locus-tag	class	description
XCCCN05v2_RS00020	COG0187	DNA topoisomerase II activity
XCCCN05v2_RS00030	COG0501	Belongs to the peptidase M48B family
XCCCN05v2_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN05v2_RS00110	COG0793	Belongs to the peptidase S41A family
XCCCN05v2_RS00115	COG4942	peptidase
XCCCN05v2_RS00125	COG2234	aminopeptidase activity
XCCCN05v2_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN05v2_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN05v2_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN05v2_RS00155	COG1064	alcohol dehydrogenase
XCCCN05v2_RS00170	COG0493	'glutamate synthase
XCCCN05v2_RS00175	COG0067	glutamate synthase
XCCCN05v2_RS00175	COG0069	glutamate synthase activity
XCCCN05v2_RS00175	COG0070	glutamate synthase
XCCCN05v2_RS00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCCCN05v2_RS00200	COG1741	Belongs to the pirin family
XCCCN05v2_RS00225	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS00285	COG1111	helicase
XCCCN05v2_RS00285	COG1205	dead DEAH box helicase
XCCCN05v2_RS00290	COG3177	Filamentation induced by cAMP protein fic
XCCCN05v2_RS00295	COG1272	protein, Hemolysin III
XCCCN05v2_RS00325	COG2249	NAD(P)H dehydrogenase (quinone) activity
XCCCN05v2_RS00340	COG0270	DNA (cytosine-5-)-methyltransferase activity
XCCCN05v2_RS00370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XCCCN05v2_RS00375	COG3237	CsbD-like
XCCCN05v2_RS00420	COG0628	permease
XCCCN05v2_RS00425	COG0657	acetylesterase activity
XCCCN05v2_RS00435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN05v2_RS00440	COG0477	Major facilitator Superfamily
XCCCN05v2_RS00485	COG0489	protein tyrosine kinase activity
XCCCN05v2_RS00620	COG0714	Associated with various cellular activities
XCCCN05v2_RS00650	COG3039	Transposase
XCCCN05v2_RS00665	COG4772	TonB-dependent receptor
XCCCN05v2_RS00680	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN05v2_RS00720	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCCCN05v2_RS00725	COG4585	Histidine kinase
XCCCN05v2_RS00730	COG2197	response regulator
XCCCN05v2_RS00760	COG3710	Transcriptional regulator
XCCCN05v2_RS00780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN05v2_RS00825	COG3039	Transposase
XCCCN05v2_RS00850	COG0366	Alpha amylase catalytic
XCCCN05v2_RS00855	COG0366	Alpha amylase catalytic
XCCCN05v2_RS00895	COG2755	lipolytic protein G-D-S-L family
XCCCN05v2_RS00900	COG2272	Belongs to the type-B carboxylesterase lipase family
XCCCN05v2_RS00905	COG2755	lipolytic protein G-D-S-L family
XCCCN05v2_RS00905	COG0657	acetylesterase activity
XCCCN05v2_RS00915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCCCN05v2_RS00930	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN05v2_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS00955	COG2755	lipolytic protein G-D-S-L family
XCCCN05v2_RS00965	COG3186	Phenylalanine-4-hydroxylase
XCCCN05v2_RS00970	COG1522	sequence-specific DNA binding
XCCCN05v2_RS00980	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCCCN05v2_RS00990	COG1119	ATPase activity
XCCCN05v2_RS01005	COG0517	IMP dehydrogenase activity
XCCCN05v2_RS01005	COG1125	glycine betaine transport
XCCCN05v2_RS01020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN05v2_RS01025	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCCCN05v2_RS01055	COG0489	protein tyrosine kinase activity
XCCCN05v2_RS01060	COG0588	phosphoglycerate mutase activity
XCCCN05v2_RS01070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS01095	COG1881	PFAM PEBP family protein
XCCCN05v2_RS01110	COG0174	glutamine synthetase
XCCCN05v2_RS01115	COG0347	Belongs to the P(II) protein family
XCCCN05v2_RS01120	COG0004	ammonium transporteR
XCCCN05v2_RS01125	COG3852	Histidine kinase
XCCCN05v2_RS01130	COG2204	response regulator
XCCCN05v2_RS01140	COG2032	superoxide dismutase activity
XCCCN05v2_RS01145	COG2032	superoxide dismutase activity
XCCCN05v2_RS01150	COG0346	lactoylglutathione lyase activity
XCCCN05v2_RS01160	COG0183	Belongs to the thiolase family
XCCCN05v2_RS01200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCCCN05v2_RS01220	COG0028	Belongs to the TPP enzyme family
XCCCN05v2_RS01235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCCCN05v2_RS01250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN05v2_RS01255	COG3177	Filamentation induced by cAMP protein fic
XCCCN05v2_RS01270	COG0596	Alpha beta hydrolase
XCCCN05v2_RS01275	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCCCN05v2_RS01280	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN05v2_RS01285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN05v2_RS01300	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN05v2_RS01315	COG0564	pseudouridine synthase activity
XCCCN05v2_RS01335	COG1446	asparaginase
XCCCN05v2_RS01340	COG0339	signal peptide processing
XCCCN05v2_RS01370	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS01375	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCCCN05v2_RS01380	COG2224	Isocitrate lyase
XCCCN05v2_RS01410	COG4770	biotin carboxylase activity
XCCCN05v2_RS01415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCCCN05v2_RS01420	COG1960	acyl-CoA dehydrogenase activity
XCCCN05v2_RS01485	COG0697	spore germination
XCCCN05v2_RS01495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCCCN05v2_RS01505	COG1846	Transcriptional regulator
XCCCN05v2_RS01510	COG1764	response to oxidative stress
XCCCN05v2_RS01540	COG0656	L-ascorbic acid biosynthetic process
XCCCN05v2_RS01545	COG2130	NADP-dependent
XCCCN05v2_RS01560	COG1187	pseudouridine synthase activity
XCCCN05v2_RS01570	COG1643	Atp-dependent helicase
XCCCN05v2_RS01575	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS01580	COG4807	Protein conserved in bacteria
XCCCN05v2_RS01585	COG2351	hydroxyisourate hydrolase activity
XCCCN05v2_RS01590	COG2072	flavoprotein involved in K transport
XCCCN05v2_RS01610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCCCN05v2_RS01635	COG3568	Endonuclease Exonuclease Phosphatase
XCCCN05v2_RS01640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS01655	COG1957	nucleoside hydrolase
XCCCN05v2_RS01665	COG2252	PERMEase
XCCCN05v2_RS01685	COG0084	hydrolase, TatD family'
XCCCN05v2_RS01695	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS01700	COG2814	Major facilitator Superfamily
XCCCN05v2_RS01725	COG1902	pentaerythritol trinitrate reductase activity
XCCCN05v2_RS01730	COG2084	Dehydrogenase
XCCCN05v2_RS01750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN05v2_RS01785	COG0702	epimerase
XCCCN05v2_RS01790	COG1733	regulation of RNA biosynthetic process
XCCCN05v2_RS01800	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS01870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCCCN05v2_RS01960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN05v2_RS01965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN05v2_RS01975	COG3485	protocatechuate 3,4-dioxygenase
XCCCN05v2_RS01980	COG3485	protocatechuate 3,4-dioxygenase
XCCCN05v2_RS01990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN05v2_RS01995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCCCN05v2_RS02005	COG1414	Transcriptional regulator
XCCCN05v2_RS02015	COG3039	Transposase
XCCCN05v2_RS02020	COG0657	acetylesterase activity
XCCCN05v2_RS02040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCCCN05v2_RS02090	COG1040	competence protein
XCCCN05v2_RS02105	COG0582	viral genome integration into host DNA
XCCCN05v2_RS02115	COG4774	siderophore transport
XCCCN05v2_RS02120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN05v2_RS02135	COG4206	TonB-dependent receptor
XCCCN05v2_RS02165	COG3264	Mechanosensitive ion channel
XCCCN05v2_RS02165	COG1511	domain protein
XCCCN05v2_RS02170	COG1368	sulfuric ester hydrolase activity
XCCCN05v2_RS02175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCCCN05v2_RS02180	COG2354	Protein conserved in bacteria
XCCCN05v2_RS02185	COG1649	PFAM Uncharacterised BCR, COG1649
XCCCN05v2_RS02195	COG0297	glycogen (starch) synthase activity
XCCCN05v2_RS02205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCCCN05v2_RS02230	COG0702	epimerase
XCCCN05v2_RS02265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN05v2_RS02270	COG2085	NADP oxidoreductase coenzyme F420-dependent
XCCCN05v2_RS02285	COG0513	Belongs to the DEAD box helicase family
XCCCN05v2_RS02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN05v2_RS02310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCCCN05v2_RS02325	COG3104	oligopeptide transport
XCCCN05v2_RS02345	COG2852	Protein conserved in bacteria
XCCCN05v2_RS02375	COG1320	monovalent cation:proton antiporter activity
XCCCN05v2_RS02380	COG2212	antiporter activity
XCCCN05v2_RS02390	COG0651	ATP synthesis coupled electron transport
XCCCN05v2_RS02395	COG1006	Multisubunit Na H antiporter MnhC subunit
XCCCN05v2_RS02400	COG2111	Na H antiporter
XCCCN05v2_RS02400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCCCN05v2_RS02415	COG3039	Transposase
XCCCN05v2_RS02480	COG0436	Aminotransferase
XCCCN05v2_RS02490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN05v2_RS02520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCCCN05v2_RS02625	COG2816	NAD+ diphosphatase activity
XCCCN05v2_RS02630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN05v2_RS02660	COG2814	Major facilitator Superfamily
XCCCN05v2_RS02670	COG1289	transmembrane transporter activity
XCCCN05v2_RS02675	COG0151	Belongs to the GarS family
XCCCN05v2_RS02690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN05v2_RS02695	COG2267	carboxylic ester hydrolase activity
XCCCN05v2_RS02700	COG0671	phosphoesterase, PA-phosphatase related
XCCCN05v2_RS02700	COG2453	phosphatase
XCCCN05v2_RS02725	COG4589	Belongs to the CDS family
XCCCN05v2_RS02740	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCCCN05v2_RS02775	COG0439	Biotin carboxylase
XCCCN05v2_RS02785	COG0511	ligase activity, forming carbon-carbon bonds
XCCCN05v2_RS02795	COG4232	protein-disulfide reductase activity
XCCCN05v2_RS02800	COG2356	endonuclease I
XCCCN05v2_RS02815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCCCN05v2_RS02825	COG1196	nuclear chromosome segregation
XCCCN05v2_RS02870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCCCN05v2_RS02895	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN05v2_RS02910	COG3712	iron ion homeostasis
XCCCN05v2_RS02950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN05v2_RS02975	COG2353	YceI-like domain
XCCCN05v2_RS03030	COG1802	Transcriptional regulator
XCCCN05v2_RS03160	COG0435	Glutathione S-transferase
XCCCN05v2_RS03220	COG2409	Drug exporters of the RND superfamily
XCCCN05v2_RS03230	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN05v2_RS03230	COG1506	peptidase
XCCCN05v2_RS03245	COG1959	2 iron, 2 sulfur cluster binding
XCCCN05v2_RS03285	COG0697	spore germination
XCCCN05v2_RS03300	COG4305	rare lipoprotein A
XCCCN05v2_RS03305	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN05v2_RS03320	COG1113	amino acid transport
XCCCN05v2_RS03380	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS03385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN05v2_RS03385	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN05v2_RS03390	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN05v2_RS03395	COG3706	GGDEF domain
XCCCN05v2_RS03410	COG3273	potassium ion transport
XCCCN05v2_RS03410	COG0471	metal ion transport
XCCCN05v2_RS03425	COG3275	phosphorelay sensor kinase activity
XCCCN05v2_RS03465	COG1505	serine-type exopeptidase activity
XCCCN05v2_RS03480	COG0436	Aminotransferase
XCCCN05v2_RS03490	COG2832	Protein of unknown function (DUF454)
XCCCN05v2_RS03560	COG2226	methyltransferase
XCCCN05v2_RS03565	COG5001	Diguanylate cyclase
XCCCN05v2_RS03565	COG3300	MHYT domain
XCCCN05v2_RS03570	COG0308	aminopeptidase N
XCCCN05v2_RS03605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCCCN05v2_RS03630	COG3284	Transcriptional regulator
XCCCN05v2_RS03635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN05v2_RS03640	COG1077	Cell shape determining protein MreB Mrl
XCCCN05v2_RS03650	COG1792	Involved in formation and maintenance of cell shape
XCCCN05v2_RS03665	COG0772	Belongs to the SEDS family
XCCCN05v2_RS03675	COG3039	Transposase
XCCCN05v2_RS03685	COG3039	Transposase
XCCCN05v2_RS03710	COG2951	lytic endotransglycosylase activity
XCCCN05v2_RS03715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCCCN05v2_RS03720	COG1686	Belongs to the peptidase S11 family
XCCCN05v2_RS03770	COG1051	belongs to the nudix hydrolase family
XCCCN05v2_RS03770	COG1056	cytidyltransferase-related domain
XCCCN05v2_RS03805	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCCCN05v2_RS03810	COG0673	inositol 2-dehydrogenase activity
XCCCN05v2_RS03815	COG2823	Periplasmic or secreted lipoprotein
XCCCN05v2_RS03820	COG4251	negative regulation of phosphorylation
XCCCN05v2_RS03825	COG0784	Response regulator, receiver
XCCCN05v2_RS03830	COG4191	Histidine kinase
XCCCN05v2_RS03835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCCCN05v2_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS03885	COG1459	type II secretion system
XCCCN05v2_RS03905	COG4795	General secretion pathway protein
XCCCN05v2_RS03930	COG2188	Transcriptional regulator
XCCCN05v2_RS03940	COG1609	Transcriptional regulator
XCCCN05v2_RS03945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN05v2_RS03950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCCCN05v2_RS04000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN05v2_RS04025	COG2205	protein histidine kinase activity
XCCCN05v2_RS04045	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS04065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCCCN05v2_RS04075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN05v2_RS04085	COG0697	spore germination
XCCCN05v2_RS04095	COG1307	EDD domain protein, DegV family
XCCCN05v2_RS04135	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN05v2_RS04155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN05v2_RS04175	COG0436	Aminotransferase
XCCCN05v2_RS04210	COG2211	Major facilitator Superfamily
XCCCN05v2_RS04215	COG1609	Transcriptional regulator
XCCCN05v2_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS04225	COG2851	Citrate transporter
XCCCN05v2_RS04240	COG0642	Histidine kinase
XCCCN05v2_RS04250	COG2197	response regulator
XCCCN05v2_RS04265	COG4191	Histidine kinase
XCCCN05v2_RS04305	COG1560	Kdo2-lipid A biosynthetic process
XCCCN05v2_RS04310	COG1519	Transferase
XCCCN05v2_RS04315	COG1538	Outer membrane efflux protein
XCCCN05v2_RS04320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCCCN05v2_RS04330	COG5001	Diguanylate cyclase
XCCCN05v2_RS04330	COG3300	MHYT domain
XCCCN05v2_RS04340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCCCN05v2_RS04350	COG2226	methyltransferase
XCCCN05v2_RS04385	COG0405	Gamma-glutamyltransferase
XCCCN05v2_RS04390	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS04395	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN05v2_RS04395	COG1506	peptidase
XCCCN05v2_RS04395	COG4946	Tricorn protease homolog
XCCCN05v2_RS04405	COG3710	Transcriptional regulator
XCCCN05v2_RS04425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCCCN05v2_RS04440	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCCCN05v2_RS04470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCCCN05v2_RS04480	COG3781	membrane
XCCCN05v2_RS04485	COG0671	phosphoesterase, PA-phosphatase related
XCCCN05v2_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS04505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN05v2_RS04510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCCCN05v2_RS04540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN05v2_RS04570	COG1773	rubredoxin
XCCCN05v2_RS04575	COG2912	Transglutaminase-like superfamily
XCCCN05v2_RS04595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCCCN05v2_RS04620	COG0006	proline dipeptidase activity
XCCCN05v2_RS04645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCCCN05v2_RS04655	COG0346	lactoylglutathione lyase activity
XCCCN05v2_RS04665	COG1561	YicC-like family, N-terminal region
XCCCN05v2_RS04680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN05v2_RS04690	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS04705	COG2271	Major facilitator Superfamily
XCCCN05v2_RS04720	COG2721	sulfolactate sulfo-lyase activity
XCCCN05v2_RS04730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCCCN05v2_RS04755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCCCN05v2_RS04785	COG0714	Associated with various cellular activities
XCCCN05v2_RS04805	COG2304	oxidoreductase activity
XCCCN05v2_RS04815	COG1301	dicarboxylic acid transport
XCCCN05v2_RS04820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCCCN05v2_RS04825	COG0596	Alpha beta hydrolase
XCCCN05v2_RS04830	COG4773	Receptor
XCCCN05v2_RS04835	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS04845	COG0739	heme binding
XCCCN05v2_RS04850	COG1376	ErfK ybiS ycfS ynhG family protein
XCCCN05v2_RS04895	COG4149	molybdate abc transporter
XCCCN05v2_RS04900	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCCCN05v2_RS04920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN05v2_RS04920	COG3453	Protein conserved in bacteria
XCCCN05v2_RS04935	COG3047	cAMP biosynthetic process
XCCCN05v2_RS04950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCCCN05v2_RS04980	COG0469	pyruvate kinase activity
XCCCN05v2_RS04985	COG3588	fructose-bisphosphate aldolase
XCCCN05v2_RS04990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCCCN05v2_RS05025	COG2198	Histidine kinase
XCCCN05v2_RS05025	COG2205	protein histidine kinase activity
XCCCN05v2_RS05025	COG0784	Response regulator, receiver
XCCCN05v2_RS05055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN05v2_RS05065	COG0529	Catalyzes the synthesis of activated sulfate
XCCCN05v2_RS05065	COG2895	sulfate adenylyltransferase (ATP) activity
XCCCN05v2_RS05070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN05v2_RS05075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN05v2_RS05080	COG0308	aminopeptidase N
XCCCN05v2_RS05090	COG1115	amino acid carrier protein
XCCCN05v2_RS05095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN05v2_RS05110	COG3039	Transposase
XCCCN05v2_RS05115	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN05v2_RS05120	COG3250	beta-galactosidase activity
XCCCN05v2_RS05135	COG1609	Transcriptional regulator
XCCCN05v2_RS05165	COG3273	potassium ion transport
XCCCN05v2_RS05165	COG0471	metal ion transport
XCCCN05v2_RS05195	COG0582	viral genome integration into host DNA
XCCCN05v2_RS05215	COG1396	sequence-specific DNA binding
XCCCN05v2_RS05220	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS05340	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS05370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCCCN05v2_RS05435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN05v2_RS05435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCCCN05v2_RS05445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN05v2_RS05450	COG0564	pseudouridine synthase activity
XCCCN05v2_RS05470	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS05490	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN05v2_RS05495	COG1877	trehalose-phosphatase activity
XCCCN05v2_RS05540	COG1116	anion transmembrane transporter activity
XCCCN05v2_RS05545	COG0542	response to heat
XCCCN05v2_RS05560	COG4206	TonB-dependent receptor
XCCCN05v2_RS05580	COG1797	cobyrinic acid a,c-diamide synthase activity
XCCCN05v2_RS05585	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN05v2_RS05615	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCCCN05v2_RS05640	COG0019	diaminopimelate decarboxylase activity
XCCCN05v2_RS05645	COG4264	IucA IucC family
XCCCN05v2_RS05650	COG2814	Major facilitator Superfamily
XCCCN05v2_RS05655	COG4264	IucA IucC family
XCCCN05v2_RS05665	COG4772	TonB-dependent receptor
