locus-tag	class	description
GOY14_RS00005	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GOY14_RS00020	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GOY14_RS00035	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GOY14_RS00045	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GOY14_RS00060	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GOY14_RS00075	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GOY14_RS00080	ENOG4105DTN	riboflavin biosynthesis protein ribF
GOY14_RS00095	ENOG4108VX5	3-methyladenine DNA glycosylase
GOY14_RS00100	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GOY14_RS00105	ENOG4105BZG	amino acid carrier protein
GOY14_RS00110	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GOY14_RS00120	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GOY14_RS00125	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GOY14_RS00135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GOY14_RS00145	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GOY14_RS00150	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GOY14_RS00155	ENOG4105CTB	Polyprenyl synthetase
GOY14_RS00170	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GOY14_RS00180	ENOG4108KAG	Cytochrome C oxidase, subunit I
GOY14_RS00185	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GOY14_RS00190	ENOG4105CP7	Triose-phosphate isomerase
GOY14_RS00200	ENOG4105EIE	fructose-bisphosphate aldolase
GOY14_RS00205	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GOY14_RS00220	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GOY14_RS00225	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GOY14_RS00230	ENOG4105CNU	cell division protein FtsK
GOY14_RS00240	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GOY14_RS00245	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GOY14_RS00260	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GOY14_RS00270	ENOG4105DZP	Membrane-associated zinc metalloprotease
GOY14_RS00275	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOY14_RS00285	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GOY14_RS00300	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GOY14_RS00305	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GOY14_RS00315	ENOG4105C8Y	Acetylornithine aminotransferase
GOY14_RS00320	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GOY14_RS00330	ENOG4107RVG	penicillin-binding protein
GOY14_RS00340	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GOY14_RS00345	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GOY14_RS00350	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GOY14_RS00355	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GOY14_RS00370	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GOY14_RS00380	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GOY14_RS00390	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GOY14_RS00400	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GOY14_RS00405	ENOG4105D5Q	Arginine ornithine antiporter
GOY14_RS00420	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GOY14_RS00430	ENOG4105C72	UPF0176 protein
GOY14_RS00435	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GOY14_RS00440	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GOY14_RS00460	ENOG4108Z4V	iron-sulfur cluster assembly
GOY14_RS00465	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GOY14_RS00470	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GOY14_RS00475	ENOG4105K5M	30s ribosomal protein S16
GOY14_RS00480	ENOG4105EAH	synthase
GOY14_RS00485	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GOY14_RS00530	ENOG4105EA8	2-Nitropropane dioxygenase
GOY14_RS00540	ENOG4105C1V	Peptidase, M16
GOY14_RS00550	ENOG41072GX	Peptidase M22 Glycoprotease
GOY14_RS00555	ENOG4105C7S	Dehydrogenase
GOY14_RS00560	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GOY14_RS00565	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GOY14_RS00585	ENOG4105K63	Thioredoxin
GOY14_RS00600	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
GOY14_RS00615	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GOY14_RS00620	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GOY14_RS00630	ENOG4107QX3	carboxylase
GOY14_RS00635	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GOY14_RS00645	ENOG4105C9M	aspartyl-trna synthetase
GOY14_RS00650	ENOG4105CSH	Transporter
GOY14_RS00660	ENOG4105C22	threonyL-tRNA synthetase
GOY14_RS00665	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GOY14_RS00670	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GOY14_RS00680	ENOG4107QIZ	NADH dehydrogenase
GOY14_RS00685	ENOG4105CSM	endonuclease III
GOY14_RS00695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GOY14_RS00705	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GOY14_RS00725	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GOY14_RS00730	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GOY14_RS00735	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GOY14_RS00740	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GOY14_RS00755	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GOY14_RS00760	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GOY14_RS00770	ENOG4105C8S	subunit m
GOY14_RS00785	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GOY14_RS00795	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GOY14_RS00805	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GOY14_RS00810	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GOY14_RS00820	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GOY14_RS00825	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GOY14_RS00835	ENOG4108VZM	50s ribosomal protein L10
GOY14_RS00840	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GOY14_RS00845	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GOY14_RS00850	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GOY14_RS00865	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GOY14_RS00880	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GOY14_RS00890	ENOG4105CPF	Cell wall formation (By similarity)
GOY14_RS00895	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GOY14_RS00900	ENOG4108JJ6	Type I secretion system ATPase
GOY14_RS00920	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GOY14_RS00925	ENOG4105D52	delta-aminolevulinic acid dehydratase
GOY14_RS00930	ENOG4105C3J	Cysteine desulfurase
GOY14_RS00935	ENOG4107QM5	aconitate hydratase
GOY14_RS00945	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GOY14_RS00950	ENOG4108AGE	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GOY14_RS00955	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GOY14_RS00970	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GOY14_RS00975	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GOY14_RS00985	ENOG41087N0	50S ribosomal protein L36
GOY14_RS00995	ENOG41060IM	Heme exporter protein
GOY14_RS01010	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GOY14_RS01025	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GOY14_RS01030	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GOY14_RS01035	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GOY14_RS01040	ENOG4105VGS	50s ribosomal protein l32
GOY14_RS01050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GOY14_RS01060	ENOG4105DC7	peptidase M24
GOY14_RS01070	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GOY14_RS01075	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GOY14_RS01080	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GOY14_RS01085	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GOY14_RS01090	ENOG4105DHZ	alpha beta
GOY14_RS01095	ENOG4107QI6	Cysteine desulfurase
GOY14_RS01105	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GOY14_RS01110	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GOY14_RS01115	ENOG4105DJV	ribulose-phosphate 3-epimerase
GOY14_RS01135	ENOG4105K59	histidine triad (HIT) protein
GOY14_RS01140	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GOY14_RS01145	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GOY14_RS01150	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GOY14_RS01160	ENOG4105F8V	Hydrolase, tatD family
GOY14_RS01165	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GOY14_RS01180	ENOG4105CFH	Aspartokinase
GOY14_RS01185	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GOY14_RS01195	ENOG4108R9S	DSBA oxidoreductase
GOY14_RS01215	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GOY14_RS01240	ENOG4105CUT	histidyl-tRNA synthetase
GOY14_RS01255	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GOY14_RS01260	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GOY14_RS01275	ENOG4107QJN	gtp cyclohydrolase ii
GOY14_RS01280	ENOG4108V42	Type IV secretion system protein VirB8
GOY14_RS01295	ENOG4108EHY	type IV secretion system
GOY14_RS01310	ENOG4108Z03	MAF-like protein
GOY14_RS01315	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GOY14_RS01320	ENOG4107XZX	Involved in the transcription termination process (By similarity)
GOY14_RS01330	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GOY14_RS01335	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GOY14_RS01340	ENOG4105DA4	cytochrome c-type biogenesis protein
GOY14_RS01365	ENOG4105WVQ	Fe-S assembly protein IscX
GOY14_RS01370	ENOG4105KDC	50s ribosomal protein l28
GOY14_RS01375	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GOY14_RS01380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GOY14_RS01385	ENOG4105C7I	Dehydrogenase
GOY14_RS01400	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GOY14_RS01405	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GOY14_RS01415	ENOG4106E2K	dihydroneopterin aldolase
GOY14_RS01420	ENOG4105EEI	dihydropteroate synthase
GOY14_RS01430	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GOY14_RS01435	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GOY14_RS01440	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GOY14_RS01455	ENOG4105C6K	Malic enzyme
GOY14_RS01460	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GOY14_RS01465	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOY14_RS01480	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GOY14_RS01485	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GOY14_RS01495	ENOG4105D4A	Cell wall formation (By similarity)
GOY14_RS01510	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GOY14_RS01515	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GOY14_RS01520	ENOG4105FDK	ABC transporter
GOY14_RS01530	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GOY14_RS01540	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GOY14_RS01555	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GOY14_RS01560	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GOY14_RS01575	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GOY14_RS01590	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GOY14_RS01605	ENOG4105BZ1	(ABC) transporter
GOY14_RS01610	ENOG4105C75	arginyL-tRNA synthetase
GOY14_RS01620	ENOG4105EI2	Pseudouridine synthase
GOY14_RS01625	ENOG4108JYK	Dehydrogenase
GOY14_RS01630	ENOG4108YXA	Membrane
GOY14_RS01640	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GOY14_RS01660	ENOG4105FAV	ABC, transporter
GOY14_RS01670	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GOY14_RS01675	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GOY14_RS01685	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GOY14_RS01690	ENOG4108Z6B	deaminase
GOY14_RS01695	ENOG4105CBT	Fructose-1,6-bisphosphatase
GOY14_RS01700	ENOG4105C3G	gtp-binding protein
GOY14_RS01705	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GOY14_RS01720	ENOG4105C2C	drug resistance transporter, Bcr CflA
GOY14_RS01725	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GOY14_RS01730	ENOG4105CFQ	glutamine synthetase
GOY14_RS01735	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GOY14_RS01740	ENOG4105N82	Endonuclease
GOY14_RS01745	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GOY14_RS01750	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GOY14_RS01765	ENOG4105D7Z	glutathione synthase
GOY14_RS01770	ENOG41082WC	Transport-associated protein
GOY14_RS01780	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GOY14_RS01785	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GOY14_RS01790	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GOY14_RS01795	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GOY14_RS01800	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GOY14_RS01815	ENOG4105BZN	citrate synthase
GOY14_RS01820	ENOG4108ZX6	Electron transport protein SCO1 SenC
GOY14_RS01845	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GOY14_RS01855	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GOY14_RS01885	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GOY14_RS01895	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GOY14_RS01900	ENOG4105C83	adenylosuccinate lyase
GOY14_RS01910	ENOG4105W0E	50S ribosomal protein L33
GOY14_RS01915	ENOG4105C03	ribonuclease
GOY14_RS01925	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GOY14_RS01930	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GOY14_RS01935	ENOG4105K46	50S ribosomal protein l27
GOY14_RS01945	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GOY14_RS01955	ENOG4105M85	Bola protein
GOY14_RS01965	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GOY14_RS01970	ENOG4105CSH	Transporter
GOY14_RS01975	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GOY14_RS01980	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GOY14_RS01995	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GOY14_RS02000	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GOY14_RS02035	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GOY14_RS02050	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GOY14_RS02055	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GOY14_RS02060	ENOG4105DZ1	carboxypeptidase
GOY14_RS02065	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GOY14_RS02080	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GOY14_RS02085	ENOG4105CI3	gtp-binding protein typa
GOY14_RS02090	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GOY14_RS02095	ENOG4105CJW	magnesium transporter
GOY14_RS02100	ENOG4105CPP	Dehydrogenase, E1 component
GOY14_RS02105	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GOY14_RS02110	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GOY14_RS02125	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GOY14_RS02135	ENOG4105KNE	Phosphatidate cytidylyltransferase
GOY14_RS02140	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GOY14_RS02145	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GOY14_RS02150	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GOY14_RS02155	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GOY14_RS02160	ENOG4105CE9	30S ribosomal protein S2
GOY14_RS02180	ENOG4107U9T	Pfam:Ribonuclease_BN
GOY14_RS02185	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GOY14_RS02190	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GOY14_RS02195	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GOY14_RS02200	ENOG4105CDU	Replicative dna helicase
GOY14_RS02215	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GOY14_RS02225	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GOY14_RS02240	ENOG4107RIZ	hflk protein
GOY14_RS02245	ENOG4105EPW	hflc protein
GOY14_RS02255	ENOG4107QKV	phosphomannomutase
GOY14_RS02295	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GOY14_RS02300	ENOG4105HFZ	Membrane
GOY14_RS02320	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GOY14_RS02325	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GOY14_RS02330	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GOY14_RS02335	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GOY14_RS02340	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GOY14_RS02345	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GOY14_RS02350	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GOY14_RS02355	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GOY14_RS02360	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GOY14_RS02365	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GOY14_RS02370	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GOY14_RS02375	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GOY14_RS02385	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GOY14_RS02390	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GOY14_RS02400	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GOY14_RS02405	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GOY14_RS02410	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GOY14_RS02415	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GOY14_RS02420	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GOY14_RS02425	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GOY14_RS02430	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GOY14_RS02435	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GOY14_RS02445	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GOY14_RS02465	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GOY14_RS02480	ENOG4108Z4U	Ferredoxin
GOY14_RS02485	ENOG4108MDK	Dehydrogenase
GOY14_RS02490	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GOY14_RS02495	ENOG4105D3R	alkyl hydroperoxide reductase
GOY14_RS02500	ENOG4105C3M	thioredoxin reductase
GOY14_RS02510	ENOG4107QN2	dihydrolipoyl dehydrogenase
GOY14_RS02530	ENOG4108UJD	30S ribosomal protein S9
GOY14_RS02545	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GOY14_RS02560	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GOY14_RS02580	ENOG4105F0N	pyrophosphate phospho-hydrolase
GOY14_RS02595	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GOY14_RS02600	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GOY14_RS02610	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GOY14_RS02625	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GOY14_RS02630	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GOY14_RS02635	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GOY14_RS02640	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GOY14_RS02655	ENOG4105C8T	Leucyl-tRNA synthetase
GOY14_RS02665	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GOY14_RS02695	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GOY14_RS02700	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GOY14_RS02715	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GOY14_RS02720	ENOG4105CNI	cell division protein FtsW
GOY14_RS02725	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GOY14_RS02740	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GOY14_RS02755	ENOG4105C8N	cysteinyl-tRNA synthetase
GOY14_RS02765	ENOG4105BZA	Phosphoglycerate kinase
GOY14_RS02770	ENOG4105CAY	ferredoxin--nadp reductase
GOY14_RS02775	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GOY14_RS02780	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GOY14_RS02785	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GOY14_RS02790	ENOG4105C8U	phosphate abc transporter
GOY14_RS02795	ENOG4105VG0	50S ribosomal protein l34
GOY14_RS02800	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GOY14_RS02835	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GOY14_RS02840	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GOY14_RS02845	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GOY14_RS02855	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GOY14_RS02880	ENOG4105G9V	cytochrome C
GOY14_RS02890	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GOY14_RS02895	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GOY14_RS02900	ENOG4105C9Q	fumarate hydratase class II
GOY14_RS02930	ENOG4106Q4M	protein secretion by the type IV secretion system
GOY14_RS02945	ENOG4106H78	methyltransferase
GOY14_RS02950	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GOY14_RS02965	ENOG4105KWW	Biogenesis protein
GOY14_RS02970	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GOY14_RS02985	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GOY14_RS02990	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GOY14_RS02995	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GOY14_RS03015	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GOY14_RS03025	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GOY14_RS03045	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GOY14_RS03055	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
GOY14_RS03060	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GOY14_RS03080	ENOG4105E33	succinate dehydrogenase
GOY14_RS03085	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GOY14_RS03095	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GOY14_RS03100	ENOG4105CAS	nag kinase
GOY14_RS03105	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GOY14_RS03110	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GOY14_RS03125	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GOY14_RS03130	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GOY14_RS03135	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GOY14_RS03155	ENOG4105VIE	preprotein translocase, subunit YajC
GOY14_RS03165	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GOY14_RS03170	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GOY14_RS03175	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GOY14_RS03180	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GOY14_RS03190	ENOG4105PGM	cation diffusion facilitator family transporter
GOY14_RS03210	ENOG41082FS	50S ribosomal protein L31
GOY14_RS03215	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GOY14_RS03220	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GOY14_RS03225	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GOY14_RS03230	ENOG4105K6T	rare lipoprotein A
GOY14_RS03260	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GOY14_RS03265	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GOY14_RS03270	ENOG4105E2Z	phosphate ABC transporter (Permease
GOY14_RS03275	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GOY14_RS03280	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GOY14_RS03285	ENOG4107QPR	SAICAR synthetase
GOY14_RS03290	ENOG4105CXB	phosphoribosylaminoimidazole synthetase