locus-tag	class	description
JM952_RS00020	COG0187	DNA topoisomerase II activity
JM952_RS00030	COG0501	Belongs to the peptidase M48B family
JM952_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JM952_RS00105	COG0793	Belongs to the peptidase S41A family
JM952_RS00110	COG4942	peptidase
JM952_RS00120	COG2234	aminopeptidase activity
JM952_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_RS00150	COG1064	alcohol dehydrogenase
JM952_RS00165	COG0493	'glutamate synthase
JM952_RS00170	COG0067	glutamate synthase
JM952_RS00170	COG0069	glutamate synthase activity
JM952_RS00170	COG0070	glutamate synthase
JM952_RS00185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JM952_RS00195	COG1741	Belongs to the pirin family
JM952_RS00220	COG0583	DNA-binding transcription factor activity
JM952_RS00280	COG1205	dead DEAH box helicase
JM952_RS00280	COG1111	helicase
JM952_RS00285	COG3177	Filamentation induced by cAMP protein fic
JM952_RS00290	COG1272	protein, Hemolysin III
JM952_RS00360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JM952_RS00365	COG3237	CsbD-like
JM952_RS00410	COG0628	permease
JM952_RS00415	COG0657	acetylesterase activity
JM952_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_RS00430	COG0477	Major facilitator Superfamily
JM952_RS00470	COG0714	Associated with various cellular activities
JM952_RS00510	COG4772	TonB-dependent receptor
JM952_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
JM952_RS00580	COG3710	Transcriptional regulator
JM952_RS00600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_RS00685	COG0366	Alpha amylase catalytic
JM952_RS00690	COG0366	Alpha amylase catalytic
JM952_RS00730	COG2755	lipolytic protein G-D-S-L family
JM952_RS00740	COG2755	lipolytic protein G-D-S-L family
JM952_RS00740	COG0657	acetylesterase activity
JM952_RS00750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JM952_RS00765	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_RS00770	COG1609	Transcriptional regulator
JM952_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS00790	COG2755	lipolytic protein G-D-S-L family
JM952_RS00800	COG3186	Phenylalanine-4-hydroxylase
JM952_RS00805	COG1522	sequence-specific DNA binding
JM952_RS00820	COG1752	Esterase of the alpha-beta hydrolase superfamily
JM952_RS00830	COG1119	ATPase activity
JM952_RS00845	COG0517	IMP dehydrogenase activity
JM952_RS00845	COG1125	glycine betaine transport
JM952_RS00860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JM952_RS00865	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JM952_RS00895	COG0489	protein tyrosine kinase activity
JM952_RS00900	COG0588	phosphoglycerate mutase activity
JM952_RS00910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS00935	COG1881	PFAM PEBP family protein
JM952_RS00950	COG0174	glutamine synthetase
JM952_RS00955	COG0347	Belongs to the P(II) protein family
JM952_RS00960	COG0004	ammonium transporteR
JM952_RS00965	COG3852	Histidine kinase
JM952_RS00970	COG2204	response regulator
JM952_RS00980	COG2032	superoxide dismutase activity
JM952_RS00985	COG2032	superoxide dismutase activity
JM952_RS01000	COG0183	Belongs to the thiolase family
JM952_RS01040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JM952_RS01060	COG0028	Belongs to the TPP enzyme family
JM952_RS01065	COG4191	Histidine kinase
JM952_RS01070	COG2204	response regulator
JM952_RS01090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JM952_RS01105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_RS01110	COG3177	Filamentation induced by cAMP protein fic
JM952_RS01115	COG0596	Alpha beta hydrolase
JM952_RS01120	COG0727	PFAM Uncharacterised protein family (UPF0153)
JM952_RS01125	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_RS01130	COG0745	RESPONSE REGULATOR receiver
JM952_RS01145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_RS01160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM952_RS01175	COG0564	pseudouridine synthase activity
JM952_RS01200	COG0339	signal peptide processing
JM952_RS01230	COG0583	DNA-binding transcription factor activity
JM952_RS01235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JM952_RS01240	COG2224	Isocitrate lyase
JM952_RS01270	COG4770	biotin carboxylase activity
JM952_RS01275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JM952_RS01280	COG1960	acyl-CoA dehydrogenase activity
JM952_RS01345	COG0697	spore germination
JM952_RS01355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JM952_RS01365	COG1846	Transcriptional regulator
JM952_RS01370	COG1764	response to oxidative stress
JM952_RS01400	COG0656	L-ascorbic acid biosynthetic process
JM952_RS01405	COG2130	NADP-dependent
JM952_RS01420	COG1187	pseudouridine synthase activity
JM952_RS01430	COG1643	Atp-dependent helicase
JM952_RS01435	COG0840	transmembrane signaling receptor activity
JM952_RS01440	COG4807	Protein conserved in bacteria
JM952_RS01445	COG2351	hydroxyisourate hydrolase activity
JM952_RS01450	COG2072	flavoprotein involved in K transport
JM952_RS01470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JM952_RS01500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS01515	COG1957	nucleoside hydrolase
JM952_RS01525	COG2252	PERMEase
JM952_RS01545	COG0084	hydrolase, TatD family'
JM952_RS01555	COG0583	DNA-binding transcription factor activity
JM952_RS01560	COG2814	Major facilitator Superfamily
JM952_RS01585	COG1902	pentaerythritol trinitrate reductase activity
JM952_RS01610	COG0300	oxidoreductase activity
JM952_RS01620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JM952_RS01625	COG0583	DNA-binding transcription factor activity
JM952_RS01655	COG0702	epimerase
JM952_RS01660	COG1733	regulation of RNA biosynthetic process
JM952_RS01670	COG0840	transmembrane signaling receptor activity
JM952_RS01785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JM952_RS01845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JM952_RS01870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JM952_RS01875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JM952_RS01885	COG3485	protocatechuate 3,4-dioxygenase
JM952_RS01890	COG3485	protocatechuate 3,4-dioxygenase
JM952_RS01900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_RS01905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JM952_RS01915	COG1414	Transcriptional regulator
JM952_RS01925	COG0657	acetylesterase activity
JM952_RS01945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JM952_RS01995	COG1040	competence protein
JM952_RS02010	COG0582	viral genome integration into host DNA
JM952_RS02020	COG4774	siderophore transport
JM952_RS02025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JM952_RS02040	COG4206	TonB-dependent receptor
JM952_RS02060	COG3264	Mechanosensitive ion channel
JM952_RS02060	COG1511	domain protein
JM952_RS02075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JM952_RS02080	COG2354	Protein conserved in bacteria
JM952_RS02085	COG1649	PFAM Uncharacterised BCR, COG1649
JM952_RS02095	COG0297	glycogen (starch) synthase activity
JM952_RS02105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JM952_RS02130	COG0702	epimerase
JM952_RS02165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS02180	COG0513	Belongs to the DEAD box helicase family
JM952_RS02190	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM952_RS02205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JM952_RS02220	COG3104	oligopeptide transport
JM952_RS02240	COG2852	Protein conserved in bacteria
JM952_RS02265	COG1320	monovalent cation:proton antiporter activity
JM952_RS02270	COG2212	antiporter activity
JM952_RS02280	COG0651	ATP synthesis coupled electron transport
JM952_RS02285	COG1006	Multisubunit Na H antiporter MnhC subunit
JM952_RS02290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JM952_RS02290	COG2111	Na H antiporter
JM952_RS02365	COG0436	Aminotransferase
JM952_RS02380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JM952_RS02485	COG2816	NAD+ diphosphatase activity
JM952_RS02490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JM952_RS02525	COG2814	Major facilitator Superfamily
JM952_RS02535	COG1289	transmembrane transporter activity
JM952_RS02540	COG0151	Belongs to the GarS family
JM952_RS02555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JM952_RS02560	COG2267	carboxylic ester hydrolase activity
JM952_RS02565	COG0671	phosphoesterase, PA-phosphatase related
JM952_RS02565	COG2453	phosphatase
JM952_RS02590	COG4589	Belongs to the CDS family
JM952_RS02605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JM952_RS02640	COG0439	Biotin carboxylase
JM952_RS02650	COG0511	ligase activity, forming carbon-carbon bonds
JM952_RS02665	COG1324	tolerance protein
JM952_RS02670	COG2356	endonuclease I
JM952_RS02685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JM952_RS02700	COG3039	Transposase
JM952_RS02705	COG1196	nuclear chromosome segregation
JM952_RS02750	COG3039	Transposase
JM952_RS02755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JM952_RS02780	COG3386	PFAM SMP-30 Gluconolaconase
JM952_RS02795	COG3712	iron ion homeostasis
JM952_RS02835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JM952_RS02860	COG2353	YceI-like domain
JM952_RS02915	COG1802	Transcriptional regulator
JM952_RS03030	COG0435	Glutathione S-transferase
JM952_RS03090	COG2409	Drug exporters of the RND superfamily
JM952_RS03100	COG1506	peptidase
JM952_RS03100	COG0823	Involved in the tonB-independent uptake of proteins
JM952_RS03115	COG1959	2 iron, 2 sulfur cluster binding
JM952_RS03150	COG0697	spore germination
JM952_RS03165	COG4305	rare lipoprotein A
JM952_RS03170	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_RS03180	COG1113	amino acid transport
JM952_RS03245	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_RS03245	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_RS03250	COG0659	secondary active sulfate transmembrane transporter activity
JM952_RS03270	COG0471	metal ion transport
JM952_RS03270	COG3273	potassium ion transport
JM952_RS03285	COG3275	phosphorelay sensor kinase activity
JM952_RS03325	COG1505	serine-type exopeptidase activity
JM952_RS03340	COG0436	Aminotransferase
JM952_RS03350	COG2832	Protein of unknown function (DUF454)
JM952_RS03410	COG2226	methyltransferase
JM952_RS03415	COG3300	MHYT domain
JM952_RS03415	COG5001	Diguanylate cyclase
JM952_RS03420	COG0308	aminopeptidase N
JM952_RS03455	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JM952_RS03470	COG3284	Transcriptional regulator
JM952_RS03475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_RS03480	COG1077	Cell shape determining protein MreB Mrl
JM952_RS03490	COG1792	Involved in formation and maintenance of cell shape
JM952_RS03505	COG0772	Belongs to the SEDS family
JM952_RS03560	COG2951	lytic endotransglycosylase activity
JM952_RS03565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JM952_RS03570	COG1686	Belongs to the peptidase S11 family
JM952_RS03615	COG1056	cytidyltransferase-related domain
JM952_RS03615	COG1051	belongs to the nudix hydrolase family
JM952_RS03650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JM952_RS03655	COG0673	inositol 2-dehydrogenase activity
JM952_RS03660	COG2823	Periplasmic or secreted lipoprotein
JM952_RS03665	COG4251	negative regulation of phosphorylation
JM952_RS03670	COG0784	Response regulator, receiver
JM952_RS03675	COG4191	Histidine kinase
JM952_RS03680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JM952_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS03730	COG1459	type II secretion system
JM952_RS03745	COG2165	general secretion pathway protein
JM952_RS03750	COG4795	General secretion pathway protein
JM952_RS03775	COG2188	Transcriptional regulator
JM952_RS03785	COG1609	Transcriptional regulator
JM952_RS03790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JM952_RS03795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JM952_RS03835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JM952_RS03845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JM952_RS03870	COG2205	protein histidine kinase activity
JM952_RS03890	COG0583	DNA-binding transcription factor activity
JM952_RS03910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JM952_RS03925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JM952_RS03935	COG0697	spore germination
JM952_RS03945	COG1307	EDD domain protein, DegV family
JM952_RS03985	COG0402	S-adenosylhomocysteine deaminase activity
JM952_RS04005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JM952_RS04025	COG0436	Aminotransferase
JM952_RS04060	COG2211	Major facilitator Superfamily
JM952_RS04065	COG1609	Transcriptional regulator
JM952_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS04075	COG2851	Citrate transporter
JM952_RS04090	COG0642	Histidine kinase
JM952_RS04100	COG2197	response regulator
JM952_RS04110	COG4191	Histidine kinase
JM952_RS04150	COG1560	Kdo2-lipid A biosynthetic process
JM952_RS04155	COG1519	Transferase
JM952_RS04160	COG1538	Outer membrane efflux protein
JM952_RS04165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JM952_RS04175	COG5001	Diguanylate cyclase
JM952_RS04175	COG3300	MHYT domain
JM952_RS04185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JM952_RS04195	COG2226	methyltransferase
JM952_RS04230	COG0405	Gamma-glutamyltransferase
JM952_RS04235	COG0840	transmembrane signaling receptor activity
JM952_RS04240	COG0823	Involved in the tonB-independent uptake of proteins
JM952_RS04240	COG1506	peptidase
JM952_RS04240	COG4946	Tricorn protease homolog
JM952_RS04250	COG3710	Transcriptional regulator
JM952_RS04275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JM952_RS04285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JM952_RS04315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JM952_RS04325	COG3781	membrane
JM952_RS04330	COG0671	phosphoesterase, PA-phosphatase related
JM952_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS04350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JM952_RS04355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JM952_RS04385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JM952_RS04415	COG1773	rubredoxin
JM952_RS04420	COG2912	Transglutaminase-like superfamily
JM952_RS04440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JM952_RS04465	COG0006	proline dipeptidase activity
JM952_RS04490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JM952_RS04500	COG0346	lactoylglutathione lyase activity
JM952_RS04510	COG1561	YicC-like family, N-terminal region
JM952_RS04525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JM952_RS04535	COG0583	DNA-binding transcription factor activity
JM952_RS04550	COG2271	Major facilitator Superfamily
JM952_RS04565	COG2721	sulfolactate sulfo-lyase activity
JM952_RS04575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JM952_RS04600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JM952_RS04630	COG0714	Associated with various cellular activities
JM952_RS04650	COG2304	oxidoreductase activity
JM952_RS04660	COG1301	dicarboxylic acid transport
JM952_RS04665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JM952_RS04670	COG0596	Alpha beta hydrolase
JM952_RS04680	COG0739	heme binding
JM952_RS04685	COG1376	ErfK ybiS ycfS ynhG family protein
JM952_RS04715	COG4149	molybdate abc transporter
JM952_RS04720	COG0725	ABC transporter, periplasmic molybdate-binding protein
JM952_RS04740	COG3047	cAMP biosynthetic process
JM952_RS04755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JM952_RS04785	COG0469	pyruvate kinase activity
JM952_RS04790	COG3588	fructose-bisphosphate aldolase
JM952_RS04795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JM952_RS04825	COG0784	Response regulator, receiver
JM952_RS04825	COG2198	Histidine kinase
JM952_RS04825	COG2205	protein histidine kinase activity
JM952_RS04855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JM952_RS04865	COG0529	Catalyzes the synthesis of activated sulfate
JM952_RS04865	COG2895	sulfate adenylyltransferase (ATP) activity
JM952_RS04870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_RS04875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_RS04880	COG0308	aminopeptidase N
JM952_RS04890	COG1115	amino acid carrier protein
JM952_RS04895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM952_RS04900	COG2272	Belongs to the type-B carboxylesterase lipase family
JM952_RS04905	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_RS04910	COG3250	beta-galactosidase activity
JM952_RS04925	COG1609	Transcriptional regulator
JM952_RS04955	COG3273	potassium ion transport
JM952_RS04955	COG0471	metal ion transport
JM952_RS05085	COG2003	Belongs to the UPF0758 family
JM952_RS05205	COG0745	RESPONSE REGULATOR receiver
JM952_RS05235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JM952_RS05240	COG1459	type II secretion system
JM952_RS05295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JM952_RS05295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JM952_RS05305	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_RS05310	COG0564	pseudouridine synthase activity
JM952_RS05330	COG0840	transmembrane signaling receptor activity
JM952_RS05350	COG3387	PFAM Glycoside hydrolase 15-related
JM952_RS05355	COG1877	trehalose-phosphatase activity
JM952_RS05400	COG1116	anion transmembrane transporter activity
JM952_RS05405	COG0542	response to heat
JM952_RS05420	COG4206	TonB-dependent receptor
JM952_RS05440	COG1797	cobyrinic acid a,c-diamide synthase activity
JM952_RS05445	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JM952_RS05475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JM952_RS05495	COG0019	diaminopimelate decarboxylase activity
JM952_RS05500	COG4264	IucA IucC family
JM952_RS05505	COG2814	Major facilitator Superfamily
JM952_RS05510	COG4264	IucA IucC family
JM952_RS05520	COG4772	TonB-dependent receptor
JM952_RS05530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JM952_RS05530	COG4651	solute:proton antiporter activity
JM952_RS05560	COG0488	(ABC) transporter
JM952_RS05580	COG2755	lipolytic protein G-D-S-L family
JM952_RS05580	COG0657	acetylesterase activity
JM952_RS05600	COG0477	Major facilitator Superfamily
JM952_RS05665	COG2255	four-way junction helicase activity
JM952_RS05670	COG0824	Thioesterase
JM952_RS05680	COG0848	biopolymer transport protein
JM952_RS05695	COG2885	chlorophyll binding
JM952_RS05705	COG0602	queuosine metabolic process
JM952_RS05750	COG0583	DNA-binding transcription factor activity
JM952_RS05775	COG1187	pseudouridine synthase activity
JM952_RS05790	COG0514	ATP-dependent DNA helicase (RecQ)
JM952_RS05795	COG0783	Belongs to the Dps family
JM952_RS05800	COG1643	Atp-dependent helicase
JM952_RS05850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JM952_RS05860	COG1215	transferase activity, transferring glycosyl groups
JM952_RS05865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JM952_RS05875	COG1199	ATP-dependent helicase activity
JM952_RS05895	COG1397	ADP-ribosylglycohydrolase
JM952_RS05905	COG0189	ligase activity
JM952_RS05920	COG0835	chemotaxis
JM952_RS05925	COG0840	transmembrane signaling receptor activity
JM952_RS05930	COG0643	Histidine kinase
JM952_RS05930	COG2198	Histidine kinase
JM952_RS05930	COG0784	Response regulator, receiver
JM952_RS05960	COG1595	DNA-templated transcription, initiation
JM952_RS05965	COG2304	oxidoreductase activity
JM952_RS05970	COG1446	asparaginase
JM952_RS06015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JM952_RS06025	COG3645	SOS response
JM952_RS06065	COG3537	Alpha-1,2-mannosidase
JM952_RS06075	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_RS06085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JM952_RS06090	COG1388	LysM domain
JM952_RS06090	COG3858	chitin binding
JM952_RS06105	COG0837	glucose binding
JM952_RS06110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JM952_RS06120	COG0494	nUDIX hydrolase
JM952_RS06125	COG1218	3'(2'),5'-bisphosphate nucleotidase
JM952_RS06130	COG3956	TIGRFAM MazG family protein
JM952_RS06145	COG0330	HflC and HflK could
JM952_RS06190	COG1960	acyl-CoA dehydrogenase activity
JM952_RS06200	COG1309	transcriptional regulator
JM952_RS06205	COG4771	TonB-dependent receptor
JM952_RS06215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JM952_RS06225	COG0463	Glycosyl transferase, family 2
JM952_RS06230	COG0516	GMP reductase activity
JM952_RS06230	COG0517	IMP dehydrogenase activity
JM952_RS06235	COG2982	Protein involved in outer membrane biogenesis
JM952_RS06240	COG1272	protein, Hemolysin III
JM952_RS06255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_RS06260	COG0626	cystathionine gamma-synthase activity
JM952_RS06265	COG0460	homoserine dehydrogenase
JM952_RS06265	COG0527	aspartate kinase activity
JM952_RS06280	COG1760	l-serine dehydratase
JM952_RS06300	COG2353	YceI-like domain
JM952_RS06320	COG0477	Major facilitator Superfamily
JM952_RS06360	COG1842	Phage shock protein A
JM952_RS06385	COG0754	glutathionylspermidine amidase activity
JM952_RS06395	COG2814	Major facilitator Superfamily
JM952_RS06455	COG0531	amino acid
JM952_RS06460	COG2197	response regulator
JM952_RS06485	COG1113	amino acid transport
JM952_RS06490	COG1271	oxidase subunit
JM952_RS06495	COG1294	oxidase, subunit
JM952_RS06505	COG2239	Acts as a magnesium transporter
JM952_RS06510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JM952_RS06515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_RS06535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_RS06550	COG1137	ATPase activity
JM952_RS06565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JM952_RS06575	COG0271	Belongs to the BolA IbaG family
JM952_RS06600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JM952_RS06620	COG0628	permease
JM952_RS06630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JM952_RS06645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM952_RS06650	COG1555	photosystem II stabilization
JM952_RS06695	COG4774	siderophore transport
JM952_RS06710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JM952_RS06715	COG0719	Fe-S assembly protein
JM952_RS06720	COG0396	ATPase activity
JM952_RS06725	COG0719	Fe-S assembly protein
JM952_RS06740	COG0693	protein deglycase activity
JM952_RS06775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JM952_RS06805	COG0519	Catalyzes the synthesis of GMP from XMP
JM952_RS06810	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JM952_RS06830	COG1764	response to oxidative stress
JM952_RS06840	COG0384	phenazine biosynthesis protein PhzF
JM952_RS06845	COG0384	phenazine biosynthesis protein PhzF
JM952_RS06850	COG0527	aspartate kinase activity
JM952_RS06875	COG0142	geranyltranstransferase activity
JM952_RS06880	COG0629	single-stranded DNA binding
JM952_RS06890	COG3713	MltA-interacting MipA family protein
JM952_RS06900	COG0745	RESPONSE REGULATOR receiver
JM952_RS06905	COG4251	negative regulation of phosphorylation
JM952_RS06910	COG3706	GGDEF domain
JM952_RS06910	COG4251	negative regulation of phosphorylation
JM952_RS06910	COG5001	Diguanylate cyclase
JM952_RS06910	COG2203	Gaf domain
JM952_RS06915	COG0604	alcohol dehydrogenase
JM952_RS06920	COG2080	2 iron, 2 sulfur cluster binding
JM952_RS06925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JM952_RS06930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JM952_RS06935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JM952_RS06940	COG0746	molybdenum cofactor guanylyltransferase activity
JM952_RS06970	COG2879	small protein
JM952_RS06975	COG1966	Carbon starvation protein
JM952_RS06980	COG1741	Belongs to the pirin family
JM952_RS07000	COG1741	Belongs to the pirin family
JM952_RS07020	COG3590	peptidase
JM952_RS07025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS07035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JM952_RS07045	COG0835	chemotaxis
JM952_RS07050	COG0840	transmembrane signaling receptor activity
JM952_RS07055	COG0643	Histidine kinase
JM952_RS07055	COG2198	Histidine kinase
JM952_RS07065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JM952_RS07080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JM952_RS07085	COG0745	RESPONSE REGULATOR receiver
JM952_RS07090	COG2205	protein histidine kinase activity
JM952_RS07095	COG4452	Inner membrane protein CreD
JM952_RS07130	COG0735	belongs to the Fur family
JM952_RS07145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_RS07155	COG1309	transcriptional regulator
JM952_RS07160	COG0667	Aldo Keto reductase
JM952_RS07175	COG2207	Transcriptional regulator
JM952_RS07195	COG0583	DNA-binding transcription factor activity
JM952_RS07200	COG2814	Major facilitator Superfamily
JM952_RS07235	COG3383	formate dehydrogenase (NAD+) activity
JM952_RS07245	COG1271	oxidase subunit
JM952_RS07250	COG1294	oxidase, subunit
JM952_RS07350	COG5001	Diguanylate cyclase
JM952_RS07350	COG5002	protein histidine kinase activity
JM952_RS07355	COG1187	pseudouridine synthase activity
JM952_RS07380	COG0475	glutathione-regulated potassium exporter activity
JM952_RS07385	COG1132	(ABC) transporter
JM952_RS07440	COG2155	Conserved Protein
JM952_RS07450	COG3118	belongs to the thioredoxin family
JM952_RS07475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JM952_RS07505	COG2968	Membrane
JM952_RS07520	COG3164	Protein of unknown function
JM952_RS07530	COG0312	modulator of DNA gyrase
JM952_RS07540	COG0312	modulator of DNA gyrase
JM952_RS07560	COG0142	geranyltranstransferase activity
JM952_RS07575	COG1785	Belongs to the alkaline phosphatase family
JM952_RS07580	COG1301	dicarboxylic acid transport
JM952_RS07585	COG4106	trans-aconitate 2-methyltransferase activity
JM952_RS07600	COG4191	Histidine kinase
JM952_RS07630	COG0791	NLP P60 protein
JM952_RS07635	COG0791	NLP P60 protein
JM952_RS07640	COG1047	Peptidyl-prolyl cis-trans
JM952_RS07645	COG2311	Membrane
JM952_RS07650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_RS07655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM952_RS07675	COG3590	peptidase
JM952_RS07680	COG3590	peptidase
JM952_RS07700	COG0489	protein tyrosine kinase activity
JM952_RS07725	COG0412	Dienelactone hydrolase
JM952_RS07740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_RS07755	COG0494	nUDIX hydrolase
JM952_RS07765	COG0433	COG0433 Predicted ATPase
JM952_RS07790	COG2890	protein-(glutamine-N5) methyltransferase activity
JM952_RS07805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JM952_RS07810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JM952_RS07910	COG4221	oxidoreductase activity
JM952_RS07930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JM952_RS07950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JM952_RS07955	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JM952_RS07975	COG0839	Belongs to the complex I subunit 6 family
JM952_RS07995	COG1007	ATP synthesis coupled electron transport
JM952_RS08010	COG0195	Participates in both transcription termination and antitermination
JM952_RS08070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JM952_RS08080	COG2095	MarC family integral membrane protein
JM952_RS08090	COG1611	Belongs to the LOG family
JM952_RS08095	COG3275	phosphorelay sensor kinase activity
JM952_RS08155	COG3505	Type IV secretory pathway VirD4
JM952_RS08175	COG2948	multi-organism process
JM952_RS08195	COG3702	type iv secretory pathway
JM952_RS08225	COG3501	Rhs element vgr protein
JM952_RS08225	COG3409	Peptidoglycan-binding domain 1 protein
JM952_RS08270	COG0366	Alpha amylase catalytic
JM952_RS08285	COG1082	Xylose isomerase domain protein TIM barrel
JM952_RS08315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JM952_RS08385	COG0438	transferase activity, transferring glycosyl groups
JM952_RS08395	COG2244	polysaccharide biosynthetic process
JM952_RS08400	COG0438	transferase activity, transferring glycosyl groups
JM952_RS08425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_RS08435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_RS08465	COG1960	acyl-CoA dehydrogenase activity
JM952_RS08510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JM952_RS08520	COG4191	Histidine kinase
JM952_RS08520	COG0784	Response regulator, receiver
JM952_RS08540	COG0552	protein localization to endoplasmic reticulum
JM952_RS08550	COG3938	Belongs to the proline racemase family
JM952_RS08570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JM952_RS08580	COG0006	proline dipeptidase activity
JM952_RS08605	COG0531	amino acid
JM952_RS08640	COG4206	TonB-dependent receptor
JM952_RS08650	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_RS08655	COG0823	Involved in the tonB-independent uptake of proteins
JM952_RS08655	COG1506	peptidase
JM952_RS08665	COG4206	TonB-dependent receptor
JM952_RS08710	COG0326	Molecular chaperone. Has ATPase activity
JM952_RS08715	COG0742	ribosomal rna small subunit methyltransferase
JM952_RS08730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JM952_RS08735	COG0405	Gamma-glutamyltransferase
JM952_RS08740	COG3291	Pkd domain containing protein
JM952_RS08770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JM952_RS08790	COG1862	Preprotein translocase
JM952_RS08800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JM952_RS08815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM952_RS08815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM952_RS08820	COG1105	Belongs to the carbohydrate kinase PfkB family
JM952_RS08825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_RS08825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JM952_RS08830	COG1609	Transcriptional regulator
JM952_RS08835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_RS08840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_RS08850	COG2902	Dehydrogenase
JM952_RS08855	COG1609	Transcriptional regulator
JM952_RS08855	COG2207	Transcriptional regulator
JM952_RS08860	COG1335	isochorismatase
JM952_RS08865	COG0477	Major facilitator Superfamily
JM952_RS08875	COG0784	Response regulator, receiver
JM952_RS08875	COG2205	protein histidine kinase activity
JM952_RS08875	COG5002	protein histidine kinase activity
JM952_RS08880	COG2733	membrane
JM952_RS08890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JM952_RS08895	COG2223	nitrite transmembrane transporter activity
JM952_RS08905	COG0243	molybdopterin cofactor binding
JM952_RS08915	COG0477	Major facilitator Superfamily
JM952_RS08920	COG2703	oxygen carrier activity
JM952_RS08930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_RS08935	COG0174	glutamine synthetase
JM952_RS08940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM952_RS08975	COG3842	ATPase activity
JM952_RS08985	COG1176	ABC-type spermidine putrescine transport system, permease component I
JM952_RS08990	COG1177	transmembrane transport
JM952_RS09000	COG1012	belongs to the aldehyde dehydrogenase family
JM952_RS09015	COG4535	Mg2 and Co2 transporter CorC
JM952_RS09035	COG1702	phosphate starvation-inducible protein PhoH
JM952_RS09055	COG0741	lytic transglycosylase activity
JM952_RS09060	COG0723	plastoquinol--plastocyanin reductase activity
JM952_RS09065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JM952_RS09070	COG2857	Cytochrome c1
JM952_RS09075	COG0625	glutathione transferase activity
JM952_RS09080	COG2969	positive regulation of protein catabolic process
JM952_RS09095	COG1201	RNA secondary structure unwinding
JM952_RS09105	COG0840	transmembrane signaling receptor activity
JM952_RS09110	COG0835	chemotaxis
JM952_RS09155	COG0582	viral genome integration into host DNA
JM952_RS09185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JM952_RS09200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JM952_RS09205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JM952_RS09205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JM952_RS09215	COG0860	N-Acetylmuramoyl-L-alanine amidase
JM952_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS09255	COG5001	Diguanylate cyclase
JM952_RS09255	COG3300	MHYT domain
JM952_RS09260	COG2081	HI0933 family
JM952_RS09265	COG4681	YaeQ
JM952_RS09300	COG0513	Belongs to the DEAD box helicase family
JM952_RS09305	COG0488	(ABC) transporter
JM952_RS09320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JM952_RS09325	COG0483	inositol monophosphate 1-phosphatase activity
JM952_RS09340	COG3300	MHYT domain
JM952_RS09340	COG5001	Diguanylate cyclase
JM952_RS09345	COG1509	lysine 2,3-aminomutase activity
JM952_RS09360	COG0402	S-adenosylhomocysteine deaminase activity
JM952_RS09430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JM952_RS09460	COG2166	iron-sulfur cluster assembly
JM952_RS09475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JM952_RS09485	COG0137	argininosuccinate synthase activity
JM952_RS09490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM952_RS09495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JM952_RS09560	COG1294	oxidase, subunit
JM952_RS09570	COG4988	ABC transporter
JM952_RS09575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JM952_RS09640	COG0436	Aminotransferase
JM952_RS09660	COG1187	pseudouridine synthase activity
JM952_RS09665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JM952_RS09670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JM952_RS09675	COG2350	Protein conserved in bacteria
JM952_RS09700	COG2182	Extracellular solute-binding protein
JM952_RS09710	COG0395	ABC-type sugar transport system, permease component
JM952_RS09735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JM952_RS09740	COG2957	Belongs to the agmatine deiminase family
JM952_RS09760	COG0539	negative regulation of cytoplasmic translation
JM952_RS09775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JM952_RS09790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JM952_RS09795	COG0475	glutathione-regulated potassium exporter activity
JM952_RS09795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JM952_RS09835	COG2197	response regulator
JM952_RS09850	COG1335	isochorismatase
JM952_RS09865	COG2814	Major facilitator Superfamily
JM952_RS09880	COG1914	H( )-stimulated, divalent metal cation uptake system
JM952_RS09900	COG0668	transmembrane transport
JM952_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS09930	COG1183	phosphatidylcholine synthase activity
JM952_RS09940	COG3243	poly(R)-hydroxyalkanoic acid synthase
JM952_RS09955	COG0723	plastoquinol--plastocyanin reductase activity
JM952_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_RS09965	COG2183	response to ionizing radiation
JM952_RS09970	COG5001	Diguanylate cyclase
JM952_RS10035	COG0800	Aldolase
JM952_RS10040	COG0129	dihydroxy-acid dehydratase activity
JM952_RS10045	COG0363	glucosamine-6-phosphate deaminase activity
JM952_RS10055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JM952_RS10065	COG0354	folic acid binding
JM952_RS10080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JM952_RS10085	COG1053	succinate dehydrogenase
JM952_RS10095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JM952_RS10110	COG4591	ABC-type transport system involved in lipoprotein release permease component
JM952_RS10130	COG0811	peptide transport
JM952_RS10155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JM952_RS10170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JM952_RS10190	COG0582	viral genome integration into host DNA
JM952_RS10250	COG0583	DNA-binding transcription factor activity
JM952_RS10335	COG2003	Belongs to the UPF0758 family
JM952_RS10495	COG2951	lytic endotransglycosylase activity
JM952_RS10510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JM952_RS10530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JM952_RS10535	COG0629	single-stranded DNA binding
JM952_RS10585	COG1002	Type II restriction enzyme, methylase subunits
JM952_RS10590	COG1061	Type III restriction enzyme res subunit
JM952_RS10595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JM952_RS10610	COG5599	Phosphatase
JM952_RS10635	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JM952_RS10685	COG0840	transmembrane signaling receptor activity
JM952_RS10765	COG0428	transporter
JM952_RS10775	COG1530	ribonuclease E activity
JM952_RS10780	COG0840	transmembrane signaling receptor activity
JM952_RS10825	COG3279	Response regulator of the LytR AlgR family
JM952_RS10840	COG4191	Histidine kinase
JM952_RS10840	COG0784	Response regulator, receiver
JM952_RS10845	COG0840	transmembrane signaling receptor activity
JM952_RS10885	COG0840	transmembrane signaling receptor activity
JM952_RS10895	COG1238	metal cluster binding
JM952_RS10925	COG1733	regulation of RNA biosynthetic process
JM952_RS10940	COG1999	signal sequence binding
JM952_RS10955	COG3590	peptidase
JM952_RS11025	COG5001	Diguanylate cyclase
JM952_RS11035	COG2201	protein-glutamate methylesterase activity
JM952_RS11040	COG3685	Protein conserved in bacteria
JM952_RS11055	COG0579	oxidoreductase
JM952_RS11065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JM952_RS11075	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JM952_RS11095	COG0243	molybdopterin cofactor binding
JM952_RS11105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JM952_RS11110	COG2223	nitrite transmembrane transporter activity
JM952_RS11115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JM952_RS11125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JM952_RS11125	COG1648	precorrin-2 dehydrogenase activity
JM952_RS11135	COG0746	molybdenum cofactor guanylyltransferase activity
