locus-tag	class	description
C1H20_RS00020	COG0187	DNA topoisomerase II activity
C1H20_RS00030	COG0501	Belongs to the peptidase M48B family
C1H20_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1H20_RS00110	COG0793	Belongs to the peptidase S41A family
C1H20_RS00120	COG4942	peptidase
C1H20_RS00130	COG2234	aminopeptidase activity
C1H20_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C1H20_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C1H20_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C1H20_RS00160	COG1064	alcohol dehydrogenase
C1H20_RS00175	COG0493	'glutamate synthase
C1H20_RS00180	COG0070	glutamate synthase
C1H20_RS00180	COG0067	glutamate synthase
C1H20_RS00180	COG0069	glutamate synthase activity
C1H20_RS00195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C1H20_RS00205	COG1741	Belongs to the pirin family
C1H20_RS00210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1H20_RS00230	COG0583	DNA-binding transcription factor activity
C1H20_RS00295	COG1205	dead DEAH box helicase
C1H20_RS00295	COG1111	helicase
C1H20_RS00315	COG1272	protein, Hemolysin III
C1H20_RS00390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1H20_RS00395	COG3237	CsbD-like
C1H20_RS00440	COG0628	permease
C1H20_RS00445	COG0657	acetylesterase activity
C1H20_RS00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1H20_RS00460	COG0477	Major facilitator Superfamily
C1H20_RS00500	COG0714	Associated with various cellular activities
C1H20_RS00545	COG4772	TonB-dependent receptor
C1H20_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
C1H20_RS00585	COG3039	Transposase
C1H20_RS00615	COG3710	Transcriptional regulator
C1H20_RS00635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1H20_RS00720	COG0366	Alpha amylase catalytic
C1H20_RS00725	COG0366	Alpha amylase catalytic
C1H20_RS00775	COG2755	lipolytic protein G-D-S-L family
C1H20_RS00785	COG0657	acetylesterase activity
C1H20_RS00785	COG2755	lipolytic protein G-D-S-L family
C1H20_RS00795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1H20_RS00810	COG3507	Belongs to the glycosyl hydrolase 43 family
C1H20_RS00815	COG1609	Transcriptional regulator
C1H20_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS00835	COG2755	lipolytic protein G-D-S-L family
C1H20_RS00845	COG3186	Phenylalanine-4-hydroxylase
C1H20_RS00850	COG1522	sequence-specific DNA binding
C1H20_RS00870	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1H20_RS00880	COG1119	ATPase activity
C1H20_RS00895	COG0517	IMP dehydrogenase activity
C1H20_RS00895	COG1125	glycine betaine transport
C1H20_RS00910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1H20_RS00915	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C1H20_RS00945	COG0489	protein tyrosine kinase activity
C1H20_RS00950	COG0588	phosphoglycerate mutase activity
C1H20_RS00960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS00985	COG1881	PFAM PEBP family protein
C1H20_RS01005	COG0174	glutamine synthetase
C1H20_RS01010	COG0347	Belongs to the P(II) protein family
C1H20_RS01015	COG0004	ammonium transporteR
C1H20_RS01020	COG3852	Histidine kinase
C1H20_RS01025	COG2204	response regulator
C1H20_RS01035	COG2032	superoxide dismutase activity
C1H20_RS01040	COG2032	superoxide dismutase activity
C1H20_RS01045	COG0346	lactoylglutathione lyase activity
C1H20_RS01055	COG0183	Belongs to the thiolase family
C1H20_RS01095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1H20_RS01115	COG0028	Belongs to the TPP enzyme family
C1H20_RS01130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1H20_RS01145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1H20_RS01150	COG3177	Filamentation induced by cAMP protein fic
C1H20_RS01155	COG0596	Alpha beta hydrolase
C1H20_RS01160	COG0727	PFAM Uncharacterised protein family (UPF0153)
C1H20_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
C1H20_RS01175	COG0745	RESPONSE REGULATOR receiver
C1H20_RS01190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1H20_RS01205	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1H20_RS01220	COG0564	pseudouridine synthase activity
C1H20_RS01245	COG0339	signal peptide processing
C1H20_RS01275	COG0583	DNA-binding transcription factor activity
C1H20_RS01280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1H20_RS01285	COG2224	Isocitrate lyase
C1H20_RS01315	COG4770	biotin carboxylase activity
C1H20_RS01320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1H20_RS01325	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS01390	COG0697	spore germination
C1H20_RS01400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1H20_RS01410	COG1846	Transcriptional regulator
C1H20_RS01415	COG1764	response to oxidative stress
C1H20_RS01455	COG0656	L-ascorbic acid biosynthetic process
C1H20_RS01460	COG2130	NADP-dependent
C1H20_RS01475	COG1187	pseudouridine synthase activity
C1H20_RS01485	COG1643	Atp-dependent helicase
C1H20_RS01490	COG0840	transmembrane signaling receptor activity
C1H20_RS01495	COG4807	Protein conserved in bacteria
C1H20_RS01500	COG2351	hydroxyisourate hydrolase activity
C1H20_RS01505	COG2072	flavoprotein involved in K transport
C1H20_RS01525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1H20_RS01555	COG3568	Endonuclease Exonuclease Phosphatase
C1H20_RS01560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS01575	COG1957	nucleoside hydrolase
C1H20_RS01585	COG2252	PERMEase
C1H20_RS01605	COG0084	hydrolase, TatD family'
C1H20_RS01615	COG0583	DNA-binding transcription factor activity
C1H20_RS01620	COG2814	Major facilitator Superfamily
C1H20_RS01640	COG1902	pentaerythritol trinitrate reductase activity
C1H20_RS01665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1H20_RS01670	COG0583	DNA-binding transcription factor activity
C1H20_RS01695	COG0702	epimerase
C1H20_RS01700	COG1733	regulation of RNA biosynthetic process
C1H20_RS01710	COG0840	transmembrane signaling receptor activity
C1H20_RS01855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1H20_RS01915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1H20_RS01940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1H20_RS01945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1H20_RS01955	COG3485	protocatechuate 3,4-dioxygenase
C1H20_RS01960	COG3485	protocatechuate 3,4-dioxygenase
C1H20_RS01970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1H20_RS01975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1H20_RS01985	COG1414	Transcriptional regulator
C1H20_RS01995	COG0657	acetylesterase activity
C1H20_RS02020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1H20_RS02070	COG1040	competence protein
C1H20_RS02085	COG0582	viral genome integration into host DNA
C1H20_RS02095	COG4774	siderophore transport
C1H20_RS02105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1H20_RS02125	COG4206	TonB-dependent receptor
C1H20_RS02145	COG3264	Mechanosensitive ion channel
C1H20_RS02145	COG1511	domain protein
C1H20_RS02160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1H20_RS02165	COG2354	Protein conserved in bacteria
C1H20_RS02170	COG1649	PFAM Uncharacterised BCR, COG1649
C1H20_RS02190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1H20_RS02215	COG0702	epimerase
C1H20_RS02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1H20_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS02275	COG0513	Belongs to the DEAD box helicase family
C1H20_RS02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1H20_RS02310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1H20_RS02325	COG3104	oligopeptide transport
C1H20_RS02345	COG2852	Protein conserved in bacteria
C1H20_RS02370	COG1320	monovalent cation:proton antiporter activity
C1H20_RS02375	COG2212	antiporter activity
C1H20_RS02385	COG0651	ATP synthesis coupled electron transport
C1H20_RS02390	COG1006	Multisubunit Na H antiporter MnhC subunit
C1H20_RS02395	COG2111	Na H antiporter
C1H20_RS02395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1H20_RS02470	COG0436	Aminotransferase
C1H20_RS02485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1H20_RS02595	COG2816	NAD+ diphosphatase activity
C1H20_RS02600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C1H20_RS02630	COG2814	Major facilitator Superfamily
C1H20_RS02640	COG1289	transmembrane transporter activity
C1H20_RS02645	COG0151	Belongs to the GarS family
C1H20_RS02660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1H20_RS02665	COG2267	carboxylic ester hydrolase activity
C1H20_RS02670	COG0671	phosphoesterase, PA-phosphatase related
C1H20_RS02670	COG2453	phosphatase
C1H20_RS02695	COG4589	Belongs to the CDS family
C1H20_RS02710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C1H20_RS02745	COG0439	Biotin carboxylase
C1H20_RS02755	COG0511	ligase activity, forming carbon-carbon bonds
C1H20_RS02770	COG1324	tolerance protein
C1H20_RS02775	COG2356	endonuclease I
C1H20_RS02790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1H20_RS02800	COG1196	nuclear chromosome segregation
C1H20_RS02850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1H20_RS02875	COG3386	PFAM SMP-30 Gluconolaconase
C1H20_RS02890	COG3712	iron ion homeostasis
C1H20_RS02930	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1H20_RS02955	COG2353	YceI-like domain
C1H20_RS03010	COG1802	Transcriptional regulator
C1H20_RS03085	COG3039	Transposase
C1H20_RS03150	COG0435	Glutathione S-transferase
