locus-tag	class	description
GOY12_RS00015	COG0436	Aminotransferase
GOY12_RS00030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOY12_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GOY12_RS00050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOY12_RS00050	COG0519	Catalyzes the synthesis of GMP from XMP
GOY12_RS00055	COG1253	flavin adenine dinucleotide binding
GOY12_RS00075	COG0612	Peptidase, M16
GOY12_RS00080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GOY12_RS00085	COG0196	riboflavin kinase activity
GOY12_RS00090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GOY12_RS00100	COG2094	Belongs to the DNA glycosylase MPG family
GOY12_RS00115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOY12_RS00125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GOY12_RS00130	COG1115	amino acid carrier protein
GOY12_RS00135	COG1183	phosphatidylcholine synthase activity
GOY12_RS00145	COG0149	triose-phosphate isomerase activity
GOY12_RS00150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GOY12_RS00150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GOY12_RS00155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOY12_RS00160	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GOY12_RS00165	COG0343	queuine tRNA-ribosyltransferase activity
GOY12_RS00180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOY12_RS00185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOY12_RS00195	COG0154	amidase activity
GOY12_RS00205	COG0571	ribonuclease III activity
GOY12_RS00210	COG0167	dihydroorotate dehydrogenase activity
GOY12_RS00225	COG1830	Aldolase
GOY12_RS00250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GOY12_RS00260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOY12_RS00265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOY12_RS00270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GOY12_RS00280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GOY12_RS00285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GOY12_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GOY12_RS00295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GOY12_RS00300	COG0756	dUTP diphosphatase activity
GOY12_RS00335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GOY12_RS00340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GOY12_RS00345	COG0745	RESPONSE REGULATOR receiver
GOY12_RS00355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GOY12_RS00375	COG0156	8-amino-7-oxononanoate synthase activity
GOY12_RS00385	COG0326	Molecular chaperone. Has ATPase activity
GOY12_RS00405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOY12_RS00415	COG2885	chlorophyll binding
GOY12_RS00430	COG0482	sulfurtransferase activity
GOY12_RS00435	COG3088	subunit of a heme lyase
GOY12_RS00450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GOY12_RS00480	COG3704	protein secretion by the type IV secretion system
GOY12_RS00485	COG3704	protein secretion by the type IV secretion system
GOY12_RS00490	COG3704	protein secretion by the type IV secretion system
GOY12_RS00495	COG3451	type IV secretory pathway VirB4
GOY12_RS00505	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GOY12_RS00510	COG0114	fumarate hydratase activity
GOY12_RS00515	COG0138	bifunctional purine biosynthesis protein purh
GOY12_RS00525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GOY12_RS00540	COG3474	cytochrome
GOY12_RS00550	COG0187	DNA topoisomerase II activity
GOY12_RS00560	COG0543	2 iron, 2 sulfur cluster binding
GOY12_RS00560	COG0493	'glutamate synthase
GOY12_RS00570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GOY12_RS00580	COG0752	glycyl-tRNA synthetase alpha subunit
GOY12_RS00585	COG0751	glycine-tRNA ligase activity
GOY12_RS00590	COG0322	excinuclease ABC activity
GOY12_RS00625	COG0594	ribonuclease P activity
GOY12_RS00630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GOY12_RS00635	COG0573	inorganic phosphate transmembrane transporter activity
GOY12_RS00645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GOY12_RS00655	COG0492	ferredoxin-NADP+ reductase activity
GOY12_RS00660	COG0126	phosphoglycerate kinase activity
GOY12_RS00665	COG0215	cysteine-tRNA ligase activity
GOY12_RS00670	COG3932	Exopolysaccharide synthesis, ExoD
GOY12_RS00680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GOY12_RS00685	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GOY12_RS00700	COG0651	ATP synthesis coupled electron transport
GOY12_RS00705	COG0772	Belongs to the SEDS family
GOY12_RS00710	COG2171	N-acyltransferase activity
GOY12_RS00730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOY12_RS00735	COG4770	biotin carboxylase activity
GOY12_RS00755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GOY12_RS00760	COG0356	it plays a direct role in the translocation of protons across the membrane
GOY12_RS00770	COG0495	leucyl-tRNA aminoacylation
GOY12_RS00785	COG1160	GTP binding
GOY12_RS00795	COG0849	cell division
GOY12_RS00800	COG0242	peptide deformylase activity
GOY12_RS00805	COG1573	uracil-dna glycosylase
GOY12_RS00820	COG1034	ATP synthesis coupled electron transport
GOY12_RS00825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GOY12_RS00835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GOY12_RS00850	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GOY12_RS00855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GOY12_RS00875	COG0194	GDP metabolic process
GOY12_RS00890	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GOY12_RS00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOY12_RS00930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GOY12_RS00935	COG0492	ferredoxin-NADP+ reductase activity
GOY12_RS00940	COG0450	alkyl hydroperoxide reductase
GOY12_RS00945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOY12_RS00960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GOY12_RS00990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GOY12_RS01000	COG0505	Belongs to the CarA family
GOY12_RS01015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOY12_RS01025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GOY12_RS01030	COG0088	Forms part of the polypeptide exit tunnel
GOY12_RS01035	COG0089	rRNA binding
GOY12_RS01040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GOY12_RS01045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GOY12_RS01050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GOY12_RS01055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GOY12_RS01060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GOY12_RS01075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GOY12_RS01080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GOY12_RS01085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GOY12_RS01090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GOY12_RS01095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GOY12_RS01105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GOY12_RS01110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GOY12_RS01115	COG0200	Binds to the 23S rRNA
GOY12_RS01120	COG0201	protein transport
GOY12_RS01125	COG0563	adenylate kinase activity
GOY12_RS01130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GOY12_RS01135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GOY12_RS01140	COG0202	RNA polymerase activity
GOY12_RS01145	COG0203	ribosomal protein L17
GOY12_RS01155	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GOY12_RS01160	COG0670	Belongs to the BI1 family
GOY12_RS01165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GOY12_RS01185	COG2009	succinate dehydrogenase
GOY12_RS01190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GOY12_RS01205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOY12_RS01210	COG1295	ribonuclease BN
GOY12_RS01215	COG4221	oxidoreductase activity
GOY12_RS01230	COG0052	Belongs to the universal ribosomal protein uS2 family
GOY12_RS01235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GOY12_RS01240	COG0528	UMP kinase activity
GOY12_RS01245	COG0233	cytoplasmic translational termination
GOY12_RS01250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GOY12_RS01255	COG0575	Belongs to the CDS family
GOY12_RS01280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GOY12_RS01280	COG0574	Belongs to the PEP-utilizing enzyme family
GOY12_RS01285	COG1494	fructose-1,6-bisphosphatase
GOY12_RS01290	COG0012	GTP binding
GOY12_RS01295	COG0617	tRNA 3'-terminal CCA addition
GOY12_RS01305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GOY12_RS01310	COG2814	Major facilitator Superfamily
GOY12_RS01320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GOY12_RS01335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GOY12_RS01340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOY12_RS01345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GOY12_RS01355	COG0567	Dehydrogenase, E1 component
GOY12_RS01360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GOY12_RS01370	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GOY12_RS01375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GOY12_RS01380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GOY12_RS01380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GOY12_RS01385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GOY12_RS01395	COG0556	nucleotide-excision repair
GOY12_RS01400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GOY12_RS01400	COG2857	Cytochrome c1
GOY12_RS01405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GOY12_RS01410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GOY12_RS01420	COG0280	phosphate acetyltransferase
GOY12_RS01420	COG0281	malic enzyme
GOY12_RS01425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOY12_RS01430	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GOY12_RS01440	COG0741	lytic transglycosylase activity
GOY12_RS01440	COG0739	heme binding
GOY12_RS01440	COG1196	nuclear chromosome segregation
GOY12_RS01450	COG0481	GTPase activity
GOY12_RS01455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GOY12_RS01465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GOY12_RS01475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOY12_RS01480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GOY12_RS01485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GOY12_RS01490	COG1121	(ABC) transporter
GOY12_RS01495	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GOY12_RS01500	COG0105	UTP biosynthetic process
GOY12_RS01510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GOY12_RS01530	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GOY12_RS01535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOY12_RS01535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOY12_RS01545	COG0312	modulator of DNA gyrase
GOY12_RS01565	COG0708	Exodeoxyribonuclease III
GOY12_RS01590	COG0330	HflC and HflK could
GOY12_RS01605	COG1324	tolerance protein
GOY12_RS01620	COG0459	protein refolding
GOY12_RS01630	COG0354	folic acid binding
GOY12_RS01635	COG1322	Protein conserved in bacteria
GOY12_RS01640	COG0358	DNA primase activity
GOY12_RS01645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GOY12_RS01650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOY12_RS01655	COG0305	Participates in initiation and elongation during chromosome replication
GOY12_RS01665	COG1714	RDD family
GOY12_RS01675	COG0072	phenylalanine-tRNA ligase activity
GOY12_RS01675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOY12_RS01680	COG1686	Belongs to the peptidase S11 family
GOY12_RS01685	COG0525	valine-tRNA ligase activity
GOY12_RS01690	COG0284	orotidine-5'-phosphate decarboxylase activity
GOY12_RS01715	COG0484	heat shock protein binding
GOY12_RS01720	COG0022	dehydrogenase e1 component
GOY12_RS01720	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOY12_RS01725	COG2239	Acts as a magnesium transporter
GOY12_RS01730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GOY12_RS01745	COG0805	protein transport
GOY12_RS01765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOY12_RS01770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GOY12_RS01780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOY12_RS01805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GOY12_RS01810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GOY12_RS01815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GOY12_RS01825	COG1132	(ABC) transporter
GOY12_RS01830	COG0018	arginyl-trna synthetase
GOY12_RS01840	COG0564	pseudouridine synthase activity
GOY12_RS01845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GOY12_RS01860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GOY12_RS01880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GOY12_RS01890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GOY12_RS01895	COG1074	ATP-dependent DNA helicase activity
GOY12_RS01905	COG0504	CTP synthase activity
GOY12_RS01910	COG0590	tRNA wobble adenosine to inosine editing
GOY12_RS01920	COG0477	Major facilitator Superfamily
GOY12_RS01930	COG0626	cystathionine gamma-synthase activity
GOY12_RS01945	COG1845	cytochrome c oxidase, subunit III
GOY12_RS01950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GOY12_RS01960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GOY12_RS01965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GOY12_RS01970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GOY12_RS01980	COG1530	ribonuclease E activity
GOY12_RS01985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GOY12_RS02000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GOY12_RS02005	COG0359	binds to the 23S rRNA
GOY12_RS02010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GOY12_RS02015	COG0360	Binds together with S18 to 16S ribosomal RNA
GOY12_RS02060	COG0045	succinate-CoA ligase (ADP-forming) activity
GOY12_RS02070	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GOY12_RS02080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GOY12_RS02085	COG1999	signal sequence binding
GOY12_RS02090	COG0372	Belongs to the citrate synthase family
GOY12_RS02105	COG4974	Belongs to the 'phage' integrase family
GOY12_RS02125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GOY12_RS02130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GOY12_RS02135	COG0740	serine-type endopeptidase activity
GOY12_RS02140	COG0544	peptidyl-prolyl cis-trans isomerase activity
GOY12_RS02165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOY12_RS02180	COG2902	Dehydrogenase
GOY12_RS02185	COG0542	response to heat
GOY12_RS02190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GOY12_RS02195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GOY12_RS02215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GOY12_RS02220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GOY12_RS02225	COG2890	protein-(glutamine-N5) methyltransferase activity
GOY12_RS02230	COG1138	Cytochrome C-type biogenesis protein
GOY12_RS02250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOY12_RS02260	COG0424	maF-like protein
GOY12_RS02280	COG3505	Type IV secretory pathway VirD4
GOY12_RS02285	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GOY12_RS02300	COG3736	Type IV secretory pathway, component VirB8
GOY12_RS02305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOY12_RS02305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOY12_RS02325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GOY12_RS02330	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GOY12_RS02335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GOY12_RS02345	COG0124	histidyl-tRNA synthetase
GOY12_RS02355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOY12_RS02365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GOY12_RS02370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GOY12_RS02410	COG0285	dihydrofolate synthase activity
GOY12_RS02415	COG0527	aspartate kinase activity
GOY12_RS02425	COG0799	negative regulation of ribosome biogenesis
GOY12_RS02430	COG0494	nUDIX hydrolase
GOY12_RS02435	COG0084	hydrolase, TatD family'
GOY12_RS02445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOY12_RS02450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOY12_RS02455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOY12_RS02480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GOY12_RS02485	COG1185	polyribonucleotide nucleotidyltransferase activity
GOY12_RS02505	COG1104	cysteine desulfurase activity
GOY12_RS02510	COG2945	thiolester hydrolase activity
GOY12_RS02515	COG1136	(ABC) transporter
GOY12_RS02520	COG0316	Belongs to the HesB IscA family
GOY12_RS02525	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GOY12_RS02535	COG0445	tRNA wobble uridine modification
GOY12_RS02540	COG0006	proline dipeptidase activity
GOY12_RS02550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOY12_RS02560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GOY12_RS02565	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GOY12_RS02570	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GOY12_RS02570	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GOY12_RS02575	COG1007	ATP synthesis coupled electron transport
GOY12_RS02580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOY12_RS02585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GOY12_RS02590	COG0713	ATP synthesis coupled electron transport
GOY12_RS02595	COG0839	Belongs to the complex I subunit 6 family
GOY12_RS02605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GOY12_RS02615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GOY12_RS02625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GOY12_RS02630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GOY12_RS02655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GOY12_RS02680	COG1104	cysteine desulfurase activity
GOY12_RS02685	COG0113	porphobilinogen synthase activity
GOY12_RS02690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOY12_RS02695	COG0629	single-stranded DNA binding
GOY12_RS02725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GOY12_RS02730	COG1181	Belongs to the D-alanine--D-alanine ligase family
GOY12_RS02740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GOY12_RS02750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GOY12_RS02755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOY12_RS02770	COG0250	Participates in transcription elongation, termination and antitermination
GOY12_RS02775	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GOY12_RS02780	COG0081	regulation of translation
GOY12_RS02785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GOY12_RS02790	COG0222	ribosome binding
GOY12_RS02795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GOY12_RS02795	COG0085	RNA polymerase activity
GOY12_RS02800	COG0024	Methionine aminopeptidase
GOY12_RS02805	COG0513	Belongs to the DEAD box helicase family
GOY12_RS02810	COG1278	Cold shock
GOY12_RS02815	COG0312	modulator of DNA gyrase
GOY12_RS02820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GOY12_RS02830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GOY12_RS02840	COG1758	RNA polymerase activity
GOY12_RS02870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOY12_RS02895	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GOY12_RS02905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GOY12_RS02925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GOY12_RS02930	COG0649	NAD binding
GOY12_RS02945	COG0259	pyridoxamine-phosphate oxidase activity
GOY12_RS02950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GOY12_RS02965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GOY12_RS02970	COG4133	protoheme IX ABC transporter activity
GOY12_RS02980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GOY12_RS02990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GOY12_RS03000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOY12_RS03005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GOY12_RS03020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GOY12_RS03025	COG0473	3-isopropylmalate dehydrogenase activity
GOY12_RS03050	COG3118	belongs to the thioredoxin family
GOY12_RS03070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOY12_RS03070	COG1372	Participates in initiation and elongation during chromosome replication
GOY12_RS03075	COG0653	protein targeting
GOY12_RS03090	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOY12_RS03110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GOY12_RS03115	COG0612	Peptidase, M16
GOY12_RS03125	COG2070	2-Nitropropane dioxygenase
GOY12_RS03135	COG3451	type IV secretory pathway VirB4
GOY12_RS03145	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOY12_RS03160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GOY12_RS03165	COG0142	geranyltranstransferase activity
GOY12_RS03170	COG0228	four-way junction DNA binding
GOY12_RS03175	COG0552	protein localization to endoplasmic reticulum
GOY12_RS03180	COG0822	iron-sulfur transferase activity
GOY12_RS03185	COG0316	Belongs to the HesB IscA family
GOY12_RS03200	COG0681	Belongs to the peptidase S26 family
GOY12_RS03205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOY12_RS03210	COG4536	flavin adenine dinucleotide binding
GOY12_RS03215	COG3750	Belongs to the UPF0335 family
GOY12_RS03220	COG0163	prenyltransferase activity
GOY12_RS03225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GOY12_RS03245	COG0442	prolyl-tRNA aminoacylation
GOY12_RS03250	COG0736	holo-[acyl-carrier-protein] synthase activity
GOY12_RS03260	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GOY12_RS03275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GOY12_RS03280	COG0723	plastoquinol--plastocyanin reductase activity
GOY12_RS03290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GOY12_RS03300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GOY12_RS03315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GOY12_RS03325	COG1178	ABC-type Fe3 transport system permease component
GOY12_RS03335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GOY12_RS03340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GOY12_RS03355	COG0531	amino acid
GOY12_RS03370	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GOY12_RS03380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GOY12_RS03385	COG1007	ATP synthesis coupled electron transport
GOY12_RS03390	COG0493	'glutamate synthase
GOY12_RS03390	COG0543	2 iron, 2 sulfur cluster binding
GOY12_RS03395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GOY12_RS03410	COG0750	zinc metalloprotease
GOY12_RS03425	COG0539	negative regulation of cytoplasmic translation
GOY12_RS03445	COG0101	tRNA pseudouridine synthase activity
GOY12_RS03450	COG0592	DNA-directed DNA polymerase activity
GOY12_RS03460	COG1674	ftsk spoiiie
GOY12_RS03465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GOY12_RS03470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GOY12_RS03495	COG1862	Preprotein translocase
GOY12_RS03505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GOY12_RS03520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GOY12_RS03525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOY12_RS03535	COG1230	cation diffusion facilitator family transporter
GOY12_RS03555	COG1840	ABC-type Fe3 transport system, periplasmic component
GOY12_RS03560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GOY12_RS03565	COG0254	rRNA binding
GOY12_RS03570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOY12_RS03575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GOY12_RS03585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GOY12_RS03595	COG0148	phosphopyruvate hydratase activity
GOY12_RS03600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GOY12_RS03610	COG0321	lipoyl(octanoyl) transferase activity
GOY12_RS03615	COG0047	phosphoribosylformylglycinamidine synthase activity
GOY12_RS03630	COG0336	Belongs to the RNA methyltransferase TrmD family
GOY12_RS03635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GOY12_RS03640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity