locus-tag	class	description
AD14011_RS00020	COG0187	DNA topoisomerase II activity
AD14011_RS00030	COG0501	Belongs to the peptidase M48B family
AD14011_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD14011_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AD14011_RS00105	COG0793	Belongs to the peptidase S41A family
AD14011_RS00115	COG4942	peptidase
AD14011_RS00125	COG2234	aminopeptidase activity
AD14011_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AD14011_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AD14011_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AD14011_RS00155	COG1064	alcohol dehydrogenase
AD14011_RS00165	COG0493	'glutamate synthase
AD14011_RS00170	COG0070	glutamate synthase
AD14011_RS00170	COG0067	glutamate synthase
AD14011_RS00170	COG0069	glutamate synthase activity
AD14011_RS00185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AD14011_RS00195	COG1741	Belongs to the pirin family
AD14011_RS00200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AD14011_RS00220	COG0583	DNA-binding transcription factor activity
AD14011_RS00275	COG1205	dead DEAH box helicase
AD14011_RS00275	COG1111	helicase
AD14011_RS00280	COG1272	protein, Hemolysin III
AD14011_RS00300	COG2249	NAD(P)H dehydrogenase (quinone) activity
AD14011_RS00310	COG1733	regulation of RNA biosynthetic process
AD14011_RS00360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AD14011_RS00365	COG3237	CsbD-like
AD14011_RS00415	COG0628	permease
AD14011_RS00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AD14011_RS00435	COG0477	Major facilitator Superfamily
AD14011_RS00475	COG0714	Associated with various cellular activities
AD14011_RS00515	COG4772	TonB-dependent receptor
AD14011_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
AD14011_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD14011_RS00790	COG0366	Alpha amylase catalytic
AD14011_RS00795	COG0366	Alpha amylase catalytic
AD14011_RS00835	COG2755	lipolytic protein G-D-S-L family
AD14011_RS00840	COG2272	Belongs to the type-B carboxylesterase lipase family
AD14011_RS00845	COG0657	acetylesterase activity
AD14011_RS00845	COG2755	lipolytic protein G-D-S-L family
AD14011_RS00855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AD14011_RS00870	COG3507	Belongs to the glycosyl hydrolase 43 family
AD14011_RS00875	COG1609	Transcriptional regulator
AD14011_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS00895	COG2755	lipolytic protein G-D-S-L family
AD14011_RS00905	COG3186	Phenylalanine-4-hydroxylase
AD14011_RS00910	COG1522	sequence-specific DNA binding
AD14011_RS00930	COG1752	Esterase of the alpha-beta hydrolase superfamily
AD14011_RS00940	COG1119	ATPase activity
AD14011_RS00950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AD14011_RS00955	COG1125	glycine betaine transport
AD14011_RS00955	COG0517	IMP dehydrogenase activity
AD14011_RS00970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AD14011_RS00975	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AD14011_RS01005	COG0489	protein tyrosine kinase activity
AD14011_RS01020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD14011_RS01045	COG1881	PFAM PEBP family protein
AD14011_RS01060	COG0174	glutamine synthetase
AD14011_RS01065	COG0347	Belongs to the P(II) protein family
AD14011_RS01070	COG0004	ammonium transporteR
AD14011_RS01075	COG3852	Histidine kinase
AD14011_RS01080	COG2204	response regulator
AD14011_RS01090	COG2032	superoxide dismutase activity
AD14011_RS01095	COG2032	superoxide dismutase activity
AD14011_RS01100	COG0346	lactoylglutathione lyase activity
AD14011_RS01110	COG0183	Belongs to the thiolase family
AD14011_RS01150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AD14011_RS01170	COG0028	Belongs to the TPP enzyme family
AD14011_RS01175	COG4191	Histidine kinase
AD14011_RS01180	COG2204	response regulator
AD14011_RS01200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AD14011_RS01215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AD14011_RS01220	COG3177	Filamentation induced by cAMP protein fic
AD14011_RS01225	COG0596	Alpha beta hydrolase
AD14011_RS01230	COG0727	PFAM Uncharacterised protein family (UPF0153)
AD14011_RS01235	COG0318	PFAM AMP-dependent synthetase and ligase
AD14011_RS01240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD14011_RS01255	COG1181	Belongs to the D-alanine--D-alanine ligase family
AD14011_RS01270	COG0564	pseudouridine synthase activity
AD14011_RS01290	COG1446	asparaginase
AD14011_RS01295	COG0339	signal peptide processing
AD14011_RS01300	COG0681	Belongs to the peptidase S26 family
AD14011_RS01335	COG0583	DNA-binding transcription factor activity
AD14011_RS01340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AD14011_RS01345	COG2224	Isocitrate lyase
AD14011_RS01350	COG3706	GGDEF domain
AD14011_RS01375	COG4770	biotin carboxylase activity
AD14011_RS01380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AD14011_RS01385	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS01440	COG0523	cobalamin synthesis protein
AD14011_RS01450	COG0697	spore germination
AD14011_RS01460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AD14011_RS01470	COG1846	Transcriptional regulator
AD14011_RS01475	COG1764	response to oxidative stress
AD14011_RS01500	COG0656	L-ascorbic acid biosynthetic process
AD14011_RS01505	COG2130	NADP-dependent
AD14011_RS01520	COG1187	pseudouridine synthase activity
AD14011_RS01530	COG1643	Atp-dependent helicase
AD14011_RS01535	COG0840	transmembrane signaling receptor activity
AD14011_RS01540	COG4807	Protein conserved in bacteria
AD14011_RS01545	COG2351	hydroxyisourate hydrolase activity
AD14011_RS01550	COG2072	flavoprotein involved in K transport
AD14011_RS01570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AD14011_RS01595	COG3568	Endonuclease Exonuclease Phosphatase
AD14011_RS01615	COG1957	nucleoside hydrolase
AD14011_RS01625	COG2252	PERMEase
AD14011_RS01645	COG0084	hydrolase, TatD family'
AD14011_RS01655	COG0583	DNA-binding transcription factor activity
AD14011_RS01660	COG2814	Major facilitator Superfamily
AD14011_RS01680	COG1902	pentaerythritol trinitrate reductase activity
AD14011_RS01710	COG0583	DNA-binding transcription factor activity
AD14011_RS01735	COG0702	epimerase
AD14011_RS01740	COG1733	regulation of RNA biosynthetic process
AD14011_RS01750	COG0840	transmembrane signaling receptor activity
AD14011_RS01825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AD14011_RS01885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AD14011_RS01910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AD14011_RS01915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AD14011_RS01925	COG3485	protocatechuate 3,4-dioxygenase
AD14011_RS01930	COG3485	protocatechuate 3,4-dioxygenase
AD14011_RS01935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AD14011_RS01940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AD14011_RS01945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AD14011_RS01955	COG1414	Transcriptional regulator
AD14011_RS01985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AD14011_RS02035	COG1040	competence protein
AD14011_RS02050	COG0582	viral genome integration into host DNA
AD14011_RS02090	COG3264	Mechanosensitive ion channel
AD14011_RS02090	COG1511	domain protein
AD14011_RS02100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AD14011_RS02105	COG2354	Protein conserved in bacteria
AD14011_RS02125	COG0297	glycogen (starch) synthase activity
AD14011_RS02135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AD14011_RS02160	COG0702	epimerase
AD14011_RS02200	COG2085	NADP oxidoreductase coenzyme F420-dependent
AD14011_RS02210	COG0513	Belongs to the DEAD box helicase family
AD14011_RS02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
AD14011_RS02235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AD14011_RS02250	COG3104	oligopeptide transport
AD14011_RS02270	COG2852	Protein conserved in bacteria
AD14011_RS02295	COG1320	monovalent cation:proton antiporter activity
AD14011_RS02300	COG2212	antiporter activity
AD14011_RS02310	COG0651	ATP synthesis coupled electron transport
AD14011_RS02315	COG1006	Multisubunit Na H antiporter MnhC subunit
AD14011_RS02320	COG2111	Na H antiporter
AD14011_RS02320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AD14011_RS02395	COG0436	Aminotransferase
AD14011_RS02410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AD14011_RS02515	COG2816	NAD+ diphosphatase activity
AD14011_RS02520	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AD14011_RS02555	COG2814	Major facilitator Superfamily
AD14011_RS02565	COG1289	transmembrane transporter activity
AD14011_RS02570	COG0151	Belongs to the GarS family
AD14011_RS02585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AD14011_RS02590	COG2267	carboxylic ester hydrolase activity
AD14011_RS02595	COG0671	phosphoesterase, PA-phosphatase related
AD14011_RS02595	COG2453	phosphatase
AD14011_RS02620	COG4589	Belongs to the CDS family
AD14011_RS02625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AD14011_RS02660	COG0439	Biotin carboxylase
AD14011_RS02670	COG0511	ligase activity, forming carbon-carbon bonds
AD14011_RS02685	COG1324	tolerance protein
AD14011_RS02690	COG2356	endonuclease I
AD14011_RS02715	COG3550	peptidyl-serine autophosphorylation
AD14011_RS02725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AD14011_RS02750	COG3386	PFAM SMP-30 Gluconolaconase
AD14011_RS02765	COG3712	iron ion homeostasis
AD14011_RS02840	COG2353	YceI-like domain
AD14011_RS02900	COG1802	Transcriptional regulator
AD14011_RS03050	COG0435	Glutathione S-transferase
AD14011_RS03110	COG2409	Drug exporters of the RND superfamily
AD14011_RS03120	COG0823	Involved in the tonB-independent uptake of proteins
AD14011_RS03120	COG1506	peptidase
AD14011_RS03130	COG3706	GGDEF domain
AD14011_RS03135	COG1959	2 iron, 2 sulfur cluster binding
AD14011_RS03170	COG0697	spore germination
AD14011_RS03185	COG4305	rare lipoprotein A
AD14011_RS03190	COG1113	amino acid transport
AD14011_RS03245	COG5001	Diguanylate cyclase
AD14011_RS03245	COG3447	MASE1 domain protein
AD14011_RS03245	COG5002	protein histidine kinase activity
AD14011_RS03250	COG0840	transmembrane signaling receptor activity
AD14011_RS03255	COG5297	Belongs to the glycosyl hydrolase family 6
AD14011_RS03255	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AD14011_RS03260	COG0659	secondary active sulfate transmembrane transporter activity
AD14011_RS03265	COG3706	GGDEF domain
AD14011_RS03280	COG0471	metal ion transport
AD14011_RS03280	COG3273	potassium ion transport
AD14011_RS03295	COG3275	phosphorelay sensor kinase activity
AD14011_RS03335	COG1505	serine-type exopeptidase activity
AD14011_RS03355	COG2832	Protein of unknown function (DUF454)
AD14011_RS03415	COG2226	methyltransferase
AD14011_RS03420	COG5001	Diguanylate cyclase
AD14011_RS03420	COG3300	MHYT domain
AD14011_RS03425	COG0308	aminopeptidase N
AD14011_RS03460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AD14011_RS03470	COG3284	Transcriptional regulator
AD14011_RS03475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD14011_RS03480	COG1077	Cell shape determining protein MreB Mrl
AD14011_RS03485	COG1792	Involved in formation and maintenance of cell shape
AD14011_RS03500	COG0772	Belongs to the SEDS family
AD14011_RS03520	COG3039	Transposase
AD14011_RS03540	COG2951	lytic endotransglycosylase activity
AD14011_RS03545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AD14011_RS03550	COG1686	Belongs to the peptidase S11 family
AD14011_RS03595	COG1056	cytidyltransferase-related domain
AD14011_RS03595	COG1051	belongs to the nudix hydrolase family
AD14011_RS03630	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AD14011_RS03635	COG0673	inositol 2-dehydrogenase activity
AD14011_RS03640	COG2823	Periplasmic or secreted lipoprotein
AD14011_RS03645	COG4251	negative regulation of phosphorylation
AD14011_RS03650	COG0784	Response regulator, receiver
AD14011_RS03655	COG4191	Histidine kinase
AD14011_RS03660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AD14011_RS03665	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS03710	COG1459	type II secretion system
AD14011_RS03725	COG2165	general secretion pathway protein
AD14011_RS03755	COG2188	Transcriptional regulator
AD14011_RS03765	COG1609	Transcriptional regulator
AD14011_RS03770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AD14011_RS03775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AD14011_RS03825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AD14011_RS03835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AD14011_RS03860	COG2205	protein histidine kinase activity
AD14011_RS03865	COG0745	RESPONSE REGULATOR receiver
AD14011_RS03880	COG0583	DNA-binding transcription factor activity
AD14011_RS03900	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AD14011_RS03910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AD14011_RS03920	COG0697	spore germination
AD14011_RS03930	COG1307	EDD domain protein, DegV family
AD14011_RS03970	COG0402	S-adenosylhomocysteine deaminase activity
AD14011_RS03990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AD14011_RS04010	COG0436	Aminotransferase
AD14011_RS04045	COG2211	Major facilitator Superfamily
AD14011_RS04065	COG1609	Transcriptional regulator
AD14011_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS04075	COG2851	Citrate transporter
AD14011_RS04090	COG0642	Histidine kinase
AD14011_RS04100	COG2197	response regulator
AD14011_RS04110	COG4191	Histidine kinase
AD14011_RS04150	COG1560	Kdo2-lipid A biosynthetic process
AD14011_RS04155	COG1519	Transferase
AD14011_RS04160	COG1538	Outer membrane efflux protein
AD14011_RS04165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AD14011_RS04185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AD14011_RS04195	COG2226	methyltransferase
AD14011_RS04230	COG0405	Gamma-glutamyltransferase
AD14011_RS04235	COG0840	transmembrane signaling receptor activity
AD14011_RS04240	COG0823	Involved in the tonB-independent uptake of proteins
AD14011_RS04240	COG1506	peptidase
AD14011_RS04240	COG4946	Tricorn protease homolog
AD14011_RS04255	COG3710	Transcriptional regulator
AD14011_RS04275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AD14011_RS04285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AD14011_RS04310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AD14011_RS04320	COG3781	membrane
AD14011_RS04325	COG0671	phosphoesterase, PA-phosphatase related
AD14011_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS04345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD14011_RS04350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AD14011_RS04380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AD14011_RS04385	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AD14011_RS04410	COG1773	rubredoxin
AD14011_RS04415	COG2912	Transglutaminase-like superfamily
AD14011_RS04435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AD14011_RS04460	COG0006	proline dipeptidase activity
AD14011_RS04485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AD14011_RS04495	COG0346	lactoylglutathione lyase activity
AD14011_RS04505	COG1561	YicC-like family, N-terminal region
AD14011_RS04520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AD14011_RS04530	COG0583	DNA-binding transcription factor activity
AD14011_RS04545	COG2271	Major facilitator Superfamily
AD14011_RS04560	COG2721	sulfolactate sulfo-lyase activity
AD14011_RS04570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AD14011_RS04600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AD14011_RS04630	COG0714	Associated with various cellular activities
AD14011_RS04650	COG2304	oxidoreductase activity
AD14011_RS04660	COG1301	dicarboxylic acid transport
AD14011_RS04665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AD14011_RS04670	COG0596	Alpha beta hydrolase
AD14011_RS04675	COG4773	Receptor
AD14011_RS04680	COG0583	DNA-binding transcription factor activity
AD14011_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS04690	COG0739	heme binding
AD14011_RS04695	COG1376	ErfK ybiS ycfS ynhG family protein
AD14011_RS04740	COG4149	molybdate abc transporter
AD14011_RS04745	COG0725	ABC transporter, periplasmic molybdate-binding protein
AD14011_RS04755	COG3453	Protein conserved in bacteria
AD14011_RS04755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AD14011_RS04770	COG3047	cAMP biosynthetic process
AD14011_RS04785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AD14011_RS04815	COG0469	pyruvate kinase activity
AD14011_RS04820	COG3588	fructose-bisphosphate aldolase
AD14011_RS04825	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AD14011_RS04855	COG2198	Histidine kinase
AD14011_RS04855	COG0784	Response regulator, receiver
AD14011_RS04855	COG2205	protein histidine kinase activity
AD14011_RS04885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AD14011_RS04895	COG0529	Catalyzes the synthesis of activated sulfate
AD14011_RS04895	COG2895	sulfate adenylyltransferase (ATP) activity
AD14011_RS04900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD14011_RS04905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AD14011_RS04910	COG0308	aminopeptidase N
AD14011_RS04920	COG1115	amino acid carrier protein
AD14011_RS04925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AD14011_RS04930	COG2272	Belongs to the type-B carboxylesterase lipase family
AD14011_RS04935	COG4948	Mandelate Racemase Muconate Lactonizing
AD14011_RS04940	COG3250	beta-galactosidase activity
AD14011_RS04950	COG5297	Belongs to the glycosyl hydrolase family 6
AD14011_RS04955	COG1609	Transcriptional regulator
AD14011_RS04985	COG0471	metal ion transport
AD14011_RS04985	COG3273	potassium ion transport
AD14011_RS05040	COG3209	COG3209 Rhs family protein
AD14011_RS05110	COG2003	Belongs to the UPF0758 family
AD14011_RS05155	COG3039	Transposase
AD14011_RS05160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AD14011_RS05225	COG0745	RESPONSE REGULATOR receiver
AD14011_RS05240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AD14011_RS05325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AD14011_RS05325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AD14011_RS05335	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD14011_RS05340	COG0564	pseudouridine synthase activity
AD14011_RS05360	COG0840	transmembrane signaling receptor activity
AD14011_RS05375	COG3387	PFAM Glycoside hydrolase 15-related
AD14011_RS05380	COG1877	trehalose-phosphatase activity
AD14011_RS05425	COG1116	anion transmembrane transporter activity
AD14011_RS05430	COG0542	response to heat
AD14011_RS05445	COG4206	TonB-dependent receptor
AD14011_RS05465	COG1797	cobyrinic acid a,c-diamide synthase activity
AD14011_RS05470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AD14011_RS05500	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AD14011_RS05510	COG0019	diaminopimelate decarboxylase activity
AD14011_RS05515	COG4264	IucA IucC family
AD14011_RS05520	COG2814	Major facilitator Superfamily
AD14011_RS05525	COG4264	IucA IucC family
AD14011_RS05535	COG4772	TonB-dependent receptor
AD14011_RS05545	COG4651	solute:proton antiporter activity
AD14011_RS05545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AD14011_RS05575	COG0488	(ABC) transporter
AD14011_RS05595	COG0657	acetylesterase activity
AD14011_RS05595	COG2755	lipolytic protein G-D-S-L family
AD14011_RS05615	COG0477	Major facilitator Superfamily
AD14011_RS05685	COG0824	Thioesterase
AD14011_RS05695	COG0848	biopolymer transport protein
AD14011_RS05710	COG2885	chlorophyll binding
AD14011_RS05720	COG0602	queuosine metabolic process
AD14011_RS05765	COG0583	DNA-binding transcription factor activity
AD14011_RS05785	COG0840	transmembrane signaling receptor activity
AD14011_RS05800	COG1187	pseudouridine synthase activity
AD14011_RS05815	COG0514	ATP-dependent DNA helicase (RecQ)
AD14011_RS05820	COG0783	Belongs to the Dps family
AD14011_RS05825	COG1643	Atp-dependent helicase
AD14011_RS05875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AD14011_RS05885	COG1215	transferase activity, transferring glycosyl groups
AD14011_RS05890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AD14011_RS05900	COG1199	ATP-dependent helicase activity
AD14011_RS05915	COG1397	ADP-ribosylglycohydrolase
AD14011_RS05925	COG0189	ligase activity
AD14011_RS05940	COG0835	chemotaxis
AD14011_RS05945	COG0840	transmembrane signaling receptor activity
AD14011_RS05950	COG0643	Histidine kinase
AD14011_RS05950	COG0784	Response regulator, receiver
AD14011_RS05950	COG2198	Histidine kinase
AD14011_RS05975	COG1595	DNA-templated transcription, initiation
AD14011_RS05980	COG2304	oxidoreductase activity
AD14011_RS05985	COG1446	asparaginase
AD14011_RS06015	COG3537	Alpha-1,2-mannosidase
AD14011_RS06025	COG1472	Belongs to the glycosyl hydrolase 3 family
AD14011_RS06035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AD14011_RS06040	COG3858	chitin binding
AD14011_RS06040	COG1388	LysM domain
AD14011_RS06060	COG0837	glucose binding
AD14011_RS06065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AD14011_RS06075	COG0494	nUDIX hydrolase
AD14011_RS06080	COG1218	3'(2'),5'-bisphosphate nucleotidase
AD14011_RS06085	COG3956	TIGRFAM MazG family protein
AD14011_RS06095	COG0330	HflC and HflK could
AD14011_RS06145	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS06155	COG1309	transcriptional regulator
AD14011_RS06170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AD14011_RS06180	COG0463	Glycosyl transferase, family 2
AD14011_RS06185	COG0517	IMP dehydrogenase activity
AD14011_RS06185	COG0516	GMP reductase activity
AD14011_RS06190	COG2982	Protein involved in outer membrane biogenesis
AD14011_RS06195	COG1272	protein, Hemolysin III
AD14011_RS06210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AD14011_RS06215	COG0626	cystathionine gamma-synthase activity
AD14011_RS06220	COG0460	homoserine dehydrogenase
AD14011_RS06220	COG0527	aspartate kinase activity
AD14011_RS06235	COG1760	l-serine dehydratase
AD14011_RS06255	COG2353	YceI-like domain
AD14011_RS06275	COG0477	Major facilitator Superfamily
AD14011_RS06315	COG1842	Phage shock protein A
AD14011_RS06340	COG0754	glutathionylspermidine amidase activity
AD14011_RS06345	COG2814	Major facilitator Superfamily
AD14011_RS06415	COG0531	amino acid
AD14011_RS06420	COG2197	response regulator
AD14011_RS06440	COG1113	amino acid transport
AD14011_RS06445	COG1271	oxidase subunit
AD14011_RS06450	COG1294	oxidase, subunit
AD14011_RS06460	COG2239	Acts as a magnesium transporter
AD14011_RS06465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AD14011_RS06470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD14011_RS06490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD14011_RS06505	COG1137	ATPase activity
AD14011_RS06520	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AD14011_RS06530	COG0271	Belongs to the BolA IbaG family
AD14011_RS06555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AD14011_RS06580	COG0628	permease
AD14011_RS06585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AD14011_RS06590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AD14011_RS06605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AD14011_RS06610	COG1555	photosystem II stabilization
AD14011_RS06655	COG4774	siderophore transport
AD14011_RS06660	COG2146	nitrite reductase [NAD(P)H] activity
AD14011_RS06670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AD14011_RS06675	COG0719	Fe-S assembly protein
AD14011_RS06680	COG0396	ATPase activity
AD14011_RS06685	COG0719	Fe-S assembly protein
AD14011_RS06700	COG0693	protein deglycase activity
AD14011_RS06740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AD14011_RS06770	COG0519	Catalyzes the synthesis of GMP from XMP
AD14011_RS06795	COG1764	response to oxidative stress
AD14011_RS06805	COG0384	phenazine biosynthesis protein PhzF
AD14011_RS06810	COG0384	phenazine biosynthesis protein PhzF
AD14011_RS06815	COG0527	aspartate kinase activity
AD14011_RS06840	COG0142	geranyltranstransferase activity
AD14011_RS06845	COG0629	single-stranded DNA binding
AD14011_RS06855	COG3713	MltA-interacting MipA family protein
AD14011_RS06865	COG0745	RESPONSE REGULATOR receiver
AD14011_RS06870	COG2205	protein histidine kinase activity
AD14011_RS06875	COG5001	Diguanylate cyclase
AD14011_RS06875	COG3706	GGDEF domain
AD14011_RS06875	COG2203	Gaf domain
AD14011_RS06875	COG4251	negative regulation of phosphorylation
AD14011_RS06880	COG0604	alcohol dehydrogenase
AD14011_RS06885	COG2080	2 iron, 2 sulfur cluster binding
AD14011_RS06890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AD14011_RS06895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AD14011_RS06900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AD14011_RS06935	COG2879	small protein
AD14011_RS06940	COG1966	Carbon starvation protein
AD14011_RS06945	COG1741	Belongs to the pirin family
AD14011_RS06965	COG1741	Belongs to the pirin family
AD14011_RS06985	COG3590	peptidase
AD14011_RS06990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD14011_RS07000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AD14011_RS07005	COG2199	diguanylate cyclase activity
AD14011_RS07005	COG2200	EAL domain
AD14011_RS07005	COG2202	Pas domain
AD14011_RS07010	COG0835	chemotaxis
AD14011_RS07015	COG0840	transmembrane signaling receptor activity
AD14011_RS07020	COG2198	Histidine kinase
AD14011_RS07020	COG0643	Histidine kinase
AD14011_RS07030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AD14011_RS07045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AD14011_RS07050	COG0745	RESPONSE REGULATOR receiver
AD14011_RS07060	COG2205	protein histidine kinase activity
AD14011_RS07070	COG4452	Inner membrane protein CreD
AD14011_RS07105	COG0735	belongs to the Fur family
AD14011_RS07120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AD14011_RS07130	COG1309	transcriptional regulator
AD14011_RS07135	COG0667	Aldo Keto reductase
AD14011_RS07150	COG2207	Transcriptional regulator
AD14011_RS07160	COG0583	DNA-binding transcription factor activity
AD14011_RS07165	COG2814	Major facilitator Superfamily
AD14011_RS07185	COG1404	Belongs to the peptidase S8 family
AD14011_RS07195	COG3383	formate dehydrogenase (NAD+) activity
AD14011_RS07205	COG1271	oxidase subunit
AD14011_RS07210	COG1294	oxidase, subunit
AD14011_RS07310	COG5002	protein histidine kinase activity
AD14011_RS07310	COG5001	Diguanylate cyclase
AD14011_RS07315	COG1187	pseudouridine synthase activity
AD14011_RS07340	COG0475	glutathione-regulated potassium exporter activity
AD14011_RS07345	COG1132	(ABC) transporter
AD14011_RS07395	COG2155	Conserved Protein
AD14011_RS07405	COG3118	belongs to the thioredoxin family
AD14011_RS07430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AD14011_RS07460	COG2968	Membrane
AD14011_RS07470	COG1530	ribonuclease E activity
AD14011_RS07475	COG3164	Protein of unknown function
AD14011_RS07485	COG0312	modulator of DNA gyrase
AD14011_RS07495	COG0312	modulator of DNA gyrase
AD14011_RS07505	COG4104	PAAR repeat-containing protein
AD14011_RS07510	COG0142	geranyltranstransferase activity
AD14011_RS07525	COG1785	Belongs to the alkaline phosphatase family
AD14011_RS07530	COG1301	dicarboxylic acid transport
AD14011_RS07550	COG0791	NLP P60 protein
AD14011_RS07555	COG0791	NLP P60 protein
AD14011_RS07560	COG1047	Peptidyl-prolyl cis-trans
AD14011_RS07565	COG2311	Membrane
AD14011_RS07570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AD14011_RS07575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AD14011_RS07595	COG3590	peptidase
AD14011_RS07600	COG3590	peptidase
AD14011_RS07615	COG4206	TonB-dependent receptor
AD14011_RS07620	COG0489	protein tyrosine kinase activity
AD14011_RS07625	COG0717	Belongs to the dCTP deaminase family
AD14011_RS07660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD14011_RS07675	COG0494	nUDIX hydrolase
AD14011_RS07690	COG0433	COG0433 Predicted ATPase
AD14011_RS07715	COG2890	protein-(glutamine-N5) methyltransferase activity
AD14011_RS07730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AD14011_RS07735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AD14011_RS07820	COG4221	oxidoreductase activity
AD14011_RS07840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD14011_RS07860	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AD14011_RS07865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AD14011_RS07885	COG0839	Belongs to the complex I subunit 6 family
AD14011_RS07905	COG1007	ATP synthesis coupled electron transport
AD14011_RS07920	COG0195	Participates in both transcription termination and antitermination
AD14011_RS07980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AD14011_RS07990	COG2095	MarC family integral membrane protein
AD14011_RS08000	COG1611	Belongs to the LOG family
AD14011_RS08065	COG3505	Type IV secretory pathway VirD4
AD14011_RS08085	COG2948	multi-organism process
AD14011_RS08105	COG3702	type iv secretory pathway
AD14011_RS08165	COG3039	Transposase
AD14011_RS08190	COG0366	Alpha amylase catalytic
AD14011_RS08205	COG1082	Xylose isomerase domain protein TIM barrel
AD14011_RS08235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AD14011_RS08305	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS08310	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS08315	COG2244	polysaccharide biosynthetic process
AD14011_RS08320	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS08345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AD14011_RS08355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD14011_RS08385	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS08410	COG0583	DNA-binding transcription factor activity
AD14011_RS08415	COG0667	Aldo Keto reductase
AD14011_RS08425	COG0024	Methionine aminopeptidase
AD14011_RS08440	COG0583	DNA-binding transcription factor activity
AD14011_RS08445	COG0322	excinuclease ABC activity
AD14011_RS08465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AD14011_RS08480	COG0784	Response regulator, receiver
AD14011_RS08480	COG4191	Histidine kinase
AD14011_RS08500	COG0552	protein localization to endoplasmic reticulum
AD14011_RS08510	COG3938	Belongs to the proline racemase family
AD14011_RS08530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AD14011_RS08540	COG0006	proline dipeptidase activity
AD14011_RS08560	COG0531	amino acid
AD14011_RS08590	COG0823	Involved in the tonB-independent uptake of proteins
AD14011_RS08590	COG1506	peptidase
AD14011_RS08620	COG0326	Molecular chaperone. Has ATPase activity
AD14011_RS08625	COG0742	ribosomal rna small subunit methyltransferase
AD14011_RS08645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD14011_RS08650	COG0405	Gamma-glutamyltransferase
AD14011_RS08655	COG3291	Pkd domain containing protein
AD14011_RS08685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AD14011_RS08705	COG1862	Preprotein translocase
AD14011_RS08715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AD14011_RS08745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD14011_RS08745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD14011_RS08750	COG1105	Belongs to the carbohydrate kinase PfkB family
AD14011_RS08755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD14011_RS08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AD14011_RS08760	COG1609	Transcriptional regulator
AD14011_RS08775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AD14011_RS08780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD14011_RS08790	COG2902	Dehydrogenase
AD14011_RS08795	COG2207	Transcriptional regulator
AD14011_RS08795	COG1609	Transcriptional regulator
AD14011_RS08800	COG1335	isochorismatase
AD14011_RS08805	COG0477	Major facilitator Superfamily
AD14011_RS08815	COG5002	protein histidine kinase activity
AD14011_RS08815	COG2205	protein histidine kinase activity
AD14011_RS08815	COG0784	Response regulator, receiver
AD14011_RS08820	COG2733	membrane
AD14011_RS08835	COG2223	nitrite transmembrane transporter activity
AD14011_RS08845	COG0243	molybdopterin cofactor binding
AD14011_RS08855	COG0477	Major facilitator Superfamily
AD14011_RS08860	COG2703	oxygen carrier activity
AD14011_RS08870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AD14011_RS08875	COG0174	glutamine synthetase
AD14011_RS08880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AD14011_RS08915	COG3842	ATPase activity
AD14011_RS08925	COG1176	ABC-type spermidine putrescine transport system, permease component I
AD14011_RS08930	COG1177	transmembrane transport
AD14011_RS08940	COG1012	belongs to the aldehyde dehydrogenase family
AD14011_RS08955	COG4535	Mg2 and Co2 transporter CorC
AD14011_RS08975	COG1702	phosphate starvation-inducible protein PhoH
AD14011_RS08995	COG0741	lytic transglycosylase activity
AD14011_RS09000	COG0723	plastoquinol--plastocyanin reductase activity
AD14011_RS09005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AD14011_RS09010	COG2857	Cytochrome c1
AD14011_RS09015	COG0625	glutathione transferase activity
AD14011_RS09020	COG2969	positive regulation of protein catabolic process
AD14011_RS09035	COG1201	RNA secondary structure unwinding
AD14011_RS09045	COG0840	transmembrane signaling receptor activity
AD14011_RS09050	COG0835	chemotaxis
AD14011_RS09100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AD14011_RS09115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AD14011_RS09120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AD14011_RS09120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AD14011_RS09130	COG0860	N-Acetylmuramoyl-L-alanine amidase
AD14011_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS09170	COG3300	MHYT domain
AD14011_RS09170	COG5001	Diguanylate cyclase
AD14011_RS09175	COG2081	HI0933 family
AD14011_RS09180	COG4681	YaeQ
AD14011_RS09215	COG0513	Belongs to the DEAD box helicase family
AD14011_RS09235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AD14011_RS09240	COG0483	inositol monophosphate 1-phosphatase activity
AD14011_RS09255	COG3300	MHYT domain
AD14011_RS09255	COG5001	Diguanylate cyclase
AD14011_RS09260	COG1509	lysine 2,3-aminomutase activity
AD14011_RS09275	COG0402	S-adenosylhomocysteine deaminase activity
AD14011_RS09335	COG4302	ethanolamine ammonia-lyase activity
AD14011_RS09355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AD14011_RS09380	COG2166	iron-sulfur cluster assembly
AD14011_RS09395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AD14011_RS09405	COG0137	argininosuccinate synthase activity
AD14011_RS09410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AD14011_RS09415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AD14011_RS09475	COG1294	oxidase, subunit
AD14011_RS09485	COG4988	ABC transporter
AD14011_RS09490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AD14011_RS09555	COG0436	Aminotransferase
AD14011_RS09585	COG1187	pseudouridine synthase activity
AD14011_RS09590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AD14011_RS09595	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AD14011_RS09600	COG2350	Protein conserved in bacteria
AD14011_RS09635	COG0395	ABC-type sugar transport system, permease component
AD14011_RS09660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AD14011_RS09665	COG2957	Belongs to the agmatine deiminase family
AD14011_RS09685	COG0539	negative regulation of cytoplasmic translation
AD14011_RS09700	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AD14011_RS09715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AD14011_RS09720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AD14011_RS09720	COG0475	glutathione-regulated potassium exporter activity
AD14011_RS09760	COG2197	response regulator
AD14011_RS09775	COG1335	isochorismatase
AD14011_RS09790	COG2814	Major facilitator Superfamily
AD14011_RS09810	COG1914	H( )-stimulated, divalent metal cation uptake system
AD14011_RS09830	COG0668	transmembrane transport
AD14011_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS09860	COG1183	phosphatidylcholine synthase activity
AD14011_RS09870	COG3243	poly(R)-hydroxyalkanoic acid synthase
AD14011_RS09885	COG0723	plastoquinol--plastocyanin reductase activity
AD14011_RS09885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AD14011_RS09895	COG2183	response to ionizing radiation
AD14011_RS09900	COG5001	Diguanylate cyclase
AD14011_RS09965	COG0800	Aldolase
AD14011_RS09970	COG0129	dihydroxy-acid dehydratase activity
AD14011_RS09975	COG0363	glucosamine-6-phosphate deaminase activity
AD14011_RS09985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AD14011_RS09995	COG0354	folic acid binding
AD14011_RS10010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AD14011_RS10015	COG1053	succinate dehydrogenase
AD14011_RS10025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AD14011_RS10040	COG4591	ABC-type transport system involved in lipoprotein release permease component
AD14011_RS10065	COG0811	peptide transport
AD14011_RS10090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AD14011_RS10105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AD14011_RS10135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AD14011_RS10165	COG1530	ribonuclease E activity
AD14011_RS10175	COG0428	transporter
AD14011_RS10215	COG3781	membrane
AD14011_RS10220	COG0745	RESPONSE REGULATOR receiver
AD14011_RS10220	COG4191	Histidine kinase
AD14011_RS10220	COG2205	protein histidine kinase activity
AD14011_RS10235	COG0667	Aldo Keto reductase
AD14011_RS10240	COG1309	transcriptional regulator
AD14011_RS10245	COG1902	pentaerythritol trinitrate reductase activity
AD14011_RS10265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AD14011_RS10275	COG4206	TonB-dependent receptor
AD14011_RS10285	COG5265	(ABC) transporter
AD14011_RS10325	COG4206	TonB-dependent receptor
AD14011_RS10345	COG0653	protein targeting
AD14011_RS10375	COG2311	Membrane
AD14011_RS10380	COG1309	transcriptional regulator
AD14011_RS10395	COG3279	Response regulator of the LytR AlgR family
AD14011_RS10405	COG3459	Glycosyltransferase 36 associated
AD14011_RS10415	COG0784	Response regulator, receiver
AD14011_RS10415	COG4191	Histidine kinase
AD14011_RS10445	COG3226	Transcriptional regulator
AD14011_RS10450	COG4948	Mandelate Racemase Muconate Lactonizing
AD14011_RS10455	COG1301	dicarboxylic acid transport
AD14011_RS10460	COG0583	DNA-binding transcription factor activity
AD14011_RS10470	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AD14011_RS10480	COG0840	transmembrane signaling receptor activity
AD14011_RS10490	COG1238	metal cluster binding
AD14011_RS10520	COG1733	regulation of RNA biosynthetic process
AD14011_RS10535	COG1999	signal sequence binding
AD14011_RS10550	COG3590	peptidase
AD14011_RS10595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AD14011_RS10615	COG5001	Diguanylate cyclase
AD14011_RS10625	COG2201	protein-glutamate methylesterase activity
AD14011_RS10630	COG3685	Protein conserved in bacteria
AD14011_RS10645	COG0579	oxidoreductase
AD14011_RS10660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AD14011_RS10670	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AD14011_RS10690	COG0243	molybdopterin cofactor binding
AD14011_RS10700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AD14011_RS10705	COG2223	nitrite transmembrane transporter activity
AD14011_RS10710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AD14011_RS10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AD14011_RS10720	COG1648	precorrin-2 dehydrogenase activity
AD14011_RS10730	COG0746	molybdenum cofactor guanylyltransferase activity
AD14011_RS10735	COG0303	'Molybdopterin
AD14011_RS10745	COG0708	Exodeoxyribonuclease III
AD14011_RS10770	COG2124	cytochrome p450
AD14011_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS10790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AD14011_RS10805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD14011_RS10815	COG1426	Protein conserved in bacteria
AD14011_RS10840	COG1250	3-hydroxyacyl-CoA dehydrogenase
AD14011_RS10840	COG1024	Enoyl-CoA hydratase
AD14011_RS10845	COG0183	Belongs to the thiolase family
AD14011_RS10850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AD14011_RS10855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AD14011_RS10870	COG1674	ftsk spoiiie
AD14011_RS10875	COG0492	ferredoxin-NADP+ reductase activity
AD14011_RS10895	COG0542	response to heat
AD14011_RS10915	COG2915	High frequency lysogenization protein hflD homolog
AD14011_RS10945	COG4191	Histidine kinase
AD14011_RS10965	COG0835	chemotaxis
AD14011_RS10965	COG0784	Response regulator, receiver
AD14011_RS10975	COG1558	bacterial-type flagellum-dependent cell motility
AD14011_RS10980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AD14011_RS10990	COG4787	bacterial-type flagellum-dependent cell motility
AD14011_RS11010	COG3951	Flagellar rod assembly protein muramidase FlgJ
AD14011_RS11010	COG1705	Flagellar rod assembly protein muramidase FlgJ
AD14011_RS11020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AD14011_RS11025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AD14011_RS11030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AD14011_RS11060	COG2201	protein-glutamate methylesterase activity
AD14011_RS11080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AD14011_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS11130	COG1677	Flagellar hook-basal body complex protein FliE
AD14011_RS11195	COG1684	flagellar biosynthetic protein fliR
AD14011_RS11200	COG3300	MHYT domain
AD14011_RS11200	COG5001	Diguanylate cyclase
AD14011_RS11250	COG0643	Histidine kinase
AD14011_RS11250	COG0784	Response regulator, receiver
AD14011_RS11250	COG2198	Histidine kinase
AD14011_RS11265	COG0667	Aldo Keto reductase
AD14011_RS11270	COG1309	transcriptional regulator
AD14011_RS11315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AD14011_RS11320	COG1360	Flagellar Motor Protein
AD14011_RS11325	COG1192	Involved in chromosome partitioning
AD14011_RS11330	COG0835	chemotaxis
AD14011_RS11340	COG0745	RESPONSE REGULATOR receiver
AD14011_RS11360	COG0840	transmembrane signaling receptor activity
AD14011_RS11370	COG0840	transmembrane signaling receptor activity
AD14011_RS11375	COG0840	transmembrane signaling receptor activity
AD14011_RS11380	COG0840	transmembrane signaling receptor activity
AD14011_RS11385	COG0840	transmembrane signaling receptor activity
AD14011_RS11405	COG0835	chemotaxis
AD14011_RS11445	COG2267	carboxylic ester hydrolase activity
AD14011_RS11475	COG0318	PFAM AMP-dependent synthetase and ligase
AD14011_RS11480	COG1024	Enoyl-CoA hydratase
AD14011_RS11485	COG2205	protein histidine kinase activity
AD14011_RS11485	COG2198	Histidine kinase
AD14011_RS11485	COG0784	Response regulator, receiver
AD14011_RS11490	COG2198	Histidine kinase
AD14011_RS11490	COG2205	protein histidine kinase activity
AD14011_RS11490	COG0784	Response regulator, receiver
AD14011_RS11510	COG3279	Response regulator of the LytR AlgR family
AD14011_RS11535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AD14011_RS11545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD14011_RS11550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AD14011_RS11560	COG0505	Belongs to the CarA family
AD14011_RS11570	COG2258	MOSC domain
AD14011_RS11575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AD14011_RS11600	COG1024	Enoyl-CoA hydratase
AD14011_RS11635	COG0277	FAD linked oxidase domain protein
AD14011_RS11640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AD14011_RS11655	COG0531	amino acid
AD14011_RS11660	COG0531	amino acid
AD14011_RS11690	COG3039	Transposase
AD14011_RS11695	COG0140	phosphoribosyl-ATP diphosphatase activity
AD14011_RS11695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AD14011_RS11715	COG0131	Imidazoleglycerol-phosphate dehydratase
AD14011_RS11715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AD14011_RS11745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD14011_RS11755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AD14011_RS11800	COG1012	belongs to the aldehyde dehydrogenase family
AD14011_RS11825	COG0697	spore germination
AD14011_RS11830	COG1794	racemase activity, acting on amino acids and derivatives
AD14011_RS11840	COG0671	phosphoesterase, PA-phosphatase related
AD14011_RS11855	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AD14011_RS11860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AD14011_RS11865	COG5001	Diguanylate cyclase
AD14011_RS11865	COG2203	Gaf domain
AD14011_RS11865	COG3706	GGDEF domain
AD14011_RS11865	COG4251	negative regulation of phosphorylation
AD14011_RS11875	COG1472	Belongs to the glycosyl hydrolase 3 family
AD14011_RS11930	COG0860	N-Acetylmuramoyl-L-alanine amidase
AD14011_RS11950	COG0477	Major facilitator Superfamily
AD14011_RS11960	COG1070	Carbohydrate kinase
AD14011_RS11970	COG1501	Belongs to the glycosyl hydrolase 31 family
AD14011_RS12005	COG0800	Aldolase
AD14011_RS12020	COG3734	2-keto-3-deoxy-galactonokinase
AD14011_RS12025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AD14011_RS12035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AD14011_RS12050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AD14011_RS12055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AD14011_RS12065	COG0352	thiamine-phosphate diphosphorylase activity
AD14011_RS12065	COG0351	phosphomethylpyrimidine kinase
AD14011_RS12090	COG0583	DNA-binding transcription factor activity
AD14011_RS12095	COG1741	Belongs to the pirin family
AD14011_RS12130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AD14011_RS12135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AD14011_RS12140	COG4771	TonB-dependent receptor
AD14011_RS12150	COG1546	Belongs to the CinA family
AD14011_RS12155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AD14011_RS12170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AD14011_RS12175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AD14011_RS12185	COG1534	Rna-binding protein
AD14011_RS12200	COG1238	metal cluster binding
AD14011_RS12215	COG2840	Smr protein MutS2
AD14011_RS12275	COG2134	cdp-diacylglycerol pyrophosphatase
AD14011_RS12300	COG1253	flavin adenine dinucleotide binding
AD14011_RS12315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AD14011_RS12320	COG0477	Major facilitator Superfamily
AD14011_RS12325	COG1132	(ABC) transporter
AD14011_RS12345	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS12350	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS12355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AD14011_RS12385	COG2244	polysaccharide biosynthetic process
AD14011_RS12400	COG3038	cytochrome b561
AD14011_RS12435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AD14011_RS12455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AD14011_RS12470	COG4191	Histidine kinase
AD14011_RS12470	COG0784	Response regulator, receiver
AD14011_RS12475	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AD14011_RS12535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AD14011_RS12575	COG0583	DNA-binding transcription factor activity
AD14011_RS12590	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AD14011_RS12600	COG0077	Prephenate dehydratase
AD14011_RS12600	COG1605	Chorismate mutase
AD14011_RS12610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AD14011_RS12665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AD14011_RS12675	COG4993	Dehydrogenase
AD14011_RS12695	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AD14011_RS12705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AD14011_RS12740	COG0316	Belongs to the HesB IscA family
AD14011_RS12770	COG0288	reversible hydration of carbon dioxide
AD14011_RS12795	COG2925	Exonuclease
AD14011_RS12870	COG0494	nUDIX hydrolase
AD14011_RS12880	COG1024	Enoyl-CoA hydratase
AD14011_RS12890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AD14011_RS12895	COG0659	secondary active sulfate transmembrane transporter activity
AD14011_RS12920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AD14011_RS12925	COG0573	inorganic phosphate transmembrane transporter activity
AD14011_RS12930	COG0581	inorganic phosphate transmembrane transporter activity
AD14011_RS12940	COG0704	Plays a role in the regulation of phosphate uptake
AD14011_RS12955	COG3706	GGDEF domain
AD14011_RS12960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AD14011_RS12970	COG0557	exoribonuclease II activity
AD14011_RS12985	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS12990	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS12995	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS13000	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS13005	COG2226	methyltransferase
AD14011_RS13010	COG0646	methionine synthase
AD14011_RS13010	COG1410	methionine synthase
AD14011_RS13015	COG0646	methionine synthase
AD14011_RS13015	COG1410	methionine synthase
AD14011_RS13025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD14011_RS13035	COG1609	Transcriptional regulator
AD14011_RS13065	COG0386	Belongs to the glutathione peroxidase family
AD14011_RS13075	COG1725	Transcriptional regulator
AD14011_RS13080	COG1131	(ABC) transporter
AD14011_RS13110	COG1253	flavin adenine dinucleotide binding
AD14011_RS13130	COG2850	peptidyl-arginine hydroxylation
AD14011_RS13165	COG1132	(ABC) transporter
AD14011_RS13170	COG0583	DNA-binding transcription factor activity
AD14011_RS13175	COG2274	protein secretion by the type I secretion system
AD14011_RS13195	COG0287	Prephenate dehydrogenase
AD14011_RS13195	COG1605	Chorismate mutase
AD14011_RS13200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AD14011_RS13220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AD14011_RS13225	COG1420	regulation of RNA biosynthetic process
AD14011_RS13230	COG0497	DNA recombination
AD14011_RS13240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD14011_RS13260	COG1404	Belongs to the peptidase S8 family
AD14011_RS13280	COG3706	GGDEF domain
AD14011_RS13290	COG3706	GGDEF domain
AD14011_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS13310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD14011_RS13320	COG0583	DNA-binding transcription factor activity
AD14011_RS13340	COG0415	Belongs to the DNA photolyase family
AD14011_RS13345	COG0305	Participates in initiation and elongation during chromosome replication
AD14011_RS13355	COG0367	asparagine synthase
AD14011_RS13370	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS13385	COG0084	hydrolase, TatD family'
AD14011_RS13390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AD14011_RS13450	COG0386	Belongs to the glutathione peroxidase family
AD14011_RS13455	COG0339	signal peptide processing
AD14011_RS13490	COG3104	oligopeptide transport
AD14011_RS13520	COG2814	Major facilitator Superfamily
AD14011_RS13525	COG1566	PFAM secretion protein HlyD family protein
AD14011_RS13565	COG4774	siderophore transport
AD14011_RS13580	COG0367	asparagine synthase
AD14011_RS13595	COG1393	Belongs to the ArsC family
AD14011_RS13665	COG0528	UMP kinase activity
AD14011_RS13675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AD14011_RS13680	COG0575	Belongs to the CDS family
AD14011_RS13690	COG0750	zinc metalloprotease
AD14011_RS13770	COG1695	Transcriptional regulator
AD14011_RS13790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AD14011_RS13800	COG2040	homocysteine
AD14011_RS13805	COG0833	amino acid
AD14011_RS13810	COG0346	lactoylglutathione lyase activity
AD14011_RS13835	COG2878	Part of a membrane complex involved in electron transport
AD14011_RS13850	COG1595	DNA-templated transcription, initiation
AD14011_RS13875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AD14011_RS13890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AD14011_RS13895	COG0251	oxidation-reduction process
AD14011_RS13905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AD14011_RS13905	COG0392	lysyltransferase activity
AD14011_RS13945	COG2814	Major facilitator Superfamily
AD14011_RS13950	COG1902	pentaerythritol trinitrate reductase activity
AD14011_RS13970	COG2824	Alkylphosphonate utilization operon protein PhnA
AD14011_RS13980	COG1047	Peptidyl-prolyl cis-trans
AD14011_RS14025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AD14011_RS14035	COG5487	UPF0391 membrane protein
AD14011_RS14040	COG1451	nucleotide metabolic process
AD14011_RS14060	COG0183	Belongs to the thiolase family
AD14011_RS14100	COG1793	dna ligase
AD14011_RS14105	COG1201	RNA secondary structure unwinding
AD14011_RS14115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD14011_RS14120	COG1278	Cold shock
AD14011_RS14125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AD14011_RS14140	COG3046	protein related to deoxyribodipyrimidine photolyase
AD14011_RS14145	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AD14011_RS14150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AD14011_RS14155	COG2954	triphosphatase activity
AD14011_RS14200	COG0481	GTPase activity
AD14011_RS14205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AD14011_RS14240	COG1024	Enoyl-CoA hydratase
AD14011_RS14245	COG1960	acyl-CoA dehydrogenase activity
AD14011_RS14255	COG1396	sequence-specific DNA binding
AD14011_RS14255	COG3800	Transcriptional regulator
AD14011_RS14265	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AD14011_RS14270	COG3250	beta-galactosidase activity
AD14011_RS14290	COG3039	Transposase
AD14011_RS14315	COG3039	Transposase
AD14011_RS14330	COG2963	transposase activity
AD14011_RS14400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AD14011_RS14455	COG5297	Belongs to the glycosyl hydrolase family 6
AD14011_RS14485	COG3039	Transposase
AD14011_RS14515	COG1309	transcriptional regulator
AD14011_RS14550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AD14011_RS14570	COG0534	Mate efflux family protein
AD14011_RS14600	COG2070	2-Nitropropane dioxygenase
AD14011_RS14615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AD14011_RS14620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AD14011_RS14630	COG3534	alpha-L-arabinofuranosidase
AD14011_RS14655	COG4191	Histidine kinase
AD14011_RS14655	COG0784	Response regulator, receiver
AD14011_RS14660	COG3437	response regulator, receiver
AD14011_RS14660	COG3850	Histidine kinase
AD14011_RS14660	COG4999	Histidine kinase
AD14011_RS14660	COG2205	protein histidine kinase activity
AD14011_RS14665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AD14011_RS14675	COG2205	protein histidine kinase activity
AD14011_RS14680	COG5507	3-demethylubiquinone-9 3-methyltransferase
AD14011_RS14690	COG4771	TonB-dependent receptor
AD14011_RS14710	COG2205	protein histidine kinase activity
AD14011_RS14720	COG2172	sigma factor antagonist activity
AD14011_RS14725	COG1366	Belongs to the anti-sigma-factor antagonist family
AD14011_RS14730	COG1366	Belongs to the anti-sigma-factor antagonist family
AD14011_RS14740	COG0326	Molecular chaperone. Has ATPase activity
AD14011_RS14745	COG2207	Transcriptional regulator
AD14011_RS14760	COG3152	Membrane
AD14011_RS14775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AD14011_RS14780	COG1845	cytochrome c oxidase, subunit III
AD14011_RS14785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AD14011_RS14815	COG0196	riboflavin kinase activity
AD14011_RS14845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AD14011_RS14850	COG0824	Thioesterase
AD14011_RS14855	COG1024	Enoyl-CoA hydratase
AD14011_RS14860	COG1946	Acyl-CoA thioesterase
AD14011_RS14925	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AD14011_RS14945	COG2197	response regulator
AD14011_RS14950	COG4585	Histidine kinase
AD14011_RS14965	COG2894	cell division
AD14011_RS14980	COG5002	protein histidine kinase activity
AD14011_RS14985	COG0745	RESPONSE REGULATOR receiver
AD14011_RS15000	COG2194	sulfuric ester hydrolase activity
AD14011_RS15020	COG2814	Major facilitator Superfamily
AD14011_RS15040	COG0656	L-ascorbic acid biosynthetic process
AD14011_RS15045	COG0753	catalase activity
AD14011_RS15055	COG2207	Transcriptional regulator
AD14011_RS15055	COG1917	Cupin 2, conserved barrel domain protein
AD14011_RS15075	COG0823	Involved in the tonB-independent uptake of proteins
AD14011_RS15075	COG1506	peptidase
AD14011_RS15090	COG1297	OPT oligopeptide transporter protein
AD14011_RS15115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AD14011_RS15145	COG2080	2 iron, 2 sulfur cluster binding
AD14011_RS15150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AD14011_RS15155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AD14011_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS15175	COG1309	transcriptional regulator
AD14011_RS15180	COG1064	alcohol dehydrogenase
AD14011_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS15230	COG3537	Alpha-1,2-mannosidase
AD14011_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS15245	COG3387	PFAM Glycoside hydrolase 15-related
AD14011_RS15260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AD14011_RS15315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AD14011_RS15380	COG0330	HflC and HflK could
AD14011_RS15385	COG0330	HflC and HflK could
AD14011_RS15405	COG0678	peroxiredoxin activity
AD14011_RS15415	COG4953	penicillin-binding protein 1C
AD14011_RS15440	COG2373	Large extracellular alpha-helical protein
AD14011_RS15470	COG3609	addiction module antidote protein, CC2985 family
AD14011_RS15490	COG3829	transcription factor binding
AD14011_RS15520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AD14011_RS15525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AD14011_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS15545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AD14011_RS15550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AD14011_RS15560	COG1399	metal-binding, possibly nucleic acid-binding protein
AD14011_RS15585	COG0714	Associated with various cellular activities
AD14011_RS15605	COG0537	adenosine 5'-monophosphoramidase activity
AD14011_RS15635	COG0314	molybdopterin synthase activity
AD14011_RS15640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AD14011_RS15660	COG1234	tRNA 3'-trailer cleavage
AD14011_RS15670	COG0859	PFAM glycosyl transferase family 9
AD14011_RS15685	COG0631	protein serine/threonine phosphatase activity
AD14011_RS15690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AD14011_RS15715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AD14011_RS15790	COG0473	3-isopropylmalate dehydrogenase activity
AD14011_RS15805	COG4783	chaperone-mediated protein folding
AD14011_RS15810	COG0745	RESPONSE REGULATOR receiver
AD14011_RS15820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AD14011_RS15830	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS15835	COG0671	phosphoesterase, PA-phosphatase related
AD14011_RS15840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AD14011_RS15850	COG3291	Pkd domain containing protein
AD14011_RS15855	COG2833	Protein of unknown function (DUF455)
AD14011_RS15875	COG0285	dihydrofolate synthase activity
AD14011_RS15890	COG0406	alpha-ribazole phosphatase activity
AD14011_RS15915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AD14011_RS15920	COG4208	sulfate ABC transporter
AD14011_RS15925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AD14011_RS15930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AD14011_RS15960	COG0604	alcohol dehydrogenase
AD14011_RS15965	COG1902	pentaerythritol trinitrate reductase activity
AD14011_RS15965	COG0446	pyridine nucleotide-disulphide oxidoreductase
AD14011_RS15985	COG0625	glutathione transferase activity
AD14011_RS15995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AD14011_RS16010	COG0154	amidase activity
AD14011_RS16020	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AD14011_RS16055	COG0201	protein transport
AD14011_RS16060	COG0200	Binds to the 23S rRNA
AD14011_RS16065	COG1841	ribosomal large subunit assembly
AD14011_RS16140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AD14011_RS16165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AD14011_RS16195	COG0222	ribosome binding
AD14011_RS16210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AD14011_RS16215	COG0250	Participates in transcription elongation, termination and antitermination
AD14011_RS16220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AD14011_RS16230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AD14011_RS16250	COG0012	GTP binding
AD14011_RS16255	COG0193	aminoacyl-tRNA hydrolase activity
AD14011_RS16265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AD14011_RS16305	COG0521	Mo-molybdopterin cofactor biosynthetic process
AD14011_RS16325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AD14011_RS16355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AD14011_RS16360	COG1404	Belongs to the peptidase S8 family
AD14011_RS16365	COG1404	Belongs to the peptidase S8 family
AD14011_RS16370	COG1404	Belongs to the peptidase S8 family
AD14011_RS16375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AD14011_RS16435	COG0778	Nitroreductase
AD14011_RS16440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AD14011_RS16440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AD14011_RS16460	COG2890	protein-(glutamine-N5) methyltransferase activity
AD14011_RS16470	COG3634	alkyl hydroperoxide reductase activity
AD14011_RS16475	COG0583	DNA-binding transcription factor activity
AD14011_RS16480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD14011_RS16505	COG2197	response regulator
AD14011_RS16510	COG5002	protein histidine kinase activity
AD14011_RS16510	COG0784	Response regulator, receiver
AD14011_RS16510	COG2205	protein histidine kinase activity
AD14011_RS16540	COG0697	spore germination
AD14011_RS16570	COG3386	PFAM SMP-30 Gluconolaconase
AD14011_RS16590	COG1024	Enoyl-CoA hydratase
AD14011_RS16600	COG0318	PFAM AMP-dependent synthetase and ligase
AD14011_RS16605	COG0583	DNA-binding transcription factor activity
AD14011_RS16610	COG3384	dioxygenase
AD14011_RS16640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD14011_RS16645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD14011_RS16655	COG2096	Adenosyltransferase
AD14011_RS16660	COG0123	including yeast histone deacetylase and acetoin utilization protein
AD14011_RS16690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AD14011_RS16725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AD14011_RS16735	COG0642	Histidine kinase
AD14011_RS16750	COG4181	ATPase activity
AD14011_RS16760	COG2175	clavaminate synthase activity
AD14011_RS16770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AD14011_RS16795	COG4771	TonB-dependent receptor
AD14011_RS16810	COG0667	Aldo Keto reductase
AD14011_RS16815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AD14011_RS16825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AD14011_RS16925	COG0366	Alpha amylase catalytic
AD14011_RS16960	COG0604	alcohol dehydrogenase
AD14011_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS16960	COG3321	synthase
AD14011_RS16975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AD14011_RS16990	COG0494	nUDIX hydrolase
AD14011_RS17010	COG0739	heme binding
AD14011_RS17035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AD14011_RS17040	COG1181	Belongs to the D-alanine--D-alanine ligase family
AD14011_RS17065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AD14011_RS17080	COG3116	cell division
AD14011_RS17085	COG0275	rRNA processing
AD14011_RS17135	COG1988	membrane-bound metal-dependent
AD14011_RS17140	COG0277	FAD linked oxidase domain protein
AD14011_RS17155	COG0745	RESPONSE REGULATOR receiver
AD14011_RS17160	COG2205	protein histidine kinase activity
AD14011_RS17170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AD14011_RS17175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AD14011_RS17190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AD14011_RS17220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AD14011_RS17220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AD14011_RS17245	COG0488	(ABC) transporter
AD14011_RS17250	COG0242	peptide deformylase activity
AD14011_RS17255	COG1393	Belongs to the ArsC family
AD14011_RS17270	COG0457	Tetratricopeptide repeat
AD14011_RS17275	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AD14011_RS17280	COG1215	transferase activity, transferring glycosyl groups
AD14011_RS17285	COG1215	transferase activity, transferring glycosyl groups
AD14011_RS17350	COG2188	Transcriptional regulator
AD14011_RS17360	COG1450	Type ii and iii secretion system protein
AD14011_RS17375	COG3166	PFAM Fimbrial assembly family protein
AD14011_RS17380	COG3156	type II secretion system protein K
AD14011_RS17385	COG4795	General secretion pathway protein
AD14011_RS17390	COG2165	general secretion pathway protein
AD14011_RS17395	COG4970	Tfp pilus assembly protein FimT
AD14011_RS17400	COG2165	general secretion pathway protein
AD14011_RS17405	COG1459	type II secretion system
AD14011_RS17410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AD14011_RS17415	COG1404	Belongs to the peptidase S8 family
AD14011_RS17435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AD14011_RS17435	COG0047	phosphoribosylformylglycinamidine synthase activity
AD14011_RS17440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AD14011_RS17445	COG4974	Belongs to the 'phage' integrase family
AD14011_RS17460	COG0795	lipopolysaccharide-transporting ATPase activity
AD14011_RS17520	COG1183	phosphatidylcholine synthase activity
AD14011_RS17545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AD14011_RS17550	COG1127	ABC transporter
AD14011_RS17555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AD14011_RS17555	COG3218	ABC-type transport auxiliary lipoprotein component
AD14011_RS17595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AD14011_RS17600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AD14011_RS17600	COG0662	Cupin 2, conserved barrel domain protein
AD14011_RS17625	COG2086	electron transfer activity
AD14011_RS17635	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AD14011_RS17635	COG0662	Cupin 2, conserved barrel domain protein
AD14011_RS17640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AD14011_RS17645	COG0463	Glycosyl transferase, family 2
AD14011_RS17665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD14011_RS17670	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AD14011_RS17685	COG0438	transferase activity, transferring glycosyl groups
AD14011_RS17710	COG0626	cystathionine gamma-synthase activity
AD14011_RS17740	COG0625	glutathione transferase activity
AD14011_RS17750	COG0513	Belongs to the DEAD box helicase family
AD14011_RS17755	COG0720	synthase
AD14011_RS17770	COG1956	GAF domain-containing protein
AD14011_RS17810	COG0339	signal peptide processing
AD14011_RS17815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AD14011_RS17825	COG2132	Multicopper oxidase
AD14011_RS17865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AD14011_RS17875	COG1136	(ABC) transporter
AD14011_RS17880	COG0577	efflux transmembrane transporter activity
AD14011_RS17900	COG4191	Histidine kinase
AD14011_RS17965	COG0356	it plays a direct role in the translocation of protons across the membrane
AD14011_RS17980	COG1228	amidohydrolase
AD14011_RS17985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AD14011_RS17995	COG0508	dehydrogenase complex catalyzes the overall conversion of
AD14011_RS18025	COG2011	ABC-type metal ion transport system permease component
AD14011_RS18035	COG0697	spore germination
AD14011_RS18065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD14011_RS18070	COG1187	pseudouridine synthase activity
AD14011_RS18075	COG2813	Specifically methylates the guanine in position
AD14011_RS18095	COG5002	protein histidine kinase activity
AD14011_RS18175	COG0842	Transport permease protein
AD14011_RS18180	COG1131	(ABC) transporter
AD14011_RS18185	COG0025	NhaP-type Na H and K H
AD14011_RS18190	COG3795	YCII-related domain
AD14011_RS18195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AD14011_RS18200	COG1573	uracil-dna glycosylase
AD14011_RS18210	COG3384	dioxygenase
AD14011_RS18215	COG0583	DNA-binding transcription factor activity
AD14011_RS18225	COG0667	Aldo Keto reductase
AD14011_RS18235	COG3590	peptidase
AD14011_RS18250	COG0531	amino acid
AD14011_RS18265	COG2972	Histidine kinase
AD14011_RS18285	COG1335	isochorismatase
AD14011_RS18290	COG3685	Protein conserved in bacteria
AD14011_RS18295	COG3685	Protein conserved in bacteria
AD14011_RS18300	COG3546	catalase activity
AD14011_RS18330	COG2204	response regulator
AD14011_RS18340	COG1271	oxidase subunit
AD14011_RS18345	COG1294	oxidase, subunit
AD14011_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS18365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AD14011_RS18385	COG1132	(ABC) transporter
AD14011_RS18400	COG1063	alcohol dehydrogenase
AD14011_RS18440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AD14011_RS18500	COG0251	oxidation-reduction process
AD14011_RS18520	COG0667	Aldo Keto reductase
AD14011_RS18525	COG0583	DNA-binding transcription factor activity
AD14011_RS18545	COG5001	Diguanylate cyclase
AD14011_RS18545	COG4251	negative regulation of phosphorylation
AD14011_RS18545	COG3706	GGDEF domain
AD14011_RS18545	COG2203	Gaf domain
AD14011_RS18620	COG0582	viral genome integration into host DNA
AD14011_RS18635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AD14011_RS18645	COG1560	Kdo2-lipid A biosynthetic process
AD14011_RS18655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AD14011_RS18690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AD14011_RS18690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AD14011_RS18700	COG0242	peptide deformylase activity
AD14011_RS18705	COG1652	LysM domain
AD14011_RS18710	COG0758	DNA mediated transformation
AD14011_RS18730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AD14011_RS18730	COG1754	DNA topoisomerase type I activity
AD14011_RS18750	COG2203	Gaf domain
AD14011_RS18750	COG3706	GGDEF domain
AD14011_RS18750	COG4251	negative regulation of phosphorylation
AD14011_RS18750	COG5001	Diguanylate cyclase
AD14011_RS18755	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS18765	COG0616	signal peptide processing
AD14011_RS18770	COG0534	Mate efflux family protein
AD14011_RS18785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AD14011_RS18790	COG0625	glutathione transferase activity
AD14011_RS18805	COG1252	NADH dehydrogenase
AD14011_RS18810	COG2860	membrane
AD14011_RS18815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AD14011_RS18825	COG2201	protein-glutamate methylesterase activity
AD14011_RS18830	COG2177	Part of the ABC transporter FtsEX involved in
AD14011_RS18835	COG2884	Cell division ATP-binding protein ftsE
AD14011_RS18845	COG3118	belongs to the thioredoxin family
AD14011_RS18850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AD14011_RS18895	COG1473	amidohydrolase
AD14011_RS18900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD14011_RS18930	COG4941	Belongs to the sigma-70 factor family
AD14011_RS18935	COG5383	Protein conserved in bacteria
AD14011_RS18975	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AD14011_RS18980	COG3023	N-Acetylmuramoyl-L-alanine amidase
AD14011_RS18990	COG4948	Mandelate Racemase Muconate Lactonizing
AD14011_RS19000	COG0531	amino acid
AD14011_RS19015	COG4682	membrane
AD14011_RS19020	COG2133	pyrroloquinoline quinone binding
AD14011_RS19030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AD14011_RS19045	COG1610	YqeY-like protein
AD14011_RS19050	COG1295	ribonuclease BN
AD14011_RS19055	COG0358	DNA primase activity
AD14011_RS19105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AD14011_RS19120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AD14011_RS19135	COG3039	Transposase
AD14011_RS19170	COG0739	heme binding
AD14011_RS19185	COG2223	nitrite transmembrane transporter activity
AD14011_RS19195	COG0708	Exodeoxyribonuclease III
AD14011_RS19210	COG1192	Involved in chromosome partitioning
AD14011_RS19215	COG1475	DNA binding
AD14011_RS19235	COG0463	Glycosyl transferase, family 2
AD14011_RS19260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AD14011_RS19285	COG4221	oxidoreductase activity
AD14011_RS19290	COG2755	lipolytic protein G-D-S-L family
AD14011_RS19290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AD14011_RS19300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AD14011_RS19310	COG1166	arginine decarboxylase activity
AD14011_RS19335	COG2960	long-chain fatty acid transporting porin activity
AD14011_RS19415	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AD14011_RS19445	COG1690	Belongs to the RtcB family
AD14011_RS19490	COG1090	epimerase
AD14011_RS19495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AD14011_RS19530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AD14011_RS19555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD14011_RS19560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AD14011_RS19580	COG2197	response regulator
AD14011_RS19585	COG4585	Histidine kinase
AD14011_RS19600	COG1136	(ABC) transporter
AD14011_RS19625	COG0697	spore germination
AD14011_RS19645	COG0180	Tryptophanyl-tRNA synthetase
AD14011_RS19650	COG3237	CsbD-like
AD14011_RS19750	COG2205	protein histidine kinase activity
AD14011_RS19755	COG0745	RESPONSE REGULATOR receiver
AD14011_RS19765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AD14011_RS19795	COG1199	ATP-dependent helicase activity
AD14011_RS19860	COG0625	glutathione transferase activity
AD14011_RS19895	COG4555	ABC transporter
AD14011_RS19905	COG1476	TRANSCRIPTIONal
AD14011_RS19930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AD14011_RS19935	COG1131	(ABC) transporter
AD14011_RS19940	COG0842	Transport permease protein
AD14011_RS19950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AD14011_RS19960	COG1607	acyl-coa hydrolase
AD14011_RS19985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD14011_RS19990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD14011_RS20000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AD14011_RS20000	COG0045	succinate-CoA ligase (ADP-forming) activity
AD14011_RS20000	COG1042	CoA-binding domain protein
AD14011_RS20010	COG2239	Acts as a magnesium transporter
AD14011_RS20025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AD14011_RS20030	COG3387	PFAM Glycoside hydrolase 15-related
AD14011_RS20050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AD14011_RS20060	COG0463	Glycosyl transferase, family 2
AD14011_RS20070	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS20095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AD14011_RS20110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AD14011_RS20185	COG0210	DNA helicase
AD14011_RS20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD14011_RS20205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AD14011_RS20215	COG2159	amidohydrolase
AD14011_RS20270	COG2091	lysine biosynthetic process via aminoadipic acid
AD14011_RS20320	COG1940	carbohydrate kinase activity
AD14011_RS20345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AD14011_RS20355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AD14011_RS20360	COG3162	membrane
AD14011_RS20410	COG1028	Short-chain dehydrogenase reductase Sdr
AD14011_RS20415	COG0179	Fumarylacetoacetate (FAA) hydrolase
AD14011_RS20420	COG4948	Mandelate Racemase Muconate Lactonizing
AD14011_RS20435	COG3254	rhamnose metabolic process
AD14011_RS20440	COG0738	Major facilitator superfamily
AD14011_RS20445	COG1414	Transcriptional regulator
AD14011_RS20465	COG0784	Response regulator, receiver
AD14011_RS20465	COG2205	protein histidine kinase activity
AD14011_RS20470	COG3459	Glycosyltransferase 36 associated
AD14011_RS20475	COG2211	Major facilitator Superfamily
AD14011_RS20480	COG3265	gluconokinase activity
AD14011_RS20485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD14011_RS20505	COG2911	Protein conserved in bacteria
AD14011_RS20510	COG0729	surface antigen
AD14011_RS20530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AD14011_RS20530	COG0519	Catalyzes the synthesis of GMP from XMP
AD14011_RS20540	COG0805	protein transport
AD14011_RS20560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AD14011_RS20600	COG3661	Belongs to the glycosyl hydrolase 67 family
AD14011_RS20610	COG4948	Mandelate Racemase Muconate Lactonizing
AD14011_RS20620	COG1472	Belongs to the glycosyl hydrolase 3 family
AD14011_RS20625	COG0246	Mannitol dehydrogenase
AD14011_RS20665	COG3386	PFAM SMP-30 Gluconolaconase
AD14011_RS20685	COG3250	beta-galactosidase activity
AD14011_RS20695	COG3693	PFAM glycoside hydrolase, family 10
AD14011_RS20710	COG2211	Major facilitator Superfamily
AD14011_RS20750	COG2937	Belongs to the GPAT DAPAT family
AD14011_RS20785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AD14011_RS20805	COG0210	DNA helicase
AD14011_RS20865	COG3135	benzoate transporter
AD14011_RS20890	COG0676	glucose-6-phosphate 1-epimerase activity
AD14011_RS20910	COG0730	response to heat
AD14011_RS20940	COG0302	gtp cyclohydrolase
AD14011_RS20955	COG1566	PFAM secretion protein HlyD family protein
AD14011_RS20965	COG1289	transmembrane transporter activity
AD14011_RS20970	COG0477	Major facilitator Superfamily
AD14011_RS20980	COG0583	DNA-binding transcription factor activity
AD14011_RS20985	COG4221	oxidoreductase activity
AD14011_RS20990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD14011_RS21065	COG0564	pseudouridine synthase activity
AD14011_RS21110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AD14011_RS21115	COG1074	ATP-dependent DNA helicase activity
AD14011_RS21120	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AD14011_RS21125	COG1127	ABC transporter
AD14011_RS21130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AD14011_RS21135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AD14011_RS21150	COG2853	Lipoprotein
AD14011_RS21160	COG0386	Belongs to the glutathione peroxidase family
AD14011_RS21170	COG1322	Protein conserved in bacteria
AD14011_RS21180	COG0604	alcohol dehydrogenase
AD14011_RS21185	COG0583	DNA-binding transcription factor activity
AD14011_RS21205	COG0531	amino acid
AD14011_RS21215	COG4206	TonB-dependent receptor
AD14011_RS21225	COG3706	GGDEF domain
AD14011_RS21230	COG3835	regulator
AD14011_RS21235	COG1929	Belongs to the glycerate kinase type-1 family
AD14011_RS21240	COG2271	Major facilitator Superfamily
AD14011_RS21265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AD14011_RS21270	COG0861	Integral membrane protein TerC family
AD14011_RS21285	COG0584	glycerophosphoryl diester phosphodiesterase
AD14011_RS21300	COG0671	phosphoesterase, PA-phosphatase related
AD14011_RS21310	COG0726	polysaccharide deacetylase
AD14011_RS21315	COG0706	membrane insertase activity