locus-tag	class	description
BA177_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BA177_RS00010	COG0594	ribonuclease P activity
BA177_RS00015	COG0706	membrane insertase activity
BA177_RS00020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BA177_RS00030	COG4555	ABC transporter
BA177_RS00040	COG0445	tRNA wobble uridine modification
BA177_RS00045	COG4166	transmembrane transport
BA177_RS00050	COG0601	transmembrane transport
BA177_RS00055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA177_RS00080	COG0604	alcohol dehydrogenase
BA177_RS00085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA177_RS00090	COG0372	Belongs to the citrate synthase family
BA177_RS00105	COG0357	Ribosomal RNA small subunit methyltransferase G
BA177_RS00110	COG1192	Involved in chromosome partitioning
BA177_RS00115	COG1475	DNA binding
BA177_RS00125	COG3300	MHYT domain
BA177_RS00125	COG5001	Diguanylate cyclase
BA177_RS00135	COG0356	it plays a direct role in the translocation of protons across the membrane
BA177_RS00150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BA177_RS00155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BA177_RS00160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BA177_RS00165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BA177_RS00170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BA177_RS00185	COG0251	oxidation-reduction process
BA177_RS00190	COG2423	ornithine cyclodeaminase activity
BA177_RS00250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BA177_RS00265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BA177_RS00285	COG4269	membrane
BA177_RS00305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BA177_RS00310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA177_RS00340	COG1280	lysine exporter protein (LysE YggA)
BA177_RS00355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA177_RS00380	COG0625	glutathione transferase activity
BA177_RS00400	COG0339	signal peptide processing
BA177_RS00405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA177_RS00410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BA177_RS00435	COG0519	Catalyzes the synthesis of GMP from XMP
BA177_RS00440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA177_RS00445	COG1404	Belongs to the peptidase S8 family
BA177_RS00460	COG0009	L-threonylcarbamoyladenylate synthase
BA177_RS00470	COG2922	Belongs to the Smg family
BA177_RS00475	COG0758	DNA mediated transformation
BA177_RS00480	COG1652	LysM domain
BA177_RS00495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA177_RS00495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA177_RS00505	COG5000	phosphorelay sensor kinase activity
BA177_RS00510	COG2204	response regulator
BA177_RS00525	COG0018	arginyl-trna synthetase
BA177_RS00530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA177_RS00560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BA177_RS00575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA177_RS00575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA177_RS00585	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BA177_RS00600	COG1115	amino acid carrier protein
BA177_RS00630	COG0070	glutamate synthase
BA177_RS00630	COG0069	glutamate synthase activity
BA177_RS00630	COG0067	glutamate synthase
BA177_RS00635	COG0493	'glutamate synthase
BA177_RS00645	COG0642	Histidine kinase
BA177_RS00650	COG0745	RESPONSE REGULATOR receiver
BA177_RS00670	COG0534	Mate efflux family protein
BA177_RS00675	COG0534	Mate efflux family protein
BA177_RS00680	COG1960	acyl-CoA dehydrogenase activity
BA177_RS00690	COG2885	chlorophyll binding
BA177_RS00710	COG2177	Part of the ABC transporter FtsEX involved in
BA177_RS00715	COG2884	Cell division ATP-binding protein ftsE
BA177_RS00720	COG0552	protein localization to endoplasmic reticulum
BA177_RS00725	COG0742	ribosomal rna small subunit methyltransferase
BA177_RS00730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BA177_RS00735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BA177_RS00745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BA177_RS00750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BA177_RS00755	COG2003	Belongs to the UPF0758 family
BA177_RS00760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA177_RS00765	COG0756	dUTP diphosphatase activity
BA177_RS00775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BA177_RS00780	COG0708	Exodeoxyribonuclease III
BA177_RS00785	COG2271	Major facilitator Superfamily
BA177_RS00800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BA177_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BA177_RS00825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BA177_RS00830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BA177_RS00870	COG0181	hydroxymethylbilane synthase activity
BA177_RS00880	COG3275	phosphorelay sensor kinase activity
BA177_RS00890	COG0004	ammonium transporteR
BA177_RS00895	COG0347	Belongs to the P(II) protein family
BA177_RS00915	COG0668	transmembrane transport
BA177_RS00925	COG2423	ornithine cyclodeaminase activity
BA177_RS00935	COG3245	cytochrome
BA177_RS00975	COG1196	nuclear chromosome segregation
BA177_RS01045	COG2003	Belongs to the UPF0758 family
BA177_RS01055	COG1230	cation diffusion facilitator family transporter
BA177_RS01085	COG0640	Transcriptional regulator
BA177_RS01095	COG4771	TonB-dependent receptor
BA177_RS01140	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS01160	COG2132	Multicopper oxidase
BA177_RS01175	COG2217	Heavy metal translocating P-type atpase
BA177_RS01180	COG0531	amino acid
BA177_RS01185	COG2226	methyltransferase
BA177_RS01300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA177_RS01300	COG0616	signal peptide processing
BA177_RS01345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BA177_RS01415	COG3550	peptidyl-serine autophosphorylation
BA177_RS01430	COG3550	peptidyl-serine autophosphorylation
BA177_RS01445	COG0823	Involved in the tonB-independent uptake of proteins
BA177_RS01445	COG1506	peptidase
BA177_RS01485	COG2801	Transposase and inactivated derivatives
BA177_RS01495	COG5265	(ABC) transporter
BA177_RS01515	COG2771	luxR family
BA177_RS01530	COG2856	Zn peptidase
BA177_RS01545	COG1181	Belongs to the D-alanine--D-alanine ligase family
BA177_RS01555	COG3047	cAMP biosynthetic process
BA177_RS01555	COG2885	chlorophyll binding
BA177_RS01560	COG0471	metal ion transport
BA177_RS01560	COG3273	potassium ion transport
BA177_RS01565	COG4771	TonB-dependent receptor
BA177_RS01580	COG4771	TonB-dependent receptor
BA177_RS01605	COG0659	secondary active sulfate transmembrane transporter activity
BA177_RS01615	COG1757	Na H antiporter
BA177_RS01630	COG0457	Tetratricopeptide repeat
BA177_RS01640	COG0457	Tetratricopeptide repeat
BA177_RS01660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BA177_RS01665	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BA177_RS01670	COG0174	glutamine synthetase
BA177_RS01710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS01715	COG0789	Transcriptional regulator
BA177_RS01720	COG2217	Heavy metal translocating P-type atpase
BA177_RS01735	COG1414	Transcriptional regulator
BA177_RS01740	COG0800	Aldolase
BA177_RS01750	COG1595	DNA-templated transcription, initiation
BA177_RS01770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS01780	COG0733	neurotransmitter:sodium symporter activity
BA177_RS01790	COG3023	N-Acetylmuramoyl-L-alanine amidase
BA177_RS01810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA177_RS01815	COG0363	glucosamine-6-phosphate deaminase activity
BA177_RS01820	COG3876	Protein conserved in bacteria
BA177_RS01825	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BA177_RS01835	COG2807	transmembrane transport
BA177_RS01840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA177_RS01855	COG0577	efflux transmembrane transporter activity
BA177_RS01860	COG1136	(ABC) transporter
BA177_RS01880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BA177_RS01885	COG0363	glucosamine-6-phosphate deaminase activity
BA177_RS01895	COG0837	glucose binding
BA177_RS01910	COG4771	TonB-dependent receptor
BA177_RS01925	COG0457	Tetratricopeptide repeat
BA177_RS01930	COG4771	TonB-dependent receptor
BA177_RS01945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA177_RS01950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS01970	COG0022	dehydrogenase e1 component
BA177_RS01980	COG1285	pathogenesis
BA177_RS02005	COG4638	Rieske (2fe-2S)
BA177_RS02010	COG1177	transmembrane transport
BA177_RS02015	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA177_RS02020	COG3842	ATPase activity
BA177_RS02025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA177_RS02030	COG1960	acyl-CoA dehydrogenase activity
BA177_RS02035	COG1309	transcriptional regulator
BA177_RS02040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA177_RS02055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BA177_RS02065	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS02085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA177_RS02100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA177_RS02110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BA177_RS02125	COG0165	Argininosuccinate lyase
BA177_RS02130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BA177_RS02135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BA177_RS02140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA177_RS02145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BA177_RS02155	COG0137	argininosuccinate synthase activity
BA177_RS02160	COG1438	arginine binding
BA177_RS02185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS02190	COG1115	amino acid carrier protein
BA177_RS02200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA177_RS02205	COG1228	amidohydrolase
BA177_RS02210	COG1228	amidohydrolase
BA177_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA177_RS02235	COG1131	(ABC) transporter
BA177_RS02240	COG0842	Transport permease protein
BA177_RS02245	COG2135	peptidase activity
BA177_RS02250	COG1461	Dihydroxyacetone kinase
BA177_RS02260	COG3267	Type II secretory pathway component ExeA
BA177_RS02260	COG3409	Peptidoglycan-binding domain 1 protein
BA177_RS02265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA177_RS02270	COG0142	geranyltranstransferase activity
BA177_RS02290	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BA177_RS02295	COG3425	synthase
BA177_RS02310	COG0039	L-malate dehydrogenase activity
BA177_RS02320	COG1595	DNA-templated transcription, initiation
BA177_RS02335	COG1131	(ABC) transporter
BA177_RS02345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BA177_RS02350	COG1842	Phage shock protein A
BA177_RS02365	COG1983	PspC domain protein
BA177_RS02395	COG2918	glutathione biosynthetic process
BA177_RS02420	COG0490	domain, Protein
BA177_RS02420	COG0471	metal ion transport
BA177_RS02430	COG0210	DNA helicase
BA177_RS02450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BA177_RS02455	COG0612	Peptidase, M16
BA177_RS02460	COG0596	Alpha beta hydrolase
BA177_RS02465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BA177_RS02475	COG0674	pyruvate-flavodoxin oxidoreductase activity
BA177_RS02475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BA177_RS02480	COG1013	pyruvate-flavodoxin oxidoreductase activity
BA177_RS02495	COG1297	OPT oligopeptide transporter protein
BA177_RS02500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BA177_RS02505	COG1127	ABC transporter
