locus-tag	class	description
LZZ50_RS00010	COG0739	heme binding
LZZ50_RS00025	COG2211	Major facilitator Superfamily
LZZ50_RS00030	COG0708	Exodeoxyribonuclease III
LZZ50_RS00045	COG1192	Involved in chromosome partitioning
LZZ50_RS00050	COG1475	DNA binding
LZZ50_RS00070	COG0463	Glycosyl transferase, family 2
LZZ50_RS00095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZZ50_RS00105	COG0018	arginyl-trna synthetase
LZZ50_RS00120	COG4221	oxidoreductase activity
LZZ50_RS00135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZZ50_RS00135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZZ50_RS00140	COG1166	arginine decarboxylase activity
LZZ50_RS00145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LZZ50_RS00180	COG0606	chelatase, subunit chli
LZZ50_RS00195	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZZ50_RS00245	COG1090	epimerase
LZZ50_RS00255	COG0642	Histidine kinase
LZZ50_RS00295	COG0628	permease
LZZ50_RS00300	COG1011	Hydrolase
LZZ50_RS00305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZZ50_RS00335	COG2197	response regulator
LZZ50_RS00340	COG4585	Histidine kinase
LZZ50_RS00345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS00350	COG1136	(ABC) transporter
LZZ50_RS00375	COG0697	spore germination
LZZ50_RS00395	COG0180	Tryptophanyl-tRNA synthetase
LZZ50_RS00400	COG3237	CsbD-like
LZZ50_RS00440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LZZ50_RS00455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LZZ50_RS00460	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZZ50_RS00460	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZZ50_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZZ50_RS00525	COG1199	ATP-dependent helicase activity
LZZ50_RS00585	COG0625	glutathione transferase activity
LZZ50_RS00620	COG4555	ABC transporter
LZZ50_RS00625	COG0596	Alpha beta hydrolase
LZZ50_RS00630	COG1476	TRANSCRIPTIONal
LZZ50_RS00640	COG5290	Psort location Cytoplasmic, score
LZZ50_RS00665	COG1131	(ABC) transporter
LZZ50_RS00670	COG0842	Transport permease protein
LZZ50_RS00675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LZZ50_RS00685	COG1607	acyl-coa hydrolase
LZZ50_RS00700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZZ50_RS00705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZZ50_RS00715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZZ50_RS00715	COG0045	succinate-CoA ligase (ADP-forming) activity
LZZ50_RS00715	COG1042	CoA-binding domain protein
LZZ50_RS00730	COG1629	transport
LZZ50_RS00730	COG4771	TonB-dependent receptor
LZZ50_RS00735	COG2239	Acts as a magnesium transporter
LZZ50_RS00745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZZ50_RS00750	COG3387	PFAM Glycoside hydrolase 15-related
LZZ50_RS00765	COG3100	YcgL domain-containing protein
LZZ50_RS00770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZZ50_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS00825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZZ50_RS00840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZZ50_RS00910	COG0154	amidase activity
LZZ50_RS00920	COG0604	alcohol dehydrogenase
LZZ50_RS00925	COG1309	transcriptional regulator
LZZ50_RS00960	COG0210	DNA helicase
LZZ50_RS00970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZZ50_RS00975	COG0583	DNA-binding transcription factor activity
LZZ50_RS00980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZZ50_RS00990	COG2159	amidohydrolase
LZZ50_RS01015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS01040	COG3540	Alkaline phosphatase
LZZ50_RS01050	COG2091	lysine biosynthetic process via aminoadipic acid
LZZ50_RS01080	COG1940	carbohydrate kinase activity
LZZ50_RS01090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZZ50_RS01100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZZ50_RS01105	COG3162	membrane
LZZ50_RS01145	COG3507	Belongs to the glycosyl hydrolase 43 family
LZZ50_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS01165	COG0179	Fumarylacetoacetate (FAA) hydrolase
LZZ50_RS01170	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS01175	COG3254	rhamnose metabolic process
LZZ50_RS01180	COG0738	Major facilitator superfamily
LZZ50_RS01185	COG1414	Transcriptional regulator
LZZ50_RS01190	COG1971	Probably functions as a manganese efflux pump
LZZ50_RS01195	COG2205	protein histidine kinase activity
LZZ50_RS01195	COG0784	Response regulator, receiver
LZZ50_RS01200	COG3459	Glycosyltransferase 36 associated
LZZ50_RS01205	COG2211	Major facilitator Superfamily
LZZ50_RS01210	COG3265	gluconokinase activity
LZZ50_RS01220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZZ50_RS01240	COG2911	Protein conserved in bacteria
LZZ50_RS01245	COG0729	surface antigen
LZZ50_RS01250	COG4771	TonB-dependent receptor
LZZ50_RS01255	COG0457	Tetratricopeptide repeat
LZZ50_RS01270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZZ50_RS01280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZZ50_RS01280	COG0519	Catalyzes the synthesis of GMP from XMP
LZZ50_RS01290	COG0805	protein transport
LZZ50_RS01295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZZ50_RS01300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZZ50_RS01310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LZZ50_RS01325	COG2974	May be involved in recombination
LZZ50_RS01330	COG0037	tRNA processing
LZZ50_RS01335	COG2115	Belongs to the xylose isomerase family
LZZ50_RS01345	COG3661	Belongs to the glycosyl hydrolase 67 family
LZZ50_RS01355	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS01365	COG1472	Belongs to the glycosyl hydrolase 3 family
LZZ50_RS01370	COG0246	Mannitol dehydrogenase
LZZ50_RS01385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZZ50_RS01420	COG3386	PFAM SMP-30 Gluconolaconase
LZZ50_RS01430	COG3250	beta-galactosidase activity
LZZ50_RS01435	COG1904	glucuronate isomerase
LZZ50_RS01455	COG2211	Major facilitator Superfamily
LZZ50_RS01485	COG0604	alcohol dehydrogenase
LZZ50_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS01485	COG3321	synthase
LZZ50_RS01490	COG2937	Belongs to the GPAT DAPAT family
LZZ50_RS01500	COG1609	Transcriptional regulator
LZZ50_RS01520	COG0284	orotidine-5'-phosphate decarboxylase activity
LZZ50_RS01525	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LZZ50_RS01530	COG3132	Protein of unknown function, DUF480
LZZ50_RS01545	COG0210	DNA helicase
LZZ50_RS01550	COG1435	thymidine kinase activity
LZZ50_RS01560	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LZZ50_RS01570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZZ50_RS01600	COG3135	benzoate transporter
LZZ50_RS01625	COG0676	glucose-6-phosphate 1-epimerase activity
LZZ50_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS01650	COG0730	response to heat
LZZ50_RS01675	COG0302	gtp cyclohydrolase
LZZ50_RS01690	COG1566	PFAM secretion protein HlyD family protein
LZZ50_RS01700	COG1289	transmembrane transporter activity
LZZ50_RS01705	COG0477	Major facilitator Superfamily
LZZ50_RS01715	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LZZ50_RS01720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZZ50_RS01780	COG0564	pseudouridine synthase activity
LZZ50_RS01835	COG1074	ATP-dependent DNA helicase activity
LZZ50_RS01840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZZ50_RS01875	COG1127	ABC transporter
LZZ50_RS01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZZ50_RS01885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZZ50_RS01900	COG2853	Lipoprotein
LZZ50_RS01910	COG0386	Belongs to the glutathione peroxidase family
LZZ50_RS01920	COG1322	Protein conserved in bacteria
LZZ50_RS01925	COG0625	glutathione transferase activity
LZZ50_RS01935	COG0531	amino acid
LZZ50_RS01940	COG3537	Alpha-1,2-mannosidase
LZZ50_RS01955	COG3706	GGDEF domain
LZZ50_RS01960	COG3835	regulator
LZZ50_RS01965	COG1929	Belongs to the glycerate kinase type-1 family
LZZ50_RS02020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZZ50_RS02025	COG0861	Integral membrane protein TerC family
LZZ50_RS02035	COG0584	glycerophosphoryl diester phosphodiesterase
LZZ50_RS02045	COG0671	phosphoesterase, PA-phosphatase related
LZZ50_RS02050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LZZ50_RS02055	COG0726	polysaccharide deacetylase
LZZ50_RS02060	COG0706	membrane insertase activity
LZZ50_RS02075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZZ50_RS02090	COG0187	DNA topoisomerase II activity
LZZ50_RS02100	COG0501	Belongs to the peptidase M48B family
LZZ50_RS02135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LZZ50_RS02145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZZ50_RS02175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZZ50_RS02180	COG0793	Belongs to the peptidase S41A family
LZZ50_RS02185	COG4942	peptidase
LZZ50_RS02195	COG2234	aminopeptidase activity
LZZ50_RS02205	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZZ50_RS02210	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZZ50_RS02215	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZZ50_RS02220	COG1064	alcohol dehydrogenase
LZZ50_RS02230	COG0493	'glutamate synthase
LZZ50_RS02235	COG0070	glutamate synthase
LZZ50_RS02235	COG0067	glutamate synthase
LZZ50_RS02235	COG0069	glutamate synthase activity
LZZ50_RS02265	COG1741	Belongs to the pirin family
LZZ50_RS02270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LZZ50_RS02285	COG3459	Glycosyltransferase 36 associated
LZZ50_RS02335	COG1111	helicase
LZZ50_RS02335	COG1205	dead DEAH box helicase
LZZ50_RS02340	COG1272	protein, Hemolysin III
LZZ50_RS02365	COG4221	oxidoreductase activity
LZZ50_RS02385	COG0583	DNA-binding transcription factor activity
LZZ50_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS02400	COG1733	regulation of RNA biosynthetic process
LZZ50_RS02450	COG1733	regulation of RNA biosynthetic process
LZZ50_RS02455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LZZ50_RS02460	COG3237	CsbD-like
LZZ50_RS02495	COG0657	acetylesterase activity
LZZ50_RS02505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZZ50_RS02550	COG0714	Associated with various cellular activities
LZZ50_RS02585	COG1309	transcriptional regulator
LZZ50_RS02615	COG4772	TonB-dependent receptor
LZZ50_RS02625	COG0662	Cupin 2, conserved barrel domain protein
LZZ50_RS02635	COG3284	Transcriptional regulator
LZZ50_RS02640	COG1012	belongs to the aldehyde dehydrogenase family
LZZ50_RS02670	COG1304	FMN binding
LZZ50_RS02690	COG1755	Isoprenylcysteine carboxyl methyltransferase
LZZ50_RS02695	COG4585	Histidine kinase
LZZ50_RS02700	COG2197	response regulator
LZZ50_RS02720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LZZ50_RS02880	COG0366	Alpha amylase catalytic
LZZ50_RS02885	COG0366	Alpha amylase catalytic
LZZ50_RS02890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZZ50_RS02930	COG2755	lipolytic protein G-D-S-L family
LZZ50_RS02940	COG2755	lipolytic protein G-D-S-L family
LZZ50_RS02940	COG0657	acetylesterase activity
LZZ50_RS02950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZZ50_RS02965	COG3507	Belongs to the glycosyl hydrolase 43 family
LZZ50_RS02970	COG1609	Transcriptional regulator
LZZ50_RS02975	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LZZ50_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS02990	COG2755	lipolytic protein G-D-S-L family
LZZ50_RS03005	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LZZ50_RS03020	COG3186	Phenylalanine-4-hydroxylase
LZZ50_RS03025	COG1522	sequence-specific DNA binding
LZZ50_RS03035	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZZ50_RS03045	COG1119	ATPase activity
LZZ50_RS03060	COG0517	IMP dehydrogenase activity
LZZ50_RS03060	COG1125	glycine betaine transport