C1H20_RS03210	COG2409	Drug exporters of the RND superfamily
C1H20_RS03215	COG1506	peptidase
C1H20_RS03215	COG0823	Involved in the tonB-independent uptake of proteins
C1H20_RS03230	COG1959	2 iron, 2 sulfur cluster binding
C1H20_RS03270	COG0697	spore germination
C1H20_RS03285	COG4305	rare lipoprotein A
C1H20_RS03290	COG5297	Belongs to the glycosyl hydrolase family 6
C1H20_RS03300	COG1113	amino acid transport
C1H20_RS03360	COG3447	MASE1 domain protein
C1H20_RS03360	COG5002	protein histidine kinase activity
C1H20_RS03360	COG5001	Diguanylate cyclase
C1H20_RS03365	COG0840	transmembrane signaling receptor activity
C1H20_RS03375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C1H20_RS03375	COG5297	Belongs to the glycosyl hydrolase family 6
C1H20_RS03380	COG0659	secondary active sulfate transmembrane transporter activity
C1H20_RS03385	COG3706	GGDEF domain
C1H20_RS03400	COG0471	metal ion transport
C1H20_RS03400	COG3273	potassium ion transport
C1H20_RS03420	COG3275	phosphorelay sensor kinase activity
C1H20_RS03460	COG1505	serine-type exopeptidase activity
C1H20_RS03475	COG0436	Aminotransferase
C1H20_RS03495	COG2832	Protein of unknown function (DUF454)
C1H20_RS03565	COG2226	methyltransferase
C1H20_RS03570	COG5001	Diguanylate cyclase
C1H20_RS03570	COG3300	MHYT domain
C1H20_RS03575	COG0308	aminopeptidase N
C1H20_RS03610	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1H20_RS03625	COG3284	Transcriptional regulator
C1H20_RS03630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1H20_RS03635	COG1077	Cell shape determining protein MreB Mrl
C1H20_RS03645	COG1792	Involved in formation and maintenance of cell shape
C1H20_RS03660	COG0772	Belongs to the SEDS family
C1H20_RS03710	COG2951	lytic endotransglycosylase activity
C1H20_RS03715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1H20_RS03720	COG1686	Belongs to the peptidase S11 family
C1H20_RS03765	COG1056	cytidyltransferase-related domain
C1H20_RS03765	COG1051	belongs to the nudix hydrolase family
C1H20_RS03800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C1H20_RS03805	COG0673	inositol 2-dehydrogenase activity
C1H20_RS03810	COG2823	Periplasmic or secreted lipoprotein
C1H20_RS03815	COG4251	negative regulation of phosphorylation
C1H20_RS03820	COG0784	Response regulator, receiver
C1H20_RS03825	COG4191	Histidine kinase
C1H20_RS03830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1H20_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS03880	COG1459	type II secretion system
C1H20_RS03895	COG2165	general secretion pathway protein
C1H20_RS03900	COG4795	General secretion pathway protein
C1H20_RS03925	COG2188	Transcriptional regulator
C1H20_RS03935	COG1609	Transcriptional regulator
C1H20_RS03940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1H20_RS03945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1H20_RS03990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1H20_RS04000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1H20_RS04025	COG2205	protein histidine kinase activity
C1H20_RS04050	COG0583	DNA-binding transcription factor activity
C1H20_RS04070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C1H20_RS04080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1H20_RS04090	COG0697	spore germination
C1H20_RS04100	COG1307	EDD domain protein, DegV family
C1H20_RS04140	COG0402	S-adenosylhomocysteine deaminase activity
C1H20_RS04160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1H20_RS04180	COG0436	Aminotransferase
C1H20_RS04215	COG2211	Major facilitator Superfamily
C1H20_RS04220	COG1609	Transcriptional regulator
C1H20_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS04230	COG2851	Citrate transporter
C1H20_RS04250	COG0642	Histidine kinase
C1H20_RS04260	COG2197	response regulator
C1H20_RS04315	COG1560	Kdo2-lipid A biosynthetic process
C1H20_RS04320	COG1519	Transferase
C1H20_RS04325	COG1538	Outer membrane efflux protein
C1H20_RS04330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C1H20_RS04350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1H20_RS04360	COG2226	methyltransferase
C1H20_RS04400	COG0405	Gamma-glutamyltransferase
C1H20_RS04405	COG0840	transmembrane signaling receptor activity
C1H20_RS04410	COG0823	Involved in the tonB-independent uptake of proteins
C1H20_RS04410	COG1506	peptidase
C1H20_RS04410	COG4946	Tricorn protease homolog
C1H20_RS04445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1H20_RS04455	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C1H20_RS04485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1H20_RS04495	COG3781	membrane
C1H20_RS04500	COG0671	phosphoesterase, PA-phosphatase related
C1H20_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS04520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1H20_RS04525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1H20_RS04555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1H20_RS04595	COG1773	rubredoxin
C1H20_RS04600	COG2912	Transglutaminase-like superfamily
C1H20_RS04620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1H20_RS04645	COG0006	proline dipeptidase activity
C1H20_RS04670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1H20_RS04680	COG0346	lactoylglutathione lyase activity
C1H20_RS04690	COG1561	YicC-like family, N-terminal region
C1H20_RS04705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1H20_RS04715	COG0583	DNA-binding transcription factor activity
C1H20_RS04730	COG2271	Major facilitator Superfamily
C1H20_RS04745	COG2721	sulfolactate sulfo-lyase activity
C1H20_RS04755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1H20_RS04780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1H20_RS04810	COG0714	Associated with various cellular activities
C1H20_RS04830	COG2304	oxidoreductase activity
C1H20_RS04840	COG1301	dicarboxylic acid transport
C1H20_RS04845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1H20_RS04850	COG0596	Alpha beta hydrolase
C1H20_RS04860	COG0739	heme binding
C1H20_RS04865	COG1376	ErfK ybiS ycfS ynhG family protein
C1H20_RS04895	COG4149	molybdate abc transporter
C1H20_RS04900	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1H20_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1H20_RS04905	COG3453	Protein conserved in bacteria
C1H20_RS04920	COG3047	cAMP biosynthetic process
C1H20_RS04935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1H20_RS04965	COG0469	pyruvate kinase activity
C1H20_RS04970	COG3588	fructose-bisphosphate aldolase
C1H20_RS04975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C1H20_RS05010	COG0784	Response regulator, receiver
C1H20_RS05010	COG2198	Histidine kinase
C1H20_RS05010	COG2205	protein histidine kinase activity
C1H20_RS05040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1H20_RS05050	COG2895	sulfate adenylyltransferase (ATP) activity
C1H20_RS05050	COG0529	Catalyzes the synthesis of activated sulfate
C1H20_RS05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1H20_RS05060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1H20_RS05065	COG0308	aminopeptidase N
C1H20_RS05075	COG1115	amino acid carrier protein
C1H20_RS05080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1H20_RS05085	COG2272	Belongs to the type-B carboxylesterase lipase family
C1H20_RS05090	COG4948	Mandelate Racemase Muconate Lactonizing
C1H20_RS05095	COG3250	beta-galactosidase activity
C1H20_RS05105	COG5297	Belongs to the glycosyl hydrolase family 6
C1H20_RS05110	COG1609	Transcriptional regulator
C1H20_RS05145	COG3273	potassium ion transport
C1H20_RS05145	COG0471	metal ion transport
C1H20_RS05285	COG2003	Belongs to the UPF0758 family
C1H20_RS05305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C1H20_RS05400	COG0745	RESPONSE REGULATOR receiver
C1H20_RS05435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C1H20_RS05450	COG2194	sulfuric ester hydrolase activity
C1H20_RS05500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C1H20_RS05500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1H20_RS05510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1H20_RS05515	COG0564	pseudouridine synthase activity
C1H20_RS05535	COG0840	transmembrane signaling receptor activity
C1H20_RS05555	COG3387	PFAM Glycoside hydrolase 15-related
C1H20_RS05560	COG1877	trehalose-phosphatase activity
C1H20_RS05605	COG1116	anion transmembrane transporter activity
C1H20_RS05610	COG0542	response to heat
C1H20_RS05625	COG4206	TonB-dependent receptor
C1H20_RS05645	COG1797	cobyrinic acid a,c-diamide synthase activity
C1H20_RS05650	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C1H20_RS05680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1H20_RS05690	COG0019	diaminopimelate decarboxylase activity
C1H20_RS05695	COG4264	IucA IucC family
C1H20_RS05700	COG2814	Major facilitator Superfamily
C1H20_RS05705	COG4264	IucA IucC family
C1H20_RS05715	COG4772	TonB-dependent receptor
C1H20_RS05725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1H20_RS05725	COG4651	solute:proton antiporter activity
C1H20_RS05755	COG0488	(ABC) transporter
C1H20_RS05775	COG0657	acetylesterase activity
C1H20_RS05775	COG2755	lipolytic protein G-D-S-L family
C1H20_RS05795	COG0477	Major facilitator Superfamily
C1H20_RS05865	COG0824	Thioesterase
C1H20_RS05875	COG0848	biopolymer transport protein
C1H20_RS05890	COG2885	chlorophyll binding
C1H20_RS05900	COG0602	queuosine metabolic process
