locus-tag	class	description
XCCCN06v2_RS00020	COG0187	DNA topoisomerase II activity
XCCCN06v2_RS00030	COG0501	Belongs to the peptidase M48B family
XCCCN06v2_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN06v2_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN06v2_RS00105	COG0793	Belongs to the peptidase S41A family
XCCCN06v2_RS00110	COG4942	peptidase
XCCCN06v2_RS00120	COG2234	aminopeptidase activity
XCCCN06v2_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN06v2_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN06v2_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN06v2_RS00150	COG1064	alcohol dehydrogenase
XCCCN06v2_RS00160	COG0493	'glutamate synthase
XCCCN06v2_RS00165	COG0070	glutamate synthase
XCCCN06v2_RS00165	COG0067	glutamate synthase
XCCCN06v2_RS00165	COG0069	glutamate synthase activity
XCCCN06v2_RS00180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCCCN06v2_RS00190	COG1741	Belongs to the pirin family
XCCCN06v2_RS00200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCCCN06v2_RS00220	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS00280	COG1111	helicase
XCCCN06v2_RS00280	COG1205	dead DEAH box helicase
XCCCN06v2_RS00285	COG3177	Filamentation induced by cAMP protein fic
XCCCN06v2_RS00290	COG1272	protein, Hemolysin III
XCCCN06v2_RS00365	COG3237	CsbD-like
XCCCN06v2_RS00410	COG0628	permease
XCCCN06v2_RS00415	COG0657	acetylesterase activity
XCCCN06v2_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN06v2_RS00430	COG0477	Major facilitator Superfamily
XCCCN06v2_RS00470	COG0714	Associated with various cellular activities
XCCCN06v2_RS00510	COG4772	TonB-dependent receptor
XCCCN06v2_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN06v2_RS00560	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCCCN06v2_RS00565	COG4585	Histidine kinase
XCCCN06v2_RS00570	COG2197	response regulator
XCCCN06v2_RS00600	COG3710	Transcriptional regulator
XCCCN06v2_RS00620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN06v2_RS00650	COG4916	TIR domain
XCCCN06v2_RS00685	COG3039	Transposase
XCCCN06v2_RS00695	COG0366	Alpha amylase catalytic
XCCCN06v2_RS00700	COG0366	Alpha amylase catalytic
XCCCN06v2_RS00740	COG2755	lipolytic protein G-D-S-L family
XCCCN06v2_RS00750	COG2755	lipolytic protein G-D-S-L family
XCCCN06v2_RS00750	COG0657	acetylesterase activity
XCCCN06v2_RS00760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCCCN06v2_RS00775	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN06v2_RS00780	COG1609	Transcriptional regulator
XCCCN06v2_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS00800	COG2755	lipolytic protein G-D-S-L family
XCCCN06v2_RS00810	COG3186	Phenylalanine-4-hydroxylase
XCCCN06v2_RS00815	COG1522	sequence-specific DNA binding
XCCCN06v2_RS00830	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCCCN06v2_RS00840	COG1119	ATPase activity
XCCCN06v2_RS00855	COG1125	glycine betaine transport
XCCCN06v2_RS00855	COG0517	IMP dehydrogenase activity
XCCCN06v2_RS00870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN06v2_RS00875	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCCCN06v2_RS00905	COG0489	protein tyrosine kinase activity
XCCCN06v2_RS00910	COG0588	phosphoglycerate mutase activity
XCCCN06v2_RS00920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN06v2_RS00945	COG1881	PFAM PEBP family protein
XCCCN06v2_RS00960	COG0174	glutamine synthetase
XCCCN06v2_RS00965	COG0347	Belongs to the P(II) protein family
XCCCN06v2_RS00970	COG0004	ammonium transporteR
XCCCN06v2_RS00975	COG3852	Histidine kinase
XCCCN06v2_RS00980	COG2204	response regulator
XCCCN06v2_RS00990	COG2032	superoxide dismutase activity
XCCCN06v2_RS00995	COG2032	superoxide dismutase activity
XCCCN06v2_RS01000	COG0346	lactoylglutathione lyase activity
XCCCN06v2_RS01010	COG0183	Belongs to the thiolase family
XCCCN06v2_RS01050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCCCN06v2_RS01070	COG0028	Belongs to the TPP enzyme family
XCCCN06v2_RS01085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCCCN06v2_RS01100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN06v2_RS01105	COG3177	Filamentation induced by cAMP protein fic
XCCCN06v2_RS01110	COG0596	Alpha beta hydrolase
XCCCN06v2_RS01115	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCCCN06v2_RS01120	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN06v2_RS01125	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS01140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN06v2_RS01160	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN06v2_RS01175	COG0564	pseudouridine synthase activity
XCCCN06v2_RS01195	COG1446	asparaginase
XCCCN06v2_RS01200	COG0339	signal peptide processing
XCCCN06v2_RS01230	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS01235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCCCN06v2_RS01240	COG2224	Isocitrate lyase
XCCCN06v2_RS01245	COG3039	Transposase
XCCCN06v2_RS01275	COG4770	biotin carboxylase activity
XCCCN06v2_RS01280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCCCN06v2_RS01285	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS01340	COG0523	cobalamin synthesis protein
XCCCN06v2_RS01350	COG0697	spore germination
XCCCN06v2_RS01360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCCCN06v2_RS01370	COG1846	Transcriptional regulator
XCCCN06v2_RS01375	COG1764	response to oxidative stress
XCCCN06v2_RS01405	COG0656	L-ascorbic acid biosynthetic process
XCCCN06v2_RS01410	COG2130	NADP-dependent
XCCCN06v2_RS01425	COG1187	pseudouridine synthase activity
XCCCN06v2_RS01435	COG1643	Atp-dependent helicase
XCCCN06v2_RS01440	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS01445	COG4807	Protein conserved in bacteria
XCCCN06v2_RS01450	COG2351	hydroxyisourate hydrolase activity
XCCCN06v2_RS01455	COG2072	flavoprotein involved in K transport
XCCCN06v2_RS01475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCCCN06v2_RS01500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN06v2_RS01515	COG1957	nucleoside hydrolase
XCCCN06v2_RS01525	COG2252	PERMEase
XCCCN06v2_RS01545	COG0084	hydrolase, TatD family'
XCCCN06v2_RS01555	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS01560	COG2814	Major facilitator Superfamily
XCCCN06v2_RS01585	COG1902	pentaerythritol trinitrate reductase activity
XCCCN06v2_RS01610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN06v2_RS01615	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS01645	COG3321	synthase
XCCCN06v2_RS01645	COG0604	alcohol dehydrogenase
XCCCN06v2_RS01655	COG0702	epimerase
XCCCN06v2_RS01660	COG1733	regulation of RNA biosynthetic process
XCCCN06v2_RS01670	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS01760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCCCN06v2_RS01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCCCN06v2_RS01845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN06v2_RS01850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN06v2_RS01860	COG3485	protocatechuate 3,4-dioxygenase
XCCCN06v2_RS01865	COG3485	protocatechuate 3,4-dioxygenase
XCCCN06v2_RS01870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XCCCN06v2_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN06v2_RS01880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCCCN06v2_RS01890	COG1414	Transcriptional regulator
XCCCN06v2_RS01900	COG0657	acetylesterase activity
XCCCN06v2_RS01920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCCCN06v2_RS01970	COG1040	competence protein
XCCCN06v2_RS01985	COG0582	viral genome integration into host DNA
XCCCN06v2_RS01995	COG4774	siderophore transport
XCCCN06v2_RS02000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN06v2_RS02020	COG4206	TonB-dependent receptor
XCCCN06v2_RS02040	COG1511	domain protein
XCCCN06v2_RS02040	COG3264	Mechanosensitive ion channel
XCCCN06v2_RS02055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCCCN06v2_RS02060	COG2354	Protein conserved in bacteria
XCCCN06v2_RS02065	COG1649	PFAM Uncharacterised BCR, COG1649
XCCCN06v2_RS02075	COG0297	glycogen (starch) synthase activity
XCCCN06v2_RS02085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCCCN06v2_RS02110	COG0702	epimerase
XCCCN06v2_RS02155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN06v2_RS02160	COG2085	NADP oxidoreductase coenzyme F420-dependent
XCCCN06v2_RS02175	COG0513	Belongs to the DEAD box helicase family
XCCCN06v2_RS02185	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN06v2_RS02200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCCCN06v2_RS02215	COG3104	oligopeptide transport
XCCCN06v2_RS02235	COG2852	Protein conserved in bacteria
XCCCN06v2_RS02260	COG1320	monovalent cation:proton antiporter activity
XCCCN06v2_RS02265	COG2212	antiporter activity
XCCCN06v2_RS02275	COG0651	ATP synthesis coupled electron transport
XCCCN06v2_RS02280	COG1006	Multisubunit Na H antiporter MnhC subunit
XCCCN06v2_RS02285	COG2111	Na H antiporter
XCCCN06v2_RS02285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCCCN06v2_RS02365	COG0436	Aminotransferase
XCCCN06v2_RS02380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCCCN06v2_RS02485	COG2816	NAD+ diphosphatase activity
XCCCN06v2_RS02490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN06v2_RS02520	COG2814	Major facilitator Superfamily
XCCCN06v2_RS02530	COG1289	transmembrane transporter activity
XCCCN06v2_RS02535	COG0151	Belongs to the GarS family
XCCCN06v2_RS02550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN06v2_RS02555	COG2267	carboxylic ester hydrolase activity
XCCCN06v2_RS02560	COG0671	phosphoesterase, PA-phosphatase related
XCCCN06v2_RS02560	COG2453	phosphatase
XCCCN06v2_RS02585	COG4589	Belongs to the CDS family
XCCCN06v2_RS02600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCCCN06v2_RS02640	COG0439	Biotin carboxylase
XCCCN06v2_RS02650	COG0511	ligase activity, forming carbon-carbon bonds
XCCCN06v2_RS02665	COG1324	tolerance protein
XCCCN06v2_RS02670	COG2356	endonuclease I
XCCCN06v2_RS02685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCCCN06v2_RS02695	COG1196	nuclear chromosome segregation
XCCCN06v2_RS02725	COG3550	peptidyl-serine autophosphorylation
XCCCN06v2_RS02735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCCCN06v2_RS02760	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN06v2_RS02775	COG3712	iron ion homeostasis
XCCCN06v2_RS02815	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN06v2_RS02840	COG2353	YceI-like domain
XCCCN06v2_RS02990	COG1595	DNA-templated transcription, initiation
XCCCN06v2_RS03005	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN06v2_RS03005	COG1506	peptidase
XCCCN06v2_RS03010	COG0367	asparagine synthase
XCCCN06v2_RS03060	COG0435	Glutathione S-transferase
XCCCN06v2_RS03120	COG2409	Drug exporters of the RND superfamily
XCCCN06v2_RS03130	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN06v2_RS03130	COG1506	peptidase
XCCCN06v2_RS03145	COG1959	2 iron, 2 sulfur cluster binding
XCCCN06v2_RS03180	COG0697	spore germination
XCCCN06v2_RS03195	COG4305	rare lipoprotein A
XCCCN06v2_RS03200	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN06v2_RS03210	COG1113	amino acid transport
XCCCN06v2_RS03275	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN06v2_RS03275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN06v2_RS03280	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN06v2_RS03285	COG3706	GGDEF domain
XCCCN06v2_RS03300	COG3273	potassium ion transport
XCCCN06v2_RS03300	COG0471	metal ion transport
XCCCN06v2_RS03315	COG3275	phosphorelay sensor kinase activity
XCCCN06v2_RS03355	COG1505	serine-type exopeptidase activity
XCCCN06v2_RS03370	COG0436	Aminotransferase
XCCCN06v2_RS03380	COG2832	Protein of unknown function (DUF454)
XCCCN06v2_RS03440	COG2226	methyltransferase
XCCCN06v2_RS03445	COG3300	MHYT domain
XCCCN06v2_RS03445	COG5001	Diguanylate cyclase
XCCCN06v2_RS03450	COG0308	aminopeptidase N
XCCCN06v2_RS03485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCCCN06v2_RS03495	COG3284	Transcriptional regulator
XCCCN06v2_RS03500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN06v2_RS03505	COG1077	Cell shape determining protein MreB Mrl
XCCCN06v2_RS03515	COG1792	Involved in formation and maintenance of cell shape
XCCCN06v2_RS03530	COG0772	Belongs to the SEDS family
XCCCN06v2_RS03570	COG2951	lytic endotransglycosylase activity
XCCCN06v2_RS03575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCCCN06v2_RS03580	COG1686	Belongs to the peptidase S11 family
XCCCN06v2_RS03625	COG1051	belongs to the nudix hydrolase family
XCCCN06v2_RS03625	COG1056	cytidyltransferase-related domain
XCCCN06v2_RS03660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCCCN06v2_RS03665	COG0673	inositol 2-dehydrogenase activity
XCCCN06v2_RS03670	COG2823	Periplasmic or secreted lipoprotein
XCCCN06v2_RS03675	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS03680	COG0784	Response regulator, receiver
XCCCN06v2_RS03685	COG4191	Histidine kinase
XCCCN06v2_RS03690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCCCN06v2_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS03740	COG1459	type II secretion system
XCCCN06v2_RS03755	COG2165	general secretion pathway protein
XCCCN06v2_RS03760	COG4795	General secretion pathway protein
XCCCN06v2_RS03785	COG2188	Transcriptional regulator
XCCCN06v2_RS03795	COG1609	Transcriptional regulator
XCCCN06v2_RS03800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN06v2_RS03805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCCCN06v2_RS03845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCCCN06v2_RS03855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN06v2_RS03880	COG2205	protein histidine kinase activity
XCCCN06v2_RS03900	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS03920	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCCCN06v2_RS03930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN06v2_RS03940	COG0697	spore germination
XCCCN06v2_RS03950	COG1307	EDD domain protein, DegV family
XCCCN06v2_RS03990	COG1228	amidohydrolase
XCCCN06v2_RS04010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN06v2_RS04030	COG0436	Aminotransferase
XCCCN06v2_RS04085	COG1162	GTPase activity
XCCCN06v2_RS04110	COG2211	Major facilitator Superfamily
XCCCN06v2_RS04115	COG1609	Transcriptional regulator
XCCCN06v2_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS04125	COG2851	Citrate transporter
XCCCN06v2_RS04140	COG0642	Histidine kinase
XCCCN06v2_RS04150	COG2197	response regulator
XCCCN06v2_RS04160	COG4191	Histidine kinase
XCCCN06v2_RS04200	COG1560	Kdo2-lipid A biosynthetic process
XCCCN06v2_RS04205	COG1519	Transferase
XCCCN06v2_RS04210	COG1538	Outer membrane efflux protein
XCCCN06v2_RS04215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCCCN06v2_RS04225	COG3300	MHYT domain
XCCCN06v2_RS04225	COG5001	Diguanylate cyclase
XCCCN06v2_RS04235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCCCN06v2_RS04245	COG2226	methyltransferase
XCCCN06v2_RS04280	COG0405	Gamma-glutamyltransferase
XCCCN06v2_RS04285	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS04290	COG1506	peptidase
XCCCN06v2_RS04290	COG4946	Tricorn protease homolog
XCCCN06v2_RS04290	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN06v2_RS04325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCCCN06v2_RS04340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCCCN06v2_RS04355	COG3039	Transposase
XCCCN06v2_RS04370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCCCN06v2_RS04380	COG3781	membrane
XCCCN06v2_RS04385	COG0671	phosphoesterase, PA-phosphatase related
XCCCN06v2_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS04405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN06v2_RS04410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCCCN06v2_RS04440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN06v2_RS04470	COG1773	rubredoxin
XCCCN06v2_RS04475	COG2912	Transglutaminase-like superfamily
XCCCN06v2_RS04495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCCCN06v2_RS04520	COG0006	proline dipeptidase activity
XCCCN06v2_RS04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCCCN06v2_RS04555	COG0346	lactoylglutathione lyase activity
XCCCN06v2_RS04565	COG1561	YicC-like family, N-terminal region
XCCCN06v2_RS04580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN06v2_RS04590	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS04605	COG2271	Major facilitator Superfamily
XCCCN06v2_RS04620	COG2721	sulfolactate sulfo-lyase activity
XCCCN06v2_RS04630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCCCN06v2_RS04655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCCCN06v2_RS04685	COG0714	Associated with various cellular activities
XCCCN06v2_RS04705	COG2304	oxidoreductase activity
XCCCN06v2_RS04715	COG1301	dicarboxylic acid transport
XCCCN06v2_RS04720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCCCN06v2_RS04725	COG0596	Alpha beta hydrolase
XCCCN06v2_RS04730	COG4773	Receptor
XCCCN06v2_RS04735	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS04745	COG0739	heme binding
XCCCN06v2_RS04750	COG1376	ErfK ybiS ycfS ynhG family protein
XCCCN06v2_RS04780	COG4149	molybdate abc transporter
XCCCN06v2_RS04785	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCCCN06v2_RS04790	COG3453	Protein conserved in bacteria
XCCCN06v2_RS04790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN06v2_RS04805	COG3047	cAMP biosynthetic process
XCCCN06v2_RS04820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCCCN06v2_RS04850	COG0469	pyruvate kinase activity
XCCCN06v2_RS04855	COG3588	fructose-bisphosphate aldolase
XCCCN06v2_RS04860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCCCN06v2_RS04890	COG2205	protein histidine kinase activity
XCCCN06v2_RS04890	COG2198	Histidine kinase
XCCCN06v2_RS04890	COG0784	Response regulator, receiver
XCCCN06v2_RS04920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN06v2_RS04930	COG2895	sulfate adenylyltransferase (ATP) activity
XCCCN06v2_RS04930	COG0529	Catalyzes the synthesis of activated sulfate
XCCCN06v2_RS04935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN06v2_RS04940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN06v2_RS04945	COG0308	aminopeptidase N
XCCCN06v2_RS04955	COG1115	amino acid carrier protein
XCCCN06v2_RS04960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN06v2_RS04965	COG2272	Belongs to the type-B carboxylesterase lipase family
XCCCN06v2_RS04970	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN06v2_RS04975	COG3250	beta-galactosidase activity
XCCCN06v2_RS04990	COG1609	Transcriptional regulator
XCCCN06v2_RS05020	COG0471	metal ion transport
XCCCN06v2_RS05020	COG3273	potassium ion transport
XCCCN06v2_RS05050	COG0582	viral genome integration into host DNA
XCCCN06v2_RS05080	COG4195	phage-related replication protein
XCCCN06v2_RS05100	COG0084	hydrolase, TatD family'
XCCCN06v2_RS05135	COG2003	Belongs to the UPF0758 family
XCCCN06v2_RS05225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XCCCN06v2_RS05380	COG1192	Involved in chromosome partitioning
XCCCN06v2_RS05395	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS05400	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS05440	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS05475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCCCN06v2_RS05480	COG1459	type II secretion system
XCCCN06v2_RS05530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN06v2_RS05530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCCCN06v2_RS05540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN06v2_RS05545	COG0564	pseudouridine synthase activity
XCCCN06v2_RS05565	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS05580	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN06v2_RS05585	COG1877	trehalose-phosphatase activity
XCCCN06v2_RS05630	COG1116	anion transmembrane transporter activity
XCCCN06v2_RS05635	COG0542	response to heat
XCCCN06v2_RS05650	COG4206	TonB-dependent receptor