LZZ50_RS03075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LZZ50_RS03080	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LZZ50_RS03110	COG0489	protein tyrosine kinase activity
LZZ50_RS03115	COG2062	phosphohistidine phosphatase, SixA
LZZ50_RS03125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZZ50_RS03150	COG1881	PFAM PEBP family protein
LZZ50_RS03165	COG0174	glutamine synthetase
LZZ50_RS03170	COG0347	Belongs to the P(II) protein family
LZZ50_RS03175	COG0004	ammonium transporteR
LZZ50_RS03180	COG3852	Histidine kinase
LZZ50_RS03185	COG2204	response regulator
LZZ50_RS03190	COG2032	superoxide dismutase activity
LZZ50_RS03195	COG2032	superoxide dismutase activity
LZZ50_RS03200	COG0346	lactoylglutathione lyase activity
LZZ50_RS03210	COG0183	Belongs to the thiolase family
LZZ50_RS03250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZZ50_RS03260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LZZ50_RS03270	COG0028	Belongs to the TPP enzyme family
LZZ50_RS03275	COG2205	protein histidine kinase activity
LZZ50_RS03280	COG2204	response regulator
LZZ50_RS03300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZZ50_RS03315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZZ50_RS03325	COG0596	Alpha beta hydrolase
LZZ50_RS03330	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZZ50_RS03335	COG0318	PFAM AMP-dependent synthetase and ligase
LZZ50_RS03340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZZ50_RS03375	COG0564	pseudouridine synthase activity
LZZ50_RS03405	COG0339	signal peptide processing
LZZ50_RS03410	COG0681	Belongs to the peptidase S26 family
LZZ50_RS03425	COG0475	glutathione-regulated potassium exporter activity
LZZ50_RS03430	COG0583	DNA-binding transcription factor activity
LZZ50_RS03435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZZ50_RS03440	COG2224	Isocitrate lyase
LZZ50_RS03475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LZZ50_RS03480	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS03535	COG0523	cobalamin synthesis protein
LZZ50_RS03545	COG0697	spore germination
LZZ50_RS03555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZZ50_RS03565	COG1846	Transcriptional regulator
LZZ50_RS03570	COG1764	response to oxidative stress
LZZ50_RS03575	COG0596	Alpha beta hydrolase
LZZ50_RS03595	COG0656	L-ascorbic acid biosynthetic process
LZZ50_RS03600	COG2130	NADP-dependent
LZZ50_RS03615	COG1187	pseudouridine synthase activity
LZZ50_RS03625	COG1643	Atp-dependent helicase
LZZ50_RS03630	COG0840	transmembrane signaling receptor activity
LZZ50_RS03635	COG4807	Protein conserved in bacteria
LZZ50_RS03640	COG2351	hydroxyisourate hydrolase activity
LZZ50_RS03645	COG2072	flavoprotein involved in K transport
LZZ50_RS03665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZZ50_RS03715	COG1957	nucleoside hydrolase
LZZ50_RS03740	COG0084	hydrolase, TatD family'
LZZ50_RS03750	COG0583	DNA-binding transcription factor activity
LZZ50_RS03755	COG2814	Major facilitator Superfamily
LZZ50_RS03765	COG2267	carboxylic ester hydrolase activity
LZZ50_RS03785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LZZ50_RS03790	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS03810	COG2223	nitrite transmembrane transporter activity
LZZ50_RS03815	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS03820	COG2205	protein histidine kinase activity
LZZ50_RS03825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS03845	COG0577	efflux transmembrane transporter activity
LZZ50_RS03850	COG1136	(ABC) transporter
LZZ50_RS03850	COG0577	efflux transmembrane transporter activity
LZZ50_RS03895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZZ50_RS03900	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZZ50_RS03905	COG0583	DNA-binding transcription factor activity
LZZ50_RS03930	COG0702	epimerase
LZZ50_RS03935	COG1733	regulation of RNA biosynthetic process
LZZ50_RS03945	COG0840	transmembrane signaling receptor activity
LZZ50_RS04015	COG0129	dihydroxy-acid dehydratase activity
LZZ50_RS04035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZZ50_RS04040	COG2814	Major facilitator Superfamily
LZZ50_RS04090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LZZ50_RS04120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LZZ50_RS04125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LZZ50_RS04135	COG3485	protocatechuate 3,4-dioxygenase
LZZ50_RS04140	COG3485	protocatechuate 3,4-dioxygenase
LZZ50_RS04150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZZ50_RS04155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LZZ50_RS04165	COG1414	Transcriptional regulator
LZZ50_RS04175	COG0657	acetylesterase activity
LZZ50_RS04185	COG0445	tRNA wobble uridine modification
LZZ50_RS04195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LZZ50_RS04235	COG0156	8-amino-7-oxononanoate synthase activity
LZZ50_RS04240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LZZ50_RS04245	COG1040	competence protein
LZZ50_RS04265	COG3264	Mechanosensitive ion channel
LZZ50_RS04265	COG1511	domain protein
LZZ50_RS04270	COG1368	sulfuric ester hydrolase activity
LZZ50_RS04275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZZ50_RS04280	COG2354	Protein conserved in bacteria
LZZ50_RS04290	COG0297	glycogen (starch) synthase activity
LZZ50_RS04295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZZ50_RS04300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZZ50_RS04325	COG0702	epimerase
LZZ50_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS04370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZZ50_RS04375	COG4221	oxidoreductase activity
LZZ50_RS04385	COG0513	Belongs to the DEAD box helicase family
LZZ50_RS04390	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZZ50_RS04405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LZZ50_RS04420	COG3104	oligopeptide transport
LZZ50_RS04450	COG2852	Protein conserved in bacteria
LZZ50_RS04455	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LZZ50_RS04470	COG1320	monovalent cation:proton antiporter activity
LZZ50_RS04475	COG2212	antiporter activity
LZZ50_RS04485	COG0651	ATP synthesis coupled electron transport
LZZ50_RS04490	COG1006	Multisubunit Na H antiporter MnhC subunit
LZZ50_RS04495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZZ50_RS04495	COG2111	Na H antiporter
LZZ50_RS04530	COG0484	heat shock protein binding
LZZ50_RS04550	COG1597	lipid kinase activity
LZZ50_RS04685	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LZZ50_RS04760	COG0840	transmembrane signaling receptor activity
LZZ50_RS04775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZZ50_RS04785	COG4221	oxidoreductase activity
LZZ50_RS04795	COG0583	DNA-binding transcription factor activity
LZZ50_RS04800	COG1301	dicarboxylic acid transport
LZZ50_RS04805	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS04830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZZ50_RS04835	COG0134	indole-3-glycerol-phosphate synthase activity
LZZ50_RS04845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZZ50_RS04860	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LZZ50_RS04870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LZZ50_RS04885	COG1051	belongs to the nudix hydrolase family
LZZ50_RS04925	COG0316	Belongs to the HesB IscA family
LZZ50_RS04940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZZ50_RS04965	COG2814	Major facilitator Superfamily
LZZ50_RS04970	COG1289	transmembrane transporter activity
LZZ50_RS04975	COG0151	Belongs to the GarS family
LZZ50_RS04980	COG0138	bifunctional purine biosynthesis protein purh
LZZ50_RS05000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LZZ50_RS05020	COG2264	protein methyltransferase activity
LZZ50_RS05035	COG0439	Biotin carboxylase
LZZ50_RS05045	COG0511	ligase activity, forming carbon-carbon bonds
LZZ50_RS05050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LZZ50_RS05060	COG1324	tolerance protein
LZZ50_RS05065	COG2356	endonuclease I
LZZ50_RS05090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZZ50_RS05115	COG3712	iron ion homeostasis
LZZ50_RS05140	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LZZ50_RS05170	COG2353	YceI-like domain
LZZ50_RS05190	COG3052	prosthetic group binding
LZZ50_RS05225	COG1802	Transcriptional regulator
LZZ50_RS05230	COG0546	phosphoglycolate phosphatase activity
LZZ50_RS05285	COG0210	DNA helicase
LZZ50_RS05305	COG1595	DNA-templated transcription, initiation
LZZ50_RS05320	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS05320	COG1506	peptidase
LZZ50_RS05360	COG0435	Glutathione S-transferase
LZZ50_RS05395	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS05395	COG1506	peptidase
LZZ50_RS05445	COG0697	spore germination
LZZ50_RS05460	COG4305	rare lipoprotein A
LZZ50_RS05465	COG1113	amino acid transport
LZZ50_RS05525	COG0840	transmembrane signaling receptor activity
LZZ50_RS05530	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZZ50_RS05530	COG5297	Belongs to the glycosyl hydrolase family 6
LZZ50_RS05535	COG0659	secondary active sulfate transmembrane transporter activity
LZZ50_RS05550	COG2943	transferase activity, transferring hexosyl groups
LZZ50_RS05560	COG3275	phosphorelay sensor kinase activity
LZZ50_RS05570	COG0181	hydroxymethylbilane synthase activity
LZZ50_RS05595	COG1505	serine-type exopeptidase activity
LZZ50_RS05605	COG0436	Aminotransferase
LZZ50_RS05615	COG2832	Protein of unknown function (DUF454)
LZZ50_RS05625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LZZ50_RS05640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LZZ50_RS05670	COG2226	methyltransferase
LZZ50_RS05675	COG3300	MHYT domain
LZZ50_RS05675	COG5001	Diguanylate cyclase
LZZ50_RS05680	COG0308	aminopeptidase N
LZZ50_RS05715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LZZ50_RS05725	COG3284	Transcriptional regulator
LZZ50_RS05730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZZ50_RS05735	COG1077	Cell shape determining protein MreB Mrl
LZZ50_RS05745	COG1792	Involved in formation and maintenance of cell shape
LZZ50_RS05760	COG0772	Belongs to the SEDS family
LZZ50_RS05770	COG2951	lytic endotransglycosylase activity
LZZ50_RS05775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZZ50_RS05780	COG1686	Belongs to the peptidase S11 family
LZZ50_RS05795	COG2921	Belongs to the UPF0250 family
LZZ50_RS05800	COG0321	lipoyl(octanoyl) transferase activity
LZZ50_RS05805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZZ50_RS05820	COG0583	DNA-binding transcription factor activity
LZZ50_RS05830	COG1056	cytidyltransferase-related domain
LZZ50_RS05830	COG1051	belongs to the nudix hydrolase family
LZZ50_RS05845	COG2813	Specifically methylates the guanine in position
LZZ50_RS05865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LZZ50_RS05870	COG0673	inositol 2-dehydrogenase activity
LZZ50_RS05875	COG2823	Periplasmic or secreted lipoprotein
LZZ50_RS05880	COG4251	negative regulation of phosphorylation
LZZ50_RS05885	COG0784	Response regulator, receiver
LZZ50_RS05890	COG4191	Histidine kinase
LZZ50_RS05895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZZ50_RS05900	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS05945	COG1459	type II secretion system
LZZ50_RS05970	COG3156	type II secretion system protein K
LZZ50_RS05995	COG3250	beta-galactosidase activity
LZZ50_RS06010	COG2188	Transcriptional regulator
LZZ50_RS06020	COG1609	Transcriptional regulator
LZZ50_RS06025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZZ50_RS06030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZZ50_RS06045	COG0617	tRNA 3'-terminal CCA addition
LZZ50_RS06060	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LZZ50_RS06065	COG1012	belongs to the aldehyde dehydrogenase family
