locus-tag	class	description
JOA57_RS00020	COG0187	DNA topoisomerase II activity
JOA57_RS00030	COG0501	Belongs to the peptidase M48B family
JOA57_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JOA57_RS00105	COG0793	Belongs to the peptidase S41A family
JOA57_RS00110	COG4942	peptidase
JOA57_RS00120	COG2234	aminopeptidase activity
JOA57_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_RS00150	COG1064	alcohol dehydrogenase
JOA57_RS00165	COG0493	'glutamate synthase
JOA57_RS00170	COG0070	glutamate synthase
JOA57_RS00170	COG0067	glutamate synthase
JOA57_RS00170	COG0069	glutamate synthase activity
JOA57_RS00185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JOA57_RS00195	COG1741	Belongs to the pirin family
JOA57_RS00220	COG0583	DNA-binding transcription factor activity
JOA57_RS00280	COG1111	helicase
JOA57_RS00280	COG1205	dead DEAH box helicase
JOA57_RS00285	COG3177	Filamentation induced by cAMP protein fic
JOA57_RS00290	COG1272	protein, Hemolysin III
JOA57_RS00315	COG2249	NAD(P)H dehydrogenase (quinone) activity
JOA57_RS00325	COG1733	regulation of RNA biosynthetic process
JOA57_RS00370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOA57_RS00375	COG3237	CsbD-like
JOA57_RS00420	COG0628	permease
JOA57_RS00425	COG0657	acetylesterase activity
JOA57_RS00435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_RS00440	COG0477	Major facilitator Superfamily
JOA57_RS00485	COG0489	protein tyrosine kinase activity
JOA57_RS00625	COG0714	Associated with various cellular activities
JOA57_RS00670	COG4772	TonB-dependent receptor
JOA57_RS00685	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_RS00725	COG1755	Isoprenylcysteine carboxyl methyltransferase
JOA57_RS00730	COG4585	Histidine kinase
JOA57_RS00735	COG2197	response regulator
JOA57_RS00765	COG3710	Transcriptional regulator
JOA57_RS00785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_RS00830	COG3039	Transposase
JOA57_RS00855	COG0366	Alpha amylase catalytic
JOA57_RS00860	COG0366	Alpha amylase catalytic
JOA57_RS00900	COG2755	lipolytic protein G-D-S-L family
JOA57_RS00905	COG2272	Belongs to the type-B carboxylesterase lipase family
JOA57_RS00910	COG0657	acetylesterase activity
JOA57_RS00910	COG2755	lipolytic protein G-D-S-L family
JOA57_RS00920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JOA57_RS00935	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_RS00940	COG1609	Transcriptional regulator
JOA57_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS00960	COG2755	lipolytic protein G-D-S-L family
JOA57_RS00970	COG3186	Phenylalanine-4-hydroxylase
JOA57_RS00975	COG1522	sequence-specific DNA binding
JOA57_RS00985	COG1752	Esterase of the alpha-beta hydrolase superfamily
JOA57_RS01000	COG1119	ATPase activity
JOA57_RS01015	COG0517	IMP dehydrogenase activity
JOA57_RS01015	COG1125	glycine betaine transport
JOA57_RS01030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JOA57_RS01035	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JOA57_RS01065	COG0489	protein tyrosine kinase activity
JOA57_RS01070	COG0588	phosphoglycerate mutase activity
JOA57_RS01080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS01105	COG1881	PFAM PEBP family protein
JOA57_RS01120	COG0174	glutamine synthetase
JOA57_RS01125	COG0347	Belongs to the P(II) protein family
JOA57_RS01130	COG0004	ammonium transporteR
JOA57_RS01135	COG3852	Histidine kinase
JOA57_RS01140	COG2204	response regulator
JOA57_RS01150	COG2032	superoxide dismutase activity
JOA57_RS01155	COG2032	superoxide dismutase activity
JOA57_RS01160	COG0346	lactoylglutathione lyase activity
JOA57_RS01170	COG0183	Belongs to the thiolase family
JOA57_RS01210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOA57_RS01230	COG0028	Belongs to the TPP enzyme family
JOA57_RS01245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JOA57_RS01260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_RS01265	COG3177	Filamentation induced by cAMP protein fic
JOA57_RS01280	COG0596	Alpha beta hydrolase
JOA57_RS01285	COG0727	PFAM Uncharacterised protein family (UPF0153)
JOA57_RS01290	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_RS01295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOA57_RS01310	COG1181	Belongs to the D-alanine--D-alanine ligase family
JOA57_RS01325	COG0564	pseudouridine synthase activity
JOA57_RS01345	COG1446	asparaginase
JOA57_RS01350	COG0339	signal peptide processing
JOA57_RS01380	COG0583	DNA-binding transcription factor activity
JOA57_RS01385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JOA57_RS01390	COG2224	Isocitrate lyase
JOA57_RS01420	COG4770	biotin carboxylase activity
JOA57_RS01425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JOA57_RS01430	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS01495	COG0697	spore germination
JOA57_RS01505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JOA57_RS01515	COG1846	Transcriptional regulator
JOA57_RS01520	COG1764	response to oxidative stress
JOA57_RS01550	COG0656	L-ascorbic acid biosynthetic process
JOA57_RS01555	COG2130	NADP-dependent
JOA57_RS01570	COG1187	pseudouridine synthase activity
JOA57_RS01580	COG1643	Atp-dependent helicase
JOA57_RS01585	COG0840	transmembrane signaling receptor activity
JOA57_RS01590	COG4807	Protein conserved in bacteria
JOA57_RS01595	COG2351	hydroxyisourate hydrolase activity
JOA57_RS01600	COG2072	flavoprotein involved in K transport
JOA57_RS01620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JOA57_RS01645	COG3568	Endonuclease Exonuclease Phosphatase
JOA57_RS01650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS01665	COG1957	nucleoside hydrolase
JOA57_RS01675	COG2252	PERMEase
JOA57_RS01695	COG0084	hydrolase, TatD family'
JOA57_RS01705	COG0583	DNA-binding transcription factor activity
JOA57_RS01710	COG2814	Major facilitator Superfamily
JOA57_RS01735	COG1902	pentaerythritol trinitrate reductase activity
JOA57_RS01740	COG2084	Dehydrogenase
JOA57_RS01760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JOA57_RS01765	COG0583	DNA-binding transcription factor activity
JOA57_RS01795	COG0702	epimerase
JOA57_RS01800	COG1733	regulation of RNA biosynthetic process
JOA57_RS01810	COG0840	transmembrane signaling receptor activity
JOA57_RS01875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOA57_RS01935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JOA57_RS01960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOA57_RS01965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOA57_RS01975	COG3485	protocatechuate 3,4-dioxygenase
JOA57_RS01980	COG3485	protocatechuate 3,4-dioxygenase
JOA57_RS01990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOA57_RS01995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOA57_RS02005	COG1414	Transcriptional regulator
JOA57_RS02015	COG3039	Transposase
JOA57_RS02020	COG0657	acetylesterase activity
JOA57_RS02040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOA57_RS02090	COG1040	competence protein
JOA57_RS02105	COG0582	viral genome integration into host DNA
JOA57_RS02115	COG4774	siderophore transport
JOA57_RS02120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOA57_RS02135	COG4206	TonB-dependent receptor
JOA57_RS02165	COG1511	domain protein
JOA57_RS02165	COG3264	Mechanosensitive ion channel
JOA57_RS02170	COG1368	sulfuric ester hydrolase activity
JOA57_RS02175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JOA57_RS02180	COG2354	Protein conserved in bacteria
JOA57_RS02185	COG1649	PFAM Uncharacterised BCR, COG1649
JOA57_RS02195	COG0297	glycogen (starch) synthase activity
JOA57_RS02205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JOA57_RS02230	COG0702	epimerase
JOA57_RS02265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_RS02270	COG2085	NADP oxidoreductase coenzyme F420-dependent
JOA57_RS02285	COG0513	Belongs to the DEAD box helicase family
JOA57_RS02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOA57_RS02310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JOA57_RS02325	COG3104	oligopeptide transport
JOA57_RS02345	COG2852	Protein conserved in bacteria
JOA57_RS02375	COG1320	monovalent cation:proton antiporter activity
JOA57_RS02380	COG2212	antiporter activity
JOA57_RS02390	COG0651	ATP synthesis coupled electron transport
JOA57_RS02395	COG1006	Multisubunit Na H antiporter MnhC subunit
JOA57_RS02400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JOA57_RS02400	COG2111	Na H antiporter
JOA57_RS02415	COG3039	Transposase
JOA57_RS02480	COG0436	Aminotransferase
JOA57_RS02490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JOA57_RS02520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOA57_RS02625	COG2816	NAD+ diphosphatase activity
JOA57_RS02630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JOA57_RS02660	COG2814	Major facilitator Superfamily
JOA57_RS02670	COG1289	transmembrane transporter activity
JOA57_RS02675	COG0151	Belongs to the GarS family
JOA57_RS02690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOA57_RS02695	COG2267	carboxylic ester hydrolase activity
JOA57_RS02700	COG0671	phosphoesterase, PA-phosphatase related
JOA57_RS02700	COG2453	phosphatase
JOA57_RS02725	COG4589	Belongs to the CDS family
JOA57_RS02740	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JOA57_RS02775	COG0439	Biotin carboxylase
JOA57_RS02785	COG0511	ligase activity, forming carbon-carbon bonds
JOA57_RS02795	COG4232	protein-disulfide reductase activity
JOA57_RS02800	COG2356	endonuclease I
JOA57_RS02815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JOA57_RS02825	COG1196	nuclear chromosome segregation
JOA57_RS02865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JOA57_RS02890	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_RS02905	COG3712	iron ion homeostasis
JOA57_RS02945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOA57_RS02970	COG2353	YceI-like domain
JOA57_RS03025	COG1802	Transcriptional regulator
JOA57_RS03155	COG0435	Glutathione S-transferase
JOA57_RS03215	COG2409	Drug exporters of the RND superfamily
JOA57_RS03225	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_RS03225	COG1506	peptidase
JOA57_RS03240	COG1959	2 iron, 2 sulfur cluster binding
JOA57_RS03280	COG0697	spore germination
JOA57_RS03295	COG4305	rare lipoprotein A
JOA57_RS03300	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_RS03310	COG1113	amino acid transport
JOA57_RS03370	COG0840	transmembrane signaling receptor activity
JOA57_RS03375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_RS03375	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_RS03380	COG0659	secondary active sulfate transmembrane transporter activity
JOA57_RS03385	COG3706	GGDEF domain
JOA57_RS03400	COG0471	metal ion transport
JOA57_RS03400	COG3273	potassium ion transport
JOA57_RS03415	COG3275	phosphorelay sensor kinase activity
JOA57_RS03455	COG1505	serine-type exopeptidase activity
JOA57_RS03470	COG0436	Aminotransferase
JOA57_RS03480	COG2832	Protein of unknown function (DUF454)
JOA57_RS03550	COG2226	methyltransferase
JOA57_RS03555	COG5001	Diguanylate cyclase
JOA57_RS03555	COG3300	MHYT domain
JOA57_RS03560	COG0308	aminopeptidase N
JOA57_RS03595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JOA57_RS03610	COG3284	Transcriptional regulator
JOA57_RS03615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_RS03620	COG1077	Cell shape determining protein MreB Mrl
JOA57_RS03630	COG1792	Involved in formation and maintenance of cell shape
JOA57_RS03645	COG0772	Belongs to the SEDS family
JOA57_RS03655	COG3039	Transposase
JOA57_RS03665	COG3039	Transposase
JOA57_RS03690	COG2951	lytic endotransglycosylase activity
JOA57_RS03695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JOA57_RS03700	COG1686	Belongs to the peptidase S11 family
JOA57_RS03750	COG1056	cytidyltransferase-related domain
JOA57_RS03750	COG1051	belongs to the nudix hydrolase family
JOA57_RS03785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JOA57_RS03790	COG0673	inositol 2-dehydrogenase activity
JOA57_RS03795	COG2823	Periplasmic or secreted lipoprotein
JOA57_RS03800	COG4251	negative regulation of phosphorylation
JOA57_RS03805	COG0784	Response regulator, receiver
JOA57_RS03810	COG4191	Histidine kinase
JOA57_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOA57_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS03865	COG1459	type II secretion system
JOA57_RS03880	COG2165	general secretion pathway protein
JOA57_RS03885	COG4795	General secretion pathway protein
JOA57_RS03910	COG2188	Transcriptional regulator
JOA57_RS03920	COG1609	Transcriptional regulator
JOA57_RS03925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JOA57_RS03930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOA57_RS03970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JOA57_RS03980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JOA57_RS04005	COG2205	protein histidine kinase activity
JOA57_RS04025	COG0583	DNA-binding transcription factor activity
JOA57_RS04045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JOA57_RS04055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOA57_RS04070	COG0697	spore germination
JOA57_RS04080	COG1307	EDD domain protein, DegV family
JOA57_RS04120	COG0402	S-adenosylhomocysteine deaminase activity
JOA57_RS04140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JOA57_RS04160	COG0436	Aminotransferase
JOA57_RS04195	COG2211	Major facilitator Superfamily
JOA57_RS04200	COG1609	Transcriptional regulator
JOA57_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS04210	COG2851	Citrate transporter
JOA57_RS04225	COG0642	Histidine kinase
JOA57_RS04235	COG2197	response regulator
JOA57_RS04250	COG4191	Histidine kinase
JOA57_RS04290	COG1560	Kdo2-lipid A biosynthetic process
JOA57_RS04295	COG1519	Transferase
JOA57_RS04300	COG1538	Outer membrane efflux protein
JOA57_RS04305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JOA57_RS04315	COG3300	MHYT domain
JOA57_RS04315	COG5001	Diguanylate cyclase
JOA57_RS04325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOA57_RS04335	COG2226	methyltransferase
JOA57_RS04370	COG0405	Gamma-glutamyltransferase
JOA57_RS04375	COG0840	transmembrane signaling receptor activity
JOA57_RS04380	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_RS04380	COG1506	peptidase
JOA57_RS04380	COG4946	Tricorn protease homolog
JOA57_RS04390	COG3710	Transcriptional regulator
JOA57_RS04410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JOA57_RS04425	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JOA57_RS04455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JOA57_RS04465	COG3781	membrane
JOA57_RS04470	COG0671	phosphoesterase, PA-phosphatase related
JOA57_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS04490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOA57_RS04495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JOA57_RS04525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOA57_RS04555	COG1773	rubredoxin
JOA57_RS04560	COG2912	Transglutaminase-like superfamily
JOA57_RS04580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOA57_RS04605	COG0006	proline dipeptidase activity
JOA57_RS04630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JOA57_RS04640	COG0346	lactoylglutathione lyase activity
JOA57_RS04650	COG1561	YicC-like family, N-terminal region
JOA57_RS04665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOA57_RS04675	COG0583	DNA-binding transcription factor activity
JOA57_RS04690	COG2271	Major facilitator Superfamily
JOA57_RS04705	COG2721	sulfolactate sulfo-lyase activity
JOA57_RS04715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOA57_RS04740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JOA57_RS04770	COG0714	Associated with various cellular activities
JOA57_RS04790	COG2304	oxidoreductase activity
JOA57_RS04800	COG1301	dicarboxylic acid transport
JOA57_RS04805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOA57_RS04810	COG0596	Alpha beta hydrolase
JOA57_RS04815	COG4773	Receptor
JOA57_RS04820	COG0583	DNA-binding transcription factor activity
JOA57_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS04830	COG0739	heme binding
JOA57_RS04835	COG1376	ErfK ybiS ycfS ynhG family protein
JOA57_RS04880	COG4149	molybdate abc transporter
JOA57_RS04885	COG0725	ABC transporter, periplasmic molybdate-binding protein
JOA57_RS04905	COG3453	Protein conserved in bacteria
JOA57_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOA57_RS04920	COG3047	cAMP biosynthetic process
JOA57_RS04935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JOA57_RS04965	COG0469	pyruvate kinase activity
JOA57_RS04970	COG3588	fructose-bisphosphate aldolase
JOA57_RS04975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JOA57_RS05010	COG0784	Response regulator, receiver
JOA57_RS05010	COG2205	protein histidine kinase activity
JOA57_RS05010	COG2198	Histidine kinase
JOA57_RS05040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOA57_RS05050	COG0529	Catalyzes the synthesis of activated sulfate
JOA57_RS05050	COG2895	sulfate adenylyltransferase (ATP) activity
JOA57_RS05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_RS05060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_RS05065	COG0308	aminopeptidase N
JOA57_RS05075	COG1115	amino acid carrier protein
JOA57_RS05080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOA57_RS05095	COG3039	Transposase
JOA57_RS05100	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_RS05105	COG3250	beta-galactosidase activity
JOA57_RS05120	COG1609	Transcriptional regulator
JOA57_RS05150	COG0471	metal ion transport
JOA57_RS05150	COG3273	potassium ion transport
JOA57_RS05180	COG0582	viral genome integration into host DNA
JOA57_RS05200	COG1396	sequence-specific DNA binding
JOA57_RS05205	COG0583	DNA-binding transcription factor activity
JOA57_RS05220	COG3039	Transposase
JOA57_RS05265	COG3039	Transposase
JOA57_RS05295	COG0745	RESPONSE REGULATOR receiver
JOA57_RS05325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JOA57_RS05330	COG1459	type II secretion system
JOA57_RS05385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JOA57_RS05385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOA57_RS05395	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_RS05400	COG0564	pseudouridine synthase activity
JOA57_RS05420	COG0840	transmembrane signaling receptor activity
JOA57_RS05435	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_RS05440	COG1877	trehalose-phosphatase activity
JOA57_RS05485	COG1116	anion transmembrane transporter activity
JOA57_RS05490	COG0542	response to heat
JOA57_RS05505	COG4206	TonB-dependent receptor
JOA57_RS05525	COG1797	cobyrinic acid a,c-diamide synthase activity
JOA57_RS05530	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JOA57_RS05560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JOA57_RS05585	COG0019	diaminopimelate decarboxylase activity
JOA57_RS05590	COG4264	IucA IucC family
JOA57_RS05595	COG2814	Major facilitator Superfamily
JOA57_RS05600	COG4264	IucA IucC family
JOA57_RS05610	COG4772	TonB-dependent receptor
JOA57_RS05620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JOA57_RS05620	COG4651	solute:proton antiporter activity
JOA57_RS05650	COG0488	(ABC) transporter
JOA57_RS05670	COG2755	lipolytic protein G-D-S-L family
JOA57_RS05670	COG0657	acetylesterase activity
JOA57_RS05690	COG0477	Major facilitator Superfamily
JOA57_RS05760	COG0824	Thioesterase
JOA57_RS05770	COG0848	biopolymer transport protein
JOA57_RS05785	COG2885	chlorophyll binding
JOA57_RS05795	COG0602	queuosine metabolic process
JOA57_RS05840	COG0583	DNA-binding transcription factor activity
JOA57_RS05865	COG1187	pseudouridine synthase activity
JOA57_RS05880	COG0514	ATP-dependent DNA helicase (RecQ)
JOA57_RS05885	COG0783	Belongs to the Dps family
JOA57_RS05890	COG1643	Atp-dependent helicase
JOA57_RS05940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOA57_RS05950	COG1215	transferase activity, transferring glycosyl groups
JOA57_RS05955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOA57_RS05965	COG1199	ATP-dependent helicase activity
JOA57_RS05980	COG1397	ADP-ribosylglycohydrolase
JOA57_RS05990	COG0189	ligase activity
JOA57_RS06005	COG0835	chemotaxis
JOA57_RS06010	COG0840	transmembrane signaling receptor activity
JOA57_RS06015	COG0784	Response regulator, receiver
JOA57_RS06015	COG2198	Histidine kinase
JOA57_RS06015	COG0643	Histidine kinase
JOA57_RS06040	COG1595	DNA-templated transcription, initiation
JOA57_RS06045	COG2304	oxidoreductase activity
JOA57_RS06050	COG1446	asparaginase
JOA57_RS06105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JOA57_RS06120	COG3645	SOS response
JOA57_RS06160	COG3537	Alpha-1,2-mannosidase
JOA57_RS06170	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_RS06180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JOA57_RS06185	COG3858	chitin binding
JOA57_RS06185	COG1388	LysM domain
JOA57_RS06205	COG0837	glucose binding
JOA57_RS06210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JOA57_RS06220	COG0494	nUDIX hydrolase
JOA57_RS06225	COG1218	3'(2'),5'-bisphosphate nucleotidase
JOA57_RS06230	COG3956	TIGRFAM MazG family protein
JOA57_RS06240	COG0330	HflC and HflK could
JOA57_RS06285	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS06295	COG1309	transcriptional regulator
JOA57_RS06300	COG4771	TonB-dependent receptor
JOA57_RS06310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOA57_RS06320	COG0463	Glycosyl transferase, family 2
JOA57_RS06325	COG0516	GMP reductase activity
JOA57_RS06325	COG0517	IMP dehydrogenase activity
JOA57_RS06330	COG2982	Protein involved in outer membrane biogenesis
JOA57_RS06335	COG1272	protein, Hemolysin III
JOA57_RS06350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOA57_RS06355	COG0626	cystathionine gamma-synthase activity
JOA57_RS06360	COG0460	homoserine dehydrogenase
JOA57_RS06360	COG0527	aspartate kinase activity
JOA57_RS06375	COG1760	l-serine dehydratase
JOA57_RS06395	COG2353	YceI-like domain
JOA57_RS06415	COG0477	Major facilitator Superfamily
JOA57_RS06455	COG1842	Phage shock protein A
JOA57_RS06480	COG0754	glutathionylspermidine amidase activity
JOA57_RS06495	COG2814	Major facilitator Superfamily
JOA57_RS06560	COG0531	amino acid
JOA57_RS06565	COG2197	response regulator
JOA57_RS06585	COG1113	amino acid transport
JOA57_RS06590	COG1271	oxidase subunit
JOA57_RS06595	COG1294	oxidase, subunit
JOA57_RS06605	COG2239	Acts as a magnesium transporter
JOA57_RS06610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOA57_RS06615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_RS06635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_RS06650	COG1137	ATPase activity
JOA57_RS06665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JOA57_RS06675	COG0271	Belongs to the BolA IbaG family
JOA57_RS06700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOA57_RS06720	COG0628	permease
JOA57_RS06730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JOA57_RS06745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOA57_RS06750	COG1555	photosystem II stabilization
JOA57_RS06795	COG4774	siderophore transport
JOA57_RS06800	COG2146	nitrite reductase [NAD(P)H] activity
JOA57_RS06810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOA57_RS06815	COG0719	Fe-S assembly protein
JOA57_RS06820	COG0396	ATPase activity
JOA57_RS06825	COG0719	Fe-S assembly protein
JOA57_RS06875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOA57_RS06905	COG0519	Catalyzes the synthesis of GMP from XMP
JOA57_RS06910	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JOA57_RS06930	COG1764	response to oxidative stress
JOA57_RS06940	COG0384	phenazine biosynthesis protein PhzF
JOA57_RS06945	COG0384	phenazine biosynthesis protein PhzF
JOA57_RS06950	COG0527	aspartate kinase activity
JOA57_RS06975	COG0142	geranyltranstransferase activity
JOA57_RS06980	COG0629	single-stranded DNA binding
JOA57_RS06990	COG1401	restriction endodeoxyribonuclease activity
JOA57_RS06990	COG1401	restriction endodeoxyribonuclease activity
JOA57_RS06995	COG3039	Transposase
JOA57_RS07000	COG1401	restriction endodeoxyribonuclease activity
JOA57_RS07015	COG4251	negative regulation of phosphorylation
JOA57_RS07015	COG5001	Diguanylate cyclase
JOA57_RS07015	COG3706	GGDEF domain
JOA57_RS07015	COG2203	Gaf domain
JOA57_RS07020	COG0604	alcohol dehydrogenase
JOA57_RS07025	COG2080	2 iron, 2 sulfur cluster binding
JOA57_RS07030	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JOA57_RS07035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_RS07040	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOA57_RS07075	COG2879	small protein
JOA57_RS07080	COG1966	Carbon starvation protein
JOA57_RS07085	COG1741	Belongs to the pirin family
JOA57_RS07105	COG1741	Belongs to the pirin family
JOA57_RS07125	COG3590	peptidase
JOA57_RS07130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS07140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JOA57_RS07145	COG2202	Pas domain
JOA57_RS07145	COG2200	EAL domain
JOA57_RS07145	COG2199	diguanylate cyclase activity
JOA57_RS07150	COG0835	chemotaxis
JOA57_RS07155	COG0840	transmembrane signaling receptor activity
JOA57_RS07160	COG0643	Histidine kinase
JOA57_RS07160	COG2198	Histidine kinase
JOA57_RS07170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOA57_RS07185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JOA57_RS07190	COG0745	RESPONSE REGULATOR receiver
JOA57_RS07195	COG2205	protein histidine kinase activity
JOA57_RS07200	COG4452	Inner membrane protein CreD
JOA57_RS07235	COG0735	belongs to the Fur family
JOA57_RS07255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_RS07265	COG1309	transcriptional regulator
JOA57_RS07270	COG0667	Aldo Keto reductase
JOA57_RS07285	COG2207	Transcriptional regulator
JOA57_RS07305	COG0583	DNA-binding transcription factor activity
JOA57_RS07310	COG2814	Major facilitator Superfamily
JOA57_RS07330	COG1404	Belongs to the peptidase S8 family
JOA57_RS07340	COG3383	formate dehydrogenase (NAD+) activity
JOA57_RS07350	COG1271	oxidase subunit
JOA57_RS07355	COG1294	oxidase, subunit
JOA57_RS07450	COG5002	protein histidine kinase activity
JOA57_RS07450	COG5001	Diguanylate cyclase
JOA57_RS07455	COG1187	pseudouridine synthase activity
JOA57_RS07480	COG0475	glutathione-regulated potassium exporter activity
JOA57_RS07485	COG1132	(ABC) transporter
JOA57_RS07540	COG2155	Conserved Protein
JOA57_RS07550	COG3118	belongs to the thioredoxin family
JOA57_RS07575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOA57_RS07605	COG2968	Membrane
JOA57_RS07620	COG3164	Protein of unknown function
JOA57_RS07630	COG0312	modulator of DNA gyrase
JOA57_RS07640	COG0312	modulator of DNA gyrase
JOA57_RS07660	COG0142	geranyltranstransferase activity
JOA57_RS07675	COG1785	Belongs to the alkaline phosphatase family
JOA57_RS07680	COG1301	dicarboxylic acid transport
JOA57_RS07685	COG4106	trans-aconitate 2-methyltransferase activity
JOA57_RS07700	COG4191	Histidine kinase
JOA57_RS07705	COG3284	Transcriptional regulator
JOA57_RS07735	COG0791	NLP P60 protein
JOA57_RS07740	COG0791	NLP P60 protein
JOA57_RS07745	COG1047	Peptidyl-prolyl cis-trans
JOA57_RS07750	COG2311	Membrane
JOA57_RS07755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_RS07760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_RS07780	COG3590	peptidase
JOA57_RS07785	COG3590	peptidase
JOA57_RS07805	COG0489	protein tyrosine kinase activity
JOA57_RS07810	COG0717	Belongs to the dCTP deaminase family
JOA57_RS07845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_RS07860	COG0494	nUDIX hydrolase
JOA57_RS07875	COG0433	COG0433 Predicted ATPase
JOA57_RS07905	COG2890	protein-(glutamine-N5) methyltransferase activity
JOA57_RS07920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOA57_RS07925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOA57_RS08015	COG0300	oxidoreductase activity
JOA57_RS08035	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JOA57_RS08055	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JOA57_RS08060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JOA57_RS08100	COG1007	ATP synthesis coupled electron transport
JOA57_RS08115	COG0195	Participates in both transcription termination and antitermination
JOA57_RS08175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JOA57_RS08185	COG2095	MarC family integral membrane protein
JOA57_RS08195	COG1611	Belongs to the LOG family
JOA57_RS08200	COG4969	Belongs to the N-Me-Phe pilin family
JOA57_RS08255	COG3505	Type IV secretory pathway VirD4
JOA57_RS08275	COG2948	multi-organism process
JOA57_RS08295	COG3702	type iv secretory pathway
JOA57_RS08315	COG0366	Alpha amylase catalytic
JOA57_RS08335	COG1082	Xylose isomerase domain protein TIM barrel
JOA57_RS08365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOA57_RS08435	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS08440	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS08445	COG2244	polysaccharide biosynthetic process
JOA57_RS08450	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS08475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_RS08480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOA57_RS08485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOA57_RS08515	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS08540	COG0322	excinuclease ABC activity
JOA57_RS08560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JOA57_RS08570	COG4191	Histidine kinase
JOA57_RS08570	COG0784	Response regulator, receiver
JOA57_RS08590	COG0552	protein localization to endoplasmic reticulum
JOA57_RS08600	COG3938	Belongs to the proline racemase family
JOA57_RS08620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOA57_RS08630	COG0006	proline dipeptidase activity
JOA57_RS08650	COG0531	amino acid
JOA57_RS08685	COG4206	TonB-dependent receptor
JOA57_RS08695	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_RS08700	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_RS08700	COG1506	peptidase
JOA57_RS08710	COG4206	TonB-dependent receptor
JOA57_RS08725	COG0326	Molecular chaperone. Has ATPase activity
JOA57_RS08730	COG0742	ribosomal rna small subunit methyltransferase
JOA57_RS08750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JOA57_RS08755	COG0405	Gamma-glutamyltransferase
JOA57_RS08760	COG3291	Pkd domain containing protein
JOA57_RS08790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JOA57_RS08810	COG1862	Preprotein translocase
JOA57_RS08820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOA57_RS08835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOA57_RS08835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOA57_RS08840	COG1105	Belongs to the carbohydrate kinase PfkB family
JOA57_RS08845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOA57_RS08845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_RS08850	COG1609	Transcriptional regulator
JOA57_RS08860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_RS08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_RS08875	COG2902	Dehydrogenase
JOA57_RS08880	COG1609	Transcriptional regulator
JOA57_RS08880	COG2207	Transcriptional regulator
JOA57_RS08885	COG1335	isochorismatase
JOA57_RS08890	COG0477	Major facilitator Superfamily
JOA57_RS08905	COG2733	membrane
JOA57_RS08915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JOA57_RS08920	COG2223	nitrite transmembrane transporter activity
JOA57_RS08930	COG0243	molybdopterin cofactor binding
JOA57_RS08940	COG0477	Major facilitator Superfamily
JOA57_RS08945	COG2703	oxygen carrier activity
JOA57_RS08955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_RS08960	COG0174	glutamine synthetase
JOA57_RS08965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JOA57_RS09000	COG3842	ATPase activity
JOA57_RS09010	COG1176	ABC-type spermidine putrescine transport system, permease component I
JOA57_RS09015	COG1177	transmembrane transport
JOA57_RS09025	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_RS09040	COG4535	Mg2 and Co2 transporter CorC
JOA57_RS09060	COG1702	phosphate starvation-inducible protein PhoH
JOA57_RS09080	COG0741	lytic transglycosylase activity
JOA57_RS09085	COG0723	plastoquinol--plastocyanin reductase activity
JOA57_RS09090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JOA57_RS09095	COG2857	Cytochrome c1
JOA57_RS09100	COG0625	glutathione transferase activity
JOA57_RS09105	COG2969	positive regulation of protein catabolic process
JOA57_RS09120	COG1201	RNA secondary structure unwinding
JOA57_RS09130	COG0840	transmembrane signaling receptor activity
JOA57_RS09135	COG0835	chemotaxis
JOA57_RS09175	COG0582	viral genome integration into host DNA
JOA57_RS09205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JOA57_RS09220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOA57_RS09225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOA57_RS09225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JOA57_RS09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOA57_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS09275	COG5001	Diguanylate cyclase
JOA57_RS09275	COG3300	MHYT domain
JOA57_RS09280	COG2081	HI0933 family
JOA57_RS09285	COG4681	YaeQ
JOA57_RS09325	COG0513	Belongs to the DEAD box helicase family
JOA57_RS09330	COG0488	(ABC) transporter
JOA57_RS09345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOA57_RS09350	COG0483	inositol monophosphate 1-phosphatase activity
JOA57_RS09365	COG5001	Diguanylate cyclase
JOA57_RS09365	COG3300	MHYT domain
JOA57_RS09370	COG1509	lysine 2,3-aminomutase activity
JOA57_RS09385	COG0402	S-adenosylhomocysteine deaminase activity
JOA57_RS09435	COG4302	ethanolamine ammonia-lyase activity
JOA57_RS09455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JOA57_RS09480	COG2166	iron-sulfur cluster assembly
JOA57_RS09495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOA57_RS09505	COG0137	argininosuccinate synthase activity
JOA57_RS09510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOA57_RS09515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JOA57_RS09545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOA57_RS09585	COG1294	oxidase, subunit
JOA57_RS09595	COG4988	ABC transporter
JOA57_RS09600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JOA57_RS09665	COG0436	Aminotransferase
JOA57_RS09690	COG1187	pseudouridine synthase activity
JOA57_RS09695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOA57_RS09700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOA57_RS09705	COG2350	Protein conserved in bacteria
JOA57_RS09730	COG2182	Extracellular solute-binding protein
JOA57_RS09740	COG0395	ABC-type sugar transport system, permease component
JOA57_RS09765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOA57_RS09770	COG2957	Belongs to the agmatine deiminase family
JOA57_RS09790	COG0539	negative regulation of cytoplasmic translation
JOA57_RS09805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JOA57_RS09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JOA57_RS09825	COG0475	glutathione-regulated potassium exporter activity
JOA57_RS09825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JOA57_RS09865	COG2197	response regulator
JOA57_RS09880	COG1335	isochorismatase
JOA57_RS09895	COG2814	Major facilitator Superfamily
JOA57_RS09910	COG1914	H( )-stimulated, divalent metal cation uptake system
JOA57_RS09930	COG0668	transmembrane transport
JOA57_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS09960	COG1183	phosphatidylcholine synthase activity
JOA57_RS09970	COG3243	poly(R)-hydroxyalkanoic acid synthase
JOA57_RS09985	COG0723	plastoquinol--plastocyanin reductase activity
JOA57_RS09985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_RS09995	COG2183	response to ionizing radiation
JOA57_RS10000	COG5001	Diguanylate cyclase
JOA57_RS10065	COG0800	Aldolase
JOA57_RS10070	COG0129	dihydroxy-acid dehydratase activity
JOA57_RS10075	COG0363	glucosamine-6-phosphate deaminase activity
JOA57_RS10085	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOA57_RS10095	COG0354	folic acid binding
JOA57_RS10110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JOA57_RS10115	COG1053	succinate dehydrogenase
JOA57_RS10125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JOA57_RS10140	COG4591	ABC-type transport system involved in lipoprotein release permease component
JOA57_RS10160	COG0811	peptide transport
JOA57_RS10185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOA57_RS10200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOA57_RS10230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JOA57_RS10265	COG1530	ribonuclease E activity
JOA57_RS10275	COG0428	transporter
JOA57_RS10420	COG0420	3'-5' exonuclease activity
JOA57_RS10425	COG1196	nuclear chromosome segregation
JOA57_RS10480	COG1192	Involved in chromosome partitioning
JOA57_RS10485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JOA57_RS10650	COG3279	Response regulator of the LytR AlgR family
JOA57_RS10660	COG3459	Glycosyltransferase 36 associated
JOA57_RS10670	COG0784	Response regulator, receiver
JOA57_RS10670	COG4191	Histidine kinase
JOA57_RS10690	COG0840	transmembrane signaling receptor activity
JOA57_RS10700	COG1238	metal cluster binding
JOA57_RS10730	COG1733	regulation of RNA biosynthetic process
JOA57_RS10745	COG1999	signal sequence binding
JOA57_RS10760	COG3590	peptidase
JOA57_RS10825	COG5001	Diguanylate cyclase
JOA57_RS10835	COG2201	protein-glutamate methylesterase activity
JOA57_RS10840	COG3685	Protein conserved in bacteria
JOA57_RS10855	COG0579	oxidoreductase
JOA57_RS10865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JOA57_RS10875	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JOA57_RS10895	COG0243	molybdopterin cofactor binding
JOA57_RS10905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOA57_RS10910	COG2223	nitrite transmembrane transporter activity
JOA57_RS10915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JOA57_RS10925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JOA57_RS10925	COG1648	precorrin-2 dehydrogenase activity
JOA57_RS10935	COG0746	molybdenum cofactor guanylyltransferase activity
JOA57_RS10940	COG0303	'Molybdopterin
JOA57_RS10950	COG0708	Exodeoxyribonuclease III
JOA57_RS10975	COG2124	cytochrome p450
JOA57_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS10995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOA57_RS11010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_RS11045	COG1024	Enoyl-CoA hydratase
JOA57_RS11045	COG1250	3-hydroxyacyl-CoA dehydrogenase
JOA57_RS11050	COG0183	Belongs to the thiolase family
JOA57_RS11055	COG0038	chloride channel
JOA57_RS11060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JOA57_RS11080	COG1674	ftsk spoiiie
JOA57_RS11085	COG0492	ferredoxin-NADP+ reductase activity
JOA57_RS11105	COG0542	response to heat
JOA57_RS11125	COG2915	High frequency lysogenization protein hflD homolog
JOA57_RS11160	COG4191	Histidine kinase
JOA57_RS11180	COG0835	chemotaxis
JOA57_RS11180	COG0784	Response regulator, receiver
JOA57_RS11190	COG1558	bacterial-type flagellum-dependent cell motility
JOA57_RS11195	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JOA57_RS11205	COG4787	bacterial-type flagellum-dependent cell motility
JOA57_RS11225	COG3951	Flagellar rod assembly protein muramidase FlgJ
JOA57_RS11225	COG1705	Flagellar rod assembly protein muramidase FlgJ
JOA57_RS11235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOA57_RS11240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOA57_RS11245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOA57_RS11275	COG2201	protein-glutamate methylesterase activity
JOA57_RS11305	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS11305	COG1216	Glycosyl transferase, family 2
JOA57_RS11310	COG1677	Flagellar hook-basal body complex protein FliE
JOA57_RS11380	COG1684	flagellar biosynthetic protein fliR
JOA57_RS11435	COG2198	Histidine kinase
JOA57_RS11435	COG0643	Histidine kinase
JOA57_RS11435	COG0784	Response regulator, receiver
JOA57_RS11500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JOA57_RS11505	COG1360	Flagellar Motor Protein
JOA57_RS11510	COG1192	Involved in chromosome partitioning
JOA57_RS11515	COG0835	chemotaxis
JOA57_RS11525	COG0745	RESPONSE REGULATOR receiver
JOA57_RS11535	COG0840	transmembrane signaling receptor activity
JOA57_RS11545	COG0840	transmembrane signaling receptor activity
JOA57_RS11550	COG0840	transmembrane signaling receptor activity
JOA57_RS11560	COG0840	transmembrane signaling receptor activity
JOA57_RS11565	COG0840	transmembrane signaling receptor activity
JOA57_RS11570	COG0840	transmembrane signaling receptor activity
JOA57_RS11575	COG0840	transmembrane signaling receptor activity
JOA57_RS11585	COG0840	transmembrane signaling receptor activity
JOA57_RS11595	COG0835	chemotaxis
JOA57_RS11605	COG0840	transmembrane signaling receptor activity
JOA57_RS11630	COG2267	carboxylic ester hydrolase activity
JOA57_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_RS11665	COG1024	Enoyl-CoA hydratase
JOA57_RS11670	COG2205	protein histidine kinase activity
JOA57_RS11670	COG2198	Histidine kinase
JOA57_RS11670	COG0784	Response regulator, receiver
JOA57_RS11675	COG2198	Histidine kinase
JOA57_RS11675	COG2205	protein histidine kinase activity
JOA57_RS11675	COG0784	Response regulator, receiver
JOA57_RS11695	COG3279	Response regulator of the LytR AlgR family
JOA57_RS11715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JOA57_RS11725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_RS11730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JOA57_RS11740	COG0505	Belongs to the CarA family
JOA57_RS11750	COG2258	MOSC domain
JOA57_RS11755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOA57_RS11780	COG1024	Enoyl-CoA hydratase
JOA57_RS11815	COG0277	FAD linked oxidase domain protein
JOA57_RS11820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JOA57_RS11835	COG0531	amino acid
JOA57_RS11840	COG0531	amino acid
JOA57_RS11870	COG0140	phosphoribosyl-ATP diphosphatase activity
JOA57_RS11870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JOA57_RS11890	COG0131	Imidazoleglycerol-phosphate dehydratase
JOA57_RS11890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JOA57_RS11905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JOA57_RS11920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOA57_RS11930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOA57_RS11940	COG0083	homoserine kinase activity
JOA57_RS11980	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_RS12005	COG0697	spore germination
JOA57_RS12010	COG1794	racemase activity, acting on amino acids and derivatives
JOA57_RS12020	COG0671	phosphoesterase, PA-phosphatase related
JOA57_RS12035	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JOA57_RS12040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_RS12045	COG2203	Gaf domain
JOA57_RS12045	COG3706	GGDEF domain
JOA57_RS12045	COG4251	negative regulation of phosphorylation
JOA57_RS12045	COG5001	Diguanylate cyclase
JOA57_RS12055	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_RS12110	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOA57_RS12130	COG0477	Major facilitator Superfamily
JOA57_RS12140	COG1070	Carbohydrate kinase
JOA57_RS12150	COG1501	Belongs to the glycosyl hydrolase 31 family
JOA57_RS12190	COG0800	Aldolase
JOA57_RS12205	COG3734	2-keto-3-deoxy-galactonokinase
JOA57_RS12210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JOA57_RS12220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOA57_RS12235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOA57_RS12240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JOA57_RS12250	COG0352	thiamine-phosphate diphosphorylase activity
JOA57_RS12250	COG0351	phosphomethylpyrimidine kinase
JOA57_RS12275	COG0583	DNA-binding transcription factor activity
JOA57_RS12280	COG1741	Belongs to the pirin family
JOA57_RS12315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOA57_RS12325	COG4771	TonB-dependent receptor
JOA57_RS12335	COG1546	Belongs to the CinA family
JOA57_RS12340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOA57_RS12355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOA57_RS12360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOA57_RS12370	COG1534	Rna-binding protein
JOA57_RS12385	COG1238	metal cluster binding
JOA57_RS12400	COG2840	Smr protein MutS2
JOA57_RS12460	COG2134	cdp-diacylglycerol pyrophosphatase
JOA57_RS12485	COG1253	flavin adenine dinucleotide binding
JOA57_RS12500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOA57_RS12505	COG0477	Major facilitator Superfamily
JOA57_RS12510	COG1132	(ABC) transporter
JOA57_RS12530	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS12535	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS12540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JOA57_RS12570	COG2244	polysaccharide biosynthetic process
JOA57_RS12585	COG3038	cytochrome b561
JOA57_RS12620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOA57_RS12640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_RS12655	COG0784	Response regulator, receiver
JOA57_RS12655	COG4191	Histidine kinase
JOA57_RS12660	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JOA57_RS12710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JOA57_RS12745	COG0583	DNA-binding transcription factor activity
JOA57_RS12760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JOA57_RS12770	COG0077	Prephenate dehydratase
JOA57_RS12770	COG1605	Chorismate mutase
JOA57_RS12780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOA57_RS12835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JOA57_RS12845	COG4993	Dehydrogenase
JOA57_RS12865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JOA57_RS12875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOA57_RS12915	COG0316	Belongs to the HesB IscA family
JOA57_RS12945	COG0288	reversible hydration of carbon dioxide
JOA57_RS12970	COG2925	Exonuclease
JOA57_RS12985	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOA57_RS13005	COG0488	(ABC) transporter
JOA57_RS13010	COG2264	protein methyltransferase activity
JOA57_RS13045	COG0494	nUDIX hydrolase
JOA57_RS13055	COG1024	Enoyl-CoA hydratase
JOA57_RS13065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOA57_RS13070	COG0659	secondary active sulfate transmembrane transporter activity
JOA57_RS13095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JOA57_RS13100	COG0573	inorganic phosphate transmembrane transporter activity
JOA57_RS13105	COG0581	inorganic phosphate transmembrane transporter activity
JOA57_RS13115	COG0704	Plays a role in the regulation of phosphate uptake
JOA57_RS13135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOA57_RS13145	COG0557	exoribonuclease II activity
JOA57_RS13160	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS13165	COG2226	methyltransferase
JOA57_RS13170	COG0646	methionine synthase
JOA57_RS13170	COG1410	methionine synthase
JOA57_RS13175	COG1410	methionine synthase
JOA57_RS13175	COG0646	methionine synthase
JOA57_RS13185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_RS13195	COG1609	Transcriptional regulator
JOA57_RS13235	COG0386	Belongs to the glutathione peroxidase family
JOA57_RS13245	COG1725	Transcriptional regulator
JOA57_RS13250	COG1131	(ABC) transporter
JOA57_RS13295	COG2850	peptidyl-arginine hydroxylation
JOA57_RS13330	COG1132	(ABC) transporter
JOA57_RS13335	COG0583	DNA-binding transcription factor activity
JOA57_RS13340	COG2274	protein secretion by the type I secretion system
JOA57_RS13365	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JOA57_RS13385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOA57_RS13390	COG1420	regulation of RNA biosynthetic process
JOA57_RS13395	COG0497	DNA recombination
JOA57_RS13405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_RS13425	COG1404	Belongs to the peptidase S8 family
JOA57_RS13495	COG3706	GGDEF domain
JOA57_RS13515	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS13525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_RS13535	COG0583	DNA-binding transcription factor activity
JOA57_RS13545	COG0415	Belongs to the DNA photolyase family
JOA57_RS13550	COG0305	Participates in initiation and elongation during chromosome replication
JOA57_RS13560	COG0367	asparagine synthase
JOA57_RS13575	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS13590	COG0084	hydrolase, TatD family'
JOA57_RS13595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JOA57_RS13655	COG0386	Belongs to the glutathione peroxidase family
JOA57_RS13660	COG0339	signal peptide processing
JOA57_RS13695	COG3104	oligopeptide transport
JOA57_RS13725	COG2814	Major facilitator Superfamily
JOA57_RS13730	COG1566	PFAM secretion protein HlyD family protein
JOA57_RS13770	COG4774	siderophore transport
JOA57_RS13780	COG0367	asparagine synthase
JOA57_RS13795	COG1393	Belongs to the ArsC family
JOA57_RS13865	COG0528	UMP kinase activity
JOA57_RS13875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOA57_RS13880	COG0575	Belongs to the CDS family
JOA57_RS13890	COG0750	zinc metalloprotease
JOA57_RS13945	COG1981	membrane
JOA57_RS13970	COG1695	Transcriptional regulator
JOA57_RS13995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOA57_RS14005	COG2040	homocysteine
JOA57_RS14010	COG0833	amino acid
JOA57_RS14020	COG0346	lactoylglutathione lyase activity
JOA57_RS14045	COG2878	Part of a membrane complex involved in electron transport
JOA57_RS14060	COG1595	DNA-templated transcription, initiation
JOA57_RS14085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JOA57_RS14100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JOA57_RS14105	COG0251	oxidation-reduction process
JOA57_RS14115	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOA57_RS14115	COG0392	lysyltransferase activity
JOA57_RS14150	COG2814	Major facilitator Superfamily
JOA57_RS14155	COG1902	pentaerythritol trinitrate reductase activity
JOA57_RS14185	COG2824	Alkylphosphonate utilization operon protein PhnA
JOA57_RS14195	COG1047	Peptidyl-prolyl cis-trans
JOA57_RS14240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JOA57_RS14250	COG5487	UPF0391 membrane protein
JOA57_RS14255	COG1451	nucleotide metabolic process
JOA57_RS14275	COG0183	Belongs to the thiolase family
JOA57_RS14310	COG1793	dna ligase
JOA57_RS14310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JOA57_RS14320	COG1793	dna ligase
JOA57_RS14325	COG1201	RNA secondary structure unwinding
JOA57_RS14335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_RS14340	COG1278	Cold shock
JOA57_RS14345	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOA57_RS14350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JOA57_RS14360	COG3046	protein related to deoxyribodipyrimidine photolyase
JOA57_RS14365	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
JOA57_RS14370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JOA57_RS14375	COG2954	triphosphatase activity
JOA57_RS14425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOA57_RS14460	COG1024	Enoyl-CoA hydratase
JOA57_RS14465	COG1960	acyl-CoA dehydrogenase activity
JOA57_RS14475	COG3800	Transcriptional regulator
JOA57_RS14475	COG1396	sequence-specific DNA binding
JOA57_RS14485	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JOA57_RS14490	COG3250	beta-galactosidase activity
JOA57_RS14535	COG3039	Transposase
JOA57_RS14545	COG3039	Transposase
JOA57_RS14630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOA57_RS14685	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_RS14705	COG1309	transcriptional regulator
JOA57_RS14710	COG0436	Aminotransferase
JOA57_RS14720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOA57_RS14740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOA57_RS14760	COG0534	Mate efflux family protein
JOA57_RS14790	COG2070	2-Nitropropane dioxygenase
JOA57_RS14805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOA57_RS14810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOA57_RS14820	COG3534	alpha-L-arabinofuranosidase
JOA57_RS14850	COG0784	Response regulator, receiver
JOA57_RS14850	COG4191	Histidine kinase
JOA57_RS14855	COG4999	Histidine kinase
JOA57_RS14855	COG3850	Histidine kinase
JOA57_RS14855	COG3437	response regulator, receiver
JOA57_RS14855	COG2205	protein histidine kinase activity
JOA57_RS14860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JOA57_RS14870	COG2205	protein histidine kinase activity
JOA57_RS14875	COG5507	3-demethylubiquinone-9 3-methyltransferase
JOA57_RS14890	COG4771	TonB-dependent receptor
JOA57_RS14915	COG2172	sigma factor antagonist activity
JOA57_RS14920	COG1366	Belongs to the anti-sigma-factor antagonist family
JOA57_RS14925	COG1366	Belongs to the anti-sigma-factor antagonist family
JOA57_RS14930	COG1902	pentaerythritol trinitrate reductase activity
JOA57_RS14940	COG0326	Molecular chaperone. Has ATPase activity
JOA57_RS14945	COG2207	Transcriptional regulator
JOA57_RS14955	COG3152	Membrane
JOA57_RS14970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JOA57_RS14975	COG1845	cytochrome c oxidase, subunit III
JOA57_RS14980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOA57_RS15010	COG0196	riboflavin kinase activity
JOA57_RS15040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JOA57_RS15045	COG0824	Thioesterase
JOA57_RS15050	COG1024	Enoyl-CoA hydratase
JOA57_RS15055	COG1946	Acyl-CoA thioesterase
JOA57_RS15070	COG1595	DNA-templated transcription, initiation
JOA57_RS15130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOA57_RS15160	COG2197	response regulator
JOA57_RS15165	COG4585	Histidine kinase
JOA57_RS15180	COG2894	cell division
JOA57_RS15195	COG5002	protein histidine kinase activity
JOA57_RS15200	COG0745	RESPONSE REGULATOR receiver
JOA57_RS15235	COG2814	Major facilitator Superfamily
JOA57_RS15255	COG0656	L-ascorbic acid biosynthetic process
JOA57_RS15260	COG0753	catalase activity
JOA57_RS15275	COG1917	Cupin 2, conserved barrel domain protein
JOA57_RS15275	COG2207	Transcriptional regulator
JOA57_RS15295	COG1506	peptidase
JOA57_RS15295	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_RS15305	COG1297	OPT oligopeptide transporter protein
JOA57_RS15330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOA57_RS15360	COG2080	2 iron, 2 sulfur cluster binding
JOA57_RS15365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JOA57_RS15370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS15420	COG3537	Alpha-1,2-mannosidase
JOA57_RS15430	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS15435	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_RS15445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JOA57_RS15515	COG3039	Transposase
JOA57_RS15530	COG0308	aminopeptidase N
JOA57_RS15545	COG0330	HflC and HflK could
JOA57_RS15550	COG0330	HflC and HflK could
JOA57_RS15570	COG0678	peroxiredoxin activity
JOA57_RS15580	COG4953	penicillin-binding protein 1C
JOA57_RS15605	COG2373	Large extracellular alpha-helical protein
JOA57_RS15635	COG3609	addiction module antidote protein, CC2985 family
JOA57_RS15655	COG3829	transcription factor binding
JOA57_RS15695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOA57_RS15700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOA57_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS15720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JOA57_RS15725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_RS15735	COG1399	metal-binding, possibly nucleic acid-binding protein
JOA57_RS15770	COG0714	Associated with various cellular activities
JOA57_RS15790	COG0537	adenosine 5'-monophosphoramidase activity
JOA57_RS15820	COG0314	molybdopterin synthase activity
JOA57_RS15825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOA57_RS15845	COG1234	tRNA 3'-trailer cleavage
JOA57_RS15855	COG0859	PFAM glycosyl transferase family 9
JOA57_RS15870	COG0631	protein serine/threonine phosphatase activity
JOA57_RS15875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JOA57_RS15975	COG0473	3-isopropylmalate dehydrogenase activity
JOA57_RS15990	COG4783	chaperone-mediated protein folding
JOA57_RS15995	COG0745	RESPONSE REGULATOR receiver
JOA57_RS16005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JOA57_RS16015	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS16020	COG0671	phosphoesterase, PA-phosphatase related
JOA57_RS16025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JOA57_RS16035	COG3291	Pkd domain containing protein
JOA57_RS16040	COG2833	Protein of unknown function (DUF455)
JOA57_RS16060	COG0285	dihydrofolate synthase activity
JOA57_RS16075	COG0406	alpha-ribazole phosphatase activity
JOA57_RS16100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JOA57_RS16105	COG4208	sulfate ABC transporter
JOA57_RS16110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JOA57_RS16115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JOA57_RS16150	COG1902	pentaerythritol trinitrate reductase activity
JOA57_RS16150	COG0446	pyridine nucleotide-disulphide oxidoreductase
JOA57_RS16175	COG0625	glutathione transferase activity
JOA57_RS16185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOA57_RS16190	COG1217	gtp-binding protein TYPA
JOA57_RS16200	COG0154	amidase activity
JOA57_RS16210	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JOA57_RS16245	COG0201	protein transport
JOA57_RS16330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOA57_RS16405	COG0250	Participates in transcription elongation, termination and antitermination
JOA57_RS16440	COG0012	GTP binding
JOA57_RS16445	COG0193	aminoacyl-tRNA hydrolase activity
JOA57_RS16455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOA57_RS16495	COG0521	Mo-molybdopterin cofactor biosynthetic process
JOA57_RS16515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_RS16545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOA57_RS16550	COG1404	Belongs to the peptidase S8 family
JOA57_RS16560	COG1404	Belongs to the peptidase S8 family
JOA57_RS16565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOA57_RS16630	COG0778	Nitroreductase
JOA57_RS16635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOA57_RS16635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOA57_RS16655	COG2890	protein-(glutamine-N5) methyltransferase activity
JOA57_RS16665	COG3634	alkyl hydroperoxide reductase activity
JOA57_RS16670	COG0583	DNA-binding transcription factor activity
JOA57_RS16675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_RS16700	COG2197	response regulator
JOA57_RS16705	COG0784	Response regulator, receiver
JOA57_RS16705	COG2205	protein histidine kinase activity
JOA57_RS16705	COG5002	protein histidine kinase activity
JOA57_RS16735	COG0697	spore germination
JOA57_RS16765	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_RS16785	COG1024	Enoyl-CoA hydratase
JOA57_RS16795	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_RS16800	COG0583	DNA-binding transcription factor activity
JOA57_RS16805	COG3384	dioxygenase
JOA57_RS16835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_RS16840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_RS16850	COG2096	Adenosyltransferase
JOA57_RS16855	COG0123	including yeast histone deacetylase and acetoin utilization protein
JOA57_RS16885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JOA57_RS16920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JOA57_RS16930	COG0642	Histidine kinase
JOA57_RS16945	COG4181	ATPase activity
JOA57_RS16955	COG2175	clavaminate synthase activity
JOA57_RS16965	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JOA57_RS16970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JOA57_RS16990	COG4771	TonB-dependent receptor
JOA57_RS17005	COG0667	Aldo Keto reductase
JOA57_RS17010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOA57_RS17020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOA57_RS17075	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JOA57_RS17115	COG0366	Alpha amylase catalytic
JOA57_RS17150	COG0604	alcohol dehydrogenase
JOA57_RS17150	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS17150	COG3321	synthase
JOA57_RS17165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JOA57_RS17180	COG0494	nUDIX hydrolase
JOA57_RS17195	COG0739	heme binding
JOA57_RS17220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JOA57_RS17225	COG1181	Belongs to the D-alanine--D-alanine ligase family
JOA57_RS17250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JOA57_RS17265	COG3116	cell division
JOA57_RS17315	COG1988	membrane-bound metal-dependent
JOA57_RS17320	COG0277	FAD linked oxidase domain protein
JOA57_RS17330	COG0745	RESPONSE REGULATOR receiver
JOA57_RS17335	COG2205	protein histidine kinase activity
JOA57_RS17345	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JOA57_RS17350	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JOA57_RS17365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOA57_RS17395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOA57_RS17395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOA57_RS17420	COG0488	(ABC) transporter
JOA57_RS17425	COG0242	peptide deformylase activity
JOA57_RS17430	COG1393	Belongs to the ArsC family
JOA57_RS17450	COG0457	Tetratricopeptide repeat
JOA57_RS17500	COG2188	Transcriptional regulator
JOA57_RS17510	COG1450	Type ii and iii secretion system protein
JOA57_RS17525	COG3166	PFAM Fimbrial assembly family protein
JOA57_RS17530	COG3156	type II secretion system protein K
JOA57_RS17535	COG4795	General secretion pathway protein
JOA57_RS17540	COG2165	general secretion pathway protein
JOA57_RS17545	COG4970	Tfp pilus assembly protein FimT
JOA57_RS17550	COG2165	general secretion pathway protein
JOA57_RS17555	COG1459	type II secretion system
JOA57_RS17560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOA57_RS17565	COG1404	Belongs to the peptidase S8 family
JOA57_RS17580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOA57_RS17580	COG0047	phosphoribosylformylglycinamidine synthase activity
JOA57_RS17585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JOA57_RS17590	COG4974	Belongs to the 'phage' integrase family
JOA57_RS17605	COG0795	lipopolysaccharide-transporting ATPase activity
JOA57_RS17665	COG1183	phosphatidylcholine synthase activity
JOA57_RS17690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JOA57_RS17695	COG1127	ABC transporter
JOA57_RS17700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JOA57_RS17700	COG3218	ABC-type transport auxiliary lipoprotein component
JOA57_RS17725	COG3754	Rhamnan synthesis protein F
JOA57_RS17730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOA57_RS17735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOA57_RS17740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOA57_RS17745	COG0662	Cupin 2, conserved barrel domain protein
JOA57_RS17745	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JOA57_RS17770	COG2086	electron transfer activity
JOA57_RS17785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOA57_RS17790	COG0463	Glycosyl transferase, family 2
JOA57_RS17815	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JOA57_RS17830	COG0438	transferase activity, transferring glycosyl groups
JOA57_RS17855	COG0626	cystathionine gamma-synthase activity
JOA57_RS17885	COG0625	glutathione transferase activity
JOA57_RS17895	COG0513	Belongs to the DEAD box helicase family
JOA57_RS17900	COG0720	synthase
JOA57_RS17910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JOA57_RS17915	COG1956	GAF domain-containing protein
JOA57_RS17945	COG0339	signal peptide processing
JOA57_RS17950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JOA57_RS18000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JOA57_RS18010	COG1136	(ABC) transporter
JOA57_RS18015	COG0577	efflux transmembrane transporter activity
JOA57_RS18035	COG4191	Histidine kinase
JOA57_RS18100	COG0356	it plays a direct role in the translocation of protons across the membrane
JOA57_RS18115	COG1228	amidohydrolase
JOA57_RS18120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_RS18130	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOA57_RS18170	COG2011	ABC-type metal ion transport system permease component
JOA57_RS18180	COG0697	spore germination
JOA57_RS18215	COG1187	pseudouridine synthase activity
JOA57_RS18220	COG2813	Specifically methylates the guanine in position
JOA57_RS18240	COG5002	protein histidine kinase activity
JOA57_RS18320	COG0842	Transport permease protein
JOA57_RS18325	COG1131	(ABC) transporter
JOA57_RS18330	COG0025	NhaP-type Na H and K H
JOA57_RS18335	COG3795	YCII-related domain
JOA57_RS18340	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JOA57_RS18345	COG1573	uracil-dna glycosylase
JOA57_RS18355	COG3384	dioxygenase
JOA57_RS18360	COG0583	DNA-binding transcription factor activity
JOA57_RS18370	COG0667	Aldo Keto reductase
JOA57_RS18380	COG3590	peptidase
JOA57_RS18395	COG0531	amino acid
JOA57_RS18410	COG2972	Histidine kinase
JOA57_RS18435	COG1335	isochorismatase
JOA57_RS18440	COG3685	Protein conserved in bacteria
JOA57_RS18445	COG3685	Protein conserved in bacteria
JOA57_RS18450	COG3546	catalase activity
JOA57_RS18480	COG2204	response regulator
JOA57_RS18490	COG1271	oxidase subunit
JOA57_RS18495	COG1294	oxidase, subunit
JOA57_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS18535	COG1132	(ABC) transporter
JOA57_RS18550	COG1063	alcohol dehydrogenase
JOA57_RS18590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_RS18650	COG0251	oxidation-reduction process
JOA57_RS18670	COG0667	Aldo Keto reductase
JOA57_RS18675	COG0583	DNA-binding transcription factor activity
JOA57_RS18695	COG4251	negative regulation of phosphorylation
JOA57_RS18695	COG3706	GGDEF domain
JOA57_RS18695	COG2203	Gaf domain
JOA57_RS18695	COG5001	Diguanylate cyclase
JOA57_RS18720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOA57_RS18730	COG1560	Kdo2-lipid A biosynthetic process
JOA57_RS18740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOA57_RS18775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOA57_RS18775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOA57_RS18785	COG0242	peptide deformylase activity
JOA57_RS18790	COG1652	LysM domain
JOA57_RS18795	COG0758	DNA mediated transformation
JOA57_RS18815	COG1754	DNA topoisomerase type I activity
JOA57_RS18815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOA57_RS18835	COG4251	negative regulation of phosphorylation
JOA57_RS18835	COG5001	Diguanylate cyclase
JOA57_RS18835	COG2203	Gaf domain
JOA57_RS18835	COG3706	GGDEF domain
JOA57_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS18850	COG0616	signal peptide processing
JOA57_RS18855	COG0534	Mate efflux family protein
JOA57_RS18870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOA57_RS18875	COG0625	glutathione transferase activity
JOA57_RS18890	COG1252	NADH dehydrogenase
JOA57_RS18895	COG2860	membrane
JOA57_RS18900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOA57_RS18910	COG2201	protein-glutamate methylesterase activity
JOA57_RS18915	COG2177	Part of the ABC transporter FtsEX involved in
JOA57_RS18920	COG2884	Cell division ATP-binding protein ftsE
JOA57_RS18930	COG3118	belongs to the thioredoxin family
JOA57_RS18935	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOA57_RS18980	COG1473	amidohydrolase
JOA57_RS18985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_RS19015	COG4941	Belongs to the sigma-70 factor family
JOA57_RS19020	COG5383	Protein conserved in bacteria
JOA57_RS19055	COG3039	Transposase
JOA57_RS19065	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JOA57_RS19070	COG3409	Peptidoglycan-binding domain 1 protein
JOA57_RS19080	COG3501	Rhs element vgr protein
JOA57_RS19080	COG3409	Peptidoglycan-binding domain 1 protein
JOA57_RS19095	COG3023	N-Acetylmuramoyl-L-alanine amidase
JOA57_RS19105	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_RS19115	COG0531	amino acid
JOA57_RS19130	COG4682	membrane
JOA57_RS19135	COG2133	pyrroloquinoline quinone binding
JOA57_RS19145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOA57_RS19160	COG1610	YqeY-like protein
JOA57_RS19165	COG1295	ribonuclease BN
JOA57_RS19170	COG0358	DNA primase activity
JOA57_RS19220	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JOA57_RS19235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JOA57_RS19280	COG0739	heme binding
JOA57_RS19300	COG0708	Exodeoxyribonuclease III
JOA57_RS19320	COG1192	Involved in chromosome partitioning
JOA57_RS19325	COG1475	DNA binding
JOA57_RS19345	COG0463	Glycosyl transferase, family 2
JOA57_RS19370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOA57_RS19395	COG4221	oxidoreductase activity
JOA57_RS19400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JOA57_RS19400	COG2755	lipolytic protein G-D-S-L family
JOA57_RS19415	COG1166	arginine decarboxylase activity
JOA57_RS19440	COG2960	long-chain fatty acid transporting porin activity
JOA57_RS19445	COG0606	chelatase, subunit chli
JOA57_RS19460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JOA57_RS19545	COG1090	epimerase
JOA57_RS19550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_RS19565	COG0642	Histidine kinase
JOA57_RS19585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOA57_RS19610	COG1011	Hydrolase
JOA57_RS19615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOA57_RS19635	COG2197	response regulator
JOA57_RS19640	COG4585	Histidine kinase
JOA57_RS19655	COG1136	(ABC) transporter
JOA57_RS19680	COG0697	spore germination
JOA57_RS19720	COG0180	Tryptophanyl-tRNA synthetase
JOA57_RS19725	COG3237	CsbD-like
JOA57_RS19800	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JOA57_RS19800	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JOA57_RS19810	COG3228	Belongs to the MtfA family
JOA57_RS19840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOA57_RS19870	COG1199	ATP-dependent helicase activity
JOA57_RS19935	COG0625	glutathione transferase activity
JOA57_RS19970	COG4555	ABC transporter
JOA57_RS19980	COG1476	TRANSCRIPTIONal
JOA57_RS19995	COG1230	cation diffusion facilitator family transporter
JOA57_RS20010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOA57_RS20015	COG1131	(ABC) transporter
JOA57_RS20020	COG0842	Transport permease protein
JOA57_RS20030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOA57_RS20045	COG1607	acyl-coa hydrolase
JOA57_RS20060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOA57_RS20065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOA57_RS20075	COG0045	succinate-CoA ligase (ADP-forming) activity
JOA57_RS20075	COG1042	CoA-binding domain protein
JOA57_RS20075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOA57_RS20080	COG2239	Acts as a magnesium transporter
JOA57_RS20095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOA57_RS20100	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_RS20115	COG3100	YcgL domain-containing protein
JOA57_RS20120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JOA57_RS20130	COG0463	Glycosyl transferase, family 2
JOA57_RS20150	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS20195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOA57_RS20265	COG0210	DNA helicase
JOA57_RS20275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS20280	COG0583	DNA-binding transcription factor activity
JOA57_RS20285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JOA57_RS20295	COG2159	amidohydrolase
JOA57_RS20350	COG2091	lysine biosynthetic process via aminoadipic acid
JOA57_RS20400	COG1940	carbohydrate kinase activity
JOA57_RS20410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JOA57_RS20425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOA57_RS20430	COG3162	membrane
JOA57_RS20465	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_RS20485	COG0179	Fumarylacetoacetate (FAA) hydrolase
JOA57_RS20490	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_RS20495	COG3254	rhamnose metabolic process
JOA57_RS20500	COG0738	Major facilitator superfamily
JOA57_RS20505	COG1414	Transcriptional regulator
JOA57_RS20525	COG2205	protein histidine kinase activity
JOA57_RS20525	COG0784	Response regulator, receiver
JOA57_RS20530	COG3459	Glycosyltransferase 36 associated
JOA57_RS20535	COG2211	Major facilitator Superfamily
JOA57_RS20540	COG3265	gluconokinase activity
JOA57_RS20545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_RS20565	COG2911	Protein conserved in bacteria
JOA57_RS20570	COG0729	surface antigen
JOA57_RS20585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOA57_RS20590	COG0519	Catalyzes the synthesis of GMP from XMP
JOA57_RS20590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JOA57_RS20600	COG0805	protein transport
JOA57_RS20620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JOA57_RS20655	COG3661	Belongs to the glycosyl hydrolase 67 family
JOA57_RS20665	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_RS20675	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_RS20680	COG0246	Mannitol dehydrogenase
JOA57_RS20720	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_RS20735	COG3250	beta-galactosidase activity
JOA57_RS20745	COG3693	PFAM glycoside hydrolase, family 10
JOA57_RS20760	COG2211	Major facilitator Superfamily
JOA57_RS20795	COG2937	Belongs to the GPAT DAPAT family
JOA57_RS20830	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JOA57_RS20850	COG0210	DNA helicase
JOA57_RS20880	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JOA57_RS20930	COG3135	benzoate transporter
JOA57_RS20955	COG0676	glucose-6-phosphate 1-epimerase activity
JOA57_RS20975	COG0730	response to heat
JOA57_RS21005	COG0302	gtp cyclohydrolase
JOA57_RS21020	COG1566	PFAM secretion protein HlyD family protein
JOA57_RS21030	COG1289	transmembrane transporter activity
JOA57_RS21035	COG0477	Major facilitator Superfamily
JOA57_RS21045	COG0583	DNA-binding transcription factor activity
JOA57_RS21050	COG4221	oxidoreductase activity
JOA57_RS21055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_RS21125	COG0564	pseudouridine synthase activity
JOA57_RS21175	COG1074	ATP-dependent DNA helicase activity
JOA57_RS21180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JOA57_RS21215	COG1127	ABC transporter
JOA57_RS21220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JOA57_RS21225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JOA57_RS21240	COG2853	Lipoprotein
JOA57_RS21245	COG0386	Belongs to the glutathione peroxidase family
JOA57_RS21255	COG1322	Protein conserved in bacteria
JOA57_RS21265	COG0604	alcohol dehydrogenase
JOA57_RS21270	COG0583	DNA-binding transcription factor activity
JOA57_RS21285	COG0531	amino acid
JOA57_RS21295	COG4206	TonB-dependent receptor
JOA57_RS21305	COG3706	GGDEF domain
JOA57_RS21310	COG3835	regulator
JOA57_RS21315	COG1929	Belongs to the glycerate kinase type-1 family
JOA57_RS21320	COG2271	Major facilitator Superfamily
JOA57_RS21345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JOA57_RS21350	COG0861	Integral membrane protein TerC family
JOA57_RS21360	COG0584	glycerophosphoryl diester phosphodiesterase
JOA57_RS21370	COG0671	phosphoesterase, PA-phosphatase related
JOA57_RS21385	COG0726	polysaccharide deacetylase
JOA57_RS21390	COG0706	membrane insertase activity