XCCCN06v2_RS05670	COG1797	cobyrinic acid a,c-diamide synthase activity
XCCCN06v2_RS05675	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN06v2_RS05705	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCCCN06v2_RS05720	COG0019	diaminopimelate decarboxylase activity
XCCCN06v2_RS05725	COG4264	IucA IucC family
XCCCN06v2_RS05730	COG2814	Major facilitator Superfamily
XCCCN06v2_RS05735	COG4264	IucA IucC family
XCCCN06v2_RS05745	COG4772	TonB-dependent receptor
XCCCN06v2_RS05755	COG4651	solute:proton antiporter activity
XCCCN06v2_RS05755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN06v2_RS05795	COG0488	(ABC) transporter
XCCCN06v2_RS05815	COG2755	lipolytic protein G-D-S-L family
XCCCN06v2_RS05815	COG0657	acetylesterase activity
XCCCN06v2_RS05835	COG0477	Major facilitator Superfamily
XCCCN06v2_RS05905	COG0824	Thioesterase
XCCCN06v2_RS05915	COG0848	biopolymer transport protein
XCCCN06v2_RS05930	COG2885	chlorophyll binding
XCCCN06v2_RS05940	COG0602	queuosine metabolic process
XCCCN06v2_RS05985	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS06010	COG1187	pseudouridine synthase activity
XCCCN06v2_RS06025	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN06v2_RS06030	COG0783	Belongs to the Dps family
XCCCN06v2_RS06035	COG1643	Atp-dependent helicase
XCCCN06v2_RS06085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN06v2_RS06095	COG1215	transferase activity, transferring glycosyl groups
XCCCN06v2_RS06100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCCCN06v2_RS06110	COG1199	ATP-dependent helicase activity
XCCCN06v2_RS06135	COG0189	ligase activity
XCCCN06v2_RS06150	COG0835	chemotaxis
XCCCN06v2_RS06155	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS06160	COG0643	Histidine kinase
XCCCN06v2_RS06160	COG2198	Histidine kinase
XCCCN06v2_RS06160	COG0784	Response regulator, receiver
XCCCN06v2_RS06190	COG1595	DNA-templated transcription, initiation
XCCCN06v2_RS06195	COG2304	oxidoreductase activity
XCCCN06v2_RS06200	COG1446	asparaginase
XCCCN06v2_RS06215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XCCCN06v2_RS06260	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN06v2_RS06275	COG3645	SOS response
XCCCN06v2_RS06320	COG3537	Alpha-1,2-mannosidase
XCCCN06v2_RS06330	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN06v2_RS06340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCCCN06v2_RS06345	COG1388	LysM domain
XCCCN06v2_RS06345	COG3858	chitin binding
XCCCN06v2_RS06370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCCCN06v2_RS06380	COG0494	nUDIX hydrolase
XCCCN06v2_RS06385	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCCCN06v2_RS06390	COG3956	TIGRFAM MazG family protein
XCCCN06v2_RS06405	COG0330	HflC and HflK could
XCCCN06v2_RS06455	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS06460	COG2267	carboxylic ester hydrolase activity
XCCCN06v2_RS06465	COG1309	transcriptional regulator
XCCCN06v2_RS06480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCCCN06v2_RS06490	COG0463	Glycosyl transferase, family 2
XCCCN06v2_RS06495	COG0517	IMP dehydrogenase activity
XCCCN06v2_RS06495	COG0516	GMP reductase activity
XCCCN06v2_RS06500	COG2982	Protein involved in outer membrane biogenesis
XCCCN06v2_RS06505	COG1272	protein, Hemolysin III
XCCCN06v2_RS06520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN06v2_RS06525	COG0626	cystathionine gamma-synthase activity
XCCCN06v2_RS06530	COG0460	homoserine dehydrogenase
XCCCN06v2_RS06530	COG0527	aspartate kinase activity
XCCCN06v2_RS06545	COG1760	l-serine dehydratase
XCCCN06v2_RS06565	COG2353	YceI-like domain
XCCCN06v2_RS06585	COG0477	Major facilitator Superfamily
XCCCN06v2_RS06625	COG1842	Phage shock protein A
XCCCN06v2_RS06650	COG0754	glutathionylspermidine amidase activity
XCCCN06v2_RS06660	COG2814	Major facilitator Superfamily
XCCCN06v2_RS06730	COG0531	amino acid
XCCCN06v2_RS06735	COG2197	response regulator
XCCCN06v2_RS06755	COG1113	amino acid transport
XCCCN06v2_RS06760	COG1271	oxidase subunit
XCCCN06v2_RS06765	COG1294	oxidase, subunit
XCCCN06v2_RS06775	COG2239	Acts as a magnesium transporter
XCCCN06v2_RS06780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN06v2_RS06785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN06v2_RS06805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN06v2_RS06820	COG1137	ATPase activity
XCCCN06v2_RS06835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCCCN06v2_RS06845	COG0271	Belongs to the BolA IbaG family
XCCCN06v2_RS06870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCCCN06v2_RS06890	COG0628	permease
XCCCN06v2_RS06900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN06v2_RS06915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN06v2_RS06920	COG1555	photosystem II stabilization
XCCCN06v2_RS06965	COG4774	siderophore transport
XCCCN06v2_RS06970	COG2146	nitrite reductase [NAD(P)H] activity
XCCCN06v2_RS06980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN06v2_RS06985	COG0719	Fe-S assembly protein
XCCCN06v2_RS06990	COG0396	ATPase activity
XCCCN06v2_RS06995	COG0719	Fe-S assembly protein
XCCCN06v2_RS07010	COG0693	protein deglycase activity
XCCCN06v2_RS07050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCCCN06v2_RS07080	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN06v2_RS07085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCCCN06v2_RS07105	COG1764	response to oxidative stress
XCCCN06v2_RS07115	COG0384	phenazine biosynthesis protein PhzF
XCCCN06v2_RS07120	COG0384	phenazine biosynthesis protein PhzF
XCCCN06v2_RS07125	COG0527	aspartate kinase activity
XCCCN06v2_RS07150	COG0142	geranyltranstransferase activity
XCCCN06v2_RS07155	COG0629	single-stranded DNA binding
XCCCN06v2_RS07165	COG3713	MltA-interacting MipA family protein
XCCCN06v2_RS07175	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS07180	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS07185	COG2203	Gaf domain
XCCCN06v2_RS07185	COG3706	GGDEF domain
XCCCN06v2_RS07185	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS07185	COG5001	Diguanylate cyclase
XCCCN06v2_RS07190	COG0604	alcohol dehydrogenase
XCCCN06v2_RS07195	COG2080	2 iron, 2 sulfur cluster binding
XCCCN06v2_RS07200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN06v2_RS07205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN06v2_RS07210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCCCN06v2_RS07245	COG2879	small protein
XCCCN06v2_RS07250	COG1966	Carbon starvation protein
XCCCN06v2_RS07255	COG1741	Belongs to the pirin family
XCCCN06v2_RS07275	COG1741	Belongs to the pirin family
XCCCN06v2_RS07295	COG3590	peptidase
XCCCN06v2_RS07310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN06v2_RS07320	COG0835	chemotaxis
XCCCN06v2_RS07325	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS07330	COG2198	Histidine kinase
XCCCN06v2_RS07330	COG0643	Histidine kinase
XCCCN06v2_RS07340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCCCN06v2_RS07355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCCCN06v2_RS07360	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS07365	COG2205	protein histidine kinase activity
XCCCN06v2_RS07370	COG4452	Inner membrane protein CreD
XCCCN06v2_RS07405	COG0735	belongs to the Fur family
XCCCN06v2_RS07420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN06v2_RS07430	COG1309	transcriptional regulator
XCCCN06v2_RS07435	COG0667	Aldo Keto reductase
XCCCN06v2_RS07450	COG2207	Transcriptional regulator
XCCCN06v2_RS07470	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS07475	COG2814	Major facilitator Superfamily
XCCCN06v2_RS07505	COG3383	formate dehydrogenase (NAD+) activity
XCCCN06v2_RS07520	COG1294	oxidase, subunit
XCCCN06v2_RS07615	COG5001	Diguanylate cyclase
XCCCN06v2_RS07615	COG5002	protein histidine kinase activity
XCCCN06v2_RS07620	COG1187	pseudouridine synthase activity
XCCCN06v2_RS07645	COG0475	glutathione-regulated potassium exporter activity
XCCCN06v2_RS07650	COG1132	(ABC) transporter
XCCCN06v2_RS07705	COG2155	Conserved Protein
XCCCN06v2_RS07715	COG3118	belongs to the thioredoxin family
XCCCN06v2_RS07740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCCCN06v2_RS07770	COG2968	Membrane
XCCCN06v2_RS07785	COG3164	Protein of unknown function
XCCCN06v2_RS07795	COG0312	modulator of DNA gyrase
XCCCN06v2_RS07805	COG0312	modulator of DNA gyrase
XCCCN06v2_RS07825	COG0142	geranyltranstransferase activity
XCCCN06v2_RS07845	COG1301	dicarboxylic acid transport
XCCCN06v2_RS07850	COG4106	trans-aconitate 2-methyltransferase activity
XCCCN06v2_RS07865	COG4191	Histidine kinase
XCCCN06v2_RS07895	COG0791	NLP P60 protein
XCCCN06v2_RS07900	COG0791	NLP P60 protein
XCCCN06v2_RS07905	COG1047	Peptidyl-prolyl cis-trans
XCCCN06v2_RS07910	COG2311	Membrane
XCCCN06v2_RS07915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN06v2_RS07920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN06v2_RS07940	COG3590	peptidase
XCCCN06v2_RS07945	COG3590	peptidase
XCCCN06v2_RS07965	COG0489	protein tyrosine kinase activity
XCCCN06v2_RS07970	COG0717	Belongs to the dCTP deaminase family
XCCCN06v2_RS08015	COG0494	nUDIX hydrolase
XCCCN06v2_RS08030	COG0433	COG0433 Predicted ATPase
XCCCN06v2_RS08055	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN06v2_RS08070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCCCN06v2_RS08075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCCCN06v2_RS08160	COG0300	oxidoreductase activity
XCCCN06v2_RS08180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCCCN06v2_RS08200	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCCCN06v2_RS08205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCCCN06v2_RS08225	COG0839	Belongs to the complex I subunit 6 family
XCCCN06v2_RS08245	COG1007	ATP synthesis coupled electron transport
XCCCN06v2_RS08260	COG0195	Participates in both transcription termination and antitermination
XCCCN06v2_RS08320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN06v2_RS08330	COG2095	MarC family integral membrane protein
XCCCN06v2_RS08340	COG1611	Belongs to the LOG family
XCCCN06v2_RS08345	COG3275	phosphorelay sensor kinase activity
XCCCN06v2_RS08390	COG4969	Belongs to the N-Me-Phe pilin family
XCCCN06v2_RS08410	COG3505	Type IV secretory pathway VirD4
XCCCN06v2_RS08430	COG2948	multi-organism process
XCCCN06v2_RS08450	COG3702	type iv secretory pathway
XCCCN06v2_RS08480	COG3501	Rhs element vgr protein
XCCCN06v2_RS08480	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN06v2_RS08510	COG0366	Alpha amylase catalytic
XCCCN06v2_RS08525	COG1082	Xylose isomerase domain protein TIM barrel
XCCCN06v2_RS08555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCCCN06v2_RS08625	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS08630	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS08635	COG2244	polysaccharide biosynthetic process
XCCCN06v2_RS08640	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS08665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN06v2_RS08670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN06v2_RS08675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN06v2_RS08705	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN06v2_RS08760	COG0784	Response regulator, receiver
XCCCN06v2_RS08760	COG4191	Histidine kinase
XCCCN06v2_RS08780	COG0552	protein localization to endoplasmic reticulum
XCCCN06v2_RS08790	COG3938	Belongs to the proline racemase family
XCCCN06v2_RS08810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN06v2_RS08820	COG0006	proline dipeptidase activity
XCCCN06v2_RS08845	COG0531	amino acid
XCCCN06v2_RS08925	COG0326	Molecular chaperone. Has ATPase activity
XCCCN06v2_RS08930	COG0742	ribosomal rna small subunit methyltransferase
XCCCN06v2_RS08950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCCCN06v2_RS08955	COG0405	Gamma-glutamyltransferase
XCCCN06v2_RS08960	COG3291	Pkd domain containing protein
XCCCN06v2_RS08990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCCCN06v2_RS09010	COG1862	Preprotein translocase
XCCCN06v2_RS09020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCCCN06v2_RS09035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN06v2_RS09035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN06v2_RS09040	COG1105	Belongs to the carbohydrate kinase PfkB family
XCCCN06v2_RS09045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN06v2_RS09045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN06v2_RS09050	COG1609	Transcriptional regulator
XCCCN06v2_RS09055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN06v2_RS09060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN06v2_RS09070	COG2902	Dehydrogenase
XCCCN06v2_RS09075	COG1609	Transcriptional regulator
XCCCN06v2_RS09075	COG2207	Transcriptional regulator
XCCCN06v2_RS09080	COG1335	isochorismatase
XCCCN06v2_RS09085	COG0477	Major facilitator Superfamily
XCCCN06v2_RS09095	COG2205	protein histidine kinase activity
XCCCN06v2_RS09095	COG5002	protein histidine kinase activity
XCCCN06v2_RS09095	COG0784	Response regulator, receiver
XCCCN06v2_RS09100	COG2733	membrane
XCCCN06v2_RS09110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCCCN06v2_RS09115	COG2223	nitrite transmembrane transporter activity
XCCCN06v2_RS09125	COG0243	molybdopterin cofactor binding
XCCCN06v2_RS09135	COG0477	Major facilitator Superfamily
XCCCN06v2_RS09140	COG2703	oxygen carrier activity
XCCCN06v2_RS09150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN06v2_RS09155	COG0174	glutamine synthetase
XCCCN06v2_RS09160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCCCN06v2_RS09195	COG3842	ATPase activity
XCCCN06v2_RS09205	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCCCN06v2_RS09210	COG1177	transmembrane transport
XCCCN06v2_RS09220	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN06v2_RS09235	COG4535	Mg2 and Co2 transporter CorC
XCCCN06v2_RS09255	COG1702	phosphate starvation-inducible protein PhoH
XCCCN06v2_RS09275	COG0741	lytic transglycosylase activity
XCCCN06v2_RS09280	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN06v2_RS09285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCCCN06v2_RS09290	COG2857	Cytochrome c1
XCCCN06v2_RS09295	COG0625	glutathione transferase activity
XCCCN06v2_RS09300	COG2969	positive regulation of protein catabolic process
XCCCN06v2_RS09315	COG1201	RNA secondary structure unwinding
XCCCN06v2_RS09325	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS09330	COG0835	chemotaxis
XCCCN06v2_RS09375	COG0582	viral genome integration into host DNA
XCCCN06v2_RS09405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN06v2_RS09420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCCCN06v2_RS09425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCCCN06v2_RS09425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN06v2_RS09435	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN06v2_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS09475	COG3300	MHYT domain
XCCCN06v2_RS09475	COG5001	Diguanylate cyclase
XCCCN06v2_RS09480	COG2081	HI0933 family
XCCCN06v2_RS09485	COG4681	YaeQ
XCCCN06v2_RS09520	COG0513	Belongs to the DEAD box helicase family
XCCCN06v2_RS09525	COG0488	(ABC) transporter
XCCCN06v2_RS09540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN06v2_RS09545	COG0483	inositol monophosphate 1-phosphatase activity
XCCCN06v2_RS09560	COG3300	MHYT domain
XCCCN06v2_RS09560	COG5001	Diguanylate cyclase
XCCCN06v2_RS09565	COG1509	lysine 2,3-aminomutase activity
XCCCN06v2_RS09580	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN06v2_RS09630	COG4302	ethanolamine ammonia-lyase activity
XCCCN06v2_RS09650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCCCN06v2_RS09675	COG2166	iron-sulfur cluster assembly
XCCCN06v2_RS09690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCCCN06v2_RS09700	COG0137	argininosuccinate synthase activity
XCCCN06v2_RS09705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN06v2_RS09710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCCCN06v2_RS09740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XCCCN06v2_RS09775	COG1294	oxidase, subunit
XCCCN06v2_RS09785	COG4988	ABC transporter
XCCCN06v2_RS09790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCCCN06v2_RS09855	COG0436	Aminotransferase
XCCCN06v2_RS09880	COG1187	pseudouridine synthase activity
XCCCN06v2_RS09885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCCCN06v2_RS09890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCCCN06v2_RS09895	COG2350	Protein conserved in bacteria
XCCCN06v2_RS09930	COG0395	ABC-type sugar transport system, permease component
XCCCN06v2_RS09955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN06v2_RS09960	COG2957	Belongs to the agmatine deiminase family
XCCCN06v2_RS09980	COG0539	negative regulation of cytoplasmic translation
XCCCN06v2_RS09995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCCCN06v2_RS10010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCCCN06v2_RS10015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN06v2_RS10015	COG0475	glutathione-regulated potassium exporter activity
XCCCN06v2_RS10040	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN06v2_RS10065	COG2197	response regulator
XCCCN06v2_RS10080	COG1335	isochorismatase
XCCCN06v2_RS10095	COG2814	Major facilitator Superfamily
XCCCN06v2_RS10110	COG1914	H( )-stimulated, divalent metal cation uptake system
XCCCN06v2_RS10130	COG0668	transmembrane transport
XCCCN06v2_RS10160	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS10165	COG1183	phosphatidylcholine synthase activity
XCCCN06v2_RS10175	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCCCN06v2_RS10190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN06v2_RS10190	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN06v2_RS10205	COG5001	Diguanylate cyclase
XCCCN06v2_RS10270	COG0800	Aldolase
XCCCN06v2_RS10275	COG0129	dihydroxy-acid dehydratase activity
XCCCN06v2_RS10280	COG0363	glucosamine-6-phosphate deaminase activity
XCCCN06v2_RS10290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN06v2_RS10300	COG0354	folic acid binding
XCCCN06v2_RS10315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCCCN06v2_RS10330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCCCN06v2_RS10345	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCCCN06v2_RS10365	COG0811	peptide transport
XCCCN06v2_RS10390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCCCN06v2_RS10405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN06v2_RS10435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCCCN06v2_RS10470	COG1530	ribonuclease E activity
XCCCN06v2_RS10480	COG0428	transporter
XCCCN06v2_RS10515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN06v2_RS10745	COG3279	Response regulator of the LytR AlgR family
XCCCN06v2_RS10760	COG0784	Response regulator, receiver
XCCCN06v2_RS10760	COG4191	Histidine kinase
XCCCN06v2_RS10765	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS10800	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS10810	COG1238	metal cluster binding
XCCCN06v2_RS10840	COG1733	regulation of RNA biosynthetic process
XCCCN06v2_RS10855	COG1999	signal sequence binding
XCCCN06v2_RS10870	COG3590	peptidase
XCCCN06v2_RS10940	COG5001	Diguanylate cyclase
XCCCN06v2_RS10950	COG2201	protein-glutamate methylesterase activity
XCCCN06v2_RS10955	COG3685	Protein conserved in bacteria
XCCCN06v2_RS11010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN06v2_RS11035	COG0579	oxidoreductase
XCCCN06v2_RS11045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN06v2_RS11055	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCCCN06v2_RS11075	COG0243	molybdopterin cofactor binding
XCCCN06v2_RS11085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCCCN06v2_RS11090	COG2223	nitrite transmembrane transporter activity
XCCCN06v2_RS11095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCCCN06v2_RS11105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCCCN06v2_RS11105	COG1648	precorrin-2 dehydrogenase activity
XCCCN06v2_RS11115	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN06v2_RS11120	COG0303	'Molybdopterin
XCCCN06v2_RS11130	COG0708	Exodeoxyribonuclease III
XCCCN06v2_RS11155	COG2124	cytochrome p450
XCCCN06v2_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS11175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCCCN06v2_RS11190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN06v2_RS11225	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCCCN06v2_RS11230	COG0183	Belongs to the thiolase family
XCCCN06v2_RS11235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCCCN06v2_RS11240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCCCN06v2_RS11260	COG1674	ftsk spoiiie
XCCCN06v2_RS11265	COG0492	ferredoxin-NADP+ reductase activity
XCCCN06v2_RS11285	COG0542	response to heat
XCCCN06v2_RS11305	COG2915	High frequency lysogenization protein hflD homolog
XCCCN06v2_RS11340	COG4191	Histidine kinase
XCCCN06v2_RS11360	COG0784	Response regulator, receiver
XCCCN06v2_RS11360	COG0835	chemotaxis
XCCCN06v2_RS11370	COG1558	bacterial-type flagellum-dependent cell motility
XCCCN06v2_RS11375	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCCCN06v2_RS11385	COG4787	bacterial-type flagellum-dependent cell motility
XCCCN06v2_RS11405	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCCCN06v2_RS11405	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCCCN06v2_RS11415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN06v2_RS11420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN06v2_RS11425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCCCN06v2_RS11455	COG2201	protein-glutamate methylesterase activity
XCCCN06v2_RS11475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN06v2_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS11520	COG1677	Flagellar hook-basal body complex protein FliE
XCCCN06v2_RS11585	COG1987	bacterial-type flagellum assembly
XCCCN06v2_RS11590	COG1684	flagellar biosynthetic protein fliR
XCCCN06v2_RS11645	COG0643	Histidine kinase
XCCCN06v2_RS11645	COG0784	Response regulator, receiver
XCCCN06v2_RS11645	COG2198	Histidine kinase
XCCCN06v2_RS11755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCCCN06v2_RS11760	COG1360	Flagellar Motor Protein
XCCCN06v2_RS11765	COG1192	Involved in chromosome partitioning
XCCCN06v2_RS11770	COG0835	chemotaxis
XCCCN06v2_RS11780	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS11790	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11800	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11805	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11810	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11815	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11820	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11825	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11835	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11845	COG0835	chemotaxis
XCCCN06v2_RS11855	COG0840	transmembrane signaling receptor activity
XCCCN06v2_RS11885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN06v2_RS11915	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN06v2_RS11920	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS11925	COG0784	Response regulator, receiver
XCCCN06v2_RS11925	COG2198	Histidine kinase
XCCCN06v2_RS11925	COG2205	protein histidine kinase activity
XCCCN06v2_RS11930	COG0784	Response regulator, receiver
XCCCN06v2_RS11930	COG2205	protein histidine kinase activity
XCCCN06v2_RS11930	COG2198	Histidine kinase
XCCCN06v2_RS11950	COG3279	Response regulator of the LytR AlgR family
XCCCN06v2_RS11970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCCCN06v2_RS11980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN06v2_RS11985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCCCN06v2_RS11995	COG0505	Belongs to the CarA family
XCCCN06v2_RS12005	COG2258	MOSC domain
XCCCN06v2_RS12010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN06v2_RS12035	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS12070	COG0277	FAD linked oxidase domain protein
XCCCN06v2_RS12075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN06v2_RS12090	COG0531	amino acid
XCCCN06v2_RS12095	COG0531	amino acid
XCCCN06v2_RS12125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCCCN06v2_RS12125	COG0140	phosphoribosyl-ATP diphosphatase activity
XCCCN06v2_RS12145	COG0131	Imidazoleglycerol-phosphate dehydratase
XCCCN06v2_RS12145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCCCN06v2_RS12175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN06v2_RS12185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCCCN06v2_RS12205	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCCCN06v2_RS12270	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN06v2_RS12295	COG0697	spore germination
XCCCN06v2_RS12300	COG1794	racemase activity, acting on amino acids and derivatives
XCCCN06v2_RS12310	COG0671	phosphoesterase, PA-phosphatase related
XCCCN06v2_RS12325	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCCCN06v2_RS12330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN06v2_RS12335	COG3706	GGDEF domain
XCCCN06v2_RS12335	COG2203	Gaf domain
XCCCN06v2_RS12335	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS12335	COG5001	Diguanylate cyclase
XCCCN06v2_RS12345	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN06v2_RS12400	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN06v2_RS12420	COG0477	Major facilitator Superfamily
XCCCN06v2_RS12430	COG1070	Carbohydrate kinase
XCCCN06v2_RS12440	COG1501	Belongs to the glycosyl hydrolase 31 family
XCCCN06v2_RS12480	COG0800	Aldolase
XCCCN06v2_RS12495	COG3734	2-keto-3-deoxy-galactonokinase
XCCCN06v2_RS12500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCCCN06v2_RS12510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN06v2_RS12525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCCCN06v2_RS12530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCCCN06v2_RS12540	COG0351	phosphomethylpyrimidine kinase
XCCCN06v2_RS12540	COG0352	thiamine-phosphate diphosphorylase activity
XCCCN06v2_RS12565	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS12570	COG1741	Belongs to the pirin family
XCCCN06v2_RS12605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN06v2_RS12615	COG4771	TonB-dependent receptor
XCCCN06v2_RS12625	COG1546	Belongs to the CinA family
XCCCN06v2_RS12645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCCCN06v2_RS12650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCCCN06v2_RS12660	COG1534	Rna-binding protein
XCCCN06v2_RS12675	COG1238	metal cluster binding
XCCCN06v2_RS12690	COG2840	Smr protein MutS2
XCCCN06v2_RS12750	COG2134	cdp-diacylglycerol pyrophosphatase
XCCCN06v2_RS12775	COG1253	flavin adenine dinucleotide binding
XCCCN06v2_RS12790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCCCN06v2_RS12795	COG0477	Major facilitator Superfamily
XCCCN06v2_RS12820	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS12825	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS12830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN06v2_RS12860	COG2244	polysaccharide biosynthetic process
XCCCN06v2_RS12875	COG3038	cytochrome b561
XCCCN06v2_RS12910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN06v2_RS12930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN06v2_RS12950	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCCCN06v2_RS13010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCCCN06v2_RS13155	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS13170	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCCCN06v2_RS13180	COG0077	Prephenate dehydratase
XCCCN06v2_RS13180	COG1605	Chorismate mutase
XCCCN06v2_RS13190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCCCN06v2_RS13245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCCCN06v2_RS13255	COG4993	Dehydrogenase
XCCCN06v2_RS13275	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCCCN06v2_RS13285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN06v2_RS13320	COG0316	Belongs to the HesB IscA family
XCCCN06v2_RS13325	COG0017	Asparaginyl-tRNA synthetase
XCCCN06v2_RS13350	COG0288	reversible hydration of carbon dioxide
XCCCN06v2_RS13375	COG2925	Exonuclease
XCCCN06v2_RS13390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCCCN06v2_RS13410	COG0488	(ABC) transporter
XCCCN06v2_RS13415	COG2264	protein methyltransferase activity
XCCCN06v2_RS13450	COG0494	nUDIX hydrolase
XCCCN06v2_RS13460	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS13470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCCCN06v2_RS13475	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN06v2_RS13500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCCCN06v2_RS13505	COG0573	inorganic phosphate transmembrane transporter activity
XCCCN06v2_RS13510	COG0581	inorganic phosphate transmembrane transporter activity
XCCCN06v2_RS13520	COG0704	Plays a role in the regulation of phosphate uptake
XCCCN06v2_RS13540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN06v2_RS13555	COG0557	exoribonuclease II activity
XCCCN06v2_RS13570	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS13575	COG2226	methyltransferase
XCCCN06v2_RS13580	COG0646	methionine synthase
XCCCN06v2_RS13580	COG1410	methionine synthase
XCCCN06v2_RS13585	COG1410	methionine synthase
XCCCN06v2_RS13585	COG0646	methionine synthase
XCCCN06v2_RS13595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN06v2_RS13605	COG1609	Transcriptional regulator
XCCCN06v2_RS13645	COG0386	Belongs to the glutathione peroxidase family
XCCCN06v2_RS13655	COG1725	Transcriptional regulator
XCCCN06v2_RS13660	COG1131	(ABC) transporter
XCCCN06v2_RS13690	COG1253	flavin adenine dinucleotide binding
XCCCN06v2_RS13710	COG2850	peptidyl-arginine hydroxylation
XCCCN06v2_RS13745	COG1132	(ABC) transporter
XCCCN06v2_RS13750	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS13755	COG2274	protein secretion by the type I secretion system
XCCCN06v2_RS13780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCCCN06v2_RS13800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCCCN06v2_RS13805	COG1420	regulation of RNA biosynthetic process
XCCCN06v2_RS13810	COG0497	DNA recombination
XCCCN06v2_RS13820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN06v2_RS13840	COG1404	Belongs to the peptidase S8 family
XCCCN06v2_RS13860	COG3706	GGDEF domain
XCCCN06v2_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS13890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN06v2_RS13900	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS13910	COG0415	Belongs to the DNA photolyase family
XCCCN06v2_RS13915	COG0305	Participates in initiation and elongation during chromosome replication
XCCCN06v2_RS13925	COG0367	asparagine synthase
XCCCN06v2_RS13940	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS13955	COG0084	hydrolase, TatD family'
XCCCN06v2_RS13960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCCCN06v2_RS14020	COG0386	Belongs to the glutathione peroxidase family
XCCCN06v2_RS14025	COG0339	signal peptide processing
XCCCN06v2_RS14060	COG3104	oligopeptide transport
XCCCN06v2_RS14090	COG2814	Major facilitator Superfamily
XCCCN06v2_RS14095	COG1566	PFAM secretion protein HlyD family protein
XCCCN06v2_RS14135	COG4774	siderophore transport
XCCCN06v2_RS14145	COG0367	asparagine synthase
XCCCN06v2_RS14160	COG1393	Belongs to the ArsC family
XCCCN06v2_RS14230	COG0528	UMP kinase activity
XCCCN06v2_RS14240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCCCN06v2_RS14245	COG0575	Belongs to the CDS family
XCCCN06v2_RS14255	COG0750	zinc metalloprotease
XCCCN06v2_RS14310	COG1981	membrane
XCCCN06v2_RS14335	COG1695	Transcriptional regulator
XCCCN06v2_RS14365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN06v2_RS14375	COG2040	homocysteine
XCCCN06v2_RS14380	COG0833	amino acid
XCCCN06v2_RS14385	COG0346	lactoylglutathione lyase activity
XCCCN06v2_RS14410	COG2878	Part of a membrane complex involved in electron transport
XCCCN06v2_RS14425	COG1595	DNA-templated transcription, initiation
XCCCN06v2_RS14450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN06v2_RS14465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN06v2_RS14470	COG0251	oxidation-reduction process
XCCCN06v2_RS14480	COG0392	lysyltransferase activity
XCCCN06v2_RS14480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCCCN06v2_RS14515	COG2814	Major facilitator Superfamily
XCCCN06v2_RS14520	COG1902	pentaerythritol trinitrate reductase activity
XCCCN06v2_RS14540	COG2824	Alkylphosphonate utilization operon protein PhnA
XCCCN06v2_RS14550	COG1047	Peptidyl-prolyl cis-trans
XCCCN06v2_RS14600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCCCN06v2_RS14610	COG5487	UPF0391 membrane protein
XCCCN06v2_RS14615	COG1451	nucleotide metabolic process
XCCCN06v2_RS14635	COG0183	Belongs to the thiolase family
XCCCN06v2_RS14670	COG1793	dna ligase
XCCCN06v2_RS14670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCCCN06v2_RS14680	COG1793	dna ligase
XCCCN06v2_RS14685	COG1201	RNA secondary structure unwinding
XCCCN06v2_RS14695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN06v2_RS14700	COG1278	Cold shock
XCCCN06v2_RS14705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCCCN06v2_RS14710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCCCN06v2_RS14720	COG3046	protein related to deoxyribodipyrimidine photolyase
XCCCN06v2_RS14725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN06v2_RS14725	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCCCN06v2_RS14730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCCCN06v2_RS14735	COG2954	triphosphatase activity
XCCCN06v2_RS14785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN06v2_RS14820	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS14825	COG1960	acyl-CoA dehydrogenase activity
XCCCN06v2_RS14835	COG3800	Transcriptional regulator
XCCCN06v2_RS14835	COG1396	sequence-specific DNA binding
XCCCN06v2_RS14845	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCCCN06v2_RS14850	COG3250	beta-galactosidase activity
XCCCN06v2_RS14980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCCCN06v2_RS15035	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN06v2_RS15065	COG3039	Transposase
XCCCN06v2_RS15085	COG1309	transcriptional regulator
XCCCN06v2_RS15090	COG0436	Aminotransferase
XCCCN06v2_RS15100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN06v2_RS15115	COG3483	tryptophan 2,3-dioxygenase activity
XCCCN06v2_RS15125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCCCN06v2_RS15145	COG0534	Mate efflux family protein
XCCCN06v2_RS15175	COG2070	2-Nitropropane dioxygenase
XCCCN06v2_RS15190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCCCN06v2_RS15195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN06v2_RS15205	COG3534	alpha-L-arabinofuranosidase
XCCCN06v2_RS15235	COG4191	Histidine kinase
XCCCN06v2_RS15235	COG0784	Response regulator, receiver
XCCCN06v2_RS15240	COG3850	Histidine kinase
XCCCN06v2_RS15240	COG3437	response regulator, receiver
XCCCN06v2_RS15240	COG4999	Histidine kinase
XCCCN06v2_RS15240	COG2205	protein histidine kinase activity
XCCCN06v2_RS15245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN06v2_RS15255	COG2205	protein histidine kinase activity
XCCCN06v2_RS15260	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCCCN06v2_RS15270	COG4771	TonB-dependent receptor
XCCCN06v2_RS15295	COG2172	sigma factor antagonist activity
XCCCN06v2_RS15300	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN06v2_RS15305	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN06v2_RS15310	COG1902	pentaerythritol trinitrate reductase activity
XCCCN06v2_RS15320	COG0326	Molecular chaperone. Has ATPase activity
XCCCN06v2_RS15325	COG2207	Transcriptional regulator
XCCCN06v2_RS15335	COG3152	Membrane
XCCCN06v2_RS15350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCCCN06v2_RS15355	COG1845	cytochrome c oxidase, subunit III
XCCCN06v2_RS15360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCCCN06v2_RS15390	COG0196	riboflavin kinase activity
XCCCN06v2_RS15420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCCCN06v2_RS15425	COG0824	Thioesterase
XCCCN06v2_RS15430	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS15435	COG1946	Acyl-CoA thioesterase
XCCCN06v2_RS15510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN06v2_RS15535	COG2197	response regulator
XCCCN06v2_RS15555	COG2894	cell division
XCCCN06v2_RS15570	COG5002	protein histidine kinase activity
XCCCN06v2_RS15575	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS15590	COG2194	sulfuric ester hydrolase activity
XCCCN06v2_RS15610	COG2814	Major facilitator Superfamily
XCCCN06v2_RS15630	COG0656	L-ascorbic acid biosynthetic process
XCCCN06v2_RS15635	COG0753	catalase activity
XCCCN06v2_RS15650	COG1917	Cupin 2, conserved barrel domain protein
XCCCN06v2_RS15650	COG2207	Transcriptional regulator
XCCCN06v2_RS15670	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN06v2_RS15670	COG1506	peptidase
XCCCN06v2_RS15680	COG1297	OPT oligopeptide transporter protein
XCCCN06v2_RS15705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN06v2_RS15730	COG2080	2 iron, 2 sulfur cluster binding
XCCCN06v2_RS15735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN06v2_RS15740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN06v2_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS15790	COG3537	Alpha-1,2-mannosidase
XCCCN06v2_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS15805	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN06v2_RS15820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN06v2_RS15855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN06v2_RS15870	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XCCCN06v2_RS15920	COG0308	aminopeptidase N
XCCCN06v2_RS15935	COG0330	HflC and HflK could
XCCCN06v2_RS15940	COG0330	HflC and HflK could
XCCCN06v2_RS15960	COG0678	peroxiredoxin activity
XCCCN06v2_RS15970	COG4953	penicillin-binding protein 1C
XCCCN06v2_RS15995	COG2373	Large extracellular alpha-helical protein
XCCCN06v2_RS16025	COG3609	addiction module antidote protein, CC2985 family
XCCCN06v2_RS16045	COG3829	transcription factor binding
XCCCN06v2_RS16160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCCCN06v2_RS16165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCCCN06v2_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS16185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCCCN06v2_RS16190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN06v2_RS16200	COG1399	metal-binding, possibly nucleic acid-binding protein
XCCCN06v2_RS16230	COG0714	Associated with various cellular activities
XCCCN06v2_RS16250	COG0537	adenosine 5'-monophosphoramidase activity
XCCCN06v2_RS16315	COG2003	Belongs to the UPF0758 family
XCCCN06v2_RS16355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XCCCN06v2_RS16355	COG4191	Histidine kinase
XCCCN06v2_RS16395	COG0314	molybdopterin synthase activity
XCCCN06v2_RS16400	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCCCN06v2_RS16420	COG1234	tRNA 3'-trailer cleavage
XCCCN06v2_RS16430	COG0859	PFAM glycosyl transferase family 9
XCCCN06v2_RS16445	COG0631	protein serine/threonine phosphatase activity
XCCCN06v2_RS16450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCCCN06v2_RS16550	COG0473	3-isopropylmalate dehydrogenase activity
XCCCN06v2_RS16565	COG4783	chaperone-mediated protein folding
XCCCN06v2_RS16570	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS16580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCCCN06v2_RS16590	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS16595	COG0671	phosphoesterase, PA-phosphatase related
XCCCN06v2_RS16600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCCCN06v2_RS16610	COG3291	Pkd domain containing protein
XCCCN06v2_RS16615	COG2833	Protein of unknown function (DUF455)
XCCCN06v2_RS16635	COG0285	dihydrofolate synthase activity
XCCCN06v2_RS16650	COG0406	alpha-ribazole phosphatase activity
XCCCN06v2_RS16675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCCCN06v2_RS16680	COG4208	sulfate ABC transporter
XCCCN06v2_RS16685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCCCN06v2_RS16690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCCCN06v2_RS16725	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCCCN06v2_RS16725	COG1902	pentaerythritol trinitrate reductase activity
XCCCN06v2_RS16745	COG0625	glutathione transferase activity
XCCCN06v2_RS16755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCCCN06v2_RS16760	COG1217	gtp-binding protein TYPA
XCCCN06v2_RS16770	COG0154	amidase activity
XCCCN06v2_RS16780	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCCCN06v2_RS16815	COG0201	protein transport
XCCCN06v2_RS16900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCCCN06v2_RS16970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCCCN06v2_RS16975	COG0250	Participates in transcription elongation, termination and antitermination
XCCCN06v2_RS16980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XCCCN06v2_RS17010	COG0012	GTP binding
XCCCN06v2_RS17015	COG0193	aminoacyl-tRNA hydrolase activity
XCCCN06v2_RS17025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCCCN06v2_RS17065	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCCCN06v2_RS17085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN06v2_RS17115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCCCN06v2_RS17120	COG1404	Belongs to the peptidase S8 family
XCCCN06v2_RS17125	COG1404	Belongs to the peptidase S8 family
XCCCN06v2_RS17130	COG1404	Belongs to the peptidase S8 family
XCCCN06v2_RS17135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCCCN06v2_RS17200	COG0778	Nitroreductase
XCCCN06v2_RS17205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN06v2_RS17205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN06v2_RS17230	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN06v2_RS17240	COG3634	alkyl hydroperoxide reductase activity
XCCCN06v2_RS17245	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS17250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN06v2_RS17275	COG2197	response regulator
XCCCN06v2_RS17280	COG0784	Response regulator, receiver
XCCCN06v2_RS17280	COG2205	protein histidine kinase activity
XCCCN06v2_RS17280	COG5002	protein histidine kinase activity
XCCCN06v2_RS17310	COG0697	spore germination
XCCCN06v2_RS17340	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN06v2_RS17360	COG1024	Enoyl-CoA hydratase
XCCCN06v2_RS17370	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN06v2_RS17375	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS17380	COG3384	dioxygenase
XCCCN06v2_RS17410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN06v2_RS17415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN06v2_RS17425	COG2096	Adenosyltransferase
XCCCN06v2_RS17430	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCCCN06v2_RS17460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCCCN06v2_RS17495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCCCN06v2_RS17505	COG0642	Histidine kinase
XCCCN06v2_RS17520	COG4181	ATPase activity
XCCCN06v2_RS17530	COG2175	clavaminate synthase activity
XCCCN06v2_RS17540	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCCCN06v2_RS17565	COG4771	TonB-dependent receptor
XCCCN06v2_RS17575	COG0667	Aldo Keto reductase
XCCCN06v2_RS17580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCCCN06v2_RS17590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN06v2_RS17685	COG0366	Alpha amylase catalytic
XCCCN06v2_RS17720	COG3321	synthase
XCCCN06v2_RS17720	COG0604	alcohol dehydrogenase
XCCCN06v2_RS17720	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS17735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN06v2_RS17750	COG0494	nUDIX hydrolase
XCCCN06v2_RS17765	COG0739	heme binding
XCCCN06v2_RS17790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCCCN06v2_RS17795	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN06v2_RS17820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCCCN06v2_RS17835	COG3116	cell division
XCCCN06v2_RS17895	COG1988	membrane-bound metal-dependent
XCCCN06v2_RS17900	COG0277	FAD linked oxidase domain protein
XCCCN06v2_RS17910	COG0745	RESPONSE REGULATOR receiver
XCCCN06v2_RS17915	COG2205	protein histidine kinase activity
XCCCN06v2_RS17925	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCCCN06v2_RS17930	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCCCN06v2_RS17945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCCCN06v2_RS17975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN06v2_RS17975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN06v2_RS18000	COG0488	(ABC) transporter
XCCCN06v2_RS18005	COG0242	peptide deformylase activity
XCCCN06v2_RS18010	COG1393	Belongs to the ArsC family
XCCCN06v2_RS18080	COG2188	Transcriptional regulator
XCCCN06v2_RS18095	COG1450	Type ii and iii secretion system protein
XCCCN06v2_RS18110	COG3166	PFAM Fimbrial assembly family protein
XCCCN06v2_RS18115	COG3156	type II secretion system protein K
XCCCN06v2_RS18120	COG4795	General secretion pathway protein
XCCCN06v2_RS18125	COG2165	general secretion pathway protein
XCCCN06v2_RS18130	COG4970	Tfp pilus assembly protein FimT
XCCCN06v2_RS18135	COG2165	general secretion pathway protein
XCCCN06v2_RS18140	COG1459	type II secretion system
XCCCN06v2_RS18145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN06v2_RS18150	COG1404	Belongs to the peptidase S8 family
XCCCN06v2_RS18165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCCCN06v2_RS18165	COG0047	phosphoribosylformylglycinamidine synthase activity
XCCCN06v2_RS18170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN06v2_RS18175	COG4974	Belongs to the 'phage' integrase family
XCCCN06v2_RS18190	COG0795	lipopolysaccharide-transporting ATPase activity
XCCCN06v2_RS18260	COG1183	phosphatidylcholine synthase activity
XCCCN06v2_RS18285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN06v2_RS18290	COG1127	ABC transporter
XCCCN06v2_RS18295	COG3218	ABC-type transport auxiliary lipoprotein component
XCCCN06v2_RS18295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN06v2_RS18335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCCCN06v2_RS18340	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN06v2_RS18340	COG0662	Cupin 2, conserved barrel domain protein
XCCCN06v2_RS18365	COG2086	electron transfer activity
XCCCN06v2_RS18375	COG0662	Cupin 2, conserved barrel domain protein
XCCCN06v2_RS18375	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN06v2_RS18385	COG0463	Glycosyl transferase, family 2
XCCCN06v2_RS18410	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCCCN06v2_RS18425	COG0438	transferase activity, transferring glycosyl groups
XCCCN06v2_RS18450	COG0626	cystathionine gamma-synthase activity
XCCCN06v2_RS18480	COG0625	glutathione transferase activity
XCCCN06v2_RS18490	COG0513	Belongs to the DEAD box helicase family
XCCCN06v2_RS18495	COG0720	synthase
XCCCN06v2_RS18510	COG1956	GAF domain-containing protein
XCCCN06v2_RS18540	COG0339	signal peptide processing
XCCCN06v2_RS18545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCCCN06v2_RS18600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN06v2_RS18610	COG1136	(ABC) transporter
XCCCN06v2_RS18615	COG0577	efflux transmembrane transporter activity
XCCCN06v2_RS18635	COG4191	Histidine kinase
XCCCN06v2_RS18700	COG0356	it plays a direct role in the translocation of protons across the membrane
XCCCN06v2_RS18715	COG1228	amidohydrolase
XCCCN06v2_RS18720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN06v2_RS18730	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN06v2_RS18760	COG2011	ABC-type metal ion transport system permease component
XCCCN06v2_RS18770	COG0697	spore germination
XCCCN06v2_RS18800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN06v2_RS18805	COG1187	pseudouridine synthase activity
XCCCN06v2_RS18810	COG2813	Specifically methylates the guanine in position
XCCCN06v2_RS18830	COG5002	protein histidine kinase activity
XCCCN06v2_RS18910	COG0842	Transport permease protein
XCCCN06v2_RS18915	COG1131	(ABC) transporter
XCCCN06v2_RS18920	COG0025	NhaP-type Na H and K H
XCCCN06v2_RS18925	COG3795	YCII-related domain
XCCCN06v2_RS18930	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCCCN06v2_RS18935	COG1573	uracil-dna glycosylase
XCCCN06v2_RS18945	COG3384	dioxygenase
XCCCN06v2_RS18950	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS18960	COG0667	Aldo Keto reductase
XCCCN06v2_RS18970	COG3590	peptidase
XCCCN06v2_RS18985	COG0531	amino acid
XCCCN06v2_RS19000	COG2972	Histidine kinase
XCCCN06v2_RS19025	COG1335	isochorismatase
XCCCN06v2_RS19035	COG3685	Protein conserved in bacteria
XCCCN06v2_RS19040	COG3546	catalase activity
XCCCN06v2_RS19070	COG2204	response regulator
XCCCN06v2_RS19080	COG1271	oxidase subunit
XCCCN06v2_RS19085	COG1294	oxidase, subunit
XCCCN06v2_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS19105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCCCN06v2_RS19125	COG1132	(ABC) transporter
XCCCN06v2_RS19140	COG1063	alcohol dehydrogenase
XCCCN06v2_RS19180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN06v2_RS19240	COG0251	oxidation-reduction process
XCCCN06v2_RS19260	COG0667	Aldo Keto reductase
XCCCN06v2_RS19265	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS19285	COG3706	GGDEF domain
XCCCN06v2_RS19285	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS19285	COG5001	Diguanylate cyclase
XCCCN06v2_RS19285	COG2203	Gaf domain
XCCCN06v2_RS19315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN06v2_RS19325	COG1560	Kdo2-lipid A biosynthetic process
XCCCN06v2_RS19335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCCCN06v2_RS19370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCCCN06v2_RS19370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCCCN06v2_RS19380	COG0242	peptide deformylase activity
XCCCN06v2_RS19385	COG1652	LysM domain
XCCCN06v2_RS19390	COG0758	DNA mediated transformation
XCCCN06v2_RS19410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN06v2_RS19410	COG1754	DNA topoisomerase type I activity
XCCCN06v2_RS19430	COG2203	Gaf domain
XCCCN06v2_RS19430	COG5001	Diguanylate cyclase
XCCCN06v2_RS19430	COG4251	negative regulation of phosphorylation
XCCCN06v2_RS19430	COG3706	GGDEF domain
XCCCN06v2_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS19445	COG0616	signal peptide processing
XCCCN06v2_RS19450	COG0534	Mate efflux family protein
XCCCN06v2_RS19465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCCCN06v2_RS19485	COG1252	NADH dehydrogenase
XCCCN06v2_RS19490	COG2860	membrane
XCCCN06v2_RS19495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN06v2_RS19505	COG2201	protein-glutamate methylesterase activity
XCCCN06v2_RS19510	COG2177	Part of the ABC transporter FtsEX involved in
XCCCN06v2_RS19515	COG2884	Cell division ATP-binding protein ftsE
XCCCN06v2_RS19525	COG3118	belongs to the thioredoxin family
XCCCN06v2_RS19530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCCCN06v2_RS19575	COG1473	amidohydrolase
XCCCN06v2_RS19580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN06v2_RS19610	COG4941	Belongs to the sigma-70 factor family
XCCCN06v2_RS19615	COG5383	Protein conserved in bacteria
XCCCN06v2_RS19655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCCCN06v2_RS19660	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN06v2_RS19660	COG3501	Rhs element vgr protein
XCCCN06v2_RS19675	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCCCN06v2_RS19685	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN06v2_RS19695	COG0531	amino acid
XCCCN06v2_RS19710	COG4682	membrane
XCCCN06v2_RS19715	COG2133	pyrroloquinoline quinone binding
XCCCN06v2_RS19725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCCCN06v2_RS19740	COG1610	YqeY-like protein
XCCCN06v2_RS19745	COG1295	ribonuclease BN
XCCCN06v2_RS19750	COG0358	DNA primase activity
XCCCN06v2_RS19800	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCCCN06v2_RS19815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCCCN06v2_RS19860	COG0739	heme binding
XCCCN06v2_RS19875	COG2223	nitrite transmembrane transporter activity
XCCCN06v2_RS19885	COG0708	Exodeoxyribonuclease III
XCCCN06v2_RS19900	COG1192	Involved in chromosome partitioning
XCCCN06v2_RS19905	COG1475	DNA binding
XCCCN06v2_RS19925	COG0463	Glycosyl transferase, family 2
XCCCN06v2_RS19950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCCCN06v2_RS19975	COG4221	oxidoreductase activity
XCCCN06v2_RS19980	COG2755	lipolytic protein G-D-S-L family
XCCCN06v2_RS19980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCCCN06v2_RS19995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCCCN06v2_RS20000	COG1166	arginine decarboxylase activity
XCCCN06v2_RS20025	COG2960	long-chain fatty acid transporting porin activity
XCCCN06v2_RS20030	COG0606	chelatase, subunit chli
XCCCN06v2_RS20045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCCCN06v2_RS20090	COG1690	Belongs to the RtcB family
XCCCN06v2_RS20135	COG1090	epimerase
XCCCN06v2_RS20140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN06v2_RS20155	COG0642	Histidine kinase
XCCCN06v2_RS20175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN06v2_RS20200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN06v2_RS20205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCCCN06v2_RS20225	COG2197	response regulator
XCCCN06v2_RS20230	COG4585	Histidine kinase
XCCCN06v2_RS20245	COG1136	(ABC) transporter
XCCCN06v2_RS20270	COG0697	spore germination
XCCCN06v2_RS20295	COG0180	Tryptophanyl-tRNA synthetase
XCCCN06v2_RS20300	COG3237	CsbD-like
XCCCN06v2_RS20375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCCCN06v2_RS20375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCCCN06v2_RS20415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN06v2_RS20445	COG1199	ATP-dependent helicase activity
XCCCN06v2_RS20510	COG0625	glutathione transferase activity
XCCCN06v2_RS20545	COG4555	ABC transporter
XCCCN06v2_RS20555	COG1476	TRANSCRIPTIONal
XCCCN06v2_RS20570	COG1230	cation diffusion facilitator family transporter
XCCCN06v2_RS20580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN06v2_RS20585	COG1131	(ABC) transporter
XCCCN06v2_RS20590	COG0842	Transport permease protein
XCCCN06v2_RS20600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCCCN06v2_RS20615	COG1607	acyl-coa hydrolase
XCCCN06v2_RS20625	COG0716	FMN binding
XCCCN06v2_RS20630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN06v2_RS20645	COG0045	succinate-CoA ligase (ADP-forming) activity
XCCCN06v2_RS20645	COG1042	CoA-binding domain protein
XCCCN06v2_RS20645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCCCN06v2_RS20655	COG2239	Acts as a magnesium transporter
XCCCN06v2_RS20670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN06v2_RS20675	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN06v2_RS20695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCCCN06v2_RS20705	COG0463	Glycosyl transferase, family 2
XCCCN06v2_RS20720	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS20765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCCCN06v2_RS20835	COG0210	DNA helicase
XCCCN06v2_RS20845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN06v2_RS20850	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS20855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCCCN06v2_RS20865	COG2159	amidohydrolase
XCCCN06v2_RS20925	COG3540	Alkaline phosphatase
XCCCN06v2_RS20935	COG2826	transposase and inactivated derivatives, IS30 family
XCCCN06v2_RS20975	COG2091	lysine biosynthetic process via aminoadipic acid
XCCCN06v2_RS21035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCCCN06v2_RS21045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCCCN06v2_RS21050	COG3162	membrane
XCCCN06v2_RS21085	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN06v2_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN06v2_RS21105	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCCCN06v2_RS21110	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN06v2_RS21120	COG3254	rhamnose metabolic process
XCCCN06v2_RS21130	COG1414	Transcriptional regulator
XCCCN06v2_RS21150	COG0784	Response regulator, receiver
XCCCN06v2_RS21150	COG2205	protein histidine kinase activity
XCCCN06v2_RS21155	COG3459	Glycosyltransferase 36 associated
XCCCN06v2_RS21160	COG2211	Major facilitator Superfamily
XCCCN06v2_RS21165	COG3265	gluconokinase activity
XCCCN06v2_RS21170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN06v2_RS21190	COG2911	Protein conserved in bacteria
XCCCN06v2_RS21195	COG0729	surface antigen
XCCCN06v2_RS21210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN06v2_RS21215	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN06v2_RS21215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCCCN06v2_RS21230	COG0805	protein transport
XCCCN06v2_RS21250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCCCN06v2_RS21295	COG3661	Belongs to the glycosyl hydrolase 67 family
XCCCN06v2_RS21305	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN06v2_RS21315	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN06v2_RS21320	COG0246	Mannitol dehydrogenase
XCCCN06v2_RS21350	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN06v2_RS21370	COG3250	beta-galactosidase activity
XCCCN06v2_RS21380	COG3693	PFAM glycoside hydrolase, family 10
XCCCN06v2_RS21395	COG2211	Major facilitator Superfamily
XCCCN06v2_RS21435	COG2937	Belongs to the GPAT DAPAT family
XCCCN06v2_RS21470	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCCCN06v2_RS21490	COG0210	DNA helicase
XCCCN06v2_RS21520	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCCCN06v2_RS21565	COG3135	benzoate transporter
XCCCN06v2_RS21590	COG0676	glucose-6-phosphate 1-epimerase activity
XCCCN06v2_RS21610	COG0730	response to heat
XCCCN06v2_RS21640	COG0302	gtp cyclohydrolase
XCCCN06v2_RS21655	COG1566	PFAM secretion protein HlyD family protein
XCCCN06v2_RS21665	COG1289	transmembrane transporter activity
XCCCN06v2_RS21670	COG0477	Major facilitator Superfamily
XCCCN06v2_RS21680	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS21690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN06v2_RS21710	COG1487	ribonuclease activity
XCCCN06v2_RS21765	COG0564	pseudouridine synthase activity
XCCCN06v2_RS21815	COG1074	ATP-dependent DNA helicase activity
XCCCN06v2_RS21820	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCCCN06v2_RS21855	COG1127	ABC transporter
XCCCN06v2_RS21860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN06v2_RS21865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN06v2_RS21880	COG2853	Lipoprotein
XCCCN06v2_RS21890	COG0386	Belongs to the glutathione peroxidase family
XCCCN06v2_RS21900	COG1322	Protein conserved in bacteria
XCCCN06v2_RS21910	COG0604	alcohol dehydrogenase
XCCCN06v2_RS21915	COG0583	DNA-binding transcription factor activity
XCCCN06v2_RS21930	COG0531	amino acid
XCCCN06v2_RS21940	COG4206	TonB-dependent receptor
XCCCN06v2_RS21950	COG3706	GGDEF domain
XCCCN06v2_RS21955	COG3835	regulator
XCCCN06v2_RS21960	COG1929	Belongs to the glycerate kinase type-1 family
XCCCN06v2_RS21990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCCCN06v2_RS21995	COG0861	Integral membrane protein TerC family
XCCCN06v2_RS22020	COG0584	glycerophosphoryl diester phosphodiesterase
XCCCN06v2_RS22035	COG0671	phosphoesterase, PA-phosphatase related
XCCCN06v2_RS22050	COG0726	polysaccharide deacetylase
XCCCN06v2_RS22055	COG0706	membrane insertase activity
XCCCN06v2_RS22070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN06v2_RS22095	COG3039	Transposase
XCCCN06v2_RS22125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN06v2_RS22160	COG3846	protein secretion by the type IV secretion system
XCCCN06v2_RS22175	COG3451	type IV secretory pathway VirB4
XCCCN06v2_RS22190	COG4962	Type ii secretion system protein e
XCCCN06v2_RS22385	COG0489	protein tyrosine kinase activity