locus-tag	class	description
wCauA_RS00005	COG1253	flavin adenine dinucleotide binding
wCauA_RS00020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
wCauA_RS00045	COG0047	phosphoribosylformylglycinamidine synthase activity
wCauA_RS00065	COG0321	lipoyl(octanoyl) transferase activity
wCauA_RS00080	COG4695	Portal protein
wCauA_RS00100	COG0445	tRNA wobble uridine modification
wCauA_RS00125	COG2963	transposase activity
wCauA_RS00135	COG2801	Transposase and inactivated derivatives
wCauA_RS00140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
wCauA_RS00140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
wCauA_RS00170	COG0312	modulator of DNA gyrase
wCauA_RS00175	COG1104	cysteine desulfurase activity
wCauA_RS00190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
wCauA_RS00200	COG1127	ABC transporter
wCauA_RS00205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
wCauA_RS00210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
wCauA_RS00220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
wCauA_RS00230	COG0492	ferredoxin-NADP+ reductase activity
wCauA_RS00245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_RS00250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
wCauA_RS00255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
wCauA_RS00260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
wCauA_RS00265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
wCauA_RS00315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
wCauA_RS00315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
wCauA_RS00320	COG1007	ATP synthesis coupled electron transport
wCauA_RS00325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_RS00330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
wCauA_RS00335	COG0713	ATP synthesis coupled electron transport
wCauA_RS00340	COG0839	Belongs to the complex I subunit 6 family
wCauA_RS00395	COG0564	pseudouridine synthase activity
wCauA_RS00405	COG0658	competence protein
wCauA_RS00405	COG2333	competence protein COMEC
wCauA_RS00415	COG0259	pyridoxamine-phosphate oxidase activity
wCauA_RS00420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
wCauA_RS00430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
wCauA_RS00445	COG0372	Belongs to the citrate synthase family
wCauA_RS00460	COG4974	Belongs to the 'phage' integrase family
wCauA_RS00470	COG0628	permease
wCauA_RS00475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
wCauA_RS00475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
wCauA_RS00485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
wCauA_RS00500	COG1178	ABC-type Fe3 transport system permease component
wCauA_RS00505	COG1054	Belongs to the UPF0176 family
wCauA_RS00515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
wCauA_RS00530	COG1090	epimerase
wCauA_RS00555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_RS00565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_RS00575	COG0084	hydrolase, TatD family'
wCauA_RS00615	COG2255	four-way junction helicase activity
wCauA_RS00625	COG2094	Belongs to the DNA glycosylase MPG family
wCauA_RS00630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
wCauA_RS00635	COG0772	Belongs to the SEDS family
wCauA_RS00640	COG0651	ATP synthesis coupled electron transport
wCauA_RS00690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
wCauA_RS00695	COG0670	Belongs to the BI1 family
wCauA_RS00700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
wCauA_RS00710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
wCauA_RS00735	COG0531	amino acid
wCauA_RS00745	COG0527	aspartate kinase activity
wCauA_RS00755	COG0126	phosphoglycerate kinase activity
wCauA_RS00770	COG2070	2-Nitropropane dioxygenase
wCauA_RS00785	COG3451	type IV secretory pathway VirB4
wCauA_RS00805	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_RS00820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
wCauA_RS00825	COG0105	UTP biosynthetic process
wCauA_RS00835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
wCauA_RS00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
wCauA_RS00865	COG0142	geranyltranstransferase activity
wCauA_RS00870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
wCauA_RS00875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
wCauA_RS00890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
wCauA_RS00905	COG0723	plastoquinol--plastocyanin reductase activity
wCauA_RS00930	COG1268	BioY protein
wCauA_RS00935	COG0778	Nitroreductase
wCauA_RS00950	COG0045	succinate-CoA ligase (ADP-forming) activity
wCauA_RS00965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
wCauA_RS00995	COG1475	DNA binding
wCauA_RS01025	COG2009	succinate dehydrogenase
wCauA_RS01030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
wCauA_RS01045	COG4591	ABC-type transport system involved in lipoprotein release permease component
wCauA_RS01070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
wCauA_RS01075	COG0312	modulator of DNA gyrase
wCauA_RS01080	COG1278	Cold shock
wCauA_RS01085	COG0513	Belongs to the DEAD box helicase family
wCauA_RS01095	COG1830	Aldolase
wCauA_RS01105	COG0167	dihydroorotate dehydrogenase activity
wCauA_RS01120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
wCauA_RS01170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
wCauA_RS01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
wCauA_RS01190	COG2885	chlorophyll binding
wCauA_RS01220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
wCauA_RS01235	COG0543	2 iron, 2 sulfur cluster binding
wCauA_RS01235	COG0493	'glutamate synthase
wCauA_RS01250	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
wCauA_RS01265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
wCauA_RS01305	COG2003	Belongs to the UPF0758 family
wCauA_RS01325	COG2801	Transposase and inactivated derivatives
wCauA_RS01330	COG3621	Patatin-like phospholipase
wCauA_RS01335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
wCauA_RS01445	COG0071	Belongs to the small heat shock protein (HSP20) family
wCauA_RS01460	COG3932	Exopolysaccharide synthesis, ExoD
wCauA_RS01490	COG2003	Belongs to the UPF0758 family
wCauA_RS01505	COG1395	domain, Protein
wCauA_RS01515	COG3621	Patatin-like phospholipase
wCauA_RS01600	COG3621	Patatin-like phospholipase
wCauA_RS01715	COG2189	Belongs to the N(4) N(6)-methyltransferase family
wCauA_RS01795	COG4804	nuclease activity
wCauA_RS01890	COG3621	Patatin-like phospholipase
wCauA_RS01955	COG1674	ftsk spoiiie
wCauA_RS01990	COG0307	riboflavin synthase, alpha
wCauA_RS02000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
wCauA_RS02005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
wCauA_RS02040	COG2801	Transposase and inactivated derivatives
wCauA_RS02060	COG0489	protein tyrosine kinase activity
wCauA_RS02085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
wCauA_RS02105	COG0193	aminoacyl-tRNA hydrolase activity
wCauA_RS02130	COG0477	Major facilitator Superfamily
wCauA_RS02135	COG0024	Methionine aminopeptidase
wCauA_RS02150	COG0242	peptide deformylase activity
wCauA_RS02155	COG1573	uracil-dna glycosylase
wCauA_RS02180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
wCauA_RS02185	COG0113	porphobilinogen synthase activity
wCauA_RS02195	COG0752	glycyl-tRNA synthetase alpha subunit
wCauA_RS02215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
wCauA_RS02220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
wCauA_RS02270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
wCauA_RS02275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
wCauA_RS02285	COG1845	cytochrome c oxidase, subunit III
wCauA_RS02295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
wCauA_RS02300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
wCauA_RS02310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
wCauA_RS02330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
wCauA_RS02335	COG3827	peptidoglycan binding
wCauA_RS02360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
wCauA_RS02375	COG2801	Transposase and inactivated derivatives
wCauA_RS02400	COG0776	regulation of translation
wCauA_RS02410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
wCauA_RS02430	COG3547	Transposase (IS116 IS110 IS902 family)
wCauA_RS02460	COG0823	Involved in the tonB-independent uptake of proteins
wCauA_RS02465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
wCauA_RS02470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
wCauA_RS02505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
wCauA_RS02520	COG2963	transposase activity
wCauA_RS02540	COG0187	DNA topoisomerase II activity
wCauA_RS02550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
wCauA_RS02565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
wCauA_RS02570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
wCauA_RS02570	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
wCauA_RS02570	COG0506	proline dehydrogenase activity
wCauA_RS02590	COG1686	Belongs to the peptidase S11 family
wCauA_RS02595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
wCauA_RS02610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
wCauA_RS02615	COG0758	DNA mediated transformation
wCauA_RS02620	COG0149	triose-phosphate isomerase activity
wCauA_RS02645	COG2801	Transposase and inactivated derivatives
wCauA_RS02650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
wCauA_RS02655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
wCauA_RS02690	COG2801	Transposase and inactivated derivatives
wCauA_RS02700	COG0237	dephospho-CoA kinase activity
wCauA_RS02705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
wCauA_RS02730	COG1253	flavin adenine dinucleotide binding
wCauA_RS02740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
wCauA_RS02740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
wCauA_RS02775	COG0573	inorganic phosphate transmembrane transporter activity
wCauA_RS02780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
wCauA_RS02785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
wCauA_RS02795	COG2801	Transposase and inactivated derivatives
wCauA_RS02825	COG0085	RNA polymerase activity
wCauA_RS02825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
wCauA_RS02830	COG0222	ribosome binding
wCauA_RS02835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
wCauA_RS02840	COG0081	regulation of translation
wCauA_RS02845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
wCauA_RS02850	COG0250	Participates in transcription elongation, termination and antitermination
wCauA_RS02865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
wCauA_RS02880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
wCauA_RS02885	COG2890	protein-(glutamine-N5) methyltransferase activity
wCauA_RS02895	COG3505	Type IV secretory pathway VirD4
wCauA_RS02900	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
wCauA_RS02915	COG3736	Type IV secretory pathway, component VirB8
wCauA_RS02935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
wCauA_RS02940	COG0174	glutamine synthetase
wCauA_RS02950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
wCauA_RS02960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
wCauA_RS02965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
wCauA_RS02970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
wCauA_RS02980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
wCauA_RS03015	COG0567	Dehydrogenase, E1 component
wCauA_RS03030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
wCauA_RS03055	COG2111	Na H antiporter
wCauA_RS03055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
wCauA_RS03065	COG1006	Multisubunit Na H antiporter MnhC subunit
wCauA_RS03070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
wCauA_RS03090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
wCauA_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
wCauA_RS03100	COG1295	ribonuclease BN
wCauA_RS03115	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
wCauA_RS03120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
wCauA_RS03125	COG2202	Pas domain
wCauA_RS03125	COG2205	protein histidine kinase activity
wCauA_RS03130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
wCauA_RS03150	COG0156	8-amino-7-oxononanoate synthase activity
wCauA_RS03160	COG0326	Molecular chaperone. Has ATPase activity
wCauA_RS03190	COG2814	Major facilitator Superfamily
wCauA_RS03195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
wCauA_RS03200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
wCauA_RS03205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
wCauA_RS03215	COG0756	dUTP diphosphatase activity
wCauA_RS03240	COG3577	Aspartyl protease
wCauA_RS03260	COG1138	Cytochrome C-type biogenesis protein
wCauA_RS03275	COG1301	dicarboxylic acid transport
wCauA_RS03280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
wCauA_RS03285	COG1217	gtp-binding protein TYPA
wCauA_RS03310	COG0542	response to heat
wCauA_RS03315	COG2902	Dehydrogenase
wCauA_RS03375	COG0235	Class ii aldolase
wCauA_RS03385	COG2801	Transposase and inactivated derivatives
wCauA_RS03390	COG1322	Protein conserved in bacteria
wCauA_RS03410	COG0018	arginyl-trna synthetase
wCauA_RS03425	COG2963	transposase activity
wCauA_RS03430	COG0649	NAD binding
wCauA_RS03435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
wCauA_RS03440	COG4536	flavin adenine dinucleotide binding
wCauA_RS03445	COG3750	Belongs to the UPF0335 family
wCauA_RS03450	COG0163	prenyltransferase activity
wCauA_RS03465	COG2801	Transposase and inactivated derivatives
wCauA_RS03510	COG2003	Belongs to the UPF0758 family
wCauA_RS03545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
wCauA_RS03545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
wCauA_RS03550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
wCauA_RS03555	COG0316	Belongs to the HesB IscA family
wCauA_RS03570	COG2945	thiolester hydrolase activity
wCauA_RS03575	COG1104	cysteine desulfurase activity
wCauA_RS03590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
wCauA_RS03600	COG3547	Transposase (IS116 IS110 IS902 family)
wCauA_RS03620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
wCauA_RS03630	COG0574	Belongs to the PEP-utilizing enzyme family
wCauA_RS03630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
wCauA_RS03640	COG1494	fructose-1,6-bisphosphatase
wCauA_RS03655	COG0505	Belongs to the CarA family
wCauA_RS03670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
wCauA_RS03680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
wCauA_RS03695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
wCauA_RS03710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
wCauA_RS03745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
wCauA_RS03755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
wCauA_RS03765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
wCauA_RS03775	COG0201	protein transport
wCauA_RS03785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
wCauA_RS03790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
wCauA_RS03795	COG0202	RNA polymerase activity
wCauA_RS03805	COG0792	nuclease activity
wCauA_RS03810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
wCauA_RS03820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
wCauA_RS03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
wCauA_RS03850	COG2963	transposase activity
wCauA_RS03860	COG2801	Transposase and inactivated derivatives
wCauA_RS03910	COG2963	transposase activity
wCauA_RS03925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
wCauA_RS03930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
wCauA_RS03935	COG0109	protoheme IX farnesyltransferase activity
wCauA_RS03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
wCauA_RS04005	COG0544	peptidyl-prolyl cis-trans isomerase activity
wCauA_RS04015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
wCauA_RS04020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
wCauA_RS04045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
wCauA_RS04060	COG1074	ATP-dependent DNA helicase activity
wCauA_RS04085	COG1714	RDD family
wCauA_RS04095	COG0305	Participates in initiation and elongation during chromosome replication
wCauA_RS04105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
wCauA_RS04115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
wCauA_RS04125	COG0358	DNA primase activity
wCauA_RS04150	COG2963	transposase activity
wCauA_RS04170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
wCauA_RS04240	COG1115	amino acid carrier protein
wCauA_RS04270	COG0459	protein refolding
wCauA_RS04280	COG0354	folic acid binding
wCauA_RS04290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
wCauA_RS04320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
wCauA_RS04340	COG2801	Transposase and inactivated derivatives
wCauA_RS04350	COG2239	Acts as a magnesium transporter
wCauA_RS04390	COG2814	Major facilitator Superfamily
wCauA_RS04400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
wCauA_RS04425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
wCauA_RS04430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
wCauA_RS04435	COG2226	methyltransferase
wCauA_RS04455	COG1132	(ABC) transporter
wCauA_RS04485	COG3474	cytochrome
wCauA_RS04505	COG0142	geranyltranstransferase activity
wCauA_RS04525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
wCauA_RS04550	COG0473	3-isopropylmalate dehydrogenase activity
wCauA_RS04555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
wCauA_RS04560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
wCauA_RS04575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
wCauA_RS04595	COG0360	Binds together with S18 to 16S ribosomal RNA
wCauA_RS04610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
wCauA_RS04615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
wCauA_RS04620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
wCauA_RS04625	COG0629	single-stranded DNA binding
wCauA_RS04680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
wCauA_RS04690	COG0612	Peptidase, M16
wCauA_RS04695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
wCauA_RS04700	COG0196	riboflavin kinase activity
wCauA_RS04715	COG0450	alkyl hydroperoxide reductase
wCauA_RS04730	COG4974	Belongs to the 'phage' integrase family
wCauA_RS04775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
wCauA_RS04780	COG1294	oxidase, subunit
wCauA_RS04785	COG1271	oxidase subunit
wCauA_RS04790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
wCauA_RS04795	COG0612	Peptidase, M16
wCauA_RS04805	COG0343	queuine tRNA-ribosyltransferase activity
wCauA_RS04810	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
wCauA_RS04825	COG0745	RESPONSE REGULATOR receiver
wCauA_RS04835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
wCauA_RS04850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
wCauA_RS04955	COG4804	nuclease activity
wCauA_RS05085	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
wCauA_RS05090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
wCauA_RS05110	COG1132	(ABC) transporter
wCauA_RS05135	COG0697	spore germination
wCauA_RS05190	COG2003	Belongs to the UPF0758 family
wCauA_RS05200	COG0768	penicillin binding
wCauA_RS05230	COG2171	N-acyltransferase activity
wCauA_RS05240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
wCauA_RS05435	COG0071	Belongs to the small heat shock protein (HSP20) family
wCauA_RS05450	COG3932	Exopolysaccharide synthesis, ExoD
wCauA_RS05500	COG2801	Transposase and inactivated derivatives
wCauA_RS05510	COG2963	transposase activity
wCauA_RS05535	COG0653	protein targeting
wCauA_RS05550	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_RS05560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
wCauA_RS05580	COG1862	Preprotein translocase
wCauA_RS05590	COG0052	Belongs to the universal ribosomal protein uS2 family
wCauA_RS05600	COG0528	UMP kinase activity
wCauA_RS05620	COG0575	Belongs to the CDS family
wCauA_RS05630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
wCauA_RS05650	COG2801	Transposase and inactivated derivatives
wCauA_RS05660	COG2963	transposase activity
wCauA_RS05675	COG4133	protoheme IX ABC transporter activity
wCauA_RS05690	COG0477	Major facilitator Superfamily
wCauA_RS05695	COG0564	pseudouridine synthase activity
wCauA_RS05700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
wCauA_RS05705	COG1981	membrane
wCauA_RS05715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
wCauA_RS05725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
wCauA_RS05735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
wCauA_RS05735	COG0072	phenylalanine-tRNA ligase activity
wCauA_RS05745	COG0356	it plays a direct role in the translocation of protons across the membrane
wCauA_RS05750	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
wCauA_RS05775	COG4770	biotin carboxylase activity
wCauA_RS05785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
wCauA_RS05800	COG1053	succinate dehydrogenase
wCauA_RS05810	COG0194	GDP metabolic process
wCauA_RS05835	COG0012	GTP binding
wCauA_RS05845	COG0617	tRNA 3'-terminal CCA addition
wCauA_RS05880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
wCauA_RS05885	COG0805	protein transport
wCauA_RS05890	COG1438	arginine binding
wCauA_RS05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
wCauA_RS05900	COG0765	amino acid transport
wCauA_RS05905	COG1126	abc transporter atp-binding protein
wCauA_RS05925	COG0284	orotidine-5'-phosphate decarboxylase activity
wCauA_RS05940	COG0525	valine-tRNA ligase activity
wCauA_RS05960	COG0504	CTP synthase activity
wCauA_RS05965	COG0590	tRNA wobble adenosine to inosine editing
wCauA_RS05975	COG0477	Major facilitator Superfamily
wCauA_RS05980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
wCauA_RS05985	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_RS05985	COG0022	dehydrogenase e1 component
wCauA_RS06055	COG0739	heme binding
wCauA_RS06065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
wCauA_RS06075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
wCauA_RS06080	COG0280	phosphate acetyltransferase
wCauA_RS06080	COG0281	malic enzyme
wCauA_RS06100	COG0114	fumarate hydratase activity
wCauA_RS06125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
wCauA_RS06155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
wCauA_RS06160	COG0154	amidase activity
wCauA_RS06170	COG2963	transposase activity
wCauA_RS06220	COG0009	L-threonylcarbamoyladenylate synthase
wCauA_RS06240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
wCauA_RS06300	COG0330	HflC and HflK could
wCauA_RS06350	COG0556	nucleotide-excision repair
wCauA_RS06385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
wCauA_RS06390	COG0552	protein localization to endoplasmic reticulum
wCauA_RS06395	COG0822	iron-sulfur transferase activity
wCauA_RS06400	COG0316	Belongs to the HesB IscA family
wCauA_RS06415	COG0681	Belongs to the peptidase S26 family
wCauA_RS06425	COG1840	ABC-type Fe3 transport system, periplasmic component
wCauA_RS06475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
wCauA_RS06490	COG0742	ribosomal rna small subunit methyltransferase
wCauA_RS06500	COG0419	ATPase involved in DNA repair
wCauA_RS06500	COG3704	protein secretion by the type IV secretion system
wCauA_RS06505	COG3704	protein secretion by the type IV secretion system
wCauA_RS06510	COG3704	protein secretion by the type IV secretion system
wCauA_RS06515	COG3704	protein secretion by the type IV secretion system
wCauA_RS06520	COG3451	type IV secretory pathway VirB4
wCauA_RS06530	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
wCauA_RS06545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
wCauA_RS06580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
wCauA_RS06585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
wCauA_RS06590	COG0254	rRNA binding
wCauA_RS06595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
wCauA_RS06625	COG1185	polyribonucleotide nucleotidyltransferase activity
wCauA_RS06635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
wCauA_RS06650	COG3088	subunit of a heme lyase
wCauA_RS06650	COG4235	cytochrome complex assembly
wCauA_RS06680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
wCauA_RS06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
wCauA_RS06690	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
wCauA_RS06730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
wCauA_RS06760	COG0626	cystathionine gamma-synthase activity
wCauA_RS06775	COG1530	ribonuclease E activity
wCauA_RS06780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
wCauA_RS06795	COG1121	(ABC) transporter
wCauA_RS06800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
wCauA_RS06840	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
wCauA_RS06875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
wCauA_RS06880	COG0539	negative regulation of cytoplasmic translation
wCauA_RS06885	COG0776	regulation of translation
wCauA_RS06900	COG0750	zinc metalloprotease
wCauA_RS06920	COG0543	2 iron, 2 sulfur cluster binding
wCauA_RS06920	COG0493	'glutamate synthase
wCauA_RS06935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
wCauA_RS06945	COG0124	histidyl-tRNA synthetase
wCauA_RS06955	COG0484	heat shock protein binding
wCauA_RS06970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
wCauA_RS06975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
wCauA_RS06975	COG2857	Cytochrome c1
wCauA_RS07025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
wCauA_RS07030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
wCauA_RS07055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
wCauA_RS07060	COG2867	negative regulation of translational initiation
wCauA_RS07075	COG0285	dihydrofolate synthase activity
wCauA_RS07080	COG0484	heat shock protein binding
wCauA_RS07085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
wCauA_RS07095	COG1183	phosphatidylcholine synthase activity
wCauA_RS07100	COG1115	amino acid carrier protein
wCauA_RS07105	COG1115	amino acid carrier protein
wCauA_RS07115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
wCauA_RS07125	COG1230	cation diffusion facilitator family transporter
wCauA_RS07145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
wCauA_RS07160	COG0477	Major facilitator Superfamily
wCauA_RS07170	COG0436	Aminotransferase