XCCCN05v2_RS05675	COG4651	solute:proton antiporter activity
XCCCN05v2_RS05675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN05v2_RS05705	COG0488	(ABC) transporter
XCCCN05v2_RS05725	COG2755	lipolytic protein G-D-S-L family
XCCCN05v2_RS05725	COG0657	acetylesterase activity
XCCCN05v2_RS05745	COG0477	Major facilitator Superfamily
XCCCN05v2_RS05815	COG0824	Thioesterase
XCCCN05v2_RS05825	COG0848	biopolymer transport protein
XCCCN05v2_RS05840	COG2885	chlorophyll binding
XCCCN05v2_RS05850	COG0602	queuosine metabolic process
XCCCN05v2_RS05895	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS05920	COG1187	pseudouridine synthase activity
XCCCN05v2_RS05935	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN05v2_RS05940	COG0783	Belongs to the Dps family
XCCCN05v2_RS05945	COG1643	Atp-dependent helicase
XCCCN05v2_RS05995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN05v2_RS06005	COG1215	transferase activity, transferring glycosyl groups
XCCCN05v2_RS06010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCCCN05v2_RS06020	COG1199	ATP-dependent helicase activity
XCCCN05v2_RS06035	COG1397	ADP-ribosylglycohydrolase
XCCCN05v2_RS06045	COG0189	ligase activity
XCCCN05v2_RS06060	COG0835	chemotaxis
XCCCN05v2_RS06065	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS06070	COG2198	Histidine kinase
XCCCN05v2_RS06070	COG0643	Histidine kinase
XCCCN05v2_RS06070	COG0784	Response regulator, receiver
XCCCN05v2_RS06100	COG1595	DNA-templated transcription, initiation
XCCCN05v2_RS06105	COG2304	oxidoreductase activity
XCCCN05v2_RS06110	COG1446	asparaginase
XCCCN05v2_RS06165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN05v2_RS06170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN05v2_RS06185	COG3645	SOS response
XCCCN05v2_RS06225	COG3537	Alpha-1,2-mannosidase
XCCCN05v2_RS06235	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN05v2_RS06245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCCCN05v2_RS06250	COG1388	LysM domain
XCCCN05v2_RS06250	COG3858	chitin binding
XCCCN05v2_RS06275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCCCN05v2_RS06285	COG0494	nUDIX hydrolase
XCCCN05v2_RS06290	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCCCN05v2_RS06295	COG3956	TIGRFAM MazG family protein
XCCCN05v2_RS06305	COG0330	HflC and HflK could
XCCCN05v2_RS06355	COG1960	acyl-CoA dehydrogenase activity
XCCCN05v2_RS06365	COG1309	transcriptional regulator
XCCCN05v2_RS06370	COG4771	TonB-dependent receptor
XCCCN05v2_RS06380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCCCN05v2_RS06390	COG0463	Glycosyl transferase, family 2
XCCCN05v2_RS06395	COG0516	GMP reductase activity
XCCCN05v2_RS06395	COG0517	IMP dehydrogenase activity
XCCCN05v2_RS06400	COG2982	Protein involved in outer membrane biogenesis
XCCCN05v2_RS06405	COG1272	protein, Hemolysin III
XCCCN05v2_RS06420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN05v2_RS06425	COG0626	cystathionine gamma-synthase activity
XCCCN05v2_RS06430	COG0460	homoserine dehydrogenase
XCCCN05v2_RS06430	COG0527	aspartate kinase activity
XCCCN05v2_RS06445	COG1760	l-serine dehydratase
XCCCN05v2_RS06465	COG2353	YceI-like domain
XCCCN05v2_RS06485	COG0477	Major facilitator Superfamily
XCCCN05v2_RS06525	COG1842	Phage shock protein A
XCCCN05v2_RS06550	COG0754	glutathionylspermidine amidase activity
XCCCN05v2_RS06565	COG2814	Major facilitator Superfamily
XCCCN05v2_RS06635	COG0531	amino acid
XCCCN05v2_RS06640	COG2197	response regulator
XCCCN05v2_RS06660	COG1113	amino acid transport
XCCCN05v2_RS06665	COG1271	oxidase subunit
XCCCN05v2_RS06670	COG1294	oxidase, subunit
XCCCN05v2_RS06680	COG2239	Acts as a magnesium transporter
XCCCN05v2_RS06685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN05v2_RS06690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN05v2_RS06710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN05v2_RS06725	COG1137	ATPase activity
XCCCN05v2_RS06740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCCCN05v2_RS06750	COG0271	Belongs to the BolA IbaG family
XCCCN05v2_RS06775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCCCN05v2_RS06795	COG0628	permease
XCCCN05v2_RS06805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN05v2_RS06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN05v2_RS06825	COG1555	photosystem II stabilization
XCCCN05v2_RS06870	COG4774	siderophore transport
XCCCN05v2_RS06875	COG2146	nitrite reductase [NAD(P)H] activity
XCCCN05v2_RS06885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN05v2_RS06890	COG0719	Fe-S assembly protein
XCCCN05v2_RS06895	COG0396	ATPase activity
XCCCN05v2_RS06900	COG0719	Fe-S assembly protein
XCCCN05v2_RS06950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCCCN05v2_RS06980	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN05v2_RS06985	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCCCN05v2_RS07005	COG1764	response to oxidative stress
XCCCN05v2_RS07015	COG0384	phenazine biosynthesis protein PhzF
XCCCN05v2_RS07020	COG0384	phenazine biosynthesis protein PhzF
XCCCN05v2_RS07025	COG0527	aspartate kinase activity
XCCCN05v2_RS07050	COG0142	geranyltranstransferase activity
XCCCN05v2_RS07055	COG0629	single-stranded DNA binding
XCCCN05v2_RS07065	COG1401	restriction endodeoxyribonuclease activity
XCCCN05v2_RS07080	COG2203	Gaf domain
XCCCN05v2_RS07080	COG4251	negative regulation of phosphorylation
XCCCN05v2_RS07080	COG5001	Diguanylate cyclase
XCCCN05v2_RS07080	COG3706	GGDEF domain
XCCCN05v2_RS07085	COG0604	alcohol dehydrogenase
XCCCN05v2_RS07090	COG2080	2 iron, 2 sulfur cluster binding
XCCCN05v2_RS07095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN05v2_RS07100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN05v2_RS07105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCCCN05v2_RS07140	COG2879	small protein
XCCCN05v2_RS07145	COG1966	Carbon starvation protein
XCCCN05v2_RS07150	COG1741	Belongs to the pirin family
XCCCN05v2_RS07170	COG1741	Belongs to the pirin family
XCCCN05v2_RS07190	COG3590	peptidase
XCCCN05v2_RS07195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS07205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN05v2_RS07210	COG2199	diguanylate cyclase activity
XCCCN05v2_RS07210	COG2202	Pas domain
XCCCN05v2_RS07210	COG2200	EAL domain
XCCCN05v2_RS07215	COG0835	chemotaxis
XCCCN05v2_RS07220	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS07225	COG2198	Histidine kinase
XCCCN05v2_RS07225	COG0643	Histidine kinase
XCCCN05v2_RS07235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCCCN05v2_RS07250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCCCN05v2_RS07255	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS07260	COG2205	protein histidine kinase activity
XCCCN05v2_RS07265	COG4452	Inner membrane protein CreD
XCCCN05v2_RS07300	COG0735	belongs to the Fur family
XCCCN05v2_RS07320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN05v2_RS07330	COG1309	transcriptional regulator
XCCCN05v2_RS07335	COG0667	Aldo Keto reductase
XCCCN05v2_RS07350	COG2207	Transcriptional regulator
XCCCN05v2_RS07370	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS07375	COG2814	Major facilitator Superfamily
XCCCN05v2_RS07395	COG1404	Belongs to the peptidase S8 family
XCCCN05v2_RS07405	COG3383	formate dehydrogenase (NAD+) activity
XCCCN05v2_RS07415	COG1271	oxidase subunit
XCCCN05v2_RS07420	COG1294	oxidase, subunit
XCCCN05v2_RS07515	COG5002	protein histidine kinase activity
XCCCN05v2_RS07515	COG5001	Diguanylate cyclase
XCCCN05v2_RS07520	COG1187	pseudouridine synthase activity
XCCCN05v2_RS07545	COG0475	glutathione-regulated potassium exporter activity
XCCCN05v2_RS07550	COG1132	(ABC) transporter
XCCCN05v2_RS07605	COG2155	Conserved Protein
XCCCN05v2_RS07615	COG3118	belongs to the thioredoxin family
XCCCN05v2_RS07640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCCCN05v2_RS07670	COG2968	Membrane
XCCCN05v2_RS07685	COG3164	Protein of unknown function
XCCCN05v2_RS07695	COG0312	modulator of DNA gyrase
XCCCN05v2_RS07705	COG0312	modulator of DNA gyrase
XCCCN05v2_RS07725	COG0142	geranyltranstransferase activity
XCCCN05v2_RS07740	COG1785	Belongs to the alkaline phosphatase family
XCCCN05v2_RS07745	COG1301	dicarboxylic acid transport
XCCCN05v2_RS07750	COG4106	trans-aconitate 2-methyltransferase activity
XCCCN05v2_RS07765	COG4191	Histidine kinase
XCCCN05v2_RS07770	COG3284	Transcriptional regulator
XCCCN05v2_RS07800	COG0791	NLP P60 protein
XCCCN05v2_RS07805	COG0791	NLP P60 protein
XCCCN05v2_RS07810	COG1047	Peptidyl-prolyl cis-trans
XCCCN05v2_RS07815	COG2311	Membrane
XCCCN05v2_RS07820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN05v2_RS07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN05v2_RS07845	COG3590	peptidase
XCCCN05v2_RS07850	COG3590	peptidase
XCCCN05v2_RS07870	COG0489	protein tyrosine kinase activity
XCCCN05v2_RS07875	COG0717	Belongs to the dCTP deaminase family
XCCCN05v2_RS07910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN05v2_RS07925	COG0494	nUDIX hydrolase
XCCCN05v2_RS07940	COG0433	COG0433 Predicted ATPase
XCCCN05v2_RS07970	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN05v2_RS07985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCCCN05v2_RS07990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCCCN05v2_RS08080	COG4221	oxidoreductase activity
XCCCN05v2_RS08100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCCCN05v2_RS08120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCCCN05v2_RS08125	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCCCN05v2_RS08165	COG1007	ATP synthesis coupled electron transport
XCCCN05v2_RS08180	COG0195	Participates in both transcription termination and antitermination
XCCCN05v2_RS08240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN05v2_RS08250	COG2095	MarC family integral membrane protein
XCCCN05v2_RS08260	COG1611	Belongs to the LOG family
XCCCN05v2_RS08265	COG4969	Belongs to the N-Me-Phe pilin family
XCCCN05v2_RS08320	COG3505	Type IV secretory pathway VirD4
XCCCN05v2_RS08340	COG2948	multi-organism process
XCCCN05v2_RS08360	COG3702	type iv secretory pathway
XCCCN05v2_RS08380	COG0366	Alpha amylase catalytic
XCCCN05v2_RS08400	COG1082	Xylose isomerase domain protein TIM barrel
XCCCN05v2_RS08430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCCCN05v2_RS08500	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS08505	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS08510	COG2244	polysaccharide biosynthetic process
XCCCN05v2_RS08540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN05v2_RS08545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN05v2_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN05v2_RS08610	COG0322	excinuclease ABC activity
XCCCN05v2_RS08630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN05v2_RS08640	COG4191	Histidine kinase
XCCCN05v2_RS08640	COG0784	Response regulator, receiver
XCCCN05v2_RS08660	COG0552	protein localization to endoplasmic reticulum
XCCCN05v2_RS08670	COG3938	Belongs to the proline racemase family
XCCCN05v2_RS08690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN05v2_RS08700	COG0006	proline dipeptidase activity
XCCCN05v2_RS08720	COG0531	amino acid
XCCCN05v2_RS08755	COG4206	TonB-dependent receptor
XCCCN05v2_RS08765	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN05v2_RS08770	COG1506	peptidase
XCCCN05v2_RS08770	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN05v2_RS08780	COG4206	TonB-dependent receptor
XCCCN05v2_RS08795	COG0326	Molecular chaperone. Has ATPase activity
XCCCN05v2_RS08800	COG0742	ribosomal rna small subunit methyltransferase
XCCCN05v2_RS08820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCCCN05v2_RS08825	COG0405	Gamma-glutamyltransferase
XCCCN05v2_RS08830	COG3291	Pkd domain containing protein
XCCCN05v2_RS08860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCCCN05v2_RS08880	COG1862	Preprotein translocase
XCCCN05v2_RS08890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCCCN05v2_RS08905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN05v2_RS08905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN05v2_RS08910	COG1105	Belongs to the carbohydrate kinase PfkB family
XCCCN05v2_RS08915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN05v2_RS08915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN05v2_RS08920	COG1609	Transcriptional regulator
XCCCN05v2_RS08930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN05v2_RS08935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN05v2_RS08945	COG2902	Dehydrogenase
XCCCN05v2_RS08950	COG2207	Transcriptional regulator
XCCCN05v2_RS08950	COG1609	Transcriptional regulator
XCCCN05v2_RS08955	COG1335	isochorismatase
XCCCN05v2_RS08960	COG0477	Major facilitator Superfamily
XCCCN05v2_RS08975	COG2733	membrane
XCCCN05v2_RS08985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCCCN05v2_RS08990	COG2223	nitrite transmembrane transporter activity
XCCCN05v2_RS09000	COG0243	molybdopterin cofactor binding
XCCCN05v2_RS09010	COG0477	Major facilitator Superfamily
XCCCN05v2_RS09015	COG2703	oxygen carrier activity
XCCCN05v2_RS09025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN05v2_RS09030	COG0174	glutamine synthetase
XCCCN05v2_RS09035	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCCCN05v2_RS09070	COG3842	ATPase activity
XCCCN05v2_RS09080	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCCCN05v2_RS09085	COG1177	transmembrane transport
XCCCN05v2_RS09095	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN05v2_RS09110	COG4535	Mg2 and Co2 transporter CorC
XCCCN05v2_RS09130	COG1702	phosphate starvation-inducible protein PhoH
XCCCN05v2_RS09150	COG0741	lytic transglycosylase activity
XCCCN05v2_RS09155	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN05v2_RS09160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCCCN05v2_RS09165	COG2857	Cytochrome c1
XCCCN05v2_RS09170	COG0625	glutathione transferase activity
XCCCN05v2_RS09175	COG2969	positive regulation of protein catabolic process
XCCCN05v2_RS09190	COG1201	RNA secondary structure unwinding
XCCCN05v2_RS09200	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS09205	COG0835	chemotaxis
XCCCN05v2_RS09245	COG0582	viral genome integration into host DNA
XCCCN05v2_RS09275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN05v2_RS09290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCCCN05v2_RS09295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCCCN05v2_RS09295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN05v2_RS09305	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN05v2_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS09345	COG3300	MHYT domain
XCCCN05v2_RS09345	COG5001	Diguanylate cyclase
XCCCN05v2_RS09350	COG2081	HI0933 family
XCCCN05v2_RS09355	COG4681	YaeQ
XCCCN05v2_RS09395	COG0513	Belongs to the DEAD box helicase family
XCCCN05v2_RS09400	COG0488	(ABC) transporter
XCCCN05v2_RS09415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN05v2_RS09420	COG0483	inositol monophosphate 1-phosphatase activity
XCCCN05v2_RS09435	COG3300	MHYT domain
XCCCN05v2_RS09435	COG5001	Diguanylate cyclase
XCCCN05v2_RS09440	COG1509	lysine 2,3-aminomutase activity
XCCCN05v2_RS09455	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN05v2_RS09505	COG4302	ethanolamine ammonia-lyase activity
XCCCN05v2_RS09525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCCCN05v2_RS09550	COG2166	iron-sulfur cluster assembly
XCCCN05v2_RS09565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCCCN05v2_RS09575	COG0137	argininosuccinate synthase activity
XCCCN05v2_RS09580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN05v2_RS09585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCCCN05v2_RS09615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XCCCN05v2_RS09655	COG1294	oxidase, subunit
XCCCN05v2_RS09665	COG4988	ABC transporter
XCCCN05v2_RS09670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCCCN05v2_RS09735	COG0436	Aminotransferase
XCCCN05v2_RS09760	COG1187	pseudouridine synthase activity
XCCCN05v2_RS09765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCCCN05v2_RS09770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCCCN05v2_RS09775	COG2350	Protein conserved in bacteria
XCCCN05v2_RS09810	COG0395	ABC-type sugar transport system, permease component
XCCCN05v2_RS09835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN05v2_RS09840	COG2957	Belongs to the agmatine deiminase family
XCCCN05v2_RS09860	COG0539	negative regulation of cytoplasmic translation
XCCCN05v2_RS09875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCCCN05v2_RS09890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCCCN05v2_RS09895	COG0475	glutathione-regulated potassium exporter activity
XCCCN05v2_RS09895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN05v2_RS09920	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN05v2_RS09945	COG2197	response regulator
XCCCN05v2_RS09960	COG1335	isochorismatase
XCCCN05v2_RS09975	COG2814	Major facilitator Superfamily
XCCCN05v2_RS09990	COG1914	H( )-stimulated, divalent metal cation uptake system
XCCCN05v2_RS10010	COG0668	transmembrane transport
XCCCN05v2_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS10045	COG1183	phosphatidylcholine synthase activity
XCCCN05v2_RS10055	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCCCN05v2_RS10070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN05v2_RS10070	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN05v2_RS10080	COG2183	response to ionizing radiation
XCCCN05v2_RS10085	COG5001	Diguanylate cyclase
XCCCN05v2_RS10155	COG0800	Aldolase
XCCCN05v2_RS10160	COG0129	dihydroxy-acid dehydratase activity
XCCCN05v2_RS10165	COG0363	glucosamine-6-phosphate deaminase activity
XCCCN05v2_RS10175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN05v2_RS10185	COG0354	folic acid binding
XCCCN05v2_RS10200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCCCN05v2_RS10205	COG1053	succinate dehydrogenase
XCCCN05v2_RS10215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCCCN05v2_RS10230	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCCCN05v2_RS10250	COG0811	peptide transport
XCCCN05v2_RS10275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCCCN05v2_RS10290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN05v2_RS10320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCCCN05v2_RS10355	COG1530	ribonuclease E activity
XCCCN05v2_RS10365	COG0428	transporter
XCCCN05v2_RS10505	COG3279	Response regulator of the LytR AlgR family
XCCCN05v2_RS10515	COG3459	Glycosyltransferase 36 associated
XCCCN05v2_RS10525	COG0784	Response regulator, receiver
XCCCN05v2_RS10525	COG4191	Histidine kinase
XCCCN05v2_RS10545	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS10555	COG1238	metal cluster binding
XCCCN05v2_RS10585	COG1733	regulation of RNA biosynthetic process
XCCCN05v2_RS10600	COG1999	signal sequence binding
XCCCN05v2_RS10615	COG3590	peptidase
XCCCN05v2_RS10685	COG5001	Diguanylate cyclase
XCCCN05v2_RS10695	COG2201	protein-glutamate methylesterase activity
XCCCN05v2_RS10700	COG3685	Protein conserved in bacteria
XCCCN05v2_RS10715	COG0579	oxidoreductase
XCCCN05v2_RS10725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN05v2_RS10735	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCCCN05v2_RS10755	COG0243	molybdopterin cofactor binding
XCCCN05v2_RS10765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCCCN05v2_RS10770	COG2223	nitrite transmembrane transporter activity
XCCCN05v2_RS10775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCCCN05v2_RS10785	COG1648	precorrin-2 dehydrogenase activity
XCCCN05v2_RS10785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCCCN05v2_RS10795	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN05v2_RS10800	COG0303	'Molybdopterin
XCCCN05v2_RS10810	COG0708	Exodeoxyribonuclease III
XCCCN05v2_RS10835	COG2124	cytochrome p450
XCCCN05v2_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS10855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCCCN05v2_RS10870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN05v2_RS10905	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS10905	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCCCN05v2_RS10910	COG0183	Belongs to the thiolase family
XCCCN05v2_RS10915	COG0038	chloride channel
XCCCN05v2_RS10920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCCCN05v2_RS10940	COG1674	ftsk spoiiie
XCCCN05v2_RS10945	COG0492	ferredoxin-NADP+ reductase activity
XCCCN05v2_RS10965	COG0542	response to heat
XCCCN05v2_RS10985	COG2915	High frequency lysogenization protein hflD homolog
XCCCN05v2_RS11020	COG4191	Histidine kinase
XCCCN05v2_RS11040	COG0784	Response regulator, receiver
XCCCN05v2_RS11040	COG0835	chemotaxis
XCCCN05v2_RS11050	COG1558	bacterial-type flagellum-dependent cell motility
XCCCN05v2_RS11055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCCCN05v2_RS11065	COG4787	bacterial-type flagellum-dependent cell motility
XCCCN05v2_RS11085	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCCCN05v2_RS11085	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCCCN05v2_RS11095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN05v2_RS11100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN05v2_RS11105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCCCN05v2_RS11135	COG2201	protein-glutamate methylesterase activity
XCCCN05v2_RS11165	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS11165	COG1216	Glycosyl transferase, family 2
XCCCN05v2_RS11170	COG1677	Flagellar hook-basal body complex protein FliE
XCCCN05v2_RS11240	COG1684	flagellar biosynthetic protein fliR
XCCCN05v2_RS11295	COG2198	Histidine kinase
XCCCN05v2_RS11295	COG0784	Response regulator, receiver
XCCCN05v2_RS11295	COG0643	Histidine kinase
XCCCN05v2_RS11365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCCCN05v2_RS11370	COG1360	Flagellar Motor Protein
XCCCN05v2_RS11375	COG1192	Involved in chromosome partitioning
XCCCN05v2_RS11380	COG0835	chemotaxis
XCCCN05v2_RS11390	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS11400	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11410	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11415	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11420	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11425	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11430	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11435	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11445	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11455	COG0835	chemotaxis
XCCCN05v2_RS11465	COG0840	transmembrane signaling receptor activity
XCCCN05v2_RS11490	COG2267	carboxylic ester hydrolase activity
XCCCN05v2_RS11520	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN05v2_RS11525	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS11530	COG2205	protein histidine kinase activity
XCCCN05v2_RS11530	COG2198	Histidine kinase
XCCCN05v2_RS11530	COG0784	Response regulator, receiver
XCCCN05v2_RS11535	COG2198	Histidine kinase
XCCCN05v2_RS11535	COG0784	Response regulator, receiver
XCCCN05v2_RS11535	COG2205	protein histidine kinase activity
XCCCN05v2_RS11555	COG3279	Response regulator of the LytR AlgR family
XCCCN05v2_RS11575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCCCN05v2_RS11585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN05v2_RS11590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCCCN05v2_RS11600	COG0505	Belongs to the CarA family
XCCCN05v2_RS11610	COG2258	MOSC domain
XCCCN05v2_RS11615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN05v2_RS11640	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS11675	COG0277	FAD linked oxidase domain protein
XCCCN05v2_RS11680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN05v2_RS11695	COG0531	amino acid
XCCCN05v2_RS11700	COG0531	amino acid
XCCCN05v2_RS11730	COG0140	phosphoribosyl-ATP diphosphatase activity
XCCCN05v2_RS11730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCCCN05v2_RS11750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCCCN05v2_RS11750	COG0131	Imidazoleglycerol-phosphate dehydratase
XCCCN05v2_RS11765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XCCCN05v2_RS11780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN05v2_RS11790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCCCN05v2_RS11800	COG0083	homoserine kinase activity
XCCCN05v2_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN05v2_RS11870	COG0697	spore germination
XCCCN05v2_RS11875	COG1794	racemase activity, acting on amino acids and derivatives
XCCCN05v2_RS11885	COG0671	phosphoesterase, PA-phosphatase related
XCCCN05v2_RS11900	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCCCN05v2_RS11905	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN05v2_RS11910	COG3706	GGDEF domain
XCCCN05v2_RS11910	COG4251	negative regulation of phosphorylation
XCCCN05v2_RS11910	COG5001	Diguanylate cyclase
XCCCN05v2_RS11910	COG2203	Gaf domain
XCCCN05v2_RS11920	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN05v2_RS11975	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN05v2_RS11995	COG0477	Major facilitator Superfamily
XCCCN05v2_RS12005	COG1070	Carbohydrate kinase
XCCCN05v2_RS12015	COG1501	Belongs to the glycosyl hydrolase 31 family
XCCCN05v2_RS12055	COG0800	Aldolase
XCCCN05v2_RS12070	COG3734	2-keto-3-deoxy-galactonokinase
XCCCN05v2_RS12075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCCCN05v2_RS12085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN05v2_RS12100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCCCN05v2_RS12105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCCCN05v2_RS12115	COG0351	phosphomethylpyrimidine kinase
XCCCN05v2_RS12115	COG0352	thiamine-phosphate diphosphorylase activity
XCCCN05v2_RS12140	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS12145	COG1741	Belongs to the pirin family
XCCCN05v2_RS12180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN05v2_RS12190	COG4771	TonB-dependent receptor
XCCCN05v2_RS12200	COG1546	Belongs to the CinA family
XCCCN05v2_RS12205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCCCN05v2_RS12220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCCCN05v2_RS12225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCCCN05v2_RS12235	COG1534	Rna-binding protein
XCCCN05v2_RS12250	COG1238	metal cluster binding
XCCCN05v2_RS12265	COG2840	Smr protein MutS2
XCCCN05v2_RS12325	COG2134	cdp-diacylglycerol pyrophosphatase
XCCCN05v2_RS12350	COG1253	flavin adenine dinucleotide binding
XCCCN05v2_RS12365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCCCN05v2_RS12370	COG0477	Major facilitator Superfamily
XCCCN05v2_RS12395	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS12400	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS12405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN05v2_RS12435	COG2244	polysaccharide biosynthetic process
XCCCN05v2_RS12450	COG3038	cytochrome b561
XCCCN05v2_RS12485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN05v2_RS12505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN05v2_RS12520	COG4191	Histidine kinase
XCCCN05v2_RS12520	COG0784	Response regulator, receiver
XCCCN05v2_RS12525	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCCCN05v2_RS12575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCCCN05v2_RS12625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN05v2_RS12650	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS12665	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCCCN05v2_RS12675	COG0077	Prephenate dehydratase
XCCCN05v2_RS12675	COG1605	Chorismate mutase
XCCCN05v2_RS12685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCCCN05v2_RS12740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCCCN05v2_RS12750	COG4993	Dehydrogenase
XCCCN05v2_RS12770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCCCN05v2_RS12820	COG0316	Belongs to the HesB IscA family
XCCCN05v2_RS12850	COG0288	reversible hydration of carbon dioxide
XCCCN05v2_RS12875	COG2925	Exonuclease
XCCCN05v2_RS12890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCCCN05v2_RS12910	COG0488	(ABC) transporter
XCCCN05v2_RS12915	COG2264	protein methyltransferase activity
XCCCN05v2_RS12950	COG0494	nUDIX hydrolase
XCCCN05v2_RS12960	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS12970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCCCN05v2_RS12975	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN05v2_RS13000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCCCN05v2_RS13005	COG0573	inorganic phosphate transmembrane transporter activity
XCCCN05v2_RS13010	COG0581	inorganic phosphate transmembrane transporter activity
XCCCN05v2_RS13020	COG0704	Plays a role in the regulation of phosphate uptake
XCCCN05v2_RS13050	COG0557	exoribonuclease II activity
XCCCN05v2_RS13065	COG1960	acyl-CoA dehydrogenase activity
XCCCN05v2_RS13070	COG2226	methyltransferase
XCCCN05v2_RS13075	COG0646	methionine synthase
XCCCN05v2_RS13075	COG1410	methionine synthase
XCCCN05v2_RS13080	COG0646	methionine synthase
XCCCN05v2_RS13080	COG1410	methionine synthase
XCCCN05v2_RS13090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN05v2_RS13100	COG1609	Transcriptional regulator
XCCCN05v2_RS13140	COG0386	Belongs to the glutathione peroxidase family
XCCCN05v2_RS13150	COG1725	Transcriptional regulator
XCCCN05v2_RS13155	COG1131	(ABC) transporter
XCCCN05v2_RS13200	COG2850	peptidyl-arginine hydroxylation
XCCCN05v2_RS13235	COG1132	(ABC) transporter
XCCCN05v2_RS13240	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS13245	COG2274	protein secretion by the type I secretion system
XCCCN05v2_RS13270	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCCCN05v2_RS13290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCCCN05v2_RS13295	COG1420	regulation of RNA biosynthetic process
XCCCN05v2_RS13300	COG0497	DNA recombination
XCCCN05v2_RS13310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN05v2_RS13405	COG3706	GGDEF domain
XCCCN05v2_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS13435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN05v2_RS13445	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS13455	COG0415	Belongs to the DNA photolyase family
XCCCN05v2_RS13460	COG0305	Participates in initiation and elongation during chromosome replication
XCCCN05v2_RS13470	COG0367	asparagine synthase
XCCCN05v2_RS13485	COG1960	acyl-CoA dehydrogenase activity
XCCCN05v2_RS13500	COG0084	hydrolase, TatD family'
XCCCN05v2_RS13505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCCCN05v2_RS13565	COG0386	Belongs to the glutathione peroxidase family
XCCCN05v2_RS13570	COG0339	signal peptide processing
XCCCN05v2_RS13605	COG3104	oligopeptide transport
XCCCN05v2_RS13635	COG2814	Major facilitator Superfamily
XCCCN05v2_RS13640	COG1566	PFAM secretion protein HlyD family protein
XCCCN05v2_RS13680	COG4774	siderophore transport
XCCCN05v2_RS13690	COG0367	asparagine synthase
XCCCN05v2_RS13705	COG1393	Belongs to the ArsC family
XCCCN05v2_RS13775	COG0528	UMP kinase activity
XCCCN05v2_RS13785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCCCN05v2_RS13790	COG0575	Belongs to the CDS family
XCCCN05v2_RS13800	COG0750	zinc metalloprotease
XCCCN05v2_RS13855	COG1981	membrane
XCCCN05v2_RS13880	COG1695	Transcriptional regulator
XCCCN05v2_RS13905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN05v2_RS13915	COG2040	homocysteine
XCCCN05v2_RS13920	COG0833	amino acid
XCCCN05v2_RS13925	COG0346	lactoylglutathione lyase activity
XCCCN05v2_RS13950	COG2878	Part of a membrane complex involved in electron transport
XCCCN05v2_RS13965	COG1595	DNA-templated transcription, initiation
XCCCN05v2_RS13990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN05v2_RS14005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN05v2_RS14010	COG0251	oxidation-reduction process
XCCCN05v2_RS14020	COG0392	lysyltransferase activity
XCCCN05v2_RS14020	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCCCN05v2_RS14055	COG2814	Major facilitator Superfamily
XCCCN05v2_RS14060	COG1902	pentaerythritol trinitrate reductase activity
XCCCN05v2_RS14080	COG3039	Transposase
XCCCN05v2_RS14090	COG2824	Alkylphosphonate utilization operon protein PhnA
XCCCN05v2_RS14100	COG1047	Peptidyl-prolyl cis-trans
XCCCN05v2_RS14145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCCCN05v2_RS14155	COG5487	UPF0391 membrane protein
XCCCN05v2_RS14160	COG1451	nucleotide metabolic process
XCCCN05v2_RS14180	COG0183	Belongs to the thiolase family
XCCCN05v2_RS14215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCCCN05v2_RS14215	COG1793	dna ligase
XCCCN05v2_RS14225	COG1793	dna ligase
XCCCN05v2_RS14230	COG1201	RNA secondary structure unwinding
XCCCN05v2_RS14240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN05v2_RS14245	COG1278	Cold shock
XCCCN05v2_RS14250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCCCN05v2_RS14255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCCCN05v2_RS14265	COG3046	protein related to deoxyribodipyrimidine photolyase
XCCCN05v2_RS14270	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XCCCN05v2_RS14275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCCCN05v2_RS14280	COG2954	triphosphatase activity
XCCCN05v2_RS14330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN05v2_RS14365	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS14370	COG1960	acyl-CoA dehydrogenase activity
XCCCN05v2_RS14380	COG1396	sequence-specific DNA binding
XCCCN05v2_RS14380	COG3800	Transcriptional regulator
XCCCN05v2_RS14390	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCCCN05v2_RS14395	COG3250	beta-galactosidase activity
XCCCN05v2_RS14440	COG3039	Transposase
XCCCN05v2_RS14530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCCCN05v2_RS14585	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN05v2_RS14605	COG1309	transcriptional regulator
XCCCN05v2_RS14610	COG0436	Aminotransferase
XCCCN05v2_RS14620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN05v2_RS14635	COG3483	tryptophan 2,3-dioxygenase activity
XCCCN05v2_RS14645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCCCN05v2_RS14665	COG0534	Mate efflux family protein
XCCCN05v2_RS14695	COG2070	2-Nitropropane dioxygenase
XCCCN05v2_RS14710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCCCN05v2_RS14715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN05v2_RS14725	COG3534	alpha-L-arabinofuranosidase
XCCCN05v2_RS14755	COG0784	Response regulator, receiver
XCCCN05v2_RS14755	COG4191	Histidine kinase
XCCCN05v2_RS14760	COG2205	protein histidine kinase activity
XCCCN05v2_RS14760	COG3437	response regulator, receiver
XCCCN05v2_RS14760	COG3850	Histidine kinase
XCCCN05v2_RS14760	COG4999	Histidine kinase
XCCCN05v2_RS14765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN05v2_RS14775	COG2205	protein histidine kinase activity
XCCCN05v2_RS14780	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCCCN05v2_RS14795	COG4771	TonB-dependent receptor
XCCCN05v2_RS14820	COG2172	sigma factor antagonist activity
XCCCN05v2_RS14825	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN05v2_RS14830	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN05v2_RS14835	COG1902	pentaerythritol trinitrate reductase activity
XCCCN05v2_RS14845	COG0326	Molecular chaperone. Has ATPase activity
XCCCN05v2_RS14850	COG2207	Transcriptional regulator
XCCCN05v2_RS14860	COG3152	Membrane
XCCCN05v2_RS14875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCCCN05v2_RS14880	COG1845	cytochrome c oxidase, subunit III
XCCCN05v2_RS14885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCCCN05v2_RS14915	COG0196	riboflavin kinase activity
XCCCN05v2_RS14945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCCCN05v2_RS14950	COG0824	Thioesterase
XCCCN05v2_RS14955	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS14960	COG1946	Acyl-CoA thioesterase
XCCCN05v2_RS15035	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN05v2_RS15065	COG2197	response regulator
XCCCN05v2_RS15085	COG2894	cell division
XCCCN05v2_RS15100	COG5002	protein histidine kinase activity
XCCCN05v2_RS15105	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS15140	COG2814	Major facilitator Superfamily
XCCCN05v2_RS15160	COG0656	L-ascorbic acid biosynthetic process
XCCCN05v2_RS15165	COG0753	catalase activity
XCCCN05v2_RS15180	COG1917	Cupin 2, conserved barrel domain protein
XCCCN05v2_RS15180	COG2207	Transcriptional regulator
XCCCN05v2_RS15200	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN05v2_RS15200	COG1506	peptidase
XCCCN05v2_RS15210	COG1297	OPT oligopeptide transporter protein
XCCCN05v2_RS15235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN05v2_RS15265	COG2080	2 iron, 2 sulfur cluster binding
XCCCN05v2_RS15270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN05v2_RS15275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN05v2_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS15325	COG3537	Alpha-1,2-mannosidase
XCCCN05v2_RS15335	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS15340	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN05v2_RS15350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN05v2_RS15430	COG0308	aminopeptidase N
XCCCN05v2_RS15445	COG0330	HflC and HflK could
XCCCN05v2_RS15450	COG0330	HflC and HflK could
XCCCN05v2_RS15470	COG0678	peroxiredoxin activity
XCCCN05v2_RS15480	COG4953	penicillin-binding protein 1C
XCCCN05v2_RS15505	COG2373	Large extracellular alpha-helical protein
XCCCN05v2_RS15535	COG3609	addiction module antidote protein, CC2985 family
XCCCN05v2_RS15555	COG3829	transcription factor binding
XCCCN05v2_RS15600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCCCN05v2_RS15605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCCCN05v2_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS15625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCCCN05v2_RS15630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN05v2_RS15640	COG1399	metal-binding, possibly nucleic acid-binding protein
XCCCN05v2_RS15675	COG0714	Associated with various cellular activities
XCCCN05v2_RS15695	COG0537	adenosine 5'-monophosphoramidase activity
XCCCN05v2_RS15725	COG0314	molybdopterin synthase activity
XCCCN05v2_RS15730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCCCN05v2_RS15750	COG1234	tRNA 3'-trailer cleavage
XCCCN05v2_RS15760	COG0859	PFAM glycosyl transferase family 9
XCCCN05v2_RS15775	COG0631	protein serine/threonine phosphatase activity
XCCCN05v2_RS15780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCCCN05v2_RS15880	COG0473	3-isopropylmalate dehydrogenase activity
XCCCN05v2_RS15895	COG4783	chaperone-mediated protein folding
XCCCN05v2_RS15900	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS15910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCCCN05v2_RS15920	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS15925	COG0671	phosphoesterase, PA-phosphatase related
XCCCN05v2_RS15930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCCCN05v2_RS15940	COG3291	Pkd domain containing protein
XCCCN05v2_RS15945	COG2833	Protein of unknown function (DUF455)
XCCCN05v2_RS15965	COG0285	dihydrofolate synthase activity
XCCCN05v2_RS15980	COG0406	alpha-ribazole phosphatase activity
XCCCN05v2_RS16005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCCCN05v2_RS16010	COG4208	sulfate ABC transporter
XCCCN05v2_RS16015	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCCCN05v2_RS16020	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCCCN05v2_RS16055	COG1902	pentaerythritol trinitrate reductase activity
XCCCN05v2_RS16055	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCCCN05v2_RS16075	COG0625	glutathione transferase activity
XCCCN05v2_RS16085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCCCN05v2_RS16090	COG1217	gtp-binding protein TYPA
XCCCN05v2_RS16100	COG0154	amidase activity
XCCCN05v2_RS16110	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCCCN05v2_RS16145	COG0201	protein transport
XCCCN05v2_RS16230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCCCN05v2_RS16305	COG0250	Participates in transcription elongation, termination and antitermination
XCCCN05v2_RS16340	COG0012	GTP binding
XCCCN05v2_RS16345	COG0193	aminoacyl-tRNA hydrolase activity
XCCCN05v2_RS16355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCCCN05v2_RS16395	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCCCN05v2_RS16415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN05v2_RS16445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCCCN05v2_RS16450	COG1404	Belongs to the peptidase S8 family
XCCCN05v2_RS16460	COG1404	Belongs to the peptidase S8 family
XCCCN05v2_RS16465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCCCN05v2_RS16530	COG0778	Nitroreductase
XCCCN05v2_RS16535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN05v2_RS16535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN05v2_RS16555	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN05v2_RS16565	COG3634	alkyl hydroperoxide reductase activity
XCCCN05v2_RS16570	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS16575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN05v2_RS16600	COG2197	response regulator
XCCCN05v2_RS16605	COG5002	protein histidine kinase activity
XCCCN05v2_RS16605	COG0784	Response regulator, receiver
XCCCN05v2_RS16605	COG2205	protein histidine kinase activity
XCCCN05v2_RS16635	COG0697	spore germination
XCCCN05v2_RS16665	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN05v2_RS16685	COG1024	Enoyl-CoA hydratase
XCCCN05v2_RS16695	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN05v2_RS16700	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS16705	COG3384	dioxygenase
XCCCN05v2_RS16735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN05v2_RS16740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN05v2_RS16750	COG2096	Adenosyltransferase
XCCCN05v2_RS16755	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCCCN05v2_RS16785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCCCN05v2_RS16820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCCCN05v2_RS16830	COG0642	Histidine kinase
XCCCN05v2_RS16845	COG4181	ATPase activity
XCCCN05v2_RS16855	COG2175	clavaminate synthase activity
XCCCN05v2_RS16865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCCCN05v2_RS16870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XCCCN05v2_RS16890	COG4771	TonB-dependent receptor
XCCCN05v2_RS16905	COG0667	Aldo Keto reductase
XCCCN05v2_RS16910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCCCN05v2_RS16920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN05v2_RS17015	COG0366	Alpha amylase catalytic
XCCCN05v2_RS17050	COG0604	alcohol dehydrogenase
XCCCN05v2_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS17050	COG3321	synthase
XCCCN05v2_RS17065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN05v2_RS17080	COG0494	nUDIX hydrolase
XCCCN05v2_RS17095	COG0739	heme binding
XCCCN05v2_RS17120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCCCN05v2_RS17125	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN05v2_RS17150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCCCN05v2_RS17165	COG3116	cell division
XCCCN05v2_RS17215	COG1988	membrane-bound metal-dependent
XCCCN05v2_RS17220	COG0277	FAD linked oxidase domain protein
XCCCN05v2_RS17230	COG0745	RESPONSE REGULATOR receiver
XCCCN05v2_RS17235	COG2205	protein histidine kinase activity
XCCCN05v2_RS17245	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCCCN05v2_RS17250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCCCN05v2_RS17265	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCCCN05v2_RS17295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN05v2_RS17295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN05v2_RS17320	COG0488	(ABC) transporter
XCCCN05v2_RS17325	COG0242	peptide deformylase activity
XCCCN05v2_RS17330	COG1393	Belongs to the ArsC family
XCCCN05v2_RS17350	COG0457	Tetratricopeptide repeat
XCCCN05v2_RS17400	COG2188	Transcriptional regulator
XCCCN05v2_RS17410	COG1450	Type ii and iii secretion system protein
XCCCN05v2_RS17425	COG3166	PFAM Fimbrial assembly family protein
XCCCN05v2_RS17430	COG3156	type II secretion system protein K
XCCCN05v2_RS17435	COG4795	General secretion pathway protein
XCCCN05v2_RS17440	COG2165	general secretion pathway protein
XCCCN05v2_RS17445	COG4970	Tfp pilus assembly protein FimT
XCCCN05v2_RS17450	COG2165	general secretion pathway protein
XCCCN05v2_RS17455	COG1459	type II secretion system
XCCCN05v2_RS17460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN05v2_RS17465	COG1404	Belongs to the peptidase S8 family
XCCCN05v2_RS17480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCCCN05v2_RS17480	COG0047	phosphoribosylformylglycinamidine synthase activity
XCCCN05v2_RS17485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN05v2_RS17490	COG4974	Belongs to the 'phage' integrase family
XCCCN05v2_RS17505	COG0795	lipopolysaccharide-transporting ATPase activity
XCCCN05v2_RS17565	COG1183	phosphatidylcholine synthase activity
XCCCN05v2_RS17590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN05v2_RS17595	COG1127	ABC transporter
XCCCN05v2_RS17600	COG3218	ABC-type transport auxiliary lipoprotein component
XCCCN05v2_RS17600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN05v2_RS17625	COG3754	Rhamnan synthesis protein F
XCCCN05v2_RS17630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN05v2_RS17635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN05v2_RS17640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCCCN05v2_RS17645	COG0662	Cupin 2, conserved barrel domain protein
XCCCN05v2_RS17645	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN05v2_RS17670	COG2086	electron transfer activity
XCCCN05v2_RS17685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XCCCN05v2_RS17690	COG0463	Glycosyl transferase, family 2
XCCCN05v2_RS17715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCCCN05v2_RS17730	COG0438	transferase activity, transferring glycosyl groups
XCCCN05v2_RS17755	COG0626	cystathionine gamma-synthase activity
XCCCN05v2_RS17785	COG0625	glutathione transferase activity
XCCCN05v2_RS17795	COG0513	Belongs to the DEAD box helicase family
XCCCN05v2_RS17800	COG0720	synthase
XCCCN05v2_RS17810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XCCCN05v2_RS17815	COG1956	GAF domain-containing protein
XCCCN05v2_RS17845	COG0339	signal peptide processing
XCCCN05v2_RS17850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCCCN05v2_RS17910	COG1136	(ABC) transporter
XCCCN05v2_RS17915	COG0577	efflux transmembrane transporter activity
XCCCN05v2_RS17935	COG4191	Histidine kinase
XCCCN05v2_RS18000	COG0356	it plays a direct role in the translocation of protons across the membrane
XCCCN05v2_RS18015	COG1228	amidohydrolase
XCCCN05v2_RS18020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN05v2_RS18030	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN05v2_RS18070	COG2011	ABC-type metal ion transport system permease component
XCCCN05v2_RS18080	COG0697	spore germination
XCCCN05v2_RS18115	COG1187	pseudouridine synthase activity
XCCCN05v2_RS18120	COG2813	Specifically methylates the guanine in position
XCCCN05v2_RS18140	COG5002	protein histidine kinase activity
XCCCN05v2_RS18220	COG0842	Transport permease protein
XCCCN05v2_RS18225	COG1131	(ABC) transporter
XCCCN05v2_RS18230	COG0025	NhaP-type Na H and K H
XCCCN05v2_RS18235	COG3795	YCII-related domain
XCCCN05v2_RS18240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCCCN05v2_RS18245	COG1573	uracil-dna glycosylase
XCCCN05v2_RS18255	COG3384	dioxygenase
XCCCN05v2_RS18260	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS18270	COG0667	Aldo Keto reductase
XCCCN05v2_RS18295	COG0531	amino acid
XCCCN05v2_RS18310	COG2972	Histidine kinase
XCCCN05v2_RS18335	COG1335	isochorismatase
XCCCN05v2_RS18340	COG3685	Protein conserved in bacteria
XCCCN05v2_RS18345	COG3685	Protein conserved in bacteria
XCCCN05v2_RS18350	COG3546	catalase activity
XCCCN05v2_RS18380	COG2204	response regulator
XCCCN05v2_RS18390	COG1271	oxidase subunit
XCCCN05v2_RS18395	COG1294	oxidase, subunit
XCCCN05v2_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS18415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCCCN05v2_RS18435	COG1132	(ABC) transporter
XCCCN05v2_RS18450	COG1063	alcohol dehydrogenase
XCCCN05v2_RS18490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN05v2_RS18550	COG0251	oxidation-reduction process
XCCCN05v2_RS18570	COG0667	Aldo Keto reductase
XCCCN05v2_RS18575	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS18595	COG5001	Diguanylate cyclase
XCCCN05v2_RS18595	COG4251	negative regulation of phosphorylation
XCCCN05v2_RS18595	COG2203	Gaf domain
XCCCN05v2_RS18595	COG3706	GGDEF domain
XCCCN05v2_RS18620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN05v2_RS18630	COG1560	Kdo2-lipid A biosynthetic process
XCCCN05v2_RS18640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCCCN05v2_RS18675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCCCN05v2_RS18675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCCCN05v2_RS18685	COG0242	peptide deformylase activity
XCCCN05v2_RS18690	COG1652	LysM domain
XCCCN05v2_RS18695	COG0758	DNA mediated transformation
XCCCN05v2_RS18715	COG1754	DNA topoisomerase type I activity
XCCCN05v2_RS18715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN05v2_RS18735	COG5001	Diguanylate cyclase
XCCCN05v2_RS18735	COG4251	negative regulation of phosphorylation
XCCCN05v2_RS18735	COG3706	GGDEF domain
XCCCN05v2_RS18735	COG2203	Gaf domain
XCCCN05v2_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS18750	COG0616	signal peptide processing
XCCCN05v2_RS18755	COG0534	Mate efflux family protein
XCCCN05v2_RS18770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCCCN05v2_RS18775	COG0625	glutathione transferase activity
XCCCN05v2_RS18790	COG1252	NADH dehydrogenase
XCCCN05v2_RS18795	COG2860	membrane
XCCCN05v2_RS18800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN05v2_RS18810	COG2201	protein-glutamate methylesterase activity
XCCCN05v2_RS18815	COG2177	Part of the ABC transporter FtsEX involved in
XCCCN05v2_RS18820	COG2884	Cell division ATP-binding protein ftsE
XCCCN05v2_RS18830	COG3118	belongs to the thioredoxin family
XCCCN05v2_RS18835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCCCN05v2_RS18880	COG1473	amidohydrolase
XCCCN05v2_RS18885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN05v2_RS18915	COG4941	Belongs to the sigma-70 factor family
XCCCN05v2_RS18920	COG5383	Protein conserved in bacteria
XCCCN05v2_RS18955	COG3039	Transposase
XCCCN05v2_RS18965	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCCCN05v2_RS18970	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN05v2_RS18980	COG3501	Rhs element vgr protein
XCCCN05v2_RS18980	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN05v2_RS18995	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCCCN05v2_RS19005	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN05v2_RS19015	COG0531	amino acid
XCCCN05v2_RS19030	COG4682	membrane
XCCCN05v2_RS19035	COG2133	pyrroloquinoline quinone binding
XCCCN05v2_RS19045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCCCN05v2_RS19060	COG1610	YqeY-like protein
XCCCN05v2_RS19065	COG1295	ribonuclease BN
XCCCN05v2_RS19070	COG0358	DNA primase activity
XCCCN05v2_RS19120	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCCCN05v2_RS19135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCCCN05v2_RS19180	COG0739	heme binding
XCCCN05v2_RS19200	COG0708	Exodeoxyribonuclease III
XCCCN05v2_RS19215	COG1192	Involved in chromosome partitioning
XCCCN05v2_RS19220	COG1475	DNA binding
XCCCN05v2_RS19240	COG0463	Glycosyl transferase, family 2
XCCCN05v2_RS19265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCCCN05v2_RS19290	COG4221	oxidoreductase activity
XCCCN05v2_RS19295	COG2755	lipolytic protein G-D-S-L family
XCCCN05v2_RS19295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCCCN05v2_RS19310	COG1166	arginine decarboxylase activity
XCCCN05v2_RS19335	COG2960	long-chain fatty acid transporting porin activity
XCCCN05v2_RS19340	COG0606	chelatase, subunit chli
XCCCN05v2_RS19355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCCCN05v2_RS19440	COG1090	epimerase
XCCCN05v2_RS19445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN05v2_RS19460	COG0642	Histidine kinase
XCCCN05v2_RS19480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN05v2_RS19505	COG1011	Hydrolase
XCCCN05v2_RS19510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCCCN05v2_RS19530	COG2197	response regulator
XCCCN05v2_RS19535	COG4585	Histidine kinase
XCCCN05v2_RS19550	COG1136	(ABC) transporter
XCCCN05v2_RS19575	COG0697	spore germination
XCCCN05v2_RS19615	COG0180	Tryptophanyl-tRNA synthetase
XCCCN05v2_RS19620	COG3237	CsbD-like
XCCCN05v2_RS19695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCCCN05v2_RS19695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCCCN05v2_RS19705	COG3228	Belongs to the MtfA family
XCCCN05v2_RS19735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN05v2_RS19765	COG1199	ATP-dependent helicase activity
XCCCN05v2_RS19830	COG0625	glutathione transferase activity
XCCCN05v2_RS19865	COG4555	ABC transporter
XCCCN05v2_RS19875	COG1476	TRANSCRIPTIONal
XCCCN05v2_RS19890	COG1230	cation diffusion facilitator family transporter
XCCCN05v2_RS19905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN05v2_RS19910	COG1131	(ABC) transporter
XCCCN05v2_RS19915	COG0842	Transport permease protein
XCCCN05v2_RS19925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCCCN05v2_RS19940	COG1607	acyl-coa hydrolase
XCCCN05v2_RS19955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN05v2_RS19970	COG1358	cellular component organization or biogenesis
XCCCN05v2_RS20030	COG0045	succinate-CoA ligase (ADP-forming) activity
XCCCN05v2_RS20030	COG1042	CoA-binding domain protein
XCCCN05v2_RS20030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCCCN05v2_RS20035	COG2239	Acts as a magnesium transporter
XCCCN05v2_RS20050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN05v2_RS20055	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN05v2_RS20070	COG3100	YcgL domain-containing protein
XCCCN05v2_RS20075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCCCN05v2_RS20085	COG0463	Glycosyl transferase, family 2
XCCCN05v2_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS20150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCCCN05v2_RS20220	COG0210	DNA helicase
XCCCN05v2_RS20230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS20235	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS20240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCCCN05v2_RS20250	COG2159	amidohydrolase
XCCCN05v2_RS20305	COG2091	lysine biosynthetic process via aminoadipic acid
XCCCN05v2_RS20355	COG1940	carbohydrate kinase activity
XCCCN05v2_RS20365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCCCN05v2_RS20380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCCCN05v2_RS20385	COG3162	membrane
XCCCN05v2_RS20420	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN05v2_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN05v2_RS20440	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCCCN05v2_RS20445	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN05v2_RS20450	COG3254	rhamnose metabolic process
XCCCN05v2_RS20455	COG0738	Major facilitator superfamily
XCCCN05v2_RS20460	COG1414	Transcriptional regulator
XCCCN05v2_RS20480	COG2205	protein histidine kinase activity
XCCCN05v2_RS20480	COG0784	Response regulator, receiver
XCCCN05v2_RS20485	COG3459	Glycosyltransferase 36 associated
XCCCN05v2_RS20490	COG2211	Major facilitator Superfamily
XCCCN05v2_RS20495	COG3265	gluconokinase activity
XCCCN05v2_RS20520	COG2911	Protein conserved in bacteria
XCCCN05v2_RS20525	COG0729	surface antigen
XCCCN05v2_RS20540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN05v2_RS20545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCCCN05v2_RS20545	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN05v2_RS20575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCCCN05v2_RS20610	COG3661	Belongs to the glycosyl hydrolase 67 family
XCCCN05v2_RS20620	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN05v2_RS20630	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN05v2_RS20635	COG0246	Mannitol dehydrogenase
XCCCN05v2_RS20675	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN05v2_RS20690	COG3250	beta-galactosidase activity
XCCCN05v2_RS20700	COG3693	PFAM glycoside hydrolase, family 10
XCCCN05v2_RS20715	COG2211	Major facilitator Superfamily
XCCCN05v2_RS20750	COG2937	Belongs to the GPAT DAPAT family
XCCCN05v2_RS20805	COG0210	DNA helicase
XCCCN05v2_RS20835	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCCCN05v2_RS20885	COG3135	benzoate transporter
XCCCN05v2_RS20910	COG0676	glucose-6-phosphate 1-epimerase activity
XCCCN05v2_RS20930	COG0730	response to heat
XCCCN05v2_RS20960	COG0302	gtp cyclohydrolase
XCCCN05v2_RS20975	COG1566	PFAM secretion protein HlyD family protein
XCCCN05v2_RS20985	COG1289	transmembrane transporter activity
XCCCN05v2_RS20990	COG0477	Major facilitator Superfamily
XCCCN05v2_RS21000	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS21005	COG4221	oxidoreductase activity
XCCCN05v2_RS21010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN05v2_RS21080	COG0564	pseudouridine synthase activity
XCCCN05v2_RS21130	COG1074	ATP-dependent DNA helicase activity
XCCCN05v2_RS21135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCCCN05v2_RS21170	COG1127	ABC transporter
XCCCN05v2_RS21175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN05v2_RS21180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN05v2_RS21195	COG2853	Lipoprotein
XCCCN05v2_RS21200	COG0386	Belongs to the glutathione peroxidase family
XCCCN05v2_RS21210	COG1322	Protein conserved in bacteria
XCCCN05v2_RS21220	COG0604	alcohol dehydrogenase
XCCCN05v2_RS21225	COG0583	DNA-binding transcription factor activity
XCCCN05v2_RS21240	COG0531	amino acid
XCCCN05v2_RS21250	COG4206	TonB-dependent receptor
XCCCN05v2_RS21260	COG3706	GGDEF domain
XCCCN05v2_RS21265	COG3835	regulator
XCCCN05v2_RS21270	COG1929	Belongs to the glycerate kinase type-1 family
XCCCN05v2_RS21275	COG2271	Major facilitator Superfamily
XCCCN05v2_RS21300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCCCN05v2_RS21305	COG0861	Integral membrane protein TerC family
XCCCN05v2_RS21320	COG0584	glycerophosphoryl diester phosphodiesterase
XCCCN05v2_RS21330	COG0671	phosphoesterase, PA-phosphatase related
XCCCN05v2_RS21350	COG0706	membrane insertase activity
XCCCN05v2_RS21435	COG4977	sequence-specific DNA binding
XCCCN05v2_RS21680	COG1754	DNA topoisomerase type I activity
XCCCN05v2_RS21680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN05v2_RS21760	COG3039	Transposase
XCCCN05v2_RS21810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN05v2_RS21880	COG1475	DNA binding
XCCCN05v2_RS21885	COG1192	Involved in chromosome partitioning
XCCCN05v2_RS21990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN05v2_RS21995	COG2199	diguanylate cyclase activity
XCCCN05v2_RS21995	COG2200	EAL domain
XCCCN05v2_RS21995	COG3287	FIST C domain
XCCCN05v2_RS22070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN05v2_RS22085	COG2974	May be involved in recombination
XCCCN05v2_RS22115	COG0776	regulation of translation
XCCCN05v2_RS22120	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding