locus-tag	class	description
XCR_RS00020	COG0187	DNA topoisomerase II activity
XCR_RS00030	COG0501	Belongs to the peptidase M48B family
XCR_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCR_RS00110	COG0793	Belongs to the peptidase S41A family
XCR_RS00115	COG4942	peptidase
XCR_RS00125	COG2234	aminopeptidase activity
XCR_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_RS00150	COG1064	alcohol dehydrogenase
XCR_RS00165	COG0493	'glutamate synthase
XCR_RS00170	COG0069	glutamate synthase activity
XCR_RS00170	COG0070	glutamate synthase
XCR_RS00170	COG0067	glutamate synthase
XCR_RS00195	COG1741	Belongs to the pirin family
XCR_RS00200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCR_RS00220	COG0583	DNA-binding transcription factor activity
XCR_RS00270	COG1205	dead DEAH box helicase
XCR_RS00270	COG1111	helicase
XCR_RS00275	COG3177	Filamentation induced by cAMP protein fic
XCR_RS00280	COG1272	protein, Hemolysin III
XCR_RS00345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XCR_RS00355	COG3237	CsbD-like
XCR_RS00405	COG0628	permease
XCR_RS00410	COG0657	acetylesterase activity
XCR_RS00420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_RS00425	COG0477	Major facilitator Superfamily
XCR_RS00465	COG0714	Associated with various cellular activities
XCR_RS00505	COG4772	TonB-dependent receptor
XCR_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
XCR_RS00550	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCR_RS00555	COG4585	Histidine kinase
XCR_RS00560	COG2197	response regulator
XCR_RS00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCR_RS00640	COG2801	Transposase and inactivated derivatives
XCR_RS00645	COG2963	transposase activity
XCR_RS00670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCR_RS00690	COG0805	protein transport
XCR_RS00705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCR_RS00705	COG0519	Catalyzes the synthesis of GMP from XMP
XCR_RS00710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCR_RS00725	COG0729	surface antigen
XCR_RS00730	COG2911	Protein conserved in bacteria
XCR_RS00750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_RS00755	COG3265	gluconokinase activity
XCR_RS00760	COG2211	Major facilitator Superfamily
XCR_RS00765	COG3459	Glycosyltransferase 36 associated
XCR_RS00770	COG3039	Transposase
XCR_RS00775	COG2205	protein histidine kinase activity
XCR_RS00775	COG0784	Response regulator, receiver
XCR_RS00795	COG1414	Transcriptional regulator
XCR_RS00800	COG0738	Major facilitator superfamily
XCR_RS00805	COG3254	rhamnose metabolic process
XCR_RS00810	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_RS00815	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCR_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS00835	COG3507	Belongs to the glycosyl hydrolase 43 family
XCR_RS00855	COG3039	Transposase
XCR_RS00880	COG3162	membrane
XCR_RS00885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCR_RS00895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCR_RS00905	COG1940	carbohydrate kinase activity
XCR_RS00965	COG2091	lysine biosynthetic process via aminoadipic acid
XCR_RS01025	COG2159	amidohydrolase
XCR_RS01035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCR_RS01040	COG0583	DNA-binding transcription factor activity
XCR_RS01045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS01055	COG0210	DNA helicase
XCR_RS01125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCR_RS01140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XCR_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS01185	COG0463	Glycosyl transferase, family 2
XCR_RS01195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCR_RS01215	COG3387	PFAM Glycoside hydrolase 15-related
XCR_RS01220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCR_RS01235	COG2239	Acts as a magnesium transporter
XCR_RS01245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCR_RS01245	COG0045	succinate-CoA ligase (ADP-forming) activity
XCR_RS01245	COG1042	CoA-binding domain protein
XCR_RS01255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCR_RS01260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCR_RS01280	COG1607	acyl-coa hydrolase
XCR_RS01295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCR_RS01305	COG0842	Transport permease protein
XCR_RS01310	COG1131	(ABC) transporter
XCR_RS01315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCR_RS01340	COG1476	TRANSCRIPTIONal
XCR_RS01350	COG4555	ABC transporter
XCR_RS01385	COG0625	glutathione transferase activity
XCR_RS01445	COG1199	ATP-dependent helicase activity
XCR_RS01470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCR_RS01500	COG3228	Belongs to the MtfA family
XCR_RS01510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCR_RS01510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCR_RS01590	COG3237	CsbD-like
XCR_RS01595	COG0180	Tryptophanyl-tRNA synthetase
XCR_RS01615	COG0697	spore germination
XCR_RS01640	COG1136	(ABC) transporter
XCR_RS01650	COG4585	Histidine kinase
XCR_RS01655	COG2197	response regulator
XCR_RS01675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCR_RS01680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCR_RS01705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCR_RS01725	COG0642	Histidine kinase
XCR_RS01740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_RS01745	COG1090	epimerase
XCR_RS01785	COG1690	Belongs to the RtcB family
XCR_RS01820	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCR_RS01835	COG0606	chelatase, subunit chli
XCR_RS01840	COG2960	long-chain fatty acid transporting porin activity
XCR_RS01865	COG1166	arginine decarboxylase activity
XCR_RS01870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCR_RS01880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCR_RS01880	COG2755	lipolytic protein G-D-S-L family
XCR_RS01885	COG4221	oxidoreductase activity
XCR_RS01910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCR_RS01935	COG0463	Glycosyl transferase, family 2
XCR_RS01955	COG1475	DNA binding
XCR_RS01960	COG1192	Involved in chromosome partitioning
XCR_RS01975	COG0708	Exodeoxyribonuclease III
XCR_RS01980	COG2223	nitrite transmembrane transporter activity
XCR_RS01995	COG0739	heme binding
XCR_RS02040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCR_RS02055	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCR_RS02105	COG0358	DNA primase activity
XCR_RS02110	COG1295	ribonuclease BN
XCR_RS02115	COG1610	YqeY-like protein
XCR_RS02130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCR_RS02140	COG2133	pyrroloquinoline quinone binding
XCR_RS02145	COG4682	membrane
XCR_RS02160	COG0531	amino acid
XCR_RS02170	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_RS02180	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCR_RS02195	COG3409	Peptidoglycan-binding domain 1 protein
XCR_RS02195	COG3501	Rhs element vgr protein
XCR_RS02200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCR_RS02240	COG5383	Protein conserved in bacteria
XCR_RS02245	COG4941	Belongs to the sigma-70 factor family
XCR_RS02275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_RS02280	COG1473	amidohydrolase
XCR_RS02325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCR_RS02330	COG3118	belongs to the thioredoxin family
XCR_RS02340	COG2884	Cell division ATP-binding protein ftsE
XCR_RS02345	COG2177	Part of the ABC transporter FtsEX involved in
XCR_RS02350	COG2201	protein-glutamate methylesterase activity
XCR_RS02360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCR_RS02365	COG2860	membrane
XCR_RS02370	COG1252	NADH dehydrogenase
XCR_RS02385	COG0625	glutathione transferase activity
XCR_RS02390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCR_RS02405	COG0534	Mate efflux family protein
XCR_RS02410	COG0616	signal peptide processing
XCR_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS02425	COG2203	Gaf domain
XCR_RS02425	COG5001	Diguanylate cyclase
XCR_RS02425	COG3706	GGDEF domain
XCR_RS02425	COG4251	negative regulation of phosphorylation
XCR_RS02445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCR_RS02445	COG1754	DNA topoisomerase type I activity
XCR_RS02465	COG0758	DNA mediated transformation
XCR_RS02470	COG1652	LysM domain
XCR_RS02475	COG0242	peptide deformylase activity
XCR_RS02485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCR_RS02485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCR_RS02520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCR_RS02530	COG1560	Kdo2-lipid A biosynthetic process
XCR_RS02540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCR_RS02560	COG2203	Gaf domain
XCR_RS02560	COG5001	Diguanylate cyclase
XCR_RS02560	COG4251	negative regulation of phosphorylation
XCR_RS02560	COG3706	GGDEF domain
XCR_RS02580	COG0583	DNA-binding transcription factor activity
XCR_RS02585	COG0667	Aldo Keto reductase
XCR_RS02605	COG0251	oxidation-reduction process
XCR_RS02620	COG1131	(ABC) transporter
XCR_RS02660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_RS02685	COG1063	alcohol dehydrogenase
XCR_RS02700	COG1132	(ABC) transporter
XCR_RS02720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCR_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS02740	COG1294	oxidase, subunit
XCR_RS02745	COG1271	oxidase subunit
