locus-tag	class	description
XcfCFBP4885P_RS00025	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS00035	COG0463	Glycosyl transferase, family 2
XcfCFBP4885P_RS00045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP4885P_RS00050	COG3100	YcgL domain-containing protein
XcfCFBP4885P_RS00065	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP4885P_RS00070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP4885P_RS00090	COG2239	Acts as a magnesium transporter
XcfCFBP4885P_RS00105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP4885P_RS00115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP4885P_RS00145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP4885P_RS00150	COG0842	Transport permease protein
XcfCFBP4885P_RS00155	COG1131	(ABC) transporter
XcfCFBP4885P_RS00160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP4885P_RS00175	COG4774	siderophore transport
XcfCFBP4885P_RS00185	COG1230	cation diffusion facilitator family transporter
XcfCFBP4885P_RS00205	COG1476	TRANSCRIPTIONal
XcfCFBP4885P_RS00215	COG4555	ABC transporter
XcfCFBP4885P_RS00250	COG0625	glutathione transferase activity
XcfCFBP4885P_RS00320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP4885P_RS00335	COG1199	ATP-dependent helicase activity
XcfCFBP4885P_RS00365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP4885P_RS00415	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP4885P_RS00435	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP4885P_RS00475	COG3237	CsbD-like
XcfCFBP4885P_RS00480	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP4885P_RS00485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP4885P_RS00505	COG0697	spore germination
XcfCFBP4885P_RS00530	COG1136	(ABC) transporter
XcfCFBP4885P_RS00535	COG3328	transposase activity
XcfCFBP4885P_RS00540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS00545	COG4585	Histidine kinase
XcfCFBP4885P_RS00550	COG2197	response regulator
XcfCFBP4885P_RS00560	COG3328	transposase activity
XcfCFBP4885P_RS00575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP4885P_RS00580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP4885P_RS00605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP4885P_RS00630	COG0642	Histidine kinase
XcfCFBP4885P_RS00640	COG1090	epimerase
XcfCFBP4885P_RS00675	COG1690	Belongs to the RtcB family
XcfCFBP4885P_RS00710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP4885P_RS00725	COG0606	chelatase, subunit chli
XcfCFBP4885P_RS00745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP4885P_RS00745	COG3291	Pkd domain containing protein
XcfCFBP4885P_RS00770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP4885P_RS00775	COG1166	arginine decarboxylase activity
XcfCFBP4885P_RS00800	COG2755	lipolytic protein G-D-S-L family
XcfCFBP4885P_RS00800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP4885P_RS00805	COG4221	oxidoreductase activity
XcfCFBP4885P_RS00820	COG0018	arginyl-trna synthetase
XcfCFBP4885P_RS00825	COG2003	Belongs to the UPF0758 family
XcfCFBP4885P_RS00830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP4885P_RS00835	COG0756	dUTP diphosphatase activity
XcfCFBP4885P_RS00855	COG0463	Glycosyl transferase, family 2
XcfCFBP4885P_RS00875	COG1475	DNA binding
XcfCFBP4885P_RS00880	COG1192	Involved in chromosome partitioning
XcfCFBP4885P_RS00890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP4885P_RS00895	COG0708	Exodeoxyribonuclease III
XcfCFBP4885P_RS00900	COG2211	Major facilitator Superfamily
XcfCFBP4885P_RS00910	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP4885P_RS00915	COG0739	heme binding
XcfCFBP4885P_RS00920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP4885P_RS00965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP4885P_RS00980	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP4885P_RS01010	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP4885P_RS01025	COG0358	DNA primase activity
XcfCFBP4885P_RS01030	COG1295	ribonuclease BN
XcfCFBP4885P_RS01040	COG1610	YqeY-like protein
XcfCFBP4885P_RS01050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP4885P_RS01055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP4885P_RS01065	COG2133	pyrroloquinoline quinone binding
XcfCFBP4885P_RS01085	COG0531	amino acid
XcfCFBP4885P_RS01095	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP4885P_RS01105	COG3023	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP4885P_RS01150	COG5383	Protein conserved in bacteria
XcfCFBP4885P_RS01170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP4885P_RS01175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS01180	COG1473	amidohydrolase
XcfCFBP4885P_RS01185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP4885P_RS01185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP4885P_RS01190	COG1652	LysM domain
XcfCFBP4885P_RS01210	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS01220	COG3328	transposase activity
XcfCFBP4885P_RS01230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP4885P_RS01235	COG3118	belongs to the thioredoxin family
XcfCFBP4885P_RS01240	COG0513	Belongs to the DEAD box helicase family
XcfCFBP4885P_RS01245	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP4885P_RS01250	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP4885P_RS01255	COG3437	response regulator, receiver
XcfCFBP4885P_RS01260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP4885P_RS01265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP4885P_RS01275	COG1252	NADH dehydrogenase
XcfCFBP4885P_RS01290	COG0625	glutathione transferase activity
XcfCFBP4885P_RS01295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcfCFBP4885P_RS01315	COG0534	Mate efflux family protein
XcfCFBP4885P_RS01320	COG0616	signal peptide processing
XcfCFBP4885P_RS01335	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS01350	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP4885P_RS01355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP4885P_RS01355	COG1754	DNA topoisomerase type I activity
XcfCFBP4885P_RS01375	COG0758	DNA mediated transformation
XcfCFBP4885P_RS01380	COG1652	LysM domain
XcfCFBP4885P_RS01385	COG0242	peptide deformylase activity
XcfCFBP4885P_RS01390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP4885P_RS01395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP4885P_RS01395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP4885P_RS01450	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP4885P_RS01455	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP4885P_RS01460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP4885P_RS01475	COG0582	viral genome integration into host DNA
XcfCFBP4885P_RS01495	COG3328	transposase activity
XcfCFBP4885P_RS01535	COG0024	Methionine aminopeptidase
XcfCFBP4885P_RS01545	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP4885P_RS01575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP4885P_RS01580	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS01610	COG0251	oxidation-reduction process
XcfCFBP4885P_RS01685	COG1063	alcohol dehydrogenase
XcfCFBP4885P_RS01700	COG1132	(ABC) transporter
XcfCFBP4885P_RS01720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP4885P_RS01725	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS01740	COG1294	oxidase, subunit
XcfCFBP4885P_RS01745	COG1271	oxidase subunit
XcfCFBP4885P_RS01760	COG2204	response regulator
XcfCFBP4885P_RS01795	COG3546	catalase activity
XcfCFBP4885P_RS01800	COG3685	Protein conserved in bacteria
XcfCFBP4885P_RS01825	COG2972	Histidine kinase
XcfCFBP4885P_RS01840	COG0531	amino acid
XcfCFBP4885P_RS01855	COG3590	peptidase
XcfCFBP4885P_RS01870	COG0667	Aldo Keto reductase
XcfCFBP4885P_RS01880	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS01890	COG3384	dioxygenase
XcfCFBP4885P_RS01900	COG1573	uracil-dna glycosylase
XcfCFBP4885P_RS01905	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP4885P_RS01915	COG0025	NhaP-type Na H and K H
XcfCFBP4885P_RS01920	COG1131	(ABC) transporter
XcfCFBP4885P_RS01925	COG0842	Transport permease protein
XcfCFBP4885P_RS01985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP4885P_RS01990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP4885P_RS02010	COG2202	Pas domain
XcfCFBP4885P_RS02010	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS02035	COG1187	pseudouridine synthase activity
XcfCFBP4885P_RS02070	COG5002	protein histidine kinase activity
XcfCFBP4885P_RS02070	COG2198	Histidine kinase
XcfCFBP4885P_RS02070	COG0784	Response regulator, receiver
XcfCFBP4885P_RS02080	COG1666	GTP binding
XcfCFBP4885P_RS02085	COG0697	spore germination
XcfCFBP4885P_RS02090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP4885P_RS02095	COG2011	ABC-type metal ion transport system permease component
XcfCFBP4885P_RS02135	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP4885P_RS02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP4885P_RS02165	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP4885P_RS02175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP4885P_RS02180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP4885P_RS02185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP4885P_RS02190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP4885P_RS02195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP4885P_RS02200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP4885P_RS02220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP4885P_RS02225	COG4191	Histidine kinase
XcfCFBP4885P_RS02240	COG0577	efflux transmembrane transporter activity
XcfCFBP4885P_RS02240	COG1136	(ABC) transporter
XcfCFBP4885P_RS02245	COG0577	efflux transmembrane transporter activity
XcfCFBP4885P_RS02250	COG1136	(ABC) transporter
XcfCFBP4885P_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS02260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP4885P_RS02310	COG0339	signal peptide processing
XcfCFBP4885P_RS02325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP4885P_RS02330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP4885P_RS02335	COG0546	phosphoglycolate phosphatase activity
XcfCFBP4885P_RS02345	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP4885P_RS02355	COG1956	GAF domain-containing protein
XcfCFBP4885P_RS02360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP4885P_RS02385	COG0720	synthase
XcfCFBP4885P_RS02390	COG3328	transposase activity
XcfCFBP4885P_RS02395	COG4771	TonB-dependent receptor
XcfCFBP4885P_RS02405	COG0513	Belongs to the DEAD box helicase family
XcfCFBP4885P_RS02420	COG0625	glutathione transferase activity
XcfCFBP4885P_RS02450	COG0626	cystathionine gamma-synthase activity
XcfCFBP4885P_RS02460	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS02480	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS02485	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcfCFBP4885P_RS02515	COG0463	Glycosyl transferase, family 2
XcfCFBP4885P_RS02530	COG2086	electron transfer activity
XcfCFBP4885P_RS02560	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP4885P_RS02560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP4885P_RS02565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP4885P_RS02595	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP4885P_RS02595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP4885P_RS02600	COG1127	ABC transporter
XcfCFBP4885P_RS02605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP4885P_RS02620	COG0442	prolyl-tRNA aminoacylation
XcfCFBP4885P_RS02630	COG1183	phosphatidylcholine synthase activity
XcfCFBP4885P_RS02665	COG0525	valine-tRNA ligase activity
XcfCFBP4885P_RS02680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP4885P_RS02690	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP4885P_RS02705	COG4974	Belongs to the 'phage' integrase family
XcfCFBP4885P_RS02720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP4885P_RS02735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP4885P_RS02735	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP4885P_RS02740	COG5295	Hep Hag repeat protein
XcfCFBP4885P_RS02745	COG1404	Belongs to the peptidase S8 family
XcfCFBP4885P_RS02750	COG5295	Hep Hag repeat protein
XcfCFBP4885P_RS02755	COG1404	Belongs to the peptidase S8 family
XcfCFBP4885P_RS02760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP4885P_RS02770	COG1459	type II secretion system
XcfCFBP4885P_RS02775	COG2165	general secretion pathway protein
XcfCFBP4885P_RS02780	COG4970	Tfp pilus assembly protein FimT
XcfCFBP4885P_RS02785	COG2165	general secretion pathway protein
XcfCFBP4885P_RS02790	COG4795	General secretion pathway protein
XcfCFBP4885P_RS02795	COG3156	type II secretion system protein K
XcfCFBP4885P_RS02800	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP4885P_RS02815	COG1450	Type ii and iii secretion system protein
XcfCFBP4885P_RS02825	COG2188	Transcriptional regulator
XcfCFBP4885P_RS02880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP4885P_RS02895	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS02900	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS02905	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP4885P_RS02910	COG0457	Tetratricopeptide repeat
XcfCFBP4885P_RS02935	COG0242	peptide deformylase activity
XcfCFBP4885P_RS02940	COG1307	EDD domain protein, DegV family
XcfCFBP4885P_RS02945	COG3039	Transposase
XcfCFBP4885P_RS02955	COG2373	Large extracellular alpha-helical protein
XcfCFBP4885P_RS02975	COG4953	penicillin-binding protein 1C
XcfCFBP4885P_RS02985	COG0678	peroxiredoxin activity
XcfCFBP4885P_RS03005	COG0330	HflC and HflK could
XcfCFBP4885P_RS03010	COG0330	HflC and HflK could
XcfCFBP4885P_RS03020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP4885P_RS03030	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS03035	COG1309	transcriptional regulator
XcfCFBP4885P_RS03080	COG3328	transposase activity
XcfCFBP4885P_RS03090	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XcfCFBP4885P_RS03125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP4885P_RS03135	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP4885P_RS03140	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS03150	COG3537	Alpha-1,2-mannosidase