JM952_RS11140	COG0303	'Molybdopterin
JM952_RS11150	COG0708	Exodeoxyribonuclease III
JM952_RS11175	COG2124	cytochrome p450
JM952_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS11195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JM952_RS11210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_RS11245	COG1250	3-hydroxyacyl-CoA dehydrogenase
JM952_RS11245	COG1024	Enoyl-CoA hydratase
JM952_RS11250	COG0183	Belongs to the thiolase family
JM952_RS11255	COG0038	chloride channel
JM952_RS11260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JM952_RS11280	COG1674	ftsk spoiiie
JM952_RS11285	COG0492	ferredoxin-NADP+ reductase activity
JM952_RS11305	COG0542	response to heat
JM952_RS11325	COG2915	High frequency lysogenization protein hflD homolog
JM952_RS11360	COG4191	Histidine kinase
JM952_RS11380	COG0835	chemotaxis
JM952_RS11380	COG0784	Response regulator, receiver
JM952_RS11390	COG1558	bacterial-type flagellum-dependent cell motility
JM952_RS11395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JM952_RS11405	COG4787	bacterial-type flagellum-dependent cell motility
JM952_RS11425	COG3951	Flagellar rod assembly protein muramidase FlgJ
JM952_RS11425	COG1705	Flagellar rod assembly protein muramidase FlgJ
JM952_RS11435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JM952_RS11440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JM952_RS11445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JM952_RS11475	COG2201	protein-glutamate methylesterase activity
JM952_RS11505	COG0438	transferase activity, transferring glycosyl groups
JM952_RS11505	COG1216	Glycosyl transferase, family 2
JM952_RS11510	COG1677	Flagellar hook-basal body complex protein FliE
JM952_RS11570	COG1987	bacterial-type flagellum assembly
JM952_RS11575	COG1684	flagellar biosynthetic protein fliR
JM952_RS11630	COG2198	Histidine kinase
JM952_RS11630	COG0784	Response regulator, receiver
JM952_RS11630	COG0643	Histidine kinase
JM952_RS11725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JM952_RS11730	COG1360	Flagellar Motor Protein
JM952_RS11735	COG1192	Involved in chromosome partitioning
JM952_RS11740	COG0835	chemotaxis
JM952_RS11750	COG0745	RESPONSE REGULATOR receiver
JM952_RS11760	COG0840	transmembrane signaling receptor activity
JM952_RS11760	COG3290	protein histidine kinase activity
JM952_RS11775	COG0840	transmembrane signaling receptor activity
JM952_RS11785	COG0840	transmembrane signaling receptor activity
JM952_RS11790	COG0840	transmembrane signaling receptor activity
JM952_RS11795	COG0840	transmembrane signaling receptor activity
JM952_RS11800	COG0840	transmembrane signaling receptor activity
JM952_RS11825	COG0835	chemotaxis
JM952_RS11835	COG0840	transmembrane signaling receptor activity
JM952_RS11860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_RS11890	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_RS11895	COG1024	Enoyl-CoA hydratase
JM952_RS11900	COG2198	Histidine kinase
JM952_RS11900	COG2205	protein histidine kinase activity
JM952_RS11900	COG0784	Response regulator, receiver
JM952_RS11905	COG0784	Response regulator, receiver
JM952_RS11905	COG2198	Histidine kinase
JM952_RS11905	COG2205	protein histidine kinase activity
JM952_RS11925	COG3279	Response regulator of the LytR AlgR family
JM952_RS11945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JM952_RS11955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_RS11960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JM952_RS11970	COG0505	Belongs to the CarA family
JM952_RS11980	COG2258	MOSC domain
JM952_RS11985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JM952_RS12010	COG1024	Enoyl-CoA hydratase
JM952_RS12045	COG0277	FAD linked oxidase domain protein
JM952_RS12050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JM952_RS12065	COG0531	amino acid
JM952_RS12070	COG0531	amino acid
JM952_RS12100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JM952_RS12100	COG0140	phosphoribosyl-ATP diphosphatase activity
JM952_RS12120	COG0131	Imidazoleglycerol-phosphate dehydratase
JM952_RS12120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JM952_RS12135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JM952_RS12150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JM952_RS12170	COG0083	homoserine kinase activity
JM952_RS12185	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JM952_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
JM952_RS12240	COG0697	spore germination
JM952_RS12245	COG1794	racemase activity, acting on amino acids and derivatives
JM952_RS12255	COG0671	phosphoesterase, PA-phosphatase related
JM952_RS12270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JM952_RS12275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_RS12280	COG3706	GGDEF domain
JM952_RS12280	COG5001	Diguanylate cyclase
JM952_RS12280	COG4251	negative regulation of phosphorylation
JM952_RS12280	COG2203	Gaf domain
JM952_RS12290	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_RS12345	COG0860	N-Acetylmuramoyl-L-alanine amidase
JM952_RS12365	COG0477	Major facilitator Superfamily
JM952_RS12375	COG1070	Carbohydrate kinase
JM952_RS12385	COG1501	Belongs to the glycosyl hydrolase 31 family
JM952_RS12425	COG0800	Aldolase
JM952_RS12440	COG3734	2-keto-3-deoxy-galactonokinase
JM952_RS12445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JM952_RS12455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JM952_RS12470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JM952_RS12475	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JM952_RS12485	COG0352	thiamine-phosphate diphosphorylase activity
JM952_RS12485	COG0351	phosphomethylpyrimidine kinase
JM952_RS12510	COG0583	DNA-binding transcription factor activity
JM952_RS12515	COG1741	Belongs to the pirin family
JM952_RS12550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JM952_RS12560	COG4771	TonB-dependent receptor
JM952_RS12570	COG1546	Belongs to the CinA family
JM952_RS12575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JM952_RS12590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JM952_RS12595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JM952_RS12605	COG1534	Rna-binding protein
JM952_RS12620	COG1238	metal cluster binding
JM952_RS12635	COG2840	Smr protein MutS2
JM952_RS12695	COG2134	cdp-diacylglycerol pyrophosphatase
JM952_RS12720	COG1253	flavin adenine dinucleotide binding
JM952_RS12735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JM952_RS12740	COG0477	Major facilitator Superfamily
JM952_RS12745	COG1132	(ABC) transporter
JM952_RS12765	COG0438	transferase activity, transferring glycosyl groups
JM952_RS12770	COG0438	transferase activity, transferring glycosyl groups
JM952_RS12775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JM952_RS12805	COG2244	polysaccharide biosynthetic process
JM952_RS12820	COG3038	cytochrome b561
JM952_RS12855	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JM952_RS12875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_RS12890	COG4191	Histidine kinase
JM952_RS12890	COG0784	Response regulator, receiver
JM952_RS12895	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JM952_RS12945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JM952_RS13085	COG2003	Belongs to the UPF0758 family
JM952_RS13300	COG0583	DNA-binding transcription factor activity
JM952_RS13325	COG2003	Belongs to the UPF0758 family
JM952_RS13355	COG0583	DNA-binding transcription factor activity
JM952_RS13370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JM952_RS13380	COG0077	Prephenate dehydratase
JM952_RS13380	COG1605	Chorismate mutase
JM952_RS13390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JM952_RS13445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JM952_RS13455	COG4993	Dehydrogenase
JM952_RS13475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JM952_RS13485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JM952_RS13520	COG0316	Belongs to the HesB IscA family
JM952_RS13550	COG0288	reversible hydration of carbon dioxide
JM952_RS13575	COG2925	Exonuclease
JM952_RS13590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JM952_RS13610	COG0488	(ABC) transporter
JM952_RS13615	COG2264	protein methyltransferase activity
JM952_RS13650	COG0494	nUDIX hydrolase
JM952_RS13660	COG1024	Enoyl-CoA hydratase
JM952_RS13670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JM952_RS13675	COG0659	secondary active sulfate transmembrane transporter activity
JM952_RS13700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JM952_RS13705	COG0573	inorganic phosphate transmembrane transporter activity
JM952_RS13710	COG0581	inorganic phosphate transmembrane transporter activity
JM952_RS13720	COG0704	Plays a role in the regulation of phosphate uptake
JM952_RS13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM952_RS13755	COG0557	exoribonuclease II activity
JM952_RS13770	COG1960	acyl-CoA dehydrogenase activity
JM952_RS13775	COG2226	methyltransferase
JM952_RS13780	COG0646	methionine synthase
JM952_RS13780	COG1410	methionine synthase
JM952_RS13785	COG0646	methionine synthase
JM952_RS13785	COG1410	methionine synthase
JM952_RS13795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_RS13805	COG1609	Transcriptional regulator
JM952_RS13845	COG0386	Belongs to the glutathione peroxidase family
JM952_RS13855	COG1725	Transcriptional regulator
JM952_RS13860	COG1131	(ABC) transporter
JM952_RS13905	COG2850	peptidyl-arginine hydroxylation
JM952_RS13940	COG1132	(ABC) transporter
JM952_RS13945	COG0583	DNA-binding transcription factor activity
JM952_RS13950	COG2274	protein secretion by the type I secretion system
JM952_RS13975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JM952_RS13995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JM952_RS14000	COG1420	regulation of RNA biosynthetic process
JM952_RS14005	COG0497	DNA recombination
JM952_RS14015	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_RS14035	COG1404	Belongs to the peptidase S8 family
JM952_RS14140	COG3039	Transposase
JM952_RS14190	COG3706	GGDEF domain
JM952_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS14220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_RS14230	COG0583	DNA-binding transcription factor activity
JM952_RS14240	COG0415	Belongs to the DNA photolyase family
JM952_RS14245	COG0305	Participates in initiation and elongation during chromosome replication
JM952_RS14255	COG0367	asparagine synthase
JM952_RS14270	COG1960	acyl-CoA dehydrogenase activity
JM952_RS14285	COG0084	hydrolase, TatD family'
JM952_RS14290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JM952_RS14350	COG0386	Belongs to the glutathione peroxidase family
JM952_RS14355	COG0339	signal peptide processing
JM952_RS14390	COG3104	oligopeptide transport
JM952_RS14420	COG2814	Major facilitator Superfamily
JM952_RS14425	COG1566	PFAM secretion protein HlyD family protein
JM952_RS14465	COG4774	siderophore transport
JM952_RS14475	COG0367	asparagine synthase
JM952_RS14490	COG1393	Belongs to the ArsC family
JM952_RS14560	COG0528	UMP kinase activity
JM952_RS14570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JM952_RS14575	COG0575	Belongs to the CDS family
JM952_RS14585	COG0750	zinc metalloprotease
JM952_RS14640	COG1981	membrane
JM952_RS14660	COG1695	Transcriptional regulator
JM952_RS14685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JM952_RS14695	COG2040	homocysteine
JM952_RS14700	COG0833	amino acid
JM952_RS14705	COG0346	lactoylglutathione lyase activity
JM952_RS14730	COG2878	Part of a membrane complex involved in electron transport
JM952_RS14745	COG1595	DNA-templated transcription, initiation
JM952_RS14770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JM952_RS14785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JM952_RS14790	COG0251	oxidation-reduction process
JM952_RS14800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JM952_RS14800	COG0392	lysyltransferase activity
JM952_RS14835	COG2814	Major facilitator Superfamily
JM952_RS14840	COG1902	pentaerythritol trinitrate reductase activity
JM952_RS14865	COG2824	Alkylphosphonate utilization operon protein PhnA
JM952_RS14875	COG1047	Peptidyl-prolyl cis-trans
JM952_RS14925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JM952_RS14935	COG5487	UPF0391 membrane protein
JM952_RS14940	COG1451	nucleotide metabolic process
JM952_RS14960	COG0183	Belongs to the thiolase family
JM952_RS14995	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JM952_RS14995	COG1793	dna ligase
JM952_RS15005	COG1793	dna ligase
JM952_RS15010	COG1201	RNA secondary structure unwinding
JM952_RS15020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_RS15025	COG1278	Cold shock
JM952_RS15030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JM952_RS15035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JM952_RS15045	COG3046	protein related to deoxyribodipyrimidine photolyase
JM952_RS15050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_RS15050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JM952_RS15055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JM952_RS15060	COG2954	triphosphatase activity
JM952_RS15110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JM952_RS15140	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JM952_RS15145	COG1024	Enoyl-CoA hydratase
JM952_RS15150	COG1960	acyl-CoA dehydrogenase activity
JM952_RS15160	COG1396	sequence-specific DNA binding
JM952_RS15160	COG3800	Transcriptional regulator
JM952_RS15170	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JM952_RS15175	COG3250	beta-galactosidase activity
JM952_RS15305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JM952_RS15360	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_RS15380	COG1309	transcriptional regulator
JM952_RS15385	COG0436	Aminotransferase
JM952_RS15395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JM952_RS15485	COG2003	Belongs to the UPF0758 family
JM952_RS15535	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
JM952_RS15540	COG0631	protein serine/threonine phosphatase activity
JM952_RS15545	COG4245	von Willebrand factor, type A
JM952_RS15600	COG0534	Mate efflux family protein
JM952_RS15630	COG2070	2-Nitropropane dioxygenase
JM952_RS15645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JM952_RS15650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JM952_RS15660	COG3534	alpha-L-arabinofuranosidase
JM952_RS15690	COG0784	Response regulator, receiver
JM952_RS15690	COG4191	Histidine kinase
JM952_RS15695	COG4999	Histidine kinase
JM952_RS15695	COG3850	Histidine kinase
JM952_RS15695	COG3437	response regulator, receiver
JM952_RS15695	COG2205	protein histidine kinase activity
JM952_RS15700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JM952_RS15710	COG2205	protein histidine kinase activity
JM952_RS15715	COG5507	3-demethylubiquinone-9 3-methyltransferase
JM952_RS15725	COG4771	TonB-dependent receptor
JM952_RS15750	COG2172	sigma factor antagonist activity
JM952_RS15755	COG1366	Belongs to the anti-sigma-factor antagonist family
JM952_RS15760	COG1366	Belongs to the anti-sigma-factor antagonist family
JM952_RS15765	COG1902	pentaerythritol trinitrate reductase activity
JM952_RS15775	COG0326	Molecular chaperone. Has ATPase activity
JM952_RS15780	COG2207	Transcriptional regulator
JM952_RS15795	COG3152	Membrane
JM952_RS15810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JM952_RS15815	COG1845	cytochrome c oxidase, subunit III
JM952_RS15820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JM952_RS15850	COG0196	riboflavin kinase activity
JM952_RS15880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JM952_RS15885	COG0824	Thioesterase
JM952_RS15890	COG1024	Enoyl-CoA hydratase
JM952_RS15895	COG1946	Acyl-CoA thioesterase
JM952_RS15910	COG1595	DNA-templated transcription, initiation
JM952_RS15970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JM952_RS15995	COG2197	response regulator
JM952_RS16000	COG4585	Histidine kinase
JM952_RS16015	COG2894	cell division
JM952_RS16030	COG5002	protein histidine kinase activity
JM952_RS16035	COG0745	RESPONSE REGULATOR receiver
JM952_RS16070	COG2814	Major facilitator Superfamily
JM952_RS16090	COG0656	L-ascorbic acid biosynthetic process
JM952_RS16095	COG0753	catalase activity
JM952_RS16110	COG2207	Transcriptional regulator
JM952_RS16110	COG1917	Cupin 2, conserved barrel domain protein
JM952_RS16130	COG0823	Involved in the tonB-independent uptake of proteins
JM952_RS16130	COG1506	peptidase
JM952_RS16140	COG1297	OPT oligopeptide transporter protein
JM952_RS16165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JM952_RS16195	COG2080	2 iron, 2 sulfur cluster binding
JM952_RS16200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JM952_RS16205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JM952_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS16255	COG3537	Alpha-1,2-mannosidase
JM952_RS16265	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS16270	COG3387	PFAM Glycoside hydrolase 15-related
JM952_RS16285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JM952_RS16320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JM952_RS16325	COG0732	type I restriction modification DNA specificity domain
JM952_RS16335	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JM952_RS16385	COG0308	aminopeptidase N
JM952_RS16400	COG0330	HflC and HflK could
JM952_RS16405	COG0330	HflC and HflK could
JM952_RS16425	COG0678	peroxiredoxin activity
JM952_RS16435	COG4953	penicillin-binding protein 1C
JM952_RS16460	COG2373	Large extracellular alpha-helical protein
JM952_RS16505	COG3829	transcription factor binding
JM952_RS16615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JM952_RS16620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JM952_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS16640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JM952_RS16645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_RS16655	COG1399	metal-binding, possibly nucleic acid-binding protein
JM952_RS16685	COG0714	Associated with various cellular activities
JM952_RS16705	COG0537	adenosine 5'-monophosphoramidase activity
JM952_RS16735	COG0314	molybdopterin synthase activity
JM952_RS16740	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JM952_RS16760	COG1234	tRNA 3'-trailer cleavage
JM952_RS16770	COG0859	PFAM glycosyl transferase family 9
JM952_RS16785	COG0631	protein serine/threonine phosphatase activity
JM952_RS16790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JM952_RS16815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JM952_RS16890	COG0473	3-isopropylmalate dehydrogenase activity
JM952_RS16905	COG4783	chaperone-mediated protein folding
JM952_RS16910	COG0745	RESPONSE REGULATOR receiver
JM952_RS16920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JM952_RS16930	COG0438	transferase activity, transferring glycosyl groups
JM952_RS16935	COG0671	phosphoesterase, PA-phosphatase related
JM952_RS16940	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JM952_RS16950	COG3291	Pkd domain containing protein
JM952_RS16955	COG2833	Protein of unknown function (DUF455)
JM952_RS16975	COG0285	dihydrofolate synthase activity
JM952_RS16990	COG0406	alpha-ribazole phosphatase activity
JM952_RS17015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JM952_RS17020	COG4208	sulfate ABC transporter
JM952_RS17025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JM952_RS17030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JM952_RS17065	COG1902	pentaerythritol trinitrate reductase activity
JM952_RS17065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JM952_RS17085	COG0625	glutathione transferase activity
JM952_RS17095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JM952_RS17100	COG1217	gtp-binding protein TYPA
JM952_RS17110	COG0154	amidase activity
JM952_RS17125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JM952_RS17160	COG0201	protein transport
JM952_RS17320	COG0250	Participates in transcription elongation, termination and antitermination
JM952_RS17355	COG0012	GTP binding
JM952_RS17360	COG0193	aminoacyl-tRNA hydrolase activity
JM952_RS17370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JM952_RS17410	COG0521	Mo-molybdopterin cofactor biosynthetic process
JM952_RS17430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_RS17460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JM952_RS17465	COG1404	Belongs to the peptidase S8 family
JM952_RS17475	COG1404	Belongs to the peptidase S8 family
JM952_RS17480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JM952_RS17545	COG0778	Nitroreductase
JM952_RS17550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM952_RS17550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM952_RS17570	COG2890	protein-(glutamine-N5) methyltransferase activity
JM952_RS17580	COG3634	alkyl hydroperoxide reductase activity
JM952_RS17585	COG0583	DNA-binding transcription factor activity
JM952_RS17590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_RS17615	COG2197	response regulator
JM952_RS17620	COG2205	protein histidine kinase activity
JM952_RS17620	COG5002	protein histidine kinase activity
JM952_RS17620	COG0784	Response regulator, receiver
JM952_RS17650	COG0697	spore germination
JM952_RS17680	COG3386	PFAM SMP-30 Gluconolaconase
JM952_RS17700	COG1024	Enoyl-CoA hydratase
JM952_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_RS17715	COG0583	DNA-binding transcription factor activity
JM952_RS17720	COG3384	dioxygenase
JM952_RS17750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_RS17755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_RS17765	COG2096	Adenosyltransferase
JM952_RS17770	COG0123	including yeast histone deacetylase and acetoin utilization protein
JM952_RS17805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JM952_RS17840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JM952_RS17850	COG0642	Histidine kinase
JM952_RS17865	COG4181	ATPase activity
JM952_RS17875	COG2175	clavaminate synthase activity
JM952_RS17910	COG4771	TonB-dependent receptor
JM952_RS17920	COG0667	Aldo Keto reductase
JM952_RS17925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JM952_RS17935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JM952_RS18030	COG0366	Alpha amylase catalytic
JM952_RS18065	COG0604	alcohol dehydrogenase
JM952_RS18065	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS18065	COG3321	synthase
JM952_RS18080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JM952_RS18095	COG0494	nUDIX hydrolase
JM952_RS18110	COG0739	heme binding
JM952_RS18135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JM952_RS18140	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM952_RS18165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JM952_RS18180	COG3116	cell division
JM952_RS18230	COG1988	membrane-bound metal-dependent
JM952_RS18235	COG0277	FAD linked oxidase domain protein
JM952_RS18245	COG0745	RESPONSE REGULATOR receiver
JM952_RS18250	COG2205	protein histidine kinase activity
JM952_RS18260	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JM952_RS18265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JM952_RS18280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JM952_RS18310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JM952_RS18310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JM952_RS18335	COG0488	(ABC) transporter
JM952_RS18340	COG0242	peptide deformylase activity
JM952_RS18345	COG1393	Belongs to the ArsC family
JM952_RS18410	COG2188	Transcriptional regulator
JM952_RS18425	COG1450	Type ii and iii secretion system protein
JM952_RS18440	COG3166	PFAM Fimbrial assembly family protein
JM952_RS18445	COG3156	type II secretion system protein K
JM952_RS18450	COG4795	General secretion pathway protein
JM952_RS18455	COG2165	general secretion pathway protein
JM952_RS18460	COG4970	Tfp pilus assembly protein FimT
JM952_RS18465	COG2165	general secretion pathway protein
JM952_RS18470	COG1459	type II secretion system
JM952_RS18475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JM952_RS18480	COG1404	Belongs to the peptidase S8 family
JM952_RS18495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JM952_RS18495	COG0047	phosphoribosylformylglycinamidine synthase activity
JM952_RS18500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JM952_RS18505	COG4974	Belongs to the 'phage' integrase family
JM952_RS18520	COG0795	lipopolysaccharide-transporting ATPase activity
JM952_RS18580	COG1183	phosphatidylcholine synthase activity
JM952_RS18605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JM952_RS18610	COG1127	ABC transporter
JM952_RS18615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JM952_RS18615	COG3218	ABC-type transport auxiliary lipoprotein component
JM952_RS18655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JM952_RS18685	COG2086	electron transfer activity
JM952_RS18695	COG0662	Cupin 2, conserved barrel domain protein
JM952_RS18695	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JM952_RS18700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JM952_RS18705	COG0463	Glycosyl transferase, family 2
JM952_RS18725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_RS18730	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JM952_RS18745	COG0438	transferase activity, transferring glycosyl groups
JM952_RS18770	COG0626	cystathionine gamma-synthase activity
JM952_RS18800	COG0625	glutathione transferase activity
JM952_RS18810	COG0513	Belongs to the DEAD box helicase family
JM952_RS18815	COG0720	synthase
JM952_RS18830	COG1956	GAF domain-containing protein
JM952_RS18860	COG0339	signal peptide processing
JM952_RS18865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JM952_RS18915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JM952_RS18925	COG1136	(ABC) transporter
JM952_RS18935	COG0577	efflux transmembrane transporter activity
JM952_RS18935	COG1136	(ABC) transporter
JM952_RS19025	COG0356	it plays a direct role in the translocation of protons across the membrane
JM952_RS19040	COG1228	amidohydrolase
JM952_RS19045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM952_RS19055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM952_RS19095	COG2011	ABC-type metal ion transport system permease component
JM952_RS19105	COG0697	spore germination
JM952_RS19135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JM952_RS19140	COG1187	pseudouridine synthase activity
JM952_RS19145	COG2813	Specifically methylates the guanine in position
JM952_RS19165	COG5002	protein histidine kinase activity
JM952_RS19245	COG0842	Transport permease protein
JM952_RS19250	COG1131	(ABC) transporter
JM952_RS19255	COG0025	NhaP-type Na H and K H
JM952_RS19260	COG3795	YCII-related domain
JM952_RS19265	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JM952_RS19270	COG1573	uracil-dna glycosylase
JM952_RS19280	COG3384	dioxygenase
JM952_RS19285	COG0583	DNA-binding transcription factor activity
JM952_RS19295	COG0667	Aldo Keto reductase
JM952_RS19305	COG3590	peptidase
JM952_RS19320	COG0531	amino acid
JM952_RS19335	COG2972	Histidine kinase
JM952_RS19355	COG1335	isochorismatase
JM952_RS19360	COG3685	Protein conserved in bacteria
JM952_RS19365	COG3685	Protein conserved in bacteria
JM952_RS19370	COG3546	catalase activity
JM952_RS19400	COG2204	response regulator
JM952_RS19410	COG1271	oxidase subunit
JM952_RS19415	COG1294	oxidase, subunit
JM952_RS19430	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS19455	COG1132	(ABC) transporter
JM952_RS19470	COG1063	alcohol dehydrogenase
JM952_RS19570	COG0251	oxidation-reduction process
JM952_RS19590	COG0667	Aldo Keto reductase
JM952_RS19595	COG0583	DNA-binding transcription factor activity
JM952_RS19615	COG2203	Gaf domain
JM952_RS19615	COG5001	Diguanylate cyclase
JM952_RS19615	COG4251	negative regulation of phosphorylation
JM952_RS19615	COG3706	GGDEF domain
JM952_RS19645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JM952_RS19655	COG1560	Kdo2-lipid A biosynthetic process
JM952_RS19665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JM952_RS19700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JM952_RS19700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JM952_RS19710	COG0242	peptide deformylase activity
JM952_RS19715	COG1652	LysM domain
JM952_RS19720	COG0758	DNA mediated transformation
JM952_RS19740	COG1754	DNA topoisomerase type I activity
JM952_RS19740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JM952_RS19760	COG2203	Gaf domain
JM952_RS19760	COG3706	GGDEF domain
JM952_RS19760	COG5001	Diguanylate cyclase
JM952_RS19760	COG4251	negative regulation of phosphorylation
JM952_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS19775	COG0616	signal peptide processing
JM952_RS19780	COG0534	Mate efflux family protein
JM952_RS19795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JM952_RS19800	COG0625	glutathione transferase activity
JM952_RS19815	COG1252	NADH dehydrogenase
JM952_RS19820	COG2860	membrane
JM952_RS19825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JM952_RS19835	COG2201	protein-glutamate methylesterase activity
JM952_RS19840	COG2177	Part of the ABC transporter FtsEX involved in
JM952_RS19845	COG2884	Cell division ATP-binding protein ftsE
JM952_RS19855	COG3118	belongs to the thioredoxin family
JM952_RS19860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JM952_RS19905	COG1473	amidohydrolase
JM952_RS19910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_RS19940	COG4941	Belongs to the sigma-70 factor family
JM952_RS19945	COG5383	Protein conserved in bacteria
JM952_RS19985	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JM952_RS19990	COG3409	Peptidoglycan-binding domain 1 protein
JM952_RS19990	COG3501	Rhs element vgr protein
JM952_RS20005	COG3023	N-Acetylmuramoyl-L-alanine amidase
JM952_RS20015	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_RS20025	COG0531	amino acid
JM952_RS20040	COG4682	membrane
JM952_RS20045	COG2133	pyrroloquinoline quinone binding
JM952_RS20055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JM952_RS20070	COG1610	YqeY-like protein
JM952_RS20075	COG1295	ribonuclease BN
JM952_RS20080	COG0358	DNA primase activity
JM952_RS20130	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JM952_RS20145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JM952_RS20195	COG0739	heme binding
JM952_RS20220	COG0708	Exodeoxyribonuclease III
JM952_RS20235	COG1192	Involved in chromosome partitioning
JM952_RS20240	COG1475	DNA binding
JM952_RS20260	COG0463	Glycosyl transferase, family 2
JM952_RS20285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JM952_RS20310	COG4221	oxidoreductase activity
JM952_RS20315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JM952_RS20315	COG2755	lipolytic protein G-D-S-L family
JM952_RS20330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JM952_RS20335	COG1166	arginine decarboxylase activity
JM952_RS20360	COG2960	long-chain fatty acid transporting porin activity
JM952_RS20365	COG0606	chelatase, subunit chli
JM952_RS20380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JM952_RS20415	COG1690	Belongs to the RtcB family
JM952_RS20460	COG1090	epimerase
JM952_RS20480	COG0642	Histidine kinase
JM952_RS20500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JM952_RS20525	COG1011	Hydrolase
JM952_RS20530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JM952_RS20550	COG2197	response regulator
JM952_RS20555	COG4585	Histidine kinase
JM952_RS20565	COG1136	(ABC) transporter
JM952_RS20590	COG0697	spore germination
JM952_RS20610	COG0180	Tryptophanyl-tRNA synthetase
JM952_RS20615	COG3237	CsbD-like
JM952_RS20690	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JM952_RS20690	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JM952_RS20730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JM952_RS20755	COG1199	ATP-dependent helicase activity
JM952_RS20820	COG0625	glutathione transferase activity
JM952_RS20860	COG4555	ABC transporter
JM952_RS20870	COG1476	TRANSCRIPTIONal
JM952_RS20885	COG1230	cation diffusion facilitator family transporter
JM952_RS20895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JM952_RS20900	COG1131	(ABC) transporter
JM952_RS20905	COG0842	Transport permease protein
JM952_RS20915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JM952_RS20930	COG1607	acyl-coa hydrolase
JM952_RS20945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM952_RS20950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM952_RS20960	COG0045	succinate-CoA ligase (ADP-forming) activity
JM952_RS20960	COG1042	CoA-binding domain protein
JM952_RS20960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JM952_RS20970	COG2239	Acts as a magnesium transporter
JM952_RS20985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JM952_RS20990	COG3387	PFAM Glycoside hydrolase 15-related
JM952_RS21005	COG3100	YcgL domain-containing protein
JM952_RS21010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JM952_RS21020	COG0463	Glycosyl transferase, family 2
JM952_RS21040	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS21085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JM952_RS21155	COG0210	DNA helicase
JM952_RS21165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS21170	COG0583	DNA-binding transcription factor activity
JM952_RS21175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JM952_RS21185	COG2159	amidohydrolase
JM952_RS21240	COG3540	Alkaline phosphatase
JM952_RS21250	COG2826	transposase and inactivated derivatives, IS30 family
JM952_RS21300	COG2091	lysine biosynthetic process via aminoadipic acid
JM952_RS21350	COG1940	carbohydrate kinase activity
JM952_RS21360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JM952_RS21375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JM952_RS21380	COG3162	membrane
JM952_RS21415	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_RS21430	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_RS21435	COG0179	Fumarylacetoacetate (FAA) hydrolase
JM952_RS21440	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_RS21445	COG3254	rhamnose metabolic process
JM952_RS21450	COG0738	Major facilitator superfamily
JM952_RS21455	COG1414	Transcriptional regulator
JM952_RS21475	COG0784	Response regulator, receiver
JM952_RS21475	COG2205	protein histidine kinase activity
JM952_RS21480	COG3459	Glycosyltransferase 36 associated
JM952_RS21485	COG2211	Major facilitator Superfamily
JM952_RS21490	COG3265	gluconokinase activity
JM952_RS21495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_RS21520	COG2911	Protein conserved in bacteria
JM952_RS21525	COG0729	surface antigen
JM952_RS21540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JM952_RS21545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JM952_RS21545	COG0519	Catalyzes the synthesis of GMP from XMP
JM952_RS21555	COG0805	protein transport
JM952_RS21575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JM952_RS21610	COG3661	Belongs to the glycosyl hydrolase 67 family
JM952_RS21620	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_RS21630	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_RS21635	COG0246	Mannitol dehydrogenase
JM952_RS21675	COG3386	PFAM SMP-30 Gluconolaconase
JM952_RS21690	COG3250	beta-galactosidase activity
JM952_RS21700	COG3693	PFAM glycoside hydrolase, family 10
JM952_RS21715	COG2211	Major facilitator Superfamily
JM952_RS21755	COG2937	Belongs to the GPAT DAPAT family
JM952_RS21790	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JM952_RS21810	COG0210	DNA helicase
JM952_RS21895	COG3135	benzoate transporter
JM952_RS21920	COG0676	glucose-6-phosphate 1-epimerase activity
JM952_RS21940	COG0730	response to heat
JM952_RS21970	COG0302	gtp cyclohydrolase
JM952_RS21985	COG1566	PFAM secretion protein HlyD family protein
JM952_RS21995	COG1289	transmembrane transporter activity
JM952_RS22000	COG0477	Major facilitator Superfamily
JM952_RS22015	COG4221	oxidoreductase activity
JM952_RS22020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_RS22095	COG0564	pseudouridine synthase activity
JM952_RS22110	COG1192	Involved in chromosome partitioning
JM952_RS22150	COG1074	ATP-dependent DNA helicase activity
JM952_RS22155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JM952_RS22190	COG1127	ABC transporter
JM952_RS22195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JM952_RS22200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JM952_RS22215	COG2853	Lipoprotein
JM952_RS22225	COG0386	Belongs to the glutathione peroxidase family
JM952_RS22235	COG1322	Protein conserved in bacteria
JM952_RS22245	COG0604	alcohol dehydrogenase
JM952_RS22250	COG0583	DNA-binding transcription factor activity
JM952_RS22265	COG0531	amino acid
JM952_RS22275	COG4206	TonB-dependent receptor
JM952_RS22285	COG3706	GGDEF domain
JM952_RS22290	COG3835	regulator
JM952_RS22295	COG1929	Belongs to the glycerate kinase type-1 family
JM952_RS22300	COG2271	Major facilitator Superfamily
JM952_RS22320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JM952_RS22325	COG0861	Integral membrane protein TerC family
JM952_RS22350	COG0584	glycerophosphoryl diester phosphodiesterase
JM952_RS22365	COG0671	phosphoesterase, PA-phosphatase related
JM952_RS22380	COG0726	polysaccharide deacetylase
JM952_RS22385	COG0706	membrane insertase activity