locus-tag	class	description
ASM33_RS00010	COG4974	Belongs to the 'phage' integrase family
ASM33_RS00045	COG2801	Transposase and inactivated derivatives
ASM33_RS00045	COG3415	Transposase
ASM33_RS00050	COG1999	signal sequence binding
ASM33_RS00090	COG2902	Dehydrogenase
ASM33_RS00105	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ASM33_RS00140	COG0649	NAD binding
ASM33_RS00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASM33_RS00165	COG0612	Peptidase, M16
ASM33_RS00220	COG0651	ATP synthesis coupled electron transport
ASM33_RS00260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASM33_RS00275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASM33_RS00290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASM33_RS00295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASM33_RS00300	COG0542	response to heat
ASM33_RS00315	COG0114	fumarate hydratase activity
ASM33_RS00335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS00370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS00405	COG1268	BioY protein
ASM33_RS00445	COG0531	amino acid
ASM33_RS00465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASM33_RS00490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS00585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_RS00590	COG3621	Patatin-like phospholipase
ASM33_RS00645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS00660	COG2003	Belongs to the UPF0758 family
ASM33_RS00685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS00740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASM33_RS00750	COG5265	(ABC) transporter
ASM33_RS00780	COG2801	Transposase and inactivated derivatives
ASM33_RS00780	COG3415	Transposase
ASM33_RS00805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASM33_RS00840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASM33_RS00880	COG2003	Belongs to the UPF0758 family
ASM33_RS00890	COG1396	sequence-specific DNA binding
ASM33_RS00915	COG1396	sequence-specific DNA binding
ASM33_RS00925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASM33_RS00955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASM33_RS00970	COG0194	GDP metabolic process
ASM33_RS01010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASM33_RS01010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASM33_RS01035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASM33_RS01045	COG0723	plastoquinol--plastocyanin reductase activity
ASM33_RS01050	COG1127	ABC transporter
ASM33_RS01055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASM33_RS01060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASM33_RS01065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASM33_RS01070	COG0489	protein tyrosine kinase activity
ASM33_RS01085	COG2239	Acts as a magnesium transporter
ASM33_RS01095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASM33_RS01100	COG1115	amino acid carrier protein
ASM33_RS01105	COG1115	amino acid carrier protein
ASM33_RS01115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASM33_RS01125	COG1230	cation diffusion facilitator family transporter
ASM33_RS01135	COG2003	Belongs to the UPF0758 family
ASM33_RS01140	COG1840	ABC-type Fe3 transport system, periplasmic component
ASM33_RS01145	COG3385	transposase activity
ASM33_RS01155	COG3415	Transposase
ASM33_RS01155	COG2801	Transposase and inactivated derivatives
ASM33_RS01165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASM33_RS01170	COG0254	rRNA binding
ASM33_RS01175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASM33_RS01180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASM33_RS01225	COG1322	Protein conserved in bacteria
ASM33_RS01250	COG0371	Dehydrogenase
ASM33_RS01265	COG2801	Transposase and inactivated derivatives
ASM33_RS01265	COG3415	Transposase
ASM33_RS01270	COG0726	polysaccharide deacetylase
ASM33_RS01275	COG0768	penicillin binding
ASM33_RS01285	COG3415	Transposase
ASM33_RS01285	COG2801	Transposase and inactivated derivatives
ASM33_RS01290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASM33_RS01295	COG1121	(ABC) transporter
ASM33_RS01320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASM33_RS01330	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ASM33_RS01345	COG3736	Type IV secretory pathway, component VirB8
ASM33_RS01385	COG2801	Transposase and inactivated derivatives
ASM33_RS01385	COG3415	Transposase
ASM33_RS01400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASM33_RS01405	COG0493	'glutamate synthase
ASM33_RS01405	COG0543	2 iron, 2 sulfur cluster binding
ASM33_RS01455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASM33_RS01495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASM33_RS01515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASM33_RS01525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASM33_RS01530	COG3385	transposase activity
