locus-tag	class	description
XCCCN12_RS00025	COG0187	DNA topoisomerase II activity
XCCCN12_RS00035	COG0501	Belongs to the peptidase M48B family
XCCCN12_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS00110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN12_RS00115	COG0793	Belongs to the peptidase S41A family
XCCCN12_RS00120	COG4942	peptidase
XCCCN12_RS00130	COG2234	aminopeptidase activity
XCCCN12_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN12_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN12_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN12_RS00160	COG1064	alcohol dehydrogenase
XCCCN12_RS00170	COG0493	'glutamate synthase
XCCCN12_RS00175	COG0067	glutamate synthase
XCCCN12_RS00175	COG0069	glutamate synthase activity
XCCCN12_RS00175	COG0070	glutamate synthase
XCCCN12_RS00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCCCN12_RS00200	COG1741	Belongs to the pirin family
XCCCN12_RS00205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCCCN12_RS00225	COG0583	DNA-binding transcription factor activity
XCCCN12_RS00285	COG1205	dead DEAH box helicase
XCCCN12_RS00285	COG1111	helicase
XCCCN12_RS00290	COG3177	Filamentation induced by cAMP protein fic
XCCCN12_RS00295	COG1272	protein, Hemolysin III
XCCCN12_RS00375	COG3237	CsbD-like
XCCCN12_RS00425	COG0628	permease
XCCCN12_RS00430	COG0657	acetylesterase activity
XCCCN12_RS00440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN12_RS00445	COG0477	Major facilitator Superfamily
XCCCN12_RS00485	COG0714	Associated with various cellular activities
XCCCN12_RS00530	COG4772	TonB-dependent receptor
XCCCN12_RS00545	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN12_RS00575	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCCCN12_RS00580	COG4585	Histidine kinase
XCCCN12_RS00585	COG2197	response regulator
XCCCN12_RS00615	COG3710	Transcriptional regulator
XCCCN12_RS00635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN12_RS00665	COG4916	TIR domain
XCCCN12_RS00675	COG1192	Involved in chromosome partitioning
XCCCN12_RS00725	COG3039	Transposase
XCCCN12_RS00735	COG0366	Alpha amylase catalytic
XCCCN12_RS00740	COG0366	Alpha amylase catalytic
XCCCN12_RS00785	COG2755	lipolytic protein G-D-S-L family
XCCCN12_RS00795	COG0657	acetylesterase activity
XCCCN12_RS00795	COG2755	lipolytic protein G-D-S-L family
XCCCN12_RS00805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCCCN12_RS00820	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN12_RS00825	COG1609	Transcriptional regulator
XCCCN12_RS00835	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS00845	COG2755	lipolytic protein G-D-S-L family
XCCCN12_RS00855	COG3186	Phenylalanine-4-hydroxylase
XCCCN12_RS00860	COG1522	sequence-specific DNA binding
XCCCN12_RS00875	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCCCN12_RS00885	COG1119	ATPase activity
XCCCN12_RS00900	COG1125	glycine betaine transport
XCCCN12_RS00900	COG0517	IMP dehydrogenase activity
XCCCN12_RS00915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN12_RS00920	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCCCN12_RS00950	COG0489	protein tyrosine kinase activity
XCCCN12_RS00955	COG0588	phosphoglycerate mutase activity
XCCCN12_RS00965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS00990	COG1881	PFAM PEBP family protein
XCCCN12_RS01010	COG0174	glutamine synthetase
XCCCN12_RS01015	COG0347	Belongs to the P(II) protein family
XCCCN12_RS01020	COG0004	ammonium transporteR
XCCCN12_RS01025	COG3852	Histidine kinase
XCCCN12_RS01030	COG2204	response regulator
XCCCN12_RS01040	COG2032	superoxide dismutase activity
XCCCN12_RS01045	COG2032	superoxide dismutase activity
XCCCN12_RS01050	COG0346	lactoylglutathione lyase activity
XCCCN12_RS01060	COG0183	Belongs to the thiolase family
XCCCN12_RS01100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCCCN12_RS01120	COG0028	Belongs to the TPP enzyme family
XCCCN12_RS01135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCCCN12_RS01150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN12_RS01155	COG3177	Filamentation induced by cAMP protein fic
XCCCN12_RS01160	COG0596	Alpha beta hydrolase
XCCCN12_RS01165	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCCCN12_RS01175	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN12_RS01180	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS01195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN12_RS01235	COG3540	Alkaline phosphatase
XCCCN12_RS01305	COG2159	amidohydrolase
XCCCN12_RS01315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCCCN12_RS01320	COG0583	DNA-binding transcription factor activity
XCCCN12_RS01325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS01335	COG0210	DNA helicase
XCCCN12_RS01410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCCCN12_RS01425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XCCCN12_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS01470	COG0463	Glycosyl transferase, family 2
XCCCN12_RS01480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCCCN12_RS01500	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN12_RS01505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN12_RS01520	COG2239	Acts as a magnesium transporter
XCCCN12_RS01530	COG1042	CoA-binding domain protein
XCCCN12_RS01530	COG0045	succinate-CoA ligase (ADP-forming) activity
XCCCN12_RS01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCCCN12_RS01540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN12_RS01550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCCCN12_RS01555	COG0716	FMN binding
XCCCN12_RS01565	COG1607	acyl-coa hydrolase
XCCCN12_RS01580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCCCN12_RS01590	COG0842	Transport permease protein
XCCCN12_RS01595	COG1131	(ABC) transporter
XCCCN12_RS01600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN12_RS01610	COG1230	cation diffusion facilitator family transporter
XCCCN12_RS01625	COG1476	TRANSCRIPTIONal
XCCCN12_RS01635	COG4555	ABC transporter
XCCCN12_RS01670	COG0625	glutathione transferase activity
XCCCN12_RS01735	COG1199	ATP-dependent helicase activity
XCCCN12_RS01765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN12_RS01805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCCCN12_RS01805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCCCN12_RS01880	COG3237	CsbD-like
XCCCN12_RS01885	COG0180	Tryptophanyl-tRNA synthetase
XCCCN12_RS01910	COG0697	spore germination
XCCCN12_RS01935	COG1136	(ABC) transporter
XCCCN12_RS01955	COG4585	Histidine kinase
XCCCN12_RS01960	COG2197	response regulator
XCCCN12_RS01980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCCCN12_RS01985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN12_RS02010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN12_RS02030	COG0642	Histidine kinase
XCCCN12_RS02045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN12_RS02050	COG1090	epimerase
XCCCN12_RS02090	COG1690	Belongs to the RtcB family
XCCCN12_RS02125	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCCCN12_RS02140	COG0606	chelatase, subunit chli
XCCCN12_RS02145	COG2960	long-chain fatty acid transporting porin activity
XCCCN12_RS02170	COG1166	arginine decarboxylase activity
XCCCN12_RS02190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCCCN12_RS02190	COG2755	lipolytic protein G-D-S-L family
XCCCN12_RS02195	COG4221	oxidoreductase activity
XCCCN12_RS02220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCCCN12_RS02245	COG0463	Glycosyl transferase, family 2
XCCCN12_RS02265	COG1475	DNA binding
XCCCN12_RS02270	COG1192	Involved in chromosome partitioning
XCCCN12_RS02285	COG0708	Exodeoxyribonuclease III
XCCCN12_RS02310	COG0739	heme binding
XCCCN12_RS02355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCCCN12_RS02370	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCCCN12_RS02420	COG0358	DNA primase activity
XCCCN12_RS02425	COG1295	ribonuclease BN
XCCCN12_RS02430	COG1610	YqeY-like protein
XCCCN12_RS02445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCCCN12_RS02455	COG2133	pyrroloquinoline quinone binding
XCCCN12_RS02460	COG4682	membrane
XCCCN12_RS02475	COG0531	amino acid
XCCCN12_RS02485	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN12_RS02495	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCCCN12_RS02510	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN12_RS02510	COG3501	Rhs element vgr protein
XCCCN12_RS02515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCCCN12_RS02555	COG5383	Protein conserved in bacteria
XCCCN12_RS02560	COG4941	Belongs to the sigma-70 factor family
XCCCN12_RS02600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN12_RS02605	COG1473	amidohydrolase
XCCCN12_RS02650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCCCN12_RS02655	COG3118	belongs to the thioredoxin family
XCCCN12_RS02665	COG2884	Cell division ATP-binding protein ftsE
XCCCN12_RS02670	COG2177	Part of the ABC transporter FtsEX involved in
XCCCN12_RS02675	COG3437	response regulator, receiver
XCCCN12_RS02685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN12_RS02690	COG2860	membrane
XCCCN12_RS02695	COG1252	NADH dehydrogenase
XCCCN12_RS02715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCCCN12_RS02730	COG0534	Mate efflux family protein
XCCCN12_RS02735	COG0616	signal peptide processing
XCCCN12_RS02745	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS02750	COG3706	GGDEF domain
XCCCN12_RS02750	COG4251	negative regulation of phosphorylation
XCCCN12_RS02750	COG2203	Gaf domain
XCCCN12_RS02750	COG5001	Diguanylate cyclase
XCCCN12_RS02770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCCCN12_RS02770	COG1754	DNA topoisomerase type I activity
XCCCN12_RS02790	COG0758	DNA mediated transformation
XCCCN12_RS02795	COG1652	LysM domain
XCCCN12_RS02800	COG0242	peptide deformylase activity
XCCCN12_RS02810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCCCN12_RS02810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCCCN12_RS02845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCCCN12_RS02855	COG1560	Kdo2-lipid A biosynthetic process
XCCCN12_RS02865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCCCN12_RS02905	COG4251	negative regulation of phosphorylation
XCCCN12_RS02905	COG3706	GGDEF domain
XCCCN12_RS02905	COG2203	Gaf domain
XCCCN12_RS02905	COG5001	Diguanylate cyclase
XCCCN12_RS02925	COG0583	DNA-binding transcription factor activity
XCCCN12_RS02930	COG0667	Aldo Keto reductase
XCCCN12_RS02950	COG0251	oxidation-reduction process
XCCCN12_RS03010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN12_RS03050	COG1063	alcohol dehydrogenase
XCCCN12_RS03065	COG1132	(ABC) transporter
XCCCN12_RS03085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCCCN12_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS03105	COG1294	oxidase, subunit
XCCCN12_RS03110	COG1271	oxidase subunit
XCCCN12_RS03120	COG2204	response regulator
XCCCN12_RS03150	COG3546	catalase activity
XCCCN12_RS03155	COG3685	Protein conserved in bacteria
XCCCN12_RS03160	COG3685	Protein conserved in bacteria
XCCCN12_RS03165	COG1335	isochorismatase
XCCCN12_RS03190	COG2972	Histidine kinase
XCCCN12_RS03205	COG0531	amino acid
XCCCN12_RS03220	COG3590	peptidase
XCCCN12_RS03230	COG0667	Aldo Keto reductase
XCCCN12_RS03240	COG0583	DNA-binding transcription factor activity
XCCCN12_RS03245	COG3384	dioxygenase
XCCCN12_RS03260	COG1573	uracil-dna glycosylase
XCCCN12_RS03265	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCCCN12_RS03270	COG3795	YCII-related domain
XCCCN12_RS03275	COG0025	NhaP-type Na H and K H
XCCCN12_RS03280	COG1131	(ABC) transporter
XCCCN12_RS03285	COG0842	Transport permease protein
XCCCN12_RS03370	COG5002	protein histidine kinase activity
XCCCN12_RS03390	COG2813	Specifically methylates the guanine in position
XCCCN12_RS03395	COG1187	pseudouridine synthase activity
XCCCN12_RS03400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCCCN12_RS03430	COG0697	spore germination
XCCCN12_RS03440	COG2011	ABC-type metal ion transport system permease component
XCCCN12_RS03470	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN12_RS03480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN12_RS03485	COG1228	amidohydrolase
XCCCN12_RS03500	COG0356	it plays a direct role in the translocation of protons across the membrane
XCCCN12_RS03565	COG4191	Histidine kinase
XCCCN12_RS03585	COG0577	efflux transmembrane transporter activity
XCCCN12_RS03590	COG1136	(ABC) transporter
XCCCN12_RS03600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN12_RS03655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCCCN12_RS03660	COG0339	signal peptide processing
XCCCN12_RS03690	COG1956	GAF domain-containing protein
XCCCN12_RS03705	COG0720	synthase
XCCCN12_RS03710	COG0513	Belongs to the DEAD box helicase family
XCCCN12_RS03725	COG0625	glutathione transferase activity
XCCCN12_RS03755	COG0626	cystathionine gamma-synthase activity
XCCCN12_RS03780	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS03795	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCCCN12_RS03820	COG0463	Glycosyl transferase, family 2
XCCCN12_RS03830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN12_RS03830	COG0662	Cupin 2, conserved barrel domain protein
XCCCN12_RS03840	COG2086	electron transfer activity
XCCCN12_RS03865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCCCN12_RS03865	COG0662	Cupin 2, conserved barrel domain protein
XCCCN12_RS03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCCCN12_RS03915	COG3218	ABC-type transport auxiliary lipoprotein component
XCCCN12_RS03915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN12_RS03920	COG1127	ABC transporter
XCCCN12_RS03925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN12_RS03950	COG1183	phosphatidylcholine synthase activity
XCCCN12_RS04020	COG0795	lipopolysaccharide-transporting ATPase activity
XCCCN12_RS04035	COG4974	Belongs to the 'phage' integrase family
XCCCN12_RS04040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN12_RS04045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCCCN12_RS04045	COG0047	phosphoribosylformylglycinamidine synthase activity
XCCCN12_RS04060	COG1404	Belongs to the peptidase S8 family
XCCCN12_RS04065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN12_RS04070	COG1459	type II secretion system
XCCCN12_RS04080	COG2165	general secretion pathway protein
XCCCN12_RS04085	COG4970	Tfp pilus assembly protein FimT
XCCCN12_RS04090	COG2165	general secretion pathway protein
XCCCN12_RS04095	COG4795	General secretion pathway protein
XCCCN12_RS04100	COG3156	type II secretion system protein K
XCCCN12_RS04105	COG3166	PFAM Fimbrial assembly family protein
XCCCN12_RS04120	COG1450	Type ii and iii secretion system protein
XCCCN12_RS04130	COG2188	Transcriptional regulator
XCCCN12_RS04190	COG0457	Tetratricopeptide repeat
XCCCN12_RS04205	COG1393	Belongs to the ArsC family
XCCCN12_RS04210	COG0242	peptide deformylase activity
XCCCN12_RS04215	COG0488	(ABC) transporter
XCCCN12_RS04240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN12_RS04240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCCCN12_RS04270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCCCN12_RS04295	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCCCN12_RS04300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCCCN12_RS04310	COG2205	protein histidine kinase activity
XCCCN12_RS04315	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS04325	COG0277	FAD linked oxidase domain protein
XCCCN12_RS04330	COG1988	membrane-bound metal-dependent
XCCCN12_RS04390	COG3116	cell division
XCCCN12_RS04405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCCCN12_RS04430	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN12_RS04435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCCCN12_RS04460	COG0739	heme binding
XCCCN12_RS04475	COG0494	nUDIX hydrolase
XCCCN12_RS04490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN12_RS04505	COG0604	alcohol dehydrogenase
XCCCN12_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS04505	COG3321	synthase
XCCCN12_RS04550	COG0366	Alpha amylase catalytic
XCCCN12_RS04650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCCCN12_RS04665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCCCN12_RS04675	COG0667	Aldo Keto reductase
XCCCN12_RS04690	COG4771	TonB-dependent receptor
XCCCN12_RS04715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCCCN12_RS04725	COG2175	clavaminate synthase activity
XCCCN12_RS04735	COG4181	ATPase activity
XCCCN12_RS04750	COG0642	Histidine kinase
XCCCN12_RS04760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCCCN12_RS04795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCCCN12_RS04825	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCCCN12_RS04830	COG2096	Adenosyltransferase
XCCCN12_RS04840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN12_RS04845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN12_RS04875	COG3384	dioxygenase
XCCCN12_RS04880	COG0583	DNA-binding transcription factor activity
XCCCN12_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN12_RS04895	COG1024	Enoyl-CoA hydratase
XCCCN12_RS04915	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN12_RS04945	COG0697	spore germination
XCCCN12_RS04975	COG2205	protein histidine kinase activity
XCCCN12_RS04975	COG0784	Response regulator, receiver
XCCCN12_RS04975	COG5002	protein histidine kinase activity
XCCCN12_RS04980	COG2197	response regulator
XCCCN12_RS05005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN12_RS05010	COG0583	DNA-binding transcription factor activity
XCCCN12_RS05015	COG3634	alkyl hydroperoxide reductase activity
XCCCN12_RS05025	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN12_RS05050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN12_RS05050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCCCN12_RS05055	COG0778	Nitroreductase
XCCCN12_RS05120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCCCN12_RS05125	COG1404	Belongs to the peptidase S8 family
XCCCN12_RS05135	COG1404	Belongs to the peptidase S8 family
XCCCN12_RS05140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCCCN12_RS05170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN12_RS05190	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCCCN12_RS05240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCCCN12_RS05250	COG0193	aminoacyl-tRNA hydrolase activity
XCCCN12_RS05255	COG0012	GTP binding
XCCCN12_RS05285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XCCCN12_RS05290	COG0250	Participates in transcription elongation, termination and antitermination
XCCCN12_RS05295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCCCN12_RS05365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCCCN12_RS05450	COG0201	protein transport
XCCCN12_RS05485	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCCCN12_RS05495	COG0154	amidase activity
XCCCN12_RS05505	COG1217	gtp-binding protein TYPA
XCCCN12_RS05510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCCCN12_RS05520	COG0625	glutathione transferase activity
XCCCN12_RS05545	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCCCN12_RS05545	COG1902	pentaerythritol trinitrate reductase activity
XCCCN12_RS05580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCCCN12_RS05585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCCCN12_RS05590	COG4208	sulfate ABC transporter
XCCCN12_RS05595	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCCCN12_RS05620	COG0406	alpha-ribazole phosphatase activity
XCCCN12_RS05635	COG0285	dihydrofolate synthase activity
XCCCN12_RS05655	COG2833	Protein of unknown function (DUF455)
XCCCN12_RS05660	COG3291	Pkd domain containing protein
XCCCN12_RS05670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCCCN12_RS05675	COG0671	phosphoesterase, PA-phosphatase related
XCCCN12_RS05680	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS05690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCCCN12_RS05700	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS05705	COG4783	chaperone-mediated protein folding
XCCCN12_RS05720	COG0473	3-isopropylmalate dehydrogenase activity
XCCCN12_RS05825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCCCN12_RS05830	COG0631	protein serine/threonine phosphatase activity
XCCCN12_RS05845	COG0859	PFAM glycosyl transferase family 9
XCCCN12_RS05855	COG1234	tRNA 3'-trailer cleavage
XCCCN12_RS05875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCCCN12_RS05880	COG0314	molybdopterin synthase activity
XCCCN12_RS05915	COG4191	Histidine kinase
XCCCN12_RS05915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XCCCN12_RS05950	COG2003	Belongs to the UPF0758 family
XCCCN12_RS06015	COG0537	adenosine 5'-monophosphoramidase activity
XCCCN12_RS06035	COG0714	Associated with various cellular activities
XCCCN12_RS06065	COG1399	metal-binding, possibly nucleic acid-binding protein
XCCCN12_RS06075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN12_RS06080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCCCN12_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS06100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCCCN12_RS06105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCCCN12_RS06200	COG3829	transcription factor binding
XCCCN12_RS06220	COG3609	addiction module antidote protein, CC2985 family
XCCCN12_RS06255	COG2373	Large extracellular alpha-helical protein
XCCCN12_RS06280	COG4953	penicillin-binding protein 1C
XCCCN12_RS06290	COG0678	peroxiredoxin activity
XCCCN12_RS06310	COG0330	HflC and HflK could
XCCCN12_RS06315	COG0330	HflC and HflK could
XCCCN12_RS06330	COG0308	aminopeptidase N
XCCCN12_RS06390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN12_RS06425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN12_RS06440	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN12_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS06455	COG3537	Alpha-1,2-mannosidase
XCCCN12_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS06505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN12_RS06510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN12_RS06515	COG2080	2 iron, 2 sulfur cluster binding
XCCCN12_RS06540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN12_RS06565	COG1297	OPT oligopeptide transporter protein
XCCCN12_RS06575	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN12_RS06575	COG1506	peptidase
XCCCN12_RS06600	COG2207	Transcriptional regulator
XCCCN12_RS06600	COG1917	Cupin 2, conserved barrel domain protein
XCCCN12_RS06615	COG0753	catalase activity
XCCCN12_RS06620	COG0656	L-ascorbic acid biosynthetic process
XCCCN12_RS06650	COG2814	Major facilitator Superfamily
XCCCN12_RS06670	COG2194	sulfuric ester hydrolase activity
XCCCN12_RS06685	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS06690	COG5002	protein histidine kinase activity
XCCCN12_RS06705	COG2894	cell division
XCCCN12_RS06720	COG4585	Histidine kinase
XCCCN12_RS06725	COG2197	response regulator
XCCCN12_RS06750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN12_RS06810	COG1595	DNA-templated transcription, initiation
XCCCN12_RS06830	COG1946	Acyl-CoA thioesterase
XCCCN12_RS06835	COG1024	Enoyl-CoA hydratase
XCCCN12_RS06840	COG0824	Thioesterase
XCCCN12_RS06845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCCCN12_RS06875	COG0196	riboflavin kinase activity
XCCCN12_RS06905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCCCN12_RS06910	COG1845	cytochrome c oxidase, subunit III
XCCCN12_RS06915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCCCN12_RS06935	COG3152	Membrane
XCCCN12_RS06950	COG2207	Transcriptional regulator
XCCCN12_RS06955	COG0326	Molecular chaperone. Has ATPase activity
XCCCN12_RS06965	COG1902	pentaerythritol trinitrate reductase activity
XCCCN12_RS06970	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN12_RS06975	COG1366	Belongs to the anti-sigma-factor antagonist family
XCCCN12_RS06980	COG2172	sigma factor antagonist activity
XCCCN12_RS07005	COG4771	TonB-dependent receptor
XCCCN12_RS07015	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCCCN12_RS07020	COG2205	protein histidine kinase activity
XCCCN12_RS07030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN12_RS07035	COG2205	protein histidine kinase activity
XCCCN12_RS07035	COG3437	response regulator, receiver
XCCCN12_RS07035	COG3850	Histidine kinase
XCCCN12_RS07035	COG4999	Histidine kinase
XCCCN12_RS07040	COG0784	Response regulator, receiver
XCCCN12_RS07040	COG4191	Histidine kinase
XCCCN12_RS07070	COG3534	alpha-L-arabinofuranosidase
XCCCN12_RS07080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN12_RS07085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCCCN12_RS07100	COG2070	2-Nitropropane dioxygenase
XCCCN12_RS07130	COG0534	Mate efflux family protein
XCCCN12_RS07150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCCCN12_RS07170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN12_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS07180	COG0436	Aminotransferase
XCCCN12_RS07185	COG1309	transcriptional regulator
XCCCN12_RS07205	COG3039	Transposase
XCCCN12_RS07235	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN12_RS07290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCCCN12_RS07505	COG3250	beta-galactosidase activity
XCCCN12_RS07510	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCCCN12_RS07520	COG3800	Transcriptional regulator
XCCCN12_RS07520	COG1396	sequence-specific DNA binding
XCCCN12_RS07530	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS07535	COG1024	Enoyl-CoA hydratase
XCCCN12_RS07570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN12_RS07620	COG2954	triphosphatase activity
XCCCN12_RS07625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCCCN12_RS07630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN12_RS07630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCCCN12_RS07635	COG3046	protein related to deoxyribodipyrimidine photolyase
XCCCN12_RS07645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCCCN12_RS07650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCCCN12_RS07655	COG1278	Cold shock
XCCCN12_RS07660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCCCN12_RS07670	COG1201	RNA secondary structure unwinding
XCCCN12_RS07675	COG1793	dna ligase
XCCCN12_RS07685	COG1793	dna ligase
XCCCN12_RS07685	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCCCN12_RS07720	COG0183	Belongs to the thiolase family
XCCCN12_RS07740	COG1451	nucleotide metabolic process
XCCCN12_RS07745	COG5487	UPF0391 membrane protein
XCCCN12_RS07755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCCCN12_RS07800	COG1047	Peptidyl-prolyl cis-trans
XCCCN12_RS07810	COG2824	Alkylphosphonate utilization operon protein PhnA
XCCCN12_RS07835	COG1902	pentaerythritol trinitrate reductase activity
XCCCN12_RS07840	COG2814	Major facilitator Superfamily
XCCCN12_RS07875	COG0392	lysyltransferase activity
XCCCN12_RS07875	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCCCN12_RS07885	COG0251	oxidation-reduction process
XCCCN12_RS07890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN12_RS07905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCCCN12_RS07930	COG1595	DNA-templated transcription, initiation
XCCCN12_RS07945	COG2878	Part of a membrane complex involved in electron transport
XCCCN12_RS07970	COG0346	lactoylglutathione lyase activity
XCCCN12_RS07980	COG0833	amino acid
XCCCN12_RS07985	COG2040	homocysteine
XCCCN12_RS07995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN12_RS08025	COG1695	Transcriptional regulator
XCCCN12_RS08050	COG1981	membrane
XCCCN12_RS08105	COG0750	zinc metalloprotease
XCCCN12_RS08115	COG0575	Belongs to the CDS family
XCCCN12_RS08120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCCCN12_RS08130	COG0528	UMP kinase activity
XCCCN12_RS08205	COG1393	Belongs to the ArsC family
XCCCN12_RS08220	COG0367	asparagine synthase
XCCCN12_RS08235	COG4774	siderophore transport
XCCCN12_RS08280	COG1566	PFAM secretion protein HlyD family protein
XCCCN12_RS08285	COG2814	Major facilitator Superfamily
XCCCN12_RS08315	COG3104	oligopeptide transport
XCCCN12_RS08350	COG0339	signal peptide processing
XCCCN12_RS08355	COG0386	Belongs to the glutathione peroxidase family
XCCCN12_RS08415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCCCN12_RS08420	COG0084	hydrolase, TatD family'
XCCCN12_RS08435	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08450	COG0367	asparagine synthase
XCCCN12_RS08460	COG0305	Participates in initiation and elongation during chromosome replication
XCCCN12_RS08465	COG0415	Belongs to the DNA photolyase family
XCCCN12_RS08480	COG0583	DNA-binding transcription factor activity
XCCCN12_RS08495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN12_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS08525	COG3706	GGDEF domain
XCCCN12_RS08545	COG1404	Belongs to the peptidase S8 family
XCCCN12_RS08565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN12_RS08575	COG0497	DNA recombination
XCCCN12_RS08580	COG1420	regulation of RNA biosynthetic process
XCCCN12_RS08585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCCCN12_RS08605	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCCCN12_RS08630	COG2274	protein secretion by the type I secretion system
XCCCN12_RS08635	COG0583	DNA-binding transcription factor activity
XCCCN12_RS08640	COG1132	(ABC) transporter
XCCCN12_RS08675	COG2850	peptidyl-arginine hydroxylation
XCCCN12_RS08695	COG1253	flavin adenine dinucleotide binding
XCCCN12_RS08725	COG1131	(ABC) transporter
XCCCN12_RS08730	COG1725	Transcriptional regulator
XCCCN12_RS08740	COG0386	Belongs to the glutathione peroxidase family
XCCCN12_RS08770	COG1609	Transcriptional regulator
XCCCN12_RS08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN12_RS08790	COG1410	methionine synthase
XCCCN12_RS08790	COG0646	methionine synthase
XCCCN12_RS08795	COG1410	methionine synthase
XCCCN12_RS08795	COG0646	methionine synthase
XCCCN12_RS08800	COG2226	methyltransferase
XCCCN12_RS08805	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08815	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08820	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08825	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08830	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08835	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08840	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS08855	COG0557	exoribonuclease II activity
XCCCN12_RS08870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN12_RS08890	COG0704	Plays a role in the regulation of phosphate uptake
XCCCN12_RS08900	COG0581	inorganic phosphate transmembrane transporter activity
XCCCN12_RS08905	COG0573	inorganic phosphate transmembrane transporter activity
XCCCN12_RS08910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCCCN12_RS08935	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN12_RS08940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCCCN12_RS08950	COG1024	Enoyl-CoA hydratase
XCCCN12_RS08960	COG0494	nUDIX hydrolase
XCCCN12_RS08995	COG2264	protein methyltransferase activity
XCCCN12_RS09000	COG0488	(ABC) transporter
XCCCN12_RS09020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCCCN12_RS09035	COG2925	Exonuclease
XCCCN12_RS09060	COG0288	reversible hydration of carbon dioxide
XCCCN12_RS09085	COG0017	Asparaginyl-tRNA synthetase
XCCCN12_RS09090	COG0316	Belongs to the HesB IscA family
XCCCN12_RS09125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN12_RS09135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCCCN12_RS09155	COG4993	Dehydrogenase
XCCCN12_RS09165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCCCN12_RS09220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCCCN12_RS09230	COG0077	Prephenate dehydratase
XCCCN12_RS09230	COG1605	Chorismate mutase
XCCCN12_RS09240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCCCN12_RS09255	COG0583	DNA-binding transcription factor activity
XCCCN12_RS09330	COG2003	Belongs to the UPF0758 family
XCCCN12_RS09385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XCCCN12_RS09435	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCCCN12_RS09440	COG0784	Response regulator, receiver
XCCCN12_RS09440	COG4191	Histidine kinase
XCCCN12_RS09455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCCCN12_RS09475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCCCN12_RS09510	COG3038	cytochrome b561
XCCCN12_RS09525	COG2244	polysaccharide biosynthetic process
XCCCN12_RS09555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN12_RS09560	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS09565	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS09585	COG1132	(ABC) transporter
XCCCN12_RS09590	COG0477	Major facilitator Superfamily
XCCCN12_RS09595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCCCN12_RS09610	COG1253	flavin adenine dinucleotide binding
XCCCN12_RS09640	COG2134	cdp-diacylglycerol pyrophosphatase
XCCCN12_RS09700	COG2840	Smr protein MutS2
XCCCN12_RS09715	COG1238	metal cluster binding
XCCCN12_RS09730	COG1534	Rna-binding protein
XCCCN12_RS09740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCCCN12_RS09745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCCCN12_RS09760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCCCN12_RS09765	COG1546	Belongs to the CinA family
XCCCN12_RS09775	COG4771	TonB-dependent receptor
XCCCN12_RS09790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCCCN12_RS09825	COG1741	Belongs to the pirin family
XCCCN12_RS09830	COG0583	DNA-binding transcription factor activity
XCCCN12_RS09855	COG0351	phosphomethylpyrimidine kinase
XCCCN12_RS09855	COG0352	thiamine-phosphate diphosphorylase activity
XCCCN12_RS09865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCCCN12_RS09870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCCCN12_RS09885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN12_RS09895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCCCN12_RS09900	COG3734	2-keto-3-deoxy-galactonokinase
XCCCN12_RS09915	COG0800	Aldolase
XCCCN12_RS09960	COG1501	Belongs to the glycosyl hydrolase 31 family
XCCCN12_RS09970	COG1070	Carbohydrate kinase
XCCCN12_RS09980	COG0477	Major facilitator Superfamily
XCCCN12_RS10000	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN12_RS10055	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN12_RS10065	COG2203	Gaf domain
XCCCN12_RS10065	COG3706	GGDEF domain
XCCCN12_RS10065	COG4251	negative regulation of phosphorylation
XCCCN12_RS10065	COG5001	Diguanylate cyclase
XCCCN12_RS10070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN12_RS10075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCCCN12_RS10090	COG0671	phosphoesterase, PA-phosphatase related
XCCCN12_RS10095	COG0477	Major facilitator Superfamily
XCCCN12_RS10100	COG1794	racemase activity, acting on amino acids and derivatives
XCCCN12_RS10105	COG0697	spore germination
XCCCN12_RS10130	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN12_RS10190	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCCCN12_RS10210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XCCCN12_RS10220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN12_RS10250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCCCN12_RS10250	COG0131	Imidazoleglycerol-phosphate dehydratase
XCCCN12_RS10270	COG0140	phosphoribosyl-ATP diphosphatase activity
XCCCN12_RS10270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCCCN12_RS10310	COG0531	amino acid
XCCCN12_RS10315	COG0531	amino acid
XCCCN12_RS10330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCCCN12_RS10335	COG0277	FAD linked oxidase domain protein
XCCCN12_RS10370	COG1024	Enoyl-CoA hydratase
XCCCN12_RS10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN12_RS10400	COG2258	MOSC domain
XCCCN12_RS10410	COG0505	Belongs to the CarA family
XCCCN12_RS10420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCCCN12_RS10425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCCCN12_RS10435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCCCN12_RS10460	COG3279	Response regulator of the LytR AlgR family
XCCCN12_RS10480	COG0784	Response regulator, receiver
XCCCN12_RS10480	COG2205	protein histidine kinase activity
XCCCN12_RS10480	COG2198	Histidine kinase
XCCCN12_RS10485	COG2205	protein histidine kinase activity
XCCCN12_RS10485	COG2198	Histidine kinase
XCCCN12_RS10485	COG0784	Response regulator, receiver
XCCCN12_RS10490	COG1024	Enoyl-CoA hydratase
XCCCN12_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
XCCCN12_RS10525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN12_RS10555	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10565	COG0835	chemotaxis
XCCCN12_RS10590	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10600	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10605	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10610	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10615	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10620	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10625	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10635	COG0840	transmembrane signaling receptor activity
XCCCN12_RS10645	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS10655	COG0835	chemotaxis
XCCCN12_RS10660	COG1192	Involved in chromosome partitioning
XCCCN12_RS10665	COG1360	Flagellar Motor Protein
XCCCN12_RS10670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCCCN12_RS10790	COG0643	Histidine kinase
XCCCN12_RS10790	COG0784	Response regulator, receiver
XCCCN12_RS10790	COG2198	Histidine kinase
XCCCN12_RS10845	COG1684	flagellar biosynthetic protein fliR
XCCCN12_RS10850	COG1987	bacterial-type flagellum assembly
XCCCN12_RS10920	COG1677	Flagellar hook-basal body complex protein FliE
XCCCN12_RS10960	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS10970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN12_RS10990	COG2201	protein-glutamate methylesterase activity
XCCCN12_RS11020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCCCN12_RS11025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN12_RS11030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCCCN12_RS11040	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCCCN12_RS11040	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCCCN12_RS11065	COG4787	bacterial-type flagellum-dependent cell motility
XCCCN12_RS11075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCCCN12_RS11080	COG1558	bacterial-type flagellum-dependent cell motility
XCCCN12_RS11090	COG0835	chemotaxis
XCCCN12_RS11090	COG0784	Response regulator, receiver
XCCCN12_RS11110	COG4191	Histidine kinase
XCCCN12_RS11145	COG2915	High frequency lysogenization protein hflD homolog
XCCCN12_RS11165	COG0542	response to heat
XCCCN12_RS11185	COG0492	ferredoxin-NADP+ reductase activity
XCCCN12_RS11190	COG1674	ftsk spoiiie
XCCCN12_RS11210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCCCN12_RS11215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCCCN12_RS11220	COG0183	Belongs to the thiolase family
XCCCN12_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCCCN12_RS11225	COG1024	Enoyl-CoA hydratase
XCCCN12_RS11260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN12_RS11275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCCCN12_RS11290	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS11295	COG2124	cytochrome p450
XCCCN12_RS11320	COG0708	Exodeoxyribonuclease III
XCCCN12_RS11330	COG0303	'Molybdopterin
XCCCN12_RS11335	COG0746	molybdenum cofactor guanylyltransferase activity
