locus-tag	class	description
K9U02_RS00045	COG0717	Belongs to the dCTP deaminase family
K9U02_RS00050	COG0489	protein tyrosine kinase activity
K9U02_RS00070	COG3590	peptidase
K9U02_RS00075	COG3590	peptidase
K9U02_RS00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9U02_RS00105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9U02_RS00110	COG2311	Membrane
K9U02_RS00115	COG1047	Peptidyl-prolyl cis-trans
K9U02_RS00120	COG0791	NLP P60 protein
K9U02_RS00125	COG0791	NLP P60 protein
K9U02_RS00140	COG1301	dicarboxylic acid transport
K9U02_RS00145	COG1785	Belongs to the alkaline phosphatase family
K9U02_RS00155	COG1722	exodeoxyribonuclease VII activity
K9U02_RS00160	COG0142	geranyltranstransferase activity
K9U02_RS00175	COG0312	modulator of DNA gyrase
K9U02_RS00185	COG0312	modulator of DNA gyrase
K9U02_RS00195	COG3164	Protein of unknown function
K9U02_RS00205	COG0424	maF-like protein
K9U02_RS00210	COG2968	Membrane
K9U02_RS00220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K9U02_RS00240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K9U02_RS00255	COG0495	leucyl-tRNA aminoacylation
K9U02_RS00265	COG3118	belongs to the thioredoxin family
K9U02_RS00290	COG2155	Conserved Protein
K9U02_RS00340	COG0475	glutathione-regulated potassium exporter activity
K9U02_RS00350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9U02_RS00370	COG1187	pseudouridine synthase activity
K9U02_RS00375	COG5001	Diguanylate cyclase
K9U02_RS00375	COG5002	protein histidine kinase activity
K9U02_RS00515	COG0667	Aldo Keto reductase
K9U02_RS00520	COG2814	Major facilitator Superfamily
K9U02_RS00525	COG0583	DNA-binding transcription factor activity
K9U02_RS00535	COG2207	Transcriptional regulator
K9U02_RS00560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9U02_RS00575	COG0735	belongs to the Fur family
K9U02_RS00580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9U02_RS00605	COG4452	Inner membrane protein CreD
K9U02_RS00625	COG2205	protein histidine kinase activity
K9U02_RS00630	COG0745	RESPONSE REGULATOR receiver
K9U02_RS00635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K9U02_RS00655	COG2198	Histidine kinase
K9U02_RS00655	COG0643	Histidine kinase
K9U02_RS00660	COG0840	transmembrane signaling receptor activity
K9U02_RS00665	COG0835	chemotaxis
K9U02_RS00670	COG2199	diguanylate cyclase activity
K9U02_RS00670	COG2200	EAL domain
K9U02_RS00670	COG2202	Pas domain
K9U02_RS00675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K9U02_RS00685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9U02_RS00690	COG3590	peptidase
K9U02_RS00700	COG0588	phosphoglycerate mutase activity
K9U02_RS00705	COG1515	deoxyribonuclease V activity
K9U02_RS00720	COG1741	Belongs to the pirin family
K9U02_RS00735	COG1741	Belongs to the pirin family
K9U02_RS00740	COG1966	Carbon starvation protein
K9U02_RS00745	COG2879	small protein
K9U02_RS00750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9U02_RS00790	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K9U02_RS00795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9U02_RS00800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K9U02_RS00805	COG2080	2 iron, 2 sulfur cluster binding
K9U02_RS00810	COG0604	alcohol dehydrogenase
K9U02_RS00810	COG3321	synthase
K9U02_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS00815	COG2203	Gaf domain
K9U02_RS00815	COG3706	GGDEF domain
K9U02_RS00815	COG4251	negative regulation of phosphorylation
K9U02_RS00815	COG5001	Diguanylate cyclase
K9U02_RS00820	COG0629	single-stranded DNA binding
K9U02_RS00825	COG0142	geranyltranstransferase activity
K9U02_RS00850	COG0527	aspartate kinase activity
K9U02_RS00855	COG0384	phenazine biosynthesis protein PhzF
K9U02_RS00860	COG0384	phenazine biosynthesis protein PhzF
K9U02_RS00870	COG1764	response to oxidative stress
K9U02_RS00875	COG0540	Belongs to the ATCase OTCase family
K9U02_RS00880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9U02_RS00885	COG1678	Uncharacterized ACR, COG1678
K9U02_RS00890	COG0519	Catalyzes the synthesis of GMP from XMP
K9U02_RS00910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K9U02_RS00925	COG4942	peptidase
K9U02_RS00945	COG0693	protein deglycase activity
K9U02_RS00955	COG1959	2 iron, 2 sulfur cluster binding
K9U02_RS00960	COG0719	Fe-S assembly protein
K9U02_RS00965	COG0396	ATPase activity
K9U02_RS00970	COG0719	Fe-S assembly protein
K9U02_RS00975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9U02_RS00985	COG2146	nitrite reductase [NAD(P)H] activity
K9U02_RS00990	COG4774	siderophore transport
K9U02_RS00995	COG3128	pkhd-type hydroxylase
K9U02_RS01020	COG1477	protein flavinylation
K9U02_RS01025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9U02_RS01040	COG1555	photosystem II stabilization
K9U02_RS01045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9U02_RS01055	COG3178	'Phosphotransferase
K9U02_RS01060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9U02_RS01070	COG0628	permease
K9U02_RS01090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9U02_RS01115	COG0271	Belongs to the BolA IbaG family
K9U02_RS01125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K9U02_RS01135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K9U02_RS01140	COG1137	ATPase activity
K9U02_RS01155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9U02_RS01175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9U02_RS01180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9U02_RS01185	COG2239	Acts as a magnesium transporter
K9U02_RS01195	COG1294	oxidase, subunit
K9U02_RS01200	COG1271	oxidase subunit
K9U02_RS01215	COG1113	amino acid transport
K9U02_RS01230	COG2197	response regulator
K9U02_RS01235	COG0531	amino acid
K9U02_RS01275	COG2814	Major facilitator Superfamily
K9U02_RS01280	COG0754	glutathionylspermidine amidase activity
K9U02_RS01305	COG1842	Phage shock protein A
K9U02_RS01325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K9U02_RS01330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K9U02_RS01340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K9U02_RS01345	COG0477	Major facilitator Superfamily
K9U02_RS01355	COG2205	protein histidine kinase activity
K9U02_RS01355	COG2198	Histidine kinase
K9U02_RS01355	COG0784	Response regulator, receiver
K9U02_RS01360	COG2353	YceI-like domain
K9U02_RS01365	COG3038	cytochrome b561
K9U02_RS01380	COG1760	l-serine dehydratase
K9U02_RS01390	COG0527	aspartate kinase activity
K9U02_RS01390	COG0460	homoserine dehydrogenase
K9U02_RS01395	COG0626	cystathionine gamma-synthase activity
K9U02_RS01400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9U02_RS01405	COG0739	heme binding
K9U02_RS01410	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K9U02_RS01415	COG1272	protein, Hemolysin III
K9U02_RS01435	COG0516	GMP reductase activity
K9U02_RS01435	COG0517	IMP dehydrogenase activity
K9U02_RS01440	COG0463	Glycosyl transferase, family 2
K9U02_RS01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9U02_RS01450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K9U02_RS01460	COG4771	TonB-dependent receptor
K9U02_RS01465	COG1309	transcriptional regulator
K9U02_RS01475	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS01505	COG0509	glycine decarboxylation via glycine cleavage system
K9U02_RS01510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K9U02_RS01520	COG0330	HflC and HflK could
K9U02_RS01525	COG1742	UPF0060 membrane protein
K9U02_RS01530	COG3956	TIGRFAM MazG family protein
K9U02_RS01540	COG0494	nUDIX hydrolase
K9U02_RS01550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9U02_RS01555	COG0837	glucose binding
K9U02_RS01570	COG3858	chitin binding
K9U02_RS01570	COG1388	LysM domain
K9U02_RS01575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9U02_RS01585	COG1472	Belongs to the glycosyl hydrolase 3 family
K9U02_RS01600	COG0531	amino acid
K9U02_RS01610	COG1486	melibiose metabolic process
K9U02_RS01620	COG3537	Alpha-1,2-mannosidase
K9U02_RS01660	COG3645	SOS response
K9U02_RS01680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K9U02_RS01710	COG3142	Participates in the control of copper homeostasis
K9U02_RS01715	COG1446	asparaginase
K9U02_RS01720	COG2304	oxidoreductase activity
K9U02_RS01725	COG1595	DNA-templated transcription, initiation
K9U02_RS01750	COG0643	Histidine kinase
K9U02_RS01750	COG0784	Response regulator, receiver
K9U02_RS01750	COG2198	Histidine kinase
K9U02_RS01755	COG0840	transmembrane signaling receptor activity
K9U02_RS01760	COG0835	chemotaxis
K9U02_RS01775	COG0189	ligase activity
K9U02_RS01785	COG1397	ADP-ribosylglycohydrolase
K9U02_RS01795	COG1199	ATP-dependent helicase activity
K9U02_RS01805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9U02_RS01810	COG1215	transferase activity, transferring glycosyl groups
K9U02_RS01820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9U02_RS01830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K9U02_RS01835	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
K9U02_RS01860	COG0837	glucose binding
K9U02_RS01875	COG1643	Atp-dependent helicase
K9U02_RS01880	COG0783	Belongs to the Dps family
K9U02_RS01885	COG0514	ATP-dependent DNA helicase (RecQ)
K9U02_RS01905	COG1187	pseudouridine synthase activity
K9U02_RS01915	COG0840	transmembrane signaling receptor activity
K9U02_RS01935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K9U02_RS01955	COG0667	Aldo Keto reductase
K9U02_RS01960	COG0602	queuosine metabolic process
K9U02_RS01970	COG2885	chlorophyll binding
K9U02_RS01975	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS01985	COG0848	biopolymer transport protein
K9U02_RS01995	COG0824	Thioesterase
K9U02_RS02000	COG2255	four-way junction helicase activity
K9U02_RS02055	COG0477	Major facilitator Superfamily
K9U02_RS02090	COG0488	(ABC) transporter
K9U02_RS02120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9U02_RS02120	COG4651	solute:proton antiporter activity
K9U02_RS02145	COG4772	TonB-dependent receptor
K9U02_RS02155	COG4264	IucA IucC family
K9U02_RS02160	COG2814	Major facilitator Superfamily
K9U02_RS02165	COG4264	IucA IucC family
K9U02_RS02170	COG0019	diaminopimelate decarboxylase activity
K9U02_RS02195	COG4206	TonB-dependent receptor
K9U02_RS02205	COG0542	response to heat
K9U02_RS02210	COG1116	anion transmembrane transporter activity
K9U02_RS02215	COG1116	anion transmembrane transporter activity
K9U02_RS02220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9U02_RS02225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9U02_RS02230	COG0667	Aldo Keto reductase
K9U02_RS02235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9U02_RS02240	COG4771	TonB-dependent receptor
K9U02_RS02285	COG1877	trehalose-phosphatase activity
K9U02_RS02290	COG3387	PFAM Glycoside hydrolase 15-related
K9U02_RS02305	COG0840	transmembrane signaling receptor activity
K9U02_RS02315	COG1496	oxidoreductase activity
K9U02_RS02320	COG0564	pseudouridine synthase activity
K9U02_RS02325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9U02_RS02335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K9U02_RS02335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9U02_RS02345	COG0045	succinate-CoA ligase (ADP-forming) activity
K9U02_RS02375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K9U02_RS02395	COG0745	RESPONSE REGULATOR receiver
K9U02_RS02405	COG0189	ligase activity
K9U02_RS02480	COG0270	DNA (cytosine-5-)-methyltransferase activity
K9U02_RS02720	COG5001	Diguanylate cyclase
K9U02_RS02890	COG0583	DNA-binding transcription factor activity
K9U02_RS02895	COG1396	sequence-specific DNA binding
K9U02_RS02915	COG0582	viral genome integration into host DNA
K9U02_RS02945	COG3273	potassium ion transport
K9U02_RS02945	COG0471	metal ion transport
K9U02_RS02965	COG1970	mechanosensitive ion channel activity
K9U02_RS02975	COG1609	Transcriptional regulator
K9U02_RS02985	COG3250	beta-galactosidase activity
K9U02_RS02990	COG4948	Mandelate Racemase Muconate Lactonizing
K9U02_RS03000	COG2272	Belongs to the type-B carboxylesterase lipase family
K9U02_RS03005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9U02_RS03030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9U02_RS03035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS03050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9U02_RS03055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9U02_RS03060	COG0175	sulfate reduction
K9U02_RS03080	COG2205	protein histidine kinase activity
K9U02_RS03080	COG2198	Histidine kinase
K9U02_RS03080	COG0784	Response regulator, receiver
K9U02_RS03095	COG1648	precorrin-2 dehydrogenase activity
K9U02_RS03095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9U02_RS03110	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
K9U02_RS03115	COG3588	fructose-bisphosphate aldolase
K9U02_RS03120	COG0469	pyruvate kinase activity
K9U02_RS03150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9U02_RS03165	COG3047	cAMP biosynthetic process
K9U02_RS03175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9U02_RS03175	COG3453	Protein conserved in bacteria
K9U02_RS03180	COG0725	ABC transporter, periplasmic molybdate-binding protein
K9U02_RS03185	COG4149	molybdate abc transporter
K9U02_RS03190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K9U02_RS03235	COG1376	ErfK ybiS ycfS ynhG family protein
K9U02_RS03240	COG0739	heme binding
K9U02_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS03250	COG0583	DNA-binding transcription factor activity
K9U02_RS03255	COG4773	Receptor
K9U02_RS03260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9U02_RS03265	COG1301	dicarboxylic acid transport
K9U02_RS03295	COG0714	Associated with various cellular activities
K9U02_RS03325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9U02_RS03350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9U02_RS03360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9U02_RS03375	COG1561	YicC-like family, N-terminal region
K9U02_RS03380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K9U02_RS03395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9U02_RS03410	COG0006	proline dipeptidase activity
K9U02_RS03420	COG0006	proline dipeptidase activity
K9U02_RS03445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9U02_RS03465	COG2912	Transglutaminase-like superfamily
K9U02_RS03475	COG1773	rubredoxin
K9U02_RS03480	COG0352	thiamine-phosphate diphosphorylase activity
K9U02_RS03490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K9U02_RS03505	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
K9U02_RS03510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9U02_RS03540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9U02_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS03570	COG0671	phosphoesterase, PA-phosphatase related
K9U02_RS03575	COG3781	membrane
K9U02_RS03585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9U02_RS03590	COG0563	adenylate kinase activity
K9U02_RS03605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K9U02_RS03615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K9U02_RS03635	COG3710	Transcriptional regulator
K9U02_RS03640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K9U02_RS03650	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS03650	COG1506	peptidase
K9U02_RS03650	COG4946	Tricorn protease homolog
K9U02_RS03660	COG0405	Gamma-glutamyltransferase
K9U02_RS03665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K9U02_RS03685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9U02_RS03690	COG0473	3-isopropylmalate dehydrogenase activity
K9U02_RS03705	COG0066	3-isopropylmalate dehydratase activity
K9U02_RS03710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K9U02_RS03730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9U02_RS03735	COG1538	Outer membrane efflux protein
K9U02_RS03740	COG1519	Transferase
K9U02_RS03745	COG1560	Kdo2-lipid A biosynthetic process
K9U02_RS03770	COG0280	phosphate acetyltransferase
K9U02_RS03770	COG0281	malic enzyme
K9U02_RS03785	COG4191	Histidine kinase
K9U02_RS03800	COG0583	DNA-binding transcription factor activity
K9U02_RS03810	COG0667	Aldo Keto reductase
K9U02_RS03815	COG2197	response regulator
K9U02_RS03825	COG0642	Histidine kinase
K9U02_RS03840	COG2851	Citrate transporter
K9U02_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS03850	COG1609	Transcriptional regulator
K9U02_RS03855	COG2211	Major facilitator Superfamily
K9U02_RS03945	COG4773	Receptor
K9U02_RS03950	COG0726	polysaccharide deacetylase
K9U02_RS03955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9U02_RS03970	COG3964	amidohydrolase
K9U02_RS03975	COG1228	amidohydrolase
K9U02_RS04020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9U02_RS04025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9U02_RS04050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9U02_RS04050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9U02_RS04065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9U02_RS04075	COG0488	(ABC) transporter
K9U02_RS04080	COG0242	peptide deformylase activity
K9U02_RS04145	COG2188	Transcriptional regulator
K9U02_RS04155	COG1450	Type ii and iii secretion system protein
K9U02_RS04170	COG3166	PFAM Fimbrial assembly family protein
K9U02_RS04175	COG3156	type II secretion system protein K
K9U02_RS04180	COG4795	General secretion pathway protein
K9U02_RS04185	COG2165	general secretion pathway protein
K9U02_RS04190	COG4970	Tfp pilus assembly protein FimT
K9U02_RS04195	COG2165	general secretion pathway protein
K9U02_RS04200	COG1459	type II secretion system
K9U02_RS04205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9U02_RS04210	COG1404	Belongs to the peptidase S8 family
K9U02_RS04220	COG1404	Belongs to the peptidase S8 family
K9U02_RS04225	COG5295	Hep Hag repeat protein
K9U02_RS04230	COG0047	phosphoribosylformylglycinamidine synthase activity
K9U02_RS04230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9U02_RS04235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9U02_RS04240	COG4974	Belongs to the 'phage' integrase family
K9U02_RS04250	COG0795	lipopolysaccharide-transporting ATPase activity
K9U02_RS04270	COG0525	valine-tRNA ligase activity
K9U02_RS04295	COG1183	phosphatidylcholine synthase activity
K9U02_RS04305	COG0442	prolyl-tRNA aminoacylation
K9U02_RS04320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9U02_RS04325	COG1127	ABC transporter
K9U02_RS04330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9U02_RS04330	COG3218	ABC-type transport auxiliary lipoprotein component
K9U02_RS04360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9U02_RS04365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9U02_RS04370	COG0662	Cupin 2, conserved barrel domain protein
K9U02_RS04370	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
K9U02_RS04395	COG2086	electron transfer activity
K9U02_RS04410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9U02_RS04410	COG0546	phosphoglycolate phosphatase activity
K9U02_RS04415	COG0277	FAD linked oxidase domain protein
K9U02_RS04420	COG0300	oxidoreductase activity
K9U02_RS04425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9U02_RS04465	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS04465	COG1216	Glycosyl transferase, family 2
K9U02_RS04485	COG0626	cystathionine gamma-synthase activity
K9U02_RS04515	COG0625	glutathione transferase activity
K9U02_RS04525	COG0513	Belongs to the DEAD box helicase family
K9U02_RS04540	COG4771	TonB-dependent receptor
K9U02_RS04545	COG0720	synthase
K9U02_RS04555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K9U02_RS04560	COG1956	GAF domain-containing protein
K9U02_RS04570	COG2819	hydrolase of the alpha beta superfamily
K9U02_RS04580	COG0546	phosphoglycolate phosphatase activity
K9U02_RS04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9U02_RS04600	COG0339	signal peptide processing
K9U02_RS04645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9U02_RS04650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS04655	COG1136	(ABC) transporter
K9U02_RS04680	COG4191	Histidine kinase
K9U02_RS04690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K9U02_RS04705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K9U02_RS04725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9U02_RS04730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K9U02_RS04740	COG0356	it plays a direct role in the translocation of protons across the membrane
K9U02_RS04765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9U02_RS04775	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9U02_RS04810	COG2011	ABC-type metal ion transport system permease component
K9U02_RS04815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9U02_RS04820	COG0697	spore germination
K9U02_RS04825	COG1666	GTP binding
K9U02_RS04835	COG2198	Histidine kinase
K9U02_RS04835	COG0784	Response regulator, receiver
K9U02_RS04835	COG5002	protein histidine kinase activity
K9U02_RS04855	COG1187	pseudouridine synthase activity
K9U02_RS04880	COG2205	protein histidine kinase activity
K9U02_RS04880	COG2202	Pas domain
K9U02_RS04900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9U02_RS04905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9U02_RS04955	COG0842	Transport permease protein
K9U02_RS04960	COG1131	(ABC) transporter
K9U02_RS04965	COG0025	NhaP-type Na H and K H
K9U02_RS04975	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K9U02_RS04980	COG1573	uracil-dna glycosylase
K9U02_RS04990	COG3384	dioxygenase
K9U02_RS05000	COG0583	DNA-binding transcription factor activity
K9U02_RS05010	COG0667	Aldo Keto reductase
K9U02_RS05020	COG3590	peptidase
K9U02_RS05035	COG0531	amino acid
K9U02_RS05050	COG2972	Histidine kinase
K9U02_RS05070	COG3685	Protein conserved in bacteria
K9U02_RS05075	COG3546	catalase activity
K9U02_RS05100	COG2204	response regulator
K9U02_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS05135	COG1063	alcohol dehydrogenase
K9U02_RS05160	COG0583	DNA-binding transcription factor activity
K9U02_RS05165	COG2814	Major facilitator Superfamily
K9U02_RS05205	COG1131	(ABC) transporter
K9U02_RS05225	COG0251	oxidation-reduction process
K9U02_RS05240	COG0840	transmembrane signaling receptor activity
K9U02_RS05275	COG0659	secondary active sulfate transmembrane transporter activity
K9U02_RS05280	COG0038	chloride channel
K9U02_RS05340	COG0642	Histidine kinase
K9U02_RS05350	COG4695	Portal protein
K9U02_RS05395	COG3179	chitinase
K9U02_RS05415	COG0784	Response regulator, receiver
K9U02_RS05415	COG4191	Histidine kinase
K9U02_RS05450	COG0456	acetyltransferase
K9U02_RS05515	COG3081	Nucleoid-associated protein
K9U02_RS05605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9U02_RS05610	COG1490	D-aminoacyl-tRNA deacylase activity
K9U02_RS05615	COG1560	Kdo2-lipid A biosynthetic process
K9U02_RS05625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9U02_RS05640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K9U02_RS05660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9U02_RS05660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9U02_RS05670	COG0242	peptide deformylase activity
K9U02_RS05675	COG1652	LysM domain
K9U02_RS05680	COG0758	DNA mediated transformation
K9U02_RS05700	COG1754	DNA topoisomerase type I activity
K9U02_RS05700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K9U02_RS05705	COG0009	L-threonylcarbamoyladenylate synthase
K9U02_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS05730	COG0616	signal peptide processing
K9U02_RS05735	COG0534	Mate efflux family protein
K9U02_RS05750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K9U02_RS05755	COG0625	glutathione transferase activity
K9U02_RS05770	COG1252	NADH dehydrogenase
K9U02_RS05775	COG2860	membrane
K9U02_RS05780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9U02_RS05785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K9U02_RS05790	COG2201	protein-glutamate methylesterase activity
K9U02_RS05795	COG2177	Part of the ABC transporter FtsEX involved in
K9U02_RS05800	COG2884	Cell division ATP-binding protein ftsE
K9U02_RS05810	COG3118	belongs to the thioredoxin family
K9U02_RS05815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K9U02_RS05825	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
K9U02_RS05845	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K9U02_RS05845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K9U02_RS05850	COG1473	amidohydrolase
K9U02_RS05860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9U02_RS05870	COG5383	Protein conserved in bacteria
K9U02_RS05910	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
K9U02_RS05915	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9U02_RS05925	COG4948	Mandelate Racemase Muconate Lactonizing
K9U02_RS05935	COG0531	amino acid
K9U02_RS05950	COG4682	membrane
K9U02_RS05955	COG2133	pyrroloquinoline quinone binding
K9U02_RS05965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K9U02_RS05980	COG1610	YqeY-like protein
K9U02_RS05985	COG1295	ribonuclease BN
K9U02_RS05990	COG0358	DNA primase activity
K9U02_RS06010	COG0109	protoheme IX farnesyltransferase activity
K9U02_RS06040	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K9U02_RS06055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9U02_RS06100	COG0739	heme binding
K9U02_RS06115	COG2211	Major facilitator Superfamily
K9U02_RS06120	COG0708	Exodeoxyribonuclease III
K9U02_RS06135	COG1192	Involved in chromosome partitioning
K9U02_RS06140	COG1475	DNA binding
K9U02_RS06160	COG0463	Glycosyl transferase, family 2
K9U02_RS06185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K9U02_RS06195	COG0018	arginyl-trna synthetase
K9U02_RS06210	COG4221	oxidoreductase activity
K9U02_RS06215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K9U02_RS06215	COG2755	lipolytic protein G-D-S-L family
K9U02_RS06225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9U02_RS06225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9U02_RS06230	COG1166	arginine decarboxylase activity
K9U02_RS06235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K9U02_RS06265	COG2960	long-chain fatty acid transporting porin activity
K9U02_RS06305	COG0210	DNA helicase
K9U02_RS06355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
K9U02_RS06405	COG1090	epimerase
K9U02_RS06415	COG0642	Histidine kinase
K9U02_RS06455	COG0628	permease
K9U02_RS06460	COG1011	Hydrolase
K9U02_RS06465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K9U02_RS06495	COG2197	response regulator
K9U02_RS06500	COG4585	Histidine kinase
K9U02_RS06505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS06510	COG1136	(ABC) transporter
K9U02_RS06535	COG0697	spore germination
K9U02_RS06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9U02_RS06555	COG0180	Tryptophanyl-tRNA synthetase
K9U02_RS06560	COG3237	CsbD-like
K9U02_RS06600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K9U02_RS06615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K9U02_RS06620	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K9U02_RS06620	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K9U02_RS06660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9U02_RS06685	COG1199	ATP-dependent helicase activity
K9U02_RS06745	COG0625	glutathione transferase activity
K9U02_RS06780	COG4555	ABC transporter
K9U02_RS06790	COG1476	TRANSCRIPTIONal
K9U02_RS06825	COG1131	(ABC) transporter
K9U02_RS06830	COG0842	Transport permease protein
K9U02_RS06835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K9U02_RS06845	COG1607	acyl-coa hydrolase
K9U02_RS06860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9U02_RS06865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9U02_RS06875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9U02_RS06875	COG0045	succinate-CoA ligase (ADP-forming) activity
K9U02_RS06875	COG1042	CoA-binding domain protein
K9U02_RS06880	COG2239	Acts as a magnesium transporter
K9U02_RS06890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9U02_RS06895	COG3387	PFAM Glycoside hydrolase 15-related
K9U02_RS06910	COG3100	YcgL domain-containing protein
K9U02_RS06915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9U02_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS06965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9U02_RS06980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9U02_RS07060	COG0210	DNA helicase
K9U02_RS07070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9U02_RS07075	COG0583	DNA-binding transcription factor activity
K9U02_RS07080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9U02_RS07090	COG2159	amidohydrolase
K9U02_RS07110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS07130	COG0357	Ribosomal RNA small subunit methyltransferase G
K9U02_RS07135	COG3540	Alkaline phosphatase
K9U02_RS07145	COG2091	lysine biosynthetic process via aminoadipic acid
K9U02_RS07165	COG1940	carbohydrate kinase activity
K9U02_RS07175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9U02_RS07185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9U02_RS07230	COG3507	Belongs to the glycosyl hydrolase 43 family
K9U02_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS07250	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9U02_RS07255	COG4948	Mandelate Racemase Muconate Lactonizing
K9U02_RS07265	COG3254	rhamnose metabolic process
K9U02_RS07270	COG0738	Major facilitator superfamily
K9U02_RS07275	COG1414	Transcriptional regulator
K9U02_RS07280	COG1971	Probably functions as a manganese efflux pump
K9U02_RS07285	COG0784	Response regulator, receiver
K9U02_RS07285	COG2205	protein histidine kinase activity
K9U02_RS07290	COG3459	Glycosyltransferase 36 associated
K9U02_RS07295	COG2211	Major facilitator Superfamily
K9U02_RS07300	COG3265	gluconokinase activity
K9U02_RS07305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9U02_RS07325	COG2911	Protein conserved in bacteria
K9U02_RS07330	COG0729	surface antigen
K9U02_RS07335	COG4771	TonB-dependent receptor
K9U02_RS07340	COG0457	Tetratricopeptide repeat
K9U02_RS07355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9U02_RS07360	COG0519	Catalyzes the synthesis of GMP from XMP
K9U02_RS07360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9U02_RS07370	COG0805	protein transport
K9U02_RS07375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9U02_RS07380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9U02_RS07390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K9U02_RS07405	COG2974	May be involved in recombination
K9U02_RS07410	COG0037	tRNA processing
K9U02_RS07425	COG3661	Belongs to the glycosyl hydrolase 67 family
K9U02_RS07435	COG4948	Mandelate Racemase Muconate Lactonizing
K9U02_RS07445	COG1472	Belongs to the glycosyl hydrolase 3 family
K9U02_RS07450	COG0246	Mannitol dehydrogenase
K9U02_RS07475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9U02_RS07505	COG3250	beta-galactosidase activity
K9U02_RS07510	COG1904	glucuronate isomerase
K9U02_RS07530	COG2211	Major facilitator Superfamily
K9U02_RS07580	COG0604	alcohol dehydrogenase
K9U02_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS07580	COG3321	synthase
K9U02_RS07585	COG2937	Belongs to the GPAT DAPAT family
K9U02_RS07615	COG0284	orotidine-5'-phosphate decarboxylase activity
K9U02_RS07620	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K9U02_RS07625	COG3132	Protein of unknown function, DUF480
K9U02_RS07640	COG0210	DNA helicase
K9U02_RS07645	COG1435	thymidine kinase activity
K9U02_RS07655	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
K9U02_RS07665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K9U02_RS07695	COG3135	benzoate transporter
K9U02_RS07720	COG0676	glucose-6-phosphate 1-epimerase activity
K9U02_RS07745	COG0730	response to heat
K9U02_RS07770	COG0302	gtp cyclohydrolase
K9U02_RS07785	COG1566	PFAM secretion protein HlyD family protein
K9U02_RS07795	COG1289	transmembrane transporter activity
K9U02_RS07800	COG0477	Major facilitator Superfamily
K9U02_RS07810	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
K9U02_RS07815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9U02_RS07880	COG0564	pseudouridine synthase activity
K9U02_RS07910	COG3549	Plasmid maintenance system killer
K9U02_RS07915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9U02_RS07920	COG1074	ATP-dependent DNA helicase activity
K9U02_RS07925	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K9U02_RS07965	COG1127	ABC transporter
K9U02_RS07970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9U02_RS07975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9U02_RS07990	COG2853	Lipoprotein
K9U02_RS08000	COG0386	Belongs to the glutathione peroxidase family
K9U02_RS08010	COG1322	Protein conserved in bacteria
K9U02_RS08020	COG0531	amino acid
K9U02_RS08025	COG3537	Alpha-1,2-mannosidase
K9U02_RS08040	COG3706	GGDEF domain
K9U02_RS08050	COG1929	Belongs to the glycerate kinase type-1 family
K9U02_RS08055	COG2271	Major facilitator Superfamily
K9U02_RS08105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K9U02_RS08110	COG0861	Integral membrane protein TerC family
K9U02_RS08120	COG0584	glycerophosphoryl diester phosphodiesterase
K9U02_RS08130	COG0671	phosphoesterase, PA-phosphatase related
K9U02_RS08135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K9U02_RS08140	COG0726	polysaccharide deacetylase
K9U02_RS08145	COG0706	membrane insertase activity
K9U02_RS08160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K9U02_RS08175	COG0187	DNA topoisomerase II activity
K9U02_RS08185	COG0501	Belongs to the peptidase M48B family
K9U02_RS08220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9U02_RS08230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9U02_RS08260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9U02_RS08265	COG0793	Belongs to the peptidase S41A family
K9U02_RS08270	COG4942	peptidase
K9U02_RS08280	COG2234	aminopeptidase activity
K9U02_RS08290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9U02_RS08295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9U02_RS08300	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9U02_RS08305	COG1064	alcohol dehydrogenase
K9U02_RS08315	COG0493	'glutamate synthase
K9U02_RS08320	COG0070	glutamate synthase
K9U02_RS08320	COG0069	glutamate synthase activity
K9U02_RS08320	COG0067	glutamate synthase
K9U02_RS08355	COG3459	Glycosyltransferase 36 associated
K9U02_RS08405	COG1205	dead DEAH box helicase
K9U02_RS08405	COG1111	helicase
K9U02_RS08410	COG1272	protein, Hemolysin III