ASM33_RS01545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASM33_RS01550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASM33_RS01555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASM33_RS01560	COG0792	nuclease activity
ASM33_RS01570	COG0202	RNA polymerase activity
ASM33_RS01580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASM33_RS01590	COG0201	protein transport
ASM33_RS01600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASM33_RS01610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASM33_RS01620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASM33_RS01655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASM33_RS01670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASM33_RS01675	COG0089	rRNA binding
ASM33_RS01685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASM33_RS01695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASM33_RS01710	COG0505	Belongs to the CarA family
ASM33_RS01725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASM33_RS01735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASM33_RS01740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASM33_RS01745	COG0573	inorganic phosphate transmembrane transporter activity
ASM33_RS01750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASM33_RS01755	COG0594	ribonuclease P activity
ASM33_RS01770	COG0459	protein refolding
ASM33_RS01780	COG0354	folic acid binding
ASM33_RS01785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASM33_RS01855	COG0861	Integral membrane protein TerC family
ASM33_RS01860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASM33_RS01865	COG0539	negative regulation of cytoplasmic translation
ASM33_RS01870	COG0776	regulation of translation
ASM33_RS01890	COG0750	zinc metalloprotease
ASM33_RS01905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASM33_RS01915	COG0156	8-amino-7-oxononanoate synthase activity
ASM33_RS01930	COG0326	Molecular chaperone. Has ATPase activity
ASM33_RS01935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASM33_RS01935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASM33_RS01940	COG0552	protein localization to endoplasmic reticulum
ASM33_RS01950	COG4770	biotin carboxylase activity
ASM33_RS02030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASM33_RS02035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASM33_RS02040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASM33_RS02055	COG3385	transposase activity
ASM33_RS02080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASM33_RS02100	COG0484	heat shock protein binding
ASM33_RS02105	COG3385	transposase activity
ASM33_RS02110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASM33_RS02110	COG0085	RNA polymerase activity
ASM33_RS02115	COG0222	ribosome binding
ASM33_RS02120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASM33_RS02125	COG0081	regulation of translation
ASM33_RS02130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASM33_RS02150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASM33_RS02175	COG1115	amino acid carrier protein
ASM33_RS02190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ASM33_RS02200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASM33_RS02205	COG3038	cytochrome b561
ASM33_RS02210	COG2070	2-Nitropropane dioxygenase
ASM33_RS02225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASM33_RS02230	COG1530	ribonuclease E activity
ASM33_RS02245	COG0666	response to abiotic stimulus
ASM33_RS02255	COG0424	maF-like protein
ASM33_RS02275	COG0321	lipoyl(octanoyl) transferase activity
ASM33_RS02290	COG0629	single-stranded DNA binding
ASM33_RS02295	COG0698	ribose 5-phosphate isomerase
ASM33_RS02300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASM33_RS02310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASM33_RS02330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASM33_RS02335	COG0237	dephospho-CoA kinase activity
ASM33_RS02345	COG2885	chlorophyll binding
ASM33_RS02370	COG0316	Belongs to the HesB IscA family
ASM33_RS02375	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASM33_RS02380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASM33_RS02380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASM33_RS02385	COG3385	transposase activity
ASM33_RS02395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASM33_RS02405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASM33_RS02425	COG3415	Transposase
ASM33_RS02425	COG2801	Transposase and inactivated derivatives
ASM33_RS02430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASM33_RS02435	COG2202	Pas domain
ASM33_RS02435	COG2205	protein histidine kinase activity
ASM33_RS02460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASM33_RS02465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASM33_RS02475	COG0312	modulator of DNA gyrase
ASM33_RS02510	COG2801	Transposase and inactivated derivatives
ASM33_RS02510	COG3415	Transposase
ASM33_RS02530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASM33_RS02570	COG0776	regulation of translation
ASM33_RS02585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASM33_RS02590	COG3415	Transposase
ASM33_RS02590	COG2801	Transposase and inactivated derivatives
ASM33_RS02630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASM33_RS02650	COG2171	N-acyltransferase activity
ASM33_RS02680	COG1301	dicarboxylic acid transport
ASM33_RS02685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASM33_RS02695	COG2226	methyltransferase
ASM33_RS02700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASM33_RS02720	COG0581	inorganic phosphate transmembrane transporter activity
ASM33_RS02725	COG0047	phosphoribosylformylglycinamidine synthase activity
ASM33_RS02755	COG0752	glycyl-tRNA synthetase alpha subunit
ASM33_RS02760	COG0751	glycine-tRNA ligase activity
ASM33_RS02765	COG0322	excinuclease ABC activity
ASM33_RS02785	COG2801	Transposase and inactivated derivatives
ASM33_RS02785	COG3415	Transposase
ASM33_RS02800	COG4232	protein-disulfide reductase activity
ASM33_RS02810	COG3385	transposase activity
ASM33_RS02815	COG0154	amidase activity
ASM33_RS02825	COG2814	Major facilitator Superfamily
ASM33_RS02835	COG1178	ABC-type Fe3 transport system permease component
ASM33_RS02850	COG0543	2 iron, 2 sulfur cluster binding
ASM33_RS02850	COG0493	'glutamate synthase
ASM33_RS02855	COG0564	pseudouridine synthase activity
ASM33_RS02880	COG1253	flavin adenine dinucleotide binding
ASM33_RS02895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASM33_RS02905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASM33_RS02915	COG0285	dihydrofolate synthase activity
ASM33_RS02925	COG2094	Belongs to the DNA glycosylase MPG family
ASM33_RS02940	COG0196	riboflavin kinase activity
ASM33_RS02945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASM33_RS02950	COG0612	Peptidase, M16
ASM33_RS02960	COG0823	Involved in the tonB-independent uptake of proteins
ASM33_RS02975	COG2945	thiolester hydrolase activity
ASM33_RS02980	COG1104	cysteine desulfurase activity
ASM33_RS03000	COG0670	Belongs to the BI1 family
ASM33_RS03005	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ASM33_RS03010	COG4536	flavin adenine dinucleotide binding
ASM33_RS03015	COG3750	Belongs to the UPF0335 family
ASM33_RS03020	COG0163	prenyltransferase activity
ASM33_RS03025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASM33_RS03055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASM33_RS03060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASM33_RS03070	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASM33_RS03100	COG0477	Major facilitator Superfamily
ASM33_RS03120	COG0728	peptidoglycan biosynthetic process
ASM33_RS03125	COG0436	Aminotransferase
ASM33_RS03130	COG3385	transposase activity
ASM33_RS03145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASM33_RS03150	COG3415	Transposase
ASM33_RS03150	COG2801	Transposase and inactivated derivatives
ASM33_RS03155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASM33_RS03175	COG3415	Transposase
ASM33_RS03175	COG2801	Transposase and inactivated derivatives
ASM33_RS03185	COG3451	type IV secretory pathway VirB4
ASM33_RS03195	COG1040	competence protein
ASM33_RS03210	COG0626	cystathionine gamma-synthase activity
ASM33_RS03215	COG0271	Belongs to the BolA IbaG family
ASM33_RS03235	COG0653	protein targeting
ASM33_RS03285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASM33_RS03290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASM33_RS03295	COG0666	response to abiotic stimulus
ASM33_RS03335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASM33_RS03365	COG0101	tRNA pseudouridine synthase activity
ASM33_RS03370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_RS03380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASM33_RS03385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASM33_RS03415	COG4122	O-methyltransferase activity
ASM33_RS03435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASM33_RS03440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASM33_RS03445	COG1396	sequence-specific DNA binding
ASM33_RS03465	COG0756	dUTP diphosphatase activity
ASM33_RS03470	COG2801	Transposase and inactivated derivatives
ASM33_RS03470	COG3415	Transposase
ASM33_RS03475	COG2255	four-way junction helicase activity
ASM33_RS03480	COG0632	four-way junction helicase activity
ASM33_RS03495	COG2009	succinate dehydrogenase
ASM33_RS03500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASM33_RS03510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASM33_RS03535	COG1138	Cytochrome C-type biogenesis protein
ASM33_RS03545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASM33_RS03555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASM33_RS03570	COG0772	Belongs to the SEDS family
