locus-tag	class	description
D7006_RS00010	COG0268	Binds directly to 16S ribosomal RNA
D7006_RS00020	COG0135	phosphoribosylanthranilate isomerase activity
D7006_RS00025	COG0133	tryptophan synthase activity
D7006_RS00035	COG0159	tryptophan synthase activity
D7006_RS00040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D7006_RS00050	COG0129	dihydroxy-acid dehydratase activity
D7006_RS00070	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D7006_RS00075	COG1877	trehalose-phosphatase activity
D7006_RS00090	COG5487	UPF0391 membrane protein
D7006_RS00115	COG0427	acetyl-CoA hydrolase
D7006_RS00120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7006_RS00125	COG3093	addiction module antidote protein HigA
D7006_RS00155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS00165	COG1278	Cold shock
D7006_RS00175	COG0778	Nitroreductase
D7006_RS00200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D7006_RS00205	COG3158	transport of potassium into the cell
D7006_RS00220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7006_RS00220	COG0519	Catalyzes the synthesis of GMP from XMP
D7006_RS00230	COG0069	glutamate synthase activity
D7006_RS00245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7006_RS00250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D7006_RS00255	COG3038	cytochrome b561
D7006_RS00260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7006_RS00260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7006_RS00275	COG0670	Belongs to the BI1 family
D7006_RS00285	COG0697	spore germination
D7006_RS00290	COG0583	DNA-binding transcription factor activity
D7006_RS00295	COG0837	glucose binding
D7006_RS00320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D7006_RS00335	COG1051	belongs to the nudix hydrolase family
D7006_RS00345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D7006_RS00360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D7006_RS00365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D7006_RS00370	COG0799	negative regulation of ribosome biogenesis
D7006_RS00375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D7006_RS00380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D7006_RS00400	COG3750	Belongs to the UPF0335 family
D7006_RS00405	COG3108	Peptidase M15
D7006_RS00410	COG2989	Protein conserved in bacteria
D7006_RS00415	COG0745	RESPONSE REGULATOR receiver
D7006_RS00430	COG0793	Belongs to the peptidase S41A family
D7006_RS00440	COG0765	amino acid transport
D7006_RS00445	COG0765	amino acid transport
D7006_RS00455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D7006_RS00460	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D7006_RS00465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D7006_RS00470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D7006_RS00480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D7006_RS00485	COG0590	tRNA wobble adenosine to inosine editing
D7006_RS00490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7006_RS00505	COG1116	anion transmembrane transporter activity
D7006_RS00510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D7006_RS00525	COG2855	membrane
D7006_RS00530	COG0583	DNA-binding transcription factor activity
D7006_RS00535	COG0488	(ABC) transporter
D7006_RS00540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS00545	COG1946	Acyl-CoA thioesterase
D7006_RS00550	COG0347	Belongs to the P(II) protein family
D7006_RS00555	COG0004	ammonium transporteR
D7006_RS00560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D7006_RS00565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D7006_RS00575	COG0612	Peptidase, M16
D7006_RS00580	COG0612	Peptidase, M16
D7006_RS00595	COG1607	acyl-coa hydrolase
D7006_RS00600	COG1643	Atp-dependent helicase
D7006_RS00610	COG4689	acetoacetate decarboxylase
D7006_RS00660	COG0156	8-amino-7-oxononanoate synthase activity
D7006_RS00665	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7006_RS00670	COG3842	ATPase activity
D7006_RS00675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D7006_RS00680	COG4149	molybdate abc transporter
D7006_RS00690	COG1609	Transcriptional regulator
D7006_RS00710	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS00715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D7006_RS00720	COG2086	electron transfer activity
D7006_RS00740	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D7006_RS00755	COG2183	response to ionizing radiation
D7006_RS00795	COG0375	protein maturation
D7006_RS00855	COG1764	response to oxidative stress
D7006_RS00860	COG1846	Transcriptional regulator
D7006_RS00870	COG2205	protein histidine kinase activity
D7006_RS00880	COG2226	methyltransferase
D7006_RS00885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D7006_RS00890	COG0528	UMP kinase activity
D7006_RS00895	COG0528	UMP kinase activity
D7006_RS00900	COG2223	nitrite transmembrane transporter activity
D7006_RS00910	COG3852	Histidine kinase
D7006_RS00925	COG0494	nUDIX hydrolase
D7006_RS00930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D7006_RS00935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D7006_RS00940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D7006_RS00950	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D7006_RS00955	COG1137	ATPase activity
D7006_RS00960	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D7006_RS00990	COG0745	RESPONSE REGULATOR receiver
D7006_RS00995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D7006_RS01015	COG1360	Flagellar Motor Protein
D7006_RS01030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D7006_RS01035	COG1338	Plays a role in the flagellum-specific transport system
D7006_RS01045	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D7006_RS01055	COG1706	bacterial-type flagellum-dependent cell motility
D7006_RS01065	COG4786	Flagellar basal body rod
D7006_RS01070	COG1677	Flagellar hook-basal body complex protein FliE
D7006_RS01075	COG1558	bacterial-type flagellum-dependent cell motility
D7006_RS01080	COG1815	bacterial-type flagellum-dependent cell motility
D7006_RS01090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D7006_RS01095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D7006_RS01100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D7006_RS01115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D7006_RS01125	COG4786	Flagellar basal body rod
D7006_RS01130	COG1157	protein secretion by the type III secretion system
D7006_RS01135	COG1749	Flagellar hook protein flgE
D7006_RS01155	COG5443	negative regulation of bacterial-type flagellum assembly
D7006_RS01160	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D7006_RS01165	COG1987	bacterial-type flagellum assembly
D7006_RS01170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D7006_RS01175	COG1684	flagellar biosynthetic protein fliR
D7006_RS01200	COG0643	Histidine kinase
D7006_RS01200	COG0784	Response regulator, receiver
D7006_RS01200	COG2198	Histidine kinase
D7006_RS01205	COG0835	chemotaxis
D7006_RS01210	COG0745	RESPONSE REGULATOR receiver
D7006_RS01215	COG2201	protein-glutamate methylesterase activity
D7006_RS01230	COG0840	transmembrane signaling receptor activity
D7006_RS01235	COG4566	intracellular signal transduction
D7006_RS01270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D7006_RS01275	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D7006_RS01305	COG0154	amidase activity
D7006_RS01330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7006_RS01345	COG1024	Enoyl-CoA hydratase
D7006_RS01355	COG1902	pentaerythritol trinitrate reductase activity
D7006_RS01360	COG1309	transcriptional regulator
D7006_RS01365	COG4670	ketone body catabolic process
D7006_RS01375	COG0625	glutathione transferase activity
D7006_RS01380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D7006_RS01390	COG0574	Belongs to the PEP-utilizing enzyme family
D7006_RS01390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7006_RS01405	COG2032	superoxide dismutase activity
D7006_RS01420	COG0644	oxidoreductase
D7006_RS01425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS01455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS01460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D7006_RS01465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D7006_RS01480	COG2203	Gaf domain
D7006_RS01480	COG3706	GGDEF domain
D7006_RS01480	COG4251	negative regulation of phosphorylation
D7006_RS01480	COG5001	Diguanylate cyclase
D7006_RS01485	COG0129	dihydroxy-acid dehydratase activity
D7006_RS01500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D7006_RS01525	COG0756	dUTP diphosphatase activity
D7006_RS01530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D7006_RS01535	COG3300	MHYT domain
D7006_RS01535	COG5001	Diguanylate cyclase
D7006_RS01540	COG3604	Transcriptional regulator
D7006_RS01545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7006_RS01550	COG0719	Fe-S assembly protein
D7006_RS01555	COG0396	ATPase activity
D7006_RS01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7006_RS01570	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
D7006_RS01580	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D7006_RS01585	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D7006_RS01590	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D7006_RS01605	COG5420	small protein containing a coiled-coil domain
D7006_RS01630	COG2897	thiosulfate sulfurtransferase activity
D7006_RS01655	COG0316	Belongs to the HesB IscA family
D7006_RS01665	COG1104	cysteine desulfurase activity
D7006_RS01685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7006_RS01705	COG5554	nitrogen fixation
D7006_RS01725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D7006_RS01740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D7006_RS01760	COG2151	metal-sulfur cluster biosynthetic enzyme
D7006_RS01780	COG2346	COG2346, Truncated hemoglobins
D7006_RS01805	COG0412	Dienelactone hydrolase
D7006_RS01815	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D7006_RS01820	COG0644	oxidoreductase
D7006_RS01825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D7006_RS01830	COG2086	electron transfer activity
D7006_RS01835	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
D7006_RS01860	COG0157	Belongs to the NadC ModD family
D7006_RS01880	COG0039	L-malate dehydrogenase activity
D7006_RS01885	COG0045	succinate-CoA ligase (ADP-forming) activity
D7006_RS01890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D7006_RS01905	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7006_RS01915	COG1280	lysine exporter protein (LysE YggA)
D7006_RS01920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7006_RS01935	COG1196	nuclear chromosome segregation
D7006_RS01935	COG3264	Mechanosensitive ion channel
D7006_RS01940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7006_RS01950	COG2951	lytic endotransglycosylase activity
D7006_RS01955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D7006_RS01975	COG0287	Prephenate dehydrogenase
D7006_RS01980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D7006_RS02000	COG2010	Cytochrome c
D7006_RS02015	COG3321	synthase
D7006_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS02015	COG0604	alcohol dehydrogenase
D7006_RS02020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS02045	COG2368	4-hydroxyphenylacetate
D7006_RS02060	COG2205	protein histidine kinase activity
D7006_RS02115	COG0488	(ABC) transporter
D7006_RS02130	COG2391	methyltransferase activity
D7006_RS02135	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7006_RS02145	COG0175	sulfate reduction
D7006_RS02170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7006_RS02175	COG2862	Uncharacterized protein family, UPF0114
D7006_RS02180	COG2610	gluconate transmembrane transporter activity
D7006_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS02210	COG0517	IMP dehydrogenase activity
D7006_RS02210	COG1994	Peptidase M50
D7006_RS02220	COG2814	Major facilitator Superfamily
D7006_RS02230	COG2885	chlorophyll binding
D7006_RS02245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7006_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS02265	COG0129	dihydroxy-acid dehydratase activity
D7006_RS02275	COG1122	ATPase activity
D7006_RS02280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D7006_RS02285	COG1268	BioY protein
D7006_RS02290	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS02335	COG0644	oxidoreductase
D7006_RS02345	COG0137	argininosuccinate synthase activity
D7006_RS02365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D7006_RS02370	COG0167	dihydroorotate dehydrogenase activity
D7006_RS02380	COG1970	mechanosensitive ion channel activity
D7006_RS02385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7006_RS02395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D7006_RS02410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D7006_RS02415	COG0521	Mo-molybdopterin cofactor biosynthetic process
D7006_RS02450	COG0683	leucine binding
D7006_RS02475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS02480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7006_RS02505	COG1764	response to oxidative stress
D7006_RS02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS02525	COG4251	negative regulation of phosphorylation
D7006_RS02530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D7006_RS02555	COG1032	radical SAM domain protein
D7006_RS02565	COG3300	MHYT domain
D7006_RS02565	COG5001	Diguanylate cyclase
D7006_RS02575	COG0242	peptide deformylase activity
D7006_RS02590	COG2824	Alkylphosphonate utilization operon protein PhnA
D7006_RS02595	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS02615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7006_RS02620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7006_RS02625	COG2135	peptidase activity
D7006_RS02635	COG0546	phosphoglycolate phosphatase activity
D7006_RS02645	COG1376	ErfK ybiS ycfS ynhG family protein
D7006_RS02645	COG1388	LysM domain
D7006_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS02665	COG0259	pyridoxamine-phosphate oxidase activity
D7006_RS02675	COG0484	heat shock protein binding
D7006_RS02680	COG2030	dehydratase
D7006_RS02695	COG1733	regulation of RNA biosynthetic process
D7006_RS02700	COG0604	alcohol dehydrogenase
D7006_RS02720	COG0730	response to heat
D7006_RS02725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D7006_RS02735	COG3237	CsbD-like
D7006_RS02740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D7006_RS02745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D7006_RS02750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D7006_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS02775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7006_RS02785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS02790	COG1116	anion transmembrane transporter activity
D7006_RS02795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS02800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS02805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7006_RS02810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS02845	COG0583	DNA-binding transcription factor activity
D7006_RS02850	COG1942	4-Oxalocrotonate Tautomerase
D7006_RS02865	COG1116	anion transmembrane transporter activity
D7006_RS02870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D7006_RS02875	COG0300	oxidoreductase activity
D7006_RS02885	COG1335	isochorismatase
D7006_RS02905	COG1414	Transcriptional regulator
D7006_RS02980	COG0582	viral genome integration into host DNA
D7006_RS03000	COG0513	Belongs to the DEAD box helicase family
D7006_RS03035	COG1475	DNA binding
D7006_RS03070	COG5489	Protein of unknown function (DUF736)
D7006_RS03105	COG1192	Involved in chromosome partitioning
D7006_RS03130	COG0741	lytic transglycosylase activity
D7006_RS03150	COG4962	Type ii secretion system protein e
D7006_RS03165	COG3451	type IV secretory pathway VirB4
D7006_RS03180	COG3846	protein secretion by the type IV secretion system
D7006_RS03195	COG2948	multi-organism process
D7006_RS03215	COG0640	Transcriptional regulator
D7006_RS03255	COG0519	Catalyzes the synthesis of GMP from XMP
D7006_RS03255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7006_RS03305	COG1309	transcriptional regulator
D7006_RS03315	COG1131	(ABC) transporter
D7006_RS03320	COG0842	Transport permease protein
D7006_RS03325	COG3278	Belongs to the heme-copper respiratory oxidase family
D7006_RS03340	COG2010	Cytochrome c
D7006_RS03355	COG2217	Heavy metal translocating P-type atpase
D7006_RS03370	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS03375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D7006_RS03380	COG2967	ApaG domain
D7006_RS03390	COG0717	Belongs to the dCTP deaminase family
D7006_RS03400	COG0625	glutathione transferase activity
D7006_RS03405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7006_RS03420	COG0247	lactate metabolic process
D7006_RS03425	COG0785	Cytochrome C biogenesis protein
D7006_RS03430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7006_RS03435	COG0424	maF-like protein
D7006_RS03440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D7006_RS03445	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS03450	COG0500	methyltransferase
D7006_RS03465	COG0625	glutathione transferase activity
D7006_RS03470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D7006_RS03495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D7006_RS03515	COG0436	Aminotransferase
D7006_RS03520	COG0625	glutathione transferase activity
D7006_RS03530	COG2133	pyrroloquinoline quinone binding
D7006_RS03555	COG0556	nucleotide-excision repair
D7006_RS03570	COG1618	nucleotide phosphatase activity, acting on free nucleotides
D7006_RS03570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D7006_RS03605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D7006_RS03610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7006_RS03615	COG1522	sequence-specific DNA binding
D7006_RS03620	COG0492	ferredoxin-NADP+ reductase activity
D7006_RS03640	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D7006_RS03670	COG1921	L-seryl-tRNASec selenium transferase activity
D7006_RS03680	COG2864	formate dehydrogenase
D7006_RS03685	COG0437	4 iron, 4 sulfur cluster binding
D7006_RS03695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7006_RS03700	COG1305	Transglutaminase-like
D7006_RS03705	COG0709	Synthesizes selenophosphate from selenide and ATP
D7006_RS03720	COG1063	alcohol dehydrogenase
D7006_RS03740	COG2814	Major facilitator Superfamily
D7006_RS03750	COG2814	Major facilitator Superfamily
D7006_RS03755	COG0786	glutamate:sodium symporter activity
D7006_RS03775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D7006_RS03785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D7006_RS03800	COG0604	alcohol dehydrogenase
D7006_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS03800	COG3321	synthase
D7006_RS03815	COG0254	rRNA binding
D7006_RS03820	COG1132	(ABC) transporter
D7006_RS03830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7006_RS03830	COG2169	Transcriptional regulator
D7006_RS03855	COG2358	TRAP transporter, solute receptor (TAXI family
D7006_RS03865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7006_RS03870	COG0288	reversible hydration of carbon dioxide
D7006_RS03885	COG2181	nitrate reductase activity
D7006_RS03890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D7006_RS03895	COG1140	nitrate reductase beta subunit
D7006_RS03900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D7006_RS03905	COG2223	nitrite transmembrane transporter activity
D7006_RS03920	COG2271	Major facilitator Superfamily
D7006_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS03950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
D7006_RS03980	COG2351	hydroxyisourate hydrolase activity
D7006_RS03990	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7006_RS03995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D7006_RS04000	COG3842	ATPase activity
D7006_RS04015	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D7006_RS04025	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS04025	COG1024	Enoyl-CoA hydratase
D7006_RS04030	COG0183	Belongs to the thiolase family
D7006_RS04035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D7006_RS04045	COG1309	transcriptional regulator
D7006_RS04060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS04065	COG0633	Ferredoxin
D7006_RS04095	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS04130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D7006_RS04145	COG2373	Large extracellular alpha-helical protein
D7006_RS04150	COG4953	penicillin-binding protein 1C
D7006_RS04170	COG0596	Alpha beta hydrolase
D7006_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS04190	COG4829	muconolactone delta-isomerase
D7006_RS04200	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS04205	COG1414	Transcriptional regulator
D7006_RS04215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS04240	COG0247	lactate metabolic process
D7006_RS04240	COG2181	nitrate reductase activity
D7006_RS04270	COG1217	gtp-binding protein TYPA
D7006_RS04275	COG0579	oxidoreductase
D7006_RS04285	COG1053	succinate dehydrogenase
D7006_RS04300	COG0366	Alpha amylase catalytic
D7006_RS04305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS04335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D7006_RS04340	COG0778	Nitroreductase
D7006_RS04350	COG4221	oxidoreductase activity
D7006_RS04360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D7006_RS04380	COG0483	inositol monophosphate 1-phosphatase activity
D7006_RS04395	COG0071	Belongs to the small heat shock protein (HSP20) family
D7006_RS04400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7006_RS04440	COG2226	methyltransferase
D7006_RS04455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D7006_RS04460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D7006_RS04465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7006_RS04470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D7006_RS04490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D7006_RS04500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D7006_RS04510	COG0745	RESPONSE REGULATOR receiver
D7006_RS04515	COG0642	Histidine kinase
D7006_RS04525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7006_RS04525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D7006_RS04535	COG3852	Histidine kinase
D7006_RS04550	COG2132	Multicopper oxidase
D7006_RS04570	COG2205	protein histidine kinase activity
D7006_RS04585	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS04595	COG2271	Major facilitator Superfamily
D7006_RS04600	COG4948	Mandelate Racemase Muconate Lactonizing
D7006_RS04620	COG1278	Cold shock
D7006_RS04640	COG3459	Glycosyltransferase 36 associated
D7006_RS04660	COG0753	catalase activity
D7006_RS04680	COG4191	Histidine kinase
D7006_RS04680	COG0784	Response regulator, receiver
D7006_RS04705	COG1850	ribulose-bisphosphate carboxylase activity
D7006_RS04730	COG0523	cobalamin synthesis protein
D7006_RS04740	COG1802	Transcriptional regulator
D7006_RS04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS04810	COG2375	cellular response to nickel ion
D7006_RS04830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS04835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS04850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D7006_RS04860	COG1063	alcohol dehydrogenase
D7006_RS04875	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D7006_RS04880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7006_RS04895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS04900	COG2188	Transcriptional regulator
D7006_RS04920	COG2009	succinate dehydrogenase
D7006_RS04935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D7006_RS04965	COG0028	Belongs to the TPP enzyme family
D7006_RS04970	COG0477	Major facilitator Superfamily
D7006_RS04980	COG1414	Transcriptional regulator
D7006_RS04995	COG1271	oxidase subunit
D7006_RS05000	COG0243	molybdopterin cofactor binding
D7006_RS05005	COG1566	PFAM secretion protein HlyD family protein
D7006_RS05015	COG1289	transmembrane transporter activity
D7006_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS05030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7006_RS05030	COG2010	Cytochrome c
D7006_RS05035	COG2080	2 iron, 2 sulfur cluster binding
D7006_RS05040	COG2010	Cytochrome c
D7006_RS05040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7006_RS05050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7006_RS05050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7006_RS05055	COG2814	Major facilitator Superfamily
D7006_RS05070	COG0025	NhaP-type Na H and K H
D7006_RS05080	COG0783	Belongs to the Dps family
D7006_RS05085	COG4566	intracellular signal transduction
D7006_RS05090	COG4566	intracellular signal transduction
D7006_RS05095	COG4191	Histidine kinase
D7006_RS05115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7006_RS05155	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS05175	COG2140	Oxalate decarboxylase
D7006_RS05180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D7006_RS05220	COG0145	ligase activity
D7006_RS05225	COG4647	ligase activity
D7006_RS05230	COG0145	ligase activity
D7006_RS05235	COG3284	Transcriptional regulator
D7006_RS05240	COG0523	cobalamin synthesis protein
D7006_RS05295	COG1192	Involved in chromosome partitioning
D7006_RS05325	COG1476	TRANSCRIPTIONal
D7006_RS05330	COG1910	domain protein
D7006_RS05340	COG5489	Protein of unknown function (DUF736)
D7006_RS05370	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS05385	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS05410	COG1475	DNA binding
D7006_RS05490	COG5489	Protein of unknown function (DUF736)
D7006_RS05495	COG1476	TRANSCRIPTIONal
D7006_RS05525	COG1192	Involved in chromosome partitioning
D7006_RS05600	COG1960	acyl-CoA dehydrogenase activity
D7006_RS05605	COG1960	acyl-CoA dehydrogenase activity
D7006_RS05610	COG0183	Belongs to the thiolase family
D7006_RS05615	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS05620	COG1024	Enoyl-CoA hydratase
D7006_RS05620	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS05655	COG1024	Enoyl-CoA hydratase
D7006_RS05665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS05680	COG4962	Type ii secretion system protein e
D7006_RS05695	COG3451	type IV secretory pathway VirB4
D7006_RS05725	COG2948	multi-organism process
D7006_RS05785	COG0488	(ABC) transporter
D7006_RS05820	COG2205	protein histidine kinase activity
D7006_RS05830	COG2166	iron-sulfur cluster assembly
D7006_RS05865	COG0151	Belongs to the GarS family
D7006_RS05870	COG1570	exodeoxyribonuclease VII activity
D7006_RS05880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D7006_RS05890	COG2818	Glycosylase
D7006_RS05920	COG0277	FAD linked oxidase domain protein
D7006_RS05935	COG2264	protein methyltransferase activity
D7006_RS05940	COG3706	GGDEF domain
D7006_RS05945	COG0210	DNA helicase
D7006_RS05970	COG0628	permease
D7006_RS05975	COG2902	Dehydrogenase
D7006_RS06015	COG3135	benzoate transporter
D7006_RS06025	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D7006_RS06060	COG0248	Ppx GppA phosphatase
D7006_RS06065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D7006_RS06075	COG0628	permease
D7006_RS06085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D7006_RS06095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7006_RS06100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7006_RS06105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D7006_RS06110	COG1561	YicC-like family, N-terminal region
D7006_RS06115	COG0194	GDP metabolic process
D7006_RS06120	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D7006_RS06125	COG3300	MHYT domain
D7006_RS06125	COG5001	Diguanylate cyclase
D7006_RS06130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D7006_RS06145	COG0280	phosphate acetyltransferase
D7006_RS06145	COG0281	malic enzyme
D7006_RS06150	COG3161	chorismate lyase activity
D7006_RS06185	COG4695	Portal protein
D7006_RS06210	COG0741	lytic transglycosylase activity
D7006_RS06215	COG5640	endopeptidase activity
D7006_RS06340	COG2095	MarC family integral membrane protein
D7006_RS06350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7006_RS06365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS06375	COG1960	acyl-CoA dehydrogenase activity
D7006_RS06380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS06385	COG0346	lactoylglutathione lyase activity
D7006_RS06395	COG0602	queuosine metabolic process
D7006_RS06400	COG0720	synthase
D7006_RS06405	COG0431	NADPH-dependent FMN reductase
D7006_RS06425	COG2132	Multicopper oxidase
D7006_RS06435	COG0672	)-iron permease
D7006_RS06445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D7006_RS06450	COG4149	molybdate abc transporter
D7006_RS06455	COG0725	ABC transporter, periplasmic molybdate-binding protein
D7006_RS06460	COG0586	Pfam SNARE associated Golgi protein
D7006_RS06465	COG0513	Belongs to the DEAD box helicase family
D7006_RS06470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D7006_RS06475	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D7006_RS06480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7006_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS06490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7006_RS06505	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS06530	COG2186	Transcriptional regulator
D7006_RS06545	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
D7006_RS06550	COG3454	Phosphonate metabolism
D7006_RS06555	COG4778	phosphonate C-P lyase system protein PhnL
D7006_RS06560	COG4107	phosphonate C-P lyase system protein PhnK
D7006_RS06565	COG3627	carbon phosphorus lyase activity
D7006_RS06570	COG3626	phosphonate metabolism
D7006_RS06575	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
D7006_RS06580	COG3624	Phosphonate C-P lyase system protein PhnG
D7006_RS06585	COG2188	Transcriptional regulator
D7006_RS06610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D7006_RS06615	COG0154	amidase activity
D7006_RS06620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D7006_RS06625	COG1760	l-serine dehydratase
D7006_RS06635	COG3979	chitinase
D7006_RS06645	COG2072	flavoprotein involved in K transport
D7006_RS06660	COG0667	Aldo Keto reductase
D7006_RS06680	COG0601	transmembrane transport
D7006_RS06685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7006_RS06695	COG4608	Belongs to the ABC transporter superfamily
D7006_RS06700	COG0667	Aldo Keto reductase
D7006_RS06705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS06710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS06730	COG1116	anion transmembrane transporter activity
D7006_RS06735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS06745	COG1464	Belongs to the NlpA lipoprotein family
D7006_RS06765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS06770	COG3685	Protein conserved in bacteria
D7006_RS06775	COG1959	2 iron, 2 sulfur cluster binding
D7006_RS06780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7006_RS06795	COG1573	uracil-dna glycosylase
D7006_RS06820	COG2205	protein histidine kinase activity
