locus-tag	class	description
HG421_RS00030	ENOG4105CKW	Inner membrane protein yedI
HG421_RS00035	ENOG4105F32	YngK protein
HG421_RS00040	ENOG4105BZU	Histidine kinase
HG421_RS00045	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HG421_RS00055	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HG421_RS00080	ENOG4105K4T	epimerase
HG421_RS00115	ENOG4105BZS	acriflavin resistance protein
HG421_RS00120	ENOG4105CHR	reductase
HG421_RS00130	ENOG4105C1J	atp-dependent rna helicase
HG421_RS00145	ENOG4105C7S	Dehydrogenase
HG421_RS00155	ENOG4105CPP	Dehydrogenase, E1 component
HG421_RS00160	ENOG4107RUY	(E1 component), alpha subunit
HG421_RS00175	ENOG4105DUX	Transporter
HG421_RS00195	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HG421_RS00200	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HG421_RS00220	ENOG4105KJM	monovalent cation h antiporter subunit g
HG421_RS00225	ENOG4105W4C	monovalent cation H antiporter subunit F
HG421_RS00235	ENOG4107R4Z	monovalent cation h antiporter subunit d
HG421_RS00240	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HG421_RS00245	ENOG4105D65	subunit l
HG421_RS00265	ENOG4105NVB	glycoside hydrolase, family 19
HG421_RS00290	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HG421_RS00300	ENOG4105DJV	ribulose-phosphate 3-epimerase
HG421_RS00305	ENOG4105KD7	acetyltransferase
HG421_RS00320	ENOG4108C33	Resolvase
HG421_RS00335	ENOG4105CRQ	synthase (Component I)
HG421_RS00380	ENOG4108E16	pectate lyase
HG421_RS00410	ENOG4105VS8	Flagellar biosynthetic protein fliq
HG421_RS00430	ENOG4108HR8	type iii secretion
HG421_RS00450	ENOG4107Y59	type iii secretion
HG421_RS00465	ENOG4108JIR	Flagellum-specific ATP synthase
HG421_RS00490	ENOG4105FTC	Lytic transglycosylase catalytic
HG421_RS00520	ENOG4105DDQ	anthranilate synthase
HG421_RS00525	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HG421_RS00530	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HG421_RS00545	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HG421_RS00550	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HG421_RS00555	ENOG4105KPY	Small multidrug resistance protein
HG421_RS00585	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HG421_RS00595	ENOG4108UQY	Iron-storage protein
HG421_RS00600	ENOG4105BZU	Histidine kinase
HG421_RS00625	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HG421_RS00630	ENOG4105E09	nadh pyrophosphatase
HG421_RS00635	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HG421_RS00660	ENOG4105F2I	Transposase
HG421_RS00695	ENOG4105EM2	membrane
HG421_RS00700	ENOG4105C12	Phosphoribosylglycinamide synthetase
HG421_RS00710	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
HG421_RS00715	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HG421_RS00720	ENOG41077RS	Phosphatase
HG421_RS00745	ENOG4108HPI	phosphatidate Cytidylyltransferase
HG421_RS00750	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HG421_RS00785	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HG421_RS00790	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HG421_RS00795	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HG421_RS00800	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HG421_RS00805	ENOG4105VF7	tolerance protein
HG421_RS00810	ENOG4108K8S	endonuclease I
HG421_RS00835	ENOG4105EUP	HipA domain protein
HG421_RS00840	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HG421_RS00865	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HG421_RS00890	ENOG4108YYC	ycei family
HG421_RS00895	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS00915	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HG421_RS00930	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
HG421_RS00950	ENOG4105DRR	Transcriptional regulator, GntR family
HG421_RS00990	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HG421_RS01045	ENOG4105F2I	Transposase
HG421_RS01150	ENOG41061H0	Monooxygenase
HG421_RS01155	ENOG410642W	LysR family Transcriptional regulator
HG421_RS01160	ENOG4105EMU	Dehydrogenase
HG421_RS01185	ENOG4105CHF	Glutathione S-transferase
HG421_RS01215	ENOG4105C5Z	peptidase
HG421_RS01220	ENOG4107QS8	(LipO)protein
HG421_RS01225	ENOG4105BZU	Histidine kinase
HG421_RS01240	ENOG4105DFI	Membrane
HG421_RS01245	ENOG4105F87	Dehydratase
HG421_RS01255	ENOG4108YQE	rare lipoprotein a
HG421_RS01265	ENOG4107QUT	magnesium and cobalt transport protein CorA
HG421_RS01325	ENOG4105BZU	Histidine kinase
HG421_RS01350	ENOG4105CW0	outer membrane usher protein
HG421_RS01355	ENOG4108AF8	Chaperone
HG421_RS01360	ENOG4108WDE	Fimbrial protein
HG421_RS01385	ENOG4105BZU	Histidine kinase
HG421_RS01410	ENOG4106R7G	Glycoside hydrolase family 5
HG421_RS01415	ENOG4105CHH	sulfate transporter
HG421_RS01420	ENOG4105BZU	Histidine kinase
HG421_RS01430	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HG421_RS01440	ENOG4108HRK	Histidine kinase
HG421_RS01445	ENOG4108NEV	two component transcriptional regulator, LytTR family
HG421_RS01450	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HG421_RS01480	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HG421_RS01495	ENOG4105WD1	Membrane
HG421_RS01505	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HG421_RS01515	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG421_RS01520	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HG421_RS01525	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HG421_RS01550	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG421_RS01555	ENOG4105BZU	Histidine kinase
HG421_RS01560	ENOG4105CD8	aminopeptidase N
HG421_RS01580	ENOG4105DZG	Dehydrogenase
HG421_RS01585	ENOG4108Q1J	Extracellular solute-binding protein, family 3
HG421_RS01610	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HG421_RS01615	ENOG4107T4Z	adenosine kinase
HG421_RS01625	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HG421_RS01640	ENOG4105CNI	cell division protein FtsW
HG421_RS01645	ENOG4107WN4	Polygalacturonase
HG421_RS01650	ENOG4105CVE	Lytic murein transglycosylase
HG421_RS01655	ENOG4105K6T	rare lipoprotein A
HG421_RS01660	ENOG4105DZ1	carboxypeptidase
HG421_RS01665	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS01685	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HG421_RS01690	ENOG4105CN1	protease
HG421_RS01700	ENOG4108KSA	LysR family transcriptional regulator
HG421_RS01745	ENOG4108J5G	6-phosphogluconate dehydrogenase
HG421_RS01750	ENOG4105D9R	oxidoreductase
HG421_RS01755	ENOG4105W4M	Transport-associated protein
HG421_RS01760	ENOG4105BZU	Histidine kinase
HG421_RS01770	ENOG4105BZU	Histidine kinase
HG421_RS01780	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HG421_RS01815	ENOG4105GVR	general secretion pathway protein D
HG421_RS01820	ENOG4107QHF	type ii secretion system protein e
HG421_RS01825	ENOG4105D7Q	type ii secretion system
HG421_RS01830	ENOG4108VAU	general secretion pathway protein G
HG421_RS01840	ENOG4105X5Z	General secretion pathway protein I
HG421_RS01850	ENOG4108RTD	type II secretion system protein K
HG421_RS01875	ENOG4105CNT	hydrolase family 2
HG421_RS01900	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS01905	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HG421_RS01910	ENOG4105CE4	GlcNAc 6-P deacetylase
HG421_RS01945	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HG421_RS01955	ENOG4108K5H	permease YjgP YjgQ family protein
HG421_RS01965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG421_RS01970	ENOG4105T95	Thiol disulfide interChange protein
HG421_RS01975	ENOG4108ETH	Formylglycinamide ribotide synthetase
HG421_RS01985	ENOG4105EUR	Domain-Containing protein
HG421_RS01990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS01995	ENOG4105EUR	Domain-Containing protein
HG421_RS02000	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS02005	ENOG4107QHF	type ii secretion system protein e
HG421_RS02010	ENOG4105D7Q	type ii secretion system
HG421_RS02020	ENOG4105WMT	general secretion pathway protein h
HG421_RS02030	ENOG41069G9	General secretion pathway protein J
HG421_RS02035	ENOG4105UV2	general secretion pathway protein K
HG421_RS02040	ENOG41090VX	general secretion pathway protein L
HG421_RS02045	ENOG410678M	general secretion pathway protein M
HG421_RS02055	ENOG4105GVR	general secretion pathway protein D
HG421_RS02070	ENOG4106S9K	Transcriptional regulator
HG421_RS02115	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HG421_RS02130	ENOG4107QZ7	Cellulose synthase catalytic subunit
HG421_RS02135	ENOG4107EEX	Cellulose synthase regulator protein
HG421_RS02140	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HG421_RS02145	ENOG4105EJG	cellulose synthase
HG421_RS02165	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HG421_RS02170	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG421_RS02180	ENOG4105DHQ	Histidine kinase
HG421_RS02200	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG421_RS02225	ENOG4105C5H	ABC transporter
HG421_RS02235	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HG421_RS02240	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HG421_RS02250	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HG421_RS02265	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HG421_RS02270	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HG421_RS02280	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HG421_RS02295	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HG421_RS02300	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HG421_RS02305	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HG421_RS02310	ENOG4105C08	Histidine kinase
HG421_RS02315	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HG421_RS02325	ENOG4105CQB	FAD linked oxidase domain protein
HG421_RS02330	ENOG4105S2T	inner membrane protein YbcI
HG421_RS02380	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HG421_RS02385	ENOG4105CJN	penicillin-binding protein
HG421_RS02390	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HG421_RS02395	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HG421_RS02400	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HG421_RS02410	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HG421_RS02415	ENOG4105DFU	Cell wall formation (By similarity)
HG421_RS02420	ENOG4105CPF	Cell wall formation (By similarity)
HG421_RS02425	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HG421_RS02430	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HG421_RS02435	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HG421_RS02440	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG421_RS02450	ENOG4105DR5	peptidase
HG421_RS02465	ENOG4105M6F	mutator MutT protein
HG421_RS02475	ENOG4105SYT	Methylenetetrahydrofolate reductase
HG421_RS02540	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HG421_RS02545	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HG421_RS02555	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HG421_RS02575	ENOG4105D6F	Phosphatase
HG421_RS02590	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG421_RS02595	ENOG4108RVA	ribokinase
HG421_RS02600	ENOG4105D9N	nucleoside
HG421_RS02605	ENOG4105CPC	Aldo Keto reductase
HG421_RS02615	ENOG4105D05	Receptor
HG421_RS02660	ENOG4108I0Y	(ABC) transporter
HG421_RS02665	ENOG4108UJV	acyl-CoA thioesterase i
HG421_RS02675	ENOG4105DHQ	Histidine kinase
HG421_RS02690	ENOG41080IJ	Diacylglycerol kinase
HG421_RS02710	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HG421_RS02725	ENOG4107SM7	Transcriptional regulator
HG421_RS02730	ENOG4107T8P	acyl-Coa dehydrogenase
HG421_RS02735	ENOG4105D7T	ABC transporter
HG421_RS02740	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HG421_RS02750	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HG421_RS02755	ENOG4108UZX	fmn reductase
HG421_RS02775	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HG421_RS02780	ENOG4105NWN	ApaG protein
HG421_RS02790	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HG421_RS02795	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HG421_RS02800	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HG421_RS02810	ENOG4108WBT	adenosyltransferase
HG421_RS02820	ENOG4105D0A	hydroxylase
HG421_RS02825	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HG421_RS02865	ENOG4105DDW	LysR family Transcriptional regulator
HG421_RS02870	ENOG4105CEY	Amp-dependent synthetase and ligase
HG421_RS02880	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HG421_RS02925	ENOG4105DXC	membrane
HG421_RS02930	ENOG4105CX6	glutaminyL-tRNA synthetase
HG421_RS02950	ENOG4105BZU	Histidine kinase
HG421_RS02955	ENOG4105WH1	Two component transcriptional regulator luxr family
HG421_RS02965	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HG421_RS02975	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HG421_RS02980	ENOG4105NXH	GreA GreB family elongation factor
HG421_RS02985	ENOG4105C5Q	Transcriptional regulator
HG421_RS03000	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HG421_RS03020	ENOG4105C2M	dna polymerase I
HG421_RS03050	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG421_RS03070	ENOG4105W8H	transhydrogenase (subunit alpha
HG421_RS03075	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG421_RS03090	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HG421_RS03095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS03100	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS03105	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS03115	ENOG4108Z66	YbaK ebsC protein
HG421_RS03130	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HG421_RS03135	ENOG4107S2Z	UPF0761 membrane protein
HG421_RS03140	ENOG4107QX9	Thiol disulfide interChange protein
HG421_RS03155	ENOG4105CSR	polyphosphate kinase 2
HG421_RS03160	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HG421_RS03175	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HG421_RS03180	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HG421_RS03185	ENOG4105QVB	outer membrane lipoprotein LolB
HG421_RS03190	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HG421_RS03200	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HG421_RS03205	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HG421_RS03210	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HG421_RS03215	ENOG4105C3G	gtp-binding protein
HG421_RS03235	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HG421_RS03245	ENOG4105PM1	preprotein translocase subunit SecE
HG421_RS03250	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HG421_RS03255	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HG421_RS03260	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HG421_RS03265	ENOG4108VZM	50s ribosomal protein L10
HG421_RS03270	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HG421_RS03275	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG421_RS03280	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG421_RS03285	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HG421_RS03295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HG421_RS03300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HG421_RS03305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HG421_RS03315	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HG421_RS03325	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HG421_RS03330	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HG421_RS03340	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HG421_RS03365	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HG421_RS03405	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HG421_RS03410	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HG421_RS03440	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HG421_RS03445	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HG421_RS03455	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HG421_RS03465	ENOG4105CI3	gtp-binding protein typa
HG421_RS03470	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HG421_RS03475	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HG421_RS03480	ENOG4108K3A	Glutathione S-transferase
HG421_RS03495	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG421_RS03500	ENOG4105CIS	alcohol dehydrogenase
HG421_RS03505	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HG421_RS03515	ENOG4108R99	pseudouridine synthase
HG421_RS03525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HG421_RS03530	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HG421_RS03535	ENOG4108I5D	sulfate abc transporter
HG421_RS03545	ENOG4108IJ6	ABC transporter
HG421_RS03565	ENOG4105HSS	phospholipase C
HG421_RS03575	ENOG4105CVJ	phosphoglycerate mutase
HG421_RS03585	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HG421_RS03600	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HG421_RS03605	ENOG4105ED9	Protein of unknown function (DUF455)
HG421_RS03610	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
HG421_RS03620	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HG421_RS03625	ENOG4105EYK	Phosphatidylglycerophosphatase B
HG421_RS03630	ENOG4105BZF	Glycosyl transferase (Group 1
HG421_RS03635	ENOG4105C9X	ppx gppa phosphatase
HG421_RS03640	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HG421_RS03645	ENOG4105BZU	Histidine kinase
HG421_RS03650	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG421_RS03655	ENOG4105ERG	peptidase m48, ste24p
HG421_RS03660	ENOG4105VW4	glutaredoxin 3
HG421_RS03670	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG421_RS03710	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HG421_RS03720	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HG421_RS03750	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HG421_RS03755	ENOG41068JE	domain protein
HG421_RS03760	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HG421_RS03770	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HG421_RS03775	ENOG4107RZZ	dna polymerase iii epsilon subunit
HG421_RS03780	ENOG4108ZF3	Phosphatase
HG421_RS03795	ENOG4105DKP	glycosyl transferase, family 9
HG421_RS03805	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HG421_RS03810	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HG421_RS03825	ENOG4105M00	molybdopterin converting factor, subunit 1
HG421_RS03830	ENOG4108ZAF	Molybdopterin
HG421_RS03870	ENOG4105W5Q	DNA repair protein (RadC
HG421_RS03900	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HG421_RS03920	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HG421_RS03925	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HG421_RS03930	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HG421_RS03935	ENOG4105K59	histidine triad (HIT) protein
HG421_RS03945	ENOG4105F8C	transglutaminase domain-containing protein
HG421_RS03955	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG421_RS03965	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
HG421_RS03975	ENOG4108UHJ	MAF-like protein
HG421_RS03980	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HG421_RS03990	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HG421_RS04000	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HG421_RS04005	ENOG4105CHR	reductase
HG421_RS04015	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG421_RS04025	ENOG4105HHA	aminodeoxychorismate lyase
HG421_RS04030	ENOG4107QRG	dna polymerase iii
HG421_RS04050	ENOG4108JU7	Transcriptional regulator
HG421_RS04055	ENOG4105CR4	methylisocitrate lyase
HG421_RS04060	ENOG4105BZN	citrate synthase
HG421_RS04065	ENOG4108I0Z	Aconitate hydratase
HG421_RS04070	ENOG4105YAJ	CopG Arc MetJ
HG421_RS04080	ENOG4105C7F	AcnD-accessory protein PrpF
HG421_RS04095	ENOG4105DN3	alpha-2-macroglobulin domain protein
HG421_RS04115	ENOG4108JQB	penicillin-binding protein 1C
HG421_RS04145	ENOG4105M3Z	response regulator
HG421_RS04150	ENOG4107QJR	hflk protein
HG421_RS04155	ENOG4105EPW	hflc protein
HG421_RS04220	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HG421_RS04225	ENOG4108XFH	Transcriptional regulator
HG421_RS04255	ENOG4105CVR	type I restriction-modification system
HG421_RS04260	ENOG41062MS	nucleotidyltransferase substrate binding protein
HG421_RS04265	ENOG41060A7	DNA polymerase beta domain protein region
HG421_RS04280	ENOG4105DZR	Type I site-specific deoxyribonuclease
HG421_RS04300	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HG421_RS04310	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HG421_RS04320	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HG421_RS04330	ENOG4105CWX	Alpha-1,2-mannosidase
HG421_RS04365	ENOG4105C7W	Xanthine dehydrogenase
HG421_RS04370	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HG421_RS04375	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HG421_RS04410	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HG421_RS04425	ENOG4105C0B	DNA polymerase III (alpha subunit)
HG421_RS04435	ENOG4105EPD	Oligopeptide transporter, Opt family
HG421_RS04445	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HG421_RS04455	ENOG4106AXJ	AraC family transcriptional regulator
HG421_RS04465	ENOG4105CV8	reductase
HG421_RS04470	ENOG4105EBR	Carboxylesterase
HG421_RS04475	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG421_RS04480	ENOG4105C2C	drug resistance transporter, Bcr CflA
HG421_RS04495	ENOG4105DIJ	Phosphoethanolamine transferase
HG421_RS04510	ENOG4105ETX	regulatoR
HG421_RS04515	ENOG4105DHQ	Histidine kinase
HG421_RS04530	ENOG4107QMS	site-determining protein
HG421_RS04535	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HG421_RS04545	ENOG4105BZU	Histidine kinase
HG421_RS04550	ENOG4105WH1	Two component transcriptional regulator luxr family
HG421_RS04600	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HG421_RS04620	ENOG4105C29	acyl-CoA thioesterase
HG421_RS04635	ENOG4108TGP	Thioesterase superfamily protein
HG421_RS04640	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HG421_RS04645	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HG421_RS04650	ENOG4105K46	50S ribosomal protein l27
HG421_RS04665	ENOG4105CJR	Integral membrane protein (MviN
HG421_RS04670	ENOG4105DTN	riboflavin biosynthesis protein ribF
HG421_RS04675	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HG421_RS04680	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HG421_RS04685	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HG421_RS04695	ENOG4105E2S	oxidase) subunit II
HG421_RS04700	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HG421_RS04705	ENOG4105CCU	oxidase (Subunit III)
HG421_RS04710	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HG421_RS04720	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HG421_RS04725	ENOG4105KAF	membrAne
HG421_RS04745	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HG421_RS04755	ENOG4107MMM	Anti-sigma-factor antagonist
HG421_RS04760	ENOG4105FUA	antagonist
HG421_RS04765	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HG421_RS04775	ENOG4105BZU	Histidine kinase
HG421_RS04785	ENOG4107ZSV	Receptor
HG421_RS04795	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HG421_RS04800	ENOG4105C08	Histidine kinase
HG421_RS04805	ENOG4107Z5C	methylesterase
HG421_RS04810	ENOG4105BZU	Histidine kinase
HG421_RS04815	ENOG4105BZU	Histidine kinase
HG421_RS04820	ENOG4105BZU	Histidine kinase
HG421_RS04840	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HG421_RS04845	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HG421_RS04850	ENOG4105CRE	cytochrome C
HG421_RS04855	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HG421_RS04860	ENOG4105EA8	2-Nitropropane dioxygenase
HG421_RS04875	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HG421_RS04890	ENOG4107QJQ	Mate efflux family protein
HG421_RS04895	ENOG4105VEJ	Heat shock protein
HG421_RS04900	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HG421_RS04910	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HG421_RS04915	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS04930	ENOG4105CNT	hydrolase family 2
HG421_RS04935	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
HG421_RS04950	ENOG4105C26	Dehydrogenase
HG421_RS04955	ENOG4105C1G	acyl-Coa dehydrogenase
HG421_RS04960	ENOG4105E39	Enoyl-CoA hydratase
HG421_RS04965	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG421_RS04970	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HG421_RS04995	ENOG4107RDJ	Sulfotransferase
HG421_RS05005	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG421_RS05010	ENOG4105EMN	RNA polymerase sigma factor
HG421_RS05020	ENOG4105C0H	protease
HG421_RS05025	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HG421_RS05030	ENOG4105C3F	Signal peptidase i
HG421_RS05040	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HG421_RS05060	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HG421_RS05070	ENOG4107ZXU	DSBA oxidoreductase
HG421_RS05075	ENOG4105BZ8	glutamate synthase
HG421_RS05080	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HG421_RS05085	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HG421_RS05090	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HG421_RS05100	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HG421_RS05105	ENOG4105VEQ	Cold shock protein
HG421_RS05110	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HG421_RS05120	ENOG4107QRT	dEAD DEAH box helicase
HG421_RS05125	ENOG4107T0X	DNA ligase
HG421_RS05135	ENOG4107T0X	DNA ligase
HG421_RS05165	ENOG4105CHU	acetyl-coa acetyltransferase
HG421_RS05185	ENOG4108VKG	metal-dependent hydrolase
HG421_RS05200	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HG421_RS05225	ENOG4105DFF	Rod shape-determining protein mreb
HG421_RS05230	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HG421_RS05240	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HG421_RS05255	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG421_RS05260	ENOG4105F27	Major Facilitator
HG421_RS05300	ENOG4105M4H	endoribonuclease L-psp
HG421_RS05305	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HG421_RS05320	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HG421_RS05345	ENOG4105K6V	RNA polymerase
HG421_RS05360	ENOG4108R3D	Electron transport complex
HG421_RS05370	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HG421_RS05390	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HG421_RS05395	ENOG4108IQI	permease
HG421_RS05400	ENOG4107QK5	Homocysteine s-methyltransferase
HG421_RS05450	ENOG4108YXA	Membrane
HG421_RS05460	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HG421_RS05470	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HG421_RS05475	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG421_RS05480	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG421_RS05490	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG421_RS05500	ENOG4105DZP	Membrane-associated zinc metalloprotease
HG421_RS05505	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HG421_RS05510	ENOG4105KNE	Phosphatidate cytidylyltransferase
HG421_RS05520	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HG421_RS05525	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HG421_RS05535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HG421_RS05540	ENOG4105CE9	30S ribosomal protein S2
HG421_RS05575	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HG421_RS05580	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HG421_RS05590	ENOG4105KUZ	arsenate reductase
HG421_RS05595	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HG421_RS05605	ENOG4105CAQ	asparagine synthetase
HG421_RS05615	ENOG4108ESX	Receptor
HG421_RS05625	ENOG4108UWD	Iron-storage protein
HG421_RS05630	ENOG4105FQ6	thiopurine methyltransferase
HG421_RS05635	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG421_RS05655	ENOG4105CW7	secretion protein, HlyD family
HG421_RS05660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HG421_RS05695	ENOG4105DUX	Transporter
HG421_RS05725	ENOG4105DGW	oligopeptidase A
HG421_RS05735	ENOG4105DP0	ferredoxin-NADP reductase
HG421_RS05745	ENOG4107GFK	fumarate
HG421_RS05755	ENOG4108V9Q	carbonic anhydrase
HG421_RS05760	ENOG4105HDD	phospholipase
HG421_RS05770	ENOG4105VEQ	Cold shock protein
HG421_RS05785	ENOG4105CUZ	uba thif-type nad fad binding protein
HG421_RS05790	ENOG4105F8V	Hydrolase, tatD family
HG421_RS05820	ENOG4108TSE	Transferase
HG421_RS05825	ENOG4105C1G	acyl-Coa dehydrogenase
HG421_RS05835	ENOG4108RXX	maleylacetoacetate isomerase
HG421_RS05840	ENOG4105CAQ	asparagine synthetase
HG421_RS05850	ENOG4105CDU	Replicative dna helicase
HG421_RS05855	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HG421_RS05860	ENOG4105CDV	Ompa motb domain protein
HG421_RS05865	ENOG4105CR8	Transcriptional regulator
HG421_RS05880	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG421_RS05900	ENOG4105BZU	Histidine kinase
HG421_RS05910	ENOG4106TD9	Diguanylate cyclase
HG421_RS05940	ENOG4108Z1B	Cyclase dehydrase
HG421_RS05950	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HG421_RS05955	ENOG41090R7	Ferric uptake
HG421_RS05960	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HG421_RS05965	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HG421_RS05970	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HG421_RS05975	ENOG4105CFG	Acts as a chaperone (By similarity)
HG421_RS05980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HG421_RS06015	ENOG4105DND	Transcriptional regulator
HG421_RS06020	ENOG4105BZ1	(ABC) transporter
HG421_RS06030	ENOG4108URH	decarboxylase
HG421_RS06040	ENOG4105C7S	Dehydrogenase
HG421_RS06045	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HG421_RS06055	ENOG4105EZE	Cupin 4 family protein
HG421_RS06065	ENOG4107QTF	adenylosuccinate lyase
HG421_RS06070	ENOG4105C37	(CBS) domain
HG421_RS06100	ENOG4105CZV	ABC transporter
HG421_RS06105	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HG421_RS06120	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HG421_RS06125	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HG421_RS06135	ENOG41069P5	Protein slyX homolog
HG421_RS06150	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS06160	ENOG4105D7K	pfkb domain protein
HG421_RS06170	ENOG4105C3R	Methionine synthase
HG421_RS06175	ENOG4105C3R	Methionine synthase
HG421_RS06180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG421_RS06185	ENOG4105C1G	acyl-Coa dehydrogenase
HG421_RS06200	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HG421_RS06210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HG421_RS06220	ENOG4105BZU	Histidine kinase
HG421_RS06225	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HG421_RS06230	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HG421_RS06235	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HG421_RS06240	ENOG4105E2Z	phosphate ABC transporter (Permease
HG421_RS06245	ENOG4105C8U	phosphate abc transporter
HG421_RS06250	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HG421_RS06270	ENOG4107B2H	carbonic anhydrase
HG421_RS06290	ENOG4105CSM	endonuclease III
HG421_RS06300	ENOG4105E39	Enoyl-CoA hydratase
HG421_RS06305	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HG421_RS06310	ENOG4105P8F	nudix hydrolase
HG421_RS06315	ENOG4105KHC	sulfurtransferase
HG421_RS06345	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG421_RS06360	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HG421_RS06365	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HG421_RS06375	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HG421_RS06390	ENOG4105CJB	Exodeoxyribonuclease I
HG421_RS06395	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HG421_RS06400	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HG421_RS06410	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
HG421_RS06415	ENOG41077A9	carbonic anhydrase
HG421_RS06445	ENOG4105C5S	asparaginyl-tRNA synthetase
HG421_RS06450	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HG421_RS06455	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HG421_RS06460	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HG421_RS06475	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HG421_RS06480	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG421_RS06485	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HG421_RS06490	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HG421_RS06500	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HG421_RS06505	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG421_RS06510	ENOG4105DZG	Dehydrogenase
HG421_RS06525	ENOG4105CGP	Urocanate hydratase
HG421_RS06535	ENOG4105C84	Histidine ammonia-lyase
HG421_RS06580	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HG421_RS06585	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HG421_RS06590	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HG421_RS06600	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HG421_RS06615	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HG421_RS06620	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HG421_RS06625	ENOG4105CC0	LysR family Transcriptional regulator
HG421_RS06640	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS06650	ENOG4105CQZ	Histidine kinase
HG421_RS06660	ENOG4105KWW	Biogenesis protein
HG421_RS06665	ENOG4107QX9	Thiol disulfide interChange protein
HG421_RS06670	ENOG4105DA4	cytochrome c-type biogenesis protein
HG421_RS06675	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HG421_RS06685	ENOG41060IM	Heme exporter protein
HG421_RS06700	ENOG4105EMN	RNA polymerase sigma factor
HG421_RS06735	ENOG4105EGZ	biosynthesis protein
HG421_RS06765	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG421_RS06770	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG421_RS06775	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG421_RS06790	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HG421_RS06800	ENOG4105DEN	Luciferase family
HG421_RS06830	ENOG4107S90	membrAne
HG421_RS06835	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG421_RS06845	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HG421_RS06860	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HG421_RS06865	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HG421_RS06870	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HG421_RS06875	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HG421_RS06880	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HG421_RS06885	ENOG4108DG9	Smr protein MutS2
HG421_RS06895	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HG421_RS06900	ENOG4108UM1	dedA family
HG421_RS06905	ENOG4108K5P	(LipO)protein
HG421_RS06910	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
HG421_RS06915	ENOG4105HBR	Rna-binding protein
HG421_RS06920	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HG421_RS06925	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG421_RS06930	ENOG4105EEI	dihydropteroate synthase
HG421_RS06935	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HG421_RS06945	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HG421_RS06950	ENOG4107TH8	cina domain protein
HG421_RS06970	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HG421_RS06975	ENOG4105Y3E	Modulates RecA activity (By similarity)
HG421_RS06980	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HG421_RS06995	ENOG4107SDU	Methyl-accepting chemotaxis
HG421_RS07005	ENOG4105CWB	LysR family transcriptional Regulator
HG421_RS07030	ENOG4105DWF	phosphomethylpyrimidine kinase
HG421_RS07045	ENOG4108IAB	Phoh family
HG421_RS07050	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG421_RS07065	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HG421_RS07075	ENOG4108Z4U	Ferredoxin
HG421_RS07095	ENOG4108RTU	Aldolase
HG421_RS07145	ENOG4105CMG	Carbohydrate kinase
HG421_RS07185	ENOG4105DJ0	Poly(A) Polymerase
HG421_RS07190	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG421_RS07195	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HG421_RS07200	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HG421_RS07205	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HG421_RS07270	ENOG4105KU2	hydrolase family 5
HG421_RS07275	ENOG4108UYB	regulatoR
HG421_RS07285	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HG421_RS07290	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HG421_RS07305	ENOG4108SXK	Transporter Drug Metabolite Exporter family
HG421_RS07310	ENOG4105D4A	Cell wall formation (By similarity)
HG421_RS07330	ENOG4105C26	Dehydrogenase
HG421_RS07345	ENOG4108DMH	HTH_ARAC
HG421_RS07380	ENOG4105KAV	tspo and mbr like protein
HG421_RS07410	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HG421_RS07415	ENOG4105CUT	histidyl-tRNA synthetase
HG421_RS07425	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HG421_RS07430	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HG421_RS07435	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG421_RS07440	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HG421_RS07445	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HG421_RS07455	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HG421_RS07460	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HG421_RS07475	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HG421_RS07485	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HG421_RS07490	ENOG4105CUB	amino acid
HG421_RS07495	ENOG4105CUB	amino acid
HG421_RS07510	ENOG4108JQ1	Dehydrogenase
HG421_RS07515	ENOG4105CQB	FAD linked oxidase domain protein
HG421_RS07530	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HG421_RS07540	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HG421_RS07555	ENOG4105CE1	Ferrous iron transport protein b
HG421_RS07570	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HG421_RS07575	ENOG4108RPX	mosc domain containing protein
HG421_RS07580	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HG421_RS07585	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HG421_RS07600	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HG421_RS07605	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HG421_RS07615	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HG421_RS07630	ENOG4105CRK	lysyL-tRNA synthetase
HG421_RS07635	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HG421_RS07640	ENOG4105BZU	Histidine kinase
HG421_RS07645	ENOG4105BZU	Histidine kinase
HG421_RS07650	ENOG4105E39	Enoyl-CoA hydratase
HG421_RS07655	ENOG4105CEY	Amp-dependent synthetase and ligase
HG421_RS07670	ENOG4107QM5	aconitate hydratase
HG421_RS07685	ENOG4107QIJ	Aconitate hydratase 2
HG421_RS07690	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HG421_RS07695	ENOG4105BZU	Histidine kinase
HG421_RS07710	ENOG4105BZU	Histidine kinase
HG421_RS07715	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07725	ENOG4108V3W	Chemotaxis protein, CheW
HG421_RS07735	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07740	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07745	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07750	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07755	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07760	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07765	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07780	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS07790	ENOG4105CBS	Chea signal transduction histidine kinase
HG421_RS07795	ENOG4108VYJ	response regulator receiver protein
HG421_RS07805	ENOG4108V3W	Chemotaxis protein, CheW
HG421_RS07810	ENOG4107QJE	Chromosome Partitioning Protein
HG421_RS07815	ENOG4105ER2	Ompa motb domain protein
HG421_RS07820	ENOG4105E14	MotA TolQ exbB proton channel
HG421_RS07965	ENOG4108VYJ	response regulator receiver protein
HG421_RS07970	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG421_RS07980	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HG421_RS08005	ENOG4105D7B	Flagellar biosynthesis protein flha
HG421_RS08010	ENOG4105D00	flagellar biosynthetic protein flhB
HG421_RS08015	ENOG4105BZU	Histidine kinase
HG421_RS08020	ENOG4105BZU	Histidine kinase
HG421_RS08025	ENOG4105BZU	Histidine kinase
HG421_RS08030	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HG421_RS08035	ENOG4105VS8	Flagellar biosynthetic protein fliq
HG421_RS08040	ENOG4105CN7	Flagellar biosynthetic protein FliP
HG421_RS08045	ENOG4105VTB	flagellar biosynthesis protein fliO
HG421_RS08050	ENOG4105DD5	Flagellar motor switch protein
HG421_RS08055	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HG421_RS08075	ENOG4108JIR	Flagellum-specific ATP synthase
HG421_RS08085	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HG421_RS08090	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HG421_RS08095	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HG421_RS08100	ENOG4107RGC	Glycosyl transferase, family 2
HG421_RS08140	ENOG4105CHR	reductase
HG421_RS08145	ENOG4108P1X	synthase
HG421_RS08165	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HG421_RS08170	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG421_RS08190	ENOG4105MQ3	flagellar protein FliS
HG421_RS08195	ENOG4107W9T	flagellar hook-associated
HG421_RS08215	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HG421_RS08220	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG421_RS08225	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG421_RS08230	ENOG4105CGA	flagellar basal-body rod protein FlgG
HG421_RS08235	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HG421_RS08240	ENOG4105BZE	flagellar hook protein, FlgE
HG421_RS08245	ENOG410822I	Flagellar hook capping protein
HG421_RS08250	ENOG4108ZC9	flagellar basal-body rod protein flgc
HG421_RS08280	ENOG4105BZU	Histidine kinase
HG421_RS08285	ENOG4105BZU	Histidine kinase
HG421_RS08295	ENOG4105BZU	Histidine kinase
HG421_RS08310	ENOG41075W9	High frequency lysogenization protein HflD homolog
HG421_RS08315	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HG421_RS08325	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HG421_RS08330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG421_RS08340	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HG421_RS08350	ENOG4105C3M	thioredoxin reductase
HG421_RS08355	ENOG4105CNU	cell division protein FtsK
HG421_RS08375	ENOG4105D1H	recombination factor protein RarA
HG421_RS08380	ENOG41082MI	Protein CrcB homolog
HG421_RS08385	ENOG4105CHU	acetyl-coa acetyltransferase
HG421_RS08405	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HG421_RS08425	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HG421_RS08430	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HG421_RS08435	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HG421_RS08440	ENOG4105D06	uba thif-type nad fad binding protein
HG421_RS08470	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HG421_RS08475	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HG421_RS08485	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HG421_RS08495	ENOG41089TF	bicarbonate transport system substrate-binding protein
HG421_RS08505	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HG421_RS08520	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HG421_RS08575	ENOG4105W39	Membrane
HG421_RS08585	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HG421_RS08610	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HG421_RS08620	ENOG4105DJ4	phosphatidylserine decarboxylase
HG421_RS08635	ENOG4105E18	UPF0276 protein
HG421_RS08650	ENOG4105EXG	Transcriptional regulator
HG421_RS08670	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HG421_RS08675	ENOG41090A4	Pterin carbinolamine dehydratase
HG421_RS08685	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
HG421_RS08690	ENOG4108NST	exported protein
HG421_RS08695	ENOG4105EI2	Pseudouridine synthase
HG421_RS08700	ENOG4105C03	ribonuclease
HG421_RS08725	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HG421_RS08735	ENOG4107QQG	Dehydrogenase
HG421_RS08760	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HG421_RS08780	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HG421_RS08785	ENOG4105CNM	Receptor
HG421_RS08790	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HG421_RS08795	ENOG4105BZ1	(ABC) transporter
HG421_RS08810	ENOG4108EC8	DNA internalization-related competence protein ComEC
HG421_RS08820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HG421_RS08825	ENOG4105D60	lipoprotein releasing system transmembrane protein
HG421_RS08835	ENOG410681N	tpr repeat protein
HG421_RS08860	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HG421_RS08870	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HG421_RS08885	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HG421_RS08890	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HG421_RS08895	ENOG4105C01	Dihydroxy-acid dehydratase
HG421_RS08900	ENOG4108UHU	Aldolase
HG421_RS08925	ENOG4105N7H	Cytochrome
HG421_RS08965	ENOG4105BZU	Histidine kinase
HG421_RS08970	ENOG4105BZM	domain protein
HG421_RS08990	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HG421_RS09000	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HG421_RS09035	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HG421_RS09040	ENOG4108Z6B	deaminase
HG421_RS09045	ENOG4105KST	dependent repressor
HG421_RS09050	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HG421_RS09060	ENOG4107SFI	Major Facilitator superfamily
HG421_RS09075	ENOG4105CHJ	isochorismatase hydrolase
HG421_RS09085	ENOG4105ENE	Histidine kinase
HG421_RS09090	ENOG4105WH1	Two component transcriptional regulator luxr family
HG421_RS09110	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG421_RS09115	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HG421_RS09120	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HG421_RS09130	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HG421_RS09135	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HG421_RS09150	ENOG4105CFV	Tetratricopeptide repeat protein
HG421_RS09165	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HG421_RS09170	ENOG4105CAT	Cytidine monophosphate kinase
HG421_RS09185	ENOG4105DWY	Agmatine deiminase
HG421_RS09215	ENOG4105DRS	transport system, permease
HG421_RS09220	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HG421_RS09225	ENOG4105XN3	extracellular solute-binding protein family 1
HG421_RS09250	ENOG4105K9H	YciI-like protein
HG421_RS09255	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HG421_RS09260	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HG421_RS09265	ENOG4105FE9	pseudouridine synthase
HG421_RS09285	ENOG4105CHM	Aminotransferase
HG421_RS09295	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HG421_RS09300	ENOG41060IM	Heme exporter protein
HG421_RS09310	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HG421_RS09315	ENOG4105DA4	cytochrome c-type biogenesis protein
HG421_RS09325	ENOG4105KWW	Biogenesis protein
HG421_RS09330	ENOG4108M1T	Cytochrome c-type biogenesis protein
HG421_RS09335	ENOG4105DWV	Homoserine O-trans-acetylase
HG421_RS09350	ENOG4108JJ8	(ABC) transporter
HG421_RS09355	ENOG4108JJ9	ABC, transporter
HG421_RS09360	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HG421_RS09365	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HG421_RS09390	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HG421_RS09420	ENOG4105CAS	nag kinase
HG421_RS09450	ENOG4105CDH	Citrulline--aspartate ligase
HG421_RS09455	ENOG4105DBV	ornithine carbamoyltransferase
HG421_RS09465	ENOG4105C8N	cysteinyl-tRNA synthetase
HG421_RS09470	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HG421_RS09490	ENOG4105CD3	dihydroorotase
HG421_RS09505	ENOG4105CPD	ethanolamine ammonia-lyase
HG421_RS09510	ENOG4107FQ9	ethanolamine ammonia-lyase
HG421_RS09540	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG421_RS09545	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HG421_RS09550	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HG421_RS09565	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HG421_RS09570	ENOG4105BZU	Histidine kinase
HG421_RS09585	ENOG4105ECY	inositol monophosphatase
HG421_RS09590	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG421_RS09605	ENOG4105C5H	ABC transporter
HG421_RS09610	ENOG4105C1J	atp-dependent rna helicase
HG421_RS09615	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HG421_RS09620	ENOG4105CNG	UPF0061 protein
HG421_RS09635	ENOG4105VEQ	Cold shock protein
HG421_RS09645	ENOG4108VWS	Yaeq family
HG421_RS09650	ENOG4105CBX	hi0933 family
HG421_RS09665	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HG421_RS09670	ENOG4105CHR	reductase
HG421_RS09690	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HG421_RS09695	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HG421_RS09705	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HG421_RS09710	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HG421_RS09725	ENOG4105E6M	Sulphatase-modifying factor protein
HG421_RS09735	ENOG4105DQE	DNA ligase
HG421_RS09750	ENOG4105DFP	Integrase
HG421_RS09790	ENOG4108V3W	Chemotaxis protein, CheW
HG421_RS09795	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS09800	ENOG4108VX5	3-methyladenine DNA glycosylase
HG421_RS09805	ENOG4107QRT	dEAD DEAH box helicase
HG421_RS09820	ENOG4105KB2	stringent starvation protein b
HG421_RS09825	ENOG4107MKT	Stringent starvation protein a
HG421_RS09830	ENOG4105EIX	cytochrome c1
HG421_RS09835	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG421_RS09840	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG421_RS09845	ENOG4105E4C	Lytic transglycosylase catalytic
HG421_RS09855	ENOG4108RXX	maleylacetoacetate isomerase
HG421_RS09865	ENOG4105C9A	Phoh family
HG421_RS09875	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HG421_RS09885	ENOG4108JU5	Magnesium and cobalt efflux protein
HG421_RS09905	ENOG4105D38	putrescine abc transporter
HG421_RS09910	ENOG4105F38	ABC transporter, permease
HG421_RS09920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HG421_RS09945	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG421_RS09960	ENOG4105CFQ	glutamine synthetase
HG421_RS09965	ENOG4105CJP	fad dependent oxidoreductase
HG421_RS09975	ENOG4105CSH	Transporter
HG421_RS09985	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HG421_RS09990	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HG421_RS10010	ENOG4106BRA	Membrane
HG421_RS10015	ENOG4105BZU	Histidine kinase
HG421_RS10020	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HG421_RS10025	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HG421_RS10080	ENOG4105C7I	Dehydrogenase
HG421_RS10090	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG421_RS10095	ENOG4105BZS	acriflavin resistance protein
HG421_RS10100	ENOG4108M60	Transcriptional regulator
HG421_RS10105	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HG421_RS10110	ENOG4105DE4	1-phosphofructokinase
HG421_RS10115	ENOG4105DM4	PTS System
HG421_RS10130	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS10175	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HG421_RS10180	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HG421_RS10185	ENOG4105VIE	preprotein translocase, subunit YajC
HG421_RS10195	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HG421_RS10245	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG421_RS10250	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HG421_RS10265	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HG421_RS10270	ENOG4106H78	methyltransferase
HG421_RS10275	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HG421_RS10340	ENOG4105F2I	Transposase
HG421_RS10365	ENOG4107QTZ	amino acid
HG421_RS10380	ENOG4105DC7	peptidase M24
HG421_RS10390	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HG421_RS10405	ENOG41080HI	glycine oxidase
HG421_RS10410	ENOG4105CTU	Proline racemase
HG421_RS10420	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HG421_RS10425	ENOG4105CEN	a g-specific adenine glycosylase
HG421_RS10450	ENOG4105QNF	Outer membrane lipoprotein
HG421_RS10465	ENOG4105CSU	acyl-Coa dehydrogenase
HG421_RS10475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HG421_RS10495	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HG421_RS10505	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HG421_RS10530	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
HG421_RS10540	ENOG4107Y2G	Glycosyl transferase (Group 1
HG421_RS10565	ENOG4105D3Q	Sugar transferase
HG421_RS10585	ENOG4105WJX	transcriptional regulator MERR family
HG421_RS10595	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HG421_RS10600	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HG421_RS10615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HG421_RS10620	ENOG4105C22	threonyL-tRNA synthetase
HG421_RS10625	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS10635	ENOG4107RBJ	symporter
HG421_RS10660	ENOG4105CG3	alpha amylase, catalytic region
HG421_RS10735	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
HG421_RS10755	ENOG4105CMA	conjugation trbi family protein
HG421_RS10785	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HG421_RS10830	ENOG4105EWT	decarboxylase family
HG421_RS10835	ENOG4108KPZ	tonB-dependent Receptor
HG421_RS10840	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HG421_RS10850	ENOG4105M2J	Glutaredoxin
HG421_RS10855	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG421_RS10860	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HG421_RS10865	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HG421_RS10875	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HG421_RS10885	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HG421_RS10895	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HG421_RS10900	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HG421_RS10905	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HG421_RS10910	ENOG4105CHV	Transcription elongation factor NusA
HG421_RS10915	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HG421_RS10925	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG421_RS10930	ENOG4105C8S	subunit m
HG421_RS10945	ENOG4105DF2	NADH dehydrogenase subunit j
HG421_RS10950	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG421_RS10955	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HG421_RS10960	ENOG4107R0R	NADH dehydrogenase subunit g
HG421_RS10965	ENOG4107QIZ	NADH dehydrogenase
HG421_RS10970	ENOG4105GKE	subunit e
HG421_RS10975	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HG421_RS10980	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HG421_RS10990	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HG421_RS11005	ENOG4105CP7	Triose-phosphate isomerase
HG421_RS11010	ENOG4105EMU	Dehydrogenase
HG421_RS11030	ENOG4105BZU	Histidine kinase
HG421_RS11045	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HG421_RS11065	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HG421_RS11075	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HG421_RS11080	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HG421_RS11095	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HG421_RS11100	ENOG4105C5I	Dehydrogenase
HG421_RS11105	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HG421_RS11110	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HG421_RS11120	ENOG4105DJ4	phosphatidylserine decarboxylase
HG421_RS11125	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
HG421_RS11130	ENOG4105D7A	ATP-binding protein
HG421_RS11145	ENOG4107VIJ	nudix hydrolase
HG421_RS11160	ENOG4108RRZ	Transcription elongation factor GreB
HG421_RS11165	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HG421_RS11190	ENOG4105DHP	deoxycytidine triphosphate deaminase
HG421_RS11195	ENOG4105D1F	ATP-binding protein
HG421_RS11215	ENOG4105C9K	Endothelin-converting enzyme 1
HG421_RS11235	ENOG4105DC8	reductase
HG421_RS11240	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HG421_RS11250	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HG421_RS11255	ENOG4105K4H	Nlp p60 protein
HG421_RS11260	ENOG4105K4H	Nlp p60 protein
HG421_RS11280	ENOG4105G6Z	alkaline phosphatase
HG421_RS11285	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HG421_RS11290	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HG421_RS11295	ENOG4105CTB	Polyprenyl synthetase
HG421_RS11310	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HG421_RS11320	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HG421_RS11330	ENOG4105QD6	exported protein
HG421_RS11335	ENOG4105C03	ribonuclease
HG421_RS11345	ENOG4105MPN	Membrane
HG421_RS11350	ENOG4108KPZ	tonB-dependent Receptor
HG421_RS11385	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HG421_RS11400	ENOG4105C8T	Leucyl-tRNA synthetase
HG421_RS11410	ENOG4107QR8	Thioredoxin
HG421_RS11420	ENOG4105WG9	Conserved Protein
HG421_RS11465	ENOG4105BZ1	(ABC) transporter
HG421_RS11480	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HG421_RS11505	ENOG4105FE9	pseudouridine synthase
HG421_RS11510	ENOG4105BZU	Histidine kinase
HG421_RS11585	ENOG4105UGU	tonB-dependent Receptor
HG421_RS11620	ENOG4105CF7	AraC family transcriptional regulator
HG421_RS11625	ENOG4105MYN	Zinc uptake regulation protein
HG421_RS11655	ENOG4105CT7	inner membrane cred family protein
HG421_RS11665	ENOG4105EB3	Histidine kinase
HG421_RS11670	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HG421_RS11675	ENOG4105D6S	protein involved in catabolism of external DNA
HG421_RS11700	ENOG4108JA2	transcriptioN-repair coupling factor
HG421_RS11735	ENOG4105CBS	Chea signal transduction histidine kinase
HG421_RS11740	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS11745	ENOG4108V3W	Chemotaxis protein, CheW
HG421_RS11750	ENOG4105BZU	Histidine kinase
HG421_RS11755	ENOG4105BZU	Histidine kinase
HG421_RS11760	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HG421_RS11765	ENOG4107RZC	phospholipase d
HG421_RS11770	ENOG4105C9K	Endothelin-converting enzyme 1
HG421_RS11780	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HG421_RS11785	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HG421_RS11790	ENOG4105EUB	pirin domain protein
HG421_RS11805	ENOG4105EUB	pirin domain protein
HG421_RS11815	ENOG4105D22	carbon starvation protein
HG421_RS11820	ENOG4105VCD	cytoplasmic protein
HG421_RS11855	ENOG4107XAN	XdhC and CoxI family
HG421_RS11860	ENOG4105C7W	Xanthine dehydrogenase
HG421_RS11865	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HG421_RS11870	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HG421_RS11885	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS11895	ENOG4105EAA	nucleoside
HG421_RS11935	ENOG4105EGS	Mechanosensitive ion channel
HG421_RS11955	ENOG4108UUM	single-stranded DNA-binding protein
HG421_RS11960	ENOG4105EAH	synthase
HG421_RS11970	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HG421_RS11985	ENOG4105CFH	Aspartokinase
HG421_RS11995	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HG421_RS12005	ENOG4108Z9K	Osmotically inducible protein
HG421_RS12015	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HG421_RS12020	ENOG4108UJU	UPF0301 protein
HG421_RS12030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG421_RS12045	ENOG4105CZX	twitching motility protein
HG421_RS12050	ENOG4105CZX	twitching motility protein
HG421_RS12055	ENOG4105DFA	alanine racemase domain protein
HG421_RS12060	ENOG4105II7	pyrroline-5-carboxylate reductase
HG421_RS12075	ENOG4108K5P	(LipO)protein
HG421_RS12095	ENOG4108Z0Z	intracellular protease Pfpi family
HG421_RS12115	ENOG4105C3K	feS assembly ATPase SufC
HG421_RS12120	ENOG4105JRK	feS assembly protein SufD
HG421_RS12125	ENOG4105C9B	Cysteine desulfurase
HG421_RS12130	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HG421_RS12135	ENOG4105VQD	rieske 2fe-2S domain-containing protein
HG421_RS12140	ENOG4108ESX	Receptor
HG421_RS12145	ENOG4107E2E	PKHD-type hydroxylase
HG421_RS12170	ENOG4105CJ2	(LipO)protein
HG421_RS12185	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HG421_RS12200	ENOG4105EHM	Aminoglycoside phosphotransferase
HG421_RS12205	ENOG4108S0S	Nucleotidyl transferase
HG421_RS12215	ENOG4105C02	permease
HG421_RS12225	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HG421_RS12240	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HG421_RS12260	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HG421_RS12270	ENOG4105C2X	Arabinose 5-phosphate isomerase
HG421_RS12275	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HG421_RS12285	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HG421_RS12290	ENOG4108IUZ	ABC transporter
HG421_RS12295	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG421_RS12300	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HG421_RS12305	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HG421_RS12315	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HG421_RS12325	ENOG41080Z8	PHOSPHOCARRIER protein
HG421_RS12330	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HG421_RS12335	ENOG4105CJW	magnesium transporter
HG421_RS12340	ENOG4107UWA	esterase
HG421_RS12345	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HG421_RS12350	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HG421_RS12355	ENOG4105C85	amino acid
HG421_RS12360	ENOG4108NFF	pectate lyase
HG421_RS12405	ENOG4105CUB	amino acid
HG421_RS12410	ENOG4108MHS	Lysyl endopeptidase
HG421_RS12420	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HG421_RS12450	ENOG4108Z4X	TRANSCRIPTIONal
HG421_RS12465	ENOG4106032	Glutathionylspermidine synthase
HG421_RS12490	ENOG4108P9J	Phage shock protein A
HG421_RS12505	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HG421_RS12510	ENOG4105D49	3-dehydroquinate synthase
HG421_RS12520	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HG421_RS12590	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HG421_RS12595	ENOG4105BZU	Histidine kinase
HG421_RS12600	ENOG4105BZU	Histidine kinase
HG421_RS12605	ENOG4105BZU	Histidine kinase
HG421_RS12610	ENOG4105BZU	Histidine kinase
HG421_RS12615	ENOG4108YYC	ycei family
HG421_RS12630	ENOG4105VEQ	Cold shock protein
HG421_RS12640	ENOG4105EJQ	L-serine dehydratase
HG421_RS12650	ENOG4105CFH	Aspartokinase
HG421_RS12655	ENOG4105C28	cystathionine
HG421_RS12660	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
HG421_RS12675	ENOG4108UT2	hemolysin iii
HG421_RS12680	ENOG41066T0	asmA family
HG421_RS12685	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HG421_RS12695	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HG421_RS12700	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HG421_RS12710	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS12715	ENOG4108IG5	Transcriptional regulator
HG421_RS12725	ENOG4107QPN	acyl-Coa dehydrogenase
HG421_RS12755	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HG421_RS12760	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HG421_RS12785	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HG421_RS12790	ENOG4107RK2	ADP-ribose diphosphatase NudE
HG421_RS12800	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HG421_RS12805	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HG421_RS12820	ENOG4105VRS	hydrolase family 18
HG421_RS12825	ENOG4105E2D	ec 3.2.1.52
HG421_RS12845	ENOG4105CWX	Alpha-1,2-mannosidase
HG421_RS12895	ENOG4105DZR	Type I site-specific deoxyribonuclease
HG421_RS12920	ENOG4106N3A	copper homeostasis protein cutc
HG421_RS12930	ENOG4105CP2	von willebrand factor, type a
HG421_RS12935	ENOG4105D9U	N-acetyltransferase
HG421_RS12955	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS12965	ENOG4105M3Z	response regulator
HG421_RS12970	ENOG4108UNF	response regulator
HG421_RS12975	ENOG4105D7Z	glutathione synthase
HG421_RS12985	ENOG41065RQ	ADP-ribosylation crystallin J1
HG421_RS12990	ENOG41072GX	Peptidase M22 Glycoprotease
HG421_RS12995	ENOG4105DVT	helicase
HG421_RS13005	ENOG4105BZ4	penicillin-binding protein
HG421_RS13020	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HG421_RS13025	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
HG421_RS13030	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HG421_RS13035	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
HG421_RS13045	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HG421_RS13065	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HG421_RS13075	ENOG4105CQ7	ATP-dependent helicase
HG421_RS13085	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HG421_RS13135	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HG421_RS13145	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HG421_RS13150	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HG421_RS13165	ENOG4105E02	MotA TolQ exbB proton channel
HG421_RS13170	ENOG4107YD3	Thioesterase
HG421_RS13175	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HG421_RS13185	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HG421_RS13190	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HG421_RS13195	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HG421_RS13200	ENOG4105CDY	transcriptional regulatory protein
HG421_RS13215	ENOG4105C9M	aspartyl-trna synthetase
HG421_RS13230	ENOG4108ISG	Major Facilitator
HG421_RS13245	ENOG4105HSS	phospholipase C
HG421_RS13255	ENOG4105ETT	transcriptional Regulator, LysR family
HG421_RS13260	ENOG4105C5H	ABC transporter
HG421_RS13265	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS13275	ENOG4107RNH	Outer membrane receptor FepA
HG421_RS13280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS13290	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HG421_RS13315	ENOG4105GAV	receptor
HG421_RS13320	ENOG4105CPF	Cell wall formation (By similarity)
HG421_RS13330	ENOG4105C6X	Major Facilitator
HG421_RS13340	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HG421_RS13360	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HG421_RS13385	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HG421_RS13395	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS13405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG421_RS13410	ENOG4105E2Y	ABC, transporter
HG421_RS13415	ENOG41082IR	Excinuclease ABC C subunit domain protein
HG421_RS13465	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS13470	ENOG4108K4C	ec 3.1.3.12
HG421_RS13475	ENOG4105BZP	glycoside hydrolase 15-related
HG421_RS13480	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HG421_RS13485	ENOG4105DZG	Dehydrogenase
HG421_RS13490	ENOG4105C8Q	Methyl-accepting chemotaxis
HG421_RS13495	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HG421_RS13510	ENOG4105C34	Pseudouridine synthase
HG421_RS13515	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG421_RS13520	ENOG4105C4K	Nad synthetase
HG421_RS13525	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HG421_RS13535	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HG421_RS13540	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HG421_RS13545	ENOG4107TUY	Histidine kinase
HG421_RS13550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG421_RS13555	ENOG4107QHF	type ii secretion system protein e
HG421_RS13560	ENOG4107QHF	type ii secretion system protein e
HG421_RS13565	ENOG4107QHF	type ii secretion system protein e
HG421_RS13570	ENOG4107QHF	type ii secretion system protein e
HG421_RS13575	ENOG4105KHS	type IV fimbrial pilin protein
HG421_RS13590	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HG421_RS13595	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HG421_RS13635	ENOG4105BZU	Histidine kinase
HG421_RS13640	ENOG4105ETX	regulatoR
HG421_RS13650	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG421_RS13695	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HG421_RS13720	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HG421_RS13730	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS13735	ENOG41065HY	1,4-beta-cellobiosidase
HG421_RS13760	ENOG4105EBR	Carboxylesterase
HG421_RS13765	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HG421_RS13770	ENOG4105BZG	amino acid carrier protein
HG421_RS13775	ENOG4105CD8	aminopeptidase N
HG421_RS13780	ENOG4105BZS	acriflavin resistance protein
HG421_RS13785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG421_RS13790	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HG421_RS13800	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HG421_RS13805	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HG421_RS13830	ENOG4105BZU	Histidine kinase
HG421_RS13835	ENOG4107R11	Transcriptional regulator
HG421_RS13855	ENOG4108UVJ	appr-1-p processing domain protein
HG421_RS13860	ENOG4107R1Y	fructose-bisphosphate aldolase
HG421_RS13865	ENOG4105CA9	Pyruvate kinase
HG421_RS13905	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HG421_RS13930	ENOG4107S76	domain protein
HG421_RS13935	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HG421_RS13940	ENOG4105E0C	molybdate abc transporter
HG421_RS13945	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HG421_RS13965	ENOG4105DHQ	Histidine kinase
HG421_RS13970	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG421_RS13980	ENOG4105CHR	reductase
HG421_RS13990	ENOG4108IQE	Amp-dependent synthetase and ligase
HG421_RS14015	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
HG421_RS14020	ENOG4105DR5	peptidase
HG421_RS14030	ENOG4105CHR	reductase
HG421_RS14035	ENOG4105CBN	LysR family transcriptional regulator
HG421_RS14040	ENOG4105CNM	Receptor
HG421_RS14045	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS14050	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HG421_RS14055	ENOG4105CK2	sodium dicarboxylate symporter
HG421_RS14070	ENOG4107QVM	von Willebrand factor, type A
HG421_RS14090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG421_RS14095	ENOG4105E4G	Type IV pilus
HG421_RS14120	ENOG4108JQC	penicillin-binding protein 1A
HG421_RS14135	ENOG4105BZN	citrate synthase
HG421_RS14150	ENOG4105CB5	ATP-dependent DNA helicase recG
HG421_RS14155	ENOG4105KME	endoribonuclease L-psp
HG421_RS14160	ENOG4108MA4	Peptidase M66
HG421_RS14175	ENOG4105F2I	Transposase
HG421_RS14180	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HG421_RS14190	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HG421_RS14195	ENOG4105DSJ	YicC domain protein
HG421_RS14200	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HG421_RS14205	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HG421_RS14210	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HG421_RS14215	ENOG4105CSA	Coproporphyrinogen iii oxidase
HG421_RS14240	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HG421_RS14245	ENOG4107RAQ	aminopeptidase
HG421_RS14250	ENOG4105E07	UPF0149 protein
HG421_RS14260	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HG421_RS14270	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HG421_RS14290	ENOG41063JG	Transcriptional regulator
HG421_RS14295	ENOG4105VCQ	rubredoxin
HG421_RS14300	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HG421_RS14310	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HG421_RS14315	ENOG41061ZR	Transcriptional regulator
HG421_RS14325	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG421_RS14360	ENOG4105C8Y	Acetylornithine aminotransferase
HG421_RS14385	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HG421_RS14390	ENOG4105FFC	UPF0187 protein
HG421_RS14400	ENOG4105DFU	Cell wall formation (By similarity)
HG421_RS14405	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HG421_RS14430	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HG421_RS14440	ENOG4105F0N	pyrophosphate phospho-hydrolase
HG421_RS14455	ENOG4105ECQ	AraC Family Transcriptional Regulator
HG421_RS14460	ENOG4108M3R	transcriptional activator CadC
HG421_RS14470	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HG421_RS14480	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG421_RS14500	ENOG4105C7B	Threonine dehydratase
HG421_RS14505	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HG421_RS14515	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG421_RS14520	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG421_RS14525	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG421_RS14530	ENOG4108MP6	LysR family Transcriptional regulator
HG421_RS14535	ENOG4105BZU	Histidine kinase
HG421_RS14545	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HG421_RS14550	ENOG4105DFG	type I secretion outer membrane protein
HG421_RS14555	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HG421_RS14560	ENOG4105D1S	lipid A biosynthesis
HG421_RS14600	ENOG4105C6K	Malic enzyme
HG421_RS14630	ENOG4105CPC	Aldo Keto reductase
HG421_RS14640	ENOG4105WH1	Two component transcriptional regulator luxr family
HG421_RS14645	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
HG421_RS14650	ENOG4105DHQ	Histidine kinase
HG421_RS14665	ENOG4105D4T	Citrate transporter
HG421_RS14670	ENOG4105CHR	reductase
HG421_RS14675	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS14690	ENOG4107QW3	Sucrose phosphorylase
HG421_RS14705	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HG421_RS14710	ENOG4105CHM	Aminotransferase
HG421_RS14745	ENOG41069H0	dihydroorotase EC 3.5.2.3
HG421_RS14750	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HG421_RS14775	ENOG4108RMV	DegV Family
HG421_RS14790	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HG421_RS14795	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HG421_RS14805	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
HG421_RS14820	ENOG4105DUM	transcriptional regulator, lysR family
HG421_RS14840	ENOG4105JJR	Histidine kinase
HG421_RS14860	ENOG4106RE7	Cytochrome
HG421_RS14865	ENOG4108Z33	Thiol disulfide Interchange Protein
HG421_RS14870	ENOG4108Z33	Thiol disulfide Interchange Protein
HG421_RS14880	ENOG4105C94	Transporter
HG421_RS14885	ENOG4105C26	Dehydrogenase
HG421_RS14890	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HG421_RS14895	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG421_RS14920	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HG421_RS14935	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HG421_RS14950	ENOG4105DHJ	ABC, transporter
HG421_RS14955	ENOG4108SNX	Mammalian cell entry related domain protein
HG421_RS14970	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HG421_RS14985	ENOG4107QKV	phosphomannomutase
HG421_RS15000	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HG421_RS15005	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HG421_RS15020	ENOG4105BZJ	Electron transfer flavoprotein
HG421_RS15025	ENOG4105C10	Electron transfer flavoprotein
HG421_RS15035	ENOG4105CKK	Glycosyl transferase, family 2
HG421_RS15055	ENOG4105FAW	cDP-glucose 4,6-dehydratase
HG421_RS15060	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HG421_RS15065	ENOG4105CGN	Glycosyl transferase (Group 1
HG421_RS15075	ENOG4105EY8	ABC transporter
HG421_RS15085	ENOG4107STW	synthase
HG421_RS15090	ENOG4105C28	cystathionine
HG421_RS15115	ENOG4105CZX	twitching motility protein
HG421_RS15120	ENOG4108RXX	maleylacetoacetate isomerase
HG421_RS15135	ENOG4105C1J	atp-dependent rna helicase
HG421_RS15140	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HG421_RS15150	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HG421_RS15165	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG421_RS15170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG421_RS15175	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HG421_RS15220	ENOG4105DGW	oligopeptidase A
HG421_RS15225	ENOG4105C6T	cysteine synthase
HG421_RS15260	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HG421_RS15270	ENOG4105C19	ABC transporter
HG421_RS15280	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HG421_RS15295	ENOG4105BZU	Histidine kinase
HG421_RS15300	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HG421_RS15315	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HG421_RS15320	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HG421_RS15325	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HG421_RS15335	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG421_RS15345	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG421_RS15350	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
HG421_RS15365	ENOG4105CI2	imidazolone-5-propionate hydrolase
HG421_RS15370	ENOG4107QN2	dihydrolipoyl dehydrogenase
HG421_RS15380	ENOG4107QSN	dihydrolipoamide acetyltransferase
HG421_RS15405	ENOG4105D01	(LipO)protein
HG421_RS15410	ENOG4108UMI	ABC transporter, permease
HG421_RS15415	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HG421_RS15420	ENOG4108EHX	EamA-like transporter family
HG421_RS15425	ENOG4108VPT	UPF0234 protein
HG421_RS15435	ENOG4105BZU	Histidine kinase
HG421_RS15450	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HG421_RS15455	ENOG4107YBY	Hydrolase
HG421_RS15460	ENOG4105I08	Pseudouridine synthase
HG421_RS15465	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HG421_RS15485	ENOG4105BZU	Histidine kinase
HG421_RS15510	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HG421_RS15515	ENOG4105EW9	transcriptional regulator AsnC family
HG421_RS15530	ENOG4107RD7	Flagellar Motor Protein, MotA
HG421_RS15535	ENOG4105ER2	Ompa motb domain protein
HG421_RS15565	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HG421_RS15580	ENOG4105E3A	(ABC) transporter
HG421_RS15585	ENOG4105DA5	(ABC) transporter
HG421_RS15590	ENOG4105EEQ	Na H antiporter
HG421_RS15600	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HG421_RS15610	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HG421_RS15625	ENOG4105CPC	Aldo Keto reductase
HG421_RS15635	ENOG4105C9K	Endothelin-converting enzyme 1
HG421_RS15650	ENOG4107QTZ	amino acid
HG421_RS15660	ENOG4108VAC	response regulator
HG421_RS15665	ENOG4105C2F	Histidine kinase
HG421_RS15680	ENOG4108Z9Z	response to DNA damage stimulus
HG421_RS15685	ENOG4105WEF	catalase
HG421_RS15695	ENOG4105BZU	Histidine kinase
HG421_RS15710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG421_RS15720	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HG421_RS15725	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HG421_RS15740	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HG421_RS15750	ENOG4105E2A	Dehydrogenase
HG421_RS15825	ENOG4105CMQ	Chloride channel
HG421_RS15830	ENOG4105CC0	LysR family Transcriptional regulator
HG421_RS15835	ENOG4105CHR	reductase
HG421_RS15840	ENOG4105D3W	isochorismatase
HG421_RS15885	ENOG4105BZU	Histidine kinase
HG421_RS16070	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG421_RS16075	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HG421_RS16085	ENOG4108Z7F	N-acetyltransferase
HG421_RS16090	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HG421_RS16110	ENOG4106WTF	Glycosyl transferase, family 2
HG421_RS16125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HG421_RS16130	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HG421_RS16135	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HG421_RS16140	ENOG4108WZM	domain protein
HG421_RS16145	ENOG4105C79	DNA protecting protein DprA
HG421_RS16165	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HG421_RS16185	ENOG4107ZQV	short-chain dehydrogenase reductase
HG421_RS16195	ENOG4105D07	Signal peptide peptidase, SppA
HG421_RS16200	ENOG4107QI1	Mate efflux family protein
HG421_RS16220	ENOG4105C25	Primosomal protein n'
HG421_RS16225	ENOG4108TGY	Glutathione S-transferase
HG421_RS16245	ENOG4105EN6	Membrane
HG421_RS16250	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG421_RS16255	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HG421_RS16260	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HG421_RS16265	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HG421_RS16270	ENOG4105CAK	Cell division ATP-binding protein ftsE
HG421_RS16285	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HG421_RS16290	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HG421_RS16295	ENOG4108PZW	LysR family Transcriptional regulator
HG421_RS16305	ENOG4105E9K	Isocitrate dehydrogenase
HG421_RS16320	ENOG4105FB9	CRISPR-associated protein
HG421_RS16340	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HG421_RS16345	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HG421_RS16365	ENOG4105CH2	amidohydrolase
HG421_RS16370	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HG421_RS16375	ENOG4105BZS	acriflavin resistance protein
HG421_RS16385	ENOG4105E32	cytoplasmic protein
HG421_RS16425	ENOG4108UQS	dipeptidase
HG421_RS16430	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HG421_RS16440	ENOG4105DTQ	mandelate racemase muconate lactonizing
HG421_RS16450	ENOG4105D5Q	Arginine ornithine antiporter
HG421_RS16465	ENOG4108Z12	YiaAB two helix domain-containing protein
HG421_RS16475	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HG421_RS16480	ENOG4107ZVW	dihydroneopterin aldolase
HG421_RS16485	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HG421_RS16495	ENOG4105KTH	gatB Yqey
HG421_RS16500	ENOG4107S2Z	UPF0761 membrane protein
HG421_RS16505	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HG421_RS16515	ENOG4105DHU	Bile acid
HG421_RS16525	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HG421_RS16550	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HG421_RS16555	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HG421_RS16565	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HG421_RS16575	ENOG4105C26	Dehydrogenase
HG421_RS16610	ENOG4105DR5	peptidase
HG421_RS16625	ENOG4105EYM	Major Facilitator superfamily
HG421_RS16630	ENOG4105CGK	Exodeoxyribonuclease III
HG421_RS16645	ENOG4107QJE	Chromosome Partitioning Protein
HG421_RS16650	ENOG4105FA0	parb-like partition protein
HG421_RS16665	ENOG4105CKK	Glycosyl transferase, family 2
HG421_RS16680	ENOG4107QKV	phosphomannomutase
HG421_RS16685	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HG421_RS16690	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HG421_RS16700	ENOG4105C75	arginyL-tRNA synthetase
HG421_RS16715	ENOG4105EMU	Dehydrogenase
HG421_RS16720	ENOG4105EXC	Acyl-transferase
HG421_RS16730	ENOG4105CEY	Amp-dependent synthetase and ligase
HG421_RS16740	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HG421_RS16745	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HG421_RS16760	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
HG421_RS16765	ENOG4108YZA	Nitrogen regulatory protein pii
HG421_RS16770	ENOG4105W0Z	cytoplasmic protein
HG421_RS16775	ENOG4105C0P	Mg chelatase subunit ChlI
HG421_RS16815	ENOG41066DG	(EAL) domain protein
HG421_RS16830	ENOG4105EJ2	Transcriptional regulator
HG421_RS16865	ENOG4105ECP	epimerase
HG421_RS16880	ENOG4105C0H	protease
HG421_RS16900	ENOG4105DSF	transport protein
HG421_RS16910	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HG421_RS16915	ENOG4107VGR	Catalase
HG421_RS16930	ENOG4108S01	response regulator
HG421_RS16935	ENOG4108ZGX	Histidine kinase
HG421_RS16940	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HG421_RS16945	ENOG4105C19	ABC transporter
HG421_RS16970	ENOG4105FDR	Membrane
HG421_RS16990	ENOG4105C31	Tryptophanyl-tRNA synthetase
HG421_RS16995	ENOG4105VDW	Csbd family
HG421_RS17035	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HG421_RS17055	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HG421_RS17080	ENOG4105EB3	Histidine kinase
HG421_RS17085	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG421_RS17095	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG421_RS17170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG421_RS17195	ENOG4105CH6	catalase
HG421_RS17200	ENOG4105DVT	helicase
HG421_RS17210	ENOG4105E2X	shikimate dehydrogenase
HG421_RS17225	ENOG4105D52	delta-aminolevulinic acid dehydratase
HG421_RS17260	ENOG4105CYM	Glutathione S-transferase
HG421_RS17305	ENOG4108IUW	ABC transporter
HG421_RS17315	ENOG4105VZ8	Transcriptional regulator
HG421_RS17345	ENOG4105E0K	tonB-dependent siderophore receptor
HG421_RS17355	ENOG4105ECQ	AraC Family Transcriptional Regulator
HG421_RS17360	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HG421_RS17365	ENOG4105DA5	(ABC) transporter
HG421_RS17370	ENOG4105E3A	(ABC) transporter
HG421_RS17375	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HG421_RS17415	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HG421_RS17420	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HG421_RS17430	ENOG4105CD5	CoA-binding domain protein
HG421_RS17435	ENOG4105CJW	magnesium transporter
HG421_RS17445	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HG421_RS17450	ENOG4105BZP	glycoside hydrolase 15-related
HG421_RS17470	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG421_RS17480	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HG421_RS17495	ENOG4105C2D	reductase
HG421_RS17520	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HG421_RS17525	ENOG4105E9Q	Acyl-transferase
HG421_RS17535	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HG421_RS17540	ENOG4105P52	geranylgeranyl reductase
HG421_RS17560	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS17595	ENOG4105DIK	(ABC) transporter
HG421_RS17635	ENOG4105C2M	dna polymerase I
HG421_RS17660	ENOG4107TPY	serine threonine protein kinase
HG421_RS17665	ENOG4108ZF3	Phosphatase
HG421_RS17710	ENOG4105CS6	Rhs element vgr protein
HG421_RS17725	ENOG4105D9P	serine threonine protein kinase
HG421_RS17775	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG421_RS17800	ENOG4108WC9	type VI secretion system effector, hcp1 family
HG421_RS17835	ENOG4105C4R	Atp-dependent dna helicase
HG421_RS17845	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HG421_RS17850	ENOG4105DUM	transcriptional regulator, lysR family
HG421_RS17855	ENOG4105JSC	dimethylmenaquinone methyltransferase
HG421_RS17865	ENOG4105KHM	amidohydrolase 2
HG421_RS17910	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HG421_RS17945	ENOG4107QN1	sodium solute
HG421_RS18010	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HG421_RS18015	ENOG4105ERH	Fumarylacetoacetate hydrolase
HG421_RS18020	ENOG4105DIA	mandelate racemase muconate lactonizing
HG421_RS18025	ENOG4105QJH	Domain of unknown function (DUF718)
HG421_RS18030	ENOG4105EDR	glucose galactose transporter
HG421_RS18035	ENOG4108K2P	TRANSCRIPTIONal
HG421_RS18040	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HG421_RS18045	ENOG4105BZU	Histidine kinase
HG421_RS18050	ENOG4105E2V	Glycosyltransferase 36
HG421_RS18055	ENOG4105CT4	transporter
HG421_RS18060	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HG421_RS18090	ENOG4105F7F	Chaperone
HG421_RS18100	ENOG4105MA0	exported protein
HG421_RS18105	ENOG4105CFU	surface antigen
HG421_RS18110	ENOG4105D05	Receptor
HG421_RS18115	ENOG4107RDJ	Sulfotransferase
HG421_RS18120	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HG421_RS18125	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HG421_RS18130	ENOG4107QHF	type ii secretion system protein e
HG421_RS18135	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG421_RS18145	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HG421_RS18150	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HG421_RS18170	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HG421_RS18175	ENOG4108YIQ	Alpha beta hydrolase
HG421_RS18185	ENOG4105DH7	May be involved in recombination (By similarity)
HG421_RS18190	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HG421_RS18195	ENOG4105C93	Xylose Isomerase
HG421_RS18200	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS18205	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
HG421_RS18215	ENOG4105CXK	mandelate racemase muconate lactonizing
HG421_RS18230	ENOG4105DEI	Mannitol dehydrogenase
HG421_RS18290	ENOG4105D2H	Uronic isomerase
HG421_RS18310	ENOG4105CT4	transporter
HG421_RS18315	ENOG4105DT9	hydrolase family 43
HG421_RS18350	ENOG4105E55	glycerol-3-phosphate acyltransferase
HG421_RS18360	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS18375	ENOG4105QV4	Tryptophan halogenase
HG421_RS18385	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HG421_RS18390	ENOG4108YXG	UPF0502 protein
HG421_RS18395	ENOG4108428	Inherit from COG: -acetyltransferase
HG421_RS18400	ENOG4105C4R	Atp-dependent dna helicase
HG421_RS18405	ENOG4107104	thymidine kinase
HG421_RS18410	ENOG4105BZU	Histidine kinase
HG421_RS18415	ENOG4105DJ9	glucan biosynthesis protein
HG421_RS18425	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HG421_RS18455	ENOG4105DKK	Benzoate
HG421_RS18475	ENOG4105DSB	aldose 1-epimerase
HG421_RS18490	ENOG4105EJ9	Membrane
HG421_RS18520	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HG421_RS18525	ENOG4105EUJ	GTP cyclohydrolase i
HG421_RS18535	ENOG4105ZQC	membrane protein AaeX
HG421_RS18540	ENOG4105Y49	secretion protein, HlyD family
HG421_RS18550	ENOG4105DR8	Membrane
HG421_RS18555	ENOG4105CSH	Transporter
HG421_RS18560	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HG421_RS18685	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HG421_RS18690	ENOG41080ET	plasmid maintenance system killer protein
HG421_RS18700	ENOG4107QKA	exodeoxyribonuclease V beta
HG421_RS18705	ENOG4105DSY	exodeoxyribonuclease V, gamma
HG421_RS18740	ENOG4105DHJ	ABC, transporter
HG421_RS18745	ENOG4105CY3	ABC transporter, permease
HG421_RS18750	ENOG4107PE3	Mammalian cell entry related domain protein
HG421_RS18765	ENOG410903C	(LipO)protein
HG421_RS18775	ENOG4108V06	Glutathione peroxidase
HG421_RS18810	ENOG4105CUB	amino acid
HG421_RS18815	ENOG4105CWX	Alpha-1,2-mannosidase
HG421_RS18825	ENOG4105BZU	Histidine kinase
HG421_RS18830	ENOG4105BZW	Glycerate kinase
HG421_RS18855	ENOG4105DR4	Methyltransferase
HG421_RS18860	ENOG4105DU1	integral membrane protein, terc
HG421_RS18870	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HG421_RS18890	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HG421_RS18910	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HG421_RS18915	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HG421_RS18920	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG421_RS18930	ENOG4108K0D	peptidase, M48
HG421_RS18975	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HG421_RS18990	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HG421_RS19010	ENOG4105CN1	protease
HG421_RS19015	ENOG41063SB	peptidase
HG421_RS19025	ENOG4107VAM	peptidase, m28
HG421_RS19050	ENOG4105DQ4	alcohol dehydrogenase
HG421_RS19055	ENOG4105BZ8	glutamate synthase
HG421_RS19060	ENOG4105CBC	glutamate synthase
HG421_RS19120	ENOG4108I5C	dEAD DEAH box helicase
HG421_RS19125	ENOG4108UT2	hemolysin iii
HG421_RS19150	ENOG4105CYM	Glutathione S-transferase
HG421_RS19160	ENOG4105HEI	LysR family (Transcriptional regulator
HG421_RS19165	ENOG4105CHR	reductase
HG421_RS19235	ENOG4105D4Y	metalloprotease
HG421_RS19255	ENOG4105C02	permease
HG421_RS19265	ENOG4105K63	Thioredoxin
HG421_RS19270	ENOG4105CSH	Transporter
HG421_RS19315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG421_RS19370	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HG421_RS19375	ENOG4105CGF	Aromatic amino acid aminotransferase
HG421_RS19380	ENOG4105CHB	tonB-dependent Receptor
HG421_RS19385	ENOG4105C26	Dehydrogenase
HG421_RS19415	ENOG4105DQE	DNA ligase
HG421_RS19420	ENOG4105DMF	Dehydrogenase
HG421_RS19440	ENOG4105BZU	Histidine kinase
HG421_RS19445	ENOG4105WH1	Two component transcriptional regulator luxr family
HG421_RS19455	ENOG4108YAB	Invasion protein
HG421_RS19460	ENOG4105RKW	reductase (By
HG421_RS19575	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HG421_RS19580	ENOG4105CG3	alpha amylase, catalytic region
HG421_RS19615	ENOG4107TDE	lipolytic protein G-D-S-L family
HG421_RS19620	ENOG4105EBR	Carboxylesterase
HG421_RS19635	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HG421_RS19645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HG421_RS19650	ENOG4105DSG	hydrolase family 43
HG421_RS19655	ENOG4105ETE	Transcriptional regulator (LacI family
HG421_RS19660	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HG421_RS19665	ENOG4105CHR	reductase
HG421_RS19675	ENOG4107TDE	lipolytic protein G-D-S-L family
HG421_RS19685	ENOG4105MIR	Phenylalanine 4-monooxygenase
HG421_RS19690	ENOG4108YXU	transcriptional regulator AsnC family
HG421_RS19695	ENOG4105D78	K07001 NTE family protein
HG421_RS19705	ENOG4105DKW	ABC transporter
HG421_RS19715	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HG421_RS19720	ENOG4108IJ8	ABC transporter
HG421_RS19725	ENOG4105E90	ABC transporter
HG421_RS19740	ENOG41067HS	methyltransferase
HG421_RS19750	ENOG4105CAF	HipA N-terminal domain protein
HG421_RS19790	ENOG4105D1F	ATP-binding protein
HG421_RS19795	ENOG4105M4E	phosphohistidine phosphatase, SixA
HG421_RS19805	ENOG4107RZC	phospholipase d
HG421_RS19810	ENOG4105KA0	thioesterase Superfamily protein
HG421_RS19845	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HG421_RS19850	ENOG4105C5F	glutamine synthetase
HG421_RS19860	ENOG4105BZU	Histidine kinase
HG421_RS19865	ENOG4105CUX	Signal transduction histidine kinase
HG421_RS19870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG421_RS19875	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG421_RS19880	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG421_RS19885	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HG421_RS19895	ENOG4105CHU	acetyl-coa acetyltransferase
HG421_RS19935	ENOG4107YZP	Rhodanese domain protein
HG421_RS19940	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HG421_RS19945	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HG421_RS20005	ENOG4105D00	flagellar biosynthetic protein flhB
HG421_RS20010	ENOG4105D7B	Flagellar biosynthesis protein flha
HG421_RS20015	ENOG4108JQA	flagellar
HG421_RS20020	ENOG4105CGA	flagellar basal-body rod protein FlgG
HG421_RS20030	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG421_RS20035	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG421_RS20045	ENOG4108ZC9	flagellar basal-body rod protein flgc
HG421_RS20050	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HG421_RS20055	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HG421_RS20085	ENOG410822I	Flagellar hook capping protein
HG421_RS20090	ENOG4105BZE	flagellar hook protein, FlgE
HG421_RS20100	ENOG4105DD5	Flagellar motor switch protein
HG421_RS20110	ENOG4105CN7	Flagellar biosynthetic protein FliP
HG421_RS20120	ENOG4105C7K	acetolactate synthase
HG421_RS20125	ENOG4108TQ9	Histidine kinase
HG421_RS20150	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HG421_RS20165	ENOG4105E2T	synthase III
HG421_RS20170	ENOG4107R3N	Filamentation induced by cAMP protein fic
HG421_RS20175	ENOG4108J2P	Alpha beta hydrolase fold
HG421_RS20180	ENOG4105PI0	Ferredoxin
HG421_RS20185	ENOG410680H	amp-dependent synthetase and ligase
HG421_RS20190	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HG421_RS20205	ENOG4105CPF	Cell wall formation (By similarity)
HG421_RS20215	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HG421_RS20220	ENOG4105DR9	pseudouridine synthase
HG421_RS20230	ENOG4108YZN	class I peptide chain release factor
HG421_RS20245	ENOG4105D44	asparaginase
HG421_RS20250	ENOG4105DGW	oligopeptidase A
HG421_RS20310	ENOG4107R11	Transcriptional regulator
HG421_RS20315	ENOG4107QP3	malate synthase g
HG421_RS20325	ENOG4105BZU	Histidine kinase
HG421_RS20355	ENOG4107QX3	carboxylase
HG421_RS20360	ENOG4105C1G	acyl-Coa dehydrogenase
HG421_RS20430	ENOG4108TZV	Membrane
HG421_RS20440	ENOG4105D6Z	AFG1 family ATPase
HG421_RS20445	ENOG4105K56	Transcriptional regulator
HG421_RS20450	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HG421_RS20465	ENOG4105CV8	reductase
HG421_RS20470	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG421_RS20475	ENOG4105CPC	Aldo Keto reductase
HG421_RS20485	ENOG4108R99	pseudouridine synthase
HG421_RS20495	ENOG4105CQ7	ATP-dependent helicase
HG421_RS20500	ENOG4108W15	Protein of unknown function (DUF1456)
HG421_RS20510	ENOG4105E1J	oxidoreductase
HG421_RS20530	ENOG4105C5R	Aminotransferase
HG421_RS20550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG421_RS20570	ENOG4105C7N	Xanthine uracil vitamin C permease
HG421_RS20590	ENOG4105ETT	transcriptional Regulator, LysR family
HG421_RS20605	ENOG4105F8V	Hydrolase, tatD family
HG421_RS20620	ENOG4106NZI	LysR family Transcriptional regulator
HG421_RS20625	ENOG4105D94	Major Facilitator Superfamily
HG421_RS20630	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HG421_RS20635	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG421_RS20660	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HG421_RS20675	ENOG4105DZ2	Transcriptional regulator
HG421_RS20680	ENOG4108UZX	fmn reductase
HG421_RS20700	ENOG4105ECR	NmrA family
HG421_RS20760	ENOG4105C01	Dihydroxy-acid dehydratase
HG421_RS20775	ENOG4108Z0R	Transferase
HG421_RS20785	ENOG4105CPI	Metal Dependent Phosphohydrolase
HG421_RS20825	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HG421_RS20830	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HG421_RS20835	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HG421_RS20840	ENOG4105E98	transcriptional regulator DeoR family
HG421_RS20870	ENOG4105CHU	acetyl-coa acetyltransferase
HG421_RS20885	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HG421_RS20890	ENOG4105F2Z	3-oxoadipate enol-lactonase
HG421_RS20895	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HG421_RS20905	ENOG4107HP6	Transcriptional regulator
HG421_RS20930	ENOG4105MH3	Protein of unknown function (DUF2490)
HG421_RS20935	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HG421_RS20940	ENOG4105VNT	transposase (IS4 family) protein
HG421_RS20950	ENOG4105C7B	Threonine dehydratase
HG421_RS20980	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HG421_RS20990	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HG421_RS20995	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HG421_RS21000	ENOG41081UC	Inherit from COG: Competence protein
HG421_RS21005	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HG421_RS21020	ENOG4105EGS	Mechanosensitive ion channel