K9U02_RS08450	COG0583	DNA-binding transcription factor activity
K9U02_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS08470	COG1733	regulation of RNA biosynthetic process
K9U02_RS08500	COG3237	CsbD-like
K9U02_RS08535	COG0657	acetylesterase activity
K9U02_RS08545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9U02_RS08590	COG1309	transcriptional regulator
K9U02_RS08615	COG4772	TonB-dependent receptor
K9U02_RS08625	COG2423	ornithine cyclodeaminase activity
K9U02_RS08635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9U02_RS08640	COG0765	amino acid transport
K9U02_RS08650	COG3284	Transcriptional regulator
K9U02_RS08655	COG1012	belongs to the aldehyde dehydrogenase family
K9U02_RS08685	COG1304	FMN binding
K9U02_RS08690	COG1755	Isoprenylcysteine carboxyl methyltransferase
K9U02_RS08695	COG4585	Histidine kinase
K9U02_RS08720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9U02_RS08800	COG1595	DNA-templated transcription, initiation
K9U02_RS08840	COG0366	Alpha amylase catalytic
K9U02_RS08845	COG0366	Alpha amylase catalytic
K9U02_RS08850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9U02_RS08895	COG0657	acetylesterase activity
K9U02_RS08895	COG2755	lipolytic protein G-D-S-L family
K9U02_RS08905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9U02_RS08920	COG3507	Belongs to the glycosyl hydrolase 43 family
K9U02_RS08925	COG1609	Transcriptional regulator
K9U02_RS08930	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
K9U02_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS08945	COG2755	lipolytic protein G-D-S-L family
K9U02_RS08955	COG3186	Phenylalanine-4-hydroxylase
K9U02_RS08960	COG1522	sequence-specific DNA binding
K9U02_RS08970	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9U02_RS08980	COG1119	ATPase activity
K9U02_RS08995	COG0517	IMP dehydrogenase activity
K9U02_RS08995	COG1125	glycine betaine transport
K9U02_RS09010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9U02_RS09015	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
K9U02_RS09045	COG0489	protein tyrosine kinase activity
K9U02_RS09050	COG2062	phosphohistidine phosphatase, SixA
K9U02_RS09055	COG2353	YceI-like domain
K9U02_RS09060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9U02_RS09085	COG1881	PFAM PEBP family protein
K9U02_RS09100	COG0174	glutamine synthetase
K9U02_RS09105	COG0347	Belongs to the P(II) protein family
K9U02_RS09110	COG0004	ammonium transporteR
K9U02_RS09115	COG3852	Histidine kinase
K9U02_RS09120	COG2204	response regulator
K9U02_RS09125	COG2032	superoxide dismutase activity
K9U02_RS09130	COG2032	superoxide dismutase activity
K9U02_RS09145	COG0183	Belongs to the thiolase family
K9U02_RS09185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9U02_RS09195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K9U02_RS09205	COG0028	Belongs to the TPP enzyme family
K9U02_RS09210	COG2205	protein histidine kinase activity
K9U02_RS09235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K9U02_RS09250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9U02_RS09255	COG3177	Filamentation induced by cAMP protein fic
K9U02_RS09270	COG0596	Alpha beta hydrolase
K9U02_RS09275	COG0727	PFAM Uncharacterised protein family (UPF0153)
K9U02_RS09280	COG0318	PFAM AMP-dependent synthetase and ligase
K9U02_RS09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9U02_RS09300	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9U02_RS09320	COG0564	pseudouridine synthase activity
K9U02_RS09340	COG1446	asparaginase
K9U02_RS09345	COG0339	signal peptide processing
K9U02_RS09350	COG0681	Belongs to the peptidase S26 family
K9U02_RS09375	COG0475	glutathione-regulated potassium exporter activity
K9U02_RS09380	COG0583	DNA-binding transcription factor activity
K9U02_RS09385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9U02_RS09390	COG2224	Isocitrate lyase
K9U02_RS09420	COG4770	biotin carboxylase activity
K9U02_RS09425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9U02_RS09430	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS09485	COG0523	cobalamin synthesis protein
K9U02_RS09495	COG0697	spore germination
K9U02_RS09505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K9U02_RS09510	COG1846	Transcriptional regulator
K9U02_RS09515	COG1764	response to oxidative stress
K9U02_RS09540	COG0656	L-ascorbic acid biosynthetic process
K9U02_RS09545	COG2130	NADP-dependent
K9U02_RS09560	COG1187	pseudouridine synthase activity
K9U02_RS09570	COG1643	Atp-dependent helicase
K9U02_RS09575	COG0840	transmembrane signaling receptor activity
K9U02_RS09580	COG4807	Protein conserved in bacteria
K9U02_RS09585	COG2351	hydroxyisourate hydrolase activity
K9U02_RS09590	COG2072	flavoprotein involved in K transport
K9U02_RS09610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K9U02_RS09660	COG1957	nucleoside hydrolase
K9U02_RS09685	COG0084	hydrolase, TatD family'
K9U02_RS09700	COG0583	DNA-binding transcription factor activity
K9U02_RS09705	COG2814	Major facilitator Superfamily
K9U02_RS09710	COG1404	Belongs to the peptidase S8 family
K9U02_RS09730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K9U02_RS09735	COG1902	pentaerythritol trinitrate reductase activity
K9U02_RS09755	COG2223	nitrite transmembrane transporter activity
K9U02_RS09760	COG0745	RESPONSE REGULATOR receiver
K9U02_RS09775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS09795	COG0577	efflux transmembrane transporter activity
K9U02_RS09800	COG1136	(ABC) transporter
K9U02_RS09800	COG0577	efflux transmembrane transporter activity
K9U02_RS09850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K9U02_RS09855	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9U02_RS09860	COG0583	DNA-binding transcription factor activity
K9U02_RS09885	COG0702	epimerase
K9U02_RS09890	COG1733	regulation of RNA biosynthetic process
K9U02_RS09900	COG0840	transmembrane signaling receptor activity
K9U02_RS09945	COG0129	dihydroxy-acid dehydratase activity
K9U02_RS09965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K9U02_RS10020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K9U02_RS10050	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9U02_RS10055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9U02_RS10065	COG3485	protocatechuate 3,4-dioxygenase
K9U02_RS10070	COG3485	protocatechuate 3,4-dioxygenase
K9U02_RS10080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9U02_RS10085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9U02_RS10095	COG1414	Transcriptional regulator
K9U02_RS10115	COG0445	tRNA wobble uridine modification
K9U02_RS10125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9U02_RS10165	COG0156	8-amino-7-oxononanoate synthase activity
K9U02_RS10170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K9U02_RS10175	COG1040	competence protein
K9U02_RS10250	COG4771	TonB-dependent receptor
K9U02_RS10275	COG1169	isochorismate synthase
K9U02_RS10305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9U02_RS10305	COG2226	methyltransferase
K9U02_RS10305	COG3433	isochorismatase activity
K9U02_RS10320	COG4771	TonB-dependent receptor
K9U02_RS10325	COG1132	(ABC) transporter
K9U02_RS10325	COG2375	cellular response to nickel ion
K9U02_RS10330	COG1132	(ABC) transporter
K9U02_RS10360	COG1511	domain protein
K9U02_RS10360	COG3264	Mechanosensitive ion channel
K9U02_RS10365	COG1368	sulfuric ester hydrolase activity
K9U02_RS10370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9U02_RS10375	COG2354	Protein conserved in bacteria
K9U02_RS10385	COG0297	glycogen (starch) synthase activity
K9U02_RS10390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9U02_RS10395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9U02_RS10420	COG0702	epimerase
K9U02_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS10465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9U02_RS10470	COG4221	oxidoreductase activity
K9U02_RS10485	COG0513	Belongs to the DEAD box helicase family
K9U02_RS10495	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9U02_RS10510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9U02_RS10525	COG3104	oligopeptide transport
K9U02_RS10545	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K9U02_RS10560	COG1320	monovalent cation:proton antiporter activity
K9U02_RS10565	COG2212	antiporter activity
K9U02_RS10575	COG0651	ATP synthesis coupled electron transport
K9U02_RS10580	COG1006	Multisubunit Na H antiporter MnhC subunit
K9U02_RS10585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9U02_RS10585	COG2111	Na H antiporter
K9U02_RS10630	COG0484	heat shock protein binding
K9U02_RS10650	COG1597	lipid kinase activity
K9U02_RS10670	COG0583	DNA-binding transcription factor activity
K9U02_RS10675	COG0583	DNA-binding transcription factor activity
K9U02_RS10680	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
K9U02_RS10690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9U02_RS10770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K9U02_RS10850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9U02_RS10855	COG0134	indole-3-glycerol-phosphate synthase activity
K9U02_RS10865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9U02_RS10880	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
K9U02_RS10890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9U02_RS10905	COG1051	belongs to the nudix hydrolase family
K9U02_RS10945	COG0316	Belongs to the HesB IscA family
K9U02_RS10960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
K9U02_RS10985	COG2814	Major facilitator Superfamily
K9U02_RS10990	COG1289	transmembrane transporter activity
K9U02_RS10995	COG0151	Belongs to the GarS family
K9U02_RS11000	COG0138	bifunctional purine biosynthesis protein purh
K9U02_RS11020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K9U02_RS11040	COG2264	protein methyltransferase activity
K9U02_RS11055	COG0439	Biotin carboxylase
K9U02_RS11065	COG0511	ligase activity, forming carbon-carbon bonds
K9U02_RS11070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K9U02_RS11085	COG1324	tolerance protein
K9U02_RS11090	COG2356	endonuclease I
K9U02_RS11120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9U02_RS11150	COG3712	iron ion homeostasis
K9U02_RS11175	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K9U02_RS11205	COG2353	YceI-like domain
K9U02_RS11225	COG3052	prosthetic group binding
K9U02_RS11260	COG1802	Transcriptional regulator
K9U02_RS11265	COG0546	phosphoglycolate phosphatase activity
K9U02_RS11350	COG1595	DNA-templated transcription, initiation
K9U02_RS11365	COG4206	TonB-dependent receptor
K9U02_RS11370	COG1506	peptidase
K9U02_RS11370	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS11425	COG0435	Glutathione S-transferase
K9U02_RS11460	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS11460	COG1506	peptidase
K9U02_RS11510	COG0697	spore germination
K9U02_RS11530	COG1113	amino acid transport
K9U02_RS11590	COG0840	transmembrane signaling receptor activity
K9U02_RS11595	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9U02_RS11595	COG5297	Belongs to the glycosyl hydrolase family 6
K9U02_RS11600	COG0659	secondary active sulfate transmembrane transporter activity
K9U02_RS11615	COG2943	transferase activity, transferring hexosyl groups
K9U02_RS11625	COG3275	phosphorelay sensor kinase activity
K9U02_RS11635	COG0181	hydroxymethylbilane synthase activity
K9U02_RS11660	COG1505	serine-type exopeptidase activity
K9U02_RS11665	COG0436	Aminotransferase
K9U02_RS11675	COG2832	Protein of unknown function (DUF454)
K9U02_RS11685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K9U02_RS11700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K9U02_RS11730	COG2226	methyltransferase
K9U02_RS11735	COG5001	Diguanylate cyclase
K9U02_RS11735	COG3300	MHYT domain
K9U02_RS11740	COG0308	aminopeptidase N
K9U02_RS11775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9U02_RS11785	COG3284	Transcriptional regulator
K9U02_RS11790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9U02_RS11795	COG1077	Cell shape determining protein MreB Mrl
K9U02_RS11805	COG1792	Involved in formation and maintenance of cell shape
K9U02_RS11820	COG0772	Belongs to the SEDS family
K9U02_RS11830	COG2951	lytic endotransglycosylase activity
K9U02_RS11835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K9U02_RS11840	COG1686	Belongs to the peptidase S11 family
K9U02_RS11850	COG2921	Belongs to the UPF0250 family
K9U02_RS11855	COG0321	lipoyl(octanoyl) transferase activity
K9U02_RS11860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9U02_RS11875	COG0583	DNA-binding transcription factor activity
K9U02_RS11900	COG2813	Specifically methylates the guanine in position
K9U02_RS11920	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K9U02_RS11925	COG0673	inositol 2-dehydrogenase activity
K9U02_RS11930	COG2823	Periplasmic or secreted lipoprotein
K9U02_RS11935	COG4251	negative regulation of phosphorylation
K9U02_RS11940	COG0784	Response regulator, receiver
K9U02_RS11945	COG4191	Histidine kinase
K9U02_RS11950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9U02_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS12000	COG1459	type II secretion system
K9U02_RS12050	COG3250	beta-galactosidase activity
K9U02_RS12065	COG2188	Transcriptional regulator
K9U02_RS12075	COG1609	Transcriptional regulator
K9U02_RS12080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9U02_RS12085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K9U02_RS12100	COG0617	tRNA 3'-terminal CCA addition
K9U02_RS12115	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K9U02_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
K9U02_RS12125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9U02_RS12135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9U02_RS12150	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K9U02_RS12155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K9U02_RS12170	COG2205	protein histidine kinase activity
K9U02_RS12190	COG3920	Histidine kinase
K9U02_RS12205	COG3791	Glutathione-dependent formaldehyde-activating
K9U02_RS12215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9U02_RS12225	COG0697	spore germination
K9U02_RS12245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K9U02_RS12250	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K9U02_RS12255	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K9U02_RS12260	COG2205	protein histidine kinase activity
K9U02_RS12265	COG0745	RESPONSE REGULATOR receiver
K9U02_RS12270	COG1506	peptidase
K9U02_RS12270	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS12270	COG4946	Tricorn protease homolog
K9U02_RS12275	COG0277	FAD linked oxidase domain protein
K9U02_RS12280	COG1988	membrane-bound metal-dependent
K9U02_RS12285	COG0792	nuclease activity
K9U02_RS12320	COG3116	cell division
K9U02_RS12330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9U02_RS12335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9U02_RS12355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9U02_RS12360	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9U02_RS12365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K9U02_RS12390	COG0739	heme binding
K9U02_RS12395	COG0653	protein targeting
K9U02_RS12405	COG0494	nUDIX hydrolase
K9U02_RS12420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K9U02_RS12425	COG3321	synthase
K9U02_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS12425	COG0604	alcohol dehydrogenase
K9U02_RS12445	COG0366	Alpha amylase catalytic
K9U02_RS12470	COG2226	methyltransferase
K9U02_RS12485	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K9U02_RS12515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K9U02_RS12530	COG4106	trans-aconitate 2-methyltransferase activity
K9U02_RS12535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9U02_RS12545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K9U02_RS12550	COG0667	Aldo Keto reductase
K9U02_RS12560	COG4771	TonB-dependent receptor
K9U02_RS12580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9U02_RS12585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K9U02_RS12595	COG2175	clavaminate synthase activity
K9U02_RS12605	COG4181	ATPase activity
K9U02_RS12620	COG0642	Histidine kinase
K9U02_RS12630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K9U02_RS12650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K9U02_RS12655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K9U02_RS12665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K9U02_RS12670	COG2967	ApaG domain
K9U02_RS12675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9U02_RS12680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K9U02_RS12690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K9U02_RS12695	COG0123	including yeast histone deacetylase and acetoin utilization protein
K9U02_RS12700	COG2096	Adenosyltransferase
K9U02_RS12710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9U02_RS12715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9U02_RS12745	COG3384	dioxygenase
K9U02_RS12750	COG0583	DNA-binding transcription factor activity
K9U02_RS12755	COG0318	PFAM AMP-dependent synthetase and ligase
K9U02_RS12765	COG1024	Enoyl-CoA hydratase
K9U02_RS12815	COG0697	spore germination
K9U02_RS12820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9U02_RS12845	COG2197	response regulator
K9U02_RS12855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9U02_RS12865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9U02_RS12870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9U02_RS12875	COG0583	DNA-binding transcription factor activity
K9U02_RS12880	COG3634	alkyl hydroperoxide reductase activity
K9U02_RS12890	COG2890	protein-(glutamine-N5) methyltransferase activity
K9U02_RS12910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9U02_RS12910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9U02_RS12940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K9U02_RS12985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9U02_RS12990	COG1404	Belongs to the peptidase S8 family
K9U02_RS12995	COG1404	Belongs to the peptidase S8 family
K9U02_RS13000	COG1404	Belongs to the peptidase S8 family
K9U02_RS13005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K9U02_RS13025	COG1295	ribonuclease BN
K9U02_RS13030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9U02_RS13035	COG1254	Belongs to the acylphosphatase family
K9U02_RS13050	COG0521	Mo-molybdopterin cofactor biosynthetic process
K9U02_RS13060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K9U02_RS13065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K9U02_RS13075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K9U02_RS13090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9U02_RS13095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K9U02_RS13100	COG0193	aminoacyl-tRNA hydrolase activity
K9U02_RS13105	COG0012	GTP binding
K9U02_RS13125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9U02_RS13135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K9U02_RS13140	COG0250	Participates in transcription elongation, termination and antitermination
K9U02_RS13145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K9U02_RS13150	COG0081	regulation of translation
K9U02_RS13155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K9U02_RS13160	COG0222	ribosome binding
K9U02_RS13170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K9U02_RS13175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K9U02_RS13185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K9U02_RS13190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9U02_RS13195	COG0051	transcription antitermination factor activity, RNA binding
K9U02_RS13215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K9U02_RS13225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K9U02_RS13240	COG0255	Belongs to the universal ribosomal protein uL29 family
K9U02_RS13255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K9U02_RS13275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K9U02_RS13290	COG1841	ribosomal large subunit assembly
K9U02_RS13300	COG0201	protein transport
K9U02_RS13325	COG0203	ribosomal protein L17
K9U02_RS13335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K9U02_RS13345	COG0154	amidase activity
K9U02_RS13355	COG1217	gtp-binding protein TYPA
K9U02_RS13360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9U02_RS13370	COG0625	glutathione transferase activity
K9U02_RS13385	COG1902	pentaerythritol trinitrate reductase activity
K9U02_RS13385	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9U02_RS13390	COG0604	alcohol dehydrogenase
K9U02_RS13395	COG2885	chlorophyll binding
K9U02_RS13420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K9U02_RS13425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K9U02_RS13430	COG4208	sulfate ABC transporter
K9U02_RS13435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K9U02_RS13465	COG0406	alpha-ribazole phosphatase activity
K9U02_RS13475	COG0285	dihydrofolate synthase activity
K9U02_RS13495	COG2833	Protein of unknown function (DUF455)
K9U02_RS13500	COG3291	Pkd domain containing protein
K9U02_RS13510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9U02_RS13515	COG0671	phosphoesterase, PA-phosphatase related
K9U02_RS13520	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS13530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K9U02_RS13545	COG4783	chaperone-mediated protein folding
K9U02_RS13560	COG0473	3-isopropylmalate dehydrogenase activity
K9U02_RS13595	COG0784	Response regulator, receiver
K9U02_RS13595	COG4191	Histidine kinase
K9U02_RS13605	COG0544	peptidyl-prolyl cis-trans isomerase activity
K9U02_RS13615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K9U02_RS13640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9U02_RS13650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9U02_RS13670	COG0631	protein serine/threonine phosphatase activity
K9U02_RS13685	COG0859	PFAM glycosyl transferase family 9
K9U02_RS13695	COG1234	tRNA 3'-trailer cleavage
K9U02_RS13700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K9U02_RS13705	COG0315	cyclic pyranopterin monophosphate synthase activity
K9U02_RS13710	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K9U02_RS13715	COG0314	molybdopterin synthase activity
K9U02_RS13735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K9U02_RS13740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9U02_RS13745	COG0537	adenosine 5'-monophosphoramidase activity
K9U02_RS13765	COG0714	Associated with various cellular activities
K9U02_RS13785	COG0424	maF-like protein
K9U02_RS13790	COG1399	metal-binding, possibly nucleic acid-binding protein
K9U02_RS13795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K9U02_RS13800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9U02_RS13810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K9U02_RS13815	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS13830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9U02_RS13835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9U02_RS13860	COG3829	transcription factor binding
K9U02_RS13880	COG3609	addiction module antidote protein, CC2985 family
K9U02_RS13935	COG4953	penicillin-binding protein 1C
K9U02_RS13945	COG0678	peroxiredoxin activity
K9U02_RS13965	COG0330	HflC and HflK could
K9U02_RS13970	COG0330	HflC and HflK could
K9U02_RS13985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9U02_RS13990	COG0308	aminopeptidase N
K9U02_RS14010	COG1309	transcriptional regulator
K9U02_RS14055	COG1309	transcriptional regulator
K9U02_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS14085	COG3537	Alpha-1,2-mannosidase
K9U02_RS14125	COG2323	membrane
K9U02_RS14140	COG2271	Major facilitator Superfamily
K9U02_RS14165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9U02_RS14170	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K9U02_RS14175	COG2080	2 iron, 2 sulfur cluster binding
K9U02_RS14235	COG0587	DNA-directed DNA polymerase activity
K9U02_RS14245	COG1297	OPT oligopeptide transporter protein
K9U02_RS14265	COG0823	Involved in the tonB-independent uptake of proteins
K9U02_RS14265	COG1506	peptidase
K9U02_RS14280	COG1917	Cupin 2, conserved barrel domain protein
K9U02_RS14280	COG2207	Transcriptional regulator
K9U02_RS14285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS14320	COG0753	catalase activity
K9U02_RS14325	COG0656	L-ascorbic acid biosynthetic process
K9U02_RS14330	COG2272	Belongs to the type-B carboxylesterase lipase family
K9U02_RS14335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K9U02_RS14335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K9U02_RS14370	COG2194	sulfuric ester hydrolase activity
K9U02_RS14380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K9U02_RS14385	COG0745	RESPONSE REGULATOR receiver
K9U02_RS14390	COG5002	protein histidine kinase activity
K9U02_RS14405	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K9U02_RS14410	COG2894	cell division
K9U02_RS14425	COG4585	Histidine kinase
K9U02_RS14430	COG2197	response regulator
K9U02_RS14445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K9U02_RS14480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K9U02_RS14490	COG1595	DNA-templated transcription, initiation
K9U02_RS14500	COG1946	Acyl-CoA thioesterase
K9U02_RS14505	COG1024	Enoyl-CoA hydratase
K9U02_RS14515	COG0824	Thioesterase
K9U02_RS14520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9U02_RS14530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K9U02_RS14535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K9U02_RS14545	COG0728	peptidoglycan biosynthetic process
K9U02_RS14560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K9U02_RS14565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K9U02_RS14580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9U02_RS14585	COG1845	cytochrome c oxidase, subunit III
K9U02_RS14590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K9U02_RS14605	COG3152	Membrane
K9U02_RS14615	COG2207	Transcriptional regulator
K9U02_RS14620	COG0326	Molecular chaperone. Has ATPase activity
K9U02_RS14630	COG1902	pentaerythritol trinitrate reductase activity
K9U02_RS14635	COG1366	Belongs to the anti-sigma-factor antagonist family
K9U02_RS14640	COG1366	Belongs to the anti-sigma-factor antagonist family
K9U02_RS14645	COG2172	sigma factor antagonist activity
K9U02_RS14675	COG4771	TonB-dependent receptor
K9U02_RS14685	COG5507	3-demethylubiquinone-9 3-methyltransferase
K9U02_RS14690	COG2205	protein histidine kinase activity
K9U02_RS14700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K9U02_RS14705	COG3850	Histidine kinase
K9U02_RS14705	COG2205	protein histidine kinase activity
K9U02_RS14705	COG4999	Histidine kinase
K9U02_RS14705	COG3437	response regulator, receiver
K9U02_RS14710	COG4191	Histidine kinase
K9U02_RS14710	COG0784	Response regulator, receiver
K9U02_RS14760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9U02_RS14765	COG2070	2-Nitropropane dioxygenase
K9U02_RS14785	COG0336	Belongs to the RNA methyltransferase TrmD family
K9U02_RS14805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K9U02_RS14925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K9U02_RS14940	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9U02_RS14950	COG0497	DNA recombination
K9U02_RS14955	COG1420	regulation of RNA biosynthetic process
K9U02_RS14960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K9U02_RS14965	COG0443	Heat shock 70 kDa protein
K9U02_RS14975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K9U02_RS14980	COG0287	Prephenate dehydrogenase
K9U02_RS14980	COG1605	Chorismate mutase
K9U02_RS15000	COG2274	protein secretion by the type I secretion system
K9U02_RS15005	COG0583	DNA-binding transcription factor activity
K9U02_RS15010	COG1132	(ABC) transporter
K9U02_RS15020	COG1619	proteins homologs of microcin C7 resistance protein MccF
K9U02_RS15060	COG2850	peptidyl-arginine hydroxylation
K9U02_RS15075	COG1253	flavin adenine dinucleotide binding
K9U02_RS15105	COG1131	(ABC) transporter
K9U02_RS15110	COG1725	Transcriptional regulator
K9U02_RS15120	COG0386	Belongs to the glutathione peroxidase family
K9U02_RS15135	COG2900	Belongs to the SlyX family
K9U02_RS15160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9U02_RS15170	COG0646	methionine synthase
K9U02_RS15170	COG1410	methionine synthase
K9U02_RS15175	COG0646	methionine synthase
K9U02_RS15175	COG1410	methionine synthase
K9U02_RS15180	COG2226	methyltransferase
K9U02_RS15185	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS15200	COG0557	exoribonuclease II activity
K9U02_RS15210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9U02_RS15225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9U02_RS15235	COG0704	Plays a role in the regulation of phosphate uptake
K9U02_RS15240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9U02_RS15245	COG0581	inorganic phosphate transmembrane transporter activity
K9U02_RS15250	COG0573	inorganic phosphate transmembrane transporter activity
K9U02_RS15255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9U02_RS15280	COG0659	secondary active sulfate transmembrane transporter activity
K9U02_RS15285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K9U02_RS15295	COG1024	Enoyl-CoA hydratase
K9U02_RS15305	COG0494	nUDIX hydrolase
K9U02_RS15340	COG2264	protein methyltransferase activity
K9U02_RS15345	COG0488	(ABC) transporter
K9U02_RS15360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9U02_RS15370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K9U02_RS15385	COG2925	Exonuclease
K9U02_RS15390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9U02_RS15395	COG3844	kynureninase activity
K9U02_RS15405	COG0662	Cupin 2, conserved barrel domain protein
K9U02_RS15410	COG0288	reversible hydration of carbon dioxide
K9U02_RS15475	COG0017	Asparaginyl-tRNA synthetase
K9U02_RS15480	COG0316	Belongs to the HesB IscA family
K9U02_RS15505	COG3115	cell septum assembly
K9U02_RS15515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9U02_RS15520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K9U02_RS15525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K9U02_RS15540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K9U02_RS15550	COG4993	Dehydrogenase
K9U02_RS15565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K9U02_RS15575	COG2986	histidine ammonia-lyase
K9U02_RS15580	COG1228	amidohydrolase
K9U02_RS15615	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
K9U02_RS15620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K9U02_RS15625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K9U02_RS15630	COG0077	Prephenate dehydratase
K9U02_RS15630	COG1605	Chorismate mutase
K9U02_RS15635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K9U02_RS15650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K9U02_RS15655	COG0583	DNA-binding transcription factor activity
K9U02_RS15680	COG0840	transmembrane signaling receptor activity
K9U02_RS15700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9U02_RS15715	COG0840	transmembrane signaling receptor activity
K9U02_RS15740	COG0784	Response regulator, receiver
K9U02_RS15740	COG4191	Histidine kinase
K9U02_RS15745	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K9U02_RS15750	COG4191	Histidine kinase
K9U02_RS15750	COG0784	Response regulator, receiver
K9U02_RS15765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9U02_RS15785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9U02_RS15790	COG1404	Belongs to the peptidase S8 family
K9U02_RS15800	COG1595	DNA-templated transcription, initiation
K9U02_RS15850	COG2244	polysaccharide biosynthetic process
K9U02_RS15880	COG2264	protein methyltransferase activity
K9U02_RS15885	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS15890	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS15910	COG1136	(ABC) transporter
K9U02_RS15915	COG1132	(ABC) transporter
K9U02_RS15920	COG0477	Major facilitator Superfamily
K9U02_RS15925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9U02_RS15940	COG1253	flavin adenine dinucleotide binding
K9U02_RS15990	COG0148	phosphopyruvate hydratase activity
K9U02_RS16000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K9U02_RS16005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K9U02_RS16015	COG2840	Smr protein MutS2
K9U02_RS16020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K9U02_RS16025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9U02_RS16030	COG1238	metal cluster binding
K9U02_RS16045	COG1534	Rna-binding protein
K9U02_RS16050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K9U02_RS16060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9U02_RS16075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9U02_RS16080	COG1546	Belongs to the CinA family
K9U02_RS16085	COG4771	TonB-dependent receptor
K9U02_RS16090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9U02_RS16100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K9U02_RS16105	COG2137	regulation of response to DNA damage stimulus
K9U02_RS16110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9U02_RS16115	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
K9U02_RS16135	COG1741	Belongs to the pirin family
K9U02_RS16140	COG0583	DNA-binding transcription factor activity
K9U02_RS16165	COG0352	thiamine-phosphate diphosphorylase activity
K9U02_RS16165	COG0351	phosphomethylpyrimidine kinase
K9U02_RS16180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K9U02_RS16185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9U02_RS16200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9U02_RS16210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K9U02_RS16215	COG3734	2-keto-3-deoxy-galactonokinase
K9U02_RS16225	COG4948	Mandelate Racemase Muconate Lactonizing
K9U02_RS16230	COG0800	Aldolase
K9U02_RS16265	COG1501	Belongs to the glycosyl hydrolase 31 family
K9U02_RS16275	COG1070	Carbohydrate kinase
K9U02_RS16285	COG0477	Major facilitator Superfamily
K9U02_RS16300	COG0860	N-Acetylmuramoyl-L-alanine amidase
K9U02_RS16325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K9U02_RS16330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K9U02_RS16360	COG1472	Belongs to the glycosyl hydrolase 3 family
K9U02_RS16370	COG2203	Gaf domain
K9U02_RS16370	COG3706	GGDEF domain
K9U02_RS16370	COG5001	Diguanylate cyclase
K9U02_RS16370	COG4251	negative regulation of phosphorylation
K9U02_RS16375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9U02_RS16380	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
K9U02_RS16415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K9U02_RS16435	COG1012	belongs to the aldehyde dehydrogenase family
K9U02_RS16510	COG0515	serine threonine protein kinase
K9U02_RS16510	COG2815	serine threonine protein kinase
K9U02_RS16575	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K9U02_RS16575	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K9U02_RS16600	COG1215	transferase activity, transferring glycosyl groups
K9U02_RS16605	COG0726	polysaccharide deacetylase
K9U02_RS16605	COG1649	PFAM Uncharacterised BCR, COG1649
K9U02_RS16650	COG0460	homoserine dehydrogenase
K9U02_RS16650	COG0527	aspartate kinase activity
K9U02_RS16705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9U02_RS16710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9U02_RS16715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K9U02_RS16715	COG0131	Imidazoleglycerol-phosphate dehydratase
K9U02_RS16720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9U02_RS16725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K9U02_RS16735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9U02_RS16735	COG0140	phosphoribosyl-ATP diphosphatase activity
K9U02_RS16765	COG0531	amino acid
K9U02_RS16770	COG0531	amino acid
K9U02_RS16780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9U02_RS16785	COG0277	FAD linked oxidase domain protein
K9U02_RS16805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9U02_RS16845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9U02_RS16850	COG2258	MOSC domain
K9U02_RS16860	COG0505	Belongs to the CarA family
K9U02_RS16870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K9U02_RS16875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9U02_RS16885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K9U02_RS16900	COG3279	Response regulator of the LytR AlgR family
K9U02_RS16910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K9U02_RS16920	COG2198	Histidine kinase
K9U02_RS16920	COG2205	protein histidine kinase activity
K9U02_RS16920	COG0784	Response regulator, receiver
K9U02_RS16925	COG1024	Enoyl-CoA hydratase
K9U02_RS16930	COG0318	PFAM AMP-dependent synthetase and ligase
K9U02_RS16960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9U02_RS16985	COG0840	transmembrane signaling receptor activity
K9U02_RS16995	COG0835	chemotaxis
K9U02_RS17015	COG0840	transmembrane signaling receptor activity
K9U02_RS17020	COG0840	transmembrane signaling receptor activity
K9U02_RS17025	COG0840	transmembrane signaling receptor activity
K9U02_RS17030	COG0840	transmembrane signaling receptor activity
K9U02_RS17035	COG0840	transmembrane signaling receptor activity
K9U02_RS17040	COG0840	transmembrane signaling receptor activity
K9U02_RS17050	COG0840	transmembrane signaling receptor activity
K9U02_RS17055	COG0840	transmembrane signaling receptor activity
K9U02_RS17065	COG0840	transmembrane signaling receptor activity
K9U02_RS17075	COG0745	RESPONSE REGULATOR receiver
K9U02_RS17085	COG0835	chemotaxis
K9U02_RS17095	COG1360	Flagellar Motor Protein
K9U02_RS17100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K9U02_RS17160	COG0643	Histidine kinase
K9U02_RS17160	COG0784	Response regulator, receiver
K9U02_RS17160	COG2198	Histidine kinase
K9U02_RS17210	COG3300	MHYT domain
K9U02_RS17210	COG5001	Diguanylate cyclase
K9U02_RS17215	COG1684	flagellar biosynthetic protein fliR
K9U02_RS17280	COG1677	Flagellar hook-basal body complex protein FliE
K9U02_RS17310	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS17320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9U02_RS17350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9U02_RS17390	COG2201	protein-glutamate methylesterase activity
K9U02_RS17420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K9U02_RS17425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9U02_RS17430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9U02_RS17440	COG1705	Flagellar rod assembly protein muramidase FlgJ
K9U02_RS17440	COG3951	Flagellar rod assembly protein muramidase FlgJ
K9U02_RS17445	COG1706	bacterial-type flagellum-dependent cell motility
K9U02_RS17450	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K9U02_RS17460	COG4787	bacterial-type flagellum-dependent cell motility
K9U02_RS17470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K9U02_RS17475	COG1558	bacterial-type flagellum-dependent cell motility
K9U02_RS17480	COG1815	bacterial-type flagellum-dependent cell motility
K9U02_RS17485	COG0835	chemotaxis
K9U02_RS17485	COG0784	Response regulator, receiver
K9U02_RS17505	COG4191	Histidine kinase
K9U02_RS17540	COG0482	sulfurtransferase activity
K9U02_RS17555	COG0542	response to heat
K9U02_RS17565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K9U02_RS17575	COG0492	ferredoxin-NADP+ reductase activity
K9U02_RS17580	COG1674	ftsk spoiiie
K9U02_RS17600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9U02_RS17605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K9U02_RS17610	COG0183	Belongs to the thiolase family
K9U02_RS17615	COG1024	Enoyl-CoA hydratase
K9U02_RS17615	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9U02_RS17630	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K9U02_RS17640	COG1426	Protein conserved in bacteria
K9U02_RS17650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9U02_RS17655	COG1160	GTP binding
K9U02_RS17660	COG0303	'Molybdopterin
K9U02_RS17665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K9U02_RS17690	COG0708	Exodeoxyribonuclease III
K9U02_RS17700	COG0303	'Molybdopterin
K9U02_RS17705	COG0746	molybdenum cofactor guanylyltransferase activity
K9U02_RS17715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9U02_RS17715	COG1648	precorrin-2 dehydrogenase activity
K9U02_RS17740	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
K9U02_RS17755	COG0579	oxidoreductase
K9U02_RS17775	COG5001	Diguanylate cyclase
K9U02_RS17835	COG4191	Histidine kinase
K9U02_RS17835	COG0784	Response regulator, receiver
K9U02_RS17895	COG0840	transmembrane signaling receptor activity
K9U02_RS17925	COG3781	membrane
K9U02_RS17935	COG2197	response regulator
K9U02_RS17950	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS18205	COG0428	transporter
K9U02_RS18215	COG1530	ribonuclease E activity
K9U02_RS18225	COG1054	Belongs to the UPF0176 family
K9U02_RS18245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K9U02_RS18270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K9U02_RS18275	COG0322	excinuclease ABC activity
K9U02_RS18285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9U02_RS18290	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K9U02_RS18295	COG1663	tetraacyldisaccharide 4'-kinase activity
K9U02_RS18300	COG1132	(ABC) transporter
K9U02_RS18305	COG0848	biopolymer transport protein
K9U02_RS18310	COG0811	peptide transport
K9U02_RS18325	COG1136	(ABC) transporter
K9U02_RS18330	COG4591	ABC-type transport system involved in lipoprotein release permease component
K9U02_RS18340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K9U02_RS18345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9U02_RS18360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K9U02_RS18365	COG2009	succinate dehydrogenase
K9U02_RS18385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9U02_RS18390	COG0837	glucose binding
K9U02_RS18400	COG0129	dihydroxy-acid dehydratase activity
K9U02_RS18405	COG0800	Aldolase
K9U02_RS18570	COG2205	protein histidine kinase activity
K9U02_RS18570	COG5002	protein histidine kinase activity
K9U02_RS18570	COG0784	Response regulator, receiver
K9U02_RS18575	COG2183	response to ionizing radiation
K9U02_RS18585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9U02_RS18585	COG0723	plastoquinol--plastocyanin reductase activity
K9U02_RS18600	COG3243	poly(R)-hydroxyalkanoic acid synthase
K9U02_RS18610	COG1183	phosphatidylcholine synthase activity
K9U02_RS18615	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS18640	COG0668	transmembrane transport
K9U02_RS18645	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K9U02_RS18660	COG1914	H( )-stimulated, divalent metal cation uptake system
K9U02_RS18685	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS18735	COG0582	viral genome integration into host DNA
K9U02_RS18750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K9U02_RS18765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K9U02_RS18780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
K9U02_RS18795	COG0539	negative regulation of cytoplasmic translation
K9U02_RS18800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K9U02_RS18815	COG2957	Belongs to the agmatine deiminase family
K9U02_RS18820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9U02_RS18845	COG0395	ABC-type sugar transport system, permease component
K9U02_RS18850	COG1175	transmembrane transport
K9U02_RS18870	COG1609	Transcriptional regulator
K9U02_RS18880	COG2350	Protein conserved in bacteria
K9U02_RS18885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K9U02_RS18890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9U02_RS18895	COG1187	pseudouridine synthase activity
K9U02_RS18915	COG0436	Aminotransferase
K9U02_RS18920	COG4133	protoheme IX ABC transporter activity
K9U02_RS18940	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K9U02_RS18965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9U02_RS18975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K9U02_RS18980	COG4988	ABC transporter
K9U02_RS18990	COG1294	oxidase, subunit
K9U02_RS19035	COG0165	Argininosuccinate lyase
K9U02_RS19050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K9U02_RS19055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9U02_RS19060	COG0137	argininosuccinate synthase activity
K9U02_RS19065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K9U02_RS19075	COG0215	cysteine-tRNA ligase activity
K9U02_RS19080	COG2166	iron-sulfur cluster assembly
K9U02_RS19100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K9U02_RS19115	COG4303	Ethanolamine ammonia lyase large subunit
K9U02_RS19120	COG4302	ethanolamine ammonia-lyase activity
K9U02_RS19170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9U02_RS19175	COG0402	S-adenosylhomocysteine deaminase activity
K9U02_RS19185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9U02_RS19195	COG5001	Diguanylate cyclase
K9U02_RS19195	COG3300	MHYT domain
K9U02_RS19210	COG0483	inositol monophosphate 1-phosphatase activity
K9U02_RS19215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9U02_RS19230	COG0488	(ABC) transporter
K9U02_RS19235	COG0513	Belongs to the DEAD box helicase family
K9U02_RS19240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K9U02_RS19245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K9U02_RS19255	COG0625	glutathione transferase activity
K9U02_RS19270	COG4681	YaeQ
K9U02_RS19290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9U02_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS19315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9U02_RS19320	COG0860	N-Acetylmuramoyl-L-alanine amidase
K9U02_RS19330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9U02_RS19330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9U02_RS19335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9U02_RS19350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9U02_RS19375	COG2199	diguanylate cyclase activity
K9U02_RS19380	COG0835	chemotaxis
K9U02_RS19385	COG0840	transmembrane signaling receptor activity
K9U02_RS19390	COG2094	Belongs to the DNA glycosylase MPG family
K9U02_RS19395	COG1201	RNA secondary structure unwinding
K9U02_RS19405	COG2969	positive regulation of protein catabolic process
K9U02_RS19410	COG0625	glutathione transferase activity
K9U02_RS19415	COG2857	Cytochrome c1
K9U02_RS19420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K9U02_RS19425	COG0723	plastoquinol--plastocyanin reductase activity
K9U02_RS19430	COG0741	lytic transglycosylase activity
K9U02_RS19450	COG1702	phosphate starvation-inducible protein PhoH
K9U02_RS19470	COG4535	Mg2 and Co2 transporter CorC
K9U02_RS19485	COG1012	belongs to the aldehyde dehydrogenase family
K9U02_RS19495	COG1177	transmembrane transport
K9U02_RS19500	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9U02_RS19505	COG3842	ATPase activity
K9U02_RS19525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K9U02_RS19535	COG0174	glutamine synthetase
K9U02_RS19540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K9U02_RS19545	COG0174	glutamine synthetase
K9U02_RS19550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9U02_RS19560	COG2703	oxygen carrier activity
K9U02_RS19565	COG0477	Major facilitator Superfamily
K9U02_RS19575	COG0243	molybdopterin cofactor binding
K9U02_RS19585	COG2223	nitrite transmembrane transporter activity
K9U02_RS19590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9U02_RS19600	COG2733	membrane
K9U02_RS19605	COG5002	protein histidine kinase activity
K9U02_RS19605	COG0784	Response regulator, receiver
K9U02_RS19605	COG2205	protein histidine kinase activity
K9U02_RS19615	COG0477	Major facilitator Superfamily
K9U02_RS19625	COG0604	alcohol dehydrogenase
K9U02_RS19630	COG0300	oxidoreductase activity
K9U02_RS19650	COG2902	Dehydrogenase
K9U02_RS19660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS19665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9U02_RS19675	COG1609	Transcriptional regulator
K9U02_RS19680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9U02_RS19680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9U02_RS19685	COG1105	Belongs to the carbohydrate kinase PfkB family
K9U02_RS19690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9U02_RS19690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9U02_RS19700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9U02_RS19710	COG1862	Preprotein translocase
K9U02_RS19720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K9U02_RS19760	COG3291	Pkd domain containing protein
K9U02_RS19770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9U02_RS19790	COG0742	ribosomal rna small subunit methyltransferase
K9U02_RS19795	COG0326	Molecular chaperone. Has ATPase activity
K9U02_RS19875	COG0531	amino acid
K9U02_RS19890	COG0006	proline dipeptidase activity
K9U02_RS19900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9U02_RS19915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9U02_RS19920	COG3938	Belongs to the proline racemase family
K9U02_RS19930	COG0552	protein localization to endoplasmic reticulum
K9U02_RS19935	COG1194	a g-specific adenine glycosylase
K9U02_RS19945	COG4191	Histidine kinase
K9U02_RS19945	COG0784	Response regulator, receiver
K9U02_RS19955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9U02_RS19985	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS19995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K9U02_RS20015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9U02_RS20020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9U02_RS20025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9U02_RS20050	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS20060	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS20065	COG0438	transferase activity, transferring glycosyl groups
K9U02_RS20115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9U02_RS20115	COG0072	phenylalanine-tRNA ligase activity
K9U02_RS20120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K9U02_RS20135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K9U02_RS20140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K9U02_RS20155	COG2211	Major facilitator Superfamily
K9U02_RS20155	COG2190	(PTS) system
K9U02_RS20165	COG1082	Xylose isomerase domain protein TIM barrel
K9U02_RS20255	COG3702	type iv secretory pathway
K9U02_RS20275	COG2948	multi-organism process
K9U02_RS20295	COG3505	Type IV secretory pathway VirD4
K9U02_RS20310	COG0556	nucleotide-excision repair
K9U02_RS20360	COG3275	phosphorelay sensor kinase activity
K9U02_RS20365	COG1611	Belongs to the LOG family
K9U02_RS20375	COG2095	MarC family integral membrane protein
K9U02_RS20380	COG1028	Short-chain dehydrogenase reductase Sdr
K9U02_RS20385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9U02_RS20420	COG1185	polyribonucleotide nucleotidyltransferase activity
K9U02_RS20425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K9U02_RS20430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9U02_RS20435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K9U02_RS20445	COG0195	Participates in both transcription termination and antitermination
K9U02_RS20450	COG0779	Required for maturation of 30S ribosomal subunits
K9U02_RS20460	COG1007	ATP synthesis coupled electron transport
K9U02_RS20480	COG0839	Belongs to the complex I subunit 6 family
K9U02_RS20485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9U02_RS20490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K9U02_RS20500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K9U02_RS20505	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
K9U02_RS20515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9U02_RS20525	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9U02_RS20545	COG4221	oxidoreductase activity
K9U02_RS20575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9U02_RS20580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K9U02_RS20585	COG0159	tryptophan synthase activity
K9U02_RS20595	COG0133	tryptophan synthase activity
K9U02_RS20610	COG0101	tRNA pseudouridine synthase activity
K9U02_RS20625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K9U02_RS20630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9U02_RS20645	COG2890	protein-(glutamine-N5) methyltransferase activity
K9U02_RS20655	COG0688	phosphatidylethanolamine metabolic process
K9U02_RS20665	COG0433	COG0433 Predicted ATPase
K9U02_RS20670	COG0494	nUDIX hydrolase
K9U02_RS20685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9U02_RS20690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9U02_RS20730	COG3706	GGDEF domain
K9U02_RS20765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9U02_RS20780	COG0583	DNA-binding transcription factor activity
K9U02_RS20795	COG0415	Belongs to the DNA photolyase family
K9U02_RS20800	COG0305	Participates in initiation and elongation during chromosome replication
K9U02_RS20810	COG0367	asparagine synthase
K9U02_RS20825	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS20840	COG0084	hydrolase, TatD family'
K9U02_RS20845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K9U02_RS20905	COG0386	Belongs to the glutathione peroxidase family
K9U02_RS20915	COG0339	signal peptide processing
K9U02_RS20975	COG2814	Major facilitator Superfamily
K9U02_RS20980	COG1566	PFAM secretion protein HlyD family protein
K9U02_RS21020	COG4774	siderophore transport
K9U02_RS21030	COG0367	asparagine synthase
K9U02_RS21040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9U02_RS21045	COG1393	Belongs to the ArsC family
K9U02_RS21105	COG0052	Belongs to the universal ribosomal protein uS2 family
K9U02_RS21110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K9U02_RS21120	COG0528	UMP kinase activity
K9U02_RS21135	COG0575	Belongs to the CDS family
K9U02_RS21140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K9U02_RS21145	COG0750	zinc metalloprotease
K9U02_RS21160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9U02_RS21170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9U02_RS21175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9U02_RS21190	COG0825	malonyl-CoA metabolic process
K9U02_RS21200	COG1981	membrane
K9U02_RS21220	COG1695	Transcriptional regulator
K9U02_RS21240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K9U02_RS21260	COG2040	homocysteine
K9U02_RS21265	COG0833	amino acid
K9U02_RS21285	COG0346	lactoylglutathione lyase activity
K9U02_RS21305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9U02_RS21305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9U02_RS21315	COG2878	Part of a membrane complex involved in electron transport
K9U02_RS21330	COG1595	DNA-templated transcription, initiation
K9U02_RS21355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9U02_RS21370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9U02_RS21375	COG0251	oxidation-reduction process
K9U02_RS21385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K9U02_RS21385	COG0392	lysyltransferase activity
K9U02_RS21425	COG2814	Major facilitator Superfamily
K9U02_RS21430	COG1902	pentaerythritol trinitrate reductase activity
K9U02_RS21450	COG2824	Alkylphosphonate utilization operon protein PhnA
K9U02_RS21460	COG1047	Peptidyl-prolyl cis-trans
K9U02_RS21505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K9U02_RS21515	COG5487	UPF0391 membrane protein
K9U02_RS21520	COG1451	nucleotide metabolic process
K9U02_RS21540	COG0183	Belongs to the thiolase family
K9U02_RS21570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K9U02_RS21570	COG1793	dna ligase
K9U02_RS21580	COG1793	dna ligase
K9U02_RS21585	COG1201	RNA secondary structure unwinding
K9U02_RS21595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9U02_RS21600	COG1278	Cold shock
K9U02_RS21605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K9U02_RS21610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K9U02_RS21615	COG1472	Belongs to the glycosyl hydrolase 3 family
K9U02_RS21620	COG3046	protein related to deoxyribodipyrimidine photolyase
K9U02_RS21625	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
K9U02_RS21630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K9U02_RS21635	COG2954	triphosphatase activity
K9U02_RS21650	COG1381	Involved in DNA repair and RecF pathway recombination
K9U02_RS21655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K9U02_RS21660	COG0571	ribonuclease III activity
K9U02_RS21675	COG0481	GTPase activity
K9U02_RS21680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9U02_RS21695	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9U02_RS21695	COG1024	Enoyl-CoA hydratase
K9U02_RS21720	COG1960	acyl-CoA dehydrogenase activity
K9U02_RS21730	COG3800	Transcriptional regulator
K9U02_RS21730	COG1396	sequence-specific DNA binding
K9U02_RS21740	COG3867	Arabinogalactan endo-beta-1,4-galactanase
K9U02_RS21745	COG3250	beta-galactosidase activity
K9U02_RS21785	COG0322	excinuclease ABC activity
K9U02_RS21805	COG2003	Belongs to the UPF0758 family
K9U02_RS21825	COG2814	Major facilitator Superfamily
K9U02_RS21850	COG0840	transmembrane signaling receptor activity
K9U02_RS21910	COG3209	COG3209 Rhs family protein
K9U02_RS21980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9U02_RS22060	COG4644	lycopene metabolic process
K9U02_RS22065	COG2951	lytic endotransglycosylase activity
K9U02_RS22120	COG1192	Involved in chromosome partitioning
K9U02_RS22155	COG1674	ftsk spoiiie