D7006_RS06820	COG2202	Pas domain
D7006_RS06825	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D7006_RS06835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D7006_RS06855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7006_RS06865	COG0433	COG0433 Predicted ATPase
D7006_RS06895	COG1335	isochorismatase
D7006_RS06910	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7006_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS06950	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS06960	COG1024	Enoyl-CoA hydratase
D7006_RS06970	COG0583	DNA-binding transcription factor activity
D7006_RS06980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7006_RS06995	COG1960	acyl-CoA dehydrogenase activity
D7006_RS07050	COG0583	DNA-binding transcription factor activity
D7006_RS07055	COG2943	transferase activity, transferring hexosyl groups
D7006_RS07060	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
D7006_RS07065	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS07070	COG1024	Enoyl-CoA hydratase
D7006_RS07085	COG2186	Transcriptional regulator
D7006_RS07090	COG0604	alcohol dehydrogenase
D7006_RS07100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D7006_RS07105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7006_RS07145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS07155	COG1116	anion transmembrane transporter activity
D7006_RS07160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS07170	COG0523	cobalamin synthesis protein
D7006_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS07205	COG0673	inositol 2-dehydrogenase activity
D7006_RS07210	COG3842	ATPase activity
D7006_RS07230	COG0129	dihydroxy-acid dehydratase activity
D7006_RS07235	COG3618	amidohydrolase
D7006_RS07240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7006_RS07255	COG1802	Transcriptional regulator
D7006_RS07260	COG3181	Tripartite tricarboxylate transporter family receptor
D7006_RS07265	COG4948	Mandelate Racemase Muconate Lactonizing
D7006_RS07270	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS07275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7006_RS07280	COG4948	Mandelate Racemase Muconate Lactonizing
D7006_RS07300	COG0489	protein tyrosine kinase activity
D7006_RS07305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D7006_RS07315	COG0752	glycyl-tRNA synthetase alpha subunit
D7006_RS07390	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
D7006_RS07395	COG1797	cobyrinic acid a,c-diamide synthase activity
D7006_RS07400	COG1280	lysine exporter protein (LysE YggA)
D7006_RS07420	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7006_RS07425	COG0842	Transport permease protein
D7006_RS07430	COG1131	(ABC) transporter
D7006_RS07450	COG1960	acyl-CoA dehydrogenase activity
D7006_RS07455	COG0009	L-threonylcarbamoyladenylate synthase
D7006_RS07460	COG0456	acetyltransferase
D7006_RS07465	COG0123	including yeast histone deacetylase and acetoin utilization protein
D7006_RS07480	COG4770	biotin carboxylase activity
D7006_RS07485	COG3665	Urea carboxylase-associated protein
D7006_RS07490	COG3665	Urea carboxylase-associated protein
D7006_RS07495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7006_RS07515	COG0628	permease
D7006_RS07525	COG5328	Belongs to the UPF0262 family
D7006_RS07535	COG5001	Diguanylate cyclase
D7006_RS07535	COG3300	MHYT domain
D7006_RS07565	COG1137	ATPase activity
D7006_RS07575	COG0693	protein deglycase activity
D7006_RS07585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D7006_RS07590	COG0358	DNA primase activity
D7006_RS07595	COG2827	Endonuclease containing a URI domain
D7006_RS07600	COG1115	amino acid carrier protein
D7006_RS07610	COG0505	Belongs to the CarA family
D7006_RS07615	COG1802	Transcriptional regulator
D7006_RS07625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS07645	COG0166	Belongs to the GPI family
D7006_RS07650	COG0363	glucosamine-6-phosphate deaminase activity
D7006_RS07655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D7006_RS07660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D7006_RS07670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D7006_RS07680	COG1560	Kdo2-lipid A biosynthetic process
D7006_RS07695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7006_RS07700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7006_RS07705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7006_RS07710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7006_RS07715	COG2321	neutral zinc metallopeptidase
D7006_RS07720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D7006_RS07730	COG1294	oxidase, subunit
D7006_RS07735	COG1271	oxidase subunit
D7006_RS07740	COG2814	Major facilitator Superfamily
D7006_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS07750	COG1477	protein flavinylation
D7006_RS07785	COG0410	ABC transporter
D7006_RS07790	COG0411	ABC transporter
D7006_RS07815	COG1309	transcriptional regulator
D7006_RS07820	COG0154	amidase activity
D7006_RS07825	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D7006_RS07850	COG0583	DNA-binding transcription factor activity
D7006_RS07860	COG0154	amidase activity
D7006_RS07895	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS07905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7006_RS07910	COG1024	Enoyl-CoA hydratase
D7006_RS07935	COG3284	Transcriptional regulator
D7006_RS07940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7006_RS07945	COG0022	dehydrogenase e1 component
D7006_RS07950	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7006_RS07950	COG0596	Alpha beta hydrolase
D7006_RS07960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7006_RS07965	COG1063	alcohol dehydrogenase
D7006_RS07985	COG4774	siderophore transport
D7006_RS08050	COG0582	viral genome integration into host DNA
D7006_RS08065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7006_RS08110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7006_RS08130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D7006_RS08150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D7006_RS08160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D7006_RS08165	COG0081	regulation of translation
D7006_RS08170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D7006_RS08175	COG0222	ribosome binding
D7006_RS08180	COG0085	RNA polymerase activity
D7006_RS08185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D7006_RS08190	COG0531	amino acid
D7006_RS08205	COG1032	radical SAM domain protein
D7006_RS08210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS08245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7006_RS08250	COG0583	DNA-binding transcription factor activity
D7006_RS08255	COG0477	Major facilitator Superfamily
D7006_RS08260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS08285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS08290	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D7006_RS08290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D7006_RS08295	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS08305	COG0183	Belongs to the thiolase family
D7006_RS08310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D7006_RS08315	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
D7006_RS08335	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7006_RS08340	COG3842	ATPase activity
D7006_RS08350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7006_RS08370	COG3842	ATPase activity
D7006_RS08375	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7006_RS08380	COG1177	transmembrane transport
D7006_RS08405	COG0714	Associated with various cellular activities
D7006_RS08415	COG0494	nUDIX hydrolase
D7006_RS08425	COG0617	tRNA 3'-terminal CCA addition
D7006_RS08435	COG0408	coproporphyrinogen oxidase activity
D7006_RS08440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D7006_RS08450	COG0723	plastoquinol--plastocyanin reductase activity
D7006_RS08455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D7006_RS08455	COG2857	Cytochrome c1
D7006_RS08460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D7006_RS08460	COG2857	Cytochrome c1
D7006_RS08465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D7006_RS08470	COG2003	Belongs to the UPF0758 family
D7006_RS08475	COG0024	Methionine aminopeptidase
D7006_RS08480	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D7006_RS08485	COG0483	inositol monophosphate 1-phosphatase activity
D7006_RS08490	COG0823	Involved in the tonB-independent uptake of proteins
D7006_RS08505	COG0811	peptide transport
D7006_RS08510	COG0824	Thioesterase
D7006_RS08525	COG2255	four-way junction helicase activity
D7006_RS08535	COG0632	four-way junction helicase activity
D7006_RS08545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D7006_RS08555	COG0789	Transcriptional regulator
D7006_RS08560	COG0217	transcriptional regulatory protein
D7006_RS08565	COG1692	metallophosphoesterase
D7006_RS08605	COG3588	fructose-bisphosphate aldolase
D7006_RS08610	COG0352	thiamine-phosphate diphosphorylase activity
D7006_RS08620	COG2885	chlorophyll binding
D7006_RS08630	COG0037	tRNA processing
D7006_RS08635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7006_RS08640	COG0728	peptidoglycan biosynthetic process
D7006_RS08645	COG0180	Tryptophanyl-tRNA synthetase
D7006_RS08650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D7006_RS08660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7006_RS08670	COG1040	competence protein
D7006_RS08680	COG1937	Protein conserved in bacteria
D7006_RS08685	COG0742	ribosomal rna small subunit methyltransferase
D7006_RS08695	COG0590	tRNA wobble adenosine to inosine editing
D7006_RS08700	COG0596	Alpha beta hydrolase
D7006_RS08720	COG1489	DNA binding
D7006_RS08745	COG0359	binds to the 23S rRNA
D7006_RS08755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D7006_RS08760	COG0360	Binds together with S18 to 16S ribosomal RNA
D7006_RS08765	COG0726	polysaccharide deacetylase
D7006_RS08770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D7006_RS08785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D7006_RS08795	COG0495	leucyl-tRNA aminoacylation
D7006_RS08815	COG2223	nitrite transmembrane transporter activity
D7006_RS08825	COG0432	Pfam Uncharacterised protein family UPF0047
D7006_RS08830	COG0657	acetylesterase activity
D7006_RS08860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D7006_RS08865	COG0228	four-way junction DNA binding
D7006_RS08875	COG0596	Alpha beta hydrolase
D7006_RS08885	COG0534	Mate efflux family protein
D7006_RS08905	COG1793	dna ligase
D7006_RS08905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D7006_RS08915	COG1793	dna ligase
D7006_RS08915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D7006_RS08925	COG2814	Major facilitator Superfamily
D7006_RS08935	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D7006_RS08940	COG0494	nUDIX hydrolase
D7006_RS08955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS08965	COG1663	tetraacyldisaccharide 4'-kinase activity
D7006_RS08970	COG1519	Transferase
D7006_RS08985	COG0483	inositol monophosphate 1-phosphatase activity
D7006_RS08990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D7006_RS09000	COG4106	trans-aconitate 2-methyltransferase activity
D7006_RS09005	COG0028	Belongs to the TPP enzyme family
D7006_RS09015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D7006_RS09045	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS09065	COG1022	Amp-dependent synthetase and ligase
D7006_RS09070	COG0183	Belongs to the thiolase family
D7006_RS09075	COG1024	Enoyl-CoA hydratase
D7006_RS09075	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS09100	COG0444	Belongs to the ABC transporter superfamily
D7006_RS09105	COG0154	amidase activity
D7006_RS09115	COG4608	Belongs to the ABC transporter superfamily
D7006_RS09120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7006_RS09125	COG0601	transmembrane transport
D7006_RS09130	COG4166	transmembrane transport
D7006_RS09145	COG0625	glutathione transferase activity
D7006_RS09180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7006_RS09185	COG1230	cation diffusion facilitator family transporter
D7006_RS09195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D7006_RS09200	COG3383	formate dehydrogenase (NAD+) activity
D7006_RS09215	COG0583	DNA-binding transcription factor activity
D7006_RS09245	COG1218	3'(2'),5'-bisphosphate nucleotidase
D7006_RS09265	COG0745	RESPONSE REGULATOR receiver
D7006_RS09285	COG3706	GGDEF domain
D7006_RS09290	COG0010	Belongs to the arginase family
D7006_RS09295	COG0387	Pfam Sodium calcium exchanger
D7006_RS09310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D7006_RS09315	COG0436	Aminotransferase
D7006_RS09330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D7006_RS09335	COG0511	ligase activity, forming carbon-carbon bonds
D7006_RS09345	COG0800	Aldolase
D7006_RS09350	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS09365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D7006_RS09375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D7006_RS09385	COG2423	ornithine cyclodeaminase activity
D7006_RS09390	COG0386	Belongs to the glutathione peroxidase family
D7006_RS09400	COG0145	ligase activity
D7006_RS09405	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
D7006_RS09410	COG4647	ligase activity
D7006_RS09425	COG2267	carboxylic ester hydrolase activity
D7006_RS09440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D7006_RS09455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D7006_RS09460	COG0560	Phosphoserine phosphatase
D7006_RS09470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D7006_RS09475	COG3045	CreA protein
D7006_RS09490	COG0215	cysteine-tRNA ligase activity
D7006_RS09500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7006_RS09505	COG2259	Doxx family
D7006_RS09510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS09520	COG1309	transcriptional regulator
D7006_RS09535	COG0523	cobalamin synthesis protein
D7006_RS09540	COG0803	Belongs to the bacterial solute-binding protein 9 family
D7006_RS09580	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7006_RS09580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS09590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS09605	COG2885	chlorophyll binding
D7006_RS09625	COG0069	glutamate synthase activity
D7006_RS09630	COG2218	PFAM glutamate synthase alpha subunit domain protein
D7006_RS09635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D7006_RS09650	COG1032	radical SAM domain protein
D7006_RS09660	COG0400	carboxylic ester hydrolase activity
D7006_RS09665	COG0346	lactoylglutathione lyase activity
D7006_RS09685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS09690	COG1116	anion transmembrane transporter activity
D7006_RS09695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS09720	COG4149	molybdate abc transporter
D7006_RS09725	COG1840	ABC-type Fe3 transport system, periplasmic component
D7006_RS09760	COG0859	PFAM glycosyl transferase family 9
D7006_RS09780	COG1492	cobalamin metabolic process
D7006_RS09810	COG3768	UPF0283 membrane protein
D7006_RS09815	COG0785	Cytochrome C biogenesis protein
D7006_RS09820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D7006_RS09825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D7006_RS09865	COG1254	Belongs to the acylphosphatase family
D7006_RS09880	COG0625	glutathione transferase activity
D7006_RS09910	COG0697	spore germination
D7006_RS09925	COG2885	chlorophyll binding
D7006_RS09925	COG3047	cAMP biosynthetic process
D7006_RS09940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7006_RS09945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D7006_RS09960	COG1573	uracil-dna glycosylase
D7006_RS09970	COG1758	RNA polymerase activity
D7006_RS09980	COG0679	Auxin Efflux Carrier
D7006_RS09985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7006_RS09995	COG0400	carboxylic ester hydrolase activity
D7006_RS10005	COG2897	thiosulfate sulfurtransferase activity
D7006_RS10015	COG0415	Belongs to the DNA photolyase family
D7006_RS10020	COG0477	Major facilitator Superfamily
D7006_RS10025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7006_RS10050	COG2202	Pas domain
D7006_RS10050	COG2200	EAL domain
D7006_RS10050	COG2199	diguanylate cyclase activity
D7006_RS10060	COG1530	ribonuclease E activity
D7006_RS10060	COG1530	ribonuclease E activity
D7006_RS10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
D7006_RS10070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS10075	COG1024	Enoyl-CoA hydratase
D7006_RS10080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS10090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D7006_RS10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D7006_RS10150	COG4302	ethanolamine ammonia-lyase activity
D7006_RS10155	COG4303	Ethanolamine ammonia lyase large subunit
D7006_RS10175	COG1116	anion transmembrane transporter activity
D7006_RS10180	COG3634	alkyl hydroperoxide reductase activity
D7006_RS10190	COG0438	transferase activity, transferring glycosyl groups
D7006_RS10195	COG0438	transferase activity, transferring glycosyl groups
D7006_RS10200	COG0156	8-amino-7-oxononanoate synthase activity
D7006_RS10205	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS10205	COG3321	synthase
D7006_RS10205	COG0604	alcohol dehydrogenase
D7006_RS10290	COG0457	Tetratricopeptide repeat
D7006_RS10305	COG0642	Histidine kinase
D7006_RS10310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS10315	COG1116	anion transmembrane transporter activity
D7006_RS10330	COG2202	Pas domain
D7006_RS10330	COG3920	Histidine kinase
D7006_RS10355	COG2197	response regulator
D7006_RS10360	COG0251	oxidation-reduction process
D7006_RS10385	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS10405	COG2188	Transcriptional regulator
D7006_RS10465	COG1136	(ABC) transporter
D7006_RS10475	COG1116	anion transmembrane transporter activity
D7006_RS10490	COG0411	ABC transporter
D7006_RS10510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D7006_RS10515	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS10520	COG1309	transcriptional regulator
D7006_RS10555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D7006_RS10560	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D7006_RS10580	COG3263	regulation of cellular component size
D7006_RS10600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7006_RS10605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D7006_RS10605	COG2755	lipolytic protein G-D-S-L family
D7006_RS10610	COG2755	lipolytic protein G-D-S-L family
D7006_RS10610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D7006_RS10620	COG1960	acyl-CoA dehydrogenase activity
D7006_RS10625	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS10625	COG1024	Enoyl-CoA hydratase
D7006_RS10630	COG0183	Belongs to the thiolase family
D7006_RS10640	COG2067	long-chain fatty acid transport protein
D7006_RS10645	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS10650	COG0052	Belongs to the universal ribosomal protein uS2 family
D7006_RS10655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D7006_RS10660	COG0528	UMP kinase activity
D7006_RS10665	COG0233	cytoplasmic translational termination
D7006_RS10680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D7006_RS10685	COG0750	zinc metalloprotease
D7006_RS10690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7006_RS10695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7006_RS10700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7006_RS10705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7006_RS10710	COG3494	Protein of unknown function (DUF1009)
D7006_RS10715	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7006_RS10720	COG0372	Belongs to the citrate synthase family
D7006_RS10725	COG0746	molybdenum cofactor guanylyltransferase activity
D7006_RS10750	COG2239	Acts as a magnesium transporter
D7006_RS10780	COG5265	(ABC) transporter
D7006_RS10790	COG4941	Belongs to the sigma-70 factor family
D7006_RS10795	COG3795	YCII-related domain
D7006_RS10800	COG1472	Belongs to the glycosyl hydrolase 3 family
D7006_RS10805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D7006_RS10810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D7006_RS10815	COG3842	ATPase activity
D7006_RS10820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7006_RS10825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7006_RS10830	COG0805	protein transport
D7006_RS10835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D7006_RS10840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D7006_RS10845	COG1862	Preprotein translocase
D7006_RS10850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D7006_RS10860	COG3737	Protein of unknown function (DUF498/DUF598)
D7006_RS10870	COG0343	queuine tRNA-ribosyltransferase activity
D7006_RS10875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D7006_RS10880	COG3932	Exopolysaccharide synthesis, ExoD
D7006_RS10885	COG5425	PFAM Usg family protein
D7006_RS10890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D7006_RS10895	COG0459	protein refolding
D7006_RS10905	COG0848	biopolymer transport protein
D7006_RS10915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D7006_RS10920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D7006_RS10925	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7006_RS10925	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7006_RS10935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D7006_RS10940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D7006_RS10945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D7006_RS10975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D7006_RS10980	COG0148	phosphopyruvate hydratase activity
D7006_RS10985	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS10990	COG2095	MarC family integral membrane protein
D7006_RS10995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D7006_RS11015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D7006_RS11055	COG2226	methyltransferase
D7006_RS11075	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
D7006_RS11085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D7006_RS11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7006_RS11100	COG2301	Belongs to the HpcH HpaI aldolase family
D7006_RS11110	COG0679	Auxin Efflux Carrier
D7006_RS11115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS11120	COG0861	Integral membrane protein TerC family
D7006_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS11140	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D7006_RS11145	COG0736	holo-[acyl-carrier-protein] synthase activity
D7006_RS11150	COG0681	Belongs to the peptidase S26 family
D7006_RS11155	COG0571	ribonuclease III activity
D7006_RS11160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D7006_RS11170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7006_RS11175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7006_RS11180	COG3706	GGDEF domain
D7006_RS11185	COG2832	Protein of unknown function (DUF454)
D7006_RS11190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D7006_RS11195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D7006_RS11210	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D7006_RS11215	COG2329	Antibiotic biosynthesis monooxygenase
D7006_RS11225	COG4558	Periplasmic binding protein
D7006_RS11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7006_RS11235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D7006_RS11250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D7006_RS11255	COG2860	membrane
D7006_RS11265	COG2252	PERMEase
D7006_RS11275	COG0504	CTP synthase activity
D7006_RS11320	COG2010	Cytochrome c
D7006_RS11320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7006_RS11325	COG2080	2 iron, 2 sulfur cluster binding
D7006_RS11370	COG1846	Transcriptional regulator
D7006_RS11380	COG3634	alkyl hydroperoxide reductase activity
D7006_RS11385	COG0583	DNA-binding transcription factor activity
D7006_RS11390	COG4191	Histidine kinase
D7006_RS11405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7006_RS11410	COG1609	Transcriptional regulator
D7006_RS11415	COG0765	amino acid transport
D7006_RS11420	COG0765	amino acid transport
D7006_RS11430	COG1126	abc transporter atp-binding protein
D7006_RS11435	COG3734	2-keto-3-deoxy-galactonokinase
D7006_RS11440	COG0800	Aldolase
D7006_RS11445	COG2186	Transcriptional regulator
D7006_RS11465	COG2814	Major facilitator Superfamily
D7006_RS11470	COG4221	oxidoreductase activity
D7006_RS11495	COG4319	ketosteroid isomerase
D7006_RS11530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7006_RS11570	COG1686	Belongs to the peptidase S11 family
D7006_RS11575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D7006_RS11580	COG0470	DNA polymerase III
D7006_RS11595	COG1268	BioY protein
D7006_RS11600	COG0084	hydrolase, TatD family'
D7006_RS11605	COG1832	CoA-binding protein
D7006_RS11615	COG0583	DNA-binding transcription factor activity
D7006_RS11620	COG1380	Effector of murein hydrolase LrgA
D7006_RS11625	COG1346	cytolysis
D7006_RS11630	COG1612	heme a metabolic process
D7006_RS11645	COG1024	Enoyl-CoA hydratase
D7006_RS11655	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D7006_RS11660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D7006_RS11685	COG0628	permease
D7006_RS11700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D7006_RS11710	COG1381	Involved in DNA repair and RecF pathway recombination
D7006_RS11720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7006_RS11730	COG0022	dehydrogenase e1 component
D7006_RS11730	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7006_RS11740	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7006_RS11755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7006_RS11765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7006_RS11770	COG2867	negative regulation of translational initiation
D7006_RS11780	COG0683	leucine binding
D7006_RS11785	COG0683	leucine binding
D7006_RS11835	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D7006_RS11840	COG3548	integral membrane protein
D7006_RS11850	COG1960	acyl-CoA dehydrogenase activity
D7006_RS11860	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D7006_RS11875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D7006_RS11880	COG0629	single-stranded DNA binding
D7006_RS11890	COG1280	lysine exporter protein (LysE YggA)
D7006_RS11895	COG0514	ATP-dependent DNA helicase (RecQ)
D7006_RS11910	COG0730	response to heat
D7006_RS11915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7006_RS11950	COG0656	L-ascorbic acid biosynthetic process
D7006_RS11970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D7006_RS11990	COG0416	fatty acid biosynthetic process
D7006_RS11995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D7006_RS12000	COG0776	regulation of translation
D7006_RS12010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D7006_RS12020	COG0321	lipoyl(octanoyl) transferase activity
D7006_RS12020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D7006_RS12030	COG3956	TIGRFAM MazG family protein
D7006_RS12035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D7006_RS12040	COG1923	regulation of RNA biosynthetic process
D7006_RS12045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D7006_RS12055	COG0569	domain protein
D7006_RS12060	COG2204	response regulator
D7006_RS12065	COG5000	phosphorelay sensor kinase activity
D7006_RS12075	COG2204	response regulator
D7006_RS12090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D7006_RS12090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D7006_RS12095	COG1058	Belongs to the CinA family
D7006_RS12095	COG1546	Belongs to the CinA family
D7006_RS12105	COG0018	arginyl-trna synthetase
D7006_RS12110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D7006_RS12115	COG0316	Belongs to the HesB IscA family
D7006_RS12145	COG0525	valine-tRNA ligase activity
D7006_RS12165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D7006_RS12180	COG0463	Glycosyl transferase, family 2
D7006_RS12180	COG1216	Glycosyl transferase, family 2
D7006_RS12190	COG1132	(ABC) transporter
D7006_RS12245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D7006_RS12275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D7006_RS12295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D7006_RS12300	COG0830	nickel cation binding
D7006_RS12305	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D7006_RS12310	COG0783	Belongs to the Dps family
D7006_RS12315	COG0804	urea catabolic process
D7006_RS12320	COG0831	urea catabolic process
D7006_RS12320	COG0832	Belongs to the urease beta subunit family
D7006_RS12325	COG0829	nickel cation binding
D7006_RS12360	COG2239	Acts as a magnesium transporter
D7006_RS12375	COG0477	Major facilitator Superfamily
D7006_RS12390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D7006_RS12400	COG0406	alpha-ribazole phosphatase activity
D7006_RS12410	COG1253	flavin adenine dinucleotide binding
D7006_RS12415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D7006_RS12435	COG0321	lipoyl(octanoyl) transferase activity
D7006_RS12440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7006_RS12450	COG0154	amidase activity
D7006_RS12455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7006_RS12470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D7006_RS12485	COG0540	Belongs to the ATCase OTCase family
D7006_RS12495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D7006_RS12500	COG0758	DNA mediated transformation
D7006_RS12510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D7006_RS12515	COG0477	Major facilitator Superfamily
D7006_RS12530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7006_RS12535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D7006_RS12535	COG3608	succinylglutamate desuccinylase aspartoacylase
D7006_RS12545	COG1509	lysine 2,3-aminomutase activity
D7006_RS12565	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D7006_RS12570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D7006_RS12575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D7006_RS12590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D7006_RS12600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D7006_RS12605	COG0134	indole-3-glycerol-phosphate synthase activity
D7006_RS12615	COG0315	cyclic pyranopterin monophosphate synthase activity
D7006_RS12620	COG0303	'Molybdopterin
D7006_RS12625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D7006_RS12635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7006_RS12645	COG1473	amidohydrolase
D7006_RS12665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D7006_RS12665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D7006_RS12675	COG0024	Methionine aminopeptidase
D7006_RS12680	COG1304	FMN binding
D7006_RS12690	COG1131	(ABC) transporter
D7006_RS12700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D7006_RS12710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7006_RS12735	COG0633	Ferredoxin
D7006_RS12745	COG3191	aminopeptidase activity
D7006_RS12765	COG3106	COG3106 Predicted ATPase
D7006_RS12780	COG1127	ABC transporter
D7006_RS12785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D7006_RS12790	COG4948	Mandelate Racemase Muconate Lactonizing
D7006_RS12805	COG0438	transferase activity, transferring glycosyl groups
D7006_RS12835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D7006_RS12870	COG1891	lyase activity
D7006_RS12875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7006_RS12880	COG2154	pterin-4-alpha-carbinolamine dehydratase
D7006_RS12895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D7006_RS12905	COG1686	Belongs to the peptidase S11 family
D7006_RS12920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D7006_RS12930	COG0626	cystathionine gamma-synthase activity
D7006_RS12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7006_RS12940	COG4597	amino acid ABC transporter
D7006_RS12945	COG0765	amino acid transport
D7006_RS12950	COG1126	abc transporter atp-binding protein
D7006_RS12960	COG1215	transferase activity, transferring glycosyl groups
D7006_RS12985	COG0351	phosphomethylpyrimidine kinase
D7006_RS12990	COG1396	sequence-specific DNA binding
D7006_RS13025	COG1136	(ABC) transporter
D7006_RS13035	COG0442	prolyl-tRNA aminoacylation
D7006_RS13045	COG2151	metal-sulfur cluster biosynthetic enzyme
D7006_RS13050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7006_RS13055	COG0719	Fe-S assembly protein
D7006_RS13060	COG0396	ATPase activity
D7006_RS13065	COG0719	Fe-S assembly protein
D7006_RS13070	COG1104	cysteine desulfurase activity
D7006_RS13075	COG2945	thiolester hydrolase activity
D7006_RS13080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D7006_RS13085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D7006_RS13090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D7006_RS13100	COG1971	Probably functions as a manganese efflux pump
D7006_RS13105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D7006_RS13115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D7006_RS13120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D7006_RS13130	COG0047	phosphoribosylformylglycinamidine synthase activity
D7006_RS13135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D7006_RS13145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D7006_RS13155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D7006_RS13160	COG5001	Diguanylate cyclase
D7006_RS13160	COG3300	MHYT domain
D7006_RS13180	COG0134	indole-3-glycerol-phosphate synthase activity
D7006_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS13200	COG4122	O-methyltransferase activity
D7006_RS13210	COG1024	Enoyl-CoA hydratase
D7006_RS13215	COG0113	porphobilinogen synthase activity
D7006_RS13220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7006_RS13225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D7006_RS13235	COG0557	exoribonuclease II activity
D7006_RS13255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D7006_RS13265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7006_RS13300	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D7006_RS13305	COG4133	protoheme IX ABC transporter activity
D7006_RS13310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D7006_RS13330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D7006_RS13340	COG0667	Aldo Keto reductase
D7006_RS13345	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D7006_RS13350	COG0110	maltose O-acetyltransferase activity
D7006_RS13360	COG0297	glycogen (starch) synthase activity
D7006_RS13375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D7006_RS13375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D7006_RS13390	COG0297	glycogen (starch) synthase activity
D7006_RS13395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7006_RS13400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D7006_RS13410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D7006_RS13420	COG2942	2-epimerase
D7006_RS13425	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D7006_RS13430	COG1088	dTDP-glucose 4,6-dehydratase activity
D7006_RS13435	COG1091	dTDP-4-dehydrorhamnose reductase activity
D7006_RS13455	COG2963	transposase activity
D7006_RS13460	COG3436	PFAM IS66 Orf2 family protein
D7006_RS13485	COG3206	protein involved in exopolysaccharide biosynthesis
D7006_RS13485	COG0489	protein tyrosine kinase activity
D7006_RS13515	COG1058	Belongs to the CinA family
D7006_RS13515	COG1546	Belongs to the CinA family
D7006_RS13520	COG2308	Evidence 4 Homologs of previously reported genes of
D7006_RS13535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D7006_RS13540	COG0537	adenosine 5'-monophosphoramidase activity
D7006_RS13565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D7006_RS13575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D7006_RS13575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D7006_RS13580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D7006_RS13585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS13590	COG1215	transferase activity, transferring glycosyl groups
D7006_RS13610	COG0776	regulation of translation
D7006_RS13615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D7006_RS13620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D7006_RS13625	COG0740	serine-type endopeptidase activity
D7006_RS13630	COG0544	peptidyl-prolyl cis-trans isomerase activity
D7006_RS13645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D7006_RS13645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D7006_RS13650	COG0347	Belongs to the P(II) protein family
D7006_RS13655	COG0174	glutamine synthetase
D7006_RS13665	COG0538	isocitrate dehydrogenase activity
D7006_RS13670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7006_RS13680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D7006_RS13685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D7006_RS13720	COG0683	leucine binding
D7006_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS13750	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS13770	COG0625	glutathione transferase activity
D7006_RS13775	COG0625	glutathione transferase activity
D7006_RS13810	COG0583	DNA-binding transcription factor activity
D7006_RS13830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7006_RS13855	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
D7006_RS13860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D7006_RS13875	COG1595	DNA-templated transcription, initiation
D7006_RS13890	COG0596	Alpha beta hydrolase
D7006_RS13905	COG0183	Belongs to the thiolase family
D7006_RS13920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7006_RS13945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7006_RS13950	COG0601	transmembrane transport
D7006_RS13955	COG0747	negative chemotaxis
D7006_RS13970	COG2111	Na H antiporter
D7006_RS13970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7006_RS13975	COG1006	Multisubunit Na H antiporter MnhC subunit
D7006_RS13980	COG0651	ATP synthesis coupled electron transport
D7006_RS13990	COG2212	antiporter activity
D7006_RS13995	COG1320	monovalent cation:proton antiporter activity
D7006_RS14005	COG2819	hydrolase of the alpha beta superfamily
D7006_RS14020	COG4607	ABC-type enterochelin transport system periplasmic component
D7006_RS14025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7006_RS14030	COG4605	iron ion homeostasis
D7006_RS14035	COG4604	ABC transporter, ATP-binding protein
D7006_RS14045	COG4774	siderophore transport
D7006_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS14070	COG1535	isochorismatase
D7006_RS14070	COG3433	isochorismatase activity
D7006_RS14075	COG1021	2,3-dihydroxybenzoate-AMP ligase
D7006_RS14080	COG1169	isochorismate synthase
D7006_RS14085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7006_RS14095	COG1535	isochorismatase
D7006_RS14095	COG3433	isochorismatase activity
D7006_RS14100	COG0577	efflux transmembrane transporter activity
D7006_RS14100	COG1136	(ABC) transporter
D7006_RS14105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS14190	COG1802	Transcriptional regulator
D7006_RS14215	COG3971	2-oxopent-4-enoate hydratase activity
D7006_RS14220	COG4569	acetaldehyde dehydrogenase (acetylating) activity
D7006_RS14225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7006_RS14235	COG1942	4-Oxalocrotonate Tautomerase
D7006_RS14455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D7006_RS14455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D7006_RS14500	COG3617	BRO family, N-terminal domain
D7006_RS14550	COG0316	Belongs to the HesB IscA family
D7006_RS14555	COG5001	Diguanylate cyclase
D7006_RS14565	COG0346	lactoylglutathione lyase activity
D7006_RS14580	COG1007	ATP synthesis coupled electron transport
D7006_RS14595	COG0713	ATP synthesis coupled electron transport
D7006_RS14605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7006_RS14610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D7006_RS14620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D7006_RS14630	COG0649	NAD binding
D7006_RS14635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7006_RS14640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7006_RS14670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7006_RS14680	COG0640	Transcriptional regulator
D7006_RS14695	COG3346	SURF1 family
D7006_RS14710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D7006_RS14720	COG0109	protoheme IX farnesyltransferase activity
D7006_RS14725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D7006_RS14730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D7006_RS14730	COG1565	acr, cog1565
D7006_RS14740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7006_RS14740	COG0475	glutathione-regulated potassium exporter activity
D7006_RS14755	COG0583	DNA-binding transcription factor activity
D7006_RS14760	COG1802	Transcriptional regulator
D7006_RS14785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7006_RS14790	COG0601	transmembrane transport
D7006_RS14805	COG0688	phosphatidylethanolamine metabolic process
D7006_RS14810	COG2207	Transcriptional regulator
D7006_RS14820	COG0183	Belongs to the thiolase family
D7006_RS14825	COG1960	acyl-CoA dehydrogenase activity
D7006_RS14830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS14870	COG0411	ABC transporter
D7006_RS14875	COG1137	ATPase activity
D7006_RS14895	COG1393	Belongs to the ArsC family
D7006_RS14920	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS14945	COG1309	transcriptional regulator
D7006_RS14965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D7006_RS14970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D7006_RS14985	COG0612	Peptidase, M16
D7006_RS14995	COG3243	poly(R)-hydroxyalkanoic acid synthase
D7006_RS15005	COG0436	Aminotransferase
D7006_RS15015	COG1494	fructose-1,6-bisphosphatase
D7006_RS15020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D7006_RS15030	COG0640	Transcriptional regulator
D7006_RS15035	COG2610	gluconate transmembrane transporter activity
D7006_RS15040	COG2610	gluconate transmembrane transporter activity
D7006_RS15045	COG1192	Involved in chromosome partitioning
D7006_RS15055	COG3619	membrane
D7006_RS15065	COG0187	DNA topoisomerase II activity
D7006_RS15075	COG0583	DNA-binding transcription factor activity
D7006_RS15080	COG0667	Aldo Keto reductase
D7006_RS15085	COG2814	Major facilitator Superfamily
D7006_RS15090	COG0513	Belongs to the DEAD box helicase family
D7006_RS15115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D7006_RS15135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D7006_RS15140	COG3668	Plasmid stabilization system
D7006_RS15150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D7006_RS15165	COG0203	ribosomal protein L17
D7006_RS15170	COG0202	RNA polymerase activity
D7006_RS15175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D7006_RS15180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D7006_RS15190	COG0563	adenylate kinase activity
D7006_RS15195	COG0201	protein transport
D7006_RS15200	COG0200	Binds to the 23S rRNA
D7006_RS15205	COG1841	ribosomal large subunit assembly
D7006_RS15210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D7006_RS15215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D7006_RS15220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D7006_RS15225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D7006_RS15230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D7006_RS15235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D7006_RS15240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D7006_RS15245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D7006_RS15250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D7006_RS15255	COG0255	Belongs to the universal ribosomal protein uL29 family
D7006_RS15260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D7006_RS15265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D7006_RS15270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D7006_RS15275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D7006_RS15280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D7006_RS15285	COG0089	rRNA binding
D7006_RS15290	COG0088	Forms part of the polypeptide exit tunnel
D7006_RS15295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D7006_RS15300	COG0051	transcription antitermination factor activity, RNA binding
D7006_RS15305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D7006_RS15310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D7006_RS15315	COG0049	tRNA binding
D7006_RS15320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D7006_RS15325	COG0039	L-malate dehydrogenase activity
D7006_RS15340	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D7006_RS15345	COG1704	LemA family
D7006_RS15355	COG0114	fumarate hydratase activity
D7006_RS15370	COG0330	HflC and HflK could
D7006_RS15375	COG0330	HflC and HflK could
D7006_RS15390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7006_RS15390	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
D7006_RS15400	COG1396	sequence-specific DNA binding
D7006_RS15400	COG3800	Transcriptional regulator
D7006_RS15405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7006_RS15410	COG4770	biotin carboxylase activity
D7006_RS15415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D7006_RS15445	COG0163	prenyltransferase activity
D7006_RS15455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS15470	COG1846	Transcriptional regulator
D7006_RS15480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7006_RS15485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS15495	COG0604	alcohol dehydrogenase
D7006_RS15510	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS15525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D7006_RS15535	COG0859	PFAM glycosyl transferase family 9
D7006_RS15565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D7006_RS15585	COG0308	aminopeptidase N
D7006_RS15590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D7006_RS15600	COG0745	RESPONSE REGULATOR receiver
D7006_RS15605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7006_RS15695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D7006_RS15720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D7006_RS15725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D7006_RS15740	COG0302	gtp cyclohydrolase
D7006_RS15745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D7006_RS15755	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7006_RS15760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7006_RS15780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D7006_RS15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7006_RS15800	COG1376	ErfK ybiS ycfS ynhG family protein
D7006_RS15805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D7006_RS15830	COG0778	Nitroreductase
D7006_RS15835	COG4974	Belongs to the 'phage' integrase family
D7006_RS15850	COG1595	DNA-templated transcription, initiation
D7006_RS15865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D7006_RS15870	COG5265	(ABC) transporter
D7006_RS15880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS15905	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D7006_RS15910	COG2814	Major facilitator Superfamily
D7006_RS15925	COG0438	transferase activity, transferring glycosyl groups
D7006_RS15925	COG1216	Glycosyl transferase, family 2
D7006_RS15935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D7006_RS15945	COG0546	phosphoglycolate phosphatase activity
D7006_RS15960	COG3685	Protein conserved in bacteria
D7006_RS15985	COG1376	ErfK ybiS ycfS ynhG family protein
D7006_RS15990	COG1278	Cold shock
D7006_RS15995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS16000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS16010	COG1674	ftsk spoiiie
D7006_RS16025	COG0587	DNA-directed DNA polymerase activity
D7006_RS16030	COG0726	polysaccharide deacetylase
D7006_RS16035	COG0235	Class ii aldolase
D7006_RS16040	COG2084	Dehydrogenase
D7006_RS16050	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D7006_RS16050	COG2066	Belongs to the glutaminase family
D7006_RS16075	COG2197	response regulator
D7006_RS16090	COG4993	Dehydrogenase
D7006_RS16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7006_RS16110	COG0714	Associated with various cellular activities
D7006_RS16155	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS16160	COG1802	Transcriptional regulator
D7006_RS16170	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7006_RS16200	COG0667	Aldo Keto reductase
D7006_RS16210	COG1024	Enoyl-CoA hydratase
D7006_RS16220	COG0583	DNA-binding transcription factor activity
D7006_RS16250	COG0754	glutathionylspermidine amidase activity
D7006_RS16260	COG1968	undecaprenyl-diphosphatase activity
D7006_RS16265	COG0330	HflC and HflK could
D7006_RS16270	COG0330	HflC and HflK could
D7006_RS16275	COG0861	Integral membrane protein TerC family
D7006_RS16285	COG4139	cobalamin transport
D7006_RS16325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D7006_RS16335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D7006_RS16340	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D7006_RS16345	COG2205	protein histidine kinase activity
D7006_RS16350	COG0745	RESPONSE REGULATOR receiver
D7006_RS16385	COG4944	Protein of unknown function (DUF1109)
D7006_RS16405	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS16415	COG0411	ABC transporter
D7006_RS16430	COG0583	DNA-binding transcription factor activity
D7006_RS16435	COG0154	amidase activity
D7006_RS16450	COG1414	Transcriptional regulator
D7006_RS16470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS16475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS16480	COG1116	anion transmembrane transporter activity
D7006_RS16505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D7006_RS16510	COG2205	protein histidine kinase activity
D7006_RS16510	COG2202	Pas domain
D7006_RS16525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D7006_RS16540	COG1309	transcriptional regulator
D7006_RS16560	COG1309	transcriptional regulator
D7006_RS16565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7006_RS16570	COG2011	ABC-type metal ion transport system permease component
D7006_RS16575	COG1464	Belongs to the NlpA lipoprotein family
D7006_RS16580	COG4106	trans-aconitate 2-methyltransferase activity
D7006_RS16585	COG0174	glutamine synthetase
D7006_RS16615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS16615	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7006_RS16630	COG0714	Associated with various cellular activities
D7006_RS16645	COG2304	oxidoreductase activity
D7006_RS16660	COG0583	DNA-binding transcription factor activity
D7006_RS16675	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7006_RS16685	COG3842	ATPase activity
D7006_RS16715	COG2814	Major facilitator Superfamily
D7006_RS16720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS16725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS16730	COG1116	anion transmembrane transporter activity
D7006_RS16735	COG4191	Histidine kinase
D7006_RS16745	COG3246	L-lysine catabolic process to acetate
D7006_RS16750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7006_RS16760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D7006_RS16825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D7006_RS16840	COG1278	Cold shock
D7006_RS16865	COG2223	nitrite transmembrane transporter activity
D7006_RS16880	COG0583	DNA-binding transcription factor activity
D7006_RS16890	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS16895	COG1802	Transcriptional regulator
D7006_RS16900	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS16915	COG2271	Major facilitator Superfamily
D7006_RS16920	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS16925	COG2271	Major facilitator Superfamily
D7006_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS16960	COG2814	Major facilitator Superfamily
D7006_RS16970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D7006_RS16975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D7006_RS16985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7006_RS16995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS17000	COG2084	Dehydrogenase
D7006_RS17005	COG3958	Transketolase
D7006_RS17010	COG3959	Transketolase, thiamine diphosphate binding domain
D7006_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17020	COG0583	DNA-binding transcription factor activity
D7006_RS17030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS17070	COG1960	acyl-CoA dehydrogenase activity
D7006_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS17085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS17110	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D7006_RS17115	COG3246	L-lysine catabolic process to acetate
D7006_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17140	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS17145	COG3604	Transcriptional regulator
D7006_RS17160	COG0604	alcohol dehydrogenase
D7006_RS17165	COG1960	acyl-CoA dehydrogenase activity
D7006_RS17170	COG1846	Transcriptional regulator
D7006_RS17180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D7006_RS17195	COG1024	Enoyl-CoA hydratase
D7006_RS17195	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS17210	COG2030	dehydratase
D7006_RS17220	COG1902	pentaerythritol trinitrate reductase activity
D7006_RS17225	COG0028	Belongs to the TPP enzyme family
D7006_RS17230	COG0492	ferredoxin-NADP+ reductase activity
D7006_RS17245	COG3971	2-oxopent-4-enoate hydratase activity
D7006_RS17255	COG2814	Major facilitator Superfamily
D7006_RS17260	COG0583	DNA-binding transcription factor activity
D7006_RS17265	COG0477	Major facilitator Superfamily
D7006_RS17275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS17280	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS17285	COG1414	Transcriptional regulator
D7006_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS17335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS17355	COG1393	Belongs to the ArsC family
D7006_RS17360	COG0798	PFAM Bile acid sodium symporter
D7006_RS17365	COG2271	Major facilitator Superfamily
D7006_RS17385	COG1304	FMN binding
D7006_RS17400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS17405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS17420	COG4948	Mandelate Racemase Muconate Lactonizing
D7006_RS17460	COG4974	Belongs to the 'phage' integrase family
D7006_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17510	COG5564	TIM-barrel signal transduction protein
D7006_RS17520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D7006_RS17525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS17535	COG5441	Belongs to the UPF0261 family
D7006_RS17540	COG0583	DNA-binding transcription factor activity
D7006_RS17550	COG2948	multi-organism process
D7006_RS17560	COG3701	Conjugal transfer protein
D7006_RS17580	COG3451	type IV secretory pathway VirB4
D7006_RS17595	COG4962	Type ii secretion system protein e
D7006_RS17615	COG1204	response to ionizing radiation
D7006_RS17670	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D7006_RS17675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D7006_RS17725	COG1192	Involved in chromosome partitioning
D7006_RS17755	COG1476	TRANSCRIPTIONal
D7006_RS17760	COG5489	Protein of unknown function (DUF736)
D7006_RS17785	COG1475	DNA binding
D7006_RS17800	COG4221	oxidoreductase activity
D7006_RS17845	COG1802	Transcriptional regulator
D7006_RS17855	COG0318	PFAM AMP-dependent synthetase and ligase
D7006_RS17860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS17875	COG1305	Transglutaminase-like
D7006_RS17880	COG2307	Protein conserved in bacteria
D7006_RS17880	COG2308	Evidence 4 Homologs of previously reported genes of
D7006_RS17900	COG0653	protein targeting
D7006_RS17915	COG3034	peptidoglycan biosynthetic process
D7006_RS17920	COG0825	malonyl-CoA metabolic process
D7006_RS17935	COG1872	DUF167
D7006_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS17950	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D7006_RS17965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D7006_RS17970	COG2721	sulfolactate sulfo-lyase activity
D7006_RS17980	COG1904	glucuronate isomerase
D7006_RS17985	COG0246	Mannitol dehydrogenase
D7006_RS17995	COG0395	ABC-type sugar transport system, permease component
D7006_RS18010	COG3842	ATPase activity
D7006_RS18015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7006_RS18040	COG0574	Belongs to the PEP-utilizing enzyme family
D7006_RS18040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7006_RS18050	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7006_RS18055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D7006_RS18060	COG0045	succinate-CoA ligase (ADP-forming) activity
D7006_RS18070	COG4191	Histidine kinase
D7006_RS18075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS18085	COG1802	Transcriptional regulator
D7006_RS18110	COG1414	Transcriptional regulator
D7006_RS18115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D7006_RS18120	COG1238	metal cluster binding
D7006_RS18130	COG0067	glutamate synthase
D7006_RS18130	COG0070	glutamate synthase
D7006_RS18130	COG0069	glutamate synthase activity
D7006_RS18140	COG3246	L-lysine catabolic process to acetate
D7006_RS18145	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS18150	COG1129	ABC transporter
D7006_RS18170	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS18205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D7006_RS18210	COG0564	pseudouridine synthase activity
D7006_RS18220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D7006_RS18230	COG1196	nuclear chromosome segregation
D7006_RS18240	COG0356	it plays a direct role in the translocation of protons across the membrane
D7006_RS18250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D7006_RS18255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D7006_RS18285	COG2030	dehydratase
D7006_RS18295	COG3047	cAMP biosynthetic process
D7006_RS18310	COG1053	succinate dehydrogenase
D7006_RS18365	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D7006_RS18370	COG2942	2-epimerase
D7006_RS18380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D7006_RS18415	COG1309	transcriptional regulator
D7006_RS18420	COG1597	lipid kinase activity
D7006_RS18425	COG1253	flavin adenine dinucleotide binding
D7006_RS18435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS18440	COG0174	glutamine synthetase
D7006_RS18450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D7006_RS18465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D7006_RS18470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D7006_RS18475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D7006_RS18480	COG0072	phenylalanine-tRNA ligase activity
D7006_RS18480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7006_RS18485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D7006_RS18490	COG0594	ribonuclease P activity
D7006_RS18495	COG0706	membrane insertase activity
D7006_RS18545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D7006_RS18550	COG4208	sulfate ABC transporter
D7006_RS18565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D7006_RS18570	COG0697	spore germination
D7006_RS18575	COG2835	tetraacyldisaccharide 4'-kinase activity
D7006_RS18580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS18580	COG2022	thiamine diphosphate biosynthetic process
D7006_RS18590	COG2022	thiamine diphosphate biosynthetic process
D7006_RS18595	COG0352	thiamine-phosphate diphosphorylase activity
D7006_RS18610	COG0539	negative regulation of cytoplasmic translation
D7006_RS18645	COG1072	(Pantothenic acid kinase))
D7006_RS18650	COG0140	phosphoribosyl-ATP diphosphatase activity
D7006_RS18655	COG0107	imidazoleglycerol-phosphate synthase activity
D7006_RS18660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D7006_RS18665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D7006_RS18675	COG0131	Imidazoleglycerol-phosphate dehydratase
D7006_RS18680	COG2267	carboxylic ester hydrolase activity
D7006_RS18685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D7006_RS18690	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D7006_RS18695	COG2204	response regulator
D7006_RS18705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D7006_RS18715	COG0006	proline dipeptidase activity
D7006_RS18780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7006_RS18790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D7006_RS18795	COG0384	phenazine biosynthesis protein PhzF
D7006_RS18800	COG1902	pentaerythritol trinitrate reductase activity
D7006_RS18825	COG1024	Enoyl-CoA hydratase
D7006_RS18835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7006_RS18845	COG0175	sulfate reduction
D7006_RS18850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D7006_RS18860	COG4208	sulfate ABC transporter
D7006_RS18865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7006_RS18880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7006_RS18895	COG0183	Belongs to the thiolase family
D7006_RS18905	COG3118	belongs to the thioredoxin family
D7006_RS18905	COG0457	Tetratricopeptide repeat
D7006_RS18910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D7006_RS18915	COG1742	UPF0060 membrane protein
D7006_RS18930	COG1309	transcriptional regulator
D7006_RS18955	COG0142	geranyltranstransferase activity
D7006_RS18995	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
D7006_RS19010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D7006_RS19035	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS19035	COG2030	dehydratase
D7006_RS19040	COG1024	Enoyl-CoA hydratase
D7006_RS19040	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7006_RS19055	COG1024	Enoyl-CoA hydratase
D7006_RS19060	COG2050	protein possibly involved in aromatic compounds catabolism
D7006_RS19075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7006_RS19080	COG2151	metal-sulfur cluster biosynthetic enzyme
D7006_RS19085	COG3396	Phenylacetate-CoA oxygenase
D7006_RS19090	COG3460	Phenylacetate-CoA oxygenase
D7006_RS19095	COG3396	Phenylacetate-CoA oxygenase
D7006_RS19100	COG3327	negative regulation of DNA-templated transcription, initiation
D7006_RS19115	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7006_RS19135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D7006_RS19140	COG4988	ABC transporter
D7006_RS19180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7006_RS19205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS19210	COG1522	sequence-specific DNA binding
D7006_RS19235	COG0366	Alpha amylase catalytic
D7006_RS19245	COG1741	Belongs to the pirin family
D7006_RS19260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D7006_RS19265	COG0791	NLP P60 protein
D7006_RS19270	COG5001	Diguanylate cyclase
D7006_RS19270	COG4251	negative regulation of phosphorylation
D7006_RS19270	COG3706	GGDEF domain
D7006_RS19270	COG2203	Gaf domain
D7006_RS19275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D7006_RS19320	COG0629	single-stranded DNA binding
D7006_RS19590	COG2963	transposase activity
D7006_RS19595	COG3436	PFAM IS66 Orf2 family protein
D7006_RS19675	COG0582	viral genome integration into host DNA
D7006_RS19680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7006_RS19695	COG0596	Alpha beta hydrolase
D7006_RS19700	COG1414	Transcriptional regulator
D7006_RS19710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7006_RS19715	COG0183	Belongs to the thiolase family
D7006_RS19735	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7006_RS19740	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7006_RS19745	COG1129	ABC transporter
D7006_RS19750	COG0277	FAD linked oxidase domain protein
D7006_RS19755	COG3485	protocatechuate 3,4-dioxygenase
D7006_RS19765	COG0402	S-adenosylhomocysteine deaminase activity
D7006_RS19790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7006_RS19795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS19820	COG2186	Transcriptional regulator
D7006_RS19835	COG1024	Enoyl-CoA hydratase
D7006_RS19840	COG5001	Diguanylate cyclase
D7006_RS19840	COG3300	MHYT domain
D7006_RS19855	COG0366	Alpha amylase catalytic
D7006_RS19860	COG0366	Alpha amylase catalytic
D7006_RS19865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D7006_RS19875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D7006_RS19895	COG0431	NADPH-dependent FMN reductase
D7006_RS19925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D7006_RS19945	COG3258	Cytochrome c
D7006_RS19950	COG2010	Cytochrome c
D7006_RS19960	COG0785	Cytochrome C biogenesis protein
D7006_RS19990	COG4232	protein-disulfide reductase activity
D7006_RS20000	COG1388	LysM domain
D7006_RS20000	COG1376	ErfK ybiS ycfS ynhG family protein
D7006_RS20030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS20035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7006_RS20045	COG3527	Alpha-acetolactate decarboxylase
D7006_RS20075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D7006_RS20080	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS20100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS20105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS20110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS20115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7006_RS20135	COG0523	cobalamin synthesis protein
D7006_RS20160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS20165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7006_RS20170	COG1058	Belongs to the CinA family
D7006_RS20170	COG1546	Belongs to the CinA family
D7006_RS20175	COG0523	cobalamin synthesis protein
D7006_RS20190	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS20195	COG0402	S-adenosylhomocysteine deaminase activity
D7006_RS20210	COG0683	leucine binding
D7006_RS20250	COG0129	dihydroxy-acid dehydratase activity
D7006_RS20260	COG1609	Transcriptional regulator
D7006_RS20265	COG2814	Major facilitator Superfamily
D7006_RS20275	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D7006_RS20290	COG1335	isochorismatase
D7006_RS20365	COG0395	ABC-type sugar transport system, permease component
D7006_RS20370	COG1175	transmembrane transport
D7006_RS20380	COG3842	ATPase activity
D7006_RS20390	COG0277	FAD linked oxidase domain protein
D7006_RS20395	COG1609	Transcriptional regulator
D7006_RS20420	COG0784	Response regulator, receiver
D7006_RS20420	COG4191	Histidine kinase
D7006_RS20425	COG2205	protein histidine kinase activity
D7006_RS20430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7006_RS20445	COG2171	N-acyltransferase activity
D7006_RS20460	COG2378	regulation of single-species biofilm formation
D7006_RS20480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D7006_RS20495	COG0494	nUDIX hydrolase
D7006_RS20500	COG4172	Belongs to the ABC transporter superfamily
D7006_RS20515	COG4239	(ABC) transporter, permease
D7006_RS20520	COG4174	ABC transporter (Permease)
D7006_RS20525	COG4166	transmembrane transport
D7006_RS20530	COG4166	transmembrane transport
D7006_RS20535	COG3474	cytochrome
D7006_RS20540	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D7006_RS20555	COG2816	NAD+ diphosphatase activity
D7006_RS20565	COG0527	aspartate kinase activity
D7006_RS20575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D7006_RS20580	COG2890	protein-(glutamine-N5) methyltransferase activity
D7006_RS20590	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
D7006_RS20595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS20595	COG1116	anion transmembrane transporter activity
D7006_RS20600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS20605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS20605	COG1116	anion transmembrane transporter activity
D7006_RS20620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D7006_RS20635	COG1309	transcriptional regulator
D7006_RS20640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D7006_RS20650	COG3258	Cytochrome c
D7006_RS20655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D7006_RS20660	COG0193	aminoacyl-tRNA hydrolase activity
D7006_RS20665	COG0012	GTP binding
D7006_RS20685	COG2030	dehydratase
D7006_RS20695	COG0488	(ABC) transporter
D7006_RS20710	COG0678	peroxiredoxin activity
D7006_RS20720	COG1678	Uncharacterized ACR, COG1678
D7006_RS20725	COG3773	Cell wall hydrolase
D7006_RS20725	COG3409	Peptidoglycan-binding domain 1 protein
D7006_RS20730	COG1703	isobutyryl-CoA mutase activity
D7006_RS20745	COG0473	3-isopropylmalate dehydrogenase activity
D7006_RS20760	COG0494	nUDIX hydrolase
D7006_RS20765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D7006_RS20775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7006_RS20785	COG3842	ATPase activity
D7006_RS20790	COG1177	transmembrane transport
D7006_RS20795	COG4149	molybdate abc transporter
D7006_RS20810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7006_RS20815	COG2368	4-hydroxyphenylacetate
D7006_RS20820	COG0583	DNA-binding transcription factor activity
D7006_RS20830	COG3795	YCII-related domain
D7006_RS20835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7006_RS20860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS20865	COG0728	peptidoglycan biosynthetic process
D7006_RS20870	COG0328	RNA-DNA hybrid ribonuclease activity
D7006_RS20875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D7006_RS20880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D7006_RS20890	COG0589	response to stress
D7006_RS20915	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS20920	COG0314	molybdopterin synthase activity
D7006_RS20930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D7006_RS20935	COG0322	excinuclease ABC activity
D7006_RS20940	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7006_RS20945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7006_RS20950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D7006_RS20955	COG0673	inositol 2-dehydrogenase activity
D7006_RS20975	COG2205	protein histidine kinase activity
D7006_RS20980	COG0745	RESPONSE REGULATOR receiver
D7006_RS20990	COG3411	Ferredoxin
D7006_RS20995	COG4150	thiosulfate binding
D7006_RS21000	COG0667	Aldo Keto reductase
D7006_RS21010	COG0105	UTP biosynthetic process
D7006_RS21015	COG0861	Integral membrane protein TerC family
D7006_RS21020	COG0861	Integral membrane protein TerC family
D7006_RS21025	COG0243	molybdopterin cofactor binding
D7006_RS21030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D7006_RS21035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D7006_RS21040	COG0583	DNA-binding transcription factor activity
D7006_RS21045	COG0753	catalase activity
D7006_RS21050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D7006_RS21100	COG0552	protein localization to endoplasmic reticulum
D7006_RS21105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D7006_RS21110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D7006_RS21155	COG4235	cytochrome complex assembly
D7006_RS21160	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
D7006_RS21165	COG1138	Cytochrome C-type biogenesis protein
D7006_RS21170	COG3088	subunit of a heme lyase
D7006_RS21175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D7006_RS21195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D7006_RS21215	COG1960	acyl-CoA dehydrogenase activity
D7006_RS21225	COG3152	Membrane
D7006_RS21230	COG2267	carboxylic ester hydrolase activity
D7006_RS21240	COG2226	methyltransferase
D7006_RS21245	COG0482	sulfurtransferase activity
D7006_RS21250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D7006_RS21260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D7006_RS21265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D7006_RS21270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7006_RS21280	COG0583	DNA-binding transcription factor activity
D7006_RS21285	COG2233	PERMEase
D7006_RS21290	COG2351	hydroxyisourate hydrolase activity
D7006_RS21295	COG3195	allantoin biosynthetic process
D7006_RS21295	COG3648	Uricase
D7006_RS21310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D7006_RS21315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7006_RS21330	COG4651	solute:proton antiporter activity
D7006_RS21330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7006_RS21340	COG1121	(ABC) transporter
D7006_RS21345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7006_RS21350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7006_RS21365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7006_RS21390	COG1376	ErfK ybiS ycfS ynhG family protein
D7006_RS21395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D7006_RS21400	COG5002	protein histidine kinase activity
D7006_RS21400	COG2205	protein histidine kinase activity
D7006_RS21400	COG0784	Response regulator, receiver
D7006_RS21410	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D7006_RS21420	COG2514	catechol 2,3-dioxygenase activity
D7006_RS21430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D7006_RS21430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D7006_RS21445	COG0604	alcohol dehydrogenase
D7006_RS21450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D7006_RS21455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D7006_RS21465	COG1201	RNA secondary structure unwinding
D7006_RS21475	COG3038	cytochrome b561
D7006_RS21480	COG0066	3-isopropylmalate dehydratase activity
D7006_RS21500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D7006_RS21505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D7006_RS21520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D7006_RS21525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D7006_RS21540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS21555	COG2983	Belongs to the UPF0260 family
D7006_RS21570	COG3706	GGDEF domain
D7006_RS21595	COG0305	Participates in initiation and elongation during chromosome replication
D7006_RS21600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D7006_RS21615	COG1286	toxin biosynthetic process
D7006_RS21620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D7006_RS21630	COG0300	oxidoreductase activity
D7006_RS21640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7006_RS21645	COG0509	glycine decarboxylation via glycine cleavage system
D7006_RS21655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D7006_RS21660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D7006_RS21665	COG0494	nUDIX hydrolase
D7006_RS21675	COG1999	signal sequence binding
D7006_RS21705	COG0776	regulation of translation
D7006_RS21710	COG0616	signal peptide processing
D7006_RS21715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D7006_RS21720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D7006_RS21725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D7006_RS21730	COG1420	regulation of RNA biosynthetic process
D7006_RS21735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D7006_RS21745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D7006_RS21750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D7006_RS21755	COG1366	Belongs to the anti-sigma-factor antagonist family
D7006_RS21760	COG1283	sodium-dependent phosphate transmembrane transporter activity
D7006_RS21805	COG2208	phosphoserine phosphatase activity
D7006_RS21805	COG2770	Histidine kinase
D7006_RS21815	COG0277	FAD linked oxidase domain protein
D7006_RS21820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D7006_RS21830	COG0335	large ribosomal subunit rRNA binding
D7006_RS21840	COG2201	protein-glutamate methylesterase activity
D7006_RS21845	COG1116	anion transmembrane transporter activity
D7006_RS21845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS21850	COG1160	GTP binding
D7006_RS21865	COG3279	Response regulator of the LytR AlgR family
D7006_RS21875	COG1671	Belongs to the UPF0178 family
D7006_RS21905	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D7006_RS21915	COG1496	oxidoreductase activity
D7006_RS21930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7006_RS21940	COG0671	phosphoesterase, PA-phosphatase related
D7006_RS21950	COG1846	Transcriptional regulator
D7006_RS21955	COG0745	RESPONSE REGULATOR receiver
D7006_RS21965	COG0617	tRNA 3'-terminal CCA addition
D7006_RS21970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7006_RS22000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7006_RS22005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7006_RS22010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7006_RS22030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D7006_RS22030	COG0517	IMP dehydrogenase activity
D7006_RS22035	COG0450	alkyl hydroperoxide reductase
D7006_RS22045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D7006_RS22055	COG3960	tartronate-semialdehyde synthase activity
D7006_RS22060	COG3622	Belongs to the hyi family
D7006_RS22065	COG2084	Dehydrogenase
D7006_RS22070	COG0469	pyruvate kinase activity
D7006_RS22075	COG2954	triphosphatase activity
D7006_RS22100	COG1609	Transcriptional regulator
D7006_RS22115	COG3246	L-lysine catabolic process to acetate
D7006_RS22120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7006_RS22120	COG3321	synthase
D7006_RS22120	COG4221	oxidoreductase activity
D7006_RS22120	COG0604	alcohol dehydrogenase
D7006_RS22130	COG1301	dicarboxylic acid transport
D7006_RS22135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7006_RS22135	COG1648	precorrin-2 dehydrogenase activity
D7006_RS22140	COG0251	oxidation-reduction process
D7006_RS22145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D7006_RS22145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D7006_RS22150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7006_RS22155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS22160	COG1116	anion transmembrane transporter activity
D7006_RS22170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7006_RS22175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7006_RS22185	COG0243	molybdopterin cofactor binding
D7006_RS22190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D7006_RS22205	COG3162	membrane
D7006_RS22210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7006_RS22225	COG5002	protein histidine kinase activity
D7006_RS22230	COG0745	RESPONSE REGULATOR receiver
D7006_RS22235	COG2176	DNA-directed DNA polymerase activity
D7006_RS22235	COG5002	protein histidine kinase activity
D7006_RS22240	COG2267	carboxylic ester hydrolase activity
D7006_RS22260	COG0163	prenyltransferase activity
D7006_RS22265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D7006_RS22280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS22310	COG1024	Enoyl-CoA hydratase
D7006_RS22320	COG0028	Belongs to the TPP enzyme family
D7006_RS22325	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS22335	COG0583	DNA-binding transcription factor activity
D7006_RS22340	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7006_RS22355	COG1335	isochorismatase
D7006_RS22370	COG1858	cytochrome C peroxidase
D7006_RS22380	COG1294	oxidase, subunit
D7006_RS22410	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D7006_RS22420	COG0473	3-isopropylmalate dehydrogenase activity
D7006_RS22430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7006_RS22440	COG4208	sulfate ABC transporter
D7006_RS22445	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7006_RS22455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7006_RS22470	COG0583	DNA-binding transcription factor activity
D7006_RS22580	COG1024	Enoyl-CoA hydratase
D7006_RS22585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D7006_RS22600	COG0242	peptide deformylase activity
D7006_RS22605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D7006_RS22615	COG0101	tRNA pseudouridine synthase activity
D7006_RS22630	COG1074	ATP-dependent DNA helicase activity
D7006_RS22635	COG2887	Belongs to the helicase family. UvrD subfamily
D7006_RS22640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D7006_RS22645	COG3178	'Phosphotransferase
D7006_RS22650	COG2205	protein histidine kinase activity
D7006_RS22660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7006_RS22665	COG1695	Transcriptional regulator
D7006_RS22675	COG0651	ATP synthesis coupled electron transport
D7006_RS22680	COG0650	Formate hydrogenlyase subunit 4
D7006_RS22690	COG0651	ATP synthesis coupled electron transport
D7006_RS22695	COG0649	NAD binding
D7006_RS22700	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7006_RS22705	COG1012	belongs to the aldehyde dehydrogenase family
D7006_RS22710	COG3284	Transcriptional regulator
D7006_RS22720	COG1609	Transcriptional regulator
D7006_RS22740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
D7006_RS22765	COG0583	DNA-binding transcription factor activity
D7006_RS22770	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D7006_RS22775	COG0459	protein refolding
D7006_RS22780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D7006_RS22790	COG2066	Belongs to the glutaminase family
D7006_RS22795	COG4774	siderophore transport
D7006_RS22805	COG0481	GTPase activity
D7006_RS22825	COG0181	hydroxymethylbilane synthase activity
D7006_RS22830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D7006_RS22835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D7006_RS22855	COG2264	protein methyltransferase activity
D7006_RS22885	COG0477	Major facilitator Superfamily
D7006_RS22890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7006_RS22895	COG1609	Transcriptional regulator
D7006_RS22905	COG0435	Glutathione S-transferase
D7006_RS22920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS22925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7006_RS22935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7006_RS22950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7006_RS22960	COG2217	Heavy metal translocating P-type atpase
D7006_RS22980	COG0443	Heat shock 70 kDa protein
D7006_RS22985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7006_RS23000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D7006_RS23030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS23035	COG0577	efflux transmembrane transporter activity
D7006_RS23035	COG1136	(ABC) transporter
D7006_RS23050	COG3128	pkhd-type hydroxylase
D7006_RS23060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7006_RS23065	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D7006_RS23070	COG2080	2 iron, 2 sulfur cluster binding
D7006_RS23090	COG1304	FMN binding
D7006_RS23095	COG2186	Transcriptional regulator
D7006_RS23110	COG0583	DNA-binding transcription factor activity
D7006_RS23140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7006_RS23145	COG1120	ATPase activity
D7006_RS23150	COG4774	siderophore transport
D7006_RS23155	COG1960	acyl-CoA dehydrogenase activity
D7006_RS23165	COG1024	Enoyl-CoA hydratase
D7006_RS23170	COG0583	DNA-binding transcription factor activity
D7006_RS23190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7006_RS23215	COG2267	carboxylic ester hydrolase activity
D7006_RS23220	COG0251	oxidation-reduction process
D7006_RS23225	COG0583	DNA-binding transcription factor activity
D7006_RS23240	COG3386	PFAM SMP-30 Gluconolaconase
D7006_RS23250	COG4214	carbohydrate transport
D7006_RS23265	COG1137	ATPase activity
D7006_RS23275	COG0640	Transcriptional regulator
D7006_RS23310	COG2301	Belongs to the HpcH HpaI aldolase family
D7006_RS23315	COG2030	dehydratase
D7006_RS23340	COG1414	Transcriptional regulator
D7006_RS23395	COG3383	formate dehydrogenase (NAD+) activity
D7006_RS23440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7006_RS23480	COG1522	sequence-specific DNA binding
D7006_RS23490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS23495	COG0842	Transport permease protein
D7006_RS23495	COG1129	ABC transporter
D7006_RS23500	COG0842	Transport permease protein
D7006_RS23505	COG1959	2 iron, 2 sulfur cluster binding
D7006_RS23510	COG2917	probably involved in intracellular septation
D7006_RS23515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D7006_RS23520	COG0142	geranyltranstransferase activity
D7006_RS23525	COG0588	phosphoglycerate mutase activity
D7006_RS23530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D7006_RS23545	COG0284	orotidine-5'-phosphate decarboxylase activity
D7006_RS23555	COG3963	phosphatidate phosphatase activity
D7006_RS23570	COG0484	heat shock protein binding
D7006_RS23580	COG0443	Heat shock 70 kDa protein
D7006_RS23585	COG1335	isochorismatase
D7006_RS23635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D7006_RS23640	COG0792	nuclease activity
D7006_RS23645	COG0189	ligase activity
D7006_RS23655	COG2226	methyltransferase
D7006_RS23660	COG0606	chelatase, subunit chli
D7006_RS23680	COG0497	DNA recombination
D7006_RS23685	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7006_RS23695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D7006_RS23700	COG0849	cell division
D7006_RS23705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D7006_RS23710	COG1181	Belongs to the D-alanine--D-alanine ligase family
D7006_RS23715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D7006_RS23720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D7006_RS23730	COG0657	acetylesterase activity
D7006_RS23735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7006_RS23750	COG3395	kinase activity
D7006_RS23755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D7006_RS23790	COG3655	Transcriptional regulator
D7006_RS23800	COG0702	epimerase
D7006_RS23840	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D7006_RS23870	COG0436	Aminotransferase
D7006_RS23880	COG0747	negative chemotaxis
D7006_RS23885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D7006_RS23890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D7006_RS23900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D7006_RS23915	COG0779	Required for maturation of 30S ribosomal subunits
D7006_RS23930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D7006_RS23935	COG1185	polyribonucleotide nucleotidyltransferase activity
D7006_RS23950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D7006_RS23955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D7006_RS23960	COG0493	'glutamate synthase
D7006_RS23960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7006_RS23970	COG0523	cobalamin synthesis protein
D7006_RS23975	COG1686	Belongs to the peptidase S11 family
D7006_RS23980	COG1132	(ABC) transporter
D7006_RS23995	COG1960	acyl-CoA dehydrogenase activity
D7006_RS24005	COG4191	Histidine kinase
D7006_RS24005	COG0784	Response regulator, receiver
D7006_RS24015	COG0784	Response regulator, receiver
D7006_RS24035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7006_RS24040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7006_RS24040	COG2813	Specifically methylates the guanine in position
D7006_RS24060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7006_RS24105	COG5002	protein histidine kinase activity
D7006_RS24115	COG0573	inorganic phosphate transmembrane transporter activity
D7006_RS24125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D7006_RS24130	COG0704	Plays a role in the regulation of phosphate uptake
D7006_RS24135	COG0745	RESPONSE REGULATOR receiver
D7006_RS24150	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS24155	COG0697	spore germination
D7006_RS24195	COG0739	heme binding
D7006_RS24230	COG0542	response to heat
D7006_RS24255	COG2204	response regulator
D7006_RS24260	COG4191	Histidine kinase
D7006_RS24265	COG1301	dicarboxylic acid transport
D7006_RS24275	COG0840	transmembrane signaling receptor activity
D7006_RS24295	COG0247	lactate metabolic process
D7006_RS24300	COG1139	Iron-sulfur cluster binding protein
D7006_RS24305	COG1556	Lactate utilization protein
D7006_RS24330	COG0583	DNA-binding transcription factor activity
D7006_RS24335	COG0277	FAD linked oxidase domain protein
D7006_RS24345	COG0247	lactate metabolic process
D7006_RS24350	COG0352	thiamine-phosphate diphosphorylase activity
D7006_RS24355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D7006_RS24360	COG0702	epimerase
D7006_RS24370	COG0189	ligase activity
D7006_RS24395	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
D7006_RS24400	COG1229	Formylmethanofuran dehydrogenase subunit A
D7006_RS24420	COG0535	radical SAM domain protein
D7006_RS24425	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
D7006_RS24430	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
D7006_RS24445	COG2205	protein histidine kinase activity
D7006_RS24450	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D7006_RS24460	COG1968	undecaprenyl-diphosphatase activity
D7006_RS24470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D7006_RS24475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D7006_RS24480	COG1702	phosphate starvation-inducible protein PhoH
D7006_RS24485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D7006_RS24490	COG1253	flavin adenine dinucleotide binding
D7006_RS24495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D7006_RS24500	COG1396	sequence-specific DNA binding
D7006_RS24505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D7006_RS24510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D7006_RS24540	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D7006_RS24545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D7006_RS24550	COG1981	membrane
D7006_RS24555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D7006_RS24560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D7006_RS24565	COG0424	maF-like protein
D7006_RS24570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7006_RS24575	COG0237	dephospho-CoA kinase activity
D7006_RS24580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7006_RS24585	COG1331	Highly conserved protein containing a thioredoxin domain
D7006_RS24590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D7006_RS24595	COG0445	tRNA wobble uridine modification
D7006_RS24600	COG0357	Ribosomal RNA small subunit methyltransferase G
D7006_RS24615	COG4957	zinc ion binding
D7006_RS24620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D7006_RS24625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D7006_RS24630	COG1674	ftsk spoiiie
D7006_RS24635	COG0436	Aminotransferase
D7006_RS24640	COG0196	riboflavin kinase activity
D7006_RS24650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D7006_RS24660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D7006_RS24670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D7006_RS24685	COG0275	rRNA processing
D7006_RS24690	COG2001	Belongs to the MraZ family
D7006_RS24695	COG0330	HflC and HflK could
D7006_RS24700	COG1585	Membrane protein implicated in regulation of membrane protease activity
D7006_RS24710	COG0564	pseudouridine synthase activity
D7006_RS24715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D7006_RS24730	COG1028	Short-chain dehydrogenase reductase Sdr
D7006_RS24740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D7006_RS24760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7006_RS24765	COG1132	(ABC) transporter
D7006_RS24775	COG5001	Diguanylate cyclase
D7006_RS24780	COG0045	succinate-CoA ligase (ADP-forming) activity
D7006_RS24780	COG1042	CoA-binding domain protein
D7006_RS24780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D7006_RS24785	COG4566	intracellular signal transduction
D7006_RS24790	COG4566	intracellular signal transduction
D7006_RS24795	COG4191	Histidine kinase
D7006_RS24800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7006_RS24805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D7006_RS24845	COG1024	Enoyl-CoA hydratase
D7006_RS24850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7006_RS24855	COG1309	transcriptional regulator
D7006_RS24860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7006_RS24870	COG1022	Amp-dependent synthetase and ligase
D7006_RS24950	COG3023	N-Acetylmuramoyl-L-alanine amidase
D7006_RS24960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7006_RS24965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
D7006_RS24970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7006_RS25005	COG4181	ATPase activity
D7006_RS25025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D7006_RS25040	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D7006_RS25070	COG0019	diaminopimelate decarboxylase activity
D7006_RS25080	COG0165	Argininosuccinate lyase
D7006_RS25085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7006_RS25090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D7006_RS25100	COG1215	transferase activity, transferring glycosyl groups
D7006_RS25115	COG1846	Transcriptional regulator
D7006_RS25120	COG0138	bifunctional purine biosynthesis protein purh
D7006_RS25125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D7006_RS25135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D7006_RS25140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D7006_RS25140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D7006_RS25150	COG0501	Belongs to the peptidase M48B family
D7006_RS25160	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
D7006_RS25190	COG3842	ATPase activity
D7006_RS25205	COG0037	tRNA processing
D7006_RS25205	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D7006_RS25210	COG2884	Cell division ATP-binding protein ftsE
D7006_RS25235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D7006_RS25245	COG3454	Phosphonate metabolism
D7006_RS25255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D7006_RS25265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP