locus-tag	class	description
XCCCN02v2_RS00020	COG0187	DNA topoisomerase II activity
XCCCN02v2_RS00030	COG0501	Belongs to the peptidase M48B family
XCCCN02v2_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN02v2_RS00105	COG0793	Belongs to the peptidase S41A family
XCCCN02v2_RS00110	COG4942	peptidase
XCCCN02v2_RS00120	COG2234	aminopeptidase activity
XCCCN02v2_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN02v2_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN02v2_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN02v2_RS00150	COG1064	alcohol dehydrogenase
XCCCN02v2_RS00160	COG0493	'glutamate synthase
XCCCN02v2_RS00165	COG0067	glutamate synthase
XCCCN02v2_RS00165	COG0069	glutamate synthase activity
XCCCN02v2_RS00165	COG0070	glutamate synthase
XCCCN02v2_RS00180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCCCN02v2_RS00190	COG1741	Belongs to the pirin family
XCCCN02v2_RS00200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCCCN02v2_RS00220	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS00280	COG1205	dead DEAH box helicase
XCCCN02v2_RS00280	COG1111	helicase
XCCCN02v2_RS00285	COG3177	Filamentation induced by cAMP protein fic
XCCCN02v2_RS00290	COG1272	protein, Hemolysin III
XCCCN02v2_RS00360	COG3237	CsbD-like
XCCCN02v2_RS00405	COG0628	permease
XCCCN02v2_RS00410	COG0657	acetylesterase activity
XCCCN02v2_RS00420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN02v2_RS00425	COG0477	Major facilitator Superfamily
XCCCN02v2_RS00465	COG0714	Associated with various cellular activities
XCCCN02v2_RS00505	COG4772	TonB-dependent receptor
XCCCN02v2_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN02v2_RS00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCCCN02v2_RS00560	COG4585	Histidine kinase
XCCCN02v2_RS00565	COG2197	response regulator
XCCCN02v2_RS00595	COG3710	Transcriptional regulator
XCCCN02v2_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN02v2_RS00645	COG4916	TIR domain
XCCCN02v2_RS00655	COG1192	Involved in chromosome partitioning
XCCCN02v2_RS00700	COG3039	Transposase
XCCCN02v2_RS00710	COG0366	Alpha amylase catalytic
XCCCN02v2_RS00715	COG0366	Alpha amylase catalytic
XCCCN02v2_RS00755	COG2755	lipolytic protein G-D-S-L family
XCCCN02v2_RS00765	COG0657	acetylesterase activity
XCCCN02v2_RS00765	COG2755	lipolytic protein G-D-S-L family
XCCCN02v2_RS00775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCCCN02v2_RS00790	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN02v2_RS00795	COG1609	Transcriptional regulator
XCCCN02v2_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS00815	COG2755	lipolytic protein G-D-S-L family
XCCCN02v2_RS00825	COG3186	Phenylalanine-4-hydroxylase
XCCCN02v2_RS00830	COG1522	sequence-specific DNA binding
XCCCN02v2_RS00845	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCCCN02v2_RS00855	COG1119	ATPase activity
XCCCN02v2_RS00870	COG0517	IMP dehydrogenase activity
XCCCN02v2_RS00870	COG1125	glycine betaine transport
XCCCN02v2_RS00885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN02v2_RS00890	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCCCN02v2_RS00920	COG0489	protein tyrosine kinase activity
XCCCN02v2_RS00925	COG0588	phosphoglycerate mutase activity
XCCCN02v2_RS00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS00960	COG1881	PFAM PEBP family protein
XCCCN02v2_RS00975	COG0174	glutamine synthetase
XCCCN02v2_RS00980	COG0347	Belongs to the P(II) protein family
XCCCN02v2_RS00985	COG0004	ammonium transporteR
XCCCN02v2_RS00990	COG3852	Histidine kinase
XCCCN02v2_RS00995	COG2204	response regulator
XCCCN02v2_RS01005	COG2032	superoxide dismutase activity
XCCCN02v2_RS01010	COG2032	superoxide dismutase activity
XCCCN02v2_RS01015	COG0346	lactoylglutathione lyase activity
XCCCN02v2_RS01025	COG0183	Belongs to the thiolase family
XCCCN02v2_RS01065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCCCN02v2_RS01085	COG0028	Belongs to the TPP enzyme family
XCCCN02v2_RS01100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCCCN02v2_RS01115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN02v2_RS01120	COG3177	Filamentation induced by cAMP protein fic
XCCCN02v2_RS01125	COG0596	Alpha beta hydrolase
XCCCN02v2_RS01130	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCCCN02v2_RS01135	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN02v2_RS01140	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN02v2_RS01185	COG2826	transposase and inactivated derivatives, IS30 family
XCCCN02v2_RS01195	COG3540	Alkaline phosphatase
XCCCN02v2_RS01250	COG2159	amidohydrolase
XCCCN02v2_RS01260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCCCN02v2_RS01265	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS01270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS01280	COG0210	DNA helicase
XCCCN02v2_RS01350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCCCN02v2_RS01395	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS01410	COG0463	Glycosyl transferase, family 2
XCCCN02v2_RS01420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCCCN02v2_RS01440	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN02v2_RS01445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN02v2_RS01460	COG2239	Acts as a magnesium transporter
XCCCN02v2_RS01470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCCCN02v2_RS01470	COG1042	CoA-binding domain protein
XCCCN02v2_RS01470	COG0045	succinate-CoA ligase (ADP-forming) activity
XCCCN02v2_RS01480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN02v2_RS01485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN02v2_RS01490	COG0716	FMN binding
XCCCN02v2_RS01500	COG1607	acyl-coa hydrolase
XCCCN02v2_RS01515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCCCN02v2_RS01525	COG0842	Transport permease protein
XCCCN02v2_RS01530	COG1131	(ABC) transporter
XCCCN02v2_RS01535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN02v2_RS01545	COG1230	cation diffusion facilitator family transporter
XCCCN02v2_RS01560	COG1476	TRANSCRIPTIONal
XCCCN02v2_RS01570	COG4555	ABC transporter
XCCCN02v2_RS01610	COG0625	glutathione transferase activity
XCCCN02v2_RS01675	COG1199	ATP-dependent helicase activity
XCCCN02v2_RS01705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN02v2_RS01745	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCCCN02v2_RS01745	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCCCN02v2_RS01820	COG3237	CsbD-like
XCCCN02v2_RS01825	COG0180	Tryptophanyl-tRNA synthetase
XCCCN02v2_RS01850	COG0697	spore germination
XCCCN02v2_RS01875	COG1136	(ABC) transporter
XCCCN02v2_RS01890	COG4585	Histidine kinase
XCCCN02v2_RS01895	COG2197	response regulator
XCCCN02v2_RS01915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCCCN02v2_RS01920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN02v2_RS01945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN02v2_RS01965	COG0642	Histidine kinase
XCCCN02v2_RS01980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN02v2_RS01985	COG1090	epimerase
XCCCN02v2_RS02030	COG1690	Belongs to the RtcB family
XCCCN02v2_RS02075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCCCN02v2_RS02090	COG0606	chelatase, subunit chli
XCCCN02v2_RS02095	COG2960	long-chain fatty acid transporting porin activity
XCCCN02v2_RS02120	COG1166	arginine decarboxylase activity
XCCCN02v2_RS02140	COG2755	lipolytic protein G-D-S-L family
XCCCN02v2_RS02140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCCCN02v2_RS02145	COG4221	oxidoreductase activity
XCCCN02v2_RS02170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCCCN02v2_RS02195	COG0463	Glycosyl transferase, family 2
XCCCN02v2_RS02215	COG1475	DNA binding
XCCCN02v2_RS02220	COG1192	Involved in chromosome partitioning
XCCCN02v2_RS02235	COG0708	Exodeoxyribonuclease III
XCCCN02v2_RS02245	COG2223	nitrite transmembrane transporter activity
XCCCN02v2_RS02260	COG0739	heme binding
XCCCN02v2_RS02305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCCCN02v2_RS02320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCCCN02v2_RS02370	COG0358	DNA primase activity
XCCCN02v2_RS02375	COG1295	ribonuclease BN
XCCCN02v2_RS02380	COG1610	YqeY-like protein
XCCCN02v2_RS02395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCCCN02v2_RS02405	COG2133	pyrroloquinoline quinone binding
XCCCN02v2_RS02410	COG4682	membrane
XCCCN02v2_RS02425	COG0531	amino acid
XCCCN02v2_RS02435	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN02v2_RS02445	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCCCN02v2_RS02460	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN02v2_RS02460	COG3501	Rhs element vgr protein
XCCCN02v2_RS02465	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCCCN02v2_RS02505	COG5383	Protein conserved in bacteria
XCCCN02v2_RS02510	COG4941	Belongs to the sigma-70 factor family
XCCCN02v2_RS02540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN02v2_RS02545	COG1473	amidohydrolase
XCCCN02v2_RS02590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCCCN02v2_RS02595	COG3118	belongs to the thioredoxin family
XCCCN02v2_RS02605	COG2884	Cell division ATP-binding protein ftsE
XCCCN02v2_RS02610	COG2177	Part of the ABC transporter FtsEX involved in
XCCCN02v2_RS02615	COG2201	protein-glutamate methylesterase activity
XCCCN02v2_RS02625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN02v2_RS02630	COG2860	membrane
XCCCN02v2_RS02635	COG1252	NADH dehydrogenase
XCCCN02v2_RS02655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCCCN02v2_RS02670	COG0534	Mate efflux family protein
XCCCN02v2_RS02675	COG0616	signal peptide processing
XCCCN02v2_RS02685	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS02690	COG5001	Diguanylate cyclase
XCCCN02v2_RS02690	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS02690	COG3706	GGDEF domain
XCCCN02v2_RS02690	COG2203	Gaf domain
XCCCN02v2_RS02710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN02v2_RS02710	COG1754	DNA topoisomerase type I activity
XCCCN02v2_RS02730	COG0758	DNA mediated transformation
XCCCN02v2_RS02735	COG1652	LysM domain
XCCCN02v2_RS02740	COG0242	peptide deformylase activity
XCCCN02v2_RS02750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCCCN02v2_RS02750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCCCN02v2_RS02785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCCCN02v2_RS02795	COG1560	Kdo2-lipid A biosynthetic process
XCCCN02v2_RS02805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN02v2_RS02835	COG5001	Diguanylate cyclase
XCCCN02v2_RS02835	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS02835	COG3706	GGDEF domain
XCCCN02v2_RS02835	COG2203	Gaf domain
XCCCN02v2_RS02855	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS02860	COG0667	Aldo Keto reductase
XCCCN02v2_RS02880	COG0251	oxidation-reduction process
XCCCN02v2_RS02940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN02v2_RS02980	COG1063	alcohol dehydrogenase
XCCCN02v2_RS02995	COG1132	(ABC) transporter
XCCCN02v2_RS03015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCCCN02v2_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS03035	COG1294	oxidase, subunit
XCCCN02v2_RS03040	COG1271	oxidase subunit
XCCCN02v2_RS03050	COG2204	response regulator
XCCCN02v2_RS03080	COG3546	catalase activity
XCCCN02v2_RS03085	COG3685	Protein conserved in bacteria
XCCCN02v2_RS03090	COG3685	Protein conserved in bacteria
XCCCN02v2_RS03095	COG1335	isochorismatase
XCCCN02v2_RS03120	COG2972	Histidine kinase
XCCCN02v2_RS03135	COG0531	amino acid
XCCCN02v2_RS03150	COG3590	peptidase
XCCCN02v2_RS03160	COG0667	Aldo Keto reductase
XCCCN02v2_RS03170	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS03175	COG3384	dioxygenase
XCCCN02v2_RS03185	COG1573	uracil-dna glycosylase
XCCCN02v2_RS03190	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCCCN02v2_RS03195	COG3795	YCII-related domain
XCCCN02v2_RS03200	COG0025	NhaP-type Na H and K H
XCCCN02v2_RS03205	COG1131	(ABC) transporter
XCCCN02v2_RS03210	COG0842	Transport permease protein
XCCCN02v2_RS03290	COG5002	protein histidine kinase activity
XCCCN02v2_RS03310	COG2813	Specifically methylates the guanine in position
XCCCN02v2_RS03315	COG1187	pseudouridine synthase activity
XCCCN02v2_RS03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN02v2_RS03350	COG0697	spore germination
XCCCN02v2_RS03360	COG2011	ABC-type metal ion transport system permease component
XCCCN02v2_RS03390	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN02v2_RS03400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN02v2_RS03405	COG1228	amidohydrolase
XCCCN02v2_RS03420	COG0356	it plays a direct role in the translocation of protons across the membrane
XCCCN02v2_RS03485	COG4191	Histidine kinase
XCCCN02v2_RS03505	COG0577	efflux transmembrane transporter activity
XCCCN02v2_RS03510	COG1136	(ABC) transporter
XCCCN02v2_RS03575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCCCN02v2_RS03580	COG0339	signal peptide processing
XCCCN02v2_RS03610	COG1956	GAF domain-containing protein
XCCCN02v2_RS03625	COG0720	synthase
XCCCN02v2_RS03630	COG0513	Belongs to the DEAD box helicase family
XCCCN02v2_RS03640	COG0625	glutathione transferase activity
XCCCN02v2_RS03670	COG0626	cystathionine gamma-synthase activity
XCCCN02v2_RS03695	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS03710	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCCCN02v2_RS03735	COG0463	Glycosyl transferase, family 2
XCCCN02v2_RS03750	COG2086	electron transfer activity
XCCCN02v2_RS03775	COG0662	Cupin 2, conserved barrel domain protein
XCCCN02v2_RS03775	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN02v2_RS03780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCCCN02v2_RS03820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN02v2_RS03820	COG3218	ABC-type transport auxiliary lipoprotein component
XCCCN02v2_RS03825	COG1127	ABC transporter
XCCCN02v2_RS03830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN02v2_RS03855	COG1183	phosphatidylcholine synthase activity
XCCCN02v2_RS03925	COG0795	lipopolysaccharide-transporting ATPase activity
XCCCN02v2_RS03940	COG4974	Belongs to the 'phage' integrase family
XCCCN02v2_RS03945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN02v2_RS03950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCCCN02v2_RS03950	COG0047	phosphoribosylformylglycinamidine synthase activity
XCCCN02v2_RS03965	COG1404	Belongs to the peptidase S8 family
XCCCN02v2_RS03970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN02v2_RS03975	COG1459	type II secretion system
XCCCN02v2_RS03980	COG2165	general secretion pathway protein
XCCCN02v2_RS03985	COG4970	Tfp pilus assembly protein FimT
XCCCN02v2_RS03990	COG2165	general secretion pathway protein
XCCCN02v2_RS03995	COG4795	General secretion pathway protein
XCCCN02v2_RS04000	COG3156	type II secretion system protein K
XCCCN02v2_RS04005	COG3166	PFAM Fimbrial assembly family protein
XCCCN02v2_RS04020	COG1450	Type ii and iii secretion system protein
XCCCN02v2_RS04035	COG2188	Transcriptional regulator
XCCCN02v2_RS04105	COG1393	Belongs to the ArsC family
XCCCN02v2_RS04110	COG0242	peptide deformylase activity
XCCCN02v2_RS04115	COG0488	(ABC) transporter
XCCCN02v2_RS04140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN02v2_RS04140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN02v2_RS04170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCCCN02v2_RS04185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCCCN02v2_RS04190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCCCN02v2_RS04200	COG2205	protein histidine kinase activity
XCCCN02v2_RS04205	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS04215	COG0277	FAD linked oxidase domain protein
XCCCN02v2_RS04220	COG1988	membrane-bound metal-dependent
XCCCN02v2_RS04280	COG3116	cell division
XCCCN02v2_RS04295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCCCN02v2_RS04320	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN02v2_RS04325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCCCN02v2_RS04350	COG0739	heme binding
XCCCN02v2_RS04365	COG0494	nUDIX hydrolase
XCCCN02v2_RS04380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN02v2_RS04395	COG0604	alcohol dehydrogenase
XCCCN02v2_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS04395	COG3321	synthase
XCCCN02v2_RS04430	COG0366	Alpha amylase catalytic
XCCCN02v2_RS04525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN02v2_RS04535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCCCN02v2_RS04540	COG0667	Aldo Keto reductase
XCCCN02v2_RS04550	COG4771	TonB-dependent receptor
XCCCN02v2_RS04575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCCCN02v2_RS04585	COG2175	clavaminate synthase activity
XCCCN02v2_RS04595	COG4181	ATPase activity
XCCCN02v2_RS04610	COG0642	Histidine kinase
XCCCN02v2_RS04620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCCCN02v2_RS04655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCCCN02v2_RS04685	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCCCN02v2_RS04690	COG2096	Adenosyltransferase
XCCCN02v2_RS04700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN02v2_RS04705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN02v2_RS04735	COG3384	dioxygenase
XCCCN02v2_RS04740	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS04745	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN02v2_RS04755	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS04775	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN02v2_RS04805	COG0697	spore germination
XCCCN02v2_RS04835	COG0784	Response regulator, receiver
XCCCN02v2_RS04835	COG2205	protein histidine kinase activity
XCCCN02v2_RS04835	COG5002	protein histidine kinase activity
XCCCN02v2_RS04840	COG2197	response regulator
XCCCN02v2_RS04865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN02v2_RS04870	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS04875	COG3634	alkyl hydroperoxide reductase activity
XCCCN02v2_RS04885	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN02v2_RS04910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN02v2_RS04910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN02v2_RS04915	COG0778	Nitroreductase
XCCCN02v2_RS04980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCCCN02v2_RS04985	COG1404	Belongs to the peptidase S8 family
XCCCN02v2_RS04990	COG1404	Belongs to the peptidase S8 family
XCCCN02v2_RS04995	COG1404	Belongs to the peptidase S8 family
XCCCN02v2_RS05000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCCCN02v2_RS05030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN02v2_RS05050	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCCCN02v2_RS05090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCCCN02v2_RS05100	COG0193	aminoacyl-tRNA hydrolase activity
XCCCN02v2_RS05105	COG0012	GTP binding
XCCCN02v2_RS05135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XCCCN02v2_RS05140	COG0250	Participates in transcription elongation, termination and antitermination
XCCCN02v2_RS05145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCCCN02v2_RS05215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCCCN02v2_RS05300	COG0201	protein transport
XCCCN02v2_RS05335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCCCN02v2_RS05345	COG0154	amidase activity
XCCCN02v2_RS05355	COG1217	gtp-binding protein TYPA
XCCCN02v2_RS05360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCCCN02v2_RS05370	COG0625	glutathione transferase activity
XCCCN02v2_RS05390	COG1902	pentaerythritol trinitrate reductase activity
XCCCN02v2_RS05390	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCCCN02v2_RS05425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCCCN02v2_RS05430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCCCN02v2_RS05435	COG4208	sulfate ABC transporter
XCCCN02v2_RS05440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCCCN02v2_RS05465	COG0406	alpha-ribazole phosphatase activity
XCCCN02v2_RS05480	COG0285	dihydrofolate synthase activity
XCCCN02v2_RS05500	COG2833	Protein of unknown function (DUF455)
XCCCN02v2_RS05505	COG3291	Pkd domain containing protein
XCCCN02v2_RS05515	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCCCN02v2_RS05520	COG0671	phosphoesterase, PA-phosphatase related
XCCCN02v2_RS05525	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS05535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCCCN02v2_RS05545	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS05550	COG4783	chaperone-mediated protein folding
XCCCN02v2_RS05565	COG0473	3-isopropylmalate dehydrogenase activity
XCCCN02v2_RS05665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCCCN02v2_RS05670	COG0631	protein serine/threonine phosphatase activity
XCCCN02v2_RS05685	COG0859	PFAM glycosyl transferase family 9
XCCCN02v2_RS05695	COG1234	tRNA 3'-trailer cleavage
XCCCN02v2_RS05715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCCCN02v2_RS05720	COG0314	molybdopterin synthase activity
XCCCN02v2_RS05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XCCCN02v2_RS05760	COG4191	Histidine kinase
XCCCN02v2_RS05800	COG2003	Belongs to the UPF0758 family
XCCCN02v2_RS05865	COG0537	adenosine 5'-monophosphoramidase activity
XCCCN02v2_RS05885	COG0714	Associated with various cellular activities
XCCCN02v2_RS05915	COG1399	metal-binding, possibly nucleic acid-binding protein
XCCCN02v2_RS05925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN02v2_RS05930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCCCN02v2_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS05950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCCCN02v2_RS05955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCCCN02v2_RS06065	COG3829	transcription factor binding
XCCCN02v2_RS06085	COG3609	addiction module antidote protein, CC2985 family
XCCCN02v2_RS06115	COG2373	Large extracellular alpha-helical protein
XCCCN02v2_RS06140	COG4953	penicillin-binding protein 1C
XCCCN02v2_RS06150	COG0678	peroxiredoxin activity
XCCCN02v2_RS06170	COG0330	HflC and HflK could
XCCCN02v2_RS06175	COG0330	HflC and HflK could
XCCCN02v2_RS06190	COG0308	aminopeptidase N
XCCCN02v2_RS06240	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XCCCN02v2_RS06255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN02v2_RS06290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN02v2_RS06305	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN02v2_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS06320	COG3537	Alpha-1,2-mannosidase
XCCCN02v2_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS06370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN02v2_RS06375	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN02v2_RS06380	COG2080	2 iron, 2 sulfur cluster binding
XCCCN02v2_RS06405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN02v2_RS06430	COG1297	OPT oligopeptide transporter protein
XCCCN02v2_RS06440	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN02v2_RS06440	COG1506	peptidase
XCCCN02v2_RS06460	COG2207	Transcriptional regulator
XCCCN02v2_RS06460	COG1917	Cupin 2, conserved barrel domain protein
XCCCN02v2_RS06475	COG0753	catalase activity
XCCCN02v2_RS06480	COG0656	L-ascorbic acid biosynthetic process
XCCCN02v2_RS06500	COG2814	Major facilitator Superfamily
XCCCN02v2_RS06520	COG2194	sulfuric ester hydrolase activity
XCCCN02v2_RS06535	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS06540	COG5002	protein histidine kinase activity
XCCCN02v2_RS06555	COG2894	cell division
XCCCN02v2_RS06575	COG2197	response regulator
XCCCN02v2_RS06600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN02v2_RS06675	COG1946	Acyl-CoA thioesterase
XCCCN02v2_RS06680	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS06685	COG0824	Thioesterase
XCCCN02v2_RS06690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCCCN02v2_RS06720	COG0196	riboflavin kinase activity
XCCCN02v2_RS06750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCCCN02v2_RS06755	COG1845	cytochrome c oxidase, subunit III
XCCCN02v2_RS06760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCCCN02v2_RS06775	COG3152	Membrane
XCCCN02v2_RS06790	COG2207	Transcriptional regulator
XCCCN02v2_RS06795	COG0326	Molecular chaperone. Has ATPase activity
XCCCN02v2_RS06805	COG1902	pentaerythritol trinitrate reductase activity
XCCCN02v2_RS06810	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN02v2_RS06815	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN02v2_RS06820	COG2172	sigma factor antagonist activity
XCCCN02v2_RS06845	COG4771	TonB-dependent receptor
XCCCN02v2_RS06855	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCCCN02v2_RS06860	COG2205	protein histidine kinase activity
XCCCN02v2_RS06870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN02v2_RS06875	COG3437	response regulator, receiver
XCCCN02v2_RS06875	COG2205	protein histidine kinase activity
XCCCN02v2_RS06875	COG4999	Histidine kinase
XCCCN02v2_RS06875	COG3850	Histidine kinase
XCCCN02v2_RS06880	COG0784	Response regulator, receiver
XCCCN02v2_RS06880	COG4191	Histidine kinase
XCCCN02v2_RS06910	COG3534	alpha-L-arabinofuranosidase
XCCCN02v2_RS06920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN02v2_RS06925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCCCN02v2_RS06940	COG2070	2-Nitropropane dioxygenase
XCCCN02v2_RS06970	COG0534	Mate efflux family protein
XCCCN02v2_RS06990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCCCN02v2_RS07000	COG3483	tryptophan 2,3-dioxygenase activity
XCCCN02v2_RS07015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN02v2_RS07025	COG0436	Aminotransferase
XCCCN02v2_RS07030	COG1309	transcriptional regulator
XCCCN02v2_RS07050	COG3039	Transposase
XCCCN02v2_RS07080	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN02v2_RS07135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCCCN02v2_RS07260	COG3250	beta-galactosidase activity
XCCCN02v2_RS07265	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCCCN02v2_RS07275	COG1396	sequence-specific DNA binding
XCCCN02v2_RS07275	COG3800	Transcriptional regulator
XCCCN02v2_RS07285	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS07290	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS07325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN02v2_RS07375	COG2954	triphosphatase activity
XCCCN02v2_RS07380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCCCN02v2_RS07385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCCCN02v2_RS07385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN02v2_RS07390	COG3046	protein related to deoxyribodipyrimidine photolyase
XCCCN02v2_RS07400	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCCCN02v2_RS07405	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCCCN02v2_RS07410	COG1278	Cold shock
XCCCN02v2_RS07415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN02v2_RS07425	COG1201	RNA secondary structure unwinding
XCCCN02v2_RS07430	COG1793	dna ligase
XCCCN02v2_RS07440	COG1793	dna ligase
XCCCN02v2_RS07440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCCCN02v2_RS07475	COG0183	Belongs to the thiolase family
XCCCN02v2_RS07495	COG1451	nucleotide metabolic process
XCCCN02v2_RS07500	COG5487	UPF0391 membrane protein
XCCCN02v2_RS07510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCCCN02v2_RS07560	COG1047	Peptidyl-prolyl cis-trans
XCCCN02v2_RS07570	COG2824	Alkylphosphonate utilization operon protein PhnA
XCCCN02v2_RS07590	COG1902	pentaerythritol trinitrate reductase activity
XCCCN02v2_RS07595	COG2814	Major facilitator Superfamily
XCCCN02v2_RS07630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCCCN02v2_RS07630	COG0392	lysyltransferase activity
XCCCN02v2_RS07640	COG0251	oxidation-reduction process
XCCCN02v2_RS07645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN02v2_RS07660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN02v2_RS07685	COG1595	DNA-templated transcription, initiation
XCCCN02v2_RS07700	COG2878	Part of a membrane complex involved in electron transport
XCCCN02v2_RS07725	COG0346	lactoylglutathione lyase activity
XCCCN02v2_RS07730	COG0833	amino acid
XCCCN02v2_RS07735	COG2040	homocysteine
XCCCN02v2_RS07745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN02v2_RS07775	COG1695	Transcriptional regulator
XCCCN02v2_RS07800	COG1981	membrane
XCCCN02v2_RS07855	COG0750	zinc metalloprotease
XCCCN02v2_RS07865	COG0575	Belongs to the CDS family
XCCCN02v2_RS07870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCCCN02v2_RS07880	COG0528	UMP kinase activity
XCCCN02v2_RS07950	COG1393	Belongs to the ArsC family
XCCCN02v2_RS07965	COG0367	asparagine synthase
XCCCN02v2_RS07975	COG4774	siderophore transport
XCCCN02v2_RS08015	COG1566	PFAM secretion protein HlyD family protein
XCCCN02v2_RS08020	COG2814	Major facilitator Superfamily
XCCCN02v2_RS08050	COG3104	oligopeptide transport
XCCCN02v2_RS08085	COG0339	signal peptide processing
XCCCN02v2_RS08090	COG0386	Belongs to the glutathione peroxidase family
XCCCN02v2_RS08150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCCCN02v2_RS08155	COG0084	hydrolase, TatD family'
XCCCN02v2_RS08170	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08185	COG0367	asparagine synthase
XCCCN02v2_RS08195	COG0305	Participates in initiation and elongation during chromosome replication
XCCCN02v2_RS08200	COG0415	Belongs to the DNA photolyase family
XCCCN02v2_RS08210	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS08220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN02v2_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS08250	COG3706	GGDEF domain
XCCCN02v2_RS08290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN02v2_RS08300	COG0497	DNA recombination
XCCCN02v2_RS08305	COG1420	regulation of RNA biosynthetic process
XCCCN02v2_RS08310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCCCN02v2_RS08330	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCCCN02v2_RS08355	COG2274	protein secretion by the type I secretion system
XCCCN02v2_RS08360	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS08365	COG1132	(ABC) transporter
XCCCN02v2_RS08400	COG2850	peptidyl-arginine hydroxylation
XCCCN02v2_RS08420	COG1253	flavin adenine dinucleotide binding
XCCCN02v2_RS08450	COG1131	(ABC) transporter
XCCCN02v2_RS08455	COG1725	Transcriptional regulator
XCCCN02v2_RS08465	COG0386	Belongs to the glutathione peroxidase family
XCCCN02v2_RS08505	COG1609	Transcriptional regulator
XCCCN02v2_RS08515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN02v2_RS08525	COG0646	methionine synthase
XCCCN02v2_RS08525	COG1410	methionine synthase
XCCCN02v2_RS08530	COG1410	methionine synthase
XCCCN02v2_RS08530	COG0646	methionine synthase
XCCCN02v2_RS08535	COG2226	methyltransferase
XCCCN02v2_RS08540	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08545	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08550	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08555	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08560	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08565	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08570	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08575	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS08590	COG0557	exoribonuclease II activity
XCCCN02v2_RS08605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN02v2_RS08625	COG0704	Plays a role in the regulation of phosphate uptake
XCCCN02v2_RS08635	COG0581	inorganic phosphate transmembrane transporter activity
XCCCN02v2_RS08640	COG0573	inorganic phosphate transmembrane transporter activity
XCCCN02v2_RS08645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCCCN02v2_RS08670	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN02v2_RS08675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCCCN02v2_RS08685	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS08695	COG0494	nUDIX hydrolase
XCCCN02v2_RS08730	COG2264	protein methyltransferase activity
XCCCN02v2_RS08735	COG0488	(ABC) transporter
XCCCN02v2_RS08755	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCCCN02v2_RS08770	COG2925	Exonuclease
XCCCN02v2_RS08795	COG0288	reversible hydration of carbon dioxide
XCCCN02v2_RS08820	COG0017	Asparaginyl-tRNA synthetase
XCCCN02v2_RS08825	COG0316	Belongs to the HesB IscA family
XCCCN02v2_RS08870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCCCN02v2_RS08890	COG4993	Dehydrogenase
XCCCN02v2_RS08900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCCCN02v2_RS08955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCCCN02v2_RS08965	COG1605	Chorismate mutase
XCCCN02v2_RS08965	COG0077	Prephenate dehydratase
XCCCN02v2_RS08975	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCCCN02v2_RS08990	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS09065	COG2003	Belongs to the UPF0758 family
XCCCN02v2_RS09115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCCCN02v2_RS09175	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCCCN02v2_RS09180	COG0784	Response regulator, receiver
XCCCN02v2_RS09180	COG4191	Histidine kinase
XCCCN02v2_RS09195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN02v2_RS09215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN02v2_RS09250	COG3038	cytochrome b561
XCCCN02v2_RS09265	COG2244	polysaccharide biosynthetic process
XCCCN02v2_RS09295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN02v2_RS09300	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS09305	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS09330	COG0477	Major facilitator Superfamily
XCCCN02v2_RS09335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCCCN02v2_RS09350	COG1253	flavin adenine dinucleotide binding
XCCCN02v2_RS09375	COG2134	cdp-diacylglycerol pyrophosphatase
XCCCN02v2_RS09435	COG2840	Smr protein MutS2
XCCCN02v2_RS09450	COG1238	metal cluster binding
XCCCN02v2_RS09465	COG1534	Rna-binding protein
XCCCN02v2_RS09475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCCCN02v2_RS09480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCCCN02v2_RS09495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCCCN02v2_RS09500	COG1546	Belongs to the CinA family
XCCCN02v2_RS09510	COG4771	TonB-dependent receptor
XCCCN02v2_RS09520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN02v2_RS09555	COG1741	Belongs to the pirin family
XCCCN02v2_RS09560	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS09585	COG0352	thiamine-phosphate diphosphorylase activity
XCCCN02v2_RS09585	COG0351	phosphomethylpyrimidine kinase
XCCCN02v2_RS09595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCCCN02v2_RS09600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCCCN02v2_RS09615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN02v2_RS09625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCCCN02v2_RS09630	COG3734	2-keto-3-deoxy-galactonokinase
XCCCN02v2_RS09645	COG0800	Aldolase
XCCCN02v2_RS09685	COG1501	Belongs to the glycosyl hydrolase 31 family
XCCCN02v2_RS09695	COG1070	Carbohydrate kinase
XCCCN02v2_RS09705	COG0477	Major facilitator Superfamily
XCCCN02v2_RS09725	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN02v2_RS09780	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN02v2_RS09790	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS09790	COG3706	GGDEF domain
XCCCN02v2_RS09790	COG2203	Gaf domain
XCCCN02v2_RS09790	COG5001	Diguanylate cyclase
XCCCN02v2_RS09795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN02v2_RS09800	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCCCN02v2_RS09815	COG0671	phosphoesterase, PA-phosphatase related
XCCCN02v2_RS09825	COG1794	racemase activity, acting on amino acids and derivatives
XCCCN02v2_RS09830	COG0697	spore germination
XCCCN02v2_RS09855	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN02v2_RS09920	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCCCN02v2_RS09940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCCCN02v2_RS09950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN02v2_RS09980	COG0131	Imidazoleglycerol-phosphate dehydratase
XCCCN02v2_RS09980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCCCN02v2_RS10000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCCCN02v2_RS10000	COG0140	phosphoribosyl-ATP diphosphatase activity
XCCCN02v2_RS10030	COG0531	amino acid
XCCCN02v2_RS10035	COG0531	amino acid
XCCCN02v2_RS10050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN02v2_RS10055	COG0277	FAD linked oxidase domain protein
XCCCN02v2_RS10090	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN02v2_RS10120	COG2258	MOSC domain
XCCCN02v2_RS10130	COG0505	Belongs to the CarA family
XCCCN02v2_RS10140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCCCN02v2_RS10145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN02v2_RS10155	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCCCN02v2_RS10175	COG3279	Response regulator of the LytR AlgR family
XCCCN02v2_RS10195	COG2198	Histidine kinase
XCCCN02v2_RS10195	COG0784	Response regulator, receiver
XCCCN02v2_RS10195	COG2205	protein histidine kinase activity
XCCCN02v2_RS10200	COG2205	protein histidine kinase activity
XCCCN02v2_RS10200	COG2198	Histidine kinase
XCCCN02v2_RS10200	COG0784	Response regulator, receiver
XCCCN02v2_RS10205	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS10210	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN02v2_RS10240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN02v2_RS10270	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10280	COG0835	chemotaxis
XCCCN02v2_RS10290	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10300	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10305	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10310	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10315	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10320	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10325	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10335	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS10345	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS10360	COG1192	Involved in chromosome partitioning
XCCCN02v2_RS10365	COG1360	Flagellar Motor Protein
XCCCN02v2_RS10370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCCCN02v2_RS10485	COG2198	Histidine kinase
XCCCN02v2_RS10485	COG0784	Response regulator, receiver
XCCCN02v2_RS10485	COG0643	Histidine kinase
XCCCN02v2_RS10540	COG1684	flagellar biosynthetic protein fliR
XCCCN02v2_RS10545	COG1987	bacterial-type flagellum assembly
XCCCN02v2_RS10610	COG1677	Flagellar hook-basal body complex protein FliE
XCCCN02v2_RS10655	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS10660	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS10665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN02v2_RS10685	COG2201	protein-glutamate methylesterase activity
XCCCN02v2_RS10715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCCCN02v2_RS10720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN02v2_RS10725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN02v2_RS10735	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCCCN02v2_RS10735	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCCCN02v2_RS10755	COG4787	bacterial-type flagellum-dependent cell motility
XCCCN02v2_RS10765	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCCCN02v2_RS10770	COG1558	bacterial-type flagellum-dependent cell motility
XCCCN02v2_RS10780	COG0784	Response regulator, receiver
XCCCN02v2_RS10780	COG0835	chemotaxis
XCCCN02v2_RS10800	COG4191	Histidine kinase
XCCCN02v2_RS10835	COG2915	High frequency lysogenization protein hflD homolog
XCCCN02v2_RS10855	COG0542	response to heat
XCCCN02v2_RS10875	COG0492	ferredoxin-NADP+ reductase activity
XCCCN02v2_RS10880	COG1674	ftsk spoiiie
XCCCN02v2_RS10900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCCCN02v2_RS10905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCCCN02v2_RS10910	COG0183	Belongs to the thiolase family
XCCCN02v2_RS10915	COG1024	Enoyl-CoA hydratase
XCCCN02v2_RS10915	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCCCN02v2_RS10950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN02v2_RS10965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCCCN02v2_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS10985	COG2124	cytochrome p450
XCCCN02v2_RS11010	COG0708	Exodeoxyribonuclease III
XCCCN02v2_RS11020	COG0303	'Molybdopterin
XCCCN02v2_RS11025	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN02v2_RS11035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCCCN02v2_RS11035	COG1648	precorrin-2 dehydrogenase activity
XCCCN02v2_RS11045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCCCN02v2_RS11050	COG2223	nitrite transmembrane transporter activity
XCCCN02v2_RS11055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCCCN02v2_RS11065	COG0243	molybdopterin cofactor binding
XCCCN02v2_RS11085	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCCCN02v2_RS11095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN02v2_RS11110	COG0579	oxidoreductase
XCCCN02v2_RS11135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN02v2_RS11175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN02v2_RS11255	COG3685	Protein conserved in bacteria
XCCCN02v2_RS11260	COG2201	protein-glutamate methylesterase activity
XCCCN02v2_RS11270	COG5001	Diguanylate cyclase
XCCCN02v2_RS11340	COG3590	peptidase
XCCCN02v2_RS11355	COG1999	signal sequence binding
XCCCN02v2_RS11370	COG1733	regulation of RNA biosynthetic process
XCCCN02v2_RS11400	COG1238	metal cluster binding
XCCCN02v2_RS11410	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS11445	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS11450	COG4191	Histidine kinase
XCCCN02v2_RS11450	COG0784	Response regulator, receiver
XCCCN02v2_RS11465	COG3279	Response regulator of the LytR AlgR family
XCCCN02v2_RS11670	COG1196	nuclear chromosome segregation
XCCCN02v2_RS11895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN02v2_RS11930	COG0428	transporter
XCCCN02v2_RS11940	COG1530	ribonuclease E activity
XCCCN02v2_RS11975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCCCN02v2_RS12005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN02v2_RS12020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCCCN02v2_RS12040	COG0848	biopolymer transport protein
XCCCN02v2_RS12045	COG0811	peptide transport
XCCCN02v2_RS12065	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCCCN02v2_RS12080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCCCN02v2_RS12095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCCCN02v2_RS12110	COG0354	folic acid binding
XCCCN02v2_RS12120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN02v2_RS12130	COG0363	glucosamine-6-phosphate deaminase activity
XCCCN02v2_RS12135	COG0129	dihydroxy-acid dehydratase activity
XCCCN02v2_RS12140	COG0800	Aldolase
XCCCN02v2_RS12205	COG5001	Diguanylate cyclase
XCCCN02v2_RS12210	COG2183	response to ionizing radiation
XCCCN02v2_RS12220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN02v2_RS12220	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN02v2_RS12235	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCCCN02v2_RS12245	COG1183	phosphatidylcholine synthase activity
XCCCN02v2_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS12280	COG0668	transmembrane transport
XCCCN02v2_RS12300	COG1914	H( )-stimulated, divalent metal cation uptake system
XCCCN02v2_RS12315	COG2814	Major facilitator Superfamily
XCCCN02v2_RS12330	COG1335	isochorismatase
XCCCN02v2_RS12345	COG2197	response regulator
XCCCN02v2_RS12370	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN02v2_RS12395	COG0475	glutathione-regulated potassium exporter activity
XCCCN02v2_RS12395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN02v2_RS12400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCCCN02v2_RS12415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCCCN02v2_RS12430	COG0539	negative regulation of cytoplasmic translation
XCCCN02v2_RS12450	COG2957	Belongs to the agmatine deiminase family
XCCCN02v2_RS12455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN02v2_RS12480	COG0395	ABC-type sugar transport system, permease component
XCCCN02v2_RS12515	COG2350	Protein conserved in bacteria
XCCCN02v2_RS12520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCCCN02v2_RS12525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCCCN02v2_RS12530	COG1187	pseudouridine synthase activity
XCCCN02v2_RS12555	COG0436	Aminotransferase
XCCCN02v2_RS12620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCCCN02v2_RS12625	COG4988	ABC transporter
XCCCN02v2_RS12635	COG1294	oxidase, subunit
XCCCN02v2_RS12670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XCCCN02v2_RS12700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCCCN02v2_RS12705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN02v2_RS12710	COG0137	argininosuccinate synthase activity
XCCCN02v2_RS12720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCCCN02v2_RS12735	COG2166	iron-sulfur cluster assembly
XCCCN02v2_RS12765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCCCN02v2_RS12785	COG4302	ethanolamine ammonia-lyase activity
XCCCN02v2_RS12835	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN02v2_RS12850	COG1509	lysine 2,3-aminomutase activity
XCCCN02v2_RS12855	COG5001	Diguanylate cyclase
XCCCN02v2_RS12855	COG3300	MHYT domain
XCCCN02v2_RS12870	COG0483	inositol monophosphate 1-phosphatase activity
XCCCN02v2_RS12875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN02v2_RS12890	COG0488	(ABC) transporter
XCCCN02v2_RS12895	COG0513	Belongs to the DEAD box helicase family
XCCCN02v2_RS12930	COG4681	YaeQ
XCCCN02v2_RS12935	COG2081	HI0933 family
XCCCN02v2_RS12940	COG3300	MHYT domain
XCCCN02v2_RS12940	COG5001	Diguanylate cyclase
XCCCN02v2_RS12955	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS12980	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN02v2_RS12990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCCCN02v2_RS12990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN02v2_RS12995	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCCCN02v2_RS13010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN02v2_RS13040	COG0582	viral genome integration into host DNA
XCCCN02v2_RS13085	COG0835	chemotaxis
XCCCN02v2_RS13090	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS13100	COG1201	RNA secondary structure unwinding
XCCCN02v2_RS13115	COG2969	positive regulation of protein catabolic process
XCCCN02v2_RS13120	COG0625	glutathione transferase activity
XCCCN02v2_RS13125	COG2857	Cytochrome c1
XCCCN02v2_RS13130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCCCN02v2_RS13135	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN02v2_RS13140	COG0741	lytic transglycosylase activity
XCCCN02v2_RS13160	COG1702	phosphate starvation-inducible protein PhoH
XCCCN02v2_RS13180	COG4535	Mg2 and Co2 transporter CorC
XCCCN02v2_RS13195	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN02v2_RS13205	COG1177	transmembrane transport
XCCCN02v2_RS13210	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCCCN02v2_RS13220	COG3842	ATPase activity
XCCCN02v2_RS13255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCCCN02v2_RS13260	COG0174	glutamine synthetase
XCCCN02v2_RS13265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN02v2_RS13275	COG2703	oxygen carrier activity
XCCCN02v2_RS13290	COG0243	molybdopterin cofactor binding
XCCCN02v2_RS13300	COG2223	nitrite transmembrane transporter activity
XCCCN02v2_RS13305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCCCN02v2_RS13315	COG2733	membrane
XCCCN02v2_RS13320	COG0784	Response regulator, receiver
XCCCN02v2_RS13320	COG2205	protein histidine kinase activity
XCCCN02v2_RS13320	COG5002	protein histidine kinase activity
XCCCN02v2_RS13330	COG0477	Major facilitator Superfamily
XCCCN02v2_RS13335	COG1335	isochorismatase
XCCCN02v2_RS13340	COG2207	Transcriptional regulator
XCCCN02v2_RS13340	COG1609	Transcriptional regulator
XCCCN02v2_RS13345	COG2902	Dehydrogenase
XCCCN02v2_RS13360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN02v2_RS13365	COG1609	Transcriptional regulator
XCCCN02v2_RS13370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN02v2_RS13370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN02v2_RS13375	COG1105	Belongs to the carbohydrate kinase PfkB family
XCCCN02v2_RS13380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN02v2_RS13380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN02v2_RS13395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCCCN02v2_RS13405	COG1862	Preprotein translocase
XCCCN02v2_RS13425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCCCN02v2_RS13455	COG3291	Pkd domain containing protein
XCCCN02v2_RS13460	COG0405	Gamma-glutamyltransferase
XCCCN02v2_RS13465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCCCN02v2_RS13480	COG0742	ribosomal rna small subunit methyltransferase
XCCCN02v2_RS13485	COG0326	Molecular chaperone. Has ATPase activity
XCCCN02v2_RS13560	COG0531	amino acid
XCCCN02v2_RS13585	COG0006	proline dipeptidase activity
XCCCN02v2_RS13595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN02v2_RS13615	COG3938	Belongs to the proline racemase family
XCCCN02v2_RS13625	COG0552	protein localization to endoplasmic reticulum
XCCCN02v2_RS13645	COG4191	Histidine kinase
XCCCN02v2_RS13645	COG0784	Response regulator, receiver
XCCCN02v2_RS13655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN02v2_RS13700	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS13730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN02v2_RS13735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN02v2_RS13740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN02v2_RS13765	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS13770	COG2244	polysaccharide biosynthetic process
XCCCN02v2_RS13775	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS13780	COG0438	transferase activity, transferring glycosyl groups
XCCCN02v2_RS13850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCCCN02v2_RS13880	COG1082	Xylose isomerase domain protein TIM barrel
XCCCN02v2_RS13895	COG0366	Alpha amylase catalytic
XCCCN02v2_RS13915	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN02v2_RS13915	COG3501	Rhs element vgr protein
