locus-tag	class	description
XCCCN07v2_RS00020	COG0187	DNA topoisomerase II activity
XCCCN07v2_RS00030	COG0501	Belongs to the peptidase M48B family
XCCCN07v2_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN07v2_RS00105	COG0793	Belongs to the peptidase S41A family
XCCCN07v2_RS00110	COG4942	peptidase
XCCCN07v2_RS00120	COG2234	aminopeptidase activity
XCCCN07v2_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN07v2_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN07v2_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN07v2_RS00150	COG1064	alcohol dehydrogenase
XCCCN07v2_RS00170	COG1733	regulation of RNA biosynthetic process
XCCCN07v2_RS00180	COG2249	NAD(P)H dehydrogenase (quinone) activity
XCCCN07v2_RS00205	COG1272	protein, Hemolysin III
XCCCN07v2_RS00210	COG3177	Filamentation induced by cAMP protein fic
XCCCN07v2_RS00215	COG1205	dead DEAH box helicase
XCCCN07v2_RS00215	COG1111	helicase
XCCCN07v2_RS00275	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS00300	COG1741	Belongs to the pirin family
XCCCN07v2_RS00310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCCCN07v2_RS00325	COG0067	glutamate synthase
XCCCN07v2_RS00325	COG0069	glutamate synthase activity
XCCCN07v2_RS00325	COG0070	glutamate synthase
XCCCN07v2_RS00330	COG0493	'glutamate synthase
XCCCN07v2_RS00390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XCCCN07v2_RS00395	COG3237	CsbD-like
XCCCN07v2_RS00440	COG0628	permease
XCCCN07v2_RS00445	COG0657	acetylesterase activity
XCCCN07v2_RS00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN07v2_RS00460	COG0477	Major facilitator Superfamily
XCCCN07v2_RS00500	COG0714	Associated with various cellular activities
XCCCN07v2_RS00545	COG4772	TonB-dependent receptor
XCCCN07v2_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN07v2_RS00595	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCCCN07v2_RS00600	COG4585	Histidine kinase
XCCCN07v2_RS00605	COG2197	response regulator
XCCCN07v2_RS00640	COG3710	Transcriptional regulator
XCCCN07v2_RS00660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN07v2_RS00690	COG4916	TIR domain
XCCCN07v2_RS00705	COG1192	Involved in chromosome partitioning
XCCCN07v2_RS00780	COG3039	Transposase
XCCCN07v2_RS00790	COG0366	Alpha amylase catalytic
XCCCN07v2_RS00795	COG0366	Alpha amylase catalytic
XCCCN07v2_RS00845	COG2755	lipolytic protein G-D-S-L family
XCCCN07v2_RS00855	COG0657	acetylesterase activity
XCCCN07v2_RS00855	COG2755	lipolytic protein G-D-S-L family
XCCCN07v2_RS00865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCCCN07v2_RS00880	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN07v2_RS00885	COG1609	Transcriptional regulator
XCCCN07v2_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS00905	COG2755	lipolytic protein G-D-S-L family
XCCCN07v2_RS00915	COG3186	Phenylalanine-4-hydroxylase
XCCCN07v2_RS00920	COG1522	sequence-specific DNA binding
XCCCN07v2_RS00935	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCCCN07v2_RS00945	COG1119	ATPase activity
XCCCN07v2_RS00960	COG0517	IMP dehydrogenase activity
XCCCN07v2_RS00960	COG1125	glycine betaine transport
XCCCN07v2_RS00975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN07v2_RS00980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCCCN07v2_RS01010	COG0489	protein tyrosine kinase activity
XCCCN07v2_RS01015	COG0588	phosphoglycerate mutase activity
XCCCN07v2_RS01025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS01050	COG1881	PFAM PEBP family protein
XCCCN07v2_RS01065	COG0174	glutamine synthetase
XCCCN07v2_RS01070	COG0347	Belongs to the P(II) protein family
XCCCN07v2_RS01075	COG0004	ammonium transporteR
XCCCN07v2_RS01080	COG3852	Histidine kinase
XCCCN07v2_RS01085	COG2204	response regulator
XCCCN07v2_RS01095	COG2032	superoxide dismutase activity
XCCCN07v2_RS01100	COG2032	superoxide dismutase activity
XCCCN07v2_RS01105	COG0346	lactoylglutathione lyase activity
XCCCN07v2_RS01115	COG0183	Belongs to the thiolase family
XCCCN07v2_RS01150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCCCN07v2_RS01170	COG0028	Belongs to the TPP enzyme family
XCCCN07v2_RS01185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCCCN07v2_RS01200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN07v2_RS01205	COG3177	Filamentation induced by cAMP protein fic
XCCCN07v2_RS01220	COG0596	Alpha beta hydrolase
XCCCN07v2_RS01225	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCCCN07v2_RS01230	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN07v2_RS01235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN07v2_RS01250	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN07v2_RS01265	COG0564	pseudouridine synthase activity
XCCCN07v2_RS01285	COG1446	asparaginase
XCCCN07v2_RS01290	COG0339	signal peptide processing
XCCCN07v2_RS01320	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS01325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCCCN07v2_RS01330	COG2224	Isocitrate lyase
XCCCN07v2_RS01360	COG4770	biotin carboxylase activity
XCCCN07v2_RS01365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCCCN07v2_RS01370	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS01435	COG0697	spore germination
XCCCN07v2_RS01445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCCCN07v2_RS01455	COG1846	Transcriptional regulator
XCCCN07v2_RS01460	COG1764	response to oxidative stress
XCCCN07v2_RS01490	COG0656	L-ascorbic acid biosynthetic process
XCCCN07v2_RS01495	COG2130	NADP-dependent
XCCCN07v2_RS01510	COG1187	pseudouridine synthase activity
XCCCN07v2_RS01520	COG1643	Atp-dependent helicase
XCCCN07v2_RS01525	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS01530	COG4807	Protein conserved in bacteria
XCCCN07v2_RS01535	COG2351	hydroxyisourate hydrolase activity
XCCCN07v2_RS01540	COG2072	flavoprotein involved in K transport
XCCCN07v2_RS01560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCCCN07v2_RS01590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS01605	COG1957	nucleoside hydrolase
XCCCN07v2_RS01615	COG2252	PERMEase
XCCCN07v2_RS01635	COG0084	hydrolase, TatD family'
XCCCN07v2_RS01645	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS01650	COG2814	Major facilitator Superfamily
XCCCN07v2_RS01675	COG1902	pentaerythritol trinitrate reductase activity
XCCCN07v2_RS01700	COG0300	oxidoreductase activity
XCCCN07v2_RS01710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN07v2_RS01715	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS01745	COG0702	epimerase
XCCCN07v2_RS01750	COG1733	regulation of RNA biosynthetic process
XCCCN07v2_RS01760	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS01895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCCCN07v2_RS01955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCCCN07v2_RS01980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN07v2_RS01985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN07v2_RS01995	COG3485	protocatechuate 3,4-dioxygenase
XCCCN07v2_RS02000	COG3485	protocatechuate 3,4-dioxygenase
XCCCN07v2_RS02010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN07v2_RS02015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCCCN07v2_RS02025	COG1414	Transcriptional regulator
XCCCN07v2_RS02035	COG0657	acetylesterase activity
XCCCN07v2_RS02055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCCCN07v2_RS02105	COG1040	competence protein
XCCCN07v2_RS02120	COG0582	viral genome integration into host DNA
XCCCN07v2_RS02130	COG4774	siderophore transport
XCCCN07v2_RS02135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN07v2_RS02150	COG4206	TonB-dependent receptor
XCCCN07v2_RS02170	COG3264	Mechanosensitive ion channel
XCCCN07v2_RS02170	COG1511	domain protein
XCCCN07v2_RS02175	COG1368	sulfuric ester hydrolase activity
XCCCN07v2_RS02180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCCCN07v2_RS02185	COG2354	Protein conserved in bacteria
XCCCN07v2_RS02190	COG1649	PFAM Uncharacterised BCR, COG1649
XCCCN07v2_RS02200	COG0297	glycogen (starch) synthase activity
XCCCN07v2_RS02210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCCCN07v2_RS02235	COG0702	epimerase
XCCCN07v2_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS02300	COG0513	Belongs to the DEAD box helicase family
XCCCN07v2_RS02325	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN07v2_RS02340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCCCN07v2_RS02355	COG3104	oligopeptide transport
XCCCN07v2_RS02375	COG2852	Protein conserved in bacteria
XCCCN07v2_RS02400	COG1320	monovalent cation:proton antiporter activity
XCCCN07v2_RS02405	COG2212	antiporter activity
XCCCN07v2_RS02415	COG0651	ATP synthesis coupled electron transport
XCCCN07v2_RS02420	COG1006	Multisubunit Na H antiporter MnhC subunit
XCCCN07v2_RS02425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCCCN07v2_RS02425	COG2111	Na H antiporter
XCCCN07v2_RS02500	COG0436	Aminotransferase
XCCCN07v2_RS02510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN07v2_RS02545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCCCN07v2_RS02655	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN07v2_RS02685	COG2814	Major facilitator Superfamily
XCCCN07v2_RS02695	COG1289	transmembrane transporter activity
XCCCN07v2_RS02700	COG0151	Belongs to the GarS family
XCCCN07v2_RS02715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN07v2_RS02720	COG2267	carboxylic ester hydrolase activity
XCCCN07v2_RS02725	COG2453	phosphatase
XCCCN07v2_RS02725	COG0671	phosphoesterase, PA-phosphatase related
XCCCN07v2_RS02750	COG4589	Belongs to the CDS family
XCCCN07v2_RS02765	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCCCN07v2_RS02800	COG0439	Biotin carboxylase
XCCCN07v2_RS02810	COG0511	ligase activity, forming carbon-carbon bonds
XCCCN07v2_RS02825	COG1324	tolerance protein
XCCCN07v2_RS02830	COG2356	endonuclease I
XCCCN07v2_RS02845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCCCN07v2_RS02860	COG1196	nuclear chromosome segregation
XCCCN07v2_RS02920	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN07v2_RS02935	COG3712	iron ion homeostasis
XCCCN07v2_RS02975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN07v2_RS03000	COG2353	YceI-like domain
XCCCN07v2_RS03130	COG3039	Transposase
XCCCN07v2_RS03160	COG3039	Transposase
XCCCN07v2_RS03200	COG3039	Transposase
XCCCN07v2_RS03215	COG3039	Transposase
XCCCN07v2_RS03250	COG0435	Glutathione S-transferase
XCCCN07v2_RS03310	COG2409	Drug exporters of the RND superfamily
XCCCN07v2_RS03320	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN07v2_RS03320	COG1506	peptidase
XCCCN07v2_RS03335	COG1959	2 iron, 2 sulfur cluster binding
XCCCN07v2_RS03370	COG0697	spore germination
XCCCN07v2_RS03385	COG4305	rare lipoprotein A
XCCCN07v2_RS03390	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN07v2_RS03400	COG1113	amino acid transport
XCCCN07v2_RS03465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN07v2_RS03465	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN07v2_RS03470	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN07v2_RS03490	COG3273	potassium ion transport
XCCCN07v2_RS03490	COG0471	metal ion transport
XCCCN07v2_RS03505	COG3275	phosphorelay sensor kinase activity
XCCCN07v2_RS03545	COG1505	serine-type exopeptidase activity
XCCCN07v2_RS03560	COG0436	Aminotransferase
XCCCN07v2_RS03570	COG2832	Protein of unknown function (DUF454)
XCCCN07v2_RS03615	COG0308	aminopeptidase N
XCCCN07v2_RS03620	COG5001	Diguanylate cyclase
XCCCN07v2_RS03620	COG3300	MHYT domain
XCCCN07v2_RS03625	COG2226	methyltransferase
XCCCN07v2_RS03700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCCCN07v2_RS03720	COG3284	Transcriptional regulator
XCCCN07v2_RS03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN07v2_RS03730	COG1077	Cell shape determining protein MreB Mrl
XCCCN07v2_RS03740	COG1792	Involved in formation and maintenance of cell shape
XCCCN07v2_RS03755	COG0772	Belongs to the SEDS family
XCCCN07v2_RS03780	COG0697	spore germination
XCCCN07v2_RS03790	COG1307	EDD domain protein, DegV family
XCCCN07v2_RS03830	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN07v2_RS03850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN07v2_RS03875	COG0366	Alpha amylase catalytic
XCCCN07v2_RS03970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN07v2_RS03980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCCCN07v2_RS03985	COG0667	Aldo Keto reductase
XCCCN07v2_RS04000	COG4771	TonB-dependent receptor
XCCCN07v2_RS04025	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCCCN07v2_RS04035	COG2175	clavaminate synthase activity
XCCCN07v2_RS04050	COG4181	ATPase activity
XCCCN07v2_RS04065	COG0642	Histidine kinase
XCCCN07v2_RS04075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCCCN07v2_RS04110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCCCN07v2_RS04140	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCCCN07v2_RS04145	COG2096	Adenosyltransferase
XCCCN07v2_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN07v2_RS04160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN07v2_RS04190	COG3384	dioxygenase
XCCCN07v2_RS04195	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS04200	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN07v2_RS04210	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS04230	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN07v2_RS04260	COG0697	spore germination
XCCCN07v2_RS04290	COG2205	protein histidine kinase activity
XCCCN07v2_RS04290	COG5002	protein histidine kinase activity
XCCCN07v2_RS04290	COG0784	Response regulator, receiver
XCCCN07v2_RS04295	COG2197	response regulator
XCCCN07v2_RS04320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN07v2_RS04325	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS04330	COG3634	alkyl hydroperoxide reductase activity
XCCCN07v2_RS04340	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN07v2_RS04360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN07v2_RS04360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN07v2_RS04365	COG0778	Nitroreductase
XCCCN07v2_RS04430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCCCN07v2_RS04435	COG1404	Belongs to the peptidase S8 family
XCCCN07v2_RS04445	COG1404	Belongs to the peptidase S8 family
XCCCN07v2_RS04450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCCCN07v2_RS04480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN07v2_RS04500	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCCCN07v2_RS04540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCCCN07v2_RS04550	COG0193	aminoacyl-tRNA hydrolase activity
XCCCN07v2_RS04555	COG0012	GTP binding
XCCCN07v2_RS04590	COG0250	Participates in transcription elongation, termination and antitermination
XCCCN07v2_RS04750	COG0201	protein transport
XCCCN07v2_RS04785	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCCCN07v2_RS04800	COG0154	amidase activity
XCCCN07v2_RS04810	COG1217	gtp-binding protein TYPA
XCCCN07v2_RS04815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCCCN07v2_RS04825	COG0625	glutathione transferase activity
XCCCN07v2_RS04845	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCCCN07v2_RS04845	COG1902	pentaerythritol trinitrate reductase activity
XCCCN07v2_RS04880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCCCN07v2_RS04885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCCCN07v2_RS04890	COG4208	sulfate ABC transporter
XCCCN07v2_RS04895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCCCN07v2_RS04920	COG0406	alpha-ribazole phosphatase activity
XCCCN07v2_RS04935	COG0285	dihydrofolate synthase activity
XCCCN07v2_RS04955	COG2833	Protein of unknown function (DUF455)
XCCCN07v2_RS04960	COG3291	Pkd domain containing protein
XCCCN07v2_RS04970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCCCN07v2_RS04975	COG0671	phosphoesterase, PA-phosphatase related
XCCCN07v2_RS04980	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS04990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCCCN07v2_RS05000	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS05005	COG4783	chaperone-mediated protein folding
XCCCN07v2_RS05020	COG0473	3-isopropylmalate dehydrogenase activity
XCCCN07v2_RS05120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCCCN07v2_RS05125	COG0631	protein serine/threonine phosphatase activity
XCCCN07v2_RS05140	COG0859	PFAM glycosyl transferase family 9
XCCCN07v2_RS05150	COG1234	tRNA 3'-trailer cleavage
XCCCN07v2_RS05170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCCCN07v2_RS05175	COG0314	molybdopterin synthase activity
XCCCN07v2_RS05205	COG0537	adenosine 5'-monophosphoramidase activity
XCCCN07v2_RS05225	COG0714	Associated with various cellular activities
XCCCN07v2_RS05260	COG1399	metal-binding, possibly nucleic acid-binding protein
XCCCN07v2_RS05270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN07v2_RS05275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCCCN07v2_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS05295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCCCN07v2_RS05300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCCCN07v2_RS05340	COG3829	transcription factor binding
XCCCN07v2_RS05360	COG3609	addiction module antidote protein, CC2985 family
XCCCN07v2_RS05390	COG2373	Large extracellular alpha-helical protein
XCCCN07v2_RS05415	COG4953	penicillin-binding protein 1C
XCCCN07v2_RS05425	COG0678	peroxiredoxin activity
XCCCN07v2_RS05425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XCCCN07v2_RS05445	COG0330	HflC and HflK could
XCCCN07v2_RS05450	COG0330	HflC and HflK could
XCCCN07v2_RS05465	COG0308	aminopeptidase N
XCCCN07v2_RS05490	COG3039	Transposase
XCCCN07v2_RS05510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XCCCN07v2_RS05525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN07v2_RS05560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN07v2_RS05575	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN07v2_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS05590	COG3537	Alpha-1,2-mannosidase
XCCCN07v2_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS05630	COG3039	Transposase
XCCCN07v2_RS05645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN07v2_RS05650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN07v2_RS05655	COG2080	2 iron, 2 sulfur cluster binding
XCCCN07v2_RS05685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN07v2_RS05710	COG1297	OPT oligopeptide transporter protein
XCCCN07v2_RS05720	COG1506	peptidase
XCCCN07v2_RS05720	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN07v2_RS05740	COG2207	Transcriptional regulator
XCCCN07v2_RS05740	COG1917	Cupin 2, conserved barrel domain protein
XCCCN07v2_RS05755	COG0753	catalase activity
XCCCN07v2_RS05760	COG0656	L-ascorbic acid biosynthetic process
XCCCN07v2_RS05780	COG2814	Major facilitator Superfamily
XCCCN07v2_RS05820	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS05825	COG5002	protein histidine kinase activity
XCCCN07v2_RS05840	COG2894	cell division
XCCCN07v2_RS05845	COG0850	regulation of cytokinetic process
XCCCN07v2_RS05860	COG2197	response regulator
XCCCN07v2_RS05885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN07v2_RS05965	COG1946	Acyl-CoA thioesterase
XCCCN07v2_RS05970	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS05975	COG0824	Thioesterase
XCCCN07v2_RS05980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCCCN07v2_RS06010	COG0196	riboflavin kinase activity
XCCCN07v2_RS06040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCCCN07v2_RS06045	COG1845	cytochrome c oxidase, subunit III
XCCCN07v2_RS06050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCCCN07v2_RS06065	COG3152	Membrane
XCCCN07v2_RS06080	COG2207	Transcriptional regulator
XCCCN07v2_RS06085	COG0326	Molecular chaperone. Has ATPase activity
XCCCN07v2_RS06095	COG1902	pentaerythritol trinitrate reductase activity
XCCCN07v2_RS06100	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN07v2_RS06105	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN07v2_RS06110	COG2172	sigma factor antagonist activity
XCCCN07v2_RS06145	COG4771	TonB-dependent receptor
XCCCN07v2_RS06160	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCCCN07v2_RS06165	COG2205	protein histidine kinase activity
XCCCN07v2_RS06175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN07v2_RS06180	COG3437	response regulator, receiver
XCCCN07v2_RS06180	COG2205	protein histidine kinase activity
XCCCN07v2_RS06180	COG3850	Histidine kinase
XCCCN07v2_RS06180	COG4999	Histidine kinase
XCCCN07v2_RS06185	COG4191	Histidine kinase
XCCCN07v2_RS06185	COG0784	Response regulator, receiver
XCCCN07v2_RS06215	COG3534	alpha-L-arabinofuranosidase
XCCCN07v2_RS06225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN07v2_RS06230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCCCN07v2_RS06245	COG2070	2-Nitropropane dioxygenase
XCCCN07v2_RS06275	COG0534	Mate efflux family protein
XCCCN07v2_RS06295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCCCN07v2_RS06305	COG3483	tryptophan 2,3-dioxygenase activity
XCCCN07v2_RS06330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN07v2_RS06340	COG0436	Aminotransferase
XCCCN07v2_RS06345	COG1309	transcriptional regulator
XCCCN07v2_RS06365	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN07v2_RS06420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCCCN07v2_RS06525	COG3039	Transposase
XCCCN07v2_RS06570	COG3250	beta-galactosidase activity
XCCCN07v2_RS06575	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCCCN07v2_RS06585	COG1396	sequence-specific DNA binding
XCCCN07v2_RS06585	COG3800	Transcriptional regulator
XCCCN07v2_RS06595	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS06600	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS06605	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XCCCN07v2_RS06635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN07v2_RS06685	COG2954	triphosphatase activity
XCCCN07v2_RS06690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCCCN07v2_RS06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN07v2_RS06695	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCCCN07v2_RS06700	COG3046	protein related to deoxyribodipyrimidine photolyase
XCCCN07v2_RS06710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCCCN07v2_RS06715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCCCN07v2_RS06720	COG1278	Cold shock
XCCCN07v2_RS06725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN07v2_RS06735	COG1201	RNA secondary structure unwinding
XCCCN07v2_RS06740	COG1793	dna ligase
XCCCN07v2_RS06750	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCCCN07v2_RS06750	COG1793	dna ligase
XCCCN07v2_RS06785	COG0183	Belongs to the thiolase family
XCCCN07v2_RS06805	COG1451	nucleotide metabolic process
XCCCN07v2_RS06810	COG5487	UPF0391 membrane protein
XCCCN07v2_RS06820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCCCN07v2_RS06870	COG1047	Peptidyl-prolyl cis-trans
XCCCN07v2_RS06880	COG2824	Alkylphosphonate utilization operon protein PhnA
XCCCN07v2_RS06900	COG1902	pentaerythritol trinitrate reductase activity
XCCCN07v2_RS06905	COG2814	Major facilitator Superfamily
XCCCN07v2_RS06940	COG0392	lysyltransferase activity
XCCCN07v2_RS06940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCCCN07v2_RS06950	COG0251	oxidation-reduction process
XCCCN07v2_RS06955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN07v2_RS06970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN07v2_RS06995	COG1595	DNA-templated transcription, initiation
XCCCN07v2_RS07010	COG2878	Part of a membrane complex involved in electron transport
XCCCN07v2_RS07035	COG0346	lactoylglutathione lyase activity
XCCCN07v2_RS07040	COG0833	amino acid
XCCCN07v2_RS07045	COG2040	homocysteine
XCCCN07v2_RS07055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN07v2_RS07080	COG1695	Transcriptional regulator
XCCCN07v2_RS07105	COG1981	membrane
XCCCN07v2_RS07160	COG0750	zinc metalloprotease
XCCCN07v2_RS07170	COG0575	Belongs to the CDS family
XCCCN07v2_RS07175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCCCN07v2_RS07185	COG0528	UMP kinase activity
XCCCN07v2_RS07255	COG1393	Belongs to the ArsC family
XCCCN07v2_RS07270	COG0367	asparagine synthase
XCCCN07v2_RS07280	COG4774	siderophore transport
XCCCN07v2_RS07320	COG1566	PFAM secretion protein HlyD family protein
XCCCN07v2_RS07325	COG2814	Major facilitator Superfamily
XCCCN07v2_RS07355	COG3104	oligopeptide transport
XCCCN07v2_RS07390	COG0339	signal peptide processing
XCCCN07v2_RS07395	COG0386	Belongs to the glutathione peroxidase family
XCCCN07v2_RS07455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCCCN07v2_RS07460	COG0084	hydrolase, TatD family'
XCCCN07v2_RS07485	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS07500	COG0367	asparagine synthase
XCCCN07v2_RS07510	COG0305	Participates in initiation and elongation during chromosome replication
XCCCN07v2_RS07515	COG0415	Belongs to the DNA photolyase family
XCCCN07v2_RS07525	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS07535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN07v2_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS07565	COG3706	GGDEF domain
XCCCN07v2_RS07650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN07v2_RS07660	COG0497	DNA recombination
XCCCN07v2_RS07665	COG1420	regulation of RNA biosynthetic process
XCCCN07v2_RS07670	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCCCN07v2_RS07690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCCCN07v2_RS07715	COG2274	protein secretion by the type I secretion system
XCCCN07v2_RS07720	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS07725	COG1132	(ABC) transporter
XCCCN07v2_RS07760	COG2850	peptidyl-arginine hydroxylation
XCCCN07v2_RS07805	COG1131	(ABC) transporter
XCCCN07v2_RS07810	COG1725	Transcriptional regulator
XCCCN07v2_RS07820	COG0386	Belongs to the glutathione peroxidase family
XCCCN07v2_RS07860	COG1609	Transcriptional regulator
XCCCN07v2_RS07870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN07v2_RS07880	COG0646	methionine synthase
XCCCN07v2_RS07880	COG1410	methionine synthase
XCCCN07v2_RS07885	COG0646	methionine synthase
XCCCN07v2_RS07885	COG1410	methionine synthase
XCCCN07v2_RS07890	COG2226	methyltransferase
XCCCN07v2_RS07895	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS07900	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS07905	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS07910	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS07925	COG0557	exoribonuclease II activity
XCCCN07v2_RS07935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN07v2_RS07955	COG0704	Plays a role in the regulation of phosphate uptake
XCCCN07v2_RS07965	COG0581	inorganic phosphate transmembrane transporter activity
XCCCN07v2_RS07970	COG0573	inorganic phosphate transmembrane transporter activity
XCCCN07v2_RS07975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCCCN07v2_RS08000	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN07v2_RS08005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCCCN07v2_RS08015	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS08025	COG0494	nUDIX hydrolase
XCCCN07v2_RS08060	COG2264	protein methyltransferase activity
XCCCN07v2_RS08065	COG0488	(ABC) transporter
XCCCN07v2_RS08090	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCCCN07v2_RS08105	COG2925	Exonuclease
XCCCN07v2_RS08130	COG0288	reversible hydration of carbon dioxide
XCCCN07v2_RS08160	COG0316	Belongs to the HesB IscA family
XCCCN07v2_RS08200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN07v2_RS08210	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCCCN07v2_RS08230	COG4993	Dehydrogenase
XCCCN07v2_RS08240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCCCN07v2_RS08295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCCCN07v2_RS08305	COG0077	Prephenate dehydratase
XCCCN07v2_RS08305	COG1605	Chorismate mutase
XCCCN07v2_RS08315	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCCCN07v2_RS08330	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS08345	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XCCCN07v2_RS08370	COG0497	DNA recombination
XCCCN07v2_RS08460	COG2003	Belongs to the UPF0758 family
XCCCN07v2_RS08475	COG3039	Transposase
XCCCN07v2_RS08550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN07v2_RS08565	COG2801	Transposase and inactivated derivatives
XCCCN07v2_RS08590	COG3039	Transposase
XCCCN07v2_RS08630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCCCN07v2_RS08680	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCCCN07v2_RS08685	COG0784	Response regulator, receiver
XCCCN07v2_RS08685	COG4191	Histidine kinase
XCCCN07v2_RS08700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN07v2_RS08720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN07v2_RS08755	COG3038	cytochrome b561
XCCCN07v2_RS08770	COG2244	polysaccharide biosynthetic process
XCCCN07v2_RS08800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN07v2_RS08805	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS08810	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS08835	COG0477	Major facilitator Superfamily
XCCCN07v2_RS08840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCCCN07v2_RS08855	COG1253	flavin adenine dinucleotide binding
XCCCN07v2_RS08880	COG2134	cdp-diacylglycerol pyrophosphatase
XCCCN07v2_RS08940	COG2840	Smr protein MutS2
XCCCN07v2_RS08955	COG1238	metal cluster binding
XCCCN07v2_RS08970	COG1534	Rna-binding protein
XCCCN07v2_RS08980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCCCN07v2_RS08985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCCCN07v2_RS09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCCCN07v2_RS09005	COG1546	Belongs to the CinA family
XCCCN07v2_RS09015	COG4771	TonB-dependent receptor
XCCCN07v2_RS09025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN07v2_RS09060	COG1741	Belongs to the pirin family
XCCCN07v2_RS09065	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS09090	COG0351	phosphomethylpyrimidine kinase
XCCCN07v2_RS09090	COG0352	thiamine-phosphate diphosphorylase activity
XCCCN07v2_RS09100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCCCN07v2_RS09105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCCCN07v2_RS09120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN07v2_RS09130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCCCN07v2_RS09135	COG3734	2-keto-3-deoxy-galactonokinase
XCCCN07v2_RS09150	COG0800	Aldolase
XCCCN07v2_RS09195	COG1501	Belongs to the glycosyl hydrolase 31 family
XCCCN07v2_RS09205	COG1070	Carbohydrate kinase
XCCCN07v2_RS09215	COG0477	Major facilitator Superfamily
XCCCN07v2_RS09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN07v2_RS09290	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN07v2_RS09300	COG5001	Diguanylate cyclase
XCCCN07v2_RS09300	COG2203	Gaf domain
XCCCN07v2_RS09300	COG3706	GGDEF domain
XCCCN07v2_RS09300	COG4251	negative regulation of phosphorylation
XCCCN07v2_RS09305	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN07v2_RS09310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCCCN07v2_RS09325	COG0671	phosphoesterase, PA-phosphatase related
XCCCN07v2_RS09335	COG1794	racemase activity, acting on amino acids and derivatives
XCCCN07v2_RS09340	COG0697	spore germination
XCCCN07v2_RS09365	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN07v2_RS09415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCCCN07v2_RS09425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN07v2_RS09455	COG0131	Imidazoleglycerol-phosphate dehydratase
XCCCN07v2_RS09455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCCCN07v2_RS09475	COG0140	phosphoribosyl-ATP diphosphatase activity
XCCCN07v2_RS09475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCCCN07v2_RS09505	COG0531	amino acid
XCCCN07v2_RS09510	COG0531	amino acid
XCCCN07v2_RS09525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN07v2_RS09530	COG0277	FAD linked oxidase domain protein
XCCCN07v2_RS09565	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS09590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN07v2_RS09595	COG2258	MOSC domain
XCCCN07v2_RS09605	COG0505	Belongs to the CarA family
XCCCN07v2_RS09615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCCCN07v2_RS09620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN07v2_RS09630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCCCN07v2_RS09655	COG3279	Response regulator of the LytR AlgR family
XCCCN07v2_RS09675	COG2198	Histidine kinase
XCCCN07v2_RS09675	COG2205	protein histidine kinase activity
XCCCN07v2_RS09675	COG0784	Response regulator, receiver
XCCCN07v2_RS09680	COG0784	Response regulator, receiver
XCCCN07v2_RS09680	COG2205	protein histidine kinase activity
XCCCN07v2_RS09680	COG2198	Histidine kinase
XCCCN07v2_RS09685	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS09690	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN07v2_RS09720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN07v2_RS09745	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09755	COG0835	chemotaxis
XCCCN07v2_RS09775	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09780	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09785	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09790	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09795	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09800	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09815	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS09825	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS09835	COG0835	chemotaxis
XCCCN07v2_RS09840	COG1192	Involved in chromosome partitioning
XCCCN07v2_RS09845	COG1360	Flagellar Motor Protein
XCCCN07v2_RS09850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCCCN07v2_RS09920	COG3039	Transposase
XCCCN07v2_RS09950	COG0643	Histidine kinase
XCCCN07v2_RS09950	COG2198	Histidine kinase
XCCCN07v2_RS09950	COG0784	Response regulator, receiver
XCCCN07v2_RS10005	COG1684	flagellar biosynthetic protein fliR
XCCCN07v2_RS10010	COG1987	bacterial-type flagellum assembly
XCCCN07v2_RS10075	COG1677	Flagellar hook-basal body complex protein FliE
XCCCN07v2_RS10080	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS10080	COG1216	Glycosyl transferase, family 2
XCCCN07v2_RS10110	COG2201	protein-glutamate methylesterase activity
XCCCN07v2_RS10140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCCCN07v2_RS10145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN07v2_RS10150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN07v2_RS10160	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCCCN07v2_RS10160	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCCCN07v2_RS10180	COG4787	bacterial-type flagellum-dependent cell motility
XCCCN07v2_RS10190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCCCN07v2_RS10195	COG1558	bacterial-type flagellum-dependent cell motility
XCCCN07v2_RS10205	COG0784	Response regulator, receiver
XCCCN07v2_RS10205	COG0835	chemotaxis
XCCCN07v2_RS10225	COG4191	Histidine kinase
XCCCN07v2_RS10260	COG2915	High frequency lysogenization protein hflD homolog
XCCCN07v2_RS10280	COG0542	response to heat
XCCCN07v2_RS10300	COG0492	ferredoxin-NADP+ reductase activity
XCCCN07v2_RS10305	COG1674	ftsk spoiiie
XCCCN07v2_RS10325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCCCN07v2_RS10330	COG0038	chloride channel
XCCCN07v2_RS10335	COG0183	Belongs to the thiolase family
XCCCN07v2_RS10340	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCCCN07v2_RS10340	COG1024	Enoyl-CoA hydratase
XCCCN07v2_RS10375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN07v2_RS10390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCCCN07v2_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS10410	COG2124	cytochrome p450
XCCCN07v2_RS10440	COG0708	Exodeoxyribonuclease III
XCCCN07v2_RS10445	COG3039	Transposase
XCCCN07v2_RS10455	COG0303	'Molybdopterin
XCCCN07v2_RS10460	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN07v2_RS10470	COG1648	precorrin-2 dehydrogenase activity
XCCCN07v2_RS10470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCCCN07v2_RS10480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCCCN07v2_RS10485	COG2223	nitrite transmembrane transporter activity
XCCCN07v2_RS10490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCCCN07v2_RS10500	COG0243	molybdopterin cofactor binding
XCCCN07v2_RS10530	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCCCN07v2_RS10540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN07v2_RS10550	COG0579	oxidoreductase
XCCCN07v2_RS10565	COG3685	Protein conserved in bacteria
XCCCN07v2_RS10570	COG2201	protein-glutamate methylesterase activity
XCCCN07v2_RS10580	COG5001	Diguanylate cyclase
XCCCN07v2_RS10645	COG3590	peptidase
XCCCN07v2_RS10660	COG1999	signal sequence binding
XCCCN07v2_RS10675	COG1733	regulation of RNA biosynthetic process
XCCCN07v2_RS10705	COG1238	metal cluster binding
XCCCN07v2_RS10715	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS10730	COG3039	Transposase
XCCCN07v2_RS10750	COG0784	Response regulator, receiver
XCCCN07v2_RS10750	COG4191	Histidine kinase
XCCCN07v2_RS10760	COG3459	Glycosyltransferase 36 associated
XCCCN07v2_RS10830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN07v2_RS11085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN07v2_RS11175	COG0428	transporter
XCCCN07v2_RS11185	COG1530	ribonuclease E activity
XCCCN07v2_RS11220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCCCN07v2_RS11320	COG0582	viral genome integration into host DNA
XCCCN07v2_RS11340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN07v2_RS11355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCCCN07v2_RS11375	COG0848	biopolymer transport protein
XCCCN07v2_RS11380	COG0811	peptide transport
XCCCN07v2_RS11400	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCCCN07v2_RS11415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCCCN07v2_RS11425	COG1053	succinate dehydrogenase
XCCCN07v2_RS11430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCCCN07v2_RS11445	COG0354	folic acid binding
XCCCN07v2_RS11465	COG0363	glucosamine-6-phosphate deaminase activity
XCCCN07v2_RS11470	COG0129	dihydroxy-acid dehydratase activity
XCCCN07v2_RS11475	COG0800	Aldolase
XCCCN07v2_RS11540	COG5001	Diguanylate cyclase
XCCCN07v2_RS11545	COG2183	response to ionizing radiation
XCCCN07v2_RS11555	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN07v2_RS11555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN07v2_RS11570	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCCCN07v2_RS11580	COG1183	phosphatidylcholine synthase activity
XCCCN07v2_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS11610	COG0668	transmembrane transport
XCCCN07v2_RS11630	COG1914	H( )-stimulated, divalent metal cation uptake system
XCCCN07v2_RS11645	COG2814	Major facilitator Superfamily
XCCCN07v2_RS11660	COG1335	isochorismatase
XCCCN07v2_RS11675	COG2197	response regulator
XCCCN07v2_RS11715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN07v2_RS11715	COG0475	glutathione-regulated potassium exporter activity
XCCCN07v2_RS11720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCCCN07v2_RS11735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCCCN07v2_RS11750	COG0539	negative regulation of cytoplasmic translation
XCCCN07v2_RS11770	COG2957	Belongs to the agmatine deiminase family
XCCCN07v2_RS11775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN07v2_RS11800	COG0395	ABC-type sugar transport system, permease component
XCCCN07v2_RS11810	COG2182	Extracellular solute-binding protein
XCCCN07v2_RS11835	COG2350	Protein conserved in bacteria
XCCCN07v2_RS11840	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCCCN07v2_RS11845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCCCN07v2_RS11850	COG1187	pseudouridine synthase activity
XCCCN07v2_RS11875	COG0436	Aminotransferase
XCCCN07v2_RS11940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCCCN07v2_RS11945	COG4988	ABC transporter
XCCCN07v2_RS11955	COG1294	oxidase, subunit
XCCCN07v2_RS12015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCCCN07v2_RS12020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN07v2_RS12025	COG0137	argininosuccinate synthase activity
XCCCN07v2_RS12035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCCCN07v2_RS12050	COG2166	iron-sulfur cluster assembly
XCCCN07v2_RS12080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCCCN07v2_RS12100	COG4302	ethanolamine ammonia-lyase activity
XCCCN07v2_RS12150	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN07v2_RS12165	COG1509	lysine 2,3-aminomutase activity
XCCCN07v2_RS12170	COG3300	MHYT domain
XCCCN07v2_RS12170	COG5001	Diguanylate cyclase
XCCCN07v2_RS12185	COG0483	inositol monophosphate 1-phosphatase activity
XCCCN07v2_RS12190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN07v2_RS12205	COG0488	(ABC) transporter
XCCCN07v2_RS12210	COG0513	Belongs to the DEAD box helicase family
XCCCN07v2_RS12245	COG4681	YaeQ
XCCCN07v2_RS12250	COG2081	HI0933 family
XCCCN07v2_RS12255	COG5001	Diguanylate cyclase
XCCCN07v2_RS12255	COG3300	MHYT domain
XCCCN07v2_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS12295	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN07v2_RS12305	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCCCN07v2_RS12305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN07v2_RS12310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCCCN07v2_RS12325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN07v2_RS12370	COG0835	chemotaxis
XCCCN07v2_RS12375	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS12385	COG1201	RNA secondary structure unwinding
XCCCN07v2_RS12400	COG2969	positive regulation of protein catabolic process
XCCCN07v2_RS12405	COG0625	glutathione transferase activity
XCCCN07v2_RS12410	COG2857	Cytochrome c1
XCCCN07v2_RS12415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCCCN07v2_RS12420	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN07v2_RS12425	COG0741	lytic transglycosylase activity
XCCCN07v2_RS12445	COG1702	phosphate starvation-inducible protein PhoH
XCCCN07v2_RS12465	COG4535	Mg2 and Co2 transporter CorC
XCCCN07v2_RS12480	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN07v2_RS12490	COG1177	transmembrane transport
XCCCN07v2_RS12495	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCCCN07v2_RS12505	COG3842	ATPase activity
XCCCN07v2_RS12540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCCCN07v2_RS12545	COG0174	glutamine synthetase
XCCCN07v2_RS12550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN07v2_RS12560	COG2703	oxygen carrier activity
XCCCN07v2_RS12575	COG0243	molybdopterin cofactor binding
XCCCN07v2_RS12585	COG2223	nitrite transmembrane transporter activity
XCCCN07v2_RS12595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCCCN07v2_RS12605	COG2733	membrane
XCCCN07v2_RS12610	COG5002	protein histidine kinase activity
XCCCN07v2_RS12610	COG2205	protein histidine kinase activity
XCCCN07v2_RS12610	COG0784	Response regulator, receiver
XCCCN07v2_RS12620	COG0477	Major facilitator Superfamily
XCCCN07v2_RS12625	COG1335	isochorismatase
XCCCN07v2_RS12630	COG1609	Transcriptional regulator
XCCCN07v2_RS12630	COG2207	Transcriptional regulator
XCCCN07v2_RS12635	COG2902	Dehydrogenase
XCCCN07v2_RS12645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN07v2_RS12650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN07v2_RS12660	COG1609	Transcriptional regulator
XCCCN07v2_RS12665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN07v2_RS12665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN07v2_RS12670	COG1105	Belongs to the carbohydrate kinase PfkB family
XCCCN07v2_RS12675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN07v2_RS12675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN07v2_RS12695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCCCN07v2_RS12705	COG1862	Preprotein translocase
XCCCN07v2_RS12725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCCCN07v2_RS12755	COG3291	Pkd domain containing protein
XCCCN07v2_RS12760	COG0405	Gamma-glutamyltransferase
XCCCN07v2_RS12765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCCCN07v2_RS12785	COG0742	ribosomal rna small subunit methyltransferase
XCCCN07v2_RS12790	COG0326	Molecular chaperone. Has ATPase activity
XCCCN07v2_RS12805	COG4206	TonB-dependent receptor
XCCCN07v2_RS12815	COG1506	peptidase
XCCCN07v2_RS12815	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN07v2_RS12820	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN07v2_RS12830	COG4206	TonB-dependent receptor
XCCCN07v2_RS12860	COG0531	amino acid
XCCCN07v2_RS12880	COG0006	proline dipeptidase activity
XCCCN07v2_RS12890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN07v2_RS12910	COG3938	Belongs to the proline racemase family
XCCCN07v2_RS12920	COG0552	protein localization to endoplasmic reticulum
XCCCN07v2_RS12940	COG4191	Histidine kinase
XCCCN07v2_RS12940	COG0784	Response regulator, receiver
XCCCN07v2_RS12950	COG3039	Transposase
XCCCN07v2_RS12955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN07v2_RS12975	COG0322	excinuclease ABC activity
XCCCN07v2_RS13000	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS13030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN07v2_RS13040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN07v2_RS13070	COG2244	polysaccharide biosynthetic process
XCCCN07v2_RS13075	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS13080	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS13150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCCCN07v2_RS13180	COG1082	Xylose isomerase domain protein TIM barrel
XCCCN07v2_RS13190	COG3039	Transposase
XCCCN07v2_RS13200	COG0366	Alpha amylase catalytic
XCCCN07v2_RS13210	COG2801	Transposase and inactivated derivatives
XCCCN07v2_RS13225	COG3702	type iv secretory pathway
XCCCN07v2_RS13245	COG2948	multi-organism process
XCCCN07v2_RS13265	COG3505	Type IV secretory pathway VirD4
XCCCN07v2_RS13290	COG4969	Belongs to the N-Me-Phe pilin family
XCCCN07v2_RS13325	COG4969	Belongs to the N-Me-Phe pilin family
XCCCN07v2_RS13330	COG1611	Belongs to the LOG family
XCCCN07v2_RS13340	COG2095	MarC family integral membrane protein
XCCCN07v2_RS13350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN07v2_RS13410	COG0195	Participates in both transcription termination and antitermination
XCCCN07v2_RS13425	COG1007	ATP synthesis coupled electron transport
XCCCN07v2_RS13445	COG0839	Belongs to the complex I subunit 6 family
XCCCN07v2_RS13465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCCCN07v2_RS13470	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCCCN07v2_RS13490	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCCCN07v2_RS13510	COG4221	oxidoreductase activity
XCCCN07v2_RS13595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCCCN07v2_RS13600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCCCN07v2_RS13615	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN07v2_RS13640	COG0433	COG0433 Predicted ATPase
XCCCN07v2_RS13655	COG0494	nUDIX hydrolase
XCCCN07v2_RS13670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN07v2_RS13680	COG3039	Transposase
XCCCN07v2_RS13690	COG0412	Dienelactone hydrolase
XCCCN07v2_RS13715	COG0489	protein tyrosine kinase activity
XCCCN07v2_RS13735	COG3590	peptidase
XCCCN07v2_RS13740	COG3590	peptidase
XCCCN07v2_RS13760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN07v2_RS13765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN07v2_RS13770	COG2311	Membrane
XCCCN07v2_RS13775	COG1047	Peptidyl-prolyl cis-trans
XCCCN07v2_RS13780	COG0791	NLP P60 protein
XCCCN07v2_RS13785	COG0791	NLP P60 protein
XCCCN07v2_RS13815	COG3852	Histidine kinase
XCCCN07v2_RS13830	COG4106	trans-aconitate 2-methyltransferase activity
XCCCN07v2_RS13835	COG1301	dicarboxylic acid transport
XCCCN07v2_RS13855	COG0142	geranyltranstransferase activity
XCCCN07v2_RS13875	COG0312	modulator of DNA gyrase
XCCCN07v2_RS13885	COG0312	modulator of DNA gyrase
XCCCN07v2_RS13895	COG3164	Protein of unknown function
XCCCN07v2_RS13910	COG2968	Membrane
XCCCN07v2_RS13935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCCCN07v2_RS13960	COG3118	belongs to the thioredoxin family
XCCCN07v2_RS13970	COG2155	Conserved Protein
XCCCN07v2_RS14025	COG1132	(ABC) transporter
XCCCN07v2_RS14030	COG0475	glutathione-regulated potassium exporter activity
XCCCN07v2_RS14055	COG1187	pseudouridine synthase activity
XCCCN07v2_RS14060	COG5001	Diguanylate cyclase
XCCCN07v2_RS14060	COG5002	protein histidine kinase activity
XCCCN07v2_RS14160	COG1294	oxidase, subunit
XCCCN07v2_RS14165	COG1271	oxidase subunit
XCCCN07v2_RS14175	COG3383	formate dehydrogenase (NAD+) activity
XCCCN07v2_RS14205	COG2814	Major facilitator Superfamily
XCCCN07v2_RS14210	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS14240	COG2207	Transcriptional regulator
XCCCN07v2_RS14255	COG0667	Aldo Keto reductase
XCCCN07v2_RS14260	COG1309	transcriptional regulator
XCCCN07v2_RS14270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN07v2_RS14285	COG0735	belongs to the Fur family
XCCCN07v2_RS14320	COG4452	Inner membrane protein CreD
XCCCN07v2_RS14330	COG2205	protein histidine kinase activity
XCCCN07v2_RS14335	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS14340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCCCN07v2_RS14355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCCCN07v2_RS14365	COG0643	Histidine kinase
XCCCN07v2_RS14365	COG2198	Histidine kinase
XCCCN07v2_RS14370	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS14375	COG0835	chemotaxis
XCCCN07v2_RS14380	COG2199	diguanylate cyclase activity
XCCCN07v2_RS14380	COG2200	EAL domain
XCCCN07v2_RS14380	COG2202	Pas domain
XCCCN07v2_RS14385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN07v2_RS14395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS14405	COG3039	Transposase
XCCCN07v2_RS14410	COG3590	peptidase
XCCCN07v2_RS14430	COG1741	Belongs to the pirin family
XCCCN07v2_RS14450	COG1741	Belongs to the pirin family
XCCCN07v2_RS14455	COG1966	Carbon starvation protein
XCCCN07v2_RS14460	COG2879	small protein
XCCCN07v2_RS14490	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN07v2_RS14495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCCCN07v2_RS14500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN07v2_RS14505	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN07v2_RS14510	COG2080	2 iron, 2 sulfur cluster binding
XCCCN07v2_RS14515	COG0604	alcohol dehydrogenase
XCCCN07v2_RS14535	COG0629	single-stranded DNA binding
XCCCN07v2_RS14540	COG0142	geranyltranstransferase activity
XCCCN07v2_RS14565	COG0527	aspartate kinase activity
XCCCN07v2_RS14570	COG0384	phenazine biosynthesis protein PhzF
XCCCN07v2_RS14575	COG0384	phenazine biosynthesis protein PhzF
XCCCN07v2_RS14585	COG1764	response to oxidative stress
XCCCN07v2_RS14605	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCCCN07v2_RS14610	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN07v2_RS14640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCCCN07v2_RS14675	COG0693	protein deglycase activity
XCCCN07v2_RS14690	COG0719	Fe-S assembly protein
XCCCN07v2_RS14695	COG0396	ATPase activity
XCCCN07v2_RS14700	COG0719	Fe-S assembly protein
XCCCN07v2_RS14705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN07v2_RS14720	COG4774	siderophore transport
XCCCN07v2_RS14765	COG1555	photosystem II stabilization
XCCCN07v2_RS14770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN07v2_RS14785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN07v2_RS14795	COG0628	permease
XCCCN07v2_RS14815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCCCN07v2_RS14840	COG0271	Belongs to the BolA IbaG family
XCCCN07v2_RS14850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCCCN07v2_RS14865	COG1137	ATPase activity
XCCCN07v2_RS14880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN07v2_RS14900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN07v2_RS14905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN07v2_RS14910	COG2239	Acts as a magnesium transporter
XCCCN07v2_RS14920	COG1294	oxidase, subunit
XCCCN07v2_RS14930	COG1113	amino acid transport
XCCCN07v2_RS14950	COG2197	response regulator
XCCCN07v2_RS14955	COG0531	amino acid
XCCCN07v2_RS15020	COG0754	glutathionylspermidine amidase activity
XCCCN07v2_RS15045	COG1842	Phage shock protein A
XCCCN07v2_RS15080	COG0477	Major facilitator Superfamily
XCCCN07v2_RS15100	COG2353	YceI-like domain
XCCCN07v2_RS15120	COG1760	l-serine dehydratase
XCCCN07v2_RS15135	COG0527	aspartate kinase activity
XCCCN07v2_RS15135	COG0460	homoserine dehydrogenase
XCCCN07v2_RS15140	COG0626	cystathionine gamma-synthase activity
XCCCN07v2_RS15145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN07v2_RS15160	COG1272	protein, Hemolysin III
XCCCN07v2_RS15165	COG2982	Protein involved in outer membrane biogenesis
XCCCN07v2_RS15170	COG0516	GMP reductase activity
XCCCN07v2_RS15170	COG0517	IMP dehydrogenase activity
XCCCN07v2_RS15175	COG0463	Glycosyl transferase, family 2
XCCCN07v2_RS15185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCCCN07v2_RS15200	COG1309	transcriptional regulator
XCCCN07v2_RS15210	COG1960	acyl-CoA dehydrogenase activity
XCCCN07v2_RS15260	COG0330	HflC and HflK could
XCCCN07v2_RS15270	COG3956	TIGRFAM MazG family protein
XCCCN07v2_RS15275	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCCCN07v2_RS15280	COG0494	nUDIX hydrolase
XCCCN07v2_RS15290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCCCN07v2_RS15315	COG3858	chitin binding
XCCCN07v2_RS15315	COG1388	LysM domain
XCCCN07v2_RS15320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCCCN07v2_RS15330	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN07v2_RS15340	COG3537	Alpha-1,2-mannosidase
XCCCN07v2_RS15400	COG3645	SOS response
XCCCN07v2_RS15415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN07v2_RS15465	COG1446	asparaginase
XCCCN07v2_RS15470	COG2304	oxidoreductase activity
XCCCN07v2_RS15475	COG1595	DNA-templated transcription, initiation
XCCCN07v2_RS15510	COG2198	Histidine kinase
XCCCN07v2_RS15510	COG0784	Response regulator, receiver
XCCCN07v2_RS15510	COG0643	Histidine kinase
XCCCN07v2_RS15515	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS15520	COG0835	chemotaxis
XCCCN07v2_RS15535	COG0189	ligase activity
XCCCN07v2_RS15545	COG1397	ADP-ribosylglycohydrolase
XCCCN07v2_RS15560	COG1199	ATP-dependent helicase activity
XCCCN07v2_RS15570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCCCN07v2_RS15575	COG1215	transferase activity, transferring glycosyl groups
XCCCN07v2_RS15585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN07v2_RS15635	COG1643	Atp-dependent helicase
XCCCN07v2_RS15640	COG0783	Belongs to the Dps family
XCCCN07v2_RS15645	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN07v2_RS15660	COG1187	pseudouridine synthase activity
XCCCN07v2_RS15685	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS15730	COG0602	queuosine metabolic process
XCCCN07v2_RS15740	COG2885	chlorophyll binding
XCCCN07v2_RS15755	COG0848	biopolymer transport protein
XCCCN07v2_RS15765	COG0824	Thioesterase
XCCCN07v2_RS15835	COG0477	Major facilitator Superfamily
XCCCN07v2_RS15855	COG2755	lipolytic protein G-D-S-L family
XCCCN07v2_RS15855	COG0657	acetylesterase activity
XCCCN07v2_RS15880	COG0488	(ABC) transporter
XCCCN07v2_RS15910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN07v2_RS15910	COG4651	solute:proton antiporter activity
XCCCN07v2_RS15920	COG4772	TonB-dependent receptor
XCCCN07v2_RS15930	COG4264	IucA IucC family
XCCCN07v2_RS15935	COG2814	Major facilitator Superfamily
XCCCN07v2_RS15940	COG4264	IucA IucC family
XCCCN07v2_RS15945	COG0019	diaminopimelate decarboxylase activity
XCCCN07v2_RS15955	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCCCN07v2_RS15985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN07v2_RS15990	COG1797	cobyrinic acid a,c-diamide synthase activity
XCCCN07v2_RS16010	COG4206	TonB-dependent receptor
XCCCN07v2_RS16025	COG0542	response to heat
XCCCN07v2_RS16030	COG1116	anion transmembrane transporter activity
XCCCN07v2_RS16075	COG1877	trehalose-phosphatase activity
XCCCN07v2_RS16080	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN07v2_RS16095	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS16110	COG1496	oxidoreductase activity
XCCCN07v2_RS16115	COG0564	pseudouridine synthase activity
XCCCN07v2_RS16120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN07v2_RS16130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCCCN07v2_RS16130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN07v2_RS16185	COG1459	type II secretion system
XCCCN07v2_RS16190	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCCCN07v2_RS16220	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS16300	COG5001	Diguanylate cyclase
XCCCN07v2_RS16415	COG3039	Transposase
XCCCN07v2_RS16440	COG1396	sequence-specific DNA binding
XCCCN07v2_RS16460	COG0582	viral genome integration into host DNA
XCCCN07v2_RS16490	COG0471	metal ion transport
XCCCN07v2_RS16490	COG3273	potassium ion transport
XCCCN07v2_RS16520	COG1609	Transcriptional regulator
XCCCN07v2_RS16535	COG3250	beta-galactosidase activity
XCCCN07v2_RS16540	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN07v2_RS16545	COG2272	Belongs to the type-B carboxylesterase lipase family
XCCCN07v2_RS16550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN07v2_RS16555	COG1115	amino acid carrier protein
XCCCN07v2_RS16565	COG0308	aminopeptidase N
XCCCN07v2_RS16570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN07v2_RS16575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN07v2_RS16580	COG2895	sulfate adenylyltransferase (ATP) activity
XCCCN07v2_RS16580	COG0529	Catalyzes the synthesis of activated sulfate
XCCCN07v2_RS16590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN07v2_RS16620	COG0784	Response regulator, receiver
XCCCN07v2_RS16620	COG2198	Histidine kinase
XCCCN07v2_RS16620	COG2205	protein histidine kinase activity
XCCCN07v2_RS16655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCCCN07v2_RS16660	COG3588	fructose-bisphosphate aldolase
XCCCN07v2_RS16665	COG0469	pyruvate kinase activity
XCCCN07v2_RS16695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCCCN07v2_RS16710	COG3047	cAMP biosynthetic process
XCCCN07v2_RS16725	COG3453	Protein conserved in bacteria
XCCCN07v2_RS16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN07v2_RS16745	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCCCN07v2_RS16750	COG4149	molybdate abc transporter
XCCCN07v2_RS16795	COG1376	ErfK ybiS ycfS ynhG family protein
XCCCN07v2_RS16800	COG0739	heme binding
XCCCN07v2_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS16810	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS16825	COG0596	Alpha beta hydrolase
XCCCN07v2_RS16830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCCCN07v2_RS16835	COG1301	dicarboxylic acid transport
XCCCN07v2_RS16845	COG2304	oxidoreductase activity
XCCCN07v2_RS16865	COG0714	Associated with various cellular activities
XCCCN07v2_RS16895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCCCN07v2_RS16925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCCCN07v2_RS16935	COG2721	sulfolactate sulfo-lyase activity
XCCCN07v2_RS16950	COG2271	Major facilitator Superfamily
XCCCN07v2_RS16965	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS16975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN07v2_RS16990	COG1561	YicC-like family, N-terminal region
XCCCN07v2_RS17000	COG0346	lactoylglutathione lyase activity
XCCCN07v2_RS17010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCCCN07v2_RS17040	COG0006	proline dipeptidase activity
XCCCN07v2_RS17065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCCCN07v2_RS17085	COG2912	Transglutaminase-like superfamily
XCCCN07v2_RS17090	COG1773	rubredoxin
XCCCN07v2_RS17120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN07v2_RS17150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCCCN07v2_RS17155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN07v2_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS17175	COG0671	phosphoesterase, PA-phosphatase related
XCCCN07v2_RS17180	COG3781	membrane
XCCCN07v2_RS17190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCCCN07v2_RS17240	COG3039	Transposase
XCCCN07v2_RS17285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCCCN07v2_RS17300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCCCN07v2_RS17320	COG3710	Transcriptional regulator
XCCCN07v2_RS17330	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN07v2_RS17330	COG1506	peptidase
XCCCN07v2_RS17330	COG4946	Tricorn protease homolog
XCCCN07v2_RS17335	COG0840	transmembrane signaling receptor activity
XCCCN07v2_RS17340	COG0405	Gamma-glutamyltransferase
XCCCN07v2_RS17375	COG2226	methyltransferase
XCCCN07v2_RS17385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCCCN07v2_RS17395	COG5001	Diguanylate cyclase
XCCCN07v2_RS17395	COG3300	MHYT domain
XCCCN07v2_RS17405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCCCN07v2_RS17410	COG1538	Outer membrane efflux protein
XCCCN07v2_RS17415	COG1519	Transferase
XCCCN07v2_RS17420	COG1560	Kdo2-lipid A biosynthetic process
XCCCN07v2_RS17470	COG4191	Histidine kinase
XCCCN07v2_RS17480	COG2197	response regulator
XCCCN07v2_RS17490	COG0642	Histidine kinase
XCCCN07v2_RS17505	COG2851	Citrate transporter
XCCCN07v2_RS17510	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS17515	COG1609	Transcriptional regulator
XCCCN07v2_RS17520	COG2211	Major facilitator Superfamily
XCCCN07v2_RS17555	COG0436	Aminotransferase
XCCCN07v2_RS17595	COG0604	alcohol dehydrogenase
XCCCN07v2_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS17595	COG3321	synthase
XCCCN07v2_RS17610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN07v2_RS17625	COG0494	nUDIX hydrolase
XCCCN07v2_RS17640	COG0739	heme binding
XCCCN07v2_RS17665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCCCN07v2_RS17670	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN07v2_RS17695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCCCN07v2_RS17710	COG3116	cell division
XCCCN07v2_RS17760	COG1988	membrane-bound metal-dependent
XCCCN07v2_RS17765	COG0277	FAD linked oxidase domain protein
XCCCN07v2_RS17775	COG0745	RESPONSE REGULATOR receiver
XCCCN07v2_RS17780	COG2205	protein histidine kinase activity
XCCCN07v2_RS17790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCCCN07v2_RS17795	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCCCN07v2_RS17810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCCCN07v2_RS17840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN07v2_RS17840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN07v2_RS17865	COG0488	(ABC) transporter
XCCCN07v2_RS17870	COG0242	peptide deformylase activity
XCCCN07v2_RS17875	COG1393	Belongs to the ArsC family
XCCCN07v2_RS17895	COG0457	Tetratricopeptide repeat
XCCCN07v2_RS17950	COG2188	Transcriptional regulator
XCCCN07v2_RS17960	COG1450	Type ii and iii secretion system protein
XCCCN07v2_RS17975	COG3166	PFAM Fimbrial assembly family protein
XCCCN07v2_RS17980	COG3156	type II secretion system protein K
XCCCN07v2_RS17985	COG4795	General secretion pathway protein
XCCCN07v2_RS17990	COG2165	general secretion pathway protein
XCCCN07v2_RS17995	COG4970	Tfp pilus assembly protein FimT
XCCCN07v2_RS18000	COG2165	general secretion pathway protein
XCCCN07v2_RS18005	COG1459	type II secretion system
XCCCN07v2_RS18010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN07v2_RS18015	COG1404	Belongs to the peptidase S8 family
XCCCN07v2_RS18030	COG0047	phosphoribosylformylglycinamidine synthase activity
XCCCN07v2_RS18030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCCCN07v2_RS18035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN07v2_RS18040	COG4974	Belongs to the 'phage' integrase family
XCCCN07v2_RS18055	COG0795	lipopolysaccharide-transporting ATPase activity
XCCCN07v2_RS18115	COG1183	phosphatidylcholine synthase activity
XCCCN07v2_RS18140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN07v2_RS18145	COG1127	ABC transporter
XCCCN07v2_RS18150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN07v2_RS18150	COG3218	ABC-type transport auxiliary lipoprotein component
XCCCN07v2_RS18175	COG3754	Rhamnan synthesis protein F
XCCCN07v2_RS18180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN07v2_RS18185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN07v2_RS18190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCCCN07v2_RS18195	COG0662	Cupin 2, conserved barrel domain protein
XCCCN07v2_RS18195	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN07v2_RS18220	COG2086	electron transfer activity
XCCCN07v2_RS18230	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN07v2_RS18230	COG0662	Cupin 2, conserved barrel domain protein
XCCCN07v2_RS18240	COG0463	Glycosyl transferase, family 2
XCCCN07v2_RS18265	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCCCN07v2_RS18280	COG0438	transferase activity, transferring glycosyl groups
XCCCN07v2_RS18305	COG0626	cystathionine gamma-synthase activity
XCCCN07v2_RS18335	COG0625	glutathione transferase activity
XCCCN07v2_RS18345	COG0513	Belongs to the DEAD box helicase family
XCCCN07v2_RS18350	COG0720	synthase
XCCCN07v2_RS18360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XCCCN07v2_RS18365	COG1956	GAF domain-containing protein
XCCCN07v2_RS18395	COG0339	signal peptide processing
XCCCN07v2_RS18400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCCCN07v2_RS18460	COG1136	(ABC) transporter
XCCCN07v2_RS18470	COG1136	(ABC) transporter
XCCCN07v2_RS18470	COG0577	efflux transmembrane transporter activity
XCCCN07v2_RS18560	COG0356	it plays a direct role in the translocation of protons across the membrane
XCCCN07v2_RS18575	COG1228	amidohydrolase
XCCCN07v2_RS18580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN07v2_RS18590	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN07v2_RS18635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCCCN07v2_RS18655	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS18675	COG2205	protein histidine kinase activity
XCCCN07v2_RS18700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN07v2_RS18710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCCCN07v2_RS18750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCCCN07v2_RS18755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN07v2_RS18760	COG1609	Transcriptional regulator
XCCCN07v2_RS18770	COG2188	Transcriptional regulator
XCCCN07v2_RS18795	COG4795	General secretion pathway protein
XCCCN07v2_RS18800	COG2165	general secretion pathway protein
XCCCN07v2_RS18815	COG1459	type II secretion system
XCCCN07v2_RS18860	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS18865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCCCN07v2_RS18870	COG4191	Histidine kinase
XCCCN07v2_RS18875	COG0784	Response regulator, receiver
XCCCN07v2_RS18880	COG4251	negative regulation of phosphorylation
XCCCN07v2_RS18885	COG2823	Periplasmic or secreted lipoprotein
XCCCN07v2_RS18890	COG0673	inositol 2-dehydrogenase activity
XCCCN07v2_RS18895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCCCN07v2_RS18930	COG1056	cytidyltransferase-related domain
XCCCN07v2_RS18930	COG1051	belongs to the nudix hydrolase family
XCCCN07v2_RS18980	COG1686	Belongs to the peptidase S11 family
XCCCN07v2_RS18985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCCCN07v2_RS18990	COG2951	lytic endotransglycosylase activity
XCCCN07v2_RS19025	COG2011	ABC-type metal ion transport system permease component
XCCCN07v2_RS19035	COG0697	spore germination
XCCCN07v2_RS19065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN07v2_RS19070	COG1187	pseudouridine synthase activity
XCCCN07v2_RS19075	COG2813	Specifically methylates the guanine in position
XCCCN07v2_RS19095	COG5002	protein histidine kinase activity
XCCCN07v2_RS19175	COG0842	Transport permease protein
XCCCN07v2_RS19180	COG1131	(ABC) transporter
XCCCN07v2_RS19185	COG0025	NhaP-type Na H and K H
XCCCN07v2_RS19190	COG3795	YCII-related domain
XCCCN07v2_RS19195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCCCN07v2_RS19200	COG1573	uracil-dna glycosylase
XCCCN07v2_RS19210	COG3384	dioxygenase
XCCCN07v2_RS19215	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS19225	COG0667	Aldo Keto reductase
XCCCN07v2_RS19235	COG3590	peptidase
XCCCN07v2_RS19250	COG0531	amino acid
XCCCN07v2_RS19265	COG2972	Histidine kinase
XCCCN07v2_RS19285	COG1335	isochorismatase
XCCCN07v2_RS19290	COG3685	Protein conserved in bacteria
XCCCN07v2_RS19295	COG3685	Protein conserved in bacteria
XCCCN07v2_RS19300	COG3546	catalase activity
XCCCN07v2_RS19330	COG2204	response regulator
XCCCN07v2_RS19340	COG1271	oxidase subunit
XCCCN07v2_RS19345	COG1294	oxidase, subunit
XCCCN07v2_RS19360	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS19365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCCCN07v2_RS19385	COG1132	(ABC) transporter
XCCCN07v2_RS19400	COG1063	alcohol dehydrogenase
XCCCN07v2_RS19440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN07v2_RS19500	COG0251	oxidation-reduction process
XCCCN07v2_RS19520	COG0667	Aldo Keto reductase
XCCCN07v2_RS19525	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS19545	COG2203	Gaf domain
XCCCN07v2_RS19545	COG3706	GGDEF domain
XCCCN07v2_RS19545	COG4251	negative regulation of phosphorylation
XCCCN07v2_RS19545	COG5001	Diguanylate cyclase
XCCCN07v2_RS19575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN07v2_RS19580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XCCCN07v2_RS19595	COG4695	Portal protein
XCCCN07v2_RS19640	COG3179	chitinase
XCCCN07v2_RS19835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN07v2_RS19845	COG1560	Kdo2-lipid A biosynthetic process
XCCCN07v2_RS19855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCCCN07v2_RS19890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCCCN07v2_RS19890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCCCN07v2_RS19900	COG0242	peptide deformylase activity
XCCCN07v2_RS19905	COG1652	LysM domain
XCCCN07v2_RS19910	COG0758	DNA mediated transformation
XCCCN07v2_RS19930	COG1754	DNA topoisomerase type I activity
XCCCN07v2_RS19930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN07v2_RS19950	COG5001	Diguanylate cyclase
XCCCN07v2_RS19950	COG4251	negative regulation of phosphorylation
XCCCN07v2_RS19950	COG3706	GGDEF domain
XCCCN07v2_RS19950	COG2203	Gaf domain
XCCCN07v2_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS19965	COG0616	signal peptide processing
XCCCN07v2_RS19970	COG0534	Mate efflux family protein
XCCCN07v2_RS19985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCCCN07v2_RS19990	COG0625	glutathione transferase activity
XCCCN07v2_RS20005	COG1252	NADH dehydrogenase
XCCCN07v2_RS20010	COG2860	membrane
XCCCN07v2_RS20015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN07v2_RS20025	COG2201	protein-glutamate methylesterase activity
XCCCN07v2_RS20030	COG2177	Part of the ABC transporter FtsEX involved in
XCCCN07v2_RS20035	COG2884	Cell division ATP-binding protein ftsE
XCCCN07v2_RS20045	COG3118	belongs to the thioredoxin family
XCCCN07v2_RS20050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCCCN07v2_RS20095	COG1473	amidohydrolase
XCCCN07v2_RS20100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN07v2_RS20130	COG4941	Belongs to the sigma-70 factor family
XCCCN07v2_RS20135	COG5383	Protein conserved in bacteria
XCCCN07v2_RS20175	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCCCN07v2_RS20180	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN07v2_RS20180	COG3501	Rhs element vgr protein
XCCCN07v2_RS20195	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCCCN07v2_RS20205	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN07v2_RS20215	COG0531	amino acid
XCCCN07v2_RS20230	COG4682	membrane
XCCCN07v2_RS20235	COG2133	pyrroloquinoline quinone binding
XCCCN07v2_RS20245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCCCN07v2_RS20260	COG1610	YqeY-like protein
XCCCN07v2_RS20265	COG1295	ribonuclease BN
XCCCN07v2_RS20270	COG0358	DNA primase activity
XCCCN07v2_RS20320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCCCN07v2_RS20335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCCCN07v2_RS20380	COG0739	heme binding
XCCCN07v2_RS20400	COG0708	Exodeoxyribonuclease III
XCCCN07v2_RS20415	COG1192	Involved in chromosome partitioning
XCCCN07v2_RS20420	COG1475	DNA binding
XCCCN07v2_RS20440	COG0463	Glycosyl transferase, family 2
XCCCN07v2_RS20465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCCCN07v2_RS20490	COG4221	oxidoreductase activity
XCCCN07v2_RS20495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCCCN07v2_RS20495	COG2755	lipolytic protein G-D-S-L family
XCCCN07v2_RS20515	COG1166	arginine decarboxylase activity
XCCCN07v2_RS20540	COG2960	long-chain fatty acid transporting porin activity
XCCCN07v2_RS20545	COG0606	chelatase, subunit chli
XCCCN07v2_RS20560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCCCN07v2_RS20600	COG1690	Belongs to the RtcB family
XCCCN07v2_RS20645	COG1090	epimerase
XCCCN07v2_RS20650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN07v2_RS20690	COG3039	Transposase
XCCCN07v2_RS20700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN07v2_RS20725	COG1011	Hydrolase
XCCCN07v2_RS20730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCCCN07v2_RS20750	COG2197	response regulator
XCCCN07v2_RS20755	COG4585	Histidine kinase
XCCCN07v2_RS20770	COG1136	(ABC) transporter
XCCCN07v2_RS20795	COG0697	spore germination
XCCCN07v2_RS20835	COG0180	Tryptophanyl-tRNA synthetase
XCCCN07v2_RS20840	COG3237	CsbD-like
XCCCN07v2_RS20915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCCCN07v2_RS20915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCCCN07v2_RS20925	COG3228	Belongs to the MtfA family
XCCCN07v2_RS20965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN07v2_RS20990	COG1199	ATP-dependent helicase activity
XCCCN07v2_RS21055	COG0625	glutathione transferase activity
XCCCN07v2_RS21090	COG4555	ABC transporter
XCCCN07v2_RS21100	COG1476	TRANSCRIPTIONal
XCCCN07v2_RS21115	COG1230	cation diffusion facilitator family transporter
XCCCN07v2_RS21125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN07v2_RS21130	COG1131	(ABC) transporter
XCCCN07v2_RS21135	COG0842	Transport permease protein
XCCCN07v2_RS21145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCCCN07v2_RS21155	COG1607	acyl-coa hydrolase
XCCCN07v2_RS21170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN07v2_RS21185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCCCN07v2_RS21185	COG1042	CoA-binding domain protein
XCCCN07v2_RS21185	COG0045	succinate-CoA ligase (ADP-forming) activity
XCCCN07v2_RS21190	COG2239	Acts as a magnesium transporter
XCCCN07v2_RS21205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN07v2_RS21210	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN07v2_RS21225	COG3100	YcgL domain-containing protein
XCCCN07v2_RS21230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCCCN07v2_RS21240	COG0463	Glycosyl transferase, family 2
XCCCN07v2_RS21260	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS21305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCCCN07v2_RS21375	COG0210	DNA helicase
XCCCN07v2_RS21385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS21390	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS21395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCCCN07v2_RS21405	COG2159	amidohydrolase
XCCCN07v2_RS21475	COG2091	lysine biosynthetic process via aminoadipic acid
XCCCN07v2_RS21535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCCCN07v2_RS21545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCCCN07v2_RS21550	COG3162	membrane
XCCCN07v2_RS21585	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN07v2_RS21600	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN07v2_RS21605	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCCCN07v2_RS21610	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN07v2_RS21615	COG3254	rhamnose metabolic process
XCCCN07v2_RS21625	COG1414	Transcriptional regulator
XCCCN07v2_RS21645	COG2205	protein histidine kinase activity
XCCCN07v2_RS21645	COG0784	Response regulator, receiver
XCCCN07v2_RS21650	COG3459	Glycosyltransferase 36 associated
XCCCN07v2_RS21655	COG2211	Major facilitator Superfamily
XCCCN07v2_RS21660	COG3265	gluconokinase activity
XCCCN07v2_RS21665	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN07v2_RS21685	COG2911	Protein conserved in bacteria
XCCCN07v2_RS21690	COG0729	surface antigen
XCCCN07v2_RS21705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN07v2_RS21710	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN07v2_RS21710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCCCN07v2_RS21740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCCCN07v2_RS21775	COG3661	Belongs to the glycosyl hydrolase 67 family
XCCCN07v2_RS21785	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN07v2_RS21795	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN07v2_RS21800	COG0246	Mannitol dehydrogenase
XCCCN07v2_RS21840	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN07v2_RS21855	COG3250	beta-galactosidase activity
XCCCN07v2_RS21865	COG3693	PFAM glycoside hydrolase, family 10
XCCCN07v2_RS21880	COG2211	Major facilitator Superfamily
XCCCN07v2_RS21920	COG2937	Belongs to the GPAT DAPAT family
XCCCN07v2_RS21975	COG0210	DNA helicase
XCCCN07v2_RS22060	COG3135	benzoate transporter
XCCCN07v2_RS22085	COG0676	glucose-6-phosphate 1-epimerase activity
XCCCN07v2_RS22105	COG0730	response to heat
XCCCN07v2_RS22135	COG0302	gtp cyclohydrolase
XCCCN07v2_RS22150	COG1566	PFAM secretion protein HlyD family protein
XCCCN07v2_RS22160	COG1289	transmembrane transporter activity
XCCCN07v2_RS22165	COG0477	Major facilitator Superfamily
XCCCN07v2_RS22175	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS22180	COG4221	oxidoreductase activity
XCCCN07v2_RS22185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN07v2_RS22255	COG0564	pseudouridine synthase activity
XCCCN07v2_RS22275	COG1192	Involved in chromosome partitioning
XCCCN07v2_RS22335	COG1074	ATP-dependent DNA helicase activity
XCCCN07v2_RS22340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCCCN07v2_RS22375	COG1127	ABC transporter
XCCCN07v2_RS22380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN07v2_RS22385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN07v2_RS22400	COG2853	Lipoprotein
XCCCN07v2_RS22405	COG0386	Belongs to the glutathione peroxidase family
XCCCN07v2_RS22415	COG1322	Protein conserved in bacteria
XCCCN07v2_RS22425	COG0604	alcohol dehydrogenase
XCCCN07v2_RS22430	COG0583	DNA-binding transcription factor activity
XCCCN07v2_RS22445	COG0531	amino acid
XCCCN07v2_RS22455	COG4206	TonB-dependent receptor
XCCCN07v2_RS22465	COG3706	GGDEF domain
XCCCN07v2_RS22470	COG3835	regulator
XCCCN07v2_RS22475	COG1929	Belongs to the glycerate kinase type-1 family
XCCCN07v2_RS22480	COG2271	Major facilitator Superfamily
XCCCN07v2_RS22500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCCCN07v2_RS22505	COG0861	Integral membrane protein TerC family
XCCCN07v2_RS22520	COG0584	glycerophosphoryl diester phosphodiesterase
XCCCN07v2_RS22540	COG0671	phosphoesterase, PA-phosphatase related
XCCCN07v2_RS22555	COG0726	polysaccharide deacetylase
XCCCN07v2_RS22560	COG0706	membrane insertase activity
XCCCN07v2_RS22575	COG3846	protein secretion by the type IV secretion system
XCCCN07v2_RS22610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN07v2_RS22735	COG0489	protein tyrosine kinase activity
XCCCN07v2_RS22805	COG4962	Type ii secretion system protein e
XCCCN07v2_RS22810	COG3838	Conjugal transfer protein Trbc
XCCCN07v2_RS22820	COG3451	type IV secretory pathway VirB4