XCR_RS02755	COG2204	response regulator
XCR_RS02785	COG3546	catalase activity
XCR_RS02790	COG3685	Protein conserved in bacteria
XCR_RS02795	COG3685	Protein conserved in bacteria
XCR_RS02800	COG1335	isochorismatase
XCR_RS02815	COG2972	Histidine kinase
XCR_RS02830	COG0531	amino acid
XCR_RS02845	COG3590	peptidase
XCR_RS02855	COG0667	Aldo Keto reductase
XCR_RS02865	COG0583	DNA-binding transcription factor activity
XCR_RS02870	COG3384	dioxygenase
XCR_RS02880	COG1573	uracil-dna glycosylase
XCR_RS02885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCR_RS02890	COG3795	YCII-related domain
XCR_RS02895	COG0025	NhaP-type Na H and K H
XCR_RS02900	COG1131	(ABC) transporter
XCR_RS02905	COG0842	Transport permease protein
XCR_RS02985	COG5002	protein histidine kinase activity
XCR_RS03005	COG2813	Specifically methylates the guanine in position
XCR_RS03010	COG1187	pseudouridine synthase activity
XCR_RS03015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCR_RS03045	COG0697	spore germination
XCR_RS03055	COG2011	ABC-type metal ion transport system permease component
XCR_RS03085	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCR_RS03095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_RS03100	COG1228	amidohydrolase
XCR_RS03115	COG0356	it plays a direct role in the translocation of protons across the membrane
XCR_RS03175	COG4191	Histidine kinase
XCR_RS03195	COG0577	efflux transmembrane transporter activity
XCR_RS03200	COG1136	(ABC) transporter
XCR_RS03210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCR_RS03260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCR_RS03265	COG0339	signal peptide processing
XCR_RS03295	COG1956	GAF domain-containing protein
XCR_RS03310	COG0720	synthase
XCR_RS03315	COG0513	Belongs to the DEAD box helicase family
XCR_RS03325	COG0625	glutathione transferase activity
XCR_RS03355	COG0626	cystathionine gamma-synthase activity
XCR_RS03380	COG0438	transferase activity, transferring glycosyl groups
XCR_RS03395	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCR_RS03400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_RS03420	COG0463	Glycosyl transferase, family 2
XCR_RS03425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XCR_RS03440	COG2086	electron transfer activity
XCR_RS03470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCR_RS03505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCR_RS03505	COG3218	ABC-type transport auxiliary lipoprotein component
XCR_RS03510	COG1127	ABC transporter
XCR_RS03515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCR_RS03540	COG1183	phosphatidylcholine synthase activity
XCR_RS03600	COG0795	lipopolysaccharide-transporting ATPase activity
XCR_RS03615	COG4974	Belongs to the 'phage' integrase family
XCR_RS03620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCR_RS03625	COG0047	phosphoribosylformylglycinamidine synthase activity
XCR_RS03625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCR_RS03640	COG1404	Belongs to the peptidase S8 family
XCR_RS03645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCR_RS03650	COG1459	type II secretion system
XCR_RS03655	COG2165	general secretion pathway protein
XCR_RS03660	COG4970	Tfp pilus assembly protein FimT
XCR_RS03665	COG2165	general secretion pathway protein
XCR_RS03670	COG4795	General secretion pathway protein
XCR_RS03675	COG3156	type II secretion system protein K
XCR_RS03680	COG3166	PFAM Fimbrial assembly family protein
XCR_RS03695	COG1450	Type ii and iii secretion system protein
XCR_RS03705	COG2188	Transcriptional regulator
XCR_RS03765	COG1215	transferase activity, transferring glycosyl groups
XCR_RS03770	COG1215	transferase activity, transferring glycosyl groups
XCR_RS03775	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XCR_RS03780	COG0457	Tetratricopeptide repeat
XCR_RS03795	COG1393	Belongs to the ArsC family
XCR_RS03800	COG0242	peptide deformylase activity
XCR_RS03805	COG0488	(ABC) transporter
XCR_RS03830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCR_RS03830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCR_RS03860	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCR_RS03880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCR_RS03885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCR_RS03895	COG2205	protein histidine kinase activity
XCR_RS03900	COG0745	RESPONSE REGULATOR receiver
XCR_RS03905	COG0277	FAD linked oxidase domain protein
XCR_RS03910	COG1988	membrane-bound metal-dependent
XCR_RS03955	COG3116	cell division
XCR_RS03970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCR_RS03995	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCR_RS04000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCR_RS04025	COG0739	heme binding
XCR_RS04045	COG0494	nUDIX hydrolase
XCR_RS04060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCR_RS04075	COG3321	synthase
XCR_RS04075	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS04075	COG0604	alcohol dehydrogenase
XCR_RS04105	COG0366	Alpha amylase catalytic
XCR_RS04185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCR_RS04195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCR_RS04200	COG0667	Aldo Keto reductase
XCR_RS04210	COG4771	TonB-dependent receptor
XCR_RS04245	COG2175	clavaminate synthase activity
XCR_RS04255	COG4181	ATPase activity
XCR_RS04270	COG0642	Histidine kinase
XCR_RS04280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCR_RS04315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCR_RS04345	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCR_RS04350	COG2096	Adenosyltransferase
XCR_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_RS04395	COG3384	dioxygenase
XCR_RS04400	COG0583	DNA-binding transcription factor activity
XCR_RS04405	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_RS04415	COG1024	Enoyl-CoA hydratase
XCR_RS04435	COG3386	PFAM SMP-30 Gluconolaconase
XCR_RS04465	COG0697	spore germination
XCR_RS04495	COG2205	protein histidine kinase activity
XCR_RS04495	COG5002	protein histidine kinase activity
XCR_RS04495	COG0784	Response regulator, receiver
XCR_RS04500	COG2197	response regulator
XCR_RS04525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_RS04530	COG0583	DNA-binding transcription factor activity
XCR_RS04535	COG3634	alkyl hydroperoxide reductase activity
XCR_RS04545	COG2890	protein-(glutamine-N5) methyltransferase activity
XCR_RS04565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCR_RS04565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCR_RS04570	COG0778	Nitroreductase
XCR_RS04620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCR_RS04625	COG1404	Belongs to the peptidase S8 family
XCR_RS04630	COG1404	Belongs to the peptidase S8 family
XCR_RS04635	COG1404	Belongs to the peptidase S8 family
XCR_RS04640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCR_RS04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_RS04690	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCR_RS04730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCR_RS04740	COG0193	aminoacyl-tRNA hydrolase activity
XCR_RS04745	COG0012	GTP binding
XCR_RS04765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCR_RS04775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XCR_RS04780	COG0250	Participates in transcription elongation, termination and antitermination
XCR_RS04785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCR_RS04830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCR_RS04855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCR_RS04930	COG1841	ribosomal large subunit assembly
XCR_RS04935	COG0200	Binds to the 23S rRNA
XCR_RS04940	COG0201	protein transport
XCR_RS04975	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCR_RS04985	COG0154	amidase activity
XCR_RS04995	COG1217	gtp-binding protein TYPA
XCR_RS05000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCR_RS05010	COG0625	glutathione transferase activity
XCR_RS05030	COG1902	pentaerythritol trinitrate reductase activity
XCR_RS05030	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCR_RS05040	COG2885	chlorophyll binding
XCR_RS05065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCR_RS05070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCR_RS05075	COG4208	sulfate ABC transporter
XCR_RS05080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCR_RS05105	COG0406	alpha-ribazole phosphatase activity
XCR_RS05120	COG0285	dihydrofolate synthase activity
XCR_RS05140	COG2833	Protein of unknown function (DUF455)
XCR_RS05145	COG3291	Pkd domain containing protein
XCR_RS05155	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCR_RS05160	COG0671	phosphoesterase, PA-phosphatase related
XCR_RS05165	COG0438	transferase activity, transferring glycosyl groups
XCR_RS05175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCR_RS05185	COG0745	RESPONSE REGULATOR receiver
XCR_RS05190	COG4783	chaperone-mediated protein folding
XCR_RS05210	COG0473	3-isopropylmalate dehydrogenase activity
XCR_RS05285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCR_RS05315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCR_RS05320	COG0631	protein serine/threonine phosphatase activity
XCR_RS05335	COG0859	PFAM glycosyl transferase family 9
XCR_RS05345	COG1234	tRNA 3'-trailer cleavage