XCCCN02v2_RS13945	COG3702	type iv secretory pathway
XCCCN02v2_RS13965	COG2948	multi-organism process
XCCCN02v2_RS13985	COG3505	Type IV secretory pathway VirD4
XCCCN02v2_RS14005	COG4969	Belongs to the N-Me-Phe pilin family
XCCCN02v2_RS14050	COG3275	phosphorelay sensor kinase activity
XCCCN02v2_RS14055	COG1611	Belongs to the LOG family
XCCCN02v2_RS14065	COG2095	MarC family integral membrane protein
XCCCN02v2_RS14075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN02v2_RS14135	COG0195	Participates in both transcription termination and antitermination
XCCCN02v2_RS14150	COG1007	ATP synthesis coupled electron transport
XCCCN02v2_RS14170	COG0839	Belongs to the complex I subunit 6 family
XCCCN02v2_RS14190	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCCCN02v2_RS14195	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCCCN02v2_RS14215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCCCN02v2_RS14235	COG0300	oxidoreductase activity
XCCCN02v2_RS14325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCCCN02v2_RS14330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCCCN02v2_RS14345	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN02v2_RS14370	COG0433	COG0433 Predicted ATPase
XCCCN02v2_RS14385	COG0494	nUDIX hydrolase
XCCCN02v2_RS14430	COG0717	Belongs to the dCTP deaminase family
XCCCN02v2_RS14435	COG0489	protein tyrosine kinase activity
XCCCN02v2_RS14455	COG3590	peptidase
XCCCN02v2_RS14460	COG3590	peptidase
XCCCN02v2_RS14480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN02v2_RS14485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN02v2_RS14490	COG2311	Membrane
XCCCN02v2_RS14495	COG1047	Peptidyl-prolyl cis-trans
XCCCN02v2_RS14500	COG0791	NLP P60 protein
XCCCN02v2_RS14505	COG0791	NLP P60 protein
XCCCN02v2_RS14535	COG4191	Histidine kinase
XCCCN02v2_RS14550	COG4106	trans-aconitate 2-methyltransferase activity
XCCCN02v2_RS14555	COG1301	dicarboxylic acid transport
XCCCN02v2_RS14575	COG0142	geranyltranstransferase activity
XCCCN02v2_RS14595	COG0312	modulator of DNA gyrase
XCCCN02v2_RS14605	COG0312	modulator of DNA gyrase
XCCCN02v2_RS14615	COG3164	Protein of unknown function
XCCCN02v2_RS14630	COG2968	Membrane
XCCCN02v2_RS14660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCCCN02v2_RS14685	COG3118	belongs to the thioredoxin family
XCCCN02v2_RS14695	COG2155	Conserved Protein
XCCCN02v2_RS14750	COG1132	(ABC) transporter
XCCCN02v2_RS14755	COG0475	glutathione-regulated potassium exporter activity
XCCCN02v2_RS14780	COG1187	pseudouridine synthase activity
XCCCN02v2_RS14785	COG5002	protein histidine kinase activity
XCCCN02v2_RS14785	COG5001	Diguanylate cyclase
XCCCN02v2_RS14880	COG1294	oxidase, subunit
XCCCN02v2_RS14885	COG1271	oxidase subunit
XCCCN02v2_RS14895	COG3383	formate dehydrogenase (NAD+) activity
XCCCN02v2_RS14925	COG2814	Major facilitator Superfamily
XCCCN02v2_RS14930	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS14950	COG2207	Transcriptional regulator
XCCCN02v2_RS14965	COG0667	Aldo Keto reductase
XCCCN02v2_RS14970	COG1309	transcriptional regulator
XCCCN02v2_RS14980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN02v2_RS14995	COG0735	belongs to the Fur family
XCCCN02v2_RS15030	COG4452	Inner membrane protein CreD
XCCCN02v2_RS15035	COG2205	protein histidine kinase activity
XCCCN02v2_RS15040	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS15045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCCCN02v2_RS15060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCCCN02v2_RS15070	COG2198	Histidine kinase
XCCCN02v2_RS15070	COG0643	Histidine kinase
XCCCN02v2_RS15075	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS15080	COG0835	chemotaxis
XCCCN02v2_RS15090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN02v2_RS15100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS15105	COG3590	peptidase
XCCCN02v2_RS15125	COG1741	Belongs to the pirin family
XCCCN02v2_RS15145	COG1741	Belongs to the pirin family
XCCCN02v2_RS15150	COG1966	Carbon starvation protein
XCCCN02v2_RS15155	COG2879	small protein
XCCCN02v2_RS15190	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCCCN02v2_RS15195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN02v2_RS15200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN02v2_RS15205	COG2080	2 iron, 2 sulfur cluster binding
XCCCN02v2_RS15210	COG0604	alcohol dehydrogenase
XCCCN02v2_RS15215	COG5001	Diguanylate cyclase
XCCCN02v2_RS15215	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS15215	COG2203	Gaf domain
XCCCN02v2_RS15215	COG3706	GGDEF domain
XCCCN02v2_RS15220	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS15225	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS15235	COG3713	MltA-interacting MipA family protein
XCCCN02v2_RS15245	COG0629	single-stranded DNA binding
XCCCN02v2_RS15250	COG0142	geranyltranstransferase activity
XCCCN02v2_RS15275	COG0527	aspartate kinase activity
XCCCN02v2_RS15280	COG0384	phenazine biosynthesis protein PhzF
XCCCN02v2_RS15285	COG0384	phenazine biosynthesis protein PhzF
XCCCN02v2_RS15295	COG1764	response to oxidative stress
XCCCN02v2_RS15315	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCCCN02v2_RS15320	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN02v2_RS15350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCCCN02v2_RS15385	COG0693	protein deglycase activity
XCCCN02v2_RS15400	COG0719	Fe-S assembly protein
XCCCN02v2_RS15405	COG0396	ATPase activity
XCCCN02v2_RS15410	COG0719	Fe-S assembly protein
XCCCN02v2_RS15415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN02v2_RS15425	COG2146	nitrite reductase [NAD(P)H] activity
XCCCN02v2_RS15430	COG4774	siderophore transport
XCCCN02v2_RS15475	COG1555	photosystem II stabilization
XCCCN02v2_RS15480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN02v2_RS15495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN02v2_RS15505	COG0628	permease
XCCCN02v2_RS15525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCCCN02v2_RS15550	COG0271	Belongs to the BolA IbaG family
XCCCN02v2_RS15560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCCCN02v2_RS15575	COG1137	ATPase activity
XCCCN02v2_RS15590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN02v2_RS15610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN02v2_RS15615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN02v2_RS15620	COG2239	Acts as a magnesium transporter
XCCCN02v2_RS15630	COG1294	oxidase, subunit
XCCCN02v2_RS15640	COG1113	amino acid transport
XCCCN02v2_RS15660	COG2197	response regulator
XCCCN02v2_RS15665	COG0531	amino acid
XCCCN02v2_RS15735	COG2814	Major facilitator Superfamily
XCCCN02v2_RS15745	COG0754	glutathionylspermidine amidase activity
XCCCN02v2_RS15770	COG1842	Phage shock protein A
XCCCN02v2_RS15805	COG0477	Major facilitator Superfamily
XCCCN02v2_RS15825	COG2353	YceI-like domain
XCCCN02v2_RS15845	COG1760	l-serine dehydratase
XCCCN02v2_RS15860	COG0527	aspartate kinase activity
XCCCN02v2_RS15860	COG0460	homoserine dehydrogenase
XCCCN02v2_RS15865	COG0626	cystathionine gamma-synthase activity
XCCCN02v2_RS15870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN02v2_RS15885	COG1272	protein, Hemolysin III
XCCCN02v2_RS15890	COG2982	Protein involved in outer membrane biogenesis
XCCCN02v2_RS15895	COG0516	GMP reductase activity
XCCCN02v2_RS15895	COG0517	IMP dehydrogenase activity
XCCCN02v2_RS15900	COG0463	Glycosyl transferase, family 2
XCCCN02v2_RS15910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCCCN02v2_RS15925	COG1309	transcriptional regulator
XCCCN02v2_RS15930	COG2267	carboxylic ester hydrolase activity
XCCCN02v2_RS15935	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS15985	COG0330	HflC and HflK could
XCCCN02v2_RS16000	COG3956	TIGRFAM MazG family protein
XCCCN02v2_RS16005	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCCCN02v2_RS16010	COG0494	nUDIX hydrolase
XCCCN02v2_RS16020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCCCN02v2_RS16045	COG1388	LysM domain
XCCCN02v2_RS16045	COG3858	chitin binding
XCCCN02v2_RS16050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCCCN02v2_RS16060	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN02v2_RS16070	COG3537	Alpha-1,2-mannosidase
XCCCN02v2_RS16115	COG3645	SOS response
XCCCN02v2_RS16130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN02v2_RS16175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XCCCN02v2_RS16190	COG1446	asparaginase
XCCCN02v2_RS16200	COG1595	DNA-templated transcription, initiation
XCCCN02v2_RS16230	COG2198	Histidine kinase
XCCCN02v2_RS16230	COG0784	Response regulator, receiver
XCCCN02v2_RS16230	COG0643	Histidine kinase
XCCCN02v2_RS16235	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS16240	COG0835	chemotaxis
XCCCN02v2_RS16255	COG0189	ligase activity
XCCCN02v2_RS16280	COG1199	ATP-dependent helicase activity
XCCCN02v2_RS16290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCCCN02v2_RS16295	COG1215	transferase activity, transferring glycosyl groups
XCCCN02v2_RS16305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN02v2_RS16355	COG1643	Atp-dependent helicase
XCCCN02v2_RS16360	COG0783	Belongs to the Dps family
XCCCN02v2_RS16365	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN02v2_RS16380	COG1187	pseudouridine synthase activity
XCCCN02v2_RS16405	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS16450	COG0602	queuosine metabolic process
XCCCN02v2_RS16460	COG2885	chlorophyll binding
XCCCN02v2_RS16475	COG0848	biopolymer transport protein
XCCCN02v2_RS16485	COG0824	Thioesterase
XCCCN02v2_RS16555	COG0477	Major facilitator Superfamily
XCCCN02v2_RS16575	COG2755	lipolytic protein G-D-S-L family
XCCCN02v2_RS16575	COG0657	acetylesterase activity
XCCCN02v2_RS16595	COG0488	(ABC) transporter
XCCCN02v2_RS16635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN02v2_RS16635	COG4651	solute:proton antiporter activity
XCCCN02v2_RS16645	COG4772	TonB-dependent receptor
XCCCN02v2_RS16655	COG4264	IucA IucC family
XCCCN02v2_RS16660	COG2814	Major facilitator Superfamily
XCCCN02v2_RS16665	COG4264	IucA IucC family
XCCCN02v2_RS16670	COG0019	diaminopimelate decarboxylase activity
XCCCN02v2_RS16685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCCCN02v2_RS16715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN02v2_RS16720	COG1797	cobyrinic acid a,c-diamide synthase activity
XCCCN02v2_RS16740	COG4206	TonB-dependent receptor
XCCCN02v2_RS16755	COG0542	response to heat
XCCCN02v2_RS16760	COG1116	anion transmembrane transporter activity
XCCCN02v2_RS16805	COG1877	trehalose-phosphatase activity
XCCCN02v2_RS16825	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS16845	COG0564	pseudouridine synthase activity
XCCCN02v2_RS16850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN02v2_RS16860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCCCN02v2_RS16860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN02v2_RS16910	COG1459	type II secretion system
XCCCN02v2_RS16915	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCCCN02v2_RS16950	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS17010	COG0210	DNA helicase
XCCCN02v2_RS17035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN02v2_RS17065	COG2003	Belongs to the UPF0758 family
XCCCN02v2_RS17095	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS17110	COG0745	RESPONSE REGULATOR receiver
XCCCN02v2_RS17110	COG2205	protein histidine kinase activity
XCCCN02v2_RS17110	COG4191	Histidine kinase
XCCCN02v2_RS17115	COG3781	membrane
XCCCN02v2_RS17125	COG2814	Major facilitator Superfamily
XCCCN02v2_RS17135	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS17270	COG0471	metal ion transport
XCCCN02v2_RS17270	COG3273	potassium ion transport
XCCCN02v2_RS17300	COG1609	Transcriptional regulator
XCCCN02v2_RS17315	COG3250	beta-galactosidase activity
XCCCN02v2_RS17320	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN02v2_RS17325	COG2272	Belongs to the type-B carboxylesterase lipase family
XCCCN02v2_RS17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN02v2_RS17335	COG1115	amino acid carrier protein
XCCCN02v2_RS17345	COG0308	aminopeptidase N
XCCCN02v2_RS17350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN02v2_RS17355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN02v2_RS17360	COG2895	sulfate adenylyltransferase (ATP) activity
XCCCN02v2_RS17360	COG0529	Catalyzes the synthesis of activated sulfate
XCCCN02v2_RS17370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN02v2_RS17400	COG2198	Histidine kinase
XCCCN02v2_RS17400	COG0784	Response regulator, receiver
XCCCN02v2_RS17400	COG2205	protein histidine kinase activity
XCCCN02v2_RS17430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCCCN02v2_RS17435	COG3588	fructose-bisphosphate aldolase
XCCCN02v2_RS17440	COG0469	pyruvate kinase activity
XCCCN02v2_RS17475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCCCN02v2_RS17490	COG3047	cAMP biosynthetic process
XCCCN02v2_RS17505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN02v2_RS17505	COG3453	Protein conserved in bacteria
XCCCN02v2_RS17510	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCCCN02v2_RS17515	COG4149	molybdate abc transporter
XCCCN02v2_RS17545	COG1376	ErfK ybiS ycfS ynhG family protein
XCCCN02v2_RS17550	COG0739	heme binding
XCCCN02v2_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS17560	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS17565	COG4773	Receptor
XCCCN02v2_RS17570	COG0596	Alpha beta hydrolase
XCCCN02v2_RS17575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCCCN02v2_RS17580	COG1301	dicarboxylic acid transport
XCCCN02v2_RS17590	COG2304	oxidoreductase activity
XCCCN02v2_RS17610	COG0714	Associated with various cellular activities
XCCCN02v2_RS17640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCCCN02v2_RS17665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCCCN02v2_RS17675	COG2721	sulfolactate sulfo-lyase activity
XCCCN02v2_RS17690	COG2271	Major facilitator Superfamily
XCCCN02v2_RS17705	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS17715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN02v2_RS17730	COG1561	YicC-like family, N-terminal region
XCCCN02v2_RS17740	COG0346	lactoylglutathione lyase activity
XCCCN02v2_RS17750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCCCN02v2_RS17775	COG0006	proline dipeptidase activity
XCCCN02v2_RS17800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCCCN02v2_RS17820	COG2912	Transglutaminase-like superfamily
XCCCN02v2_RS17825	COG1773	rubredoxin
XCCCN02v2_RS17855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN02v2_RS17885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCCCN02v2_RS17890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN02v2_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS17910	COG0671	phosphoesterase, PA-phosphatase related
XCCCN02v2_RS17915	COG3781	membrane
XCCCN02v2_RS17925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCCCN02v2_RS17940	COG3039	Transposase
XCCCN02v2_RS17955	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCCCN02v2_RS17970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCCCN02v2_RS18005	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN02v2_RS18005	COG1506	peptidase
XCCCN02v2_RS18005	COG4946	Tricorn protease homolog
XCCCN02v2_RS18010	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS18015	COG0405	Gamma-glutamyltransferase
XCCCN02v2_RS18050	COG2226	methyltransferase
XCCCN02v2_RS18060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCCCN02v2_RS18070	COG3300	MHYT domain
XCCCN02v2_RS18070	COG5001	Diguanylate cyclase
XCCCN02v2_RS18080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCCCN02v2_RS18085	COG1538	Outer membrane efflux protein
XCCCN02v2_RS18090	COG1519	Transferase
XCCCN02v2_RS18095	COG1560	Kdo2-lipid A biosynthetic process
XCCCN02v2_RS18135	COG4191	Histidine kinase
XCCCN02v2_RS18145	COG2197	response regulator
XCCCN02v2_RS18155	COG0642	Histidine kinase
XCCCN02v2_RS18170	COG2851	Citrate transporter
XCCCN02v2_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS18180	COG1609	Transcriptional regulator
XCCCN02v2_RS18185	COG2211	Major facilitator Superfamily
XCCCN02v2_RS18210	COG1162	GTPase activity
XCCCN02v2_RS18255	COG0436	Aminotransferase
XCCCN02v2_RS18275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN02v2_RS18295	COG1228	amidohydrolase
XCCCN02v2_RS18335	COG1307	EDD domain protein, DegV family
XCCCN02v2_RS18345	COG0697	spore germination
XCCCN02v2_RS18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN02v2_RS18365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCCCN02v2_RS18385	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS18405	COG2205	protein histidine kinase activity
XCCCN02v2_RS18430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN02v2_RS18440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCCCN02v2_RS18480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCCCN02v2_RS18485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN02v2_RS18490	COG1609	Transcriptional regulator
XCCCN02v2_RS18500	COG2188	Transcriptional regulator
XCCCN02v2_RS18525	COG4795	General secretion pathway protein
XCCCN02v2_RS18530	COG2165	general secretion pathway protein
XCCCN02v2_RS18545	COG1459	type II secretion system
XCCCN02v2_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS18595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCCCN02v2_RS18600	COG4191	Histidine kinase
XCCCN02v2_RS18605	COG0784	Response regulator, receiver
XCCCN02v2_RS18610	COG4251	negative regulation of phosphorylation
XCCCN02v2_RS18615	COG2823	Periplasmic or secreted lipoprotein
XCCCN02v2_RS18620	COG0673	inositol 2-dehydrogenase activity
XCCCN02v2_RS18625	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCCCN02v2_RS18660	COG1051	belongs to the nudix hydrolase family
XCCCN02v2_RS18660	COG1056	cytidyltransferase-related domain
XCCCN02v2_RS18705	COG1686	Belongs to the peptidase S11 family
XCCCN02v2_RS18710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCCCN02v2_RS18715	COG2951	lytic endotransglycosylase activity
XCCCN02v2_RS18755	COG0772	Belongs to the SEDS family
XCCCN02v2_RS18770	COG1792	Involved in formation and maintenance of cell shape
XCCCN02v2_RS18780	COG1077	Cell shape determining protein MreB Mrl
XCCCN02v2_RS18785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN02v2_RS18790	COG3284	Transcriptional regulator
XCCCN02v2_RS18800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCCCN02v2_RS18835	COG0308	aminopeptidase N
XCCCN02v2_RS18840	COG5001	Diguanylate cyclase
XCCCN02v2_RS18840	COG3300	MHYT domain
XCCCN02v2_RS18845	COG2226	methyltransferase
XCCCN02v2_RS18905	COG2832	Protein of unknown function (DUF454)
XCCCN02v2_RS18915	COG0436	Aminotransferase
XCCCN02v2_RS18930	COG1505	serine-type exopeptidase activity
XCCCN02v2_RS18970	COG3275	phosphorelay sensor kinase activity
XCCCN02v2_RS18985	COG3273	potassium ion transport
XCCCN02v2_RS18985	COG0471	metal ion transport
XCCCN02v2_RS19000	COG3706	GGDEF domain
XCCCN02v2_RS19005	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN02v2_RS19010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN02v2_RS19010	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN02v2_RS19020	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS19080	COG1113	amino acid transport
XCCCN02v2_RS19090	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN02v2_RS19095	COG4305	rare lipoprotein A
XCCCN02v2_RS19110	COG0697	spore germination
XCCCN02v2_RS19145	COG1959	2 iron, 2 sulfur cluster binding
XCCCN02v2_RS19160	COG1506	peptidase
XCCCN02v2_RS19160	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN02v2_RS19170	COG2409	Drug exporters of the RND superfamily
XCCCN02v2_RS19230	COG0435	Glutathione S-transferase
XCCCN02v2_RS19280	COG0367	asparagine synthase
XCCCN02v2_RS19285	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN02v2_RS19285	COG1506	peptidase
XCCCN02v2_RS19300	COG1595	DNA-templated transcription, initiation
XCCCN02v2_RS19415	COG1802	Transcriptional regulator
XCCCN02v2_RS19470	COG2353	YceI-like domain
XCCCN02v2_RS19495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN02v2_RS19535	COG3712	iron ion homeostasis
XCCCN02v2_RS19550	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN02v2_RS19580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCCCN02v2_RS19590	COG3550	peptidyl-serine autophosphorylation
XCCCN02v2_RS19620	COG1196	nuclear chromosome segregation
XCCCN02v2_RS19630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCCCN02v2_RS19645	COG2356	endonuclease I
XCCCN02v2_RS19650	COG1324	tolerance protein
XCCCN02v2_RS19665	COG0511	ligase activity, forming carbon-carbon bonds
XCCCN02v2_RS19675	COG0439	Biotin carboxylase
XCCCN02v2_RS19710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCCCN02v2_RS19725	COG4589	Belongs to the CDS family
XCCCN02v2_RS19750	COG0671	phosphoesterase, PA-phosphatase related
XCCCN02v2_RS19750	COG2453	phosphatase
XCCCN02v2_RS19755	COG2267	carboxylic ester hydrolase activity
XCCCN02v2_RS19760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN02v2_RS19775	COG0151	Belongs to the GarS family
XCCCN02v2_RS19780	COG1289	transmembrane transporter activity
XCCCN02v2_RS19790	COG2814	Major facilitator Superfamily
XCCCN02v2_RS19820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN02v2_RS19825	COG2816	NAD+ diphosphatase activity
XCCCN02v2_RS19930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCCCN02v2_RS19945	COG0436	Aminotransferase
XCCCN02v2_RS20025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCCCN02v2_RS20025	COG2111	Na H antiporter
XCCCN02v2_RS20030	COG1006	Multisubunit Na H antiporter MnhC subunit
XCCCN02v2_RS20035	COG0651	ATP synthesis coupled electron transport
XCCCN02v2_RS20045	COG2212	antiporter activity
XCCCN02v2_RS20050	COG1320	monovalent cation:proton antiporter activity
XCCCN02v2_RS20075	COG2852	Protein conserved in bacteria
XCCCN02v2_RS20095	COG3104	oligopeptide transport
XCCCN02v2_RS20110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCCCN02v2_RS20125	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN02v2_RS20135	COG0513	Belongs to the DEAD box helicase family
XCCCN02v2_RS20150	COG2085	NADP oxidoreductase coenzyme F420-dependent
XCCCN02v2_RS20155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN02v2_RS20200	COG0702	epimerase
XCCCN02v2_RS20225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCCCN02v2_RS20235	COG0297	glycogen (starch) synthase activity
XCCCN02v2_RS20245	COG1649	PFAM Uncharacterised BCR, COG1649
XCCCN02v2_RS20250	COG2354	Protein conserved in bacteria
XCCCN02v2_RS20255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCCCN02v2_RS20270	COG3264	Mechanosensitive ion channel
XCCCN02v2_RS20270	COG1511	domain protein
XCCCN02v2_RS20290	COG4206	TonB-dependent receptor
XCCCN02v2_RS20310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN02v2_RS20315	COG4774	siderophore transport
XCCCN02v2_RS20325	COG0582	viral genome integration into host DNA
XCCCN02v2_RS20340	COG1040	competence protein
XCCCN02v2_RS20390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCCCN02v2_RS20410	COG0657	acetylesterase activity
XCCCN02v2_RS20420	COG1414	Transcriptional regulator
XCCCN02v2_RS20430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCCCN02v2_RS20435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN02v2_RS20440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XCCCN02v2_RS20445	COG3485	protocatechuate 3,4-dioxygenase
XCCCN02v2_RS20450	COG3485	protocatechuate 3,4-dioxygenase
XCCCN02v2_RS20460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN02v2_RS20465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN02v2_RS20490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCCCN02v2_RS20555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCCCN02v2_RS20640	COG3039	Transposase
XCCCN02v2_RS20675	COG3039	Transposase
XCCCN02v2_RS20710	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS20720	COG1733	regulation of RNA biosynthetic process
XCCCN02v2_RS20725	COG0702	epimerase
XCCCN02v2_RS20735	COG3321	synthase
XCCCN02v2_RS20735	COG0604	alcohol dehydrogenase
XCCCN02v2_RS20740	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS20765	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS20770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN02v2_RS20795	COG1902	pentaerythritol trinitrate reductase activity
XCCCN02v2_RS20820	COG2814	Major facilitator Superfamily
XCCCN02v2_RS20825	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS20835	COG0084	hydrolase, TatD family'
XCCCN02v2_RS20855	COG2252	PERMEase
XCCCN02v2_RS20865	COG1957	nucleoside hydrolase
XCCCN02v2_RS20880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS20910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCCCN02v2_RS20930	COG2072	flavoprotein involved in K transport
XCCCN02v2_RS20935	COG2351	hydroxyisourate hydrolase activity
XCCCN02v2_RS20940	COG4807	Protein conserved in bacteria
XCCCN02v2_RS20945	COG0840	transmembrane signaling receptor activity
XCCCN02v2_RS20950	COG1643	Atp-dependent helicase
XCCCN02v2_RS20960	COG1187	pseudouridine synthase activity
XCCCN02v2_RS20975	COG2130	NADP-dependent
XCCCN02v2_RS20980	COG0656	L-ascorbic acid biosynthetic process
XCCCN02v2_RS21010	COG1764	response to oxidative stress
XCCCN02v2_RS21015	COG1846	Transcriptional regulator
XCCCN02v2_RS21025	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCCCN02v2_RS21035	COG0697	spore germination
XCCCN02v2_RS21045	COG0523	cobalamin synthesis protein
XCCCN02v2_RS21100	COG1960	acyl-CoA dehydrogenase activity
XCCCN02v2_RS21105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCCCN02v2_RS21110	COG4770	biotin carboxylase activity
XCCCN02v2_RS21140	COG3039	Transposase
XCCCN02v2_RS21145	COG2224	Isocitrate lyase
XCCCN02v2_RS21150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCCCN02v2_RS21155	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS21185	COG0339	signal peptide processing
XCCCN02v2_RS21190	COG1446	asparaginase
XCCCN02v2_RS21210	COG0564	pseudouridine synthase activity
XCCCN02v2_RS21225	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN02v2_RS21255	COG2091	lysine biosynthetic process via aminoadipic acid
XCCCN02v2_RS21315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCCCN02v2_RS21325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCCCN02v2_RS21330	COG3162	membrane
XCCCN02v2_RS21365	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN02v2_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN02v2_RS21385	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCCCN02v2_RS21390	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN02v2_RS21400	COG3254	rhamnose metabolic process
XCCCN02v2_RS21410	COG1414	Transcriptional regulator
XCCCN02v2_RS21430	COG0784	Response regulator, receiver
XCCCN02v2_RS21430	COG2205	protein histidine kinase activity
XCCCN02v2_RS21435	COG3459	Glycosyltransferase 36 associated
XCCCN02v2_RS21440	COG2211	Major facilitator Superfamily
XCCCN02v2_RS21445	COG3265	gluconokinase activity
XCCCN02v2_RS21450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN02v2_RS21470	COG2911	Protein conserved in bacteria
XCCCN02v2_RS21475	COG0729	surface antigen
XCCCN02v2_RS21490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN02v2_RS21495	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN02v2_RS21495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCCCN02v2_RS21510	COG0805	protein transport
XCCCN02v2_RS21530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCCCN02v2_RS21570	COG3661	Belongs to the glycosyl hydrolase 67 family
XCCCN02v2_RS21580	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN02v2_RS21590	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN02v2_RS21595	COG0246	Mannitol dehydrogenase
XCCCN02v2_RS21625	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN02v2_RS21645	COG3250	beta-galactosidase activity
XCCCN02v2_RS21655	COG3693	PFAM glycoside hydrolase, family 10
XCCCN02v2_RS21670	COG2211	Major facilitator Superfamily
XCCCN02v2_RS21710	COG2937	Belongs to the GPAT DAPAT family
XCCCN02v2_RS21745	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCCCN02v2_RS21765	COG0210	DNA helicase
XCCCN02v2_RS21795	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCCCN02v2_RS21840	COG3135	benzoate transporter
XCCCN02v2_RS21865	COG0676	glucose-6-phosphate 1-epimerase activity
XCCCN02v2_RS21885	COG0730	response to heat
XCCCN02v2_RS21915	COG0302	gtp cyclohydrolase
XCCCN02v2_RS21930	COG1566	PFAM secretion protein HlyD family protein
XCCCN02v2_RS21940	COG1289	transmembrane transporter activity
XCCCN02v2_RS21945	COG0477	Major facilitator Superfamily
XCCCN02v2_RS21955	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS21965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN02v2_RS21985	COG1487	ribonuclease activity
XCCCN02v2_RS22040	COG0564	pseudouridine synthase activity
XCCCN02v2_RS22090	COG1074	ATP-dependent DNA helicase activity
XCCCN02v2_RS22095	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCCCN02v2_RS22130	COG1127	ABC transporter
XCCCN02v2_RS22135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN02v2_RS22140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN02v2_RS22155	COG2853	Lipoprotein
XCCCN02v2_RS22165	COG0386	Belongs to the glutathione peroxidase family
XCCCN02v2_RS22175	COG1322	Protein conserved in bacteria
XCCCN02v2_RS22185	COG0604	alcohol dehydrogenase
XCCCN02v2_RS22190	COG0583	DNA-binding transcription factor activity
XCCCN02v2_RS22205	COG0531	amino acid
XCCCN02v2_RS22215	COG4206	TonB-dependent receptor
XCCCN02v2_RS22225	COG3706	GGDEF domain
XCCCN02v2_RS22230	COG3835	regulator
XCCCN02v2_RS22235	COG1929	Belongs to the glycerate kinase type-1 family
XCCCN02v2_RS22240	COG2271	Major facilitator Superfamily
XCCCN02v2_RS22265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCCCN02v2_RS22270	COG0861	Integral membrane protein TerC family
XCCCN02v2_RS22295	COG0584	glycerophosphoryl diester phosphodiesterase
XCCCN02v2_RS22310	COG0671	phosphoesterase, PA-phosphatase related
XCCCN02v2_RS22325	COG0726	polysaccharide deacetylase
XCCCN02v2_RS22330	COG0706	membrane insertase activity