LZZ50_RS06070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZZ50_RS06080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZZ50_RS06095	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZZ50_RS06115	COG2205	protein histidine kinase activity
LZZ50_RS06135	COG3920	Histidine kinase
LZZ50_RS06145	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LZZ50_RS06150	COG3791	Glutathione-dependent formaldehyde-activating
LZZ50_RS06160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZZ50_RS06170	COG0697	spore germination
LZZ50_RS06185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LZZ50_RS06190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LZZ50_RS06195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LZZ50_RS06200	COG2205	protein histidine kinase activity
LZZ50_RS06205	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS06210	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS06210	COG1506	peptidase
LZZ50_RS06210	COG4946	Tricorn protease homolog
LZZ50_RS06220	COG0277	FAD linked oxidase domain protein
LZZ50_RS06225	COG1988	membrane-bound metal-dependent
LZZ50_RS06230	COG0792	nuclease activity
LZZ50_RS06265	COG3116	cell division
LZZ50_RS06275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LZZ50_RS06280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZZ50_RS06285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LZZ50_RS06300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZZ50_RS06305	COG1181	Belongs to the D-alanine--D-alanine ligase family
LZZ50_RS06310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZZ50_RS06335	COG0739	heme binding
LZZ50_RS06340	COG0653	protein targeting
LZZ50_RS06350	COG0494	nUDIX hydrolase
LZZ50_RS06365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZZ50_RS06370	COG3321	synthase
LZZ50_RS06370	COG0604	alcohol dehydrogenase
LZZ50_RS06370	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS06385	COG0366	Alpha amylase catalytic
LZZ50_RS06425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LZZ50_RS06460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LZZ50_RS06475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZZ50_RS06480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZZ50_RS06490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZZ50_RS06495	COG0667	Aldo Keto reductase
LZZ50_RS06505	COG4771	TonB-dependent receptor
LZZ50_RS06530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LZZ50_RS06535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LZZ50_RS06545	COG2175	clavaminate synthase activity
LZZ50_RS06555	COG4181	ATPase activity
LZZ50_RS06570	COG0642	Histidine kinase
LZZ50_RS06580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZZ50_RS06600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LZZ50_RS06605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LZZ50_RS06615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LZZ50_RS06620	COG2967	ApaG domain
LZZ50_RS06625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZZ50_RS06630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LZZ50_RS06640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LZZ50_RS06645	COG0123	including yeast histone deacetylase and acetoin utilization protein
LZZ50_RS06650	COG2096	Adenosyltransferase
LZZ50_RS06660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZZ50_RS06665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZZ50_RS06695	COG3384	dioxygenase
LZZ50_RS06700	COG0583	DNA-binding transcription factor activity
LZZ50_RS06705	COG0318	PFAM AMP-dependent synthetase and ligase
LZZ50_RS06715	COG1024	Enoyl-CoA hydratase
LZZ50_RS06765	COG0697	spore germination
LZZ50_RS06770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZZ50_RS06795	COG2197	response regulator
LZZ50_RS06805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZZ50_RS06815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LZZ50_RS06820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZZ50_RS06825	COG0583	DNA-binding transcription factor activity
LZZ50_RS06830	COG3634	alkyl hydroperoxide reductase activity
LZZ50_RS06860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZZ50_RS06860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZZ50_RS06890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LZZ50_RS06930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZZ50_RS06935	COG1404	Belongs to the peptidase S8 family
LZZ50_RS06940	COG1404	Belongs to the peptidase S8 family
LZZ50_RS06945	COG1404	Belongs to the peptidase S8 family
LZZ50_RS06950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LZZ50_RS06970	COG1295	ribonuclease BN
LZZ50_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZZ50_RS06980	COG1254	Belongs to the acylphosphatase family
LZZ50_RS06995	COG0521	Mo-molybdopterin cofactor biosynthetic process
LZZ50_RS07005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LZZ50_RS07010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LZZ50_RS07020	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LZZ50_RS07035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZZ50_RS07040	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LZZ50_RS07045	COG0193	aminoacyl-tRNA hydrolase activity
LZZ50_RS07070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZZ50_RS07080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZZ50_RS07085	COG0250	Participates in transcription elongation, termination and antitermination
LZZ50_RS07090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LZZ50_RS07095	COG0081	regulation of translation
LZZ50_RS07100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LZZ50_RS07105	COG0222	ribosome binding
LZZ50_RS07115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LZZ50_RS07120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LZZ50_RS07130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZZ50_RS07135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZZ50_RS07140	COG0051	transcription antitermination factor activity, RNA binding
LZZ50_RS07160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LZZ50_RS07170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LZZ50_RS07185	COG0255	Belongs to the universal ribosomal protein uL29 family
LZZ50_RS07200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LZZ50_RS07220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LZZ50_RS07235	COG1841	ribosomal large subunit assembly
LZZ50_RS07245	COG0201	protein transport
LZZ50_RS07270	COG0203	ribosomal protein L17
LZZ50_RS07280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LZZ50_RS07290	COG0154	amidase activity
LZZ50_RS07300	COG1217	gtp-binding protein TYPA
LZZ50_RS07305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZZ50_RS07315	COG0625	glutathione transferase activity
LZZ50_RS07330	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS07330	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZZ50_RS07335	COG0604	alcohol dehydrogenase
LZZ50_RS07340	COG2885	chlorophyll binding
LZZ50_RS07365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LZZ50_RS07370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZZ50_RS07375	COG4208	sulfate ABC transporter
LZZ50_RS07380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LZZ50_RS07410	COG0406	alpha-ribazole phosphatase activity
LZZ50_RS07420	COG0285	dihydrofolate synthase activity
LZZ50_RS07440	COG2833	Protein of unknown function (DUF455)
LZZ50_RS07445	COG3291	Pkd domain containing protein
LZZ50_RS07455	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZZ50_RS07460	COG0671	phosphoesterase, PA-phosphatase related
LZZ50_RS07465	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS07475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LZZ50_RS07490	COG4783	chaperone-mediated protein folding
LZZ50_RS07505	COG0473	3-isopropylmalate dehydrogenase activity
LZZ50_RS07545	COG3852	Histidine kinase
LZZ50_RS07555	COG0544	peptidyl-prolyl cis-trans isomerase activity
LZZ50_RS07565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZZ50_RS07595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZZ50_RS07605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZZ50_RS07625	COG0631	protein serine/threonine phosphatase activity
LZZ50_RS07640	COG0859	PFAM glycosyl transferase family 9
LZZ50_RS07650	COG1234	tRNA 3'-trailer cleavage
LZZ50_RS07655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LZZ50_RS07660	COG0315	cyclic pyranopterin monophosphate synthase activity
LZZ50_RS07665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LZZ50_RS07670	COG0314	molybdopterin synthase activity
LZZ50_RS07725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LZZ50_RS07730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LZZ50_RS07735	COG0537	adenosine 5'-monophosphoramidase activity
LZZ50_RS07755	COG0714	Associated with various cellular activities
LZZ50_RS07775	COG0424	maF-like protein
LZZ50_RS07780	COG1399	metal-binding, possibly nucleic acid-binding protein
LZZ50_RS07785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LZZ50_RS07790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZZ50_RS07800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LZZ50_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS07820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZZ50_RS07825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZZ50_RS07850	COG3829	transcription factor binding
LZZ50_RS07890	COG2373	Large extracellular alpha-helical protein
LZZ50_RS07915	COG4953	penicillin-binding protein 1C
LZZ50_RS07925	COG0678	peroxiredoxin activity
LZZ50_RS07945	COG0330	HflC and HflK could
LZZ50_RS07950	COG0330	HflC and HflK could
LZZ50_RS07965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LZZ50_RS07970	COG0308	aminopeptidase N
LZZ50_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS08000	COG1309	transcriptional regulator
LZZ50_RS08030	COG0501	Belongs to the peptidase M48B family
LZZ50_RS08040	COG1309	transcriptional regulator
LZZ50_RS08050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZZ50_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS08070	COG3537	Alpha-1,2-mannosidase
LZZ50_RS08110	COG2323	membrane
LZZ50_RS08125	COG2271	Major facilitator Superfamily
LZZ50_RS08150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LZZ50_RS08155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LZZ50_RS08160	COG2080	2 iron, 2 sulfur cluster binding
LZZ50_RS08220	COG0587	DNA-directed DNA polymerase activity
LZZ50_RS08240	COG1297	OPT oligopeptide transporter protein
LZZ50_RS08260	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS08260	COG1506	peptidase
LZZ50_RS08275	COG1917	Cupin 2, conserved barrel domain protein
LZZ50_RS08275	COG2207	Transcriptional regulator
LZZ50_RS08280	COG0753	catalase activity
LZZ50_RS08285	COG0656	L-ascorbic acid biosynthetic process
LZZ50_RS08310	COG0714	Associated with various cellular activities
LZZ50_RS08315	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LZZ50_RS08320	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LZZ50_RS08325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZZ50_RS08325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZZ50_RS08330	COG2814	Major facilitator Superfamily
LZZ50_RS08350	COG2194	sulfuric ester hydrolase activity
LZZ50_RS08360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZZ50_RS08365	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS08370	COG5002	protein histidine kinase activity
LZZ50_RS08385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LZZ50_RS08390	COG2894	cell division
LZZ50_RS08395	COG0850	regulation of cytokinetic process
LZZ50_RS08405	COG4585	Histidine kinase
LZZ50_RS08410	COG2197	response regulator
LZZ50_RS08425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZZ50_RS08460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LZZ50_RS08470	COG1595	DNA-templated transcription, initiation
LZZ50_RS08480	COG1946	Acyl-CoA thioesterase
LZZ50_RS08485	COG1024	Enoyl-CoA hydratase
LZZ50_RS08495	COG0824	Thioesterase
LZZ50_RS08500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZZ50_RS08510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LZZ50_RS08515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LZZ50_RS08525	COG0728	peptidoglycan biosynthetic process
LZZ50_RS08530	COG0196	riboflavin kinase activity
LZZ50_RS08540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LZZ50_RS08545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LZZ50_RS08560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZZ50_RS08565	COG1845	cytochrome c oxidase, subunit III
LZZ50_RS08570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZZ50_RS08585	COG3152	Membrane
LZZ50_RS08595	COG2207	Transcriptional regulator
LZZ50_RS08600	COG0326	Molecular chaperone. Has ATPase activity
LZZ50_RS08610	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS08615	COG1366	Belongs to the anti-sigma-factor antagonist family
LZZ50_RS08620	COG1366	Belongs to the anti-sigma-factor antagonist family
LZZ50_RS08625	COG2172	sigma factor antagonist activity
LZZ50_RS08655	COG4771	TonB-dependent receptor
LZZ50_RS08665	COG5507	3-demethylubiquinone-9 3-methyltransferase
LZZ50_RS08670	COG2205	protein histidine kinase activity
LZZ50_RS08680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZZ50_RS08685	COG2205	protein histidine kinase activity
LZZ50_RS08685	COG3437	response regulator, receiver
LZZ50_RS08685	COG3850	Histidine kinase
LZZ50_RS08685	COG4999	Histidine kinase
LZZ50_RS08690	COG0784	Response regulator, receiver
LZZ50_RS08690	COG4191	Histidine kinase
LZZ50_RS08720	COG3534	alpha-L-arabinofuranosidase
LZZ50_RS08735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZZ50_RS08760	COG0336	Belongs to the RNA methyltransferase TrmD family
LZZ50_RS08770	COG0534	Mate efflux family protein
LZZ50_RS08780	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LZZ50_RS08790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZZ50_RS08805	COG3250	beta-galactosidase activity
LZZ50_RS08810	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LZZ50_RS08830	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS08870	COG0457	Tetratricopeptide repeat
LZZ50_RS08880	COG1024	Enoyl-CoA hydratase
LZZ50_RS08880	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZZ50_RS08895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZZ50_RS08900	COG0481	GTPase activity
LZZ50_RS08915	COG0571	ribonuclease III activity
LZZ50_RS08920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LZZ50_RS08930	COG1381	Involved in DNA repair and RecF pathway recombination
LZZ50_RS08950	COG2954	triphosphatase activity
LZZ50_RS08955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LZZ50_RS08960	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LZZ50_RS08965	COG3046	protein related to deoxyribodipyrimidine photolyase
LZZ50_RS08970	COG1472	Belongs to the glycosyl hydrolase 3 family
LZZ50_RS08975	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZZ50_RS08980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LZZ50_RS08985	COG1278	Cold shock
LZZ50_RS08990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZZ50_RS09000	COG1201	RNA secondary structure unwinding
LZZ50_RS09005	COG1793	dna ligase
LZZ50_RS09015	COG1793	dna ligase
LZZ50_RS09015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LZZ50_RS09050	COG0183	Belongs to the thiolase family
LZZ50_RS09070	COG1451	nucleotide metabolic process
LZZ50_RS09075	COG5487	UPF0391 membrane protein
LZZ50_RS09085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LZZ50_RS09130	COG1047	Peptidyl-prolyl cis-trans
LZZ50_RS09140	COG2824	Alkylphosphonate utilization operon protein PhnA
LZZ50_RS09160	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS09165	COG2814	Major facilitator Superfamily
LZZ50_RS09200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZZ50_RS09200	COG0392	lysyltransferase activity
LZZ50_RS09210	COG0251	oxidation-reduction process
LZZ50_RS09215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZZ50_RS09230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZZ50_RS09255	COG1595	DNA-templated transcription, initiation
LZZ50_RS09270	COG2878	Part of a membrane complex involved in electron transport
LZZ50_RS09280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZZ50_RS09280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZZ50_RS09295	COG1131	(ABC) transporter
LZZ50_RS09300	COG0346	lactoylglutathione lyase activity
LZZ50_RS09320	COG0833	amino acid
LZZ50_RS09325	COG2040	homocysteine
LZZ50_RS09345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LZZ50_RS09365	COG1695	Transcriptional regulator
LZZ50_RS09390	COG1981	membrane
LZZ50_RS09400	COG0825	malonyl-CoA metabolic process
LZZ50_RS09415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZZ50_RS09420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZZ50_RS09430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZZ50_RS09445	COG0750	zinc metalloprotease
LZZ50_RS09450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LZZ50_RS09455	COG0575	Belongs to the CDS family
LZZ50_RS09465	COG0233	cytoplasmic translational termination
LZZ50_RS09470	COG0528	UMP kinase activity
LZZ50_RS09480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZZ50_RS09485	COG0052	Belongs to the universal ribosomal protein uS2 family
LZZ50_RS09540	COG1393	Belongs to the ArsC family
LZZ50_RS09545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZZ50_RS09555	COG0367	asparagine synthase
LZZ50_RS09565	COG4774	siderophore transport
LZZ50_RS09605	COG1566	PFAM secretion protein HlyD family protein
LZZ50_RS09610	COG2814	Major facilitator Superfamily
LZZ50_RS09670	COG0339	signal peptide processing
LZZ50_RS09675	COG0386	Belongs to the glutathione peroxidase family
LZZ50_RS09705	COG0288	reversible hydration of carbon dioxide
LZZ50_RS09715	COG2839	Protein conserved in bacteria
LZZ50_RS09735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZZ50_RS09740	COG0084	hydrolase, TatD family'
LZZ50_RS09755	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS09770	COG0367	asparagine synthase
LZZ50_RS09780	COG0305	Participates in initiation and elongation during chromosome replication
LZZ50_RS09785	COG0415	Belongs to the DNA photolyase family
LZZ50_RS09795	COG0583	DNA-binding transcription factor activity
LZZ50_RS09810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS09840	COG3706	GGDEF domain
LZZ50_RS09865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LZZ50_RS09880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZZ50_RS09890	COG0497	DNA recombination
LZZ50_RS09895	COG1420	regulation of RNA biosynthetic process
LZZ50_RS09900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LZZ50_RS09905	COG0443	Heat shock 70 kDa protein
LZZ50_RS09915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LZZ50_RS09920	COG0287	Prephenate dehydrogenase
LZZ50_RS09920	COG1605	Chorismate mutase
LZZ50_RS09940	COG2274	protein secretion by the type I secretion system
LZZ50_RS09945	COG0583	DNA-binding transcription factor activity
LZZ50_RS09950	COG1132	(ABC) transporter
LZZ50_RS09985	COG2850	peptidyl-arginine hydroxylation
LZZ50_RS10000	COG1253	flavin adenine dinucleotide binding
LZZ50_RS10030	COG1131	(ABC) transporter
LZZ50_RS10035	COG1725	Transcriptional regulator
LZZ50_RS10045	COG0386	Belongs to the glutathione peroxidase family
LZZ50_RS10060	COG2900	Belongs to the SlyX family
LZZ50_RS10090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZZ50_RS10100	COG1410	methionine synthase
LZZ50_RS10100	COG0646	methionine synthase
LZZ50_RS10105	COG0646	methionine synthase
LZZ50_RS10105	COG1410	methionine synthase
LZZ50_RS10110	COG2226	methyltransferase
LZZ50_RS10115	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS10130	COG0557	exoribonuclease II activity
LZZ50_RS10140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZZ50_RS10155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZZ50_RS10165	COG0704	Plays a role in the regulation of phosphate uptake
LZZ50_RS10170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZZ50_RS10175	COG0581	inorganic phosphate transmembrane transporter activity
LZZ50_RS10180	COG0573	inorganic phosphate transmembrane transporter activity
LZZ50_RS10185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZZ50_RS10210	COG0659	secondary active sulfate transmembrane transporter activity
LZZ50_RS10215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZZ50_RS10225	COG1024	Enoyl-CoA hydratase
LZZ50_RS10235	COG0494	nUDIX hydrolase
LZZ50_RS10270	COG2264	protein methyltransferase activity
LZZ50_RS10275	COG0488	(ABC) transporter
LZZ50_RS10290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LZZ50_RS10300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LZZ50_RS10315	COG2925	Exonuclease
LZZ50_RS10320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZZ50_RS10325	COG3844	kynureninase activity
LZZ50_RS10335	COG0662	Cupin 2, conserved barrel domain protein
LZZ50_RS10340	COG0288	reversible hydration of carbon dioxide
LZZ50_RS10385	COG2808	Putative FMN-binding domain
LZZ50_RS10405	COG0017	Asparaginyl-tRNA synthetase
LZZ50_RS10410	COG0316	Belongs to the HesB IscA family
LZZ50_RS10435	COG3115	cell septum assembly
LZZ50_RS10445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZZ50_RS10450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LZZ50_RS10455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZZ50_RS10465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LZZ50_RS10475	COG4993	Dehydrogenase
LZZ50_RS10490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LZZ50_RS10500	COG2986	histidine ammonia-lyase
LZZ50_RS10505	COG1228	amidohydrolase
LZZ50_RS10540	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LZZ50_RS10545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LZZ50_RS10550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZZ50_RS10555	COG1605	Chorismate mutase
LZZ50_RS10555	COG0077	Prephenate dehydratase
LZZ50_RS10560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LZZ50_RS10575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LZZ50_RS10580	COG0583	DNA-binding transcription factor activity
LZZ50_RS10605	COG0840	transmembrane signaling receptor activity
LZZ50_RS10630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LZZ50_RS10645	COG0840	transmembrane signaling receptor activity
LZZ50_RS10665	COG0784	Response regulator, receiver
LZZ50_RS10665	COG4191	Histidine kinase
LZZ50_RS10670	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LZZ50_RS10675	COG0784	Response regulator, receiver
LZZ50_RS10675	COG4191	Histidine kinase
LZZ50_RS10690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZZ50_RS10710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZZ50_RS10715	COG1404	Belongs to the peptidase S8 family
LZZ50_RS10725	COG1595	DNA-templated transcription, initiation
LZZ50_RS10775	COG2244	polysaccharide biosynthetic process
LZZ50_RS10805	COG2264	protein methyltransferase activity
LZZ50_RS10810	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS10815	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS10830	COG1136	(ABC) transporter
LZZ50_RS10835	COG1132	(ABC) transporter
LZZ50_RS10840	COG0477	Major facilitator Superfamily
LZZ50_RS10845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZZ50_RS10860	COG1253	flavin adenine dinucleotide binding
LZZ50_RS10910	COG0148	phosphopyruvate hydratase activity
LZZ50_RS10920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LZZ50_RS10925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LZZ50_RS10935	COG2840	Smr protein MutS2
LZZ50_RS10940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LZZ50_RS10945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZZ50_RS10950	COG1238	metal cluster binding
LZZ50_RS10965	COG1534	Rna-binding protein
LZZ50_RS10970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LZZ50_RS10980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZZ50_RS10995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZZ50_RS11000	COG1546	Belongs to the CinA family
LZZ50_RS11005	COG4771	TonB-dependent receptor
LZZ50_RS11020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LZZ50_RS11025	COG2137	regulation of response to DNA damage stimulus
LZZ50_RS11030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZZ50_RS11035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LZZ50_RS11050	COG1741	Belongs to the pirin family
LZZ50_RS11055	COG0583	DNA-binding transcription factor activity
LZZ50_RS11080	COG0352	thiamine-phosphate diphosphorylase activity
LZZ50_RS11080	COG0351	phosphomethylpyrimidine kinase
LZZ50_RS11095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LZZ50_RS11100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZZ50_RS11115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZZ50_RS11125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZZ50_RS11130	COG3734	2-keto-3-deoxy-galactonokinase
LZZ50_RS11140	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS11145	COG0800	Aldolase
LZZ50_RS11180	COG1501	Belongs to the glycosyl hydrolase 31 family
LZZ50_RS11190	COG1070	Carbohydrate kinase
LZZ50_RS11195	COG2115	Belongs to the xylose isomerase family
LZZ50_RS11200	COG0477	Major facilitator Superfamily
LZZ50_RS11220	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZZ50_RS11245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LZZ50_RS11250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LZZ50_RS11280	COG1472	Belongs to the glycosyl hydrolase 3 family
LZZ50_RS11290	COG4251	negative regulation of phosphorylation
LZZ50_RS11290	COG5001	Diguanylate cyclase
LZZ50_RS11290	COG3706	GGDEF domain
LZZ50_RS11290	COG2203	Gaf domain
LZZ50_RS11295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZZ50_RS11300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZZ50_RS11310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZZ50_RS11315	COG0671	phosphoesterase, PA-phosphatase related
LZZ50_RS11325	COG1794	racemase activity, acting on amino acids and derivatives
LZZ50_RS11335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LZZ50_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
LZZ50_RS11380	COG1215	transferase activity, transferring glycosyl groups
LZZ50_RS11385	COG0726	polysaccharide deacetylase
LZZ50_RS11385	COG1649	PFAM Uncharacterised BCR, COG1649
LZZ50_RS11395	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LZZ50_RS11400	COG0527	aspartate kinase activity
LZZ50_RS11400	COG0460	homoserine dehydrogenase
LZZ50_RS11405	COG0083	homoserine kinase activity
LZZ50_RS11425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZZ50_RS11450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZZ50_RS11455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZZ50_RS11460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LZZ50_RS11460	COG0131	Imidazoleglycerol-phosphate dehydratase
LZZ50_RS11465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LZZ50_RS11470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LZZ50_RS11475	COG0107	imidazoleglycerol-phosphate synthase activity
LZZ50_RS11480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LZZ50_RS11480	COG0140	phosphoribosyl-ATP diphosphatase activity
LZZ50_RS11510	COG0531	amino acid
LZZ50_RS11515	COG0531	amino acid
LZZ50_RS11525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZZ50_RS11530	COG0277	FAD linked oxidase domain protein
LZZ50_RS11550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZZ50_RS11590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZZ50_RS11595	COG2258	MOSC domain
LZZ50_RS11605	COG0505	Belongs to the CarA family
LZZ50_RS11615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LZZ50_RS11620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZZ50_RS11630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZZ50_RS11645	COG3279	Response regulator of the LytR AlgR family
LZZ50_RS11655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LZZ50_RS11665	COG0784	Response regulator, receiver
LZZ50_RS11665	COG2198	Histidine kinase
LZZ50_RS11665	COG2205	protein histidine kinase activity
LZZ50_RS11670	COG1024	Enoyl-CoA hydratase
LZZ50_RS11675	COG0318	PFAM AMP-dependent synthetase and ligase
LZZ50_RS11705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZZ50_RS11730	COG0840	transmembrane signaling receptor activity
LZZ50_RS11740	COG0835	chemotaxis
LZZ50_RS11755	COG0840	transmembrane signaling receptor activity
LZZ50_RS11760	COG0840	transmembrane signaling receptor activity
LZZ50_RS11765	COG0840	transmembrane signaling receptor activity
LZZ50_RS11770	COG0840	transmembrane signaling receptor activity
LZZ50_RS11780	COG0840	transmembrane signaling receptor activity
LZZ50_RS11800	COG0840	transmembrane signaling receptor activity
LZZ50_RS11810	COG0840	transmembrane signaling receptor activity
LZZ50_RS11825	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS11835	COG0835	chemotaxis
LZZ50_RS11845	COG1360	Flagellar Motor Protein
LZZ50_RS11850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LZZ50_RS11890	COG0643	Histidine kinase
LZZ50_RS11890	COG2198	Histidine kinase
LZZ50_RS11890	COG0784	Response regulator, receiver
LZZ50_RS11940	COG3300	MHYT domain
LZZ50_RS11940	COG5001	Diguanylate cyclase
LZZ50_RS11945	COG1684	flagellar biosynthetic protein fliR
LZZ50_RS11960	COG3190	flagellar
LZZ50_RS12010	COG1677	Flagellar hook-basal body complex protein FliE
LZZ50_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS12060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZZ50_RS12080	COG2201	protein-glutamate methylesterase activity
LZZ50_RS12110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LZZ50_RS12115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZZ50_RS12130	COG1705	Flagellar rod assembly protein muramidase FlgJ
LZZ50_RS12130	COG3951	Flagellar rod assembly protein muramidase FlgJ
LZZ50_RS12135	COG1706	bacterial-type flagellum-dependent cell motility
LZZ50_RS12140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LZZ50_RS12150	COG4787	bacterial-type flagellum-dependent cell motility
LZZ50_RS12160	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LZZ50_RS12165	COG1558	bacterial-type flagellum-dependent cell motility
LZZ50_RS12170	COG1815	bacterial-type flagellum-dependent cell motility
LZZ50_RS12175	COG0784	Response regulator, receiver
LZZ50_RS12175	COG0835	chemotaxis
LZZ50_RS12195	COG4191	Histidine kinase
LZZ50_RS12230	COG0482	sulfurtransferase activity
LZZ50_RS12250	COG0542	response to heat
LZZ50_RS12260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LZZ50_RS12270	COG0492	ferredoxin-NADP+ reductase activity
LZZ50_RS12275	COG1674	ftsk spoiiie
LZZ50_RS12290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZZ50_RS12295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LZZ50_RS12300	COG0183	Belongs to the thiolase family
LZZ50_RS12305	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZZ50_RS12305	COG1024	Enoyl-CoA hydratase
LZZ50_RS12320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LZZ50_RS12330	COG1426	Protein conserved in bacteria
LZZ50_RS12340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZZ50_RS12345	COG1160	GTP binding
LZZ50_RS12350	COG0303	'Molybdopterin
LZZ50_RS12355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZZ50_RS12380	COG0708	Exodeoxyribonuclease III
LZZ50_RS12390	COG0303	'Molybdopterin
LZZ50_RS12395	COG0746	molybdenum cofactor guanylyltransferase activity
LZZ50_RS12405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZZ50_RS12405	COG1648	precorrin-2 dehydrogenase activity
LZZ50_RS12415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LZZ50_RS12420	COG2223	nitrite transmembrane transporter activity
LZZ50_RS12425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZZ50_RS12435	COG0243	molybdopterin cofactor binding
LZZ50_RS12455	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LZZ50_RS12465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZZ50_RS12495	COG5001	Diguanylate cyclase
LZZ50_RS12545	COG4191	Histidine kinase
LZZ50_RS12545	COG0784	Response regulator, receiver
LZZ50_RS12605	COG0840	transmembrane signaling receptor activity
LZZ50_RS12640	COG3781	membrane
LZZ50_RS12650	COG2197	response regulator
LZZ50_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS12770	COG0428	transporter
LZZ50_RS12780	COG1530	ribonuclease E activity
LZZ50_RS12790	COG1054	Belongs to the UPF0176 family
LZZ50_RS12810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZZ50_RS12835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZZ50_RS12840	COG0322	excinuclease ABC activity
LZZ50_RS12850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZZ50_RS12855	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LZZ50_RS12860	COG1663	tetraacyldisaccharide 4'-kinase activity
LZZ50_RS12865	COG1132	(ABC) transporter
LZZ50_RS12870	COG0848	biopolymer transport protein
LZZ50_RS12875	COG0811	peptide transport
LZZ50_RS12890	COG1136	(ABC) transporter
LZZ50_RS12895	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZZ50_RS12905	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LZZ50_RS12910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZZ50_RS12925	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZZ50_RS12950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZZ50_RS12955	COG0837	glucose binding
LZZ50_RS12965	COG0129	dihydroxy-acid dehydratase activity
LZZ50_RS12970	COG0800	Aldolase
LZZ50_RS13035	COG0784	Response regulator, receiver
LZZ50_RS13035	COG2205	protein histidine kinase activity
LZZ50_RS13035	COG5002	protein histidine kinase activity
LZZ50_RS13040	COG2183	response to ionizing radiation
LZZ50_RS13050	COG0723	plastoquinol--plastocyanin reductase activity
LZZ50_RS13050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZZ50_RS13065	COG3243	poly(R)-hydroxyalkanoic acid synthase
LZZ50_RS13075	COG1183	phosphatidylcholine synthase activity
LZZ50_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS13105	COG0668	transmembrane transport
LZZ50_RS13110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LZZ50_RS13125	COG1914	H( )-stimulated, divalent metal cation uptake system
LZZ50_RS13135	COG2814	Major facilitator Superfamily
LZZ50_RS13150	COG1335	isochorismatase
LZZ50_RS13165	COG2197	response regulator
LZZ50_RS13185	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS13200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZZ50_RS13210	COG0475	glutathione-regulated potassium exporter activity
LZZ50_RS13210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZZ50_RS13215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZZ50_RS13230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZZ50_RS13245	COG0539	negative regulation of cytoplasmic translation
LZZ50_RS13250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LZZ50_RS13265	COG2957	Belongs to the agmatine deiminase family
LZZ50_RS13270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZZ50_RS13295	COG0395	ABC-type sugar transport system, permease component
LZZ50_RS13300	COG1175	transmembrane transport
LZZ50_RS13305	COG1653	transport
LZZ50_RS13320	COG1609	Transcriptional regulator
LZZ50_RS13330	COG2350	Protein conserved in bacteria
LZZ50_RS13335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LZZ50_RS13340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LZZ50_RS13345	COG1187	pseudouridine synthase activity
LZZ50_RS13365	COG0436	Aminotransferase
LZZ50_RS13370	COG4133	protoheme IX ABC transporter activity
LZZ50_RS13390	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZZ50_RS13415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZZ50_RS13425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LZZ50_RS13430	COG4988	ABC transporter
LZZ50_RS13440	COG1294	oxidase, subunit
LZZ50_RS13485	COG0165	Argininosuccinate lyase
LZZ50_RS13500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZZ50_RS13505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZZ50_RS13510	COG0137	argininosuccinate synthase activity
LZZ50_RS13515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LZZ50_RS13530	COG2166	iron-sulfur cluster assembly
LZZ50_RS13550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZZ50_RS13565	COG4303	Ethanolamine ammonia lyase large subunit
LZZ50_RS13570	COG4302	ethanolamine ammonia-lyase activity
LZZ50_RS13585	COG4677	pectinesterase activity
LZZ50_RS13610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZZ50_RS13615	COG0402	S-adenosylhomocysteine deaminase activity
LZZ50_RS13625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZZ50_RS13635	COG5001	Diguanylate cyclase
LZZ50_RS13635	COG3300	MHYT domain
LZZ50_RS13650	COG0483	inositol monophosphate 1-phosphatase activity
LZZ50_RS13655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZZ50_RS13670	COG0488	(ABC) transporter
LZZ50_RS13675	COG0513	Belongs to the DEAD box helicase family
LZZ50_RS13680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LZZ50_RS13685	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LZZ50_RS13695	COG0625	glutathione transferase activity
LZZ50_RS13710	COG4681	YaeQ
LZZ50_RS13715	COG2081	HI0933 family
LZZ50_RS13730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZZ50_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS13755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LZZ50_RS13760	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZZ50_RS13770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZZ50_RS13770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZZ50_RS13775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZZ50_RS13790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LZZ50_RS13820	COG0835	chemotaxis
LZZ50_RS13825	COG0840	transmembrane signaling receptor activity
LZZ50_RS13830	COG2094	Belongs to the DNA glycosylase MPG family
LZZ50_RS13835	COG1201	RNA secondary structure unwinding
LZZ50_RS13845	COG2969	positive regulation of protein catabolic process
LZZ50_RS13850	COG0625	glutathione transferase activity
LZZ50_RS13855	COG2857	Cytochrome c1
LZZ50_RS13860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZZ50_RS13865	COG0723	plastoquinol--plastocyanin reductase activity
LZZ50_RS13870	COG0741	lytic transglycosylase activity
LZZ50_RS13885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LZZ50_RS13890	COG1702	phosphate starvation-inducible protein PhoH
LZZ50_RS13910	COG4535	Mg2 and Co2 transporter CorC
LZZ50_RS13925	COG1012	belongs to the aldehyde dehydrogenase family
LZZ50_RS13935	COG1177	transmembrane transport
LZZ50_RS13940	COG1176	ABC-type spermidine putrescine transport system, permease component I
LZZ50_RS13945	COG3842	ATPase activity
LZZ50_RS13965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZZ50_RS13980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LZZ50_RS13985	COG0174	glutamine synthetase
LZZ50_RS13990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZZ50_RS14000	COG2703	oxygen carrier activity
LZZ50_RS14005	COG0477	Major facilitator Superfamily
LZZ50_RS14015	COG0243	molybdopterin cofactor binding
LZZ50_RS14025	COG2223	nitrite transmembrane transporter activity
LZZ50_RS14030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LZZ50_RS14040	COG2733	membrane
LZZ50_RS14045	COG2205	protein histidine kinase activity
LZZ50_RS14045	COG5002	protein histidine kinase activity
LZZ50_RS14045	COG0784	Response regulator, receiver
LZZ50_RS14055	COG0477	Major facilitator Superfamily
LZZ50_RS14070	COG0300	oxidoreductase activity
LZZ50_RS14080	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS14090	COG0604	alcohol dehydrogenase
LZZ50_RS14090	COG3321	synthase
LZZ50_RS14095	COG2902	Dehydrogenase
LZZ50_RS14105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS14110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZZ50_RS14115	COG1609	Transcriptional regulator
LZZ50_RS14120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZZ50_RS14120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZZ50_RS14125	COG1105	Belongs to the carbohydrate kinase PfkB family
LZZ50_RS14130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZZ50_RS14130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZZ50_RS14165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZZ50_RS14175	COG1862	Preprotein translocase
LZZ50_RS14185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LZZ50_RS14225	COG3291	Pkd domain containing protein
LZZ50_RS14235	COG0644	oxidoreductase
LZZ50_RS14240	COG0688	phosphatidylethanolamine metabolic process
LZZ50_RS14250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZZ50_RS14270	COG0742	ribosomal rna small subunit methyltransferase
LZZ50_RS14275	COG0326	Molecular chaperone. Has ATPase activity
LZZ50_RS14345	COG0531	amino acid
LZZ50_RS14360	COG0006	proline dipeptidase activity
LZZ50_RS14370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZZ50_RS14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZZ50_RS14390	COG3938	Belongs to the proline racemase family
LZZ50_RS14400	COG0552	protein localization to endoplasmic reticulum
LZZ50_RS14410	COG1194	a g-specific adenine glycosylase
LZZ50_RS14420	COG0784	Response regulator, receiver
LZZ50_RS14420	COG4191	Histidine kinase
LZZ50_RS14430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZZ50_RS14460	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS14470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LZZ50_RS14490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZZ50_RS14495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZZ50_RS14500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZZ50_RS14525	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS14535	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS14540	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS14590	COG0072	phenylalanine-tRNA ligase activity
LZZ50_RS14590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZZ50_RS14595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LZZ50_RS14610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZZ50_RS14615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LZZ50_RS14630	COG2211	Major facilitator Superfamily
LZZ50_RS14630	COG2190	(PTS) system
LZZ50_RS14640	COG1082	Xylose isomerase domain protein TIM barrel
LZZ50_RS14650	COG0366	Alpha amylase catalytic
LZZ50_RS14660	COG3702	type iv secretory pathway
LZZ50_RS14680	COG2948	multi-organism process
LZZ50_RS14700	COG3505	Type IV secretory pathway VirD4
LZZ50_RS14715	COG0556	nucleotide-excision repair
LZZ50_RS14760	COG1611	Belongs to the LOG family
LZZ50_RS14770	COG2095	MarC family integral membrane protein
LZZ50_RS14775	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS14780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZZ50_RS14815	COG1185	polyribonucleotide nucleotidyltransferase activity
LZZ50_RS14820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LZZ50_RS14825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LZZ50_RS14830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LZZ50_RS14840	COG0195	Participates in both transcription termination and antitermination
LZZ50_RS14845	COG0779	Required for maturation of 30S ribosomal subunits
LZZ50_RS14855	COG1007	ATP synthesis coupled electron transport
LZZ50_RS14875	COG0839	Belongs to the complex I subunit 6 family
LZZ50_RS14880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZZ50_RS14885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LZZ50_RS14895	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZZ50_RS14900	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZZ50_RS14910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZZ50_RS14920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZZ50_RS14940	COG4221	oxidoreductase activity
LZZ50_RS14970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZZ50_RS14975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZZ50_RS14990	COG0133	tryptophan synthase activity
LZZ50_RS15005	COG0101	tRNA pseudouridine synthase activity
LZZ50_RS15020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZZ50_RS15025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZZ50_RS15040	COG2890	protein-(glutamine-N5) methyltransferase activity
LZZ50_RS15050	COG0688	phosphatidylethanolamine metabolic process
LZZ50_RS15060	COG0433	COG0433 Predicted ATPase
LZZ50_RS15070	COG0494	nUDIX hydrolase
LZZ50_RS15085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZZ50_RS15095	COG0412	Dienelactone hydrolase
LZZ50_RS15115	COG0717	Belongs to the dCTP deaminase family
LZZ50_RS15120	COG0489	protein tyrosine kinase activity
LZZ50_RS15145	COG3590	peptidase
LZZ50_RS15150	COG3590	peptidase
LZZ50_RS15175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZZ50_RS15180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZZ50_RS15185	COG2311	Membrane
LZZ50_RS15190	COG1047	Peptidyl-prolyl cis-trans
LZZ50_RS15195	COG0791	NLP P60 protein
LZZ50_RS15200	COG0791	NLP P60 protein
LZZ50_RS15230	COG0037	tRNA processing
LZZ50_RS15235	COG1722	exodeoxyribonuclease VII activity
LZZ50_RS15240	COG0142	geranyltranstransferase activity
LZZ50_RS15250	COG4104	PAAR repeat-containing protein
LZZ50_RS15260	COG0312	modulator of DNA gyrase
LZZ50_RS15270	COG0312	modulator of DNA gyrase
LZZ50_RS15280	COG3164	Protein of unknown function
LZZ50_RS15290	COG0424	maF-like protein
LZZ50_RS15295	COG2968	Membrane
LZZ50_RS15310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LZZ50_RS15330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LZZ50_RS15345	COG0495	leucyl-tRNA aminoacylation
LZZ50_RS15355	COG3118	belongs to the thioredoxin family
LZZ50_RS15365	COG2155	Conserved Protein
LZZ50_RS15405	COG1132	(ABC) transporter
LZZ50_RS15415	COG0475	glutathione-regulated potassium exporter activity
LZZ50_RS15425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZZ50_RS15445	COG1187	pseudouridine synthase activity
LZZ50_RS15450	COG5002	protein histidine kinase activity
LZZ50_RS15450	COG5001	Diguanylate cyclase
LZZ50_RS15560	COG1404	Belongs to the peptidase S8 family
LZZ50_RS15570	COG1404	Belongs to the peptidase S8 family
LZZ50_RS15585	COG0667	Aldo Keto reductase
LZZ50_RS15590	COG2814	Major facilitator Superfamily
LZZ50_RS15595	COG0583	DNA-binding transcription factor activity
LZZ50_RS15605	COG2207	Transcriptional regulator
LZZ50_RS15620	COG0667	Aldo Keto reductase
LZZ50_RS15625	COG1309	transcriptional regulator
LZZ50_RS15650	COG0735	belongs to the Fur family
LZZ50_RS15655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZZ50_RS15680	COG4452	Inner membrane protein CreD
LZZ50_RS15695	COG2205	protein histidine kinase activity
LZZ50_RS15700	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS15705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZZ50_RS15715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZZ50_RS15725	COG2198	Histidine kinase
LZZ50_RS15725	COG0643	Histidine kinase
LZZ50_RS15730	COG0840	transmembrane signaling receptor activity
LZZ50_RS15735	COG0835	chemotaxis
LZZ50_RS15740	COG2202	Pas domain
LZZ50_RS15740	COG2200	EAL domain
LZZ50_RS15740	COG2199	diguanylate cyclase activity
LZZ50_RS15745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZZ50_RS15755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZZ50_RS15760	COG3590	peptidase
LZZ50_RS15770	COG0588	phosphoglycerate mutase activity
LZZ50_RS15775	COG1515	deoxyribonuclease V activity
LZZ50_RS15780	COG1741	Belongs to the pirin family
LZZ50_RS15795	COG1741	Belongs to the pirin family
LZZ50_RS15800	COG1966	Carbon starvation protein
LZZ50_RS15805	COG2879	small protein
LZZ50_RS15810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZZ50_RS15850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LZZ50_RS15855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LZZ50_RS15860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LZZ50_RS15865	COG2080	2 iron, 2 sulfur cluster binding
LZZ50_RS15870	COG3321	synthase
LZZ50_RS15870	COG0604	alcohol dehydrogenase
LZZ50_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS15875	COG4251	negative regulation of phosphorylation
LZZ50_RS15875	COG5001	Diguanylate cyclase
LZZ50_RS15875	COG3706	GGDEF domain
LZZ50_RS15875	COG2203	Gaf domain
LZZ50_RS15880	COG0629	single-stranded DNA binding
LZZ50_RS15885	COG0142	geranyltranstransferase activity
LZZ50_RS15910	COG0527	aspartate kinase activity
LZZ50_RS15915	COG0384	phenazine biosynthesis protein PhzF
LZZ50_RS15920	COG0384	phenazine biosynthesis protein PhzF
LZZ50_RS15930	COG1764	response to oxidative stress
LZZ50_RS15940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LZZ50_RS15945	COG1678	Uncharacterized ACR, COG1678
LZZ50_RS15950	COG0519	Catalyzes the synthesis of GMP from XMP
LZZ50_RS15970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZZ50_RS15985	COG4942	peptidase
LZZ50_RS16005	COG0693	protein deglycase activity
LZZ50_RS16015	COG1959	2 iron, 2 sulfur cluster binding
LZZ50_RS16020	COG0719	Fe-S assembly protein
LZZ50_RS16025	COG0396	ATPase activity
LZZ50_RS16030	COG0719	Fe-S assembly protein
LZZ50_RS16035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZZ50_RS16045	COG2146	nitrite reductase [NAD(P)H] activity
LZZ50_RS16050	COG4774	siderophore transport
LZZ50_RS16055	COG3128	pkhd-type hydroxylase
LZZ50_RS16080	COG1477	protein flavinylation
LZZ50_RS16085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZZ50_RS16100	COG1555	photosystem II stabilization
LZZ50_RS16105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZZ50_RS16115	COG3178	'Phosphotransferase
LZZ50_RS16120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZZ50_RS16130	COG0628	permease
LZZ50_RS16150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZZ50_RS16175	COG0271	Belongs to the BolA IbaG family
LZZ50_RS16185	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZZ50_RS16195	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LZZ50_RS16200	COG1137	ATPase activity
LZZ50_RS16215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZZ50_RS16235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZZ50_RS16240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZZ50_RS16245	COG2239	Acts as a magnesium transporter
LZZ50_RS16255	COG1294	oxidase, subunit
LZZ50_RS16260	COG1271	oxidase subunit
LZZ50_RS16280	COG1113	amino acid transport
LZZ50_RS16295	COG2197	response regulator
LZZ50_RS16300	COG0531	amino acid
LZZ50_RS16350	COG2814	Major facilitator Superfamily
LZZ50_RS16355	COG0754	glutathionylspermidine amidase activity
LZZ50_RS16380	COG1842	Phage shock protein A
LZZ50_RS16400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LZZ50_RS16405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LZZ50_RS16415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LZZ50_RS16420	COG0477	Major facilitator Superfamily
LZZ50_RS16430	COG0784	Response regulator, receiver
LZZ50_RS16430	COG2198	Histidine kinase
LZZ50_RS16430	COG2205	protein histidine kinase activity
LZZ50_RS16435	COG2353	YceI-like domain
LZZ50_RS16440	COG3038	cytochrome b561
LZZ50_RS16450	COG1278	Cold shock
LZZ50_RS16460	COG1760	l-serine dehydratase
LZZ50_RS16470	COG0527	aspartate kinase activity
LZZ50_RS16470	COG0460	homoserine dehydrogenase
LZZ50_RS16475	COG0626	cystathionine gamma-synthase activity
LZZ50_RS16480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZZ50_RS16490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LZZ50_RS16495	COG1272	protein, Hemolysin III
LZZ50_RS16500	COG2982	Protein involved in outer membrane biogenesis
LZZ50_RS16505	COG0516	GMP reductase activity
LZZ50_RS16505	COG0517	IMP dehydrogenase activity
LZZ50_RS16510	COG0463	Glycosyl transferase, family 2
LZZ50_RS16515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZZ50_RS16520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZZ50_RS16535	COG1309	transcriptional regulator
LZZ50_RS16545	COG1960	acyl-CoA dehydrogenase activity
LZZ50_RS16575	COG0509	glycine decarboxylation via glycine cleavage system
LZZ50_RS16580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LZZ50_RS16590	COG0330	HflC and HflK could
LZZ50_RS16595	COG1742	UPF0060 membrane protein
LZZ50_RS16610	COG0494	nUDIX hydrolase
LZZ50_RS16620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZZ50_RS16625	COG0837	glucose binding
LZZ50_RS16650	COG1388	LysM domain
LZZ50_RS16650	COG3858	chitin binding
LZZ50_RS16655	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZZ50_RS16665	COG1472	Belongs to the glycosyl hydrolase 3 family
LZZ50_RS16680	COG0531	amino acid
LZZ50_RS16690	COG1486	melibiose metabolic process
LZZ50_RS16700	COG3537	Alpha-1,2-mannosidase
LZZ50_RS16735	COG1446	asparaginase
LZZ50_RS16745	COG2304	oxidoreductase activity
LZZ50_RS16750	COG1595	DNA-templated transcription, initiation
LZZ50_RS16775	COG2198	Histidine kinase
LZZ50_RS16775	COG0643	Histidine kinase
LZZ50_RS16775	COG0784	Response regulator, receiver
LZZ50_RS16780	COG0840	transmembrane signaling receptor activity
LZZ50_RS16785	COG0835	chemotaxis
LZZ50_RS16800	COG0189	ligase activity
LZZ50_RS16810	COG1397	ADP-ribosylglycohydrolase
LZZ50_RS16820	COG1199	ATP-dependent helicase activity
LZZ50_RS16830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZZ50_RS16835	COG1215	transferase activity, transferring glycosyl groups
LZZ50_RS16845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZZ50_RS16855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LZZ50_RS16860	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LZZ50_RS16870	COG0535	radical SAM domain protein
LZZ50_RS16885	COG0837	glucose binding
LZZ50_RS16895	COG1643	Atp-dependent helicase
LZZ50_RS16900	COG0783	Belongs to the Dps family
LZZ50_RS16905	COG0514	ATP-dependent DNA helicase (RecQ)
LZZ50_RS16920	COG1187	pseudouridine synthase activity
LZZ50_RS16930	COG0840	transmembrane signaling receptor activity
LZZ50_RS16955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LZZ50_RS16970	COG0667	Aldo Keto reductase
LZZ50_RS16975	COG0602	queuosine metabolic process
LZZ50_RS16985	COG2885	chlorophyll binding
LZZ50_RS16990	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS17000	COG0848	biopolymer transport protein
LZZ50_RS17010	COG0824	Thioesterase
LZZ50_RS17015	COG2255	four-way junction helicase activity
LZZ50_RS17070	COG0477	Major facilitator Superfamily
LZZ50_RS17100	COG2951	lytic endotransglycosylase activity
LZZ50_RS17105	COG0488	(ABC) transporter
LZZ50_RS17135	COG4651	solute:proton antiporter activity
LZZ50_RS17135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZZ50_RS17145	COG4772	TonB-dependent receptor
LZZ50_RS17155	COG4264	IucA IucC family
LZZ50_RS17165	COG4264	IucA IucC family
LZZ50_RS17170	COG0019	diaminopimelate decarboxylase activity
LZZ50_RS17185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LZZ50_RS17195	COG4206	TonB-dependent receptor
LZZ50_RS17205	COG0542	response to heat
LZZ50_RS17210	COG1116	anion transmembrane transporter activity
LZZ50_RS17215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LZZ50_RS17220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LZZ50_RS17225	COG0667	Aldo Keto reductase
LZZ50_RS17230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZZ50_RS17235	COG4771	TonB-dependent receptor
LZZ50_RS17275	COG4771	TonB-dependent receptor
LZZ50_RS17280	COG1877	trehalose-phosphatase activity
LZZ50_RS17285	COG3387	PFAM Glycoside hydrolase 15-related
LZZ50_RS17300	COG0840	transmembrane signaling receptor activity
LZZ50_RS17305	COG3011	Protein conserved in bacteria
LZZ50_RS17315	COG1496	oxidoreductase activity
LZZ50_RS17320	COG0564	pseudouridine synthase activity
LZZ50_RS17325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZZ50_RS17335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZZ50_RS17335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZZ50_RS17360	COG0045	succinate-CoA ligase (ADP-forming) activity
LZZ50_RS17390	COG2194	sulfuric ester hydrolase activity
LZZ50_RS17395	COG4969	Belongs to the N-Me-Phe pilin family
LZZ50_RS17405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZZ50_RS17425	COG0745	RESPONSE REGULATOR receiver
LZZ50_RS17435	COG0189	ligase activity
LZZ50_RS17480	COG3273	potassium ion transport
LZZ50_RS17480	COG0471	metal ion transport
LZZ50_RS17500	COG1970	mechanosensitive ion channel activity
LZZ50_RS17510	COG1609	Transcriptional regulator
LZZ50_RS17520	COG3250	beta-galactosidase activity
LZZ50_RS17525	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS17535	COG2272	Belongs to the type-B carboxylesterase lipase family
LZZ50_RS17540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZZ50_RS17565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZZ50_RS17570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS17575	COG2895	sulfate adenylyltransferase (ATP) activity
LZZ50_RS17575	COG0529	Catalyzes the synthesis of activated sulfate
LZZ50_RS17585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZZ50_RS17590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZZ50_RS17595	COG0175	sulfate reduction
LZZ50_RS17615	COG0784	Response regulator, receiver
LZZ50_RS17615	COG2198	Histidine kinase
LZZ50_RS17615	COG2205	protein histidine kinase activity
LZZ50_RS17630	COG1648	precorrin-2 dehydrogenase activity
LZZ50_RS17630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZZ50_RS17645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LZZ50_RS17650	COG3588	fructose-bisphosphate aldolase
LZZ50_RS17655	COG0469	pyruvate kinase activity
LZZ50_RS17685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZZ50_RS17695	COG3047	cAMP biosynthetic process
LZZ50_RS17700	COG3047	cAMP biosynthetic process
LZZ50_RS17710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZZ50_RS17710	COG3453	Protein conserved in bacteria
LZZ50_RS17715	COG0725	ABC transporter, periplasmic molybdate-binding protein
LZZ50_RS17720	COG4149	molybdate abc transporter
LZZ50_RS17770	COG1376	ErfK ybiS ycfS ynhG family protein
LZZ50_RS17775	COG0739	heme binding
LZZ50_RS17780	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS17785	COG0583	DNA-binding transcription factor activity
LZZ50_RS17790	COG4773	Receptor
LZZ50_RS17800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZZ50_RS17805	COG1301	dicarboxylic acid transport
LZZ50_RS17835	COG0714	Associated with various cellular activities
LZZ50_RS17865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LZZ50_RS17890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZZ50_RS17900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZZ50_RS17915	COG1561	YicC-like family, N-terminal region
LZZ50_RS17920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LZZ50_RS17935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZZ50_RS17950	COG0006	proline dipeptidase activity
LZZ50_RS17960	COG0006	proline dipeptidase activity
LZZ50_RS17985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZZ50_RS18005	COG2912	Transglutaminase-like superfamily
LZZ50_RS18015	COG1773	rubredoxin
LZZ50_RS18020	COG0352	thiamine-phosphate diphosphorylase activity
LZZ50_RS18035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LZZ50_RS18045	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZZ50_RS18050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZZ50_RS18080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZZ50_RS18085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZZ50_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS18110	COG0671	phosphoesterase, PA-phosphatase related
LZZ50_RS18115	COG3781	membrane
LZZ50_RS18125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZZ50_RS18130	COG0563	adenylate kinase activity
LZZ50_RS18220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LZZ50_RS18230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZZ50_RS18250	COG3710	Transcriptional regulator
LZZ50_RS18255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LZZ50_RS18265	COG0823	Involved in the tonB-independent uptake of proteins
LZZ50_RS18265	COG1506	peptidase
LZZ50_RS18265	COG4946	Tricorn protease homolog
LZZ50_RS18270	COG0840	transmembrane signaling receptor activity
LZZ50_RS18275	COG0405	Gamma-glutamyltransferase
LZZ50_RS18280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LZZ50_RS18300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LZZ50_RS18305	COG0473	3-isopropylmalate dehydrogenase activity
LZZ50_RS18310	COG2226	methyltransferase
LZZ50_RS18315	COG0066	3-isopropylmalate dehydratase activity
LZZ50_RS18320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LZZ50_RS18340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZZ50_RS18345	COG1538	Outer membrane efflux protein
LZZ50_RS18350	COG1519	Transferase
LZZ50_RS18355	COG1560	Kdo2-lipid A biosynthetic process
LZZ50_RS18380	COG0280	phosphate acetyltransferase
LZZ50_RS18380	COG0281	malic enzyme
LZZ50_RS18395	COG4191	Histidine kinase
LZZ50_RS18410	COG0583	DNA-binding transcription factor activity
LZZ50_RS18425	COG0667	Aldo Keto reductase
LZZ50_RS18430	COG2197	response regulator
LZZ50_RS18440	COG0642	Histidine kinase
LZZ50_RS18455	COG2851	Citrate transporter
LZZ50_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS18465	COG1609	Transcriptional regulator
LZZ50_RS18470	COG2211	Major facilitator Superfamily
LZZ50_RS18545	COG4773	Receptor
LZZ50_RS18550	COG0726	polysaccharide deacetylase
LZZ50_RS18555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZZ50_RS18570	COG3964	amidohydrolase
LZZ50_RS18575	COG1228	amidohydrolase
LZZ50_RS18610	COG1307	EDD domain protein, DegV family
LZZ50_RS18620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZZ50_RS18625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZZ50_RS18650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZZ50_RS18650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZZ50_RS18665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LZZ50_RS18675	COG0488	(ABC) transporter
LZZ50_RS18680	COG0242	peptide deformylase activity
LZZ50_RS18700	COG0457	Tetratricopeptide repeat
LZZ50_RS18705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LZZ50_RS18710	COG1215	transferase activity, transferring glycosyl groups
LZZ50_RS18715	COG1215	transferase activity, transferring glycosyl groups
LZZ50_RS18775	COG2188	Transcriptional regulator
LZZ50_RS18785	COG1450	Type ii and iii secretion system protein
LZZ50_RS18800	COG3166	PFAM Fimbrial assembly family protein
LZZ50_RS18805	COG3156	type II secretion system protein K
LZZ50_RS18810	COG4795	General secretion pathway protein
LZZ50_RS18815	COG2165	general secretion pathway protein
LZZ50_RS18820	COG4970	Tfp pilus assembly protein FimT
LZZ50_RS18825	COG2165	general secretion pathway protein
LZZ50_RS18830	COG1459	type II secretion system
LZZ50_RS18835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZZ50_RS18840	COG1404	Belongs to the peptidase S8 family
LZZ50_RS18845	COG5295	Hep Hag repeat protein
LZZ50_RS18850	COG1404	Belongs to the peptidase S8 family
LZZ50_RS18855	COG5295	Hep Hag repeat protein
LZZ50_RS18860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LZZ50_RS18860	COG0047	phosphoribosylformylglycinamidine synthase activity
LZZ50_RS18865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZZ50_RS18870	COG4974	Belongs to the 'phage' integrase family
LZZ50_RS18880	COG0795	lipopolysaccharide-transporting ATPase activity
LZZ50_RS18900	COG0525	valine-tRNA ligase activity
LZZ50_RS18925	COG1183	phosphatidylcholine synthase activity
LZZ50_RS18935	COG0442	prolyl-tRNA aminoacylation
LZZ50_RS18950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZZ50_RS18955	COG1127	ABC transporter
LZZ50_RS18960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZZ50_RS18960	COG3218	ABC-type transport auxiliary lipoprotein component
LZZ50_RS18990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LZZ50_RS18995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZZ50_RS19000	COG0662	Cupin 2, conserved barrel domain protein
LZZ50_RS19000	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LZZ50_RS19025	COG2086	electron transfer activity
LZZ50_RS19040	COG0463	Glycosyl transferase, family 2
LZZ50_RS19055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZZ50_RS19060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZZ50_RS19075	COG0438	transferase activity, transferring glycosyl groups
LZZ50_RS19100	COG0626	cystathionine gamma-synthase activity
LZZ50_RS19130	COG0625	glutathione transferase activity
LZZ50_RS19140	COG0513	Belongs to the DEAD box helicase family
LZZ50_RS19150	COG4771	TonB-dependent receptor
LZZ50_RS19155	COG0720	synthase
LZZ50_RS19165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LZZ50_RS19170	COG1956	GAF domain-containing protein
LZZ50_RS19180	COG2819	hydrolase of the alpha beta superfamily
LZZ50_RS19190	COG0546	phosphoglycolate phosphatase activity
LZZ50_RS19195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZZ50_RS19210	COG0339	signal peptide processing
LZZ50_RS19225	COG2132	Multicopper oxidase
LZZ50_RS19255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZZ50_RS19260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZZ50_RS19265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZZ50_RS19270	COG1136	(ABC) transporter
LZZ50_RS19280	COG0577	efflux transmembrane transporter activity
LZZ50_RS19280	COG1136	(ABC) transporter
LZZ50_RS19290	COG4191	Histidine kinase
LZZ50_RS19300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZZ50_RS19315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LZZ50_RS19335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LZZ50_RS19340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LZZ50_RS19350	COG0356	it plays a direct role in the translocation of protons across the membrane
LZZ50_RS19365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LZZ50_RS19370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZZ50_RS19380	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZZ50_RS19415	COG2011	ABC-type metal ion transport system permease component
LZZ50_RS19420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LZZ50_RS19425	COG0697	spore germination
LZZ50_RS19430	COG1666	GTP binding
LZZ50_RS19440	COG5002	protein histidine kinase activity
LZZ50_RS19440	COG2198	Histidine kinase
LZZ50_RS19440	COG0784	Response regulator, receiver
LZZ50_RS19460	COG1187	pseudouridine synthase activity
LZZ50_RS19485	COG2205	protein histidine kinase activity
LZZ50_RS19485	COG2202	Pas domain
LZZ50_RS19505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LZZ50_RS19510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZZ50_RS19560	COG0842	Transport permease protein
LZZ50_RS19565	COG1131	(ABC) transporter
LZZ50_RS19570	COG0025	NhaP-type Na H and K H
LZZ50_RS19580	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LZZ50_RS19585	COG1573	uracil-dna glycosylase
LZZ50_RS19595	COG3384	dioxygenase
LZZ50_RS19605	COG0583	DNA-binding transcription factor activity
LZZ50_RS19615	COG0667	Aldo Keto reductase
LZZ50_RS19625	COG3590	peptidase
LZZ50_RS19640	COG0531	amino acid
LZZ50_RS19655	COG2972	Histidine kinase
LZZ50_RS19670	COG3685	Protein conserved in bacteria
LZZ50_RS19675	COG3546	catalase activity
LZZ50_RS19700	COG2204	response regulator
LZZ50_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS19715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LZZ50_RS19735	COG1132	(ABC) transporter
LZZ50_RS19745	COG1063	alcohol dehydrogenase
LZZ50_RS19770	COG0583	DNA-binding transcription factor activity
LZZ50_RS19775	COG2814	Major facilitator Superfamily
LZZ50_RS19815	COG1131	(ABC) transporter
LZZ50_RS19830	COG0251	oxidation-reduction process
LZZ50_RS19845	COG0840	transmembrane signaling receptor activity
LZZ50_RS19875	COG0659	secondary active sulfate transmembrane transporter activity
LZZ50_RS19880	COG0038	chloride channel
LZZ50_RS19885	COG0024	Methionine aminopeptidase
LZZ50_RS19900	COG1309	transcriptional regulator
LZZ50_RS19905	COG0583	DNA-binding transcription factor activity
LZZ50_RS19910	COG1902	pentaerythritol trinitrate reductase activity
LZZ50_RS19965	COG0300	oxidoreductase activity
LZZ50_RS19980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZZ50_RS19995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZZ50_RS20000	COG1490	D-aminoacyl-tRNA deacylase activity
LZZ50_RS20005	COG1560	Kdo2-lipid A biosynthetic process
LZZ50_RS20015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZZ50_RS20050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZZ50_RS20050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZZ50_RS20060	COG0242	peptide deformylase activity
LZZ50_RS20065	COG1652	LysM domain
LZZ50_RS20070	COG0758	DNA mediated transformation
LZZ50_RS20090	COG1754	DNA topoisomerase type I activity
LZZ50_RS20090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZZ50_RS20095	COG0009	L-threonylcarbamoyladenylate synthase
LZZ50_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
LZZ50_RS20120	COG0616	signal peptide processing
LZZ50_RS20125	COG0534	Mate efflux family protein
LZZ50_RS20140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZZ50_RS20145	COG0625	glutathione transferase activity
LZZ50_RS20160	COG1252	NADH dehydrogenase
LZZ50_RS20165	COG2860	membrane
LZZ50_RS20170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZZ50_RS20175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LZZ50_RS20180	COG2201	protein-glutamate methylesterase activity
LZZ50_RS20185	COG2177	Part of the ABC transporter FtsEX involved in
LZZ50_RS20190	COG2884	Cell division ATP-binding protein ftsE
LZZ50_RS20195	COG0513	Belongs to the DEAD box helicase family
LZZ50_RS20200	COG3118	belongs to the thioredoxin family
LZZ50_RS20205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZZ50_RS20210	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LZZ50_RS20230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZZ50_RS20230	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZZ50_RS20235	COG1473	amidohydrolase
LZZ50_RS20245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZZ50_RS20255	COG5383	Protein conserved in bacteria
LZZ50_RS20300	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LZZ50_RS20320	COG3023	N-Acetylmuramoyl-L-alanine amidase
LZZ50_RS20330	COG4948	Mandelate Racemase Muconate Lactonizing
LZZ50_RS20340	COG0531	amino acid
LZZ50_RS20355	COG4682	membrane
LZZ50_RS20360	COG2133	pyrroloquinoline quinone binding
LZZ50_RS20370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZZ50_RS20385	COG1610	YqeY-like protein
LZZ50_RS20390	COG1295	ribonuclease BN
LZZ50_RS20395	COG0358	DNA primase activity
LZZ50_RS20415	COG0109	protoheme IX farnesyltransferase activity
LZZ50_RS20445	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LZZ50_RS20460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor