locus-tag	class	description
AEA00_RS00020	COG0187	DNA topoisomerase II activity
AEA00_RS00030	COG0501	Belongs to the peptidase M48B family
AEA00_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEA00_RS00110	COG0793	Belongs to the peptidase S41A family
AEA00_RS00115	COG4942	peptidase
AEA00_RS00125	COG2234	aminopeptidase activity
AEA00_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA00_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA00_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA00_RS00150	COG1064	alcohol dehydrogenase
AEA00_RS00160	COG0493	'glutamate synthase
AEA00_RS00165	COG0067	glutamate synthase
AEA00_RS00165	COG0070	glutamate synthase
AEA00_RS00165	COG0069	glutamate synthase activity
AEA00_RS00180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEA00_RS00190	COG1741	Belongs to the pirin family
AEA00_RS00195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEA00_RS00215	COG0583	DNA-binding transcription factor activity
AEA00_RS00270	COG1205	dead DEAH box helicase
AEA00_RS00270	COG1111	helicase
AEA00_RS00275	COG3177	Filamentation induced by cAMP protein fic
AEA00_RS00280	COG1272	protein, Hemolysin III
AEA00_RS00300	COG2249	NAD(P)H dehydrogenase (quinone) activity
AEA00_RS00310	COG1733	regulation of RNA biosynthetic process
AEA00_RS00355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AEA00_RS00360	COG3237	CsbD-like
AEA00_RS00405	COG0628	permease
AEA00_RS00410	COG0657	acetylesterase activity
AEA00_RS00420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA00_RS00425	COG0477	Major facilitator Superfamily
AEA00_RS00465	COG0714	Associated with various cellular activities
AEA00_RS00505	COG4772	TonB-dependent receptor
AEA00_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
AEA00_RS00550	COG1755	Isoprenylcysteine carboxyl methyltransferase
AEA00_RS00555	COG4585	Histidine kinase
AEA00_RS00560	COG2197	response regulator
AEA00_RS00585	COG3710	Transcriptional regulator
AEA00_RS00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA00_RS00645	COG0366	Alpha amylase catalytic
AEA00_RS00650	COG0366	Alpha amylase catalytic
AEA00_RS00695	COG2755	lipolytic protein G-D-S-L family
AEA00_RS00705	COG2755	lipolytic protein G-D-S-L family
AEA00_RS00705	COG0657	acetylesterase activity
AEA00_RS00715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AEA00_RS00730	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA00_RS00735	COG1609	Transcriptional regulator
AEA00_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS00755	COG2755	lipolytic protein G-D-S-L family
AEA00_RS00765	COG3186	Phenylalanine-4-hydroxylase
AEA00_RS00770	COG1522	sequence-specific DNA binding
AEA00_RS00780	COG1752	Esterase of the alpha-beta hydrolase superfamily
AEA00_RS00790	COG1119	ATPase activity
AEA00_RS00805	COG0517	IMP dehydrogenase activity
AEA00_RS00805	COG1125	glycine betaine transport
AEA00_RS00820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEA00_RS00825	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AEA00_RS00855	COG0489	protein tyrosine kinase activity
AEA00_RS00860	COG0588	phosphoglycerate mutase activity
AEA00_RS00870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS00895	COG1881	PFAM PEBP family protein
AEA00_RS00910	COG0174	glutamine synthetase
AEA00_RS00915	COG0347	Belongs to the P(II) protein family
AEA00_RS00920	COG0004	ammonium transporteR
AEA00_RS00925	COG3852	Histidine kinase
AEA00_RS00930	COG2204	response regulator
AEA00_RS00940	COG2032	superoxide dismutase activity
AEA00_RS00945	COG2032	superoxide dismutase activity
AEA00_RS00950	COG0346	lactoylglutathione lyase activity
AEA00_RS00960	COG0183	Belongs to the thiolase family
AEA00_RS01000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AEA00_RS01020	COG0028	Belongs to the TPP enzyme family
AEA00_RS01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AEA00_RS01050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA00_RS01055	COG3177	Filamentation induced by cAMP protein fic
AEA00_RS01070	COG0596	Alpha beta hydrolase
AEA00_RS01075	COG0727	PFAM Uncharacterised protein family (UPF0153)
AEA00_RS01085	COG0318	PFAM AMP-dependent synthetase and ligase
AEA00_RS01090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEA00_RS01105	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEA00_RS01120	COG0564	pseudouridine synthase activity
AEA00_RS01140	COG1446	asparaginase
AEA00_RS01145	COG0339	signal peptide processing
AEA00_RS01175	COG0583	DNA-binding transcription factor activity
AEA00_RS01180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AEA00_RS01185	COG2224	Isocitrate lyase
AEA00_RS01215	COG4770	biotin carboxylase activity
AEA00_RS01220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEA00_RS01225	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS01290	COG0697	spore germination
AEA00_RS01300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AEA00_RS01310	COG1846	Transcriptional regulator
AEA00_RS01315	COG1764	response to oxidative stress
AEA00_RS01340	COG0656	L-ascorbic acid biosynthetic process
AEA00_RS01345	COG2130	NADP-dependent
AEA00_RS01360	COG1187	pseudouridine synthase activity
AEA00_RS01370	COG1643	Atp-dependent helicase
AEA00_RS01375	COG0840	transmembrane signaling receptor activity
AEA00_RS01380	COG4807	Protein conserved in bacteria
AEA00_RS01385	COG2351	hydroxyisourate hydrolase activity
AEA00_RS01390	COG2072	flavoprotein involved in K transport
AEA00_RS01410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AEA00_RS01445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS01460	COG1957	nucleoside hydrolase
AEA00_RS01470	COG2252	PERMEase
AEA00_RS01490	COG0084	hydrolase, TatD family'
AEA00_RS01500	COG0583	DNA-binding transcription factor activity
AEA00_RS01505	COG2814	Major facilitator Superfamily
AEA00_RS01530	COG1902	pentaerythritol trinitrate reductase activity
AEA00_RS01555	COG0300	oxidoreductase activity
AEA00_RS01565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEA00_RS01570	COG0583	DNA-binding transcription factor activity
AEA00_RS01600	COG0702	epimerase
AEA00_RS01605	COG1733	regulation of RNA biosynthetic process
AEA00_RS01615	COG0840	transmembrane signaling receptor activity
AEA00_RS01740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AEA00_RS01795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AEA00_RS01820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEA00_RS01825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEA00_RS01835	COG3485	protocatechuate 3,4-dioxygenase
AEA00_RS01840	COG3485	protocatechuate 3,4-dioxygenase
AEA00_RS01850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA00_RS01855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AEA00_RS01865	COG1414	Transcriptional regulator
AEA00_RS01875	COG0657	acetylesterase activity
AEA00_RS01895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEA00_RS01945	COG1040	competence protein
AEA00_RS01960	COG0582	viral genome integration into host DNA
AEA00_RS01970	COG4774	siderophore transport
AEA00_RS01980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEA00_RS01995	COG4206	TonB-dependent receptor
AEA00_RS02010	COG2963	transposase activity
AEA00_RS02015	COG2801	Transposase and inactivated derivatives
AEA00_RS02025	COG3264	Mechanosensitive ion channel
AEA00_RS02025	COG1511	domain protein
AEA00_RS02030	COG1368	sulfuric ester hydrolase activity
AEA00_RS02035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEA00_RS02040	COG2354	Protein conserved in bacteria
AEA00_RS02045	COG1649	PFAM Uncharacterised BCR, COG1649
AEA00_RS02055	COG0297	glycogen (starch) synthase activity
AEA00_RS02065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEA00_RS02090	COG0702	epimerase
AEA00_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS02130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA00_RS02140	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEA00_RS02155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEA00_RS02170	COG3104	oligopeptide transport
AEA00_RS02190	COG2852	Protein conserved in bacteria
AEA00_RS02215	COG1320	monovalent cation:proton antiporter activity
AEA00_RS02220	COG2212	antiporter activity
AEA00_RS02230	COG0651	ATP synthesis coupled electron transport
AEA00_RS02235	COG1006	Multisubunit Na H antiporter MnhC subunit
AEA00_RS02240	COG2111	Na H antiporter
AEA00_RS02240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEA00_RS02310	COG0436	Aminotransferase
AEA00_RS02330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEA00_RS02435	COG2816	NAD+ diphosphatase activity
AEA00_RS02440	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AEA00_RS02465	COG2814	Major facilitator Superfamily
AEA00_RS02470	COG1289	transmembrane transporter activity
AEA00_RS02475	COG0151	Belongs to the GarS family
AEA00_RS02485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEA00_RS02490	COG2267	carboxylic ester hydrolase activity
AEA00_RS02495	COG2453	phosphatase
AEA00_RS02495	COG0671	phosphoesterase, PA-phosphatase related
AEA00_RS02520	COG4589	Belongs to the CDS family
AEA00_RS02530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AEA00_RS02565	COG0439	Biotin carboxylase
AEA00_RS02575	COG0511	ligase activity, forming carbon-carbon bonds
AEA00_RS02590	COG1324	tolerance protein
AEA00_RS02595	COG2356	endonuclease I
AEA00_RS02610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEA00_RS02650	COG2963	transposase activity
AEA00_RS02660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AEA00_RS02685	COG3386	PFAM SMP-30 Gluconolaconase
AEA00_RS02700	COG3712	iron ion homeostasis
AEA00_RS02735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AEA00_RS02760	COG2353	YceI-like domain
AEA00_RS02815	COG1802	Transcriptional regulator
AEA00_RS02895	COG0435	Glutathione S-transferase
AEA00_RS02955	COG2409	Drug exporters of the RND superfamily
AEA00_RS02965	COG0823	Involved in the tonB-independent uptake of proteins
AEA00_RS02965	COG1506	peptidase
AEA00_RS02980	COG1959	2 iron, 2 sulfur cluster binding
AEA00_RS03020	COG0697	spore germination
AEA00_RS03035	COG4305	rare lipoprotein A
AEA00_RS03040	COG5297	Belongs to the glycosyl hydrolase family 6
AEA00_RS03045	COG1113	amino acid transport
AEA00_RS03095	COG5001	Diguanylate cyclase
AEA00_RS03095	COG5002	protein histidine kinase activity
AEA00_RS03095	COG3447	MASE1 domain protein
AEA00_RS03100	COG0840	transmembrane signaling receptor activity
AEA00_RS03105	COG5297	Belongs to the glycosyl hydrolase family 6
AEA00_RS03105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA00_RS03110	COG0659	secondary active sulfate transmembrane transporter activity
AEA00_RS03115	COG3706	GGDEF domain
AEA00_RS03130	COG3273	potassium ion transport
AEA00_RS03130	COG0471	metal ion transport
AEA00_RS03145	COG3275	phosphorelay sensor kinase activity
AEA00_RS03180	COG1505	serine-type exopeptidase activity
AEA00_RS03195	COG0436	Aminotransferase
AEA00_RS03205	COG2832	Protein of unknown function (DUF454)
AEA00_RS03235	COG2963	transposase activity
AEA00_RS03275	COG2226	methyltransferase
AEA00_RS03280	COG5001	Diguanylate cyclase
AEA00_RS03280	COG3300	MHYT domain
AEA00_RS03285	COG0308	aminopeptidase N
AEA00_RS03305	COG2963	transposase activity
AEA00_RS03335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AEA00_RS03350	COG3284	Transcriptional regulator
AEA00_RS03355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA00_RS03360	COG1077	Cell shape determining protein MreB Mrl
AEA00_RS03365	COG1792	Involved in formation and maintenance of cell shape
AEA00_RS03380	COG0772	Belongs to the SEDS family
AEA00_RS03390	COG2963	transposase activity
AEA00_RS03395	COG2801	Transposase and inactivated derivatives
AEA00_RS03435	COG2951	lytic endotransglycosylase activity
AEA00_RS03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEA00_RS03445	COG1686	Belongs to the peptidase S11 family
AEA00_RS03495	COG1056	cytidyltransferase-related domain
AEA00_RS03495	COG1051	belongs to the nudix hydrolase family
AEA00_RS03530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AEA00_RS03535	COG0673	inositol 2-dehydrogenase activity
AEA00_RS03540	COG2823	Periplasmic or secreted lipoprotein
AEA00_RS03545	COG4251	negative regulation of phosphorylation
AEA00_RS03550	COG0784	Response regulator, receiver
AEA00_RS03555	COG4191	Histidine kinase
AEA00_RS03560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AEA00_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS03610	COG1459	type II secretion system
AEA00_RS03625	COG2165	general secretion pathway protein
AEA00_RS03630	COG4795	General secretion pathway protein
AEA00_RS03655	COG2188	Transcriptional regulator
AEA00_RS03665	COG1609	Transcriptional regulator
AEA00_RS03670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEA00_RS03675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AEA00_RS03715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AEA00_RS03725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEA00_RS03750	COG2205	protein histidine kinase activity
AEA00_RS03775	COG0583	DNA-binding transcription factor activity
AEA00_RS03795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AEA00_RS03800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEA00_RS03810	COG0697	spore germination
AEA00_RS03820	COG1307	EDD domain protein, DegV family
AEA00_RS03860	COG0402	S-adenosylhomocysteine deaminase activity
AEA00_RS03880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEA00_RS03900	COG0436	Aminotransferase
AEA00_RS03935	COG2211	Major facilitator Superfamily
AEA00_RS03940	COG1609	Transcriptional regulator
AEA00_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS03950	COG2851	Citrate transporter
AEA00_RS03965	COG0642	Histidine kinase
AEA00_RS03980	COG2197	response regulator
AEA00_RS03990	COG4191	Histidine kinase
AEA00_RS04030	COG1560	Kdo2-lipid A biosynthetic process
AEA00_RS04035	COG1519	Transferase
AEA00_RS04040	COG1538	Outer membrane efflux protein
AEA00_RS04045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEA00_RS04055	COG5001	Diguanylate cyclase
AEA00_RS04055	COG3300	MHYT domain
AEA00_RS04065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEA00_RS04075	COG2226	methyltransferase
AEA00_RS04110	COG0405	Gamma-glutamyltransferase
AEA00_RS04115	COG0840	transmembrane signaling receptor activity
AEA00_RS04120	COG4946	Tricorn protease homolog
AEA00_RS04120	COG1506	peptidase
AEA00_RS04120	COG0823	Involved in the tonB-independent uptake of proteins
AEA00_RS04135	COG3710	Transcriptional regulator
AEA00_RS04155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEA00_RS04165	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEA00_RS04200	COG2963	transposase activity
AEA00_RS04265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEA00_RS04275	COG3781	membrane
AEA00_RS04280	COG0671	phosphoesterase, PA-phosphatase related
AEA00_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS04300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEA00_RS04305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEA00_RS04335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEA00_RS04365	COG1773	rubredoxin
AEA00_RS04370	COG2912	Transglutaminase-like superfamily
AEA00_RS04390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEA00_RS04410	COG0006	proline dipeptidase activity
AEA00_RS04420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEA00_RS04420	COG3453	Protein conserved in bacteria
AEA00_RS04435	COG0725	ABC transporter, periplasmic molybdate-binding protein
AEA00_RS04440	COG4149	molybdate abc transporter
AEA00_RS04485	COG1376	ErfK ybiS ycfS ynhG family protein
AEA00_RS04490	COG0739	heme binding
AEA00_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS04505	COG2801	Transposase and inactivated derivatives
AEA00_RS04510	COG0596	Alpha beta hydrolase
AEA00_RS04515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AEA00_RS04520	COG1301	dicarboxylic acid transport
AEA00_RS04530	COG2304	oxidoreductase activity
AEA00_RS04550	COG0714	Associated with various cellular activities
AEA00_RS04580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEA00_RS04605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEA00_RS04615	COG2721	sulfolactate sulfo-lyase activity
AEA00_RS04630	COG2271	Major facilitator Superfamily
AEA00_RS04645	COG0583	DNA-binding transcription factor activity
AEA00_RS04650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEA00_RS04665	COG1561	YicC-like family, N-terminal region
AEA00_RS04675	COG0346	lactoylglutathione lyase activity
AEA00_RS04685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEA00_RS04710	COG3047	cAMP biosynthetic process
AEA00_RS04725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEA00_RS04755	COG0469	pyruvate kinase activity
AEA00_RS04760	COG3588	fructose-bisphosphate aldolase
AEA00_RS04765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AEA00_RS04795	COG2198	Histidine kinase
AEA00_RS04795	COG2205	protein histidine kinase activity
AEA00_RS04795	COG0784	Response regulator, receiver
AEA00_RS04825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AEA00_RS04835	COG2895	sulfate adenylyltransferase (ATP) activity
AEA00_RS04835	COG0529	Catalyzes the synthesis of activated sulfate
AEA00_RS04845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA00_RS04850	COG0308	aminopeptidase N
AEA00_RS04860	COG1115	amino acid carrier protein
AEA00_RS04865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEA00_RS04870	COG2272	Belongs to the type-B carboxylesterase lipase family
AEA00_RS04875	COG4948	Mandelate Racemase Muconate Lactonizing
AEA00_RS04880	COG3250	beta-galactosidase activity
AEA00_RS04890	COG5297	Belongs to the glycosyl hydrolase family 6
AEA00_RS04895	COG1609	Transcriptional regulator
AEA00_RS04930	COG0471	metal ion transport
AEA00_RS04930	COG3273	potassium ion transport
AEA00_RS04960	COG0582	viral genome integration into host DNA
AEA00_RS04980	COG1396	sequence-specific DNA binding
AEA00_RS04985	COG0583	DNA-binding transcription factor activity
AEA00_RS05000	COG2801	Transposase and inactivated derivatives
AEA00_RS05005	COG2963	transposase activity
AEA00_RS05030	COG2963	transposase activity
AEA00_RS05040	COG2801	Transposase and inactivated derivatives
AEA00_RS05045	COG2963	transposase activity
AEA00_RS05060	COG5001	Diguanylate cyclase
AEA00_RS05135	COG0745	RESPONSE REGULATOR receiver
AEA00_RS05170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AEA00_RS05175	COG1459	type II secretion system
AEA00_RS05225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEA00_RS05225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEA00_RS05235	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_RS05240	COG0564	pseudouridine synthase activity
AEA00_RS05260	COG0840	transmembrane signaling receptor activity
AEA00_RS05275	COG3387	PFAM Glycoside hydrolase 15-related
AEA00_RS05280	COG1877	trehalose-phosphatase activity
AEA00_RS05325	COG1116	anion transmembrane transporter activity
AEA00_RS05330	COG0542	response to heat
AEA00_RS05345	COG4206	TonB-dependent receptor
AEA00_RS05365	COG1797	cobyrinic acid a,c-diamide synthase activity
AEA00_RS05370	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AEA00_RS05410	COG0019	diaminopimelate decarboxylase activity
AEA00_RS05415	COG4264	IucA IucC family
AEA00_RS05420	COG2814	Major facilitator Superfamily
AEA00_RS05425	COG4264	IucA IucC family
AEA00_RS05435	COG4772	TonB-dependent receptor
AEA00_RS05445	COG4651	solute:proton antiporter activity
AEA00_RS05445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEA00_RS05475	COG0488	(ABC) transporter
AEA00_RS05495	COG0657	acetylesterase activity
AEA00_RS05495	COG2755	lipolytic protein G-D-S-L family
AEA00_RS05515	COG0477	Major facilitator Superfamily
AEA00_RS05580	COG0824	Thioesterase
AEA00_RS05590	COG0848	biopolymer transport protein
AEA00_RS05605	COG2885	chlorophyll binding
AEA00_RS05615	COG0602	queuosine metabolic process
AEA00_RS05660	COG0583	DNA-binding transcription factor activity
AEA00_RS05685	COG1187	pseudouridine synthase activity
AEA00_RS05705	COG0514	ATP-dependent DNA helicase (RecQ)
AEA00_RS05710	COG0783	Belongs to the Dps family
AEA00_RS05715	COG1643	Atp-dependent helicase
AEA00_RS05760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEA00_RS05770	COG1215	transferase activity, transferring glycosyl groups
AEA00_RS05775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEA00_RS05785	COG1199	ATP-dependent helicase activity
AEA00_RS05795	COG1397	ADP-ribosylglycohydrolase
AEA00_RS05805	COG0189	ligase activity
AEA00_RS05820	COG0835	chemotaxis
AEA00_RS05825	COG0840	transmembrane signaling receptor activity
AEA00_RS05830	COG0784	Response regulator, receiver
AEA00_RS05830	COG0643	Histidine kinase
AEA00_RS05830	COG2198	Histidine kinase
AEA00_RS05855	COG1595	DNA-templated transcription, initiation
AEA00_RS05860	COG2304	oxidoreductase activity
AEA00_RS05865	COG1446	asparaginase
AEA00_RS05910	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEA00_RS05920	COG3645	SOS response
AEA00_RS05945	COG2963	transposase activity
AEA00_RS05965	COG3537	Alpha-1,2-mannosidase
AEA00_RS05975	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA00_RS05985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AEA00_RS05990	COG3858	chitin binding
AEA00_RS05990	COG1388	LysM domain
AEA00_RS06005	COG0837	glucose binding
AEA00_RS06010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEA00_RS06020	COG0494	nUDIX hydrolase
AEA00_RS06025	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEA00_RS06030	COG3956	TIGRFAM MazG family protein
AEA00_RS06040	COG0330	HflC and HflK could
AEA00_RS06080	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS06090	COG1309	transcriptional regulator
AEA00_RS06105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AEA00_RS06115	COG0463	Glycosyl transferase, family 2
AEA00_RS06120	COG0517	IMP dehydrogenase activity
AEA00_RS06120	COG0516	GMP reductase activity
AEA00_RS06125	COG2982	Protein involved in outer membrane biogenesis
AEA00_RS06130	COG1272	protein, Hemolysin III
AEA00_RS06145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA00_RS06150	COG0626	cystathionine gamma-synthase activity
AEA00_RS06155	COG0527	aspartate kinase activity
AEA00_RS06155	COG0460	homoserine dehydrogenase
AEA00_RS06165	COG1760	l-serine dehydratase
AEA00_RS06185	COG2353	YceI-like domain
AEA00_RS06205	COG0477	Major facilitator Superfamily
AEA00_RS06240	COG1842	Phage shock protein A
AEA00_RS06265	COG0754	glutathionylspermidine amidase activity
AEA00_RS06270	COG2814	Major facilitator Superfamily
AEA00_RS06350	COG0531	amino acid
AEA00_RS06355	COG2197	response regulator
AEA00_RS06370	COG1113	amino acid transport
AEA00_RS06375	COG1271	oxidase subunit
AEA00_RS06380	COG1294	oxidase, subunit
AEA00_RS06390	COG2239	Acts as a magnesium transporter
AEA00_RS06395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEA00_RS06400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA00_RS06420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA00_RS06435	COG1137	ATPase activity
AEA00_RS06450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AEA00_RS06460	COG0271	Belongs to the BolA IbaG family
AEA00_RS06485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEA00_RS06505	COG0628	permease
AEA00_RS06515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEA00_RS06530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEA00_RS06535	COG1555	photosystem II stabilization
AEA00_RS06580	COG4774	siderophore transport
AEA00_RS06595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEA00_RS06600	COG0719	Fe-S assembly protein
AEA00_RS06605	COG0396	ATPase activity
AEA00_RS06610	COG0719	Fe-S assembly protein
AEA00_RS06625	COG0693	protein deglycase activity
AEA00_RS06660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEA00_RS06690	COG0519	Catalyzes the synthesis of GMP from XMP
AEA00_RS06695	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AEA00_RS06715	COG1764	response to oxidative stress
AEA00_RS06725	COG0384	phenazine biosynthesis protein PhzF
AEA00_RS06730	COG0384	phenazine biosynthesis protein PhzF
AEA00_RS06735	COG0527	aspartate kinase activity
AEA00_RS06760	COG0142	geranyltranstransferase activity
AEA00_RS06765	COG0629	single-stranded DNA binding
AEA00_RS06775	COG1401	restriction endodeoxyribonuclease activity
AEA00_RS06785	COG5001	Diguanylate cyclase
AEA00_RS06785	COG3706	GGDEF domain
AEA00_RS06785	COG4251	negative regulation of phosphorylation
AEA00_RS06785	COG2203	Gaf domain
AEA00_RS06790	COG0604	alcohol dehydrogenase
AEA00_RS06795	COG2080	2 iron, 2 sulfur cluster binding
AEA00_RS06800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEA00_RS06805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA00_RS06810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AEA00_RS06815	COG0746	molybdenum cofactor guanylyltransferase activity
AEA00_RS06845	COG2879	small protein
AEA00_RS06850	COG1966	Carbon starvation protein
AEA00_RS06855	COG1741	Belongs to the pirin family
AEA00_RS06870	COG1741	Belongs to the pirin family
AEA00_RS06890	COG3590	peptidase
AEA00_RS06895	COG3039	Transposase
AEA00_RS06900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS06910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEA00_RS06915	COG2199	diguanylate cyclase activity
AEA00_RS06915	COG2200	EAL domain
AEA00_RS06915	COG2202	Pas domain
AEA00_RS06920	COG0835	chemotaxis
AEA00_RS06925	COG0840	transmembrane signaling receptor activity
AEA00_RS06930	COG0643	Histidine kinase
AEA00_RS06930	COG2198	Histidine kinase
AEA00_RS06940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEA00_RS06950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AEA00_RS06955	COG0745	RESPONSE REGULATOR receiver
AEA00_RS06960	COG2205	protein histidine kinase activity
AEA00_RS06970	COG4452	Inner membrane protein CreD
AEA00_RS07005	COG0735	belongs to the Fur family
AEA00_RS07020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA00_RS07030	COG1309	transcriptional regulator
AEA00_RS07035	COG0667	Aldo Keto reductase
AEA00_RS07050	COG2207	Transcriptional regulator
AEA00_RS07070	COG0583	DNA-binding transcription factor activity
AEA00_RS07075	COG2814	Major facilitator Superfamily
AEA00_RS07105	COG3383	formate dehydrogenase (NAD+) activity
AEA00_RS07115	COG1271	oxidase subunit
AEA00_RS07120	COG1294	oxidase, subunit
AEA00_RS07225	COG5002	protein histidine kinase activity
AEA00_RS07225	COG5001	Diguanylate cyclase
AEA00_RS07230	COG1187	pseudouridine synthase activity
AEA00_RS07265	COG0475	glutathione-regulated potassium exporter activity
AEA00_RS07270	COG1132	(ABC) transporter
AEA00_RS07315	COG2155	Conserved Protein
AEA00_RS07325	COG3118	belongs to the thioredoxin family
AEA00_RS07350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEA00_RS07375	COG2968	Membrane
AEA00_RS07390	COG3164	Protein of unknown function
AEA00_RS07400	COG0312	modulator of DNA gyrase
AEA00_RS07410	COG0312	modulator of DNA gyrase
AEA00_RS07425	COG0142	geranyltranstransferase activity
AEA00_RS07440	COG1785	Belongs to the alkaline phosphatase family
AEA00_RS07445	COG1301	dicarboxylic acid transport
AEA00_RS07450	COG4106	trans-aconitate 2-methyltransferase activity
AEA00_RS07475	COG4191	Histidine kinase
AEA00_RS07480	COG3284	Transcriptional regulator
AEA00_RS07515	COG0791	NLP P60 protein
AEA00_RS07520	COG0791	NLP P60 protein
AEA00_RS07525	COG1047	Peptidyl-prolyl cis-trans
AEA00_RS07530	COG2311	Membrane
AEA00_RS07535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA00_RS07540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEA00_RS07560	COG3590	peptidase
AEA00_RS07565	COG3590	peptidase
AEA00_RS07580	COG0489	protein tyrosine kinase activity
AEA00_RS07605	COG0412	Dienelactone hydrolase
AEA00_RS07620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA00_RS07635	COG0494	nUDIX hydrolase
AEA00_RS07640	COG0433	COG0433 Predicted ATPase
AEA00_RS07665	COG2890	protein-(glutamine-N5) methyltransferase activity
AEA00_RS07680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEA00_RS07685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEA00_RS07770	COG4221	oxidoreductase activity
AEA00_RS07790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEA00_RS07810	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AEA00_RS07815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA00_RS07835	COG0839	Belongs to the complex I subunit 6 family
AEA00_RS07855	COG1007	ATP synthesis coupled electron transport
AEA00_RS07870	COG0195	Participates in both transcription termination and antitermination
AEA00_RS07930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEA00_RS07940	COG2095	MarC family integral membrane protein
AEA00_RS07950	COG1611	Belongs to the LOG family
AEA00_RS07955	COG4969	Belongs to the N-Me-Phe pilin family
AEA00_RS08005	COG3505	Type IV secretory pathway VirD4
AEA00_RS08025	COG2948	multi-organism process
AEA00_RS08045	COG3702	type iv secretory pathway
AEA00_RS08065	COG0366	Alpha amylase catalytic
AEA00_RS08070	COG3039	Transposase
AEA00_RS08080	COG1082	Xylose isomerase domain protein TIM barrel
AEA00_RS08110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEA00_RS08180	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS08185	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS08190	COG2244	polysaccharide biosynthetic process
AEA00_RS08195	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS08220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA00_RS08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEA00_RS08230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEA00_RS08260	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS08285	COG0322	excinuclease ABC activity
AEA00_RS08310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEA00_RS08320	COG4191	Histidine kinase
AEA00_RS08320	COG0784	Response regulator, receiver
AEA00_RS08340	COG0552	protein localization to endoplasmic reticulum
AEA00_RS08350	COG3938	Belongs to the proline racemase family
AEA00_RS08370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEA00_RS08380	COG0006	proline dipeptidase activity
AEA00_RS08395	COG0531	amino acid
AEA00_RS08425	COG4206	TonB-dependent receptor
AEA00_RS08435	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA00_RS08440	COG1506	peptidase
AEA00_RS08440	COG0823	Involved in the tonB-independent uptake of proteins
AEA00_RS08450	COG4206	TonB-dependent receptor
AEA00_RS08465	COG0326	Molecular chaperone. Has ATPase activity
AEA00_RS08470	COG0742	ribosomal rna small subunit methyltransferase
AEA00_RS08490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEA00_RS08495	COG0405	Gamma-glutamyltransferase
AEA00_RS08500	COG3291	Pkd domain containing protein
AEA00_RS08530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AEA00_RS08550	COG1862	Preprotein translocase
AEA00_RS08560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEA00_RS08580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEA00_RS08580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEA00_RS08585	COG1105	Belongs to the carbohydrate kinase PfkB family
AEA00_RS08590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA00_RS08590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEA00_RS08595	COG1609	Transcriptional regulator
AEA00_RS08600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA00_RS08605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA00_RS08615	COG2902	Dehydrogenase
AEA00_RS08620	COG2207	Transcriptional regulator
AEA00_RS08620	COG1609	Transcriptional regulator
AEA00_RS08625	COG1335	isochorismatase
AEA00_RS08630	COG0477	Major facilitator Superfamily
AEA00_RS08645	COG2733	membrane
AEA00_RS08655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AEA00_RS08660	COG2223	nitrite transmembrane transporter activity
AEA00_RS08670	COG0243	molybdopterin cofactor binding
AEA00_RS08680	COG0477	Major facilitator Superfamily
AEA00_RS08685	COG2703	oxygen carrier activity
AEA00_RS08695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA00_RS08700	COG0174	glutamine synthetase
AEA00_RS08705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AEA00_RS08740	COG3842	ATPase activity
AEA00_RS08745	COG1176	ABC-type spermidine putrescine transport system, permease component I
AEA00_RS08750	COG1177	transmembrane transport
AEA00_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
AEA00_RS08775	COG4535	Mg2 and Co2 transporter CorC
AEA00_RS08795	COG1702	phosphate starvation-inducible protein PhoH
AEA00_RS08815	COG0741	lytic transglycosylase activity
AEA00_RS08820	COG0723	plastoquinol--plastocyanin reductase activity
AEA00_RS08825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AEA00_RS08830	COG2857	Cytochrome c1
AEA00_RS08835	COG0625	glutathione transferase activity
AEA00_RS08840	COG2969	positive regulation of protein catabolic process
AEA00_RS08855	COG1201	RNA secondary structure unwinding
AEA00_RS08865	COG0840	transmembrane signaling receptor activity
AEA00_RS08870	COG0835	chemotaxis
AEA00_RS08920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEA00_RS08935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEA00_RS08940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEA00_RS08940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEA00_RS08950	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEA00_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS08990	COG5001	Diguanylate cyclase
AEA00_RS08990	COG3300	MHYT domain
AEA00_RS08995	COG2081	HI0933 family
AEA00_RS09000	COG4681	YaeQ
AEA00_RS09035	COG0513	Belongs to the DEAD box helicase family
AEA00_RS09040	COG0488	(ABC) transporter
AEA00_RS09055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEA00_RS09060	COG0483	inositol monophosphate 1-phosphatase activity
AEA00_RS09075	COG5001	Diguanylate cyclase
AEA00_RS09075	COG3300	MHYT domain
AEA00_RS09080	COG1509	lysine 2,3-aminomutase activity
AEA00_RS09095	COG0402	S-adenosylhomocysteine deaminase activity
AEA00_RS09120	COG4677	pectinesterase activity
AEA00_RS09140	COG4302	ethanolamine ammonia-lyase activity
AEA00_RS09160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEA00_RS09195	COG2166	iron-sulfur cluster assembly
AEA00_RS09210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEA00_RS09220	COG0137	argininosuccinate synthase activity
AEA00_RS09225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEA00_RS09230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEA00_RS09290	COG1294	oxidase, subunit
AEA00_RS09300	COG4988	ABC transporter
AEA00_RS09305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AEA00_RS09365	COG0436	Aminotransferase
AEA00_RS09385	COG1187	pseudouridine synthase activity
AEA00_RS09390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEA00_RS09395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AEA00_RS09400	COG2350	Protein conserved in bacteria
AEA00_RS09425	COG2182	Extracellular solute-binding protein
AEA00_RS09435	COG0395	ABC-type sugar transport system, permease component
AEA00_RS09460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEA00_RS09465	COG2957	Belongs to the agmatine deiminase family
AEA00_RS09485	COG0539	negative regulation of cytoplasmic translation
AEA00_RS09500	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AEA00_RS09515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AEA00_RS09520	COG0475	glutathione-regulated potassium exporter activity
AEA00_RS09520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEA00_RS09560	COG2197	response regulator
AEA00_RS09575	COG1335	isochorismatase
AEA00_RS09590	COG2814	Major facilitator Superfamily
AEA00_RS09605	COG1914	H( )-stimulated, divalent metal cation uptake system
AEA00_RS09625	COG0668	transmembrane transport
AEA00_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS09655	COG1183	phosphatidylcholine synthase activity
AEA00_RS09665	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEA00_RS09680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA00_RS09680	COG0723	plastoquinol--plastocyanin reductase activity
AEA00_RS09690	COG2183	response to ionizing radiation
AEA00_RS09695	COG5001	Diguanylate cyclase
AEA00_RS09760	COG0800	Aldolase
AEA00_RS09765	COG0129	dihydroxy-acid dehydratase activity
AEA00_RS09770	COG0363	glucosamine-6-phosphate deaminase activity
AEA00_RS09780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEA00_RS09790	COG0354	folic acid binding
AEA00_RS09800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AEA00_RS09805	COG1053	succinate dehydrogenase
AEA00_RS09815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AEA00_RS09830	COG4591	ABC-type transport system involved in lipoprotein release permease component
AEA00_RS09850	COG0811	peptide transport
AEA00_RS09855	COG0848	biopolymer transport protein
AEA00_RS09875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEA00_RS09890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEA00_RS09915	COG2963	transposase activity
AEA00_RS09925	COG3039	Transposase
AEA00_RS09935	COG2963	transposase activity
AEA00_RS09945	COG3039	Transposase
AEA00_RS09990	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEA00_RS10025	COG1530	ribonuclease E activity
AEA00_RS10035	COG0428	transporter
AEA00_RS10125	COG3459	Glycosyltransferase 36 associated
AEA00_RS10135	COG0784	Response regulator, receiver
AEA00_RS10135	COG4191	Histidine kinase
AEA00_RS10165	COG0840	transmembrane signaling receptor activity
AEA00_RS10175	COG1238	metal cluster binding
AEA00_RS10200	COG1733	regulation of RNA biosynthetic process
AEA00_RS10215	COG1999	signal sequence binding
AEA00_RS10230	COG3590	peptidase
AEA00_RS10300	COG5001	Diguanylate cyclase
AEA00_RS10310	COG2201	protein-glutamate methylesterase activity
AEA00_RS10315	COG3685	Protein conserved in bacteria
AEA00_RS10330	COG0579	oxidoreductase
AEA00_RS10340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEA00_RS10350	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AEA00_RS10370	COG0243	molybdopterin cofactor binding
AEA00_RS10380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AEA00_RS10385	COG2223	nitrite transmembrane transporter activity
AEA00_RS10390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AEA00_RS10400	COG1648	precorrin-2 dehydrogenase activity
AEA00_RS10400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEA00_RS10410	COG0746	molybdenum cofactor guanylyltransferase activity
AEA00_RS10415	COG0303	'Molybdopterin
AEA00_RS10425	COG0708	Exodeoxyribonuclease III
AEA00_RS10450	COG2124	cytochrome p450
AEA00_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS10470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AEA00_RS10485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_RS10520	COG1024	Enoyl-CoA hydratase
AEA00_RS10520	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEA00_RS10525	COG0183	Belongs to the thiolase family
AEA00_RS10530	COG0038	chloride channel
AEA00_RS10535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEA00_RS10555	COG1674	ftsk spoiiie
AEA00_RS10560	COG0492	ferredoxin-NADP+ reductase activity
AEA00_RS10580	COG0542	response to heat
AEA00_RS10600	COG2915	High frequency lysogenization protein hflD homolog
AEA00_RS10635	COG4191	Histidine kinase
AEA00_RS10655	COG0835	chemotaxis
AEA00_RS10655	COG0784	Response regulator, receiver
AEA00_RS10665	COG1558	bacterial-type flagellum-dependent cell motility
AEA00_RS10670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AEA00_RS10680	COG4787	bacterial-type flagellum-dependent cell motility
AEA00_RS10700	COG3951	Flagellar rod assembly protein muramidase FlgJ
AEA00_RS10700	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEA00_RS10710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEA00_RS10715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEA00_RS10720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AEA00_RS10750	COG2201	protein-glutamate methylesterase activity
AEA00_RS10780	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS10780	COG1216	Glycosyl transferase, family 2
AEA00_RS10785	COG1677	Flagellar hook-basal body complex protein FliE
AEA00_RS10850	COG1987	bacterial-type flagellum assembly
AEA00_RS10855	COG1684	flagellar biosynthetic protein fliR
AEA00_RS10915	COG2198	Histidine kinase
AEA00_RS10915	COG0643	Histidine kinase
AEA00_RS10915	COG0784	Response regulator, receiver
AEA00_RS10955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AEA00_RS10975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AEA00_RS10980	COG1360	Flagellar Motor Protein
AEA00_RS10985	COG1192	Involved in chromosome partitioning
AEA00_RS10990	COG0835	chemotaxis
AEA00_RS11000	COG0745	RESPONSE REGULATOR receiver
AEA00_RS11010	COG0840	transmembrane signaling receptor activity
AEA00_RS11020	COG0840	transmembrane signaling receptor activity
AEA00_RS11025	COG0840	transmembrane signaling receptor activity
AEA00_RS11030	COG0840	transmembrane signaling receptor activity
AEA00_RS11035	COG0840	transmembrane signaling receptor activity
AEA00_RS11040	COG0840	transmembrane signaling receptor activity
AEA00_RS11045	COG0840	transmembrane signaling receptor activity
AEA00_RS11050	COG0840	transmembrane signaling receptor activity
AEA00_RS11060	COG0835	chemotaxis
AEA00_RS11070	COG0840	transmembrane signaling receptor activity
AEA00_RS11095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA00_RS11125	COG0318	PFAM AMP-dependent synthetase and ligase
AEA00_RS11130	COG1024	Enoyl-CoA hydratase
AEA00_RS11135	COG2205	protein histidine kinase activity
AEA00_RS11135	COG2198	Histidine kinase
AEA00_RS11135	COG0784	Response regulator, receiver
AEA00_RS11140	COG2198	Histidine kinase
AEA00_RS11140	COG0784	Response regulator, receiver
AEA00_RS11140	COG2205	protein histidine kinase activity
AEA00_RS11155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEA00_RS11160	COG3279	Response regulator of the LytR AlgR family
AEA00_RS11185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEA00_RS11195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA00_RS11200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AEA00_RS11210	COG0505	Belongs to the CarA family
AEA00_RS11220	COG2258	MOSC domain
AEA00_RS11225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEA00_RS11250	COG1024	Enoyl-CoA hydratase
AEA00_RS11285	COG0277	FAD linked oxidase domain protein
AEA00_RS11290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEA00_RS11305	COG0531	amino acid
AEA00_RS11310	COG0531	amino acid
AEA00_RS11340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEA00_RS11340	COG0140	phosphoribosyl-ATP diphosphatase activity
AEA00_RS11360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AEA00_RS11360	COG0131	Imidazoleglycerol-phosphate dehydratase
AEA00_RS11390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEA00_RS11400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AEA00_RS11440	COG2963	transposase activity
AEA00_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
AEA00_RS11490	COG0697	spore germination
AEA00_RS11495	COG1794	racemase activity, acting on amino acids and derivatives
AEA00_RS11505	COG0671	phosphoesterase, PA-phosphatase related
AEA00_RS11520	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AEA00_RS11525	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA00_RS11530	COG5001	Diguanylate cyclase
AEA00_RS11530	COG4251	negative regulation of phosphorylation
AEA00_RS11530	COG2203	Gaf domain
AEA00_RS11530	COG3706	GGDEF domain
AEA00_RS11540	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA00_RS11600	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEA00_RS11620	COG0477	Major facilitator Superfamily
AEA00_RS11630	COG1070	Carbohydrate kinase
AEA00_RS11640	COG1501	Belongs to the glycosyl hydrolase 31 family
AEA00_RS11675	COG0800	Aldolase
AEA00_RS11690	COG3734	2-keto-3-deoxy-galactonokinase
AEA00_RS11695	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AEA00_RS11705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEA00_RS11720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEA00_RS11725	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AEA00_RS11735	COG0352	thiamine-phosphate diphosphorylase activity
AEA00_RS11735	COG0351	phosphomethylpyrimidine kinase
AEA00_RS11760	COG0583	DNA-binding transcription factor activity
AEA00_RS11765	COG1741	Belongs to the pirin family
AEA00_RS11785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEA00_RS11800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEA00_RS11815	COG4771	TonB-dependent receptor
AEA00_RS11820	COG1546	Belongs to the CinA family
AEA00_RS11825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEA00_RS11840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEA00_RS11845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEA00_RS11855	COG1534	Rna-binding protein
AEA00_RS11870	COG1238	metal cluster binding
AEA00_RS11885	COG2840	Smr protein MutS2
AEA00_RS11940	COG2134	cdp-diacylglycerol pyrophosphatase
AEA00_RS11965	COG1253	flavin adenine dinucleotide binding
AEA00_RS11980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AEA00_RS11985	COG0477	Major facilitator Superfamily
AEA00_RS11990	COG1132	(ABC) transporter
AEA00_RS12010	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS12015	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS12020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEA00_RS12025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AEA00_RS12050	COG2244	polysaccharide biosynthetic process
AEA00_RS12065	COG3038	cytochrome b561
AEA00_RS12100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEA00_RS12120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA00_RS12135	COG0784	Response regulator, receiver
AEA00_RS12135	COG4191	Histidine kinase
AEA00_RS12140	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AEA00_RS12185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AEA00_RS12210	COG2963	transposase activity
AEA00_RS12215	COG2801	Transposase and inactivated derivatives
AEA00_RS12225	COG2963	transposase activity
AEA00_RS12245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AEA00_RS12265	COG2963	transposase activity
AEA00_RS12270	COG3039	Transposase
AEA00_RS12280	COG2963	transposase activity
AEA00_RS12285	COG2963	transposase activity
AEA00_RS12290	COG2801	Transposase and inactivated derivatives
AEA00_RS12295	COG3039	Transposase
AEA00_RS12305	COG2963	transposase activity
AEA00_RS12310	COG2963	transposase activity
AEA00_RS12315	COG2801	Transposase and inactivated derivatives
AEA00_RS12320	COG2801	Transposase and inactivated derivatives
AEA00_RS12325	COG2963	transposase activity
AEA00_RS12335	COG0583	DNA-binding transcription factor activity
AEA00_RS12350	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AEA00_RS12360	COG0077	Prephenate dehydratase
AEA00_RS12360	COG1605	Chorismate mutase
AEA00_RS12370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEA00_RS12425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AEA00_RS12435	COG4993	Dehydrogenase
AEA00_RS12455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AEA00_RS12465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEA00_RS12500	COG0316	Belongs to the HesB IscA family
AEA00_RS12530	COG0288	reversible hydration of carbon dioxide
AEA00_RS12555	COG2925	Exonuclease
AEA00_RS12570	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AEA00_RS12590	COG0488	(ABC) transporter
AEA00_RS12595	COG2264	protein methyltransferase activity
AEA00_RS12630	COG0494	nUDIX hydrolase
AEA00_RS12640	COG1024	Enoyl-CoA hydratase
AEA00_RS12650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEA00_RS12655	COG0659	secondary active sulfate transmembrane transporter activity
AEA00_RS12680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEA00_RS12685	COG0573	inorganic phosphate transmembrane transporter activity
AEA00_RS12690	COG0581	inorganic phosphate transmembrane transporter activity
AEA00_RS12700	COG0704	Plays a role in the regulation of phosphate uptake
AEA00_RS12720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEA00_RS12730	COG0557	exoribonuclease II activity
AEA00_RS12745	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS12750	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS12755	COG2226	methyltransferase
AEA00_RS12760	COG1410	methionine synthase
AEA00_RS12760	COG0646	methionine synthase
AEA00_RS12765	COG0646	methionine synthase
AEA00_RS12765	COG1410	methionine synthase
AEA00_RS12775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA00_RS12785	COG1609	Transcriptional regulator
AEA00_RS12820	COG0386	Belongs to the glutathione peroxidase family
AEA00_RS12825	COG1725	Transcriptional regulator
AEA00_RS12830	COG1131	(ABC) transporter
AEA00_RS12870	COG2850	peptidyl-arginine hydroxylation
AEA00_RS12905	COG1132	(ABC) transporter
AEA00_RS12910	COG0583	DNA-binding transcription factor activity
AEA00_RS12915	COG2274	protein secretion by the type I secretion system
AEA00_RS12940	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AEA00_RS12955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEA00_RS12960	COG1420	regulation of RNA biosynthetic process
AEA00_RS12965	COG0497	DNA recombination
AEA00_RS12975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_RS12995	COG1404	Belongs to the peptidase S8 family
AEA00_RS13045	COG2963	transposase activity
AEA00_RS13060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEA00_RS13100	COG3706	GGDEF domain
AEA00_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS13130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA00_RS13140	COG0583	DNA-binding transcription factor activity
AEA00_RS13150	COG0415	Belongs to the DNA photolyase family
AEA00_RS13155	COG0305	Participates in initiation and elongation during chromosome replication
AEA00_RS13165	COG0367	asparagine synthase
AEA00_RS13180	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS13195	COG0084	hydrolase, TatD family'
AEA00_RS13200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AEA00_RS13260	COG0386	Belongs to the glutathione peroxidase family
AEA00_RS13265	COG0339	signal peptide processing
AEA00_RS13295	COG3104	oligopeptide transport
AEA00_RS13325	COG2814	Major facilitator Superfamily
AEA00_RS13330	COG1566	PFAM secretion protein HlyD family protein
AEA00_RS13370	COG4774	siderophore transport
AEA00_RS13380	COG0367	asparagine synthase
AEA00_RS13395	COG1393	Belongs to the ArsC family
AEA00_RS13465	COG0528	UMP kinase activity
AEA00_RS13475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AEA00_RS13480	COG0575	Belongs to the CDS family
AEA00_RS13490	COG0750	zinc metalloprotease
AEA00_RS13545	COG1981	membrane
AEA00_RS13565	COG1695	Transcriptional regulator
AEA00_RS13595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AEA00_RS13605	COG2040	homocysteine
AEA00_RS13610	COG0833	amino acid
AEA00_RS13620	COG0346	lactoylglutathione lyase activity
AEA00_RS13645	COG2878	Part of a membrane complex involved in electron transport
AEA00_RS13660	COG1595	DNA-templated transcription, initiation
AEA00_RS13685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEA00_RS13700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEA00_RS13705	COG0251	oxidation-reduction process
AEA00_RS13715	COG0392	lysyltransferase activity
AEA00_RS13715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AEA00_RS13750	COG2814	Major facilitator Superfamily
AEA00_RS13755	COG1902	pentaerythritol trinitrate reductase activity
AEA00_RS13775	COG2824	Alkylphosphonate utilization operon protein PhnA
AEA00_RS13785	COG1047	Peptidyl-prolyl cis-trans
AEA00_RS13820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEA00_RS13830	COG5487	UPF0391 membrane protein
AEA00_RS13835	COG1451	nucleotide metabolic process
AEA00_RS13855	COG0183	Belongs to the thiolase family
AEA00_RS13885	COG1793	dna ligase
AEA00_RS13885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEA00_RS13895	COG1793	dna ligase
AEA00_RS13900	COG1201	RNA secondary structure unwinding
AEA00_RS13910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA00_RS13915	COG1278	Cold shock
AEA00_RS13920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEA00_RS13925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AEA00_RS13935	COG3046	protein related to deoxyribodipyrimidine photolyase
AEA00_RS13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA00_RS13940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AEA00_RS13945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AEA00_RS13950	COG2954	triphosphatase activity
AEA00_RS14000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEA00_RS14030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AEA00_RS14035	COG1024	Enoyl-CoA hydratase
AEA00_RS14040	COG1960	acyl-CoA dehydrogenase activity
AEA00_RS14050	COG3800	Transcriptional regulator
AEA00_RS14050	COG1396	sequence-specific DNA binding
AEA00_RS14060	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AEA00_RS14065	COG3250	beta-galactosidase activity
AEA00_RS14105	COG3039	Transposase
AEA00_RS14200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AEA00_RS14255	COG5297	Belongs to the glycosyl hydrolase family 6
AEA00_RS14275	COG1309	transcriptional regulator
AEA00_RS14280	COG0436	Aminotransferase
AEA00_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS14290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEA00_RS14305	COG3483	tryptophan 2,3-dioxygenase activity
AEA00_RS14315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEA00_RS14335	COG0534	Mate efflux family protein
AEA00_RS14365	COG2070	2-Nitropropane dioxygenase
AEA00_RS14380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEA00_RS14385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEA00_RS14395	COG3534	alpha-L-arabinofuranosidase
AEA00_RS14420	COG0784	Response regulator, receiver
AEA00_RS14420	COG4191	Histidine kinase
AEA00_RS14425	COG3437	response regulator, receiver
AEA00_RS14425	COG3850	Histidine kinase
AEA00_RS14425	COG4999	Histidine kinase
AEA00_RS14425	COG2205	protein histidine kinase activity
AEA00_RS14430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEA00_RS14440	COG2205	protein histidine kinase activity
AEA00_RS14445	COG5507	3-demethylubiquinone-9 3-methyltransferase
AEA00_RS14455	COG4771	TonB-dependent receptor
AEA00_RS14490	COG2172	sigma factor antagonist activity
AEA00_RS14495	COG1366	Belongs to the anti-sigma-factor antagonist family
AEA00_RS14500	COG1366	Belongs to the anti-sigma-factor antagonist family
AEA00_RS14505	COG1902	pentaerythritol trinitrate reductase activity
AEA00_RS14515	COG0326	Molecular chaperone. Has ATPase activity
AEA00_RS14520	COG2207	Transcriptional regulator
AEA00_RS14530	COG3152	Membrane
AEA00_RS14545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AEA00_RS14550	COG1845	cytochrome c oxidase, subunit III
AEA00_RS14555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEA00_RS14585	COG0196	riboflavin kinase activity
AEA00_RS14590	COG0728	peptidoglycan biosynthetic process
AEA00_RS14615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEA00_RS14620	COG0824	Thioesterase
AEA00_RS14625	COG1024	Enoyl-CoA hydratase
AEA00_RS14630	COG1946	Acyl-CoA thioesterase
AEA00_RS14640	COG1595	DNA-templated transcription, initiation
AEA00_RS14700	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AEA00_RS14725	COG2197	response regulator
AEA00_RS14730	COG4585	Histidine kinase
AEA00_RS14740	COG0850	regulation of cytokinetic process
AEA00_RS14745	COG2894	cell division
AEA00_RS14760	COG5002	protein histidine kinase activity
AEA00_RS14765	COG0745	RESPONSE REGULATOR receiver
AEA00_RS14800	COG2814	Major facilitator Superfamily
AEA00_RS14825	COG0656	L-ascorbic acid biosynthetic process
AEA00_RS14830	COG0753	catalase activity
AEA00_RS14840	COG2207	Transcriptional regulator
AEA00_RS14840	COG1917	Cupin 2, conserved barrel domain protein
AEA00_RS14855	COG0823	Involved in the tonB-independent uptake of proteins
AEA00_RS14855	COG1506	peptidase
AEA00_RS14865	COG1297	OPT oligopeptide transporter protein
AEA00_RS14890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEA00_RS14915	COG2080	2 iron, 2 sulfur cluster binding
AEA00_RS14920	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEA00_RS14925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA00_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS14975	COG3537	Alpha-1,2-mannosidase
AEA00_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS14990	COG3387	PFAM Glycoside hydrolase 15-related
AEA00_RS15000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEA00_RS15035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEA00_RS15050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AEA00_RS15100	COG0308	aminopeptidase N
AEA00_RS15115	COG0330	HflC and HflK could
AEA00_RS15120	COG0330	HflC and HflK could
AEA00_RS15140	COG0678	peroxiredoxin activity
AEA00_RS15150	COG4953	penicillin-binding protein 1C
AEA00_RS15175	COG2373	Large extracellular alpha-helical protein
AEA00_RS15200	COG3609	addiction module antidote protein, CC2985 family
AEA00_RS15220	COG3829	transcription factor binding
AEA00_RS15260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AEA00_RS15265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEA00_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS15285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AEA00_RS15290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA00_RS15300	COG1399	metal-binding, possibly nucleic acid-binding protein
AEA00_RS15335	COG0714	Associated with various cellular activities
AEA00_RS15355	COG0537	adenosine 5'-monophosphoramidase activity
AEA00_RS15380	COG0314	molybdopterin synthase activity
AEA00_RS15385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AEA00_RS15405	COG1234	tRNA 3'-trailer cleavage
AEA00_RS15415	COG0859	PFAM glycosyl transferase family 9
AEA00_RS15430	COG0631	protein serine/threonine phosphatase activity
AEA00_RS15435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEA00_RS15540	COG0473	3-isopropylmalate dehydrogenase activity
AEA00_RS15555	COG4783	chaperone-mediated protein folding
AEA00_RS15560	COG0745	RESPONSE REGULATOR receiver
AEA00_RS15570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEA00_RS15580	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS15585	COG0671	phosphoesterase, PA-phosphatase related
AEA00_RS15590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEA00_RS15600	COG3291	Pkd domain containing protein
AEA00_RS15605	COG2833	Protein of unknown function (DUF455)
AEA00_RS15625	COG0285	dihydrofolate synthase activity
AEA00_RS15640	COG0406	alpha-ribazole phosphatase activity
AEA00_RS15665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEA00_RS15670	COG4208	sulfate ABC transporter
AEA00_RS15675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AEA00_RS15680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AEA00_RS15715	COG1902	pentaerythritol trinitrate reductase activity
AEA00_RS15715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEA00_RS15740	COG0625	glutathione transferase activity
AEA00_RS15750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEA00_RS15755	COG1217	gtp-binding protein TYPA
AEA00_RS15765	COG0154	amidase activity
AEA00_RS15775	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AEA00_RS15810	COG0201	protein transport
AEA00_RS15970	COG0250	Participates in transcription elongation, termination and antitermination
AEA00_RS16005	COG0012	GTP binding
AEA00_RS16010	COG0193	aminoacyl-tRNA hydrolase activity
AEA00_RS16020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEA00_RS16060	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEA00_RS16080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA00_RS16110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEA00_RS16115	COG1404	Belongs to the peptidase S8 family
AEA00_RS16120	COG1404	Belongs to the peptidase S8 family
AEA00_RS16125	COG1404	Belongs to the peptidase S8 family
AEA00_RS16130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEA00_RS16180	COG0778	Nitroreductase
AEA00_RS16185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEA00_RS16185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEA00_RS16205	COG2890	protein-(glutamine-N5) methyltransferase activity
AEA00_RS16215	COG3634	alkyl hydroperoxide reductase activity
AEA00_RS16220	COG0583	DNA-binding transcription factor activity
AEA00_RS16225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA00_RS16250	COG2197	response regulator
AEA00_RS16255	COG0784	Response regulator, receiver
AEA00_RS16255	COG2205	protein histidine kinase activity
AEA00_RS16255	COG5002	protein histidine kinase activity
AEA00_RS16285	COG0697	spore germination
AEA00_RS16315	COG3386	PFAM SMP-30 Gluconolaconase
AEA00_RS16335	COG1024	Enoyl-CoA hydratase
AEA00_RS16345	COG0318	PFAM AMP-dependent synthetase and ligase
AEA00_RS16350	COG0583	DNA-binding transcription factor activity
AEA00_RS16355	COG3384	dioxygenase
AEA00_RS16385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA00_RS16390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA00_RS16400	COG2096	Adenosyltransferase
AEA00_RS16405	COG0123	including yeast histone deacetylase and acetoin utilization protein
AEA00_RS16435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AEA00_RS16470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AEA00_RS16480	COG0642	Histidine kinase
AEA00_RS16495	COG4181	ATPase activity
AEA00_RS16505	COG2175	clavaminate synthase activity
AEA00_RS16515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AEA00_RS16540	COG4771	TonB-dependent receptor
AEA00_RS16550	COG0667	Aldo Keto reductase
AEA00_RS16555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AEA00_RS16565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AEA00_RS16650	COG0366	Alpha amylase catalytic
AEA00_RS16680	COG3321	synthase
AEA00_RS16680	COG0604	alcohol dehydrogenase
AEA00_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS16695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEA00_RS16710	COG0494	nUDIX hydrolase
AEA00_RS16725	COG0739	heme binding
AEA00_RS16750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEA00_RS16755	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEA00_RS16780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEA00_RS16795	COG3116	cell division
AEA00_RS16840	COG1988	membrane-bound metal-dependent
AEA00_RS16845	COG0277	FAD linked oxidase domain protein
AEA00_RS16855	COG0745	RESPONSE REGULATOR receiver
AEA00_RS16860	COG2205	protein histidine kinase activity
AEA00_RS16870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AEA00_RS16875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEA00_RS16890	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEA00_RS16920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEA00_RS16920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEA00_RS16945	COG0488	(ABC) transporter
AEA00_RS16950	COG0242	peptide deformylase activity
AEA00_RS16955	COG1393	Belongs to the ArsC family
AEA00_RS16970	COG0457	Tetratricopeptide repeat
AEA00_RS17020	COG2188	Transcriptional regulator
AEA00_RS17030	COG1450	Type ii and iii secretion system protein
AEA00_RS17045	COG3166	PFAM Fimbrial assembly family protein
AEA00_RS17050	COG3156	type II secretion system protein K
AEA00_RS17055	COG4795	General secretion pathway protein
AEA00_RS17060	COG2165	general secretion pathway protein
AEA00_RS17065	COG4970	Tfp pilus assembly protein FimT
AEA00_RS17070	COG2165	general secretion pathway protein
AEA00_RS17075	COG1459	type II secretion system
AEA00_RS17080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AEA00_RS17085	COG1404	Belongs to the peptidase S8 family
AEA00_RS17105	COG0047	phosphoribosylformylglycinamidine synthase activity
AEA00_RS17105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEA00_RS17110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEA00_RS17115	COG4974	Belongs to the 'phage' integrase family
AEA00_RS17130	COG0795	lipopolysaccharide-transporting ATPase activity
AEA00_RS17185	COG1183	phosphatidylcholine synthase activity
AEA00_RS17210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEA00_RS17215	COG1127	ABC transporter
AEA00_RS17220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEA00_RS17220	COG3218	ABC-type transport auxiliary lipoprotein component
AEA00_RS17240	COG3754	Rhamnan synthesis protein F
AEA00_RS17245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEA00_RS17250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEA00_RS17255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEA00_RS17260	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AEA00_RS17260	COG0662	Cupin 2, conserved barrel domain protein
AEA00_RS17285	COG2086	electron transfer activity
AEA00_RS17295	COG0662	Cupin 2, conserved barrel domain protein
AEA00_RS17295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AEA00_RS17300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEA00_RS17305	COG0463	Glycosyl transferase, family 2
AEA00_RS17330	COG2963	transposase activity
AEA00_RS17335	COG2801	Transposase and inactivated derivatives
AEA00_RS17340	COG3039	Transposase
AEA00_RS17350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AEA00_RS17365	COG0438	transferase activity, transferring glycosyl groups
AEA00_RS17390	COG0626	cystathionine gamma-synthase activity
AEA00_RS17420	COG0625	glutathione transferase activity
AEA00_RS17430	COG0513	Belongs to the DEAD box helicase family
AEA00_RS17435	COG0720	synthase
AEA00_RS17450	COG1956	GAF domain-containing protein
AEA00_RS17480	COG0339	signal peptide processing
AEA00_RS17485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEA00_RS17530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEA00_RS17540	COG1136	(ABC) transporter
AEA00_RS17550	COG0577	efflux transmembrane transporter activity
AEA00_RS17550	COG1136	(ABC) transporter
AEA00_RS17570	COG2963	transposase activity
AEA00_RS17575	COG2801	Transposase and inactivated derivatives
AEA00_RS17635	COG0356	it plays a direct role in the translocation of protons across the membrane
AEA00_RS17650	COG1228	amidohydrolase
AEA00_RS17655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEA00_RS17665	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEA00_RS17705	COG2011	ABC-type metal ion transport system permease component
AEA00_RS17715	COG0697	spore germination
AEA00_RS17745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEA00_RS17750	COG1187	pseudouridine synthase activity
AEA00_RS17755	COG2813	Specifically methylates the guanine in position
AEA00_RS17775	COG5002	protein histidine kinase activity
AEA00_RS17855	COG0842	Transport permease protein
AEA00_RS17860	COG1131	(ABC) transporter
AEA00_RS17865	COG0025	NhaP-type Na H and K H
AEA00_RS17870	COG3795	YCII-related domain
AEA00_RS17875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEA00_RS17880	COG1573	uracil-dna glycosylase
AEA00_RS17890	COG3384	dioxygenase
AEA00_RS17895	COG0583	DNA-binding transcription factor activity
AEA00_RS17905	COG0667	Aldo Keto reductase
AEA00_RS17915	COG3590	peptidase
AEA00_RS17930	COG0531	amino acid
AEA00_RS17945	COG2972	Histidine kinase
AEA00_RS17960	COG1335	isochorismatase
AEA00_RS17965	COG3685	Protein conserved in bacteria
AEA00_RS17970	COG3685	Protein conserved in bacteria
AEA00_RS17975	COG3546	catalase activity
AEA00_RS18005	COG2204	response regulator
AEA00_RS18015	COG1271	oxidase subunit
AEA00_RS18020	COG1294	oxidase, subunit
AEA00_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS18040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEA00_RS18060	COG1132	(ABC) transporter
AEA00_RS18075	COG1063	alcohol dehydrogenase
AEA00_RS18100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA00_RS18155	COG0251	oxidation-reduction process
AEA00_RS18175	COG0667	Aldo Keto reductase
AEA00_RS18180	COG0583	DNA-binding transcription factor activity
AEA00_RS18200	COG3706	GGDEF domain
AEA00_RS18200	COG4251	negative regulation of phosphorylation
AEA00_RS18200	COG5001	Diguanylate cyclase
AEA00_RS18200	COG2203	Gaf domain
AEA00_RS18230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEA00_RS18240	COG1560	Kdo2-lipid A biosynthetic process
AEA00_RS18250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEA00_RS18285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEA00_RS18285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEA00_RS18295	COG0242	peptide deformylase activity
AEA00_RS18300	COG1652	LysM domain
AEA00_RS18305	COG0758	DNA mediated transformation
AEA00_RS18325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEA00_RS18325	COG1754	DNA topoisomerase type I activity
AEA00_RS18345	COG3706	GGDEF domain
AEA00_RS18345	COG4251	negative regulation of phosphorylation
AEA00_RS18345	COG2203	Gaf domain
AEA00_RS18345	COG5001	Diguanylate cyclase
AEA00_RS18350	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS18360	COG0616	signal peptide processing
AEA00_RS18365	COG0534	Mate efflux family protein
AEA00_RS18380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEA00_RS18400	COG1252	NADH dehydrogenase
AEA00_RS18405	COG2860	membrane
AEA00_RS18410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEA00_RS18420	COG2201	protein-glutamate methylesterase activity
AEA00_RS18425	COG2177	Part of the ABC transporter FtsEX involved in
AEA00_RS18430	COG2884	Cell division ATP-binding protein ftsE
AEA00_RS18440	COG3118	belongs to the thioredoxin family
AEA00_RS18445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AEA00_RS18490	COG1473	amidohydrolase
AEA00_RS18495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA00_RS18525	COG4941	Belongs to the sigma-70 factor family
AEA00_RS18530	COG5383	Protein conserved in bacteria
AEA00_RS18570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AEA00_RS18575	COG3409	Peptidoglycan-binding domain 1 protein
AEA00_RS18575	COG3501	Rhs element vgr protein
AEA00_RS18590	COG3023	N-Acetylmuramoyl-L-alanine amidase
AEA00_RS18600	COG4948	Mandelate Racemase Muconate Lactonizing
AEA00_RS18610	COG0531	amino acid
AEA00_RS18625	COG4682	membrane
AEA00_RS18630	COG2133	pyrroloquinoline quinone binding
AEA00_RS18640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AEA00_RS18655	COG1610	YqeY-like protein
AEA00_RS18660	COG1295	ribonuclease BN
AEA00_RS18665	COG0358	DNA primase activity
AEA00_RS18715	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AEA00_RS18730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEA00_RS18780	COG2963	transposase activity
AEA00_RS18790	COG2801	Transposase and inactivated derivatives
AEA00_RS18795	COG2963	transposase activity
AEA00_RS18805	COG2801	Transposase and inactivated derivatives
AEA00_RS18810	COG2963	transposase activity
AEA00_RS18820	COG3039	Transposase
AEA00_RS18860	COG0739	heme binding
AEA00_RS18880	COG0708	Exodeoxyribonuclease III
AEA00_RS18895	COG1192	Involved in chromosome partitioning
AEA00_RS18900	COG1475	DNA binding
AEA00_RS18920	COG0463	Glycosyl transferase, family 2
AEA00_RS18945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEA00_RS18970	COG4221	oxidoreductase activity
AEA00_RS18975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEA00_RS18975	COG2755	lipolytic protein G-D-S-L family
AEA00_RS18995	COG1166	arginine decarboxylase activity
AEA00_RS19020	COG2960	long-chain fatty acid transporting porin activity
AEA00_RS19025	COG0606	chelatase, subunit chli
AEA00_RS19040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AEA00_RS19075	COG1690	Belongs to the RtcB family
AEA00_RS19110	COG1090	epimerase
AEA00_RS19115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEA00_RS19130	COG0642	Histidine kinase
AEA00_RS19150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEA00_RS19175	COG1011	Hydrolase
AEA00_RS19180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEA00_RS19200	COG2197	response regulator
AEA00_RS19215	COG1136	(ABC) transporter
AEA00_RS19240	COG0697	spore germination
AEA00_RS19270	COG0180	Tryptophanyl-tRNA synthetase
AEA00_RS19275	COG3237	CsbD-like
AEA00_RS19350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AEA00_RS19350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AEA00_RS19360	COG3228	Belongs to the MtfA family
AEA00_RS19390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AEA00_RS19415	COG1199	ATP-dependent helicase activity
AEA00_RS19470	COG0625	glutathione transferase activity
AEA00_RS19505	COG4555	ABC transporter
AEA00_RS19515	COG1476	TRANSCRIPTIONal
AEA00_RS19530	COG1230	cation diffusion facilitator family transporter
AEA00_RS19540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AEA00_RS19545	COG1131	(ABC) transporter
AEA00_RS19550	COG0842	Transport permease protein
AEA00_RS19560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AEA00_RS19570	COG1607	acyl-coa hydrolase
AEA00_RS19575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEA00_RS19580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEA00_RS19590	COG0045	succinate-CoA ligase (ADP-forming) activity
AEA00_RS19590	COG1042	CoA-binding domain protein
AEA00_RS19590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEA00_RS19595	COG2239	Acts as a magnesium transporter
AEA00_RS19610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEA00_RS19615	COG3387	PFAM Glycoside hydrolase 15-related
AEA00_RS19630	COG3100	YcgL domain-containing protein
AEA00_RS19635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEA00_RS19645	COG0463	Glycosyl transferase, family 2
AEA00_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS19690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEA00_RS19705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEA00_RS19780	COG0210	DNA helicase
AEA00_RS19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS19795	COG0583	DNA-binding transcription factor activity
AEA00_RS19800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AEA00_RS19810	COG2159	amidohydrolase
AEA00_RS19870	COG2091	lysine biosynthetic process via aminoadipic acid
AEA00_RS19920	COG1940	carbohydrate kinase activity
AEA00_RS19930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEA00_RS19940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEA00_RS19945	COG3162	membrane
AEA00_RS19985	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA00_RS20000	COG1028	Short-chain dehydrogenase reductase Sdr
AEA00_RS20005	COG0179	Fumarylacetoacetate (FAA) hydrolase
AEA00_RS20010	COG4948	Mandelate Racemase Muconate Lactonizing
AEA00_RS20015	COG3254	rhamnose metabolic process
AEA00_RS20020	COG0738	Major facilitator superfamily
AEA00_RS20025	COG1414	Transcriptional regulator
AEA00_RS20045	COG2205	protein histidine kinase activity
AEA00_RS20045	COG0784	Response regulator, receiver
AEA00_RS20050	COG3459	Glycosyltransferase 36 associated
AEA00_RS20055	COG2211	Major facilitator Superfamily
AEA00_RS20060	COG3265	gluconokinase activity
AEA00_RS20065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_RS20085	COG2911	Protein conserved in bacteria
AEA00_RS20090	COG0729	surface antigen
AEA00_RS20105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AEA00_RS20110	COG0519	Catalyzes the synthesis of GMP from XMP
AEA00_RS20110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEA00_RS20120	COG0805	protein transport
AEA00_RS20140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEA00_RS20180	COG3661	Belongs to the glycosyl hydrolase 67 family
AEA00_RS20190	COG4948	Mandelate Racemase Muconate Lactonizing
AEA00_RS20200	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA00_RS20205	COG0246	Mannitol dehydrogenase
AEA00_RS20240	COG3386	PFAM SMP-30 Gluconolaconase
AEA00_RS20255	COG3250	beta-galactosidase activity
AEA00_RS20265	COG3693	PFAM glycoside hydrolase, family 10
AEA00_RS20280	COG2211	Major facilitator Superfamily
AEA00_RS20350	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AEA00_RS20370	COG0210	DNA helicase
AEA00_RS20375	COG2963	transposase activity
AEA00_RS20435	COG3135	benzoate transporter
AEA00_RS20455	COG0676	glucose-6-phosphate 1-epimerase activity
AEA00_RS20475	COG0730	response to heat
AEA00_RS20500	COG0302	gtp cyclohydrolase
AEA00_RS20515	COG1566	PFAM secretion protein HlyD family protein
AEA00_RS20525	COG1289	transmembrane transporter activity
AEA00_RS20530	COG0477	Major facilitator Superfamily
AEA00_RS20540	COG0583	DNA-binding transcription factor activity
AEA00_RS20545	COG4221	oxidoreductase activity
AEA00_RS20550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA00_RS20590	COG3039	Transposase
AEA00_RS20625	COG0564	pseudouridine synthase activity
AEA00_RS20665	COG1074	ATP-dependent DNA helicase activity
AEA00_RS20670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AEA00_RS20705	COG1127	ABC transporter
AEA00_RS20710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEA00_RS20715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEA00_RS20730	COG2853	Lipoprotein
AEA00_RS20735	COG0386	Belongs to the glutathione peroxidase family
AEA00_RS20750	COG1322	Protein conserved in bacteria
AEA00_RS20755	COG0604	alcohol dehydrogenase
AEA00_RS20760	COG0583	DNA-binding transcription factor activity
AEA00_RS20775	COG0531	amino acid
AEA00_RS20785	COG4206	TonB-dependent receptor
AEA00_RS20795	COG3706	GGDEF domain
AEA00_RS20800	COG3835	regulator
AEA00_RS20805	COG1929	Belongs to the glycerate kinase type-1 family
AEA00_RS20810	COG2271	Major facilitator Superfamily
AEA00_RS20830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AEA00_RS20835	COG0861	Integral membrane protein TerC family
AEA00_RS20850	COG0584	glycerophosphoryl diester phosphodiesterase
AEA00_RS20860	COG0671	phosphoesterase, PA-phosphatase related
AEA00_RS20875	COG0726	polysaccharide deacetylase
AEA00_RS20880	COG0706	membrane insertase activity