C1H20_RS05955	COG0583	DNA-binding transcription factor activity
C1H20_RS05980	COG1187	pseudouridine synthase activity
C1H20_RS06000	COG0514	ATP-dependent DNA helicase (RecQ)
C1H20_RS06005	COG0783	Belongs to the Dps family
C1H20_RS06010	COG1643	Atp-dependent helicase
C1H20_RS06060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1H20_RS06070	COG1215	transferase activity, transferring glycosyl groups
C1H20_RS06075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1H20_RS06085	COG1199	ATP-dependent helicase activity
C1H20_RS06105	COG1397	ADP-ribosylglycohydrolase
C1H20_RS06115	COG0189	ligase activity
C1H20_RS06130	COG0835	chemotaxis
C1H20_RS06135	COG0840	transmembrane signaling receptor activity
C1H20_RS06140	COG2198	Histidine kinase
C1H20_RS06140	COG0643	Histidine kinase
C1H20_RS06140	COG0784	Response regulator, receiver
C1H20_RS06165	COG1595	DNA-templated transcription, initiation
C1H20_RS06170	COG2304	oxidoreductase activity
C1H20_RS06175	COG1446	asparaginase
C1H20_RS06220	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1H20_RS06230	COG3645	SOS response
C1H20_RS06280	COG3537	Alpha-1,2-mannosidase
C1H20_RS06290	COG1472	Belongs to the glycosyl hydrolase 3 family
C1H20_RS06305	COG1388	LysM domain
C1H20_RS06305	COG3858	chitin binding
C1H20_RS06320	COG0837	glucose binding
C1H20_RS06325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1H20_RS06335	COG0494	nUDIX hydrolase
C1H20_RS06340	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1H20_RS06345	COG3956	TIGRFAM MazG family protein
C1H20_RS06355	COG0330	HflC and HflK could
C1H20_RS06400	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS06410	COG1309	transcriptional regulator
C1H20_RS06425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C1H20_RS06440	COG0516	GMP reductase activity
C1H20_RS06440	COG0517	IMP dehydrogenase activity
C1H20_RS06445	COG2982	Protein involved in outer membrane biogenesis
C1H20_RS06450	COG1272	protein, Hemolysin III
C1H20_RS06465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1H20_RS06470	COG0626	cystathionine gamma-synthase activity
C1H20_RS06475	COG0460	homoserine dehydrogenase
C1H20_RS06475	COG0527	aspartate kinase activity
C1H20_RS06490	COG1760	l-serine dehydratase
C1H20_RS06510	COG2353	YceI-like domain
C1H20_RS06530	COG0477	Major facilitator Superfamily
C1H20_RS06575	COG1842	Phage shock protein A
C1H20_RS06600	COG0754	glutathionylspermidine amidase activity
C1H20_RS06605	COG2814	Major facilitator Superfamily
C1H20_RS06680	COG0531	amino acid
C1H20_RS06685	COG2197	response regulator
C1H20_RS06705	COG1113	amino acid transport
C1H20_RS06710	COG1271	oxidase subunit
C1H20_RS06715	COG1294	oxidase, subunit
C1H20_RS06725	COG2239	Acts as a magnesium transporter
C1H20_RS06730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1H20_RS06735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1H20_RS06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1H20_RS06770	COG1137	ATPase activity
C1H20_RS06785	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C1H20_RS06795	COG0271	Belongs to the BolA IbaG family
C1H20_RS06820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1H20_RS06840	COG0628	permease
C1H20_RS06850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C1H20_RS06865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1H20_RS06870	COG1555	photosystem II stabilization
C1H20_RS06915	COG4774	siderophore transport
C1H20_RS06930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1H20_RS06935	COG0719	Fe-S assembly protein
C1H20_RS06940	COG0396	ATPase activity
C1H20_RS06945	COG0719	Fe-S assembly protein
C1H20_RS06960	COG0693	protein deglycase activity
C1H20_RS06995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1H20_RS07025	COG0519	Catalyzes the synthesis of GMP from XMP
C1H20_RS07030	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C1H20_RS07050	COG1764	response to oxidative stress
C1H20_RS07060	COG0384	phenazine biosynthesis protein PhzF
C1H20_RS07065	COG0384	phenazine biosynthesis protein PhzF
C1H20_RS07070	COG0527	aspartate kinase activity
C1H20_RS07095	COG0142	geranyltranstransferase activity
C1H20_RS07100	COG0629	single-stranded DNA binding
C1H20_RS07110	COG3713	MltA-interacting MipA family protein
C1H20_RS07120	COG0745	RESPONSE REGULATOR receiver
C1H20_RS07125	COG4251	negative regulation of phosphorylation
C1H20_RS07130	COG3706	GGDEF domain
C1H20_RS07130	COG2203	Gaf domain
C1H20_RS07130	COG5001	Diguanylate cyclase
C1H20_RS07130	COG4251	negative regulation of phosphorylation
C1H20_RS07135	COG0604	alcohol dehydrogenase
C1H20_RS07140	COG2080	2 iron, 2 sulfur cluster binding
C1H20_RS07145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1H20_RS07150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1H20_RS07155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1H20_RS07160	COG0746	molybdenum cofactor guanylyltransferase activity
C1H20_RS07190	COG2879	small protein
C1H20_RS07195	COG1966	Carbon starvation protein
C1H20_RS07200	COG1741	Belongs to the pirin family
C1H20_RS07220	COG1741	Belongs to the pirin family
C1H20_RS07240	COG3590	peptidase
C1H20_RS07245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS07255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1H20_RS07260	COG2200	EAL domain
C1H20_RS07260	COG2199	diguanylate cyclase activity
C1H20_RS07260	COG2202	Pas domain
C1H20_RS07265	COG0835	chemotaxis
C1H20_RS07270	COG0840	transmembrane signaling receptor activity
C1H20_RS07275	COG2198	Histidine kinase
C1H20_RS07275	COG0643	Histidine kinase
C1H20_RS07285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1H20_RS07300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1H20_RS07305	COG0745	RESPONSE REGULATOR receiver
C1H20_RS07315	COG2205	protein histidine kinase activity
C1H20_RS07320	COG4452	Inner membrane protein CreD
C1H20_RS07355	COG0735	belongs to the Fur family
C1H20_RS07370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1H20_RS07380	COG1309	transcriptional regulator
C1H20_RS07385	COG0667	Aldo Keto reductase
C1H20_RS07400	COG2207	Transcriptional regulator
C1H20_RS07410	COG0583	DNA-binding transcription factor activity
C1H20_RS07415	COG2814	Major facilitator Superfamily
C1H20_RS07435	COG1404	Belongs to the peptidase S8 family
C1H20_RS07445	COG3383	formate dehydrogenase (NAD+) activity
C1H20_RS07455	COG1271	oxidase subunit
C1H20_RS07460	COG1294	oxidase, subunit
C1H20_RS07510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1H20_RS07565	COG5002	protein histidine kinase activity
C1H20_RS07565	COG5001	Diguanylate cyclase
C1H20_RS07570	COG1187	pseudouridine synthase activity
C1H20_RS07595	COG0475	glutathione-regulated potassium exporter activity
C1H20_RS07600	COG1132	(ABC) transporter
C1H20_RS07650	COG2155	Conserved Protein
C1H20_RS07660	COG3118	belongs to the thioredoxin family
C1H20_RS07685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1H20_RS07715	COG2968	Membrane
C1H20_RS07730	COG3164	Protein of unknown function
C1H20_RS07740	COG0312	modulator of DNA gyrase
C1H20_RS07750	COG0312	modulator of DNA gyrase
C1H20_RS07760	COG4104	PAAR repeat-containing protein
C1H20_RS07765	COG0142	geranyltranstransferase activity
C1H20_RS07780	COG1785	Belongs to the alkaline phosphatase family
C1H20_RS07785	COG1301	dicarboxylic acid transport
C1H20_RS07790	COG4106	trans-aconitate 2-methyltransferase activity
C1H20_RS07805	COG4191	Histidine kinase
C1H20_RS07840	COG0791	NLP P60 protein
C1H20_RS07845	COG0791	NLP P60 protein
C1H20_RS07850	COG1047	Peptidyl-prolyl cis-trans
C1H20_RS07855	COG2311	Membrane
C1H20_RS07860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1H20_RS07865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1H20_RS07885	COG3590	peptidase
C1H20_RS07890	COG3590	peptidase
C1H20_RS07910	COG0489	protein tyrosine kinase activity
C1H20_RS07940	COG0412	Dienelactone hydrolase
C1H20_RS07955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1H20_RS07990	COG0433	COG0433 Predicted ATPase
C1H20_RS08015	COG2890	protein-(glutamine-N5) methyltransferase activity
C1H20_RS08030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1H20_RS08035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1H20_RS08135	COG4221	oxidoreductase activity
C1H20_RS08155	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1H20_RS08175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C1H20_RS08180	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C1H20_RS08200	COG0839	Belongs to the complex I subunit 6 family
C1H20_RS08220	COG1007	ATP synthesis coupled electron transport
C1H20_RS08235	COG0195	Participates in both transcription termination and antitermination
C1H20_RS08295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1H20_RS08305	COG2095	MarC family integral membrane protein
C1H20_RS08320	COG1611	Belongs to the LOG family
C1H20_RS08325	COG3275	phosphorelay sensor kinase activity
C1H20_RS08385	COG3505	Type IV secretory pathway VirD4
C1H20_RS08405	COG2948	multi-organism process
C1H20_RS08425	COG3702	type iv secretory pathway
C1H20_RS08460	COG3501	Rhs element vgr protein
C1H20_RS08460	COG3409	Peptidoglycan-binding domain 1 protein
C1H20_RS08505	COG0366	Alpha amylase catalytic
C1H20_RS08520	COG1082	Xylose isomerase domain protein TIM barrel
C1H20_RS08550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1H20_RS08620	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS08630	COG2244	polysaccharide biosynthetic process
C1H20_RS08635	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS08660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1H20_RS08670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1H20_RS08700	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS08735	COG0322	excinuclease ABC activity
C1H20_RS08760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1H20_RS08770	COG0784	Response regulator, receiver
C1H20_RS08770	COG4191	Histidine kinase
C1H20_RS08790	COG0552	protein localization to endoplasmic reticulum
C1H20_RS08800	COG3938	Belongs to the proline racemase family
C1H20_RS08820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1H20_RS08830	COG0006	proline dipeptidase activity
C1H20_RS08850	COG0531	amino acid
C1H20_RS08880	COG4206	TonB-dependent receptor
C1H20_RS08890	COG3507	Belongs to the glycosyl hydrolase 43 family
C1H20_RS08895	COG1506	peptidase
C1H20_RS08895	COG0823	Involved in the tonB-independent uptake of proteins
C1H20_RS08905	COG4206	TonB-dependent receptor
C1H20_RS08920	COG3039	Transposase
C1H20_RS08930	COG2801	Transposase and inactivated derivatives
C1H20_RS08935	COG0326	Molecular chaperone. Has ATPase activity
C1H20_RS08940	COG0742	ribosomal rna small subunit methyltransferase
C1H20_RS08960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1H20_RS08965	COG0405	Gamma-glutamyltransferase
C1H20_RS08970	COG3291	Pkd domain containing protein
C1H20_RS09000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C1H20_RS09020	COG1862	Preprotein translocase
C1H20_RS09030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1H20_RS09050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1H20_RS09050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1H20_RS09055	COG1105	Belongs to the carbohydrate kinase PfkB family
C1H20_RS09060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1H20_RS09060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1H20_RS09065	COG1609	Transcriptional regulator
C1H20_RS09075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1H20_RS09085	COG2902	Dehydrogenase
C1H20_RS09090	COG1609	Transcriptional regulator
C1H20_RS09090	COG2207	Transcriptional regulator
C1H20_RS09095	COG1335	isochorismatase
C1H20_RS09100	COG0477	Major facilitator Superfamily
C1H20_RS09110	COG5002	protein histidine kinase activity
C1H20_RS09110	COG2205	protein histidine kinase activity
C1H20_RS09110	COG0784	Response regulator, receiver
C1H20_RS09115	COG2733	membrane
C1H20_RS09125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1H20_RS09130	COG2223	nitrite transmembrane transporter activity
C1H20_RS09140	COG0243	molybdopterin cofactor binding
C1H20_RS09150	COG0477	Major facilitator Superfamily
C1H20_RS09155	COG2703	oxygen carrier activity
C1H20_RS09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1H20_RS09170	COG0174	glutamine synthetase
C1H20_RS09175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C1H20_RS09210	COG3842	ATPase activity
C1H20_RS09220	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1H20_RS09225	COG1177	transmembrane transport
C1H20_RS09255	COG4535	Mg2 and Co2 transporter CorC
C1H20_RS09275	COG1702	phosphate starvation-inducible protein PhoH
C1H20_RS09295	COG0741	lytic transglycosylase activity
C1H20_RS09300	COG0723	plastoquinol--plastocyanin reductase activity
C1H20_RS09305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1H20_RS09310	COG2857	Cytochrome c1
C1H20_RS09315	COG0625	glutathione transferase activity
C1H20_RS09320	COG2969	positive regulation of protein catabolic process
C1H20_RS09335	COG1201	RNA secondary structure unwinding
C1H20_RS09345	COG0840	transmembrane signaling receptor activity
C1H20_RS09350	COG0835	chemotaxis
C1H20_RS09400	COG0582	viral genome integration into host DNA
C1H20_RS09430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1H20_RS09445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1H20_RS09450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1H20_RS09450	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1H20_RS09460	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1H20_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS09500	COG5001	Diguanylate cyclase
C1H20_RS09500	COG3300	MHYT domain
C1H20_RS09505	COG2081	HI0933 family
C1H20_RS09510	COG4681	YaeQ
C1H20_RS09545	COG0513	Belongs to the DEAD box helicase family
C1H20_RS09550	COG0488	(ABC) transporter
C1H20_RS09565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1H20_RS09570	COG0483	inositol monophosphate 1-phosphatase activity
C1H20_RS09585	COG5001	Diguanylate cyclase
C1H20_RS09585	COG3300	MHYT domain
C1H20_RS09590	COG1509	lysine 2,3-aminomutase activity
C1H20_RS09605	COG0402	S-adenosylhomocysteine deaminase activity
C1H20_RS09630	COG4677	pectinesterase activity
C1H20_RS09675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1H20_RS09710	COG2166	iron-sulfur cluster assembly
C1H20_RS09725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1H20_RS09735	COG0137	argininosuccinate synthase activity
C1H20_RS09740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1H20_RS09745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1H20_RS09810	COG1294	oxidase, subunit
C1H20_RS09820	COG4988	ABC transporter
C1H20_RS09825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1H20_RS09890	COG0436	Aminotransferase
C1H20_RS09910	COG1187	pseudouridine synthase activity
C1H20_RS09915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1H20_RS09920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1H20_RS09925	COG2350	Protein conserved in bacteria
C1H20_RS09950	COG2182	Extracellular solute-binding protein
C1H20_RS09960	COG0395	ABC-type sugar transport system, permease component
C1H20_RS09985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1H20_RS09990	COG2957	Belongs to the agmatine deiminase family
C1H20_RS10010	COG0539	negative regulation of cytoplasmic translation
C1H20_RS10025	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1H20_RS10040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1H20_RS10045	COG0475	glutathione-regulated potassium exporter activity
C1H20_RS10045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1H20_RS10085	COG2197	response regulator
C1H20_RS10100	COG1335	isochorismatase
C1H20_RS10115	COG2814	Major facilitator Superfamily
C1H20_RS10130	COG1914	H( )-stimulated, divalent metal cation uptake system
C1H20_RS10150	COG0668	transmembrane transport
C1H20_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS10180	COG1183	phosphatidylcholine synthase activity
C1H20_RS10190	COG3243	poly(R)-hydroxyalkanoic acid synthase
C1H20_RS10205	COG0723	plastoquinol--plastocyanin reductase activity
C1H20_RS10205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1H20_RS10215	COG2183	response to ionizing radiation
C1H20_RS10220	COG5001	Diguanylate cyclase
C1H20_RS10300	COG0800	Aldolase
C1H20_RS10305	COG0129	dihydroxy-acid dehydratase activity
C1H20_RS10310	COG0363	glucosamine-6-phosphate deaminase activity
C1H20_RS10320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1H20_RS10330	COG0354	folic acid binding
C1H20_RS10345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1H20_RS10350	COG1053	succinate dehydrogenase
C1H20_RS10360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1H20_RS10375	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1H20_RS10400	COG0811	peptide transport
C1H20_RS10405	COG0848	biopolymer transport protein
C1H20_RS10425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1H20_RS10440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1H20_RS10460	COG0582	viral genome integration into host DNA
C1H20_RS10525	COG0583	DNA-binding transcription factor activity
C1H20_RS10545	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C1H20_RS10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1H20_RS10595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1H20_RS10625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1H20_RS10625	COG0140	phosphoribosyl-ATP diphosphatase activity
C1H20_RS10665	COG0531	amino acid
C1H20_RS10670	COG0531	amino acid
C1H20_RS10685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1H20_RS10690	COG0277	FAD linked oxidase domain protein
C1H20_RS10725	COG1024	Enoyl-CoA hydratase
C1H20_RS10750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1H20_RS10755	COG2258	MOSC domain
C1H20_RS10765	COG0505	Belongs to the CarA family
C1H20_RS10775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1H20_RS10780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1H20_RS10790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1H20_RS10815	COG3279	Response regulator of the LytR AlgR family
C1H20_RS10835	COG2205	protein histidine kinase activity
C1H20_RS10835	COG0784	Response regulator, receiver
C1H20_RS10835	COG2198	Histidine kinase
C1H20_RS10840	COG0784	Response regulator, receiver
C1H20_RS10840	COG2198	Histidine kinase
C1H20_RS10840	COG2205	protein histidine kinase activity
C1H20_RS10845	COG1024	Enoyl-CoA hydratase
C1H20_RS10850	COG0318	PFAM AMP-dependent synthetase and ligase
C1H20_RS10880	COG2267	carboxylic ester hydrolase activity
C1H20_RS10905	COG0840	transmembrane signaling receptor activity
C1H20_RS10915	COG0835	chemotaxis
C1H20_RS10945	COG0840	transmembrane signaling receptor activity
C1H20_RS10950	COG0840	transmembrane signaling receptor activity
