locus-tag	class	description
BIU85_RS00025	COG0187	DNA topoisomerase II activity
BIU85_RS00035	COG0501	Belongs to the peptidase M48B family
BIU85_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS00085	COG4974	Belongs to the 'phage' integrase family
BIU85_RS00100	COG1104	cysteine desulfurase activity
BIU85_RS00120	COG0326	Molecular chaperone. Has ATPase activity
BIU85_RS00205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BIU85_RS00210	COG0793	Belongs to the peptidase S41A family
BIU85_RS00215	COG4942	peptidase
BIU85_RS00225	COG2234	aminopeptidase activity
BIU85_RS00240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BIU85_RS00245	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BIU85_RS00250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BIU85_RS00255	COG1064	alcohol dehydrogenase
BIU85_RS00265	COG0493	'glutamate synthase
BIU85_RS00270	COG0070	glutamate synthase
BIU85_RS00270	COG0069	glutamate synthase activity
BIU85_RS00270	COG0067	glutamate synthase
BIU85_RS00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BIU85_RS00295	COG1741	Belongs to the pirin family
BIU85_RS00300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BIU85_RS00320	COG0583	DNA-binding transcription factor activity
BIU85_RS00380	COG1205	dead DEAH box helicase
BIU85_RS00380	COG1111	helicase
BIU85_RS00385	COG3177	Filamentation induced by cAMP protein fic
BIU85_RS00390	COG1272	protein, Hemolysin III
BIU85_RS00475	COG3237	CsbD-like
BIU85_RS00525	COG0628	permease
BIU85_RS00530	COG0657	acetylesterase activity
BIU85_RS00540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BIU85_RS00545	COG0477	Major facilitator Superfamily
BIU85_RS00585	COG0714	Associated with various cellular activities
BIU85_RS00630	COG4772	TonB-dependent receptor
BIU85_RS00645	COG1012	belongs to the aldehyde dehydrogenase family
BIU85_RS00675	COG1755	Isoprenylcysteine carboxyl methyltransferase
BIU85_RS00680	COG4585	Histidine kinase
BIU85_RS00685	COG2197	response regulator
BIU85_RS00715	COG3710	Transcriptional regulator
BIU85_RS00735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIU85_RS00765	COG4916	TIR domain
BIU85_RS00795	COG3039	Transposase
BIU85_RS00805	COG0366	Alpha amylase catalytic
BIU85_RS00810	COG0366	Alpha amylase catalytic
BIU85_RS00855	COG2755	lipolytic protein G-D-S-L family
BIU85_RS00865	COG0657	acetylesterase activity
BIU85_RS00865	COG2755	lipolytic protein G-D-S-L family
BIU85_RS00875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BIU85_RS00890	COG3507	Belongs to the glycosyl hydrolase 43 family
BIU85_RS00895	COG1609	Transcriptional regulator
BIU85_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS00915	COG2755	lipolytic protein G-D-S-L family
BIU85_RS00925	COG3186	Phenylalanine-4-hydroxylase
BIU85_RS00930	COG1522	sequence-specific DNA binding
BIU85_RS00945	COG1752	Esterase of the alpha-beta hydrolase superfamily
BIU85_RS00955	COG1119	ATPase activity
BIU85_RS00970	COG0517	IMP dehydrogenase activity
BIU85_RS00970	COG1125	glycine betaine transport
BIU85_RS00985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BIU85_RS00990	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BIU85_RS01020	COG0489	protein tyrosine kinase activity
BIU85_RS01025	COG0588	phosphoglycerate mutase activity
BIU85_RS01035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS01060	COG1881	PFAM PEBP family protein
BIU85_RS01080	COG0174	glutamine synthetase
BIU85_RS01085	COG0347	Belongs to the P(II) protein family
BIU85_RS01090	COG0004	ammonium transporteR
BIU85_RS01095	COG3852	Histidine kinase
BIU85_RS01100	COG2204	response regulator
BIU85_RS01110	COG2032	superoxide dismutase activity
BIU85_RS01115	COG2032	superoxide dismutase activity
BIU85_RS01120	COG0346	lactoylglutathione lyase activity
BIU85_RS01130	COG0183	Belongs to the thiolase family
BIU85_RS01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BIU85_RS01190	COG0028	Belongs to the TPP enzyme family
BIU85_RS01205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BIU85_RS01220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIU85_RS01225	COG3177	Filamentation induced by cAMP protein fic
BIU85_RS01230	COG0596	Alpha beta hydrolase
BIU85_RS01235	COG0727	PFAM Uncharacterised protein family (UPF0153)
BIU85_RS01245	COG0318	PFAM AMP-dependent synthetase and ligase
BIU85_RS01250	COG0745	RESPONSE REGULATOR receiver
BIU85_RS01265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BIU85_RS01290	COG1181	Belongs to the D-alanine--D-alanine ligase family
BIU85_RS01305	COG0564	pseudouridine synthase activity
BIU85_RS01325	COG1446	asparaginase
BIU85_RS01330	COG0339	signal peptide processing
BIU85_RS01365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BIU85_RS01370	COG2224	Isocitrate lyase
BIU85_RS01375	COG3039	Transposase
BIU85_RS01410	COG4770	biotin carboxylase activity
BIU85_RS01415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BIU85_RS01420	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS01475	COG0523	cobalamin synthesis protein
BIU85_RS01485	COG0697	spore germination
BIU85_RS01495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BIU85_RS01505	COG1846	Transcriptional regulator
BIU85_RS01510	COG1764	response to oxidative stress
BIU85_RS01540	COG0656	L-ascorbic acid biosynthetic process
BIU85_RS01545	COG2130	NADP-dependent
BIU85_RS01560	COG1187	pseudouridine synthase activity
BIU85_RS01570	COG1643	Atp-dependent helicase
BIU85_RS01575	COG0840	transmembrane signaling receptor activity
BIU85_RS01580	COG4807	Protein conserved in bacteria
BIU85_RS01585	COG2351	hydroxyisourate hydrolase activity
BIU85_RS01590	COG2072	flavoprotein involved in K transport
BIU85_RS01610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BIU85_RS01645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS01660	COG1957	nucleoside hydrolase
BIU85_RS01670	COG2252	PERMEase
BIU85_RS01690	COG0084	hydrolase, TatD family'
BIU85_RS01700	COG0583	DNA-binding transcription factor activity
BIU85_RS01705	COG2814	Major facilitator Superfamily
BIU85_RS01725	COG1902	pentaerythritol trinitrate reductase activity
BIU85_RS01750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BIU85_RS01755	COG0583	DNA-binding transcription factor activity
BIU85_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS01785	COG3321	synthase
BIU85_RS01785	COG0604	alcohol dehydrogenase
BIU85_RS01795	COG0702	epimerase
BIU85_RS01800	COG1733	regulation of RNA biosynthetic process
BIU85_RS01810	COG0840	transmembrane signaling receptor activity
BIU85_RS01850	COG3039	Transposase
BIU85_RS01905	COG3039	Transposase
BIU85_RS02005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BIU85_RS02070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BIU85_RS02095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BIU85_RS02100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BIU85_RS02110	COG3485	protocatechuate 3,4-dioxygenase
BIU85_RS02115	COG3485	protocatechuate 3,4-dioxygenase
BIU85_RS02120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BIU85_RS02125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIU85_RS02130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BIU85_RS02140	COG1414	Transcriptional regulator
BIU85_RS02150	COG0657	acetylesterase activity
BIU85_RS02175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BIU85_RS02225	COG1040	competence protein
BIU85_RS02240	COG0582	viral genome integration into host DNA
BIU85_RS02250	COG4774	siderophore transport
BIU85_RS02260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BIU85_RS02285	COG4206	TonB-dependent receptor
BIU85_RS02305	COG3264	Mechanosensitive ion channel
BIU85_RS02305	COG1511	domain protein
BIU85_RS02320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BIU85_RS02330	COG1649	PFAM Uncharacterised BCR, COG1649
BIU85_RS02350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BIU85_RS02375	COG0702	epimerase
BIU85_RS02425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIU85_RS02430	COG2085	NADP oxidoreductase coenzyme F420-dependent
BIU85_RS02445	COG0513	Belongs to the DEAD box helicase family
BIU85_RS02455	COG0508	dehydrogenase complex catalyzes the overall conversion of
BIU85_RS02470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BIU85_RS02490	COG3104	oligopeptide transport
BIU85_RS02510	COG2852	Protein conserved in bacteria
BIU85_RS02540	COG1320	monovalent cation:proton antiporter activity
BIU85_RS02545	COG2212	antiporter activity
BIU85_RS02555	COG0651	ATP synthesis coupled electron transport
BIU85_RS02560	COG1006	Multisubunit Na H antiporter MnhC subunit
BIU85_RS02565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BIU85_RS02565	COG2111	Na H antiporter
BIU85_RS02645	COG0436	Aminotransferase
BIU85_RS02660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BIU85_RS02770	COG2816	NAD+ diphosphatase activity
BIU85_RS02775	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BIU85_RS02805	COG2814	Major facilitator Superfamily
BIU85_RS02815	COG1289	transmembrane transporter activity
BIU85_RS02820	COG0151	Belongs to the GarS family
BIU85_RS02835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BIU85_RS02840	COG2267	carboxylic ester hydrolase activity
BIU85_RS02845	COG0671	phosphoesterase, PA-phosphatase related
BIU85_RS02845	COG2453	phosphatase
BIU85_RS02870	COG4589	Belongs to the CDS family
BIU85_RS02885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BIU85_RS02920	COG0439	Biotin carboxylase
BIU85_RS02930	COG0511	ligase activity, forming carbon-carbon bonds
BIU85_RS02945	COG1324	tolerance protein
BIU85_RS02950	COG2356	endonuclease I
