locus-tag	class	description
FPK90_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPK90_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPK90_RS00025	COG0187	DNA topoisomerase II activity
FPK90_RS00035	COG0501	Belongs to the peptidase M48B family
FPK90_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FPK90_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPK90_RS00120	COG0793	Belongs to the peptidase S41A family
FPK90_RS00125	COG4942	peptidase
FPK90_RS00135	COG2234	aminopeptidase activity
FPK90_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FPK90_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FPK90_RS00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FPK90_RS00170	COG1064	alcohol dehydrogenase
FPK90_RS00180	COG0493	'glutamate synthase
FPK90_RS00185	COG0069	glutamate synthase activity
FPK90_RS00185	COG0067	glutamate synthase
FPK90_RS00185	COG0070	glutamate synthase
FPK90_RS00235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FPK90_RS00250	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FPK90_RS00255	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS00255	COG0297	glycogen (starch) synthase activity
FPK90_RS00275	COG0367	asparagine synthase
FPK90_RS00305	COG1132	(ABC) transporter
FPK90_RS00335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FPK90_RS00430	COG1205	dead DEAH box helicase
FPK90_RS00430	COG1111	helicase
FPK90_RS00435	COG1272	protein, Hemolysin III
FPK90_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS00485	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPK90_RS00495	COG3237	CsbD-like
FPK90_RS00540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPK90_RS00550	COG0477	Major facilitator Superfamily
FPK90_RS00590	COG0714	Associated with various cellular activities
FPK90_RS00620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FPK90_RS00630	COG4772	TonB-dependent receptor
FPK90_RS00640	COG0662	Cupin 2, conserved barrel domain protein
FPK90_RS00645	COG1012	belongs to the aldehyde dehydrogenase family
FPK90_RS00670	COG1304	FMN binding
FPK90_RS00685	COG4585	Histidine kinase
FPK90_RS00690	COG2197	response regulator
FPK90_RS00710	COG3710	Transcriptional regulator
FPK90_RS00715	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FPK90_RS00750	COG2131	deaminase
FPK90_RS00800	COG0366	Alpha amylase catalytic
FPK90_RS00805	COG0366	Alpha amylase catalytic
FPK90_RS00810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FPK90_RS00830	COG2755	lipolytic protein G-D-S-L family
FPK90_RS00830	COG0657	acetylesterase activity
FPK90_RS00840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPK90_RS00855	COG3507	Belongs to the glycosyl hydrolase 43 family
FPK90_RS00860	COG1609	Transcriptional regulator
FPK90_RS00880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FPK90_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS00895	COG2755	lipolytic protein G-D-S-L family
FPK90_RS00910	COG3186	Phenylalanine-4-hydroxylase
FPK90_RS00915	COG1522	sequence-specific DNA binding
FPK90_RS00925	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPK90_RS00935	COG1119	ATPase activity
FPK90_RS00950	COG1125	glycine betaine transport
FPK90_RS00965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FPK90_RS00985	COG3550	peptidyl-serine autophosphorylation
FPK90_RS00990	COG1396	sequence-specific DNA binding
FPK90_RS01015	COG0489	protein tyrosine kinase activity
FPK90_RS01020	COG2062	phosphohistidine phosphatase, SixA
FPK90_RS01030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPK90_RS01075	COG1968	undecaprenyl-diphosphatase activity
FPK90_RS01085	COG0174	glutamine synthetase
FPK90_RS01090	COG0347	Belongs to the P(II) protein family
FPK90_RS01095	COG0004	ammonium transporteR
FPK90_RS01100	COG3852	Histidine kinase
FPK90_RS01105	COG2204	response regulator
FPK90_RS01110	COG2032	superoxide dismutase activity
FPK90_RS01115	COG2032	superoxide dismutase activity
FPK90_RS01125	COG0346	lactoylglutathione lyase activity
FPK90_RS01135	COG0183	Belongs to the thiolase family
FPK90_RS01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPK90_RS01175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FPK90_RS01180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FPK90_RS01235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPK90_RS01240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPK90_RS01245	COG4786	Flagellar basal body rod
FPK90_RS01250	COG4786	Flagellar basal body rod
FPK90_RS01260	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FPK90_RS01265	COG1706	bacterial-type flagellum-dependent cell motility
FPK90_RS01280	COG1677	Flagellar hook-basal body complex protein FliE
FPK90_RS01300	COG1157	protein secretion by the type III secretion system
FPK90_RS01315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FPK90_RS01350	COG0028	Belongs to the TPP enzyme family
FPK90_RS01355	COG2205	protein histidine kinase activity
FPK90_RS01380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FPK90_RS01395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPK90_RS01405	COG0596	Alpha beta hydrolase
FPK90_RS01410	COG0727	PFAM Uncharacterised protein family (UPF0153)
FPK90_RS01415	COG0318	PFAM AMP-dependent synthetase and ligase
FPK90_RS01420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPK90_RS01445	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPK90_RS01455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FPK90_RS01465	COG0564	pseudouridine synthase activity
FPK90_RS01485	COG1446	asparaginase
FPK90_RS01490	COG0339	signal peptide processing
FPK90_RS01525	COG0475	glutathione-regulated potassium exporter activity
FPK90_RS01530	COG0583	DNA-binding transcription factor activity
FPK90_RS01535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPK90_RS01540	COG2224	Isocitrate lyase
FPK90_RS01570	COG4770	biotin carboxylase activity
FPK90_RS01575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPK90_RS01580	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS01635	COG0523	cobalamin synthesis protein
FPK90_RS01645	COG0697	spore germination
FPK90_RS01655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FPK90_RS01660	COG1846	Transcriptional regulator
FPK90_RS01665	COG1764	response to oxidative stress
FPK90_RS01695	COG2130	NADP-dependent
FPK90_RS01710	COG1187	pseudouridine synthase activity
FPK90_RS01725	COG1643	Atp-dependent helicase
FPK90_RS01735	COG4807	Protein conserved in bacteria
FPK90_RS01740	COG2351	hydroxyisourate hydrolase activity
FPK90_RS01745	COG2072	flavoprotein involved in K transport
FPK90_RS01765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPK90_RS01800	COG1957	nucleoside hydrolase
FPK90_RS01810	COG2252	PERMEase
FPK90_RS01835	COG0084	hydrolase, TatD family'
FPK90_RS01850	COG0583	DNA-binding transcription factor activity
FPK90_RS01855	COG2814	Major facilitator Superfamily
FPK90_RS01870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FPK90_RS01875	COG1902	pentaerythritol trinitrate reductase activity
FPK90_RS01895	COG0745	RESPONSE REGULATOR receiver
FPK90_RS01900	COG2205	protein histidine kinase activity
FPK90_RS01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS01930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPK90_RS01935	COG0583	DNA-binding transcription factor activity
FPK90_RS01970	COG0702	epimerase
FPK90_RS01975	COG1733	regulation of RNA biosynthetic process
FPK90_RS02055	COG0129	dihydroxy-acid dehydratase activity
FPK90_RS02070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FPK90_RS02130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FPK90_RS02135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FPK90_RS02160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FPK90_RS02165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPK90_RS02175	COG3485	protocatechuate 3,4-dioxygenase
FPK90_RS02180	COG3485	protocatechuate 3,4-dioxygenase
FPK90_RS02190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPK90_RS02195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FPK90_RS02210	COG1414	Transcriptional regulator
FPK90_RS02220	COG0657	acetylesterase activity
FPK90_RS02230	COG0445	tRNA wobble uridine modification
FPK90_RS02240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPK90_RS02270	COG2267	carboxylic ester hydrolase activity
FPK90_RS02280	COG0156	8-amino-7-oxononanoate synthase activity
FPK90_RS02285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FPK90_RS02290	COG1040	competence protein
FPK90_RS02295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FPK90_RS02385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPK90_RS02470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FPK90_RS02480	COG2354	Protein conserved in bacteria
FPK90_RS02490	COG0297	glycogen (starch) synthase activity
FPK90_RS02495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FPK90_RS02500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FPK90_RS02525	COG0702	epimerase
FPK90_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS02555	COG0513	Belongs to the DEAD box helicase family
FPK90_RS02560	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPK90_RS02575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPK90_RS02585	COG3483	tryptophan 2,3-dioxygenase activity
FPK90_RS02590	COG3104	oligopeptide transport
FPK90_RS02610	COG2852	Protein conserved in bacteria
FPK90_RS02615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FPK90_RS02635	COG1320	monovalent cation:proton antiporter activity
FPK90_RS02640	COG2212	antiporter activity
FPK90_RS02650	COG0651	ATP synthesis coupled electron transport
FPK90_RS02655	COG1006	Multisubunit Na H antiporter MnhC subunit
FPK90_RS02660	COG2111	Na H antiporter
FPK90_RS02660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPK90_RS02685	COG3179	chitinase
FPK90_RS02705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FPK90_RS02710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FPK90_RS02725	COG0456	acetyltransferase
FPK90_RS02730	COG1597	lipid kinase activity
FPK90_RS02760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FPK90_RS02765	COG0134	indole-3-glycerol-phosphate synthase activity
FPK90_RS02775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPK90_RS02780	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPK90_RS02790	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FPK90_RS02800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FPK90_RS02815	COG1051	belongs to the nudix hydrolase family
FPK90_RS02855	COG0316	Belongs to the HesB IscA family
FPK90_RS02875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FPK90_RS02890	COG2814	Major facilitator Superfamily
FPK90_RS02900	COG2814	Major facilitator Superfamily
FPK90_RS02905	COG1289	transmembrane transporter activity
FPK90_RS02915	COG0151	Belongs to the GarS family
FPK90_RS02925	COG0138	bifunctional purine biosynthesis protein purh
FPK90_RS02930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPK90_RS02935	COG2267	carboxylic ester hydrolase activity
FPK90_RS02940	COG2453	phosphatase
FPK90_RS02940	COG0671	phosphoesterase, PA-phosphatase related
FPK90_RS02965	COG4589	Belongs to the CDS family
FPK90_RS02970	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FPK90_RS03000	COG2264	protein methyltransferase activity
FPK90_RS03025	COG0439	Biotin carboxylase
FPK90_RS03035	COG0511	ligase activity, forming carbon-carbon bonds
FPK90_RS03040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FPK90_RS03050	COG1324	tolerance protein
FPK90_RS03080	COG0300	oxidoreductase activity
FPK90_RS03085	COG2356	endonuclease I
FPK90_RS03100	COG0459	protein refolding
FPK90_RS03115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FPK90_RS03130	COG3386	PFAM SMP-30 Gluconolaconase
FPK90_RS03140	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FPK90_RS03145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FPK90_RS03165	COG0778	Nitroreductase
FPK90_RS03170	COG2353	YceI-like domain
FPK90_RS03200	COG3052	prosthetic group binding
FPK90_RS03235	COG1802	Transcriptional regulator
FPK90_RS03365	COG4221	oxidoreductase activity
FPK90_RS03380	COG4221	oxidoreductase activity
FPK90_RS03390	COG0435	Glutathione S-transferase
FPK90_RS03410	COG2409	Drug exporters of the RND superfamily
FPK90_RS03420	COG1506	peptidase
FPK90_RS03420	COG0823	Involved in the tonB-independent uptake of proteins
FPK90_RS03460	COG0697	spore germination
FPK90_RS03475	COG1113	amino acid transport
FPK90_RS03495	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FPK90_RS03540	COG5001	Diguanylate cyclase
FPK90_RS03545	COG0840	transmembrane signaling receptor activity
FPK90_RS03550	COG5297	Belongs to the glycosyl hydrolase family 6
FPK90_RS03550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FPK90_RS03555	COG0659	secondary active sulfate transmembrane transporter activity
FPK90_RS03585	COG2943	transferase activity, transferring hexosyl groups
FPK90_RS03595	COG3275	phosphorelay sensor kinase activity
