locus-tag	class	description
XAUT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XAUT_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XAUT_RS00035	COG0411	ABC transporter
XAUT_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS00050	COG1802	Transcriptional regulator
XAUT_RS00055	COG0371	Dehydrogenase
XAUT_RS00065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XAUT_RS00075	COG3454	Phosphonate metabolism
XAUT_RS00085	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
XAUT_RS00110	COG2884	Cell division ATP-binding protein ftsE
XAUT_RS00130	COG3842	ATPase activity
XAUT_RS00160	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
XAUT_RS00170	COG0501	Belongs to the peptidase M48B family
XAUT_RS00175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XAUT_RS00185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XAUT_RS00190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XAUT_RS00210	COG0683	leucine binding
XAUT_RS00245	COG0521	Mo-molybdopterin cofactor biosynthetic process
XAUT_RS00250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XAUT_RS00260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XAUT_RS00275	COG1970	mechanosensitive ion channel activity
XAUT_RS00280	COG0167	dihydroorotate dehydrogenase activity
XAUT_RS00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XAUT_RS00295	COG2205	protein histidine kinase activity
XAUT_RS00310	COG1846	Transcriptional regulator
XAUT_RS00315	COG1764	response to oxidative stress
XAUT_RS00325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XAUT_RS00330	COG1137	ATPase activity
XAUT_RS00335	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XAUT_RS00345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XAUT_RS00355	COG0129	dihydroxy-acid dehydratase activity
XAUT_RS00390	COG0756	dUTP diphosphatase activity
XAUT_RS00395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XAUT_RS00410	COG1716	ATPase activity
XAUT_RS00410	COG5001	Diguanylate cyclase
XAUT_RS00415	COG3604	Transcriptional regulator
XAUT_RS00420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XAUT_RS00425	COG0719	Fe-S assembly protein
XAUT_RS00430	COG0396	ATPase activity
XAUT_RS00435	COG0719	Fe-S assembly protein
XAUT_RS00440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XAUT_RS00445	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
XAUT_RS00455	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XAUT_RS00460	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XAUT_RS00465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XAUT_RS00480	COG5420	small protein containing a coiled-coil domain
XAUT_RS00530	COG0316	Belongs to the HesB IscA family
XAUT_RS00540	COG1104	cysteine desulfurase activity
XAUT_RS00560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XAUT_RS00580	COG5554	nitrogen fixation
XAUT_RS00600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XAUT_RS00615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XAUT_RS00625	COG3608	succinylglutamate desuccinylase aspartoacylase
XAUT_RS00625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XAUT_RS00635	COG2151	metal-sulfur cluster biosynthetic enzyme
XAUT_RS00660	COG2346	COG2346, Truncated hemoglobins
XAUT_RS00695	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XAUT_RS00700	COG0644	oxidoreductase
XAUT_RS00705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XAUT_RS00710	COG2086	electron transfer activity
XAUT_RS00715	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
XAUT_RS00720	COG4565	transcriptional regulatory protein
XAUT_RS00745	COG0316	Belongs to the HesB IscA family
XAUT_RS00765	COG0039	L-malate dehydrogenase activity
XAUT_RS00770	COG0045	succinate-CoA ligase (ADP-forming) activity
XAUT_RS00775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XAUT_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAUT_RS00800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAUT_RS00805	COG1733	regulation of RNA biosynthetic process
XAUT_RS00820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XAUT_RS00825	COG1695	Transcriptional regulator
XAUT_RS00835	COG0651	ATP synthesis coupled electron transport
XAUT_RS00840	COG0650	Formate hydrogenlyase subunit 4
XAUT_RS00850	COG0651	ATP synthesis coupled electron transport
XAUT_RS00855	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
XAUT_RS00855	COG3261	NADH dehydrogenase
XAUT_RS00860	COG3260	NADH ubiquinone oxidoreductase 20
XAUT_RS00865	COG1802	Transcriptional regulator
XAUT_RS00870	COG0246	Mannitol dehydrogenase
XAUT_RS00880	COG0765	amino acid transport
XAUT_RS00885	COG1126	abc transporter atp-binding protein
XAUT_RS00890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS00895	COG1063	alcohol dehydrogenase
XAUT_RS00900	COG2721	sulfolactate sulfo-lyase activity
XAUT_RS00905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAUT_RS00930	COG3158	transport of potassium into the cell
XAUT_RS00935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XAUT_RS00965	COG0778	Nitroreductase
XAUT_RS00970	COG1278	Cold shock
XAUT_RS00995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XAUT_RS01000	COG0573	inorganic phosphate transmembrane transporter activity
XAUT_RS01010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XAUT_RS01015	COG0704	Plays a role in the regulation of phosphate uptake
XAUT_RS01020	COG0745	RESPONSE REGULATOR receiver
XAUT_RS01035	COG0142	geranyltranstransferase activity
XAUT_RS01040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XAUT_RS01045	COG2917	probably involved in intracellular septation
XAUT_RS01050	COG1959	2 iron, 2 sulfur cluster binding
XAUT_RS01055	COG0842	Transport permease protein
XAUT_RS01060	COG1129	ABC transporter
XAUT_RS01060	COG0842	Transport permease protein
XAUT_RS01065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS01075	COG1522	sequence-specific DNA binding
XAUT_RS01130	COG2801	Transposase and inactivated derivatives
XAUT_RS01160	COG1204	response to ionizing radiation
XAUT_RS01315	COG0039	L-malate dehydrogenase activity
XAUT_RS01350	COG2855	membrane
XAUT_RS01355	COG0583	DNA-binding transcription factor activity
XAUT_RS01360	COG1271	oxidase subunit
XAUT_RS01370	COG2801	Transposase and inactivated derivatives
XAUT_RS01400	COG3549	Plasmid maintenance system killer
XAUT_RS01405	COG3093	addiction module antidote protein HigA
XAUT_RS01425	COG2203	Gaf domain
XAUT_RS01425	COG4251	negative regulation of phosphorylation
XAUT_RS01425	COG3706	GGDEF domain
XAUT_RS01425	COG5001	Diguanylate cyclase
XAUT_RS01430	COG0791	NLP P60 protein
XAUT_RS01435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XAUT_RS01445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XAUT_RS01450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XAUT_RS01465	COG1185	polyribonucleotide nucleotidyltransferase activity
XAUT_RS01470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XAUT_RS01475	COG0747	negative chemotaxis
XAUT_RS01480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XAUT_RS01485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XAUT_RS01490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XAUT_RS01505	COG0779	Required for maturation of 30S ribosomal subunits
XAUT_RS01525	COG0436	Aminotransferase
XAUT_RS01555	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XAUT_RS01585	COG0702	epimerase
XAUT_RS01595	COG3655	Transcriptional regulator
XAUT_RS01615	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XAUT_RS01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS01630	COG0657	acetylesterase activity
XAUT_RS01635	COG0583	DNA-binding transcription factor activity
XAUT_RS01640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XAUT_RS01645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XAUT_RS01650	COG1181	Belongs to the D-alanine--D-alanine ligase family
XAUT_RS01655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XAUT_RS01660	COG0849	cell division
XAUT_RS01665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XAUT_RS01675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAUT_RS01680	COG0497	DNA recombination
XAUT_RS01705	COG2226	methyltransferase
XAUT_RS01715	COG0189	ligase activity
XAUT_RS01720	COG0792	nuclease activity
XAUT_RS01725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XAUT_RS01745	COG4191	Histidine kinase
XAUT_RS01770	COG1335	isochorismatase
XAUT_RS01775	COG0443	Heat shock 70 kDa protein
XAUT_RS01785	COG0484	heat shock protein binding
XAUT_RS01800	COG3963	phosphatidate phosphatase activity
XAUT_RS01805	COG0406	alpha-ribazole phosphatase activity
XAUT_RS01810	COG0284	orotidine-5'-phosphate decarboxylase activity
XAUT_RS01825	COG0588	phosphoglycerate mutase activity
XAUT_RS01830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XAUT_RS01835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XAUT_RS01845	COG1741	Belongs to the pirin family
XAUT_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
XAUT_RS01860	COG3284	Transcriptional regulator
XAUT_RS01895	COG2205	protein histidine kinase activity
XAUT_RS01900	COG0154	amidase activity
XAUT_RS01910	COG2368	4-hydroxyphenylacetate
XAUT_RS01915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XAUT_RS01920	COG1846	Transcriptional regulator
XAUT_RS01930	COG0577	efflux transmembrane transporter activity
XAUT_RS01935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS01940	COG3321	synthase
XAUT_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS01940	COG0604	alcohol dehydrogenase
XAUT_RS01955	COG2010	Cytochrome c
XAUT_RS01965	COG2951	lytic endotransglycosylase activity
XAUT_RS01970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XAUT_RS01990	COG0287	Prephenate dehydrogenase
XAUT_RS01995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XAUT_RS02015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XAUT_RS02020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XAUT_RS02045	COG2226	methyltransferase
XAUT_RS02050	COG0482	sulfurtransferase activity
XAUT_RS02070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
XAUT_RS02085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XAUT_RS02090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XAUT_RS02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XAUT_RS02120	COG2372	response to copper ion
XAUT_RS02120	COG1276	copper resistance
XAUT_RS02155	COG3246	L-lysine catabolic process to acetate
XAUT_RS02160	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS02165	COG1129	ABC transporter
XAUT_RS02180	COG1802	Transcriptional regulator
XAUT_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS02195	COG1431	PFAM Stem cell self-renewal protein Piwi
XAUT_RS02235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XAUT_RS02245	COG0582	viral genome integration into host DNA
XAUT_RS02250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XAUT_RS02250	COG0519	Catalyzes the synthesis of GMP from XMP
XAUT_RS02300	COG1309	transcriptional regulator
XAUT_RS02310	COG1131	(ABC) transporter
XAUT_RS02315	COG0842	Transport permease protein
XAUT_RS02320	COG3278	Belongs to the heme-copper respiratory oxidase family
XAUT_RS02335	COG2010	Cytochrome c
XAUT_RS02350	COG2217	Heavy metal translocating P-type atpase
XAUT_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS02370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XAUT_RS02375	COG2967	ApaG domain
XAUT_RS02385	COG0717	Belongs to the dCTP deaminase family
XAUT_RS02395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XAUT_RS02410	COG0069	glutamate synthase activity
XAUT_RS02410	COG0070	glutamate synthase
XAUT_RS02410	COG0067	glutamate synthase
XAUT_RS02415	COG1238	metal cluster binding
XAUT_RS02420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XAUT_RS02425	COG1414	Transcriptional regulator
XAUT_RS02445	COG1802	Transcriptional regulator
XAUT_RS02455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XAUT_RS02460	COG4191	Histidine kinase
XAUT_RS02470	COG0045	succinate-CoA ligase (ADP-forming) activity
XAUT_RS02475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XAUT_RS02480	COG0179	Fumarylacetoacetate (FAA) hydrolase
XAUT_RS02490	COG0574	Belongs to the PEP-utilizing enzyme family
XAUT_RS02490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XAUT_RS02505	COG0395	ABC-type sugar transport system, permease component
XAUT_RS02510	COG3547	Transposase (IS116 IS110 IS902 family)
XAUT_RS02530	COG3842	ATPase activity
XAUT_RS02535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XAUT_RS02550	COG1872	DUF167
XAUT_RS02560	COG0825	malonyl-CoA metabolic process
XAUT_RS02565	COG3034	peptidoglycan biosynthetic process
XAUT_RS02575	COG0653	protein targeting
XAUT_RS02580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS02595	COG2308	Evidence 4 Homologs of previously reported genes of
XAUT_RS02595	COG2307	Protein conserved in bacteria
XAUT_RS02600	COG1305	Transglutaminase-like
XAUT_RS02605	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS02645	COG4974	Belongs to the 'phage' integrase family
XAUT_RS02665	COG4974	Belongs to the 'phage' integrase family
XAUT_RS02680	COG4227	nucleotidyltransferase activity
XAUT_RS02710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAUT_RS02780	COG1475	DNA binding
XAUT_RS02790	COG1396	sequence-specific DNA binding
XAUT_RS02805	COG3621	Patatin-like phospholipase
XAUT_RS02840	COG2963	transposase activity
XAUT_RS02845	COG2801	Transposase and inactivated derivatives
XAUT_RS02880	COG1475	DNA binding
XAUT_RS02905	COG5489	Protein of unknown function (DUF736)
XAUT_RS02910	COG1396	sequence-specific DNA binding
XAUT_RS02935	COG1192	Involved in chromosome partitioning
XAUT_RS02980	COG3177	Filamentation induced by cAMP protein fic
XAUT_RS03000	COG4962	Type ii secretion system protein e
XAUT_RS03015	COG3451	type IV secretory pathway VirB4
XAUT_RS03090	COG0347	Belongs to the P(II) protein family
XAUT_RS03120	COG4974	Belongs to the 'phage' integrase family
XAUT_RS03130	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS03135	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS03135	COG1024	Enoyl-CoA hydratase
XAUT_RS03140	COG0183	Belongs to the thiolase family
XAUT_RS03145	COG1309	transcriptional regulator
XAUT_RS03155	COG0242	peptide deformylase activity
XAUT_RS03165	COG0583	DNA-binding transcription factor activity
XAUT_RS03170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XAUT_RS03175	COG3852	Histidine kinase
XAUT_RS03200	COG0528	UMP kinase activity
XAUT_RS03205	COG0528	UMP kinase activity
XAUT_RS03215	COG1982	Orn Lys Arg decarboxylase major
XAUT_RS03225	COG0411	ABC transporter
XAUT_RS03265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XAUT_RS03280	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XAUT_RS03315	COG1921	L-seryl-tRNASec selenium transferase activity
XAUT_RS03325	COG2864	formate dehydrogenase
XAUT_RS03330	COG0437	4 iron, 4 sulfur cluster binding
XAUT_RS03335	COG3383	formate dehydrogenase (NAD+) activity
XAUT_RS03335	COG0243	molybdopterin cofactor binding
XAUT_RS03340	COG3383	formate dehydrogenase (NAD+) activity
XAUT_RS03340	COG0243	molybdopterin cofactor binding
XAUT_RS03355	COG0709	Synthesizes selenophosphate from selenide and ATP
XAUT_RS03370	COG1063	alcohol dehydrogenase
XAUT_RS03385	COG0210	DNA helicase
XAUT_RS03390	COG3593	DNA synthesis involved in DNA repair
XAUT_RS03430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XAUT_RS03445	COG2801	Transposase and inactivated derivatives
XAUT_RS03450	COG2963	transposase activity
XAUT_RS03465	COG0583	DNA-binding transcription factor activity
XAUT_RS03495	COG3846	protein secretion by the type IV secretion system
XAUT_RS03510	COG3451	type IV secretory pathway VirB4
XAUT_RS03525	COG4962	Type ii secretion system protein e
XAUT_RS03550	COG0741	lytic transglycosylase activity
XAUT_RS03575	COG1192	Involved in chromosome partitioning
XAUT_RS03600	COG5489	Protein of unknown function (DUF736)
XAUT_RS03675	COG2003	Belongs to the UPF0758 family
XAUT_RS03695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS03710	COG2948	multi-organism process
XAUT_RS03725	COG3846	protein secretion by the type IV secretion system
XAUT_RS03740	COG3451	type IV secretory pathway VirB4
XAUT_RS03755	COG4962	Type ii secretion system protein e
XAUT_RS03780	COG0741	lytic transglycosylase activity
XAUT_RS03805	COG1192	Involved in chromosome partitioning
XAUT_RS03820	COG1476	TRANSCRIPTIONal
XAUT_RS03825	COG5489	Protein of unknown function (DUF736)
XAUT_RS03915	COG1074	ATP-dependent DNA helicase activity
XAUT_RS03965	COG0582	viral genome integration into host DNA
XAUT_RS03970	COG2003	Belongs to the UPF0758 family
XAUT_RS03985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAUT_RS03990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAUT_RS04015	COG4227	nucleotidyltransferase activity
XAUT_RS04035	COG4974	Belongs to the 'phage' integrase family
XAUT_RS04050	COG0587	DNA-directed DNA polymerase activity
XAUT_RS04125	COG2814	Major facilitator Superfamily
XAUT_RS04135	COG2814	Major facilitator Superfamily
XAUT_RS04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS04155	COG2610	gluconate transmembrane transporter activity
XAUT_RS04160	COG0786	glutamate:sodium symporter activity
XAUT_RS04180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XAUT_RS04190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XAUT_RS04195	COG0477	Major facilitator Superfamily
XAUT_RS04205	COG0604	alcohol dehydrogenase
XAUT_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS04205	COG3321	synthase
XAUT_RS04220	COG0254	rRNA binding
XAUT_RS04225	COG1132	(ABC) transporter
XAUT_RS04250	COG0714	Associated with various cellular activities
XAUT_RS04265	COG2304	oxidoreductase activity
XAUT_RS04280	COG0583	DNA-binding transcription factor activity
XAUT_RS04295	COG1176	ABC-type spermidine putrescine transport system, permease component I
XAUT_RS04305	COG3842	ATPase activity
XAUT_RS04325	COG4149	molybdate abc transporter
XAUT_RS04330	COG1177	transmembrane transport
XAUT_RS04340	COG0446	pyridine nucleotide-disulphide oxidoreductase
XAUT_RS04340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAUT_RS04350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAUT_RS04355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XAUT_RS04385	COG1393	Belongs to the ArsC family
XAUT_RS04390	COG0798	PFAM Bile acid sodium symporter
XAUT_RS04395	COG0431	NADPH-dependent FMN reductase
XAUT_RS04415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XAUT_RS04440	COG0174	glutamine synthetase
XAUT_RS04445	COG0519	Catalyzes the synthesis of GMP from XMP
XAUT_RS04445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XAUT_RS04465	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS04480	COG3327	negative regulation of DNA-templated transcription, initiation
XAUT_RS04485	COG3396	Phenylacetate-CoA oxygenase
XAUT_RS04490	COG3460	Phenylacetate-CoA oxygenase
XAUT_RS04495	COG3396	Phenylacetate-CoA oxygenase
XAUT_RS04500	COG2151	metal-sulfur cluster biosynthetic enzyme
XAUT_RS04505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XAUT_RS04515	COG2050	protein possibly involved in aromatic compounds catabolism
XAUT_RS04520	COG1024	Enoyl-CoA hydratase
XAUT_RS04530	COG0183	Belongs to the thiolase family
XAUT_RS04540	COG1012	belongs to the aldehyde dehydrogenase family
XAUT_RS04540	COG2030	dehydratase
XAUT_RS04585	COG1846	Transcriptional regulator
XAUT_RS04595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XAUT_RS04605	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS04610	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS04610	COG1024	Enoyl-CoA hydratase
XAUT_RS04615	COG0183	Belongs to the thiolase family
XAUT_RS04625	COG2181	nitrate reductase activity
XAUT_RS04625	COG0247	lactate metabolic process
XAUT_RS04650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAUT_RS04665	COG1414	Transcriptional regulator
XAUT_RS04670	COG0179	Fumarylacetoacetate (FAA) hydrolase
XAUT_RS04675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS04685	COG0477	Major facilitator Superfamily
XAUT_RS04690	COG1414	Transcriptional regulator
XAUT_RS04695	COG1355	regulation of microtubule-based process
XAUT_RS04705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XAUT_RS04715	COG3971	2-oxopent-4-enoate hydratase activity
XAUT_RS04720	COG4569	acetaldehyde dehydrogenase (acetylating) activity
XAUT_RS04725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XAUT_RS04730	COG2814	Major facilitator Superfamily
XAUT_RS04740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XAUT_RS04740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XAUT_RS04745	COG1032	radical SAM domain protein
XAUT_RS04775	COG0583	DNA-binding transcription factor activity
XAUT_RS04780	COG1942	4-Oxalocrotonate Tautomerase
XAUT_RS04790	COG0583	DNA-binding transcription factor activity
XAUT_RS04810	COG0596	Alpha beta hydrolase
XAUT_RS04815	COG2267	carboxylic ester hydrolase activity
XAUT_RS04825	COG1595	DNA-templated transcription, initiation
XAUT_RS04840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XAUT_RS04845	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
XAUT_RS04870	COG0535	radical SAM domain protein
XAUT_RS04890	COG0583	DNA-binding transcription factor activity
XAUT_RS04895	COG0583	DNA-binding transcription factor activity
XAUT_RS04900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XAUT_RS04935	COG0625	glutathione transferase activity
XAUT_RS04940	COG0625	glutathione transferase activity
XAUT_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS04965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XAUT_RS04985	COG0667	Aldo Keto reductase
XAUT_RS04995	COG2205	protein histidine kinase activity
XAUT_RS05005	COG0515	serine threonine protein kinase
XAUT_RS05005	COG2815	serine threonine protein kinase
XAUT_RS05010	COG0631	protein serine/threonine phosphatase activity
XAUT_RS05040	COG1819	glycosyl
XAUT_RS05050	COG2986	histidine ammonia-lyase
XAUT_RS05060	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS05080	COG3321	synthase
XAUT_RS05080	COG0604	alcohol dehydrogenase
XAUT_RS05105	COG0583	DNA-binding transcription factor activity
XAUT_RS05115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XAUT_RS05120	COG0129	dihydroxy-acid dehydratase activity
XAUT_RS05145	COG0655	NAD(P)H dehydrogenase (quinone) activity
XAUT_RS05150	COG1741	Belongs to the pirin family
XAUT_RS05155	COG3395	kinase activity
XAUT_RS05160	COG3622	Belongs to the hyi family
XAUT_RS05165	COG2084	Dehydrogenase
XAUT_RS05170	COG2271	Major facilitator Superfamily
XAUT_RS05175	COG1609	Transcriptional regulator
XAUT_RS05180	COG0235	Class ii aldolase
XAUT_RS05190	COG2204	response regulator
XAUT_RS05195	COG2205	protein histidine kinase activity
XAUT_RS05220	COG2076	Multidrug Resistance protein
XAUT_RS05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XAUT_RS05240	COG2801	Transposase and inactivated derivatives
XAUT_RS05245	COG0583	DNA-binding transcription factor activity
XAUT_RS05260	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS05290	COG0154	amidase activity
XAUT_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS05305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS05320	COG0667	Aldo Keto reductase
XAUT_RS05325	COG0583	DNA-binding transcription factor activity
XAUT_RS05340	COG2801	Transposase and inactivated derivatives
XAUT_RS05350	COG1404	Belongs to the peptidase S8 family
XAUT_RS05370	COG1388	LysM domain
XAUT_RS05370	COG1376	ErfK ybiS ycfS ynhG family protein
XAUT_RS05380	COG4232	protein-disulfide reductase activity
XAUT_RS05400	COG0243	molybdopterin cofactor binding
XAUT_RS05405	COG2146	nitrite reductase [NAD(P)H] activity
XAUT_RS05410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XAUT_RS05420	COG1116	anion transmembrane transporter activity
XAUT_RS05420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS05425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS05430	COG1116	anion transmembrane transporter activity
XAUT_RS05430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS05435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS05440	COG3707	response regulator
XAUT_RS05450	COG1404	Belongs to the peptidase S8 family
XAUT_RS05460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAUT_RS05480	COG1715	Restriction endonuclease
XAUT_RS05490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XAUT_RS05500	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XAUT_RS05540	COG0640	Transcriptional regulator
XAUT_RS05545	COG2264	protein methyltransferase activity
XAUT_RS05565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XAUT_RS05570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XAUT_RS05595	COG2204	response regulator
XAUT_RS05605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XAUT_RS05610	COG2267	carboxylic ester hydrolase activity
XAUT_RS05615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XAUT_RS05625	COG4829	muconolactone delta-isomerase
XAUT_RS05630	COG0183	Belongs to the thiolase family
XAUT_RS05635	COG1414	Transcriptional regulator
XAUT_RS05645	COG0667	Aldo Keto reductase
XAUT_RS05650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS05655	COG1464	Belongs to the NlpA lipoprotein family
XAUT_RS05705	COG2271	Major facilitator Superfamily
XAUT_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS05725	COG0174	glutamine synthetase
XAUT_RS05730	COG4106	trans-aconitate 2-methyltransferase activity
XAUT_RS05735	COG1464	Belongs to the NlpA lipoprotein family
XAUT_RS05740	COG2011	ABC-type metal ion transport system permease component
XAUT_RS05745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XAUT_RS05750	COG1309	transcriptional regulator
XAUT_RS05770	COG1309	transcriptional regulator
XAUT_RS05785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XAUT_RS05795	COG0123	including yeast histone deacetylase and acetoin utilization protein
XAUT_RS05800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XAUT_RS05805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XAUT_RS05810	COG0181	hydroxymethylbilane synthase activity
XAUT_RS05830	COG0481	GTPase activity
XAUT_RS05835	COG2066	Belongs to the glutaminase family
XAUT_RS05835	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XAUT_RS05850	COG0459	protein refolding
XAUT_RS05855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XAUT_RS05860	COG0583	DNA-binding transcription factor activity
XAUT_RS05870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XAUT_RS05880	COG1194	a g-specific adenine glycosylase
XAUT_RS05885	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XAUT_RS05900	COG2084	Dehydrogenase
XAUT_RS05905	COG1609	Transcriptional regulator
XAUT_RS05915	COG1285	pathogenesis
XAUT_RS05920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XAUT_RS05930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XAUT_RS05935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XAUT_RS05945	COG0066	3-isopropylmalate dehydratase activity
XAUT_RS05950	COG3038	cytochrome b561
XAUT_RS05960	COG1201	RNA secondary structure unwinding
XAUT_RS05975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XAUT_RS05980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XAUT_RS05995	COG0604	alcohol dehydrogenase
XAUT_RS06005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XAUT_RS06005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XAUT_RS06015	COG2514	catechol 2,3-dioxygenase activity
XAUT_RS06020	COG0697	spore germination
XAUT_RS06030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XAUT_RS06040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XAUT_RS06045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XAUT_RS06050	COG1121	(ABC) transporter
XAUT_RS06055	COG0803	Belongs to the bacterial solute-binding protein 9 family
XAUT_RS06060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XAUT_RS06060	COG4651	solute:proton antiporter activity
XAUT_RS06065	COG1116	anion transmembrane transporter activity
XAUT_RS06070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS06075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS06080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XAUT_RS06085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS06095	COG1376	ErfK ybiS ycfS ynhG family protein
XAUT_RS06110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XAUT_RS06115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XAUT_RS06135	COG3665	Urea carboxylase-associated protein
XAUT_RS06140	COG3665	Urea carboxylase-associated protein
XAUT_RS06145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XAUT_RS06180	COG5328	Belongs to the UPF0262 family
XAUT_RS06195	COG3265	gluconokinase activity
XAUT_RS06200	COG1609	Transcriptional regulator
XAUT_RS06210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XAUT_RS06215	COG0358	DNA primase activity
XAUT_RS06225	COG1115	amino acid carrier protein
XAUT_RS06235	COG0505	Belongs to the CarA family
XAUT_RS06240	COG1802	Transcriptional regulator
XAUT_RS06250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XAUT_RS06270	COG0166	Belongs to the GPI family
XAUT_RS06275	COG0363	glucosamine-6-phosphate deaminase activity
XAUT_RS06280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XAUT_RS06285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XAUT_RS06295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XAUT_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS06320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XAUT_RS06330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XAUT_RS06335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XAUT_RS06340	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS06345	COG2321	neutral zinc metallopeptidase
XAUT_RS06350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XAUT_RS06355	COG1294	oxidase, subunit
XAUT_RS06360	COG1271	oxidase subunit
XAUT_RS06370	COG1116	anion transmembrane transporter activity
XAUT_RS06380	COG2814	Major facilitator Superfamily
XAUT_RS06390	COG1574	metal-dependent hydrolase with the TIM-barrel fold
XAUT_RS06405	COG1335	isochorismatase
XAUT_RS06415	COG1917	Cupin 2, conserved barrel domain protein
XAUT_RS06415	COG2207	Transcriptional regulator
XAUT_RS06430	COG2226	methyltransferase
XAUT_RS06440	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS06450	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS06465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAUT_RS06465	COG2080	2 iron, 2 sulfur cluster binding
XAUT_RS06475	COG4191	Histidine kinase
XAUT_RS06485	COG2223	nitrite transmembrane transporter activity
XAUT_RS06490	COG4221	oxidoreductase activity
XAUT_RS06560	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XAUT_RS06565	COG3454	Phosphonate metabolism
XAUT_RS06570	COG4778	phosphonate C-P lyase system protein PhnL
XAUT_RS06575	COG4107	phosphonate C-P lyase system protein PhnK
XAUT_RS06580	COG3627	carbon phosphorus lyase activity
XAUT_RS06585	COG3626	phosphonate metabolism
XAUT_RS06590	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
XAUT_RS06595	COG3624	Phosphonate C-P lyase system protein PhnG
XAUT_RS06600	COG2188	Transcriptional regulator
XAUT_RS06625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XAUT_RS06640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XAUT_RS06645	COG0384	phenazine biosynthesis protein PhzF
XAUT_RS06650	COG1902	pentaerythritol trinitrate reductase activity
XAUT_RS06660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XAUT_RS06690	COG0183	Belongs to the thiolase family
XAUT_RS06695	COG0523	cobalamin synthesis protein
XAUT_RS06700	COG3284	Transcriptional regulator
XAUT_RS06705	COG0145	ligase activity
XAUT_RS06710	COG4647	ligase activity
XAUT_RS06735	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
XAUT_RS06740	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS06750	COG2301	Belongs to the HpcH HpaI aldolase family
XAUT_RS06760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XAUT_RS06775	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS06795	COG1012	belongs to the aldehyde dehydrogenase family
XAUT_RS06835	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
XAUT_RS06875	COG0142	geranyltranstransferase activity
XAUT_RS06885	COG2890	protein-(glutamine-N5) methyltransferase activity
XAUT_RS06905	COG1742	UPF0060 membrane protein
XAUT_RS06910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XAUT_RS06920	COG2759	Belongs to the formate--tetrahydrofolate ligase family
XAUT_RS06925	COG0183	Belongs to the thiolase family
XAUT_RS06940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XAUT_RS06960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XAUT_RS06965	COG4208	sulfate ABC transporter
XAUT_RS06980	COG0175	sulfate reduction
XAUT_RS06990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XAUT_RS07000	COG0175	sulfate reduction
XAUT_RS07010	COG1024	Enoyl-CoA hydratase
XAUT_RS07025	COG2166	iron-sulfur cluster assembly
XAUT_RS07035	COG2205	protein histidine kinase activity
XAUT_RS07070	COG0151	Belongs to the GarS family
XAUT_RS07075	COG1570	exodeoxyribonuclease VII activity
XAUT_RS07085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XAUT_RS07095	COG2818	Glycosylase
XAUT_RS07120	COG0277	FAD linked oxidase domain protein
XAUT_RS07130	COG2264	protein methyltransferase activity
XAUT_RS07135	COG3706	GGDEF domain
XAUT_RS07140	COG0210	DNA helicase
XAUT_RS07165	COG0628	permease
XAUT_RS07210	COG3135	benzoate transporter
XAUT_RS07220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XAUT_RS07240	COG0495	leucyl-tRNA aminoacylation
XAUT_RS07255	COG2223	nitrite transmembrane transporter activity
XAUT_RS07265	COG0432	Pfam Uncharacterised protein family UPF0047
XAUT_RS07270	COG0657	acetylesterase activity
XAUT_RS07315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XAUT_RS07320	COG0228	four-way junction DNA binding
XAUT_RS07340	COG0534	Mate efflux family protein
XAUT_RS07355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XAUT_RS07355	COG1793	dna ligase
XAUT_RS07360	COG1793	dna ligase
XAUT_RS07360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XAUT_RS07370	COG2814	Major facilitator Superfamily
XAUT_RS07380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
XAUT_RS07400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAUT_RS07410	COG1663	tetraacyldisaccharide 4'-kinase activity
XAUT_RS07415	COG1519	Transferase
XAUT_RS07430	COG1218	3'(2'),5'-bisphosphate nucleotidase
XAUT_RS07435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XAUT_RS07445	COG0028	Belongs to the TPP enzyme family
XAUT_RS07455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XAUT_RS07485	COG1984	allophanate hydrolase subunit 2
XAUT_RS07495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XAUT_RS07505	COG1137	ATPase activity
XAUT_RS07510	COG1079	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS07515	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS07525	COG4336	lyase activity
XAUT_RS07545	COG0583	DNA-binding transcription factor activity
XAUT_RS07550	COG0625	glutathione transferase activity
XAUT_RS07555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS07580	COG0446	pyridine nucleotide-disulphide oxidoreductase
XAUT_RS07595	COG3258	Cytochrome c
XAUT_RS07620	COG3258	Cytochrome c
XAUT_RS07625	COG2010	Cytochrome c
XAUT_RS07635	COG0785	Cytochrome C biogenesis protein
XAUT_RS07650	COG2391	methyltransferase activity
XAUT_RS07655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS07665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS07680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XAUT_RS07695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XAUT_RS07700	COG2084	Dehydrogenase
XAUT_RS07705	COG3958	Transketolase
XAUT_RS07710	COG3959	Transketolase, thiamine diphosphate binding domain
XAUT_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS07720	COG0583	DNA-binding transcription factor activity
XAUT_RS07740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XAUT_RS07760	COG2066	Belongs to the glutaminase family
XAUT_RS07760	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XAUT_RS07765	COG4191	Histidine kinase
XAUT_RS07770	COG4566	intracellular signal transduction
XAUT_RS07790	COG1278	Cold shock
XAUT_RS07800	COG3459	Glycosyltransferase 36 associated
XAUT_RS07825	COG0683	leucine binding
XAUT_RS07870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XAUT_RS07875	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAUT_RS07920	COG0651	ATP synthesis coupled electron transport
XAUT_RS07925	COG1007	ATP synthesis coupled electron transport
XAUT_RS07965	COG0443	Heat shock 70 kDa protein
XAUT_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS08000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS08005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS08015	COG0765	amino acid transport
XAUT_RS08020	COG0765	amino acid transport
XAUT_RS08025	COG2721	sulfolactate sulfo-lyase activity
XAUT_RS08045	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XAUT_RS08060	COG2801	Transposase and inactivated derivatives
XAUT_RS08080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XAUT_RS08085	COG0277	FAD linked oxidase domain protein
XAUT_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS08095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XAUT_RS08120	COG3321	synthase
XAUT_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS08120	COG0604	alcohol dehydrogenase
XAUT_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS08135	COG2186	Transcriptional regulator
XAUT_RS08150	COG2202	Pas domain
XAUT_RS08150	COG2205	protein histidine kinase activity
XAUT_RS08165	COG1595	DNA-templated transcription, initiation
XAUT_RS08180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XAUT_RS08185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XAUT_RS08195	COG4974	Belongs to the 'phage' integrase family
XAUT_RS08215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XAUT_RS08220	COG1376	ErfK ybiS ycfS ynhG family protein
XAUT_RS08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS08235	COG1324	tolerance protein
XAUT_RS08240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XAUT_RS08255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XAUT_RS08260	COG1752	Esterase of the alpha-beta hydrolase superfamily
XAUT_RS08265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XAUT_RS08270	COG0302	gtp cyclohydrolase
XAUT_RS08285	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XAUT_RS08290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XAUT_RS08300	COG4235	cytochrome complex assembly
XAUT_RS08305	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XAUT_RS08310	COG1138	Cytochrome C-type biogenesis protein
XAUT_RS08315	COG3088	subunit of a heme lyase
XAUT_RS08320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XAUT_RS08325	COG0560	Phosphoserine phosphatase
XAUT_RS08330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XAUT_RS08340	COG0330	HflC and HflK could
XAUT_RS08345	COG0330	HflC and HflK could
XAUT_RS08360	COG0114	fumarate hydratase activity
XAUT_RS08370	COG1704	LemA family
XAUT_RS08375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XAUT_RS08390	COG0039	L-malate dehydrogenase activity
XAUT_RS08395	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XAUT_RS08400	COG0049	tRNA binding
XAUT_RS08405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XAUT_RS08410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XAUT_RS08415	COG0051	transcription antitermination factor activity, RNA binding
XAUT_RS08420	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XAUT_RS08425	COG0088	Forms part of the polypeptide exit tunnel
XAUT_RS08430	COG0089	rRNA binding
XAUT_RS08435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XAUT_RS08440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XAUT_RS08445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XAUT_RS08450	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XAUT_RS08455	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XAUT_RS08460	COG0255	Belongs to the universal ribosomal protein uL29 family
XAUT_RS08465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XAUT_RS08470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XAUT_RS08475	COG0268	Binds directly to 16S ribosomal RNA
XAUT_RS08485	COG0135	phosphoribosylanthranilate isomerase activity
XAUT_RS08490	COG0133	tryptophan synthase activity
XAUT_RS08500	COG0159	tryptophan synthase activity
XAUT_RS08505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XAUT_RS08515	COG0129	dihydroxy-acid dehydratase activity
XAUT_RS08520	COG2186	Transcriptional regulator
XAUT_RS08535	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS08555	COG1942	4-Oxalocrotonate Tautomerase
XAUT_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS08590	COG3959	Transketolase, thiamine diphosphate binding domain
XAUT_RS08595	COG3958	Transketolase
XAUT_RS08600	COG0371	Dehydrogenase
XAUT_RS08640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XAUT_RS08685	COG0427	acetyl-CoA hydrolase
XAUT_RS08695	COG0138	bifunctional purine biosynthesis protein purh
XAUT_RS08705	COG1215	transferase activity, transferring glycosyl groups
XAUT_RS08715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XAUT_RS08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAUT_RS08725	COG0165	Argininosuccinate lyase
XAUT_RS08735	COG0019	diaminopimelate decarboxylase activity
XAUT_RS08740	COG3300	MHYT domain
XAUT_RS08740	COG5001	Diguanylate cyclase
XAUT_RS08745	COG0045	succinate-CoA ligase (ADP-forming) activity
XAUT_RS08745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XAUT_RS08745	COG1042	CoA-binding domain protein
XAUT_RS08750	COG4566	intracellular signal transduction
XAUT_RS08755	COG4566	intracellular signal transduction
XAUT_RS08760	COG4191	Histidine kinase
XAUT_RS08765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAUT_RS08770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XAUT_RS08805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XAUT_RS08810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAUT_RS08825	COG4181	ATPase activity
XAUT_RS08845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XAUT_RS08850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XAUT_RS08870	COG1556	Lactate utilization protein
XAUT_RS08875	COG1139	Iron-sulfur cluster binding protein
XAUT_RS08880	COG0247	lactate metabolic process
XAUT_RS08890	COG0745	RESPONSE REGULATOR receiver
XAUT_RS08905	COG1301	dicarboxylic acid transport
XAUT_RS08910	COG4191	Histidine kinase
XAUT_RS08915	COG2204	response regulator
XAUT_RS08970	COG0702	epimerase
XAUT_RS09005	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
XAUT_RS09010	COG1229	Formylmethanofuran dehydrogenase subunit A
XAUT_RS09030	COG0535	radical SAM domain protein
XAUT_RS09035	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XAUT_RS09040	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XAUT_RS09045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XAUT_RS09050	COG0745	RESPONSE REGULATOR receiver
XAUT_RS09055	COG5002	protein histidine kinase activity
XAUT_RS09060	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XAUT_RS09080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XAUT_RS09085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XAUT_RS09090	COG1702	phosphate starvation-inducible protein PhoH
XAUT_RS09095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XAUT_RS09100	COG1253	flavin adenine dinucleotide binding
XAUT_RS09105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XAUT_RS09110	COG1396	sequence-specific DNA binding
XAUT_RS09115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XAUT_RS09120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XAUT_RS09150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XAUT_RS09155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XAUT_RS09160	COG1981	membrane
XAUT_RS09165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XAUT_RS09170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XAUT_RS09175	COG0424	maF-like protein
XAUT_RS09180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XAUT_RS09185	COG0237	dephospho-CoA kinase activity
XAUT_RS09190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XAUT_RS09195	COG1331	Highly conserved protein containing a thioredoxin domain
XAUT_RS09200	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XAUT_RS09205	COG0445	tRNA wobble uridine modification
XAUT_RS09210	COG0357	Ribosomal RNA small subunit methyltransferase G
XAUT_RS09225	COG4957	zinc ion binding
XAUT_RS09230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XAUT_RS09240	COG1674	ftsk spoiiie
XAUT_RS09245	COG0436	Aminotransferase
XAUT_RS09250	COG0196	riboflavin kinase activity
XAUT_RS09260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XAUT_RS09270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XAUT_RS09275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XAUT_RS09280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XAUT_RS09295	COG0275	rRNA processing
XAUT_RS09300	COG2001	Belongs to the MraZ family
XAUT_RS09315	COG1024	Enoyl-CoA hydratase
XAUT_RS09320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XAUT_RS09330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAUT_RS09340	COG1022	Amp-dependent synthetase and ligase
XAUT_RS09370	COG0352	thiamine-phosphate diphosphorylase activity
XAUT_RS09375	COG0247	lactate metabolic process
XAUT_RS09380	COG0277	FAD linked oxidase domain protein
XAUT_RS09385	COG0277	FAD linked oxidase domain protein
XAUT_RS09390	COG0583	DNA-binding transcription factor activity
XAUT_RS09405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XAUT_RS09435	COG0330	HflC and HflK could
XAUT_RS09440	COG1585	Membrane protein implicated in regulation of membrane protease activity
XAUT_RS09450	COG0564	pseudouridine synthase activity
XAUT_RS09455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XAUT_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS09480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XAUT_RS09495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAUT_RS09500	COG1132	(ABC) transporter
XAUT_RS09515	COG3023	N-Acetylmuramoyl-L-alanine amidase
XAUT_RS09545	COG0542	response to heat
XAUT_RS09560	COG0739	heme binding
XAUT_RS09590	COG0697	spore germination
XAUT_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS09605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAUT_RS09610	COG2813	Specifically methylates the guanine in position
XAUT_RS09610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAUT_RS09615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XAUT_RS09635	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XAUT_RS09650	COG1850	ribulose-bisphosphate carboxylase activity
XAUT_RS09665	COG0706	membrane insertase activity
XAUT_RS09670	COG0594	ribonuclease P activity
XAUT_RS09675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XAUT_RS09680	COG1132	(ABC) transporter
XAUT_RS09685	COG1686	Belongs to the peptidase S11 family
XAUT_RS09690	COG0523	cobalamin synthesis protein
XAUT_RS09700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XAUT_RS09700	COG0493	'glutamate synthase
XAUT_RS09705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XAUT_RS09710	COG0072	phenylalanine-tRNA ligase activity
XAUT_RS09710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XAUT_RS09715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XAUT_RS09720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XAUT_RS09725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XAUT_RS09750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XAUT_RS09760	COG0174	glutamine synthetase
XAUT_RS09765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAUT_RS09775	COG1253	flavin adenine dinucleotide binding
XAUT_RS09780	COG1597	lipid kinase activity
XAUT_RS09785	COG1309	transcriptional regulator
XAUT_RS09820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XAUT_RS09830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XAUT_RS09845	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XAUT_RS09905	COG3047	cAMP biosynthetic process
XAUT_RS09915	COG2030	dehydratase
XAUT_RS09945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XAUT_RS09950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XAUT_RS09960	COG0356	it plays a direct role in the translocation of protons across the membrane
XAUT_RS09970	COG1196	nuclear chromosome segregation
XAUT_RS09980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XAUT_RS09990	COG0564	pseudouridine synthase activity
XAUT_RS09995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XAUT_RS10005	COG1994	Peptidase M50
XAUT_RS10015	COG2814	Major facilitator Superfamily
XAUT_RS10040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS10045	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS10055	COG0129	dihydroxy-acid dehydratase activity
XAUT_RS10080	COG1122	ATPase activity
XAUT_RS10085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
XAUT_RS10090	COG1268	BioY protein
XAUT_RS10095	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS10130	COG0137	argininosuccinate synthase activity
XAUT_RS10145	COG2226	methyltransferase
XAUT_RS10150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XAUT_RS10160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAUT_RS10185	COG0784	Response regulator, receiver
XAUT_RS10210	COG0505	Belongs to the CarA family
XAUT_RS10220	COG0069	glutamate synthase activity
XAUT_RS10235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAUT_RS10240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XAUT_RS10245	COG3038	cytochrome b561
XAUT_RS10250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAUT_RS10250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAUT_RS10270	COG3958	Transketolase
XAUT_RS10275	COG3959	Transketolase, thiamine diphosphate binding domain
XAUT_RS10280	COG0670	Belongs to the BI1 family
XAUT_RS10295	COG0583	DNA-binding transcription factor activity
XAUT_RS10300	COG0837	glucose binding
XAUT_RS10310	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XAUT_RS10340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XAUT_RS10345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XAUT_RS10355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XAUT_RS10360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XAUT_RS10365	COG0799	negative regulation of ribosome biogenesis
XAUT_RS10370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XAUT_RS10375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XAUT_RS10395	COG3750	Belongs to the UPF0335 family
XAUT_RS10400	COG3108	Peptidase M15
XAUT_RS10405	COG2989	Protein conserved in bacteria
XAUT_RS10410	COG0745	RESPONSE REGULATOR receiver
XAUT_RS10425	COG0793	Belongs to the peptidase S41A family
XAUT_RS10430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS10435	COG0765	amino acid transport
XAUT_RS10440	COG0765	amino acid transport
XAUT_RS10450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XAUT_RS10455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XAUT_RS10460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XAUT_RS10465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XAUT_RS10475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XAUT_RS10480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAUT_RS10485	COG4521	taurine ABC transporter
XAUT_RS10495	COG1116	anion transmembrane transporter activity
XAUT_RS10500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XAUT_RS10510	COG2855	membrane
XAUT_RS10520	COG0488	(ABC) transporter
XAUT_RS10530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XAUT_RS10535	COG1511	domain protein
XAUT_RS10535	COG3264	Mechanosensitive ion channel
XAUT_RS10545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAUT_RS10600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XAUT_RS10605	COG1459	type II secretion system
XAUT_RS10690	COG0156	8-amino-7-oxononanoate synthase activity
XAUT_RS10700	COG1607	acyl-coa hydrolase
XAUT_RS10705	COG1643	Atp-dependent helicase
XAUT_RS10720	COG4689	acetoacetate decarboxylase
XAUT_RS10775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XAUT_RS10780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XAUT_RS10785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XAUT_RS10790	COG0494	nUDIX hydrolase
XAUT_RS10805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XAUT_RS10810	COG3842	ATPase activity
XAUT_RS10815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XAUT_RS10830	COG1609	Transcriptional regulator
XAUT_RS10850	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS10855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XAUT_RS10860	COG2086	electron transfer activity
XAUT_RS10880	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XAUT_RS10895	COG2183	response to ionizing radiation
XAUT_RS10900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XAUT_RS10905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XAUT_RS10965	COG0375	protein maturation
XAUT_RS10975	COG2204	response regulator
XAUT_RS11005	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS11015	COG4691	Plasmid stability protein
XAUT_RS11030	COG3706	GGDEF domain
XAUT_RS11035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XAUT_RS11040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XAUT_RS11045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XAUT_RS11055	COG0509	glycine decarboxylation via glycine cleavage system
XAUT_RS11060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAUT_RS11070	COG0612	Peptidase, M16
XAUT_RS11075	COG0612	Peptidase, M16
XAUT_RS11085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XAUT_RS11090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XAUT_RS11095	COG0004	ammonium transporteR
XAUT_RS11100	COG0347	Belongs to the P(II) protein family
XAUT_RS11105	COG1946	Acyl-CoA thioesterase
XAUT_RS11110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS11115	COG2835	tetraacyldisaccharide 4'-kinase activity
XAUT_RS11120	COG0697	spore germination
XAUT_RS11125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XAUT_RS11140	COG4208	sulfate ABC transporter
XAUT_RS11150	COG0776	regulation of translation
XAUT_RS11155	COG0616	signal peptide processing
XAUT_RS11170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAUT_RS11170	COG2022	thiamine diphosphate biosynthetic process
XAUT_RS11180	COG2022	thiamine diphosphate biosynthetic process
XAUT_RS11185	COG0352	thiamine-phosphate diphosphorylase activity
XAUT_RS11190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS11200	COG0539	negative regulation of cytoplasmic translation
XAUT_RS11225	COG0582	viral genome integration into host DNA
XAUT_RS11250	COG4957	zinc ion binding
XAUT_RS11285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAUT_RS11325	COG3436	PFAM IS66 Orf2 family protein
XAUT_RS11330	COG4372	Transposase
XAUT_RS11375	COG0642	Histidine kinase
XAUT_RS11395	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAUT_RS11410	COG2132	Multicopper oxidase
XAUT_RS11430	COG1053	succinate dehydrogenase
XAUT_RS11460	COG0848	biopolymer transport protein
XAUT_RS11465	COG0811	peptide transport
XAUT_RS11490	COG3547	Transposase (IS116 IS110 IS902 family)
XAUT_RS11500	COG1072	(Pantothenic acid kinase))
XAUT_RS11505	COG0140	phosphoribosyl-ATP diphosphatase activity
XAUT_RS11510	COG0107	imidazoleglycerol-phosphate synthase activity
XAUT_RS11515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XAUT_RS11520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XAUT_RS11530	COG0131	Imidazoleglycerol-phosphate dehydratase
XAUT_RS11540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XAUT_RS11545	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XAUT_RS11550	COG2204	response regulator
XAUT_RS11560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XAUT_RS11570	COG0006	proline dipeptidase activity
XAUT_RS11595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAUT_RS11615	COG2814	Major facilitator Superfamily
XAUT_RS11625	COG0366	Alpha amylase catalytic
XAUT_RS11670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XAUT_RS11675	COG0753	catalase activity
XAUT_RS11685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XAUT_RS11690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XAUT_RS11695	COG0243	molybdopterin cofactor binding
XAUT_RS11700	COG0861	Integral membrane protein TerC family
XAUT_RS11705	COG0861	Integral membrane protein TerC family
XAUT_RS11710	COG0105	UTP biosynthetic process
XAUT_RS11720	COG0667	Aldo Keto reductase
XAUT_RS11725	COG4150	thiosulfate binding
XAUT_RS11730	COG3411	Ferredoxin
XAUT_RS11735	COG2204	response regulator
XAUT_RS11740	COG0784	Response regulator, receiver
XAUT_RS11745	COG2205	protein histidine kinase activity
XAUT_RS11750	COG0174	glutamine synthetase
XAUT_RS11765	COG0673	inositol 2-dehydrogenase activity
XAUT_RS11770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XAUT_RS11775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS11780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS11785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS11790	COG0322	excinuclease ABC activity
XAUT_RS11795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XAUT_RS11805	COG0314	molybdopterin synthase activity
XAUT_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS11830	COG0463	Glycosyl transferase, family 2
XAUT_RS11835	COG0589	response to stress
XAUT_RS11845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XAUT_RS11850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XAUT_RS11855	COG0328	RNA-DNA hybrid ribonuclease activity
XAUT_RS11865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS11880	COG3620	sequence-specific DNA binding
XAUT_RS11880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
XAUT_RS11880	COG0617	tRNA 3'-terminal CCA addition
XAUT_RS11885	COG0450	alkyl hydroperoxide reductase
XAUT_RS11895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XAUT_RS11905	COG3960	tartronate-semialdehyde synthase activity
XAUT_RS11910	COG3622	Belongs to the hyi family
XAUT_RS11915	COG2084	Dehydrogenase
XAUT_RS11920	COG0469	pyruvate kinase activity
XAUT_RS11925	COG2954	triphosphatase activity
XAUT_RS11945	COG1648	precorrin-2 dehydrogenase activity
XAUT_RS11945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XAUT_RS11950	COG0251	oxidation-reduction process
XAUT_RS11955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAUT_RS11955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAUT_RS11965	COG1999	signal sequence binding
XAUT_RS11970	COG2378	regulation of single-species biofilm formation
XAUT_RS11985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS11990	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XAUT_RS12030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS12050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS12060	COG0300	oxidoreductase activity
XAUT_RS12065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XAUT_RS12070	COG1286	toxin biosynthetic process
XAUT_RS12080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XAUT_RS12085	COG0305	Participates in initiation and elongation during chromosome replication
XAUT_RS12095	COG1597	lipid kinase activity
XAUT_RS12105	COG3706	GGDEF domain
XAUT_RS12110	COG2983	Belongs to the UPF0260 family
XAUT_RS12190	COG0488	(ABC) transporter
XAUT_RS12195	COG2176	DNA-directed DNA polymerase activity
XAUT_RS12195	COG5002	protein histidine kinase activity
XAUT_RS12200	COG0745	RESPONSE REGULATOR receiver
XAUT_RS12205	COG5002	protein histidine kinase activity
XAUT_RS12220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XAUT_RS12225	COG3162	membrane
XAUT_RS12230	COG2084	Dehydrogenase
XAUT_RS12245	COG1063	alcohol dehydrogenase
XAUT_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS12260	COG0765	amino acid transport
XAUT_RS12265	COG0765	amino acid transport
XAUT_RS12275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XAUT_RS12280	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
XAUT_RS12285	COG4251	negative regulation of phosphorylation
XAUT_RS12300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XAUT_RS12305	COG0583	DNA-binding transcription factor activity
XAUT_RS12310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS12315	COG1764	response to oxidative stress
XAUT_RS12330	COG0577	efflux transmembrane transporter activity
XAUT_RS12330	COG1136	(ABC) transporter
XAUT_RS12355	COG4988	ABC transporter
XAUT_RS12360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XAUT_RS12375	COG2824	Alkylphosphonate utilization operon protein PhnA
XAUT_RS12380	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS12400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS12405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS12410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS12420	COG2135	peptidase activity
XAUT_RS12430	COG0546	phosphoglycolate phosphatase activity
XAUT_RS12440	COG1376	ErfK ybiS ycfS ynhG family protein
XAUT_RS12440	COG1388	LysM domain
XAUT_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS12460	COG0259	pyridoxamine-phosphate oxidase activity
XAUT_RS12470	COG0484	heat shock protein binding
XAUT_RS12480	COG2030	dehydratase
XAUT_RS12515	COG0730	response to heat
XAUT_RS12535	COG3237	CsbD-like
XAUT_RS12540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XAUT_RS12545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XAUT_RS12550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XAUT_RS12565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XAUT_RS12570	COG0243	molybdopterin cofactor binding
XAUT_RS12575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XAUT_RS12580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XAUT_RS12585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XAUT_RS12595	COG1116	anion transmembrane transporter activity
XAUT_RS12600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS12605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS12610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS12615	COG3707	response regulator
XAUT_RS12635	COG0335	large ribosomal subunit rRNA binding
XAUT_RS12640	COG0336	Belongs to the RNA methyltransferase TrmD family
XAUT_RS12645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XAUT_RS12660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XAUT_RS12665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XAUT_RS12670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XAUT_RS12675	COG0277	FAD linked oxidase domain protein
XAUT_RS12735	COG1366	Belongs to the anti-sigma-factor antagonist family
XAUT_RS12740	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XAUT_RS12745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XAUT_RS12755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XAUT_RS12760	COG1420	regulation of RNA biosynthetic process
XAUT_RS12765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XAUT_RS12770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XAUT_RS12775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XAUT_RS12790	COG1671	Belongs to the UPF0178 family
XAUT_RS12800	COG3279	Response regulator of the LytR AlgR family
XAUT_RS12815	COG1160	GTP binding
XAUT_RS12830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XAUT_RS12840	COG1496	oxidoreductase activity
XAUT_RS12855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XAUT_RS12865	COG0671	phosphoesterase, PA-phosphatase related
XAUT_RS12875	COG1846	Transcriptional regulator
XAUT_RS12880	COG0745	RESPONSE REGULATOR receiver
XAUT_RS12890	COG0617	tRNA 3'-terminal CCA addition
XAUT_RS12910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XAUT_RS12915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XAUT_RS12920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XAUT_RS12940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XAUT_RS12945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XAUT_RS12950	COG3795	YCII-related domain
XAUT_RS12955	COG0583	DNA-binding transcription factor activity
XAUT_RS12960	COG2368	4-hydroxyphenylacetate
XAUT_RS12985	COG1177	transmembrane transport
XAUT_RS12990	COG3842	ATPase activity
XAUT_RS13000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XAUT_RS13010	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XAUT_RS13020	COG0494	nUDIX hydrolase
XAUT_RS13035	COG0473	3-isopropylmalate dehydrogenase activity
XAUT_RS13060	COG1678	Uncharacterized ACR, COG1678
XAUT_RS13070	COG0678	peroxiredoxin activity
XAUT_RS13085	COG0488	(ABC) transporter
XAUT_RS13115	COG0012	GTP binding
XAUT_RS13120	COG0193	aminoacyl-tRNA hydrolase activity
XAUT_RS13125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XAUT_RS13130	COG3258	Cytochrome c
XAUT_RS13155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XAUT_RS13170	COG1116	anion transmembrane transporter activity
XAUT_RS13170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS13175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS13180	COG1116	anion transmembrane transporter activity
XAUT_RS13185	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
XAUT_RS13195	COG2890	protein-(glutamine-N5) methyltransferase activity
XAUT_RS13200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XAUT_RS13205	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
XAUT_RS13210	COG0527	aspartate kinase activity
XAUT_RS13220	COG2816	NAD+ diphosphatase activity
XAUT_RS13235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XAUT_RS13240	COG3474	cytochrome
XAUT_RS13245	COG4166	transmembrane transport
XAUT_RS13250	COG4166	transmembrane transport
XAUT_RS13255	COG4174	ABC transporter (Permease)
XAUT_RS13260	COG4239	(ABC) transporter, permease
XAUT_RS13265	COG4172	Belongs to the ABC transporter superfamily
XAUT_RS13270	COG0494	nUDIX hydrolase
XAUT_RS13285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XAUT_RS13320	COG2171	N-acyltransferase activity
XAUT_RS13335	COG3093	addiction module antidote protein HigA
XAUT_RS13340	COG3549	Plasmid maintenance system killer
XAUT_RS13370	COG2801	Transposase and inactivated derivatives
XAUT_RS13380	COG1271	oxidase subunit
XAUT_RS13385	COG0583	DNA-binding transcription factor activity
XAUT_RS13390	COG2855	membrane
XAUT_RS13410	COG2963	transposase activity
XAUT_RS13415	COG2801	Transposase and inactivated derivatives
XAUT_RS13435	COG0039	L-malate dehydrogenase activity
XAUT_RS13495	COG0640	Transcriptional regulator
XAUT_RS13500	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS13515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XAUT_RS13520	COG0583	DNA-binding transcription factor activity
XAUT_RS13525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XAUT_RS13530	COG3485	protocatechuate 3,4-dioxygenase
XAUT_RS13535	COG3485	protocatechuate 3,4-dioxygenase
XAUT_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS13550	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS13565	COG1053	succinate dehydrogenase
XAUT_RS13575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS13580	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS13595	COG1053	succinate dehydrogenase
XAUT_RS13600	COG1053	succinate dehydrogenase
XAUT_RS13605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XAUT_RS13610	COG1129	ABC transporter
XAUT_RS13615	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS13650	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS13675	COG2814	Major facilitator Superfamily
XAUT_RS13685	COG0247	lactate metabolic process
XAUT_RS13690	COG0785	Cytochrome C biogenesis protein
XAUT_RS13695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAUT_RS13700	COG0424	maF-like protein
XAUT_RS13705	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XAUT_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
XAUT_RS13715	COG0500	methyltransferase
XAUT_RS13730	COG0625	glutathione transferase activity
XAUT_RS13735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XAUT_RS13755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XAUT_RS13770	COG0436	Aminotransferase
XAUT_RS13775	COG0625	glutathione transferase activity
XAUT_RS13785	COG2133	pyrroloquinoline quinone binding
XAUT_RS13805	COG0556	nucleotide-excision repair
XAUT_RS13810	COG2860	membrane
XAUT_RS13820	COG1618	nucleotide phosphatase activity, acting on free nucleotides
XAUT_RS13820	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XAUT_RS13835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XAUT_RS13840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAUT_RS13845	COG1522	sequence-specific DNA binding
XAUT_RS13850	COG0492	ferredoxin-NADP+ reductase activity
XAUT_RS13870	COG0583	DNA-binding transcription factor activity
XAUT_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS13895	COG0747	negative chemotaxis
XAUT_RS13900	COG0601	transmembrane transport
XAUT_RS13905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XAUT_RS13910	COG0444	Belongs to the ABC transporter superfamily
XAUT_RS13925	COG2072	flavoprotein involved in K transport
XAUT_RS13950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS13965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS13975	COG1595	DNA-templated transcription, initiation
XAUT_RS13985	COG4774	siderophore transport
XAUT_RS13990	COG1120	ATPase activity
XAUT_RS14000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XAUT_RS14070	COG0028	Belongs to the TPP enzyme family
XAUT_RS14085	COG1217	gtp-binding protein TYPA
XAUT_RS14090	COG0579	oxidoreductase
XAUT_RS14100	COG2081	HI0933 family
XAUT_RS14115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XAUT_RS14120	COG1414	Transcriptional regulator
XAUT_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS14140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XAUT_RS14145	COG0778	Nitroreductase
XAUT_RS14155	COG4221	oxidoreductase activity
XAUT_RS14165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XAUT_RS14190	COG0483	inositol monophosphate 1-phosphatase activity
XAUT_RS14205	COG0071	Belongs to the small heat shock protein (HSP20) family
XAUT_RS14210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XAUT_RS14230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS14250	COG2226	methyltransferase
XAUT_RS14265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XAUT_RS14270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XAUT_RS14275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XAUT_RS14300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XAUT_RS14310	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XAUT_RS14320	COG0745	RESPONSE REGULATOR receiver
XAUT_RS14325	COG2205	protein histidine kinase activity
XAUT_RS14335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAUT_RS14335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XAUT_RS14340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAUT_RS14365	COG4453	Protein conserved in bacteria
XAUT_RS14410	COG5489	Protein of unknown function (DUF736)
XAUT_RS14415	COG1476	TRANSCRIPTIONal
XAUT_RS14435	COG1192	Involved in chromosome partitioning
XAUT_RS14460	COG0741	lytic transglycosylase activity
XAUT_RS14485	COG4962	Type ii secretion system protein e
XAUT_RS14500	COG3451	type IV secretory pathway VirB4
XAUT_RS14515	COG3846	protein secretion by the type IV secretion system
XAUT_RS14530	COG2948	multi-organism process
XAUT_RS14555	COG3453	Protein conserved in bacteria
XAUT_RS14555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAUT_RS14560	COG0730	response to heat
XAUT_RS14575	COG0640	Transcriptional regulator
XAUT_RS14580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAUT_RS14585	COG2132	Multicopper oxidase
XAUT_RS14590	COG2072	flavoprotein involved in K transport
XAUT_RS14615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAUT_RS14625	COG2801	Transposase and inactivated derivatives
XAUT_RS14670	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XAUT_RS14705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XAUT_RS14715	COG2032	superoxide dismutase activity
XAUT_RS14725	COG1850	ribulose-bisphosphate carboxylase activity
XAUT_RS14750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAUT_RS14755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAUT_RS14760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS14780	COG0625	glutathione transferase activity
XAUT_RS14785	COG0583	DNA-binding transcription factor activity
XAUT_RS14800	COG3119	arylsulfatase activity
XAUT_RS14810	COG3842	ATPase activity
XAUT_RS14815	COG1176	ABC-type spermidine putrescine transport system, permease component I
XAUT_RS14820	COG1177	transmembrane transport
XAUT_RS14845	COG0714	Associated with various cellular activities
XAUT_RS14855	COG0494	nUDIX hydrolase
XAUT_RS14865	COG0617	tRNA 3'-terminal CCA addition
XAUT_RS14875	COG0408	coproporphyrinogen oxidase activity
XAUT_RS14880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XAUT_RS14890	COG0723	plastoquinol--plastocyanin reductase activity
XAUT_RS14895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XAUT_RS14895	COG2857	Cytochrome c1
XAUT_RS14900	COG2857	Cytochrome c1
XAUT_RS14900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XAUT_RS14920	COG0583	DNA-binding transcription factor activity
XAUT_RS14930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XAUT_RS14935	COG1309	transcriptional regulator
XAUT_RS14940	COG1902	pentaerythritol trinitrate reductase activity
XAUT_RS14960	COG0625	glutathione transferase activity
XAUT_RS14965	COG0625	glutathione transferase activity
XAUT_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS15000	COG0556	nucleotide-excision repair
XAUT_RS15020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XAUT_RS15045	COG0583	DNA-binding transcription factor activity
XAUT_RS15050	COG2948	multi-organism process
XAUT_RS15065	COG3846	protein secretion by the type IV secretion system
XAUT_RS15080	COG3451	type IV secretory pathway VirB4
XAUT_RS15095	COG4962	Type ii secretion system protein e
XAUT_RS15145	COG1192	Involved in chromosome partitioning
XAUT_RS15180	COG5489	Protein of unknown function (DUF736)
XAUT_RS15225	COG1475	DNA binding
XAUT_RS15240	COG4227	nucleotidyltransferase activity
XAUT_RS15255	COG4974	Belongs to the 'phage' integrase family
XAUT_RS15270	COG1959	2 iron, 2 sulfur cluster binding
XAUT_RS15275	COG2346	COG2346, Truncated hemoglobins
XAUT_RS15290	COG3256	nitric oxide reductase
XAUT_RS15310	COG1074	ATP-dependent DNA helicase activity
XAUT_RS15315	COG2176	DNA-directed DNA polymerase activity
XAUT_RS15330	COG2003	Belongs to the UPF0758 family
XAUT_RS15335	COG0024	Methionine aminopeptidase
XAUT_RS15340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XAUT_RS15345	COG0483	inositol monophosphate 1-phosphatase activity
XAUT_RS15350	COG0823	Involved in the tonB-independent uptake of proteins
XAUT_RS15365	COG0811	peptide transport
XAUT_RS15375	COG1692	metallophosphoesterase
XAUT_RS15380	COG0217	transcriptional regulatory protein
XAUT_RS15385	COG0789	Transcriptional regulator
XAUT_RS15395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XAUT_RS15405	COG0632	four-way junction helicase activity
XAUT_RS15415	COG2255	four-way junction helicase activity
XAUT_RS15430	COG0824	Thioesterase
XAUT_RS15455	COG0126	phosphoglycerate kinase activity
XAUT_RS15460	COG3588	fructose-bisphosphate aldolase
XAUT_RS15465	COG0352	thiamine-phosphate diphosphorylase activity
XAUT_RS15475	COG2885	chlorophyll binding
XAUT_RS15485	COG0037	tRNA processing
XAUT_RS15490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XAUT_RS15500	COG0180	Tryptophanyl-tRNA synthetase
XAUT_RS15505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XAUT_RS15515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XAUT_RS15525	COG1040	competence protein
XAUT_RS15535	COG1937	Protein conserved in bacteria
XAUT_RS15540	COG0742	ribosomal rna small subunit methyltransferase
XAUT_RS15545	COG1187	pseudouridine synthase activity
XAUT_RS15550	COG0590	tRNA wobble adenosine to inosine editing
XAUT_RS15560	COG0596	Alpha beta hydrolase
XAUT_RS15565	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
XAUT_RS15575	COG1489	DNA binding
XAUT_RS15600	COG2226	methyltransferase
XAUT_RS15605	COG0824	Thioesterase
XAUT_RS15620	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XAUT_RS15630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XAUT_RS15635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XAUT_RS15655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XAUT_RS15665	COG0360	Binds together with S18 to 16S ribosomal RNA
XAUT_RS15670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XAUT_RS15680	COG0359	binds to the 23S rRNA
XAUT_RS15685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XAUT_RS15705	COG0248	Ppx GppA phosphatase
XAUT_RS15710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XAUT_RS15720	COG0628	permease
XAUT_RS15730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XAUT_RS15735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XAUT_RS15740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XAUT_RS15745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XAUT_RS15750	COG1561	YicC-like family, N-terminal region
XAUT_RS15755	COG0194	GDP metabolic process
XAUT_RS15760	COG1674	ftsk spoiiie
XAUT_RS15765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XAUT_RS15775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XAUT_RS15790	COG0281	malic enzyme
XAUT_RS15790	COG0280	phosphate acetyltransferase
XAUT_RS15795	COG3161	chorismate lyase activity
XAUT_RS15825	COG4695	Portal protein
XAUT_RS15855	COG0741	lytic transglycosylase activity
XAUT_RS15990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XAUT_RS16015	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS16020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAUT_RS16025	COG0346	lactoylglutathione lyase activity
XAUT_RS16035	COG0602	queuosine metabolic process
XAUT_RS16040	COG0720	synthase
XAUT_RS16045	COG0431	NADPH-dependent FMN reductase
XAUT_RS16065	COG2132	Multicopper oxidase
XAUT_RS16075	COG0672	)-iron permease
XAUT_RS16085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XAUT_RS16090	COG4149	molybdate abc transporter
XAUT_RS16095	COG0725	ABC transporter, periplasmic molybdate-binding protein
XAUT_RS16100	COG0586	Pfam SNARE associated Golgi protein
XAUT_RS16105	COG0513	Belongs to the DEAD box helicase family
XAUT_RS16110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XAUT_RS16130	COG2267	carboxylic ester hydrolase activity
XAUT_RS16145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS16150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS16155	COG1278	Cold shock
XAUT_RS16160	COG1376	ErfK ybiS ycfS ynhG family protein
XAUT_RS16180	COG3685	Protein conserved in bacteria
XAUT_RS16190	COG0546	phosphoglycolate phosphatase activity
XAUT_RS16200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XAUT_RS16225	COG2814	Major facilitator Superfamily
XAUT_RS16230	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XAUT_RS16260	COG5265	(ABC) transporter
XAUT_RS16275	COG2205	protein histidine kinase activity
XAUT_RS16280	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XAUT_RS16285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XAUT_RS16290	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XAUT_RS16305	COG0154	amidase activity
XAUT_RS16310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAUT_RS16315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XAUT_RS16320	COG0583	DNA-binding transcription factor activity
XAUT_RS16350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XAUT_RS16370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XAUT_RS16390	COG4953	penicillin-binding protein 1C
XAUT_RS16415	COG0456	acetyltransferase
XAUT_RS16420	COG0009	L-threonylcarbamoyladenylate synthase
XAUT_RS16425	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS16440	COG1131	(ABC) transporter
XAUT_RS16445	COG0842	Transport permease protein
XAUT_RS16455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XAUT_RS16475	COG1797	cobyrinic acid a,c-diamide synthase activity
XAUT_RS16480	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
XAUT_RS16545	COG3195	allantoin biosynthetic process
XAUT_RS16545	COG3648	Uricase
XAUT_RS16550	COG2351	hydroxyisourate hydrolase activity
XAUT_RS16555	COG2233	PERMEase
XAUT_RS16560	COG0583	DNA-binding transcription factor activity
XAUT_RS16570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XAUT_RS16575	COG2205	protein histidine kinase activity
XAUT_RS16580	COG3178	'Phosphotransferase
XAUT_RS16585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XAUT_RS16590	COG2887	Belongs to the helicase family. UvrD subfamily
XAUT_RS16595	COG1074	ATP-dependent DNA helicase activity
XAUT_RS16610	COG0101	tRNA pseudouridine synthase activity
XAUT_RS16615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XAUT_RS16620	COG0242	peptide deformylase activity
XAUT_RS16630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XAUT_RS16635	COG1024	Enoyl-CoA hydratase
XAUT_RS16675	COG0433	COG0433 Predicted ATPase
XAUT_RS16705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XAUT_RS16715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XAUT_RS16720	COG2202	Pas domain
XAUT_RS16720	COG2205	protein histidine kinase activity
XAUT_RS16725	COG1525	nuclease
XAUT_RS16735	COG1234	tRNA 3'-trailer cleavage
XAUT_RS16740	COG1573	uracil-dna glycosylase
XAUT_RS16745	COG0489	protein tyrosine kinase activity
XAUT_RS16750	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XAUT_RS16755	COG0751	glycine-tRNA ligase activity
XAUT_RS16760	COG0752	glycyl-tRNA synthetase alpha subunit
XAUT_RS16770	COG0179	Fumarylacetoacetate (FAA) hydrolase
XAUT_RS16775	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XAUT_RS16785	COG4221	oxidoreductase activity
XAUT_RS16790	COG0667	Aldo Keto reductase
XAUT_RS16805	COG0789	Transcriptional regulator
XAUT_RS16845	COG0604	alcohol dehydrogenase
XAUT_RS16850	COG2186	Transcriptional regulator
XAUT_RS16865	COG1024	Enoyl-CoA hydratase
XAUT_RS16890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XAUT_RS16910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XAUT_RS16925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XAUT_RS16935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XAUT_RS16940	COG0081	regulation of translation
XAUT_RS16950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XAUT_RS16955	COG0222	ribosome binding
XAUT_RS16960	COG0085	RNA polymerase activity
XAUT_RS16965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XAUT_RS16980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XAUT_RS16985	COG3618	amidohydrolase
XAUT_RS16990	COG4948	Mandelate Racemase Muconate Lactonizing
XAUT_RS16995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XAUT_RS17000	COG2186	Transcriptional regulator
XAUT_RS17005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS17025	COG0444	Belongs to the ABC transporter superfamily
XAUT_RS17030	COG4608	Belongs to the ABC transporter superfamily
XAUT_RS17035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XAUT_RS17040	COG0601	transmembrane transport
XAUT_RS17045	COG4166	transmembrane transport
XAUT_RS17055	COG1968	undecaprenyl-diphosphatase activity
XAUT_RS17060	COG0330	HflC and HflK could
XAUT_RS17065	COG0330	HflC and HflK could
XAUT_RS17080	COG4191	Histidine kinase
XAUT_RS17085	COG4566	intracellular signal transduction
XAUT_RS17110	COG1477	protein flavinylation
XAUT_RS17155	COG0745	RESPONSE REGULATOR receiver
XAUT_RS17160	COG2205	protein histidine kinase activity
XAUT_RS17180	COG2132	Multicopper oxidase
XAUT_RS17195	COG3119	arylsulfatase activity
XAUT_RS17210	COG1566	PFAM secretion protein HlyD family protein
XAUT_RS17250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS17360	COG0582	viral genome integration into host DNA
XAUT_RS17385	COG1522	sequence-specific DNA binding
XAUT_RS17400	COG2084	Dehydrogenase
XAUT_RS17410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS17425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAUT_RS17440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS17465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS17470	COG1116	anion transmembrane transporter activity
XAUT_RS17485	COG0587	DNA-directed DNA polymerase activity
XAUT_RS17505	COG2801	Transposase and inactivated derivatives
XAUT_RS17520	COG0488	(ABC) transporter
XAUT_RS17525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAUT_RS17540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XAUT_RS17545	COG3383	formate dehydrogenase (NAD+) activity
XAUT_RS17560	COG0583	DNA-binding transcription factor activity
XAUT_RS17590	COG0745	RESPONSE REGULATOR receiver
XAUT_RS17610	COG0010	Belongs to the arginase family
XAUT_RS17615	COG0387	Pfam Sodium calcium exchanger
XAUT_RS17630	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XAUT_RS17635	COG0436	Aminotransferase
XAUT_RS17650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XAUT_RS17655	COG0511	ligase activity, forming carbon-carbon bonds
XAUT_RS17675	COG1012	belongs to the aldehyde dehydrogenase family
XAUT_RS17685	COG2423	ornithine cyclodeaminase activity
XAUT_RS17690	COG0386	Belongs to the glutathione peroxidase family
XAUT_RS17700	COG0145	ligase activity
XAUT_RS17705	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
XAUT_RS17710	COG4647	ligase activity
XAUT_RS17725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XAUT_RS17735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XAUT_RS17740	COG0745	RESPONSE REGULATOR receiver
XAUT_RS17750	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XAUT_RS17755	COG1494	fructose-1,6-bisphosphatase
XAUT_RS17765	COG0436	Aminotransferase
XAUT_RS17775	COG3243	poly(R)-hydroxyalkanoic acid synthase
XAUT_RS17785	COG0612	Peptidase, M16
XAUT_RS17795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAUT_RS17800	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XAUT_RS17805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XAUT_RS17830	COG1181	Belongs to the D-alanine--D-alanine ligase family
XAUT_RS17840	COG0537	adenosine 5'-monophosphoramidase activity
XAUT_RS17845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XAUT_RS17860	COG2308	Evidence 4 Homologs of previously reported genes of
XAUT_RS17865	COG1546	Belongs to the CinA family
XAUT_RS17865	COG1058	Belongs to the CinA family
XAUT_RS17900	COG1088	dTDP-glucose 4,6-dehydratase activity
XAUT_RS17905	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XAUT_RS17910	COG2942	2-epimerase
XAUT_RS17920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XAUT_RS17925	COG0489	protein tyrosine kinase activity
XAUT_RS17925	COG3206	protein involved in exopolysaccharide biosynthesis
XAUT_RS17930	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XAUT_RS17935	COG1088	dTDP-glucose 4,6-dehydratase activity
XAUT_RS17940	COG1091	dTDP-4-dehydrorhamnose reductase activity
XAUT_RS17945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XAUT_RS17950	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS17970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS17985	COG1045	serine acetyltransferase
XAUT_RS18010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS18015	COG1045	serine acetyltransferase
XAUT_RS18030	COG1393	Belongs to the ArsC family
XAUT_RS18040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XAUT_RS18090	COG0174	glutamine synthetase
XAUT_RS18095	COG0347	Belongs to the P(II) protein family
XAUT_RS18100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XAUT_RS18100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XAUT_RS18125	COG0544	peptidyl-prolyl cis-trans isomerase activity
XAUT_RS18130	COG0740	serine-type endopeptidase activity
XAUT_RS18135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XAUT_RS18140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XAUT_RS18145	COG0776	regulation of translation
XAUT_RS18195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAUT_RS18195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAUT_RS18320	COG0629	single-stranded DNA binding
XAUT_RS18380	COG3566	protein conserved in bacteria
XAUT_RS18515	COG3179	chitinase
XAUT_RS18725	COG3750	Belongs to the UPF0335 family
XAUT_RS18730	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
XAUT_RS18740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XAUT_RS18785	COG4695	Portal protein
XAUT_RS18940	COG2801	Transposase and inactivated derivatives
XAUT_RS19000	COG0400	carboxylic ester hydrolase activity
XAUT_RS19005	COG0346	lactoylglutathione lyase activity
XAUT_RS19030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAUT_RS19035	COG0625	glutathione transferase activity
XAUT_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS19055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAUT_RS19070	COG4149	molybdate abc transporter
XAUT_RS19075	COG1840	ABC-type Fe3 transport system, periplasmic component
XAUT_RS19115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XAUT_RS19115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XAUT_RS19140	COG1492	cobalamin metabolic process
XAUT_RS19150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XAUT_RS19170	COG3768	UPF0283 membrane protein
XAUT_RS19175	COG0785	Cytochrome C biogenesis protein
XAUT_RS19180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XAUT_RS19185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XAUT_RS19225	COG1254	Belongs to the acylphosphatase family
XAUT_RS19235	COG0456	acetyltransferase
XAUT_RS19240	COG0625	glutathione transferase activity
XAUT_RS19260	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS19265	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS19270	COG0156	8-amino-7-oxononanoate synthase activity
XAUT_RS19275	COG3321	synthase
XAUT_RS19275	COG0604	alcohol dehydrogenase
XAUT_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS19310	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS19315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAUT_RS19320	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS19350	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS19355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XAUT_RS19370	COG3047	cAMP biosynthetic process
XAUT_RS19370	COG2885	chlorophyll binding
XAUT_RS19380	COG0741	lytic transglycosylase activity
XAUT_RS19385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XAUT_RS19400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XAUT_RS19415	COG1573	uracil-dna glycosylase
XAUT_RS19425	COG1758	RNA polymerase activity
XAUT_RS19440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAUT_RS19450	COG0400	carboxylic ester hydrolase activity
XAUT_RS19460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XAUT_RS19485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XAUT_RS19500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XAUT_RS19505	COG4133	protoheme IX ABC transporter activity
XAUT_RS19510	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XAUT_RS19515	COG2005	Transcriptional regulator
XAUT_RS19515	COG3585	molybdate ion transport
XAUT_RS19525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XAUT_RS19535	COG0784	Response regulator, receiver
XAUT_RS19540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XAUT_RS19560	COG0557	exoribonuclease II activity
XAUT_RS19575	COG4166	transmembrane transport
XAUT_RS19590	COG2301	Belongs to the HpcH HpaI aldolase family
XAUT_RS19605	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS19610	COG1253	flavin adenine dinucleotide binding
XAUT_RS19615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS19620	COG0679	Auxin Efflux Carrier
XAUT_RS19630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XAUT_RS19635	COG0736	holo-[acyl-carrier-protein] synthase activity
XAUT_RS19640	COG0681	Belongs to the peptidase S26 family
XAUT_RS19645	COG0571	ribonuclease III activity
XAUT_RS19650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XAUT_RS19660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XAUT_RS19665	COG1381	Involved in DNA repair and RecF pathway recombination
XAUT_RS19675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XAUT_RS19685	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAUT_RS19685	COG0022	dehydrogenase e1 component
XAUT_RS19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAUT_RS19705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAUT_RS19710	COG2261	transglycosylase associated protein
XAUT_RS19720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XAUT_RS19725	COG2867	negative regulation of translational initiation
XAUT_RS19730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XAUT_RS19760	COG0683	leucine binding
XAUT_RS19775	COG1509	lysine 2,3-aminomutase activity
XAUT_RS19785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XAUT_RS19785	COG3608	succinylglutamate desuccinylase aspartoacylase
XAUT_RS19790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XAUT_RS19805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XAUT_RS19815	COG0758	DNA mediated transformation
XAUT_RS19825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XAUT_RS19830	COG0540	Belongs to the ATCase OTCase family
XAUT_RS19845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XAUT_RS19860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XAUT_RS19865	COG0154	amidase activity
XAUT_RS19875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XAUT_RS19880	COG1304	FMN binding
XAUT_RS19885	COG2186	Transcriptional regulator
XAUT_RS19910	COG4191	Histidine kinase
XAUT_RS19920	COG0281	malic enzyme
XAUT_RS19940	COG0640	Transcriptional regulator
XAUT_RS19960	COG0183	Belongs to the thiolase family
XAUT_RS19975	COG2204	response regulator
XAUT_RS19995	COG1910	domain protein
XAUT_RS20005	COG0573	inorganic phosphate transmembrane transporter activity
XAUT_RS20010	COG0573	inorganic phosphate transmembrane transporter activity
XAUT_RS20015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XAUT_RS20030	COG0798	PFAM Bile acid sodium symporter
XAUT_RS20035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XAUT_RS20050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XAUT_RS20055	COG3639	organic phosphonate transmembrane transporter activity
XAUT_RS20095	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS20130	COG0789	Transcriptional regulator
XAUT_RS20140	COG1538	Outer membrane efflux protein
XAUT_RS20150	COG0347	Belongs to the P(II) protein family
XAUT_RS20205	COG3451	type IV secretory pathway VirB4
XAUT_RS20220	COG4962	Type ii secretion system protein e
XAUT_RS20245	COG2801	Transposase and inactivated derivatives
XAUT_RS20290	COG1192	Involved in chromosome partitioning
XAUT_RS20315	COG1476	TRANSCRIPTIONal
XAUT_RS20320	COG5489	Protein of unknown function (DUF736)
XAUT_RS20340	COG1475	DNA binding
XAUT_RS20385	COG4302	ethanolamine ammonia-lyase activity
XAUT_RS20390	COG4303	Ethanolamine ammonia lyase large subunit
XAUT_RS20395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS20410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XAUT_RS20420	COG1063	alcohol dehydrogenase
XAUT_RS20425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XAUT_RS20435	COG0596	Alpha beta hydrolase
XAUT_RS20435	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAUT_RS20440	COG0022	dehydrogenase e1 component
XAUT_RS20445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XAUT_RS20450	COG3284	Transcriptional regulator
XAUT_RS20455	COG3246	L-lysine catabolic process to acetate
XAUT_RS20465	COG4191	Histidine kinase
XAUT_RS20470	COG1116	anion transmembrane transporter activity
XAUT_RS20475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAUT_RS20495	COG0411	ABC transporter
XAUT_RS20505	COG0154	amidase activity
XAUT_RS20515	COG0583	DNA-binding transcription factor activity
XAUT_RS20540	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XAUT_RS20545	COG0154	amidase activity
XAUT_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS20575	COG2030	dehydratase
XAUT_RS20590	COG1309	transcriptional regulator
XAUT_RS20605	COG0604	alcohol dehydrogenase
XAUT_RS20605	COG3321	synthase
XAUT_RS20605	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS20630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XAUT_RS20650	COG2239	Acts as a magnesium transporter
XAUT_RS20655	COG5001	Diguanylate cyclase
XAUT_RS20655	COG3300	MHYT domain
XAUT_RS20660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XAUT_RS20670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XAUT_RS20680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XAUT_RS20685	COG0047	phosphoribosylformylglycinamidine synthase activity
XAUT_RS20690	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XAUT_RS20695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XAUT_RS20705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XAUT_RS20710	COG1971	Probably functions as a manganese efflux pump
XAUT_RS20720	COG1891	lyase activity
XAUT_RS20755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XAUT_RS20760	COG0179	Fumarylacetoacetate (FAA) hydrolase
XAUT_RS20775	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS20785	COG2814	Major facilitator Superfamily
XAUT_RS20790	COG4948	Mandelate Racemase Muconate Lactonizing
XAUT_RS20795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XAUT_RS20800	COG1127	ABC transporter
XAUT_RS20815	COG3106	COG3106 Predicted ATPase
XAUT_RS20835	COG3191	aminopeptidase activity
XAUT_RS20850	COG0633	Ferredoxin
XAUT_RS20880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAUT_RS20885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XAUT_RS20895	COG1131	(ABC) transporter
XAUT_RS20905	COG1304	FMN binding
XAUT_RS20925	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XAUT_RS20930	COG1253	flavin adenine dinucleotide binding
XAUT_RS20940	COG0406	alpha-ribazole phosphatase activity
XAUT_RS20950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XAUT_RS20975	COG2239	Acts as a magnesium transporter
XAUT_RS20990	COG0559	Belongs to the binding-protein-dependent transport system permease family
XAUT_RS21010	COG0829	nickel cation binding
XAUT_RS21015	COG0832	Belongs to the urease beta subunit family
XAUT_RS21015	COG0831	urea catabolic process
XAUT_RS21020	COG0804	urea catabolic process
XAUT_RS21025	COG0783	Belongs to the Dps family
XAUT_RS21030	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
XAUT_RS21035	COG0830	nickel cation binding
XAUT_RS21040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XAUT_RS21060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XAUT_RS21075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS21080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS21085	COG1538	Outer membrane efflux protein
XAUT_RS21115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XAUT_RS21185	COG5265	(ABC) transporter
XAUT_RS21195	COG4941	Belongs to the sigma-70 factor family
XAUT_RS21200	COG3795	YCII-related domain
XAUT_RS21205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
XAUT_RS21210	COG2329	Antibiotic biosynthesis monooxygenase
XAUT_RS21215	COG4771	TonB-dependent receptor
XAUT_RS21220	COG4558	Periplasmic binding protein
XAUT_RS21225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XAUT_RS21230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XAUT_RS21235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XAUT_RS21245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XAUT_RS21260	COG0504	CTP synthase activity
XAUT_RS21270	COG2076	Multidrug Resistance protein
XAUT_RS21305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAUT_RS21305	COG2010	Cytochrome c
XAUT_RS21310	COG2080	2 iron, 2 sulfur cluster binding
XAUT_RS21355	COG1846	Transcriptional regulator
XAUT_RS21370	COG0583	DNA-binding transcription factor activity
XAUT_RS21375	COG1283	sodium-dependent phosphate transmembrane transporter activity
XAUT_RS21380	COG0729	surface antigen
XAUT_RS21395	COG4591	ABC-type transport system involved in lipoprotein release permease component
XAUT_RS21400	COG1136	(ABC) transporter
XAUT_RS21405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XAUT_RS21415	COG1132	(ABC) transporter
XAUT_RS21425	COG0463	Glycosyl transferase, family 2
XAUT_RS21425	COG1216	Glycosyl transferase, family 2
XAUT_RS21435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XAUT_RS21450	COG0525	valine-tRNA ligase activity
XAUT_RS21480	COG0316	Belongs to the HesB IscA family
XAUT_RS21485	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XAUT_RS21490	COG0018	arginyl-trna synthetase
XAUT_RS21515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XAUT_RS21525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XAUT_RS21540	COG0656	L-ascorbic acid biosynthetic process
XAUT_RS21565	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XAUT_RS21570	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XAUT_RS21575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XAUT_RS21585	COG0459	protein refolding
XAUT_RS21590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XAUT_RS21595	COG5425	PFAM Usg family protein
XAUT_RS21600	COG0693	protein deglycase activity
XAUT_RS21615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XAUT_RS21620	COG0343	queuine tRNA-ribosyltransferase activity
XAUT_RS21625	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS21635	COG0848	biopolymer transport protein
XAUT_RS21640	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XAUT_RS21645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XAUT_RS21650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XAUT_RS21655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAUT_RS21655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAUT_RS21665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XAUT_RS21670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XAUT_RS21675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XAUT_RS21695	COG0628	permease
XAUT_RS21710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XAUT_RS21715	COG0148	phosphopyruvate hydratase activity
XAUT_RS21720	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS21725	COG2095	MarC family integral membrane protein
XAUT_RS21730	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XAUT_RS21740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XAUT_RS21745	COG0113	porphobilinogen synthase activity
XAUT_RS21750	COG1024	Enoyl-CoA hydratase
XAUT_RS21760	COG4122	O-methyltransferase activity
XAUT_RS21770	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS21780	COG0134	indole-3-glycerol-phosphate synthase activity
XAUT_RS21790	COG0574	Belongs to the PEP-utilizing enzyme family
XAUT_RS21790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XAUT_RS21800	COG0514	ATP-dependent DNA helicase (RecQ)
XAUT_RS21805	COG1546	Belongs to the CinA family
XAUT_RS21805	COG1058	Belongs to the CinA family
XAUT_RS21810	COG1862	Preprotein translocase
XAUT_RS21815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XAUT_RS21825	COG3737	Protein of unknown function (DUF498/DUF598)
XAUT_RS21840	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
XAUT_RS21845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XAUT_RS21850	COG0629	single-stranded DNA binding
XAUT_RS21860	COG1280	lysine exporter protein (LysE YggA)
XAUT_RS21865	COG0837	glucose binding
XAUT_RS21870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAUT_RS21895	COG1686	Belongs to the peptidase S11 family
XAUT_RS21900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XAUT_RS21905	COG0470	DNA polymerase III
XAUT_RS21920	COG1268	BioY protein
XAUT_RS21925	COG0084	hydrolase, TatD family'
XAUT_RS21930	COG1832	CoA-binding protein
XAUT_RS21945	COG2873	o-acetylhomoserine
XAUT_RS21955	COG0583	DNA-binding transcription factor activity
XAUT_RS21960	COG1380	Effector of murein hydrolase LrgA
XAUT_RS21965	COG1346	cytolysis
XAUT_RS21970	COG1612	heme a metabolic process
XAUT_RS21985	COG1024	Enoyl-CoA hydratase
XAUT_RS22000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XAUT_RS22005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XAUT_RS22025	COG0628	permease
XAUT_RS22030	COG1620	l-lactate permease
XAUT_RS22055	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS22060	COG2271	Major facilitator Superfamily
XAUT_RS22110	COG4178	(ABC) transporter
XAUT_RS22120	COG1473	amidohydrolase
XAUT_RS22125	COG0425	Belongs to the sulfur carrier protein TusA family
XAUT_RS22130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAUT_RS22140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XAUT_RS22145	COG0303	'Molybdopterin
XAUT_RS22150	COG0315	cyclic pyranopterin monophosphate synthase activity
XAUT_RS22160	COG0134	indole-3-glycerol-phosphate synthase activity
XAUT_RS22165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XAUT_RS22175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XAUT_RS22185	COG0149	triose-phosphate isomerase activity
XAUT_RS22205	COG0416	fatty acid biosynthetic process
XAUT_RS22210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XAUT_RS22215	COG0776	regulation of translation
XAUT_RS22225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XAUT_RS22235	COG0321	lipoyl(octanoyl) transferase activity
XAUT_RS22235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XAUT_RS22245	COG3956	TIGRFAM MazG family protein
XAUT_RS22250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XAUT_RS22255	COG1923	regulation of RNA biosynthetic process
XAUT_RS22260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XAUT_RS22270	COG0569	domain protein
XAUT_RS22275	COG2204	response regulator
XAUT_RS22280	COG5000	phosphorelay sensor kinase activity
XAUT_RS22285	COG2204	response regulator
XAUT_RS22295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XAUT_RS22300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XAUT_RS22300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XAUT_RS22305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XAUT_RS22310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XAUT_RS22315	COG0805	protein transport
XAUT_RS22320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XAUT_RS22325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XAUT_RS22335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XAUT_RS22340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XAUT_RS22345	COG1472	Belongs to the glycosyl hydrolase 3 family
XAUT_RS22360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XAUT_RS22365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XAUT_RS22370	COG2832	Protein of unknown function (DUF454)
XAUT_RS22375	COG3706	GGDEF domain
XAUT_RS22380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XAUT_RS22385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XAUT_RS22405	COG1215	transferase activity, transferring glycosyl groups
XAUT_RS22410	COG0746	molybdenum cofactor guanylyltransferase activity
XAUT_RS22420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAUT_RS22425	COG3494	Protein of unknown function (DUF1009)
XAUT_RS22430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAUT_RS22435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XAUT_RS22440	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAUT_RS22445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAUT_RS22450	COG0750	zinc metalloprotease
XAUT_RS22455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XAUT_RS22465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XAUT_RS22470	COG0233	cytoplasmic translational termination
XAUT_RS22475	COG0528	UMP kinase activity
XAUT_RS22480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XAUT_RS22485	COG0052	Belongs to the universal ribosomal protein uS2 family
XAUT_RS22490	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS22505	COG0183	Belongs to the thiolase family
XAUT_RS22510	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAUT_RS22510	COG1024	Enoyl-CoA hydratase
XAUT_RS22515	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS22525	COG2755	lipolytic protein G-D-S-L family
XAUT_RS22525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XAUT_RS22530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XAUT_RS22530	COG2755	lipolytic protein G-D-S-L family
XAUT_RS22545	COG0395	ABC-type sugar transport system, permease component
XAUT_RS22555	COG0351	phosphomethylpyrimidine kinase
XAUT_RS22560	COG1396	sequence-specific DNA binding
XAUT_RS22590	COG1136	(ABC) transporter
XAUT_RS22600	COG0442	prolyl-tRNA aminoacylation
XAUT_RS22610	COG2151	metal-sulfur cluster biosynthetic enzyme
XAUT_RS22615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XAUT_RS22620	COG0719	Fe-S assembly protein
XAUT_RS22625	COG0396	ATPase activity
XAUT_RS22630	COG0719	Fe-S assembly protein
XAUT_RS22635	COG1104	cysteine desulfurase activity
XAUT_RS22640	COG2945	thiolester hydrolase activity
XAUT_RS22645	COG0531	amino acid
XAUT_RS22650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XAUT_RS22655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XAUT_RS22660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XAUT_RS22665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XAUT_RS22700	COG3299	homolog of phage Mu protein gp47
XAUT_RS22775	COG4397	Mu-like prophage major head subunit gpT
XAUT_RS22805	COG4383	Mu-like prophage protein gp29
XAUT_RS22910	COG2842	Transposition protein
XAUT_RS22915	COG2801	Transposase and inactivated derivatives
XAUT_RS22955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XAUT_RS22960	COG2154	pterin-4-alpha-carbinolamine dehydratase
XAUT_RS22975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XAUT_RS22985	COG1686	Belongs to the peptidase S11 family
XAUT_RS23000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XAUT_RS23010	COG3781	membrane
XAUT_RS23015	COG0626	cystathionine gamma-synthase activity
XAUT_RS23020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XAUT_RS23025	COG4597	amino acid ABC transporter
XAUT_RS23030	COG0765	amino acid transport
XAUT_RS23035	COG1126	abc transporter atp-binding protein
XAUT_RS23050	COG0671	phosphoesterase, PA-phosphatase related
XAUT_RS23055	COG0463	Glycosyl transferase, family 2
XAUT_RS23065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS23070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAUT_RS23075	COG0436	Aminotransferase
XAUT_RS23085	COG3263	regulation of cellular component size
XAUT_RS23105	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XAUT_RS23110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XAUT_RS23130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAUT_RS23135	COG0538	isocitrate dehydrogenase activity
XAUT_RS23200	COG1475	DNA binding
XAUT_RS23260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAUT_RS23285	COG3436	PFAM IS66 Orf2 family protein
XAUT_RS23290	COG2433	Pfam Transposase IS66
XAUT_RS23335	COG4372	Transposase
XAUT_RS23340	COG4372	Transposase
XAUT_RS23345	COG3436	PFAM IS66 Orf2 family protein
XAUT_RS23370	COG0316	Belongs to the HesB IscA family
XAUT_RS23385	COG0346	lactoylglutathione lyase activity
XAUT_RS23400	COG1007	ATP synthesis coupled electron transport
XAUT_RS23415	COG0713	ATP synthesis coupled electron transport
XAUT_RS23425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAUT_RS23430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XAUT_RS23440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XAUT_RS23450	COG0649	NAD binding
XAUT_RS23455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAUT_RS23460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAUT_RS23490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XAUT_RS23505	COG3346	SURF1 family
XAUT_RS23520	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XAUT_RS23530	COG0109	protoheme IX farnesyltransferase activity
XAUT_RS23535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XAUT_RS23540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XAUT_RS23565	COG0583	DNA-binding transcription factor activity
XAUT_RS23570	COG1802	Transcriptional regulator
XAUT_RS23590	COG4172	Belongs to the ABC transporter superfamily
XAUT_RS23595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XAUT_RS23605	COG0747	negative chemotaxis
XAUT_RS23610	COG1183	phosphatidylcholine synthase activity
XAUT_RS23615	COG0688	phosphatidylethanolamine metabolic process
XAUT_RS23630	COG0183	Belongs to the thiolase family
XAUT_RS23635	COG1960	acyl-CoA dehydrogenase activity
XAUT_RS23640	COG0860	N-Acetylmuramoyl-L-alanine amidase
XAUT_RS23645	COG1530	ribonuclease E activity
XAUT_RS23645	COG1530	ribonuclease E activity
XAUT_RS23650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XAUT_RS23655	COG2199	diguanylate cyclase activity
XAUT_RS23655	COG2200	EAL domain
XAUT_RS23655	COG2202	Pas domain
XAUT_RS23675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XAUT_RS23680	COG0477	Major facilitator Superfamily
XAUT_RS23685	COG0415	Belongs to the DNA photolyase family
XAUT_RS23690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XAUT_RS23695	COG2897	thiosulfate sulfurtransferase activity
XAUT_RS23710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XAUT_RS23715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XAUT_RS23720	COG0625	glutathione transferase activity
XAUT_RS23760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XAUT_RS23790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XAUT_RS23795	COG2218	PFAM glutamate synthase alpha subunit domain protein
XAUT_RS23800	COG0069	glutamate synthase activity
XAUT_RS23805	COG0174	glutamine synthetase
XAUT_RS23810	COG0583	DNA-binding transcription factor activity
XAUT_RS23815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAUT_RS23825	COG0446	pyridine nucleotide-disulphide oxidoreductase
XAUT_RS23825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAUT_RS23860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XAUT_RS23865	COG0803	Belongs to the bacterial solute-binding protein 9 family
XAUT_RS23870	COG0523	cobalamin synthesis protein
XAUT_RS23875	COG1309	transcriptional regulator
XAUT_RS23895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XAUT_RS23905	COG0215	cysteine-tRNA ligase activity
XAUT_RS23915	COG3045	CreA protein
XAUT_RS23920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XAUT_RS23930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAUT_RS23930	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XAUT_RS23940	COG1396	sequence-specific DNA binding
XAUT_RS23940	COG3800	Transcriptional regulator
XAUT_RS23945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XAUT_RS23950	COG4770	biotin carboxylase activity
XAUT_RS23960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XAUT_RS23985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XAUT_RS24010	COG1609	Transcriptional regulator
XAUT_RS24015	COG3485	protocatechuate 3,4-dioxygenase
XAUT_RS24025	COG3246	L-lysine catabolic process to acetate
XAUT_RS24040	COG1301	dicarboxylic acid transport
XAUT_RS24045	COG1722	exodeoxyribonuclease VII activity
XAUT_RS24055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XAUT_RS24065	COG0308	aminopeptidase N
XAUT_RS24090	COG1192	Involved in chromosome partitioning
XAUT_RS24095	COG2610	gluconate transmembrane transporter activity
XAUT_RS24100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XAUT_RS24105	COG0187	DNA topoisomerase II activity
XAUT_RS24115	COG0513	Belongs to the DEAD box helicase family
XAUT_RS24130	COG0546	phosphoglycolate phosphatase activity
XAUT_RS24140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XAUT_RS24155	COG0564	pseudouridine synthase activity
XAUT_RS24160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XAUT_RS24170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XAUT_RS24180	COG0535	radical SAM domain protein
XAUT_RS24185	COG0203	ribosomal protein L17
XAUT_RS24190	COG0202	RNA polymerase activity
XAUT_RS24195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XAUT_RS24200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XAUT_RS24210	COG0563	adenylate kinase activity
XAUT_RS24215	COG0201	protein transport
XAUT_RS24220	COG0200	Binds to the 23S rRNA
XAUT_RS24225	COG1841	ribosomal large subunit assembly
XAUT_RS24230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XAUT_RS24235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XAUT_RS24240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XAUT_RS24245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XAUT_RS24250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XAUT_RS24255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XAUT_RS24260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XAUT_RS24285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XAUT_RS24745	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XAUT_RS25060	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
XAUT_RS25060	COG3261	NADH dehydrogenase
XAUT_RS25065	COG0649	NAD binding
XAUT_RS25085	COG0246	Mannitol dehydrogenase
XAUT_RS25305	COG0842	Transport permease protein
XAUT_RS25305	COG1129	ABC transporter
XAUT_RS25875	COG0552	protein localization to endoplasmic reticulum
XAUT_RS25885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XAUT_RS25900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAUT_RS25915	COG3979	chitinase
XAUT_RS25935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XAUT_RS25940	COG0604	alcohol dehydrogenase
XAUT_RS25940	COG3321	synthase
XAUT_RS25950	COG3321	synthase
XAUT_RS25950	COG1028	Short-chain dehydrogenase reductase Sdr
XAUT_RS25950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XAUT_RS25950	COG0318	PFAM AMP-dependent synthetase and ligase
XAUT_RS25950	COG0300	oxidoreductase activity
XAUT_RS26035	COG2010	Cytochrome c
XAUT_RS26035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAUT_RS26060	COG0784	Response regulator, receiver
XAUT_RS26060	COG4191	Histidine kinase
XAUT_RS26095	COG1525	nuclease
XAUT_RS26100	COG2267	carboxylic ester hydrolase activity
XAUT_RS26110	COG2770	Histidine kinase
XAUT_RS26110	COG2208	phosphoserine phosphatase activity
XAUT_RS26120	COG3409	Peptidoglycan-binding domain 1 protein
XAUT_RS26120	COG3773	Cell wall hydrolase
XAUT_RS26165	COG0726	polysaccharide deacetylase
XAUT_RS26170	COG5001	Diguanylate cyclase
XAUT_RS26180	COG0438	transferase activity, transferring glycosyl groups
XAUT_RS26180	COG1216	Glycosyl transferase, family 2
XAUT_RS26195	COG0861	Integral membrane protein TerC family
XAUT_RS26205	COG0726	polysaccharide deacetylase
XAUT_RS26215	COG1396	sequence-specific DNA binding