locus-tag	class	description
AEA01_RS00005	COG0584	glycerophosphoryl diester phosphodiesterase
AEA01_RS00015	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS00030	COG0726	polysaccharide deacetylase
AEA01_RS00035	COG0706	membrane insertase activity
AEA01_RS00065	COG0187	DNA topoisomerase II activity
AEA01_RS00075	COG0501	Belongs to the peptidase M48B family
AEA01_RS00115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS00150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEA01_RS00155	COG0793	Belongs to the peptidase S41A family
AEA01_RS00160	COG4942	peptidase
AEA01_RS00170	COG2234	aminopeptidase activity
AEA01_RS00180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA01_RS00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA01_RS00190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA01_RS00195	COG1064	alcohol dehydrogenase
AEA01_RS00200	COG0493	'glutamate synthase
AEA01_RS00205	COG0067	glutamate synthase
AEA01_RS00205	COG0070	glutamate synthase
AEA01_RS00205	COG0069	glutamate synthase activity
AEA01_RS00220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEA01_RS00230	COG1741	Belongs to the pirin family
AEA01_RS00235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEA01_RS00255	COG0583	DNA-binding transcription factor activity
AEA01_RS00310	COG1111	helicase
AEA01_RS00310	COG1205	dead DEAH box helicase
AEA01_RS00315	COG3177	Filamentation induced by cAMP protein fic
AEA01_RS00320	COG1272	protein, Hemolysin III
AEA01_RS00365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AEA01_RS00370	COG3237	CsbD-like
AEA01_RS00415	COG0628	permease
AEA01_RS00420	COG0657	acetylesterase activity
AEA01_RS00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA01_RS00435	COG0477	Major facilitator Superfamily
AEA01_RS00475	COG0714	Associated with various cellular activities
AEA01_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
AEA01_RS00560	COG1755	Isoprenylcysteine carboxyl methyltransferase
AEA01_RS00565	COG4585	Histidine kinase
AEA01_RS00570	COG2197	response regulator
AEA01_RS00595	COG3710	Transcriptional regulator
AEA01_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA01_RS00645	COG3039	Transposase
AEA01_RS00670	COG0366	Alpha amylase catalytic
AEA01_RS00675	COG0366	Alpha amylase catalytic
AEA01_RS00720	COG2755	lipolytic protein G-D-S-L family
AEA01_RS00730	COG0657	acetylesterase activity
AEA01_RS00730	COG2755	lipolytic protein G-D-S-L family
AEA01_RS00740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AEA01_RS00755	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA01_RS00760	COG1609	Transcriptional regulator
AEA01_RS00770	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS00780	COG2755	lipolytic protein G-D-S-L family
AEA01_RS00790	COG3186	Phenylalanine-4-hydroxylase
AEA01_RS00795	COG1522	sequence-specific DNA binding
AEA01_RS00805	COG1752	Esterase of the alpha-beta hydrolase superfamily
AEA01_RS00815	COG1119	ATPase activity
AEA01_RS00830	COG1125	glycine betaine transport
AEA01_RS00830	COG0517	IMP dehydrogenase activity
AEA01_RS00845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEA01_RS00850	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AEA01_RS00880	COG0489	protein tyrosine kinase activity
AEA01_RS00885	COG0588	phosphoglycerate mutase activity
AEA01_RS00895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS00920	COG1881	PFAM PEBP family protein
AEA01_RS00935	COG0174	glutamine synthetase
AEA01_RS00940	COG0347	Belongs to the P(II) protein family
AEA01_RS00945	COG0004	ammonium transporteR
AEA01_RS00950	COG3852	Histidine kinase
AEA01_RS00955	COG2204	response regulator
AEA01_RS00965	COG2032	superoxide dismutase activity
AEA01_RS00970	COG2032	superoxide dismutase activity
AEA01_RS00975	COG0346	lactoylglutathione lyase activity
AEA01_RS00985	COG0183	Belongs to the thiolase family
AEA01_RS01025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AEA01_RS01045	COG0028	Belongs to the TPP enzyme family
AEA01_RS01055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AEA01_RS01070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA01_RS01075	COG3177	Filamentation induced by cAMP protein fic
AEA01_RS01085	COG0596	Alpha beta hydrolase
AEA01_RS01090	COG0727	PFAM Uncharacterised protein family (UPF0153)
AEA01_RS01095	COG0318	PFAM AMP-dependent synthetase and ligase
AEA01_RS01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEA01_RS01115	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEA01_RS01130	COG0564	pseudouridine synthase activity
AEA01_RS01150	COG1446	asparaginase
AEA01_RS01155	COG0339	signal peptide processing
AEA01_RS01175	COG0583	DNA-binding transcription factor activity
AEA01_RS01180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AEA01_RS01185	COG2224	Isocitrate lyase
AEA01_RS01215	COG4770	biotin carboxylase activity
AEA01_RS01220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEA01_RS01225	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS01290	COG0697	spore germination
AEA01_RS01300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AEA01_RS01310	COG1846	Transcriptional regulator
AEA01_RS01315	COG1764	response to oxidative stress
AEA01_RS01340	COG0656	L-ascorbic acid biosynthetic process
AEA01_RS01345	COG2130	NADP-dependent
AEA01_RS01360	COG1187	pseudouridine synthase activity
AEA01_RS01370	COG1643	Atp-dependent helicase
AEA01_RS01375	COG0840	transmembrane signaling receptor activity
AEA01_RS01380	COG4807	Protein conserved in bacteria
AEA01_RS01385	COG2351	hydroxyisourate hydrolase activity
AEA01_RS01390	COG2072	flavoprotein involved in K transport
AEA01_RS01410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AEA01_RS01440	COG3568	Endonuclease Exonuclease Phosphatase
AEA01_RS01445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS01460	COG1957	nucleoside hydrolase
AEA01_RS01470	COG2252	PERMEase
AEA01_RS01490	COG0084	hydrolase, TatD family'
AEA01_RS01500	COG0583	DNA-binding transcription factor activity
AEA01_RS01505	COG2814	Major facilitator Superfamily
AEA01_RS01525	COG1902	pentaerythritol trinitrate reductase activity
AEA01_RS01550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEA01_RS01555	COG0583	DNA-binding transcription factor activity
AEA01_RS01585	COG0702	epimerase
AEA01_RS01590	COG1733	regulation of RNA biosynthetic process
AEA01_RS01600	COG0840	transmembrane signaling receptor activity
AEA01_RS01740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AEA01_RS01795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AEA01_RS01820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEA01_RS01825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEA01_RS01835	COG3485	protocatechuate 3,4-dioxygenase
AEA01_RS01840	COG3485	protocatechuate 3,4-dioxygenase
AEA01_RS01850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA01_RS01855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AEA01_RS01865	COG1414	Transcriptional regulator
AEA01_RS01875	COG0657	acetylesterase activity
AEA01_RS01895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEA01_RS01945	COG1040	competence protein
AEA01_RS01960	COG0582	viral genome integration into host DNA
AEA01_RS01970	COG4774	siderophore transport
AEA01_RS01980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEA01_RS01990	COG4206	TonB-dependent receptor
AEA01_RS02005	COG2963	transposase activity
AEA01_RS02010	COG2801	Transposase and inactivated derivatives
AEA01_RS02020	COG1511	domain protein
AEA01_RS02020	COG3264	Mechanosensitive ion channel
AEA01_RS02035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEA01_RS02040	COG2354	Protein conserved in bacteria
AEA01_RS02045	COG1649	PFAM Uncharacterised BCR, COG1649
AEA01_RS02055	COG0297	glycogen (starch) synthase activity
AEA01_RS02065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEA01_RS02090	COG0702	epimerase
AEA01_RS02130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA01_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS02145	COG0513	Belongs to the DEAD box helicase family
AEA01_RS02155	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEA01_RS02170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEA01_RS02185	COG3104	oligopeptide transport
AEA01_RS02205	COG2852	Protein conserved in bacteria
AEA01_RS02230	COG1320	monovalent cation:proton antiporter activity
AEA01_RS02235	COG2212	antiporter activity
AEA01_RS02245	COG0651	ATP synthesis coupled electron transport
AEA01_RS02250	COG1006	Multisubunit Na H antiporter MnhC subunit
AEA01_RS02255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEA01_RS02255	COG2111	Na H antiporter
AEA01_RS02325	COG0436	Aminotransferase
AEA01_RS02335	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEA01_RS02365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEA01_RS02470	COG2816	NAD+ diphosphatase activity
AEA01_RS02475	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AEA01_RS02500	COG2814	Major facilitator Superfamily
AEA01_RS02505	COG1289	transmembrane transporter activity
AEA01_RS02510	COG0151	Belongs to the GarS family
AEA01_RS02520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEA01_RS02525	COG2267	carboxylic ester hydrolase activity
AEA01_RS02530	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS02530	COG2453	phosphatase
AEA01_RS02555	COG4589	Belongs to the CDS family
AEA01_RS02560	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AEA01_RS02595	COG0439	Biotin carboxylase
AEA01_RS02605	COG0511	ligase activity, forming carbon-carbon bonds
AEA01_RS02620	COG1324	tolerance protein
AEA01_RS02625	COG2356	endonuclease I
AEA01_RS02640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEA01_RS02650	COG1196	nuclear chromosome segregation
AEA01_RS02680	COG3550	peptidyl-serine autophosphorylation
AEA01_RS02685	COG2963	transposase activity
AEA01_RS02695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AEA01_RS02720	COG3386	PFAM SMP-30 Gluconolaconase
AEA01_RS02735	COG3712	iron ion homeostasis
AEA01_RS02770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AEA01_RS02795	COG2353	YceI-like domain
AEA01_RS02850	COG1802	Transcriptional regulator
AEA01_RS02935	COG0435	Glutathione S-transferase
AEA01_RS02995	COG2409	Drug exporters of the RND superfamily
AEA01_RS03005	COG1506	peptidase
AEA01_RS03005	COG0823	Involved in the tonB-independent uptake of proteins
AEA01_RS03020	COG1959	2 iron, 2 sulfur cluster binding
AEA01_RS03060	COG0697	spore germination
AEA01_RS03075	COG4305	rare lipoprotein A
AEA01_RS03080	COG5297	Belongs to the glycosyl hydrolase family 6
AEA01_RS03085	COG1113	amino acid transport
AEA01_RS03135	COG5002	protein histidine kinase activity
AEA01_RS03135	COG3447	MASE1 domain protein
AEA01_RS03135	COG5001	Diguanylate cyclase
AEA01_RS03140	COG0840	transmembrane signaling receptor activity
AEA01_RS03145	COG5297	Belongs to the glycosyl hydrolase family 6
AEA01_RS03145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA01_RS03150	COG0659	secondary active sulfate transmembrane transporter activity
AEA01_RS03170	COG3273	potassium ion transport
AEA01_RS03170	COG0471	metal ion transport
AEA01_RS03185	COG3275	phosphorelay sensor kinase activity
AEA01_RS03220	COG1505	serine-type exopeptidase activity
AEA01_RS03235	COG0436	Aminotransferase
AEA01_RS03245	COG2832	Protein of unknown function (DUF454)
AEA01_RS03275	COG2963	transposase activity
AEA01_RS03315	COG2226	methyltransferase
AEA01_RS03320	COG3300	MHYT domain
AEA01_RS03320	COG5001	Diguanylate cyclase
AEA01_RS03325	COG0308	aminopeptidase N
AEA01_RS03345	COG2963	transposase activity
AEA01_RS03375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AEA01_RS03390	COG3284	Transcriptional regulator
AEA01_RS03395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA01_RS03400	COG1077	Cell shape determining protein MreB Mrl
AEA01_RS03405	COG1792	Involved in formation and maintenance of cell shape
AEA01_RS03420	COG0772	Belongs to the SEDS family
AEA01_RS03430	COG2963	transposase activity
AEA01_RS03435	COG2801	Transposase and inactivated derivatives
AEA01_RS03475	COG2951	lytic endotransglycosylase activity
AEA01_RS03480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEA01_RS03485	COG1686	Belongs to the peptidase S11 family
AEA01_RS03535	COG1056	cytidyltransferase-related domain
AEA01_RS03535	COG1051	belongs to the nudix hydrolase family
AEA01_RS03570	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AEA01_RS03575	COG0673	inositol 2-dehydrogenase activity
AEA01_RS03580	COG2823	Periplasmic or secreted lipoprotein
AEA01_RS03585	COG4251	negative regulation of phosphorylation
AEA01_RS03590	COG0784	Response regulator, receiver
AEA01_RS03595	COG4191	Histidine kinase
AEA01_RS03600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AEA01_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS03650	COG1459	type II secretion system
AEA01_RS03665	COG2165	general secretion pathway protein
AEA01_RS03670	COG4795	General secretion pathway protein
AEA01_RS03695	COG2188	Transcriptional regulator
AEA01_RS03705	COG1609	Transcriptional regulator
AEA01_RS03710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEA01_RS03715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AEA01_RS03755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AEA01_RS03765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEA01_RS03790	COG2205	protein histidine kinase activity
AEA01_RS03815	COG0583	DNA-binding transcription factor activity
AEA01_RS03835	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AEA01_RS03840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEA01_RS03845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEA01_RS03855	COG0697	spore germination
AEA01_RS03865	COG1307	EDD domain protein, DegV family
AEA01_RS03905	COG0402	S-adenosylhomocysteine deaminase activity
AEA01_RS03925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEA01_RS03945	COG0436	Aminotransferase
AEA01_RS03980	COG2211	Major facilitator Superfamily
AEA01_RS03985	COG1609	Transcriptional regulator
AEA01_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS03995	COG2851	Citrate transporter
AEA01_RS04010	COG0642	Histidine kinase
AEA01_RS04025	COG2197	response regulator
AEA01_RS04035	COG4191	Histidine kinase
AEA01_RS04075	COG1560	Kdo2-lipid A biosynthetic process
AEA01_RS04080	COG1519	Transferase
AEA01_RS04085	COG1538	Outer membrane efflux protein
AEA01_RS04090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEA01_RS04100	COG3300	MHYT domain
AEA01_RS04100	COG5001	Diguanylate cyclase
AEA01_RS04110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEA01_RS04120	COG2226	methyltransferase
AEA01_RS04155	COG0405	Gamma-glutamyltransferase
AEA01_RS04160	COG0840	transmembrane signaling receptor activity
AEA01_RS04165	COG4946	Tricorn protease homolog
AEA01_RS04165	COG0823	Involved in the tonB-independent uptake of proteins
AEA01_RS04165	COG1506	peptidase
AEA01_RS04180	COG3710	Transcriptional regulator
AEA01_RS04200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEA01_RS04210	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEA01_RS04245	COG2963	transposase activity
AEA01_RS04310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEA01_RS04320	COG3781	membrane
AEA01_RS04325	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS04345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEA01_RS04350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEA01_RS04380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEA01_RS04410	COG1773	rubredoxin
AEA01_RS04415	COG2912	Transglutaminase-like superfamily
AEA01_RS04435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEA01_RS04465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEA01_RS04465	COG3453	Protein conserved in bacteria
AEA01_RS04480	COG0725	ABC transporter, periplasmic molybdate-binding protein
AEA01_RS04485	COG4149	molybdate abc transporter
AEA01_RS04530	COG1376	ErfK ybiS ycfS ynhG family protein
AEA01_RS04535	COG0739	heme binding
AEA01_RS04540	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS04545	COG0583	DNA-binding transcription factor activity
AEA01_RS04555	COG2963	transposase activity
AEA01_RS04560	COG2801	Transposase and inactivated derivatives
AEA01_RS04565	COG0596	Alpha beta hydrolase
AEA01_RS04570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AEA01_RS04575	COG1301	dicarboxylic acid transport
AEA01_RS04585	COG2304	oxidoreductase activity
AEA01_RS04605	COG0714	Associated with various cellular activities
AEA01_RS04635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEA01_RS04660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEA01_RS04670	COG2721	sulfolactate sulfo-lyase activity
AEA01_RS04685	COG2271	Major facilitator Superfamily
AEA01_RS04700	COG0583	DNA-binding transcription factor activity
AEA01_RS04705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEA01_RS04720	COG1561	YicC-like family, N-terminal region
AEA01_RS04730	COG0346	lactoylglutathione lyase activity
AEA01_RS04740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEA01_RS04765	COG3047	cAMP biosynthetic process
AEA01_RS04780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEA01_RS04810	COG0469	pyruvate kinase activity
AEA01_RS04815	COG3588	fructose-bisphosphate aldolase
AEA01_RS04820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AEA01_RS04850	COG2205	protein histidine kinase activity
AEA01_RS04850	COG2198	Histidine kinase
AEA01_RS04850	COG0784	Response regulator, receiver
AEA01_RS04880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AEA01_RS04890	COG0529	Catalyzes the synthesis of activated sulfate
AEA01_RS04890	COG2895	sulfate adenylyltransferase (ATP) activity
AEA01_RS04895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA01_RS04900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA01_RS04905	COG0308	aminopeptidase N
AEA01_RS04915	COG1115	amino acid carrier protein
AEA01_RS04920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEA01_RS04925	COG2272	Belongs to the type-B carboxylesterase lipase family
AEA01_RS04930	COG4948	Mandelate Racemase Muconate Lactonizing
AEA01_RS04935	COG3250	beta-galactosidase activity
AEA01_RS04945	COG5297	Belongs to the glycosyl hydrolase family 6
AEA01_RS04950	COG1609	Transcriptional regulator
AEA01_RS04985	COG3273	potassium ion transport
AEA01_RS04985	COG0471	metal ion transport
AEA01_RS05015	COG0582	viral genome integration into host DNA
AEA01_RS05035	COG1396	sequence-specific DNA binding
AEA01_RS05050	COG2801	Transposase and inactivated derivatives
AEA01_RS05055	COG2963	transposase activity
AEA01_RS05080	COG2963	transposase activity
AEA01_RS05090	COG2801	Transposase and inactivated derivatives
AEA01_RS05095	COG2963	transposase activity
AEA01_RS05110	COG5001	Diguanylate cyclase
AEA01_RS05185	COG0745	RESPONSE REGULATOR receiver
AEA01_RS05220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AEA01_RS05225	COG1459	type II secretion system
AEA01_RS05275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEA01_RS05275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEA01_RS05285	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_RS05290	COG0564	pseudouridine synthase activity
AEA01_RS05295	COG1496	oxidoreductase activity
AEA01_RS05310	COG0840	transmembrane signaling receptor activity
AEA01_RS05325	COG3387	PFAM Glycoside hydrolase 15-related
AEA01_RS05330	COG1877	trehalose-phosphatase activity
AEA01_RS05375	COG1116	anion transmembrane transporter activity
AEA01_RS05380	COG0542	response to heat
AEA01_RS05395	COG4206	TonB-dependent receptor
AEA01_RS05415	COG1797	cobyrinic acid a,c-diamide synthase activity
AEA01_RS05420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AEA01_RS05450	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AEA01_RS05460	COG0019	diaminopimelate decarboxylase activity
AEA01_RS05465	COG4264	IucA IucC family
AEA01_RS05470	COG2814	Major facilitator Superfamily
AEA01_RS05475	COG4264	IucA IucC family
AEA01_RS05485	COG4772	TonB-dependent receptor
AEA01_RS05495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEA01_RS05495	COG4651	solute:proton antiporter activity
AEA01_RS05525	COG0488	(ABC) transporter
AEA01_RS05545	COG0657	acetylesterase activity
AEA01_RS05545	COG2755	lipolytic protein G-D-S-L family
AEA01_RS05565	COG0477	Major facilitator Superfamily
AEA01_RS05630	COG0824	Thioesterase
AEA01_RS05640	COG0848	biopolymer transport protein
AEA01_RS05655	COG2885	chlorophyll binding
AEA01_RS05665	COG0602	queuosine metabolic process
AEA01_RS05710	COG0583	DNA-binding transcription factor activity
AEA01_RS05735	COG1187	pseudouridine synthase activity
AEA01_RS05755	COG0514	ATP-dependent DNA helicase (RecQ)
AEA01_RS05760	COG0783	Belongs to the Dps family
AEA01_RS05765	COG1643	Atp-dependent helicase
AEA01_RS05810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEA01_RS05820	COG1215	transferase activity, transferring glycosyl groups
AEA01_RS05825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEA01_RS05835	COG1199	ATP-dependent helicase activity
AEA01_RS05845	COG1397	ADP-ribosylglycohydrolase
AEA01_RS05855	COG0189	ligase activity
AEA01_RS05870	COG0835	chemotaxis
AEA01_RS05875	COG0840	transmembrane signaling receptor activity
AEA01_RS05880	COG2198	Histidine kinase
AEA01_RS05880	COG0784	Response regulator, receiver
AEA01_RS05880	COG0643	Histidine kinase
AEA01_RS05905	COG1595	DNA-templated transcription, initiation
AEA01_RS05910	COG2304	oxidoreductase activity
AEA01_RS05915	COG1446	asparaginase
AEA01_RS05960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEA01_RS05970	COG3645	SOS response
AEA01_RS05995	COG2963	transposase activity
AEA01_RS06015	COG3537	Alpha-1,2-mannosidase
AEA01_RS06025	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA01_RS06035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AEA01_RS06040	COG1388	LysM domain
AEA01_RS06040	COG3858	chitin binding
AEA01_RS06055	COG0837	glucose binding
AEA01_RS06060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEA01_RS06070	COG0494	nUDIX hydrolase
AEA01_RS06075	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEA01_RS06080	COG3956	TIGRFAM MazG family protein
AEA01_RS06090	COG0330	HflC and HflK could
AEA01_RS06140	COG1309	transcriptional regulator
AEA01_RS06150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AEA01_RS06160	COG0463	Glycosyl transferase, family 2
AEA01_RS06165	COG0517	IMP dehydrogenase activity
AEA01_RS06165	COG0516	GMP reductase activity
AEA01_RS06170	COG2982	Protein involved in outer membrane biogenesis
AEA01_RS06175	COG1272	protein, Hemolysin III
AEA01_RS06190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA01_RS06195	COG0626	cystathionine gamma-synthase activity
AEA01_RS06200	COG0527	aspartate kinase activity
AEA01_RS06200	COG0460	homoserine dehydrogenase
AEA01_RS06210	COG1760	l-serine dehydratase
AEA01_RS06230	COG2353	YceI-like domain
AEA01_RS06250	COG0477	Major facilitator Superfamily
AEA01_RS06285	COG1842	Phage shock protein A
AEA01_RS06310	COG0754	glutathionylspermidine amidase activity
AEA01_RS06315	COG2814	Major facilitator Superfamily
AEA01_RS06390	COG0531	amino acid
AEA01_RS06395	COG2197	response regulator
AEA01_RS06410	COG1113	amino acid transport
AEA01_RS06415	COG1271	oxidase subunit
AEA01_RS06420	COG1294	oxidase, subunit
AEA01_RS06430	COG2239	Acts as a magnesium transporter
AEA01_RS06435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEA01_RS06440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA01_RS06460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA01_RS06475	COG1137	ATPase activity
AEA01_RS06490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AEA01_RS06500	COG0271	Belongs to the BolA IbaG family
AEA01_RS06525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEA01_RS06545	COG0628	permease
AEA01_RS06555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEA01_RS06570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEA01_RS06575	COG1555	photosystem II stabilization
AEA01_RS06620	COG4774	siderophore transport
AEA01_RS06635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEA01_RS06640	COG0719	Fe-S assembly protein
AEA01_RS06645	COG0396	ATPase activity
AEA01_RS06650	COG0719	Fe-S assembly protein
AEA01_RS06665	COG0693	protein deglycase activity
AEA01_RS06700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEA01_RS06730	COG0519	Catalyzes the synthesis of GMP from XMP
AEA01_RS06735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AEA01_RS06755	COG1764	response to oxidative stress
AEA01_RS06765	COG0384	phenazine biosynthesis protein PhzF
AEA01_RS06770	COG0384	phenazine biosynthesis protein PhzF
AEA01_RS06775	COG0527	aspartate kinase activity
AEA01_RS06800	COG0142	geranyltranstransferase activity
AEA01_RS06805	COG0629	single-stranded DNA binding
AEA01_RS06815	COG1401	restriction endodeoxyribonuclease activity
AEA01_RS06825	COG4251	negative regulation of phosphorylation
AEA01_RS06825	COG3706	GGDEF domain
AEA01_RS06825	COG5001	Diguanylate cyclase
AEA01_RS06825	COG2203	Gaf domain
AEA01_RS06830	COG0604	alcohol dehydrogenase
AEA01_RS06835	COG2080	2 iron, 2 sulfur cluster binding
AEA01_RS06840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEA01_RS06845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA01_RS06850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AEA01_RS06855	COG0746	molybdenum cofactor guanylyltransferase activity
AEA01_RS06885	COG2879	small protein
AEA01_RS06890	COG1966	Carbon starvation protein
AEA01_RS06895	COG1741	Belongs to the pirin family
AEA01_RS06910	COG1741	Belongs to the pirin family
AEA01_RS06930	COG3590	peptidase
AEA01_RS06935	COG3039	Transposase
AEA01_RS06940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS06950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEA01_RS06955	COG2202	Pas domain
AEA01_RS06955	COG2199	diguanylate cyclase activity
AEA01_RS06955	COG2200	EAL domain
AEA01_RS06960	COG0835	chemotaxis
AEA01_RS06965	COG0840	transmembrane signaling receptor activity
AEA01_RS06970	COG0643	Histidine kinase
AEA01_RS06970	COG2198	Histidine kinase
AEA01_RS06980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEA01_RS06990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AEA01_RS06995	COG0745	RESPONSE REGULATOR receiver
AEA01_RS07005	COG2205	protein histidine kinase activity
AEA01_RS07010	COG4452	Inner membrane protein CreD
AEA01_RS07045	COG0735	belongs to the Fur family
AEA01_RS07060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA01_RS07070	COG1309	transcriptional regulator
AEA01_RS07075	COG0667	Aldo Keto reductase
AEA01_RS07090	COG2207	Transcriptional regulator
AEA01_RS07110	COG0583	DNA-binding transcription factor activity
AEA01_RS07115	COG2814	Major facilitator Superfamily
AEA01_RS07155	COG1271	oxidase subunit
AEA01_RS07160	COG1294	oxidase, subunit
AEA01_RS07265	COG5001	Diguanylate cyclase
AEA01_RS07265	COG5002	protein histidine kinase activity
AEA01_RS07270	COG1187	pseudouridine synthase activity
AEA01_RS07300	COG0475	glutathione-regulated potassium exporter activity
AEA01_RS07305	COG1132	(ABC) transporter
AEA01_RS07350	COG2155	Conserved Protein
AEA01_RS07360	COG3118	belongs to the thioredoxin family
AEA01_RS07385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEA01_RS07410	COG2968	Membrane
AEA01_RS07425	COG3164	Protein of unknown function
AEA01_RS07435	COG0312	modulator of DNA gyrase
AEA01_RS07445	COG0312	modulator of DNA gyrase
AEA01_RS07460	COG0142	geranyltranstransferase activity
AEA01_RS07475	COG1785	Belongs to the alkaline phosphatase family
AEA01_RS07480	COG1301	dicarboxylic acid transport
AEA01_RS07485	COG4106	trans-aconitate 2-methyltransferase activity
AEA01_RS07510	COG4191	Histidine kinase
AEA01_RS07515	COG3284	Transcriptional regulator
AEA01_RS07550	COG0791	NLP P60 protein
AEA01_RS07555	COG0791	NLP P60 protein
AEA01_RS07560	COG1047	Peptidyl-prolyl cis-trans
AEA01_RS07565	COG2311	Membrane
AEA01_RS07570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA01_RS07575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEA01_RS07595	COG3590	peptidase
AEA01_RS07600	COG3590	peptidase
AEA01_RS07615	COG0489	protein tyrosine kinase activity
AEA01_RS07650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA01_RS07665	COG0494	nUDIX hydrolase
AEA01_RS07675	COG0433	COG0433 Predicted ATPase
AEA01_RS07700	COG2890	protein-(glutamine-N5) methyltransferase activity
AEA01_RS07715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEA01_RS07720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEA01_RS07805	COG4221	oxidoreductase activity
AEA01_RS07825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEA01_RS07845	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AEA01_RS07850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA01_RS07870	COG0839	Belongs to the complex I subunit 6 family
AEA01_RS07890	COG1007	ATP synthesis coupled electron transport
AEA01_RS07905	COG0195	Participates in both transcription termination and antitermination
AEA01_RS07965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEA01_RS07975	COG2095	MarC family integral membrane protein
AEA01_RS07985	COG1611	Belongs to the LOG family
AEA01_RS07990	COG4969	Belongs to the N-Me-Phe pilin family
AEA01_RS08040	COG3505	Type IV secretory pathway VirD4
AEA01_RS08060	COG2948	multi-organism process
AEA01_RS08080	COG3702	type iv secretory pathway
AEA01_RS08100	COG0366	Alpha amylase catalytic
AEA01_RS08105	COG3039	Transposase
AEA01_RS08115	COG1082	Xylose isomerase domain protein TIM barrel
AEA01_RS08145	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEA01_RS08215	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS08220	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS08225	COG2244	polysaccharide biosynthetic process
AEA01_RS08230	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS08255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA01_RS08260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEA01_RS08265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEA01_RS08295	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS08320	COG0322	excinuclease ABC activity
AEA01_RS08345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEA01_RS08355	COG4191	Histidine kinase
AEA01_RS08355	COG0784	Response regulator, receiver
AEA01_RS08375	COG0552	protein localization to endoplasmic reticulum
AEA01_RS08385	COG3938	Belongs to the proline racemase family
AEA01_RS08405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEA01_RS08415	COG0006	proline dipeptidase activity
AEA01_RS08430	COG0531	amino acid
AEA01_RS08460	COG4206	TonB-dependent receptor
AEA01_RS08470	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA01_RS08475	COG1506	peptidase
AEA01_RS08475	COG0823	Involved in the tonB-independent uptake of proteins
AEA01_RS08485	COG4206	TonB-dependent receptor
AEA01_RS08500	COG0326	Molecular chaperone. Has ATPase activity
AEA01_RS08505	COG0742	ribosomal rna small subunit methyltransferase
AEA01_RS08525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEA01_RS08530	COG0405	Gamma-glutamyltransferase
AEA01_RS08535	COG3291	Pkd domain containing protein
AEA01_RS08565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AEA01_RS08585	COG1862	Preprotein translocase
AEA01_RS08595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEA01_RS08615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEA01_RS08615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEA01_RS08620	COG1105	Belongs to the carbohydrate kinase PfkB family
AEA01_RS08625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEA01_RS08625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEA01_RS08630	COG1609	Transcriptional regulator
AEA01_RS08635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEA01_RS08640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA01_RS08650	COG2902	Dehydrogenase
AEA01_RS08655	COG2207	Transcriptional regulator
AEA01_RS08655	COG1609	Transcriptional regulator
AEA01_RS08660	COG1335	isochorismatase
AEA01_RS08665	COG0477	Major facilitator Superfamily
AEA01_RS08675	COG0784	Response regulator, receiver
AEA01_RS08675	COG2205	protein histidine kinase activity
AEA01_RS08675	COG5002	protein histidine kinase activity
AEA01_RS08680	COG2733	membrane
AEA01_RS08690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AEA01_RS08695	COG2223	nitrite transmembrane transporter activity
AEA01_RS08705	COG0243	molybdopterin cofactor binding
AEA01_RS08715	COG0477	Major facilitator Superfamily
AEA01_RS08720	COG2703	oxygen carrier activity
AEA01_RS08730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA01_RS08735	COG0174	glutamine synthetase
AEA01_RS08740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AEA01_RS08775	COG3842	ATPase activity
AEA01_RS08780	COG1176	ABC-type spermidine putrescine transport system, permease component I
AEA01_RS08785	COG1177	transmembrane transport
AEA01_RS08810	COG4535	Mg2 and Co2 transporter CorC
AEA01_RS08830	COG1702	phosphate starvation-inducible protein PhoH
AEA01_RS08850	COG0741	lytic transglycosylase activity
AEA01_RS08855	COG0723	plastoquinol--plastocyanin reductase activity
AEA01_RS08860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AEA01_RS08865	COG2857	Cytochrome c1
AEA01_RS08870	COG0625	glutathione transferase activity
AEA01_RS08875	COG2969	positive regulation of protein catabolic process
AEA01_RS08890	COG1201	RNA secondary structure unwinding
AEA01_RS08900	COG0840	transmembrane signaling receptor activity
AEA01_RS08905	COG0835	chemotaxis
AEA01_RS08955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEA01_RS08970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEA01_RS08975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEA01_RS08975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEA01_RS08985	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEA01_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS09025	COG3300	MHYT domain
AEA01_RS09025	COG5001	Diguanylate cyclase
AEA01_RS09030	COG2081	HI0933 family
AEA01_RS09035	COG4681	YaeQ
AEA01_RS09070	COG0513	Belongs to the DEAD box helicase family
AEA01_RS09075	COG0488	(ABC) transporter
AEA01_RS09090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEA01_RS09095	COG0483	inositol monophosphate 1-phosphatase activity
AEA01_RS09110	COG3300	MHYT domain
AEA01_RS09110	COG5001	Diguanylate cyclase
AEA01_RS09115	COG1509	lysine 2,3-aminomutase activity
AEA01_RS09130	COG0402	S-adenosylhomocysteine deaminase activity
AEA01_RS09155	COG4677	pectinesterase activity
AEA01_RS09175	COG4302	ethanolamine ammonia-lyase activity
AEA01_RS09195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEA01_RS09230	COG2166	iron-sulfur cluster assembly
AEA01_RS09245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEA01_RS09255	COG0137	argininosuccinate synthase activity
AEA01_RS09260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEA01_RS09265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEA01_RS09325	COG1294	oxidase, subunit
AEA01_RS09335	COG4988	ABC transporter
AEA01_RS09340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AEA01_RS09400	COG0436	Aminotransferase
AEA01_RS09420	COG1187	pseudouridine synthase activity
AEA01_RS09425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEA01_RS09430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AEA01_RS09435	COG2350	Protein conserved in bacteria
AEA01_RS09460	COG2182	Extracellular solute-binding protein
AEA01_RS09470	COG0395	ABC-type sugar transport system, permease component
AEA01_RS09495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEA01_RS09500	COG2957	Belongs to the agmatine deiminase family
AEA01_RS09520	COG0539	negative regulation of cytoplasmic translation
AEA01_RS09535	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AEA01_RS09550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AEA01_RS09555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEA01_RS09555	COG0475	glutathione-regulated potassium exporter activity
AEA01_RS09595	COG2197	response regulator
AEA01_RS09610	COG1335	isochorismatase
AEA01_RS09625	COG2814	Major facilitator Superfamily
AEA01_RS09640	COG1914	H( )-stimulated, divalent metal cation uptake system
AEA01_RS09660	COG0668	transmembrane transport
AEA01_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS09690	COG1183	phosphatidylcholine synthase activity
AEA01_RS09700	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEA01_RS09715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEA01_RS09715	COG0723	plastoquinol--plastocyanin reductase activity
AEA01_RS09725	COG2183	response to ionizing radiation
AEA01_RS09730	COG5001	Diguanylate cyclase
AEA01_RS09795	COG0800	Aldolase
AEA01_RS09800	COG0129	dihydroxy-acid dehydratase activity
AEA01_RS09805	COG0363	glucosamine-6-phosphate deaminase activity
AEA01_RS09815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEA01_RS09825	COG0354	folic acid binding
AEA01_RS09835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AEA01_RS09840	COG1053	succinate dehydrogenase
AEA01_RS09850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AEA01_RS09865	COG4591	ABC-type transport system involved in lipoprotein release permease component
AEA01_RS09885	COG0811	peptide transport
AEA01_RS09890	COG0848	biopolymer transport protein
AEA01_RS09910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEA01_RS09925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEA01_RS09945	COG0582	viral genome integration into host DNA
AEA01_RS09985	COG2963	transposase activity
AEA01_RS10020	COG1002	Type II restriction enzyme, methylase subunits
AEA01_RS10025	COG1061	Type III restriction enzyme res subunit
AEA01_RS10030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEA01_RS10045	COG4644	lycopene metabolic process
AEA01_RS10095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEA01_RS10130	COG1530	ribonuclease E activity
AEA01_RS10140	COG0428	transporter
AEA01_RS10245	COG3459	Glycosyltransferase 36 associated
AEA01_RS10255	COG0784	Response regulator, receiver
AEA01_RS10255	COG4191	Histidine kinase
AEA01_RS10285	COG0840	transmembrane signaling receptor activity
AEA01_RS10295	COG1238	metal cluster binding
AEA01_RS10320	COG1733	regulation of RNA biosynthetic process
AEA01_RS10335	COG1999	signal sequence binding
AEA01_RS10350	COG3590	peptidase
AEA01_RS10415	COG5001	Diguanylate cyclase
AEA01_RS10425	COG2201	protein-glutamate methylesterase activity
AEA01_RS10430	COG3685	Protein conserved in bacteria
AEA01_RS10445	COG0579	oxidoreductase
AEA01_RS10455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEA01_RS10465	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AEA01_RS10485	COG0243	molybdopterin cofactor binding
AEA01_RS10495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AEA01_RS10500	COG2223	nitrite transmembrane transporter activity
AEA01_RS10505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AEA01_RS10515	COG1648	precorrin-2 dehydrogenase activity
AEA01_RS10515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEA01_RS10525	COG0746	molybdenum cofactor guanylyltransferase activity
AEA01_RS10530	COG0303	'Molybdopterin
AEA01_RS10540	COG0708	Exodeoxyribonuclease III
AEA01_RS10565	COG2124	cytochrome p450
AEA01_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS10585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AEA01_RS10600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_RS10635	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEA01_RS10635	COG1024	Enoyl-CoA hydratase
AEA01_RS10640	COG0183	Belongs to the thiolase family
AEA01_RS10645	COG0038	chloride channel
AEA01_RS10650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEA01_RS10670	COG1674	ftsk spoiiie
AEA01_RS10675	COG0492	ferredoxin-NADP+ reductase activity
AEA01_RS10695	COG0542	response to heat
AEA01_RS10715	COG2915	High frequency lysogenization protein hflD homolog
AEA01_RS10750	COG4191	Histidine kinase
AEA01_RS10770	COG0835	chemotaxis
AEA01_RS10770	COG0784	Response regulator, receiver
AEA01_RS10780	COG1558	bacterial-type flagellum-dependent cell motility
AEA01_RS10785	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AEA01_RS10795	COG4787	bacterial-type flagellum-dependent cell motility
AEA01_RS10815	COG3951	Flagellar rod assembly protein muramidase FlgJ
AEA01_RS10815	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEA01_RS10825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEA01_RS10830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEA01_RS10835	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AEA01_RS10865	COG2201	protein-glutamate methylesterase activity
AEA01_RS10895	COG1216	Glycosyl transferase, family 2
AEA01_RS10895	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS10900	COG1677	Flagellar hook-basal body complex protein FliE
AEA01_RS10965	COG1987	bacterial-type flagellum assembly
AEA01_RS10970	COG1684	flagellar biosynthetic protein fliR
AEA01_RS11025	COG0784	Response regulator, receiver
AEA01_RS11025	COG2198	Histidine kinase
AEA01_RS11025	COG0643	Histidine kinase
AEA01_RS11070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AEA01_RS11075	COG1360	Flagellar Motor Protein
AEA01_RS11080	COG1192	Involved in chromosome partitioning
AEA01_RS11085	COG0835	chemotaxis
AEA01_RS11095	COG0745	RESPONSE REGULATOR receiver
AEA01_RS11105	COG0840	transmembrane signaling receptor activity
AEA01_RS11125	COG0840	transmembrane signaling receptor activity
AEA01_RS11130	COG0840	transmembrane signaling receptor activity
AEA01_RS11135	COG0840	transmembrane signaling receptor activity
AEA01_RS11150	COG0835	chemotaxis
AEA01_RS11160	COG0840	transmembrane signaling receptor activity
AEA01_RS11185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEA01_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
AEA01_RS11220	COG1024	Enoyl-CoA hydratase
AEA01_RS11225	COG2205	protein histidine kinase activity
AEA01_RS11225	COG0784	Response regulator, receiver
AEA01_RS11225	COG2198	Histidine kinase
AEA01_RS11230	COG2198	Histidine kinase
AEA01_RS11230	COG2205	protein histidine kinase activity
AEA01_RS11230	COG0784	Response regulator, receiver
AEA01_RS11245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEA01_RS11250	COG3279	Response regulator of the LytR AlgR family
AEA01_RS11275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEA01_RS11285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA01_RS11290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AEA01_RS11300	COG0505	Belongs to the CarA family
AEA01_RS11310	COG2258	MOSC domain
AEA01_RS11315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEA01_RS11340	COG1024	Enoyl-CoA hydratase
AEA01_RS11375	COG0277	FAD linked oxidase domain protein
AEA01_RS11380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEA01_RS11395	COG0531	amino acid
AEA01_RS11400	COG0531	amino acid
AEA01_RS11430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEA01_RS11430	COG0140	phosphoribosyl-ATP diphosphatase activity
AEA01_RS11450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AEA01_RS11450	COG0131	Imidazoleglycerol-phosphate dehydratase
AEA01_RS11480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEA01_RS11490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AEA01_RS11530	COG2963	transposase activity
AEA01_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
AEA01_RS11645	COG0697	spore germination
AEA01_RS11650	COG1794	racemase activity, acting on amino acids and derivatives
AEA01_RS11660	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS11675	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AEA01_RS11680	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AEA01_RS11685	COG2203	Gaf domain
AEA01_RS11685	COG3706	GGDEF domain
AEA01_RS11685	COG4251	negative regulation of phosphorylation
AEA01_RS11685	COG5001	Diguanylate cyclase
AEA01_RS11695	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA01_RS11755	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEA01_RS11775	COG0477	Major facilitator Superfamily
AEA01_RS11785	COG1070	Carbohydrate kinase
AEA01_RS11795	COG1501	Belongs to the glycosyl hydrolase 31 family
AEA01_RS11830	COG0800	Aldolase
AEA01_RS11845	COG3734	2-keto-3-deoxy-galactonokinase
AEA01_RS11850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AEA01_RS11860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEA01_RS11875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEA01_RS11880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AEA01_RS11890	COG0352	thiamine-phosphate diphosphorylase activity
AEA01_RS11890	COG0351	phosphomethylpyrimidine kinase
AEA01_RS11915	COG0583	DNA-binding transcription factor activity
AEA01_RS11920	COG1741	Belongs to the pirin family
AEA01_RS11955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEA01_RS11970	COG4771	TonB-dependent receptor
AEA01_RS11975	COG1546	Belongs to the CinA family
AEA01_RS11980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEA01_RS11995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEA01_RS12000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEA01_RS12010	COG1534	Rna-binding protein
AEA01_RS12025	COG1238	metal cluster binding
AEA01_RS12040	COG2840	Smr protein MutS2
AEA01_RS12095	COG2134	cdp-diacylglycerol pyrophosphatase
AEA01_RS12120	COG1253	flavin adenine dinucleotide binding
AEA01_RS12135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AEA01_RS12140	COG0477	Major facilitator Superfamily
AEA01_RS12145	COG1132	(ABC) transporter
AEA01_RS12165	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS12170	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS12175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEA01_RS12205	COG2244	polysaccharide biosynthetic process
AEA01_RS12220	COG3038	cytochrome b561
AEA01_RS12255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEA01_RS12275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA01_RS12290	COG0784	Response regulator, receiver
AEA01_RS12290	COG4191	Histidine kinase
AEA01_RS12295	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AEA01_RS12340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AEA01_RS12365	COG2963	transposase activity
AEA01_RS12370	COG2801	Transposase and inactivated derivatives
AEA01_RS12375	COG2963	transposase activity
AEA01_RS12390	COG2963	transposase activity
AEA01_RS12400	COG3039	Transposase
AEA01_RS12410	COG2963	transposase activity
AEA01_RS12415	COG2963	transposase activity
AEA01_RS12420	COG2801	Transposase and inactivated derivatives
AEA01_RS12425	COG2801	Transposase and inactivated derivatives
AEA01_RS12430	COG2963	transposase activity
AEA01_RS12440	COG0583	DNA-binding transcription factor activity
AEA01_RS12455	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AEA01_RS12465	COG1605	Chorismate mutase
AEA01_RS12465	COG0077	Prephenate dehydratase
AEA01_RS12475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEA01_RS12530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AEA01_RS12540	COG4993	Dehydrogenase
AEA01_RS12560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AEA01_RS12570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEA01_RS12605	COG0316	Belongs to the HesB IscA family
AEA01_RS12635	COG0288	reversible hydration of carbon dioxide
AEA01_RS12660	COG2925	Exonuclease
AEA01_RS12675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AEA01_RS12695	COG0488	(ABC) transporter
AEA01_RS12700	COG2264	protein methyltransferase activity
AEA01_RS12735	COG0494	nUDIX hydrolase
AEA01_RS12745	COG1024	Enoyl-CoA hydratase
AEA01_RS12755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEA01_RS12760	COG0659	secondary active sulfate transmembrane transporter activity
AEA01_RS12785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEA01_RS12790	COG0573	inorganic phosphate transmembrane transporter activity
AEA01_RS12795	COG0581	inorganic phosphate transmembrane transporter activity
AEA01_RS12805	COG0704	Plays a role in the regulation of phosphate uptake
AEA01_RS12825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEA01_RS12835	COG0557	exoribonuclease II activity
AEA01_RS12850	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS12855	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS12860	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS12865	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS12870	COG2226	methyltransferase
AEA01_RS12875	COG0646	methionine synthase
AEA01_RS12875	COG1410	methionine synthase
AEA01_RS12880	COG1410	methionine synthase
AEA01_RS12880	COG0646	methionine synthase
AEA01_RS12890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEA01_RS12900	COG1609	Transcriptional regulator
AEA01_RS12935	COG0386	Belongs to the glutathione peroxidase family
AEA01_RS12940	COG1725	Transcriptional regulator
AEA01_RS12945	COG1131	(ABC) transporter
AEA01_RS12975	COG1253	flavin adenine dinucleotide binding
AEA01_RS12985	COG2850	peptidyl-arginine hydroxylation
AEA01_RS13020	COG1132	(ABC) transporter
AEA01_RS13025	COG0583	DNA-binding transcription factor activity
AEA01_RS13030	COG2274	protein secretion by the type I secretion system
AEA01_RS13055	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AEA01_RS13070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEA01_RS13075	COG1420	regulation of RNA biosynthetic process
AEA01_RS13080	COG0497	DNA recombination
AEA01_RS13090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_RS13110	COG1404	Belongs to the peptidase S8 family
AEA01_RS13125	COG2963	transposase activity
AEA01_RS13155	COG3706	GGDEF domain
AEA01_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS13185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA01_RS13195	COG0583	DNA-binding transcription factor activity
AEA01_RS13200	COG2885	chlorophyll binding
AEA01_RS13205	COG0415	Belongs to the DNA photolyase family
AEA01_RS13210	COG0305	Participates in initiation and elongation during chromosome replication
AEA01_RS13220	COG0367	asparagine synthase
AEA01_RS13250	COG0084	hydrolase, TatD family'
AEA01_RS13255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AEA01_RS13315	COG0386	Belongs to the glutathione peroxidase family
AEA01_RS13320	COG0339	signal peptide processing
AEA01_RS13350	COG3104	oligopeptide transport
AEA01_RS13380	COG2814	Major facilitator Superfamily
AEA01_RS13385	COG1566	PFAM secretion protein HlyD family protein
AEA01_RS13425	COG4774	siderophore transport
AEA01_RS13435	COG0367	asparagine synthase
AEA01_RS13450	COG1393	Belongs to the ArsC family
AEA01_RS13525	COG0528	UMP kinase activity
AEA01_RS13535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AEA01_RS13540	COG0575	Belongs to the CDS family
AEA01_RS13550	COG0750	zinc metalloprotease
AEA01_RS13605	COG1981	membrane
AEA01_RS13625	COG1695	Transcriptional regulator
AEA01_RS13655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AEA01_RS13665	COG2040	homocysteine
AEA01_RS13670	COG0833	amino acid
AEA01_RS13680	COG0346	lactoylglutathione lyase activity
AEA01_RS13705	COG2878	Part of a membrane complex involved in electron transport
AEA01_RS13720	COG1595	DNA-templated transcription, initiation
AEA01_RS13745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEA01_RS13760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEA01_RS13765	COG0251	oxidation-reduction process
AEA01_RS13775	COG0392	lysyltransferase activity
AEA01_RS13775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AEA01_RS13815	COG2814	Major facilitator Superfamily
AEA01_RS13820	COG1902	pentaerythritol trinitrate reductase activity
AEA01_RS13835	COG2824	Alkylphosphonate utilization operon protein PhnA
AEA01_RS13845	COG1047	Peptidyl-prolyl cis-trans
AEA01_RS13880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEA01_RS13890	COG5487	UPF0391 membrane protein
AEA01_RS13895	COG1451	nucleotide metabolic process
AEA01_RS13915	COG0183	Belongs to the thiolase family
AEA01_RS13945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEA01_RS13945	COG1793	dna ligase
AEA01_RS13955	COG1793	dna ligase
AEA01_RS13960	COG1201	RNA secondary structure unwinding
AEA01_RS13970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA01_RS13975	COG1278	Cold shock
AEA01_RS13980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEA01_RS13985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AEA01_RS13995	COG3046	protein related to deoxyribodipyrimidine photolyase
AEA01_RS14000	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AEA01_RS14005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AEA01_RS14010	COG2954	triphosphatase activity
AEA01_RS14060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEA01_RS14095	COG1024	Enoyl-CoA hydratase
AEA01_RS14100	COG1960	acyl-CoA dehydrogenase activity
AEA01_RS14110	COG3800	Transcriptional regulator
AEA01_RS14110	COG1396	sequence-specific DNA binding
AEA01_RS14120	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AEA01_RS14125	COG3250	beta-galactosidase activity
AEA01_RS14260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AEA01_RS14315	COG5297	Belongs to the glycosyl hydrolase family 6
AEA01_RS14335	COG1309	transcriptional regulator
AEA01_RS14340	COG0436	Aminotransferase
AEA01_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS14350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEA01_RS14365	COG3483	tryptophan 2,3-dioxygenase activity
AEA01_RS14380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEA01_RS14400	COG0534	Mate efflux family protein
AEA01_RS14430	COG2070	2-Nitropropane dioxygenase
AEA01_RS14445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEA01_RS14450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEA01_RS14460	COG3534	alpha-L-arabinofuranosidase
AEA01_RS14485	COG4191	Histidine kinase
AEA01_RS14485	COG0784	Response regulator, receiver
AEA01_RS14490	COG2205	protein histidine kinase activity
AEA01_RS14490	COG3437	response regulator, receiver
AEA01_RS14490	COG3850	Histidine kinase
AEA01_RS14490	COG4999	Histidine kinase
AEA01_RS14495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEA01_RS14505	COG2205	protein histidine kinase activity
AEA01_RS14510	COG5507	3-demethylubiquinone-9 3-methyltransferase
AEA01_RS14520	COG4771	TonB-dependent receptor
AEA01_RS14555	COG2172	sigma factor antagonist activity
AEA01_RS14560	COG1366	Belongs to the anti-sigma-factor antagonist family
AEA01_RS14565	COG1366	Belongs to the anti-sigma-factor antagonist family
AEA01_RS14570	COG1902	pentaerythritol trinitrate reductase activity
AEA01_RS14580	COG0326	Molecular chaperone. Has ATPase activity
AEA01_RS14585	COG2207	Transcriptional regulator
AEA01_RS14600	COG3152	Membrane
AEA01_RS14615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AEA01_RS14620	COG1845	cytochrome c oxidase, subunit III
AEA01_RS14625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEA01_RS14655	COG0196	riboflavin kinase activity
AEA01_RS14685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEA01_RS14690	COG0824	Thioesterase
AEA01_RS14695	COG1024	Enoyl-CoA hydratase
AEA01_RS14700	COG1946	Acyl-CoA thioesterase
AEA01_RS14710	COG1595	DNA-templated transcription, initiation
AEA01_RS14775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AEA01_RS14800	COG2197	response regulator
AEA01_RS14805	COG4585	Histidine kinase
AEA01_RS14815	COG0850	regulation of cytokinetic process
AEA01_RS14820	COG2894	cell division
AEA01_RS14835	COG5002	protein histidine kinase activity
AEA01_RS14840	COG0745	RESPONSE REGULATOR receiver
AEA01_RS14855	COG2194	sulfuric ester hydrolase activity
AEA01_RS14875	COG2814	Major facilitator Superfamily
AEA01_RS14900	COG0656	L-ascorbic acid biosynthetic process
AEA01_RS14905	COG0753	catalase activity
AEA01_RS14915	COG2207	Transcriptional regulator
AEA01_RS14915	COG1917	Cupin 2, conserved barrel domain protein
AEA01_RS14930	COG0823	Involved in the tonB-independent uptake of proteins
AEA01_RS14930	COG1506	peptidase
AEA01_RS14940	COG1297	OPT oligopeptide transporter protein
AEA01_RS14965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEA01_RS14990	COG2080	2 iron, 2 sulfur cluster binding
AEA01_RS14995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEA01_RS15000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA01_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS15050	COG3537	Alpha-1,2-mannosidase
AEA01_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS15065	COG3387	PFAM Glycoside hydrolase 15-related
AEA01_RS15080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEA01_RS15115	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEA01_RS15120	COG0732	type I restriction modification DNA specificity domain
AEA01_RS15130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AEA01_RS15180	COG0308	aminopeptidase N
AEA01_RS15195	COG0330	HflC and HflK could
AEA01_RS15200	COG0330	HflC and HflK could
AEA01_RS15220	COG0678	peroxiredoxin activity
AEA01_RS15230	COG4953	penicillin-binding protein 1C
AEA01_RS15255	COG2373	Large extracellular alpha-helical protein
AEA01_RS15280	COG3609	addiction module antidote protein, CC2985 family
AEA01_RS15300	COG3829	transcription factor binding
AEA01_RS15340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AEA01_RS15345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEA01_RS15360	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS15365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AEA01_RS15370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEA01_RS15380	COG1399	metal-binding, possibly nucleic acid-binding protein
AEA01_RS15410	COG0714	Associated with various cellular activities
AEA01_RS15430	COG0537	adenosine 5'-monophosphoramidase activity
AEA01_RS15455	COG0314	molybdopterin synthase activity
AEA01_RS15460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AEA01_RS15480	COG1234	tRNA 3'-trailer cleavage
AEA01_RS15490	COG0859	PFAM glycosyl transferase family 9
AEA01_RS15505	COG0631	protein serine/threonine phosphatase activity
AEA01_RS15510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEA01_RS15615	COG0473	3-isopropylmalate dehydrogenase activity
AEA01_RS15630	COG4783	chaperone-mediated protein folding
AEA01_RS15645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEA01_RS15655	COG0438	transferase activity, transferring glycosyl groups
AEA01_RS15660	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS15665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEA01_RS15675	COG3291	Pkd domain containing protein
AEA01_RS15680	COG2833	Protein of unknown function (DUF455)
AEA01_RS15700	COG0285	dihydrofolate synthase activity
AEA01_RS15715	COG0406	alpha-ribazole phosphatase activity
AEA01_RS15740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEA01_RS15745	COG4208	sulfate ABC transporter
AEA01_RS15750	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AEA01_RS15755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AEA01_RS15790	COG1902	pentaerythritol trinitrate reductase activity
AEA01_RS15790	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEA01_RS15815	COG0625	glutathione transferase activity
AEA01_RS15825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEA01_RS15830	COG1217	gtp-binding protein TYPA
AEA01_RS15840	COG0154	amidase activity
AEA01_RS15850	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AEA01_RS15885	COG0201	protein transport
AEA01_RS16045	COG0250	Participates in transcription elongation, termination and antitermination
AEA01_RS16080	COG0012	GTP binding
AEA01_RS16085	COG0193	aminoacyl-tRNA hydrolase activity
AEA01_RS16095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEA01_RS16135	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEA01_RS16155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEA01_RS16185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEA01_RS16190	COG1404	Belongs to the peptidase S8 family
AEA01_RS16195	COG1404	Belongs to the peptidase S8 family
AEA01_RS16200	COG1404	Belongs to the peptidase S8 family
AEA01_RS16205	COG1404	Belongs to the peptidase S8 family
AEA01_RS16210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEA01_RS16260	COG0778	Nitroreductase
AEA01_RS16265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEA01_RS16265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEA01_RS16285	COG2890	protein-(glutamine-N5) methyltransferase activity
AEA01_RS16295	COG3634	alkyl hydroperoxide reductase activity
AEA01_RS16300	COG0583	DNA-binding transcription factor activity
AEA01_RS16305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEA01_RS16330	COG2197	response regulator
AEA01_RS16335	COG0784	Response regulator, receiver
AEA01_RS16335	COG2205	protein histidine kinase activity
AEA01_RS16335	COG5002	protein histidine kinase activity
AEA01_RS16365	COG0697	spore germination
AEA01_RS16395	COG3386	PFAM SMP-30 Gluconolaconase
AEA01_RS16415	COG1024	Enoyl-CoA hydratase
AEA01_RS16425	COG0318	PFAM AMP-dependent synthetase and ligase
AEA01_RS16430	COG0583	DNA-binding transcription factor activity
AEA01_RS16435	COG3384	dioxygenase
AEA01_RS16465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA01_RS16470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEA01_RS16480	COG2096	Adenosyltransferase
AEA01_RS16485	COG0123	including yeast histone deacetylase and acetoin utilization protein
AEA01_RS16515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AEA01_RS16550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AEA01_RS16560	COG0642	Histidine kinase
AEA01_RS16575	COG4181	ATPase activity
AEA01_RS16585	COG2175	clavaminate synthase activity
AEA01_RS16595	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AEA01_RS16620	COG4771	TonB-dependent receptor
AEA01_RS16630	COG0667	Aldo Keto reductase
AEA01_RS16635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AEA01_RS16645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AEA01_RS16730	COG0366	Alpha amylase catalytic
AEA01_RS16760	COG3321	synthase
AEA01_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS16760	COG0604	alcohol dehydrogenase
AEA01_RS16775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEA01_RS16790	COG0494	nUDIX hydrolase
AEA01_RS16805	COG0739	heme binding
AEA01_RS16830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEA01_RS16835	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEA01_RS16860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEA01_RS16875	COG3116	cell division
AEA01_RS16920	COG1988	membrane-bound metal-dependent
AEA01_RS16925	COG0277	FAD linked oxidase domain protein
AEA01_RS16935	COG0745	RESPONSE REGULATOR receiver
AEA01_RS16940	COG2205	protein histidine kinase activity
AEA01_RS16950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AEA01_RS16955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEA01_RS16970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEA01_RS17000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEA01_RS17000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEA01_RS17025	COG0488	(ABC) transporter
AEA01_RS17030	COG0242	peptide deformylase activity
AEA01_RS17035	COG1393	Belongs to the ArsC family
AEA01_RS17050	COG0457	Tetratricopeptide repeat
AEA01_RS17100	COG2188	Transcriptional regulator
AEA01_RS17110	COG1450	Type ii and iii secretion system protein
AEA01_RS17125	COG3166	PFAM Fimbrial assembly family protein
AEA01_RS17130	COG3156	type II secretion system protein K
AEA01_RS17135	COG4795	General secretion pathway protein
AEA01_RS17140	COG2165	general secretion pathway protein
AEA01_RS17145	COG4970	Tfp pilus assembly protein FimT
AEA01_RS17150	COG2165	general secretion pathway protein
AEA01_RS17155	COG1459	type II secretion system
AEA01_RS17160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AEA01_RS17165	COG1404	Belongs to the peptidase S8 family
AEA01_RS17180	COG0047	phosphoribosylformylglycinamidine synthase activity
AEA01_RS17180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEA01_RS17185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEA01_RS17190	COG4974	Belongs to the 'phage' integrase family
AEA01_RS17200	COG0795	lipopolysaccharide-transporting ATPase activity
AEA01_RS17250	COG1183	phosphatidylcholine synthase activity
AEA01_RS17275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEA01_RS17280	COG1127	ABC transporter
AEA01_RS17285	COG3218	ABC-type transport auxiliary lipoprotein component
AEA01_RS17285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEA01_RS17350	COG2086	electron transfer activity
AEA01_RS17360	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AEA01_RS17360	COG0662	Cupin 2, conserved barrel domain protein
AEA01_RS17365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEA01_RS17370	COG0463	Glycosyl transferase, family 2
AEA01_RS17380	COG2963	transposase activity
AEA01_RS17390	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AEA01_RS17415	COG0626	cystathionine gamma-synthase activity
AEA01_RS17445	COG0625	glutathione transferase activity
AEA01_RS17455	COG0513	Belongs to the DEAD box helicase family
AEA01_RS17460	COG0720	synthase
AEA01_RS17475	COG1956	GAF domain-containing protein
AEA01_RS17505	COG0339	signal peptide processing
AEA01_RS17510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEA01_RS17555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEA01_RS17565	COG1136	(ABC) transporter
AEA01_RS17575	COG1136	(ABC) transporter
AEA01_RS17575	COG0577	efflux transmembrane transporter activity
AEA01_RS17595	COG2963	transposase activity
AEA01_RS17600	COG2801	Transposase and inactivated derivatives
AEA01_RS17660	COG0356	it plays a direct role in the translocation of protons across the membrane
AEA01_RS17675	COG1228	amidohydrolase
AEA01_RS17680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEA01_RS17735	COG2011	ABC-type metal ion transport system permease component
AEA01_RS17745	COG0697	spore germination
AEA01_RS17775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEA01_RS17780	COG1187	pseudouridine synthase activity
AEA01_RS17785	COG2813	Specifically methylates the guanine in position
AEA01_RS17805	COG5002	protein histidine kinase activity
AEA01_RS17885	COG0842	Transport permease protein
AEA01_RS17890	COG1131	(ABC) transporter
AEA01_RS17895	COG0025	NhaP-type Na H and K H
AEA01_RS17900	COG3795	YCII-related domain
AEA01_RS17905	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEA01_RS17910	COG1573	uracil-dna glycosylase
AEA01_RS17920	COG3384	dioxygenase
AEA01_RS17925	COG0583	DNA-binding transcription factor activity
AEA01_RS17935	COG0667	Aldo Keto reductase
AEA01_RS17945	COG3590	peptidase
AEA01_RS17960	COG0531	amino acid
AEA01_RS17975	COG2972	Histidine kinase
AEA01_RS17990	COG1335	isochorismatase
AEA01_RS17995	COG3685	Protein conserved in bacteria
AEA01_RS18000	COG3685	Protein conserved in bacteria
AEA01_RS18005	COG3546	catalase activity
AEA01_RS18035	COG2204	response regulator
AEA01_RS18045	COG1271	oxidase subunit
AEA01_RS18050	COG1294	oxidase, subunit
AEA01_RS18065	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS18070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEA01_RS18090	COG1132	(ABC) transporter
AEA01_RS18105	COG1063	alcohol dehydrogenase
AEA01_RS18130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEA01_RS18185	COG0251	oxidation-reduction process
AEA01_RS18205	COG0667	Aldo Keto reductase
AEA01_RS18210	COG0583	DNA-binding transcription factor activity
AEA01_RS18230	COG5001	Diguanylate cyclase
AEA01_RS18230	COG4251	negative regulation of phosphorylation
AEA01_RS18230	COG3706	GGDEF domain
AEA01_RS18230	COG2203	Gaf domain
AEA01_RS18245	COG2963	transposase activity
AEA01_RS18265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEA01_RS18275	COG1560	Kdo2-lipid A biosynthetic process
AEA01_RS18285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEA01_RS18320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEA01_RS18320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEA01_RS18330	COG0242	peptide deformylase activity
AEA01_RS18335	COG1652	LysM domain
AEA01_RS18340	COG0758	DNA mediated transformation
AEA01_RS18360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEA01_RS18360	COG1754	DNA topoisomerase type I activity
AEA01_RS18380	COG5001	Diguanylate cyclase
AEA01_RS18380	COG2203	Gaf domain
AEA01_RS18380	COG3706	GGDEF domain
AEA01_RS18380	COG4251	negative regulation of phosphorylation
AEA01_RS18385	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS18395	COG0616	signal peptide processing
AEA01_RS18400	COG0534	Mate efflux family protein
AEA01_RS18415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEA01_RS18420	COG0625	glutathione transferase activity
AEA01_RS18435	COG1252	NADH dehydrogenase
AEA01_RS18440	COG2860	membrane
AEA01_RS18445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEA01_RS18455	COG2201	protein-glutamate methylesterase activity
AEA01_RS18460	COG2177	Part of the ABC transporter FtsEX involved in
AEA01_RS18465	COG2884	Cell division ATP-binding protein ftsE
AEA01_RS18475	COG3118	belongs to the thioredoxin family
AEA01_RS18480	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AEA01_RS18525	COG1473	amidohydrolase
AEA01_RS18530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEA01_RS18560	COG4941	Belongs to the sigma-70 factor family
AEA01_RS18565	COG5383	Protein conserved in bacteria
AEA01_RS18605	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AEA01_RS18610	COG3501	Rhs element vgr protein
AEA01_RS18610	COG3409	Peptidoglycan-binding domain 1 protein
AEA01_RS18625	COG3023	N-Acetylmuramoyl-L-alanine amidase
AEA01_RS18635	COG4948	Mandelate Racemase Muconate Lactonizing
AEA01_RS18645	COG0531	amino acid
AEA01_RS18660	COG4682	membrane
AEA01_RS18665	COG2133	pyrroloquinoline quinone binding
AEA01_RS18675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AEA01_RS18690	COG1610	YqeY-like protein
AEA01_RS18695	COG1295	ribonuclease BN
AEA01_RS18700	COG0358	DNA primase activity
AEA01_RS18750	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AEA01_RS18765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEA01_RS18785	COG2801	Transposase and inactivated derivatives
AEA01_RS18790	COG2963	transposase activity
AEA01_RS18795	COG2801	Transposase and inactivated derivatives
AEA01_RS18800	COG2963	transposase activity
AEA01_RS18810	COG2801	Transposase and inactivated derivatives
AEA01_RS18815	COG2963	transposase activity
AEA01_RS18825	COG3039	Transposase
AEA01_RS18865	COG0739	heme binding
AEA01_RS18885	COG0708	Exodeoxyribonuclease III
AEA01_RS18900	COG1192	Involved in chromosome partitioning
AEA01_RS18905	COG1475	DNA binding
AEA01_RS18925	COG0463	Glycosyl transferase, family 2
AEA01_RS18950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEA01_RS18975	COG4221	oxidoreductase activity
AEA01_RS18980	COG2755	lipolytic protein G-D-S-L family
AEA01_RS18980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEA01_RS18995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AEA01_RS19000	COG1166	arginine decarboxylase activity
AEA01_RS19025	COG2960	long-chain fatty acid transporting porin activity
AEA01_RS19030	COG0606	chelatase, subunit chli
AEA01_RS19045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AEA01_RS19080	COG1690	Belongs to the RtcB family
AEA01_RS19115	COG1090	epimerase
AEA01_RS19135	COG0642	Histidine kinase
AEA01_RS19155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEA01_RS19180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEA01_RS19185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEA01_RS19210	COG2197	response regulator
AEA01_RS19215	COG4585	Histidine kinase
AEA01_RS19225	COG1136	(ABC) transporter
AEA01_RS19250	COG0697	spore germination
AEA01_RS19280	COG0180	Tryptophanyl-tRNA synthetase
AEA01_RS19285	COG3237	CsbD-like
AEA01_RS19360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AEA01_RS19360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AEA01_RS19370	COG3228	Belongs to the MtfA family
AEA01_RS19400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AEA01_RS19425	COG1199	ATP-dependent helicase activity
AEA01_RS19480	COG0625	glutathione transferase activity
AEA01_RS19515	COG4555	ABC transporter
AEA01_RS19525	COG1476	TRANSCRIPTIONal
AEA01_RS19540	COG1230	cation diffusion facilitator family transporter
AEA01_RS19550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AEA01_RS19555	COG1131	(ABC) transporter
AEA01_RS19560	COG0842	Transport permease protein
AEA01_RS19570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AEA01_RS19580	COG1607	acyl-coa hydrolase
AEA01_RS19595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEA01_RS19600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEA01_RS19610	COG0045	succinate-CoA ligase (ADP-forming) activity
AEA01_RS19610	COG1042	CoA-binding domain protein
AEA01_RS19610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEA01_RS19615	COG2239	Acts as a magnesium transporter
AEA01_RS19630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEA01_RS19635	COG3387	PFAM Glycoside hydrolase 15-related
AEA01_RS19650	COG3100	YcgL domain-containing protein
AEA01_RS19655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEA01_RS19665	COG0463	Glycosyl transferase, family 2
AEA01_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS19710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEA01_RS19725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEA01_RS19800	COG0210	DNA helicase
AEA01_RS19810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS19815	COG0583	DNA-binding transcription factor activity
AEA01_RS19820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AEA01_RS19830	COG2159	amidohydrolase
AEA01_RS19890	COG2091	lysine biosynthetic process via aminoadipic acid
AEA01_RS19950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEA01_RS19960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEA01_RS19965	COG3162	membrane
AEA01_RS20000	COG3507	Belongs to the glycosyl hydrolase 43 family
AEA01_RS20015	COG1028	Short-chain dehydrogenase reductase Sdr
AEA01_RS20020	COG0179	Fumarylacetoacetate (FAA) hydrolase
AEA01_RS20025	COG4948	Mandelate Racemase Muconate Lactonizing
AEA01_RS20030	COG3254	rhamnose metabolic process
AEA01_RS20035	COG0738	Major facilitator superfamily
AEA01_RS20040	COG1414	Transcriptional regulator
AEA01_RS20060	COG0784	Response regulator, receiver
AEA01_RS20060	COG2205	protein histidine kinase activity
AEA01_RS20065	COG3459	Glycosyltransferase 36 associated
AEA01_RS20070	COG2211	Major facilitator Superfamily
AEA01_RS20075	COG3265	gluconokinase activity
AEA01_RS20080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_RS20100	COG2911	Protein conserved in bacteria
AEA01_RS20105	COG0729	surface antigen
AEA01_RS20120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AEA01_RS20125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEA01_RS20125	COG0519	Catalyzes the synthesis of GMP from XMP
AEA01_RS20135	COG0805	protein transport
AEA01_RS20155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEA01_RS20200	COG3661	Belongs to the glycosyl hydrolase 67 family
AEA01_RS20220	COG1472	Belongs to the glycosyl hydrolase 3 family
AEA01_RS20225	COG0246	Mannitol dehydrogenase
AEA01_RS20260	COG3386	PFAM SMP-30 Gluconolaconase
AEA01_RS20275	COG3250	beta-galactosidase activity
AEA01_RS20285	COG3693	PFAM glycoside hydrolase, family 10
AEA01_RS20300	COG2211	Major facilitator Superfamily
AEA01_RS20370	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AEA01_RS20390	COG0210	DNA helicase
AEA01_RS20395	COG2963	transposase activity
AEA01_RS20400	COG2801	Transposase and inactivated derivatives
AEA01_RS20455	COG3135	benzoate transporter
AEA01_RS20475	COG0676	glucose-6-phosphate 1-epimerase activity
AEA01_RS20495	COG0730	response to heat
AEA01_RS20520	COG0302	gtp cyclohydrolase
AEA01_RS20535	COG1566	PFAM secretion protein HlyD family protein
AEA01_RS20545	COG1289	transmembrane transporter activity
AEA01_RS20550	COG0477	Major facilitator Superfamily
AEA01_RS20560	COG0583	DNA-binding transcription factor activity
AEA01_RS20565	COG4221	oxidoreductase activity
AEA01_RS20570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEA01_RS20610	COG3039	Transposase
AEA01_RS20645	COG0564	pseudouridine synthase activity
AEA01_RS20660	COG1192	Involved in chromosome partitioning
AEA01_RS20695	COG1074	ATP-dependent DNA helicase activity
AEA01_RS20700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AEA01_RS20735	COG1127	ABC transporter
AEA01_RS20740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEA01_RS20745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEA01_RS20760	COG2853	Lipoprotein
AEA01_RS20765	COG0386	Belongs to the glutathione peroxidase family
AEA01_RS20775	COG1322	Protein conserved in bacteria
AEA01_RS20780	COG0604	alcohol dehydrogenase
AEA01_RS20785	COG0583	DNA-binding transcription factor activity
AEA01_RS20800	COG0531	amino acid
AEA01_RS20810	COG4206	TonB-dependent receptor
AEA01_RS20820	COG3706	GGDEF domain
AEA01_RS20825	COG3835	regulator
AEA01_RS20830	COG1929	Belongs to the glycerate kinase type-1 family
AEA01_RS20835	COG2271	Major facilitator Superfamily
AEA01_RS20855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AEA01_RS20860	COG0861	Integral membrane protein TerC family
AEA01_RS20875	COG0584	glycerophosphoryl diester phosphodiesterase
AEA01_RS20885	COG0671	phosphoesterase, PA-phosphatase related
AEA01_RS20900	COG0726	polysaccharide deacetylase
AEA01_RS20905	COG0706	membrane insertase activity