BA177_RS02525	COG4658	electron transport chain
BA177_RS02535	COG1595	DNA-templated transcription, initiation
BA177_RS02550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA177_RS02555	COG0165	Argininosuccinate lyase
BA177_RS02575	COG0471	metal ion transport
BA177_RS02585	COG2094	Belongs to the DNA glycosylase MPG family
BA177_RS02590	COG0531	amino acid
BA177_RS02620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA177_RS02635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA177_RS02640	COG1917	Cupin 2, conserved barrel domain protein
BA177_RS02645	COG0527	aspartate kinase activity
BA177_RS02650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA177_RS02665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA177_RS02670	COG4993	Dehydrogenase
BA177_RS02675	COG1115	amino acid carrier protein
BA177_RS02685	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS02700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BA177_RS02710	COG4993	Dehydrogenase
BA177_RS02725	COG5001	Diguanylate cyclase
BA177_RS02725	COG5002	protein histidine kinase activity
BA177_RS02750	COG0697	spore germination
BA177_RS02760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS02795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BA177_RS02820	COG0517	IMP dehydrogenase activity
BA177_RS02820	COG0516	GMP reductase activity
BA177_RS02840	COG0235	Class ii aldolase
BA177_RS02845	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BA177_RS02855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BA177_RS02860	COG0500	methyltransferase
BA177_RS02920	COG0288	reversible hydration of carbon dioxide
BA177_RS02930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA177_RS02945	COG0204	Acyl-transferase
BA177_RS02955	COG2827	Endonuclease containing a URI domain
BA177_RS02975	COG1119	ATPase activity
BA177_RS02980	COG0534	Mate efflux family protein
BA177_RS02985	COG0412	Dienelactone hydrolase
BA177_RS03035	COG5001	Diguanylate cyclase
BA177_RS03035	COG5002	protein histidine kinase activity
BA177_RS03040	COG0655	NAD(P)H dehydrogenase (quinone) activity
BA177_RS03045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BA177_RS03055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA177_RS03065	COG0859	PFAM glycosyl transferase family 9
BA177_RS03070	COG3642	lipopolysaccharide core region biosynthetic process
BA177_RS03075	COG1560	Kdo2-lipid A biosynthetic process
BA177_RS03100	COG1611	Belongs to the LOG family
BA177_RS03120	COG0326	Molecular chaperone. Has ATPase activity
BA177_RS03125	COG1174	glycine betaine transport
BA177_RS03130	COG1125	glycine betaine transport
BA177_RS03130	COG0517	IMP dehydrogenase activity
BA177_RS03135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA177_RS03150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BA177_RS03150	COG3743	rRNA binding
BA177_RS03160	COG2945	thiolester hydrolase activity
BA177_RS03175	COG1872	DUF167
BA177_RS03210	COG0543	2 iron, 2 sulfur cluster binding
BA177_RS03220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BA177_RS03225	COG1678	Uncharacterized ACR, COG1678
BA177_RS03265	COG0840	transmembrane signaling receptor activity
BA177_RS03270	COG2198	Histidine kinase
BA177_RS03270	COG0784	Response regulator, receiver
BA177_RS03270	COG0643	Histidine kinase
BA177_RS03280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BA177_RS03285	COG3023	N-Acetylmuramoyl-L-alanine amidase
BA177_RS03295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA177_RS03300	COG2096	Adenosyltransferase
BA177_RS03305	COG4206	TonB-dependent receptor
BA177_RS03310	COG0483	inositol monophosphate 1-phosphatase activity
BA177_RS03315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BA177_RS03325	COG0154	amidase activity
BA177_RS03345	COG0259	pyridoxamine-phosphate oxidase activity
BA177_RS03350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BA177_RS03360	COG1605	Chorismate mutase
BA177_RS03360	COG0287	Prephenate dehydrogenase
BA177_RS03375	COG1178	ABC-type Fe3 transport system permease component
BA177_RS03385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA177_RS03395	COG1981	membrane
BA177_RS03410	COG0316	Belongs to the HesB IscA family
BA177_RS03415	COG0248	Ppx GppA phosphatase
BA177_RS03430	COG0739	heme binding
BA177_RS03435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BA177_RS03475	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA177_RS03480	COG1805	sodium ion transport
BA177_RS03490	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA177_RS03495	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA177_RS03500	COG2871	sodium ion transport
BA177_RS03505	COG0517	IMP dehydrogenase activity
BA177_RS03505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BA177_RS03505	COG0617	tRNA 3'-terminal CCA addition
BA177_RS03520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BA177_RS03535	COG3040	lipid binding
BA177_RS03540	COG0297	glycogen (starch) synthase activity
BA177_RS03545	COG2813	Specifically methylates the guanine in position
BA177_RS03550	COG4772	TonB-dependent receptor
BA177_RS03595	COG2080	2 iron, 2 sulfur cluster binding
BA177_RS03595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BA177_RS03620	COG1966	Carbon starvation protein
BA177_RS03635	COG4771	TonB-dependent receptor
BA177_RS03650	COG0625	glutathione transferase activity
BA177_RS03680	COG0798	PFAM Bile acid sodium symporter
BA177_RS03685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA177_RS03695	COG1597	lipid kinase activity
BA177_RS03700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA177_RS03710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BA177_RS03745	COG2963	transposase activity
BA177_RS03780	COG0515	serine threonine protein kinase
BA177_RS03780	COG2815	serine threonine protein kinase
BA177_RS03795	COG3550	peptidyl-serine autophosphorylation
BA177_RS03845	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA177_RS03865	COG0110	maltose O-acetyltransferase activity
BA177_RS03870	COG0277	FAD linked oxidase domain protein
BA177_RS03875	COG0277	FAD linked oxidase domain protein
BA177_RS03880	COG0247	lactate metabolic process
BA177_RS03885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA177_RS03895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA177_RS03900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA177_RS03905	COG2706	6-phosphogluconolactonase activity
BA177_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS03925	COG1609	Transcriptional regulator
BA177_RS03935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA177_RS03950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS03955	COG0251	oxidation-reduction process
BA177_RS03975	COG0745	RESPONSE REGULATOR receiver
BA177_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA177_RS03995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS04000	COG1538	Outer membrane efflux protein
BA177_RS04005	COG1136	(ABC) transporter
BA177_RS04005	COG0577	efflux transmembrane transporter activity
BA177_RS04020	COG0330	HflC and HflK could
BA177_RS04030	COG1234	tRNA 3'-trailer cleavage
BA177_RS04045	COG3962	Belongs to the TPP enzyme family
BA177_RS04050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA177_RS04055	COG0673	inositol 2-dehydrogenase activity
BA177_RS04060	COG3718	enzyme involved in inositol metabolism
BA177_RS04100	COG0363	glucosamine-6-phosphate deaminase activity
BA177_RS04120	COG2205	protein histidine kinase activity
BA177_RS04120	COG2202	Pas domain
BA177_RS04125	COG0154	amidase activity
BA177_RS04150	COG0129	dihydroxy-acid dehydratase activity
BA177_RS04155	COG0604	alcohol dehydrogenase
BA177_RS04165	COG2084	Dehydrogenase
BA177_RS04170	COG2814	Major facilitator Superfamily
BA177_RS04175	COG4771	TonB-dependent receptor
BA177_RS04215	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA177_RS04220	COG0579	oxidoreductase
BA177_RS04225	COG2084	Dehydrogenase
BA177_RS04240	COG2203	Gaf domain
BA177_RS04240	COG3706	GGDEF domain
BA177_RS04240	COG4251	negative regulation of phosphorylation
BA177_RS04240	COG5001	Diguanylate cyclase
BA177_RS04275	COG0640	Transcriptional regulator
BA177_RS04285	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA177_RS04320	COG0583	DNA-binding transcription factor activity
BA177_RS04325	COG1917	Cupin 2, conserved barrel domain protein
BA177_RS04330	COG3844	kynureninase activity
BA177_RS04335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA177_RS04350	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BA177_RS04370	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA177_RS04385	COG0589	response to stress
BA177_RS04390	COG4191	Histidine kinase
BA177_RS04395	COG4566	intracellular signal transduction
BA177_RS04400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA177_RS04415	COG4948	Mandelate Racemase Muconate Lactonizing
BA177_RS04445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS04450	COG1757	Na H antiporter
BA177_RS04455	COG0583	DNA-binding transcription factor activity
BA177_RS04465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA177_RS04480	COG2271	Major facilitator Superfamily
BA177_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS04500	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA177_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS04510	COG4948	Mandelate Racemase Muconate Lactonizing
BA177_RS04540	COG3263	regulation of cellular component size
BA177_RS04550	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BA177_RS04570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BA177_RS04570	COG2010	Cytochrome c
BA177_RS04590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA177_RS04595	COG4771	TonB-dependent receptor
BA177_RS04630	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS04635	COG0625	glutathione transferase activity
BA177_RS04640	COG0174	glutamine synthetase
BA177_RS04645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BA177_RS04660	COG0297	glycogen (starch) synthase activity
BA177_RS04665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BA177_RS04705	COG0398	Pfam SNARE associated Golgi protein
BA177_RS04710	COG0583	DNA-binding transcription factor activity
BA177_RS04715	COG0783	Belongs to the Dps family
BA177_RS04750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA177_RS04760	COG2130	NADP-dependent
BA177_RS04770	COG0471	metal ion transport
BA177_RS04790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA177_RS04795	COG2226	methyltransferase
BA177_RS04820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BA177_RS04830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA177_RS04840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BA177_RS04845	COG0081	regulation of translation
BA177_RS04855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BA177_RS04860	COG0222	ribosome binding
BA177_RS04865	COG0085	RNA polymerase activity
BA177_RS04870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BA177_RS04875	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BA177_RS04880	COG0049	tRNA binding
BA177_RS04885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA177_RS04890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BA177_RS04895	COG0051	transcription antitermination factor activity, RNA binding
BA177_RS04900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BA177_RS04905	COG0088	Forms part of the polypeptide exit tunnel
BA177_RS04910	COG0089	rRNA binding