XCCCN12_RS11345	COG1648	precorrin-2 dehydrogenase activity
XCCCN12_RS11345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCCCN12_RS11355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCCCN12_RS11360	COG2223	nitrite transmembrane transporter activity
XCCCN12_RS11365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCCCN12_RS11375	COG0243	molybdopterin cofactor binding
XCCCN12_RS11395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCCCN12_RS11405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN12_RS11415	COG0579	oxidoreductase
XCCCN12_RS11440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCCCN12_RS11480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN12_RS11585	COG3685	Protein conserved in bacteria
XCCCN12_RS11590	COG2201	protein-glutamate methylesterase activity
XCCCN12_RS11600	COG5001	Diguanylate cyclase
XCCCN12_RS11680	COG3590	peptidase
XCCCN12_RS11695	COG1999	signal sequence binding
XCCCN12_RS11710	COG1733	regulation of RNA biosynthetic process
XCCCN12_RS11740	COG1238	metal cluster binding
XCCCN12_RS11750	COG0840	transmembrane signaling receptor activity
XCCCN12_RS11785	COG0840	transmembrane signaling receptor activity
XCCCN12_RS11790	COG0784	Response regulator, receiver
XCCCN12_RS11790	COG4191	Histidine kinase
XCCCN12_RS11805	COG3279	Response regulator of the LytR AlgR family
XCCCN12_RS12005	COG1196	nuclear chromosome segregation
XCCCN12_RS12270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCCCN12_RS12305	COG0428	transporter
XCCCN12_RS12315	COG1530	ribonuclease E activity
XCCCN12_RS12350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCCCN12_RS12380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN12_RS12395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCCCN12_RS12415	COG0848	biopolymer transport protein
XCCCN12_RS12420	COG0811	peptide transport
XCCCN12_RS12445	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCCCN12_RS12460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCCCN12_RS12475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCCCN12_RS12490	COG0354	folic acid binding
XCCCN12_RS12500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCCCN12_RS12510	COG0363	glucosamine-6-phosphate deaminase activity
XCCCN12_RS12515	COG0129	dihydroxy-acid dehydratase activity
XCCCN12_RS12520	COG0800	Aldolase
XCCCN12_RS12600	COG5001	Diguanylate cyclase
XCCCN12_RS12605	COG2183	response to ionizing radiation
XCCCN12_RS12615	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN12_RS12615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN12_RS12630	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCCCN12_RS12640	COG1183	phosphatidylcholine synthase activity
XCCCN12_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS12675	COG0668	transmembrane transport
XCCCN12_RS12695	COG1914	H( )-stimulated, divalent metal cation uptake system
XCCCN12_RS12710	COG2814	Major facilitator Superfamily
XCCCN12_RS12725	COG1335	isochorismatase
XCCCN12_RS12740	COG2197	response regulator
XCCCN12_RS12765	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN12_RS12790	COG0475	glutathione-regulated potassium exporter activity
XCCCN12_RS12790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN12_RS12795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCCCN12_RS12810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCCCN12_RS12825	COG0539	negative regulation of cytoplasmic translation
XCCCN12_RS12845	COG2957	Belongs to the agmatine deiminase family
XCCCN12_RS12850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN12_RS12875	COG0395	ABC-type sugar transport system, permease component
XCCCN12_RS12910	COG2350	Protein conserved in bacteria
XCCCN12_RS12915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCCCN12_RS12920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCCCN12_RS12925	COG1187	pseudouridine synthase activity
XCCCN12_RS12945	COG0436	Aminotransferase
XCCCN12_RS13010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCCCN12_RS13015	COG4988	ABC transporter
XCCCN12_RS13025	COG1294	oxidase, subunit
XCCCN12_RS13060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XCCCN12_RS13090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCCCN12_RS13095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN12_RS13100	COG0137	argininosuccinate synthase activity
XCCCN12_RS13110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCCCN12_RS13125	COG2166	iron-sulfur cluster assembly
XCCCN12_RS13160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCCCN12_RS13180	COG4302	ethanolamine ammonia-lyase activity
XCCCN12_RS13205	COG4677	pectinesterase activity
XCCCN12_RS13230	COG0402	S-adenosylhomocysteine deaminase activity
XCCCN12_RS13245	COG1509	lysine 2,3-aminomutase activity
XCCCN12_RS13250	COG3300	MHYT domain
XCCCN12_RS13250	COG5001	Diguanylate cyclase
XCCCN12_RS13265	COG0483	inositol monophosphate 1-phosphatase activity
XCCCN12_RS13270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN12_RS13285	COG0488	(ABC) transporter
XCCCN12_RS13290	COG0513	Belongs to the DEAD box helicase family
XCCCN12_RS13325	COG4681	YaeQ
XCCCN12_RS13330	COG2081	HI0933 family
XCCCN12_RS13335	COG5001	Diguanylate cyclase
XCCCN12_RS13335	COG3300	MHYT domain
XCCCN12_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS13375	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCCCN12_RS13385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCCCN12_RS13385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCCCN12_RS13390	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCCCN12_RS13405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCCCN12_RS13435	COG0582	viral genome integration into host DNA
XCCCN12_RS13485	COG0835	chemotaxis
XCCCN12_RS13490	COG0840	transmembrane signaling receptor activity
XCCCN12_RS13500	COG1201	RNA secondary structure unwinding
XCCCN12_RS13515	COG2969	positive regulation of protein catabolic process
XCCCN12_RS13520	COG0625	glutathione transferase activity
XCCCN12_RS13525	COG2857	Cytochrome c1
XCCCN12_RS13530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCCCN12_RS13535	COG0723	plastoquinol--plastocyanin reductase activity
XCCCN12_RS13540	COG0741	lytic transglycosylase activity
XCCCN12_RS13560	COG1702	phosphate starvation-inducible protein PhoH
XCCCN12_RS13580	COG4535	Mg2 and Co2 transporter CorC
XCCCN12_RS13600	COG1012	belongs to the aldehyde dehydrogenase family
XCCCN12_RS13610	COG1177	transmembrane transport
XCCCN12_RS13615	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCCCN12_RS13625	COG3842	ATPase activity
XCCCN12_RS13660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCCCN12_RS13665	COG0174	glutamine synthetase
XCCCN12_RS13670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN12_RS13680	COG2703	oxygen carrier activity
XCCCN12_RS13685	COG0477	Major facilitator Superfamily
XCCCN12_RS13695	COG0243	molybdopterin cofactor binding
XCCCN12_RS13705	COG2223	nitrite transmembrane transporter activity
XCCCN12_RS13710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCCCN12_RS13720	COG2733	membrane
XCCCN12_RS13725	COG2205	protein histidine kinase activity
XCCCN12_RS13725	COG5002	protein histidine kinase activity
XCCCN12_RS13725	COG0784	Response regulator, receiver
XCCCN12_RS13735	COG0477	Major facilitator Superfamily
XCCCN12_RS13740	COG1335	isochorismatase
XCCCN12_RS13745	COG2207	Transcriptional regulator
XCCCN12_RS13745	COG1609	Transcriptional regulator
XCCCN12_RS13750	COG2902	Dehydrogenase
XCCCN12_RS13760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN12_RS13780	COG1609	Transcriptional regulator
XCCCN12_RS13785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN12_RS13785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN12_RS13790	COG1105	Belongs to the carbohydrate kinase PfkB family
XCCCN12_RS13795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN12_RS13795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCCCN12_RS13815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCCCN12_RS13825	COG1862	Preprotein translocase
XCCCN12_RS13845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCCCN12_RS13875	COG3291	Pkd domain containing protein
XCCCN12_RS13880	COG0405	Gamma-glutamyltransferase
XCCCN12_RS13885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCCCN12_RS13905	COG0742	ribosomal rna small subunit methyltransferase
XCCCN12_RS13910	COG0326	Molecular chaperone. Has ATPase activity
XCCCN12_RS13915	COG2801	Transposase and inactivated derivatives
XCCCN12_RS13990	COG0531	amino acid
XCCCN12_RS14010	COG0006	proline dipeptidase activity
XCCCN12_RS14020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCCCN12_RS14040	COG3938	Belongs to the proline racemase family
XCCCN12_RS14050	COG0552	protein localization to endoplasmic reticulum
XCCCN12_RS14075	COG0784	Response regulator, receiver
XCCCN12_RS14075	COG4191	Histidine kinase
XCCCN12_RS14085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCCCN12_RS14110	COG0322	excinuclease ABC activity
XCCCN12_RS14145	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS14175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCCCN12_RS14180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN12_RS14185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCCCN12_RS14210	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS14215	COG2244	polysaccharide biosynthetic process
XCCCN12_RS14220	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS14225	COG0438	transferase activity, transferring glycosyl groups
XCCCN12_RS14295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCCCN12_RS14325	COG1082	Xylose isomerase domain protein TIM barrel
XCCCN12_RS14340	COG0366	Alpha amylase catalytic
XCCCN12_RS14360	COG3409	Peptidoglycan-binding domain 1 protein
XCCCN12_RS14360	COG3501	Rhs element vgr protein
XCCCN12_RS14390	COG3702	type iv secretory pathway
XCCCN12_RS14410	COG2948	multi-organism process
XCCCN12_RS14430	COG3505	Type IV secretory pathway VirD4
XCCCN12_RS14505	COG3275	phosphorelay sensor kinase activity
XCCCN12_RS14510	COG1611	Belongs to the LOG family
XCCCN12_RS14525	COG2095	MarC family integral membrane protein
XCCCN12_RS14535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN12_RS14595	COG0195	Participates in both transcription termination and antitermination
XCCCN12_RS14610	COG1007	ATP synthesis coupled electron transport
XCCCN12_RS14630	COG0839	Belongs to the complex I subunit 6 family
XCCCN12_RS14650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCCCN12_RS14655	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCCCN12_RS14675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCCCN12_RS14695	COG0300	oxidoreductase activity
XCCCN12_RS14795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCCCN12_RS14800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCCCN12_RS14815	COG2890	protein-(glutamine-N5) methyltransferase activity
XCCCN12_RS14840	COG0433	COG0433 Predicted ATPase
XCCCN12_RS14855	COG0494	nUDIX hydrolase
XCCCN12_RS14900	COG0717	Belongs to the dCTP deaminase family
XCCCN12_RS14905	COG0489	protein tyrosine kinase activity
XCCCN12_RS14925	COG3590	peptidase
XCCCN12_RS14930	COG3590	peptidase
XCCCN12_RS14950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCCCN12_RS14955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCCCN12_RS14960	COG2311	Membrane
XCCCN12_RS14965	COG1047	Peptidyl-prolyl cis-trans
XCCCN12_RS14970	COG0791	NLP P60 protein
XCCCN12_RS14975	COG0791	NLP P60 protein
XCCCN12_RS15010	COG4191	Histidine kinase
XCCCN12_RS15025	COG4106	trans-aconitate 2-methyltransferase activity
XCCCN12_RS15030	COG1301	dicarboxylic acid transport
XCCCN12_RS15035	COG1785	Belongs to the alkaline phosphatase family
XCCCN12_RS15050	COG0142	geranyltranstransferase activity
XCCCN12_RS15065	COG0312	modulator of DNA gyrase
XCCCN12_RS15075	COG0312	modulator of DNA gyrase
XCCCN12_RS15085	COG3164	Protein of unknown function
XCCCN12_RS15100	COG2968	Membrane
XCCCN12_RS15130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCCCN12_RS15155	COG3118	belongs to the thioredoxin family
XCCCN12_RS15165	COG2155	Conserved Protein
XCCCN12_RS15215	COG1132	(ABC) transporter
XCCCN12_RS15220	COG0475	glutathione-regulated potassium exporter activity
XCCCN12_RS15245	COG1187	pseudouridine synthase activity
XCCCN12_RS15250	COG5002	protein histidine kinase activity
XCCCN12_RS15250	COG5001	Diguanylate cyclase
XCCCN12_RS15305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCCCN12_RS15350	COG1294	oxidase, subunit
XCCCN12_RS15355	COG1271	oxidase subunit
XCCCN12_RS15365	COG3383	formate dehydrogenase (NAD+) activity
XCCCN12_RS15375	COG1404	Belongs to the peptidase S8 family
XCCCN12_RS15400	COG2814	Major facilitator Superfamily
XCCCN12_RS15405	COG0583	DNA-binding transcription factor activity
XCCCN12_RS15425	COG2207	Transcriptional regulator
XCCCN12_RS15440	COG0667	Aldo Keto reductase
XCCCN12_RS15445	COG1309	transcriptional regulator
XCCCN12_RS15455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN12_RS15470	COG0735	belongs to the Fur family
XCCCN12_RS15505	COG4452	Inner membrane protein CreD
XCCCN12_RS15510	COG2205	protein histidine kinase activity
XCCCN12_RS15520	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS15525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCCCN12_RS15540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCCCN12_RS15550	COG0643	Histidine kinase
XCCCN12_RS15550	COG2198	Histidine kinase
XCCCN12_RS15555	COG0840	transmembrane signaling receptor activity
XCCCN12_RS15560	COG0835	chemotaxis
XCCCN12_RS15570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCCCN12_RS15580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS15585	COG3590	peptidase
XCCCN12_RS15605	COG1741	Belongs to the pirin family
XCCCN12_RS15625	COG1741	Belongs to the pirin family
XCCCN12_RS15630	COG1966	Carbon starvation protein
XCCCN12_RS15635	COG2879	small protein
XCCCN12_RS15670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCCCN12_RS15675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCCCN12_RS15680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCCCN12_RS15685	COG2080	2 iron, 2 sulfur cluster binding
XCCCN12_RS15690	COG0604	alcohol dehydrogenase
XCCCN12_RS15695	COG3706	GGDEF domain
XCCCN12_RS15695	COG2203	Gaf domain
XCCCN12_RS15695	COG5001	Diguanylate cyclase
XCCCN12_RS15695	COG4251	negative regulation of phosphorylation
XCCCN12_RS15700	COG4251	negative regulation of phosphorylation
XCCCN12_RS15705	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS15715	COG3713	MltA-interacting MipA family protein
XCCCN12_RS15725	COG0629	single-stranded DNA binding
XCCCN12_RS15730	COG0142	geranyltranstransferase activity
XCCCN12_RS15755	COG0527	aspartate kinase activity
XCCCN12_RS15760	COG0384	phenazine biosynthesis protein PhzF
XCCCN12_RS15765	COG0384	phenazine biosynthesis protein PhzF
XCCCN12_RS15775	COG1764	response to oxidative stress
XCCCN12_RS15795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCCCN12_RS15800	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN12_RS15830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCCCN12_RS15865	COG0693	protein deglycase activity
XCCCN12_RS15880	COG0719	Fe-S assembly protein
XCCCN12_RS15885	COG0396	ATPase activity
XCCCN12_RS15890	COG0719	Fe-S assembly protein
XCCCN12_RS15895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCCCN12_RS15910	COG2146	nitrite reductase [NAD(P)H] activity
XCCCN12_RS15915	COG4774	siderophore transport
XCCCN12_RS15960	COG1555	photosystem II stabilization
XCCCN12_RS15965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCCCN12_RS15980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCCCN12_RS15990	COG0628	permease
XCCCN12_RS16010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCCCN12_RS16035	COG0271	Belongs to the BolA IbaG family
XCCCN12_RS16045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCCCN12_RS16060	COG1137	ATPase activity
XCCCN12_RS16075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN12_RS16095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCCCN12_RS16100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCCCN12_RS16105	COG2239	Acts as a magnesium transporter
XCCCN12_RS16115	COG1294	oxidase, subunit
XCCCN12_RS16120	COG1271	oxidase subunit
XCCCN12_RS16125	COG1113	amino acid transport
XCCCN12_RS16150	COG2197	response regulator
XCCCN12_RS16155	COG0531	amino acid
XCCCN12_RS16230	COG2814	Major facilitator Superfamily
XCCCN12_RS16245	COG0754	glutathionylspermidine amidase activity
XCCCN12_RS16270	COG1842	Phage shock protein A
XCCCN12_RS16315	COG0477	Major facilitator Superfamily
XCCCN12_RS16335	COG2353	YceI-like domain
XCCCN12_RS16355	COG1760	l-serine dehydratase
XCCCN12_RS16370	COG0527	aspartate kinase activity
XCCCN12_RS16370	COG0460	homoserine dehydrogenase
XCCCN12_RS16375	COG0626	cystathionine gamma-synthase activity
XCCCN12_RS16380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN12_RS16395	COG1272	protein, Hemolysin III
XCCCN12_RS16400	COG2982	Protein involved in outer membrane biogenesis
XCCCN12_RS16405	COG0517	IMP dehydrogenase activity
XCCCN12_RS16405	COG0516	GMP reductase activity
XCCCN12_RS16410	COG0463	Glycosyl transferase, family 2
XCCCN12_RS16420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCCCN12_RS16435	COG1309	transcriptional regulator
XCCCN12_RS16440	COG2267	carboxylic ester hydrolase activity
XCCCN12_RS16445	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS16495	COG0330	HflC and HflK could
XCCCN12_RS16510	COG3956	TIGRFAM MazG family protein
XCCCN12_RS16515	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCCCN12_RS16520	COG0494	nUDIX hydrolase
XCCCN12_RS16530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCCCN12_RS16535	COG0837	glucose binding
XCCCN12_RS16550	COG3858	chitin binding
XCCCN12_RS16550	COG1388	LysM domain
XCCCN12_RS16565	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN12_RS16575	COG3537	Alpha-1,2-mannosidase
XCCCN12_RS16620	COG3645	SOS response
XCCCN12_RS16635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCCCN12_RS16675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XCCCN12_RS16690	COG1446	asparaginase
XCCCN12_RS16695	COG2304	oxidoreductase activity
XCCCN12_RS16700	COG1595	DNA-templated transcription, initiation
XCCCN12_RS16725	COG2198	Histidine kinase
XCCCN12_RS16725	COG0784	Response regulator, receiver
XCCCN12_RS16725	COG0643	Histidine kinase
XCCCN12_RS16730	COG0840	transmembrane signaling receptor activity
XCCCN12_RS16735	COG0835	chemotaxis
XCCCN12_RS16750	COG0189	ligase activity
XCCCN12_RS16775	COG1199	ATP-dependent helicase activity
XCCCN12_RS16785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCCCN12_RS16790	COG1215	transferase activity, transferring glycosyl groups
XCCCN12_RS16800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN12_RS16850	COG1643	Atp-dependent helicase
XCCCN12_RS16855	COG0783	Belongs to the Dps family
XCCCN12_RS16860	COG0514	ATP-dependent DNA helicase (RecQ)
XCCCN12_RS16880	COG1187	pseudouridine synthase activity
XCCCN12_RS16905	COG0583	DNA-binding transcription factor activity
XCCCN12_RS16955	COG0602	queuosine metabolic process
XCCCN12_RS16965	COG2885	chlorophyll binding
XCCCN12_RS16980	COG0848	biopolymer transport protein
XCCCN12_RS16990	COG0824	Thioesterase
XCCCN12_RS17060	COG0477	Major facilitator Superfamily
XCCCN12_RS17080	COG0657	acetylesterase activity
XCCCN12_RS17080	COG2755	lipolytic protein G-D-S-L family
XCCCN12_RS17105	COG0488	(ABC) transporter
XCCCN12_RS17145	COG4651	solute:proton antiporter activity
XCCCN12_RS17145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCCCN12_RS17155	COG4772	TonB-dependent receptor
XCCCN12_RS17165	COG4264	IucA IucC family
XCCCN12_RS17170	COG2814	Major facilitator Superfamily
XCCCN12_RS17175	COG4264	IucA IucC family
XCCCN12_RS17180	COG0019	diaminopimelate decarboxylase activity
XCCCN12_RS17195	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCCCN12_RS17225	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN12_RS17230	COG1797	cobyrinic acid a,c-diamide synthase activity
XCCCN12_RS17250	COG4206	TonB-dependent receptor
XCCCN12_RS17265	COG0542	response to heat
XCCCN12_RS17270	COG1116	anion transmembrane transporter activity
XCCCN12_RS17315	COG1877	trehalose-phosphatase activity
XCCCN12_RS17320	COG3387	PFAM Glycoside hydrolase 15-related
XCCCN12_RS17340	COG0840	transmembrane signaling receptor activity
XCCCN12_RS17360	COG0564	pseudouridine synthase activity
XCCCN12_RS17365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN12_RS17375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCCCN12_RS17375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCCCN12_RS17425	COG1459	type II secretion system
XCCCN12_RS17430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCCCN12_RS17470	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS17530	COG0210	DNA helicase
XCCCN12_RS17555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCCCN12_RS17585	COG2003	Belongs to the UPF0758 family
XCCCN12_RS17620	COG0840	transmembrane signaling receptor activity
XCCCN12_RS17635	COG4191	Histidine kinase
XCCCN12_RS17635	COG0745	RESPONSE REGULATOR receiver
XCCCN12_RS17635	COG2205	protein histidine kinase activity
XCCCN12_RS17640	COG3781	membrane
XCCCN12_RS17650	COG2814	Major facilitator Superfamily
XCCCN12_RS17660	COG0840	transmembrane signaling receptor activity
XCCCN12_RS17805	COG0471	metal ion transport
XCCCN12_RS17805	COG3273	potassium ion transport
XCCCN12_RS17840	COG1609	Transcriptional regulator
XCCCN12_RS17845	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN12_RS17855	COG3250	beta-galactosidase activity
XCCCN12_RS17860	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN12_RS17865	COG2272	Belongs to the type-B carboxylesterase lipase family
XCCCN12_RS17870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCCCN12_RS17875	COG1115	amino acid carrier protein
XCCCN12_RS17885	COG0308	aminopeptidase N
XCCCN12_RS17890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN12_RS17895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCCCN12_RS17900	COG0529	Catalyzes the synthesis of activated sulfate
XCCCN12_RS17900	COG2895	sulfate adenylyltransferase (ATP) activity
XCCCN12_RS17910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCCCN12_RS17940	COG0784	Response regulator, receiver
XCCCN12_RS17940	COG2205	protein histidine kinase activity
XCCCN12_RS17940	COG2198	Histidine kinase
XCCCN12_RS17975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCCCN12_RS17980	COG3588	fructose-bisphosphate aldolase
XCCCN12_RS17985	COG0469	pyruvate kinase activity
XCCCN12_RS18015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCCCN12_RS18030	COG3047	cAMP biosynthetic process
XCCCN12_RS18045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCCCN12_RS18045	COG3453	Protein conserved in bacteria
XCCCN12_RS18050	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCCCN12_RS18055	COG4149	molybdate abc transporter
XCCCN12_RS18085	COG1376	ErfK ybiS ycfS ynhG family protein
XCCCN12_RS18090	COG0739	heme binding
XCCCN12_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS18100	COG0583	DNA-binding transcription factor activity
XCCCN12_RS18105	COG4773	Receptor
XCCCN12_RS18110	COG0596	Alpha beta hydrolase
XCCCN12_RS18115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCCCN12_RS18120	COG1301	dicarboxylic acid transport
XCCCN12_RS18130	COG2304	oxidoreductase activity
XCCCN12_RS18150	COG0714	Associated with various cellular activities
XCCCN12_RS18180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCCCN12_RS18205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCCCN12_RS18215	COG2721	sulfolactate sulfo-lyase activity
XCCCN12_RS18230	COG2271	Major facilitator Superfamily
XCCCN12_RS18245	COG0583	DNA-binding transcription factor activity
XCCCN12_RS18255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCCCN12_RS18270	COG1561	YicC-like family, N-terminal region
XCCCN12_RS18280	COG0346	lactoylglutathione lyase activity
XCCCN12_RS18290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCCCN12_RS18315	COG0006	proline dipeptidase activity
XCCCN12_RS18340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCCCN12_RS18360	COG2912	Transglutaminase-like superfamily
XCCCN12_RS18365	COG1773	rubredoxin
XCCCN12_RS18405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCCCN12_RS18435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCCCN12_RS18440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCCCN12_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS18460	COG0671	phosphoesterase, PA-phosphatase related
XCCCN12_RS18465	COG3781	membrane
XCCCN12_RS18475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCCCN12_RS18490	COG3039	Transposase
XCCCN12_RS18510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCCCN12_RS18525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCCCN12_RS18560	COG4946	Tricorn protease homolog
XCCCN12_RS18560	COG1506	peptidase
XCCCN12_RS18560	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN12_RS18565	COG0840	transmembrane signaling receptor activity
XCCCN12_RS18570	COG0405	Gamma-glutamyltransferase
XCCCN12_RS18610	COG2226	methyltransferase
XCCCN12_RS18620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCCCN12_RS18630	COG3300	MHYT domain
XCCCN12_RS18630	COG5001	Diguanylate cyclase
XCCCN12_RS18640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCCCN12_RS18645	COG1538	Outer membrane efflux protein
XCCCN12_RS18650	COG1519	Transferase
XCCCN12_RS18655	COG1560	Kdo2-lipid A biosynthetic process
XCCCN12_RS18695	COG4191	Histidine kinase
XCCCN12_RS18705	COG2197	response regulator
XCCCN12_RS18720	COG0642	Histidine kinase
XCCCN12_RS18740	COG2851	Citrate transporter
XCCCN12_RS18745	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS18750	COG1609	Transcriptional regulator
XCCCN12_RS18755	COG2211	Major facilitator Superfamily
XCCCN12_RS18780	COG1162	GTPase activity
XCCCN12_RS18815	COG0436	Aminotransferase
XCCCN12_RS18835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCCCN12_RS18855	COG1228	amidohydrolase
XCCCN12_RS18895	COG1307	EDD domain protein, DegV family
XCCCN12_RS18905	COG0697	spore germination
XCCCN12_RS18915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCCCN12_RS18925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XCCCN12_RS18945	COG0583	DNA-binding transcription factor activity
XCCCN12_RS18970	COG2205	protein histidine kinase activity
XCCCN12_RS18995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCCCN12_RS19005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCCCN12_RS19045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCCCN12_RS19050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCCCN12_RS19055	COG1609	Transcriptional regulator
XCCCN12_RS19065	COG2188	Transcriptional regulator
XCCCN12_RS19090	COG4795	General secretion pathway protein
XCCCN12_RS19095	COG2165	general secretion pathway protein
XCCCN12_RS19110	COG1459	type II secretion system
XCCCN12_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS19160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCCCN12_RS19165	COG4191	Histidine kinase
XCCCN12_RS19170	COG0784	Response regulator, receiver
XCCCN12_RS19175	COG4251	negative regulation of phosphorylation
XCCCN12_RS19180	COG2823	Periplasmic or secreted lipoprotein
XCCCN12_RS19185	COG0673	inositol 2-dehydrogenase activity
XCCCN12_RS19190	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCCCN12_RS19225	COG1051	belongs to the nudix hydrolase family
XCCCN12_RS19225	COG1056	cytidyltransferase-related domain
XCCCN12_RS19270	COG1686	Belongs to the peptidase S11 family
XCCCN12_RS19275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCCCN12_RS19280	COG2951	lytic endotransglycosylase activity
XCCCN12_RS19325	COG0772	Belongs to the SEDS family
XCCCN12_RS19340	COG1792	Involved in formation and maintenance of cell shape
XCCCN12_RS19350	COG1077	Cell shape determining protein MreB Mrl
XCCCN12_RS19355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCCCN12_RS19360	COG3284	Transcriptional regulator
XCCCN12_RS19375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCCCN12_RS19410	COG0308	aminopeptidase N
XCCCN12_RS19415	COG5001	Diguanylate cyclase
XCCCN12_RS19415	COG3300	MHYT domain
XCCCN12_RS19420	COG2226	methyltransferase
XCCCN12_RS19480	COG2832	Protein of unknown function (DUF454)
XCCCN12_RS19500	COG0436	Aminotransferase
XCCCN12_RS19515	COG1505	serine-type exopeptidase activity
XCCCN12_RS19555	COG3275	phosphorelay sensor kinase activity
XCCCN12_RS19575	COG3273	potassium ion transport
XCCCN12_RS19575	COG0471	metal ion transport
XCCCN12_RS19590	COG3706	GGDEF domain
XCCCN12_RS19595	COG0659	secondary active sulfate transmembrane transporter activity
XCCCN12_RS19600	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN12_RS19600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCCCN12_RS19610	COG0840	transmembrane signaling receptor activity
XCCCN12_RS19615	COG5002	protein histidine kinase activity
XCCCN12_RS19615	COG3447	MASE1 domain protein
XCCCN12_RS19615	COG5001	Diguanylate cyclase
XCCCN12_RS19675	COG1113	amino acid transport
XCCCN12_RS19685	COG5297	Belongs to the glycosyl hydrolase family 6
XCCCN12_RS19690	COG4305	rare lipoprotein A
XCCCN12_RS19705	COG0697	spore germination
XCCCN12_RS19745	COG1959	2 iron, 2 sulfur cluster binding
XCCCN12_RS19760	COG1506	peptidase
XCCCN12_RS19760	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN12_RS19765	COG2409	Drug exporters of the RND superfamily
XCCCN12_RS19825	COG0435	Glutathione S-transferase
XCCCN12_RS19875	COG0367	asparagine synthase
XCCCN12_RS19880	COG1506	peptidase
XCCCN12_RS19880	COG0823	Involved in the tonB-independent uptake of proteins
XCCCN12_RS19895	COG1595	DNA-templated transcription, initiation
XCCCN12_RS20025	COG1802	Transcriptional regulator
XCCCN12_RS20080	COG2353	YceI-like domain
XCCCN12_RS20105	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCCCN12_RS20145	COG3712	iron ion homeostasis
XCCCN12_RS20165	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN12_RS20195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCCCN12_RS20205	COG3550	peptidyl-serine autophosphorylation
XCCCN12_RS20235	COG1196	nuclear chromosome segregation
XCCCN12_RS20245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XCCCN12_RS20260	COG2356	endonuclease I
XCCCN12_RS20265	COG1324	tolerance protein
XCCCN12_RS20280	COG0511	ligase activity, forming carbon-carbon bonds
XCCCN12_RS20290	COG0439	Biotin carboxylase
XCCCN12_RS20325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCCCN12_RS20340	COG4589	Belongs to the CDS family
XCCCN12_RS20365	COG0671	phosphoesterase, PA-phosphatase related
XCCCN12_RS20365	COG2453	phosphatase
XCCCN12_RS20370	COG2267	carboxylic ester hydrolase activity
XCCCN12_RS20375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCCCN12_RS20390	COG0151	Belongs to the GarS family
XCCCN12_RS20395	COG1289	transmembrane transporter activity
XCCCN12_RS20405	COG2814	Major facilitator Superfamily
XCCCN12_RS20435	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCCCN12_RS20440	COG2816	NAD+ diphosphatase activity
XCCCN12_RS20555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCCCN12_RS20570	COG0436	Aminotransferase
XCCCN12_RS20650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCCCN12_RS20650	COG2111	Na H antiporter
XCCCN12_RS20655	COG1006	Multisubunit Na H antiporter MnhC subunit
XCCCN12_RS20660	COG0651	ATP synthesis coupled electron transport
XCCCN12_RS20670	COG2212	antiporter activity
XCCCN12_RS20675	COG1320	monovalent cation:proton antiporter activity
XCCCN12_RS20705	COG2852	Protein conserved in bacteria
XCCCN12_RS20725	COG3104	oligopeptide transport
XCCCN12_RS20740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCCCN12_RS20755	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCCCN12_RS20765	COG0513	Belongs to the DEAD box helicase family
XCCCN12_RS20780	COG2085	NADP oxidoreductase coenzyme F420-dependent
XCCCN12_RS20785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCCCN12_RS20835	COG0702	epimerase
XCCCN12_RS20860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCCCN12_RS20880	COG1649	PFAM Uncharacterised BCR, COG1649
XCCCN12_RS20890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCCCN12_RS20905	COG3264	Mechanosensitive ion channel
XCCCN12_RS20905	COG1511	domain protein
XCCCN12_RS20925	COG4206	TonB-dependent receptor
XCCCN12_RS20950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCCCN12_RS20960	COG4774	siderophore transport
XCCCN12_RS20970	COG0582	viral genome integration into host DNA
XCCCN12_RS20985	COG1040	competence protein
XCCCN12_RS21035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCCCN12_RS21060	COG0657	acetylesterase activity
XCCCN12_RS21070	COG1414	Transcriptional regulator
XCCCN12_RS21080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCCCN12_RS21085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCCCN12_RS21090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XCCCN12_RS21095	COG3485	protocatechuate 3,4-dioxygenase
XCCCN12_RS21100	COG3485	protocatechuate 3,4-dioxygenase
XCCCN12_RS21110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCCCN12_RS21115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCCCN12_RS21140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCCCN12_RS21200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCCCN12_RS21310	COG3039	Transposase
XCCCN12_RS21355	COG3039	Transposase
XCCCN12_RS21395	COG0840	transmembrane signaling receptor activity
XCCCN12_RS21405	COG1733	regulation of RNA biosynthetic process
XCCCN12_RS21410	COG0702	epimerase
XCCCN12_RS21420	COG3321	synthase
XCCCN12_RS21420	COG0604	alcohol dehydrogenase
XCCCN12_RS21425	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS21450	COG0583	DNA-binding transcription factor activity
XCCCN12_RS21455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCCCN12_RS21480	COG1902	pentaerythritol trinitrate reductase activity
XCCCN12_RS21500	COG2814	Major facilitator Superfamily
XCCCN12_RS21505	COG0583	DNA-binding transcription factor activity
XCCCN12_RS21515	COG0084	hydrolase, TatD family'
XCCCN12_RS21535	COG2252	PERMEase
XCCCN12_RS21545	COG1957	nucleoside hydrolase
XCCCN12_RS21560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS21595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCCCN12_RS21615	COG2072	flavoprotein involved in K transport
XCCCN12_RS21620	COG2351	hydroxyisourate hydrolase activity
XCCCN12_RS21625	COG4807	Protein conserved in bacteria
XCCCN12_RS21630	COG0840	transmembrane signaling receptor activity
XCCCN12_RS21635	COG1643	Atp-dependent helicase
XCCCN12_RS21645	COG1187	pseudouridine synthase activity
XCCCN12_RS21660	COG2130	NADP-dependent
XCCCN12_RS21665	COG0656	L-ascorbic acid biosynthetic process
XCCCN12_RS21695	COG1764	response to oxidative stress
XCCCN12_RS21700	COG1846	Transcriptional regulator
XCCCN12_RS21710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCCCN12_RS21720	COG0697	spore germination
XCCCN12_RS21730	COG0523	cobalamin synthesis protein
XCCCN12_RS21785	COG1960	acyl-CoA dehydrogenase activity
XCCCN12_RS21790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCCCN12_RS21795	COG4770	biotin carboxylase activity
XCCCN12_RS21830	COG3039	Transposase
XCCCN12_RS21835	COG2224	Isocitrate lyase
XCCCN12_RS21840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCCCN12_RS21845	COG0583	DNA-binding transcription factor activity
XCCCN12_RS21875	COG0339	signal peptide processing
XCCCN12_RS21880	COG1446	asparaginase
XCCCN12_RS21900	COG0564	pseudouridine synthase activity
XCCCN12_RS21915	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCCCN12_RS21940	COG2091	lysine biosynthetic process via aminoadipic acid
XCCCN12_RS22000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCCCN12_RS22010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCCCN12_RS22015	COG3162	membrane
XCCCN12_RS22050	COG3507	Belongs to the glycosyl hydrolase 43 family
XCCCN12_RS22065	COG1028	Short-chain dehydrogenase reductase Sdr
XCCCN12_RS22070	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCCCN12_RS22075	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN12_RS22085	COG3254	rhamnose metabolic process
XCCCN12_RS22090	COG0738	Major facilitator superfamily
XCCCN12_RS22095	COG1414	Transcriptional regulator
XCCCN12_RS22115	COG2205	protein histidine kinase activity
XCCCN12_RS22115	COG0784	Response regulator, receiver
XCCCN12_RS22125	COG3459	Glycosyltransferase 36 associated
XCCCN12_RS22130	COG2211	Major facilitator Superfamily
XCCCN12_RS22135	COG3265	gluconokinase activity
XCCCN12_RS22140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCCCN12_RS22165	COG2911	Protein conserved in bacteria
XCCCN12_RS22170	COG0729	surface antigen
XCCCN12_RS22185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCCCN12_RS22195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCCCN12_RS22195	COG0519	Catalyzes the synthesis of GMP from XMP
XCCCN12_RS22210	COG0805	protein transport
XCCCN12_RS22230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCCCN12_RS22280	COG3661	Belongs to the glycosyl hydrolase 67 family
XCCCN12_RS22290	COG4948	Mandelate Racemase Muconate Lactonizing
XCCCN12_RS22300	COG1472	Belongs to the glycosyl hydrolase 3 family
XCCCN12_RS22305	COG0246	Mannitol dehydrogenase
XCCCN12_RS22335	COG3386	PFAM SMP-30 Gluconolaconase
XCCCN12_RS22355	COG3250	beta-galactosidase activity
XCCCN12_RS22365	COG3693	PFAM glycoside hydrolase, family 10
XCCCN12_RS22380	COG2211	Major facilitator Superfamily
XCCCN12_RS22420	COG2937	Belongs to the GPAT DAPAT family
XCCCN12_RS22455	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCCCN12_RS22475	COG0210	DNA helicase
XCCCN12_RS22505	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCCCN12_RS22550	COG3135	benzoate transporter
XCCCN12_RS22575	COG0676	glucose-6-phosphate 1-epimerase activity
XCCCN12_RS22600	COG0730	response to heat
XCCCN12_RS22625	COG0302	gtp cyclohydrolase
XCCCN12_RS22640	COG1566	PFAM secretion protein HlyD family protein
XCCCN12_RS22650	COG1289	transmembrane transporter activity
XCCCN12_RS22655	COG0477	Major facilitator Superfamily
XCCCN12_RS22665	COG0583	DNA-binding transcription factor activity
XCCCN12_RS22670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCCCN12_RS22750	COG0564	pseudouridine synthase activity
XCCCN12_RS22800	COG1074	ATP-dependent DNA helicase activity
XCCCN12_RS22805	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCCCN12_RS22840	COG1127	ABC transporter
XCCCN12_RS22845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCCCN12_RS22850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCCCN12_RS22865	COG2853	Lipoprotein
XCCCN12_RS22875	COG0386	Belongs to the glutathione peroxidase family
XCCCN12_RS22885	COG1322	Protein conserved in bacteria
XCCCN12_RS22895	COG0604	alcohol dehydrogenase
XCCCN12_RS22900	COG0583	DNA-binding transcription factor activity
XCCCN12_RS22915	COG0531	amino acid
XCCCN12_RS22925	COG4206	TonB-dependent receptor
XCCCN12_RS22935	COG3706	GGDEF domain
XCCCN12_RS22940	COG3835	regulator
XCCCN12_RS22945	COG1929	Belongs to the glycerate kinase type-1 family
XCCCN12_RS22950	COG2271	Major facilitator Superfamily
XCCCN12_RS22975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCCCN12_RS22985	COG0861	Integral membrane protein TerC family
XCCCN12_RS23015	COG0584	glycerophosphoryl diester phosphodiesterase
XCCCN12_RS23030	COG0671	phosphoesterase, PA-phosphatase related
XCCCN12_RS23045	COG0726	polysaccharide deacetylase
XCCCN12_RS23050	COG0706	membrane insertase activity