locus-tag	class	description
XC_RS00020	COG0187	DNA topoisomerase II activity
XC_RS00030	COG0501	Belongs to the peptidase M48B family
XC_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XC_RS00110	COG0793	Belongs to the peptidase S41A family
XC_RS00115	COG4942	peptidase
XC_RS00125	COG2234	aminopeptidase activity
XC_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XC_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XC_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XC_RS00150	COG1064	alcohol dehydrogenase
XC_RS00160	COG0493	'glutamate synthase
XC_RS00165	COG0070	glutamate synthase
XC_RS00165	COG0067	glutamate synthase
XC_RS00165	COG0069	glutamate synthase activity
XC_RS00180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XC_RS00190	COG1741	Belongs to the pirin family
XC_RS00195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XC_RS00215	COG0583	DNA-binding transcription factor activity
XC_RS00270	COG1205	dead DEAH box helicase
XC_RS00270	COG1111	helicase
XC_RS00275	COG3177	Filamentation induced by cAMP protein fic
XC_RS00280	COG1272	protein, Hemolysin III
XC_RS00300	COG2249	NAD(P)H dehydrogenase (quinone) activity
XC_RS00310	COG1733	regulation of RNA biosynthetic process
XC_RS00355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XC_RS00360	COG3237	CsbD-like
XC_RS00410	COG0628	permease
XC_RS00415	COG0657	acetylesterase activity
XC_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XC_RS00430	COG0477	Major facilitator Superfamily
XC_RS00470	COG0714	Associated with various cellular activities
XC_RS00510	COG4772	TonB-dependent receptor
XC_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
XC_RS00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
XC_RS00560	COG4585	Histidine kinase
XC_RS00565	COG2197	response regulator
XC_RS00590	COG3710	Transcriptional regulator
XC_RS00610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XC_RS00660	COG3039	Transposase
XC_RS00700	COG0366	Alpha amylase catalytic
XC_RS00705	COG0366	Alpha amylase catalytic
XC_RS00750	COG2755	lipolytic protein G-D-S-L family
XC_RS00760	COG0657	acetylesterase activity
XC_RS00760	COG2755	lipolytic protein G-D-S-L family
XC_RS00770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XC_RS00785	COG3507	Belongs to the glycosyl hydrolase 43 family
XC_RS00790	COG1609	Transcriptional regulator
XC_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS00810	COG2755	lipolytic protein G-D-S-L family
XC_RS00820	COG3186	Phenylalanine-4-hydroxylase
XC_RS00825	COG1522	sequence-specific DNA binding
XC_RS00835	COG1752	Esterase of the alpha-beta hydrolase superfamily
XC_RS00845	COG1119	ATPase activity
XC_RS00860	COG1125	glycine betaine transport
XC_RS00860	COG0517	IMP dehydrogenase activity
XC_RS00875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XC_RS00880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XC_RS00910	COG0489	protein tyrosine kinase activity
XC_RS00915	COG0588	phosphoglycerate mutase activity
XC_RS00925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS00950	COG1881	PFAM PEBP family protein
XC_RS00965	COG0174	glutamine synthetase
XC_RS00970	COG0347	Belongs to the P(II) protein family
XC_RS00975	COG0004	ammonium transporteR
XC_RS00980	COG3852	Histidine kinase
XC_RS00985	COG2204	response regulator
XC_RS00995	COG2032	superoxide dismutase activity
XC_RS01000	COG2032	superoxide dismutase activity
XC_RS01005	COG0346	lactoylglutathione lyase activity
XC_RS01015	COG0183	Belongs to the thiolase family
XC_RS01055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XC_RS01075	COG0028	Belongs to the TPP enzyme family
XC_RS01090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XC_RS01105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XC_RS01110	COG3177	Filamentation induced by cAMP protein fic
XC_RS01125	COG0596	Alpha beta hydrolase
XC_RS01130	COG0727	PFAM Uncharacterised protein family (UPF0153)
XC_RS01140	COG0318	PFAM AMP-dependent synthetase and ligase
XC_RS01145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XC_RS01160	COG1181	Belongs to the D-alanine--D-alanine ligase family
XC_RS01175	COG0564	pseudouridine synthase activity
XC_RS01195	COG1446	asparaginase
XC_RS01200	COG0339	signal peptide processing
XC_RS01235	COG0583	DNA-binding transcription factor activity
XC_RS01240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XC_RS01245	COG2224	Isocitrate lyase
XC_RS01275	COG4770	biotin carboxylase activity
XC_RS01285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XC_RS01290	COG1960	acyl-CoA dehydrogenase activity
XC_RS01355	COG0697	spore germination
XC_RS01365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XC_RS01375	COG1846	Transcriptional regulator
XC_RS01380	COG1764	response to oxidative stress
XC_RS01405	COG0656	L-ascorbic acid biosynthetic process
XC_RS01410	COG2130	NADP-dependent
XC_RS01425	COG1187	pseudouridine synthase activity
XC_RS01435	COG1643	Atp-dependent helicase
XC_RS01440	COG0840	transmembrane signaling receptor activity
XC_RS01445	COG4807	Protein conserved in bacteria
XC_RS01450	COG2351	hydroxyisourate hydrolase activity
XC_RS01455	COG2072	flavoprotein involved in K transport
XC_RS01475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XC_RS01505	COG3568	Endonuclease Exonuclease Phosphatase
XC_RS01510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS01525	COG1957	nucleoside hydrolase
XC_RS01535	COG2252	PERMEase
XC_RS01555	COG0084	hydrolase, TatD family'
XC_RS01565	COG0583	DNA-binding transcription factor activity
XC_RS01570	COG2814	Major facilitator Superfamily
XC_RS01595	COG1902	pentaerythritol trinitrate reductase activity
XC_RS01620	COG0300	oxidoreductase activity
XC_RS01630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XC_RS01635	COG0583	DNA-binding transcription factor activity
XC_RS01665	COG0702	epimerase
XC_RS01670	COG1733	regulation of RNA biosynthetic process
XC_RS01680	COG0840	transmembrane signaling receptor activity
XC_RS01820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XC_RS01875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XC_RS01900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XC_RS01905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XC_RS01915	COG3485	protocatechuate 3,4-dioxygenase
XC_RS01920	COG3485	protocatechuate 3,4-dioxygenase
XC_RS01930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XC_RS01935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XC_RS01945	COG1414	Transcriptional regulator
XC_RS01955	COG0657	acetylesterase activity
XC_RS01975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XC_RS02025	COG1040	competence protein
XC_RS02040	COG0582	viral genome integration into host DNA
XC_RS02050	COG4774	siderophore transport
XC_RS02060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XC_RS02075	COG4206	TonB-dependent receptor
XC_RS02090	COG2963	transposase activity
XC_RS02095	COG2801	Transposase and inactivated derivatives
XC_RS02105	COG1511	domain protein
XC_RS02105	COG3264	Mechanosensitive ion channel
XC_RS02110	COG1368	sulfuric ester hydrolase activity
XC_RS02115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XC_RS02120	COG2354	Protein conserved in bacteria
XC_RS02125	COG1649	PFAM Uncharacterised BCR, COG1649
XC_RS02135	COG0297	glycogen (starch) synthase activity
XC_RS02145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XC_RS02170	COG0702	epimerase
XC_RS02210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XC_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS02225	COG0513	Belongs to the DEAD box helicase family
XC_RS02235	COG0508	dehydrogenase complex catalyzes the overall conversion of
XC_RS02250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XC_RS02265	COG3104	oligopeptide transport
XC_RS02285	COG2852	Protein conserved in bacteria
XC_RS02310	COG1320	monovalent cation:proton antiporter activity
XC_RS02315	COG2212	antiporter activity
XC_RS02325	COG0651	ATP synthesis coupled electron transport
XC_RS02330	COG1006	Multisubunit Na H antiporter MnhC subunit
XC_RS02335	COG2111	Na H antiporter
XC_RS02335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XC_RS02405	COG0436	Aminotransferase
XC_RS02415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XC_RS02445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XC_RS02550	COG2816	NAD+ diphosphatase activity
XC_RS02555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XC_RS02580	COG2814	Major facilitator Superfamily
XC_RS02585	COG1289	transmembrane transporter activity
XC_RS02590	COG0151	Belongs to the GarS family
XC_RS02600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XC_RS02605	COG2267	carboxylic ester hydrolase activity
XC_RS02610	COG0671	phosphoesterase, PA-phosphatase related
XC_RS02610	COG2453	phosphatase
XC_RS02635	COG4589	Belongs to the CDS family
XC_RS02645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XC_RS02680	COG0439	Biotin carboxylase
XC_RS02690	COG0511	ligase activity, forming carbon-carbon bonds
XC_RS02705	COG1324	tolerance protein
XC_RS02710	COG2356	endonuclease I
XC_RS02725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XC_RS02735	COG1196	nuclear chromosome segregation
XC_RS02770	COG2963	transposase activity
XC_RS02780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XC_RS02805	COG3386	PFAM SMP-30 Gluconolaconase
XC_RS02820	COG3712	iron ion homeostasis
XC_RS02855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XC_RS02880	COG2353	YceI-like domain
XC_RS02935	COG1802	Transcriptional regulator
XC_RS03020	COG0435	Glutathione S-transferase
XC_RS03080	COG2409	Drug exporters of the RND superfamily
XC_RS03090	COG0823	Involved in the tonB-independent uptake of proteins
XC_RS03090	COG1506	peptidase
XC_RS03105	COG1959	2 iron, 2 sulfur cluster binding
XC_RS03145	COG0697	spore germination
XC_RS03160	COG4305	rare lipoprotein A
XC_RS03165	COG5297	Belongs to the glycosyl hydrolase family 6
XC_RS03170	COG1113	amino acid transport
XC_RS03220	COG3447	MASE1 domain protein
XC_RS03220	COG5001	Diguanylate cyclase
XC_RS03220	COG5002	protein histidine kinase activity
XC_RS03225	COG0840	transmembrane signaling receptor activity
XC_RS03230	COG5297	Belongs to the glycosyl hydrolase family 6
XC_RS03230	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XC_RS03235	COG0659	secondary active sulfate transmembrane transporter activity
XC_RS03240	COG3706	GGDEF domain
XC_RS03255	COG0471	metal ion transport
XC_RS03255	COG3273	potassium ion transport
XC_RS03270	COG3275	phosphorelay sensor kinase activity
XC_RS03305	COG1505	serine-type exopeptidase activity
XC_RS03320	COG0436	Aminotransferase
XC_RS03330	COG2832	Protein of unknown function (DUF454)
XC_RS03360	COG2963	transposase activity
XC_RS03400	COG2226	methyltransferase
XC_RS03405	COG3300	MHYT domain
XC_RS03405	COG5001	Diguanylate cyclase
XC_RS03410	COG0308	aminopeptidase N
XC_RS03430	COG2963	transposase activity
XC_RS03460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XC_RS03475	COG3284	Transcriptional regulator
XC_RS03480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XC_RS03485	COG1077	Cell shape determining protein MreB Mrl
XC_RS03490	COG1792	Involved in formation and maintenance of cell shape
XC_RS03505	COG0772	Belongs to the SEDS family
XC_RS03515	COG2963	transposase activity
XC_RS03520	COG2801	Transposase and inactivated derivatives
XC_RS03560	COG2951	lytic endotransglycosylase activity
XC_RS03565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XC_RS03570	COG1686	Belongs to the peptidase S11 family
XC_RS03620	COG1051	belongs to the nudix hydrolase family
XC_RS03620	COG1056	cytidyltransferase-related domain
XC_RS03655	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XC_RS03660	COG0673	inositol 2-dehydrogenase activity
XC_RS03665	COG2823	Periplasmic or secreted lipoprotein
XC_RS03670	COG4251	negative regulation of phosphorylation
XC_RS03675	COG0784	Response regulator, receiver
XC_RS03680	COG4191	Histidine kinase
XC_RS03685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XC_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS03735	COG1459	type II secretion system
XC_RS03750	COG2165	general secretion pathway protein
XC_RS03755	COG4795	General secretion pathway protein
XC_RS03780	COG2188	Transcriptional regulator
XC_RS03790	COG1609	Transcriptional regulator
XC_RS03795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XC_RS03800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XC_RS03840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XC_RS03850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XC_RS03875	COG2205	protein histidine kinase activity
XC_RS03900	COG0583	DNA-binding transcription factor activity
XC_RS03920	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XC_RS03925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XC_RS03930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XC_RS03940	COG0697	spore germination
XC_RS03950	COG1307	EDD domain protein, DegV family
XC_RS03990	COG0402	S-adenosylhomocysteine deaminase activity
XC_RS04010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XC_RS04030	COG0436	Aminotransferase
XC_RS04065	COG2211	Major facilitator Superfamily
XC_RS04070	COG1609	Transcriptional regulator
XC_RS04075	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS04080	COG2851	Citrate transporter
XC_RS04095	COG0642	Histidine kinase
XC_RS04110	COG2197	response regulator
XC_RS04120	COG4191	Histidine kinase
XC_RS04160	COG1560	Kdo2-lipid A biosynthetic process
XC_RS04165	COG1519	Transferase
XC_RS04170	COG1538	Outer membrane efflux protein
XC_RS04175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XC_RS04185	COG3300	MHYT domain
XC_RS04185	COG5001	Diguanylate cyclase
XC_RS04195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XC_RS04205	COG2226	methyltransferase
XC_RS04240	COG0405	Gamma-glutamyltransferase
XC_RS04245	COG0840	transmembrane signaling receptor activity
XC_RS04250	COG1506	peptidase
XC_RS04250	COG4946	Tricorn protease homolog
XC_RS04250	COG0823	Involved in the tonB-independent uptake of proteins
XC_RS04265	COG3710	Transcriptional regulator
XC_RS04285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XC_RS04295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XC_RS04330	COG2963	transposase activity
XC_RS04400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XC_RS04410	COG3781	membrane
XC_RS04415	COG0671	phosphoesterase, PA-phosphatase related
XC_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS04435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XC_RS04440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XC_RS04470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XC_RS04500	COG1773	rubredoxin
XC_RS04505	COG2912	Transglutaminase-like superfamily
XC_RS04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XC_RS04545	COG0006	proline dipeptidase activity
XC_RS04555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XC_RS04555	COG3453	Protein conserved in bacteria
XC_RS04570	COG0725	ABC transporter, periplasmic molybdate-binding protein
XC_RS04575	COG4149	molybdate abc transporter
XC_RS04620	COG1376	ErfK ybiS ycfS ynhG family protein
XC_RS04625	COG0739	heme binding
XC_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS04635	COG0583	DNA-binding transcription factor activity
XC_RS04645	COG2963	transposase activity
XC_RS04650	COG2801	Transposase and inactivated derivatives
XC_RS04655	COG0596	Alpha beta hydrolase
XC_RS04660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XC_RS04665	COG1301	dicarboxylic acid transport
XC_RS04675	COG2304	oxidoreductase activity
XC_RS04695	COG0714	Associated with various cellular activities
XC_RS04725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XC_RS04750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XC_RS04760	COG2721	sulfolactate sulfo-lyase activity
XC_RS04775	COG2271	Major facilitator Superfamily
XC_RS04790	COG0583	DNA-binding transcription factor activity
XC_RS04795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XC_RS04810	COG1561	YicC-like family, N-terminal region
XC_RS04820	COG0346	lactoylglutathione lyase activity
XC_RS04830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XC_RS04855	COG3047	cAMP biosynthetic process
XC_RS04870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XC_RS04900	COG0469	pyruvate kinase activity
XC_RS04905	COG3588	fructose-bisphosphate aldolase
XC_RS04910	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XC_RS04940	COG2198	Histidine kinase
XC_RS04940	COG0784	Response regulator, receiver
XC_RS04940	COG2205	protein histidine kinase activity
XC_RS04970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XC_RS04980	COG0529	Catalyzes the synthesis of activated sulfate
XC_RS04980	COG2895	sulfate adenylyltransferase (ATP) activity
XC_RS04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XC_RS04990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XC_RS04995	COG0308	aminopeptidase N
XC_RS05005	COG1115	amino acid carrier protein
XC_RS05010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XC_RS05015	COG2272	Belongs to the type-B carboxylesterase lipase family
XC_RS05020	COG4948	Mandelate Racemase Muconate Lactonizing
XC_RS05025	COG3250	beta-galactosidase activity
XC_RS05035	COG5297	Belongs to the glycosyl hydrolase family 6
XC_RS05040	COG1609	Transcriptional regulator
XC_RS05075	COG0471	metal ion transport
XC_RS05075	COG3273	potassium ion transport
XC_RS05105	COG0582	viral genome integration into host DNA
XC_RS05125	COG1396	sequence-specific DNA binding
XC_RS05130	COG0583	DNA-binding transcription factor activity
XC_RS05145	COG2801	Transposase and inactivated derivatives
XC_RS05150	COG2963	transposase activity
XC_RS05175	COG2963	transposase activity
XC_RS05185	COG2801	Transposase and inactivated derivatives
XC_RS05190	COG2963	transposase activity
XC_RS05205	COG5001	Diguanylate cyclase
XC_RS05280	COG0745	RESPONSE REGULATOR receiver
XC_RS05315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XC_RS05320	COG1459	type II secretion system
XC_RS05370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XC_RS05370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XC_RS05380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_RS05385	COG0564	pseudouridine synthase activity
XC_RS05390	COG1496	oxidoreductase activity
XC_RS05405	COG0840	transmembrane signaling receptor activity
XC_RS05420	COG3387	PFAM Glycoside hydrolase 15-related
XC_RS05425	COG1877	trehalose-phosphatase activity
XC_RS05470	COG1116	anion transmembrane transporter activity
XC_RS05475	COG0542	response to heat
XC_RS05490	COG4206	TonB-dependent receptor
XC_RS05510	COG1797	cobyrinic acid a,c-diamide synthase activity
XC_RS05515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XC_RS05540	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XC_RS05550	COG0019	diaminopimelate decarboxylase activity
XC_RS05555	COG4264	IucA IucC family
XC_RS05560	COG2814	Major facilitator Superfamily
XC_RS05565	COG4264	IucA IucC family
XC_RS05575	COG4772	TonB-dependent receptor
XC_RS05585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XC_RS05585	COG4651	solute:proton antiporter activity
XC_RS05615	COG0488	(ABC) transporter
XC_RS05635	COG0657	acetylesterase activity
XC_RS05635	COG2755	lipolytic protein G-D-S-L family
XC_RS05655	COG0477	Major facilitator Superfamily
XC_RS05720	COG0824	Thioesterase
XC_RS05730	COG0848	biopolymer transport protein
XC_RS05745	COG2885	chlorophyll binding
XC_RS05755	COG0602	queuosine metabolic process
XC_RS05800	COG0583	DNA-binding transcription factor activity
XC_RS05825	COG1187	pseudouridine synthase activity
XC_RS05845	COG0514	ATP-dependent DNA helicase (RecQ)
XC_RS05850	COG0783	Belongs to the Dps family
XC_RS05855	COG1643	Atp-dependent helicase
XC_RS05900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XC_RS05910	COG1215	transferase activity, transferring glycosyl groups
XC_RS05915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XC_RS05925	COG1199	ATP-dependent helicase activity
XC_RS05935	COG1397	ADP-ribosylglycohydrolase
XC_RS05945	COG0189	ligase activity
XC_RS05960	COG0835	chemotaxis
XC_RS05965	COG0840	transmembrane signaling receptor activity
XC_RS05970	COG2198	Histidine kinase
XC_RS05970	COG0784	Response regulator, receiver
XC_RS05970	COG0643	Histidine kinase
XC_RS05995	COG1595	DNA-templated transcription, initiation
XC_RS06000	COG2304	oxidoreductase activity
XC_RS06005	COG1446	asparaginase
XC_RS06050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XC_RS06060	COG3645	SOS response
XC_RS06085	COG2963	transposase activity
XC_RS06105	COG3537	Alpha-1,2-mannosidase
XC_RS06115	COG1472	Belongs to the glycosyl hydrolase 3 family
XC_RS06125	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XC_RS06130	COG1388	LysM domain
XC_RS06130	COG3858	chitin binding
XC_RS06145	COG0837	glucose binding
XC_RS06150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XC_RS06160	COG0494	nUDIX hydrolase
XC_RS06165	COG1218	3'(2'),5'-bisphosphate nucleotidase
XC_RS06170	COG3956	TIGRFAM MazG family protein
XC_RS06180	COG0330	HflC and HflK could
XC_RS06220	COG1960	acyl-CoA dehydrogenase activity
XC_RS06230	COG1309	transcriptional regulator
XC_RS06245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XC_RS06255	COG0463	Glycosyl transferase, family 2
XC_RS06260	COG0517	IMP dehydrogenase activity
XC_RS06260	COG0516	GMP reductase activity
XC_RS06265	COG2982	Protein involved in outer membrane biogenesis
XC_RS06270	COG1272	protein, Hemolysin III
XC_RS06285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XC_RS06290	COG0626	cystathionine gamma-synthase activity
XC_RS06295	COG0527	aspartate kinase activity
XC_RS06295	COG0460	homoserine dehydrogenase
XC_RS06305	COG1760	l-serine dehydratase
XC_RS06325	COG2353	YceI-like domain
XC_RS06345	COG0477	Major facilitator Superfamily
XC_RS06385	COG1842	Phage shock protein A
XC_RS06410	COG0754	glutathionylspermidine amidase activity
XC_RS06415	COG2814	Major facilitator Superfamily
XC_RS06490	COG0531	amino acid
XC_RS06495	COG2197	response regulator
XC_RS06510	COG1113	amino acid transport
XC_RS06515	COG1271	oxidase subunit
XC_RS06520	COG1294	oxidase, subunit
XC_RS06530	COG2239	Acts as a magnesium transporter
XC_RS06535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XC_RS06540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XC_RS06560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XC_RS06575	COG1137	ATPase activity
XC_RS06590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XC_RS06600	COG0271	Belongs to the BolA IbaG family
XC_RS06625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XC_RS06645	COG0628	permease
XC_RS06655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XC_RS06670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XC_RS06675	COG1555	photosystem II stabilization
XC_RS06720	COG4774	siderophore transport
XC_RS06725	COG2146	nitrite reductase [NAD(P)H] activity
XC_RS06735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XC_RS06740	COG0719	Fe-S assembly protein
XC_RS06745	COG0396	ATPase activity
XC_RS06750	COG0719	Fe-S assembly protein
XC_RS06765	COG0693	protein deglycase activity
XC_RS06800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XC_RS06830	COG0519	Catalyzes the synthesis of GMP from XMP
XC_RS06835	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XC_RS06855	COG1764	response to oxidative stress
XC_RS06865	COG0384	phenazine biosynthesis protein PhzF
XC_RS06870	COG0384	phenazine biosynthesis protein PhzF
XC_RS06875	COG0527	aspartate kinase activity
XC_RS06900	COG0142	geranyltranstransferase activity
XC_RS06905	COG0629	single-stranded DNA binding
XC_RS06915	COG1401	restriction endodeoxyribonuclease activity
XC_RS06925	COG4251	negative regulation of phosphorylation
XC_RS06925	COG3706	GGDEF domain
XC_RS06925	COG2203	Gaf domain
XC_RS06925	COG5001	Diguanylate cyclase
XC_RS06930	COG0604	alcohol dehydrogenase
XC_RS06935	COG2080	2 iron, 2 sulfur cluster binding
XC_RS06940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XC_RS06945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XC_RS06950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XC_RS06955	COG0746	molybdenum cofactor guanylyltransferase activity
XC_RS06985	COG2879	small protein
XC_RS06990	COG1966	Carbon starvation protein
XC_RS06995	COG1741	Belongs to the pirin family
XC_RS07010	COG1741	Belongs to the pirin family
XC_RS07030	COG3590	peptidase
XC_RS07035	COG3039	Transposase
XC_RS07040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS07050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XC_RS07055	COG2200	EAL domain
XC_RS07055	COG2199	diguanylate cyclase activity
XC_RS07055	COG2202	Pas domain
XC_RS07060	COG0835	chemotaxis
XC_RS07065	COG0840	transmembrane signaling receptor activity
XC_RS07070	COG2198	Histidine kinase
XC_RS07070	COG0643	Histidine kinase
XC_RS07080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XC_RS07090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XC_RS07095	COG0745	RESPONSE REGULATOR receiver
XC_RS07105	COG2205	protein histidine kinase activity
XC_RS07115	COG4452	Inner membrane protein CreD
XC_RS07150	COG0735	belongs to the Fur family
XC_RS07165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XC_RS07175	COG1309	transcriptional regulator
XC_RS07180	COG0667	Aldo Keto reductase
XC_RS07195	COG2207	Transcriptional regulator
XC_RS07215	COG0583	DNA-binding transcription factor activity
XC_RS07220	COG2814	Major facilitator Superfamily
XC_RS07250	COG3383	formate dehydrogenase (NAD+) activity
XC_RS07260	COG1271	oxidase subunit
XC_RS07265	COG1294	oxidase, subunit
XC_RS07370	COG5002	protein histidine kinase activity
XC_RS07370	COG5001	Diguanylate cyclase
XC_RS07375	COG1187	pseudouridine synthase activity
XC_RS07410	COG0475	glutathione-regulated potassium exporter activity
XC_RS07415	COG1132	(ABC) transporter
XC_RS07460	COG2155	Conserved Protein
XC_RS07470	COG3118	belongs to the thioredoxin family
XC_RS07495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XC_RS07520	COG2968	Membrane
XC_RS07535	COG3164	Protein of unknown function
XC_RS07545	COG0312	modulator of DNA gyrase
XC_RS07555	COG0312	modulator of DNA gyrase
XC_RS07570	COG0142	geranyltranstransferase activity
XC_RS07585	COG1785	Belongs to the alkaline phosphatase family
XC_RS07590	COG1301	dicarboxylic acid transport
XC_RS07595	COG4106	trans-aconitate 2-methyltransferase activity
XC_RS07620	COG4191	Histidine kinase
XC_RS07625	COG3284	Transcriptional regulator
XC_RS07660	COG0791	NLP P60 protein
XC_RS07665	COG0791	NLP P60 protein
XC_RS07670	COG1047	Peptidyl-prolyl cis-trans
XC_RS07675	COG2311	Membrane
XC_RS07680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XC_RS07685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XC_RS07705	COG3590	peptidase
XC_RS07710	COG3590	peptidase
XC_RS07725	COG0489	protein tyrosine kinase activity
XC_RS07750	COG0412	Dienelactone hydrolase
XC_RS07765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XC_RS07780	COG0494	nUDIX hydrolase
XC_RS07790	COG0433	COG0433 Predicted ATPase
XC_RS07815	COG2890	protein-(glutamine-N5) methyltransferase activity
XC_RS07830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XC_RS07835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XC_RS07920	COG4221	oxidoreductase activity
XC_RS07940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XC_RS07960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XC_RS07965	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XC_RS07985	COG0839	Belongs to the complex I subunit 6 family
XC_RS08005	COG1007	ATP synthesis coupled electron transport
XC_RS08020	COG0195	Participates in both transcription termination and antitermination
XC_RS08080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XC_RS08090	COG2095	MarC family integral membrane protein
XC_RS08100	COG1611	Belongs to the LOG family
XC_RS08105	COG4969	Belongs to the N-Me-Phe pilin family
XC_RS08135	COG4969	Belongs to the N-Me-Phe pilin family
XC_RS08155	COG3505	Type IV secretory pathway VirD4
XC_RS08175	COG2948	multi-organism process
XC_RS08195	COG3702	type iv secretory pathway
XC_RS08215	COG0366	Alpha amylase catalytic
XC_RS08220	COG3039	Transposase
XC_RS08235	COG1082	Xylose isomerase domain protein TIM barrel
XC_RS08265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XC_RS08335	COG0438	transferase activity, transferring glycosyl groups
XC_RS08340	COG0438	transferase activity, transferring glycosyl groups
XC_RS08345	COG2244	polysaccharide biosynthetic process
XC_RS08350	COG0438	transferase activity, transferring glycosyl groups
XC_RS08375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XC_RS08385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XC_RS08415	COG1960	acyl-CoA dehydrogenase activity
XC_RS08440	COG0322	excinuclease ABC activity
XC_RS08465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XC_RS08475	COG0784	Response regulator, receiver
XC_RS08475	COG4191	Histidine kinase
XC_RS08495	COG0552	protein localization to endoplasmic reticulum
XC_RS08505	COG3938	Belongs to the proline racemase family
XC_RS08525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XC_RS08535	COG0006	proline dipeptidase activity
XC_RS08550	COG0531	amino acid
XC_RS08580	COG4206	TonB-dependent receptor
XC_RS08590	COG3507	Belongs to the glycosyl hydrolase 43 family
XC_RS08595	COG1506	peptidase
XC_RS08595	COG0823	Involved in the tonB-independent uptake of proteins
XC_RS08605	COG4206	TonB-dependent receptor
XC_RS08625	COG0742	ribosomal rna small subunit methyltransferase
XC_RS08645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XC_RS08650	COG0405	Gamma-glutamyltransferase
XC_RS08655	COG3291	Pkd domain containing protein
XC_RS08685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XC_RS08705	COG1862	Preprotein translocase
XC_RS08715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XC_RS08735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XC_RS08735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XC_RS08740	COG1105	Belongs to the carbohydrate kinase PfkB family
XC_RS08745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XC_RS08745	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XC_RS08750	COG1609	Transcriptional regulator
XC_RS08755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XC_RS08760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XC_RS08770	COG2902	Dehydrogenase
XC_RS08775	COG2207	Transcriptional regulator
XC_RS08775	COG1609	Transcriptional regulator
XC_RS08780	COG1335	isochorismatase
XC_RS08785	COG0477	Major facilitator Superfamily
XC_RS08795	COG2205	protein histidine kinase activity
XC_RS08795	COG5002	protein histidine kinase activity
XC_RS08795	COG0784	Response regulator, receiver
XC_RS08800	COG2733	membrane
XC_RS08810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XC_RS08815	COG2223	nitrite transmembrane transporter activity
XC_RS08825	COG0243	molybdopterin cofactor binding
XC_RS08835	COG0477	Major facilitator Superfamily
XC_RS08840	COG2703	oxygen carrier activity
XC_RS08850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XC_RS08855	COG0174	glutamine synthetase
XC_RS08860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XC_RS08895	COG3842	ATPase activity
XC_RS08900	COG1176	ABC-type spermidine putrescine transport system, permease component I
XC_RS08905	COG1177	transmembrane transport
XC_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
XC_RS08930	COG4535	Mg2 and Co2 transporter CorC
XC_RS08950	COG1702	phosphate starvation-inducible protein PhoH
XC_RS08970	COG0741	lytic transglycosylase activity
XC_RS08975	COG0723	plastoquinol--plastocyanin reductase activity
XC_RS08980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XC_RS08985	COG2857	Cytochrome c1
XC_RS08990	COG0625	glutathione transferase activity
XC_RS08995	COG2969	positive regulation of protein catabolic process
XC_RS09010	COG1201	RNA secondary structure unwinding
XC_RS09020	COG0840	transmembrane signaling receptor activity
XC_RS09025	COG0835	chemotaxis
XC_RS09075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XC_RS09090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XC_RS09095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XC_RS09095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XC_RS09105	COG0860	N-Acetylmuramoyl-L-alanine amidase
XC_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS09145	COG5001	Diguanylate cyclase
XC_RS09145	COG3300	MHYT domain
XC_RS09150	COG2081	HI0933 family
XC_RS09155	COG4681	YaeQ
XC_RS09190	COG0513	Belongs to the DEAD box helicase family
XC_RS09195	COG0488	(ABC) transporter
XC_RS09210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XC_RS09215	COG0483	inositol monophosphate 1-phosphatase activity
XC_RS09230	COG3300	MHYT domain
XC_RS09230	COG5001	Diguanylate cyclase
XC_RS09235	COG1509	lysine 2,3-aminomutase activity
XC_RS09250	COG0402	S-adenosylhomocysteine deaminase activity
XC_RS09275	COG4677	pectinesterase activity
XC_RS09315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XC_RS09350	COG2166	iron-sulfur cluster assembly
XC_RS09365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XC_RS09375	COG0137	argininosuccinate synthase activity
XC_RS09380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XC_RS09385	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XC_RS09445	COG1294	oxidase, subunit
XC_RS09455	COG4988	ABC transporter
XC_RS09460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XC_RS09520	COG0436	Aminotransferase
XC_RS09540	COG1187	pseudouridine synthase activity
XC_RS09545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XC_RS09550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XC_RS09555	COG2350	Protein conserved in bacteria
XC_RS09580	COG2182	Extracellular solute-binding protein
XC_RS09590	COG0395	ABC-type sugar transport system, permease component
XC_RS09615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XC_RS09620	COG2957	Belongs to the agmatine deiminase family
XC_RS09640	COG0539	negative regulation of cytoplasmic translation
XC_RS09655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XC_RS09670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XC_RS09675	COG0475	glutathione-regulated potassium exporter activity
XC_RS09675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XC_RS09715	COG2197	response regulator
XC_RS09730	COG1335	isochorismatase
XC_RS09745	COG2814	Major facilitator Superfamily
XC_RS09760	COG1914	H( )-stimulated, divalent metal cation uptake system
XC_RS09780	COG0668	transmembrane transport
XC_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS09810	COG1183	phosphatidylcholine synthase activity
XC_RS09820	COG3243	poly(R)-hydroxyalkanoic acid synthase
XC_RS09835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XC_RS09835	COG0723	plastoquinol--plastocyanin reductase activity
XC_RS09845	COG2183	response to ionizing radiation
XC_RS09850	COG5001	Diguanylate cyclase
XC_RS09915	COG0800	Aldolase
XC_RS09920	COG0129	dihydroxy-acid dehydratase activity
XC_RS09925	COG0363	glucosamine-6-phosphate deaminase activity
XC_RS09935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XC_RS09945	COG0354	folic acid binding
XC_RS09955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XC_RS09960	COG1053	succinate dehydrogenase
XC_RS09970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XC_RS09985	COG4591	ABC-type transport system involved in lipoprotein release permease component
XC_RS10005	COG0811	peptide transport
XC_RS10030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XC_RS10045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XC_RS10065	COG0582	viral genome integration into host DNA
XC_RS10110	COG2963	transposase activity
XC_RS10120	COG3039	Transposase
XC_RS10210	COG2003	Belongs to the UPF0758 family
XC_RS10335	COG2826	transposase and inactivated derivatives, IS30 family
XC_RS10380	COG0270	DNA (cytosine-5-)-methyltransferase activity
XC_RS10385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XC_RS10390	COG0629	single-stranded DNA binding
XC_RS10455	COG1061	Type III restriction enzyme res subunit
XC_RS10460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XC_RS10475	COG4644	lycopene metabolic process
XC_RS10525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XC_RS10560	COG1530	ribonuclease E activity
XC_RS10570	COG0428	transporter
XC_RS10715	COG3459	Glycosyltransferase 36 associated
XC_RS10725	COG0784	Response regulator, receiver
XC_RS10725	COG4191	Histidine kinase
XC_RS10755	COG0840	transmembrane signaling receptor activity
XC_RS10765	COG1238	metal cluster binding
XC_RS10790	COG1733	regulation of RNA biosynthetic process
XC_RS10805	COG1999	signal sequence binding
XC_RS10820	COG3590	peptidase
XC_RS10885	COG5001	Diguanylate cyclase
XC_RS10895	COG2201	protein-glutamate methylesterase activity
XC_RS10900	COG3685	Protein conserved in bacteria
XC_RS10915	COG0579	oxidoreductase
XC_RS10925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XC_RS10935	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XC_RS10955	COG0243	molybdopterin cofactor binding
XC_RS10965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XC_RS10970	COG2223	nitrite transmembrane transporter activity
XC_RS10975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XC_RS10985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XC_RS10985	COG1648	precorrin-2 dehydrogenase activity
XC_RS10995	COG0746	molybdenum cofactor guanylyltransferase activity
XC_RS11000	COG0303	'Molybdopterin
XC_RS11010	COG0708	Exodeoxyribonuclease III
XC_RS11035	COG2124	cytochrome p450
XC_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS11055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XC_RS11070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_RS11105	COG1250	3-hydroxyacyl-CoA dehydrogenase
XC_RS11105	COG1024	Enoyl-CoA hydratase
XC_RS11110	COG0183	Belongs to the thiolase family
XC_RS11115	COG0038	chloride channel
XC_RS11120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XC_RS11140	COG1674	ftsk spoiiie
XC_RS11145	COG0492	ferredoxin-NADP+ reductase activity
XC_RS11165	COG0542	response to heat
XC_RS11185	COG2915	High frequency lysogenization protein hflD homolog
XC_RS11220	COG4191	Histidine kinase
XC_RS11240	COG0784	Response regulator, receiver
XC_RS11240	COG0835	chemotaxis
XC_RS11250	COG1558	bacterial-type flagellum-dependent cell motility
XC_RS11255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XC_RS11265	COG4787	bacterial-type flagellum-dependent cell motility
XC_RS11285	COG3951	Flagellar rod assembly protein muramidase FlgJ
XC_RS11285	COG1705	Flagellar rod assembly protein muramidase FlgJ
XC_RS11295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XC_RS11300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XC_RS11305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XC_RS11335	COG2201	protein-glutamate methylesterase activity
XC_RS11365	COG1216	Glycosyl transferase, family 2
XC_RS11365	COG0438	transferase activity, transferring glycosyl groups
XC_RS11370	COG1677	Flagellar hook-basal body complex protein FliE
XC_RS11435	COG1987	bacterial-type flagellum assembly
XC_RS11440	COG1684	flagellar biosynthetic protein fliR
XC_RS11495	COG0784	Response regulator, receiver
XC_RS11495	COG0643	Histidine kinase
XC_RS11495	COG2198	Histidine kinase
XC_RS11545	COG0672	)-iron permease
XC_RS11560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XC_RS11565	COG1360	Flagellar Motor Protein
XC_RS11570	COG1192	Involved in chromosome partitioning
XC_RS11575	COG0835	chemotaxis
XC_RS11585	COG0745	RESPONSE REGULATOR receiver
XC_RS11595	COG0840	transmembrane signaling receptor activity
XC_RS11610	COG0840	transmembrane signaling receptor activity
XC_RS11615	COG0840	transmembrane signaling receptor activity
XC_RS11620	COG0840	transmembrane signaling receptor activity
XC_RS11630	COG0840	transmembrane signaling receptor activity
XC_RS11645	COG0835	chemotaxis
XC_RS11655	COG0840	transmembrane signaling receptor activity
XC_RS11680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XC_RS11710	COG0318	PFAM AMP-dependent synthetase and ligase
XC_RS11715	COG1024	Enoyl-CoA hydratase
XC_RS11725	COG2205	protein histidine kinase activity
XC_RS11725	COG2198	Histidine kinase
XC_RS11725	COG0784	Response regulator, receiver
XC_RS11740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XC_RS11745	COG3279	Response regulator of the LytR AlgR family
XC_RS11770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XC_RS11780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XC_RS11785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XC_RS11795	COG0505	Belongs to the CarA family
XC_RS11805	COG2258	MOSC domain
XC_RS11810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XC_RS11835	COG1024	Enoyl-CoA hydratase
XC_RS11870	COG0277	FAD linked oxidase domain protein
XC_RS11875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XC_RS11890	COG0531	amino acid
XC_RS11895	COG0531	amino acid
XC_RS11925	COG0140	phosphoribosyl-ATP diphosphatase activity
XC_RS11925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XC_RS11945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XC_RS11945	COG0131	Imidazoleglycerol-phosphate dehydratase
XC_RS11975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XC_RS11985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XC_RS12005	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XC_RS12025	COG2963	transposase activity
XC_RS12050	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XC_RS12050	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XC_RS12075	COG2814	Major facilitator Superfamily
XC_RS12255	COG1012	belongs to the aldehyde dehydrogenase family
XC_RS12280	COG0697	spore germination
XC_RS12285	COG1794	racemase activity, acting on amino acids and derivatives
XC_RS12295	COG0671	phosphoesterase, PA-phosphatase related
XC_RS12310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XC_RS12315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XC_RS12320	COG2203	Gaf domain
XC_RS12320	COG3706	GGDEF domain
XC_RS12320	COG4251	negative regulation of phosphorylation
XC_RS12320	COG5001	Diguanylate cyclase
XC_RS12330	COG1472	Belongs to the glycosyl hydrolase 3 family
XC_RS12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
XC_RS12410	COG0477	Major facilitator Superfamily
XC_RS12420	COG1070	Carbohydrate kinase
XC_RS12430	COG1501	Belongs to the glycosyl hydrolase 31 family
XC_RS12465	COG0800	Aldolase
XC_RS12480	COG3734	2-keto-3-deoxy-galactonokinase
XC_RS12485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XC_RS12495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XC_RS12510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XC_RS12515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XC_RS12525	COG0352	thiamine-phosphate diphosphorylase activity
XC_RS12525	COG0351	phosphomethylpyrimidine kinase
XC_RS12550	COG0583	DNA-binding transcription factor activity
XC_RS12555	COG1741	Belongs to the pirin family
XC_RS12590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XC_RS12605	COG4771	TonB-dependent receptor
XC_RS12610	COG1546	Belongs to the CinA family
XC_RS12615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XC_RS12630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XC_RS12635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XC_RS12645	COG1534	Rna-binding protein
XC_RS12660	COG1238	metal cluster binding
XC_RS12675	COG2840	Smr protein MutS2
XC_RS12730	COG2134	cdp-diacylglycerol pyrophosphatase
XC_RS12755	COG1253	flavin adenine dinucleotide binding
XC_RS12770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XC_RS12775	COG0477	Major facilitator Superfamily
XC_RS12780	COG1132	(ABC) transporter
XC_RS12800	COG0438	transferase activity, transferring glycosyl groups
XC_RS12805	COG0438	transferase activity, transferring glycosyl groups
XC_RS12810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XC_RS12840	COG2244	polysaccharide biosynthetic process
XC_RS12855	COG3038	cytochrome b561
XC_RS12875	COG1595	DNA-templated transcription, initiation
XC_RS12890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XC_RS12910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XC_RS12925	COG4191	Histidine kinase
XC_RS12925	COG0784	Response regulator, receiver
XC_RS12930	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XC_RS12975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XC_RS13020	COG2963	transposase activity
XC_RS13025	COG2801	Transposase and inactivated derivatives
XC_RS13040	COG2963	transposase activity
XC_RS13060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XC_RS13080	COG2963	transposase activity
XC_RS13125	COG2003	Belongs to the UPF0758 family
XC_RS13185	COG3039	Transposase
XC_RS13195	COG2963	transposase activity
XC_RS13200	COG2963	transposase activity
XC_RS13205	COG2801	Transposase and inactivated derivatives
XC_RS13215	COG2801	Transposase and inactivated derivatives
XC_RS13220	COG2963	transposase activity
XC_RS13275	COG0583	DNA-binding transcription factor activity
XC_RS13290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XC_RS13300	COG0077	Prephenate dehydratase
XC_RS13300	COG1605	Chorismate mutase
XC_RS13310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XC_RS13365	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XC_RS13375	COG4993	Dehydrogenase
XC_RS13395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XC_RS13405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XC_RS13440	COG0316	Belongs to the HesB IscA family
XC_RS13470	COG0288	reversible hydration of carbon dioxide
XC_RS13495	COG2925	Exonuclease
XC_RS13510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XC_RS13530	COG0488	(ABC) transporter
XC_RS13535	COG2264	protein methyltransferase activity
XC_RS13570	COG0494	nUDIX hydrolase
XC_RS13580	COG1024	Enoyl-CoA hydratase
XC_RS13590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XC_RS13595	COG0659	secondary active sulfate transmembrane transporter activity
XC_RS13620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XC_RS13625	COG0573	inorganic phosphate transmembrane transporter activity
XC_RS13630	COG0581	inorganic phosphate transmembrane transporter activity
XC_RS13640	COG0704	Plays a role in the regulation of phosphate uptake
XC_RS13660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XC_RS13670	COG0557	exoribonuclease II activity
XC_RS13685	COG1960	acyl-CoA dehydrogenase activity
XC_RS13690	COG1960	acyl-CoA dehydrogenase activity
XC_RS13695	COG1960	acyl-CoA dehydrogenase activity
XC_RS13700	COG1960	acyl-CoA dehydrogenase activity
XC_RS13705	COG2226	methyltransferase
XC_RS13710	COG0646	methionine synthase
XC_RS13710	COG1410	methionine synthase
XC_RS13715	COG0646	methionine synthase
XC_RS13715	COG1410	methionine synthase
XC_RS13725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XC_RS13735	COG1609	Transcriptional regulator
XC_RS13770	COG0386	Belongs to the glutathione peroxidase family
XC_RS13775	COG1725	Transcriptional regulator
XC_RS13780	COG1131	(ABC) transporter
XC_RS13810	COG1253	flavin adenine dinucleotide binding
XC_RS13830	COG2850	peptidyl-arginine hydroxylation
XC_RS13865	COG1132	(ABC) transporter
XC_RS13870	COG0583	DNA-binding transcription factor activity
XC_RS13875	COG2274	protein secretion by the type I secretion system
XC_RS13900	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XC_RS13915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XC_RS13920	COG1420	regulation of RNA biosynthetic process
XC_RS13925	COG0497	DNA recombination
XC_RS13935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_RS13955	COG1404	Belongs to the peptidase S8 family
XC_RS14010	COG2963	transposase activity
XC_RS14025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XC_RS14065	COG3706	GGDEF domain
XC_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS14095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XC_RS14105	COG0583	DNA-binding transcription factor activity
XC_RS14115	COG0415	Belongs to the DNA photolyase family
XC_RS14120	COG0305	Participates in initiation and elongation during chromosome replication
XC_RS14130	COG0367	asparagine synthase
XC_RS14145	COG1960	acyl-CoA dehydrogenase activity
XC_RS14160	COG0084	hydrolase, TatD family'
XC_RS14165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XC_RS14225	COG0386	Belongs to the glutathione peroxidase family
XC_RS14230	COG0339	signal peptide processing
XC_RS14260	COG3104	oligopeptide transport
XC_RS14290	COG2814	Major facilitator Superfamily
XC_RS14295	COG1566	PFAM secretion protein HlyD family protein
XC_RS14335	COG4774	siderophore transport
XC_RS14345	COG0367	asparagine synthase
XC_RS14360	COG1393	Belongs to the ArsC family
XC_RS14430	COG0528	UMP kinase activity
XC_RS14440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XC_RS14445	COG0575	Belongs to the CDS family
XC_RS14455	COG0750	zinc metalloprotease
XC_RS14510	COG1981	membrane
XC_RS14530	COG1695	Transcriptional regulator
XC_RS14560	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XC_RS14570	COG2040	homocysteine
XC_RS14575	COG0833	amino acid
XC_RS14585	COG0346	lactoylglutathione lyase activity
XC_RS14610	COG2878	Part of a membrane complex involved in electron transport
XC_RS14625	COG1595	DNA-templated transcription, initiation
XC_RS14650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XC_RS14665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XC_RS14670	COG0251	oxidation-reduction process
XC_RS14680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XC_RS14680	COG0392	lysyltransferase activity
XC_RS14720	COG2814	Major facilitator Superfamily
XC_RS14725	COG1902	pentaerythritol trinitrate reductase activity
XC_RS14745	COG2824	Alkylphosphonate utilization operon protein PhnA
XC_RS14755	COG1047	Peptidyl-prolyl cis-trans
XC_RS14790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XC_RS14800	COG5487	UPF0391 membrane protein
XC_RS14805	COG1451	nucleotide metabolic process
XC_RS14825	COG0183	Belongs to the thiolase family
XC_RS14855	COG1793	dna ligase
XC_RS14855	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XC_RS14865	COG1793	dna ligase
XC_RS14870	COG1201	RNA secondary structure unwinding
XC_RS14880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XC_RS14885	COG1278	Cold shock
XC_RS14890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XC_RS14895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XC_RS14905	COG3046	protein related to deoxyribodipyrimidine photolyase
XC_RS14910	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XC_RS14910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XC_RS14915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XC_RS14920	COG2954	triphosphatase activity
XC_RS14970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XC_RS15000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XC_RS15005	COG1024	Enoyl-CoA hydratase
XC_RS15010	COG1960	acyl-CoA dehydrogenase activity
XC_RS15020	COG3800	Transcriptional regulator
XC_RS15020	COG1396	sequence-specific DNA binding
XC_RS15030	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XC_RS15035	COG3250	beta-galactosidase activity
XC_RS15075	COG3039	Transposase
XC_RS15165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XC_RS15220	COG5297	Belongs to the glycosyl hydrolase family 6
XC_RS15240	COG1309	transcriptional regulator
XC_RS15245	COG0436	Aminotransferase
XC_RS15250	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS15255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XC_RS15270	COG3483	tryptophan 2,3-dioxygenase activity
XC_RS15285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XC_RS15305	COG0534	Mate efflux family protein
XC_RS15335	COG2070	2-Nitropropane dioxygenase
XC_RS15350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XC_RS15355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XC_RS15365	COG3534	alpha-L-arabinofuranosidase
XC_RS15390	COG0784	Response regulator, receiver
XC_RS15390	COG4191	Histidine kinase
XC_RS15395	COG4999	Histidine kinase
XC_RS15395	COG3437	response regulator, receiver
XC_RS15395	COG2205	protein histidine kinase activity
XC_RS15395	COG3850	Histidine kinase
XC_RS15400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XC_RS15410	COG2205	protein histidine kinase activity
XC_RS15415	COG5507	3-demethylubiquinone-9 3-methyltransferase
XC_RS15425	COG4771	TonB-dependent receptor
XC_RS15460	COG2172	sigma factor antagonist activity
XC_RS15465	COG1366	Belongs to the anti-sigma-factor antagonist family
XC_RS15470	COG1366	Belongs to the anti-sigma-factor antagonist family
XC_RS15475	COG1902	pentaerythritol trinitrate reductase activity
XC_RS15485	COG0326	Molecular chaperone. Has ATPase activity
XC_RS15490	COG2207	Transcriptional regulator
XC_RS15505	COG3152	Membrane
XC_RS15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XC_RS15525	COG1845	cytochrome c oxidase, subunit III
XC_RS15530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XC_RS15560	COG0196	riboflavin kinase activity
XC_RS15590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XC_RS15595	COG0824	Thioesterase
XC_RS15600	COG1024	Enoyl-CoA hydratase
XC_RS15605	COG1946	Acyl-CoA thioesterase
XC_RS15615	COG1595	DNA-templated transcription, initiation
XC_RS15685	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XC_RS15710	COG2197	response regulator
XC_RS15715	COG4585	Histidine kinase
XC_RS15730	COG2894	cell division
XC_RS15745	COG5002	protein histidine kinase activity
XC_RS15750	COG0745	RESPONSE REGULATOR receiver
XC_RS15785	COG2814	Major facilitator Superfamily
XC_RS15810	COG0656	L-ascorbic acid biosynthetic process
XC_RS15815	COG0753	catalase activity
XC_RS15825	COG1917	Cupin 2, conserved barrel domain protein
XC_RS15825	COG2207	Transcriptional regulator
XC_RS15840	COG1506	peptidase
XC_RS15840	COG0823	Involved in the tonB-independent uptake of proteins
XC_RS15850	COG1297	OPT oligopeptide transporter protein
XC_RS15875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XC_RS15900	COG2080	2 iron, 2 sulfur cluster binding
XC_RS15905	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XC_RS15910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XC_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS15960	COG3537	Alpha-1,2-mannosidase
XC_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS15975	COG3387	PFAM Glycoside hydrolase 15-related
XC_RS15990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XC_RS16025	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XC_RS16040	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XC_RS16090	COG0308	aminopeptidase N
XC_RS16105	COG0330	HflC and HflK could
XC_RS16110	COG0330	HflC and HflK could
XC_RS16130	COG0678	peroxiredoxin activity
XC_RS16140	COG4953	penicillin-binding protein 1C
XC_RS16165	COG2373	Large extracellular alpha-helical protein
XC_RS16190	COG3609	addiction module antidote protein, CC2985 family
XC_RS16210	COG3829	transcription factor binding
XC_RS16250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XC_RS16255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XC_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS16275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XC_RS16290	COG1399	metal-binding, possibly nucleic acid-binding protein
XC_RS16325	COG0714	Associated with various cellular activities
XC_RS16345	COG0537	adenosine 5'-monophosphoramidase activity
XC_RS16370	COG0314	molybdopterin synthase activity
XC_RS16375	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XC_RS16395	COG1234	tRNA 3'-trailer cleavage
XC_RS16405	COG0859	PFAM glycosyl transferase family 9
XC_RS16420	COG0631	protein serine/threonine phosphatase activity
XC_RS16425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XC_RS16455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XC_RS16530	COG0473	3-isopropylmalate dehydrogenase activity
XC_RS16545	COG4783	chaperone-mediated protein folding
XC_RS16550	COG0745	RESPONSE REGULATOR receiver
XC_RS16560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XC_RS16570	COG0438	transferase activity, transferring glycosyl groups
XC_RS16575	COG0671	phosphoesterase, PA-phosphatase related
XC_RS16580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XC_RS16590	COG3291	Pkd domain containing protein
XC_RS16595	COG2833	Protein of unknown function (DUF455)
XC_RS16615	COG0285	dihydrofolate synthase activity
XC_RS16630	COG0406	alpha-ribazole phosphatase activity
XC_RS16655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XC_RS16660	COG4208	sulfate ABC transporter
XC_RS16665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XC_RS16670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XC_RS16705	COG1902	pentaerythritol trinitrate reductase activity
XC_RS16705	COG0446	pyridine nucleotide-disulphide oxidoreductase
XC_RS16730	COG0625	glutathione transferase activity
XC_RS16740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XC_RS16745	COG1217	gtp-binding protein TYPA
XC_RS16755	COG0154	amidase activity
XC_RS16765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XC_RS16800	COG0201	protein transport
XC_RS16960	COG0250	Participates in transcription elongation, termination and antitermination
XC_RS16995	COG0012	GTP binding
XC_RS17010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XC_RS17050	COG0521	Mo-molybdopterin cofactor biosynthetic process
XC_RS17070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XC_RS17100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XC_RS17105	COG1404	Belongs to the peptidase S8 family
XC_RS17110	COG1404	Belongs to the peptidase S8 family
XC_RS17115	COG1404	Belongs to the peptidase S8 family
XC_RS17120	COG1404	Belongs to the peptidase S8 family
XC_RS17125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XC_RS17175	COG0778	Nitroreductase
XC_RS17180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XC_RS17180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XC_RS17200	COG2890	protein-(glutamine-N5) methyltransferase activity
XC_RS17210	COG3634	alkyl hydroperoxide reductase activity
XC_RS17215	COG0583	DNA-binding transcription factor activity
XC_RS17220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XC_RS17245	COG2197	response regulator
XC_RS17250	COG5002	protein histidine kinase activity
XC_RS17250	COG0784	Response regulator, receiver
XC_RS17250	COG2205	protein histidine kinase activity
XC_RS17280	COG0697	spore germination
XC_RS17310	COG3386	PFAM SMP-30 Gluconolaconase
XC_RS17330	COG1024	Enoyl-CoA hydratase
XC_RS17340	COG0318	PFAM AMP-dependent synthetase and ligase
XC_RS17345	COG0583	DNA-binding transcription factor activity
XC_RS17350	COG3384	dioxygenase
XC_RS17380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XC_RS17385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XC_RS17395	COG2096	Adenosyltransferase
XC_RS17400	COG0123	including yeast histone deacetylase and acetoin utilization protein
XC_RS17430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XC_RS17465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XC_RS17475	COG0642	Histidine kinase
XC_RS17490	COG4181	ATPase activity
XC_RS17500	COG2175	clavaminate synthase activity
XC_RS17510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XC_RS17535	COG4771	TonB-dependent receptor
XC_RS17545	COG0667	Aldo Keto reductase
XC_RS17550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XC_RS17560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XC_RS17645	COG0366	Alpha amylase catalytic
XC_RS17675	COG0604	alcohol dehydrogenase
XC_RS17675	COG3321	synthase
XC_RS17675	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS17690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XC_RS17705	COG0494	nUDIX hydrolase
XC_RS17720	COG0739	heme binding
XC_RS17745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XC_RS17750	COG1181	Belongs to the D-alanine--D-alanine ligase family
XC_RS17790	COG3116	cell division
XC_RS17835	COG1988	membrane-bound metal-dependent
XC_RS17840	COG0277	FAD linked oxidase domain protein
XC_RS17850	COG0745	RESPONSE REGULATOR receiver
XC_RS17855	COG2205	protein histidine kinase activity
XC_RS17865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XC_RS17870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XC_RS17885	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XC_RS17915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XC_RS17915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XC_RS17940	COG0488	(ABC) transporter
XC_RS17945	COG0242	peptide deformylase activity
XC_RS17950	COG1393	Belongs to the ArsC family
XC_RS17965	COG0457	Tetratricopeptide repeat
XC_RS18015	COG2188	Transcriptional regulator
XC_RS18025	COG1450	Type ii and iii secretion system protein
XC_RS18040	COG3166	PFAM Fimbrial assembly family protein
XC_RS18045	COG3156	type II secretion system protein K
XC_RS18050	COG4795	General secretion pathway protein
XC_RS18055	COG2165	general secretion pathway protein
XC_RS18060	COG4970	Tfp pilus assembly protein FimT
XC_RS18065	COG2165	general secretion pathway protein
XC_RS18075	COG1459	type II secretion system
XC_RS18080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XC_RS18085	COG1404	Belongs to the peptidase S8 family
XC_RS18105	COG0047	phosphoribosylformylglycinamidine synthase activity
XC_RS18105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XC_RS18110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XC_RS18115	COG4974	Belongs to the 'phage' integrase family
XC_RS18130	COG0795	lipopolysaccharide-transporting ATPase activity
XC_RS18185	COG1183	phosphatidylcholine synthase activity
XC_RS18210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XC_RS18215	COG1127	ABC transporter
XC_RS18220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XC_RS18220	COG3218	ABC-type transport auxiliary lipoprotein component
XC_RS18240	COG3754	Rhamnan synthesis protein F
XC_RS18245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XC_RS18250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XC_RS18255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XC_RS18260	COG0662	Cupin 2, conserved barrel domain protein
XC_RS18260	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XC_RS18285	COG2086	electron transfer activity
XC_RS18295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XC_RS18295	COG0662	Cupin 2, conserved barrel domain protein
XC_RS18300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XC_RS18305	COG0463	Glycosyl transferase, family 2
XC_RS18330	COG2963	transposase activity
XC_RS18335	COG2801	Transposase and inactivated derivatives
XC_RS18350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XC_RS18365	COG0438	transferase activity, transferring glycosyl groups
XC_RS18390	COG0626	cystathionine gamma-synthase activity
XC_RS18420	COG0625	glutathione transferase activity
XC_RS18430	COG0513	Belongs to the DEAD box helicase family
XC_RS18435	COG0720	synthase
XC_RS18450	COG1956	GAF domain-containing protein
XC_RS18480	COG0339	signal peptide processing
XC_RS18485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XC_RS18530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XC_RS18540	COG1136	(ABC) transporter
XC_RS18550	COG0577	efflux transmembrane transporter activity
XC_RS18550	COG1136	(ABC) transporter
XC_RS18570	COG2963	transposase activity
XC_RS18575	COG2801	Transposase and inactivated derivatives
XC_RS18635	COG0356	it plays a direct role in the translocation of protons across the membrane
XC_RS18650	COG1228	amidohydrolase
XC_RS18665	COG0508	dehydrogenase complex catalyzes the overall conversion of
XC_RS18710	COG2011	ABC-type metal ion transport system permease component
XC_RS18720	COG0697	spore germination
XC_RS18750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XC_RS18755	COG1187	pseudouridine synthase activity
XC_RS18760	COG2813	Specifically methylates the guanine in position
XC_RS18780	COG5002	protein histidine kinase activity
XC_RS18860	COG0842	Transport permease protein
XC_RS18865	COG1131	(ABC) transporter
XC_RS18870	COG0025	NhaP-type Na H and K H
XC_RS18875	COG3795	YCII-related domain
XC_RS18880	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XC_RS18885	COG1573	uracil-dna glycosylase
XC_RS18895	COG3384	dioxygenase
XC_RS18900	COG0583	DNA-binding transcription factor activity
XC_RS18910	COG0667	Aldo Keto reductase
XC_RS18920	COG3590	peptidase
XC_RS18935	COG0531	amino acid
XC_RS18950	COG2972	Histidine kinase
XC_RS18965	COG1335	isochorismatase
XC_RS18970	COG3685	Protein conserved in bacteria
XC_RS18975	COG3685	Protein conserved in bacteria
XC_RS18980	COG3546	catalase activity
XC_RS19010	COG2204	response regulator
XC_RS19020	COG1271	oxidase subunit
XC_RS19025	COG1294	oxidase, subunit
XC_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS19045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XC_RS19065	COG1132	(ABC) transporter
XC_RS19080	COG1063	alcohol dehydrogenase
XC_RS19105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XC_RS19160	COG0251	oxidation-reduction process
XC_RS19180	COG0667	Aldo Keto reductase
XC_RS19185	COG0583	DNA-binding transcription factor activity
XC_RS19205	COG2203	Gaf domain
XC_RS19205	COG3706	GGDEF domain
XC_RS19205	COG4251	negative regulation of phosphorylation
XC_RS19205	COG5001	Diguanylate cyclase
XC_RS19220	COG2963	transposase activity
XC_RS19240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XC_RS19250	COG1560	Kdo2-lipid A biosynthetic process
XC_RS19260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XC_RS19295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XC_RS19295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XC_RS19305	COG0242	peptide deformylase activity
XC_RS19310	COG1652	LysM domain
XC_RS19315	COG0758	DNA mediated transformation
XC_RS19335	COG1754	DNA topoisomerase type I activity
XC_RS19335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XC_RS19355	COG2203	Gaf domain
XC_RS19355	COG5001	Diguanylate cyclase
XC_RS19355	COG4251	negative regulation of phosphorylation
XC_RS19355	COG3706	GGDEF domain
XC_RS19360	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS19370	COG0616	signal peptide processing
XC_RS19375	COG0534	Mate efflux family protein
XC_RS19390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XC_RS19395	COG0625	glutathione transferase activity
XC_RS19410	COG1252	NADH dehydrogenase
XC_RS19415	COG2860	membrane
XC_RS19420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XC_RS19430	COG2201	protein-glutamate methylesterase activity
XC_RS19435	COG2177	Part of the ABC transporter FtsEX involved in
XC_RS19440	COG2884	Cell division ATP-binding protein ftsE
XC_RS19450	COG3118	belongs to the thioredoxin family
XC_RS19455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XC_RS19500	COG1473	amidohydrolase
XC_RS19505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XC_RS19535	COG4941	Belongs to the sigma-70 factor family
XC_RS19540	COG5383	Protein conserved in bacteria
XC_RS19580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XC_RS19585	COG3501	Rhs element vgr protein
XC_RS19585	COG3409	Peptidoglycan-binding domain 1 protein
XC_RS19600	COG3023	N-Acetylmuramoyl-L-alanine amidase
XC_RS19610	COG4948	Mandelate Racemase Muconate Lactonizing
XC_RS19620	COG0531	amino acid
XC_RS19635	COG4682	membrane
XC_RS19640	COG2133	pyrroloquinoline quinone binding
XC_RS19650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XC_RS19665	COG1610	YqeY-like protein
XC_RS19670	COG1295	ribonuclease BN
XC_RS19675	COG0358	DNA primase activity
XC_RS19725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XC_RS19740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XC_RS19785	COG2801	Transposase and inactivated derivatives
XC_RS19790	COG2963	transposase activity
XC_RS19800	COG2801	Transposase and inactivated derivatives
XC_RS19805	COG2963	transposase activity
XC_RS19815	COG2801	Transposase and inactivated derivatives
XC_RS19820	COG2963	transposase activity
XC_RS19830	COG3039	Transposase
XC_RS19870	COG0739	heme binding
XC_RS19890	COG0708	Exodeoxyribonuclease III
XC_RS19905	COG1192	Involved in chromosome partitioning
XC_RS19910	COG1475	DNA binding
XC_RS19930	COG0463	Glycosyl transferase, family 2
XC_RS19955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XC_RS19980	COG4221	oxidoreductase activity
XC_RS19985	COG2755	lipolytic protein G-D-S-L family
XC_RS19985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XC_RS20000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XC_RS20005	COG1166	arginine decarboxylase activity
XC_RS20030	COG2960	long-chain fatty acid transporting porin activity
XC_RS20035	COG0606	chelatase, subunit chli
XC_RS20050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XC_RS20085	COG1690	Belongs to the RtcB family
XC_RS20125	COG1090	epimerase
XC_RS20130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XC_RS20145	COG0642	Histidine kinase
XC_RS20165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XC_RS20190	COG1011	Hydrolase
XC_RS20195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XC_RS20220	COG2197	response regulator
XC_RS20225	COG4585	Histidine kinase
XC_RS20235	COG1136	(ABC) transporter
XC_RS20260	COG0697	spore germination
XC_RS20290	COG0180	Tryptophanyl-tRNA synthetase
XC_RS20295	COG3237	CsbD-like
XC_RS20370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XC_RS20370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XC_RS20380	COG3228	Belongs to the MtfA family
XC_RS20410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XC_RS20435	COG1199	ATP-dependent helicase activity
XC_RS20495	COG0625	glutathione transferase activity
XC_RS20530	COG4555	ABC transporter
XC_RS20540	COG1476	TRANSCRIPTIONal
XC_RS20555	COG1230	cation diffusion facilitator family transporter
XC_RS20565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XC_RS20570	COG1131	(ABC) transporter
XC_RS20575	COG0842	Transport permease protein
XC_RS20585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XC_RS20595	COG1607	acyl-coa hydrolase
XC_RS20610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XC_RS20615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XC_RS20625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XC_RS20625	COG1042	CoA-binding domain protein
XC_RS20625	COG0045	succinate-CoA ligase (ADP-forming) activity
XC_RS20630	COG2239	Acts as a magnesium transporter
XC_RS20645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XC_RS20650	COG3387	PFAM Glycoside hydrolase 15-related
XC_RS20670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XC_RS20680	COG0463	Glycosyl transferase, family 2
XC_RS20695	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS20725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XC_RS20740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XC_RS20815	COG0210	DNA helicase
XC_RS20825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS20830	COG0583	DNA-binding transcription factor activity
XC_RS20835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XC_RS20845	COG2159	amidohydrolase
XC_RS20905	COG2091	lysine biosynthetic process via aminoadipic acid
XC_RS20965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XC_RS20975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XC_RS20980	COG3162	membrane
XC_RS21015	COG3507	Belongs to the glycosyl hydrolase 43 family
XC_RS21030	COG1028	Short-chain dehydrogenase reductase Sdr
XC_RS21035	COG0179	Fumarylacetoacetate (FAA) hydrolase
XC_RS21040	COG4948	Mandelate Racemase Muconate Lactonizing
XC_RS21045	COG3254	rhamnose metabolic process
XC_RS21050	COG0738	Major facilitator superfamily
XC_RS21055	COG1414	Transcriptional regulator
XC_RS21075	COG0784	Response regulator, receiver
XC_RS21075	COG2205	protein histidine kinase activity
XC_RS21080	COG3459	Glycosyltransferase 36 associated
XC_RS21085	COG2211	Major facilitator Superfamily
XC_RS21090	COG3265	gluconokinase activity
XC_RS21095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_RS21115	COG2911	Protein conserved in bacteria
XC_RS21120	COG0729	surface antigen
XC_RS21135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XC_RS21140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XC_RS21140	COG0519	Catalyzes the synthesis of GMP from XMP
XC_RS21150	COG0805	protein transport
XC_RS21170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XC_RS21215	COG3661	Belongs to the glycosyl hydrolase 67 family
XC_RS21225	COG4948	Mandelate Racemase Muconate Lactonizing
XC_RS21235	COG1472	Belongs to the glycosyl hydrolase 3 family
XC_RS21240	COG0246	Mannitol dehydrogenase
XC_RS21280	COG3386	PFAM SMP-30 Gluconolaconase
XC_RS21295	COG3250	beta-galactosidase activity
XC_RS21305	COG3693	PFAM glycoside hydrolase, family 10
XC_RS21320	COG2211	Major facilitator Superfamily
XC_RS21390	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XC_RS21410	COG0210	DNA helicase
XC_RS21415	COG2963	transposase activity
XC_RS21420	COG2801	Transposase and inactivated derivatives
XC_RS21425	COG3002	Belongs to the UPF0753 family
XC_RS21480	COG3135	benzoate transporter
XC_RS21520	COG0730	response to heat
XC_RS21545	COG0302	gtp cyclohydrolase
XC_RS21560	COG1566	PFAM secretion protein HlyD family protein
XC_RS21570	COG1289	transmembrane transporter activity
XC_RS21575	COG0477	Major facilitator Superfamily
XC_RS21585	COG0583	DNA-binding transcription factor activity
XC_RS21590	COG4221	oxidoreductase activity
XC_RS21595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XC_RS21635	COG3039	Transposase
XC_RS21670	COG0564	pseudouridine synthase activity
XC_RS21685	COG1192	Involved in chromosome partitioning
XC_RS21720	COG1074	ATP-dependent DNA helicase activity
XC_RS21725	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XC_RS21760	COG1127	ABC transporter
XC_RS21765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XC_RS21770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XC_RS21785	COG2853	Lipoprotein
XC_RS21790	COG0386	Belongs to the glutathione peroxidase family
XC_RS21800	COG1322	Protein conserved in bacteria
XC_RS21805	COG0604	alcohol dehydrogenase
XC_RS21810	COG0583	DNA-binding transcription factor activity
XC_RS21825	COG0531	amino acid
XC_RS21835	COG4206	TonB-dependent receptor
XC_RS21845	COG2199	diguanylate cyclase activity
XC_RS21845	COG2203	Gaf domain
XC_RS21850	COG3835	regulator
XC_RS21855	COG1929	Belongs to the glycerate kinase type-1 family
XC_RS21860	COG2271	Major facilitator Superfamily
XC_RS21880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XC_RS21885	COG0861	Integral membrane protein TerC family
XC_RS21900	COG0584	glycerophosphoryl diester phosphodiesterase
XC_RS21910	COG0671	phosphoesterase, PA-phosphatase related
XC_RS21925	COG0726	polysaccharide deacetylase
XC_RS21970	COG3039	Transposase