BIU85_RS02965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BIU85_RS02975	COG1196	nuclear chromosome segregation
BIU85_RS03005	COG3550	peptidyl-serine autophosphorylation
BIU85_RS03015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BIU85_RS03040	COG3386	PFAM SMP-30 Gluconolaconase
BIU85_RS03060	COG3712	iron ion homeostasis
BIU85_RS03100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BIU85_RS03125	COG2353	YceI-like domain
BIU85_RS03180	COG1802	Transcriptional regulator
BIU85_RS03305	COG1595	DNA-templated transcription, initiation
BIU85_RS03320	COG0823	Involved in the tonB-independent uptake of proteins
BIU85_RS03320	COG1506	peptidase
BIU85_RS03325	COG0367	asparagine synthase
BIU85_RS03375	COG0435	Glutathione S-transferase
BIU85_RS03435	COG2409	Drug exporters of the RND superfamily
BIU85_RS03440	COG1506	peptidase
BIU85_RS03440	COG0823	Involved in the tonB-independent uptake of proteins
BIU85_RS03455	COG1959	2 iron, 2 sulfur cluster binding
BIU85_RS03495	COG0697	spore germination
BIU85_RS03510	COG4305	rare lipoprotein A
BIU85_RS03515	COG5297	Belongs to the glycosyl hydrolase family 6
BIU85_RS03525	COG1113	amino acid transport
BIU85_RS03585	COG5002	protein histidine kinase activity
BIU85_RS03585	COG5001	Diguanylate cyclase
BIU85_RS03585	COG3447	MASE1 domain protein
BIU85_RS03590	COG0840	transmembrane signaling receptor activity
BIU85_RS03600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BIU85_RS03600	COG5297	Belongs to the glycosyl hydrolase family 6
BIU85_RS03605	COG0659	secondary active sulfate transmembrane transporter activity
BIU85_RS03610	COG3706	GGDEF domain
BIU85_RS03625	COG0471	metal ion transport
BIU85_RS03625	COG3273	potassium ion transport
BIU85_RS03645	COG3275	phosphorelay sensor kinase activity
BIU85_RS03685	COG1505	serine-type exopeptidase activity
BIU85_RS03700	COG0436	Aminotransferase
BIU85_RS03720	COG2832	Protein of unknown function (DUF454)
BIU85_RS03780	COG2226	methyltransferase
BIU85_RS03785	COG3300	MHYT domain
BIU85_RS03785	COG5001	Diguanylate cyclase
BIU85_RS03790	COG0308	aminopeptidase N
BIU85_RS03825	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BIU85_RS03840	COG3284	Transcriptional regulator
BIU85_RS03845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIU85_RS03850	COG1077	Cell shape determining protein MreB Mrl
BIU85_RS03860	COG1792	Involved in formation and maintenance of cell shape
BIU85_RS03875	COG0772	Belongs to the SEDS family
BIU85_RS03910	COG2951	lytic endotransglycosylase activity
BIU85_RS03915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BIU85_RS03920	COG1686	Belongs to the peptidase S11 family
BIU85_RS03965	COG1051	belongs to the nudix hydrolase family
BIU85_RS03965	COG1056	cytidyltransferase-related domain
BIU85_RS04000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BIU85_RS04005	COG0673	inositol 2-dehydrogenase activity
BIU85_RS04010	COG2823	Periplasmic or secreted lipoprotein
BIU85_RS04015	COG4251	negative regulation of phosphorylation
BIU85_RS04020	COG0784	Response regulator, receiver
BIU85_RS04025	COG4191	Histidine kinase
BIU85_RS04030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BIU85_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS04080	COG1459	type II secretion system
BIU85_RS04095	COG2165	general secretion pathway protein
BIU85_RS04100	COG4795	General secretion pathway protein
BIU85_RS04125	COG2188	Transcriptional regulator
BIU85_RS04135	COG1609	Transcriptional regulator
BIU85_RS04140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BIU85_RS04145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIU85_RS04185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BIU85_RS04195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BIU85_RS04220	COG2205	protein histidine kinase activity
BIU85_RS04245	COG0583	DNA-binding transcription factor activity
BIU85_RS04265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BIU85_RS04275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BIU85_RS04285	COG0697	spore germination
BIU85_RS04295	COG1307	EDD domain protein, DegV family
BIU85_RS04335	COG1228	amidohydrolase
BIU85_RS04355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BIU85_RS04375	COG0436	Aminotransferase
BIU85_RS04410	COG3039	Transposase
BIU85_RS04445	COG1162	GTPase activity
BIU85_RS04470	COG2211	Major facilitator Superfamily
BIU85_RS04475	COG1609	Transcriptional regulator
BIU85_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS04485	COG2851	Citrate transporter
BIU85_RS04505	COG0642	Histidine kinase
BIU85_RS04520	COG2197	response regulator
BIU85_RS04530	COG4191	Histidine kinase
BIU85_RS04570	COG1560	Kdo2-lipid A biosynthetic process
BIU85_RS04575	COG1519	Transferase
BIU85_RS04580	COG1538	Outer membrane efflux protein
BIU85_RS04585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BIU85_RS04595	COG5001	Diguanylate cyclase
BIU85_RS04595	COG3300	MHYT domain
BIU85_RS04605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIU85_RS04615	COG2226	methyltransferase
BIU85_RS04655	COG0405	Gamma-glutamyltransferase
BIU85_RS04660	COG0840	transmembrane signaling receptor activity
BIU85_RS04665	COG1506	peptidase
BIU85_RS04665	COG4946	Tricorn protease homolog
BIU85_RS04665	COG0823	Involved in the tonB-independent uptake of proteins
BIU85_RS04700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BIU85_RS04715	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BIU85_RS04735	COG3039	Transposase
BIU85_RS04750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BIU85_RS04760	COG3781	membrane
BIU85_RS04765	COG0671	phosphoesterase, PA-phosphatase related
BIU85_RS04775	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS04785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BIU85_RS04790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BIU85_RS04820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BIU85_RS04860	COG1773	rubredoxin
BIU85_RS04865	COG2912	Transglutaminase-like superfamily
BIU85_RS04885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BIU85_RS04910	COG0006	proline dipeptidase activity
BIU85_RS04935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BIU85_RS04945	COG0346	lactoylglutathione lyase activity
BIU85_RS04955	COG1561	YicC-like family, N-terminal region
BIU85_RS04970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BIU85_RS04980	COG0583	DNA-binding transcription factor activity
BIU85_RS04995	COG2271	Major facilitator Superfamily
BIU85_RS05010	COG2721	sulfolactate sulfo-lyase activity
BIU85_RS05020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BIU85_RS05045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BIU85_RS05075	COG0714	Associated with various cellular activities
BIU85_RS05095	COG2304	oxidoreductase activity
BIU85_RS05105	COG1301	dicarboxylic acid transport
BIU85_RS05110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BIU85_RS05115	COG0596	Alpha beta hydrolase
BIU85_RS05120	COG4773	Receptor
BIU85_RS05125	COG0583	DNA-binding transcription factor activity
BIU85_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS05135	COG0739	heme binding
BIU85_RS05140	COG1376	ErfK ybiS ycfS ynhG family protein
BIU85_RS05170	COG4149	molybdate abc transporter
BIU85_RS05175	COG0725	ABC transporter, periplasmic molybdate-binding protein
BIU85_RS05180	COG3453	Protein conserved in bacteria
BIU85_RS05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIU85_RS05195	COG3047	cAMP biosynthetic process
BIU85_RS05210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BIU85_RS05240	COG0469	pyruvate kinase activity
BIU85_RS05245	COG3588	fructose-bisphosphate aldolase
BIU85_RS05250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BIU85_RS05285	COG0784	Response regulator, receiver
BIU85_RS05285	COG2205	protein histidine kinase activity
BIU85_RS05285	COG2198	Histidine kinase
BIU85_RS05315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BIU85_RS05325	COG2895	sulfate adenylyltransferase (ATP) activity
BIU85_RS05325	COG0529	Catalyzes the synthesis of activated sulfate
BIU85_RS05330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIU85_RS05335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIU85_RS05340	COG0308	aminopeptidase N
BIU85_RS05350	COG1115	amino acid carrier protein
BIU85_RS05355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIU85_RS05360	COG2272	Belongs to the type-B carboxylesterase lipase family
BIU85_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
BIU85_RS05370	COG3250	beta-galactosidase activity
BIU85_RS05380	COG5297	Belongs to the glycosyl hydrolase family 6
BIU85_RS05385	COG1609	Transcriptional regulator
BIU85_RS05420	COG3273	potassium ion transport
BIU85_RS05420	COG0471	metal ion transport
BIU85_RS05485	COG0745	RESPONSE REGULATOR receiver
BIU85_RS05525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BIU85_RS05530	COG1459	type II secretion system
BIU85_RS05580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BIU85_RS05580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BIU85_RS05590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIU85_RS05595	COG0564	pseudouridine synthase activity
BIU85_RS05620	COG0840	transmembrane signaling receptor activity
BIU85_RS05640	COG3387	PFAM Glycoside hydrolase 15-related
BIU85_RS05645	COG1877	trehalose-phosphatase activity
BIU85_RS05690	COG1116	anion transmembrane transporter activity
BIU85_RS05695	COG0542	response to heat
BIU85_RS05710	COG4206	TonB-dependent receptor
BIU85_RS05730	COG1797	cobyrinic acid a,c-diamide synthase activity
BIU85_RS05735	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BIU85_RS05765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BIU85_RS05780	COG0019	diaminopimelate decarboxylase activity