C1H20_RS10955	COG0840	transmembrane signaling receptor activity
C1H20_RS10960	COG0840	transmembrane signaling receptor activity
C1H20_RS10965	COG0840	transmembrane signaling receptor activity
C1H20_RS10980	COG0840	transmembrane signaling receptor activity
C1H20_RS10990	COG0745	RESPONSE REGULATOR receiver
C1H20_RS11000	COG0835	chemotaxis
C1H20_RS11005	COG1192	Involved in chromosome partitioning
C1H20_RS11010	COG1360	Flagellar Motor Protein
C1H20_RS11015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1H20_RS11115	COG0643	Histidine kinase
C1H20_RS11115	COG0784	Response regulator, receiver
C1H20_RS11115	COG2198	Histidine kinase
C1H20_RS11170	COG1684	flagellar biosynthetic protein fliR
C1H20_RS11175	COG1987	bacterial-type flagellum assembly
C1H20_RS11240	COG1677	Flagellar hook-basal body complex protein FliE
C1H20_RS11245	COG1216	Glycosyl transferase, family 2
C1H20_RS11245	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS11275	COG2201	protein-glutamate methylesterase activity
C1H20_RS11305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1H20_RS11310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1H20_RS11315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1H20_RS11325	COG3951	Flagellar rod assembly protein muramidase FlgJ
C1H20_RS11325	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1H20_RS11350	COG4787	bacterial-type flagellum-dependent cell motility
C1H20_RS11360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1H20_RS11365	COG1558	bacterial-type flagellum-dependent cell motility
C1H20_RS11375	COG0784	Response regulator, receiver
C1H20_RS11375	COG0835	chemotaxis
C1H20_RS11395	COG4191	Histidine kinase
C1H20_RS11430	COG2915	High frequency lysogenization protein hflD homolog
C1H20_RS11450	COG0542	response to heat
C1H20_RS11470	COG0492	ferredoxin-NADP+ reductase activity
C1H20_RS11475	COG1674	ftsk spoiiie
C1H20_RS11495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1H20_RS11500	COG0038	chloride channel
C1H20_RS11505	COG0183	Belongs to the thiolase family
C1H20_RS11510	COG1024	Enoyl-CoA hydratase
C1H20_RS11510	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1H20_RS11535	COG1426	Protein conserved in bacteria
C1H20_RS11545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1H20_RS11560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1H20_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS11580	COG2124	cytochrome p450
C1H20_RS11605	COG0708	Exodeoxyribonuclease III
C1H20_RS11615	COG0303	'Molybdopterin
C1H20_RS11620	COG0746	molybdenum cofactor guanylyltransferase activity
C1H20_RS11630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1H20_RS11630	COG1648	precorrin-2 dehydrogenase activity
C1H20_RS11640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1H20_RS11645	COG2223	nitrite transmembrane transporter activity
C1H20_RS11650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1H20_RS11680	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C1H20_RS11690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C1H20_RS11700	COG0579	oxidoreductase
C1H20_RS11715	COG3685	Protein conserved in bacteria
C1H20_RS11720	COG2201	protein-glutamate methylesterase activity
C1H20_RS11730	COG5001	Diguanylate cyclase
C1H20_RS11800	COG3590	peptidase
C1H20_RS11815	COG1999	signal sequence binding
C1H20_RS11830	COG1733	regulation of RNA biosynthetic process
C1H20_RS11860	COG1238	metal cluster binding
C1H20_RS11870	COG0840	transmembrane signaling receptor activity
C1H20_RS11905	COG0840	transmembrane signaling receptor activity
C1H20_RS11910	COG4191	Histidine kinase
C1H20_RS11910	COG0784	Response regulator, receiver
C1H20_RS11970	COG0840	transmembrane signaling receptor activity
C1H20_RS12075	COG0428	transporter
C1H20_RS12085	COG1530	ribonuclease E activity
C1H20_RS12120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C1H20_RS12150	COG5599	Phosphatase
C1H20_RS12165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1H20_RS12170	COG1061	Type III restriction enzyme res subunit
C1H20_RS12225	COG0629	single-stranded DNA binding
C1H20_RS12230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1H20_RS12250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1H20_RS12350	COG3039	Transposase
C1H20_RS12450	COG2003	Belongs to the UPF0758 family
C1H20_RS12540	COG1012	belongs to the aldehyde dehydrogenase family
C1H20_RS12565	COG0697	spore germination
C1H20_RS12570	COG1794	racemase activity, acting on amino acids and derivatives
C1H20_RS12580	COG0671	phosphoesterase, PA-phosphatase related
C1H20_RS12595	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C1H20_RS12600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C1H20_RS12605	COG2203	Gaf domain
C1H20_RS12605	COG3706	GGDEF domain
C1H20_RS12605	COG5001	Diguanylate cyclase
C1H20_RS12605	COG4251	negative regulation of phosphorylation
C1H20_RS12615	COG1472	Belongs to the glycosyl hydrolase 3 family
C1H20_RS12670	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1H20_RS12690	COG0477	Major facilitator Superfamily
C1H20_RS12700	COG1070	Carbohydrate kinase
C1H20_RS12710	COG1501	Belongs to the glycosyl hydrolase 31 family
C1H20_RS12750	COG0800	Aldolase
C1H20_RS12765	COG3734	2-keto-3-deoxy-galactonokinase
C1H20_RS12770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1H20_RS12780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1H20_RS12795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1H20_RS12800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1H20_RS12810	COG0351	phosphomethylpyrimidine kinase
C1H20_RS12810	COG0352	thiamine-phosphate diphosphorylase activity
C1H20_RS12835	COG0583	DNA-binding transcription factor activity
C1H20_RS12840	COG1741	Belongs to the pirin family
C1H20_RS12875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1H20_RS12890	COG4771	TonB-dependent receptor
C1H20_RS12900	COG1546	Belongs to the CinA family
C1H20_RS12905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1H20_RS12920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1H20_RS12925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1H20_RS12935	COG1534	Rna-binding protein
C1H20_RS12950	COG1238	metal cluster binding
C1H20_RS12965	COG2840	Smr protein MutS2
C1H20_RS13025	COG2134	cdp-diacylglycerol pyrophosphatase
C1H20_RS13055	COG1253	flavin adenine dinucleotide binding
C1H20_RS13070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1H20_RS13075	COG0477	Major facilitator Superfamily
C1H20_RS13080	COG1132	(ABC) transporter
C1H20_RS13100	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS13105	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS13110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1H20_RS13140	COG2244	polysaccharide biosynthetic process
C1H20_RS13155	COG3038	cytochrome b561
C1H20_RS13190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1H20_RS13210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1H20_RS13225	COG4191	Histidine kinase
C1H20_RS13225	COG0784	Response regulator, receiver
C1H20_RS13230	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C1H20_RS13280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1H20_RS13375	COG3039	Transposase
C1H20_RS13455	COG2003	Belongs to the UPF0758 family
C1H20_RS13490	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C1H20_RS13535	COG0583	DNA-binding transcription factor activity
C1H20_RS13550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1H20_RS13560	COG0077	Prephenate dehydratase
C1H20_RS13560	COG1605	Chorismate mutase
C1H20_RS13570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1H20_RS13625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1H20_RS13635	COG4993	Dehydrogenase
C1H20_RS13655	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C1H20_RS13665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1H20_RS13700	COG0316	Belongs to the HesB IscA family
C1H20_RS13730	COG0288	reversible hydration of carbon dioxide
C1H20_RS13755	COG2925	Exonuclease
C1H20_RS13770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C1H20_RS13790	COG0488	(ABC) transporter
C1H20_RS13795	COG2264	protein methyltransferase activity
C1H20_RS13830	COG0494	nUDIX hydrolase
C1H20_RS13840	COG1024	Enoyl-CoA hydratase
C1H20_RS13850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1H20_RS13855	COG0659	secondary active sulfate transmembrane transporter activity
C1H20_RS13880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1H20_RS13885	COG0573	inorganic phosphate transmembrane transporter activity
C1H20_RS13890	COG0581	inorganic phosphate transmembrane transporter activity
C1H20_RS13900	COG0704	Plays a role in the regulation of phosphate uptake
C1H20_RS13920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1H20_RS13935	COG0557	exoribonuclease II activity
C1H20_RS13955	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13960	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13965	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13970	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13975	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13980	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13985	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS13995	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS14000	COG2226	methyltransferase
C1H20_RS14005	COG0646	methionine synthase
C1H20_RS14005	COG1410	methionine synthase
