locus-tag	class	description
WHA_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WHA_RS00025	COG3736	Type IV secretory pathway, component VirB8
WHA_RS00040	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WHA_RS00045	COG3505	Type IV secretory pathway VirD4
WHA_RS00055	COG2890	protein-(glutamine-N5) methyltransferase activity
WHA_RS00060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WHA_RS00075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WHA_RS00090	COG0250	Participates in transcription elongation, termination and antitermination
WHA_RS00095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WHA_RS00100	COG0081	regulation of translation
WHA_RS00105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WHA_RS00110	COG0222	ribosome binding
WHA_RS00115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WHA_RS00115	COG0085	RNA polymerase activity
WHA_RS00120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WHA_RS00130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WHA_RS00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WHA_RS00160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WHA_RS00165	COG0823	Involved in the tonB-independent uptake of proteins
WHA_RS00195	COG3547	Transposase (IS116 IS110 IS902 family)
WHA_RS00215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WHA_RS00225	COG0776	regulation of translation
WHA_RS00260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WHA_RS00285	COG3827	peptidoglycan binding
WHA_RS00290	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WHA_RS00305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WHA_RS00315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WHA_RS00320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WHA_RS00330	COG1845	cytochrome c oxidase, subunit III
WHA_RS00340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WHA_RS00345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WHA_RS00360	COG3932	Exopolysaccharide synthesis, ExoD
WHA_RS00370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WHA_RS00375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WHA_RS00390	COG0751	glycine-tRNA ligase activity
WHA_RS00395	COG0752	glycyl-tRNA synthetase alpha subunit
WHA_RS00405	COG0113	porphobilinogen synthase activity
WHA_RS00410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WHA_RS00425	COG1573	uracil-dna glycosylase
WHA_RS00430	COG0242	peptide deformylase activity
WHA_RS00445	COG0024	Methionine aminopeptidase
WHA_RS00450	COG0477	Major facilitator Superfamily
WHA_RS00475	COG0193	aminoacyl-tRNA hydrolase activity
WHA_RS00485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WHA_RS00515	COG0489	protein tyrosine kinase activity
WHA_RS00580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WHA_RS00585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WHA_RS00595	COG0307	riboflavin synthase, alpha
WHA_RS00620	COG1674	ftsk spoiiie
WHA_RS00655	COG2963	transposase activity
WHA_RS00670	COG0187	DNA topoisomerase II activity
WHA_RS00680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WHA_RS00695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WHA_RS00700	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WHA_RS00700	COG0506	proline dehydrogenase activity
WHA_RS00700	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WHA_RS00725	COG1686	Belongs to the peptidase S11 family
WHA_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WHA_RS00745	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WHA_RS00750	COG0758	DNA mediated transformation
WHA_RS00755	COG0149	triose-phosphate isomerase activity
WHA_RS00780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WHA_RS00785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WHA_RS00815	COG0237	dephospho-CoA kinase activity
WHA_RS00820	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WHA_RS00845	COG1253	flavin adenine dinucleotide binding
WHA_RS00855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WHA_RS00855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WHA_RS00880	COG0573	inorganic phosphate transmembrane transporter activity
WHA_RS00885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WHA_RS00890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WHA_RS00910	COG2814	Major facilitator Superfamily
WHA_RS00915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WHA_RS00920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WHA_RS00925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WHA_RS00930	COG0756	dUTP diphosphatase activity
WHA_RS00955	COG3577	Aspartyl protease
WHA_RS00975	COG1138	Cytochrome C-type biogenesis protein
WHA_RS00990	COG1301	dicarboxylic acid transport
WHA_RS00995	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WHA_RS01000	COG1217	gtp-binding protein TYPA
WHA_RS01010	COG0542	response to heat
WHA_RS01015	COG2902	Dehydrogenase
WHA_RS01070	COG0235	Class ii aldolase
