locus-tag	class	description
ONI09_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ONI09_RS00025	COG3736	Type IV secretory pathway, component VirB8
ONI09_RS00040	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ONI09_RS00045	COG3505	Type IV secretory pathway VirD4
ONI09_RS00055	COG2890	protein-(glutamine-N5) methyltransferase activity
ONI09_RS00065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ONI09_RS00080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ONI09_RS00095	COG0250	Participates in transcription elongation, termination and antitermination
ONI09_RS00100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ONI09_RS00105	COG0081	regulation of translation
ONI09_RS00110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ONI09_RS00115	COG0222	ribosome binding
ONI09_RS00120	COG0085	RNA polymerase activity
ONI09_RS00120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ONI09_RS00125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ONI09_RS00135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ONI09_RS00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ONI09_RS00160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ONI09_RS00165	COG0823	Involved in the tonB-independent uptake of proteins
ONI09_RS00210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ONI09_RS00220	COG0776	regulation of translation
ONI09_RS00235	COG0495	leucyl-tRNA aminoacylation
ONI09_RS00250	COG2801	Transposase and inactivated derivatives
ONI09_RS00255	COG2801	Transposase and inactivated derivatives
ONI09_RS00265	COG2963	transposase activity
ONI09_RS00270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ONI09_RS00295	COG3827	peptidoglycan binding
ONI09_RS00300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ONI09_RS00310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ONI09_RS00345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ONI09_RS00350	COG1121	(ABC) transporter
ONI09_RS00365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ONI09_RS00370	COG1530	ribonuclease E activity
ONI09_RS00385	COG0626	cystathionine gamma-synthase activity
ONI09_RS00420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ONI09_RS00440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ONI09_RS00445	COG0670	Belongs to the BI1 family
ONI09_RS00450	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ONI09_RS00500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ONI09_RS00510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ONI09_RS00515	COG0259	pyridoxamine-phosphate oxidase activity
ONI09_RS00525	COG2333	competence protein COMEC
ONI09_RS00525	COG0658	competence protein
ONI09_RS00540	COG0564	pseudouridine synthase activity
ONI09_RS00565	COG0126	phosphoglycerate kinase activity
ONI09_RS00580	COG2070	2-Nitropropane dioxygenase
ONI09_RS00595	COG3451	type IV secretory pathway VirB4
ONI09_RS00620	COG0508	dehydrogenase complex catalyzes the overall conversion of
ONI09_RS00635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ONI09_RS00650	COG0105	UTP biosynthetic process
ONI09_RS00680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ONI09_RS00690	COG0142	geranyltranstransferase activity
ONI09_RS00695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ONI09_RS00700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ONI09_RS00715	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ONI09_RS00730	COG0723	plastoquinol--plastocyanin reductase activity
ONI09_RS00750	COG0492	ferredoxin-NADP+ reductase activity
ONI09_RS00760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ONI09_RS00765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ONI09_RS00775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ONI09_RS00780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ONI09_RS00785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ONI09_RS00830	COG1007	ATP synthesis coupled electron transport
ONI09_RS00835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ONI09_RS00840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ONI09_RS00845	COG0713	ATP synthesis coupled electron transport
ONI09_RS00850	COG0839	Belongs to the complex I subunit 6 family
ONI09_RS00870	COG0527	aspartate kinase activity
ONI09_RS00890	COG0531	amino acid
ONI09_RS00900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ONI09_RS00910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ONI09_RS00915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ONI09_RS00920	COG3842	ATPase activity
ONI09_RS00940	COG1104	cysteine desulfurase activity
ONI09_RS00950	COG0312	modulator of DNA gyrase
ONI09_RS00980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ONI09_RS00980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ONI09_RS00985	COG2801	Transposase and inactivated derivatives
ONI09_RS00990	COG2801	Transposase and inactivated derivatives
ONI09_RS01000	COG2963	transposase activity
ONI09_RS01025	COG0006	proline dipeptidase activity
ONI09_RS01050	COG4695	Portal protein
ONI09_RS01065	COG0321	lipoyl(octanoyl) transferase activity
ONI09_RS01080	COG0047	phosphoribosylformylglycinamidine synthase activity
ONI09_RS01105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ONI09_RS01120	COG1253	flavin adenine dinucleotide binding
ONI09_RS01130	COG0436	Aminotransferase
ONI09_RS01165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ONI09_RS01200	COG1230	cation diffusion facilitator family transporter
ONI09_RS01210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ONI09_RS01215	COG1115	amino acid carrier protein
ONI09_RS01220	COG1115	amino acid carrier protein
ONI09_RS01225	COG1183	phosphatidylcholine synthase activity
ONI09_RS01235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ONI09_RS01240	COG0484	heat shock protein binding
ONI09_RS01245	COG0285	dihydrofolate synthase activity
ONI09_RS01260	COG2867	negative regulation of translational initiation
ONI09_RS01295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ONI09_RS01300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ONI09_RS01320	COG0142	geranyltranstransferase activity
ONI09_RS01340	COG3474	cytochrome
ONI09_RS01365	COG0736	holo-[acyl-carrier-protein] synthase activity
ONI09_RS01400	COG0009	L-threonylcarbamoyladenylate synthase
ONI09_RS01420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ONI09_RS01465	COG0330	HflC and HflK could
ONI09_RS01510	COG0556	nucleotide-excision repair
ONI09_RS01530	COG4235	cytochrome complex assembly
ONI09_RS01530	COG3088	subunit of a heme lyase
ONI09_RS01550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ONI09_RS01565	COG0742	ribosomal rna small subunit methyltransferase
ONI09_RS01575	COG3704	protein secretion by the type IV secretion system
ONI09_RS01575	COG0419	ATPase involved in DNA repair
ONI09_RS01580	COG3704	protein secretion by the type IV secretion system
ONI09_RS01580	COG1340	protein secretion by the type IV secretion system
ONI09_RS01585	COG3704	protein secretion by the type IV secretion system
ONI09_RS01590	COG3704	protein secretion by the type IV secretion system
ONI09_RS01595	COG3451	type IV secretory pathway VirB4
ONI09_RS01605	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ONI09_RS01620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ONI09_RS01660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ONI09_RS01665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ONI09_RS01670	COG0254	rRNA binding
ONI09_RS01675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ONI09_RS01760	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ONI09_RS01770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ONI09_RS01770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ONI09_RS01790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ONI09_RS01795	COG0552	protein localization to endoplasmic reticulum
ONI09_RS01800	COG0822	iron-sulfur transferase activity
ONI09_RS01805	COG0316	Belongs to the HesB IscA family
ONI09_RS01820	COG0681	Belongs to the peptidase S26 family
ONI09_RS01830	COG1840	ABC-type Fe3 transport system, periplasmic component
ONI09_RS01870	COG0084	hydrolase, TatD family'
ONI09_RS01880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ONI09_RS01890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ONI09_RS01910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ONI09_RS01915	COG1090	epimerase
ONI09_RS01930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ONI09_RS01940	COG1054	Belongs to the UPF0176 family
ONI09_RS01950	COG1178	ABC-type Fe3 transport system permease component
ONI09_RS01965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ONI09_RS01970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ONI09_RS01970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ONI09_RS01975	COG0628	permease
ONI09_RS01985	COG4974	Belongs to the 'phage' integrase family
ONI09_RS02000	COG0372	Belongs to the citrate synthase family
ONI09_RS02025	COG2255	four-way junction helicase activity
ONI09_RS02040	COG2094	Belongs to the DNA glycosylase MPG family
ONI09_RS02045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ONI09_RS02050	COG0772	Belongs to the SEDS family
ONI09_RS02055	COG0651	ATP synthesis coupled electron transport
ONI09_RS02080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ONI09_RS02085	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ONI09_RS02095	COG1160	GTP binding
ONI09_RS02120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ONI09_RS02125	COG0539	negative regulation of cytoplasmic translation
ONI09_RS02130	COG0776	regulation of translation
ONI09_RS02145	COG0750	zinc metalloprotease
ONI09_RS02165	COG0543	2 iron, 2 sulfur cluster binding
ONI09_RS02165	COG0493	'glutamate synthase
ONI09_RS02175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ONI09_RS02185	COG0124	histidyl-tRNA synthetase
ONI09_RS02195	COG0484	heat shock protein binding
ONI09_RS02210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ONI09_RS02215	COG2857	Cytochrome c1
ONI09_RS02215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ONI09_RS02225	COG0101	tRNA pseudouridine synthase activity
ONI09_RS02240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ONI09_RS02270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ONI09_RS02285	COG0473	3-isopropylmalate dehydrogenase activity
ONI09_RS02290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ONI09_RS02295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ONI09_RS02310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ONI09_RS02320	COG0359	binds to the 23S rRNA
ONI09_RS02330	COG0360	Binds together with S18 to 16S ribosomal RNA
ONI09_RS02345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ONI09_RS02355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ONI09_RS02360	COG0629	single-stranded DNA binding
ONI09_RS02415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ONI09_RS02425	COG0612	Peptidase, M16
ONI09_RS02430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ONI09_RS02435	COG0196	riboflavin kinase activity
ONI09_RS02450	COG0450	alkyl hydroperoxide reductase
ONI09_RS02465	COG4974	Belongs to the 'phage' integrase family
ONI09_RS02470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ONI09_RS02515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ONI09_RS02520	COG1294	oxidase, subunit
ONI09_RS02525	COG1271	oxidase subunit
ONI09_RS02545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ONI09_RS02550	COG0612	Peptidase, M16
ONI09_RS02560	COG0343	queuine tRNA-ribosyltransferase activity
ONI09_RS02565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ONI09_RS02590	COG0745	RESPONSE REGULATOR receiver
ONI09_RS02600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ONI09_RS02615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ONI09_RS02645	COG0606	chelatase, subunit chli
ONI09_RS02655	COG0768	penicillin binding
ONI09_RS02680	COG2171	N-acyltransferase activity
ONI09_RS02690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ONI09_RS02700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ONI09_RS02700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ONI09_RS02705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ONI09_RS02710	COG0316	Belongs to the HesB IscA family
ONI09_RS02720	COG2945	thiolester hydrolase activity
ONI09_RS02725	COG1104	cysteine desulfurase activity
ONI09_RS02740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ONI09_RS02765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ONI09_RS02775	COG3344	reverse transcriptase
ONI09_RS02800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ONI09_RS02800	COG0574	Belongs to the PEP-utilizing enzyme family
ONI09_RS02810	COG1494	fructose-1,6-bisphosphatase
ONI09_RS02835	COG0505	Belongs to the CarA family
ONI09_RS02850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ONI09_RS02860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ONI09_RS02875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ONI09_RS02890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ONI09_RS02925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ONI09_RS02935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ONI09_RS02945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ONI09_RS02955	COG0201	protein transport
ONI09_RS02965	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ONI09_RS02975	COG0202	RNA polymerase activity
ONI09_RS02985	COG0792	nuclease activity
ONI09_RS02990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ONI09_RS03000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ONI09_RS03005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ONI09_RS03005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ONI09_RS03025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ONI09_RS03035	COG2801	Transposase and inactivated derivatives
ONI09_RS03040	COG2801	Transposase and inactivated derivatives
ONI09_RS03065	COG3344	reverse transcriptase
ONI09_RS03150	COG3344	reverse transcriptase
ONI09_RS03180	COG3621	Patatin-like phospholipase
ONI09_RS03270	COG3621	Patatin-like phospholipase
ONI09_RS03435	COG4804	nuclease activity
ONI09_RS03485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ONI09_RS03490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ONI09_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ONI09_RS03515	COG1132	(ABC) transporter
ONI09_RS03540	COG0697	spore germination
ONI09_RS03560	COG0666	response to abiotic stimulus
ONI09_RS03570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ONI09_RS03585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ONI09_RS03590	COG2003	Belongs to the UPF0758 family
ONI09_RS03655	COG3344	reverse transcriptase
ONI09_RS03670	COG0114	fumarate hydratase activity
ONI09_RS03690	COG0281	malic enzyme
ONI09_RS03690	COG0280	phosphate acetyltransferase
ONI09_RS03695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ONI09_RS03705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ONI09_RS03725	COG0739	heme binding
ONI09_RS03760	COG0022	dehydrogenase e1 component
ONI09_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
ONI09_RS03765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ONI09_RS03775	COG0477	Major facilitator Superfamily
ONI09_RS03795	COG0590	tRNA wobble adenosine to inosine editing
ONI09_RS03800	COG0504	CTP synthase activity
ONI09_RS03820	COG0525	valine-tRNA ligase activity
ONI09_RS03835	COG0284	orotidine-5'-phosphate decarboxylase activity
ONI09_RS03865	COG1126	abc transporter atp-binding protein
ONI09_RS03870	COG0765	amino acid transport
ONI09_RS03875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ONI09_RS03880	COG1438	arginine binding
ONI09_RS03885	COG0805	protein transport
ONI09_RS03925	COG0012	GTP binding
ONI09_RS03945	COG0194	GDP metabolic process
ONI09_RS03970	COG1053	succinate dehydrogenase
ONI09_RS03975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ONI09_RS03985	COG4770	biotin carboxylase activity
ONI09_RS04015	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ONI09_RS04020	COG0356	it plays a direct role in the translocation of protons across the membrane
ONI09_RS04030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ONI09_RS04030	COG0072	phenylalanine-tRNA ligase activity
ONI09_RS04040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ONI09_RS04050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ONI09_RS04060	COG1981	membrane
ONI09_RS04065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ONI09_RS04070	COG0564	pseudouridine synthase activity
ONI09_RS04075	COG0477	Major facilitator Superfamily
ONI09_RS04090	COG4133	protoheme IX ABC transporter activity
ONI09_RS04115	COG0018	arginyl-trna synthetase
ONI09_RS04125	COG1132	(ABC) transporter
ONI09_RS04140	COG2226	methyltransferase
ONI09_RS04145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ONI09_RS04150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ONI09_RS04175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ONI09_RS04200	COG2814	Major facilitator Superfamily
ONI09_RS04250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ONI09_RS04255	COG2239	Acts as a magnesium transporter
ONI09_RS04270	COG2801	Transposase and inactivated derivatives
ONI09_RS04275	COG2801	Transposase and inactivated derivatives
ONI09_RS04285	COG2963	transposase activity
ONI09_RS04295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ONI09_RS04315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ONI09_RS04330	COG1074	ATP-dependent DNA helicase activity
ONI09_RS04340	COG2003	Belongs to the UPF0758 family
ONI09_RS04350	COG1714	RDD family
ONI09_RS04360	COG0305	Participates in initiation and elongation during chromosome replication
ONI09_RS04375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ONI09_RS04385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ONI09_RS04395	COG0358	DNA primase activity
ONI09_RS04400	COG3177	Filamentation induced by cAMP protein fic
ONI09_RS04415	COG2801	Transposase and inactivated derivatives
ONI09_RS04445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ONI09_RS04500	COG1115	amino acid carrier protein
ONI09_RS04535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ONI09_RS04565	COG0544	peptidyl-prolyl cis-trans isomerase activity
ONI09_RS04575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ONI09_RS04580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ONI09_RS04595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ONI09_RS04605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ONI09_RS04620	COG0354	folic acid binding
ONI09_RS04625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ONI09_RS04630	COG0459	protein refolding
ONI09_RS04635	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ONI09_RS04635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ONI09_RS04650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ONI09_RS04655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ONI09_RS04665	COG2801	Transposase and inactivated derivatives
ONI09_RS04760	COG4804	nuclease activity
ONI09_RS04955	COG3344	reverse transcriptase
ONI09_RS04975	COG0148	phosphopyruvate hydratase activity
ONI09_RS04980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ONI09_RS05005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ONI09_RS05025	COG2801	Transposase and inactivated derivatives
ONI09_RS05030	COG2801	Transposase and inactivated derivatives
ONI09_RS05050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ONI09_RS05060	COG0575	Belongs to the CDS family
ONI09_RS05080	COG0528	UMP kinase activity
ONI09_RS05090	COG0052	Belongs to the universal ribosomal protein uS2 family
ONI09_RS05100	COG1862	Preprotein translocase
ONI09_RS05135	COG0508	dehydrogenase complex catalyzes the overall conversion of
ONI09_RS05155	COG0653	protein targeting
ONI09_RS05185	COG2801	Transposase and inactivated derivatives
ONI09_RS05200	COG0163	prenyltransferase activity
ONI09_RS05205	COG3750	Belongs to the UPF0335 family
ONI09_RS05210	COG4536	flavin adenine dinucleotide binding
ONI09_RS05215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ONI09_RS05220	COG0649	NAD binding
ONI09_RS05240	COG1322	Protein conserved in bacteria
ONI09_RS05270	COG2814	Major facilitator Superfamily
ONI09_RS05280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ONI09_RS05285	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ONI09_RS05290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ONI09_RS05295	COG0756	dUTP diphosphatase activity
ONI09_RS05330	COG3577	Aspartyl protease
ONI09_RS05355	COG1138	Cytochrome C-type biogenesis protein
ONI09_RS05375	COG1301	dicarboxylic acid transport
ONI09_RS05380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ONI09_RS05385	COG1217	gtp-binding protein TYPA
ONI09_RS05400	COG0542	response to heat
ONI09_RS05405	COG2902	Dehydrogenase
ONI09_RS05425	COG4804	nuclease activity
ONI09_RS05460	COG0235	Class ii aldolase
ONI09_RS05480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ONI09_RS05490	COG0573	inorganic phosphate transmembrane transporter activity
ONI09_RS05525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ONI09_RS05525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ONI09_RS05535	COG1253	flavin adenine dinucleotide binding
ONI09_RS05555	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ONI09_RS05560	COG0237	dephospho-CoA kinase activity
ONI09_RS05580	COG2801	Transposase and inactivated derivatives
ONI09_RS05605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ONI09_RS05610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ONI09_RS05645	COG0149	triose-phosphate isomerase activity
ONI09_RS05650	COG0758	DNA mediated transformation
ONI09_RS05655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ONI09_RS05670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ONI09_RS05675	COG1686	Belongs to the peptidase S11 family
ONI09_RS05700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ONI09_RS05715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ONI09_RS05740	COG0187	DNA topoisomerase II activity
ONI09_RS05755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ONI09_RS05820	COG0307	riboflavin synthase, alpha
ONI09_RS05830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ONI09_RS05835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ONI09_RS05845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ONI09_RS05855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ONI09_RS05860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ONI09_RS05870	COG1845	cytochrome c oxidase, subunit III
ONI09_RS05880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ONI09_RS05890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ONI09_RS05910	COG0215	cysteine-tRNA ligase activity
ONI09_RS05915	COG3932	Exopolysaccharide synthesis, ExoD
ONI09_RS05925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ONI09_RS05930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ONI09_RS05940	COG0322	excinuclease ABC activity
ONI09_RS05950	COG0752	glycyl-tRNA synthetase alpha subunit
ONI09_RS05960	COG0113	porphobilinogen synthase activity
ONI09_RS05965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ONI09_RS05970	COG1034	ATP synthesis coupled electron transport
ONI09_RS05985	COG1573	uracil-dna glycosylase
ONI09_RS05990	COG0242	peptide deformylase activity
ONI09_RS05995	COG0849	cell division
ONI09_RS06000	COG0024	Methionine aminopeptidase
ONI09_RS06005	COG0477	Major facilitator Superfamily
ONI09_RS06010	COG0275	rRNA processing
ONI09_RS06045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ONI09_RS06055	COG0489	protein tyrosine kinase activity
ONI09_RS06070	COG2963	transposase activity
ONI09_RS06080	COG2801	Transposase and inactivated derivatives
ONI09_RS06085	COG2801	Transposase and inactivated derivatives
ONI09_RS06130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ONI09_RS06135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ONI09_RS06140	COG1185	polyribonucleotide nucleotidyltransferase activity
ONI09_RS06170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ONI09_RS06220	COG1268	BioY protein
ONI09_RS06225	COG0778	Nitroreductase
ONI09_RS06240	COG0045	succinate-CoA ligase (ADP-forming) activity
ONI09_RS06255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ONI09_RS06290	COG1475	DNA binding
ONI09_RS06310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ONI09_RS06330	COG4591	ABC-type transport system involved in lipoprotein release permease component
ONI09_RS06345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ONI09_RS06350	COG0312	modulator of DNA gyrase
ONI09_RS06355	COG1278	Cold shock
ONI09_RS06360	COG0513	Belongs to the DEAD box helicase family
ONI09_RS06375	COG1830	Aldolase
ONI09_RS06385	COG0167	dihydroorotate dehydrogenase activity
ONI09_RS06405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ONI09_RS06440	COG3346	SURF1 family
ONI09_RS06455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ONI09_RS06465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ONI09_RS06475	COG2885	chlorophyll binding
ONI09_RS06500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ONI09_RS06510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ONI09_RS06515	COG0543	2 iron, 2 sulfur cluster binding
ONI09_RS06515	COG0493	'glutamate synthase
ONI09_RS06530	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ONI09_RS06545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ONI09_RS06560	COG0326	Molecular chaperone. Has ATPase activity
ONI09_RS06575	COG0156	8-amino-7-oxononanoate synthase activity
ONI09_RS06585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ONI09_RS06595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ONI09_RS06600	COG2202	Pas domain
ONI09_RS06600	COG2205	protein histidine kinase activity
ONI09_RS06605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ONI09_RS06610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ONI09_RS06630	COG1295	ribonuclease BN
ONI09_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
ONI09_RS06645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ONI09_RS06675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ONI09_RS06680	COG1006	Multisubunit Na H antiporter MnhC subunit
ONI09_RS06690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ONI09_RS06690	COG2111	Na H antiporter
ONI09_RS06715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ONI09_RS06725	COG0567	Dehydrogenase, E1 component
ONI09_RS06755	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ONI09_RS06765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ONI09_RS06770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ONI09_RS06775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ONI09_RS06785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ONI09_RS06795	COG0174	glutamine synthetase