C1H20_RS14010	COG0646	methionine synthase
C1H20_RS14010	COG1410	methionine synthase
C1H20_RS14030	COG1609	Transcriptional regulator
C1H20_RS14060	COG0386	Belongs to the glutathione peroxidase family
C1H20_RS14070	COG1725	Transcriptional regulator
C1H20_RS14075	COG1131	(ABC) transporter
C1H20_RS14105	COG1253	flavin adenine dinucleotide binding
C1H20_RS14120	COG2850	peptidyl-arginine hydroxylation
C1H20_RS14155	COG1132	(ABC) transporter
C1H20_RS14160	COG0583	DNA-binding transcription factor activity
C1H20_RS14165	COG2274	protein secretion by the type I secretion system
C1H20_RS14190	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1H20_RS14210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1H20_RS14215	COG1420	regulation of RNA biosynthetic process
C1H20_RS14220	COG0497	DNA recombination
C1H20_RS14230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1H20_RS14250	COG1404	Belongs to the peptidase S8 family
C1H20_RS14350	COG3039	Transposase
C1H20_RS14405	COG3706	GGDEF domain
C1H20_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS14435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1H20_RS14450	COG0583	DNA-binding transcription factor activity
C1H20_RS14465	COG0415	Belongs to the DNA photolyase family
C1H20_RS14470	COG0305	Participates in initiation and elongation during chromosome replication
C1H20_RS14480	COG0367	asparagine synthase
C1H20_RS14495	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS14510	COG0084	hydrolase, TatD family'
C1H20_RS14515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1H20_RS14575	COG0386	Belongs to the glutathione peroxidase family
C1H20_RS14580	COG0339	signal peptide processing
C1H20_RS14615	COG3104	oligopeptide transport
C1H20_RS14645	COG2814	Major facilitator Superfamily
C1H20_RS14650	COG1566	PFAM secretion protein HlyD family protein
C1H20_RS14695	COG4774	siderophore transport
C1H20_RS14705	COG0367	asparagine synthase
C1H20_RS14720	COG1393	Belongs to the ArsC family
C1H20_RS14790	COG0528	UMP kinase activity
C1H20_RS14800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1H20_RS14805	COG0575	Belongs to the CDS family
C1H20_RS14815	COG0750	zinc metalloprotease
C1H20_RS14870	COG1981	membrane
C1H20_RS14895	COG1695	Transcriptional regulator
C1H20_RS14925	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1H20_RS14935	COG2040	homocysteine
C1H20_RS14940	COG0833	amino acid
C1H20_RS14950	COG0346	lactoylglutathione lyase activity
C1H20_RS14975	COG2878	Part of a membrane complex involved in electron transport
C1H20_RS14990	COG1595	DNA-templated transcription, initiation
C1H20_RS15015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1H20_RS15030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1H20_RS15035	COG0251	oxidation-reduction process
C1H20_RS15045	COG3039	Transposase
C1H20_RS15055	COG0392	lysyltransferase activity
C1H20_RS15055	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1H20_RS15095	COG2814	Major facilitator Superfamily
C1H20_RS15100	COG1902	pentaerythritol trinitrate reductase activity
C1H20_RS15125	COG2824	Alkylphosphonate utilization operon protein PhnA
C1H20_RS15135	COG1047	Peptidyl-prolyl cis-trans
C1H20_RS15180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1H20_RS15190	COG5487	UPF0391 membrane protein
C1H20_RS15195	COG1451	nucleotide metabolic process
C1H20_RS15215	COG0183	Belongs to the thiolase family
C1H20_RS15250	COG1793	dna ligase
C1H20_RS15250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C1H20_RS15260	COG1793	dna ligase
C1H20_RS15265	COG1201	RNA secondary structure unwinding
C1H20_RS15275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1H20_RS15280	COG1278	Cold shock
C1H20_RS15285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C1H20_RS15290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C1H20_RS15300	COG3046	protein related to deoxyribodipyrimidine photolyase
C1H20_RS15305	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C1H20_RS15305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1H20_RS15310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1H20_RS15315	COG2954	triphosphatase activity
C1H20_RS15365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1H20_RS15400	COG1024	Enoyl-CoA hydratase
C1H20_RS15405	COG1960	acyl-CoA dehydrogenase activity
C1H20_RS15415	COG3800	Transcriptional regulator
C1H20_RS15415	COG1396	sequence-specific DNA binding
C1H20_RS15425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C1H20_RS15430	COG3250	beta-galactosidase activity
C1H20_RS15555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1H20_RS15610	COG5297	Belongs to the glycosyl hydrolase family 6
C1H20_RS15630	COG1309	transcriptional regulator
C1H20_RS15635	COG0436	Aminotransferase
C1H20_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS15645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1H20_RS15660	COG3483	tryptophan 2,3-dioxygenase activity
C1H20_RS15735	COG2003	Belongs to the UPF0758 family
C1H20_RS15780	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C1H20_RS15785	COG0631	protein serine/threonine phosphatase activity
C1H20_RS15790	COG4245	von Willebrand factor, type A
C1H20_RS15840	COG0534	Mate efflux family protein
C1H20_RS15870	COG2070	2-Nitropropane dioxygenase
C1H20_RS15885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1H20_RS15890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1H20_RS15900	COG3534	alpha-L-arabinofuranosidase
C1H20_RS15930	COG0784	Response regulator, receiver
C1H20_RS15930	COG4191	Histidine kinase
C1H20_RS15935	COG2205	protein histidine kinase activity
C1H20_RS15935	COG4999	Histidine kinase
C1H20_RS15935	COG3850	Histidine kinase
C1H20_RS15935	COG3437	response regulator, receiver
C1H20_RS15940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1H20_RS15950	COG2205	protein histidine kinase activity
C1H20_RS15955	COG5507	3-demethylubiquinone-9 3-methyltransferase
C1H20_RS15965	COG4771	TonB-dependent receptor
C1H20_RS15990	COG2172	sigma factor antagonist activity
C1H20_RS15995	COG1366	Belongs to the anti-sigma-factor antagonist family
C1H20_RS16000	COG1366	Belongs to the anti-sigma-factor antagonist family
C1H20_RS16010	COG1902	pentaerythritol trinitrate reductase activity
C1H20_RS16020	COG0326	Molecular chaperone. Has ATPase activity
C1H20_RS16025	COG2207	Transcriptional regulator
C1H20_RS16040	COG3152	Membrane
C1H20_RS16055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1H20_RS16060	COG1845	cytochrome c oxidase, subunit III
C1H20_RS16065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1H20_RS16095	COG0196	riboflavin kinase activity
C1H20_RS16125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1H20_RS16130	COG0824	Thioesterase
C1H20_RS16140	COG1946	Acyl-CoA thioesterase
C1H20_RS16150	COG1595	DNA-templated transcription, initiation
C1H20_RS16210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1H20_RS16235	COG2197	response regulator
C1H20_RS16240	COG4585	Histidine kinase
C1H20_RS16255	COG2894	cell division
C1H20_RS16270	COG5002	protein histidine kinase activity
C1H20_RS16275	COG0745	RESPONSE REGULATOR receiver
C1H20_RS16310	COG2814	Major facilitator Superfamily
C1H20_RS16340	COG0656	L-ascorbic acid biosynthetic process
C1H20_RS16345	COG0753	catalase activity
C1H20_RS16360	COG1917	Cupin 2, conserved barrel domain protein
C1H20_RS16360	COG2207	Transcriptional regulator
C1H20_RS16380	COG1506	peptidase
C1H20_RS16380	COG0823	Involved in the tonB-independent uptake of proteins
C1H20_RS16390	COG1297	OPT oligopeptide transporter protein
C1H20_RS16415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1H20_RS16440	COG2080	2 iron, 2 sulfur cluster binding
C1H20_RS16445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1H20_RS16450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1H20_RS16495	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS16500	COG3537	Alpha-1,2-mannosidase
C1H20_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS16515	COG3387	PFAM Glycoside hydrolase 15-related
C1H20_RS16525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1H20_RS16575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1H20_RS16640	COG0308	aminopeptidase N
C1H20_RS16655	COG0330	HflC and HflK could
C1H20_RS16660	COG0330	HflC and HflK could
C1H20_RS16680	COG0678	peroxiredoxin activity
C1H20_RS16690	COG4953	penicillin-binding protein 1C
C1H20_RS16715	COG2373	Large extracellular alpha-helical protein
C1H20_RS16745	COG3609	addiction module antidote protein, CC2985 family
C1H20_RS16770	COG3829	transcription factor binding
C1H20_RS16865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1H20_RS16870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1H20_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS16890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1H20_RS16895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1H20_RS16905	COG1399	metal-binding, possibly nucleic acid-binding protein
C1H20_RS16935	COG0714	Associated with various cellular activities
C1H20_RS16955	COG0537	adenosine 5'-monophosphoramidase activity
C1H20_RS16985	COG0314	molybdopterin synthase activity
C1H20_RS16990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1H20_RS17010	COG1234	tRNA 3'-trailer cleavage
C1H20_RS17020	COG0859	PFAM glycosyl transferase family 9
C1H20_RS17035	COG0631	protein serine/threonine phosphatase activity
C1H20_RS17040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1H20_RS17070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1H20_RS17145	COG0473	3-isopropylmalate dehydrogenase activity
C1H20_RS17160	COG4783	chaperone-mediated protein folding
C1H20_RS17165	COG0745	RESPONSE REGULATOR receiver
C1H20_RS17175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1H20_RS17185	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS17190	COG0671	phosphoesterase, PA-phosphatase related
C1H20_RS17205	COG3291	Pkd domain containing protein
C1H20_RS17210	COG2833	Protein of unknown function (DUF455)
C1H20_RS17230	COG0285	dihydrofolate synthase activity
C1H20_RS17245	COG0406	alpha-ribazole phosphatase activity
C1H20_RS17270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C1H20_RS17275	COG4208	sulfate ABC transporter
C1H20_RS17280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C1H20_RS17285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C1H20_RS17320	COG1902	pentaerythritol trinitrate reductase activity
C1H20_RS17320	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1H20_RS17345	COG0625	glutathione transferase activity
C1H20_RS17355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1H20_RS17360	COG1217	gtp-binding protein TYPA
C1H20_RS17370	COG0154	amidase activity
C1H20_RS17385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C1H20_RS17420	COG0201	protein transport
C1H20_RS17580	COG0250	Participates in transcription elongation, termination and antitermination
C1H20_RS17615	COG0012	GTP binding
C1H20_RS17620	COG0193	aminoacyl-tRNA hydrolase activity
C1H20_RS17630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1H20_RS17680	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1H20_RS17700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1H20_RS17730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1H20_RS17735	COG1404	Belongs to the peptidase S8 family
C1H20_RS17740	COG1404	Belongs to the peptidase S8 family
C1H20_RS17745	COG1404	Belongs to the peptidase S8 family
C1H20_RS17750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1H20_RS17815	COG0778	Nitroreductase
C1H20_RS17820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1H20_RS17820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1H20_RS17840	COG2890	protein-(glutamine-N5) methyltransferase activity
C1H20_RS17850	COG3634	alkyl hydroperoxide reductase activity
C1H20_RS17855	COG0583	DNA-binding transcription factor activity
C1H20_RS17860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1H20_RS17885	COG2197	response regulator
C1H20_RS17890	COG5002	protein histidine kinase activity
C1H20_RS17890	COG2205	protein histidine kinase activity
C1H20_RS17890	COG0784	Response regulator, receiver
C1H20_RS17920	COG0697	spore germination
C1H20_RS17950	COG3386	PFAM SMP-30 Gluconolaconase
C1H20_RS17970	COG1024	Enoyl-CoA hydratase
C1H20_RS17980	COG0318	PFAM AMP-dependent synthetase and ligase
C1H20_RS17985	COG0583	DNA-binding transcription factor activity
C1H20_RS17990	COG3384	dioxygenase
C1H20_RS18020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1H20_RS18025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1H20_RS18035	COG2096	Adenosyltransferase
C1H20_RS18040	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1H20_RS18070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C1H20_RS18105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1H20_RS18115	COG0642	Histidine kinase
C1H20_RS18130	COG4181	ATPase activity
C1H20_RS18140	COG2175	clavaminate synthase activity
C1H20_RS18150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C1H20_RS18175	COG4771	TonB-dependent receptor
C1H20_RS18190	COG0667	Aldo Keto reductase
C1H20_RS18195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1H20_RS18210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1H20_RS18315	COG0366	Alpha amylase catalytic
C1H20_RS18355	COG3321	synthase
C1H20_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS18355	COG0604	alcohol dehydrogenase
C1H20_RS18370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1H20_RS18385	COG0494	nUDIX hydrolase
C1H20_RS18400	COG0739	heme binding
C1H20_RS18425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1H20_RS18430	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1H20_RS18455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1H20_RS18470	COG3116	cell division
C1H20_RS18520	COG1988	membrane-bound metal-dependent
C1H20_RS18525	COG0277	FAD linked oxidase domain protein
C1H20_RS18535	COG0745	RESPONSE REGULATOR receiver
C1H20_RS18540	COG2205	protein histidine kinase activity
C1H20_RS18550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C1H20_RS18555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C1H20_RS18580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1H20_RS18610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1H20_RS18610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1H20_RS18635	COG0488	(ABC) transporter
C1H20_RS18640	COG0242	peptide deformylase activity
C1H20_RS18645	COG1393	Belongs to the ArsC family
C1H20_RS18660	COG0457	Tetratricopeptide repeat
C1H20_RS18720	COG2188	Transcriptional regulator
C1H20_RS18730	COG1450	Type ii and iii secretion system protein
C1H20_RS18745	COG3166	PFAM Fimbrial assembly family protein
C1H20_RS18750	COG3156	type II secretion system protein K
C1H20_RS18755	COG4795	General secretion pathway protein
C1H20_RS18760	COG2165	general secretion pathway protein
C1H20_RS18765	COG4970	Tfp pilus assembly protein FimT
C1H20_RS18770	COG2165	general secretion pathway protein
C1H20_RS18775	COG1459	type II secretion system
C1H20_RS18780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1H20_RS18785	COG1404	Belongs to the peptidase S8 family
C1H20_RS18800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1H20_RS18800	COG0047	phosphoribosylformylglycinamidine synthase activity
C1H20_RS18805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1H20_RS18810	COG4974	Belongs to the 'phage' integrase family
C1H20_RS18825	COG0795	lipopolysaccharide-transporting ATPase activity
C1H20_RS18890	COG1183	phosphatidylcholine synthase activity
C1H20_RS18915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1H20_RS18920	COG1127	ABC transporter
C1H20_RS18925	COG3218	ABC-type transport auxiliary lipoprotein component
C1H20_RS18925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1H20_RS19000	COG2086	electron transfer activity
C1H20_RS19010	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C1H20_RS19010	COG0662	Cupin 2, conserved barrel domain protein
C1H20_RS19015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1H20_RS19020	COG0463	Glycosyl transferase, family 2
C1H20_RS19040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1H20_RS19045	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C1H20_RS19060	COG0438	transferase activity, transferring glycosyl groups
C1H20_RS19085	COG0626	cystathionine gamma-synthase activity
C1H20_RS19120	COG0625	glutathione transferase activity
C1H20_RS19135	COG0513	Belongs to the DEAD box helicase family
C1H20_RS19140	COG0720	synthase
C1H20_RS19155	COG1956	GAF domain-containing protein
C1H20_RS19185	COG0339	signal peptide processing
C1H20_RS19190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1H20_RS19245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1H20_RS19255	COG1136	(ABC) transporter
C1H20_RS19265	COG0577	efflux transmembrane transporter activity
C1H20_RS19265	COG1136	(ABC) transporter
C1H20_RS19280	COG4191	Histidine kinase
C1H20_RS19345	COG0356	it plays a direct role in the translocation of protons across the membrane
C1H20_RS19360	COG1228	amidohydrolase
C1H20_RS19365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1H20_RS19375	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1H20_RS19415	COG2011	ABC-type metal ion transport system permease component
C1H20_RS19425	COG0697	spore germination
C1H20_RS19455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1H20_RS19460	COG1187	pseudouridine synthase activity
C1H20_RS19465	COG2813	Specifically methylates the guanine in position
C1H20_RS19485	COG5002	protein histidine kinase activity
C1H20_RS19565	COG0842	Transport permease protein
C1H20_RS19570	COG1131	(ABC) transporter
C1H20_RS19575	COG0025	NhaP-type Na H and K H
C1H20_RS19580	COG3795	YCII-related domain
C1H20_RS19585	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1H20_RS19590	COG1573	uracil-dna glycosylase
C1H20_RS19605	COG3384	dioxygenase
C1H20_RS19610	COG0583	DNA-binding transcription factor activity
C1H20_RS19620	COG0667	Aldo Keto reductase
C1H20_RS19630	COG3590	peptidase
C1H20_RS19645	COG0531	amino acid
C1H20_RS19660	COG2972	Histidine kinase
C1H20_RS19680	COG1335	isochorismatase
C1H20_RS19685	COG3685	Protein conserved in bacteria
C1H20_RS19690	COG3685	Protein conserved in bacteria
C1H20_RS19695	COG3546	catalase activity
C1H20_RS19725	COG2204	response regulator
C1H20_RS19735	COG1271	oxidase subunit
C1H20_RS19740	COG1294	oxidase, subunit
C1H20_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS19760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1H20_RS19780	COG1132	(ABC) transporter
C1H20_RS19805	COG1063	alcohol dehydrogenase
C1H20_RS19845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1H20_RS19905	COG0251	oxidation-reduction process
C1H20_RS19925	COG0667	Aldo Keto reductase