WHA_RS01080	COG1322	Protein conserved in bacteria
WHA_RS01105	COG0697	spore germination
WHA_RS01130	COG1132	(ABC) transporter
WHA_RS01150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WHA_RS01155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WHA_RS01160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WHA_RS01190	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WHA_RS01195	COG2801	Transposase and inactivated derivatives
WHA_RS01240	COG1396	sequence-specific DNA binding
WHA_RS01270	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WHA_RS01455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WHA_RS01470	COG2963	transposase activity
WHA_RS01480	COG0154	amidase activity
WHA_RS01485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WHA_RS01510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WHA_RS01525	COG0114	fumarate hydratase activity
WHA_RS01545	COG0280	phosphate acetyltransferase
WHA_RS01545	COG0281	malic enzyme
WHA_RS01550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WHA_RS01560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WHA_RS01570	COG0739	heme binding
WHA_RS01620	COG0508	dehydrogenase complex catalyzes the overall conversion of
WHA_RS01620	COG0022	dehydrogenase e1 component
WHA_RS01625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WHA_RS01630	COG0477	Major facilitator Superfamily
WHA_RS01635	COG0590	tRNA wobble adenosine to inosine editing
WHA_RS01640	COG0504	CTP synthase activity
WHA_RS01660	COG0525	valine-tRNA ligase activity
WHA_RS01680	COG0284	orotidine-5'-phosphate decarboxylase activity
WHA_RS01700	COG1126	abc transporter atp-binding protein
WHA_RS01705	COG0765	amino acid transport
WHA_RS01710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WHA_RS01715	COG1438	arginine binding
WHA_RS01720	COG0805	protein transport
WHA_RS01725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WHA_RS01745	COG0617	tRNA 3'-terminal CCA addition
WHA_RS01755	COG0012	GTP binding
WHA_RS01775	COG0194	GDP metabolic process
WHA_RS01785	COG1053	succinate dehydrogenase
WHA_RS02040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WHA_RS02070	COG0653	protein targeting
WHA_RS02090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WHA_RS02100	COG4770	biotin carboxylase activity
WHA_RS02125	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WHA_RS02130	COG0356	it plays a direct role in the translocation of protons across the membrane
WHA_RS02140	COG0072	phenylalanine-tRNA ligase activity
WHA_RS02140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WHA_RS02150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WHA_RS02160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WHA_RS02170	COG1981	membrane
WHA_RS02175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WHA_RS02180	COG0564	pseudouridine synthase activity
WHA_RS02185	COG0477	Major facilitator Superfamily
WHA_RS02200	COG4133	protoheme IX ABC transporter activity
WHA_RS02215	COG2963	transposase activity
WHA_RS02235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WHA_RS02245	COG0575	Belongs to the CDS family
WHA_RS02260	COG0528	UMP kinase activity
WHA_RS02270	COG0052	Belongs to the universal ribosomal protein uS2 family
WHA_RS02280	COG1862	Preprotein translocase
WHA_RS02295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WHA_RS02305	COG0508	dehydrogenase complex catalyzes the overall conversion of
WHA_RS02315	COG0653	protein targeting
WHA_RS02335	COG2963	transposase activity
WHA_RS02355	COG2801	Transposase and inactivated derivatives
WHA_RS02370	COG0163	prenyltransferase activity
WHA_RS02375	COG3750	Belongs to the UPF0335 family
WHA_RS02380	COG4536	flavin adenine dinucleotide binding
WHA_RS02385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WHA_RS02390	COG0649	NAD binding
WHA_RS02395	COG2963	transposase activity
WHA_RS02405	COG0018	arginyl-trna synthetase
WHA_RS02430	COG1132	(ABC) transporter
WHA_RS02445	COG2226	methyltransferase
WHA_RS02450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WHA_RS02455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WHA_RS02480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WHA_RS02490	COG2814	Major facilitator Superfamily
WHA_RS02525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WHA_RS02530	COG2239	Acts as a magnesium transporter
WHA_RS02535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WHA_RS02555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WHA_RS02575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WHA_RS02590	COG1074	ATP-dependent DNA helicase activity
WHA_RS02595	COG2003	Belongs to the UPF0758 family
WHA_RS02605	COG1714	RDD family
WHA_RS02615	COG0305	Participates in initiation and elongation during chromosome replication
WHA_RS02630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WHA_RS02640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WHA_RS02645	COG0358	DNA primase activity
WHA_RS02685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WHA_RS02740	COG1115	amino acid carrier protein
WHA_RS02755	COG0459	protein refolding
WHA_RS02765	COG0354	folic acid binding
WHA_RS02770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WHA_RS02780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WHA_RS02790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WHA_RS02795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WHA_RS02805	COG0544	peptidyl-prolyl cis-trans isomerase activity
WHA_RS02835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WHA_RS02875	COG0109	protoheme IX farnesyltransferase activity
WHA_RS02880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WHA_RS02885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WHA_RS02890	COG2963	transposase activity
WHA_RS02940	COG2963	transposase activity
WHA_RS02945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WHA_RS02970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WHA_RS02980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WHA_RS02985	COG0792	nuclease activity
WHA_RS02995	COG0202	RNA polymerase activity
WHA_RS03000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WHA_RS03005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WHA_RS03015	COG0201	protein transport
WHA_RS03025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WHA_RS03035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WHA_RS03045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WHA_RS03080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WHA_RS03095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WHA_RS03110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WHA_RS03120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WHA_RS03135	COG0505	Belongs to the CarA family
WHA_RS03150	COG1494	fructose-1,6-bisphosphatase
WHA_RS03160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WHA_RS03160	COG0574	Belongs to the PEP-utilizing enzyme family
WHA_RS03170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WHA_RS03190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WHA_RS03200	COG1104	cysteine desulfurase activity
WHA_RS03205	COG2945	thiolester hydrolase activity
WHA_RS03215	COG0316	Belongs to the HesB IscA family
WHA_RS03220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WHA_RS03225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WHA_RS03225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WHA_RS03235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WHA_RS03245	COG2171	N-acyltransferase activity
WHA_RS03270	COG0768	penicillin binding
WHA_RS03280	COG0606	chelatase, subunit chli
WHA_RS03305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WHA_RS03320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WHA_RS03330	COG0745	RESPONSE REGULATOR receiver
WHA_RS03340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WHA_RS03345	COG0343	queuine tRNA-ribosyltransferase activity
WHA_RS03355	COG0612	Peptidase, M16
WHA_RS03360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WHA_RS03365	COG1271	oxidase subunit
WHA_RS03370	COG1294	oxidase, subunit
WHA_RS03375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WHA_RS03420	COG4974	Belongs to the 'phage' integrase family
WHA_RS03435	COG0450	alkyl hydroperoxide reductase
WHA_RS03450	COG0196	riboflavin kinase activity
WHA_RS03455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WHA_RS03470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WHA_RS03525	COG0629	single-stranded DNA binding
WHA_RS03530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WHA_RS03535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WHA_RS03540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WHA_RS03550	COG0360	Binds together with S18 to 16S ribosomal RNA
WHA_RS03565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WHA_RS03580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WHA_RS03585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WHA_RS03590	COG0473	3-isopropylmalate dehydrogenase activity
WHA_RS03605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WHA_RS03625	COG0142	geranyltranstransferase activity
WHA_RS03645	COG3474	cytochrome
WHA_RS03700	COG0009	L-threonylcarbamoyladenylate synthase
WHA_RS03720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WHA_RS03765	COG0330	HflC and HflK could
WHA_RS03810	COG0556	nucleotide-excision repair
WHA_RS03840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WHA_RS03845	COG0552	protein localization to endoplasmic reticulum
WHA_RS03850	COG0822	iron-sulfur transferase activity
WHA_RS03855	COG0316	Belongs to the HesB IscA family
WHA_RS03865	COG0443	Heat shock 70 kDa protein
WHA_RS03870	COG0681	Belongs to the peptidase S26 family
WHA_RS03880	COG1840	ABC-type Fe3 transport system, periplasmic component