XCR_RS05365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCR_RS05370	COG0314	molybdopterin synthase activity
XCR_RS05395	COG0537	adenosine 5'-monophosphoramidase activity
XCR_RS05415	COG0714	Associated with various cellular activities
XCR_RS05445	COG1399	metal-binding, possibly nucleic acid-binding protein
XCR_RS05455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_RS05460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCR_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS05480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCR_RS05485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCR_RS05515	COG3829	transcription factor binding
XCR_RS05535	COG3609	addiction module antidote protein, CC2985 family
XCR_RS05560	COG2373	Large extracellular alpha-helical protein
XCR_RS05585	COG4953	penicillin-binding protein 1C
XCR_RS05595	COG0678	peroxiredoxin activity
XCR_RS05615	COG0330	HflC and HflK could
XCR_RS05620	COG0330	HflC and HflK could
XCR_RS05635	COG0308	aminopeptidase N
XCR_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS05660	COG1309	transcriptional regulator
XCR_RS05670	COG3039	Transposase
XCR_RS05725	COG4804	nuclease activity
XCR_RS05730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCR_RS05755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCR_RS05770	COG3387	PFAM Glycoside hydrolase 15-related
XCR_RS05775	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS05785	COG3537	Alpha-1,2-mannosidase
XCR_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS05830	COG1064	alcohol dehydrogenase
XCR_RS05835	COG1309	transcriptional regulator
XCR_RS05850	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS05855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_RS05860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCR_RS05865	COG2080	2 iron, 2 sulfur cluster binding
XCR_RS05890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCR_RS05915	COG1297	OPT oligopeptide transporter protein
XCR_RS05925	COG0823	Involved in the tonB-independent uptake of proteins
XCR_RS05925	COG1506	peptidase
XCR_RS05940	COG2207	Transcriptional regulator
XCR_RS05940	COG1917	Cupin 2, conserved barrel domain protein
XCR_RS05945	COG0753	catalase activity
XCR_RS05950	COG0656	L-ascorbic acid biosynthetic process
XCR_RS05975	COG2814	Major facilitator Superfamily
XCR_RS06010	COG0745	RESPONSE REGULATOR receiver
XCR_RS06015	COG5002	protein histidine kinase activity
XCR_RS06030	COG2894	cell division
XCR_RS06045	COG4585	Histidine kinase
XCR_RS06050	COG2197	response regulator
XCR_RS06080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCR_RS06145	COG1595	DNA-templated transcription, initiation
XCR_RS06155	COG1946	Acyl-CoA thioesterase
XCR_RS06160	COG1024	Enoyl-CoA hydratase
XCR_RS06165	COG0824	Thioesterase
XCR_RS06170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCR_RS06200	COG0196	riboflavin kinase activity
XCR_RS06230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCR_RS06235	COG1845	cytochrome c oxidase, subunit III
XCR_RS06240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCR_RS06255	COG3152	Membrane
XCR_RS06265	COG2207	Transcriptional regulator
XCR_RS06280	COG1902	pentaerythritol trinitrate reductase activity
XCR_RS06285	COG1366	Belongs to the anti-sigma-factor antagonist family
XCR_RS06290	COG1366	Belongs to the anti-sigma-factor antagonist family
XCR_RS06295	COG2172	sigma factor antagonist activity
XCR_RS06325	COG4771	TonB-dependent receptor
XCR_RS06335	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCR_RS06340	COG2205	protein histidine kinase activity
XCR_RS06350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCR_RS06355	COG2205	protein histidine kinase activity
XCR_RS06355	COG3437	response regulator, receiver
XCR_RS06355	COG3850	Histidine kinase
XCR_RS06355	COG4999	Histidine kinase
XCR_RS06360	COG0784	Response regulator, receiver
XCR_RS06360	COG4191	Histidine kinase
XCR_RS06385	COG3534	alpha-L-arabinofuranosidase
XCR_RS06395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCR_RS06400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCR_RS06415	COG2070	2-Nitropropane dioxygenase
XCR_RS06445	COG0534	Mate efflux family protein
XCR_RS06465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCR_RS06485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCR_RS06490	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS06495	COG0436	Aminotransferase
XCR_RS06500	COG1309	transcriptional regulator
XCR_RS06525	COG3039	Transposase
XCR_RS06555	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_RS06615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCR_RS06705	COG3039	Transposase
XCR_RS06710	COG3039	Transposase
XCR_RS06735	COG3250	beta-galactosidase activity
XCR_RS06740	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCR_RS06750	COG1396	sequence-specific DNA binding
XCR_RS06750	COG3800	Transcriptional regulator
XCR_RS06760	COG1960	acyl-CoA dehydrogenase activity
XCR_RS06765	COG1024	Enoyl-CoA hydratase
XCR_RS06800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCR_RS06805	COG0481	GTPase activity
XCR_RS06850	COG2954	triphosphatase activity
XCR_RS06855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCR_RS06860	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XCR_RS06860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_RS06865	COG3046	protein related to deoxyribodipyrimidine photolyase
XCR_RS06875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCR_RS06880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCR_RS06885	COG1278	Cold shock
XCR_RS06890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_RS06900	COG1201	RNA secondary structure unwinding
XCR_RS06905	COG1793	dna ligase
XCR_RS06915	COG1793	dna ligase
XCR_RS06915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCR_RS06945	COG0183	Belongs to the thiolase family
XCR_RS06965	COG1451	nucleotide metabolic process
XCR_RS06970	COG5487	UPF0391 membrane protein
XCR_RS06980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCR_RS07015	COG1047	Peptidyl-prolyl cis-trans
XCR_RS07025	COG2824	Alkylphosphonate utilization operon protein PhnA
XCR_RS07050	COG1902	pentaerythritol trinitrate reductase activity
XCR_RS07055	COG2814	Major facilitator Superfamily
XCR_RS07090	COG0392	lysyltransferase activity
XCR_RS07090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCR_RS07100	COG0251	oxidation-reduction process
XCR_RS07105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCR_RS07120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCR_RS07145	COG1595	DNA-templated transcription, initiation
XCR_RS07160	COG2878	Part of a membrane complex involved in electron transport
XCR_RS07185	COG0346	lactoylglutathione lyase activity
XCR_RS07195	COG0833	amino acid
XCR_RS07200	COG2040	homocysteine
XCR_RS07210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCR_RS07230	COG1695	Transcriptional regulator
XCR_RS07250	COG1981	membrane
XCR_RS07305	COG0750	zinc metalloprotease
XCR_RS07315	COG0575	Belongs to the CDS family
XCR_RS07320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCR_RS07330	COG0528	UMP kinase activity
XCR_RS07400	COG1393	Belongs to the ArsC family
XCR_RS07415	COG0367	asparagine synthase
XCR_RS07425	COG4774	siderophore transport
XCR_RS07465	COG1566	PFAM secretion protein HlyD family protein
XCR_RS07470	COG2814	Major facilitator Superfamily
XCR_RS07500	COG3104	oligopeptide transport
XCR_RS07530	COG0339	signal peptide processing
XCR_RS07535	COG0386	Belongs to the glutathione peroxidase family
XCR_RS07595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCR_RS07600	COG0084	hydrolase, TatD family'
XCR_RS07615	COG1960	acyl-CoA dehydrogenase activity
XCR_RS07630	COG0367	asparagine synthase
XCR_RS07640	COG0305	Participates in initiation and elongation during chromosome replication
XCR_RS07645	COG0415	Belongs to the DNA photolyase family
XCR_RS07655	COG0583	DNA-binding transcription factor activity
XCR_RS07665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS07695	COG3706	GGDEF domain
XCR_RS07710	COG2801	Transposase and inactivated derivatives
XCR_RS07715	COG2963	transposase activity
XCR_RS07725	COG1404	Belongs to the peptidase S8 family
XCR_RS07745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_RS07755	COG0497	DNA recombination
XCR_RS07760	COG1420	regulation of RNA biosynthetic process
XCR_RS07765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCR_RS07780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCR_RS07805	COG2274	protein secretion by the type I secretion system
XCR_RS07810	COG0583	DNA-binding transcription factor activity
XCR_RS07815	COG1132	(ABC) transporter
XCR_RS07850	COG2850	peptidyl-arginine hydroxylation
XCR_RS07900	COG1131	(ABC) transporter
XCR_RS07905	COG1725	Transcriptional regulator
XCR_RS07910	COG0386	Belongs to the glutathione peroxidase family
XCR_RS07940	COG1609	Transcriptional regulator
XCR_RS07950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCR_RS07960	COG1410	methionine synthase
XCR_RS07960	COG0646	methionine synthase
XCR_RS07965	COG0646	methionine synthase
XCR_RS07965	COG1410	methionine synthase
XCR_RS07970	COG2226	methyltransferase
XCR_RS07975	COG1960	acyl-CoA dehydrogenase activity
XCR_RS07990	COG0557	exoribonuclease II activity
XCR_RS08000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCR_RS08020	COG0704	Plays a role in the regulation of phosphate uptake
XCR_RS08030	COG0581	inorganic phosphate transmembrane transporter activity
XCR_RS08035	COG0573	inorganic phosphate transmembrane transporter activity
XCR_RS08040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCR_RS08065	COG0659	secondary active sulfate transmembrane transporter activity
XCR_RS08070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCR_RS08080	COG1024	Enoyl-CoA hydratase
XCR_RS08090	COG0494	nUDIX hydrolase
XCR_RS08125	COG2264	protein methyltransferase activity
XCR_RS08130	COG0488	(ABC) transporter
XCR_RS08150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCR_RS08165	COG2925	Exonuclease
XCR_RS08170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_RS08175	COG3844	kynureninase activity
XCR_RS08190	COG0288	reversible hydration of carbon dioxide
XCR_RS08220	COG0316	Belongs to the HesB IscA family
XCR_RS08255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCR_RS08265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCR_RS08285	COG4993	Dehydrogenase
XCR_RS08295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCR_RS08350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCR_RS08360	COG0077	Prephenate dehydratase
XCR_RS08360	COG1605	Chorismate mutase
XCR_RS08370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XCR_RS08385	COG0583	DNA-binding transcription factor activity
XCR_RS08460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCR_RS08465	COG4191	Histidine kinase
XCR_RS08465	COG0784	Response regulator, receiver
XCR_RS08480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_RS08500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCR_RS08535	COG3038	cytochrome b561
XCR_RS08550	COG2244	polysaccharide biosynthetic process
XCR_RS08580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCR_RS08585	COG0438	transferase activity, transferring glycosyl groups
XCR_RS08590	COG0438	transferase activity, transferring glycosyl groups
XCR_RS08610	COG1132	(ABC) transporter
XCR_RS08615	COG0477	Major facilitator Superfamily
XCR_RS08620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCR_RS08635	COG1253	flavin adenine dinucleotide binding
XCR_RS08660	COG2134	cdp-diacylglycerol pyrophosphatase
XCR_RS08715	COG2840	Smr protein MutS2
XCR_RS08730	COG1238	metal cluster binding
XCR_RS08745	COG1534	Rna-binding protein
XCR_RS08755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCR_RS08760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCR_RS08775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCR_RS08780	COG1546	Belongs to the CinA family
XCR_RS08785	COG4771	TonB-dependent receptor
XCR_RS08800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCR_RS08840	COG1741	Belongs to the pirin family
XCR_RS08845	COG0583	DNA-binding transcription factor activity
XCR_RS08870	COG0352	thiamine-phosphate diphosphorylase activity
XCR_RS08870	COG0351	phosphomethylpyrimidine kinase
XCR_RS08880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCR_RS08885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCR_RS08900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCR_RS08910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCR_RS08915	COG3734	2-keto-3-deoxy-galactonokinase
XCR_RS08930	COG0800	Aldolase
XCR_RS08970	COG1501	Belongs to the glycosyl hydrolase 31 family
XCR_RS08980	COG1070	Carbohydrate kinase
XCR_RS08990	COG0477	Major facilitator Superfamily
XCR_RS09010	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCR_RS09065	COG1472	Belongs to the glycosyl hydrolase 3 family
XCR_RS09075	COG3706	GGDEF domain
XCR_RS09075	COG5001	Diguanylate cyclase
XCR_RS09075	COG4251	negative regulation of phosphorylation
XCR_RS09075	COG2203	Gaf domain
XCR_RS09080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_RS09085	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCR_RS09100	COG0671	phosphoesterase, PA-phosphatase related
XCR_RS09110	COG1794	racemase activity, acting on amino acids and derivatives
XCR_RS09115	COG0697	spore germination
XCR_RS09140	COG1012	belongs to the aldehyde dehydrogenase family
XCR_RS09175	COG2801	Transposase and inactivated derivatives
XCR_RS09180	COG2963	transposase activity
XCR_RS09185	COG3210	domain, Protein
XCR_RS09190	COG2963	transposase activity
XCR_RS09195	COG2801	Transposase and inactivated derivatives
XCR_RS09205	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCR_RS09235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCR_RS09240	COG0124	histidyl-tRNA synthetase
XCR_RS09285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCR_RS09285	COG0140	phosphoribosyl-ATP diphosphatase activity
XCR_RS09315	COG0531	amino acid
XCR_RS09320	COG0531	amino acid
XCR_RS09335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCR_RS09340	COG0277	FAD linked oxidase domain protein
XCR_RS09375	COG1024	Enoyl-CoA hydratase
XCR_RS09400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCR_RS09405	COG2258	MOSC domain
XCR_RS09415	COG0505	Belongs to the CarA family
XCR_RS09425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCR_RS09430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_RS09440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCR_RS09465	COG3279	Response regulator of the LytR AlgR family
XCR_RS09470	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XCR_RS09485	COG2198	Histidine kinase
XCR_RS09485	COG0784	Response regulator, receiver
XCR_RS09485	COG2205	protein histidine kinase activity
XCR_RS09490	COG0784	Response regulator, receiver
XCR_RS09490	COG2205	protein histidine kinase activity
XCR_RS09490	COG2198	Histidine kinase
XCR_RS09495	COG1024	Enoyl-CoA hydratase
XCR_RS09500	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_RS09530	COG2267	carboxylic ester hydrolase activity
XCR_RS09555	COG0840	transmembrane signaling receptor activity
XCR_RS09565	COG0835	chemotaxis
XCR_RS09575	COG0840	transmembrane signaling receptor activity
XCR_RS09580	COG0840	transmembrane signaling receptor activity
XCR_RS09585	COG0840	transmembrane signaling receptor activity
XCR_RS09590	COG0840	transmembrane signaling receptor activity
XCR_RS09595	COG0840	transmembrane signaling receptor activity
XCR_RS09600	COG0840	transmembrane signaling receptor activity
XCR_RS09605	COG0840	transmembrane signaling receptor activity
XCR_RS09615	COG0840	transmembrane signaling receptor activity
XCR_RS09625	COG0745	RESPONSE REGULATOR receiver
XCR_RS09635	COG0835	chemotaxis
XCR_RS09640	COG1192	Involved in chromosome partitioning
XCR_RS09645	COG1360	Flagellar Motor Protein
XCR_RS09650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCR_RS09710	COG2963	transposase activity
XCR_RS09715	COG2801	Transposase and inactivated derivatives
XCR_RS09740	COG0784	Response regulator, receiver
XCR_RS09740	COG2198	Histidine kinase
XCR_RS09740	COG0643	Histidine kinase
XCR_RS09795	COG1684	flagellar biosynthetic protein fliR
XCR_RS09800	COG1987	bacterial-type flagellum assembly
XCR_RS09860	COG1677	Flagellar hook-basal body complex protein FliE
XCR_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS09920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_RS09940	COG2201	protein-glutamate methylesterase activity
XCR_RS09970	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCR_RS09975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCR_RS09980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCR_RS09990	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCR_RS09990	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCR_RS10010	COG4787	bacterial-type flagellum-dependent cell motility
XCR_RS10020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCR_RS10025	COG1558	bacterial-type flagellum-dependent cell motility
XCR_RS10035	COG0784	Response regulator, receiver
XCR_RS10035	COG0835	chemotaxis
XCR_RS10055	COG4191	Histidine kinase
XCR_RS10090	COG2915	High frequency lysogenization protein hflD homolog
XCR_RS10110	COG0542	response to heat
XCR_RS10130	COG0492	ferredoxin-NADP+ reductase activity
XCR_RS10135	COG1674	ftsk spoiiie
XCR_RS10150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCR_RS10155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCR_RS10160	COG0183	Belongs to the thiolase family
XCR_RS10165	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCR_RS10165	COG1024	Enoyl-CoA hydratase
XCR_RS10190	COG1426	Protein conserved in bacteria
XCR_RS10200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_RS10215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCR_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS10235	COG2124	cytochrome p450
XCR_RS10260	COG0708	Exodeoxyribonuclease III
XCR_RS10270	COG0303	'Molybdopterin
XCR_RS10275	COG0746	molybdenum cofactor guanylyltransferase activity
XCR_RS10285	COG1648	precorrin-2 dehydrogenase activity
XCR_RS10285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCR_RS10295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCR_RS10300	COG2223	nitrite transmembrane transporter activity
XCR_RS10305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCR_RS10315	COG0243	molybdopterin cofactor binding
XCR_RS10335	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCR_RS10345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCR_RS10355	COG0579	oxidoreductase
XCR_RS10370	COG3685	Protein conserved in bacteria
XCR_RS10375	COG2201	protein-glutamate methylesterase activity
XCR_RS10385	COG5001	Diguanylate cyclase
XCR_RS10445	COG3590	peptidase
XCR_RS10460	COG1999	signal sequence binding
XCR_RS10475	COG1733	regulation of RNA biosynthetic process
XCR_RS10500	COG1238	metal cluster binding
XCR_RS10510	COG0840	transmembrane signaling receptor activity
XCR_RS10540	COG4191	Histidine kinase
XCR_RS10540	COG0784	Response regulator, receiver
XCR_RS10550	COG3459	Glycosyltransferase 36 associated
XCR_RS10635	COG0428	transporter
XCR_RS10645	COG1530	ribonuclease E activity
XCR_RS10680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCR_RS10710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCR_RS10725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCR_RS10750	COG0811	peptide transport
XCR_RS10770	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCR_RS10785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCR_RS10795	COG1053	succinate dehydrogenase
XCR_RS10800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCR_RS10810	COG0354	folic acid binding
XCR_RS10820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCR_RS10830	COG0363	glucosamine-6-phosphate deaminase activity
XCR_RS10835	COG0129	dihydroxy-acid dehydratase activity
XCR_RS10840	COG0800	Aldolase
XCR_RS10905	COG5001	Diguanylate cyclase
XCR_RS10910	COG2183	response to ionizing radiation
XCR_RS10935	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCR_RS10945	COG1183	phosphatidylcholine synthase activity
XCR_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS10975	COG0668	transmembrane transport
XCR_RS10995	COG1914	H( )-stimulated, divalent metal cation uptake system
XCR_RS11010	COG2814	Major facilitator Superfamily
XCR_RS11025	COG1335	isochorismatase
XCR_RS11040	COG2197	response regulator
XCR_RS11075	COG0475	glutathione-regulated potassium exporter activity
XCR_RS11075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCR_RS11080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCR_RS11095	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCR_RS11110	COG0539	negative regulation of cytoplasmic translation
XCR_RS11130	COG2957	Belongs to the agmatine deiminase family
XCR_RS11135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCR_RS11160	COG0395	ABC-type sugar transport system, permease component
XCR_RS11170	COG2182	Extracellular solute-binding protein
XCR_RS11195	COG2350	Protein conserved in bacteria
XCR_RS11200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCR_RS11205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCR_RS11210	COG1187	pseudouridine synthase activity
XCR_RS11230	COG0436	Aminotransferase
XCR_RS11290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCR_RS11295	COG4988	ABC transporter
XCR_RS11305	COG1294	oxidase, subunit
XCR_RS11365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCR_RS11370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCR_RS11375	COG0137	argininosuccinate synthase activity
XCR_RS11385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCR_RS11400	COG2166	iron-sulfur cluster assembly
XCR_RS11430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCR_RS11450	COG4302	ethanolamine ammonia-lyase activity
XCR_RS11470	COG4677	pectinesterase activity
XCR_RS11495	COG0402	S-adenosylhomocysteine deaminase activity
XCR_RS11510	COG1509	lysine 2,3-aminomutase activity
XCR_RS11515	COG5001	Diguanylate cyclase
XCR_RS11515	COG3300	MHYT domain
XCR_RS11530	COG0483	inositol monophosphate 1-phosphatase activity
XCR_RS11535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCR_RS11550	COG0488	(ABC) transporter
XCR_RS11555	COG0513	Belongs to the DEAD box helicase family
XCR_RS11590	COG4681	YaeQ
XCR_RS11595	COG2081	HI0933 family
XCR_RS11600	COG5001	Diguanylate cyclase
XCR_RS11600	COG3300	MHYT domain
XCR_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS11640	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCR_RS11650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCR_RS11650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCR_RS11655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCR_RS11670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCR_RS11720	COG0835	chemotaxis
XCR_RS11725	COG0840	transmembrane signaling receptor activity
XCR_RS11735	COG1201	RNA secondary structure unwinding
XCR_RS11750	COG2969	positive regulation of protein catabolic process
XCR_RS11755	COG0625	glutathione transferase activity
XCR_RS11760	COG2857	Cytochrome c1
XCR_RS11765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCR_RS11770	COG0723	plastoquinol--plastocyanin reductase activity
XCR_RS11780	COG0741	lytic transglycosylase activity
XCR_RS11800	COG1702	phosphate starvation-inducible protein PhoH
XCR_RS11820	COG4535	Mg2 and Co2 transporter CorC
XCR_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
XCR_RS11845	COG1177	transmembrane transport
XCR_RS11850	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCR_RS11855	COG3842	ATPase activity
XCR_RS11885	COG3039	Transposase
XCR_RS11895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCR_RS11900	COG0174	glutamine synthetase
XCR_RS11905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_RS11920	COG0477	Major facilitator Superfamily
XCR_RS11930	COG0243	molybdopterin cofactor binding
XCR_RS11940	COG2223	nitrite transmembrane transporter activity
XCR_RS11945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCR_RS11955	COG2733	membrane
XCR_RS11960	COG5002	protein histidine kinase activity
XCR_RS11960	COG2205	protein histidine kinase activity
XCR_RS11960	COG0784	Response regulator, receiver
XCR_RS11970	COG0477	Major facilitator Superfamily
XCR_RS11975	COG1335	isochorismatase
XCR_RS11980	COG1609	Transcriptional regulator
XCR_RS11980	COG2207	Transcriptional regulator
XCR_RS11985	COG2902	Dehydrogenase
XCR_RS11995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_RS12000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_RS12005	COG1609	Transcriptional regulator
XCR_RS12010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_RS12010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCR_RS12015	COG1105	Belongs to the carbohydrate kinase PfkB family
XCR_RS12020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCR_RS12020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCR_RS12075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCR_RS12085	COG1862	Preprotein translocase
XCR_RS12105	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCR_RS12135	COG3291	Pkd domain containing protein
XCR_RS12140	COG0405	Gamma-glutamyltransferase
XCR_RS12145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCR_RS12165	COG0742	ribosomal rna small subunit methyltransferase
XCR_RS12170	COG0326	Molecular chaperone. Has ATPase activity
XCR_RS12175	COG3039	Transposase
XCR_RS12180	COG2963	transposase activity
XCR_RS12185	COG2801	Transposase and inactivated derivatives
XCR_RS12195	COG2801	Transposase and inactivated derivatives
XCR_RS12200	COG2963	transposase activity
XCR_RS12215	COG4206	TonB-dependent receptor
XCR_RS12225	COG0823	Involved in the tonB-independent uptake of proteins
XCR_RS12225	COG1506	peptidase
XCR_RS12255	COG0531	amino acid
XCR_RS12275	COG0006	proline dipeptidase activity
XCR_RS12285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCR_RS12300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_RS12305	COG3938	Belongs to the proline racemase family
XCR_RS12315	COG0552	protein localization to endoplasmic reticulum
XCR_RS12320	COG1194	a g-specific adenine glycosylase
XCR_RS12335	COG0784	Response regulator, receiver
XCR_RS12335	COG4191	Histidine kinase
XCR_RS12345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCR_RS12365	COG0322	excinuclease ABC activity
XCR_RS12425	COG1960	acyl-CoA dehydrogenase activity
XCR_RS12455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_RS12460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCR_RS12465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_RS12490	COG0438	transferase activity, transferring glycosyl groups
XCR_RS12495	COG2244	polysaccharide biosynthetic process
XCR_RS12500	COG0438	transferase activity, transferring glycosyl groups
XCR_RS12505	COG0438	transferase activity, transferring glycosyl groups
XCR_RS12575	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCR_RS12605	COG1082	Xylose isomerase domain protein TIM barrel
XCR_RS12615	COG3039	Transposase
XCR_RS12625	COG0366	Alpha amylase catalytic
XCR_RS12630	COG2963	transposase activity
XCR_RS12635	COG2801	Transposase and inactivated derivatives
XCR_RS12660	COG2801	Transposase and inactivated derivatives
XCR_RS12665	COG2963	transposase activity
XCR_RS12705	COG3702	type iv secretory pathway
XCR_RS12725	COG2948	multi-organism process
XCR_RS12735	COG3736	Type IV secretory pathway, component VirB8
XCR_RS12750	COG3505	Type IV secretory pathway VirD4
XCR_RS12800	COG4969	Belongs to the N-Me-Phe pilin family
XCR_RS12805	COG1611	Belongs to the LOG family
XCR_RS12815	COG2095	MarC family integral membrane protein
XCR_RS12825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCR_RS12885	COG0195	Participates in both transcription termination and antitermination
XCR_RS12900	COG1007	ATP synthesis coupled electron transport
XCR_RS12920	COG0839	Belongs to the complex I subunit 6 family
XCR_RS12940	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCR_RS12945	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCR_RS12965	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCR_RS12985	COG4221	oxidoreductase activity
XCR_RS12995	COG2963	transposase activity
XCR_RS13000	COG2801	Transposase and inactivated derivatives
XCR_RS13085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCR_RS13105	COG2890	protein-(glutamine-N5) methyltransferase activity
XCR_RS13130	COG0433	COG0433 Predicted ATPase
XCR_RS13140	COG0494	nUDIX hydrolase
XCR_RS13155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_RS13170	COG2801	Transposase and inactivated derivatives
XCR_RS13175	COG2336	PFAM SpoVT AbrB
XCR_RS13215	COG0596	Alpha beta hydrolase
XCR_RS13245	COG0717	Belongs to the dCTP deaminase family
XCR_RS13250	COG0489	protein tyrosine kinase activity
XCR_RS13265	COG3590	peptidase
XCR_RS13270	COG3590	peptidase
XCR_RS13290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_RS13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_RS13300	COG2311	Membrane
XCR_RS13305	COG1047	Peptidyl-prolyl cis-trans
XCR_RS13310	COG0791	NLP P60 protein
XCR_RS13315	COG0791	NLP P60 protein
XCR_RS13330	COG2226	methyltransferase
XCR_RS13335	COG1301	dicarboxylic acid transport
XCR_RS13340	COG1785	Belongs to the alkaline phosphatase family
XCR_RS13355	COG0142	geranyltranstransferase activity
XCR_RS13360	COG4104	PAAR repeat-containing protein
XCR_RS13370	COG0312	modulator of DNA gyrase
XCR_RS13380	COG0312	modulator of DNA gyrase
XCR_RS13390	COG3164	Protein of unknown function
XCR_RS13405	COG2968	Membrane
XCR_RS13435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCR_RS13460	COG3118	belongs to the thioredoxin family
XCR_RS13470	COG2155	Conserved Protein
XCR_RS13515	COG2963	transposase activity
XCR_RS13525	COG1132	(ABC) transporter
XCR_RS13530	COG0475	glutathione-regulated potassium exporter activity
XCR_RS13555	COG1187	pseudouridine synthase activity
XCR_RS13560	COG5002	protein histidine kinase activity
XCR_RS13560	COG5001	Diguanylate cyclase
XCR_RS13660	COG1294	oxidase, subunit
XCR_RS13665	COG1271	oxidase subunit
XCR_RS13675	COG3383	formate dehydrogenase (NAD+) activity
XCR_RS13685	COG1404	Belongs to the peptidase S8 family
XCR_RS13705	COG2814	Major facilitator Superfamily
XCR_RS13710	COG0583	DNA-binding transcription factor activity
XCR_RS13730	COG2207	Transcriptional regulator
XCR_RS13745	COG0667	Aldo Keto reductase
XCR_RS13750	COG1309	transcriptional regulator
XCR_RS13760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_RS13775	COG0735	belongs to the Fur family
XCR_RS13810	COG4452	Inner membrane protein CreD
XCR_RS13815	COG2205	protein histidine kinase activity
XCR_RS13825	COG0745	RESPONSE REGULATOR receiver
XCR_RS13830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCR_RS13840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCR_RS13850	COG2198	Histidine kinase
XCR_RS13850	COG0643	Histidine kinase
XCR_RS13855	COG0840	transmembrane signaling receptor activity
XCR_RS13860	COG0835	chemotaxis
XCR_RS13870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCR_RS13880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS13885	COG3590	peptidase
XCR_RS13905	COG1741	Belongs to the pirin family
XCR_RS13925	COG1741	Belongs to the pirin family
XCR_RS13930	COG1966	Carbon starvation protein
XCR_RS13935	COG2879	small protein
XCR_RS13970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCR_RS13975	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_RS13980	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCR_RS13985	COG2080	2 iron, 2 sulfur cluster binding
XCR_RS13990	COG0604	alcohol dehydrogenase
XCR_RS13995	COG4251	negative regulation of phosphorylation
XCR_RS13995	COG5001	Diguanylate cyclase
XCR_RS13995	COG2203	Gaf domain
XCR_RS13995	COG3706	GGDEF domain
XCR_RS14005	COG1401	restriction endodeoxyribonuclease activity
XCR_RS14015	COG0629	single-stranded DNA binding
XCR_RS14020	COG0142	geranyltranstransferase activity
XCR_RS14045	COG0527	aspartate kinase activity
XCR_RS14050	COG0384	phenazine biosynthesis protein PhzF
XCR_RS14055	COG0384	phenazine biosynthesis protein PhzF
XCR_RS14065	COG1764	response to oxidative stress
XCR_RS14085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCR_RS14090	COG0519	Catalyzes the synthesis of GMP from XMP
XCR_RS14120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCR_RS14155	COG0693	protein deglycase activity
XCR_RS14170	COG0719	Fe-S assembly protein
XCR_RS14175	COG0396	ATPase activity
XCR_RS14180	COG0719	Fe-S assembly protein
XCR_RS14185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCR_RS14195	COG2146	nitrite reductase [NAD(P)H] activity
XCR_RS14200	COG4774	siderophore transport
XCR_RS14245	COG1555	photosystem II stabilization
XCR_RS14250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCR_RS14265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCR_RS14275	COG0628	permease
XCR_RS14300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCR_RS14325	COG0271	Belongs to the BolA IbaG family
XCR_RS14335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCR_RS14350	COG1137	ATPase activity
XCR_RS14365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_RS14385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_RS14390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCR_RS14395	COG2239	Acts as a magnesium transporter
XCR_RS14410	COG1294	oxidase, subunit
XCR_RS14415	COG1271	oxidase subunit
XCR_RS14420	COG1113	amino acid transport
XCR_RS14440	COG2197	response regulator
XCR_RS14445	COG0531	amino acid
XCR_RS14515	COG2814	Major facilitator Superfamily
XCR_RS14520	COG0754	glutathionylspermidine amidase activity
XCR_RS14545	COG1842	Phage shock protein A
XCR_RS14580	COG0477	Major facilitator Superfamily
XCR_RS14600	COG2353	YceI-like domain
XCR_RS14620	COG1760	l-serine dehydratase
XCR_RS14630	COG0460	homoserine dehydrogenase
XCR_RS14630	COG0527	aspartate kinase activity
XCR_RS14635	COG0626	cystathionine gamma-synthase activity
XCR_RS14640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCR_RS14655	COG1272	protein, Hemolysin III
XCR_RS14660	COG2982	Protein involved in outer membrane biogenesis
XCR_RS14665	COG0517	IMP dehydrogenase activity
XCR_RS14665	COG0516	GMP reductase activity
XCR_RS14670	COG0463	Glycosyl transferase, family 2
XCR_RS14680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCR_RS14695	COG1309	transcriptional regulator
XCR_RS14745	COG0330	HflC and HflK could
XCR_RS14755	COG3956	TIGRFAM MazG family protein
XCR_RS14760	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCR_RS14765	COG0494	nUDIX hydrolase
XCR_RS14775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCR_RS14780	COG0837	glucose binding
XCR_RS14795	COG1388	LysM domain
XCR_RS14795	COG3858	chitin binding
XCR_RS14800	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCR_RS14810	COG1472	Belongs to the glycosyl hydrolase 3 family
XCR_RS14820	COG3537	Alpha-1,2-mannosidase
XCR_RS14845	COG1446	asparaginase
XCR_RS14850	COG2304	oxidoreductase activity
XCR_RS14855	COG1595	DNA-templated transcription, initiation
XCR_RS14880	COG0643	Histidine kinase
XCR_RS14880	COG0784	Response regulator, receiver
XCR_RS14880	COG2198	Histidine kinase
XCR_RS14885	COG0840	transmembrane signaling receptor activity
XCR_RS14890	COG0835	chemotaxis
XCR_RS14905	COG0189	ligase activity
XCR_RS14920	COG1397	ADP-ribosylglycohydrolase
XCR_RS14930	COG1199	ATP-dependent helicase activity
XCR_RS14940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCR_RS14945	COG1215	transferase activity, transferring glycosyl groups
XCR_RS14955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCR_RS15000	COG1643	Atp-dependent helicase
XCR_RS15005	COG0783	Belongs to the Dps family
XCR_RS15010	COG0514	ATP-dependent DNA helicase (RecQ)
XCR_RS15030	COG1187	pseudouridine synthase activity
XCR_RS15055	COG0583	DNA-binding transcription factor activity
XCR_RS15105	COG0602	queuosine metabolic process
XCR_RS15115	COG2885	chlorophyll binding
XCR_RS15130	COG0848	biopolymer transport protein
XCR_RS15140	COG0824	Thioesterase
XCR_RS15210	COG0477	Major facilitator Superfamily
XCR_RS15230	COG2755	lipolytic protein G-D-S-L family
XCR_RS15230	COG0657	acetylesterase activity
XCR_RS15250	COG0488	(ABC) transporter
XCR_RS15280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCR_RS15280	COG4651	solute:proton antiporter activity
XCR_RS15310	COG4772	TonB-dependent receptor
XCR_RS15320	COG4264	IucA IucC family
XCR_RS15325	COG2814	Major facilitator Superfamily
XCR_RS15330	COG4264	IucA IucC family
XCR_RS15335	COG0019	diaminopimelate decarboxylase activity
XCR_RS15345	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCR_RS15375	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCR_RS15380	COG1797	cobyrinic acid a,c-diamide synthase activity
XCR_RS15400	COG4206	TonB-dependent receptor
XCR_RS15415	COG0542	response to heat
XCR_RS15420	COG1116	anion transmembrane transporter activity
XCR_RS15465	COG1877	trehalose-phosphatase activity
XCR_RS15470	COG3387	PFAM Glycoside hydrolase 15-related
XCR_RS15490	COG0840	transmembrane signaling receptor activity
XCR_RS15510	COG0564	pseudouridine synthase activity
XCR_RS15515	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_RS15525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCR_RS15525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCR_RS15585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCR_RS15615	COG0745	RESPONSE REGULATOR receiver
XCR_RS15700	COG2003	Belongs to the UPF0758 family
XCR_RS15730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCR_RS15735	COG1061	Type III restriction enzyme res subunit
XCR_RS15740	COG1002	Type II restriction enzyme, methylase subunits
XCR_RS15805	COG3273	potassium ion transport
XCR_RS15805	COG0471	metal ion transport
XCR_RS15835	COG1609	Transcriptional regulator
XCR_RS15840	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_RS15850	COG3250	beta-galactosidase activity
XCR_RS15855	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_RS15865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCR_RS15870	COG1115	amino acid carrier protein
XCR_RS15880	COG0308	aminopeptidase N
XCR_RS15885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_RS15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_RS15895	COG2895	sulfate adenylyltransferase (ATP) activity
XCR_RS15895	COG0529	Catalyzes the synthesis of activated sulfate
XCR_RS15935	COG0784	Response regulator, receiver
XCR_RS15935	COG2205	protein histidine kinase activity
XCR_RS15935	COG2198	Histidine kinase
XCR_RS15965	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCR_RS15970	COG3588	fructose-bisphosphate aldolase
XCR_RS15975	COG0469	pyruvate kinase activity
XCR_RS16005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCR_RS16020	COG3047	cAMP biosynthetic process
XCR_RS16030	COG3453	Protein conserved in bacteria
XCR_RS16030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCR_RS16035	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCR_RS16040	COG4149	molybdate abc transporter
XCR_RS16085	COG1376	ErfK ybiS ycfS ynhG family protein
XCR_RS16090	COG0739	heme binding
XCR_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS16100	COG0583	DNA-binding transcription factor activity
XCR_RS16105	COG4773	Receptor
XCR_RS16110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCR_RS16115	COG1301	dicarboxylic acid transport
XCR_RS16145	COG0714	Associated with various cellular activities
XCR_RS16175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCR_RS16200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCR_RS16210	COG2721	sulfolactate sulfo-lyase activity
XCR_RS16225	COG2271	Major facilitator Superfamily
XCR_RS16240	COG0583	DNA-binding transcription factor activity
XCR_RS16245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCR_RS16260	COG1561	YicC-like family, N-terminal region
XCR_RS16270	COG0346	lactoylglutathione lyase activity
XCR_RS16280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCR_RS16305	COG0006	proline dipeptidase activity
XCR_RS16325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCR_RS16345	COG2912	Transglutaminase-like superfamily
XCR_RS16350	COG1773	rubredoxin
XCR_RS16380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCR_RS16410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCR_RS16415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCR_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS16435	COG0671	phosphoesterase, PA-phosphatase related
XCR_RS16440	COG3781	membrane
XCR_RS16450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCR_RS16475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCR_RS16485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCR_RS16505	COG3710	Transcriptional regulator
XCR_RS16515	COG4946	Tricorn protease homolog
XCR_RS16515	COG1506	peptidase
XCR_RS16515	COG0823	Involved in the tonB-independent uptake of proteins
XCR_RS16520	COG0840	transmembrane signaling receptor activity
XCR_RS16525	COG0405	Gamma-glutamyltransferase
XCR_RS16560	COG2226	methyltransferase
XCR_RS16570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCR_RS16580	COG5001	Diguanylate cyclase
XCR_RS16580	COG3300	MHYT domain
XCR_RS16590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCR_RS16595	COG1538	Outer membrane efflux protein
XCR_RS16600	COG1519	Transferase
XCR_RS16605	COG1560	Kdo2-lipid A biosynthetic process
XCR_RS16645	COG4191	Histidine kinase
XCR_RS16655	COG2197	response regulator
XCR_RS16665	COG0642	Histidine kinase
XCR_RS16680	COG2851	Citrate transporter
XCR_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS16690	COG1609	Transcriptional regulator
XCR_RS16695	COG2211	Major facilitator Superfamily
XCR_RS16725	COG0436	Aminotransferase
XCR_RS16745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCR_RS16765	COG0402	S-adenosylhomocysteine deaminase activity
XCR_RS16805	COG1307	EDD domain protein, DegV family
XCR_RS16815	COG0697	spore germination
XCR_RS16825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCR_RS16850	COG0583	DNA-binding transcription factor activity
XCR_RS16875	COG2205	protein histidine kinase activity
XCR_RS16900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCR_RS16910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCR_RS16950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCR_RS16955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCR_RS16960	COG1609	Transcriptional regulator
XCR_RS16970	COG2188	Transcriptional regulator
XCR_RS16995	COG4795	General secretion pathway protein
XCR_RS17000	COG2165	general secretion pathway protein
XCR_RS17015	COG1459	type II secretion system
XCR_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS17065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCR_RS17070	COG4191	Histidine kinase
XCR_RS17075	COG0784	Response regulator, receiver
XCR_RS17080	COG4251	negative regulation of phosphorylation
XCR_RS17085	COG2823	Periplasmic or secreted lipoprotein
XCR_RS17090	COG0673	inositol 2-dehydrogenase activity
XCR_RS17095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCR_RS17130	COG1056	cytidyltransferase-related domain
XCR_RS17130	COG1051	belongs to the nudix hydrolase family
XCR_RS17180	COG1686	Belongs to the peptidase S11 family
XCR_RS17185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCR_RS17190	COG2951	lytic endotransglycosylase activity
XCR_RS17230	COG0772	Belongs to the SEDS family
XCR_RS17245	COG1792	Involved in formation and maintenance of cell shape
XCR_RS17250	COG1077	Cell shape determining protein MreB Mrl
XCR_RS17255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCR_RS17260	COG3284	Transcriptional regulator
XCR_RS17270	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCR_RS17305	COG0308	aminopeptidase N
XCR_RS17310	COG3300	MHYT domain
XCR_RS17310	COG5001	Diguanylate cyclase
XCR_RS17315	COG2226	methyltransferase
XCR_RS17355	COG2801	Transposase and inactivated derivatives
XCR_RS17360	COG2963	transposase activity
XCR_RS17385	COG2832	Protein of unknown function (DUF454)
XCR_RS17395	COG0436	Aminotransferase
XCR_RS17410	COG1505	serine-type exopeptidase activity
XCR_RS17445	COG3275	phosphorelay sensor kinase activity
XCR_RS17460	COG3273	potassium ion transport
XCR_RS17460	COG0471	metal ion transport
XCR_RS17475	COG3706	GGDEF domain
XCR_RS17480	COG0659	secondary active sulfate transmembrane transporter activity
XCR_RS17485	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_RS17485	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_RS17490	COG0840	transmembrane signaling receptor activity
XCR_RS17495	COG5001	Diguanylate cyclase
XCR_RS17495	COG5002	protein histidine kinase activity
XCR_RS17495	COG3447	MASE1 domain protein
XCR_RS17545	COG1113	amino acid transport
XCR_RS17550	COG4305	rare lipoprotein A
XCR_RS17565	COG0697	spore germination
XCR_RS17595	COG1959	2 iron, 2 sulfur cluster binding
XCR_RS17610	COG0823	Involved in the tonB-independent uptake of proteins
XCR_RS17610	COG1506	peptidase
XCR_RS17620	COG2409	Drug exporters of the RND superfamily
XCR_RS17680	COG0435	Glutathione S-transferase
XCR_RS17705	COG3039	Transposase
XCR_RS17735	COG2963	transposase activity
XCR_RS17740	COG2801	Transposase and inactivated derivatives
XCR_RS17825	COG1802	Transcriptional regulator
XCR_RS17880	COG2353	YceI-like domain
XCR_RS17945	COG3712	iron ion homeostasis
XCR_RS17960	COG3386	PFAM SMP-30 Gluconolaconase
XCR_RS17985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCR_RS17990	COG3550	peptidyl-serine autophosphorylation
XCR_RS18020	COG2356	endonuclease I
XCR_RS18025	COG1324	tolerance protein
XCR_RS18040	COG0511	ligase activity, forming carbon-carbon bonds
XCR_RS18050	COG0439	Biotin carboxylase
XCR_RS18085	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCR_RS18095	COG4589	Belongs to the CDS family
XCR_RS18120	COG2453	phosphatase
XCR_RS18120	COG0671	phosphoesterase, PA-phosphatase related
XCR_RS18125	COG2267	carboxylic ester hydrolase activity
XCR_RS18130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCR_RS18140	COG0151	Belongs to the GarS family
XCR_RS18145	COG1289	transmembrane transporter activity
XCR_RS18150	COG2814	Major facilitator Superfamily
XCR_RS18175	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCR_RS18180	COG2816	NAD+ diphosphatase activity
XCR_RS18285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCR_RS18300	COG0436	Aminotransferase
XCR_RS18370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCR_RS18370	COG2111	Na H antiporter
XCR_RS18375	COG1006	Multisubunit Na H antiporter MnhC subunit
XCR_RS18380	COG0651	ATP synthesis coupled electron transport
XCR_RS18390	COG2212	antiporter activity
XCR_RS18395	COG1320	monovalent cation:proton antiporter activity
XCR_RS18420	COG2852	Protein conserved in bacteria
XCR_RS18440	COG3104	oligopeptide transport
XCR_RS18455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCR_RS18470	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCR_RS18480	COG0513	Belongs to the DEAD box helicase family
XCR_RS18490	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS18495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS18530	COG0702	epimerase
XCR_RS18555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCR_RS18565	COG0297	glycogen (starch) synthase activity
XCR_RS18575	COG2354	Protein conserved in bacteria
XCR_RS18580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCR_RS18590	COG1511	domain protein
XCR_RS18590	COG3264	Mechanosensitive ion channel
XCR_RS18600	COG2801	Transposase and inactivated derivatives
XCR_RS18605	COG2963	transposase activity
XCR_RS18615	COG4206	TonB-dependent receptor
XCR_RS18625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCR_RS18635	COG4774	siderophore transport
XCR_RS18645	COG0582	viral genome integration into host DNA
XCR_RS18660	COG1040	competence protein
XCR_RS18685	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS18710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCR_RS18730	COG0657	acetylesterase activity
XCR_RS18740	COG1414	Transcriptional regulator
XCR_RS18750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCR_RS18755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCR_RS18765	COG3485	protocatechuate 3,4-dioxygenase
XCR_RS18770	COG3485	protocatechuate 3,4-dioxygenase
XCR_RS18780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCR_RS18785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCR_RS18810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCR_RS18865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCR_RS18940	COG0840	transmembrane signaling receptor activity
XCR_RS18950	COG1733	regulation of RNA biosynthetic process
XCR_RS18955	COG0702	epimerase
XCR_RS18985	COG0583	DNA-binding transcription factor activity
XCR_RS18990	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCR_RS19015	COG1902	pentaerythritol trinitrate reductase activity
XCR_RS19035	COG2814	Major facilitator Superfamily
XCR_RS19040	COG0583	DNA-binding transcription factor activity
XCR_RS19050	COG0084	hydrolase, TatD family'
XCR_RS19070	COG2252	PERMEase
XCR_RS19080	COG1957	nucleoside hydrolase
XCR_RS19095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS19100	COG3568	Endonuclease Exonuclease Phosphatase
XCR_RS19125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCR_RS19145	COG2072	flavoprotein involved in K transport
XCR_RS19150	COG2351	hydroxyisourate hydrolase activity
XCR_RS19155	COG4807	Protein conserved in bacteria
XCR_RS19160	COG0840	transmembrane signaling receptor activity
XCR_RS19165	COG1643	Atp-dependent helicase
XCR_RS19175	COG1187	pseudouridine synthase activity
XCR_RS19190	COG2130	NADP-dependent
XCR_RS19195	COG0656	L-ascorbic acid biosynthetic process
XCR_RS19220	COG1764	response to oxidative stress
XCR_RS19225	COG1846	Transcriptional regulator
XCR_RS19235	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCR_RS19245	COG0697	spore germination
XCR_RS19255	COG0523	cobalamin synthesis protein
XCR_RS19310	COG1960	acyl-CoA dehydrogenase activity
XCR_RS19315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCR_RS19320	COG4770	biotin carboxylase activity
XCR_RS19350	COG2224	Isocitrate lyase
XCR_RS19355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCR_RS19360	COG0583	DNA-binding transcription factor activity
XCR_RS19395	COG0681	Belongs to the peptidase S26 family
XCR_RS19400	COG0339	signal peptide processing
XCR_RS19405	COG1446	asparaginase
XCR_RS19425	COG0564	pseudouridine synthase activity
XCR_RS19440	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCR_RS19455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_RS19460	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_RS19465	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCR_RS19470	COG0596	Alpha beta hydrolase
XCR_RS19475	COG3177	Filamentation induced by cAMP protein fic
XCR_RS19480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_RS19495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCR_RS19515	COG2204	response regulator
XCR_RS19520	COG4191	Histidine kinase
XCR_RS19525	COG0028	Belongs to the TPP enzyme family
XCR_RS19545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCR_RS19585	COG0183	Belongs to the thiolase family
XCR_RS19595	COG0346	lactoylglutathione lyase activity
XCR_RS19600	COG2032	superoxide dismutase activity
XCR_RS19605	COG2032	superoxide dismutase activity
XCR_RS19615	COG2204	response regulator
XCR_RS19620	COG3852	Histidine kinase
XCR_RS19625	COG0004	ammonium transporteR
XCR_RS19630	COG0347	Belongs to the P(II) protein family
XCR_RS19635	COG0174	glutamine synthetase
XCR_RS19650	COG1881	PFAM PEBP family protein
XCR_RS19675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS19685	COG0588	phosphoglycerate mutase activity
XCR_RS19690	COG0489	protein tyrosine kinase activity
XCR_RS19720	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCR_RS19725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCR_RS19740	COG1125	glycine betaine transport
XCR_RS19740	COG0517	IMP dehydrogenase activity
XCR_RS19755	COG1119	ATPase activity
XCR_RS19765	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCR_RS19780	COG1522	sequence-specific DNA binding
XCR_RS19785	COG3186	Phenylalanine-4-hydroxylase
XCR_RS19795	COG2755	lipolytic protein G-D-S-L family
XCR_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_RS19815	COG1609	Transcriptional regulator
XCR_RS19820	COG3507	Belongs to the glycosyl hydrolase 43 family
XCR_RS19835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCR_RS19845	COG2755	lipolytic protein G-D-S-L family
XCR_RS19845	COG0657	acetylesterase activity
XCR_RS19855	COG2755	lipolytic protein G-D-S-L family
XCR_RS19890	COG0366	Alpha amylase catalytic
XCR_RS19895	COG0366	Alpha amylase catalytic
XCR_RS19925	COG2801	Transposase and inactivated derivatives
XCR_RS19930	COG2963	transposase activity
XCR_RS19935	COG2801	Transposase and inactivated derivatives
XCR_RS19980	COG3661	Belongs to the glycosyl hydrolase 67 family
XCR_RS19990	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_RS20000	COG1472	Belongs to the glycosyl hydrolase 3 family
XCR_RS20005	COG0246	Mannitol dehydrogenase
XCR_RS20045	COG3386	PFAM SMP-30 Gluconolaconase
XCR_RS20065	COG3250	beta-galactosidase activity
XCR_RS20075	COG3693	PFAM glycoside hydrolase, family 10
XCR_RS20090	COG2211	Major facilitator Superfamily
XCR_RS20100	COG3039	Transposase
XCR_RS20115	COG2963	transposase activity
XCR_RS20120	COG2801	Transposase and inactivated derivatives
XCR_RS20135	COG3039	Transposase
XCR_RS20160	COG2937	Belongs to the GPAT DAPAT family
XCR_RS20195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCR_RS20215	COG0210	DNA helicase
XCR_RS20230	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCR_RS20270	COG3135	benzoate transporter
XCR_RS20290	COG0676	glucose-6-phosphate 1-epimerase activity
XCR_RS20310	COG0730	response to heat
XCR_RS20340	COG0302	gtp cyclohydrolase
XCR_RS20355	COG1566	PFAM secretion protein HlyD family protein
XCR_RS20365	COG1289	transmembrane transporter activity
XCR_RS20370	COG0477	Major facilitator Superfamily
XCR_RS20385	COG4221	oxidoreductase activity
XCR_RS20390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_RS20410	COG1487	ribonuclease activity
XCR_RS20450	COG0564	pseudouridine synthase activity
XCR_RS20460	COG0556	nucleotide-excision repair
XCR_RS20475	COG2963	transposase activity
XCR_RS20480	COG2801	Transposase and inactivated derivatives
XCR_RS20500	COG3093	addiction module antidote protein HigA
XCR_RS20505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XCR_RS20510	COG1074	ATP-dependent DNA helicase activity
XCR_RS20515	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCR_RS20550	COG1127	ABC transporter
XCR_RS20555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCR_RS20560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCR_RS20575	COG2853	Lipoprotein
XCR_RS20585	COG0386	Belongs to the glutathione peroxidase family
XCR_RS20595	COG1322	Protein conserved in bacteria
XCR_RS20600	COG0604	alcohol dehydrogenase
XCR_RS20605	COG0583	DNA-binding transcription factor activity
XCR_RS20620	COG0531	amino acid
XCR_RS20630	COG4206	TonB-dependent receptor
XCR_RS20640	COG3706	GGDEF domain
XCR_RS20645	COG3835	regulator
XCR_RS20650	COG1929	Belongs to the glycerate kinase type-1 family
XCR_RS20655	COG2271	Major facilitator Superfamily
XCR_RS20675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCR_RS20680	COG0861	Integral membrane protein TerC family
XCR_RS20685	COG3039	Transposase
XCR_RS20700	COG0584	glycerophosphoryl diester phosphodiesterase
XCR_RS20710	COG0671	phosphoesterase, PA-phosphatase related
XCR_RS20725	COG0726	polysaccharide deacetylase
XCR_RS20730	COG0706	membrane insertase activity