locus-tag	class	description
XCC0004	COG0187	DNA topoisomerase II activity
XCC0006	COG0501	Belongs to the peptidase M48B family
XCC0014	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC0020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCC0021	COG0793	Belongs to the peptidase S41A family
XCC0022	COG4942	peptidase
XCC0024	COG2234	aminopeptidase activity
XCC0026	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCC0027	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCC0028	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCC0029	COG1064	alcohol dehydrogenase
XCC0031	COG0493	'glutamate synthase
XCC0032	COG0069	glutamate synthase activity
XCC0032	COG0070	glutamate synthase
XCC0032	COG0067	glutamate synthase
XCC0035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCC0037	COG1741	Belongs to the pirin family
XCC0038	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCC0039	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCC0043	COG0583	DNA-binding transcription factor activity
XCC0054	COG1205	dead DEAH box helicase
XCC0054	COG1111	helicase
XCC0055	COG3177	Filamentation induced by cAMP protein fic
XCC0056	COG1272	protein, Hemolysin III
XCC0060	COG2249	NAD(P)H dehydrogenase (quinone) activity
XCC0062	COG1733	regulation of RNA biosynthetic process
XCC0069	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XCC0070	COG3237	CsbD-like
XCC0079	COG0628	permease
XCC0080	COG0657	acetylesterase activity
XCC0082	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCC0083	COG0477	Major facilitator Superfamily
XCC0091	COG0714	Associated with various cellular activities
XCC0098	COG4772	TonB-dependent receptor
XCC0101	COG1012	belongs to the aldehyde dehydrogenase family
XCC0107	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCC0108	COG4585	Histidine kinase
XCC0109	COG2197	response regulator
XCC0114	COG3710	Transcriptional regulator
XCC0118	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCC0127	COG3039	Transposase
XCC0133	COG0366	Alpha amylase catalytic
XCC0134	COG0366	Alpha amylase catalytic
XCC0142	COG2755	lipolytic protein G-D-S-L family
XCC0144	COG0657	acetylesterase activity
XCC0144	COG2755	lipolytic protein G-D-S-L family
XCC0146	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCC0149	COG3507	Belongs to the glycosyl hydrolase 43 family
XCC0150	COG1609	Transcriptional regulator
XCC0152	COG1028	Short-chain dehydrogenase reductase Sdr
XCC0154	COG2755	lipolytic protein G-D-S-L family
XCC0156	COG3186	Phenylalanine-4-hydroxylase
XCC0157	COG1522	sequence-specific DNA binding
XCC0159	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCC0161	COG1119	ATPase activity
XCC0164	COG0517	IMP dehydrogenase activity
XCC0164	COG1125	glycine betaine transport
XCC0167	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCC0168	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCC0174	COG0489	protein tyrosine kinase activity
XCC0175	COG0588	phosphoglycerate mutase activity
XCC0177	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC0182	COG1881	PFAM PEBP family protein
XCC0185	COG0174	glutamine synthetase
XCC0186	COG0347	Belongs to the P(II) protein family
XCC0187	COG0004	ammonium transporteR
XCC0188	COG3852	Histidine kinase
XCC0189	COG2204	response regulator
XCC0190	COG2032	superoxide dismutase activity
XCC0191	COG2032	superoxide dismutase activity
XCC0192	COG0346	lactoylglutathione lyase activity
XCC0194	COG0183	Belongs to the thiolase family
XCC0202	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCC0206	COG0028	Belongs to the TPP enzyme family
XCC0209	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCC0212	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCC0213	COG3177	Filamentation induced by cAMP protein fic
XCC0216	COG0596	Alpha beta hydrolase
XCC0217	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCC0218	COG0318	PFAM AMP-dependent synthetase and ligase
XCC0219	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCC0222	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCC0225	COG0564	pseudouridine synthase activity
XCC0229	COG1446	asparaginase
XCC0230	COG0339	signal peptide processing
XCC0236	COG0583	DNA-binding transcription factor activity
XCC0237	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCC0238	COG2224	Isocitrate lyase
XCC0244	COG4770	biotin carboxylase activity
XCC0245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCC0246	COG1960	acyl-CoA dehydrogenase activity
XCC0259	COG0697	spore germination
XCC0261	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCC0263	COG1846	Transcriptional regulator
XCC0264	COG1764	response to oxidative stress
XCC0269	COG0656	L-ascorbic acid biosynthetic process
XCC0270	COG2130	NADP-dependent
XCC0273	COG1187	pseudouridine synthase activity
XCC0275	COG1643	Atp-dependent helicase
XCC0276	COG0840	transmembrane signaling receptor activity
XCC0277	COG4807	Protein conserved in bacteria
XCC0278	COG2351	hydroxyisourate hydrolase activity
XCC0279	COG2072	flavoprotein involved in K transport
XCC0283	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCC0289	COG3568	Endonuclease Exonuclease Phosphatase
XCC0290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC0293	COG1957	nucleoside hydrolase
XCC0295	COG2252	PERMEase
XCC0299	COG0084	hydrolase, TatD family'
XCC0301	COG0583	DNA-binding transcription factor activity
XCC0302	COG2814	Major facilitator Superfamily
XCC0307	COG1902	pentaerythritol trinitrate reductase activity
XCC0312	COG0300	oxidoreductase activity
XCC0314	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCC0315	COG0583	DNA-binding transcription factor activity
XCC0321	COG0702	epimerase
XCC0322	COG1733	regulation of RNA biosynthetic process
XCC0324	COG0840	transmembrane signaling receptor activity
XCC0348	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCC0359	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCC0364	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCC0365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCC0367	COG3485	protocatechuate 3,4-dioxygenase
XCC0368	COG3485	protocatechuate 3,4-dioxygenase
XCC0370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCC0371	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCC0373	COG1414	Transcriptional regulator
XCC0375	COG0657	acetylesterase activity
XCC0379	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCC0389	COG1040	competence protein
XCC0392	COG0582	viral genome integration into host DNA
XCC0394	COG4774	siderophore transport
XCC0395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCC0397	COG4206	TonB-dependent receptor
XCC0399	COG2963	transposase activity
XCC0402	COG3264	Mechanosensitive ion channel
XCC0402	COG1511	domain protein
XCC0403	COG1368	sulfuric ester hydrolase activity
XCC0404	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCC0405	COG2354	Protein conserved in bacteria
XCC0406	COG1649	PFAM Uncharacterised BCR, COG1649
XCC0410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCC0415	COG0702	epimerase
XCC0422	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCC0423	COG1028	Short-chain dehydrogenase reductase Sdr
XCC0425	COG0513	Belongs to the DEAD box helicase family
XCC0427	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCC0430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCC0433	COG3104	oligopeptide transport
XCC0437	COG2852	Protein conserved in bacteria
XCC0441	COG1320	monovalent cation:proton antiporter activity
XCC0442	COG2212	antiporter activity
XCC0444	COG0651	ATP synthesis coupled electron transport
XCC0445	COG1006	Multisubunit Na H antiporter MnhC subunit
XCC0446	COG2111	Na H antiporter
XCC0446	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCC0460	COG0436	Aminotransferase
XCC0462	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCC0468	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCC0489	COG2816	NAD+ diphosphatase activity
XCC0490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCC0495	COG2814	Major facilitator Superfamily
XCC0496	COG1289	transmembrane transporter activity
XCC0497	COG0151	Belongs to the GarS family
XCC0499	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCC0500	COG2267	carboxylic ester hydrolase activity
XCC0501	COG2453	phosphatase
XCC0501	COG0671	phosphoesterase, PA-phosphatase related
XCC0506	COG4589	Belongs to the CDS family
XCC0508	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCC0515	COG0439	Biotin carboxylase
XCC0517	COG0511	ligase activity, forming carbon-carbon bonds
XCC0520	COG1324	tolerance protein
XCC0521	COG2356	endonuclease I
XCC0524	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCC0526	COG1196	nuclear chromosome segregation
XCC0533	COG2963	transposase activity
XCC0542	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCC0544	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCC0545	COG1228	amidohydrolase
XCC0548	COG0356	it plays a direct role in the translocation of protons across the membrane
XCC0561	COG2963	transposase activity
XCC0565	COG0577	efflux transmembrane transporter activity
XCC0565	COG1136	(ABC) transporter
XCC0567	COG1136	(ABC) transporter
XCC0569	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCC0578	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCC0580	COG0339	signal peptide processing
XCC0586	COG1956	GAF domain-containing protein
XCC0587	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XCC0589	COG0720	synthase
XCC0590	COG0513	Belongs to the DEAD box helicase family
XCC0592	COG0625	glutathione transferase activity
XCC0598	COG0626	cystathionine gamma-synthase activity
XCC0603	COG0438	transferase activity, transferring glycosyl groups
XCC0606	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCC0609	COG3039	Transposase
XCC0610	COG2801	Transposase and inactivated derivatives
XCC0611	COG2963	transposase activity
XCC0616	COG0463	Glycosyl transferase, family 2
XCC0617	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XCC0618	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCC0618	COG0662	Cupin 2, conserved barrel domain protein
XCC0620	COG2086	electron transfer activity
XCC0621	COG1088	dTDP-glucose 4,6-dehydratase activity
XCC0625	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCC0625	COG0662	Cupin 2, conserved barrel domain protein
XCC0626	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCC0627	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCC0628	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCC0629	COG3754	Rhamnan synthesis protein F
XCC0633	COG3218	ABC-type transport auxiliary lipoprotein component
XCC0633	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCC0634	COG1127	ABC transporter
XCC0635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCC0641	COG1183	phosphatidylcholine synthase activity
XCC0651	COG0795	lipopolysaccharide-transporting ATPase activity
XCC0654	COG4974	Belongs to the 'phage' integrase family
XCC0655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCC0656	COG0047	phosphoribosylformylglycinamidine synthase activity
XCC0656	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCC0659	COG1404	Belongs to the peptidase S8 family
XCC0660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCC0661	COG1459	type II secretion system
XCC0662	COG2165	general secretion pathway protein
XCC0663	COG4970	Tfp pilus assembly protein FimT
XCC0664	COG2165	general secretion pathway protein
XCC0665	COG4795	General secretion pathway protein
XCC0666	COG3156	type II secretion system protein K
XCC0667	COG3166	PFAM Fimbrial assembly family protein
XCC0670	COG1450	Type ii and iii secretion system protein
XCC0672	COG2188	Transcriptional regulator
XCC0682	COG0457	Tetratricopeptide repeat
XCC0683	COG0457	Tetratricopeptide repeat
XCC0686	COG1393	Belongs to the ArsC family
XCC0687	COG0242	peptide deformylase activity
XCC0688	COG0488	(ABC) transporter
XCC0693	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCC0693	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCC0699	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCC0702	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCC0703	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCC0705	COG2205	protein histidine kinase activity
XCC0706	COG0745	RESPONSE REGULATOR receiver
XCC0708	COG0277	FAD linked oxidase domain protein
XCC0709	COG1988	membrane-bound metal-dependent
XCC0719	COG3116	cell division
XCC0722	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCC0727	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCC0728	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCC0733	COG0739	heme binding
XCC0736	COG0494	nUDIX hydrolase
XCC0739	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCC0742	COG3321	synthase
XCC0742	COG1028	Short-chain dehydrogenase reductase Sdr
XCC0742	COG0604	alcohol dehydrogenase
XCC0748	COG0366	Alpha amylase catalytic
XCC0754	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XCC0761	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XCC0763	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCC0765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCC0766	COG0667	Aldo Keto reductase
XCC0768	COG4771	TonB-dependent receptor
XCC0773	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCC0775	COG2175	clavaminate synthase activity
XCC0777	COG4181	ATPase activity
XCC0780	COG0642	Histidine kinase
XCC0782	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCC0789	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCC0795	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCC0796	COG2096	Adenosyltransferase
XCC0798	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCC0799	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCC0805	COG3384	dioxygenase
XCC0806	COG0583	DNA-binding transcription factor activity
XCC0807	COG0318	PFAM AMP-dependent synthetase and ligase
XCC0810	COG1024	Enoyl-CoA hydratase
XCC0814	COG3386	PFAM SMP-30 Gluconolaconase
XCC0819	COG0697	spore germination
XCC0825	COG5002	protein histidine kinase activity
XCC0825	COG2205	protein histidine kinase activity
XCC0825	COG0784	Response regulator, receiver
XCC0826	COG2197	response regulator
XCC0831	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCC0832	COG0583	DNA-binding transcription factor activity
XCC0833	COG3634	alkyl hydroperoxide reductase activity
XCC0835	COG2890	protein-(glutamine-N5) methyltransferase activity
XCC0839	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCC0839	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCC0840	COG0778	Nitroreductase
XCC0850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCC0851	COG1404	Belongs to the peptidase S8 family
XCC0852	COG1404	Belongs to the peptidase S8 family
XCC0853	COG1404	Belongs to the peptidase S8 family
XCC0854	COG1404	Belongs to the peptidase S8 family
XCC0855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCC0861	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCC0865	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCC0873	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCC0875	COG0193	aminoacyl-tRNA hydrolase activity
XCC0876	COG0012	GTP binding
XCC0883	COG0250	Participates in transcription elongation, termination and antitermination
XCC0888	COG0085	RNA polymerase activity
XCC0915	COG0201	protein transport
XCC0916	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XCC0922	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCC0924	COG0154	amidase activity
XCC0926	COG1217	gtp-binding protein TYPA
XCC0927	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCC0929	COG0625	glutathione transferase activity
XCC0933	COG1902	pentaerythritol trinitrate reductase activity
XCC0933	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCC0940	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCC0941	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCC0942	COG4208	sulfate ABC transporter
XCC0943	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCC0948	COG0406	alpha-ribazole phosphatase activity
XCC0950	COG0285	dihydrofolate synthase activity
XCC0954	COG2833	Protein of unknown function (DUF455)
XCC0955	COG3291	Pkd domain containing protein
XCC0957	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCC0958	COG0671	phosphoesterase, PA-phosphatase related
XCC0959	COG0438	transferase activity, transferring glycosyl groups
XCC0961	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCC0963	COG0745	RESPONSE REGULATOR receiver
XCC0964	COG4783	chaperone-mediated protein folding
XCC0967	COG0473	3-isopropylmalate dehydrogenase activity
XCC0974	COG0544	peptidyl-prolyl cis-trans isomerase activity
XCC0988	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCC0989	COG0631	protein serine/threonine phosphatase activity
XCC0992	COG0859	PFAM glycosyl transferase family 9
XCC0994	COG1234	tRNA 3'-trailer cleavage
XCC0998	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCC0999	COG0314	molybdopterin synthase activity
XCC1004	COG0537	adenosine 5'-monophosphoramidase activity
XCC1008	COG0714	Associated with various cellular activities
XCC1014	COG1399	metal-binding, possibly nucleic acid-binding protein
XCC1016	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCC1017	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCC1018	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1021	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCC1022	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCC1030	COG3829	transcription factor binding
XCC1034	COG3609	addiction module antidote protein, CC2985 family
XCC1039	COG2373	Large extracellular alpha-helical protein
XCC1044	COG4953	penicillin-binding protein 1C
XCC1046	COG0678	peroxiredoxin activity
XCC1050	COG0330	HflC and HflK could
XCC1051	COG0330	HflC and HflK could
XCC1054	COG0308	aminopeptidase N
XCC1057	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1058	COG1309	transcriptional regulator
XCC1076	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCC1078	COG3387	PFAM Glycoside hydrolase 15-related
XCC1079	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1081	COG3537	Alpha-1,2-mannosidase
XCC1082	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1091	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCC1092	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCC1093	COG2080	2 iron, 2 sulfur cluster binding
XCC1098	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCC1103	COG1297	OPT oligopeptide transporter protein
XCC1105	COG0823	Involved in the tonB-independent uptake of proteins
XCC1105	COG1506	peptidase
XCC1108	COG2207	Transcriptional regulator
XCC1108	COG1917	Cupin 2, conserved barrel domain protein
XCC1109	COG0753	catalase activity
XCC1110	COG0656	L-ascorbic acid biosynthetic process
XCC1113	COG2814	Major facilitator Superfamily
XCC1120	COG0745	RESPONSE REGULATOR receiver
XCC1121	COG5002	protein histidine kinase activity
XCC1124	COG2894	cell division
XCC1125	COG0850	regulation of cytokinetic process
XCC1127	COG4585	Histidine kinase
XCC1128	COG2197	response regulator
XCC1131	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCC1143	COG1595	DNA-templated transcription, initiation
XCC1145	COG1946	Acyl-CoA thioesterase
XCC1146	COG1024	Enoyl-CoA hydratase
XCC1147	COG0824	Thioesterase
XCC1148	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCC1154	COG0196	riboflavin kinase activity
XCC1157	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XCC1160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCC1161	COG1845	cytochrome c oxidase, subunit III
XCC1162	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCC1165	COG3152	Membrane
XCC1167	COG2207	Transcriptional regulator
XCC1168	COG0326	Molecular chaperone. Has ATPase activity
XCC1170	COG1902	pentaerythritol trinitrate reductase activity
XCC1171	COG1366	Belongs to the anti-sigma-factor antagonist family
XCC1172	COG1366	Belongs to the anti-sigma-factor antagonist family
XCC1173	COG2172	sigma factor antagonist activity
XCC1179	COG4771	TonB-dependent receptor
XCC1181	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCC1182	COG2205	protein histidine kinase activity
XCC1184	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCC1185	COG3850	Histidine kinase
XCC1185	COG4999	Histidine kinase
XCC1185	COG2205	protein histidine kinase activity
XCC1185	COG3437	response regulator, receiver
XCC1186	COG0784	Response regulator, receiver
XCC1186	COG4191	Histidine kinase
XCC1191	COG3534	alpha-L-arabinofuranosidase
XCC1193	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCC1194	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCC1197	COG2070	2-Nitropropane dioxygenase
XCC1203	COG0534	Mate efflux family protein
XCC1207	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCC1212	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCC1213	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1214	COG0436	Aminotransferase
XCC1215	COG1309	transcriptional regulator
XCC1219	COG5297	Belongs to the glycosyl hydrolase family 6
XCC1230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCC1248	COG3039	Transposase
XCC1256	COG3250	beta-galactosidase activity
XCC1257	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCC1259	COG3800	Transcriptional regulator
XCC1259	COG1396	sequence-specific DNA binding
XCC1261	COG1960	acyl-CoA dehydrogenase activity
XCC1262	COG1024	Enoyl-CoA hydratase
XCC1263	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XCC1269	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCC1270	COG0481	GTPase activity
XCC1279	COG2954	triphosphatase activity
XCC1280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCC1281	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCC1281	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCC1282	COG3046	protein related to deoxyribodipyrimidine photolyase
XCC1284	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCC1285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCC1286	COG1278	Cold shock
XCC1287	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCC1289	COG1201	RNA secondary structure unwinding
XCC1290	COG1793	dna ligase
XCC1291	COG1793	dna ligase
XCC1291	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCC1297	COG0183	Belongs to the thiolase family
XCC1301	COG1451	nucleotide metabolic process
XCC1302	COG5487	UPF0391 membrane protein
XCC1304	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCC1310	COG1047	Peptidyl-prolyl cis-trans
XCC1312	COG2824	Alkylphosphonate utilization operon protein PhnA
XCC1315	COG1902	pentaerythritol trinitrate reductase activity
XCC1316	COG2814	Major facilitator Superfamily
XCC1323	COG0392	lysyltransferase activity
XCC1323	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCC1325	COG0251	oxidation-reduction process
XCC1326	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCC1329	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCC1334	COG1595	DNA-templated transcription, initiation
XCC1337	COG2878	Part of a membrane complex involved in electron transport
XCC1342	COG0346	lactoylglutathione lyase activity
XCC1343	COG0833	amino acid
XCC1344	COG2040	homocysteine
XCC1346	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCC1351	COG1695	Transcriptional regulator
XCC1355	COG1981	membrane
XCC1366	COG0750	zinc metalloprotease
XCC1368	COG0575	Belongs to the CDS family
XCC1369	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCC1371	COG0528	UMP kinase activity
XCC1375	COG0052	Belongs to the universal ribosomal protein uS2 family
XCC1386	COG1393	Belongs to the ArsC family
XCC1388	COG0367	asparagine synthase
XCC1391	COG4774	siderophore transport
XCC1399	COG1566	PFAM secretion protein HlyD family protein
XCC1400	COG2814	Major facilitator Superfamily
XCC1406	COG3104	oligopeptide transport
XCC1412	COG0339	signal peptide processing
XCC1413	COG0386	Belongs to the glutathione peroxidase family
XCC1425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCC1426	COG0084	hydrolase, TatD family'
XCC1429	COG1960	acyl-CoA dehydrogenase activity
XCC1432	COG0367	asparagine synthase
XCC1434	COG0305	Participates in initiation and elongation during chromosome replication
XCC1435	COG0415	Belongs to the DNA photolyase family
XCC1437	COG0583	DNA-binding transcription factor activity
XCC1439	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCC1441	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1445	COG3706	GGDEF domain
XCC1453	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCC1456	COG2963	transposase activity
XCC1465	COG1404	Belongs to the peptidase S8 family
XCC1469	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCC1471	COG0497	DNA recombination
XCC1472	COG1420	regulation of RNA biosynthetic process
XCC1473	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCC1476	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCC1480	COG2274	protein secretion by the type I secretion system
XCC1481	COG0583	DNA-binding transcription factor activity
XCC1482	COG1132	(ABC) transporter
XCC1489	COG2850	peptidyl-arginine hydroxylation
XCC1493	COG1253	flavin adenine dinucleotide binding
XCC1499	COG1131	(ABC) transporter
XCC1500	COG1725	Transcriptional regulator
XCC1501	COG0386	Belongs to the glutathione peroxidase family
XCC1507	COG1609	Transcriptional regulator
XCC1509	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCC1511	COG1410	methionine synthase
XCC1511	COG0646	methionine synthase
XCC1512	COG1410	methionine synthase
XCC1512	COG0646	methionine synthase
XCC1513	COG2226	methyltransferase
XCC1514	COG1960	acyl-CoA dehydrogenase activity
XCC1517	COG0557	exoribonuclease II activity
XCC1519	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCC1523	COG0704	Plays a role in the regulation of phosphate uptake
XCC1525	COG0581	inorganic phosphate transmembrane transporter activity
XCC1526	COG0573	inorganic phosphate transmembrane transporter activity
XCC1527	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCC1531	COG0659	secondary active sulfate transmembrane transporter activity
XCC1532	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCC1534	COG1024	Enoyl-CoA hydratase
XCC1536	COG0494	nUDIX hydrolase
XCC1543	COG2264	protein methyltransferase activity
XCC1544	COG0488	(ABC) transporter
XCC1548	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCC1551	COG2925	Exonuclease
XCC1556	COG0288	reversible hydration of carbon dioxide
XCC1562	COG0316	Belongs to the HesB IscA family
XCC1569	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCC1571	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCC1575	COG4993	Dehydrogenase
XCC1577	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCC1588	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCC1590	COG0077	Prephenate dehydratase
XCC1590	COG1605	Chorismate mutase
XCC1592	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCC1595	COG0583	DNA-binding transcription factor activity
XCC1606	COG2963	transposase activity
XCC1607	COG2801	Transposase and inactivated derivatives
XCC1609	COG3039	Transposase
XCC1619	COG2003	Belongs to the UPF0758 family
XCC1627	COG2963	transposase activity
XCC1630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCC1634	COG2963	transposase activity
XCC1645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCC1654	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCC1655	COG4191	Histidine kinase
XCC1655	COG0784	Response regulator, receiver
XCC1658	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCC1662	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCC1669	COG3038	cytochrome b561
XCC1672	COG2244	polysaccharide biosynthetic process
XCC1678	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCC1679	COG0438	transferase activity, transferring glycosyl groups
XCC1680	COG0438	transferase activity, transferring glycosyl groups
XCC1684	COG1132	(ABC) transporter
XCC1685	COG0477	Major facilitator Superfamily
XCC1686	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCC1689	COG1253	flavin adenine dinucleotide binding
XCC1694	COG2134	cdp-diacylglycerol pyrophosphatase
XCC1705	COG2840	Smr protein MutS2
XCC1708	COG1238	metal cluster binding
XCC1711	COG1534	Rna-binding protein
XCC1713	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCC1714	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCC1717	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCC1718	COG1546	Belongs to the CinA family
XCC1719	COG4771	TonB-dependent receptor
XCC1721	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCC1724	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XCC1728	COG1741	Belongs to the pirin family
XCC1729	COG1741	Belongs to the pirin family
XCC1730	COG0583	DNA-binding transcription factor activity
XCC1735	COG0352	thiamine-phosphate diphosphorylase activity
XCC1735	COG0351	phosphomethylpyrimidine kinase
XCC1737	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCC1738	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCC1741	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCC1743	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCC1744	COG3734	2-keto-3-deoxy-galactonokinase
XCC1747	COG0800	Aldolase
XCC1755	COG1501	Belongs to the glycosyl hydrolase 31 family
XCC1757	COG1070	Carbohydrate kinase
XCC1759	COG0477	Major facilitator Superfamily
XCC1763	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCC1775	COG1472	Belongs to the glycosyl hydrolase 3 family
XCC1777	COG5001	Diguanylate cyclase
XCC1777	COG2203	Gaf domain
XCC1777	COG4251	negative regulation of phosphorylation
XCC1777	COG3706	GGDEF domain
XCC1778	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCC1779	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCC1782	COG0671	phosphoesterase, PA-phosphatase related
XCC1783	COG0477	Major facilitator Superfamily
XCC1785	COG1794	racemase activity, acting on amino acids and derivatives
XCC1786	COG0697	spore germination
XCC1791	COG1012	belongs to the aldehyde dehydrogenase family
XCC1796	COG2963	transposase activity
XCC1799	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCC1801	COG0083	homoserine kinase activity
XCC1803	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCC1805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCC1806	COG0124	histidyl-tRNA synthetase
XCC1808	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XCC1809	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XCC1810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCC1811	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCC1811	COG0131	Imidazoleglycerol-phosphate dehydratase
XCC1815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCC1815	COG0140	phosphoribosyl-ATP diphosphatase activity
XCC1821	COG0531	amino acid
XCC1822	COG0531	amino acid
XCC1825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCC1826	COG0277	FAD linked oxidase domain protein
XCC1833	COG1024	Enoyl-CoA hydratase
XCC1838	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCC1839	COG2258	MOSC domain
XCC1841	COG0505	Belongs to the CarA family
XCC1843	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCC1844	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCC1846	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCC1851	COG3279	Response regulator of the LytR AlgR family
XCC1852	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XCC1855	COG2205	protein histidine kinase activity
XCC1855	COG2198	Histidine kinase
XCC1855	COG0784	Response regulator, receiver
XCC1856	COG0784	Response regulator, receiver
XCC1856	COG2205	protein histidine kinase activity
XCC1856	COG2198	Histidine kinase
XCC1857	COG1024	Enoyl-CoA hydratase
XCC1858	COG0318	PFAM AMP-dependent synthetase and ligase
XCC1864	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCC1869	COG0840	transmembrane signaling receptor activity
XCC1871	COG0835	chemotaxis
XCC1873	COG0840	transmembrane signaling receptor activity
XCC1875	COG0840	transmembrane signaling receptor activity
XCC1876	COG0840	transmembrane signaling receptor activity
XCC1878	COG0840	transmembrane signaling receptor activity
XCC1879	COG0840	transmembrane signaling receptor activity
XCC1880	COG0840	transmembrane signaling receptor activity
XCC1881	COG0840	transmembrane signaling receptor activity
XCC1884	COG0840	transmembrane signaling receptor activity
XCC1886	COG0745	RESPONSE REGULATOR receiver
XCC1888	COG0835	chemotaxis
XCC1889	COG1192	Involved in chromosome partitioning
XCC1890	COG1360	Flagellar Motor Protein
XCC1891	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCC1903	COG2198	Histidine kinase
XCC1903	COG0784	Response regulator, receiver
XCC1903	COG0643	Histidine kinase
XCC1914	COG1684	flagellar biosynthetic protein fliR
XCC1915	COG1987	bacterial-type flagellum assembly
XCC1927	COG1677	Flagellar hook-basal body complex protein FliE
XCC1928	COG1216	Glycosyl transferase, family 2
XCC1928	COG0438	transferase activity, transferring glycosyl groups
XCC1934	COG2201	protein-glutamate methylesterase activity
XCC1940	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCC1941	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCC1942	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCC1944	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCC1944	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCC1948	COG4787	bacterial-type flagellum-dependent cell motility
XCC1950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCC1951	COG1558	bacterial-type flagellum-dependent cell motility
XCC1953	COG0784	Response regulator, receiver
XCC1953	COG0835	chemotaxis
XCC1957	COG4191	Histidine kinase
XCC1963	COG2915	High frequency lysogenization protein hflD homolog
XCC1967	COG0542	response to heat
XCC1971	COG0492	ferredoxin-NADP+ reductase activity
XCC1972	COG1674	ftsk spoiiie
XCC1976	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCC1977	COG0038	chloride channel
XCC1978	COG0183	Belongs to the thiolase family
XCC1979	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCC1979	COG1024	Enoyl-CoA hydratase
XCC1986	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCC1989	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCC1992	COG1028	Short-chain dehydrogenase reductase Sdr
XCC1993	COG2124	cytochrome p450
XCC1998	COG0708	Exodeoxyribonuclease III
XCC2000	COG0303	'Molybdopterin
XCC2001	COG0746	molybdenum cofactor guanylyltransferase activity
XCC2003	COG1648	precorrin-2 dehydrogenase activity
XCC2003	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCC2005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCC2006	COG2223	nitrite transmembrane transporter activity
XCC2007	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCC2009	COG0243	molybdopterin cofactor binding
XCC2013	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCC2015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCC2017	COG0579	oxidoreductase
XCC2020	COG3685	Protein conserved in bacteria
XCC2021	COG2201	protein-glutamate methylesterase activity
XCC2023	COG5001	Diguanylate cyclase
XCC2035	COG3590	peptidase
XCC2038	COG1999	signal sequence binding
XCC2041	COG1733	regulation of RNA biosynthetic process
XCC2045	COG1238	metal cluster binding
XCC2047	COG0840	transmembrane signaling receptor activity
XCC2053	COG0784	Response regulator, receiver
XCC2053	COG4191	Histidine kinase
XCC2055	COG3459	Glycosyltransferase 36 associated
XCC2082	COG0428	transporter
XCC2084	COG1530	ribonuclease E activity
XCC2090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCC2097	COG4644	lycopene metabolic process
XCC2098	COG2801	Transposase and inactivated derivatives
XCC2099	COG5599	Phosphatase
XCC2102	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCC2103	COG1061	Type III restriction enzyme res subunit
XCC2110	COG0582	viral genome integration into host DNA
XCC2114	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCC2117	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCC2122	COG0811	peptide transport
XCC2126	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCC2129	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCC2130	COG1053	succinate dehydrogenase
XCC2131	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCC2133	COG0354	folic acid binding
XCC2136	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCC2138	COG0363	glucosamine-6-phosphate deaminase activity
XCC2139	COG0129	dihydroxy-acid dehydratase activity
XCC2140	COG0800	Aldolase
XCC2153	COG5001	Diguanylate cyclase
XCC2154	COG2183	response to ionizing radiation
XCC2156	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCC2156	COG0723	plastoquinol--plastocyanin reductase activity
XCC2159	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCC2161	COG1183	phosphatidylcholine synthase activity
XCC2162	COG1028	Short-chain dehydrogenase reductase Sdr
XCC2165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XCC2167	COG0668	transmembrane transport
XCC2171	COG1914	H( )-stimulated, divalent metal cation uptake system
XCC2174	COG2814	Major facilitator Superfamily
XCC2177	COG1335	isochorismatase
XCC2180	COG2197	response regulator
XCC2187	COG0475	glutathione-regulated potassium exporter activity
XCC2187	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCC2188	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCC2191	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCC2194	COG0539	negative regulation of cytoplasmic translation
XCC2198	COG2957	Belongs to the agmatine deiminase family
XCC2199	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCC2204	COG0395	ABC-type sugar transport system, permease component
XCC2206	COG2182	Extracellular solute-binding protein
XCC2211	COG2350	Protein conserved in bacteria
XCC2212	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCC2213	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCC2214	COG1187	pseudouridine synthase activity
XCC2218	COG0436	Aminotransferase
XCC2230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCC2231	COG4988	ABC transporter
XCC2233	COG1294	oxidase, subunit
XCC2238	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XCC2243	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XCC2245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCC2246	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCC2247	COG0137	argininosuccinate synthase activity
XCC2249	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCC2252	COG2166	iron-sulfur cluster assembly
XCC2257	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCC2261	COG4302	ethanolamine ammonia-lyase activity
XCC2265	COG4677	pectinesterase activity
XCC2270	COG0402	S-adenosylhomocysteine deaminase activity
XCC2273	COG1509	lysine 2,3-aminomutase activity
XCC2274	COG5001	Diguanylate cyclase
XCC2274	COG3300	MHYT domain
XCC2277	COG0483	inositol monophosphate 1-phosphatase activity
XCC2278	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCC2281	COG0488	(ABC) transporter
XCC2282	COG0513	Belongs to the DEAD box helicase family
XCC2289	COG4681	YaeQ
XCC2290	COG2081	HI0933 family
XCC2291	COG5001	Diguanylate cyclase
XCC2291	COG3300	MHYT domain
XCC2294	COG1028	Short-chain dehydrogenase reductase Sdr
XCC2299	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCC2301	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCC2301	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCC2302	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCC2305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCC2314	COG0835	chemotaxis
XCC2315	COG0840	transmembrane signaling receptor activity
XCC2317	COG1201	RNA secondary structure unwinding
XCC2320	COG2969	positive regulation of protein catabolic process
XCC2321	COG0625	glutathione transferase activity
XCC2322	COG2857	Cytochrome c1
XCC2323	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCC2324	COG0723	plastoquinol--plastocyanin reductase activity
XCC2325	COG0741	lytic transglycosylase activity
XCC2329	COG1702	phosphate starvation-inducible protein PhoH
XCC2333	COG4535	Mg2 and Co2 transporter CorC
XCC2336	COG1012	belongs to the aldehyde dehydrogenase family
XCC2338	COG1177	transmembrane transport
XCC2339	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCC2340	COG3842	ATPase activity
XCC2347	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCC2348	COG0174	glutamine synthetase
XCC2349	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCC2351	COG2703	oxygen carrier activity
XCC2352	COG0477	Major facilitator Superfamily
XCC2354	COG0243	molybdopterin cofactor binding
XCC2356	COG2223	nitrite transmembrane transporter activity
XCC2357	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCC2359	COG2733	membrane
XCC2360	COG0784	Response regulator, receiver
XCC2360	COG2205	protein histidine kinase activity
XCC2360	COG5002	protein histidine kinase activity
XCC2362	COG0477	Major facilitator Superfamily
XCC2363	COG1335	isochorismatase
XCC2364	COG1609	Transcriptional regulator
XCC2364	COG2207	Transcriptional regulator
XCC2365	COG2902	Dehydrogenase
XCC2367	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCC2368	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCC2369	COG1609	Transcriptional regulator
XCC2370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCC2370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCC2371	COG1105	Belongs to the carbohydrate kinase PfkB family
XCC2372	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCC2372	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCC2375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCC2377	COG1862	Preprotein translocase
XCC2381	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCC2387	COG3291	Pkd domain containing protein
XCC2388	COG0405	Gamma-glutamyltransferase
XCC2389	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCC2392	COG0742	ribosomal rna small subunit methyltransferase
XCC2393	COG0326	Molecular chaperone. Has ATPase activity
XCC2395	COG4206	TonB-dependent receptor
XCC2397	COG0823	Involved in the tonB-independent uptake of proteins
XCC2397	COG1506	peptidase
XCC2398	COG3507	Belongs to the glycosyl hydrolase 43 family
XCC2400	COG4206	TonB-dependent receptor
XCC2406	COG0531	amino acid
XCC2409	COG0006	proline dipeptidase activity
XCC2411	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCC2415	COG3938	Belongs to the proline racemase family
XCC2417	COG0552	protein localization to endoplasmic reticulum
XCC2421	COG0784	Response regulator, receiver
XCC2421	COG4191	Histidine kinase
XCC2423	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCC2427	COG0322	excinuclease ABC activity
XCC2432	COG1960	acyl-CoA dehydrogenase activity
XCC2438	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCC2440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCC2445	COG0438	transferase activity, transferring glycosyl groups
XCC2446	COG2244	polysaccharide biosynthetic process
XCC2447	COG0438	transferase activity, transferring glycosyl groups
XCC2448	COG0438	transferase activity, transferring glycosyl groups
XCC2462	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCC2468	COG1082	Xylose isomerase domain protein TIM barrel
XCC2470	COG3039	Transposase
XCC2471	COG0366	Alpha amylase catalytic
XCC2472	COG2801	Transposase and inactivated derivatives
XCC2475	COG3702	type iv secretory pathway
XCC2479	COG2948	multi-organism process
XCC2483	COG3505	Type IV secretory pathway VirD4
XCC2486	COG4969	Belongs to the N-Me-Phe pilin family
XCC2495	COG4969	Belongs to the N-Me-Phe pilin family
XCC2496	COG1611	Belongs to the LOG family
XCC2498	COG2095	MarC family integral membrane protein
XCC2500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCC2511	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XCC2512	COG0195	Participates in both transcription termination and antitermination
XCC2515	COG1007	ATP synthesis coupled electron transport
XCC2519	COG0839	Belongs to the complex I subunit 6 family
XCC2523	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCC2524	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCC2528	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCC2532	COG4221	oxidoreductase activity
XCC2549	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCC2550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCC2553	COG2890	protein-(glutamine-N5) methyltransferase activity
XCC2558	COG0433	COG0433 Predicted ATPase
XCC2559	COG0494	nUDIX hydrolase
XCC2563	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCC2566	COG0412	Dienelactone hydrolase
XCC2571	COG0489	protein tyrosine kinase activity
XCC2574	COG3590	peptidase
XCC2575	COG3590	peptidase
XCC2579	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCC2580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCC2581	COG2311	Membrane
XCC2582	COG1047	Peptidyl-prolyl cis-trans
XCC2583	COG0791	NLP P60 protein
XCC2584	COG0791	NLP P60 protein
XCC2591	COG3284	Transcriptional regulator
XCC2592	COG4191	Histidine kinase
XCC2595	COG4106	trans-aconitate 2-methyltransferase activity
XCC2596	COG1301	dicarboxylic acid transport
XCC2597	COG1785	Belongs to the alkaline phosphatase family
XCC2600	COG0142	geranyltranstransferase activity
XCC2602	COG4104	PAAR repeat-containing protein
XCC2604	COG0312	modulator of DNA gyrase
XCC2606	COG0312	modulator of DNA gyrase
XCC2608	COG3164	Protein of unknown function
XCC2611	COG2968	Membrane
XCC2616	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCC2620	COG0495	leucyl-tRNA aminoacylation
XCC2622	COG3118	belongs to the thioredoxin family
XCC2624	COG2155	Conserved Protein
XCC2633	COG1132	(ABC) transporter
XCC2634	COG0475	glutathione-regulated potassium exporter activity
XCC2640	COG1187	pseudouridine synthase activity
XCC2641	COG5002	protein histidine kinase activity
XCC2641	COG5001	Diguanylate cyclase
XCC2661	COG1294	oxidase, subunit
XCC2662	COG1271	oxidase subunit
XCC2664	COG3383	formate dehydrogenase (NAD+) activity
XCC2666	COG1404	Belongs to the peptidase S8 family
XCC2671	COG0667	Aldo Keto reductase
XCC2672	COG2814	Major facilitator Superfamily
XCC2673	COG0583	DNA-binding transcription factor activity
XCC2676	COG2207	Transcriptional regulator
XCC2679	COG0667	Aldo Keto reductase
XCC2680	COG1309	transcriptional regulator
XCC2682	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCC2685	COG0735	belongs to the Fur family
XCC2692	COG4452	Inner membrane protein CreD
XCC2694	COG2205	protein histidine kinase activity
XCC2695	COG0745	RESPONSE REGULATOR receiver
XCC2696	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCC2698	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCC2700	COG2198	Histidine kinase
XCC2700	COG0643	Histidine kinase
XCC2701	COG0840	transmembrane signaling receptor activity
XCC2702	COG0835	chemotaxis
XCC2703	COG2202	Pas domain
XCC2703	COG2200	EAL domain
XCC2703	COG2199	diguanylate cyclase activity
XCC2704	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCC2706	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC2707	COG2963	transposase activity
XCC2709	COG3039	Transposase
XCC2710	COG3590	peptidase
XCC2714	COG1741	Belongs to the pirin family
XCC2717	COG1741	Belongs to the pirin family
XCC2718	COG1966	Carbon starvation protein
XCC2719	COG2879	small protein
XCC2725	COG0746	molybdenum cofactor guanylyltransferase activity
XCC2726	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCC2727	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCC2728	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCC2729	COG2080	2 iron, 2 sulfur cluster binding
XCC2730	COG0604	alcohol dehydrogenase
XCC2731	COG3706	GGDEF domain
XCC2731	COG4251	negative regulation of phosphorylation
XCC2731	COG5001	Diguanylate cyclase
XCC2731	COG2203	Gaf domain
XCC2733	COG1401	restriction endodeoxyribonuclease activity
XCC2735	COG0629	single-stranded DNA binding
XCC2736	COG0142	geranyltranstransferase activity
XCC2741	COG0527	aspartate kinase activity
XCC2742	COG0384	phenazine biosynthesis protein PhzF
XCC2743	COG0384	phenazine biosynthesis protein PhzF
XCC2745	COG1764	response to oxidative stress
XCC2749	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCC2750	COG0519	Catalyzes the synthesis of GMP from XMP
XCC2756	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCC2763	COG0693	protein deglycase activity
XCC2766	COG0719	Fe-S assembly protein
XCC2767	COG0396	ATPase activity
XCC2768	COG0719	Fe-S assembly protein
XCC2769	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCC2771	COG2146	nitrite reductase [NAD(P)H] activity
XCC2772	COG4774	siderophore transport
XCC2781	COG1555	photosystem II stabilization
XCC2782	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCC2785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCC2787	COG0628	permease
XCC2791	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCC2796	COG0271	Belongs to the BolA IbaG family
XCC2798	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCC2801	COG1137	ATPase activity
XCC2804	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCC2808	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCC2809	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCC2810	COG2239	Acts as a magnesium transporter
XCC2812	COG1294	oxidase, subunit
XCC2813	COG1271	oxidase subunit
XCC2814	COG1113	amino acid transport
XCC2818	COG2197	response regulator
XCC2819	COG0531	amino acid
XCC2833	COG0754	glutathionylspermidine amidase activity
XCC2838	COG1842	Phage shock protein A
XCC2845	COG0477	Major facilitator Superfamily
XCC2849	COG2353	YceI-like domain
XCC2853	COG1760	l-serine dehydratase
XCC2855	COG0527	aspartate kinase activity
XCC2855	COG0460	homoserine dehydrogenase
XCC2856	COG0626	cystathionine gamma-synthase activity
XCC2857	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCC2860	COG1272	protein, Hemolysin III
XCC2861	COG2982	Protein involved in outer membrane biogenesis
XCC2862	COG0516	GMP reductase activity
XCC2862	COG0517	IMP dehydrogenase activity
XCC2863	COG0463	Glycosyl transferase, family 2
XCC2865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCC2868	COG1309	transcriptional regulator
XCC2870	COG1960	acyl-CoA dehydrogenase activity
XCC2879	COG0330	HflC and HflK could
XCC2881	COG3956	TIGRFAM MazG family protein
XCC2882	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCC2883	COG0494	nUDIX hydrolase
XCC2885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCC2886	COG0837	glucose binding
XCC2889	COG1388	LysM domain
XCC2889	COG3858	chitin binding
XCC2890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCC2892	COG1472	Belongs to the glycosyl hydrolase 3 family
XCC2894	COG3537	Alpha-1,2-mannosidase
XCC2898	COG2963	transposase activity
XCC2903	COG3645	SOS response
XCC2905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCC2914	COG1446	asparaginase
XCC2915	COG2304	oxidoreductase activity
XCC2916	COG1595	DNA-templated transcription, initiation
XCC2921	COG0784	Response regulator, receiver
XCC2921	COG0643	Histidine kinase
XCC2921	COG2198	Histidine kinase
XCC2922	COG0840	transmembrane signaling receptor activity
XCC2923	COG0835	chemotaxis
XCC2926	COG0189	ligase activity
XCC2928	COG1397	ADP-ribosylglycohydrolase
XCC2930	COG1199	ATP-dependent helicase activity
XCC2932	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCC2933	COG1215	transferase activity, transferring glycosyl groups
XCC2936	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCC2945	COG1643	Atp-dependent helicase
XCC2946	COG0783	Belongs to the Dps family
XCC2947	COG0514	ATP-dependent DNA helicase (RecQ)
XCC2951	COG1187	pseudouridine synthase activity
XCC2955	COG0583	DNA-binding transcription factor activity
XCC2964	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XCC2969	COG4695	Portal protein
XCC3015	COG0602	queuosine metabolic process
XCC3017	COG2885	chlorophyll binding
XCC3020	COG0848	biopolymer transport protein
XCC3022	COG0824	Thioesterase
XCC3023	COG2255	four-way junction helicase activity
XCC3034	COG0477	Major facilitator Superfamily
XCC3038	COG2755	lipolytic protein G-D-S-L family
XCC3038	COG0657	acetylesterase activity
XCC3042	COG0488	(ABC) transporter
XCC3048	COG4651	solute:proton antiporter activity
XCC3048	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCC3050	COG4772	TonB-dependent receptor
XCC3052	COG4264	IucA IucC family
XCC3053	COG2814	Major facilitator Superfamily
XCC3054	COG4264	IucA IucC family
XCC3055	COG0019	diaminopimelate decarboxylase activity
XCC3057	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCC3062	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCC3063	COG1797	cobyrinic acid a,c-diamide synthase activity
XCC3067	COG4206	TonB-dependent receptor
XCC3070	COG0542	response to heat
XCC3071	COG1116	anion transmembrane transporter activity
XCC3080	COG1877	trehalose-phosphatase activity
XCC3081	COG3387	PFAM Glycoside hydrolase 15-related
XCC3084	COG0840	transmembrane signaling receptor activity
XCC3087	COG1496	oxidoreductase activity
XCC3088	COG0564	pseudouridine synthase activity
XCC3089	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCC3091	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCC3091	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCC3100	COG1459	type II secretion system
XCC3101	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCC3107	COG0745	RESPONSE REGULATOR receiver
XCC3113	COG2963	transposase activity
XCC3120	COG5001	Diguanylate cyclase
XCC3123	COG2963	transposase activity
XCC3124	COG2801	Transposase and inactivated derivatives
XCC3134	COG2963	transposase activity
XCC3135	COG2801	Transposase and inactivated derivatives
XCC3136	COG2963	transposase activity
XCC3138	COG2963	transposase activity
XCC3142	COG0583	DNA-binding transcription factor activity
XCC3143	COG1396	sequence-specific DNA binding
XCC3146	COG0582	viral genome integration into host DNA
XCC3152	COG3273	potassium ion transport
XCC3152	COG0471	metal ion transport
XCC3159	COG1609	Transcriptional regulator
XCC3160	COG5297	Belongs to the glycosyl hydrolase family 6
XCC3162	COG3250	beta-galactosidase activity
XCC3163	COG4948	Mandelate Racemase Muconate Lactonizing
XCC3164	COG2272	Belongs to the type-B carboxylesterase lipase family
XCC3165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCC3166	COG1115	amino acid carrier protein
XCC3168	COG0308	aminopeptidase N
XCC3169	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCC3170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCC3171	COG0529	Catalyzes the synthesis of activated sulfate
XCC3171	COG2895	sulfate adenylyltransferase (ATP) activity
XCC3173	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCC3174	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCC3178	COG0784	Response regulator, receiver
XCC3178	COG2198	Histidine kinase
XCC3178	COG2205	protein histidine kinase activity
XCC3184	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCC3185	COG3588	fructose-bisphosphate aldolase
XCC3186	COG0469	pyruvate kinase activity
XCC3192	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCC3195	COG3047	cAMP biosynthetic process
XCC3197	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCC3197	COG3453	Protein conserved in bacteria
XCC3200	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCC3201	COG4149	molybdate abc transporter
XCC3210	COG1376	ErfK ybiS ycfS ynhG family protein
XCC3211	COG0739	heme binding
XCC3212	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3213	COG0583	DNA-binding transcription factor activity
XCC3215	COG4773	Receptor
XCC3216	COG4773	Receptor
XCC3217	COG2963	transposase activity
XCC3219	COG0596	Alpha beta hydrolase
XCC3220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCC3221	COG1301	dicarboxylic acid transport
XCC3223	COG2304	oxidoreductase activity
XCC3227	COG0714	Associated with various cellular activities
XCC3233	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCC3238	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCC3240	COG2721	sulfolactate sulfo-lyase activity
XCC3243	COG2271	Major facilitator Superfamily
XCC3246	COG0583	DNA-binding transcription factor activity
XCC3247	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCC3250	COG1561	YicC-like family, N-terminal region
XCC3252	COG0346	lactoylglutathione lyase activity
XCC3254	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCC3259	COG0006	proline dipeptidase activity
XCC3263	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCC3267	COG2912	Transglutaminase-like superfamily
XCC3268	COG1773	rubredoxin
XCC3275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCC3282	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCC3283	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCC3285	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3287	COG0671	phosphoesterase, PA-phosphatase related
XCC3288	COG3781	membrane
XCC3290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCC3303	COG3039	Transposase
XCC3306	COG2963	transposase activity
XCC3312	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCC3314	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCC3318	COG3710	Transcriptional regulator
XCC3320	COG1506	peptidase
XCC3320	COG0823	Involved in the tonB-independent uptake of proteins
XCC3320	COG4946	Tricorn protease homolog
XCC3321	COG0840	transmembrane signaling receptor activity
XCC3322	COG0405	Gamma-glutamyltransferase
XCC3329	COG2226	methyltransferase
XCC3331	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCC3333	COG5001	Diguanylate cyclase
XCC3333	COG3300	MHYT domain
XCC3335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCC3336	COG1538	Outer membrane efflux protein
XCC3337	COG1519	Transferase
XCC3338	COG1560	Kdo2-lipid A biosynthetic process
XCC3348	COG4191	Histidine kinase
XCC3349	COG2197	response regulator
XCC3351	COG0642	Histidine kinase
XCC3354	COG2851	Citrate transporter
XCC3355	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3356	COG1609	Transcriptional regulator
XCC3357	COG2211	Major facilitator Superfamily
XCC3364	COG0436	Aminotransferase
XCC3368	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCC3372	COG0402	S-adenosylhomocysteine deaminase activity
XCC3382	COG1307	EDD domain protein, DegV family
XCC3384	COG0697	spore germination
XCC3386	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCC3387	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCC3391	COG0583	DNA-binding transcription factor activity
XCC3395	COG2205	protein histidine kinase activity
XCC3400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCC3402	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCC3403	COG1012	belongs to the aldehyde dehydrogenase family
XCC3410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCC3411	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCC3412	COG1609	Transcriptional regulator
XCC3414	COG2188	Transcriptional regulator
XCC3419	COG4795	General secretion pathway protein
XCC3420	COG2165	general secretion pathway protein
XCC3423	COG1459	type II secretion system
XCC3431	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3433	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCC3434	COG4191	Histidine kinase
XCC3435	COG0784	Response regulator, receiver
XCC3436	COG4251	negative regulation of phosphorylation
XCC3437	COG2823	Periplasmic or secreted lipoprotein
XCC3438	COG0673	inositol 2-dehydrogenase activity
XCC3439	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCC3446	COG1051	belongs to the nudix hydrolase family
XCC3446	COG1056	cytidyltransferase-related domain
XCC3456	COG1686	Belongs to the peptidase S11 family
XCC3457	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCC3458	COG2951	lytic endotransglycosylase activity
XCC3464	COG2963	transposase activity
XCC3466	COG0772	Belongs to the SEDS family
XCC3469	COG1792	Involved in formation and maintenance of cell shape
XCC3470	COG1077	Cell shape determining protein MreB Mrl
XCC3471	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCC3472	COG3284	Transcriptional regulator
XCC3475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCC3481	COG2963	transposase activity
XCC3485	COG0308	aminopeptidase N
XCC3486	COG5001	Diguanylate cyclase
XCC3486	COG3300	MHYT domain
XCC3488	COG2226	methyltransferase
XCC3495	COG2963	transposase activity
XCC3501	COG2832	Protein of unknown function (DUF454)
XCC3503	COG0436	Aminotransferase
XCC3506	COG1505	serine-type exopeptidase activity
XCC3513	COG3275	phosphorelay sensor kinase activity
XCC3516	COG0471	metal ion transport
XCC3516	COG3273	potassium ion transport
XCC3519	COG3706	GGDEF domain
XCC3520	COG0659	secondary active sulfate transmembrane transporter activity
XCC3521	COG5297	Belongs to the glycosyl hydrolase family 6
XCC3521	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCC3522	COG0840	transmembrane signaling receptor activity
XCC3523	COG5001	Diguanylate cyclase
XCC3523	COG5002	protein histidine kinase activity
XCC3523	COG3447	MASE1 domain protein
XCC3533	COG1113	amino acid transport
XCC3534	COG5297	Belongs to the glycosyl hydrolase family 6
XCC3535	COG4305	rare lipoprotein A
XCC3538	COG0697	spore germination
XCC3545	COG1959	2 iron, 2 sulfur cluster binding
XCC3548	COG1506	peptidase
XCC3548	COG0823	Involved in the tonB-independent uptake of proteins
XCC3549	COG2409	Drug exporters of the RND superfamily
XCC3561	COG0435	Glutathione S-transferase
XCC3572	COG2963	transposase activity
XCC3573	COG2801	Transposase and inactivated derivatives
XCC3575	COG2963	transposase activity
XCC3581	COG2963	transposase activity
XCC3582	COG2801	Transposase and inactivated derivatives
XCC3583	COG2963	transposase activity
XCC3585	COG3039	Transposase
XCC3587	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCC3591	COG3386	PFAM SMP-30 Gluconolaconase
XCC3594	COG3712	iron ion homeostasis
XCC3601	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCC3606	COG2353	YceI-like domain
XCC3617	COG1802	Transcriptional regulator
XCC3629	COG2011	ABC-type metal ion transport system permease component
XCC3631	COG0697	spore germination
XCC3637	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCC3638	COG1187	pseudouridine synthase activity
XCC3639	COG2813	Specifically methylates the guanine in position
XCC3643	COG5002	protein histidine kinase activity
XCC3659	COG0842	Transport permease protein
XCC3660	COG1131	(ABC) transporter
XCC3661	COG0025	NhaP-type Na H and K H
XCC3662	COG3795	YCII-related domain
XCC3663	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCC3664	COG1573	uracil-dna glycosylase
XCC3666	COG3384	dioxygenase
XCC3667	COG0583	DNA-binding transcription factor activity
XCC3669	COG0667	Aldo Keto reductase
XCC3671	COG3590	peptidase
XCC3674	COG0531	amino acid
XCC3677	COG2972	Histidine kinase
XCC3680	COG1335	isochorismatase
XCC3681	COG3685	Protein conserved in bacteria
XCC3682	COG3685	Protein conserved in bacteria
XCC3683	COG3546	catalase activity
XCC3689	COG2204	response regulator
XCC3691	COG1271	oxidase subunit
XCC3692	COG1294	oxidase, subunit
XCC3695	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3696	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCC3700	COG1132	(ABC) transporter
XCC3703	COG1063	alcohol dehydrogenase
XCC3709	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCC3720	COG0251	oxidation-reduction process
XCC3724	COG0667	Aldo Keto reductase
XCC3725	COG0583	DNA-binding transcription factor activity
XCC3729	COG3706	GGDEF domain
XCC3729	COG2203	Gaf domain
XCC3729	COG4251	negative regulation of phosphorylation
XCC3729	COG5001	Diguanylate cyclase
XCC3732	COG2963	transposase activity
XCC3733	COG2801	Transposase and inactivated derivatives
XCC3736	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCC3738	COG1560	Kdo2-lipid A biosynthetic process
XCC3740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCC3747	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCC3747	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCC3749	COG0242	peptide deformylase activity
XCC3750	COG1652	LysM domain
XCC3751	COG0758	DNA mediated transformation
XCC3755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCC3755	COG1754	DNA topoisomerase type I activity
XCC3759	COG5001	Diguanylate cyclase
XCC3759	COG4251	negative regulation of phosphorylation
XCC3759	COG3706	GGDEF domain
XCC3759	COG2203	Gaf domain
XCC3760	COG1028	Short-chain dehydrogenase reductase Sdr
XCC3761	COG0616	signal peptide processing
XCC3762	COG0534	Mate efflux family protein
XCC3765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCC3766	COG0625	glutathione transferase activity
XCC3769	COG1252	NADH dehydrogenase
XCC3770	COG2860	membrane
XCC3771	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCC3773	COG3437	response regulator, receiver
XCC3774	COG2177	Part of the ABC transporter FtsEX involved in
XCC3775	COG2884	Cell division ATP-binding protein ftsE
XCC3777	COG3118	belongs to the thioredoxin family
XCC3778	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCC3786	COG1473	amidohydrolase
XCC3787	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCC3792	COG4941	Belongs to the sigma-70 factor family
XCC3793	COG5383	Protein conserved in bacteria
XCC3801	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCC3802	COG3409	Peptidoglycan-binding domain 1 protein
XCC3802	COG3501	Rhs element vgr protein
XCC3805	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCC3807	COG4948	Mandelate Racemase Muconate Lactonizing
XCC3809	COG0531	amino acid
XCC3812	COG4682	membrane
XCC3813	COG2133	pyrroloquinoline quinone binding
XCC3815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCC3818	COG1610	YqeY-like protein
XCC3819	COG1295	ribonuclease BN
XCC3820	COG0358	DNA primase activity
XCC3830	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCC3833	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCC3842	COG0739	heme binding
XCC3846	COG0708	Exodeoxyribonuclease III
XCC3849	COG1192	Involved in chromosome partitioning
XCC3850	COG1475	DNA binding
XCC3854	COG0463	Glycosyl transferase, family 2
XCC3859	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCC3864	COG4221	oxidoreductase activity
XCC3865	COG2755	lipolytic protein G-D-S-L family
XCC3865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCC3867	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCC3868	COG1166	arginine decarboxylase activity
XCC3873	COG2960	long-chain fatty acid transporting porin activity
XCC3874	COG0606	chelatase, subunit chli
XCC3877	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCC3883	COG1690	Belongs to the RtcB family
XCC3890	COG1090	epimerase
XCC3891	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCC3894	COG0642	Histidine kinase
XCC3898	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCC3903	COG1011	Hydrolase
XCC3904	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCC3909	COG2197	response regulator
XCC3910	COG4585	Histidine kinase
XCC3912	COG1136	(ABC) transporter
XCC3917	COG0697	spore germination
XCC3923	COG0180	Tryptophanyl-tRNA synthetase
XCC3924	COG3237	CsbD-like
XCC3938	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCC3938	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCC3939	COG3228	Belongs to the MtfA family
XCC3945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCC3950	COG1199	ATP-dependent helicase activity
XCC3962	COG0625	glutathione transferase activity
XCC3969	COG4555	ABC transporter
XCC3971	COG1476	TRANSCRIPTIONal
XCC3974	COG1230	cation diffusion facilitator family transporter
XCC3976	COG1131	(ABC) transporter
XCC3977	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCC3978	COG0842	Transport permease protein
XCC3980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCC3982	COG1607	acyl-coa hydrolase
XCC3985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCC3986	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCC3988	COG0045	succinate-CoA ligase (ADP-forming) activity
XCC3988	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCC3988	COG1042	CoA-binding domain protein
XCC3990	COG2239	Acts as a magnesium transporter
XCC3993	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCC3994	COG3387	PFAM Glycoside hydrolase 15-related
XCC3997	COG3100	YcgL domain-containing protein
XCC3998	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCC4000	COG0463	Glycosyl transferase, family 2
XCC4003	COG1028	Short-chain dehydrogenase reductase Sdr
XCC4009	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XCC4012	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCC4026	COG0210	DNA helicase
XCC4028	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC4030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCC4032	COG2159	amidohydrolase
XCC4043	COG2091	lysine biosynthetic process via aminoadipic acid
XCC4055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCC4057	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCC4058	COG3162	membrane
XCC4064	COG3507	Belongs to the glycosyl hydrolase 43 family
XCC4067	COG1028	Short-chain dehydrogenase reductase Sdr
XCC4068	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCC4069	COG4948	Mandelate Racemase Muconate Lactonizing
XCC4070	COG3254	rhamnose metabolic process
XCC4071	COG0738	Major facilitator superfamily
XCC4072	COG1414	Transcriptional regulator
XCC4076	COG0784	Response regulator, receiver
XCC4076	COG2205	protein histidine kinase activity
XCC4077	COG3459	Glycosyltransferase 36 associated
XCC4078	COG2211	Major facilitator Superfamily
XCC4079	COG3265	gluconokinase activity
XCC4080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCC4084	COG2911	Protein conserved in bacteria
XCC4085	COG0729	surface antigen
XCC4088	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCC4089	COG0519	Catalyzes the synthesis of GMP from XMP
XCC4089	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCC4091	COG0805	protein transport
XCC4095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCC4102	COG3661	Belongs to the glycosyl hydrolase 67 family
XCC4104	COG4948	Mandelate Racemase Muconate Lactonizing
XCC4106	COG1472	Belongs to the glycosyl hydrolase 3 family
XCC4107	COG0246	Mannitol dehydrogenase
XCC4113	COG3386	PFAM SMP-30 Gluconolaconase
XCC4116	COG3250	beta-galactosidase activity
XCC4118	COG3693	PFAM glycoside hydrolase, family 10
XCC4121	COG2211	Major facilitator Superfamily
XCC4128	COG2937	Belongs to the GPAT DAPAT family
XCC4135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCC4139	COG0210	DNA helicase
XCC4140	COG2963	transposase activity
XCC4141	COG2801	Transposase and inactivated derivatives
XCC4142	COG3002	Belongs to the UPF0753 family
XCC4145	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCC4153	COG3135	benzoate transporter
XCC4157	COG0676	glucose-6-phosphate 1-epimerase activity
XCC4161	COG0730	response to heat
XCC4166	COG0302	gtp cyclohydrolase
XCC4169	COG1566	PFAM secretion protein HlyD family protein
XCC4171	COG1289	transmembrane transporter activity
XCC4172	COG0477	Major facilitator Superfamily
XCC4174	COG0583	DNA-binding transcription factor activity
XCC4175	COG4221	oxidoreductase activity
XCC4176	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCC4184	COG3039	Transposase
XCC4189	COG0564	pseudouridine synthase activity
XCC4191	COG1192	Involved in chromosome partitioning
XCC4199	COG1074	ATP-dependent DNA helicase activity
XCC4200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCC4207	COG1127	ABC transporter
XCC4208	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCC4209	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCC4212	COG2853	Lipoprotein
XCC4213	COG0386	Belongs to the glutathione peroxidase family
XCC4215	COG1322	Protein conserved in bacteria
XCC4216	COG0604	alcohol dehydrogenase
XCC4217	COG0583	DNA-binding transcription factor activity
XCC4220	COG0531	amino acid
XCC4222	COG4206	TonB-dependent receptor
XCC4224	COG3706	GGDEF domain
XCC4225	COG3835	regulator
XCC4226	COG1929	Belongs to the glycerate kinase type-1 family
XCC4227	COG2271	Major facilitator Superfamily
XCC4231	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCC4232	COG0861	Integral membrane protein TerC family
XCC4234	COG0584	glycerophosphoryl diester phosphodiesterase
XCC4236	COG0671	phosphoesterase, PA-phosphatase related
XCC4239	COG0726	polysaccharide deacetylase
XCC4240	COG0706	membrane insertase activity