BA177_RS04915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BA177_RS04920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BA177_RS04925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BA177_RS04930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BA177_RS04935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BA177_RS04940	COG0255	Belongs to the universal ribosomal protein uL29 family
BA177_RS04945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BA177_RS04950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BA177_RS04955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BA177_RS04960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BA177_RS04965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BA177_RS04970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BA177_RS04975	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BA177_RS04980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BA177_RS04985	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BA177_RS04990	COG1841	ribosomal large subunit assembly
BA177_RS04995	COG0200	Binds to the 23S rRNA
BA177_RS05000	COG0201	protein transport
BA177_RS05005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BA177_RS05010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BA177_RS05015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BA177_RS05020	COG0202	RNA polymerase activity
BA177_RS05025	COG0203	ribosomal protein L17
BA177_RS05035	COG4221	oxidoreductase activity
BA177_RS05040	COG2154	pterin-4-alpha-carbinolamine dehydratase
BA177_RS05050	COG0405	Gamma-glutamyltransferase
BA177_RS05105	COG4771	TonB-dependent receptor
BA177_RS05155	COG2010	Cytochrome c
BA177_RS05165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BA177_RS05200	COG0789	Transcriptional regulator
BA177_RS05290	COG0583	DNA-binding transcription factor activity
BA177_RS05295	COG0604	alcohol dehydrogenase
BA177_RS05375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA177_RS05400	COG1131	(ABC) transporter
BA177_RS05420	COG1522	sequence-specific DNA binding
BA177_RS05425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA177_RS05440	COG0730	response to heat
BA177_RS05445	COG0531	amino acid
BA177_RS05455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA177_RS05460	COG2205	protein histidine kinase activity
BA177_RS05465	COG4771	TonB-dependent receptor
BA177_RS05480	COG0589	response to stress
BA177_RS05490	COG4566	intracellular signal transduction
BA177_RS05500	COG3278	Belongs to the heme-copper respiratory oxidase family
BA177_RS05525	COG0348	domain, Protein
BA177_RS05560	COG0842	Transport permease protein
BA177_RS05565	COG1131	(ABC) transporter
BA177_RS05575	COG1309	transcriptional regulator
BA177_RS05580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA177_RS05580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA177_RS05585	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA177_RS05585	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA177_RS05605	COG1392	Phosphate transport regulator
BA177_RS05610	COG0306	phosphate transporter
BA177_RS05615	COG0405	Gamma-glutamyltransferase
BA177_RS05630	COG0174	glutamine synthetase
BA177_RS05640	COG1757	Na H antiporter
BA177_RS05655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BA177_RS05660	COG0174	glutamine synthetase
BA177_RS05670	COG0010	Belongs to the arginase family
BA177_RS05680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA177_RS05685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA177_RS05720	COG2204	response regulator
BA177_RS05730	COG0735	belongs to the Fur family
BA177_RS05735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA177_RS05745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BA177_RS05750	COG1960	acyl-CoA dehydrogenase activity
BA177_RS05755	COG1960	acyl-CoA dehydrogenase activity
BA177_RS05760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA177_RS05765	COG0315	cyclic pyranopterin monophosphate synthase activity
BA177_RS05770	COG0315	cyclic pyranopterin monophosphate synthase activity
BA177_RS05770	COG0746	molybdenum cofactor guanylyltransferase activity
BA177_RS05780	COG0314	molybdopterin synthase activity
BA177_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
BA177_RS05815	COG1946	Acyl-CoA thioesterase
BA177_RS05830	COG0588	phosphoglycerate mutase activity
BA177_RS05835	COG2902	Dehydrogenase
BA177_RS05840	COG3483	tryptophan 2,3-dioxygenase activity
BA177_RS05850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BA177_RS05865	COG0183	Belongs to the thiolase family
BA177_RS05875	COG4974	Belongs to the 'phage' integrase family
BA177_RS05880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA177_RS05895	COG1595	DNA-templated transcription, initiation
BA177_RS05905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA177_RS05910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BA177_RS05915	COG0343	queuine tRNA-ribosyltransferase activity
BA177_RS05920	COG1862	Preprotein translocase
BA177_RS05925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA177_RS05955	COG0316	Belongs to the HesB IscA family
BA177_RS05960	COG0105	UTP biosynthetic process
BA177_RS05965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BA177_RS05970	COG3063	Type IV pilus biogenesis stability protein PilW
BA177_RS05975	COG1426	Protein conserved in bacteria
BA177_RS05980	COG0124	histidyl-tRNA synthetase
BA177_RS05995	COG1160	GTP binding
BA177_RS06000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA177_RS06015	COG1570	exodeoxyribonuclease VII activity
BA177_RS06025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BA177_RS06025	COG0519	Catalyzes the synthesis of GMP from XMP
BA177_RS06060	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BA177_RS06095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BA177_RS06130	COG3422	double-strand break repair
BA177_RS06215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA177_RS06230	COG2132	Multicopper oxidase
BA177_RS06245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA177_RS06250	COG1832	CoA-binding protein
BA177_RS06255	COG2030	dehydratase
BA177_RS06265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA177_RS06295	COG0488	(ABC) transporter
BA177_RS06305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BA177_RS06310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BA177_RS06315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA177_RS06315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA177_RS06330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BA177_RS06345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA177_RS06350	COG0515	serine threonine protein kinase
BA177_RS06350	COG2815	serine threonine protein kinase
BA177_RS06395	COG2200	EAL domain
BA177_RS06400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA177_RS06405	COG1956	GAF domain-containing protein
BA177_RS06410	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BA177_RS06415	COG0688	phosphatidylethanolamine metabolic process
BA177_RS06430	COG2890	protein-(glutamine-N5) methyltransferase activity
BA177_RS06435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BA177_RS06440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA177_RS06455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BA177_RS06460	COG0285	dihydrofolate synthase activity
BA177_RS06480	COG2815	serine threonine protein kinase
BA177_RS06480	COG0515	serine threonine protein kinase
BA177_RS06490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA177_RS06495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA177_RS06525	COG0544	peptidyl-prolyl cis-trans isomerase activity
BA177_RS06530	COG0740	serine-type endopeptidase activity
BA177_RS06535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BA177_RS06540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BA177_RS06560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA177_RS06565	COG1301	dicarboxylic acid transport
BA177_RS06570	COG0438	transferase activity, transferring glycosyl groups
BA177_RS06580	COG0741	lytic transglycosylase activity
BA177_RS06580	COG1388	LysM domain
BA177_RS06585	COG2226	methyltransferase
BA177_RS06590	COG0328	RNA-DNA hybrid ribonuclease activity
BA177_RS06600	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA177_RS06605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BA177_RS06615	COG0166	Belongs to the GPI family
BA177_RS06650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA177_RS06670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA177_RS06675	COG0297	glycogen (starch) synthase activity
BA177_RS06680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BA177_RS06685	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BA177_RS06690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA177_RS06725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA177_RS06775	COG0367	asparagine synthase
BA177_RS06785	COG0318	PFAM AMP-dependent synthetase and ligase
BA177_RS06790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BA177_RS06795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA177_RS06805	COG0726	polysaccharide deacetylase
BA177_RS06815	COG1216	Glycosyl transferase, family 2
BA177_RS06845	COG0297	glycogen (starch) synthase activity
BA177_RS06865	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BA177_RS06870	COG0367	asparagine synthase
BA177_RS06875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA177_RS06890	COG0318	PFAM AMP-dependent synthetase and ligase
BA177_RS06940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA177_RS06960	COG1509	lysine 2,3-aminomutase activity
BA177_RS06965	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BA177_RS06975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BA177_RS06980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA177_RS06985	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS07005	COG2204	response regulator
BA177_RS07010	COG2204	response regulator
BA177_RS07020	COG2205	protein histidine kinase activity
BA177_RS07045	COG5002	protein histidine kinase activity
BA177_RS07045	COG5001	Diguanylate cyclase
BA177_RS07055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BA177_RS07060	COG5001	Diguanylate cyclase
BA177_RS07060	COG3447	MASE1 domain protein
BA177_RS07060	COG5002	protein histidine kinase activity
BA177_RS07075	COG0277	FAD linked oxidase domain protein
BA177_RS07085	COG4946	Tricorn protease homolog
BA177_RS07085	COG0793	Belongs to the peptidase S41A family
BA177_RS07090	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS07115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS07120	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BA177_RS07125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA177_RS07140	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS07165	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA177_RS07170	COG1177	transmembrane transport
BA177_RS07175	COG3842	ATPase activity
BA177_RS07180	COG0174	glutamine synthetase
BA177_RS07195	COG1253	flavin adenine dinucleotide binding
BA177_RS07200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA177_RS07215	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BA177_RS07225	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BA177_RS07245	COG1815	bacterial-type flagellum-dependent cell motility
BA177_RS07250	COG1558	bacterial-type flagellum-dependent cell motility
BA177_RS07255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BA177_RS07265	COG4787	bacterial-type flagellum-dependent cell motility
BA177_RS07280	COG1706	bacterial-type flagellum-dependent cell motility
BA177_RS07285	COG3951	Flagellar rod assembly protein muramidase FlgJ
BA177_RS07285	COG1705	Flagellar rod assembly protein muramidase FlgJ
BA177_RS07350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA177_RS07390	COG3190	flagellar
BA177_RS07400	COG1987	bacterial-type flagellum assembly
BA177_RS07415	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA177_RS07455	COG1360	Flagellar Motor Protein
BA177_RS07460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA177_RS07475	COG1199	ATP-dependent helicase activity
BA177_RS07500	COG0704	Plays a role in the regulation of phosphate uptake
BA177_RS07505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BA177_RS07510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA177_RS07520	COG0573	inorganic phosphate transmembrane transporter activity
BA177_RS07530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA177_RS07540	COG2171	N-acyltransferase activity
BA177_RS07545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BA177_RS07550	COG0024	Methionine aminopeptidase
BA177_RS07555	COG0052	Belongs to the universal ribosomal protein uS2 family
BA177_RS07560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BA177_RS07565	COG0528	UMP kinase activity
BA177_RS07570	COG0233	cytoplasmic translational termination
BA177_RS07575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BA177_RS07585	COG0750	zinc metalloprotease
BA177_RS07600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA177_RS07610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA177_RS07615	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA177_RS07620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BA177_RS07625	COG0587	DNA-directed DNA polymerase activity
BA177_RS07630	COG0825	malonyl-CoA metabolic process
BA177_RS07635	COG0037	tRNA processing
BA177_RS07640	COG0504	CTP synthase activity
BA177_RS07645	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BA177_RS07650	COG0148	phosphopyruvate hydratase activity
BA177_RS07655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BA177_RS07660	COG0585	pseudouridine synthase activity
BA177_RS07665	COG1193	negative regulation of DNA recombination
BA177_RS07670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BA177_RS07675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BA177_RS07680	COG1238	metal cluster binding
BA177_RS07705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BA177_RS07715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BA177_RS07725	COG2009	succinate dehydrogenase
BA177_RS07735	COG1053	succinate dehydrogenase
BA177_RS07745	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BA177_RS07780	COG0481	GTPase activity
BA177_RS07785	COG0681	Belongs to the peptidase S26 family
BA177_RS07795	COG0571	ribonuclease III activity
BA177_RS07805	COG1381	Involved in DNA repair and RecF pathway recombination
BA177_RS07810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BA177_RS07825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA177_RS07830	COG1472	Belongs to the glycosyl hydrolase 3 family
BA177_RS07850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA177_RS07860	COG4591	ABC-type transport system involved in lipoprotein release permease component
BA177_RS07870	COG1136	(ABC) transporter
BA177_RS07880	COG2333	competence protein COMEC
BA177_RS07880	COG0658	competence protein
BA177_RS07885	COG0811	peptide transport
BA177_RS07890	COG0848	biopolymer transport protein
BA177_RS07895	COG1132	(ABC) transporter
BA177_RS07900	COG1663	tetraacyldisaccharide 4'-kinase activity
BA177_RS07905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BA177_RS07935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA177_RS07940	COG1530	ribonuclease E activity
BA177_RS07950	COG0424	maF-like protein
BA177_RS07965	COG0416	fatty acid biosynthetic process
BA177_RS07970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA177_RS07995	COG1131	(ABC) transporter
BA177_RS08035	COG1272	protein, Hemolysin III
BA177_RS08075	COG0519	Catalyzes the synthesis of GMP from XMP
BA177_RS08080	COG5001	Diguanylate cyclase
BA177_RS08080	COG5002	protein histidine kinase activity
BA177_RS08095	COG0513	Belongs to the DEAD box helicase family
BA177_RS08110	COG1228	amidohydrolase
BA177_RS08150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BA177_RS08165	COG0587	DNA-directed DNA polymerase activity
BA177_RS08195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BA177_RS08200	COG0542	response to heat
BA177_RS08210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BA177_RS08220	COG0492	ferredoxin-NADP+ reductase activity
BA177_RS08225	COG1674	ftsk spoiiie
BA177_RS08230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BA177_RS08240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BA177_RS08245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BA177_RS08250	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BA177_RS08250	COG3264	Mechanosensitive ion channel
BA177_RS08255	COG0670	Belongs to the BI1 family
BA177_RS08270	COG1757	Na H antiporter
BA177_RS08275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BA177_RS08300	COG0432	Pfam Uncharacterised protein family UPF0047
BA177_RS08320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA177_RS08330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA177_RS08365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA177_RS08385	COG0531	amino acid
BA177_RS08390	COG1770	oligopeptidase
BA177_RS08400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BA177_RS08405	COG1428	Deoxynucleoside kinase
BA177_RS08475	COG1505	serine-type exopeptidase activity
BA177_RS08515	COG0300	oxidoreductase activity
BA177_RS08520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA177_RS08525	COG2738	Putative neutral zinc metallopeptidase
BA177_RS08535	COG1115	amino acid carrier protein
BA177_RS08550	COG3795	YCII-related domain
BA177_RS08555	COG4941	Belongs to the sigma-70 factor family
BA177_RS08560	COG1228	amidohydrolase
BA177_RS08565	COG1228	amidohydrolase
BA177_RS08575	COG2010	Cytochrome c
BA177_RS08590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS08610	COG0745	RESPONSE REGULATOR receiver
BA177_RS08620	COG0076	glutamate decarboxylase activity
BA177_RS08635	COG3064	Membrane
BA177_RS08640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA177_RS08665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BA177_RS08670	COG0602	queuosine metabolic process
BA177_RS08685	COG1136	(ABC) transporter
BA177_RS08690	COG1136	(ABC) transporter
BA177_RS08690	COG0577	efflux transmembrane transporter activity
BA177_RS08695	COG0577	efflux transmembrane transporter activity
BA177_RS08705	COG3177	Filamentation induced by cAMP protein fic
BA177_RS08710	COG1473	amidohydrolase
BA177_RS08720	COG0613	PHP domain protein
BA177_RS08725	COG2814	Major facilitator Superfamily
BA177_RS08740	COG3239	Fatty acid desaturase
BA177_RS08760	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA177_RS08770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA177_RS08775	COG0217	transcriptional regulatory protein
BA177_RS08780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BA177_RS08785	COG0632	four-way junction helicase activity
BA177_RS08790	COG2255	four-way junction helicase activity
BA177_RS08795	COG0824	Thioesterase
BA177_RS08800	COG0811	peptide transport
BA177_RS08815	COG0823	Involved in the tonB-independent uptake of proteins
BA177_RS08820	COG2885	chlorophyll binding
BA177_RS08835	COG0460	homoserine dehydrogenase
BA177_RS08835	COG0527	aspartate kinase activity
BA177_RS08840	COG0083	homoserine kinase activity
BA177_RS08845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BA177_RS08860	COG0084	hydrolase, TatD family'
BA177_RS08870	COG1131	(ABC) transporter
BA177_RS08890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BA177_RS08895	COG0482	sulfurtransferase activity
BA177_RS08900	COG0494	nUDIX hydrolase
BA177_RS08925	COG3956	TIGRFAM MazG family protein
BA177_RS08960	COG0252	asparaginase activity
BA177_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS08970	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BA177_RS08980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA177_RS08990	COG1573	uracil-dna glycosylase
BA177_RS08995	COG0322	excinuclease ABC activity
BA177_RS09025	COG3706	GGDEF domain
BA177_RS09030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA177_RS09035	COG1435	thymidine kinase activity
BA177_RS09045	COG4133	protoheme IX ABC transporter activity
BA177_RS09050	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA177_RS09065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BA177_RS09070	COG1138	Cytochrome C-type biogenesis protein
BA177_RS09075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA177_RS09080	COG3088	subunit of a heme lyase
BA177_RS09100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BA177_RS09115	COG3214	Protein conserved in bacteria
BA177_RS09145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BA177_RS09150	COG1695	Transcriptional regulator
BA177_RS09180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA177_RS09190	COG0501	Belongs to the peptidase M48B family
BA177_RS09205	COG3795	YCII-related domain
BA177_RS09215	COG5507	3-demethylubiquinone-9 3-methyltransferase
BA177_RS09220	COG4941	Belongs to the sigma-70 factor family
BA177_RS09230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA177_RS09235	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BA177_RS09260	COG2211	Major facilitator Superfamily
BA177_RS09265	COG0402	S-adenosylhomocysteine deaminase activity
BA177_RS09270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA177_RS09325	COG3273	potassium ion transport
BA177_RS09325	COG0471	metal ion transport
BA177_RS09360	COG0659	secondary active sulfate transmembrane transporter activity
BA177_RS09370	COG1741	Belongs to the pirin family
BA177_RS09375	COG0583	DNA-binding transcription factor activity
BA177_RS09400	COG2258	MOSC domain
BA177_RS09405	COG0384	phenazine biosynthesis protein PhzF
BA177_RS09410	COG0071	Belongs to the small heat shock protein (HSP20) family
BA177_RS09420	COG1858	cytochrome C peroxidase
BA177_RS09435	COG0584	glycerophosphoryl diester phosphodiesterase
BA177_RS09450	COG1024	Enoyl-CoA hydratase
BA177_RS09450	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA177_RS09470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BA177_RS09475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BA177_RS09480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA177_RS09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BA177_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS09505	COG2165	general secretion pathway protein
BA177_RS09510	COG2165	general secretion pathway protein
BA177_RS09555	COG0436	Aminotransferase
BA177_RS09560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BA177_RS09585	COG0678	peroxiredoxin activity
BA177_RS09590	COG1960	acyl-CoA dehydrogenase activity
BA177_RS09595	COG0633	Ferredoxin
BA177_RS09610	COG0848	biopolymer transport protein
BA177_RS09615	COG0811	peptide transport
BA177_RS09620	COG0811	peptide transport
BA177_RS09630	COG1960	acyl-CoA dehydrogenase activity
BA177_RS09640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA177_RS09645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA177_RS09650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA177_RS09655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BA177_RS09660	COG0066	3-isopropylmalate dehydratase activity
BA177_RS09665	COG0473	3-isopropylmalate dehydrogenase activity
BA177_RS09670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA177_RS09675	COG0626	cystathionine gamma-synthase activity
BA177_RS09685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BA177_RS09690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA177_RS09695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA177_RS09700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA177_RS09700	COG0131	Imidazoleglycerol-phosphate dehydratase
BA177_RS09705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BA177_RS09710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BA177_RS09715	COG0107	imidazoleglycerol-phosphate synthase activity
BA177_RS09720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BA177_RS09720	COG0140	phosphoribosyl-ATP diphosphatase activity
BA177_RS09725	COG0527	aspartate kinase activity
BA177_RS09730	COG0129	dihydroxy-acid dehydratase activity
BA177_RS09735	COG0515	serine threonine protein kinase
BA177_RS09740	COG0277	FAD linked oxidase domain protein
BA177_RS09765	COG0776	regulation of translation
BA177_RS09770	COG0072	phenylalanine-tRNA ligase activity
BA177_RS09770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA177_RS09775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BA177_RS09785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BA177_RS09805	COG0436	Aminotransferase
BA177_RS09815	COG1280	lysine exporter protein (LysE YggA)
BA177_RS09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BA177_RS09825	COG1555	photosystem II stabilization
BA177_RS09830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BA177_RS09840	COG0776	regulation of translation
BA177_RS09850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BA177_RS09855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BA177_RS09865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA177_RS09870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BA177_RS09880	COG0402	S-adenosylhomocysteine deaminase activity
BA177_RS09890	COG0546	phosphoglycolate phosphatase activity
BA177_RS09895	COG1322	Protein conserved in bacteria
BA177_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS09905	COG1187	pseudouridine synthase activity
BA177_RS09910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BA177_RS09920	COG0009	L-threonylcarbamoyladenylate synthase
BA177_RS09925	COG2917	probably involved in intracellular septation
BA177_RS09930	COG2350	Protein conserved in bacteria
BA177_RS09940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA177_RS09955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BA177_RS09960	COG3115	cell septum assembly
BA177_RS09975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA177_RS09980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA177_RS09985	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BA177_RS09990	COG0429	hydrolase of the alpha beta-hydrolase fold
BA177_RS09995	COG0784	Response regulator, receiver
BA177_RS09995	COG3437	response regulator, receiver
BA177_RS10005	COG1185	polyribonucleotide nucleotidyltransferase activity
BA177_RS10010	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BA177_RS10015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BA177_RS10020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BA177_RS10025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BA177_RS10030	COG2251	uridine kinase activity
BA177_RS10030	COG0195	Participates in both transcription termination and antitermination
BA177_RS10045	COG0833	amino acid
BA177_RS10060	COG1007	ATP synthesis coupled electron transport
BA177_RS10075	COG0713	ATP synthesis coupled electron transport
BA177_RS10085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA177_RS10090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BA177_RS10095	COG1034	ATP synthesis coupled electron transport
BA177_RS10100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BA177_RS10105	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BA177_RS10110	COG0649	NAD binding
BA177_RS10115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA177_RS10120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA177_RS10125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA177_RS10135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA177_RS10140	COG0149	triose-phosphate isomerase activity
BA177_RS10145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA177_RS10150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BA177_RS10160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BA177_RS10170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA177_RS10175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BA177_RS10180	COG0505	Belongs to the CarA family
BA177_RS10185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BA177_RS10190	COG0484	heat shock protein binding
BA177_RS10195	COG0443	Heat shock 70 kDa protein
BA177_RS10200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BA177_RS10205	COG1420	regulation of RNA biosynthetic process
BA177_RS10210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA177_RS10215	COG0497	DNA recombination
BA177_RS10225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA177_RS10235	COG2867	negative regulation of translational initiation
BA177_RS10240	COG0733	neurotransmitter:sodium symporter activity
BA177_RS10245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BA177_RS10260	COG0582	viral genome integration into host DNA
BA177_RS10265	COG0848	biopolymer transport protein
BA177_RS10300	COG1217	gtp-binding protein TYPA
BA177_RS10305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA177_RS10320	COG0791	NLP P60 protein
BA177_RS10330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA177_RS10380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BA177_RS10400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BA177_RS10405	COG1162	GTPase activity
BA177_RS10410	COG0537	adenosine 5'-monophosphoramidase activity
BA177_RS10415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BA177_RS10420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BA177_RS10425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BA177_RS10440	COG0436	Aminotransferase
BA177_RS10450	COG0514	ATP-dependent DNA helicase (RecQ)
BA177_RS10455	COG0488	(ABC) transporter
BA177_RS10460	COG2321	neutral zinc metallopeptidase
BA177_RS10470	COG2321	neutral zinc metallopeptidase
BA177_RS10515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA177_RS10520	COG2716	regulation of RNA biosynthetic process
BA177_RS10525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA177_RS10530	COG4783	chaperone-mediated protein folding
BA177_RS10535	COG2853	Lipoprotein
BA177_RS10550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BA177_RS10555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BA177_RS10560	COG1127	ABC transporter
BA177_RS10565	COG3588	fructose-bisphosphate aldolase
BA177_RS10575	COG0719	Fe-S assembly protein
BA177_RS10580	COG0396	ATPase activity
BA177_RS10585	COG0719	Fe-S assembly protein
BA177_RS10590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA177_RS10595	COG0822	iron-sulfur transferase activity
BA177_RS10610	COG1760	l-serine dehydratase
BA177_RS10620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BA177_RS10625	COG0156	8-amino-7-oxononanoate synthase activity
BA177_RS10635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA177_RS10640	COG0616	signal peptide processing
BA177_RS10655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA177_RS10665	COG0335	large ribosomal subunit rRNA binding
BA177_RS10670	COG0336	Belongs to the RNA methyltransferase TrmD family
BA177_RS10675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BA177_RS10680	COG0228	four-way junction DNA binding
BA177_RS10685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BA177_RS10700	COG4536	flavin adenine dinucleotide binding
BA177_RS10710	COG2815	serine threonine protein kinase
BA177_RS10710	COG0515	serine threonine protein kinase
BA177_RS10715	COG0631	protein serine/threonine phosphatase activity
BA177_RS10725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA177_RS10730	COG0305	Participates in initiation and elongation during chromosome replication
BA177_RS10735	COG0359	binds to the 23S rRNA
BA177_RS10745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BA177_RS10750	COG0360	Binds together with S18 to 16S ribosomal RNA
BA177_RS10755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA177_RS10760	COG0557	exoribonuclease II activity
BA177_RS10785	COG1115	amino acid carrier protein
BA177_RS10835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BA177_RS10845	COG0330	HflC and HflK could
BA177_RS10850	COG0330	HflC and HflK could
BA177_RS10855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA177_RS10860	COG1923	regulation of RNA biosynthetic process
BA177_RS10865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BA177_RS10870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BA177_RS10875	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA177_RS10880	COG0802	atpase or kinase
BA177_RS10885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BA177_RS10885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BA177_RS10895	COG2326	polyphosphate kinase activity
BA177_RS10905	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BA177_RS10910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BA177_RS10920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA177_RS10925	COG0617	tRNA 3'-terminal CCA addition
BA177_RS10970	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BA177_RS10990	COG0795	lipopolysaccharide-transporting ATPase activity
BA177_RS10995	COG0795	lipopolysaccharide-transporting ATPase activity
BA177_RS11000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA177_RS11015	COG0525	valine-tRNA ligase activity
BA177_RS11020	COG0714	Associated with various cellular activities
BA177_RS11035	COG2270	Major facilitator Superfamily
BA177_RS11040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BA177_RS11050	COG1573	uracil-dna glycosylase
BA177_RS11055	COG0688	phosphatidylethanolamine metabolic process
BA177_RS11060	COG0442	prolyl-tRNA aminoacylation
BA177_RS11065	COG0741	lytic transglycosylase activity
BA177_RS11065	COG0739	heme binding
BA177_RS11065	COG1196	nuclear chromosome segregation
BA177_RS11070	COG1254	Belongs to the acylphosphatase family
BA177_RS11095	COG0628	permease
BA177_RS11100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA177_RS11110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BA177_RS11115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BA177_RS11120	COG0717	Belongs to the dCTP deaminase family
BA177_RS11125	COG0489	protein tyrosine kinase activity
BA177_RS11130	COG2815	serine threonine protein kinase
BA177_RS11130	COG0515	serine threonine protein kinase
BA177_RS11145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA177_RS11145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA177_RS11150	COG4657	Part of a membrane complex involved in electron transport
BA177_RS11155	COG2878	Part of a membrane complex involved in electron transport
BA177_RS11165	COG4658	electron transport chain
BA177_RS11170	COG4659	FMN binding
BA177_RS11175	COG4660	Part of a membrane complex involved in electron transport
BA177_RS11180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BA177_RS11190	COG3220	belongs to the UPF0276 family
BA177_RS11205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA177_RS11210	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA177_RS11220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA177_RS11255	COG5002	protein histidine kinase activity
BA177_RS11255	COG5001	Diguanylate cyclase
BA177_RS11335	COG0196	riboflavin kinase activity
BA177_RS11340	COG0728	peptidoglycan biosynthetic process
BA177_RS11345	COG0268	Binds directly to 16S ribosomal RNA
BA177_RS11350	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BA177_RS11355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BA177_RS11360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BA177_RS11365	COG0142	geranyltranstransferase activity
BA177_RS11400	COG2855	membrane
BA177_RS11405	COG1999	signal sequence binding
BA177_RS11410	COG2847	Copper chaperone PCu(A)C
BA177_RS11415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BA177_RS11425	COG2030	dehydratase
BA177_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS11430	COG3327	negative regulation of DNA-templated transcription, initiation
BA177_RS11435	COG2050	protein possibly involved in aromatic compounds catabolism
BA177_RS11440	COG3396	Phenylacetate-CoA oxygenase
BA177_RS11445	COG3460	Phenylacetate-CoA oxygenase
BA177_RS11450	COG3396	Phenylacetate-CoA oxygenase
BA177_RS11455	COG2151	metal-sulfur cluster biosynthetic enzyme
BA177_RS11460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BA177_RS11465	COG0183	Belongs to the thiolase family
BA177_RS11480	COG4948	Mandelate Racemase Muconate Lactonizing
BA177_RS11510	COG0842	Transport permease protein
BA177_RS11515	COG1131	(ABC) transporter
BA177_RS11525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BA177_RS11530	COG0058	SHG alpha-glucan phosphorylase activity
BA177_RS11540	COG4771	TonB-dependent receptor
BA177_RS11545	COG4771	TonB-dependent receptor
BA177_RS11550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA177_RS11555	COG0733	neurotransmitter:sodium symporter activity
BA177_RS11560	COG3938	Belongs to the proline racemase family
BA177_RS11565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA177_RS11570	COG0583	DNA-binding transcription factor activity
BA177_RS11580	COG1823	symporter activity
BA177_RS11585	COG4585	Histidine kinase
BA177_RS11615	COG4771	TonB-dependent receptor
BA177_RS11620	COG2814	Major facilitator Superfamily
BA177_RS11630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA177_RS11635	COG0189	ligase activity
BA177_RS11645	COG0189	ligase activity
BA177_RS11645	COG4067	protein conserved in archaea
BA177_RS11650	COG1196	nuclear chromosome segregation
BA177_RS11650	COG3264	Mechanosensitive ion channel
BA177_RS11655	COG0598	Magnesium transport protein CorA
BA177_RS11660	COG5001	Diguanylate cyclase
BA177_RS11660	COG4251	negative regulation of phosphorylation
BA177_RS11660	COG3706	GGDEF domain
BA177_RS11660	COG2203	Gaf domain
BA177_RS11665	COG0745	RESPONSE REGULATOR receiver
BA177_RS11665	COG2205	protein histidine kinase activity
BA177_RS11665	COG4191	Histidine kinase
BA177_RS11675	COG4585	Histidine kinase
BA177_RS11685	COG1230	cation diffusion facilitator family transporter
BA177_RS11690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA177_RS11710	COG0612	Peptidase, M16
BA177_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA177_RS11740	COG2084	Dehydrogenase
BA177_RS11745	COG1960	acyl-CoA dehydrogenase activity
BA177_RS11750	COG1024	Enoyl-CoA hydratase
BA177_RS11755	COG1024	Enoyl-CoA hydratase
BA177_RS11755	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA177_RS11760	COG0183	Belongs to the thiolase family
BA177_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS11785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA177_RS11785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA177_RS11785	COG1703	isobutyryl-CoA mutase activity
BA177_RS11790	COG1309	transcriptional regulator
BA177_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS11825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BA177_RS11830	COG1960	acyl-CoA dehydrogenase activity
BA177_RS11845	COG0347	Belongs to the P(II) protein family
BA177_RS11880	COG2224	Isocitrate lyase
BA177_RS11935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA177_RS11945	COG1704	LemA family
BA177_RS11950	COG0501	Belongs to the peptidase M48B family
BA177_RS11960	COG0668	transmembrane transport
BA177_RS11970	COG0477	Major facilitator Superfamily
BA177_RS11990	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA177_RS11995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BA177_RS12005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BA177_RS12010	COG0440	acetolactate synthase activity
BA177_RS12020	COG0028	Belongs to the TPP enzyme family
BA177_RS12025	COG1506	peptidase
BA177_RS12030	COG4771	TonB-dependent receptor
BA177_RS12045	COG2226	methyltransferase
BA177_RS12060	COG2154	pterin-4-alpha-carbinolamine dehydratase
BA177_RS12065	COG3047	cAMP biosynthetic process
BA177_RS12065	COG2885	chlorophyll binding
BA177_RS12100	COG0515	serine threonine protein kinase
BA177_RS12100	COG2815	serine threonine protein kinase
BA177_RS12120	COG0745	RESPONSE REGULATOR receiver
BA177_RS12135	COG2815	serine threonine protein kinase
BA177_RS12135	COG0515	serine threonine protein kinase
BA177_RS12140	COG0183	Belongs to the thiolase family
BA177_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS12165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BA177_RS12175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA177_RS12175	COG0438	transferase activity, transferring glycosyl groups
BA177_RS12180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BA177_RS12190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA177_RS12210	COG1278	Cold shock
BA177_RS12215	COG2855	membrane
BA177_RS12220	COG1304	FMN binding
BA177_RS12225	COG1612	heme a metabolic process
BA177_RS12230	COG0477	Major facilitator Superfamily
BA177_RS12235	COG0626	cystathionine gamma-synthase activity
BA177_RS12245	COG0515	serine threonine protein kinase
BA177_RS12245	COG2815	serine threonine protein kinase
BA177_RS12260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA177_RS12285	COG2951	lytic endotransglycosylase activity
BA177_RS12385	COG3550	peptidyl-serine autophosphorylation
BA177_RS12390	COG1396	sequence-specific DNA binding
BA177_RS12455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS12465	COG1629	transport
BA177_RS12475	COG4771	TonB-dependent receptor
BA177_RS12495	COG0012	GTP binding
BA177_RS12500	COG0193	aminoacyl-tRNA hydrolase activity
BA177_RS12505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BA177_RS12510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BA177_RS12520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BA177_RS12530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BA177_RS12535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BA177_RS12545	COG2890	protein-(glutamine-N5) methyltransferase activity
BA177_RS12550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA177_RS12555	COG0646	methionine synthase
BA177_RS12555	COG1410	methionine synthase
BA177_RS12570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BA177_RS12575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BA177_RS12580	COG0154	amidase activity
BA177_RS12585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BA177_RS12590	COG1077	Cell shape determining protein MreB Mrl
BA177_RS12595	COG1792	Involved in formation and maintenance of cell shape
BA177_RS12600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BA177_RS12605	COG0768	penicillin binding
BA177_RS12610	COG0772	Belongs to the SEDS family
BA177_RS12615	COG2951	lytic endotransglycosylase activity
BA177_RS12620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BA177_RS12625	COG1686	Belongs to the peptidase S11 family
BA177_RS12630	COG2921	Belongs to the UPF0250 family
BA177_RS12635	COG0321	lipoyl(octanoyl) transferase activity
BA177_RS12640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BA177_RS12645	COG3178	'Phosphotransferase
BA177_RS12650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BA177_RS12655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA177_RS12660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BA177_RS12665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BA177_RS12670	COG2967	ApaG domain
BA177_RS12675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA177_RS12690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA177_RS12725	COG0640	Transcriptional regulator
BA177_RS12735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BA177_RS12740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BA177_RS12745	COG1331	Highly conserved protein containing a thioredoxin domain
BA177_RS12750	COG0739	heme binding
BA177_RS12755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA177_RS12760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BA177_RS12770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BA177_RS12775	COG0509	glycine decarboxylation via glycine cleavage system
BA177_RS12780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BA177_RS12795	COG0189	ligase activity
BA177_RS12805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA177_RS12810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA177_RS12815	COG0006	proline dipeptidase activity
BA177_RS12820	COG3079	Belongs to the UPF0149 family
BA177_RS12845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BA177_RS12855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BA177_RS12860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BA177_RS12870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BA177_RS12885	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BA177_RS12890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BA177_RS12900	COG1295	ribonuclease BN
BA177_RS12905	COG0312	modulator of DNA gyrase
BA177_RS12910	COG3028	Belongs to the UPF0307 family
BA177_RS12925	COG3267	Type II secretory pathway component ExeA
BA177_RS12925	COG3409	Peptidoglycan-binding domain 1 protein
BA177_RS12935	COG0312	modulator of DNA gyrase
BA177_RS12940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA177_RS12955	COG0424	maF-like protein
BA177_RS12960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BA177_RS12970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BA177_RS12975	COG1466	dna polymerase III delta subunit
BA177_RS12980	COG2835	tetraacyldisaccharide 4'-kinase activity
BA177_RS12995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BA177_RS13000	COG2166	iron-sulfur cluster assembly
BA177_RS13005	COG0215	cysteine-tRNA ligase activity
BA177_RS13010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BA177_RS13025	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BA177_RS13030	COG0495	leucyl-tRNA aminoacylation
BA177_RS13035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BA177_RS13040	COG4535	Mg2 and Co2 transporter CorC
BA177_RS13045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BA177_RS13050	COG1702	phosphate starvation-inducible protein PhoH
BA177_RS13055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA177_RS13060	COG2046	Belongs to the sulfate adenylyltransferase family
BA177_RS13060	COG0529	Catalyzes the synthesis of activated sulfate
BA177_RS13070	COG2814	Major facilitator Superfamily
BA177_RS13095	COG3647	Membrane
BA177_RS13105	COG2900	Belongs to the SlyX family
BA177_RS13110	COG0488	(ABC) transporter
BA177_RS13125	COG1278	Cold shock
BA177_RS13140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BA177_RS13165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA177_RS13170	COG2095	MarC family integral membrane protein
BA177_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS13250	COG2197	response regulator
BA177_RS13280	COG0436	Aminotransferase
BA177_RS13315	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS13350	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BA177_RS13395	COG0640	Transcriptional regulator
BA177_RS13405	COG1162	GTPase activity
BA177_RS13420	COG1473	amidohydrolase
BA177_RS13425	COG0010	Belongs to the arginase family
BA177_RS13435	COG0492	ferredoxin-NADP+ reductase activity
BA177_RS13450	COG1757	Na H antiporter
BA177_RS13465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS13470	COG0823	Involved in the tonB-independent uptake of proteins
BA177_RS13470	COG1506	peptidase
BA177_RS13470	COG4946	Tricorn protease homolog
BA177_RS13495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA177_RS13500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA177_RS13505	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BA177_RS13510	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BA177_RS13540	COG1648	precorrin-2 dehydrogenase activity
BA177_RS13540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA177_RS13545	COG0583	DNA-binding transcription factor activity
BA177_RS13550	COG0175	sulfate reduction
BA177_RS13555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA177_RS13560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BA177_RS13590	COG2165	general secretion pathway protein
BA177_RS13595	COG2165	general secretion pathway protein
BA177_RS13600	COG2165	general secretion pathway protein
BA177_RS13610	COG1459	type II secretion system
BA177_RS13615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA177_RS13650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BA177_RS13665	COG1404	Belongs to the peptidase S8 family
BA177_RS13680	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS13690	COG1473	amidohydrolase
BA177_RS13700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BA177_RS13735	COG0457	Tetratricopeptide repeat
BA177_RS13740	COG4771	TonB-dependent receptor
BA177_RS13750	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BA177_RS13755	COG2873	o-acetylhomoserine
BA177_RS13775	COG1629	transport
BA177_RS13775	COG4771	TonB-dependent receptor
BA177_RS13785	COG3174	membrane
BA177_RS13815	COG0456	acetyltransferase
BA177_RS13820	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BA177_RS13825	COG2362	D-Aminopeptidase
BA177_RS13830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BA177_RS13830	COG2010	Cytochrome c
BA177_RS13870	COG3327	negative regulation of DNA-templated transcription, initiation
BA177_RS13925	COG1104	cysteine desulfurase activity
BA177_RS13955	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BA177_RS13960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA177_RS13965	COG2137	regulation of response to DNA damage stimulus
BA177_RS13985	COG0438	transferase activity, transferring glycosyl groups
BA177_RS13995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BA177_RS14000	COG0494	nUDIX hydrolase
BA177_RS14005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BA177_RS14020	COG0542	response to heat
BA177_RS14040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA177_RS14040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BA177_RS14045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BA177_RS14050	COG0045	succinate-CoA ligase (ADP-forming) activity
BA177_RS14090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BA177_RS14095	COG0237	dephospho-CoA kinase activity
BA177_RS14100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BA177_RS14105	COG0494	nUDIX hydrolase
BA177_RS14110	COG0653	protein targeting
BA177_RS14115	COG0739	heme binding
BA177_RS14125	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BA177_RS14130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BA177_RS14140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BA177_RS14145	COG1181	Belongs to the D-alanine--D-alanine ligase family
BA177_RS14150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA177_RS14155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA177_RS14160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA177_RS14165	COG0772	Belongs to the SEDS family
BA177_RS14170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BA177_RS14175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA177_RS14180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA177_RS14185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BA177_RS14195	COG3116	cell division
BA177_RS14205	COG2001	Belongs to the MraZ family
BA177_RS14225	COG0792	nuclease activity
BA177_RS14230	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BA177_RS14240	COG0625	glutathione transferase activity
BA177_RS14245	COG2857	Cytochrome c1
BA177_RS14250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BA177_RS14255	COG0723	plastoquinol--plastocyanin reductase activity
BA177_RS14260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA177_RS14295	COG1137	ATPase activity
BA177_RS14315	COG1660	Displays ATPase and GTPase activities
BA177_RS14320	COG2239	Acts as a magnesium transporter
BA177_RS14330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA177_RS14340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BA177_RS14360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA177_RS14365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BA177_RS14370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BA177_RS14375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BA177_RS14380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BA177_RS14395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA177_RS14405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA177_RS14415	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BA177_RS14420	COG0563	adenylate kinase activity
BA177_RS14425	COG0205	6-phosphofructokinase activity
BA177_RS14430	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BA177_RS14435	COG5002	protein histidine kinase activity
BA177_RS14435	COG5001	Diguanylate cyclase
BA177_RS14445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA177_RS14445	COG0425	Belongs to the sulfur carrier protein TusA family
BA177_RS14450	COG1538	Outer membrane efflux protein
BA177_RS14455	COG1519	Transferase
BA177_RS14460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BA177_RS14460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BA177_RS14470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA177_RS14485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA177_RS14500	COG0617	tRNA 3'-terminal CCA addition
BA177_RS14505	COG1968	undecaprenyl-diphosphatase activity
BA177_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS14530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BA177_RS14535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BA177_RS14540	COG1610	YqeY-like protein
BA177_RS14585	COG1704	LemA family
BA177_RS14655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BA177_RS14660	COG1024	Enoyl-CoA hydratase
BA177_RS14660	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA177_RS14685	COG0668	transmembrane transport
BA177_RS14705	COG0739	heme binding
BA177_RS14710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA177_RS14715	COG0302	gtp cyclohydrolase
BA177_RS14740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BA177_RS14745	COG2267	carboxylic ester hydrolase activity
BA177_RS14755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA177_RS14760	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BA177_RS14780	COG0459	protein refolding
BA177_RS14785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BA177_RS14790	COG4232	protein-disulfide reductase activity
BA177_RS14795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA177_RS14800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BA177_RS14805	COG0511	ligase activity, forming carbon-carbon bonds
BA177_RS14810	COG0439	Biotin carboxylase
BA177_RS14815	COG2264	protein methyltransferase activity
BA177_RS14830	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BA177_RS14840	COG0151	Belongs to the GarS family
BA177_RS14845	COG0303	'Molybdopterin
BA177_RS14870	COG0513	Belongs to the DEAD box helicase family
BA177_RS14875	COG1011	Hydrolase
BA177_RS14890	COG1054	Belongs to the UPF0176 family
BA177_RS14915	COG1160	GTP binding
BA177_RS14920	COG1160	GTP binding
BA177_RS14935	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BA177_RS14955	COG3813	Protein conserved in bacteria
BA177_RS14965	COG2304	oxidoreductase activity
BA177_RS14980	COG1228	amidohydrolase
BA177_RS14995	COG3385	transposase activity
BA177_RS15005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BA177_RS15005	COG4651	solute:proton antiporter activity
BA177_RS15030	COG1253	flavin adenine dinucleotide binding
BA177_RS15100	COG1376	ErfK ybiS ycfS ynhG family protein
BA177_RS15115	COG0616	signal peptide processing
BA177_RS15120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BA177_RS15155	COG2304	oxidoreductase activity
BA177_RS15175	COG0714	Associated with various cellular activities
BA177_RS15190	COG1448	Aminotransferase
BA177_RS15195	COG3453	Protein conserved in bacteria
BA177_RS15195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA177_RS15235	COG2986	histidine ammonia-lyase
BA177_RS15240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BA177_RS15245	COG2188	Transcriptional regulator
BA177_RS15255	COG1228	amidohydrolase
BA177_RS15260	COG2814	Major facilitator Superfamily
BA177_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS15295	COG1506	peptidase
BA177_RS15295	COG0823	Involved in the tonB-independent uptake of proteins
BA177_RS15300	COG0457	Tetratricopeptide repeat
BA177_RS15305	COG4771	TonB-dependent receptor
BA177_RS15310	COG5001	Diguanylate cyclase
BA177_RS15345	COG0402	S-adenosylhomocysteine deaminase activity
BA177_RS15350	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BA177_RS15355	COG4266	Belongs to the allantoicase family
BA177_RS15390	COG2351	hydroxyisourate hydrolase activity
BA177_RS15405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA177_RS15415	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS15420	COG1012	belongs to the aldehyde dehydrogenase family
BA177_RS15430	COG0813	purine-nucleoside phosphorylase activity
BA177_RS15440	COG4771	TonB-dependent receptor
BA177_RS15470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA177_RS15475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA177_RS15480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BA177_RS15495	COG0402	S-adenosylhomocysteine deaminase activity
BA177_RS15520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BA177_RS15525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA177_RS15535	COG1845	cytochrome c oxidase, subunit III
BA177_RS15540	COG1845	cytochrome c oxidase, subunit III
BA177_RS15545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BA177_RS15550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BA177_RS15575	COG0402	S-adenosylhomocysteine deaminase activity
BA177_RS15590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA177_RS15595	COG1183	phosphatidylcholine synthase activity
BA177_RS15600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA177_RS15620	COG1164	Oligoendopeptidase f
BA177_RS15625	COG4783	chaperone-mediated protein folding
BA177_RS15660	COG1368	sulfuric ester hydrolase activity
BA177_RS15670	COG1368	sulfuric ester hydrolase activity
BA177_RS15675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BA177_RS15680	COG1228	amidohydrolase
BA177_RS15690	COG2186	Transcriptional regulator
BA177_RS15705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA177_RS15745	COG1757	Na H antiporter
BA177_RS15760	COG2133	pyrroloquinoline quinone binding
BA177_RS15770	COG1757	Na H antiporter
BA177_RS15780	COG0405	Gamma-glutamyltransferase
BA177_RS15785	COG2010	Cytochrome c
BA177_RS15810	COG1757	Na H antiporter
BA177_RS15820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS15825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BA177_RS15835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA177_RS15840	COG2311	Membrane
BA177_RS15860	COG1652	LysM domain
BA177_RS15865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BA177_RS15875	COG3360	Dodecin
BA177_RS15920	COG1970	mechanosensitive ion channel activity
BA177_RS15925	COG3706	GGDEF domain
BA177_RS15960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA177_RS15970	COG0612	Peptidase, M16
BA177_RS15975	COG0823	Involved in the tonB-independent uptake of proteins
BA177_RS15995	COG1228	amidohydrolase
BA177_RS16005	COG0330	HflC and HflK could
BA177_RS16015	COG1671	Belongs to the UPF0178 family
BA177_RS16020	COG1278	Cold shock
BA177_RS16030	COG1764	response to oxidative stress
BA177_RS16035	COG3118	belongs to the thioredoxin family
BA177_RS16065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA177_RS16070	COG0513	Belongs to the DEAD box helicase family
BA177_RS16080	COG1294	oxidase, subunit
BA177_RS16085	COG1271	oxidase subunit
BA177_RS16095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS16105	COG0457	Tetratricopeptide repeat
BA177_RS16160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA177_RS16160	COG2169	Transcriptional regulator
BA177_RS16185	COG0583	DNA-binding transcription factor activity
BA177_RS16190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA177_RS16195	COG3384	dioxygenase
BA177_RS16205	COG0598	Magnesium transport protein CorA
BA177_RS16225	COG0488	(ABC) transporter
BA177_RS16245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BA177_RS16245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA177_RS16250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA177_RS16250	COG1372	Participates in initiation and elongation during chromosome replication
BA177_RS16285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA177_RS16310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA177_RS16315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA177_RS16320	COG0010	Belongs to the arginase family
BA177_RS16330	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BA177_RS16345	COG3474	cytochrome
BA177_RS16360	COG0697	spore germination
BA177_RS16365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BA177_RS16375	COG1619	proteins homologs of microcin C7 resistance protein MccF
BA177_RS16395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA177_RS16405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA177_RS16410	COG0583	DNA-binding transcription factor activity
BA177_RS16420	COG1773	rubredoxin
BA177_RS16430	COG2050	protein possibly involved in aromatic compounds catabolism
BA177_RS16450	COG2133	pyrroloquinoline quinone binding
BA177_RS16500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
BA177_RS16525	COG3949	Membrane
BA177_RS16530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS16540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS16545	COG4771	TonB-dependent receptor
BA177_RS16550	COG0583	DNA-binding transcription factor activity
BA177_RS16555	COG3048	D-serine ammonia-lyase activity
BA177_RS16565	COG2040	homocysteine
BA177_RS16575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS16595	COG2897	thiosulfate sulfurtransferase activity
BA177_RS16650	COG2610	gluconate transmembrane transporter activity
BA177_RS16655	COG3540	Alkaline phosphatase
BA177_RS16660	COG2186	Transcriptional regulator
BA177_RS16685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA177_RS16700	COG1573	uracil-dna glycosylase
BA177_RS16730	COG1233	COG1233 Phytoene dehydrogenase and related
BA177_RS16740	COG2271	Major facilitator Superfamily
BA177_RS16745	COG0037	tRNA processing
BA177_RS16750	COG2885	chlorophyll binding
BA177_RS16770	COG4948	Mandelate Racemase Muconate Lactonizing
BA177_RS16780	COG1228	amidohydrolase
BA177_RS16790	COG0583	DNA-binding transcription factor activity
BA177_RS16800	COG2957	Belongs to the agmatine deiminase family
BA177_RS16810	COG1166	arginine decarboxylase activity
BA177_RS16830	COG0415	Belongs to the DNA photolyase family
BA177_RS16835	COG5505	Protein of unknown function (DUF819)
BA177_RS16855	COG4585	Histidine kinase
BA177_RS16880	COG1309	transcriptional regulator
BA177_RS16885	COG2081	HI0933 family
BA177_RS16905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BA177_RS16925	COG2824	Alkylphosphonate utilization operon protein PhnA
BA177_RS16945	COG1132	(ABC) transporter
BA177_RS16950	COG3311	Transcriptional regulator
BA177_RS16955	COG1569	PIN domain
BA177_RS17020	COG4974	Belongs to the 'phage' integrase family
BA177_RS17025	COG0358	DNA primase activity
BA177_RS17065	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA177_RS17065	COG1902	pentaerythritol trinitrate reductase activity
BA177_RS17070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA177_RS17090	COG1607	acyl-coa hydrolase
BA177_RS17130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BA177_RS17135	COG1477	protein flavinylation
BA177_RS17175	COG3177	Filamentation induced by cAMP protein fic
BA177_RS17190	COG0625	glutathione transferase activity
BA177_RS17200	COG0069	glutamate synthase activity
BA177_RS17205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA177_RS17220	COG3383	formate dehydrogenase (NAD+) activity
BA177_RS17225	COG0628	permease
BA177_RS17270	COG3237	CsbD-like
BA177_RS17280	COG2205	protein histidine kinase activity
BA177_RS17285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA177_RS17315	COG0745	RESPONSE REGULATOR receiver
BA177_RS17320	COG2205	protein histidine kinase activity
BA177_RS17345	COG4134	Bacterial extracellular solute-binding protein
BA177_RS17355	COG4136	ATPase activity
BA177_RS17360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA177_RS17365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA177_RS17390	COG2197	response regulator
BA177_RS17395	COG4585	Histidine kinase
BA177_RS17410	COG0318	PFAM AMP-dependent synthetase and ligase
BA177_RS17425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA177_RS17430	COG2807	transmembrane transport
BA177_RS17440	COG0471	metal ion transport
BA177_RS17440	COG3273	potassium ion transport
BA177_RS17485	COG3119	arylsulfatase activity
BA177_RS17515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS17555	COG0714	Associated with various cellular activities
BA177_RS17560	COG0583	DNA-binding transcription factor activity
BA177_RS17570	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BA177_RS17580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BA177_RS17585	COG0583	DNA-binding transcription factor activity
BA177_RS17610	COG0515	serine threonine protein kinase
BA177_RS17610	COG2815	serine threonine protein kinase
BA177_RS17620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA177_RS17625	COG1607	acyl-coa hydrolase
BA177_RS17630	COG0436	Aminotransferase
BA177_RS17650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA177_RS17685	COG0686	Belongs to the AlaDH PNT family
BA177_RS17690	COG1522	sequence-specific DNA binding
BA177_RS17695	COG0583	DNA-binding transcription factor activity
BA177_RS17700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BA177_RS17705	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BA177_RS17710	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BA177_RS17725	COG2982	Protein involved in outer membrane biogenesis
BA177_RS17755	COG0159	tryptophan synthase activity
BA177_RS17760	COG0133	tryptophan synthase activity
BA177_RS17765	COG0135	phosphoribosylanthranilate isomerase activity
BA177_RS17770	COG0134	indole-3-glycerol-phosphate synthase activity
BA177_RS17775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BA177_RS17780	COG0512	Glutamine amidotransferase of anthranilate synthase
BA177_RS17785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BA177_RS17790	COG0471	metal ion transport
BA177_RS17790	COG3273	potassium ion transport
BA177_RS17810	COG1666	GTP binding
BA177_RS17815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BA177_RS17825	COG2983	Belongs to the UPF0260 family
BA177_RS17830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA177_RS17835	COG0494	nUDIX hydrolase
BA177_RS17840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BA177_RS17845	COG4181	ATPase activity
BA177_RS17860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BA177_RS17865	COG0284	orotidine-5'-phosphate decarboxylase activity
BA177_RS17870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BA177_RS17875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BA177_RS17880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BA177_RS17925	COG0372	Belongs to the citrate synthase family
BA177_RS17930	COG0254	rRNA binding
BA177_RS17935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA177_RS17940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BA177_RS17945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BA177_RS17955	COG1561	YicC-like family, N-terminal region
BA177_RS17960	COG0194	GDP metabolic process
BA177_RS17965	COG1758	RNA polymerase activity
BA177_RS17970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA177_RS17980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA177_RS17985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BA177_RS17995	COG2226	methyltransferase
BA177_RS18000	COG1565	acr, cog1565
BA177_RS18000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BA177_RS18005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BA177_RS18010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BA177_RS18035	COG0109	protoheme IX farnesyltransferase activity
BA177_RS18065	COG0210	DNA helicase
BA177_RS18070	COG0569	domain protein
BA177_RS18075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA177_RS18090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BA177_RS18095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BA177_RS18100	COG1490	D-aminoacyl-tRNA deacylase activity
BA177_RS18105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA177_RS18135	COG2861	carbohydrate metabolic process
BA177_RS18140	COG0793	Belongs to the peptidase S41A family
BA177_RS18145	COG4942	peptidase
BA177_RS18160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BA177_RS18170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BA177_RS18175	COG0167	dihydroorotate dehydrogenase activity
BA177_RS18180	COG2204	response regulator
BA177_RS18185	COG3852	Histidine kinase
BA177_RS18195	COG0174	glutamine synthetase
BA177_RS18200	COG0752	glycyl-tRNA synthetase alpha subunit
BA177_RS18205	COG0751	glycine-tRNA ligase activity
BA177_RS18210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA177_RS18220	COG0187	DNA topoisomerase II activity
BA177_RS18225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BA177_RS18230	COG0592	DNA-directed DNA polymerase activity