BIU85_RS05785	COG4264	IucA IucC family
BIU85_RS05790	COG2814	Major facilitator Superfamily
BIU85_RS05795	COG4264	IucA IucC family
BIU85_RS05805	COG4772	TonB-dependent receptor
BIU85_RS05815	COG4651	solute:proton antiporter activity
BIU85_RS05815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BIU85_RS05855	COG0488	(ABC) transporter
BIU85_RS05880	COG0657	acetylesterase activity
BIU85_RS05880	COG2755	lipolytic protein G-D-S-L family
BIU85_RS05900	COG0477	Major facilitator Superfamily
BIU85_RS05970	COG0824	Thioesterase
BIU85_RS05980	COG0848	biopolymer transport protein
BIU85_RS05995	COG2885	chlorophyll binding
BIU85_RS06005	COG0602	queuosine metabolic process
BIU85_RS06055	COG0583	DNA-binding transcription factor activity
BIU85_RS06080	COG1187	pseudouridine synthase activity
BIU85_RS06100	COG0514	ATP-dependent DNA helicase (RecQ)
BIU85_RS06105	COG0783	Belongs to the Dps family
BIU85_RS06110	COG1643	Atp-dependent helicase
BIU85_RS06160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BIU85_RS06170	COG1215	transferase activity, transferring glycosyl groups
BIU85_RS06175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BIU85_RS06185	COG1199	ATP-dependent helicase activity
BIU85_RS06210	COG0189	ligase activity
BIU85_RS06225	COG0835	chemotaxis
BIU85_RS06230	COG0840	transmembrane signaling receptor activity
BIU85_RS06235	COG0784	Response regulator, receiver
BIU85_RS06235	COG0643	Histidine kinase
BIU85_RS06235	COG2198	Histidine kinase
BIU85_RS06260	COG1595	DNA-templated transcription, initiation
BIU85_RS06265	COG2304	oxidoreductase activity
BIU85_RS06270	COG1446	asparaginase
BIU85_RS06285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BIU85_RS06325	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BIU85_RS06340	COG3645	SOS response
BIU85_RS06385	COG3537	Alpha-1,2-mannosidase
BIU85_RS06395	COG1472	Belongs to the glycosyl hydrolase 3 family
BIU85_RS06410	COG3858	chitin binding
BIU85_RS06410	COG1388	LysM domain
BIU85_RS06425	COG0837	glucose binding
BIU85_RS06430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BIU85_RS06440	COG0494	nUDIX hydrolase
BIU85_RS06445	COG1218	3'(2'),5'-bisphosphate nucleotidase
BIU85_RS06450	COG3956	TIGRFAM MazG family protein
BIU85_RS06465	COG0330	HflC and HflK could
BIU85_RS06515	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS06520	COG2267	carboxylic ester hydrolase activity
BIU85_RS06525	COG1309	transcriptional regulator
BIU85_RS06540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BIU85_RS06550	COG0463	Glycosyl transferase, family 2
BIU85_RS06555	COG0517	IMP dehydrogenase activity
BIU85_RS06555	COG0516	GMP reductase activity
BIU85_RS06560	COG2982	Protein involved in outer membrane biogenesis
BIU85_RS06565	COG1272	protein, Hemolysin III
BIU85_RS06580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIU85_RS06585	COG0626	cystathionine gamma-synthase activity
BIU85_RS06590	COG0527	aspartate kinase activity
BIU85_RS06590	COG0460	homoserine dehydrogenase
BIU85_RS06605	COG1760	l-serine dehydratase
BIU85_RS06625	COG2353	YceI-like domain
BIU85_RS06645	COG0477	Major facilitator Superfamily
BIU85_RS06690	COG1842	Phage shock protein A
BIU85_RS06715	COG0754	glutathionylspermidine amidase activity
BIU85_RS06730	COG2814	Major facilitator Superfamily
BIU85_RS06805	COG0531	amino acid
BIU85_RS06810	COG2197	response regulator
BIU85_RS06835	COG1113	amino acid transport
BIU85_RS06840	COG1271	oxidase subunit
BIU85_RS06845	COG1294	oxidase, subunit
BIU85_RS06855	COG2239	Acts as a magnesium transporter
BIU85_RS06860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIU85_RS06865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIU85_RS06885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIU85_RS06900	COG1137	ATPase activity
BIU85_RS06915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BIU85_RS06925	COG0271	Belongs to the BolA IbaG family
BIU85_RS06950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BIU85_RS06970	COG0628	permease
BIU85_RS06980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BIU85_RS06995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BIU85_RS07000	COG1555	photosystem II stabilization
BIU85_RS07045	COG4774	siderophore transport
BIU85_RS07050	COG2146	nitrite reductase [NAD(P)H] activity
BIU85_RS07065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BIU85_RS07070	COG0719	Fe-S assembly protein
BIU85_RS07075	COG0396	ATPase activity
BIU85_RS07080	COG0719	Fe-S assembly protein
BIU85_RS07095	COG0693	protein deglycase activity
BIU85_RS07130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BIU85_RS07160	COG0519	Catalyzes the synthesis of GMP from XMP
BIU85_RS07165	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BIU85_RS07190	COG1764	response to oxidative stress
BIU85_RS07200	COG0384	phenazine biosynthesis protein PhzF
BIU85_RS07205	COG0384	phenazine biosynthesis protein PhzF
BIU85_RS07210	COG0527	aspartate kinase activity
BIU85_RS07235	COG0142	geranyltranstransferase activity
BIU85_RS07240	COG0629	single-stranded DNA binding
BIU85_RS07250	COG3713	MltA-interacting MipA family protein
BIU85_RS07260	COG0745	RESPONSE REGULATOR receiver
BIU85_RS07265	COG4251	negative regulation of phosphorylation
BIU85_RS07270	COG2203	Gaf domain
BIU85_RS07270	COG4251	negative regulation of phosphorylation
BIU85_RS07270	COG5001	Diguanylate cyclase
BIU85_RS07270	COG3706	GGDEF domain
BIU85_RS07275	COG0604	alcohol dehydrogenase
BIU85_RS07280	COG2080	2 iron, 2 sulfur cluster binding
BIU85_RS07285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BIU85_RS07290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BIU85_RS07295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BIU85_RS07330	COG2879	small protein
BIU85_RS07335	COG1966	Carbon starvation protein
BIU85_RS07340	COG1741	Belongs to the pirin family
BIU85_RS07360	COG1741	Belongs to the pirin family
BIU85_RS07380	COG3590	peptidase
BIU85_RS07385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS07395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BIU85_RS07405	COG0835	chemotaxis
BIU85_RS07410	COG0840	transmembrane signaling receptor activity
BIU85_RS07415	COG0643	Histidine kinase
BIU85_RS07415	COG2198	Histidine kinase
BIU85_RS07425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BIU85_RS07440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BIU85_RS07445	COG0745	RESPONSE REGULATOR receiver
BIU85_RS07455	COG2205	protein histidine kinase activity
BIU85_RS07460	COG4452	Inner membrane protein CreD
BIU85_RS07495	COG0735	belongs to the Fur family
BIU85_RS07510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIU85_RS07520	COG1309	transcriptional regulator
BIU85_RS07525	COG0667	Aldo Keto reductase
BIU85_RS07540	COG2207	Transcriptional regulator
BIU85_RS07560	COG0583	DNA-binding transcription factor activity
BIU85_RS07565	COG2814	Major facilitator Superfamily
BIU85_RS07590	COG1404	Belongs to the peptidase S8 family
BIU85_RS07600	COG3383	formate dehydrogenase (NAD+) activity
BIU85_RS07610	COG1271	oxidase subunit
BIU85_RS07615	COG1294	oxidase, subunit
BIU85_RS07715	COG5002	protein histidine kinase activity
BIU85_RS07715	COG5001	Diguanylate cyclase
BIU85_RS07720	COG1187	pseudouridine synthase activity
BIU85_RS07745	COG0475	glutathione-regulated potassium exporter activity
BIU85_RS07750	COG1132	(ABC) transporter
BIU85_RS07800	COG2155	Conserved Protein
BIU85_RS07810	COG3118	belongs to the thioredoxin family
BIU85_RS07835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BIU85_RS07865	COG2968	Membrane
BIU85_RS07880	COG3164	Protein of unknown function
BIU85_RS07890	COG0312	modulator of DNA gyrase
BIU85_RS07900	COG0312	modulator of DNA gyrase
BIU85_RS07915	COG0142	geranyltranstransferase activity
BIU85_RS07930	COG1785	Belongs to the alkaline phosphatase family
BIU85_RS07935	COG1301	dicarboxylic acid transport
BIU85_RS07940	COG4106	trans-aconitate 2-methyltransferase activity
BIU85_RS07955	COG4191	Histidine kinase
BIU85_RS07990	COG0791	NLP P60 protein
BIU85_RS07995	COG0791	NLP P60 protein
BIU85_RS08000	COG1047	Peptidyl-prolyl cis-trans
BIU85_RS08005	COG2311	Membrane
BIU85_RS08010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BIU85_RS08015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BIU85_RS08035	COG3590	peptidase
BIU85_RS08040	COG3590	peptidase
BIU85_RS08060	COG0489	protein tyrosine kinase activity
BIU85_RS08065	COG0717	Belongs to the dCTP deaminase family
BIU85_RS08110	COG0494	nUDIX hydrolase
BIU85_RS08125	COG0433	COG0433 Predicted ATPase
BIU85_RS08150	COG2890	protein-(glutamine-N5) methyltransferase activity
BIU85_RS08165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BIU85_RS08170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BIU85_RS08270	COG0300	oxidoreductase activity
BIU85_RS08290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BIU85_RS08310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BIU85_RS08315	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BIU85_RS08335	COG0839	Belongs to the complex I subunit 6 family
BIU85_RS08355	COG1007	ATP synthesis coupled electron transport
BIU85_RS08370	COG0195	Participates in both transcription termination and antitermination
BIU85_RS08430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BIU85_RS08440	COG2095	MarC family integral membrane protein
BIU85_RS08455	COG1611	Belongs to the LOG family
BIU85_RS08460	COG3275	phosphorelay sensor kinase activity
BIU85_RS08525	COG3505	Type IV secretory pathway VirD4
BIU85_RS08545	COG2948	multi-organism process
BIU85_RS08565	COG3702	type iv secretory pathway
BIU85_RS08595	COG3501	Rhs element vgr protein
BIU85_RS08595	COG3409	Peptidoglycan-binding domain 1 protein
BIU85_RS08625	COG0366	Alpha amylase catalytic
BIU85_RS08640	COG1082	Xylose isomerase domain protein TIM barrel
BIU85_RS08670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BIU85_RS08740	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS08745	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS08750	COG2244	polysaccharide biosynthetic process
BIU85_RS08755	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS08780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIU85_RS08785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIU85_RS08790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BIU85_RS08820	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS08855	COG0322	excinuclease ABC activity
BIU85_RS08880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BIU85_RS08890	COG0784	Response regulator, receiver
BIU85_RS08890	COG4191	Histidine kinase
BIU85_RS08915	COG0552	protein localization to endoplasmic reticulum
BIU85_RS08925	COG3938	Belongs to the proline racemase family
BIU85_RS08945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIU85_RS08955	COG0006	proline dipeptidase activity
BIU85_RS08975	COG0531	amino acid
BIU85_RS09040	COG2801	Transposase and inactivated derivatives
BIU85_RS09045	COG0326	Molecular chaperone. Has ATPase activity
BIU85_RS09050	COG0742	ribosomal rna small subunit methyltransferase
BIU85_RS09070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BIU85_RS09075	COG0405	Gamma-glutamyltransferase
BIU85_RS09080	COG3291	Pkd domain containing protein
BIU85_RS09110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BIU85_RS09130	COG1862	Preprotein translocase
BIU85_RS09140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BIU85_RS09160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BIU85_RS09160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BIU85_RS09165	COG1105	Belongs to the carbohydrate kinase PfkB family
BIU85_RS09170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIU85_RS09170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIU85_RS09175	COG1609	Transcriptional regulator
BIU85_RS09190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIU85_RS09195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIU85_RS09205	COG2902	Dehydrogenase
BIU85_RS09210	COG2207	Transcriptional regulator
BIU85_RS09210	COG1609	Transcriptional regulator
BIU85_RS09215	COG1335	isochorismatase
BIU85_RS09220	COG0477	Major facilitator Superfamily
BIU85_RS09230	COG0784	Response regulator, receiver
BIU85_RS09230	COG5002	protein histidine kinase activity
BIU85_RS09230	COG2205	protein histidine kinase activity
BIU85_RS09235	COG2733	membrane
BIU85_RS09245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BIU85_RS09250	COG2223	nitrite transmembrane transporter activity
BIU85_RS09260	COG0243	molybdopterin cofactor binding
BIU85_RS09270	COG0477	Major facilitator Superfamily
BIU85_RS09275	COG2703	oxygen carrier activity
BIU85_RS09285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BIU85_RS09290	COG0174	glutamine synthetase
BIU85_RS09295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BIU85_RS09330	COG3842	ATPase activity
BIU85_RS09340	COG1176	ABC-type spermidine putrescine transport system, permease component I
BIU85_RS09345	COG1177	transmembrane transport
BIU85_RS09355	COG1012	belongs to the aldehyde dehydrogenase family
BIU85_RS09375	COG4535	Mg2 and Co2 transporter CorC
BIU85_RS09395	COG1702	phosphate starvation-inducible protein PhoH
BIU85_RS09415	COG0741	lytic transglycosylase activity
BIU85_RS09420	COG0723	plastoquinol--plastocyanin reductase activity
BIU85_RS09425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BIU85_RS09430	COG2857	Cytochrome c1
BIU85_RS09435	COG0625	glutathione transferase activity
BIU85_RS09440	COG2969	positive regulation of protein catabolic process
BIU85_RS09455	COG1201	RNA secondary structure unwinding
BIU85_RS09465	COG0840	transmembrane signaling receptor activity
BIU85_RS09470	COG0835	chemotaxis
BIU85_RS09520	COG0582	viral genome integration into host DNA
BIU85_RS09550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BIU85_RS09570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BIU85_RS09570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BIU85_RS09580	COG0860	N-Acetylmuramoyl-L-alanine amidase
BIU85_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS09620	COG3300	MHYT domain
BIU85_RS09620	COG5001	Diguanylate cyclase
BIU85_RS09625	COG2081	HI0933 family
BIU85_RS09630	COG4681	YaeQ
BIU85_RS09665	COG0513	Belongs to the DEAD box helicase family
BIU85_RS09670	COG0488	(ABC) transporter
BIU85_RS09685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BIU85_RS09690	COG0483	inositol monophosphate 1-phosphatase activity
BIU85_RS09705	COG5001	Diguanylate cyclase
BIU85_RS09705	COG3300	MHYT domain
BIU85_RS09710	COG1509	lysine 2,3-aminomutase activity
BIU85_RS09725	COG0402	S-adenosylhomocysteine deaminase activity
BIU85_RS09750	COG4677	pectinesterase activity
BIU85_RS09775	COG4302	ethanolamine ammonia-lyase activity
BIU85_RS09795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BIU85_RS09830	COG2166	iron-sulfur cluster assembly
BIU85_RS09845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIU85_RS09855	COG0137	argininosuccinate synthase activity
BIU85_RS09860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BIU85_RS09865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BIU85_RS09895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BIU85_RS09930	COG1294	oxidase, subunit
BIU85_RS09940	COG4988	ABC transporter
BIU85_RS09945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BIU85_RS10010	COG0436	Aminotransferase
BIU85_RS10030	COG1187	pseudouridine synthase activity
BIU85_RS10035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BIU85_RS10040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BIU85_RS10045	COG2350	Protein conserved in bacteria
BIU85_RS10080	COG0395	ABC-type sugar transport system, permease component
BIU85_RS10105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BIU85_RS10110	COG2957	Belongs to the agmatine deiminase family
BIU85_RS10130	COG0539	negative regulation of cytoplasmic translation
BIU85_RS10145	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BIU85_RS10160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BIU85_RS10165	COG0475	glutathione-regulated potassium exporter activity
BIU85_RS10165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BIU85_RS10190	COG0514	ATP-dependent DNA helicase (RecQ)
BIU85_RS10215	COG2197	response regulator
BIU85_RS10230	COG1335	isochorismatase
BIU85_RS10245	COG2814	Major facilitator Superfamily
BIU85_RS10260	COG1914	H( )-stimulated, divalent metal cation uptake system
BIU85_RS10280	COG0668	transmembrane transport
BIU85_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS10315	COG1183	phosphatidylcholine synthase activity
BIU85_RS10325	COG3243	poly(R)-hydroxyalkanoic acid synthase
BIU85_RS10340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BIU85_RS10340	COG0723	plastoquinol--plastocyanin reductase activity
BIU85_RS10350	COG2183	response to ionizing radiation
BIU85_RS10355	COG5001	Diguanylate cyclase
BIU85_RS10435	COG0800	Aldolase
BIU85_RS10440	COG0129	dihydroxy-acid dehydratase activity
BIU85_RS10445	COG0363	glucosamine-6-phosphate deaminase activity
BIU85_RS10455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BIU85_RS10465	COG0354	folic acid binding
BIU85_RS10480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BIU85_RS10495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BIU85_RS10510	COG4591	ABC-type transport system involved in lipoprotein release permease component
BIU85_RS10535	COG0811	peptide transport
BIU85_RS10540	COG0848	biopolymer transport protein
BIU85_RS10560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BIU85_RS10575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BIU85_RS10605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BIU85_RS10640	COG1530	ribonuclease E activity
BIU85_RS10650	COG0428	transporter
BIU85_RS10685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BIU85_RS10950	COG3279	Response regulator of the LytR AlgR family
BIU85_RS10965	COG4191	Histidine kinase
BIU85_RS10965	COG0784	Response regulator, receiver
BIU85_RS10970	COG0840	transmembrane signaling receptor activity
BIU85_RS11005	COG0840	transmembrane signaling receptor activity
BIU85_RS11015	COG1238	metal cluster binding
BIU85_RS11045	COG1733	regulation of RNA biosynthetic process
BIU85_RS11060	COG1999	signal sequence binding
BIU85_RS11075	COG3590	peptidase
BIU85_RS11160	COG2201	protein-glutamate methylesterase activity
BIU85_RS11165	COG3685	Protein conserved in bacteria
BIU85_RS11275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BIU85_RS11315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BIU85_RS11340	COG0579	oxidoreductase
BIU85_RS11350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BIU85_RS11360	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BIU85_RS11380	COG0243	molybdopterin cofactor binding
BIU85_RS11390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BIU85_RS11395	COG2223	nitrite transmembrane transporter activity
BIU85_RS11400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIU85_RS11410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BIU85_RS11410	COG1648	precorrin-2 dehydrogenase activity
BIU85_RS11420	COG0746	molybdenum cofactor guanylyltransferase activity
BIU85_RS11425	COG0303	'Molybdopterin
BIU85_RS11435	COG0708	Exodeoxyribonuclease III
BIU85_RS11460	COG2124	cytochrome p450
BIU85_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS11480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BIU85_RS11495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIU85_RS11530	COG1024	Enoyl-CoA hydratase
BIU85_RS11530	COG1250	3-hydroxyacyl-CoA dehydrogenase
BIU85_RS11535	COG0183	Belongs to the thiolase family
BIU85_RS11540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BIU85_RS11545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BIU85_RS11565	COG1674	ftsk spoiiie
BIU85_RS11570	COG0492	ferredoxin-NADP+ reductase activity
BIU85_RS11590	COG0542	response to heat
BIU85_RS11610	COG2915	High frequency lysogenization protein hflD homolog
BIU85_RS11645	COG4191	Histidine kinase
BIU85_RS11665	COG0835	chemotaxis
BIU85_RS11665	COG0784	Response regulator, receiver
BIU85_RS11675	COG1558	bacterial-type flagellum-dependent cell motility
BIU85_RS11680	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BIU85_RS11690	COG4787	bacterial-type flagellum-dependent cell motility
BIU85_RS11715	COG3951	Flagellar rod assembly protein muramidase FlgJ
BIU85_RS11715	COG1705	Flagellar rod assembly protein muramidase FlgJ
BIU85_RS11725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BIU85_RS11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BIU85_RS11735	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BIU85_RS11765	COG2201	protein-glutamate methylesterase activity
BIU85_RS11785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIU85_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS11840	COG1677	Flagellar hook-basal body complex protein FliE
BIU85_RS11910	COG1987	bacterial-type flagellum assembly
BIU85_RS11915	COG1684	flagellar biosynthetic protein fliR
BIU85_RS11970	COG0643	Histidine kinase
BIU85_RS11970	COG2198	Histidine kinase
BIU85_RS11970	COG0784	Response regulator, receiver
BIU85_RS12055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BIU85_RS12060	COG1360	Flagellar Motor Protein
BIU85_RS12065	COG1192	Involved in chromosome partitioning
BIU85_RS12070	COG0835	chemotaxis
BIU85_RS12080	COG0745	RESPONSE REGULATOR receiver
BIU85_RS12090	COG0840	transmembrane signaling receptor activity
BIU85_RS12100	COG0840	transmembrane signaling receptor activity
BIU85_RS12105	COG0840	transmembrane signaling receptor activity
BIU85_RS12110	COG0840	transmembrane signaling receptor activity
BIU85_RS12115	COG0840	transmembrane signaling receptor activity
BIU85_RS12120	COG0840	transmembrane signaling receptor activity
BIU85_RS12125	COG0840	transmembrane signaling receptor activity
BIU85_RS12135	COG0840	transmembrane signaling receptor activity
BIU85_RS12165	COG0835	chemotaxis
BIU85_RS12175	COG0840	transmembrane signaling receptor activity
BIU85_RS12205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIU85_RS12235	COG0318	PFAM AMP-dependent synthetase and ligase
BIU85_RS12240	COG1024	Enoyl-CoA hydratase
BIU85_RS12245	COG2198	Histidine kinase
BIU85_RS12245	COG2205	protein histidine kinase activity
BIU85_RS12245	COG0784	Response regulator, receiver
BIU85_RS12250	COG2198	Histidine kinase
BIU85_RS12250	COG0784	Response regulator, receiver
BIU85_RS12250	COG2205	protein histidine kinase activity
BIU85_RS12270	COG3279	Response regulator of the LytR AlgR family
BIU85_RS12295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BIU85_RS12305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BIU85_RS12310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BIU85_RS12320	COG0505	Belongs to the CarA family
BIU85_RS12330	COG2258	MOSC domain
BIU85_RS12335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BIU85_RS12360	COG1024	Enoyl-CoA hydratase
BIU85_RS12395	COG0277	FAD linked oxidase domain protein
BIU85_RS12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BIU85_RS12415	COG0531	amino acid
BIU85_RS12420	COG0531	amino acid
BIU85_RS12460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BIU85_RS12460	COG0140	phosphoribosyl-ATP diphosphatase activity
BIU85_RS12480	COG0131	Imidazoleglycerol-phosphate dehydratase
BIU85_RS12480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BIU85_RS12510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BIU85_RS12520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BIU85_RS12540	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BIU85_RS12605	COG1012	belongs to the aldehyde dehydrogenase family
BIU85_RS12630	COG0697	spore germination
BIU85_RS12635	COG1794	racemase activity, acting on amino acids and derivatives
BIU85_RS12640	COG0477	Major facilitator Superfamily
BIU85_RS12645	COG0671	phosphoesterase, PA-phosphatase related
BIU85_RS12660	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BIU85_RS12665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BIU85_RS12670	COG2203	Gaf domain
BIU85_RS12670	COG3706	GGDEF domain
BIU85_RS12670	COG4251	negative regulation of phosphorylation
BIU85_RS12670	COG5001	Diguanylate cyclase
BIU85_RS12680	COG1472	Belongs to the glycosyl hydrolase 3 family
BIU85_RS12735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BIU85_RS12755	COG0477	Major facilitator Superfamily
BIU85_RS12765	COG1070	Carbohydrate kinase
BIU85_RS12775	COG1501	Belongs to the glycosyl hydrolase 31 family
BIU85_RS12820	COG0800	Aldolase
BIU85_RS12835	COG3734	2-keto-3-deoxy-galactonokinase
BIU85_RS12840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BIU85_RS12850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIU85_RS12865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BIU85_RS12870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BIU85_RS12880	COG0352	thiamine-phosphate diphosphorylase activity
BIU85_RS12880	COG0351	phosphomethylpyrimidine kinase
BIU85_RS12905	COG0583	DNA-binding transcription factor activity
BIU85_RS12910	COG1741	Belongs to the pirin family
BIU85_RS12945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BIU85_RS12960	COG4771	TonB-dependent receptor
BIU85_RS12970	COG1546	Belongs to the CinA family
BIU85_RS12975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BIU85_RS12990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BIU85_RS12995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIU85_RS13005	COG1534	Rna-binding protein
BIU85_RS13020	COG1238	metal cluster binding
BIU85_RS13035	COG2840	Smr protein MutS2
BIU85_RS13095	COG2134	cdp-diacylglycerol pyrophosphatase
BIU85_RS13125	COG1253	flavin adenine dinucleotide binding
BIU85_RS13140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIU85_RS13145	COG0477	Major facilitator Superfamily
BIU85_RS13150	COG1132	(ABC) transporter
BIU85_RS13170	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS13175	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS13180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BIU85_RS13210	COG2244	polysaccharide biosynthetic process
BIU85_RS13225	COG3038	cytochrome b561
BIU85_RS13260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BIU85_RS13280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BIU85_RS13295	COG0784	Response regulator, receiver
BIU85_RS13295	COG4191	Histidine kinase
BIU85_RS13300	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BIU85_RS13350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BIU85_RS13380	COG0583	DNA-binding transcription factor activity
BIU85_RS13395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BIU85_RS13405	COG0077	Prephenate dehydratase
BIU85_RS13405	COG1605	Chorismate mutase
BIU85_RS13415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BIU85_RS13470	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BIU85_RS13480	COG4993	Dehydrogenase
BIU85_RS13500	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BIU85_RS13510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BIU85_RS13545	COG0316	Belongs to the HesB IscA family
BIU85_RS13550	COG0017	Asparaginyl-tRNA synthetase
BIU85_RS13575	COG0288	reversible hydration of carbon dioxide
BIU85_RS13600	COG2925	Exonuclease
BIU85_RS13615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BIU85_RS13635	COG0488	(ABC) transporter
BIU85_RS13640	COG2264	protein methyltransferase activity
BIU85_RS13675	COG0494	nUDIX hydrolase
BIU85_RS13685	COG1024	Enoyl-CoA hydratase
BIU85_RS13695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BIU85_RS13700	COG0659	secondary active sulfate transmembrane transporter activity
BIU85_RS13725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BIU85_RS13730	COG0573	inorganic phosphate transmembrane transporter activity
BIU85_RS13735	COG0581	inorganic phosphate transmembrane transporter activity
BIU85_RS13745	COG0704	Plays a role in the regulation of phosphate uptake
BIU85_RS13765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIU85_RS13780	COG0557	exoribonuclease II activity
BIU85_RS13795	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13800	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13805	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13810	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13815	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13820	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13830	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS13835	COG2226	methyltransferase
BIU85_RS13840	COG1410	methionine synthase
BIU85_RS13840	COG0646	methionine synthase
BIU85_RS13845	COG1410	methionine synthase
BIU85_RS13845	COG0646	methionine synthase
BIU85_RS13855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIU85_RS13865	COG1609	Transcriptional regulator
BIU85_RS13895	COG0386	Belongs to the glutathione peroxidase family
BIU85_RS13905	COG1725	Transcriptional regulator
BIU85_RS13910	COG1131	(ABC) transporter
BIU85_RS13940	COG1253	flavin adenine dinucleotide binding
BIU85_RS13960	COG2850	peptidyl-arginine hydroxylation
BIU85_RS13995	COG1132	(ABC) transporter
BIU85_RS14000	COG0583	DNA-binding transcription factor activity
BIU85_RS14005	COG2274	protein secretion by the type I secretion system
BIU85_RS14030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BIU85_RS14050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BIU85_RS14055	COG1420	regulation of RNA biosynthetic process
BIU85_RS14060	COG0497	DNA recombination
BIU85_RS14070	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIU85_RS14090	COG1404	Belongs to the peptidase S8 family
BIU85_RS14110	COG3706	GGDEF domain
BIU85_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS14140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIU85_RS14155	COG0583	DNA-binding transcription factor activity
BIU85_RS14170	COG0415	Belongs to the DNA photolyase family
BIU85_RS14175	COG0305	Participates in initiation and elongation during chromosome replication
BIU85_RS14185	COG0367	asparagine synthase
BIU85_RS14200	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS14215	COG0084	hydrolase, TatD family'
BIU85_RS14220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BIU85_RS14280	COG0386	Belongs to the glutathione peroxidase family
BIU85_RS14285	COG0339	signal peptide processing
BIU85_RS14320	COG3104	oligopeptide transport
BIU85_RS14350	COG2814	Major facilitator Superfamily
BIU85_RS14355	COG1566	PFAM secretion protein HlyD family protein
BIU85_RS14400	COG4774	siderophore transport
BIU85_RS14415	COG0367	asparagine synthase
BIU85_RS14430	COG1393	Belongs to the ArsC family
BIU85_RS14505	COG0528	UMP kinase activity
BIU85_RS14515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BIU85_RS14520	COG0575	Belongs to the CDS family
BIU85_RS14530	COG0750	zinc metalloprotease
BIU85_RS14585	COG1981	membrane
BIU85_RS14610	COG1695	Transcriptional regulator
BIU85_RS14640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BIU85_RS14650	COG2040	homocysteine
BIU85_RS14655	COG0833	amino acid
BIU85_RS14665	COG0346	lactoylglutathione lyase activity
BIU85_RS14690	COG2878	Part of a membrane complex involved in electron transport
BIU85_RS14705	COG1595	DNA-templated transcription, initiation
BIU85_RS14730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BIU85_RS14745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BIU85_RS14750	COG0251	oxidation-reduction process
BIU85_RS14760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BIU85_RS14760	COG0392	lysyltransferase activity
BIU85_RS14795	COG2814	Major facilitator Superfamily
BIU85_RS14800	COG1902	pentaerythritol trinitrate reductase activity
BIU85_RS14825	COG2824	Alkylphosphonate utilization operon protein PhnA
BIU85_RS14835	COG1047	Peptidyl-prolyl cis-trans
BIU85_RS14880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BIU85_RS14890	COG5487	UPF0391 membrane protein
BIU85_RS14895	COG1451	nucleotide metabolic process
BIU85_RS14915	COG0183	Belongs to the thiolase family
BIU85_RS14950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BIU85_RS14950	COG1793	dna ligase
BIU85_RS14960	COG1793	dna ligase
BIU85_RS14965	COG1201	RNA secondary structure unwinding
BIU85_RS14975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BIU85_RS14980	COG1278	Cold shock
BIU85_RS14985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BIU85_RS14990	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BIU85_RS15000	COG3046	protein related to deoxyribodipyrimidine photolyase
BIU85_RS15005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BIU85_RS15005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BIU85_RS15010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BIU85_RS15015	COG2954	triphosphatase activity
BIU85_RS15065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BIU85_RS15100	COG1024	Enoyl-CoA hydratase
BIU85_RS15105	COG1960	acyl-CoA dehydrogenase activity
BIU85_RS15115	COG1396	sequence-specific DNA binding
BIU85_RS15115	COG3800	Transcriptional regulator
BIU85_RS15125	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BIU85_RS15130	COG3250	beta-galactosidase activity
BIU85_RS15255	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BIU85_RS15310	COG5297	Belongs to the glycosyl hydrolase family 6
BIU85_RS15340	COG3039	Transposase
BIU85_RS15365	COG1309	transcriptional regulator
BIU85_RS15370	COG0436	Aminotransferase
BIU85_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS15380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BIU85_RS15430	COG0583	DNA-binding transcription factor activity
BIU85_RS15650	COG0534	Mate efflux family protein
BIU85_RS15680	COG2070	2-Nitropropane dioxygenase
BIU85_RS15695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BIU85_RS15700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BIU85_RS15710	COG3534	alpha-L-arabinofuranosidase
BIU85_RS15740	COG4191	Histidine kinase
BIU85_RS15740	COG0784	Response regulator, receiver
BIU85_RS15745	COG2205	protein histidine kinase activity
BIU85_RS15745	COG3850	Histidine kinase
BIU85_RS15745	COG4999	Histidine kinase
BIU85_RS15745	COG3437	response regulator, receiver
BIU85_RS15750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BIU85_RS15760	COG2205	protein histidine kinase activity
BIU85_RS15765	COG5507	3-demethylubiquinone-9 3-methyltransferase
BIU85_RS15775	COG4771	TonB-dependent receptor
BIU85_RS15800	COG2172	sigma factor antagonist activity
BIU85_RS15805	COG1366	Belongs to the anti-sigma-factor antagonist family
BIU85_RS15810	COG1366	Belongs to the anti-sigma-factor antagonist family
BIU85_RS15820	COG1902	pentaerythritol trinitrate reductase activity
BIU85_RS15830	COG0326	Molecular chaperone. Has ATPase activity
BIU85_RS15835	COG2207	Transcriptional regulator
BIU85_RS15850	COG3152	Membrane
BIU85_RS15870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BIU85_RS15875	COG1845	cytochrome c oxidase, subunit III
BIU85_RS15880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BIU85_RS15910	COG0196	riboflavin kinase activity
BIU85_RS15940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BIU85_RS15945	COG0824	Thioesterase
BIU85_RS15950	COG1024	Enoyl-CoA hydratase
BIU85_RS15955	COG1946	Acyl-CoA thioesterase
BIU85_RS15975	COG1595	DNA-templated transcription, initiation
BIU85_RS16040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BIU85_RS16065	COG2197	response regulator
BIU85_RS16085	COG2894	cell division
BIU85_RS16100	COG5002	protein histidine kinase activity
BIU85_RS16105	COG0745	RESPONSE REGULATOR receiver
BIU85_RS16120	COG2194	sulfuric ester hydrolase activity
BIU85_RS16140	COG2814	Major facilitator Superfamily
BIU85_RS16170	COG0656	L-ascorbic acid biosynthetic process
BIU85_RS16175	COG0753	catalase activity
BIU85_RS16190	COG2207	Transcriptional regulator
BIU85_RS16190	COG1917	Cupin 2, conserved barrel domain protein
BIU85_RS16215	COG0823	Involved in the tonB-independent uptake of proteins
BIU85_RS16215	COG1506	peptidase
BIU85_RS16225	COG1297	OPT oligopeptide transporter protein
BIU85_RS16255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BIU85_RS16280	COG2080	2 iron, 2 sulfur cluster binding
BIU85_RS16285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BIU85_RS16290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BIU85_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS16340	COG3537	Alpha-1,2-mannosidase
BIU85_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS16355	COG3387	PFAM Glycoside hydrolase 15-related
BIU85_RS16370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BIU85_RS16405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BIU85_RS16475	COG0308	aminopeptidase N
BIU85_RS16490	COG0330	HflC and HflK could
BIU85_RS16495	COG0330	HflC and HflK could
BIU85_RS16515	COG0678	peroxiredoxin activity
BIU85_RS16525	COG4953	penicillin-binding protein 1C
BIU85_RS16550	COG2373	Large extracellular alpha-helical protein
BIU85_RS16585	COG3609	addiction module antidote protein, CC2985 family
BIU85_RS16605	COG3829	transcription factor binding
BIU85_RS16700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BIU85_RS16705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BIU85_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS16725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BIU85_RS16730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIU85_RS16740	COG1399	metal-binding, possibly nucleic acid-binding protein
BIU85_RS16770	COG0714	Associated with various cellular activities
BIU85_RS16790	COG0537	adenosine 5'-monophosphoramidase activity
BIU85_RS16855	COG2003	Belongs to the UPF0758 family
BIU85_RS16920	COG0314	molybdopterin synthase activity
BIU85_RS16925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BIU85_RS16945	COG1234	tRNA 3'-trailer cleavage
BIU85_RS16955	COG0859	PFAM glycosyl transferase family 9
BIU85_RS16970	COG0631	protein serine/threonine phosphatase activity
BIU85_RS16975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BIU85_RS17080	COG0473	3-isopropylmalate dehydrogenase activity
BIU85_RS17095	COG4783	chaperone-mediated protein folding
BIU85_RS17100	COG0745	RESPONSE REGULATOR receiver
BIU85_RS17110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BIU85_RS17120	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS17125	COG0671	phosphoesterase, PA-phosphatase related
BIU85_RS17130	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BIU85_RS17140	COG3291	Pkd domain containing protein
BIU85_RS17145	COG2833	Protein of unknown function (DUF455)
BIU85_RS17165	COG0285	dihydrofolate synthase activity
BIU85_RS17180	COG0406	alpha-ribazole phosphatase activity
BIU85_RS17205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BIU85_RS17210	COG4208	sulfate ABC transporter
BIU85_RS17215	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BIU85_RS17220	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BIU85_RS17255	COG1902	pentaerythritol trinitrate reductase activity
BIU85_RS17255	COG0446	pyridine nucleotide-disulphide oxidoreductase
BIU85_RS17280	COG0625	glutathione transferase activity
BIU85_RS17290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BIU85_RS17295	COG1217	gtp-binding protein TYPA
BIU85_RS17305	COG0154	amidase activity
BIU85_RS17315	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BIU85_RS17350	COG0201	protein transport
BIU85_RS17435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BIU85_RS17505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BIU85_RS17510	COG0250	Participates in transcription elongation, termination and antitermination
BIU85_RS17515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BIU85_RS17545	COG0012	GTP binding
BIU85_RS17550	COG0193	aminoacyl-tRNA hydrolase activity
BIU85_RS17560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BIU85_RS17610	COG0521	Mo-molybdopterin cofactor biosynthetic process
BIU85_RS17630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BIU85_RS17660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BIU85_RS17665	COG1404	Belongs to the peptidase S8 family
BIU85_RS17675	COG1404	Belongs to the peptidase S8 family
BIU85_RS17680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BIU85_RS17745	COG0778	Nitroreductase
BIU85_RS17750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIU85_RS17750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIU85_RS17775	COG2890	protein-(glutamine-N5) methyltransferase activity
BIU85_RS17785	COG3634	alkyl hydroperoxide reductase activity
BIU85_RS17790	COG0583	DNA-binding transcription factor activity
BIU85_RS17795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BIU85_RS17820	COG2197	response regulator
BIU85_RS17825	COG0784	Response regulator, receiver
BIU85_RS17825	COG2205	protein histidine kinase activity
BIU85_RS17825	COG5002	protein histidine kinase activity
BIU85_RS17855	COG0697	spore germination
BIU85_RS17885	COG3386	PFAM SMP-30 Gluconolaconase
BIU85_RS17905	COG1024	Enoyl-CoA hydratase
BIU85_RS17915	COG0318	PFAM AMP-dependent synthetase and ligase
BIU85_RS17920	COG0583	DNA-binding transcription factor activity
BIU85_RS17925	COG3384	dioxygenase
BIU85_RS17955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BIU85_RS17960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BIU85_RS17970	COG2096	Adenosyltransferase
BIU85_RS17975	COG0123	including yeast histone deacetylase and acetoin utilization protein
BIU85_RS18005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BIU85_RS18040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BIU85_RS18050	COG0642	Histidine kinase
BIU85_RS18065	COG4181	ATPase activity
BIU85_RS18075	COG2175	clavaminate synthase activity
BIU85_RS18085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BIU85_RS18110	COG4771	TonB-dependent receptor
BIU85_RS18125	COG0667	Aldo Keto reductase
BIU85_RS18135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BIU85_RS18150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIU85_RS18250	COG0366	Alpha amylase catalytic
BIU85_RS18295	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS18295	COG3321	synthase
BIU85_RS18295	COG0604	alcohol dehydrogenase
BIU85_RS18310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BIU85_RS18325	COG0494	nUDIX hydrolase
BIU85_RS18340	COG0739	heme binding
BIU85_RS18365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BIU85_RS18370	COG1181	Belongs to the D-alanine--D-alanine ligase family
BIU85_RS18395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BIU85_RS18410	COG3116	cell division
BIU85_RS18470	COG1988	membrane-bound metal-dependent
BIU85_RS18475	COG0277	FAD linked oxidase domain protein
BIU85_RS18485	COG0745	RESPONSE REGULATOR receiver
BIU85_RS18490	COG2205	protein histidine kinase activity
BIU85_RS18500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BIU85_RS18505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BIU85_RS18530	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BIU85_RS18560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BIU85_RS18560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BIU85_RS18585	COG0488	(ABC) transporter
BIU85_RS18590	COG0242	peptide deformylase activity
BIU85_RS18595	COG1393	Belongs to the ArsC family
BIU85_RS18610	COG0457	Tetratricopeptide repeat
BIU85_RS18670	COG2188	Transcriptional regulator
BIU85_RS18680	COG1450	Type ii and iii secretion system protein
BIU85_RS18695	COG3166	PFAM Fimbrial assembly family protein
BIU85_RS18700	COG3156	type II secretion system protein K
BIU85_RS18705	COG4795	General secretion pathway protein
BIU85_RS18710	COG2165	general secretion pathway protein
BIU85_RS18715	COG4970	Tfp pilus assembly protein FimT
BIU85_RS18720	COG2165	general secretion pathway protein
BIU85_RS18730	COG1459	type II secretion system
BIU85_RS18735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BIU85_RS18740	COG1404	Belongs to the peptidase S8 family
BIU85_RS18755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BIU85_RS18755	COG0047	phosphoribosylformylglycinamidine synthase activity
BIU85_RS18760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BIU85_RS18765	COG4974	Belongs to the 'phage' integrase family
BIU85_RS18780	COG0795	lipopolysaccharide-transporting ATPase activity
BIU85_RS18850	COG1183	phosphatidylcholine synthase activity
BIU85_RS18875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BIU85_RS18880	COG1127	ABC transporter
BIU85_RS18885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BIU85_RS18885	COG3218	ABC-type transport auxiliary lipoprotein component
BIU85_RS18930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIU85_RS18935	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BIU85_RS18935	COG0662	Cupin 2, conserved barrel domain protein
BIU85_RS18960	COG2086	electron transfer activity
BIU85_RS18970	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BIU85_RS18970	COG0662	Cupin 2, conserved barrel domain protein
BIU85_RS18980	COG0463	Glycosyl transferase, family 2
BIU85_RS19005	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BIU85_RS19020	COG0438	transferase activity, transferring glycosyl groups
BIU85_RS19045	COG0626	cystathionine gamma-synthase activity
BIU85_RS19075	COG0625	glutathione transferase activity
BIU85_RS19090	COG0513	Belongs to the DEAD box helicase family
BIU85_RS19095	COG0720	synthase
BIU85_RS19110	COG1956	GAF domain-containing protein
BIU85_RS19140	COG0339	signal peptide processing
BIU85_RS19145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BIU85_RS19200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BIU85_RS19210	COG1136	(ABC) transporter
BIU85_RS19215	COG0577	efflux transmembrane transporter activity
BIU85_RS19235	COG4191	Histidine kinase
BIU85_RS19300	COG0356	it plays a direct role in the translocation of protons across the membrane
BIU85_RS19315	COG1228	amidohydrolase
BIU85_RS19320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BIU85_RS19330	COG0508	dehydrogenase complex catalyzes the overall conversion of
BIU85_RS19360	COG2011	ABC-type metal ion transport system permease component
BIU85_RS19370	COG0697	spore germination
BIU85_RS19400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BIU85_RS19405	COG1187	pseudouridine synthase activity
BIU85_RS19410	COG2813	Specifically methylates the guanine in position
BIU85_RS19430	COG5002	protein histidine kinase activity
BIU85_RS19515	COG0842	Transport permease protein
BIU85_RS19520	COG1131	(ABC) transporter
BIU85_RS19525	COG0025	NhaP-type Na H and K H
BIU85_RS19530	COG3795	YCII-related domain
BIU85_RS19535	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BIU85_RS19540	COG1573	uracil-dna glycosylase
BIU85_RS19555	COG3384	dioxygenase
BIU85_RS19560	COG0583	DNA-binding transcription factor activity
BIU85_RS19570	COG0667	Aldo Keto reductase
BIU85_RS19580	COG3590	peptidase
BIU85_RS19595	COG0531	amino acid
BIU85_RS19610	COG2972	Histidine kinase
BIU85_RS19635	COG1335	isochorismatase
BIU85_RS19640	COG3685	Protein conserved in bacteria
BIU85_RS19645	COG3685	Protein conserved in bacteria
BIU85_RS19650	COG3546	catalase activity
BIU85_RS19680	COG2204	response regulator
BIU85_RS19690	COG1271	oxidase subunit
BIU85_RS19695	COG1294	oxidase, subunit
BIU85_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS19715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BIU85_RS19735	COG1132	(ABC) transporter
BIU85_RS19750	COG1063	alcohol dehydrogenase
BIU85_RS19790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BIU85_RS19850	COG0251	oxidation-reduction process
BIU85_RS19870	COG0667	Aldo Keto reductase
BIU85_RS19875	COG0583	DNA-binding transcription factor activity
BIU85_RS19895	COG4251	negative regulation of phosphorylation
BIU85_RS19895	COG5001	Diguanylate cyclase
BIU85_RS19895	COG2203	Gaf domain
BIU85_RS19895	COG3706	GGDEF domain
BIU85_RS19935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIU85_RS19945	COG1560	Kdo2-lipid A biosynthetic process
BIU85_RS19955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BIU85_RS19990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BIU85_RS19990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIU85_RS20000	COG0242	peptide deformylase activity
BIU85_RS20005	COG1652	LysM domain
BIU85_RS20010	COG0758	DNA mediated transformation
BIU85_RS20030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BIU85_RS20030	COG1754	DNA topoisomerase type I activity
BIU85_RS20050	COG5001	Diguanylate cyclase
BIU85_RS20050	COG3706	GGDEF domain
BIU85_RS20050	COG4251	negative regulation of phosphorylation
BIU85_RS20050	COG2203	Gaf domain
BIU85_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS20065	COG0616	signal peptide processing
BIU85_RS20070	COG0534	Mate efflux family protein
BIU85_RS20085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BIU85_RS20105	COG1252	NADH dehydrogenase
BIU85_RS20110	COG2860	membrane
BIU85_RS20115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIU85_RS20125	COG3437	response regulator, receiver
BIU85_RS20130	COG2177	Part of the ABC transporter FtsEX involved in
BIU85_RS20135	COG2884	Cell division ATP-binding protein ftsE
BIU85_RS20145	COG3118	belongs to the thioredoxin family
BIU85_RS20150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BIU85_RS20195	COG1473	amidohydrolase
BIU85_RS20200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIU85_RS20240	COG4941	Belongs to the sigma-70 factor family
BIU85_RS20245	COG5383	Protein conserved in bacteria
BIU85_RS20285	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BIU85_RS20290	COG3409	Peptidoglycan-binding domain 1 protein
BIU85_RS20290	COG3501	Rhs element vgr protein
BIU85_RS20305	COG3023	N-Acetylmuramoyl-L-alanine amidase
BIU85_RS20315	COG4948	Mandelate Racemase Muconate Lactonizing
BIU85_RS20325	COG0531	amino acid
BIU85_RS20340	COG4682	membrane
BIU85_RS20345	COG2133	pyrroloquinoline quinone binding
BIU85_RS20355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BIU85_RS20370	COG1610	YqeY-like protein
BIU85_RS20375	COG1295	ribonuclease BN
BIU85_RS20380	COG0358	DNA primase activity
BIU85_RS20430	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BIU85_RS20445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BIU85_RS20490	COG0739	heme binding
BIU85_RS20515	COG0708	Exodeoxyribonuclease III
BIU85_RS20530	COG1192	Involved in chromosome partitioning
BIU85_RS20535	COG1475	DNA binding
BIU85_RS20555	COG0463	Glycosyl transferase, family 2
BIU85_RS20580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BIU85_RS20605	COG4221	oxidoreductase activity
BIU85_RS20610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BIU85_RS20610	COG2755	lipolytic protein G-D-S-L family
BIU85_RS20625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BIU85_RS20630	COG1166	arginine decarboxylase activity
BIU85_RS20655	COG2960	long-chain fatty acid transporting porin activity
BIU85_RS20660	COG0606	chelatase, subunit chli
BIU85_RS20675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BIU85_RS20710	COG1690	Belongs to the RtcB family
BIU85_RS20750	COG1090	epimerase
BIU85_RS20755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BIU85_RS20770	COG0642	Histidine kinase
BIU85_RS20790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BIU85_RS20820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BIU85_RS20825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BIU85_RS20845	COG2197	response regulator
BIU85_RS20850	COG4585	Histidine kinase
BIU85_RS20870	COG1136	(ABC) transporter
BIU85_RS20895	COG0697	spore germination
BIU85_RS20920	COG0180	Tryptophanyl-tRNA synthetase
BIU85_RS20925	COG3237	CsbD-like
BIU85_RS21000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BIU85_RS21000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BIU85_RS21040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIU85_RS21070	COG1199	ATP-dependent helicase activity
BIU85_RS21135	COG0625	glutathione transferase activity
BIU85_RS21170	COG4555	ABC transporter
BIU85_RS21180	COG1476	TRANSCRIPTIONal
BIU85_RS21195	COG1230	cation diffusion facilitator family transporter
BIU85_RS21205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BIU85_RS21210	COG1131	(ABC) transporter
BIU85_RS21215	COG0842	Transport permease protein
BIU85_RS21225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BIU85_RS21240	COG1607	acyl-coa hydrolase
BIU85_RS21250	COG0716	FMN binding
BIU85_RS21255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BIU85_RS21265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BIU85_RS21275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BIU85_RS21275	COG0045	succinate-CoA ligase (ADP-forming) activity
BIU85_RS21275	COG1042	CoA-binding domain protein
BIU85_RS21285	COG2239	Acts as a magnesium transporter
BIU85_RS21300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BIU85_RS21305	COG3387	PFAM Glycoside hydrolase 15-related
BIU85_RS21325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BIU85_RS21335	COG0463	Glycosyl transferase, family 2
BIU85_RS21345	COG3039	Transposase
BIU85_RS21360	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS21390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BIU85_RS21405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIU85_RS21545	COG4717	serine-type aminopeptidase activity
BIU85_RS21575	COG3039	Transposase
BIU85_RS21605	COG0464	growth
BIU85_RS21630	COG0210	DNA helicase
BIU85_RS21740	COG3039	Transposase
BIU85_RS21795	COG0210	DNA helicase
BIU85_RS21805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS21810	COG0583	DNA-binding transcription factor activity
BIU85_RS21815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BIU85_RS21825	COG2159	amidohydrolase
BIU85_RS21915	COG2091	lysine biosynthetic process via aminoadipic acid
BIU85_RS21975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BIU85_RS21985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BIU85_RS21990	COG3162	membrane
BIU85_RS22025	COG3507	Belongs to the glycosyl hydrolase 43 family
BIU85_RS22040	COG1028	Short-chain dehydrogenase reductase Sdr
BIU85_RS22045	COG0179	Fumarylacetoacetate (FAA) hydrolase
BIU85_RS22050	COG4948	Mandelate Racemase Muconate Lactonizing
BIU85_RS22060	COG3254	rhamnose metabolic process
BIU85_RS22065	COG0738	Major facilitator superfamily
BIU85_RS22070	COG1414	Transcriptional regulator
BIU85_RS22090	COG2205	protein histidine kinase activity
BIU85_RS22090	COG0784	Response regulator, receiver
BIU85_RS22100	COG3459	Glycosyltransferase 36 associated
BIU85_RS22105	COG2211	Major facilitator Superfamily
BIU85_RS22110	COG3265	gluconokinase activity
BIU85_RS22115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIU85_RS22140	COG2911	Protein conserved in bacteria
BIU85_RS22145	COG0729	surface antigen
BIU85_RS22165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BIU85_RS22175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BIU85_RS22175	COG0519	Catalyzes the synthesis of GMP from XMP
BIU85_RS22190	COG0805	protein transport
BIU85_RS22210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BIU85_RS22260	COG3661	Belongs to the glycosyl hydrolase 67 family
BIU85_RS22270	COG4948	Mandelate Racemase Muconate Lactonizing
BIU85_RS22280	COG1472	Belongs to the glycosyl hydrolase 3 family
BIU85_RS22285	COG0246	Mannitol dehydrogenase
BIU85_RS22315	COG3386	PFAM SMP-30 Gluconolaconase
BIU85_RS22335	COG3250	beta-galactosidase activity
BIU85_RS22345	COG3693	PFAM glycoside hydrolase, family 10
BIU85_RS22360	COG2211	Major facilitator Superfamily
BIU85_RS22400	COG2937	Belongs to the GPAT DAPAT family
BIU85_RS22435	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BIU85_RS22455	COG0210	DNA helicase
BIU85_RS22485	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BIU85_RS22530	COG3135	benzoate transporter
BIU85_RS22555	COG0676	glucose-6-phosphate 1-epimerase activity
BIU85_RS22585	COG0730	response to heat
BIU85_RS22610	COG0302	gtp cyclohydrolase
BIU85_RS22625	COG1566	PFAM secretion protein HlyD family protein
BIU85_RS22635	COG1289	transmembrane transporter activity
BIU85_RS22640	COG0477	Major facilitator Superfamily
BIU85_RS22650	COG0583	DNA-binding transcription factor activity
BIU85_RS22655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIU85_RS22735	COG0564	pseudouridine synthase activity
BIU85_RS22785	COG1074	ATP-dependent DNA helicase activity
BIU85_RS22790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BIU85_RS22825	COG1127	ABC transporter
BIU85_RS22830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BIU85_RS22835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BIU85_RS22850	COG2853	Lipoprotein
BIU85_RS22860	COG0386	Belongs to the glutathione peroxidase family
BIU85_RS22870	COG1322	Protein conserved in bacteria
BIU85_RS22880	COG0604	alcohol dehydrogenase
BIU85_RS22885	COG0583	DNA-binding transcription factor activity
BIU85_RS22900	COG0531	amino acid
BIU85_RS22910	COG4206	TonB-dependent receptor
BIU85_RS22920	COG3706	GGDEF domain
BIU85_RS22925	COG3835	regulator
BIU85_RS22930	COG1929	Belongs to the glycerate kinase type-1 family
BIU85_RS22935	COG2271	Major facilitator Superfamily
BIU85_RS22960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BIU85_RS22970	COG0861	Integral membrane protein TerC family
BIU85_RS23000	COG0584	glycerophosphoryl diester phosphodiesterase
BIU85_RS23015	COG0671	phosphoesterase, PA-phosphatase related
BIU85_RS23030	COG0726	polysaccharide deacetylase
BIU85_RS23035	COG0706	membrane insertase activity
BIU85_RS23055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BIU85_RS23145	COG3279	Response regulator of the LytR AlgR family
BIU85_RS23420	COG0489	protein tyrosine kinase activity
BIU85_RS23630	COG3437	response regulator, receiver
BIU85_RS23635	COG2205	protein histidine kinase activity
BIU85_RS23635	COG0784	Response regulator, receiver