WHA_RS03900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WHA_RS03920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WHA_RS03935	COG0742	ribosomal rna small subunit methyltransferase
WHA_RS03945	COG0419	ATPase involved in DNA repair
WHA_RS03945	COG3704	protein secretion by the type IV secretion system
WHA_RS03950	COG3704	protein secretion by the type IV secretion system
WHA_RS03955	COG3704	protein secretion by the type IV secretion system
WHA_RS03960	COG3704	protein secretion by the type IV secretion system
WHA_RS03965	COG3451	type IV secretory pathway VirB4
WHA_RS03975	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WHA_RS03980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WHA_RS04015	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WHA_RS04020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WHA_RS04025	COG0254	rRNA binding
WHA_RS04030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WHA_RS04050	COG1185	polyribonucleotide nucleotidyltransferase activity
WHA_RS04060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WHA_RS04075	COG3088	subunit of a heme lyase
WHA_RS04075	COG4235	cytochrome complex assembly
WHA_RS04110	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
WHA_RS04145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WHA_RS04175	COG0626	cystathionine gamma-synthase activity
WHA_RS04190	COG1530	ribonuclease E activity
WHA_RS04195	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WHA_RS04205	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WHA_RS04210	COG1121	(ABC) transporter
WHA_RS04215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WHA_RS04265	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
WHA_RS04270	COG0670	Belongs to the BI1 family
WHA_RS04275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WHA_RS04285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WHA_RS04300	COG0531	amino acid
WHA_RS04310	COG0527	aspartate kinase activity
WHA_RS04340	COG0839	Belongs to the complex I subunit 6 family
WHA_RS04345	COG0713	ATP synthesis coupled electron transport
WHA_RS04350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WHA_RS04355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WHA_RS04360	COG1007	ATP synthesis coupled electron transport
WHA_RS04365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WHA_RS04365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WHA_RS04400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WHA_RS04405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WHA_RS04410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WHA_RS04415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WHA_RS04430	COG0492	ferredoxin-NADP+ reductase activity
WHA_RS04435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WHA_RS04445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WHA_RS04450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WHA_RS04455	COG1127	ABC transporter
WHA_RS04465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WHA_RS04475	COG1104	cysteine desulfurase activity
WHA_RS04480	COG0312	modulator of DNA gyrase
WHA_RS04510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WHA_RS04510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WHA_RS04520	COG2963	transposase activity
WHA_RS04545	COG0445	tRNA wobble uridine modification
WHA_RS04565	COG4695	Portal protein
WHA_RS04575	COG0321	lipoyl(octanoyl) transferase activity
WHA_RS04590	COG0047	phosphoribosylformylglycinamidine synthase activity
WHA_RS04615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WHA_RS04630	COG1253	flavin adenine dinucleotide binding
WHA_RS04640	COG0436	Aminotransferase
WHA_RS04650	COG0477	Major facilitator Superfamily
WHA_RS04660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WHA_RS04680	COG1230	cation diffusion facilitator family transporter
WHA_RS04690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WHA_RS04695	COG1115	amino acid carrier protein
WHA_RS04700	COG1115	amino acid carrier protein
WHA_RS04705	COG1183	phosphatidylcholine synthase activity
WHA_RS04715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WHA_RS04720	COG0484	heat shock protein binding
WHA_RS04725	COG0285	dihydrofolate synthase activity
WHA_RS04735	COG2867	negative regulation of translational initiation
WHA_RS04740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WHA_RS04760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WHA_RS04765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WHA_RS04785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WHA_RS04810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WHA_RS04810	COG2857	Cytochrome c1
WHA_RS04815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WHA_RS04830	COG0484	heat shock protein binding
WHA_RS04840	COG0124	histidyl-tRNA synthetase
WHA_RS04850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WHA_RS04860	COG0543	2 iron, 2 sulfur cluster binding
WHA_RS04860	COG0493	'glutamate synthase
WHA_RS04880	COG0750	zinc metalloprotease
WHA_RS04895	COG0776	regulation of translation
WHA_RS04900	COG0539	negative regulation of cytoplasmic translation
WHA_RS04905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WHA_RS04935	COG1160	GTP binding
WHA_RS04945	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WHA_RS04985	COG0651	ATP synthesis coupled electron transport
WHA_RS04990	COG0772	Belongs to the SEDS family
WHA_RS04995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WHA_RS05000	COG2094	Belongs to the DNA glycosylase MPG family
WHA_RS05010	COG2255	four-way junction helicase activity
WHA_RS05050	COG0084	hydrolase, TatD family'
WHA_RS05060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WHA_RS05070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WHA_RS05095	COG1090	epimerase
WHA_RS05110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WHA_RS05120	COG1054	Belongs to the UPF0176 family
WHA_RS05125	COG1178	ABC-type Fe3 transport system permease component
WHA_RS05140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WHA_RS05145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WHA_RS05145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WHA_RS05150	COG0628	permease
WHA_RS05160	COG4974	Belongs to the 'phage' integrase family
WHA_RS05175	COG0372	Belongs to the citrate synthase family
WHA_RS05195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WHA_RS05205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WHA_RS05210	COG0259	pyridoxamine-phosphate oxidase activity
WHA_RS05220	COG0658	competence protein
WHA_RS05220	COG2333	competence protein COMEC
WHA_RS05230	COG0564	pseudouridine synthase activity
WHA_RS05255	COG0126	phosphoglycerate kinase activity
WHA_RS05265	COG2070	2-Nitropropane dioxygenase
WHA_RS05280	COG3451	type IV secretory pathway VirB4
WHA_RS05300	COG0508	dehydrogenase complex catalyzes the overall conversion of
WHA_RS05315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WHA_RS05320	COG0105	UTP biosynthetic process
WHA_RS05330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WHA_RS05350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WHA_RS05360	COG0142	geranyltranstransferase activity
WHA_RS05365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WHA_RS05370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WHA_RS05385	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
WHA_RS05400	COG0723	plastoquinol--plastocyanin reductase activity
WHA_RS05425	COG1268	BioY protein
WHA_RS05430	COG0778	Nitroreductase
WHA_RS05445	COG0045	succinate-CoA ligase (ADP-forming) activity
WHA_RS05460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WHA_RS05490	COG1475	DNA binding
WHA_RS05515	COG2009	succinate dehydrogenase
WHA_RS05530	COG4591	ABC-type transport system involved in lipoprotein release permease component
WHA_RS05545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WHA_RS05550	COG0312	modulator of DNA gyrase
WHA_RS05555	COG1278	Cold shock
WHA_RS05560	COG0513	Belongs to the DEAD box helicase family
WHA_RS05570	COG1830	Aldolase
WHA_RS05580	COG0167	dihydroorotate dehydrogenase activity
WHA_RS05595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WHA_RS05635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WHA_RS05645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WHA_RS05655	COG2885	chlorophyll binding
WHA_RS05680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WHA_RS05695	COG0543	2 iron, 2 sulfur cluster binding
WHA_RS05695	COG0493	'glutamate synthase
WHA_RS05710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WHA_RS05725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WHA_RS05730	COG0326	Molecular chaperone. Has ATPase activity
WHA_RS05745	COG0156	8-amino-7-oxononanoate synthase activity
WHA_RS05765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WHA_RS05770	COG2205	protein histidine kinase activity
WHA_RS05770	COG2202	Pas domain
WHA_RS05775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WHA_RS05780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WHA_RS05800	COG1295	ribonuclease BN
WHA_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
WHA_RS05830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WHA_RS05835	COG1006	Multisubunit Na H antiporter MnhC subunit
WHA_RS05845	COG2111	Na H antiporter
WHA_RS05845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WHA_RS05870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WHA_RS05880	COG0567	Dehydrogenase, E1 component
WHA_RS05910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WHA_RS05915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WHA_RS05920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WHA_RS05925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WHA_RS05935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WHA_RS05945	COG0174	glutamine synthetase
WHA_RS06045	COG3547	Transposase (IS116 IS110 IS902 family)