C1H20_RS19930	COG0583	DNA-binding transcription factor activity
C1H20_RS19955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1H20_RS19965	COG1560	Kdo2-lipid A biosynthetic process
C1H20_RS19975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1H20_RS20010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1H20_RS20010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1H20_RS20020	COG0242	peptide deformylase activity
C1H20_RS20025	COG1652	LysM domain
C1H20_RS20030	COG0758	DNA mediated transformation
C1H20_RS20050	COG1754	DNA topoisomerase type I activity
C1H20_RS20050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1H20_RS20070	COG3706	GGDEF domain
C1H20_RS20070	COG5001	Diguanylate cyclase
C1H20_RS20070	COG2203	Gaf domain
C1H20_RS20070	COG4251	negative regulation of phosphorylation
C1H20_RS20075	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS20085	COG0616	signal peptide processing
C1H20_RS20090	COG0534	Mate efflux family protein
C1H20_RS20105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1H20_RS20110	COG0625	glutathione transferase activity
C1H20_RS20125	COG1252	NADH dehydrogenase
C1H20_RS20130	COG2860	membrane
C1H20_RS20135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1H20_RS20145	COG3437	response regulator, receiver
C1H20_RS20150	COG2177	Part of the ABC transporter FtsEX involved in
C1H20_RS20155	COG2884	Cell division ATP-binding protein ftsE
C1H20_RS20165	COG3118	belongs to the thioredoxin family
C1H20_RS20170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1H20_RS20215	COG1473	amidohydrolase
C1H20_RS20220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1H20_RS20260	COG4941	Belongs to the sigma-70 factor family
C1H20_RS20265	COG5383	Protein conserved in bacteria
C1H20_RS20305	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C1H20_RS20310	COG3501	Rhs element vgr protein
C1H20_RS20310	COG3409	Peptidoglycan-binding domain 1 protein
C1H20_RS20325	COG3023	N-Acetylmuramoyl-L-alanine amidase
C1H20_RS20335	COG4948	Mandelate Racemase Muconate Lactonizing
C1H20_RS20345	COG0531	amino acid
C1H20_RS20360	COG4682	membrane
C1H20_RS20365	COG2133	pyrroloquinoline quinone binding
C1H20_RS20375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1H20_RS20390	COG1610	YqeY-like protein
C1H20_RS20395	COG1295	ribonuclease BN
C1H20_RS20400	COG0358	DNA primase activity
C1H20_RS20450	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C1H20_RS20465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1H20_RS20515	COG0739	heme binding
C1H20_RS20535	COG0708	Exodeoxyribonuclease III
C1H20_RS20550	COG1192	Involved in chromosome partitioning
C1H20_RS20555	COG1475	DNA binding
C1H20_RS20575	COG0463	Glycosyl transferase, family 2
C1H20_RS20600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1H20_RS20625	COG4221	oxidoreductase activity
C1H20_RS20630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1H20_RS20630	COG2755	lipolytic protein G-D-S-L family
C1H20_RS20645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1H20_RS20650	COG3039	Transposase
C1H20_RS20655	COG1166	arginine decarboxylase activity
C1H20_RS20680	COG2960	long-chain fatty acid transporting porin activity
C1H20_RS20685	COG0606	chelatase, subunit chli
C1H20_RS20700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1H20_RS20735	COG1690	Belongs to the RtcB family
C1H20_RS20775	COG1090	epimerase
C1H20_RS20795	COG0642	Histidine kinase
C1H20_RS20815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1H20_RS20840	COG1011	Hydrolase
C1H20_RS20845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1H20_RS20865	COG2197	response regulator
C1H20_RS20870	COG4585	Histidine kinase
C1H20_RS20880	COG1136	(ABC) transporter
C1H20_RS20905	COG0697	spore germination
C1H20_RS20925	COG0180	Tryptophanyl-tRNA synthetase
C1H20_RS20930	COG3237	CsbD-like
C1H20_RS21005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C1H20_RS21005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C1H20_RS21045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1H20_RS21070	COG1199	ATP-dependent helicase activity
C1H20_RS21135	COG0625	glutathione transferase activity
C1H20_RS21175	COG4555	ABC transporter
C1H20_RS21185	COG1476	TRANSCRIPTIONal
C1H20_RS21200	COG1230	cation diffusion facilitator family transporter
C1H20_RS21210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1H20_RS21215	COG1131	(ABC) transporter
C1H20_RS21220	COG0842	Transport permease protein
C1H20_RS21230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1H20_RS21245	COG1607	acyl-coa hydrolase
C1H20_RS21260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1H20_RS21270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1H20_RS21280	COG0045	succinate-CoA ligase (ADP-forming) activity
C1H20_RS21280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1H20_RS21280	COG1042	CoA-binding domain protein
C1H20_RS21290	COG2239	Acts as a magnesium transporter
C1H20_RS21305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1H20_RS21310	COG3387	PFAM Glycoside hydrolase 15-related
C1H20_RS21330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1H20_RS21340	COG0463	Glycosyl transferase, family 2
C1H20_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS21385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C1H20_RS21400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1H20_RS21475	COG0210	DNA helicase
C1H20_RS21485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS21490	COG0583	DNA-binding transcription factor activity
C1H20_RS21495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1H20_RS21520	COG2159	amidohydrolase
C1H20_RS21590	COG3540	Alkaline phosphatase
C1H20_RS21620	COG2091	lysine biosynthetic process via aminoadipic acid
C1H20_RS21670	COG1940	carbohydrate kinase activity
C1H20_RS21680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1H20_RS21695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1H20_RS21700	COG3162	membrane
C1H20_RS21740	COG3507	Belongs to the glycosyl hydrolase 43 family
C1H20_RS21755	COG1028	Short-chain dehydrogenase reductase Sdr
C1H20_RS21760	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1H20_RS21765	COG4948	Mandelate Racemase Muconate Lactonizing
C1H20_RS21770	COG3254	rhamnose metabolic process
C1H20_RS21775	COG0738	Major facilitator superfamily
C1H20_RS21780	COG1414	Transcriptional regulator
C1H20_RS21800	COG0784	Response regulator, receiver
C1H20_RS21800	COG2205	protein histidine kinase activity
C1H20_RS21810	COG3459	Glycosyltransferase 36 associated
C1H20_RS21815	COG2211	Major facilitator Superfamily
C1H20_RS21820	COG3265	gluconokinase activity
C1H20_RS21825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1H20_RS21850	COG2911	Protein conserved in bacteria
C1H20_RS21855	COG0729	surface antigen
C1H20_RS21870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1H20_RS21880	COG0519	Catalyzes the synthesis of GMP from XMP
C1H20_RS21880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1H20_RS21890	COG0805	protein transport
C1H20_RS21910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1H20_RS21955	COG3661	Belongs to the glycosyl hydrolase 67 family
C1H20_RS21965	COG4948	Mandelate Racemase Muconate Lactonizing
C1H20_RS21975	COG1472	Belongs to the glycosyl hydrolase 3 family
C1H20_RS21980	COG0246	Mannitol dehydrogenase
C1H20_RS22020	COG3386	PFAM SMP-30 Gluconolaconase
C1H20_RS22055	COG3250	beta-galactosidase activity
C1H20_RS22065	COG3693	PFAM glycoside hydrolase, family 10
C1H20_RS22080	COG2211	Major facilitator Superfamily
C1H20_RS22120	COG2937	Belongs to the GPAT DAPAT family
C1H20_RS22155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C1H20_RS22175	COG0210	DNA helicase
C1H20_RS22275	COG3135	benzoate transporter
C1H20_RS22300	COG0676	glucose-6-phosphate 1-epimerase activity
C1H20_RS22320	COG0730	response to heat
C1H20_RS22345	COG0302	gtp cyclohydrolase
C1H20_RS22360	COG1566	PFAM secretion protein HlyD family protein
C1H20_RS22370	COG1289	transmembrane transporter activity
C1H20_RS22375	COG0477	Major facilitator Superfamily
C1H20_RS22395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1H20_RS22475	COG0564	pseudouridine synthase activity
C1H20_RS22490	COG1192	Involved in chromosome partitioning
C1H20_RS22540	COG1074	ATP-dependent DNA helicase activity
C1H20_RS22545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1H20_RS22580	COG1127	ABC transporter
C1H20_RS22585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1H20_RS22590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1H20_RS22605	COG2853	Lipoprotein
C1H20_RS22615	COG0386	Belongs to the glutathione peroxidase family
C1H20_RS22625	COG1322	Protein conserved in bacteria
C1H20_RS22635	COG0604	alcohol dehydrogenase
C1H20_RS22640	COG0583	DNA-binding transcription factor activity
C1H20_RS22655	COG0531	amino acid
C1H20_RS22665	COG4206	TonB-dependent receptor
C1H20_RS22675	COG3706	GGDEF domain
C1H20_RS22685	COG3835	regulator
C1H20_RS22690	COG1929	Belongs to the glycerate kinase type-1 family
C1H20_RS22695	COG2271	Major facilitator Superfamily
C1H20_RS22715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1H20_RS22725	COG0861	Integral membrane protein TerC family
C1H20_RS22755	COG0584	glycerophosphoryl diester phosphodiesterase
C1H20_RS22770	COG0671	phosphoesterase, PA-phosphatase related
C1H20_RS22785	COG0726	polysaccharide deacetylase