FPK90_RS03605	COG0181	hydroxymethylbilane synthase activity
FPK90_RS03635	COG1505	serine-type exopeptidase activity
FPK90_RS03645	COG0436	Aminotransferase
FPK90_RS03655	COG2832	Protein of unknown function (DUF454)
FPK90_RS03665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FPK90_RS03675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FPK90_RS03680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FPK90_RS03685	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FPK90_RS03710	COG2226	methyltransferase
FPK90_RS03715	COG3300	MHYT domain
FPK90_RS03715	COG5001	Diguanylate cyclase
FPK90_RS03720	COG0308	aminopeptidase N
FPK90_RS03770	COG3284	Transcriptional regulator
FPK90_RS03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPK90_RS03780	COG1077	Cell shape determining protein MreB Mrl
FPK90_RS03785	COG1792	Involved in formation and maintenance of cell shape
FPK90_RS03800	COG0772	Belongs to the SEDS family
FPK90_RS03810	COG2951	lytic endotransglycosylase activity
FPK90_RS03815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FPK90_RS03825	COG1686	Belongs to the peptidase S11 family
FPK90_RS03835	COG2921	Belongs to the UPF0250 family
FPK90_RS03840	COG0321	lipoyl(octanoyl) transferase activity
FPK90_RS03845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FPK90_RS03860	COG0583	DNA-binding transcription factor activity
FPK90_RS03870	COG1056	cytidyltransferase-related domain
FPK90_RS03870	COG1051	belongs to the nudix hydrolase family
FPK90_RS03905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPK90_RS03910	COG0673	inositol 2-dehydrogenase activity
FPK90_RS03915	COG2823	Periplasmic or secreted lipoprotein
FPK90_RS03920	COG4251	negative regulation of phosphorylation
FPK90_RS03925	COG0784	Response regulator, receiver
FPK90_RS03930	COG4191	Histidine kinase
FPK90_RS03935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FPK90_RS03995	COG1459	type II secretion system
FPK90_RS04015	COG4795	General secretion pathway protein
FPK90_RS04045	COG3250	beta-galactosidase activity
FPK90_RS04060	COG2188	Transcriptional regulator
FPK90_RS04070	COG1609	Transcriptional regulator
FPK90_RS04075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPK90_RS04080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPK90_RS04090	COG0617	tRNA 3'-terminal CCA addition
FPK90_RS04095	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FPK90_RS04100	COG1012	belongs to the aldehyde dehydrogenase family
FPK90_RS04105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPK90_RS04120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FPK90_RS04135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FPK90_RS04140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FPK90_RS04160	COG2205	protein histidine kinase activity
FPK90_RS04190	COG3791	Glutathione-dependent formaldehyde-activating
FPK90_RS04205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPK90_RS04225	COG0488	(ABC) transporter
FPK90_RS04235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FPK90_RS04240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FPK90_RS04250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPK90_RS04250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPK90_RS04270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FPK90_RS04275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPK90_RS04280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FPK90_RS04305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FPK90_RS04310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FPK90_RS04315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FPK90_RS04320	COG2205	protein histidine kinase activity
FPK90_RS04325	COG0745	RESPONSE REGULATOR receiver
FPK90_RS04340	COG0277	FAD linked oxidase domain protein
FPK90_RS04350	COG0792	nuclease activity
FPK90_RS04390	COG0275	rRNA processing
FPK90_RS04395	COG3116	cell division
FPK90_RS04405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPK90_RS04410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPK90_RS04415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPK90_RS04425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPK90_RS04430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPK90_RS04435	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPK90_RS04440	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FPK90_RS04455	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FPK90_RS04465	COG0739	heme binding
FPK90_RS04470	COG0653	protein targeting
FPK90_RS04475	COG0494	nUDIX hydrolase
FPK90_RS04485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FPK90_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS04500	COG3321	synthase
FPK90_RS04500	COG0604	alcohol dehydrogenase
FPK90_RS04535	COG0366	Alpha amylase catalytic
FPK90_RS04560	COG2226	methyltransferase
FPK90_RS04565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FPK90_RS04575	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FPK90_RS04615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPK90_RS04625	COG4106	trans-aconitate 2-methyltransferase activity
FPK90_RS04630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPK90_RS04640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPK90_RS04645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPK90_RS04655	COG0667	Aldo Keto reductase
FPK90_RS04665	COG4771	TonB-dependent receptor
FPK90_RS04685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPK90_RS04690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FPK90_RS04700	COG2175	clavaminate synthase activity
FPK90_RS04710	COG4181	ATPase activity
FPK90_RS04725	COG0642	Histidine kinase
FPK90_RS04735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FPK90_RS04755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FPK90_RS04760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FPK90_RS04775	COG3829	transcription factor binding
FPK90_RS04785	COG1116	anion transmembrane transporter activity
FPK90_RS04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPK90_RS04800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK90_RS04805	COG0431	NADPH-dependent FMN reductase
FPK90_RS04830	COG0747	negative chemotaxis
FPK90_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPK90_RS04850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPK90_RS04855	COG2967	ApaG domain
FPK90_RS04860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPK90_RS04865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FPK90_RS04870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPK90_RS04875	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FPK90_RS04880	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPK90_RS04885	COG2096	Adenosyltransferase
FPK90_RS04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPK90_RS04905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPK90_RS04935	COG3384	dioxygenase
FPK90_RS04940	COG0583	DNA-binding transcription factor activity
FPK90_RS04955	COG1024	Enoyl-CoA hydratase
FPK90_RS04975	COG3386	PFAM SMP-30 Gluconolaconase
FPK90_RS04990	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FPK90_RS05010	COG0697	spore germination
FPK90_RS05020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPK90_RS05045	COG2197	response regulator
FPK90_RS05055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPK90_RS05065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPK90_RS05070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FPK90_RS05080	COG0583	DNA-binding transcription factor activity
FPK90_RS05085	COG3634	alkyl hydroperoxide reductase activity
FPK90_RS05095	COG2890	protein-(glutamine-N5) methyltransferase activity
FPK90_RS05115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPK90_RS05115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPK90_RS05145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FPK90_RS05170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FPK90_RS05185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPK90_RS05190	COG1404	Belongs to the peptidase S8 family
FPK90_RS05195	COG1404	Belongs to the peptidase S8 family
FPK90_RS05200	COG1404	Belongs to the peptidase S8 family
FPK90_RS05205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPK90_RS05230	COG1295	ribonuclease BN
FPK90_RS05235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPK90_RS05240	COG1254	Belongs to the acylphosphatase family
FPK90_RS05255	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPK90_RS05265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FPK90_RS05270	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FPK90_RS05280	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FPK90_RS05285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FPK90_RS05295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPK90_RS05300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FPK90_RS05305	COG0193	aminoacyl-tRNA hydrolase activity
FPK90_RS05310	COG0012	GTP binding
FPK90_RS05330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPK90_RS05345	COG0250	Participates in transcription elongation, termination and antitermination
FPK90_RS05350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FPK90_RS05355	COG0081	regulation of translation
FPK90_RS05360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FPK90_RS05365	COG0222	ribosome binding
FPK90_RS05370	COG0085	RNA polymerase activity
FPK90_RS05375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FPK90_RS05380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FPK90_RS05385	COG0049	tRNA binding
FPK90_RS05390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPK90_RS05395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPK90_RS05400	COG0051	transcription antitermination factor activity, RNA binding
FPK90_RS05405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FPK90_RS05410	COG0088	Forms part of the polypeptide exit tunnel
FPK90_RS05415	COG0089	rRNA binding
FPK90_RS05420	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FPK90_RS05425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FPK90_RS05435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FPK90_RS05440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FPK90_RS05445	COG0255	Belongs to the universal ribosomal protein uL29 family
FPK90_RS05450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FPK90_RS05460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FPK90_RS05465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FPK90_RS05475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FPK90_RS05480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FPK90_RS05485	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FPK90_RS05495	COG1841	ribosomal large subunit assembly
FPK90_RS05500	COG0200	Binds to the 23S rRNA
FPK90_RS05505	COG0201	protein transport
FPK90_RS05530	COG0203	ribosomal protein L17
FPK90_RS05535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FPK90_RS05555	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FPK90_RS05565	COG0154	amidase activity
FPK90_RS05575	COG1217	gtp-binding protein TYPA
FPK90_RS05580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FPK90_RS05585	COG0039	L-malate dehydrogenase activity
FPK90_RS05590	COG0625	glutathione transferase activity
FPK90_RS05610	COG1902	pentaerythritol trinitrate reductase activity
FPK90_RS05610	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPK90_RS05615	COG0604	alcohol dehydrogenase
FPK90_RS05645	COG0156	8-amino-7-oxononanoate synthase activity
FPK90_RS05650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FPK90_RS05655	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FPK90_RS05660	COG4208	sulfate ABC transporter
FPK90_RS05665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FPK90_RS05675	COG1063	alcohol dehydrogenase
FPK90_RS05705	COG0406	alpha-ribazole phosphatase activity
FPK90_RS05710	COG0285	dihydrofolate synthase activity
FPK90_RS05730	COG2833	Protein of unknown function (DUF455)
FPK90_RS05750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPK90_RS05755	COG0671	phosphoesterase, PA-phosphatase related
FPK90_RS05760	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS05770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FPK90_RS05785	COG4783	chaperone-mediated protein folding
FPK90_RS05800	COG0473	3-isopropylmalate dehydrogenase activity
FPK90_RS06060	COG4695	Portal protein
FPK90_RS06120	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPK90_RS06130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FPK90_RS06160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPK90_RS06170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK90_RS06180	COG0328	RNA-DNA hybrid ribonuclease activity
FPK90_RS06185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPK90_RS06190	COG0631	protein serine/threonine phosphatase activity
FPK90_RS06205	COG0859	PFAM glycosyl transferase family 9
FPK90_RS06210	COG3642	lipopolysaccharide core region biosynthetic process
FPK90_RS06215	COG1234	tRNA 3'-trailer cleavage
FPK90_RS06220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FPK90_RS06230	COG0315	cyclic pyranopterin monophosphate synthase activity
FPK90_RS06235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FPK90_RS06240	COG0314	molybdopterin synthase activity
FPK90_RS06260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FPK90_RS06265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FPK90_RS06270	COG0537	adenosine 5'-monophosphoramidase activity
FPK90_RS06290	COG0714	Associated with various cellular activities
FPK90_RS06310	COG0424	maF-like protein
FPK90_RS06315	COG1399	metal-binding, possibly nucleic acid-binding protein
FPK90_RS06320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FPK90_RS06325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPK90_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS06355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPK90_RS06360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPK90_RS06405	COG3829	transcription factor binding
FPK90_RS06425	COG3609	addiction module antidote protein, CC2985 family
FPK90_RS06460	COG2373	Large extracellular alpha-helical protein
FPK90_RS06480	COG4953	penicillin-binding protein 1C
FPK90_RS06490	COG0678	peroxiredoxin activity
FPK90_RS06510	COG0330	HflC and HflK could
FPK90_RS06515	COG0330	HflC and HflK could
FPK90_RS06525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FPK90_RS06530	COG0308	aminopeptidase N
FPK90_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS06540	COG1309	transcriptional regulator
FPK90_RS06570	COG0732	type I restriction modification DNA specificity domain
FPK90_RS06605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FPK90_RS06615	COG3387	PFAM Glycoside hydrolase 15-related
FPK90_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS06630	COG3537	Alpha-1,2-mannosidase
FPK90_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS06655	COG0492	ferredoxin-NADP+ reductase activity
FPK90_RS06680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FPK90_RS06685	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FPK90_RS06690	COG2080	2 iron, 2 sulfur cluster binding
FPK90_RS06725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FPK90_RS06740	COG0587	DNA-directed DNA polymerase activity
FPK90_RS06760	COG1297	OPT oligopeptide transporter protein
FPK90_RS06775	COG0823	Involved in the tonB-independent uptake of proteins
FPK90_RS06775	COG1506	peptidase
FPK90_RS06795	COG1917	Cupin 2, conserved barrel domain protein
FPK90_RS06795	COG2207	Transcriptional regulator
FPK90_RS06815	COG0753	catalase activity
FPK90_RS06820	COG0656	L-ascorbic acid biosynthetic process
FPK90_RS06830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPK90_RS06830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPK90_RS06835	COG2814	Major facilitator Superfamily
FPK90_RS06850	COG2194	sulfuric ester hydrolase activity
FPK90_RS06865	COG0745	RESPONSE REGULATOR receiver
FPK90_RS06870	COG0642	Histidine kinase
FPK90_RS06880	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FPK90_RS06885	COG2894	cell division
FPK90_RS06890	COG0850	regulation of cytokinetic process
FPK90_RS06905	COG4585	Histidine kinase
FPK90_RS06910	COG2197	response regulator
FPK90_RS06925	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPK90_RS06960	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FPK90_RS06970	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FPK90_RS06990	COG1946	Acyl-CoA thioesterase
FPK90_RS07005	COG0824	Thioesterase
FPK90_RS07010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPK90_RS07015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPK90_RS07020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FPK90_RS07025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FPK90_RS07030	COG0268	Binds directly to 16S ribosomal RNA
FPK90_RS07040	COG0196	riboflavin kinase activity
FPK90_RS07045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FPK90_RS07050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FPK90_RS07055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FPK90_RS07070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPK90_RS07075	COG1845	cytochrome c oxidase, subunit III
FPK90_RS07080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FPK90_RS07100	COG3152	Membrane
FPK90_RS07110	COG2207	Transcriptional regulator
FPK90_RS07115	COG0326	Molecular chaperone. Has ATPase activity
FPK90_RS07130	COG1366	Belongs to the anti-sigma-factor antagonist family
FPK90_RS07135	COG1366	Belongs to the anti-sigma-factor antagonist family
FPK90_RS07140	COG2172	sigma factor antagonist activity
FPK90_RS07165	COG4771	TonB-dependent receptor
FPK90_RS07175	COG5507	3-demethylubiquinone-9 3-methyltransferase
FPK90_RS07180	COG2205	protein histidine kinase activity
FPK90_RS07190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FPK90_RS07195	COG2205	protein histidine kinase activity
FPK90_RS07195	COG3850	Histidine kinase
FPK90_RS07195	COG3437	response regulator, receiver
FPK90_RS07195	COG4999	Histidine kinase
FPK90_RS07200	COG4191	Histidine kinase
FPK90_RS07200	COG0784	Response regulator, receiver
FPK90_RS07225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPK90_RS07235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FPK90_RS07245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPK90_RS07250	COG0228	four-way junction DNA binding
FPK90_RS07255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FPK90_RS07260	COG0336	Belongs to the RNA methyltransferase TrmD family
FPK90_RS07265	COG0335	large ribosomal subunit rRNA binding
FPK90_RS07270	COG0534	Mate efflux family protein
FPK90_RS07290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FPK90_RS07300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FPK90_RS07335	COG2963	transposase activity
FPK90_RS07350	COG3250	beta-galactosidase activity
FPK90_RS07355	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FPK90_RS07375	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS07380	COG1024	Enoyl-CoA hydratase
FPK90_RS07415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK90_RS07420	COG0481	GTPase activity
FPK90_RS07435	COG0571	ribonuclease III activity
FPK90_RS07440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPK90_RS07445	COG1381	Involved in DNA repair and RecF pathway recombination
FPK90_RS07455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPK90_RS07465	COG2954	triphosphatase activity
FPK90_RS07470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPK90_RS07475	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FPK90_RS07480	COG3046	protein related to deoxyribodipyrimidine photolyase
FPK90_RS07485	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK90_RS07490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FPK90_RS07495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FPK90_RS07500	COG1278	Cold shock
FPK90_RS07520	COG1201	RNA secondary structure unwinding
FPK90_RS07525	COG1793	dna ligase
FPK90_RS07535	COG1793	dna ligase
FPK90_RS07535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FPK90_RS07565	COG0183	Belongs to the thiolase family
FPK90_RS07590	COG1451	nucleotide metabolic process
FPK90_RS07595	COG5487	UPF0391 membrane protein
FPK90_RS07605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FPK90_RS07620	COG1077	Cell shape determining protein MreB Mrl
FPK90_RS07625	COG1047	Peptidyl-prolyl cis-trans
FPK90_RS07635	COG2824	Alkylphosphonate utilization operon protein PhnA
FPK90_RS07645	COG1902	pentaerythritol trinitrate reductase activity
FPK90_RS07650	COG2814	Major facilitator Superfamily
FPK90_RS07685	COG0392	lysyltransferase activity
FPK90_RS07685	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FPK90_RS07695	COG0251	oxidation-reduction process
FPK90_RS07700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK90_RS07715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK90_RS07740	COG1595	DNA-templated transcription, initiation
FPK90_RS07760	COG2878	Part of a membrane complex involved in electron transport
FPK90_RS07770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPK90_RS07770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPK90_RS07785	COG1131	(ABC) transporter
FPK90_RS07790	COG0346	lactoylglutathione lyase activity
FPK90_RS07795	COG0833	amino acid
FPK90_RS07800	COG2040	homocysteine
FPK90_RS07810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FPK90_RS07830	COG1695	Transcriptional regulator
FPK90_RS07850	COG1981	membrane
FPK90_RS07865	COG0825	malonyl-CoA metabolic process
FPK90_RS07875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FPK90_RS07880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPK90_RS07885	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPK90_RS07890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPK90_RS07895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FPK90_RS07910	COG0750	zinc metalloprotease
FPK90_RS07915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FPK90_RS07920	COG0575	Belongs to the CDS family
FPK90_RS07925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FPK90_RS07930	COG0233	cytoplasmic translational termination
FPK90_RS07935	COG0528	UMP kinase activity
FPK90_RS07945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPK90_RS07950	COG0052	Belongs to the universal ribosomal protein uS2 family
FPK90_RS07990	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FPK90_RS08000	COG1393	Belongs to the ArsC family
FPK90_RS08005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPK90_RS08010	COG0367	asparagine synthase
FPK90_RS08020	COG4774	siderophore transport
FPK90_RS08035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPK90_RS08070	COG1566	PFAM secretion protein HlyD family protein
FPK90_RS08075	COG2814	Major facilitator Superfamily
FPK90_RS08125	COG0339	signal peptide processing
FPK90_RS08135	COG0386	Belongs to the glutathione peroxidase family
FPK90_RS08190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FPK90_RS08195	COG0084	hydrolase, TatD family'
FPK90_RS08210	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS08230	COG0367	asparagine synthase
FPK90_RS08240	COG0305	Participates in initiation and elongation during chromosome replication
FPK90_RS08245	COG0415	Belongs to the DNA photolyase family
FPK90_RS08265	COG0583	DNA-binding transcription factor activity
FPK90_RS08310	COG3706	GGDEF domain
FPK90_RS08345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FPK90_RS08360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPK90_RS08370	COG0497	DNA recombination
FPK90_RS08375	COG1420	regulation of RNA biosynthetic process
FPK90_RS08380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FPK90_RS08385	COG0443	Heat shock 70 kDa protein
FPK90_RS08390	COG0484	heat shock protein binding
FPK90_RS08430	COG0583	DNA-binding transcription factor activity
FPK90_RS08435	COG1132	(ABC) transporter
FPK90_RS08470	COG2850	peptidyl-arginine hydroxylation
FPK90_RS08490	COG1253	flavin adenine dinucleotide binding
FPK90_RS08520	COG1131	(ABC) transporter
FPK90_RS08525	COG1725	Transcriptional regulator
FPK90_RS08535	COG0386	Belongs to the glutathione peroxidase family
FPK90_RS08550	COG2900	Belongs to the SlyX family
FPK90_RS08575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPK90_RS08585	COG1410	methionine synthase
FPK90_RS08585	COG0646	methionine synthase
FPK90_RS08590	COG1410	methionine synthase
FPK90_RS08590	COG0646	methionine synthase
FPK90_RS08595	COG2226	methyltransferase
FPK90_RS08600	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS08605	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS08625	COG0557	exoribonuclease II activity
FPK90_RS08635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPK90_RS08645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPK90_RS08655	COG0704	Plays a role in the regulation of phosphate uptake
FPK90_RS08660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPK90_RS08665	COG0581	inorganic phosphate transmembrane transporter activity
FPK90_RS08670	COG0573	inorganic phosphate transmembrane transporter activity
FPK90_RS08675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPK90_RS08700	COG0659	secondary active sulfate transmembrane transporter activity
FPK90_RS08705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FPK90_RS08715	COG1024	Enoyl-CoA hydratase
FPK90_RS08725	COG0494	nUDIX hydrolase
FPK90_RS08760	COG0488	(ABC) transporter
FPK90_RS08770	COG0116	Belongs to the methyltransferase superfamily
FPK90_RS08770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FPK90_RS08775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FPK90_RS08800	COG2925	Exonuclease
FPK90_RS08810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPK90_RS08815	COG3844	kynureninase activity
FPK90_RS08825	COG0662	Cupin 2, conserved barrel domain protein
FPK90_RS08830	COG0288	reversible hydration of carbon dioxide
FPK90_RS08895	COG2808	Putative FMN-binding domain
FPK90_RS08915	COG0017	Asparaginyl-tRNA synthetase
FPK90_RS08925	COG0316	Belongs to the HesB IscA family
FPK90_RS08930	COG0360	Binds together with S18 to 16S ribosomal RNA
FPK90_RS08935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FPK90_RS08940	COG0359	binds to the 23S rRNA
FPK90_RS08950	COG3115	cell septum assembly
FPK90_RS08960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPK90_RS08965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FPK90_RS08970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FPK90_RS08985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FPK90_RS08995	COG4993	Dehydrogenase
FPK90_RS09010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FPK90_RS09020	COG2986	histidine ammonia-lyase
FPK90_RS09025	COG1228	amidohydrolase
FPK90_RS09070	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FPK90_RS09075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPK90_RS09080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FPK90_RS09085	COG1605	Chorismate mutase
FPK90_RS09085	COG0077	Prephenate dehydratase
FPK90_RS09090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPK90_RS09105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FPK90_RS09110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPK90_RS09115	COG0583	DNA-binding transcription factor activity
FPK90_RS09130	COG0840	transmembrane signaling receptor activity
FPK90_RS09165	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FPK90_RS09170	COG4191	Histidine kinase
FPK90_RS09170	COG0784	Response regulator, receiver
FPK90_RS09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPK90_RS09195	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FPK90_RS09205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPK90_RS09220	COG1595	DNA-templated transcription, initiation
FPK90_RS09275	COG2244	polysaccharide biosynthetic process
FPK90_RS09305	COG2264	protein methyltransferase activity
FPK90_RS09330	COG1136	(ABC) transporter
FPK90_RS09340	COG0477	Major facilitator Superfamily
FPK90_RS09345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK90_RS09360	COG1253	flavin adenine dinucleotide binding
FPK90_RS09375	COG0306	phosphate transporter
FPK90_RS09400	COG0504	CTP synthase activity
FPK90_RS09405	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FPK90_RS09415	COG0148	phosphopyruvate hydratase activity
FPK90_RS09420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FPK90_RS09425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FPK90_RS09430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FPK90_RS09435	COG0585	pseudouridine synthase activity
FPK90_RS09440	COG2840	Smr protein MutS2
FPK90_RS09445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FPK90_RS09450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FPK90_RS09455	COG1238	metal cluster binding
FPK90_RS09470	COG1534	Rna-binding protein
FPK90_RS09475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FPK90_RS09485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FPK90_RS09490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FPK90_RS09500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPK90_RS09505	COG1546	Belongs to the CinA family
FPK90_RS09515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FPK90_RS09520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FPK90_RS09530	COG2137	regulation of response to DNA damage stimulus
FPK90_RS09535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPK90_RS09540	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FPK90_RS09700	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FPK90_RS09755	COG3179	chitinase
FPK90_RS09835	COG1196	nuclear chromosome segregation
FPK90_RS09900	COG0582	viral genome integration into host DNA
FPK90_RS09915	COG1741	Belongs to the pirin family
FPK90_RS09920	COG0583	DNA-binding transcription factor activity
FPK90_RS09945	COG0351	phosphomethylpyrimidine kinase
FPK90_RS09960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FPK90_RS09965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FPK90_RS09980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPK90_RS09990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPK90_RS09995	COG3734	2-keto-3-deoxy-galactonokinase
FPK90_RS10005	COG4948	Mandelate Racemase Muconate Lactonizing
FPK90_RS10010	COG0800	Aldolase
FPK90_RS10050	COG1501	Belongs to the glycosyl hydrolase 31 family
FPK90_RS10060	COG1070	Carbohydrate kinase
FPK90_RS10065	COG2115	Belongs to the xylose isomerase family
FPK90_RS10070	COG0477	Major facilitator Superfamily
FPK90_RS10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPK90_RS10095	COG1469	GTP cyclohydrolase I activity
FPK90_RS10115	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FPK90_RS10120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FPK90_RS10125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FPK90_RS10130	COG0166	Belongs to the GPI family
FPK90_RS10155	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK90_RS10170	COG3706	GGDEF domain
FPK90_RS10170	COG4251	negative regulation of phosphorylation
FPK90_RS10170	COG5001	Diguanylate cyclase
FPK90_RS10170	COG2203	Gaf domain
FPK90_RS10175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FPK90_RS10180	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FPK90_RS10190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FPK90_RS10195	COG0671	phosphoesterase, PA-phosphatase related
FPK90_RS10210	COG1794	racemase activity, acting on amino acids and derivatives
FPK90_RS10220	COG0697	spore germination
FPK90_RS10225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPK90_RS10230	COG0167	dihydroorotate dehydrogenase activity
FPK90_RS10250	COG1012	belongs to the aldehyde dehydrogenase family
FPK90_RS10310	COG2003	Belongs to the UPF0758 family
FPK90_RS10385	COG0758	DNA mediated transformation
FPK90_RS10485	COG2814	Major facilitator Superfamily
FPK90_RS10550	COG3621	Patatin-like phospholipase
FPK90_RS10600	COG1215	transferase activity, transferring glycosyl groups
FPK90_RS10605	COG1649	PFAM Uncharacterised BCR, COG1649
FPK90_RS10605	COG0726	polysaccharide deacetylase
FPK90_RS10690	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FPK90_RS10725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPK90_RS10730	COG0124	histidyl-tRNA synthetase
FPK90_RS10740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FPK90_RS10745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FPK90_RS10750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPK90_RS10755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FPK90_RS10755	COG0131	Imidazoleglycerol-phosphate dehydratase
FPK90_RS10760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FPK90_RS10765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FPK90_RS10770	COG0107	imidazoleglycerol-phosphate synthase activity
FPK90_RS10775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FPK90_RS10775	COG0140	phosphoribosyl-ATP diphosphatase activity
FPK90_RS10790	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FPK90_RS10795	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FPK90_RS10800	COG0235	Class ii aldolase
FPK90_RS10805	COG0531	amino acid
FPK90_RS10810	COG0531	amino acid
FPK90_RS10820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPK90_RS10825	COG0277	FAD linked oxidase domain protein
FPK90_RS10845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPK90_RS10890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPK90_RS10895	COG2258	MOSC domain
FPK90_RS10900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FPK90_RS10905	COG0505	Belongs to the CarA family
FPK90_RS10915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FPK90_RS10920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FPK90_RS10930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPK90_RS10940	COG3279	Response regulator of the LytR AlgR family
FPK90_RS10950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FPK90_RS10960	COG0784	Response regulator, receiver
FPK90_RS10960	COG2205	protein histidine kinase activity
FPK90_RS10960	COG2198	Histidine kinase
FPK90_RS10965	COG0784	Response regulator, receiver
FPK90_RS10965	COG2205	protein histidine kinase activity
FPK90_RS10965	COG2198	Histidine kinase
FPK90_RS10970	COG1024	Enoyl-CoA hydratase
FPK90_RS10975	COG0318	PFAM AMP-dependent synthetase and ligase
FPK90_RS11005	COG2267	carboxylic ester hydrolase activity
FPK90_RS11015	COG2201	protein-glutamate methylesterase activity
FPK90_RS11020	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FPK90_RS11030	COG0840	transmembrane signaling receptor activity
FPK90_RS11040	COG0835	chemotaxis
FPK90_RS11055	COG0840	transmembrane signaling receptor activity
FPK90_RS11060	COG0840	transmembrane signaling receptor activity
FPK90_RS11065	COG0840	transmembrane signaling receptor activity
FPK90_RS11075	COG0840	transmembrane signaling receptor activity
FPK90_RS11085	COG0840	transmembrane signaling receptor activity
FPK90_RS11090	COG0840	transmembrane signaling receptor activity
FPK90_RS11095	COG0840	transmembrane signaling receptor activity
FPK90_RS11100	COG0840	transmembrane signaling receptor activity
FPK90_RS11115	COG0840	transmembrane signaling receptor activity
FPK90_RS11135	COG0643	Histidine kinase
FPK90_RS11135	COG2198	Histidine kinase
FPK90_RS11140	COG0745	RESPONSE REGULATOR receiver
FPK90_RS11150	COG0835	chemotaxis
FPK90_RS11160	COG1360	Flagellar Motor Protein
FPK90_RS11165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FPK90_RS11265	COG0641	radical SAM
FPK90_RS11280	COG0643	Histidine kinase
FPK90_RS11280	COG0784	Response regulator, receiver
FPK90_RS11280	COG2198	Histidine kinase
FPK90_RS11310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPK90_RS11340	COG1684	flagellar biosynthetic protein fliR
FPK90_RS11355	COG3190	flagellar
FPK90_RS11405	COG1677	Flagellar hook-basal body complex protein FliE
FPK90_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS11450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPK90_RS11470	COG2201	protein-glutamate methylesterase activity
FPK90_RS11500	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FPK90_RS11505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPK90_RS11510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPK90_RS11520	COG1705	Flagellar rod assembly protein muramidase FlgJ
FPK90_RS11520	COG3951	Flagellar rod assembly protein muramidase FlgJ
FPK90_RS11525	COG1706	bacterial-type flagellum-dependent cell motility
FPK90_RS11530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FPK90_RS11545	COG4787	bacterial-type flagellum-dependent cell motility
FPK90_RS11555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FPK90_RS11560	COG1558	bacterial-type flagellum-dependent cell motility
FPK90_RS11570	COG0784	Response regulator, receiver
FPK90_RS11570	COG0835	chemotaxis
FPK90_RS11590	COG5002	protein histidine kinase activity
FPK90_RS11620	COG2915	High frequency lysogenization protein hflD homolog
FPK90_RS11625	COG0482	sulfurtransferase activity
FPK90_RS11640	COG0542	response to heat
FPK90_RS11650	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FPK90_RS11660	COG0492	ferredoxin-NADP+ reductase activity
FPK90_RS11665	COG1674	ftsk spoiiie
FPK90_RS11675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FPK90_RS11685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FPK90_RS11690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FPK90_RS11700	COG0183	Belongs to the thiolase family
FPK90_RS11705	COG1024	Enoyl-CoA hydratase
FPK90_RS11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPK90_RS11720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPK90_RS11730	COG1426	Protein conserved in bacteria
FPK90_RS11740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPK90_RS11745	COG1160	GTP binding
FPK90_RS11750	COG0303	'Molybdopterin
FPK90_RS11755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPK90_RS11795	COG0708	Exodeoxyribonuclease III
FPK90_RS11805	COG0303	'Molybdopterin
FPK90_RS11810	COG0746	molybdenum cofactor guanylyltransferase activity
FPK90_RS11820	COG1648	precorrin-2 dehydrogenase activity
FPK90_RS11820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPK90_RS11850	COG3685	Protein conserved in bacteria
FPK90_RS11870	COG5001	Diguanylate cyclase
FPK90_RS11880	COG4566	intracellular signal transduction
FPK90_RS11920	COG3275	phosphorelay sensor kinase activity
FPK90_RS11925	COG3279	Response regulator of the LytR AlgR family
FPK90_RS11960	COG1238	metal cluster binding
FPK90_RS12070	COG0653	protein targeting
FPK90_RS12085	COG0653	protein targeting
FPK90_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS12100	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FPK90_RS12105	COG1073	alpha beta
FPK90_RS12105	COG2226	methyltransferase
FPK90_RS12155	COG0316	Belongs to the HesB IscA family
FPK90_RS12155	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FPK90_RS12160	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPK90_RS12170	COG0428	transporter
FPK90_RS12175	COG3064	Membrane
FPK90_RS12185	COG1530	ribonuclease E activity
FPK90_RS12195	COG1054	Belongs to the UPF0176 family
FPK90_RS12215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FPK90_RS12290	COG5599	Phosphatase
FPK90_RS12305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPK90_RS12310	COG1061	Type III restriction enzyme res subunit
FPK90_RS12315	COG1002	Type II restriction enzyme, methylase subunits
FPK90_RS12380	COG0629	single-stranded DNA binding
FPK90_RS12385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPK90_RS12395	COG0270	DNA (cytosine-5-)-methyltransferase activity
FPK90_RS12575	COG0583	DNA-binding transcription factor activity
FPK90_RS12580	COG0477	Major facilitator Superfamily
FPK90_RS12595	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS12605	COG2816	NAD+ diphosphatase activity
FPK90_RS12615	COG2814	Major facilitator Superfamily
FPK90_RS12900	COG0583	DNA-binding transcription factor activity
FPK90_RS12915	COG0582	viral genome integration into host DNA
FPK90_RS12925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPK90_RS12930	COG0322	excinuclease ABC activity
FPK90_RS12940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPK90_RS12945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FPK90_RS12950	COG1663	tetraacyldisaccharide 4'-kinase activity
FPK90_RS12955	COG1132	(ABC) transporter
FPK90_RS12965	COG0811	peptide transport
FPK90_RS12980	COG1136	(ABC) transporter
FPK90_RS12985	COG4591	ABC-type transport system involved in lipoprotein release permease component
FPK90_RS12995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FPK90_RS13000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPK90_RS13015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FPK90_RS13040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPK90_RS13045	COG0837	glucose binding
FPK90_RS13050	COG0363	glucosamine-6-phosphate deaminase activity
FPK90_RS13055	COG0129	dihydroxy-acid dehydratase activity
FPK90_RS13060	COG0800	Aldolase
FPK90_RS13135	COG0784	Response regulator, receiver
FPK90_RS13135	COG2205	protein histidine kinase activity
FPK90_RS13140	COG2183	response to ionizing radiation
FPK90_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPK90_RS13150	COG0723	plastoquinol--plastocyanin reductase activity
FPK90_RS13165	COG3243	poly(R)-hydroxyalkanoic acid synthase
FPK90_RS13175	COG1183	phosphatidylcholine synthase activity
FPK90_RS13180	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS13195	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FPK90_RS13205	COG0668	transmembrane transport
FPK90_RS13210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FPK90_RS13225	COG1914	H( )-stimulated, divalent metal cation uptake system
FPK90_RS13245	COG2814	Major facilitator Superfamily
FPK90_RS13260	COG1335	isochorismatase
FPK90_RS13275	COG2197	response regulator
FPK90_RS13295	COG0583	DNA-binding transcription factor activity
FPK90_RS13300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPK90_RS13305	COG3002	Belongs to the UPF0753 family
FPK90_RS13310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPK90_RS13310	COG0519	Catalyzes the synthesis of GMP from XMP
FPK90_RS13320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FPK90_RS13330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPK90_RS13330	COG0475	glutathione-regulated potassium exporter activity
FPK90_RS13340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPK90_RS13350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPK90_RS13355	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FPK90_RS13365	COG0776	regulation of translation
FPK90_RS13370	COG0539	negative regulation of cytoplasmic translation
FPK90_RS13375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FPK90_RS13395	COG2957	Belongs to the agmatine deiminase family
FPK90_RS13400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPK90_RS13425	COG0395	ABC-type sugar transport system, permease component
FPK90_RS13430	COG1175	transmembrane transport
FPK90_RS13460	COG2350	Protein conserved in bacteria
FPK90_RS13465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FPK90_RS13470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPK90_RS13475	COG1187	pseudouridine synthase activity
FPK90_RS13495	COG0436	Aminotransferase
FPK90_RS13500	COG4133	protoheme IX ABC transporter activity
FPK90_RS13520	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FPK90_RS13525	COG1138	Cytochrome C-type biogenesis protein
FPK90_RS13545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPK90_RS13550	COG1278	Cold shock
FPK90_RS13555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FPK90_RS13560	COG4988	ABC transporter
FPK90_RS13570	COG1294	oxidase, subunit
FPK90_RS13600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FPK90_RS13605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FPK90_RS13615	COG0165	Argininosuccinate lyase
FPK90_RS13620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FPK90_RS13630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPK90_RS13635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPK90_RS13645	COG0137	argininosuccinate synthase activity
FPK90_RS13650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FPK90_RS13660	COG0215	cysteine-tRNA ligase activity
FPK90_RS13665	COG2166	iron-sulfur cluster assembly
FPK90_RS13680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPK90_RS13685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FPK90_RS13715	COG4302	ethanolamine ammonia-lyase activity
FPK90_RS13780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPK90_RS13785	COG0402	S-adenosylhomocysteine deaminase activity
FPK90_RS13795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPK90_RS13800	COG1509	lysine 2,3-aminomutase activity
FPK90_RS13805	COG5001	Diguanylate cyclase
FPK90_RS13805	COG3300	MHYT domain
FPK90_RS13820	COG0483	inositol monophosphate 1-phosphatase activity
FPK90_RS13825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPK90_RS13845	COG0488	(ABC) transporter
FPK90_RS13850	COG0513	Belongs to the DEAD box helicase family
FPK90_RS13855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPK90_RS13860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FPK90_RS13870	COG0625	glutathione transferase activity
FPK90_RS13880	COG4681	YaeQ
FPK90_RS13885	COG2081	HI0933 family
FPK90_RS13895	COG0501	Belongs to the peptidase M48B family
FPK90_RS13900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPK90_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS13930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FPK90_RS13935	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPK90_RS13940	COG0802	atpase or kinase
FPK90_RS13945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FPK90_RS13945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FPK90_RS13950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPK90_RS13955	COG1570	exodeoxyribonuclease VII activity
FPK90_RS13965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FPK90_RS14010	COG0835	chemotaxis
FPK90_RS14015	COG0840	transmembrane signaling receptor activity
FPK90_RS14020	COG2094	Belongs to the DNA glycosylase MPG family
FPK90_RS14025	COG1201	RNA secondary structure unwinding
FPK90_RS14045	COG2969	positive regulation of protein catabolic process
FPK90_RS14050	COG0625	glutathione transferase activity
FPK90_RS14055	COG2857	Cytochrome c1
FPK90_RS14060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FPK90_RS14065	COG0723	plastoquinol--plastocyanin reductase activity
FPK90_RS14075	COG0741	lytic transglycosylase activity
FPK90_RS14090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPK90_RS14100	COG1702	phosphate starvation-inducible protein PhoH
FPK90_RS14110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FPK90_RS14120	COG4535	Mg2 and Co2 transporter CorC
FPK90_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
FPK90_RS14140	COG1177	transmembrane transport
FPK90_RS14145	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPK90_RS14170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FPK90_RS14190	COG0174	glutamine synthetase
FPK90_RS14195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPK90_RS14205	COG2703	oxygen carrier activity
FPK90_RS14210	COG0477	Major facilitator Superfamily
FPK90_RS14225	COG0243	molybdopterin cofactor binding
FPK90_RS14230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FPK90_RS14235	COG2223	nitrite transmembrane transporter activity
FPK90_RS14250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPK90_RS14260	COG2733	membrane
FPK90_RS14265	COG5002	protein histidine kinase activity
FPK90_RS14265	COG0784	Response regulator, receiver
FPK90_RS14265	COG2205	protein histidine kinase activity
FPK90_RS14275	COG0477	Major facilitator Superfamily
FPK90_RS14290	COG2902	Dehydrogenase
FPK90_RS14300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS14305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPK90_RS14315	COG1609	Transcriptional regulator
FPK90_RS14320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPK90_RS14320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPK90_RS14325	COG1105	Belongs to the carbohydrate kinase PfkB family
FPK90_RS14330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPK90_RS14330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPK90_RS14350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPK90_RS14360	COG1862	Preprotein translocase
FPK90_RS14365	COG0343	queuine tRNA-ribosyltransferase activity
FPK90_RS14370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FPK90_RS14410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FPK90_RS14415	COG3291	Pkd domain containing protein
FPK90_RS14420	COG0405	Gamma-glutamyltransferase
FPK90_RS14425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FPK90_RS14440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FPK90_RS14445	COG0742	ribosomal rna small subunit methyltransferase
FPK90_RS14450	COG0326	Molecular chaperone. Has ATPase activity
FPK90_RS14580	COG0531	amino acid
FPK90_RS14595	COG0006	proline dipeptidase activity
FPK90_RS14605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPK90_RS14620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPK90_RS14625	COG3938	Belongs to the proline racemase family
FPK90_RS14635	COG0552	protein localization to endoplasmic reticulum
FPK90_RS14645	COG1194	a g-specific adenine glycosylase
FPK90_RS14650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FPK90_RS14655	COG4191	Histidine kinase
FPK90_RS14655	COG0784	Response regulator, receiver
FPK90_RS14670	COG0322	excinuclease ABC activity
FPK90_RS14685	COG3040	lipid binding
FPK90_RS14700	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS14710	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FPK90_RS14730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPK90_RS14735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK90_RS14740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPK90_RS14765	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS14775	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS14780	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS14830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPK90_RS14830	COG0072	phenylalanine-tRNA ligase activity
FPK90_RS14835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FPK90_RS14850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FPK90_RS14855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPK90_RS14870	COG2211	Major facilitator Superfamily
FPK90_RS14880	COG1082	Xylose isomerase domain protein TIM barrel
FPK90_RS14895	COG0366	Alpha amylase catalytic
FPK90_RS14965	COG3702	type iv secretory pathway
FPK90_RS14985	COG2948	multi-organism process
FPK90_RS15005	COG3505	Type IV secretory pathway VirD4
FPK90_RS15020	COG0556	nucleotide-excision repair
FPK90_RS15065	COG1611	Belongs to the LOG family
FPK90_RS15080	COG2095	MarC family integral membrane protein
FPK90_RS15090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FPK90_RS15125	COG1185	polyribonucleotide nucleotidyltransferase activity
FPK90_RS15130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FPK90_RS15135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FPK90_RS15140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FPK90_RS15145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FPK90_RS15150	COG0195	Participates in both transcription termination and antitermination
FPK90_RS15155	COG0779	Required for maturation of 30S ribosomal subunits
FPK90_RS15165	COG1007	ATP synthesis coupled electron transport
FPK90_RS15190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPK90_RS15195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FPK90_RS15205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FPK90_RS15210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FPK90_RS15215	COG0649	NAD binding
FPK90_RS15220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPK90_RS15225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPK90_RS15230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPK90_RS15245	COG0149	triose-phosphate isomerase activity
FPK90_RS15250	COG0300	oxidoreductase activity
FPK90_RS15280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPK90_RS15285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FPK90_RS15290	COG0159	tryptophan synthase activity
FPK90_RS15300	COG0133	tryptophan synthase activity
FPK90_RS15310	COG0135	phosphoribosylanthranilate isomerase activity
FPK90_RS15315	COG0101	tRNA pseudouridine synthase activity
FPK90_RS15335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPK90_RS15340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPK90_RS15345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FPK90_RS15350	COG2890	protein-(glutamine-N5) methyltransferase activity
FPK90_RS15360	COG0688	phosphatidylethanolamine metabolic process
FPK90_RS15375	COG0433	COG0433 Predicted ATPase
FPK90_RS15380	COG0494	nUDIX hydrolase
FPK90_RS15400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FPK90_RS15405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPK90_RS15415	COG2336	PFAM SpoVT AbrB
FPK90_RS15455	COG0420	3'-5' exonuclease activity
FPK90_RS15495	COG0717	Belongs to the dCTP deaminase family
FPK90_RS15505	COG0489	protein tyrosine kinase activity
FPK90_RS15525	COG3590	peptidase
FPK90_RS15535	COG3590	peptidase
FPK90_RS15555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPK90_RS15560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPK90_RS15565	COG2311	Membrane
FPK90_RS15570	COG1047	Peptidyl-prolyl cis-trans
FPK90_RS15575	COG0791	NLP P60 protein
FPK90_RS15580	COG0791	NLP P60 protein
FPK90_RS15590	COG4106	trans-aconitate 2-methyltransferase activity
FPK90_RS15595	COG1301	dicarboxylic acid transport
FPK90_RS15600	COG1785	Belongs to the alkaline phosphatase family
FPK90_RS15610	COG0037	tRNA processing
FPK90_RS15615	COG1722	exodeoxyribonuclease VII activity
FPK90_RS15620	COG0142	geranyltranstransferase activity
FPK90_RS15625	COG4104	PAAR repeat-containing protein
FPK90_RS15635	COG0312	modulator of DNA gyrase
FPK90_RS15640	COG3028	Belongs to the UPF0307 family
FPK90_RS15645	COG0312	modulator of DNA gyrase
FPK90_RS15655	COG3164	Protein of unknown function
FPK90_RS15665	COG0424	maF-like protein
FPK90_RS15670	COG2968	Membrane
FPK90_RS15685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPK90_RS15700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPK90_RS15715	COG0495	leucyl-tRNA aminoacylation
FPK90_RS15725	COG3118	belongs to the thioredoxin family
FPK90_RS15750	COG2155	Conserved Protein
FPK90_RS15795	COG1132	(ABC) transporter
FPK90_RS15825	COG1538	Outer membrane efflux protein
FPK90_RS15830	COG0745	RESPONSE REGULATOR receiver
FPK90_RS15835	COG5002	protein histidine kinase activity
FPK90_RS15835	COG5000	phosphorelay sensor kinase activity
FPK90_RS15840	COG0475	glutathione-regulated potassium exporter activity
FPK90_RS15850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPK90_RS15875	COG1187	pseudouridine synthase activity
FPK90_RS15880	COG5002	protein histidine kinase activity
FPK90_RS15880	COG5001	Diguanylate cyclase
FPK90_RS15990	COG2951	lytic endotransglycosylase activity
FPK90_RS15995	COG4644	lycopene metabolic process
FPK90_RS16010	COG2369	cell adhesion
FPK90_RS16060	COG0667	Aldo Keto reductase
FPK90_RS16065	COG2814	Major facilitator Superfamily
FPK90_RS16070	COG0583	DNA-binding transcription factor activity
FPK90_RS16075	COG2207	Transcriptional regulator
FPK90_RS16090	COG0667	Aldo Keto reductase
FPK90_RS16095	COG1309	transcriptional regulator
FPK90_RS16105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPK90_RS16120	COG0735	belongs to the Fur family
FPK90_RS16125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPK90_RS16150	COG4452	Inner membrane protein CreD
FPK90_RS16165	COG2205	protein histidine kinase activity
FPK90_RS16170	COG0745	RESPONSE REGULATOR receiver
FPK90_RS16175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FPK90_RS16190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FPK90_RS16200	COG2198	Histidine kinase
FPK90_RS16200	COG0643	Histidine kinase
FPK90_RS16205	COG0840	transmembrane signaling receptor activity
FPK90_RS16210	COG0835	chemotaxis
FPK90_RS16215	COG2199	diguanylate cyclase activity
FPK90_RS16215	COG2200	EAL domain
FPK90_RS16215	COG2202	Pas domain
FPK90_RS16220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FPK90_RS16225	COG2201	protein-glutamate methylesterase activity
FPK90_RS16230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPK90_RS16235	COG3590	peptidase
FPK90_RS16245	COG0588	phosphoglycerate mutase activity
FPK90_RS16250	COG1515	deoxyribonuclease V activity
FPK90_RS16260	COG1741	Belongs to the pirin family
FPK90_RS16275	COG1741	Belongs to the pirin family
FPK90_RS16280	COG1966	Carbon starvation protein
FPK90_RS16285	COG2879	small protein
FPK90_RS16330	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FPK90_RS16335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FPK90_RS16340	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FPK90_RS16345	COG2080	2 iron, 2 sulfur cluster binding
FPK90_RS16355	COG4251	negative regulation of phosphorylation
FPK90_RS16355	COG3706	GGDEF domain
FPK90_RS16355	COG5001	Diguanylate cyclase
FPK90_RS16355	COG2203	Gaf domain
FPK90_RS16360	COG0629	single-stranded DNA binding
FPK90_RS16365	COG0142	geranyltranstransferase activity
FPK90_RS16375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FPK90_RS16390	COG0527	aspartate kinase activity
FPK90_RS16395	COG0384	phenazine biosynthesis protein PhzF
FPK90_RS16400	COG0384	phenazine biosynthesis protein PhzF
FPK90_RS16410	COG1764	response to oxidative stress
FPK90_RS16415	COG0540	Belongs to the ATCase OTCase family
FPK90_RS16420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FPK90_RS16425	COG1678	Uncharacterized ACR, COG1678
FPK90_RS16435	COG0519	Catalyzes the synthesis of GMP from XMP
FPK90_RS16460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPK90_RS16475	COG0739	heme binding
FPK90_RS16495	COG0693	protein deglycase activity
FPK90_RS16505	COG1959	2 iron, 2 sulfur cluster binding
FPK90_RS16510	COG0719	Fe-S assembly protein
FPK90_RS16515	COG0396	ATPase activity
FPK90_RS16520	COG0719	Fe-S assembly protein
FPK90_RS16525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPK90_RS16535	COG2146	nitrite reductase [NAD(P)H] activity
FPK90_RS16540	COG4774	siderophore transport
FPK90_RS16545	COG3128	pkhd-type hydroxylase
FPK90_RS16570	COG1477	protein flavinylation
FPK90_RS16575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FPK90_RS16590	COG1555	photosystem II stabilization
FPK90_RS16605	COG3178	'Phosphotransferase
FPK90_RS16610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPK90_RS16620	COG0628	permease
FPK90_RS16630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPK90_RS16640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPK90_RS16660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPK90_RS16665	COG0271	Belongs to the BolA IbaG family
FPK90_RS16675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FPK90_RS16685	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FPK90_RS16690	COG1137	ATPase activity
FPK90_RS16705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPK90_RS16710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FPK90_RS16715	COG1660	Displays ATPase and GTPase activities
FPK90_RS16725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPK90_RS16730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPK90_RS16740	COG2239	Acts as a magnesium transporter
FPK90_RS16755	COG1294	oxidase, subunit
FPK90_RS16760	COG1271	oxidase subunit
FPK90_RS16770	COG1113	amino acid transport
FPK90_RS16800	COG2197	response regulator
FPK90_RS16805	COG0531	amino acid
FPK90_RS16835	COG1234	tRNA 3'-trailer cleavage
FPK90_RS16910	COG0754	glutathionylspermidine amidase activity
FPK90_RS16935	COG1842	Phage shock protein A
FPK90_RS16945	COG0259	pyridoxamine-phosphate oxidase activity
FPK90_RS16950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FPK90_RS16955	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FPK90_RS16965	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FPK90_RS16970	COG0477	Major facilitator Superfamily
FPK90_RS16990	COG2205	protein histidine kinase activity
FPK90_RS16990	COG2198	Histidine kinase
FPK90_RS16990	COG0784	Response regulator, receiver
FPK90_RS16995	COG2353	YceI-like domain
FPK90_RS17015	COG1760	l-serine dehydratase
FPK90_RS17030	COG0527	aspartate kinase activity
FPK90_RS17030	COG0460	homoserine dehydrogenase
FPK90_RS17035	COG0626	cystathionine gamma-synthase activity
FPK90_RS17040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPK90_RS17045	COG0739	heme binding
FPK90_RS17050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FPK90_RS17055	COG1272	protein, Hemolysin III
FPK90_RS17060	COG2982	Protein involved in outer membrane biogenesis
FPK90_RS17065	COG0516	GMP reductase activity
FPK90_RS17065	COG0517	IMP dehydrogenase activity
FPK90_RS17070	COG0463	Glycosyl transferase, family 2
FPK90_RS17075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPK90_RS17080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FPK90_RS17090	COG4771	TonB-dependent receptor
FPK90_RS17095	COG1309	transcriptional regulator
FPK90_RS17105	COG1960	acyl-CoA dehydrogenase activity
FPK90_RS17135	COG0509	glycine decarboxylation via glycine cleavage system
FPK90_RS17140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FPK90_RS17165	COG1742	UPF0060 membrane protein
FPK90_RS17170	COG3956	TIGRFAM MazG family protein
FPK90_RS17180	COG0494	nUDIX hydrolase
FPK90_RS17190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPK90_RS17195	COG0837	glucose binding
FPK90_RS17210	COG3858	chitin binding
FPK90_RS17210	COG1388	LysM domain
FPK90_RS17225	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK90_RS17240	COG0531	amino acid
FPK90_RS17250	COG1486	melibiose metabolic process
FPK90_RS17260	COG3537	Alpha-1,2-mannosidase
FPK90_RS17300	COG3142	Participates in the control of copper homeostasis
FPK90_RS17305	COG1446	asparaginase
FPK90_RS17335	COG0784	Response regulator, receiver
FPK90_RS17335	COG0643	Histidine kinase
FPK90_RS17335	COG2198	Histidine kinase
FPK90_RS17340	COG0840	transmembrane signaling receptor activity
FPK90_RS17345	COG0835	chemotaxis
FPK90_RS17360	COG0189	ligase activity
FPK90_RS17370	COG1397	ADP-ribosylglycohydrolase
FPK90_RS17380	COG1199	ATP-dependent helicase activity
FPK90_RS17390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPK90_RS17395	COG1215	transferase activity, transferring glycosyl groups
FPK90_RS17410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FPK90_RS17420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FPK90_RS17425	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FPK90_RS17430	COG0535	radical SAM domain protein
FPK90_RS17435	COG0535	radical SAM domain protein
FPK90_RS17450	COG0837	glucose binding
FPK90_RS17465	COG1643	Atp-dependent helicase
FPK90_RS17470	COG0783	Belongs to the Dps family
FPK90_RS17475	COG0514	ATP-dependent DNA helicase (RecQ)
FPK90_RS17510	COG0840	transmembrane signaling receptor activity
FPK90_RS17530	COG3920	Histidine kinase
FPK90_RS17535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FPK90_RS17775	COG4695	Portal protein
FPK90_RS17815	COG0602	queuosine metabolic process
FPK90_RS17825	COG2885	chlorophyll binding
FPK90_RS17830	COG0823	Involved in the tonB-independent uptake of proteins
FPK90_RS17840	COG0848	biopolymer transport protein
FPK90_RS17850	COG0824	Thioesterase
FPK90_RS17855	COG2255	four-way junction helicase activity
FPK90_RS17865	COG3158	transport of potassium into the cell
FPK90_RS17870	COG0632	four-way junction helicase activity
FPK90_RS17875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FPK90_RS17880	COG0217	transcriptional regulatory protein
FPK90_RS17895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FPK90_RS18020	COG2951	lytic endotransglycosylase activity
FPK90_RS18035	COG0477	Major facilitator Superfamily
FPK90_RS18075	COG0488	(ABC) transporter
FPK90_RS18115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPK90_RS18115	COG4651	solute:proton antiporter activity
FPK90_RS18140	COG4772	TonB-dependent receptor
FPK90_RS18150	COG4264	IucA IucC family
FPK90_RS18165	COG0019	diaminopimelate decarboxylase activity
FPK90_RS18185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FPK90_RS18195	COG1492	cobalamin metabolic process
FPK90_RS18205	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FPK90_RS18230	COG4206	TonB-dependent receptor
FPK90_RS18235	COG0542	response to heat
FPK90_RS18240	COG1116	anion transmembrane transporter activity
FPK90_RS18245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPK90_RS18250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPK90_RS18255	COG0667	Aldo Keto reductase
FPK90_RS18260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK90_RS18265	COG4771	TonB-dependent receptor
FPK90_RS18275	COG2827	Endonuclease containing a URI domain
FPK90_RS18320	COG1877	trehalose-phosphatase activity
FPK90_RS18345	COG0840	transmembrane signaling receptor activity
FPK90_RS18350	COG3011	Protein conserved in bacteria
FPK90_RS18365	COG0564	pseudouridine synthase activity
FPK90_RS18370	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPK90_RS18380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPK90_RS18380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FPK90_RS18390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FPK90_RS18395	COG0045	succinate-CoA ligase (ADP-forming) activity
FPK90_RS18440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FPK90_RS18445	COG0237	dephospho-CoA kinase activity
FPK90_RS18465	COG5002	protein histidine kinase activity
FPK90_RS18470	COG0745	RESPONSE REGULATOR receiver
FPK90_RS18480	COG0189	ligase activity
FPK90_RS18590	COG3657	addiction module killer protein
FPK90_RS18620	COG3209	COG3209 Rhs family protein
FPK90_RS18670	COG2022	thiamine diphosphate biosynthetic process
FPK90_RS18680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FPK90_RS18685	COG3273	potassium ion transport
FPK90_RS18685	COG0471	metal ion transport
FPK90_RS18750	COG2205	protein histidine kinase activity
FPK90_RS18750	COG0784	Response regulator, receiver
FPK90_RS18755	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FPK90_RS18770	COG5297	Belongs to the glycosyl hydrolase family 6
FPK90_RS18780	COG3250	beta-galactosidase activity
FPK90_RS18785	COG4948	Mandelate Racemase Muconate Lactonizing
FPK90_RS18800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPK90_RS18810	COG0308	aminopeptidase N
FPK90_RS18815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPK90_RS18825	COG2895	sulfate adenylyltransferase (ATP) activity
FPK90_RS18825	COG0529	Catalyzes the synthesis of activated sulfate
FPK90_RS18830	COG0175	sulfate reduction
FPK90_RS18835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FPK90_RS18840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPK90_RS18845	COG0175	sulfate reduction
FPK90_RS18865	COG0784	Response regulator, receiver
FPK90_RS18865	COG2198	Histidine kinase
FPK90_RS18865	COG2205	protein histidine kinase activity
FPK90_RS18885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPK90_RS18885	COG1648	precorrin-2 dehydrogenase activity
FPK90_RS18900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FPK90_RS18905	COG3588	fructose-bisphosphate aldolase
FPK90_RS18920	COG0469	pyruvate kinase activity
FPK90_RS18930	COG0126	phosphoglycerate kinase activity
FPK90_RS18955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPK90_RS18965	COG3047	cAMP biosynthetic process
FPK90_RS18970	COG3047	cAMP biosynthetic process
FPK90_RS18980	COG3453	Protein conserved in bacteria
FPK90_RS18980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK90_RS18985	COG0725	ABC transporter, periplasmic molybdate-binding protein
FPK90_RS18990	COG4149	molybdate abc transporter
FPK90_RS18995	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FPK90_RS19030	COG1376	ErfK ybiS ycfS ynhG family protein
FPK90_RS19035	COG0739	heme binding
FPK90_RS19045	COG4773	Receptor
FPK90_RS19050	COG0596	Alpha beta hydrolase
FPK90_RS19055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FPK90_RS19060	COG1301	dicarboxylic acid transport
FPK90_RS19070	COG2304	oxidoreductase activity
FPK90_RS19090	COG0714	Associated with various cellular activities
FPK90_RS19120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FPK90_RS19145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPK90_RS19155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FPK90_RS19165	COG0194	GDP metabolic process
FPK90_RS19170	COG1561	YicC-like family, N-terminal region
FPK90_RS19175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FPK90_RS19185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FPK90_RS19190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPK90_RS19205	COG0006	proline dipeptidase activity
FPK90_RS19215	COG0006	proline dipeptidase activity
FPK90_RS19220	COG3079	Belongs to the UPF0149 family
FPK90_RS19240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPK90_RS19250	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FPK90_RS19260	COG2912	Transglutaminase-like superfamily
FPK90_RS19265	COG1773	rubredoxin
FPK90_RS19270	COG0352	thiamine-phosphate diphosphorylase activity
FPK90_RS19280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPK90_RS19300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPK90_RS19330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPK90_RS19335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPK90_RS19345	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS19355	COG0671	phosphoesterase, PA-phosphatase related
FPK90_RS19360	COG3781	membrane
FPK90_RS19370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPK90_RS19375	COG0563	adenylate kinase activity
FPK90_RS19390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FPK90_RS19400	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FPK90_RS19425	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FPK90_RS19440	COG0840	transmembrane signaling receptor activity
FPK90_RS19445	COG0405	Gamma-glutamyltransferase
FPK90_RS19450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FPK90_RS19470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPK90_RS19480	COG0473	3-isopropylmalate dehydrogenase activity
FPK90_RS19485	COG0066	3-isopropylmalate dehydratase activity
FPK90_RS19490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPK90_RS19510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FPK90_RS19515	COG1538	Outer membrane efflux protein
FPK90_RS19520	COG1519	Transferase
FPK90_RS19530	COG1560	Kdo2-lipid A biosynthetic process
FPK90_RS19560	COG0280	phosphate acetyltransferase
FPK90_RS19560	COG0281	malic enzyme
FPK90_RS19565	COG1301	dicarboxylic acid transport
FPK90_RS19590	COG0583	DNA-binding transcription factor activity
FPK90_RS19600	COG0667	Aldo Keto reductase
FPK90_RS19615	COG2197	response regulator
FPK90_RS19625	COG0642	Histidine kinase
FPK90_RS19645	COG2851	Citrate transporter
FPK90_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS19660	COG2211	Major facilitator Superfamily
FPK90_RS19685	COG1162	GTPase activity
FPK90_RS19720	COG4773	Receptor
FPK90_RS19725	COG0726	polysaccharide deacetylase
FPK90_RS19730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FPK90_RS19745	COG3964	amidohydrolase
FPK90_RS19750	COG0402	S-adenosylhomocysteine deaminase activity
FPK90_RS19775	COG1307	EDD domain protein, DegV family
FPK90_RS19780	COG0242	peptide deformylase activity
FPK90_RS19815	COG0457	Tetratricopeptide repeat
FPK90_RS19820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FPK90_RS19825	COG1215	transferase activity, transferring glycosyl groups
FPK90_RS19830	COG1215	transferase activity, transferring glycosyl groups
FPK90_RS19845	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPK90_RS19900	COG2188	Transcriptional regulator
FPK90_RS19920	COG1450	Type ii and iii secretion system protein
FPK90_RS19935	COG3166	PFAM Fimbrial assembly family protein
FPK90_RS19940	COG3156	type II secretion system protein K
FPK90_RS19945	COG4795	General secretion pathway protein
FPK90_RS19950	COG2165	general secretion pathway protein
FPK90_RS19955	COG4970	Tfp pilus assembly protein FimT
FPK90_RS19960	COG2165	general secretion pathway protein
FPK90_RS19965	COG1459	type II secretion system
FPK90_RS19970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FPK90_RS19975	COG1404	Belongs to the peptidase S8 family
FPK90_RS19980	COG5295	Hep Hag repeat protein
FPK90_RS19985	COG1404	Belongs to the peptidase S8 family
FPK90_RS19990	COG5295	Hep Hag repeat protein
FPK90_RS20000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPK90_RS20000	COG0047	phosphoribosylformylglycinamidine synthase activity
FPK90_RS20015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FPK90_RS20030	COG4974	Belongs to the 'phage' integrase family
FPK90_RS20045	COG0795	lipopolysaccharide-transporting ATPase activity
FPK90_RS20055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPK90_RS20070	COG0525	valine-tRNA ligase activity
FPK90_RS20100	COG1183	phosphatidylcholine synthase activity
FPK90_RS20110	COG0442	prolyl-tRNA aminoacylation
FPK90_RS20125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK90_RS20130	COG1127	ABC transporter
FPK90_RS20135	COG3218	ABC-type transport auxiliary lipoprotein component
FPK90_RS20135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK90_RS20165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPK90_RS20170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FPK90_RS20170	COG0662	Cupin 2, conserved barrel domain protein
FPK90_RS20200	COG2086	electron transfer activity
FPK90_RS20215	COG0463	Glycosyl transferase, family 2
FPK90_RS20235	COG2813	Specifically methylates the guanine in position
FPK90_RS20250	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FPK90_RS20255	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS20275	COG0438	transferase activity, transferring glycosyl groups
FPK90_RS20285	COG0626	cystathionine gamma-synthase activity
FPK90_RS20315	COG0625	glutathione transferase activity
FPK90_RS20330	COG0513	Belongs to the DEAD box helicase family
FPK90_RS20340	COG4206	TonB-dependent receptor
FPK90_RS20350	COG0720	synthase
FPK90_RS20360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FPK90_RS20370	COG1956	GAF domain-containing protein
FPK90_RS20380	COG2819	hydrolase of the alpha beta superfamily
FPK90_RS20390	COG0546	phosphoglycolate phosphatase activity
FPK90_RS20395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPK90_RS20400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPK90_RS20415	COG0339	signal peptide processing
FPK90_RS20470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPK90_RS20475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS20480	COG4591	ABC-type transport system involved in lipoprotein release permease component
FPK90_RS20480	COG1136	(ABC) transporter
FPK90_RS20485	COG0577	efflux transmembrane transporter activity
FPK90_RS20505	COG4191	Histidine kinase
FPK90_RS20510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPK90_RS20525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FPK90_RS20530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FPK90_RS20535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FPK90_RS20540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FPK90_RS20545	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FPK90_RS20550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPK90_RS20560	COG0356	it plays a direct role in the translocation of protons across the membrane
FPK90_RS20580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPK90_RS20590	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPK90_RS20630	COG2011	ABC-type metal ion transport system permease component
FPK90_RS20635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FPK90_RS20640	COG0697	spore germination
FPK90_RS20645	COG1666	GTP binding
FPK90_RS20655	COG5002	protein histidine kinase activity
FPK90_RS20655	COG0784	Response regulator, receiver
FPK90_RS20655	COG2198	Histidine kinase
FPK90_RS20680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPK90_RS20690	COG2813	Specifically methylates the guanine in position
FPK90_RS20710	COG2205	protein histidine kinase activity
FPK90_RS20710	COG2202	Pas domain
FPK90_RS20730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPK90_RS20735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPK90_RS20790	COG0842	Transport permease protein
FPK90_RS20795	COG1131	(ABC) transporter
FPK90_RS20800	COG0025	NhaP-type Na H and K H
FPK90_RS20810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FPK90_RS20815	COG1573	uracil-dna glycosylase
FPK90_RS20825	COG3384	dioxygenase
FPK90_RS20835	COG0583	DNA-binding transcription factor activity
FPK90_RS20845	COG0667	Aldo Keto reductase
FPK90_RS20860	COG3590	peptidase
FPK90_RS20880	COG0531	amino acid
FPK90_RS20895	COG2972	Histidine kinase
FPK90_RS20920	COG3685	Protein conserved in bacteria
FPK90_RS20925	COG3546	catalase activity
FPK90_RS20975	COG1271	oxidase subunit
FPK90_RS20980	COG1294	oxidase, subunit
FPK90_RS20995	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS21000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPK90_RS21020	COG1132	(ABC) transporter
FPK90_RS21035	COG1063	alcohol dehydrogenase
FPK90_RS21110	COG0251	oxidation-reduction process
FPK90_RS21125	COG0840	transmembrane signaling receptor activity
FPK90_RS21140	COG0583	DNA-binding transcription factor activity
FPK90_RS21145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPK90_RS21190	COG0024	Methionine aminopeptidase
FPK90_RS21285	COG0582	viral genome integration into host DNA
FPK90_RS21300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPK90_RS21305	COG1490	D-aminoacyl-tRNA deacylase activity
FPK90_RS21310	COG1560	Kdo2-lipid A biosynthetic process
FPK90_RS21365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPK90_RS21365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPK90_RS21370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FPK90_RS21375	COG0242	peptide deformylase activity
FPK90_RS21380	COG1652	LysM domain
FPK90_RS21385	COG0758	DNA mediated transformation
FPK90_RS21405	COG1754	DNA topoisomerase type I activity
FPK90_RS21405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPK90_RS21410	COG0009	L-threonylcarbamoyladenylate synthase
FPK90_RS21425	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS21440	COG0616	signal peptide processing
FPK90_RS21445	COG0534	Mate efflux family protein
FPK90_RS21465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FPK90_RS21470	COG0625	glutathione transferase activity
FPK90_RS21485	COG1252	NADH dehydrogenase
FPK90_RS21490	COG2860	membrane
FPK90_RS21495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPK90_RS21500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FPK90_RS21505	COG3437	response regulator, receiver
FPK90_RS21510	COG2177	Part of the ABC transporter FtsEX involved in
FPK90_RS21515	COG2884	Cell division ATP-binding protein ftsE
FPK90_RS21525	COG3118	belongs to the thioredoxin family
FPK90_RS21530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FPK90_RS21535	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FPK90_RS21540	COG0583	DNA-binding transcription factor activity
FPK90_RS21560	COG1652	LysM domain
FPK90_RS21565	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FPK90_RS21565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FPK90_RS21570	COG1473	amidohydrolase
FPK90_RS21575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS21580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPK90_RS21590	COG5383	Protein conserved in bacteria
FPK90_RS21635	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FPK90_RS21640	COG3023	N-Acetylmuramoyl-L-alanine amidase
FPK90_RS21650	COG4948	Mandelate Racemase Muconate Lactonizing
FPK90_RS21660	COG0531	amino acid
FPK90_RS21675	COG4682	membrane
FPK90_RS21690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FPK90_RS21695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FPK90_RS21705	COG1610	YqeY-like protein
FPK90_RS21715	COG1295	ribonuclease BN
FPK90_RS21720	COG0358	DNA primase activity
FPK90_RS21735	COG0109	protoheme IX farnesyltransferase activity
FPK90_RS21765	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FPK90_RS21780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPK90_RS21825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FPK90_RS21830	COG0739	heme binding
FPK90_RS21835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FPK90_RS21845	COG2211	Major facilitator Superfamily
FPK90_RS21850	COG0708	Exodeoxyribonuclease III
FPK90_RS21855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPK90_RS21865	COG1192	Involved in chromosome partitioning
FPK90_RS21870	COG1475	DNA binding
FPK90_RS21890	COG0463	Glycosyl transferase, family 2
FPK90_RS21910	COG0756	dUTP diphosphatase activity
FPK90_RS21915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPK90_RS21920	COG2003	Belongs to the UPF0758 family
FPK90_RS21925	COG0018	arginyl-trna synthetase
FPK90_RS21940	COG4221	oxidoreductase activity
FPK90_RS21955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK90_RS21960	COG1166	arginine decarboxylase activity
FPK90_RS21965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FPK90_RS21990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FPK90_RS21990	COG3291	Pkd domain containing protein
FPK90_RS22000	COG0347	Belongs to the P(II) protein family
FPK90_RS22010	COG0606	chelatase, subunit chli
FPK90_RS22025	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FPK90_RS22060	COG1690	Belongs to the RtcB family
FPK90_RS22095	COG1090	epimerase
FPK90_RS22105	COG0642	Histidine kinase
FPK90_RS22135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK90_RS22160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPK90_RS22165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPK90_RS22180	COG0753	catalase activity
FPK90_RS22195	COG2197	response regulator
FPK90_RS22200	COG4585	Histidine kinase
FPK90_RS22205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS22210	COG1136	(ABC) transporter
FPK90_RS22235	COG0697	spore germination
FPK90_RS22255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK90_RS22260	COG0180	Tryptophanyl-tRNA synthetase
FPK90_RS22265	COG3237	CsbD-like
FPK90_RS22310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FPK90_RS22345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FPK90_RS22350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FPK90_RS22350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FPK90_RS22395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPK90_RS22425	COG1199	ATP-dependent helicase activity
FPK90_RS22440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPK90_RS22505	COG0625	glutathione transferase activity
FPK90_RS22545	COG4555	ABC transporter
FPK90_RS22555	COG1476	TRANSCRIPTIONal
FPK90_RS22600	COG0543	2 iron, 2 sulfur cluster binding
FPK90_RS22600	COG0633	Ferredoxin
FPK90_RS22605	COG1131	(ABC) transporter
FPK90_RS22610	COG0842	Transport permease protein
FPK90_RS22620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPK90_RS22655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPK90_RS22665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPK90_RS22680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPK90_RS22680	COG1042	CoA-binding domain protein
FPK90_RS22680	COG0045	succinate-CoA ligase (ADP-forming) activity
FPK90_RS22685	COG2239	Acts as a magnesium transporter
FPK90_RS22705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPK90_RS22710	COG3387	PFAM Glycoside hydrolase 15-related
FPK90_RS22725	COG3100	YcgL domain-containing protein
FPK90_RS22730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPK90_RS22740	COG0463	Glycosyl transferase, family 2
FPK90_RS22750	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS22785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPK90_RS22800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPK90_RS22830	COG0823	Involved in the tonB-independent uptake of proteins
FPK90_RS22830	COG1506	peptidase
FPK90_RS22830	COG4946	Tricorn protease homolog
FPK90_RS22850	COG0408	coproporphyrinogen oxidase activity
FPK90_RS22890	COG0515	serine threonine protein kinase
FPK90_RS22890	COG2815	serine threonine protein kinase
FPK90_RS22895	COG0631	protein serine/threonine phosphatase activity
FPK90_RS23110	COG0210	DNA helicase
FPK90_RS23125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPK90_RS23130	COG0583	DNA-binding transcription factor activity
FPK90_RS23135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPK90_RS23150	COG2159	amidohydrolase
FPK90_RS23175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPK90_RS23195	COG0357	Ribosomal RNA small subunit methyltransferase G
FPK90_RS23200	COG3540	Alkaline phosphatase
FPK90_RS23210	COG2091	lysine biosynthetic process via aminoadipic acid
FPK90_RS23225	COG0708	Exodeoxyribonuclease III
FPK90_RS23230	COG1940	carbohydrate kinase activity
FPK90_RS23230	COG1846	Transcriptional regulator
FPK90_RS23240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPK90_RS23250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPK90_RS23255	COG3162	membrane
FPK90_RS23265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPK90_RS23295	COG3507	Belongs to the glycosyl hydrolase 43 family
FPK90_RS23315	COG1028	Short-chain dehydrogenase reductase Sdr
FPK90_RS23320	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPK90_RS23330	COG4948	Mandelate Racemase Muconate Lactonizing
FPK90_RS23335	COG3254	rhamnose metabolic process
FPK90_RS23340	COG0738	Major facilitator superfamily
FPK90_RS23345	COG1414	Transcriptional regulator
FPK90_RS23350	COG1971	Probably functions as a manganese efflux pump
FPK90_RS23355	COG2205	protein histidine kinase activity
FPK90_RS23370	COG3459	Glycosyltransferase 36 associated
FPK90_RS23375	COG2211	Major facilitator Superfamily
FPK90_RS23380	COG3265	gluconokinase activity
FPK90_RS23390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPK90_RS23410	COG2911	Protein conserved in bacteria
FPK90_RS23415	COG0729	surface antigen
FPK90_RS23450	COG0752	glycyl-tRNA synthetase alpha subunit
FPK90_RS23455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FPK90_RS23475	COG0519	Catalyzes the synthesis of GMP from XMP
FPK90_RS23475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPK90_RS23485	COG0805	protein transport
FPK90_RS23490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPK90_RS23495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPK90_RS23505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FPK90_RS23530	COG2974	May be involved in recombination
FPK90_RS23535	COG0037	tRNA processing
FPK90_RS23545	COG2115	Belongs to the xylose isomerase family
FPK90_RS23555	COG3661	Belongs to the glycosyl hydrolase 67 family
FPK90_RS23565	COG4948	Mandelate Racemase Muconate Lactonizing
FPK90_RS23575	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK90_RS23580	COG0246	Mannitol dehydrogenase
FPK90_RS23630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPK90_RS23660	COG3386	PFAM SMP-30 Gluconolaconase
FPK90_RS23675	COG3250	beta-galactosidase activity
FPK90_RS23680	COG1904	glucuronate isomerase
FPK90_RS23685	COG3693	PFAM glycoside hydrolase, family 10
FPK90_RS23695	COG3693	PFAM glycoside hydrolase, family 10
FPK90_RS23710	COG2211	Major facilitator Superfamily
FPK90_RS23750	COG2937	Belongs to the GPAT DAPAT family
FPK90_RS23785	COG0284	orotidine-5'-phosphate decarboxylase activity
FPK90_RS23790	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FPK90_RS23800	COG3132	Protein of unknown function, DUF480
FPK90_RS23815	COG0210	DNA helicase
FPK90_RS23820	COG1435	thymidine kinase activity
FPK90_RS23830	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FPK90_RS23840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPK90_RS23870	COG3135	benzoate transporter
FPK90_RS23890	COG0676	glucose-6-phosphate 1-epimerase activity
FPK90_RS23900	COG3012	SEC-C Motif Domain Protein
FPK90_RS23905	COG0730	response to heat
FPK90_RS23930	COG0302	gtp cyclohydrolase
FPK90_RS23945	COG1566	PFAM secretion protein HlyD family protein
FPK90_RS23955	COG1289	transmembrane transporter activity
FPK90_RS23960	COG0477	Major facilitator Superfamily
FPK90_RS23970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPK90_RS23990	COG4691	Plasmid stability protein
FPK90_RS23995	COG1487	ribonuclease activity
FPK90_RS24030	COG0564	pseudouridine synthase activity
FPK90_RS24045	COG0439	Biotin carboxylase
FPK90_RS24085	COG1074	ATP-dependent DNA helicase activity
FPK90_RS24090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FPK90_RS24105	COG1127	ABC transporter
FPK90_RS24110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK90_RS24115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK90_RS24130	COG2853	Lipoprotein
FPK90_RS24140	COG0386	Belongs to the glutathione peroxidase family
FPK90_RS24150	COG1322	Protein conserved in bacteria
FPK90_RS24155	COG0604	alcohol dehydrogenase
FPK90_RS24160	COG0583	DNA-binding transcription factor activity
FPK90_RS24175	COG0625	glutathione transferase activity
FPK90_RS24185	COG0531	amino acid
FPK90_RS24190	COG3537	Alpha-1,2-mannosidase
FPK90_RS24205	COG3706	GGDEF domain
FPK90_RS24210	COG3835	regulator
FPK90_RS24215	COG1929	Belongs to the glycerate kinase type-1 family
FPK90_RS24220	COG2271	Major facilitator Superfamily
FPK90_RS24235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FPK90_RS24245	COG0861	Integral membrane protein TerC family
FPK90_RS24260	COG0584	glycerophosphoryl diester phosphodiesterase
FPK90_RS24275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FPK90_RS24280	COG0726	polysaccharide deacetylase
FPK90_RS24285	COG0706	membrane insertase activity
FPK90_RS24290	COG0594	ribonuclease P activity
FPK90_RS24325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPK90_RS24335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK90_RS24490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPK90_RS24500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK90_RS24655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPK90_RS24665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain