locus-tag	class	description
AMD22_RS00120	ENOG4108C33	Resolvase
AMD22_RS00150	ENOG4108C33	Resolvase
AMD22_RS00170	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AMD22_RS00340	ENOG4105CMA	conjugation trbi family protein
AMD22_RS00450	ENOG4105XMH	SpoVT AbrB domain protein
AMD22_RS00455	ENOG4108C33	Resolvase
AMD22_RS00485	ENOG4108C33	Resolvase
AMD22_RS00500	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AMD22_RS00505	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AMD22_RS00510	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AMD22_RS00515	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AMD22_RS00525	ENOG4108K0D	peptidase, M48
AMD22_RS00555	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AMD22_RS00565	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AMD22_RS00590	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AMD22_RS00610	ENOG4105CN1	protease
AMD22_RS00615	ENOG41063SB	peptidase
AMD22_RS00625	ENOG4107VAM	peptidase, m28
AMD22_RS00650	ENOG4105DQ4	alcohol dehydrogenase
AMD22_RS00655	ENOG4105BZ8	glutamate synthase
AMD22_RS00660	ENOG4105CBC	glutamate synthase
AMD22_RS00690	ENOG4105EXG	Transcriptional regulator
AMD22_RS00700	ENOG4107Y2G	Glycosyl transferase (Group 1
AMD22_RS00705	ENOG4105D3Q	Sugar transferase
AMD22_RS00710	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AMD22_RS00720	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AMD22_RS00725	ENOG4107RA4	Glycosyl transferase (Group 1
AMD22_RS00745	ENOG4105CAQ	asparagine synthetase
AMD22_RS00760	ENOG4105CMR	udp-glucose 4-epimerase
AMD22_RS00775	ENOG4105BZ1	(ABC) transporter
AMD22_RS00885	ENOG4108I5C	dEAD DEAH box helicase
AMD22_RS00890	ENOG4108UT2	hemolysin iii
AMD22_RS00905	ENOG4107FW0	short-chain dehydrogenase reductase
AMD22_RS00910	ENOG4105CHR	reductase
AMD22_RS00930	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AMD22_RS00990	ENOG41067RQ	csbd family
AMD22_RS01010	ENOG4105D4Y	metalloprotease
AMD22_RS01040	ENOG4105K63	Thioredoxin
AMD22_RS01050	ENOG4105CSH	Transporter
AMD22_RS01090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AMD22_RS01120	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AMD22_RS01125	ENOG4105CGF	Aromatic amino acid aminotransferase
AMD22_RS01130	ENOG4105CHB	tonB-dependent Receptor
AMD22_RS01140	ENOG41082W1	Cupin 2, conserved barrel domain protein
AMD22_RS01145	ENOG4105C26	Dehydrogenase
AMD22_RS01170	ENOG4105DMF	Dehydrogenase
AMD22_RS01185	ENOG4105BZU	Histidine kinase
AMD22_RS01190	ENOG4108S01	response regulator
AMD22_RS01210	ENOG4108M3R	transcriptional activator CadC
AMD22_RS01215	ENOG4105RKW	reductase (By
AMD22_RS01290	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AMD22_RS01295	ENOG4105CG3	alpha amylase, catalytic region
AMD22_RS01300	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AMD22_RS01315	ENOG4105EBR	Carboxylesterase
AMD22_RS01330	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AMD22_RS01340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AMD22_RS01345	ENOG4105DSG	hydrolase family 43
AMD22_RS01350	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS01355	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AMD22_RS01360	ENOG4105CHR	reductase
AMD22_RS01370	ENOG4107TDE	lipolytic protein G-D-S-L family
AMD22_RS01385	ENOG4105MIR	Phenylalanine 4-monooxygenase
AMD22_RS01390	ENOG4108YXU	transcriptional regulator AsnC family
AMD22_RS01395	ENOG4105CNM	Receptor
AMD22_RS01400	ENOG4105D78	K07001 NTE family protein
AMD22_RS01410	ENOG4105DKW	ABC transporter
AMD22_RS01425	ENOG4108IJ8	ABC transporter
AMD22_RS01430	ENOG4105E90	ABC transporter
AMD22_RS01485	ENOG4105D1F	ATP-binding protein
AMD22_RS01490	ENOG4105M4E	phosphohistidine phosphatase, SixA
AMD22_RS01500	ENOG4107RZC	phospholipase d
AMD22_RS01505	ENOG4105KA0	thioesterase Superfamily protein
AMD22_RS01545	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AMD22_RS01550	ENOG4105C5F	glutamine synthetase
AMD22_RS01560	ENOG4105BZU	Histidine kinase
AMD22_RS01565	ENOG4105CUX	Signal transduction histidine kinase
AMD22_RS01570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AMD22_RS01575	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AMD22_RS01580	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AMD22_RS01585	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
AMD22_RS01595	ENOG4105CHU	acetyl-coa acetyltransferase
AMD22_RS01630	ENOG4107YZP	Rhodanese domain protein
AMD22_RS01635	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AMD22_RS01640	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AMD22_RS01650	ENOG4105C7K	acetolactate synthase
AMD22_RS01655	ENOG4108TQ9	Histidine kinase
AMD22_RS01660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AMD22_RS01680	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AMD22_RS01695	ENOG4105E2T	synthase III
AMD22_RS01700	ENOG4107R3N	Filamentation induced by cAMP protein fic
AMD22_RS01705	ENOG4108J2P	Alpha beta hydrolase fold
AMD22_RS01710	ENOG4105PI0	Ferredoxin
AMD22_RS01715	ENOG410680H	amp-dependent synthetase and ligase
AMD22_RS01720	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AMD22_RS01735	ENOG4105CPF	Cell wall formation (By similarity)
AMD22_RS01745	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AMD22_RS01755	ENOG4105DR9	pseudouridine synthase
AMD22_RS01765	ENOG4108YZN	class I peptide chain release factor
AMD22_RS01775	ENOG4105D44	asparaginase
AMD22_RS01780	ENOG4105DGW	oligopeptidase A
AMD22_RS01815	ENOG4107R11	Transcriptional regulator
AMD22_RS01820	ENOG4107QP3	malate synthase g
AMD22_RS01830	ENOG4105BZU	Histidine kinase
AMD22_RS01860	ENOG4107QX3	carboxylase
AMD22_RS01865	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS01920	ENOG4105CKI	cobalamin synthesis protein
AMD22_RS01935	ENOG4108TZV	Membrane
AMD22_RS01945	ENOG4105D6Z	AFG1 family ATPase
AMD22_RS01950	ENOG4105K56	Transcriptional regulator
AMD22_RS01955	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AMD22_RS01985	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AMD22_RS02000	ENOG4108R99	pseudouridine synthase
AMD22_RS02005	ENOG4108KPZ	tonB-dependent Receptor
AMD22_RS02015	ENOG4105CQ7	ATP-dependent helicase
AMD22_RS02025	ENOG4108W15	Protein of unknown function (DUF1456)
AMD22_RS02035	ENOG4105E1J	oxidoreductase
AMD22_RS02055	ENOG4105C5R	Aminotransferase
AMD22_RS02065	ENOG4105EQ2	LysR family Transcriptional regulator
AMD22_RS02070	ENOG4107RTG	Major Facilitator superfamily
AMD22_RS02080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AMD22_RS02090	ENOG4105DU0	nucleoside hydrolase
AMD22_RS02100	ENOG4105C7N	Xanthine uracil vitamin C permease
AMD22_RS02120	ENOG4105ETT	transcriptional Regulator, LysR family
AMD22_RS02125	ENOG4105F8V	Hydrolase, tatD family
AMD22_RS02140	ENOG4106NZI	LysR family Transcriptional regulator
AMD22_RS02145	ENOG4105D94	Major Facilitator Superfamily
AMD22_RS02160	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AMD22_RS02165	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AMD22_RS02185	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AMD22_RS02190	ENOG4105EB3	Histidine kinase
AMD22_RS02195	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AMD22_RS02200	ENOG4105BZS	acriflavin resistance protein
AMD22_RS02205	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AMD22_RS02215	ENOG4105DAE	Methylenetetrahydrofolate reductase
AMD22_RS02220	ENOG4105WPN	DNA integration recombination invertion protein
AMD22_RS02225	ENOG4105DZ2	Transcriptional regulator
AMD22_RS02230	ENOG4108UZX	fmn reductase
AMD22_RS02245	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AMD22_RS02255	ENOG4105ECR	NmrA family
AMD22_RS02300	ENOG4105C01	Dihydroxy-acid dehydratase
AMD22_RS02320	ENOG4108Z0R	Transferase
AMD22_RS02330	ENOG4105D2S	major facilitator superfamily
AMD22_RS02335	ENOG4105CPI	Metal Dependent Phosphohydrolase
AMD22_RS02365	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AMD22_RS02375	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AMD22_RS02380	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AMD22_RS02385	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AMD22_RS02390	ENOG4105E98	transcriptional regulator DeoR family
AMD22_RS02415	ENOG4105CHU	acetyl-coa acetyltransferase
AMD22_RS02430	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AMD22_RS02435	ENOG4105F2Z	3-oxoadipate enol-lactonase
AMD22_RS02440	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AMD22_RS02450	ENOG4107HP6	Transcriptional regulator
AMD22_RS02465	ENOG4105MH3	Protein of unknown function (DUF2490)
AMD22_RS02470	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AMD22_RS02505	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AMD22_RS02510	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AMD22_RS02520	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AMD22_RS02525	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AMD22_RS02530	ENOG41081UC	Inherit from COG: Competence protein
AMD22_RS02535	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AMD22_RS02585	ENOG4105VS8	Flagellar biosynthetic protein fliq
AMD22_RS02605	ENOG4108HR8	type iii secretion
AMD22_RS02625	ENOG4107Y59	type iii secretion
AMD22_RS02640	ENOG4108JIR	Flagellum-specific ATP synthase
AMD22_RS02650	ENOG4108TN6	type iii secretion
AMD22_RS02665	ENOG4105FTC	Lytic transglycosylase catalytic
AMD22_RS02680	ENOG4105EGS	Mechanosensitive ion channel
AMD22_RS02685	ENOG4107RES	phosphoglycerol transferase I
AMD22_RS02695	ENOG4105CKW	Inner membrane protein yedI
AMD22_RS02705	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AMD22_RS02710	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AMD22_RS02715	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AMD22_RS02740	ENOG4105K4T	epimerase
AMD22_RS02745	ENOG4107ZQV	short-chain dehydrogenase reductase
AMD22_RS02780	ENOG4105BZS	acriflavin resistance protein
AMD22_RS02785	ENOG4105CHR	reductase
AMD22_RS02795	ENOG4105C1J	atp-dependent rna helicase
AMD22_RS02810	ENOG4105CPP	Dehydrogenase, E1 component
AMD22_RS02815	ENOG4107RUY	(E1 component), alpha subunit
AMD22_RS02825	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AMD22_RS02830	ENOG4105DUX	Transporter
AMD22_RS02845	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AMD22_RS02850	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AMD22_RS02865	ENOG4105KJM	monovalent cation h antiporter subunit g
AMD22_RS02870	ENOG4105W4C	monovalent cation H antiporter subunit F
AMD22_RS02880	ENOG4107R4Z	monovalent cation h antiporter subunit d
AMD22_RS02885	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AMD22_RS02890	ENOG4105D65	subunit l
AMD22_RS02910	ENOG4105NVB	glycoside hydrolase, family 19
AMD22_RS02930	ENOG4105C8V	SAICAR synthetase
AMD22_RS02935	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AMD22_RS02950	ENOG4105KD7	acetyltransferase
AMD22_RS02955	ENOG4107TE5	Lipid kinase
AMD22_RS02960	ENOG4105CRQ	synthase (Component I)
AMD22_RS02970	ENOG4105DDQ	anthranilate synthase
AMD22_RS02980	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AMD22_RS02985	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AMD22_RS02995	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AMD22_RS03000	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AMD22_RS03010	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AMD22_RS03020	ENOG4108UJD	30S ribosomal protein S9
AMD22_RS03035	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AMD22_RS03045	ENOG4108UQY	Iron-storage protein
AMD22_RS03050	ENOG4105BZU	Histidine kinase
AMD22_RS03075	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AMD22_RS03100	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AMD22_RS03120	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AMD22_RS03135	ENOG4105EM2	membrane
AMD22_RS03145	ENOG4105C12	Phosphoribosylglycinamide synthetase
AMD22_RS03155	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AMD22_RS03160	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AMD22_RS03165	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AMD22_RS03170	ENOG41077RS	Phosphatase
AMD22_RS03195	ENOG4108HPI	phosphatidate Cytidylyltransferase
AMD22_RS03200	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AMD22_RS03225	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AMD22_RS03240	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AMD22_RS03250	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AMD22_RS03255	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AMD22_RS03260	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AMD22_RS03265	ENOG4105VF7	tolerance protein
AMD22_RS03280	ENOG4105VV6	START domain-containing protein
AMD22_RS03290	ENOG4105E1F	short-chain dehydrogenase reductase
AMD22_RS03295	ENOG4108K8S	endonuclease I
AMD22_RS03305	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AMD22_RS03320	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AMD22_RS03345	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AMD22_RS03350	ENOG4105EX9	Membrane
AMD22_RS03370	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AMD22_RS03375	ENOG4108YYC	ycei family
AMD22_RS03405	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AMD22_RS03420	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AMD22_RS03430	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AMD22_RS03440	ENOG4105DRR	Transcriptional regulator, GntR family
AMD22_RS03480	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AMD22_RS03495	ENOG4107GJV	short-chain dehydrogenase reductase
AMD22_RS03510	ENOG4105PDP	Short chain dehydrogenase
AMD22_RS03520	ENOG4105CHF	Glutathione S-transferase
AMD22_RS03545	ENOG4105EYF	MMPL domain protein
AMD22_RS03550	ENOG4105C5Z	peptidase
AMD22_RS03555	ENOG4107QS8	(LipO)protein
AMD22_RS03565	ENOG4105BZU	Histidine kinase
AMD22_RS03590	ENOG4105DFI	Membrane
AMD22_RS03595	ENOG4105F87	Dehydratase
AMD22_RS03625	ENOG4105E53	ec 3.2.1.28
AMD22_RS03665	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS03670	ENOG4106R7G	Glycoside hydrolase family 5
AMD22_RS03675	ENOG4105CHH	sulfate transporter
AMD22_RS03685	ENOG4105BZU	Histidine kinase
AMD22_RS03700	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AMD22_RS03710	ENOG4108HRK	Histidine kinase
AMD22_RS03715	ENOG4108NEV	two component transcriptional regulator, LytTR family
AMD22_RS03720	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AMD22_RS03750	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AMD22_RS03765	ENOG4105WD1	Membrane
AMD22_RS03775	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AMD22_RS03785	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AMD22_RS03790	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AMD22_RS03795	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AMD22_RS03820	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AMD22_RS03825	ENOG4105BZU	Histidine kinase
AMD22_RS03830	ENOG4105CD8	aminopeptidase N
AMD22_RS03850	ENOG4105DZG	Dehydrogenase
AMD22_RS03855	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AMD22_RS03880	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AMD22_RS03885	ENOG4107T4Z	adenosine kinase
AMD22_RS03895	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AMD22_RS03910	ENOG4105CNI	cell division protein FtsW
AMD22_RS03915	ENOG4107WN4	Polygalacturonase
AMD22_RS03920	ENOG4105CVE	Lytic murein transglycosylase
AMD22_RS03925	ENOG4105K6T	rare lipoprotein A
AMD22_RS03935	ENOG4105DZ1	carboxypeptidase
AMD22_RS03950	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AMD22_RS03955	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AMD22_RS03960	ENOG4105CN1	protease
AMD22_RS03970	ENOG4105EGI	Transcriptional regulator
AMD22_RS04015	ENOG4108J5G	6-phosphogluconate dehydrogenase
AMD22_RS04020	ENOG4105D9R	oxidoreductase
AMD22_RS04025	ENOG4105W4M	Transport-associated protein
AMD22_RS04030	ENOG4105BZU	Histidine kinase
AMD22_RS04040	ENOG4105BZU	Histidine kinase
AMD22_RS04050	ENOG4105CHR	reductase
AMD22_RS04090	ENOG4105GVR	general secretion pathway protein D
AMD22_RS04095	ENOG4107QHF	type ii secretion system protein e
AMD22_RS04100	ENOG4105D7Q	type ii secretion system
AMD22_RS04105	ENOG4108VAU	general secretion pathway protein G
AMD22_RS04110	ENOG4105VWV	general secretion pathway protein h
AMD22_RS04115	ENOG4105X5Z	General secretion pathway protein I
AMD22_RS04125	ENOG4108RTD	type II secretion system protein K
AMD22_RS04175	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS04180	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AMD22_RS04185	ENOG4105CE4	GlcNAc 6-P deacetylase
AMD22_RS04195	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AMD22_RS04200	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AMD22_RS04205	ENOG4105C26	Dehydrogenase
AMD22_RS04210	ENOG4105C94	Transporter
AMD22_RS04220	ENOG4108Z33	Thiol disulfide Interchange Protein
AMD22_RS04230	ENOG4106RE7	Cytochrome
AMD22_RS04235	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AMD22_RS04240	ENOG4105CY0	Metallo-Beta-Lactamase
AMD22_RS04255	ENOG4105JJR	Histidine kinase
AMD22_RS04285	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AMD22_RS04300	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AMD22_RS04305	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AMD22_RS04320	ENOG4105C5H	ABC transporter
AMD22_RS04330	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AMD22_RS04335	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AMD22_RS04345	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AMD22_RS04360	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AMD22_RS04365	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AMD22_RS04370	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AMD22_RS04375	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AMD22_RS04395	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AMD22_RS04400	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AMD22_RS04405	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AMD22_RS04410	ENOG4105C08	Histidine kinase
AMD22_RS04415	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AMD22_RS04430	ENOG4105CQB	FAD linked oxidase domain protein
AMD22_RS04435	ENOG4105S2T	inner membrane protein YbcI
AMD22_RS04440	ENOG41082RQ	UPF0102 protein
AMD22_RS04470	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AMD22_RS04475	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AMD22_RS04480	ENOG4105CJN	penicillin-binding protein
AMD22_RS04485	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AMD22_RS04490	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AMD22_RS04495	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AMD22_RS04505	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AMD22_RS04510	ENOG4105DFU	Cell wall formation (By similarity)
AMD22_RS04515	ENOG4105CPF	Cell wall formation (By similarity)
AMD22_RS04520	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AMD22_RS04525	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AMD22_RS04530	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AMD22_RS04535	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AMD22_RS04545	ENOG4105DR5	peptidase
AMD22_RS04550	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AMD22_RS04555	ENOG4105M6F	mutator MutT protein
AMD22_RS04565	ENOG4105SYT	Methylenetetrahydrofolate reductase
AMD22_RS04625	ENOG4105DXX	methyltransferase
AMD22_RS04630	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AMD22_RS04640	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AMD22_RS04670	ENOG4105D6F	Phosphatase
AMD22_RS04685	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AMD22_RS04690	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AMD22_RS04700	ENOG4108RVA	ribokinase
AMD22_RS04705	ENOG4105D9N	nucleoside
AMD22_RS04710	ENOG4105CPC	Aldo Keto reductase
AMD22_RS04720	ENOG4105D05	Receptor
AMD22_RS04740	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AMD22_RS04755	ENOG4105E2B	Taurine dioxygenase
AMD22_RS04765	ENOG4108I0Y	(ABC) transporter
AMD22_RS04770	ENOG4108UJV	acyl-CoA thioesterase i
AMD22_RS04780	ENOG4105DHQ	Histidine kinase
AMD22_RS04790	ENOG41080IJ	Diacylglycerol kinase
AMD22_RS04810	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AMD22_RS04815	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AMD22_RS04830	ENOG4107SM7	Transcriptional regulator
AMD22_RS04835	ENOG4107T8P	acyl-Coa dehydrogenase
AMD22_RS04840	ENOG4105D7T	ABC transporter
AMD22_RS04845	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AMD22_RS04855	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AMD22_RS04860	ENOG4108UZX	fmn reductase
AMD22_RS04885	ENOG4105DEF	Extracellular solute-binding protein, family 5
AMD22_RS04895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AMD22_RS04905	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AMD22_RS04910	ENOG4105NWN	ApaG protein
AMD22_RS04915	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AMD22_RS04920	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AMD22_RS04925	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AMD22_RS04930	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AMD22_RS04945	ENOG4108WBT	adenosyltransferase
AMD22_RS04955	ENOG4105D0A	hydroxylase
AMD22_RS04960	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AMD22_RS04995	ENOG4105DDW	LysR family Transcriptional regulator
AMD22_RS05010	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AMD22_RS05040	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AMD22_RS05065	ENOG4105DXC	membrane
AMD22_RS05075	ENOG4105CX6	glutaminyL-tRNA synthetase
AMD22_RS05095	ENOG4105BZU	Histidine kinase
AMD22_RS05100	ENOG4105WH1	Two component transcriptional regulator luxr family
AMD22_RS05110	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AMD22_RS05120	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AMD22_RS05125	ENOG4105NXH	GreA GreB family elongation factor
AMD22_RS05130	ENOG4105C5Q	Transcriptional regulator
AMD22_RS05145	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AMD22_RS05165	ENOG4105C2M	dna polymerase I
AMD22_RS05195	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AMD22_RS05220	ENOG4105W8H	transhydrogenase (subunit alpha
AMD22_RS05225	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AMD22_RS05240	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AMD22_RS05245	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AMD22_RS05250	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AMD22_RS05255	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AMD22_RS05260	ENOG4108Z66	YbaK ebsC protein
AMD22_RS05280	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AMD22_RS05285	ENOG4107S2Z	UPF0761 membrane protein
AMD22_RS05290	ENOG4107QX9	Thiol disulfide interChange protein
AMD22_RS05305	ENOG4105CSR	polyphosphate kinase 2
AMD22_RS05310	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AMD22_RS05320	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AMD22_RS05325	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AMD22_RS05330	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AMD22_RS05335	ENOG4105QVB	outer membrane lipoprotein LolB
AMD22_RS05340	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AMD22_RS05350	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AMD22_RS05355	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AMD22_RS05360	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AMD22_RS05365	ENOG4105C3G	gtp-binding protein
AMD22_RS05385	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AMD22_RS05395	ENOG4105PM1	preprotein translocase subunit SecE
AMD22_RS05400	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AMD22_RS05405	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AMD22_RS05410	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AMD22_RS05415	ENOG4108VZM	50s ribosomal protein L10
AMD22_RS05420	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AMD22_RS05425	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AMD22_RS05430	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AMD22_RS05440	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AMD22_RS05445	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AMD22_RS05450	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AMD22_RS05455	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AMD22_RS05460	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AMD22_RS05465	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AMD22_RS05475	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMD22_RS05480	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AMD22_RS05490	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AMD22_RS05500	ENOG41083MP	50s ribosomal protein l29
AMD22_RS05515	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AMD22_RS05520	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMD22_RS05530	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AMD22_RS05535	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AMD22_RS05540	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AMD22_RS05555	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AMD22_RS05560	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AMD22_RS05590	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AMD22_RS05605	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AMD22_RS05615	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AMD22_RS05625	ENOG4105CI3	gtp-binding protein typa
AMD22_RS05630	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AMD22_RS05635	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AMD22_RS05640	ENOG4108K3A	Glutathione S-transferase
AMD22_RS05650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AMD22_RS05655	ENOG4105CIS	alcohol dehydrogenase
AMD22_RS05660	ENOG4105CDV	Ompa motb domain protein
AMD22_RS05670	ENOG4108R99	pseudouridine synthase
AMD22_RS05680	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AMD22_RS05685	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AMD22_RS05690	ENOG4108I5D	sulfate abc transporter
AMD22_RS05700	ENOG4108IJ6	ABC transporter
AMD22_RS05710	ENOG4105CPQ	Dehydrogenase
AMD22_RS05725	ENOG4105HSS	phospholipase C
AMD22_RS05740	ENOG4105CVJ	phosphoglycerate mutase
AMD22_RS05745	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AMD22_RS05760	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AMD22_RS05765	ENOG4105ED9	Protein of unknown function (DUF455)
AMD22_RS05775	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
AMD22_RS05785	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AMD22_RS05790	ENOG4105EYK	Phosphatidylglycerophosphatase B
AMD22_RS05795	ENOG4105BZF	Glycosyl transferase (Group 1
AMD22_RS05800	ENOG4105C9X	ppx gppa phosphatase
AMD22_RS05805	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AMD22_RS05810	ENOG4105BZU	Histidine kinase
AMD22_RS05815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AMD22_RS05820	ENOG4105ERG	peptidase m48, ste24p
AMD22_RS05825	ENOG4105VW4	glutaredoxin 3
AMD22_RS05835	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AMD22_RS05990	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AMD22_RS06000	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AMD22_RS06030	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AMD22_RS06035	ENOG41068JE	domain protein
AMD22_RS06040	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AMD22_RS06050	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AMD22_RS06055	ENOG4107RZZ	dna polymerase iii epsilon subunit
AMD22_RS06060	ENOG4108ZF3	Phosphatase
AMD22_RS06075	ENOG4105DKP	glycosyl transferase, family 9
AMD22_RS06080	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AMD22_RS06085	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AMD22_RS06090	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AMD22_RS06100	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AMD22_RS06105	ENOG4105M00	molybdopterin converting factor, subunit 1
AMD22_RS06110	ENOG4108ZAF	Molybdopterin
AMD22_RS06160	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AMD22_RS06165	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AMD22_RS06170	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AMD22_RS06175	ENOG4105K59	histidine triad (HIT) protein
AMD22_RS06195	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AMD22_RS06215	ENOG4108UHJ	MAF-like protein
AMD22_RS06220	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AMD22_RS06225	ENOG4105VGS	50s ribosomal protein l32
AMD22_RS06230	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AMD22_RS06240	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AMD22_RS06245	ENOG4105CHR	reductase
AMD22_RS06255	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AMD22_RS06265	ENOG4105HHA	aminodeoxychorismate lyase
AMD22_RS06270	ENOG4107QRG	dna polymerase iii
AMD22_RS06290	ENOG4108JU7	Transcriptional regulator
AMD22_RS06295	ENOG4105CR4	methylisocitrate lyase
AMD22_RS06300	ENOG4105BZN	citrate synthase
AMD22_RS06305	ENOG4108I0Z	Aconitate hydratase
AMD22_RS06310	ENOG4105YAJ	CopG Arc MetJ
AMD22_RS06315	ENOG4105C7F	AcnD-accessory protein PrpF
AMD22_RS06330	ENOG4105DN3	alpha-2-macroglobulin domain protein
AMD22_RS06345	ENOG4108JQB	penicillin-binding protein 1C
AMD22_RS06370	ENOG4105M3Z	response regulator
AMD22_RS06375	ENOG4107QJR	hflk protein
AMD22_RS06380	ENOG4105EPW	hflc protein
AMD22_RS06390	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AMD22_RS06395	ENOG4105CD8	aminopeptidase N
AMD22_RS06405	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AMD22_RS06410	ENOG4108XFH	Transcriptional regulator
AMD22_RS06480	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AMD22_RS06490	ENOG4105BZP	glycoside hydrolase 15-related
AMD22_RS06495	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AMD22_RS06500	ENOG4105CWX	Alpha-1,2-mannosidase
AMD22_RS06520	ENOG4105C3M	thioredoxin reductase
AMD22_RS06545	ENOG4105C7W	Xanthine dehydrogenase
AMD22_RS06550	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AMD22_RS06555	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AMD22_RS06590	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AMD22_RS06605	ENOG4105C0B	DNA polymerase III (alpha subunit)
AMD22_RS06620	ENOG4105EPD	Oligopeptide transporter, Opt family
AMD22_RS06635	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AMD22_RS06650	ENOG4106AXJ	AraC family transcriptional regulator
AMD22_RS06670	ENOG4105CV8	reductase
AMD22_RS06675	ENOG4105EBR	Carboxylesterase
AMD22_RS06680	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMD22_RS06685	ENOG4105C2C	drug resistance transporter, Bcr CflA
AMD22_RS06700	ENOG4105DIJ	Phosphoethanolamine transferase
AMD22_RS06715	ENOG4105ETX	regulatoR
AMD22_RS06720	ENOG4105DHQ	Histidine kinase
AMD22_RS06735	ENOG4107QMS	site-determining protein
AMD22_RS06740	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AMD22_RS06755	ENOG4105BZU	Histidine kinase
AMD22_RS06760	ENOG4105WH1	Two component transcriptional regulator luxr family
AMD22_RS06800	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AMD22_RS06810	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AMD22_RS06830	ENOG4105C29	acyl-CoA thioesterase
AMD22_RS06845	ENOG4108TGP	Thioesterase superfamily protein
AMD22_RS06850	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AMD22_RS06855	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AMD22_RS06860	ENOG4105K46	50S ribosomal protein l27
AMD22_RS06865	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMD22_RS06875	ENOG4105CJR	Integral membrane protein (MviN
AMD22_RS06880	ENOG4105DTN	riboflavin biosynthesis protein ribF
AMD22_RS06885	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AMD22_RS06890	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AMD22_RS06895	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AMD22_RS06905	ENOG4105E2S	oxidase) subunit II
AMD22_RS06910	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AMD22_RS06915	ENOG4105CCU	oxidase (Subunit III)
AMD22_RS06920	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AMD22_RS06930	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AMD22_RS06935	ENOG4105KAF	membrAne
AMD22_RS06950	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AMD22_RS06960	ENOG4107MMM	Anti-sigma-factor antagonist
AMD22_RS06965	ENOG4105FUA	antagonist
AMD22_RS06970	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AMD22_RS06980	ENOG4105BZU	Histidine kinase
AMD22_RS07005	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AMD22_RS07010	ENOG4105C08	Histidine kinase
AMD22_RS07015	ENOG4107Z5C	methylesterase
AMD22_RS07020	ENOG4105BZU	Histidine kinase
AMD22_RS07025	ENOG4105BZU	Histidine kinase
AMD22_RS07030	ENOG4105CQZ	Histidine kinase
AMD22_RS07045	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AMD22_RS07055	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AMD22_RS07060	ENOG4105CRE	cytochrome C
AMD22_RS07065	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMD22_RS07070	ENOG4107QWG	2-Nitropropane dioxygenase
AMD22_RS07080	ENOG4105K5M	30s ribosomal protein S16
AMD22_RS07085	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AMD22_RS07090	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AMD22_RS07095	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AMD22_RS07120	ENOG4105VEJ	Heat shock protein
AMD22_RS07125	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AMD22_RS07135	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AMD22_RS07145	ENOG4105CNA	YD repeat protein
AMD22_RS07165	ENOG4105CNT	hydrolase family 2
AMD22_RS07170	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AMD22_RS07185	ENOG4105C26	Dehydrogenase
AMD22_RS07190	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS07195	ENOG4105E39	Enoyl-CoA hydratase
AMD22_RS07200	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AMD22_RS07205	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AMD22_RS07215	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AMD22_RS07220	ENOG4105EMN	RNA polymerase sigma factor
AMD22_RS07230	ENOG4105C0H	protease
AMD22_RS07235	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AMD22_RS07240	ENOG4105C3F	Signal peptidase i
AMD22_RS07250	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AMD22_RS07255	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AMD22_RS07260	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AMD22_RS07270	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AMD22_RS07280	ENOG4107ZXU	DSBA oxidoreductase
AMD22_RS07285	ENOG4108QDE	fad dependent oxidoreductase
AMD22_RS07290	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AMD22_RS07295	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AMD22_RS07300	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AMD22_RS07305	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AMD22_RS07310	ENOG4105VEQ	Cold shock protein
AMD22_RS07315	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AMD22_RS07325	ENOG4107QRT	dEAD DEAH box helicase
AMD22_RS07330	ENOG4107T0X	DNA ligase
AMD22_RS07340	ENOG4107T0X	DNA ligase
AMD22_RS07370	ENOG4105CHU	acetyl-coa acetyltransferase
AMD22_RS07390	ENOG4108VKG	metal-dependent hydrolase
AMD22_RS07405	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AMD22_RS07430	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AMD22_RS07440	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AMD22_RS07445	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AMD22_RS07450	ENOG4105F27	Major Facilitator
AMD22_RS07495	ENOG4105M4H	endoribonuclease L-psp
AMD22_RS07500	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AMD22_RS07515	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AMD22_RS07540	ENOG4105K6V	RNA polymerase
AMD22_RS07560	ENOG4108R3D	Electron transport complex
AMD22_RS07570	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AMD22_RS07585	ENOG4105DA5	(ABC) transporter
AMD22_RS07590	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AMD22_RS07595	ENOG4108IQI	permease
AMD22_RS07600	ENOG4107QK5	Homocysteine s-methyltransferase
AMD22_RS07650	ENOG4108YXA	Membrane
AMD22_RS07665	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AMD22_RS07675	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AMD22_RS07680	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AMD22_RS07685	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AMD22_RS07690	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AMD22_RS07695	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AMD22_RS07710	ENOG4105DZP	Membrane-associated zinc metalloprotease
AMD22_RS07715	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AMD22_RS07720	ENOG4105KNE	Phosphatidate cytidylyltransferase
AMD22_RS07725	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AMD22_RS07730	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AMD22_RS07735	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AMD22_RS07745	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AMD22_RS07750	ENOG4105CE9	30S ribosomal protein S2
AMD22_RS07785	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AMD22_RS07790	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AMD22_RS07800	ENOG4105KUZ	arsenate reductase
AMD22_RS07805	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AMD22_RS07810	ENOG4105CAQ	asparagine synthetase
AMD22_RS07820	ENOG4108ESX	Receptor
AMD22_RS07835	ENOG4108UWD	Iron-storage protein
AMD22_RS07840	ENOG4105FQ6	thiopurine methyltransferase
AMD22_RS07850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AMD22_RS07870	ENOG4105CW7	secretion protein, HlyD family
AMD22_RS07875	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AMD22_RS07895	ENOG4105DUX	Transporter
AMD22_RS07925	ENOG4105DGW	oligopeptidase A
AMD22_RS07930	ENOG4108V06	Glutathione peroxidase
AMD22_RS07935	ENOG4105DP0	ferredoxin-NADP reductase
AMD22_RS07945	ENOG4107GFK	fumarate
AMD22_RS07960	ENOG4105HDD	phospholipase
AMD22_RS07970	ENOG4105VEQ	Cold shock protein
AMD22_RS07985	ENOG4105CUZ	uba thif-type nad fad binding protein
AMD22_RS08005	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS08015	ENOG4108K3A	Glutathione S-transferase
AMD22_RS08025	ENOG4105CAQ	asparagine synthetase
AMD22_RS08035	ENOG4105CDU	Replicative dna helicase
AMD22_RS08040	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AMD22_RS08045	ENOG4105CDV	Ompa motb domain protein
AMD22_RS08050	ENOG4105CR8	Transcriptional regulator
AMD22_RS08085	ENOG4105BZU	Histidine kinase
AMD22_RS08095	ENOG4106TD9	Diguanylate cyclase
AMD22_RS08200	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AMD22_RS08205	ENOG4108Z1B	Cyclase dehydrase
AMD22_RS08215	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AMD22_RS08220	ENOG41090R7	Ferric uptake
AMD22_RS08225	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AMD22_RS08230	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AMD22_RS08235	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMD22_RS08240	ENOG4105CFG	Acts as a chaperone (By similarity)
AMD22_RS08245	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AMD22_RS08280	ENOG4105C5Q	Transcriptional regulator
AMD22_RS08285	ENOG4105BZ1	(ABC) transporter
AMD22_RS08295	ENOG4108URH	decarboxylase
AMD22_RS08305	ENOG4105C7S	Dehydrogenase
AMD22_RS08310	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AMD22_RS08320	ENOG4105EZE	Cupin 4 family protein
AMD22_RS08330	ENOG4107QTF	adenylosuccinate lyase
AMD22_RS08340	ENOG4105C37	(CBS) domain
AMD22_RS08370	ENOG4105CZV	ABC transporter
AMD22_RS08375	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AMD22_RS08385	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AMD22_RS08390	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AMD22_RS08395	ENOG41069P5	Protein slyX homolog
AMD22_RS08410	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS08420	ENOG4105D7K	pfkb domain protein
AMD22_RS08430	ENOG4105C3R	Methionine synthase
AMD22_RS08435	ENOG4105C3R	Methionine synthase
AMD22_RS08440	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AMD22_RS08445	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS08460	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AMD22_RS08470	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AMD22_RS08475	ENOG4105BZU	Histidine kinase
AMD22_RS08480	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AMD22_RS08490	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AMD22_RS08495	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AMD22_RS08500	ENOG4105E2Z	phosphate ABC transporter (Permease
AMD22_RS08505	ENOG4105C8U	phosphate abc transporter
AMD22_RS08510	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AMD22_RS08530	ENOG4107B2H	carbonic anhydrase
AMD22_RS08535	ENOG4105CHH	sulfate transporter
AMD22_RS08540	ENOG4105CSM	endonuclease III
AMD22_RS08550	ENOG4105E39	Enoyl-CoA hydratase
AMD22_RS08555	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AMD22_RS08560	ENOG4105P8F	nudix hydrolase
AMD22_RS08565	ENOG4105KHC	sulfurtransferase
AMD22_RS08595	ENOG4105C5H	ABC transporter
AMD22_RS08600	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AMD22_RS08605	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AMD22_RS08630	ENOG4105CJB	Exodeoxyribonuclease I
AMD22_RS08635	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AMD22_RS08640	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AMD22_RS08650	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AMD22_RS08655	ENOG41077A9	carbonic anhydrase
AMD22_RS08700	ENOG4105WH1	Two component transcriptional regulator luxr family
AMD22_RS08735	ENOG4105C5S	asparaginyl-tRNA synthetase
AMD22_RS08740	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AMD22_RS08745	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AMD22_RS08750	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AMD22_RS08755	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AMD22_RS08765	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AMD22_RS08775	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AMD22_RS08780	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AMD22_RS08785	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AMD22_RS08795	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AMD22_RS08800	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AMD22_RS08805	ENOG4105DZG	Dehydrogenase
AMD22_RS08815	ENOG4105CGP	Urocanate hydratase
AMD22_RS08825	ENOG4105C84	Histidine ammonia-lyase
AMD22_RS08830	ENOG4105CI2	imidazolone-5-propionate hydrolase
AMD22_RS08875	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AMD22_RS08880	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AMD22_RS08885	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AMD22_RS08895	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AMD22_RS08910	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AMD22_RS08915	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AMD22_RS08920	ENOG4105CC0	LysR family Transcriptional regulator
AMD22_RS08935	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS08965	ENOG4105BZU	Histidine kinase
AMD22_RS08985	ENOG4105KWW	Biogenesis protein
AMD22_RS08990	ENOG4107QX9	Thiol disulfide interChange protein
AMD22_RS08995	ENOG4105DA4	cytochrome c-type biogenesis protein
AMD22_RS09000	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AMD22_RS09010	ENOG41060IM	Heme exporter protein
AMD22_RS09025	ENOG4105EMN	RNA polymerase sigma factor
AMD22_RS09080	ENOG4105EGZ	biosynthesis protein
AMD22_RS09110	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AMD22_RS09120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AMD22_RS09135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AMD22_RS09145	ENOG41079KZ	Major Facilitator Superfamily
AMD22_RS09150	ENOG4105DEN	Luciferase family
AMD22_RS09175	ENOG4105CJ3	phosphate transporter
AMD22_RS09190	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AMD22_RS09200	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AMD22_RS09205	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AMD22_RS09215	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AMD22_RS09220	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AMD22_RS09225	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AMD22_RS09230	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AMD22_RS09235	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AMD22_RS09240	ENOG4108DG9	Smr protein MutS2
AMD22_RS09245	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AMD22_RS09250	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AMD22_RS09255	ENOG4108UM1	dedA family
AMD22_RS09260	ENOG4108K5P	(LipO)protein
AMD22_RS09270	ENOG4105HBR	Rna-binding protein
AMD22_RS09275	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AMD22_RS09280	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AMD22_RS09285	ENOG4105EEI	dihydropteroate synthase
AMD22_RS09290	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AMD22_RS09300	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AMD22_RS09305	ENOG4107TH8	cina domain protein
AMD22_RS09315	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AMD22_RS09320	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AMD22_RS09325	ENOG4105Y3E	Modulates RecA activity (By similarity)
AMD22_RS09330	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AMD22_RS09345	ENOG4107SDU	Methyl-accepting chemotaxis
AMD22_RS09360	ENOG4105CWB	LysR family transcriptional Regulator
AMD22_RS09385	ENOG4105DWF	phosphomethylpyrimidine kinase
AMD22_RS09400	ENOG4108IAB	Phoh family
AMD22_RS09405	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMD22_RS09420	ENOG4107TUS	Dihydrodipicolinate synthase
AMD22_RS09430	ENOG4108Z4U	Ferredoxin
AMD22_RS09435	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AMD22_RS09445	ENOG4105CXK	mandelate racemase muconate lactonizing
AMD22_RS09450	ENOG4108RTU	Aldolase
AMD22_RS09500	ENOG4105CMG	Carbohydrate kinase
AMD22_RS09505	ENOG4105C93	Xylose Isomerase
AMD22_RS09520	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AMD22_RS09525	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AMD22_RS09535	ENOG4105DJ0	Poly(A) Polymerase
AMD22_RS09540	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMD22_RS09545	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AMD22_RS09550	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AMD22_RS09555	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AMD22_RS09560	ENOG4107QP8	phosphohexose isomerase
AMD22_RS09595	ENOG4105KU2	hydrolase family 5
AMD22_RS09600	ENOG4108UYB	regulatoR
AMD22_RS09610	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AMD22_RS09615	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AMD22_RS09620	ENOG4105CSH	Transporter
AMD22_RS09630	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AMD22_RS09635	ENOG4105D4A	Cell wall formation (By similarity)
AMD22_RS09640	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AMD22_RS09655	ENOG4105C26	Dehydrogenase
AMD22_RS09670	ENOG4105CND	Glycosyl transferase, family 2
AMD22_RS09675	ENOG4107BJW	polysaccharide deacetylase
AMD22_RS09690	ENOG41067NU	
AMD22_RS09695	ENOG41067NU	
AMD22_RS09735	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AMD22_RS09740	ENOG4105CUT	histidyl-tRNA synthetase
AMD22_RS09750	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AMD22_RS09755	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AMD22_RS09760	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AMD22_RS09765	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AMD22_RS09770	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AMD22_RS09775	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AMD22_RS09780	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AMD22_RS09785	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AMD22_RS09800	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AMD22_RS09805	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AMD22_RS09810	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AMD22_RS09815	ENOG4105CUB	amino acid
AMD22_RS09820	ENOG4105CUB	amino acid
AMD22_RS09830	ENOG4108JQ1	Dehydrogenase
AMD22_RS09835	ENOG4105CQB	FAD linked oxidase domain protein
AMD22_RS09855	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AMD22_RS09865	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AMD22_RS09885	ENOG4105CE1	Ferrous iron transport protein b
AMD22_RS09900	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AMD22_RS09905	ENOG4108RPX	mosc domain containing protein
AMD22_RS09910	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AMD22_RS09915	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AMD22_RS09925	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AMD22_RS09930	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AMD22_RS09940	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AMD22_RS09985	ENOG4105DY9	regulatoR
AMD22_RS09995	ENOG4105CRK	lysyL-tRNA synthetase
AMD22_RS10000	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AMD22_RS10005	ENOG4105BZU	Histidine kinase
AMD22_RS10010	ENOG41060WC	Enoyl-CoA hydratase
AMD22_RS10015	ENOG4105CEY	Amp-dependent synthetase and ligase
AMD22_RS10025	ENOG4107QM5	aconitate hydratase
AMD22_RS10040	ENOG4107QIJ	Aconitate hydratase 2
AMD22_RS10045	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AMD22_RS10050	ENOG4105BZU	Histidine kinase
AMD22_RS10055	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AMD22_RS10060	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AMD22_RS10065	ENOG4105BZU	Histidine kinase
AMD22_RS10070	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10075	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10080	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10090	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10095	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10100	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10105	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10120	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10135	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS10140	ENOG4105CBS	Chea signal transduction histidine kinase
AMD22_RS10145	ENOG4108VYJ	response regulator receiver protein
AMD22_RS10155	ENOG4108V3W	Chemotaxis protein, CheW
AMD22_RS10165	ENOG4105ER2	Ompa motb domain protein
AMD22_RS10170	ENOG4105E14	MotA TolQ exbB proton channel
AMD22_RS10255	ENOG4105C4X	radical SAM domain protein
AMD22_RS10280	ENOG4108VYJ	response regulator receiver protein
AMD22_RS10285	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AMD22_RS10295	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AMD22_RS10300	ENOG4105D7B	Flagellar biosynthesis protein flha
AMD22_RS10305	ENOG4105D00	flagellar biosynthetic protein flhB
AMD22_RS10310	ENOG4105BZU	Histidine kinase
AMD22_RS10320	ENOG4105BZU	Histidine kinase
AMD22_RS10325	ENOG4105BZU	Histidine kinase
AMD22_RS10330	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AMD22_RS10335	ENOG4105VS8	Flagellar biosynthetic protein fliq
AMD22_RS10340	ENOG4105CN7	Flagellar biosynthetic protein FliP
AMD22_RS10345	ENOG4105K0P	flagellar biosynthesis protein
AMD22_RS10350	ENOG4105DD5	Flagellar motor switch protein
AMD22_RS10355	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AMD22_RS10375	ENOG4108JIR	Flagellum-specific ATP synthase
AMD22_RS10385	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AMD22_RS10390	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AMD22_RS10395	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AMD22_RS10400	ENOG4107RGC	Glycosyl transferase, family 2
AMD22_RS10425	ENOG4105CHR	reductase
AMD22_RS10430	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AMD22_RS10435	ENOG4108P1X	synthase
AMD22_RS10455	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AMD22_RS10460	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AMD22_RS10480	ENOG4105MQ3	flagellar protein FliS
AMD22_RS10485	ENOG4107W9T	flagellar hook-associated
AMD22_RS10495	ENOG4105DTJ	flagellar hook-associated protein
AMD22_RS10505	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AMD22_RS10510	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AMD22_RS10515	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AMD22_RS10520	ENOG4105CGA	flagellar basal-body rod protein FlgG
AMD22_RS10525	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AMD22_RS10530	ENOG4105BZE	flagellar hook protein, FlgE
AMD22_RS10535	ENOG410822I	Flagellar hook capping protein
AMD22_RS10540	ENOG4108ZC9	flagellar basal-body rod protein flgc
AMD22_RS10570	ENOG4105BZU	Histidine kinase
AMD22_RS10575	ENOG4105BZU	Histidine kinase
AMD22_RS10585	ENOG4105BZU	Histidine kinase
AMD22_RS10605	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AMD22_RS10620	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AMD22_RS10630	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AMD22_RS10640	ENOG4105C3M	thioredoxin reductase
AMD22_RS10645	ENOG4105CNU	cell division protein FtsK
AMD22_RS10655	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AMD22_RS10665	ENOG4105D1H	recombination factor protein RarA
AMD22_RS10670	ENOG41082MI	Protein CrcB homolog
AMD22_RS10680	ENOG4105CHU	acetyl-coa acetyltransferase
AMD22_RS10700	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AMD22_RS10710	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AMD22_RS10720	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AMD22_RS10725	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AMD22_RS10730	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AMD22_RS10735	ENOG4105D06	uba thif-type nad fad binding protein
AMD22_RS10770	ENOG4105CGK	Exodeoxyribonuclease III
AMD22_RS10780	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AMD22_RS10785	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AMD22_RS10800	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AMD22_RS10805	ENOG4105KST	dependent repressor
AMD22_RS10810	ENOG4108Z6B	deaminase
AMD22_RS10815	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AMD22_RS10830	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AMD22_RS10850	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AMD22_RS10860	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AMD22_RS10885	ENOG4105BZM	domain protein
AMD22_RS10890	ENOG4105BZU	Histidine kinase
AMD22_RS10930	ENOG4105N7H	Cytochrome
AMD22_RS10955	ENOG4108UHU	Aldolase
AMD22_RS10960	ENOG4105C01	Dihydroxy-acid dehydratase
AMD22_RS10965	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AMD22_RS10970	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AMD22_RS10985	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AMD22_RS10990	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AMD22_RS11015	ENOG410681N	tpr repeat protein
AMD22_RS11025	ENOG4105D60	lipoprotein releasing system transmembrane protein
AMD22_RS11030	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AMD22_RS11040	ENOG4108EC8	DNA internalization-related competence protein ComEC
AMD22_RS11050	ENOG4105M15	transport protein ExbD
AMD22_RS11055	ENOG4105BZ1	(ABC) transporter
AMD22_RS11060	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AMD22_RS11065	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AMD22_RS11080	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AMD22_RS11085	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AMD22_RS11105	ENOG4105C0W	non-ribosomal peptide synthetase
AMD22_RS11110	ENOG4105CEY	Amp-dependent synthetase and ligase
AMD22_RS11140	ENOG4107QQG	Dehydrogenase
AMD22_RS11150	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AMD22_RS11160	ENOG4105C72	UPF0176 protein
AMD22_RS11170	ENOG4105C03	ribonuclease
AMD22_RS11175	ENOG4105EI2	Pseudouridine synthase
AMD22_RS11180	ENOG4108NST	exported protein
AMD22_RS11185	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AMD22_RS11195	ENOG41090A4	Pterin carbinolamine dehydratase
AMD22_RS11200	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AMD22_RS11245	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AMD22_RS11255	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AMD22_RS11290	ENOG4105W39	Membrane
AMD22_RS11325	ENOG4105DY9	regulatoR
AMD22_RS11370	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AMD22_RS11395	ENOG4108N8X	transition metal ion binding
AMD22_RS11410	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AMD22_RS11425	ENOG4107SFI	Major Facilitator superfamily
AMD22_RS11445	ENOG4105CHJ	isochorismatase hydrolase
AMD22_RS11460	ENOG4105WH1	Two component transcriptional regulator luxr family
AMD22_RS11480	ENOG4105DND	Transcriptional regulator
AMD22_RS11490	ENOG4105EVH	UPF0753 protein
AMD22_RS11515	ENOG4108YGG	dna repair protein
AMD22_RS11540	ENOG4105DFP	Integrase
AMD22_RS11555	ENOG4105E0K	tonB-dependent siderophore receptor
AMD22_RS11570	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
AMD22_RS11595	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS11605	ENOG4105NRM	Membrane
AMD22_RS11635	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AMD22_RS11640	ENOG4108JJA	ABC, transporter
AMD22_RS11695	ENOG4105NI8	Cytosine-specific methyltransferase
AMD22_RS11765	ENOG4107AQZ	Membrane
AMD22_RS11780	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
AMD22_RS11785	ENOG4108K3A	Glutathione S-transferase
AMD22_RS11790	ENOG4105CTU	Proline racemase
AMD22_RS11805	ENOG4105DJ2	Major Facilitator Superfamily
AMD22_RS11810	ENOG4105R1U	AraC Family Transcriptional Regulator
AMD22_RS11960	ENOG41088T4	Helicase IV
AMD22_RS12040	ENOG4105ZXK	Dehydrogenase
AMD22_RS12060	ENOG4105W5Q	DNA repair protein (RadC
AMD22_RS12095	ENOG4105DFP	Integrase
AMD22_RS12100	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AMD22_RS12105	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AMD22_RS12110	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AMD22_RS12120	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AMD22_RS12125	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AMD22_RS12135	ENOG4105ESV	Glycosyl transferase, family 4
AMD22_RS12140	ENOG4105CFV	Tetratricopeptide repeat protein
AMD22_RS12150	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AMD22_RS12155	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AMD22_RS12160	ENOG4105CAT	Cytidine monophosphate kinase
AMD22_RS12175	ENOG4105DWY	Agmatine deiminase
AMD22_RS12205	ENOG4105DRS	transport system, permease
AMD22_RS12210	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AMD22_RS12240	ENOG4105K9H	YciI-like protein
AMD22_RS12245	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AMD22_RS12250	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AMD22_RS12255	ENOG4105FE9	pseudouridine synthase
AMD22_RS12275	ENOG4105CHM	Aminotransferase
AMD22_RS12280	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AMD22_RS12285	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AMD22_RS12290	ENOG41060IM	Heme exporter protein
AMD22_RS12300	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AMD22_RS12305	ENOG4105DA4	cytochrome c-type biogenesis protein
AMD22_RS12315	ENOG4105KWW	Biogenesis protein
AMD22_RS12320	ENOG4108M1T	Cytochrome c-type biogenesis protein
AMD22_RS12335	ENOG4108JJ8	(ABC) transporter
AMD22_RS12340	ENOG4108JJ9	ABC, transporter
AMD22_RS12345	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AMD22_RS12350	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AMD22_RS12375	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AMD22_RS12380	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AMD22_RS12390	ENOG4105CH7	arginosuccinase
AMD22_RS12395	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AMD22_RS12405	ENOG4105CAS	nag kinase
AMD22_RS12420	ENOG4105CDH	Citrulline--aspartate ligase
AMD22_RS12425	ENOG4105DBV	ornithine carbamoyltransferase
AMD22_RS12435	ENOG4105C8N	cysteinyl-tRNA synthetase
AMD22_RS12440	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AMD22_RS12460	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AMD22_RS12465	ENOG4105CD3	dihydroorotase
AMD22_RS12485	ENOG4105CPD	ethanolamine ammonia-lyase
AMD22_RS12490	ENOG4107FQ9	ethanolamine ammonia-lyase
AMD22_RS12535	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AMD22_RS12540	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AMD22_RS12545	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AMD22_RS12555	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AMD22_RS12560	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AMD22_RS12565	ENOG4105BZU	Histidine kinase
AMD22_RS12580	ENOG4105ECY	inositol monophosphatase
AMD22_RS12585	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AMD22_RS12600	ENOG4105C5H	ABC transporter
AMD22_RS12605	ENOG4105C1J	atp-dependent rna helicase
AMD22_RS12610	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AMD22_RS12615	ENOG4105CNG	UPF0061 protein
AMD22_RS12625	ENOG4108RXX	maleylacetoacetate isomerase
AMD22_RS12630	ENOG4105VEQ	Cold shock protein
AMD22_RS12635	ENOG4108VWS	Yaeq family
AMD22_RS12640	ENOG4105CBX	hi0933 family
AMD22_RS12650	ENOG4105D0M	Protease HtpX homolog
AMD22_RS12655	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AMD22_RS12660	ENOG4105CHR	reductase
AMD22_RS12680	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AMD22_RS12685	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AMD22_RS12690	ENOG4105K8N	protein family UPF0079, ATPase
AMD22_RS12695	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AMD22_RS12700	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AMD22_RS12705	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AMD22_RS12715	ENOG4105E6M	Sulphatase-modifying factor protein
AMD22_RS12725	ENOG4105DQE	DNA ligase
AMD22_RS12800	ENOG4105C26	Dehydrogenase
AMD22_RS12895	ENOG4108V3W	Chemotaxis protein, CheW
AMD22_RS12900	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS12905	ENOG4108VX5	3-methyladenine DNA glycosylase
AMD22_RS12910	ENOG4107QRT	dEAD DEAH box helicase
AMD22_RS12925	ENOG4105KB2	stringent starvation protein b
AMD22_RS12930	ENOG4107MKT	Stringent starvation protein a
AMD22_RS12935	ENOG4105EIX	cytochrome c1
AMD22_RS12940	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AMD22_RS12945	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AMD22_RS12950	ENOG4105E4C	Lytic transglycosylase catalytic
AMD22_RS12965	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AMD22_RS12970	ENOG4105C9A	Phoh family
AMD22_RS12980	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AMD22_RS12990	ENOG4108JU5	Magnesium and cobalt efflux protein
AMD22_RS13015	ENOG4105D38	putrescine abc transporter
AMD22_RS13020	ENOG4105F38	ABC transporter, permease
AMD22_RS13025	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AMD22_RS13045	ENOG4107RUE	extracellular solute-binding protein family 1
AMD22_RS13050	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AMD22_RS13065	ENOG4105CFQ	glutamine synthetase
AMD22_RS13070	ENOG4105CJP	fad dependent oxidoreductase
AMD22_RS13080	ENOG4105W3S	hemerythrin-like, metal-binding protein
AMD22_RS13085	ENOG4105CSH	Transporter
AMD22_RS13095	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AMD22_RS13100	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AMD22_RS13120	ENOG4106BRA	Membrane
AMD22_RS13125	ENOG4105BZU	Histidine kinase
AMD22_RS13130	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AMD22_RS13135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AMD22_RS13140	ENOG4105C7I	Dehydrogenase
AMD22_RS13150	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AMD22_RS13155	ENOG4105BZS	acriflavin resistance protein
AMD22_RS13160	ENOG4108M60	Transcriptional regulator
AMD22_RS13165	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AMD22_RS13170	ENOG4105DE4	1-phosphofructokinase
AMD22_RS13175	ENOG4105DM4	PTS System
AMD22_RS13210	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AMD22_RS13215	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AMD22_RS13220	ENOG4105VIE	preprotein translocase, subunit YajC
AMD22_RS13225	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AMD22_RS13230	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AMD22_RS13270	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AMD22_RS13275	ENOG4105E08	Glycoside hydrolase, family 9
AMD22_RS13285	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AMD22_RS13290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AMD22_RS13305	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AMD22_RS13310	ENOG4106H78	methyltransferase
AMD22_RS13315	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AMD22_RS13385	ENOG4107QTZ	amino acid
AMD22_RS13400	ENOG4105DC7	peptidase M24
AMD22_RS13410	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AMD22_RS13425	ENOG41080HI	glycine oxidase
AMD22_RS13430	ENOG4105CTU	Proline racemase
AMD22_RS13440	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AMD22_RS13445	ENOG4105CEN	a g-specific adenine glycosylase
AMD22_RS13450	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AMD22_RS13455	ENOG4105CQZ	Histidine kinase
AMD22_RS13470	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
AMD22_RS13485	ENOG4105QNF	Outer membrane lipoprotein
AMD22_RS13495	ENOG4105CSU	acyl-Coa dehydrogenase
AMD22_RS13505	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AMD22_RS13525	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AMD22_RS13530	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AMD22_RS13535	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AMD22_RS13560	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AMD22_RS13570	ENOG4107Y2G	Glycosyl transferase (Group 1
AMD22_RS13595	ENOG4105D3Q	Sugar transferase
AMD22_RS13615	ENOG4105WJX	transcriptional regulator MERR family
AMD22_RS13625	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AMD22_RS13630	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AMD22_RS13645	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AMD22_RS13650	ENOG4105C22	threonyL-tRNA synthetase
AMD22_RS13655	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS13665	ENOG4107RBJ	symporter
AMD22_RS13690	ENOG4105CG3	alpha amylase, catalytic region
AMD22_RS13740	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
AMD22_RS13760	ENOG4105CMA	conjugation trbi family protein
AMD22_RS13795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AMD22_RS13865	ENOG4105ED4	portal protein
AMD22_RS13910	ENOG4105NVB	glycoside hydrolase, family 19
AMD22_RS14005	ENOG4108HRK	Histidine kinase
AMD22_RS14010	ENOG4105EWT	decarboxylase family
AMD22_RS14015	ENOG4108KPZ	tonB-dependent Receptor
AMD22_RS14020	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AMD22_RS14030	ENOG4105M2J	Glutaredoxin
AMD22_RS14035	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AMD22_RS14040	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AMD22_RS14045	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AMD22_RS14055	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AMD22_RS14065	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AMD22_RS14075	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AMD22_RS14080	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AMD22_RS14085	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AMD22_RS14090	ENOG4105CHV	Transcription elongation factor NusA
AMD22_RS14095	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AMD22_RS14105	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AMD22_RS14110	ENOG4105C8S	subunit m
AMD22_RS14115	ENOG4105D65	subunit l
AMD22_RS14125	ENOG4105DF2	NADH dehydrogenase subunit j
AMD22_RS14130	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AMD22_RS14135	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AMD22_RS14140	ENOG4107R0R	NADH dehydrogenase subunit g
AMD22_RS14145	ENOG4107QIZ	NADH dehydrogenase
AMD22_RS14150	ENOG4105GKE	subunit e
AMD22_RS14155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AMD22_RS14160	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMD22_RS14165	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AMD22_RS14170	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMD22_RS14185	ENOG4105CP7	Triose-phosphate isomerase
AMD22_RS14190	ENOG4107FW0	short-chain dehydrogenase reductase
AMD22_RS14205	ENOG4105BZU	Histidine kinase
AMD22_RS14225	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AMD22_RS14230	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AMD22_RS14235	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AMD22_RS14245	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AMD22_RS14255	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AMD22_RS14260	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AMD22_RS14280	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AMD22_RS14285	ENOG4105C5I	Dehydrogenase
AMD22_RS14290	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AMD22_RS14295	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AMD22_RS14305	ENOG4105DJ4	phosphatidylserine decarboxylase
AMD22_RS14315	ENOG4105D7A	ATP-binding protein
AMD22_RS14320	ENOG4107VIJ	nudix hydrolase
AMD22_RS14335	ENOG4108RRZ	Transcription elongation factor GreB
AMD22_RS14340	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AMD22_RS14365	ENOG4105DHP	deoxycytidine triphosphate deaminase
AMD22_RS14390	ENOG4105C9K	Endothelin-converting enzyme 1
AMD22_RS14395	ENOG4105C9K	Endothelin-converting enzyme 1
AMD22_RS14415	ENOG4105DC8	reductase
AMD22_RS14420	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AMD22_RS14430	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AMD22_RS14435	ENOG4105K4H	Nlp p60 protein
AMD22_RS14440	ENOG4105K4H	Nlp p60 protein
AMD22_RS14450	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AMD22_RS14460	ENOG4105G6Z	alkaline phosphatase
AMD22_RS14465	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AMD22_RS14470	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AMD22_RS14475	ENOG4105CTB	Polyprenyl synthetase
AMD22_RS14490	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AMD22_RS14495	ENOG4105N42	UPF0307 protein
AMD22_RS14500	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AMD22_RS14510	ENOG4105QD6	exported protein
AMD22_RS14515	ENOG4105C03	ribonuclease
AMD22_RS14520	ENOG4108Z03	MAF-like protein
AMD22_RS14525	ENOG4105MPN	Membrane
AMD22_RS14540	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AMD22_RS14555	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AMD22_RS14570	ENOG4105C8T	Leucyl-tRNA synthetase
AMD22_RS14580	ENOG4107QR8	Thioredoxin
AMD22_RS14605	ENOG4105WG9	Conserved Protein
AMD22_RS14650	ENOG4105BZ1	(ABC) transporter
AMD22_RS14675	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AMD22_RS14680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AMD22_RS14685	ENOG4105BZU	Histidine kinase
AMD22_RS14695	ENOG4105FQP	Beta-lactamase
AMD22_RS14700	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AMD22_RS14725	ENOG4105FE9	pseudouridine synthase
AMD22_RS14730	ENOG4105BZU	Histidine kinase
AMD22_RS14795	ENOG4105CMQ	Chloride channel
AMD22_RS14815	ENOG4105UGU	tonB-dependent Receptor
AMD22_RS14845	ENOG4108FN7	Aldo keto reductase
AMD22_RS14850	ENOG4105F27	Major Facilitator
AMD22_RS14855	ENOG4105CC0	LysR family Transcriptional regulator
AMD22_RS14865	ENOG4105CF7	AraC family transcriptional regulator
AMD22_RS14875	ENOG4108JGH	Tetr family transcriptional regulator
AMD22_RS14880	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AMD22_RS14885	ENOG4105BZS	acriflavin resistance protein
AMD22_RS14890	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AMD22_RS14900	ENOG4105MYN	Zinc uptake regulation protein
AMD22_RS14905	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AMD22_RS14930	ENOG4105CT7	inner membrane cred family protein
AMD22_RS14940	ENOG4105EB3	Histidine kinase
AMD22_RS14945	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AMD22_RS14950	ENOG4105D6S	protein involved in catabolism of external DNA
AMD22_RS14960	ENOG4108JA2	transcriptioN-repair coupling factor
AMD22_RS14995	ENOG4105CBS	Chea signal transduction histidine kinase
AMD22_RS15000	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS15005	ENOG4108V3W	Chemotaxis protein, CheW
AMD22_RS15010	ENOG4105BZU	Histidine kinase
AMD22_RS15015	ENOG4105BZU	Histidine kinase
AMD22_RS15020	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AMD22_RS15025	ENOG4107RZC	phospholipase d
AMD22_RS15030	ENOG4105C9K	Endothelin-converting enzyme 1
AMD22_RS15040	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AMD22_RS15045	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AMD22_RS15055	ENOG4105EUB	pirin domain protein
AMD22_RS15070	ENOG4105EUB	pirin domain protein
AMD22_RS15075	ENOG4105D22	carbon starvation protein
AMD22_RS15080	ENOG4105VCD	cytoplasmic protein
AMD22_RS15135	ENOG4105C7W	Xanthine dehydrogenase
AMD22_RS15140	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AMD22_RS15145	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AMD22_RS15160	ENOG4108UUM	single-stranded DNA-binding protein
AMD22_RS15165	ENOG4105EAH	synthase
AMD22_RS15175	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AMD22_RS15190	ENOG4105CFH	Aspartokinase
AMD22_RS15195	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AMD22_RS15200	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AMD22_RS15210	ENOG4108Z9K	Osmotically inducible protein
AMD22_RS15215	ENOG4105CXT	aspartate transcarbamylase
AMD22_RS15220	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AMD22_RS15225	ENOG4108UJU	UPF0301 protein
AMD22_RS15235	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AMD22_RS15245	ENOG4108E16	pectate lyase
AMD22_RS15250	ENOG4105CZX	twitching motility protein
AMD22_RS15255	ENOG4105CZX	twitching motility protein
AMD22_RS15260	ENOG4105DFA	alanine racemase domain protein
AMD22_RS15265	ENOG4105II7	pyrroline-5-carboxylate reductase
AMD22_RS15275	ENOG4105FAA	peptidase M23
AMD22_RS15295	ENOG4108Z0Z	intracellular protease Pfpi family
AMD22_RS15315	ENOG4105C3K	feS assembly ATPase SufC
AMD22_RS15320	ENOG4105JRK	feS assembly protein SufD
AMD22_RS15325	ENOG4105C9B	Cysteine desulfurase
AMD22_RS15335	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AMD22_RS15340	ENOG4108IU3	tonb-dependent siderophore receptor
AMD22_RS15345	ENOG4107E2E	PKHD-type hydroxylase
AMD22_RS15370	ENOG4105CJ2	(LipO)protein
AMD22_RS15375	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AMD22_RS15390	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AMD22_RS15395	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AMD22_RS15405	ENOG4105EHM	Aminoglycoside phosphotransferase
AMD22_RS15410	ENOG4108S0S	Nucleotidyl transferase
AMD22_RS15420	ENOG4105C02	permease
AMD22_RS15430	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AMD22_RS15440	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AMD22_RS15460	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AMD22_RS15470	ENOG4105C2X	Arabinose 5-phosphate isomerase
AMD22_RS15475	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AMD22_RS15485	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AMD22_RS15490	ENOG4108IUZ	ABC transporter
AMD22_RS15495	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AMD22_RS15500	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AMD22_RS15505	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AMD22_RS15510	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AMD22_RS15515	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AMD22_RS15525	ENOG41080Z8	PHOSPHOCARRIER protein
AMD22_RS15530	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AMD22_RS15535	ENOG4105CJW	magnesium transporter
AMD22_RS15540	ENOG4107UWA	esterase
AMD22_RS15545	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AMD22_RS15550	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AMD22_RS15560	ENOG4105C85	amino acid
AMD22_RS15565	ENOG4108NFF	pectate lyase
AMD22_RS15585	ENOG4105CUB	amino acid
AMD22_RS15595	ENOG4108MHS	Lysyl endopeptidase
AMD22_RS15605	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AMD22_RS15610	ENOG4105QV4	Tryptophan halogenase
AMD22_RS15635	ENOG4108Z4X	TRANSCRIPTIONal
AMD22_RS15650	ENOG4106032	Glutathionylspermidine synthase
AMD22_RS15675	ENOG4108P9J	Phage shock protein A
AMD22_RS15685	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AMD22_RS15690	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AMD22_RS15695	ENOG4105D49	3-dehydroquinate synthase
AMD22_RS15705	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AMD22_RS15775	ENOG4108JUA	Transcriptional regulator
AMD22_RS15780	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AMD22_RS15785	ENOG4105BZU	Histidine kinase
AMD22_RS15790	ENOG4105BZU	Histidine kinase
AMD22_RS15800	ENOG4105BZU	Histidine kinase
AMD22_RS15805	ENOG4108YYC	ycei family
AMD22_RS15825	ENOG4105EJQ	L-serine dehydratase
AMD22_RS15835	ENOG4105CFH	Aspartokinase
AMD22_RS15840	ENOG4105C28	cystathionine
AMD22_RS15845	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AMD22_RS15850	ENOG4105DR5	peptidase
AMD22_RS15855	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AMD22_RS15860	ENOG4108UT2	hemolysin iii
AMD22_RS15865	ENOG41066T0	asmA family
AMD22_RS15870	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AMD22_RS15880	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AMD22_RS15885	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AMD22_RS15895	ENOG4105D05	Receptor
AMD22_RS15905	ENOG4108IG5	Transcriptional regulator
AMD22_RS15915	ENOG4107QPN	acyl-Coa dehydrogenase
AMD22_RS15940	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AMD22_RS15945	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AMD22_RS15960	ENOG4105KK4	UPF0060 membrane protein
AMD22_RS15965	ENOG4105DXN	mazG family
AMD22_RS15970	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AMD22_RS15975	ENOG4107RK2	ADP-ribose diphosphatase NudE
AMD22_RS15985	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AMD22_RS15990	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AMD22_RS16005	ENOG4105VRS	hydrolase family 18
AMD22_RS16035	ENOG4107QTZ	amino acid
AMD22_RS16045	ENOG4105F8D	glycoside hydrolase family 4
AMD22_RS16055	ENOG4105CWX	Alpha-1,2-mannosidase
AMD22_RS16090	ENOG4106N3A	copper homeostasis protein cutc
AMD22_RS16105	ENOG4105D9U	N-acetyltransferase
AMD22_RS16125	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS16135	ENOG4105M3Z	response regulator
AMD22_RS16140	ENOG4108UNF	response regulator
AMD22_RS16145	ENOG4105D7Z	glutathione synthase
AMD22_RS16155	ENOG41065RQ	ADP-ribosylation crystallin J1
AMD22_RS16160	ENOG41072GX	Peptidase M22 Glycoprotease
AMD22_RS16165	ENOG4105DVT	helicase
AMD22_RS16175	ENOG4105BZ4	penicillin-binding protein
AMD22_RS16190	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AMD22_RS16195	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AMD22_RS16200	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AMD22_RS16205	ENOG4105Z85	coenzyme PQQ synthesis
AMD22_RS16210	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AMD22_RS16225	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AMD22_RS16235	ENOG4105CQ7	ATP-dependent helicase
AMD22_RS16245	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AMD22_RS16280	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS16300	ENOG410903D	sensor protein
AMD22_RS16305	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AMD22_RS16315	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AMD22_RS16325	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AMD22_RS16330	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AMD22_RS16345	ENOG4105E02	MotA TolQ exbB proton channel
AMD22_RS16350	ENOG4107YD3	Thioesterase
AMD22_RS16355	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AMD22_RS16365	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AMD22_RS16370	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AMD22_RS16375	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AMD22_RS16380	ENOG4105CDY	transcriptional regulatory protein
AMD22_RS16395	ENOG4105C9M	aspartyl-trna synthetase
AMD22_RS16410	ENOG4108ISG	Major Facilitator
AMD22_RS16420	ENOG4105HSS	phospholipase C
AMD22_RS16435	ENOG4105ETT	transcriptional Regulator, LysR family
AMD22_RS16445	ENOG4105C5H	ABC transporter
AMD22_RS16450	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS16465	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS16470	ENOG4107RNH	Outer membrane receptor FepA
AMD22_RS16480	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AMD22_RS16505	ENOG4105GAV	receptor
AMD22_RS16520	ENOG4105C6X	Major Facilitator
AMD22_RS16530	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AMD22_RS16555	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AMD22_RS16560	ENOG4108YZT	Adenosylcobinamide kinase
AMD22_RS16565	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AMD22_RS16570	ENOG4105EFT	decarboxylase
AMD22_RS16575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AMD22_RS16580	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AMD22_RS16595	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS16600	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AMD22_RS16605	ENOG4105E2Y	ABC, transporter
AMD22_RS16610	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AMD22_RS16615	ENOG4105GVF	(ABC) transporter
AMD22_RS16620	ENOG4105CPC	Aldo Keto reductase
AMD22_RS16630	ENOG4107ZSV	Receptor
AMD22_RS16635	ENOG41082IR	Excinuclease ABC C subunit domain protein
AMD22_RS16670	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS16675	ENOG4108K4C	ec 3.1.3.12
AMD22_RS16680	ENOG4105BZP	glycoside hydrolase 15-related
AMD22_RS16685	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AMD22_RS16690	ENOG4105DZG	Dehydrogenase
AMD22_RS16695	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS16700	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AMD22_RS16715	ENOG4105C34	Pseudouridine synthase
AMD22_RS16720	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMD22_RS16730	ENOG4105C4K	Nad synthetase
AMD22_RS16760	ENOG4105CVE	Lytic murein transglycosylase
AMD22_RS16785	ENOG4108X1T	PAAR repeat-containing protein
AMD22_RS16805	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AMD22_RS16810	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AMD22_RS16815	ENOG4107TUY	Histidine kinase
AMD22_RS16820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AMD22_RS16825	ENOG4107QHF	type ii secretion system protein e
AMD22_RS16830	ENOG4107QHF	type ii secretion system protein e
AMD22_RS16835	ENOG4107QHF	type ii secretion system protein e
AMD22_RS16855	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AMD22_RS16860	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AMD22_RS16885	ENOG4105BZU	Histidine kinase
AMD22_RS16890	ENOG4105ETX	regulatoR
AMD22_RS16960	ENOG4105W5Q	DNA repair protein (RadC
AMD22_RS16985	ENOG4105CQZ	Histidine kinase
AMD22_RS16990	ENOG4105CQZ	Histidine kinase
AMD22_RS17125	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AMD22_RS17130	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AMD22_RS17155	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AMD22_RS17170	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS17200	ENOG4105EIB	trna rrna methyltransferase
AMD22_RS17210	ENOG4105CD8	aminopeptidase N
AMD22_RS17260	ENOG4105BZS	acriflavin resistance protein
AMD22_RS17270	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AMD22_RS17275	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AMD22_RS17280	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AMD22_RS17285	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AMD22_RS17290	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AMD22_RS17310	ENOG4105BZU	Histidine kinase
AMD22_RS17325	ENOG4107R11	Transcriptional regulator
AMD22_RS17330	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AMD22_RS17345	ENOG4108UVJ	appr-1-p processing domain protein
AMD22_RS17350	ENOG4107R1Y	fructose-bisphosphate aldolase
AMD22_RS17355	ENOG4105CA9	Pyruvate kinase
AMD22_RS17365	ENOG4105BZA	Phosphoglycerate kinase
AMD22_RS17385	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AMD22_RS17395	ENOG4105EIF	outer membrane protein W
AMD22_RS17400	ENOG4105EIF	outer membrane protein W
AMD22_RS17410	ENOG4107S76	domain protein
AMD22_RS17415	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AMD22_RS17420	ENOG4105E0C	molybdate abc transporter
AMD22_RS17425	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AMD22_RS17460	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AMD22_RS17465	ENOG4105DR5	peptidase
AMD22_RS17475	ENOG4105CNM	Receptor
AMD22_RS17490	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AMD22_RS17495	ENOG4105CK2	sodium dicarboxylate symporter
AMD22_RS17505	ENOG4107QVM	von Willebrand factor, type A
AMD22_RS17525	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AMD22_RS17530	ENOG4105E4G	Type IV pilus
AMD22_RS17555	ENOG4108JQC	penicillin-binding protein 1A
AMD22_RS17575	ENOG4105DU0	nucleoside hydrolase
AMD22_RS17580	ENOG4105CB5	ATP-dependent DNA helicase recG
AMD22_RS17585	ENOG4105KME	endoribonuclease L-psp
AMD22_RS17590	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AMD22_RS17600	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AMD22_RS17605	ENOG4105DSJ	YicC domain protein
AMD22_RS17610	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AMD22_RS17620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AMD22_RS17625	ENOG4105CSA	Coproporphyrinogen iii oxidase
AMD22_RS17640	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AMD22_RS17650	ENOG4107RAQ	aminopeptidase
AMD22_RS17665	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AMD22_RS17670	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AMD22_RS17680	ENOG4105E66	phosphoriboisomerase A
AMD22_RS17690	ENOG41063JG	Transcriptional regulator
AMD22_RS17695	ENOG4105VCQ	rubredoxin
AMD22_RS17700	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AMD22_RS17715	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AMD22_RS17720	ENOG41061ZR	Transcriptional regulator
AMD22_RS17730	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AMD22_RS17760	ENOG4105C8Y	Acetylornithine aminotransferase
AMD22_RS17765	ENOG4105EYW	Ion transport protein
AMD22_RS17780	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AMD22_RS17785	ENOG4105FFC	UPF0187 protein
AMD22_RS17795	ENOG4105DFU	Cell wall formation (By similarity)
AMD22_RS17800	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AMD22_RS17815	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMD22_RS17825	ENOG4105F0N	pyrophosphate phospho-hydrolase
AMD22_RS17840	ENOG4105ECQ	AraC Family Transcriptional Regulator
AMD22_RS17845	ENOG4108M3R	transcriptional activator CadC
AMD22_RS17850	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AMD22_RS17865	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AMD22_RS17870	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AMD22_RS17885	ENOG4105C7B	Threonine dehydratase
AMD22_RS17890	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AMD22_RS17895	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AMD22_RS17900	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AMD22_RS17905	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AMD22_RS17910	ENOG4108MP6	LysR family Transcriptional regulator
AMD22_RS17925	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AMD22_RS17930	ENOG4105DFG	type I secretion outer membrane protein
AMD22_RS17935	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AMD22_RS17940	ENOG4105D1S	lipid A biosynthesis
AMD22_RS17965	ENOG4105C6K	Malic enzyme
AMD22_RS17970	ENOG4105CK2	sodium dicarboxylate symporter
AMD22_RS17980	ENOG4105CQZ	Histidine kinase
AMD22_RS17985	ENOG4105CSH	Transporter
AMD22_RS17995	ENOG4105F04	LysR family Transcriptional regulator
AMD22_RS18000	ENOG4105CPC	Aldo Keto reductase
AMD22_RS18015	ENOG4105WH1	Two component transcriptional regulator luxr family
AMD22_RS18020	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AMD22_RS18025	ENOG4105DHQ	Histidine kinase
AMD22_RS18040	ENOG4105D4T	Citrate transporter
AMD22_RS18045	ENOG4105CHR	reductase
AMD22_RS18050	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS18065	ENOG4107QW3	Sucrose phosphorylase
AMD22_RS18080	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AMD22_RS18100	ENOG4105CNM	Receptor
AMD22_RS18145	ENOG4108RMV	DegV Family
AMD22_RS18150	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AMD22_RS18170	ENOG4105EJG	cellulose synthase
AMD22_RS18175	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AMD22_RS18180	ENOG4107EEX	Cellulose synthase regulator protein
AMD22_RS18185	ENOG4107QZ7	Cellulose synthase catalytic subunit
AMD22_RS18200	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AMD22_RS18255	ENOG4106S9K	Transcriptional regulator
AMD22_RS18265	ENOG4105GVR	general secretion pathway protein D
AMD22_RS18275	ENOG410678M	general secretion pathway protein M
AMD22_RS18280	ENOG41090VX	general secretion pathway protein L
AMD22_RS18285	ENOG4105UV2	general secretion pathway protein K
AMD22_RS18290	ENOG41069G9	General secretion pathway protein J
AMD22_RS18300	ENOG4105WMT	general secretion pathway protein h
AMD22_RS18310	ENOG4105D7Q	type ii secretion system
AMD22_RS18315	ENOG4107QHF	type ii secretion system protein e
AMD22_RS18320	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AMD22_RS18325	ENOG4105EUR	Domain-Containing protein
AMD22_RS18330	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AMD22_RS18335	ENOG4105EUR	Domain-Containing protein
AMD22_RS18345	ENOG4108ETH	Formylglycinamide ribotide synthetase
AMD22_RS18350	ENOG4105T95	Thiol disulfide interChange protein
AMD22_RS18355	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AMD22_RS18370	ENOG4108K5H	permease YjgP YjgQ family protein
AMD22_RS18380	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AMD22_RS18395	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AMD22_RS18400	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS18425	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AMD22_RS18435	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AMD22_RS18440	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AMD22_RS18455	ENOG4105DHJ	ABC, transporter
AMD22_RS18460	ENOG4108SNX	Mammalian cell entry related domain protein
AMD22_RS18475	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AMD22_RS18495	ENOG4107QKV	phosphomannomutase
AMD22_RS18500	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AMD22_RS18510	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AMD22_RS18515	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AMD22_RS18530	ENOG4105BZJ	Electron transfer flavoprotein
AMD22_RS18535	ENOG4105C10	Electron transfer flavoprotein
AMD22_RS18550	ENOG4105IQ5	FAD linked oxidase domain protein
AMD22_RS18565	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AMD22_RS18605	ENOG4105EY8	ABC transporter
AMD22_RS18615	ENOG4105C28	cystathionine
AMD22_RS18640	ENOG4105CZX	twitching motility protein
AMD22_RS18650	ENOG4108RXX	maleylacetoacetate isomerase
AMD22_RS18660	ENOG4105C1J	atp-dependent rna helicase
AMD22_RS18670	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AMD22_RS18675	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AMD22_RS18685	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AMD22_RS18705	ENOG4105NIV	Esterase
AMD22_RS18710	ENOG4107RNH	Outer membrane receptor FepA
AMD22_RS18715	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AMD22_RS18720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AMD22_RS18725	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AMD22_RS18740	ENOG4105DGW	oligopeptidase A
AMD22_RS18790	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AMD22_RS18795	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AMD22_RS18800	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AMD22_RS18805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AMD22_RS18810	ENOG4107RBB	ABC transporter, permease
AMD22_RS18825	ENOG4105BZU	Histidine kinase
AMD22_RS18830	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AMD22_RS18845	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AMD22_RS18850	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AMD22_RS18855	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AMD22_RS18860	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AMD22_RS18865	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AMD22_RS18870	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AMD22_RS18875	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AMD22_RS18880	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AMD22_RS18900	ENOG4107QN2	dihydrolipoyl dehydrogenase
AMD22_RS18910	ENOG4107QSN	dihydrolipoamide acetyltransferase
AMD22_RS18950	ENOG4105D01	(LipO)protein
AMD22_RS18955	ENOG4108UMI	ABC transporter, permease
AMD22_RS18960	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AMD22_RS18965	ENOG4108EHX	EamA-like transporter family
AMD22_RS18970	ENOG4108VPT	UPF0234 protein
AMD22_RS18980	ENOG4105BZU	Histidine kinase
AMD22_RS19000	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AMD22_RS19005	ENOG4107YBY	Hydrolase
AMD22_RS19010	ENOG4105I08	Pseudouridine synthase
AMD22_RS19015	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AMD22_RS19035	ENOG4105BZU	Histidine kinase
AMD22_RS19055	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AMD22_RS19060	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AMD22_RS19065	ENOG4105EW9	transcriptional regulator AsnC family
AMD22_RS19085	ENOG4107RD7	Flagellar Motor Protein, MotA
AMD22_RS19090	ENOG4105ER2	Ompa motb domain protein
AMD22_RS19115	ENOG4105E3A	(ABC) transporter
AMD22_RS19120	ENOG4105DA5	(ABC) transporter
AMD22_RS19125	ENOG4105EEQ	Na H antiporter
AMD22_RS19135	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AMD22_RS19145	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AMD22_RS19155	ENOG4105CBN	LysR family transcriptional regulator
AMD22_RS19165	ENOG4105CPC	Aldo Keto reductase
AMD22_RS19195	ENOG4107QTZ	amino acid
AMD22_RS19205	ENOG4108VAC	response regulator
AMD22_RS19225	ENOG4108Z9Z	response to DNA damage stimulus
AMD22_RS19230	ENOG4105WEF	catalase
AMD22_RS19250	ENOG4105BZU	Histidine kinase
AMD22_RS19265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AMD22_RS19275	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AMD22_RS19280	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AMD22_RS19295	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AMD22_RS19300	ENOG4105CMR	udp-glucose 4-epimerase
AMD22_RS19320	ENOG4105BZ1	(ABC) transporter
AMD22_RS19335	ENOG4105E2A	Dehydrogenase
AMD22_RS19395	ENOG4105CIG	ABC transporter
AMD22_RS19410	ENOG4108UQ8	endoribonuclease L-psp
AMD22_RS19440	ENOG4105C8Q	Methyl-accepting chemotaxis
AMD22_RS19460	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AMD22_RS19520	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AMD22_RS19525	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AMD22_RS19530	ENOG4105D1S	lipid A biosynthesis
AMD22_RS19535	ENOG4108Z7F	N-acetyltransferase
AMD22_RS19580	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AMD22_RS19585	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AMD22_RS19590	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AMD22_RS19595	ENOG4108WZM	domain protein
AMD22_RS19600	ENOG4105C79	DNA protecting protein DprA
AMD22_RS19605	ENOG4108RPN	Protein smg homolog
AMD22_RS19620	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AMD22_RS19625	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AMD22_RS19640	ENOG4107ZQV	short-chain dehydrogenase reductase
AMD22_RS19650	ENOG4105D07	Signal peptide peptidase, SppA
AMD22_RS19655	ENOG4107QI1	Mate efflux family protein
AMD22_RS19675	ENOG4105C25	Primosomal protein n'
AMD22_RS19680	ENOG4108TGY	Glutathione S-transferase
AMD22_RS19700	ENOG4105EN6	Membrane
AMD22_RS19705	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AMD22_RS19710	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AMD22_RS19715	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AMD22_RS19720	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AMD22_RS19725	ENOG4105CAK	Cell division ATP-binding protein ftsE
AMD22_RS19730	ENOG4105C1J	atp-dependent rna helicase
AMD22_RS19740	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AMD22_RS19745	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AMD22_RS19750	ENOG4105ETT	transcriptional Regulator, LysR family
AMD22_RS19760	ENOG4105E9K	Isocitrate dehydrogenase
AMD22_RS19775	ENOG4105FB9	CRISPR-associated protein
AMD22_RS19795	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AMD22_RS19800	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AMD22_RS19810	ENOG4109066	lysm domain bon superfamily protein
AMD22_RS19815	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AMD22_RS19820	ENOG4105CH2	amidohydrolase
AMD22_RS19825	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AMD22_RS19830	ENOG4105BZS	acriflavin resistance protein
AMD22_RS19840	ENOG4105E32	cytoplasmic protein
AMD22_RS19880	ENOG4108UQS	dipeptidase
AMD22_RS19885	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AMD22_RS19895	ENOG4105DTQ	mandelate racemase muconate lactonizing
AMD22_RS19905	ENOG4105D5Q	Arginine ornithine antiporter
AMD22_RS19920	ENOG4108Z12	YiaAB two helix domain-containing protein
AMD22_RS19930	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AMD22_RS19935	ENOG4107ZVW	dihydroneopterin aldolase
AMD22_RS19940	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AMD22_RS19950	ENOG4105KTH	gatB Yqey
AMD22_RS19955	ENOG4107S2Z	UPF0761 membrane protein
AMD22_RS19960	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AMD22_RS19965	ENOG4105DHU	Bile acid
AMD22_RS19975	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AMD22_RS20000	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AMD22_RS20005	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AMD22_RS20015	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AMD22_RS20025	ENOG4105C26	Dehydrogenase
AMD22_RS20060	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AMD22_RS20065	ENOG4105DR5	peptidase
AMD22_RS20070	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AMD22_RS20080	ENOG4105EYM	Major Facilitator superfamily
AMD22_RS20085	ENOG4105CGK	Exodeoxyribonuclease III
AMD22_RS20090	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AMD22_RS20100	ENOG4107QJE	Chromosome Partitioning Protein
AMD22_RS20105	ENOG4105FA0	parb-like partition protein
AMD22_RS20120	ENOG4105CKK	Glycosyl transferase, family 2
AMD22_RS20140	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AMD22_RS20145	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AMD22_RS20150	ENOG4105W5Q	DNA repair protein (RadC
AMD22_RS20155	ENOG4105C75	arginyL-tRNA synthetase
AMD22_RS20170	ENOG4105EMU	Dehydrogenase
AMD22_RS20175	ENOG4105EXC	Acyl-transferase
AMD22_RS20185	ENOG4105CEY	Amp-dependent synthetase and ligase
AMD22_RS20195	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AMD22_RS20200	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AMD22_RS20230	ENOG4108YZA	Nitrogen regulatory protein pii
AMD22_RS20235	ENOG4105W0Z	cytoplasmic protein
AMD22_RS20240	ENOG4105C0P	Mg chelatase subunit ChlI
AMD22_RS20255	ENOG41066DG	(EAL) domain protein
AMD22_RS20270	ENOG4105EJ2	Transcriptional regulator
AMD22_RS20290	ENOG4105E0Y	RtcB Protein
AMD22_RS20330	ENOG4105ECP	epimerase
AMD22_RS20335	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AMD22_RS20340	ENOG4105DHQ	Histidine kinase
AMD22_RS20360	ENOG4105C0H	protease
AMD22_RS20380	ENOG4105DSF	transport protein
AMD22_RS20385	ENOG4107URF	beta-phospho-glucomutase
AMD22_RS20390	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AMD22_RS20405	ENOG4107VGR	Catalase
AMD22_RS20420	ENOG4108S01	response regulator
AMD22_RS20425	ENOG4108ZGX	Histidine kinase
AMD22_RS20430	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AMD22_RS20435	ENOG4105C19	ABC transporter
AMD22_RS20460	ENOG4105FDR	Membrane
AMD22_RS20475	ENOG4108NNI	Beta-lactamase domain-containing protein
AMD22_RS20480	ENOG4105C31	Tryptophanyl-tRNA synthetase
AMD22_RS20485	ENOG4105VDW	Csbd family
AMD22_RS20545	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AMD22_RS20570	ENOG4105EB3	Histidine kinase
AMD22_RS20575	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AMD22_RS20585	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AMD22_RS20605	ENOG4105DVT	helicase
AMD22_RS20620	ENOG4105E2X	shikimate dehydrogenase
AMD22_RS20630	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AMD22_RS20650	ENOG4105D52	delta-aminolevulinic acid dehydratase
AMD22_RS20680	ENOG4105CYM	Glutathione S-transferase
AMD22_RS20705	ENOG4105QV4	Tryptophan halogenase
AMD22_RS20720	ENOG4108IUW	ABC transporter
AMD22_RS20730	ENOG4105VZ8	Transcriptional regulator
AMD22_RS20750	ENOG4105PGM	cation diffusion facilitator family transporter
AMD22_RS20760	ENOG4105E0K	tonB-dependent siderophore receptor
AMD22_RS20770	ENOG4105ECQ	AraC Family Transcriptional Regulator
AMD22_RS20775	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AMD22_RS20780	ENOG4105DA5	(ABC) transporter
AMD22_RS20785	ENOG4105E3A	(ABC) transporter
AMD22_RS20795	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AMD22_RS20825	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AMD22_RS20830	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AMD22_RS20840	ENOG4105CD5	CoA-binding domain protein
AMD22_RS20845	ENOG4105CJW	magnesium transporter
AMD22_RS20860	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AMD22_RS20865	ENOG4105BZP	glycoside hydrolase 15-related
AMD22_RS20885	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AMD22_RS20895	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AMD22_RS20950	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AMD22_RS20955	ENOG4105E9Q	Acyl-transferase
AMD22_RS20965	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AMD22_RS20990	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AMD22_RS21005	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AMD22_RS21010	ENOG4105C2M	dna polymerase I
AMD22_RS21040	ENOG4105D9P	serine threonine protein kinase
AMD22_RS21045	ENOG4108ZF3	Phosphatase
AMD22_RS21080	ENOG4105CS6	Rhs element vgr protein
AMD22_RS21120	ENOG4105D6F	Phosphatase
AMD22_RS21150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AMD22_RS21175	ENOG4108WC9	type VI secretion system effector, hcp1 family
AMD22_RS21205	ENOG4105C4R	Atp-dependent dna helicase
AMD22_RS21220	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AMD22_RS21225	ENOG4108KB2	LysR family Transcriptional regulator
AMD22_RS21230	ENOG4105JSC	dimethylmenaquinone methyltransferase
AMD22_RS21240	ENOG4105KHM	amidohydrolase 2
AMD22_RS21260	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AMD22_RS21280	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AMD22_RS21285	ENOG4105DGI	Alkaline phosphatase
AMD22_RS21315	ENOG4105CGK	Exodeoxyribonuclease III
AMD22_RS21320	ENOG4105E2R	ROK family
AMD22_RS21330	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AMD22_RS21340	ENOG4107QN1	sodium solute
AMD22_RS21345	ENOG41062QD	Membrane
AMD22_RS21355	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AMD22_RS21385	ENOG4105DSG	hydrolase family 43
AMD22_RS21405	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AMD22_RS21410	ENOG4105ERH	Fumarylacetoacetate hydrolase
AMD22_RS21415	ENOG4105DIA	mandelate racemase muconate lactonizing
AMD22_RS21425	ENOG4105QJH	Domain of unknown function (DUF718)
AMD22_RS21430	ENOG4105EDR	glucose galactose transporter
AMD22_RS21435	ENOG4108K2P	TRANSCRIPTIONal
AMD22_RS21440	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AMD22_RS21445	ENOG4105BZU	Histidine kinase
AMD22_RS21460	ENOG4105E2V	Glycosyltransferase 36
AMD22_RS21465	ENOG4105CT4	transporter
AMD22_RS21470	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AMD22_RS21495	ENOG4105MA0	exported protein
AMD22_RS21500	ENOG4105CFU	surface antigen
AMD22_RS21540	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AMD22_RS21545	ENOG4107QHF	type ii secretion system protein e
AMD22_RS21555	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AMD22_RS21565	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AMD22_RS21570	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AMD22_RS21585	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AMD22_RS21605	ENOG4105DH7	May be involved in recombination (By similarity)
AMD22_RS21610	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AMD22_RS21615	ENOG4105C93	Xylose Isomerase
AMD22_RS21620	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS21625	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AMD22_RS21635	ENOG4105CXK	mandelate racemase muconate lactonizing
AMD22_RS21650	ENOG4105DEI	Mannitol dehydrogenase
AMD22_RS21730	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
AMD22_RS21735	ENOG4105CNT	hydrolase family 2
AMD22_RS21740	ENOG4105D2H	Uronic isomerase
AMD22_RS21775	ENOG4105CT4	transporter
AMD22_RS21780	ENOG4105DT9	hydrolase family 43
AMD22_RS21820	ENOG4105E55	glycerol-3-phosphate acyltransferase
AMD22_RS21830	ENOG4105ETE	Transcriptional regulator (LacI family
AMD22_RS21850	ENOG4105QV4	Tryptophan halogenase
AMD22_RS21855	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AMD22_RS21860	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AMD22_RS21865	ENOG4108YXG	UPF0502 protein
AMD22_RS21880	ENOG4105C4R	Atp-dependent dna helicase
AMD22_RS21885	ENOG4107104	thymidine kinase
AMD22_RS21890	ENOG4105BZU	Histidine kinase
AMD22_RS21895	ENOG4105DJ9	glucan biosynthesis protein
AMD22_RS21905	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AMD22_RS21940	ENOG4105DKK	Benzoate
AMD22_RS21960	ENOG4105DSB	aldose 1-epimerase
AMD22_RS21970	ENOG4105K5B	UPF0225 protein
AMD22_RS21975	ENOG4105EJ9	Membrane
AMD22_RS21995	ENOG4105EUJ	GTP cyclohydrolase i
AMD22_RS22005	ENOG4105ZQC	membrane protein AaeX
AMD22_RS22010	ENOG4105Y49	secretion protein, HlyD family
AMD22_RS22020	ENOG4105DR8	Membrane
AMD22_RS22025	ENOG4105CSH	Transporter
AMD22_RS22035	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AMD22_RS22120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AMD22_RS22160	ENOG4107QKA	exodeoxyribonuclease V beta
AMD22_RS22165	ENOG4105DSY	exodeoxyribonuclease V, gamma
AMD22_RS22180	ENOG4105DHJ	ABC, transporter
AMD22_RS22185	ENOG4105CY3	ABC transporter, permease
AMD22_RS22190	ENOG4107PE3	Mammalian cell entry related domain protein
AMD22_RS22205	ENOG410903C	(LipO)protein
AMD22_RS22215	ENOG4108V06	Glutathione peroxidase
AMD22_RS22225	ENOG4107QSV	RmuC domain protein
AMD22_RS22230	ENOG4105CIS	alcohol dehydrogenase
AMD22_RS22245	ENOG4108TGY	Glutathione S-transferase
AMD22_RS22255	ENOG4105CUB	amino acid
AMD22_RS22260	ENOG4105CWX	Alpha-1,2-mannosidase
AMD22_RS22265	ENOG4105NRM	Membrane
AMD22_RS22270	ENOG4105BZU	Histidine kinase
AMD22_RS22275	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AMD22_RS22280	ENOG4105BZW	Glycerate kinase
AMD22_RS22285	ENOG4105CSP	Major Facilitator Superfamily
AMD22_RS22300	ENOG4105DR4	Methyltransferase
AMD22_RS22305	ENOG4105DU1	integral membrane protein, terc
AMD22_RS22315	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AMD22_RS22330	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AMD22_RS22335	ENOG4108ZJ4	polysaccharide deacetylase
AMD22_RS22345	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AMD22_RS22350	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AMD22_RS22375	ENOG4108C33	Resolvase
AMD22_RS22730	ENOG4105NI8	Cytosine-specific methyltransferase
AMD22_RS23100	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS23105	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS23110	ENOG4105C1G	acyl-Coa dehydrogenase
AMD22_RS23335	ENOG4108KU3	Integrase
AMD22_RS23780	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
AMD22_RS23800	ENOG4105HSS	phospholipase C
AMD22_RS23935	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AMD22_RS24580	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AMD22_RS24815	ENOG4105C2F	Histidine kinase
AMD22_RS24825	ENOG4107QKV	phosphomannomutase