ASM33_RS03590	COG0574	Belongs to the PEP-utilizing enzyme family
ASM33_RS03590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASM33_RS03600	COG2801	Transposase and inactivated derivatives
ASM33_RS03600	COG3415	Transposase
ASM33_RS03625	COG4133	protoheme IX ABC transporter activity
ASM33_RS03640	COG0084	hydrolase, TatD family'
ASM33_RS03645	COG3385	transposase activity
ASM33_RS03665	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASM33_RS03685	COG0742	ribosomal rna small subunit methyltransferase
ASM33_RS03695	COG0419	ATPase involved in DNA repair
ASM33_RS03695	COG3704	protein secretion by the type IV secretion system
ASM33_RS03710	COG3704	protein secretion by the type IV secretion system
ASM33_RS03715	COG3451	type IV secretory pathway VirB4
ASM33_RS03725	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ASM33_RS03735	COG0681	Belongs to the peptidase S26 family
ASM33_RS03740	COG2076	Multidrug Resistance protein
ASM33_RS03745	COG2076	Multidrug Resistance protein
ASM33_RS03760	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASM33_RS03765	COG0113	porphobilinogen synthase activity
ASM33_RS03775	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASM33_RS03785	COG1034	ATP synthesis coupled electron transport
ASM33_RS03815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASM33_RS03815	COG0475	glutathione-regulated potassium exporter activity
ASM33_RS03825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASM33_RS03835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASM33_RS03845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASM33_RS03855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASM33_RS03860	COG0556	nucleotide-excision repair
ASM33_RS03880	COG1074	ATP-dependent DNA helicase activity
ASM33_RS03895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASM33_RS03915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASM33_RS03930	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_RS03950	COG0217	transcriptional regulatory protein
ASM33_RS03970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASM33_RS03985	COG0571	ribonuclease III activity
ASM33_RS03990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASM33_RS03995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASM33_RS04015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASM33_RS04040	COG0280	phosphate acetyltransferase
ASM33_RS04040	COG0281	malic enzyme
ASM33_RS04045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASM33_RS04060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASM33_RS04065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASM33_RS04080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASM33_RS04100	COG0745	RESPONSE REGULATOR receiver
ASM33_RS04135	COG0167	dihydroorotate dehydrogenase activity
ASM33_RS04150	COG1053	succinate dehydrogenase
ASM33_RS04160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASM33_RS04165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASM33_RS04175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASM33_RS04185	COG0372	Belongs to the citrate synthase family
ASM33_RS04205	COG2814	Major facilitator Superfamily
ASM33_RS04225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASM33_RS04235	COG0575	Belongs to the CDS family
ASM33_RS04240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASM33_RS04255	COG0233	cytoplasmic translational termination
ASM33_RS04260	COG0528	UMP kinase activity
ASM33_RS04270	COG0052	Belongs to the universal ribosomal protein uS2 family
ASM33_RS04285	COG1845	cytochrome c oxidase, subunit III
ASM33_RS04295	COG1090	epimerase
ASM33_RS04310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASM33_RS04360	COG0330	HflC and HflK could
ASM33_RS04390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASM33_RS04395	COG0495	leucyl-tRNA aminoacylation
ASM33_RS04405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASM33_RS04410	COG1006	Multisubunit Na H antiporter MnhC subunit
ASM33_RS04435	COG1758	RNA polymerase activity
ASM33_RS04460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASM33_RS04465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASM33_RS04480	COG3415	Transposase
ASM33_RS04480	COG2801	Transposase and inactivated derivatives
ASM33_RS04485	COG3088	subunit of a heme lyase
ASM33_RS04500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASM33_RS04515	COG0307	riboflavin synthase, alpha
ASM33_RS04530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASM33_RS04535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASM33_RS04545	COG3474	cytochrome
ASM33_RS04555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASM33_RS04585	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASM33_RS04600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASM33_RS04605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASM33_RS04615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASM33_RS04625	COG4221	oxidoreductase activity
ASM33_RS04630	COG1295	ribonuclease BN
ASM33_RS04635	COG0138	bifunctional purine biosynthesis protein purh
ASM33_RS04650	COG2801	Transposase and inactivated derivatives
ASM33_RS04650	COG3415	Transposase
ASM33_RS04655	COG3385	transposase activity
ASM33_RS04675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASM33_RS04680	COG0316	Belongs to the HesB IscA family
ASM33_RS04700	COG0360	Binds together with S18 to 16S ribosomal RNA
ASM33_RS04710	COG0359	binds to the 23S rRNA
ASM33_RS04715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASM33_RS04730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASM33_RS04745	COG0839	Belongs to the complex I subunit 6 family
ASM33_RS04750	COG0713	ATP synthesis coupled electron transport
ASM33_RS04755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASM33_RS04760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_RS04765	COG1007	ATP synthesis coupled electron transport
ASM33_RS04815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASM33_RS04820	COG0758	DNA mediated transformation
ASM33_RS04825	COG0006	proline dipeptidase activity
ASM33_RS04835	COG0305	Participates in initiation and elongation during chromosome replication
ASM33_RS04870	COG3328	transposase activity
ASM33_RS04890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS05045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS05160	COG3621	Patatin-like phospholipase
ASM33_RS05210	COG1396	sequence-specific DNA binding
ASM33_RS05220	COG2003	Belongs to the UPF0758 family
ASM33_RS05265	COG2003	Belongs to the UPF0758 family
ASM33_RS05315	COG3621	Patatin-like phospholipase
ASM33_RS05320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_RS05485	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_RS05510	COG4804	nuclease activity
ASM33_RS05605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS05610	COG1396	sequence-specific DNA binding
ASM33_RS05615	COG3177	Filamentation induced by cAMP protein fic
ASM33_RS05635	COG0666	response to abiotic stimulus
ASM33_RS05660	COG2003	Belongs to the UPF0758 family
ASM33_RS05675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS05780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_RS05785	COG3621	Patatin-like phospholipase
ASM33_RS05820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASM33_RS05825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASM33_RS05835	COG3577	Aspartyl protease
ASM33_RS05840	COG0187	DNA topoisomerase II activity
ASM33_RS05850	COG0473	3-isopropylmalate dehydrogenase activity
ASM33_RS05890	COG0450	alkyl hydroperoxide reductase
ASM33_RS05935	COG0343	queuine tRNA-ribosyltransferase activity
ASM33_RS05945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASM33_RS05980	COG0259	pyridoxamine-phosphate oxidase activity
ASM33_RS05985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASM33_RS06015	COG0492	ferredoxin-NADP+ reductase activity
ASM33_RS06025	COG3385	transposase activity
ASM33_RS06040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ASM33_RS06075	COG1830	Aldolase
ASM33_RS06090	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_RS06100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_RS06120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASM33_RS06125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASM33_RS06130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASM33_RS06140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASM33_RS06155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASM33_RS06175	COG3415	Transposase
ASM33_RS06175	COG2801	Transposase and inactivated derivatives
ASM33_RS06195	COG1324	tolerance protein
ASM33_RS06205	COG0275	rRNA processing
ASM33_RS06210	COG0477	Major facilitator Superfamily
ASM33_RS06215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASM33_RS06220	COG0009	L-threonylcarbamoyladenylate synthase
ASM33_RS06230	COG2890	protein-(glutamine-N5) methyltransferase activity
ASM33_RS06235	COG0477	Major facilitator Superfamily
ASM33_RS06255	COG1054	Belongs to the UPF0176 family
ASM33_RS06260	COG1573	uracil-dna glycosylase
ASM33_RS06265	COG0242	peptide deformylase activity
ASM33_RS06270	COG0849	cell division
ASM33_RS06280	COG0024	Methionine aminopeptidase
ASM33_RS06285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASM33_RS06300	COG2975	iron-sulfur cluster assembly
ASM33_RS06325	COG0012	GTP binding
ASM33_RS06350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASM33_RS06365	COG1494	fructose-1,6-bisphosphatase
ASM33_RS06370	COG3385	transposase activity
ASM33_RS06385	COG0617	tRNA 3'-terminal CCA addition
ASM33_RS06400	COG3415	Transposase
ASM33_RS06400	COG2801	Transposase and inactivated derivatives
ASM33_RS06435	COG0126	phosphoglycerate kinase activity
ASM33_RS06445	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_RS06460	COG0516	GMP reductase activity
ASM33_RS06460	COG0517	IMP dehydrogenase activity
ASM33_RS06470	COG0022	dehydrogenase e1 component
ASM33_RS06470	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_RS06490	COG3932	Exopolysaccharide synthesis, ExoD
ASM33_RS06495	COG0215	cysteine-tRNA ligase activity
ASM33_RS06535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASM33_RS06540	COG0356	it plays a direct role in the translocation of protons across the membrane
ASM33_RS06590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASM33_RS06605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASM33_RS06605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASM33_RS06620	COG1475	DNA binding
ASM33_RS06645	COG4974	Belongs to the 'phage' integrase family
ASM33_RS06670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASM33_RS06675	COG1981	membrane
ASM33_RS06700	COG0228	four-way junction DNA binding
ASM33_RS06705	COG0142	geranyltranstransferase activity
ASM33_RS06715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASM33_RS06725	COG0564	pseudouridine synthase activity
ASM33_RS06765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASM33_RS06780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASM33_RS06790	COG3415	Transposase
ASM33_RS06790	COG2801	Transposase and inactivated derivatives
ASM33_RS06800	COG0805	protein transport
ASM33_RS06805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASM33_RS06820	COG0504	CTP synthase activity
ASM33_RS06830	COG0590	tRNA wobble adenosine to inosine editing
ASM33_RS06835	COG0527	aspartate kinase activity
ASM33_RS06840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASM33_RS06845	COG3385	transposase activity
ASM33_RS06910	COG0525	valine-tRNA ligase activity
ASM33_RS06920	COG0284	orotidine-5'-phosphate decarboxylase activity
ASM33_RS06940	COG3385	transposase activity
ASM33_RS06985	COG1686	Belongs to the peptidase S11 family
ASM33_RS06990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASM33_RS07010	COG1185	polyribonucleotide nucleotidyltransferase activity
ASM33_RS07020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASM33_RS07025	COG3385	transposase activity
ASM33_RS07055	COG4695	Portal protein
ASM33_RS07065	COG0484	heat shock protein binding
ASM33_RS07075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASM33_RS07150	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASM33_RS07165	COG1450	Type ii and iii secretion system protein
ASM33_RS07195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS07210	COG2003	Belongs to the UPF0758 family
ASM33_RS07230	COG3385	transposase activity
ASM33_RS07240	COG3328	transposase activity
ASM33_RS07260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS07365	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_RS07425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS07525	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_RS07685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_RS07690	COG3621	Patatin-like phospholipase
ASM33_RS07710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASM33_RS07740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS07755	COG2003	Belongs to the UPF0758 family
ASM33_RS07785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_RS07850	COG0124	histidyl-tRNA synthetase
ASM33_RS07860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASM33_RS07880	COG1183	phosphatidylcholine synthase activity
ASM33_RS07925	COG0072	phenylalanine-tRNA ligase activity
ASM33_RS07925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASM33_RS07945	COG3385	transposase activity
ASM33_RS07960	COG1214	PFAM Peptidase M22, glycoprotease
ASM33_RS07975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ASM33_RS07985	COG1132	(ABC) transporter
ASM33_RS07990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASM33_RS08035	COG0149	triose-phosphate isomerase activity
ASM33_RS08045	COG1132	(ABC) transporter
ASM33_RS08055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASM33_RS08060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASM33_RS08085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASM33_RS08100	COG1104	cysteine desulfurase activity
ASM33_RS08125	COG0445	tRNA wobble uridine modification
ASM33_RS08145	COG2801	Transposase and inactivated derivatives
ASM33_RS08145	COG3415	Transposase
ASM33_RS08150	COG1160	GTP binding
ASM33_RS08175	COG0045	succinate-CoA ligase (ADP-forming) activity
ASM33_RS08190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASM33_RS08195	COG0567	Dehydrogenase, E1 component
ASM33_RS08230	COG1278	Cold shock
ASM33_RS08235	COG0312	modulator of DNA gyrase
ASM33_RS08240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASM33_RS08265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASM33_RS08275	COG1217	gtp-binding protein TYPA
ASM33_RS08285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASM33_RS08290	COG0628	permease