycogen debranching enzyme
H0I32_RS15570	COG3119	arylsulfatase activity
H0I32_RS15575	COG3119	arylsulfatase activity
H0I32_RS15585	COG3119	arylsulfatase activity
H0I32_RS15605	COG3119	arylsulfatase activity
H0I32_RS15615	COG2205	protein histidine kinase activity
H0I32_RS15615	COG3292	Two component regulator propeller
H0I32_RS15615	COG0745	RESPONSE REGULATOR receiver
H0I32_RS15620	COG1012	belongs to the aldehyde dehydrogenase family
H0I32_RS15625	COG0738	Major facilitator superfamily
H0I32_RS15630	COG0247	lactate metabolic process
H0I32_RS15635	COG1139	Iron-sulfur cluster binding protein
H0I32_RS15640	COG1556	Lactate utilization protein
H0I32_RS15670	COG0628	permease
H0I32_RS15695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H0I32_RS15705	COG0205	6-phosphofructokinase activity
H0I32_RS15720	COG1803	Methylglyoxal synthase
H0I32_RS15740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0I32_RS15755	COG0488	(ABC) transporter
H0I32_RS15820	COG0714	Associated with various cellular activities
H0I32_RS15865	COG1022	Amp-dependent synthetase and ligase
H0I32_RS15870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H0I32_RS15880	COG2801	Transposase and inactivated derivatives
H0I32_RS15895	COG3177	Filamentation induced by cAMP protein fic
H0I32_RS15990	COG3047	cAMP biosynthetic process
H0I32_RS15990	COG2885	chlorophyll binding
H0I32_RS16015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS16055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS16125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H0I32_RS16310	COG3609	addiction module antidote protein, CC2985 family
H0I32_RS16410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0I32_RS16420	COG3634	alkyl hydroperoxide reductase activity
H0I32_RS16500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H0I32_RS16680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0I32_RS16720	COG2885	chlorophyll binding
H0I32_RS16720	COG3047	cAMP biosynthetic process
H0I32_RS16735	COG1695	Transcriptional regulator
H0I32_RS16880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS16900	COG4771	TonB-dependent receptor
H0I32_RS16925	COG4974	Belongs to the 'phage' integrase family
H0I32_RS16930	COG0217	transcriptional regulatory protein
H0I32_RS16940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H0I32_RS16975	COG0277	FAD linked oxidase domain protein
H0I32_RS16975	COG0247	lactate metabolic process
H0I32_RS16985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H0I32_RS16990	COG1301	dicarboxylic acid transport
H0I32_RS17015	COG0302	gtp cyclohydrolase
H0I32_RS17030	COG3046	protein related to deoxyribodipyrimidine photolyase
H0I32_RS17045	COG0702	epimerase
H0I32_RS17065	COG0798	PFAM Bile acid sodium symporter
H0I32_RS17090	COG0673	inositol 2-dehydrogenase activity
H0I32_RS17105	COG0598	Magnesium transport protein CorA
H0I32_RS17120	COG0424	maF-like protein
H0I32_RS17130	COG0561	phosphatase activity
H0I32_RS17155	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H0I32_RS17170	COG0429	hydrolase of the alpha beta-hydrolase fold
H0I32_RS17200	COG0606	chelatase, subunit chli
H0I32_RS17225	COG0564	pseudouridine synthase activity
H0I32_RS17235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H0I32_RS17255	COG1760	l-serine dehydratase
H0I32_RS17270	COG0443	Heat shock 70 kDa protein
H0I32_RS17295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H0I32_RS17300	COG2070	2-Nitropropane dioxygenase
H0I32_RS17305	COG4191	Histidine kinase
H0I32_RS17310	COG3279	Response regulator of the LytR AlgR family
H0I32_RS17330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H0I32_RS17340	COG2996	Protein conserved in bacteria
H0I32_RS17355	COG1575	Belongs to the MenA family. Type 1 subfamily
H0I32_RS17360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H0I32_RS17370	COG4948	Mandelate Racemase Muconate Lactonizing
H0I32_RS17385	COG2304	oxidoreductase activity
H0I32_RS17440	COG0463	Glycosyl transferase, family 2
H0I32_RS17440	COG1216	Glycosyl transferase, family 2
H0I32_RS17450	COG0237	dephospho-CoA kinase activity
H0I32_RS17465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H0I32_RS17470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0I32_RS17480	COG2176	DNA-directed DNA polymerase activity
H0I32_RS17495	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0I32_RS17500	COG0673	inositol 2-dehydrogenase activity
H0I32_RS17505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0I32_RS17530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H0I32_RS17545	COG0813	purine-nucleoside phosphorylase activity
H0I32_RS17550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H0I32_RS17560	COG0542	response to heat
H0I32_RS17575	COG0564	pseudouridine synthase activity
H0I32_RS17585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H0I32_RS17600	COG1506	peptidase
H0I32_RS17600	COG0823	Involved in the tonB-independent uptake of proteins
H0I32_RS17600	COG4946	Tricorn protease homolog
H0I32_RS17630	COG0300	oxidoreductase activity
H0I32_RS17635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0I32_RS17645	COG0488	(ABC) transporter
H0I32_RS17655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H0I32_RS17665	COG1119	ATPase activity
H0I32_RS17670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0I32_RS17685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0I32_RS17695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0I32_RS17740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0I32_RS17815	COG1595	DNA-templated transcription, initiation
H0I32_RS17890	COG0450	alkyl hydroperoxide reductase
H0I32_RS17895	COG1757	Na H antiporter
H0I32_RS17905	COG1522	sequence-specific DNA binding
H0I32_RS17915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0I32_RS17920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0I32_RS17925	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0I32_RS17965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0I32_RS17970	COG2217	Heavy metal translocating P-type atpase
H0I32_RS17990	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0I32_RS18015	COG0038	chloride channel
H0I32_RS18040	COG0246	Mannitol dehydrogenase
H0I32_RS18045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0I32_RS18080	COG0408	coproporphyrinogen oxidase activity