XcfCFBP4885P_RS03155	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS03170	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP4885P_RS03205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP4885P_RS03210	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP4885P_RS03215	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP4885P_RS03250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP4885P_RS03265	COG0587	DNA-directed DNA polymerase activity
XcfCFBP4885P_RS03280	COG1297	OPT oligopeptide transporter protein
XcfCFBP4885P_RS03295	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP4885P_RS03295	COG1506	peptidase
XcfCFBP4885P_RS03310	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP4885P_RS03310	COG2207	Transcriptional regulator
XcfCFBP4885P_RS03340	COG0753	catalase activity
XcfCFBP4885P_RS03345	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP4885P_RS03355	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP4885P_RS03355	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP4885P_RS03360	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS03375	COG2194	sulfuric ester hydrolase activity
XcfCFBP4885P_RS03390	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS03395	COG0642	Histidine kinase
XcfCFBP4885P_RS03405	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP4885P_RS03410	COG2894	cell division
XcfCFBP4885P_RS03415	COG0850	regulation of cytokinetic process
XcfCFBP4885P_RS03430	COG4585	Histidine kinase
XcfCFBP4885P_RS03435	COG2197	response regulator
XcfCFBP4885P_RS03450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP4885P_RS03480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP4885P_RS03490	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP4885P_RS03510	COG1946	Acyl-CoA thioesterase
XcfCFBP4885P_RS03525	COG0824	Thioesterase
XcfCFBP4885P_RS03530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP4885P_RS03535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP4885P_RS03540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP4885P_RS03545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP4885P_RS03550	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP4885P_RS03560	COG0196	riboflavin kinase activity
XcfCFBP4885P_RS03565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP4885P_RS03570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP4885P_RS03575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP4885P_RS03610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP4885P_RS03615	COG1845	cytochrome c oxidase, subunit III
XcfCFBP4885P_RS03620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP4885P_RS03635	COG3152	Membrane
XcfCFBP4885P_RS03645	COG2207	Transcriptional regulator
XcfCFBP4885P_RS03650	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP4885P_RS03660	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP4885P_RS03665	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP4885P_RS03670	COG2172	sigma factor antagonist activity
XcfCFBP4885P_RS03695	COG4771	TonB-dependent receptor
XcfCFBP4885P_RS03705	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP4885P_RS03715	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS03725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP4885P_RS03730	COG4999	Histidine kinase
XcfCFBP4885P_RS03730	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS03730	COG3850	Histidine kinase
XcfCFBP4885P_RS03730	COG3437	response regulator, receiver
XcfCFBP4885P_RS03735	COG0784	Response regulator, receiver
XcfCFBP4885P_RS03735	COG4191	Histidine kinase
XcfCFBP4885P_RS03760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP4885P_RS03765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP4885P_RS03780	COG0228	four-way junction DNA binding
XcfCFBP4885P_RS03785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP4885P_RS03790	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP4885P_RS03795	COG0335	large ribosomal subunit rRNA binding
XcfCFBP4885P_RS03800	COG0534	Mate efflux family protein
XcfCFBP4885P_RS03825	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP4885P_RS03835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP4885P_RS03845	COG3328	transposase activity
XcfCFBP4885P_RS03895	COG3328	transposase activity
XcfCFBP4885P_RS03915	COG2003	Belongs to the UPF0758 family
XcfCFBP4885P_RS04005	COG3039	Transposase
XcfCFBP4885P_RS04015	COG3328	transposase activity
XcfCFBP4885P_RS04040	COG3250	beta-galactosidase activity
XcfCFBP4885P_RS04045	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP4885P_RS04065	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS04070	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS04095	COG3039	Transposase
XcfCFBP4885P_RS04100	COG3039	Transposase
XcfCFBP4885P_RS04110	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP4885P_RS04110	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS04125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP4885P_RS04130	COG0481	GTPase activity
XcfCFBP4885P_RS04145	COG0571	ribonuclease III activity
XcfCFBP4885P_RS04150	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP4885P_RS04155	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP4885P_RS04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP4885P_RS04170	COG2954	triphosphatase activity
XcfCFBP4885P_RS04175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP4885P_RS04180	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP4885P_RS04185	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP4885P_RS04190	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP4885P_RS04195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP4885P_RS04200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP4885P_RS04205	COG1278	Cold shock
XcfCFBP4885P_RS04210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP4885P_RS04220	COG1201	RNA secondary structure unwinding
XcfCFBP4885P_RS04225	COG1793	dna ligase
XcfCFBP4885P_RS04235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP4885P_RS04235	COG1793	dna ligase
XcfCFBP4885P_RS04265	COG0183	Belongs to the thiolase family
XcfCFBP4885P_RS04290	COG1451	nucleotide metabolic process
XcfCFBP4885P_RS04295	COG5487	UPF0391 membrane protein
XcfCFBP4885P_RS04305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP4885P_RS04320	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP4885P_RS04325	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP4885P_RS04335	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP4885P_RS04345	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP4885P_RS04350	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS04385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP4885P_RS04385	COG0392	lysyltransferase activity
XcfCFBP4885P_RS04395	COG0251	oxidation-reduction process
XcfCFBP4885P_RS04400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP4885P_RS04415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP4885P_RS04440	COG1595	DNA-templated transcription, initiation
XcfCFBP4885P_RS04465	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP4885P_RS04475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP4885P_RS04475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP4885P_RS04490	COG3039	Transposase
XcfCFBP4885P_RS04500	COG1131	(ABC) transporter
XcfCFBP4885P_RS04505	COG0346	lactoylglutathione lyase activity
XcfCFBP4885P_RS04510	COG0833	amino acid
XcfCFBP4885P_RS04515	COG2040	homocysteine
XcfCFBP4885P_RS04525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP4885P_RS04550	COG1695	Transcriptional regulator
XcfCFBP4885P_RS04570	COG1981	membrane
XcfCFBP4885P_RS04585	COG0825	malonyl-CoA metabolic process
XcfCFBP4885P_RS04600	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP4885P_RS04605	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP4885P_RS04610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP4885P_RS04615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP4885P_RS04630	COG0750	zinc metalloprotease
XcfCFBP4885P_RS04635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP4885P_RS04640	COG0575	Belongs to the CDS family
XcfCFBP4885P_RS04645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP4885P_RS04650	COG0233	cytoplasmic translational termination
XcfCFBP4885P_RS04655	COG0528	UMP kinase activity
XcfCFBP4885P_RS04665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP4885P_RS04670	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP4885P_RS04710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP4885P_RS04720	COG1393	Belongs to the ArsC family
XcfCFBP4885P_RS04725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP4885P_RS04730	COG0367	asparagine synthase
XcfCFBP4885P_RS04740	COG4774	siderophore transport
XcfCFBP4885P_RS04755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP4885P_RS04780	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP4885P_RS04785	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS04835	COG0339	signal peptide processing
XcfCFBP4885P_RS04845	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP4885P_RS04905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP4885P_RS04910	COG0084	hydrolase, TatD family'
XcfCFBP4885P_RS04925	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS04945	COG0367	asparagine synthase
XcfCFBP4885P_RS04955	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP4885P_RS04960	COG0415	Belongs to the DNA photolyase family
XcfCFBP4885P_RS04970	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS05015	COG3706	GGDEF domain
XcfCFBP4885P_RS05030	COG3328	transposase activity
XcfCFBP4885P_RS05035	COG0582	viral genome integration into host DNA
XcfCFBP4885P_RS05050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP4885P_RS05065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP4885P_RS05075	COG0497	DNA recombination
XcfCFBP4885P_RS05080	COG1420	regulation of RNA biosynthetic process
XcfCFBP4885P_RS05085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP4885P_RS05090	COG0443	Heat shock 70 kDa protein
XcfCFBP4885P_RS05095	COG0484	heat shock protein binding
XcfCFBP4885P_RS05105	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP4885P_RS05135	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS05140	COG1132	(ABC) transporter
XcfCFBP4885P_RS05165	COG0567	Dehydrogenase, E1 component
XcfCFBP4885P_RS05175	COG2850	peptidyl-arginine hydroxylation
XcfCFBP4885P_RS05200	COG1253	flavin adenine dinucleotide binding
XcfCFBP4885P_RS05235	COG1131	(ABC) transporter
XcfCFBP4885P_RS05240	COG1725	Transcriptional regulator
XcfCFBP4885P_RS05250	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP4885P_RS05265	COG2900	Belongs to the SlyX family
XcfCFBP4885P_RS05290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP4885P_RS05300	COG0646	methionine synthase
XcfCFBP4885P_RS05300	COG1410	methionine synthase
XcfCFBP4885P_RS05305	COG0646	methionine synthase
XcfCFBP4885P_RS05305	COG1410	methionine synthase
XcfCFBP4885P_RS05310	COG2226	methyltransferase
XcfCFBP4885P_RS05315	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS05320	COG3328	transposase activity
XcfCFBP4885P_RS05330	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS05350	COG0557	exoribonuclease II activity
XcfCFBP4885P_RS05360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP4885P_RS05370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP4885P_RS05380	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP4885P_RS05385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP4885P_RS05390	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP4885P_RS05395	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP4885P_RS05400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP4885P_RS05425	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP4885P_RS05430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP4885P_RS05440	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS05450	COG0494	nUDIX hydrolase
XcfCFBP4885P_RS05485	COG0488	(ABC) transporter
XcfCFBP4885P_RS05495	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP4885P_RS05495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP4885P_RS05500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP4885P_RS05525	COG2925	Exonuclease
XcfCFBP4885P_RS05530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP4885P_RS05535	COG3844	kynureninase activity
XcfCFBP4885P_RS05545	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP4885P_RS05550	COG0288	reversible hydration of carbon dioxide
XcfCFBP4885P_RS05600	COG3039	Transposase
XcfCFBP4885P_RS05605	COG3328	transposase activity
XcfCFBP4885P_RS05640	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP4885P_RS05650	COG0316	Belongs to the HesB IscA family
XcfCFBP4885P_RS05655	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP4885P_RS05660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP4885P_RS05665	COG0359	binds to the 23S rRNA
XcfCFBP4885P_RS05680	COG3115	cell septum assembly
XcfCFBP4885P_RS05690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP4885P_RS05695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcfCFBP4885P_RS05700	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP4885P_RS05715	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP4885P_RS05725	COG4993	Dehydrogenase
XcfCFBP4885P_RS05740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP4885P_RS05750	COG2986	histidine ammonia-lyase
XcfCFBP4885P_RS05755	COG1228	amidohydrolase
XcfCFBP4885P_RS05795	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP4885P_RS05800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP4885P_RS05805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP4885P_RS05810	COG1605	Chorismate mutase
XcfCFBP4885P_RS05810	COG0077	Prephenate dehydratase
XcfCFBP4885P_RS05815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP4885P_RS05830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP4885P_RS05835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP4885P_RS05840	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS05855	COG3039	Transposase
XcfCFBP4885P_RS05870	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS05905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP4885P_RS05910	COG4191	Histidine kinase
XcfCFBP4885P_RS05910	COG0784	Response regulator, receiver
XcfCFBP4885P_RS05925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP4885P_RS05935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP4885P_RS05945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP4885P_RS05960	COG1595	DNA-templated transcription, initiation
XcfCFBP4885P_RS06015	COG2244	polysaccharide biosynthetic process
XcfCFBP4885P_RS06045	COG2264	protein methyltransferase activity
XcfCFBP4885P_RS06070	COG1136	(ABC) transporter
XcfCFBP4885P_RS06080	COG2271	Major facilitator Superfamily
XcfCFBP4885P_RS06090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP4885P_RS06100	COG1253	flavin adenine dinucleotide binding
XcfCFBP4885P_RS06115	COG0306	phosphate transporter
XcfCFBP4885P_RS06145	COG0504	CTP synthase activity
XcfCFBP4885P_RS06160	COG0148	phosphopyruvate hydratase activity
XcfCFBP4885P_RS06165	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP4885P_RS06170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP4885P_RS06175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP4885P_RS06180	COG0585	pseudouridine synthase activity
XcfCFBP4885P_RS06185	COG2840	Smr protein MutS2
XcfCFBP4885P_RS06190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP4885P_RS06195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP4885P_RS06200	COG1238	metal cluster binding
XcfCFBP4885P_RS06215	COG1534	Rna-binding protein
XcfCFBP4885P_RS06220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP4885P_RS06230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP4885P_RS06235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP4885P_RS06245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP4885P_RS06250	COG1546	Belongs to the CinA family
XcfCFBP4885P_RS06260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP4885P_RS06265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP4885P_RS06275	COG2137	regulation of response to DNA damage stimulus
XcfCFBP4885P_RS06280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP4885P_RS06285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP4885P_RS06305	COG1741	Belongs to the pirin family
XcfCFBP4885P_RS06310	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS06335	COG0351	phosphomethylpyrimidine kinase
XcfCFBP4885P_RS06350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP4885P_RS06355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP4885P_RS06370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP4885P_RS06380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP4885P_RS06385	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP4885P_RS06395	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP4885P_RS06400	COG0800	Aldolase
XcfCFBP4885P_RS06440	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP4885P_RS06450	COG1070	Carbohydrate kinase
XcfCFBP4885P_RS06455	COG2115	Belongs to the xylose isomerase family
XcfCFBP4885P_RS06460	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS06475	COG3328	transposase activity
XcfCFBP4885P_RS06485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP4885P_RS06490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP4885P_RS06505	COG0494	nUDIX hydrolase
XcfCFBP4885P_RS06510	COG0433	COG0433 Predicted ATPase
XcfCFBP4885P_RS06525	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP4885P_RS06535	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP4885P_RS06540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP4885P_RS06545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP4885P_RS06550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP4885P_RS06565	COG0101	tRNA pseudouridine synthase activity
XcfCFBP4885P_RS06570	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP4885P_RS06580	COG0133	tryptophan synthase activity
XcfCFBP4885P_RS06590	COG0159	tryptophan synthase activity
XcfCFBP4885P_RS06595	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP4885P_RS06600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP4885P_RS06630	COG0300	oxidoreductase activity
XcfCFBP4885P_RS06635	COG0149	triose-phosphate isomerase activity
XcfCFBP4885P_RS06650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP4885P_RS06655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP4885P_RS06660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP4885P_RS06665	COG0649	NAD binding
XcfCFBP4885P_RS06670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP4885P_RS06675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP4885P_RS06685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP4885P_RS06690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP4885P_RS06715	COG1007	ATP synthesis coupled electron transport
XcfCFBP4885P_RS06725	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP4885P_RS06730	COG0195	Participates in both transcription termination and antitermination
XcfCFBP4885P_RS06735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP4885P_RS06740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP4885P_RS06745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP4885P_RS06750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP4885P_RS06755	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP4885P_RS06790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP4885P_RS06800	COG2095	MarC family integral membrane protein
XcfCFBP4885P_RS06815	COG1611	Belongs to the LOG family
XcfCFBP4885P_RS06860	COG3328	transposase activity
XcfCFBP4885P_RS06870	COG0556	nucleotide-excision repair
XcfCFBP4885P_RS06885	COG3505	Type IV secretory pathway VirD4
XcfCFBP4885P_RS06905	COG2948	multi-organism process
XcfCFBP4885P_RS06925	COG3702	type iv secretory pathway
XcfCFBP4885P_RS06985	COG3328	transposase activity
XcfCFBP4885P_RS06995	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP4885P_RS07005	COG2190	(PTS) system
XcfCFBP4885P_RS07005	COG2211	Major facilitator Superfamily
XcfCFBP4885P_RS07020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP4885P_RS07025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP4885P_RS07040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP4885P_RS07045	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP4885P_RS07045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP4885P_RS07095	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS07100	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS07110	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS07135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP4885P_RS07140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP4885P_RS07145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP4885P_RS07165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP4885P_RS07175	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS07185	COG3040	lipid binding
XcfCFBP4885P_RS07195	COG0582	viral genome integration into host DNA
XcfCFBP4885P_RS07205	COG3039	Transposase
XcfCFBP4885P_RS07215	COG3039	Transposase
XcfCFBP4885P_RS07220	COG3039	Transposase
XcfCFBP4885P_RS07235	COG3039	Transposase
XcfCFBP4885P_RS07250	COG0322	excinuclease ABC activity
XcfCFBP4885P_RS07270	COG0784	Response regulator, receiver
XcfCFBP4885P_RS07270	COG4191	Histidine kinase
XcfCFBP4885P_RS07275	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP4885P_RS07280	COG1194	a g-specific adenine glycosylase
XcfCFBP4885P_RS07290	COG0552	protein localization to endoplasmic reticulum
XcfCFBP4885P_RS07300	COG3938	Belongs to the proline racemase family
XcfCFBP4885P_RS07305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP4885P_RS07320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP4885P_RS07330	COG0006	proline dipeptidase activity
XcfCFBP4885P_RS07345	COG0531	amino acid
XcfCFBP4885P_RS07375	COG3039	Transposase
XcfCFBP4885P_RS07445	COG3039	Transposase
XcfCFBP4885P_RS07455	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP4885P_RS07460	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP4885P_RS07465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP4885P_RS07480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP4885P_RS07485	COG0405	Gamma-glutamyltransferase
XcfCFBP4885P_RS07490	COG3291	Pkd domain containing protein
XcfCFBP4885P_RS07495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP4885P_RS07535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP4885P_RS07540	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP4885P_RS07545	COG1862	Preprotein translocase
XcfCFBP4885P_RS07555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP4885P_RS07580	COG3039	Transposase
XcfCFBP4885P_RS07585	COG3039	Transposase
XcfCFBP4885P_RS07600	COG3328	transposase activity
XcfCFBP4885P_RS07635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP4885P_RS07635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP4885P_RS07640	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP4885P_RS07645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP4885P_RS07645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP4885P_RS07650	COG1609	Transcriptional regulator
XcfCFBP4885P_RS07655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP4885P_RS07660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS07670	COG2902	Dehydrogenase
XcfCFBP4885P_RS07680	COG0604	alcohol dehydrogenase
XcfCFBP4885P_RS07680	COG3321	synthase
XcfCFBP4885P_RS07690	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP4885P_RS07700	COG0300	oxidoreductase activity
XcfCFBP4885P_RS07710	COG3039	Transposase
XcfCFBP4885P_RS07725	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS07740	COG5002	protein histidine kinase activity
XcfCFBP4885P_RS07740	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS07740	COG0784	Response regulator, receiver
XcfCFBP4885P_RS07745	COG2733	membrane
XcfCFBP4885P_RS07755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP4885P_RS07770	COG2223	nitrite transmembrane transporter activity
XcfCFBP4885P_RS07775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP4885P_RS07780	COG0243	molybdopterin cofactor binding
XcfCFBP4885P_RS07795	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS07800	COG2703	oxygen carrier activity
XcfCFBP4885P_RS07810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP4885P_RS07815	COG0174	glutamine synthetase
XcfCFBP4885P_RS07820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcfCFBP4885P_RS07835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP4885P_RS07865	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP4885P_RS07870	COG1177	transmembrane transport
XcfCFBP4885P_RS07875	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP4885P_RS07890	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP4885P_RS07900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP4885P_RS07910	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP4885P_RS07915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP4885P_RS07930	COG0741	lytic transglycosylase activity
XcfCFBP4885P_RS07940	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP4885P_RS07945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP4885P_RS07950	COG2857	Cytochrome c1
XcfCFBP4885P_RS07955	COG0625	glutathione transferase activity
XcfCFBP4885P_RS07960	COG2969	positive regulation of protein catabolic process
XcfCFBP4885P_RS07985	COG1201	RNA secondary structure unwinding
XcfCFBP4885P_RS07990	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP4885P_RS07995	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS08000	COG0835	chemotaxis
XcfCFBP4885P_RS08045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP4885P_RS08060	COG1570	exodeoxyribonuclease VII activity
XcfCFBP4885P_RS08065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP4885P_RS08070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP4885P_RS08070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP4885P_RS08075	COG0802	atpase or kinase
XcfCFBP4885P_RS08080	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP4885P_RS08085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP4885P_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS08115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP4885P_RS08120	COG0501	Belongs to the peptidase M48B family
XcfCFBP4885P_RS08130	COG2081	HI0933 family
XcfCFBP4885P_RS08135	COG4681	YaeQ
XcfCFBP4885P_RS08145	COG0625	glutathione transferase activity
XcfCFBP4885P_RS08155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP4885P_RS08160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP4885P_RS08165	COG0513	Belongs to the DEAD box helicase family
XcfCFBP4885P_RS08170	COG0488	(ABC) transporter
XcfCFBP4885P_RS08190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP4885P_RS08195	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP4885P_RS08210	COG3300	MHYT domain
XcfCFBP4885P_RS08210	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS08215	COG1509	lysine 2,3-aminomutase activity
XcfCFBP4885P_RS08220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP4885P_RS08230	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP4885P_RS08235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP4885P_RS08260	COG3328	transposase activity
XcfCFBP4885P_RS08305	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP4885P_RS08325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP4885P_RS08330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP4885P_RS08345	COG2166	iron-sulfur cluster assembly
XcfCFBP4885P_RS08350	COG0215	cysteine-tRNA ligase activity
XcfCFBP4885P_RS08360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP4885P_RS08365	COG0137	argininosuccinate synthase activity
XcfCFBP4885P_RS08375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP4885P_RS08380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP4885P_RS08390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP4885P_RS08395	COG0165	Argininosuccinate lyase
XcfCFBP4885P_RS08405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP4885P_RS08410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP4885P_RS08440	COG1294	oxidase, subunit
XcfCFBP4885P_RS08450	COG4988	ABC transporter
XcfCFBP4885P_RS08455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP4885P_RS08460	COG1278	Cold shock
XcfCFBP4885P_RS08465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP4885P_RS08485	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP4885P_RS08490	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP4885P_RS08510	COG4133	protoheme IX ABC transporter activity
XcfCFBP4885P_RS08515	COG0436	Aminotransferase
XcfCFBP4885P_RS08540	COG1187	pseudouridine synthase activity
XcfCFBP4885P_RS08545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP4885P_RS08550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP4885P_RS08555	COG2350	Protein conserved in bacteria
XcfCFBP4885P_RS08585	COG1175	transmembrane transport
XcfCFBP4885P_RS08590	COG0395	ABC-type sugar transport system, permease component
XcfCFBP4885P_RS08615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP4885P_RS08620	COG2957	Belongs to the agmatine deiminase family
XcfCFBP4885P_RS08640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP4885P_RS08645	COG0539	negative regulation of cytoplasmic translation
XcfCFBP4885P_RS08650	COG0776	regulation of translation
XcfCFBP4885P_RS08660	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP4885P_RS08665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP4885P_RS08675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP4885P_RS08685	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP4885P_RS08685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP4885P_RS08700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP4885P_RS08710	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP4885P_RS08710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP4885P_RS08720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP4885P_RS08725	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS08740	COG2197	response regulator
XcfCFBP4885P_RS08755	COG1335	isochorismatase
XcfCFBP4885P_RS08770	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS08785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP4885P_RS08785	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP4885P_RS08805	COG3685	Protein conserved in bacteria
XcfCFBP4885P_RS08825	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS08835	COG4566	intracellular signal transduction
XcfCFBP4885P_RS08875	COG3275	phosphorelay sensor kinase activity
XcfCFBP4885P_RS08880	COG3279	Response regulator of the LytR AlgR family
XcfCFBP4885P_RS08920	COG3920	Histidine kinase
XcfCFBP4885P_RS08945	COG3220	belongs to the UPF0276 family
XcfCFBP4885P_RS08955	COG3328	transposase activity
XcfCFBP4885P_RS08965	COG3328	transposase activity
XcfCFBP4885P_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS09045	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP4885P_RS09050	COG1073	alpha beta
XcfCFBP4885P_RS09050	COG2226	methyltransferase
XcfCFBP4885P_RS09100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP4885P_RS09100	COG0316	Belongs to the HesB IscA family
XcfCFBP4885P_RS09105	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP4885P_RS09115	COG0428	transporter
XcfCFBP4885P_RS09120	COG3064	Membrane
XcfCFBP4885P_RS09130	COG1530	ribonuclease E activity
XcfCFBP4885P_RS09140	COG1054	Belongs to the UPF0176 family
XcfCFBP4885P_RS09160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP4885P_RS09185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP4885P_RS09190	COG0322	excinuclease ABC activity
XcfCFBP4885P_RS09200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP4885P_RS09205	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP4885P_RS09210	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP4885P_RS09215	COG1132	(ABC) transporter
XcfCFBP4885P_RS09220	COG0848	biopolymer transport protein
XcfCFBP4885P_RS09225	COG0811	peptide transport
XcfCFBP4885P_RS09240	COG1136	(ABC) transporter
XcfCFBP4885P_RS09245	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP4885P_RS09255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP4885P_RS09260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP4885P_RS09275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP4885P_RS09290	COG0354	folic acid binding
XcfCFBP4885P_RS09300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP4885P_RS09305	COG0837	glucose binding
XcfCFBP4885P_RS09310	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP4885P_RS09315	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP4885P_RS09320	COG0800	Aldolase
XcfCFBP4885P_RS09385	COG0784	Response regulator, receiver
XcfCFBP4885P_RS09385	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS09390	COG2183	response to ionizing radiation
XcfCFBP4885P_RS09400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP4885P_RS09400	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP4885P_RS09415	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP4885P_RS09425	COG1183	phosphatidylcholine synthase activity
XcfCFBP4885P_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS09445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP4885P_RS09455	COG0668	transmembrane transport
XcfCFBP4885P_RS09460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcfCFBP4885P_RS09475	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP4885P_RS09505	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP4885P_RS09510	COG0303	'Molybdopterin
XcfCFBP4885P_RS09520	COG0708	Exodeoxyribonuclease III
XcfCFBP4885P_RS09555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP4885P_RS09560	COG0303	'Molybdopterin
XcfCFBP4885P_RS09565	COG1160	GTP binding
XcfCFBP4885P_RS09570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP4885P_RS09580	COG1426	Protein conserved in bacteria
XcfCFBP4885P_RS09590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP4885P_RS09605	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP4885P_RS09605	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS09610	COG0183	Belongs to the thiolase family
XcfCFBP4885P_RS09620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP4885P_RS09625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP4885P_RS09635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP4885P_RS09645	COG1674	ftsk spoiiie
XcfCFBP4885P_RS09650	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP4885P_RS09660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP4885P_RS09670	COG0542	response to heat
XcfCFBP4885P_RS09685	COG0482	sulfurtransferase activity
XcfCFBP4885P_RS09690	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP4885P_RS09720	COG5002	protein histidine kinase activity
XcfCFBP4885P_RS09740	COG3039	Transposase
XcfCFBP4885P_RS09755	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP4885P_RS09805	COG3190	flagellar
XcfCFBP4885P_RS09830	COG1684	flagellar biosynthetic protein fliR
XcfCFBP4885P_RS09860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP4885P_RS09895	COG2198	Histidine kinase
XcfCFBP4885P_RS09895	COG0643	Histidine kinase
XcfCFBP4885P_RS09895	COG0784	Response regulator, receiver
XcfCFBP4885P_RS09900	COG3328	transposase activity
XcfCFBP4885P_RS09920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP4885P_RS09925	COG1360	Flagellar Motor Protein
XcfCFBP4885P_RS09935	COG0835	chemotaxis
XcfCFBP4885P_RS09945	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS09955	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS09975	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS09980	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS09990	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10000	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10005	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10010	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10015	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10050	COG0835	chemotaxis
XcfCFBP4885P_RS10065	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS10075	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP4885P_RS10080	COG2201	protein-glutamate methylesterase activity
XcfCFBP4885P_RS10090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP4885P_RS10120	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP4885P_RS10125	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS10130	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS10130	COG2198	Histidine kinase
XcfCFBP4885P_RS10130	COG0784	Response regulator, receiver
XcfCFBP4885P_RS10135	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS10135	COG2198	Histidine kinase
XcfCFBP4885P_RS10135	COG0784	Response regulator, receiver
XcfCFBP4885P_RS10145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP4885P_RS10155	COG3279	Response regulator of the LytR AlgR family
XcfCFBP4885P_RS10165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP4885P_RS10175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP4885P_RS10180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP4885P_RS10190	COG0505	Belongs to the CarA family
XcfCFBP4885P_RS10195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP4885P_RS10200	COG2258	MOSC domain
XcfCFBP4885P_RS10205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP4885P_RS10250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP4885P_RS10270	COG0277	FAD linked oxidase domain protein
XcfCFBP4885P_RS10275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP4885P_RS10285	COG0531	amino acid
XcfCFBP4885P_RS10290	COG0531	amino acid
XcfCFBP4885P_RS10295	COG0235	Class ii aldolase
XcfCFBP4885P_RS10300	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP4885P_RS10305	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP4885P_RS10320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP4885P_RS10320	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP4885P_RS10325	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP4885P_RS10330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP4885P_RS10335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP4885P_RS10340	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP4885P_RS10340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP4885P_RS10345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP4885P_RS10350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP4885P_RS10355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP4885P_RS10365	COG0124	histidyl-tRNA synthetase
XcfCFBP4885P_RS10370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP4885P_RS10410	COG3328	transposase activity
XcfCFBP4885P_RS10425	COG3039	Transposase
XcfCFBP4885P_RS10435	COG3210	domain, Protein
XcfCFBP4885P_RS10460	COG3039	Transposase
XcfCFBP4885P_RS10465	COG3039	Transposase
XcfCFBP4885P_RS10470	COG3328	transposase activity
XcfCFBP4885P_RS10490	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP4885P_RS10490	COG0726	polysaccharide deacetylase
XcfCFBP4885P_RS10495	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP4885P_RS10525	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP4885P_RS10530	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP4885P_RS10535	COG0697	spore germination
XcfCFBP4885P_RS10545	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP4885P_RS10565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP4885P_RS10575	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP4885P_RS10580	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP4885P_RS10585	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS10585	COG4251	negative regulation of phosphorylation
XcfCFBP4885P_RS10585	COG3706	GGDEF domain
XcfCFBP4885P_RS10585	COG2203	Gaf domain
XcfCFBP4885P_RS10600	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP4885P_RS10625	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP4885P_RS10630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP4885P_RS10635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP4885P_RS10655	COG1469	GTP cyclohydrolase I activity
XcfCFBP4885P_RS10660	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP4885P_RS10685	COG3328	transposase activity
XcfCFBP4885P_RS10735	COG0717	Belongs to the dCTP deaminase family
XcfCFBP4885P_RS10745	COG0489	protein tyrosine kinase activity
XcfCFBP4885P_RS10760	COG3039	Transposase
XcfCFBP4885P_RS10770	COG3590	peptidase
XcfCFBP4885P_RS10775	COG3590	peptidase
XcfCFBP4885P_RS10795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP4885P_RS10800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP4885P_RS10805	COG2311	Membrane
XcfCFBP4885P_RS10810	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP4885P_RS10815	COG0791	NLP P60 protein
XcfCFBP4885P_RS10820	COG0791	NLP P60 protein
XcfCFBP4885P_RS10830	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP4885P_RS10835	COG1301	dicarboxylic acid transport
XcfCFBP4885P_RS10840	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP4885P_RS10850	COG0037	tRNA processing
XcfCFBP4885P_RS10855	COG1722	exodeoxyribonuclease VII activity
XcfCFBP4885P_RS10860	COG0142	geranyltranstransferase activity
XcfCFBP4885P_RS10865	COG4104	PAAR repeat-containing protein
XcfCFBP4885P_RS10875	COG0312	modulator of DNA gyrase
XcfCFBP4885P_RS10880	COG3028	Belongs to the UPF0307 family
XcfCFBP4885P_RS10885	COG0312	modulator of DNA gyrase
XcfCFBP4885P_RS10895	COG3164	Protein of unknown function
XcfCFBP4885P_RS10905	COG0424	maF-like protein
XcfCFBP4885P_RS10910	COG2968	Membrane
XcfCFBP4885P_RS10925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP4885P_RS10940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP4885P_RS10955	COG0495	leucyl-tRNA aminoacylation
XcfCFBP4885P_RS10965	COG3118	belongs to the thioredoxin family
XcfCFBP4885P_RS11005	COG2155	Conserved Protein
XcfCFBP4885P_RS11050	COG1132	(ABC) transporter
XcfCFBP4885P_RS11075	COG1538	Outer membrane efflux protein
XcfCFBP4885P_RS11080	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS11085	COG5002	protein histidine kinase activity
XcfCFBP4885P_RS11085	COG5000	phosphorelay sensor kinase activity
XcfCFBP4885P_RS11090	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP4885P_RS11100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP4885P_RS11120	COG1187	pseudouridine synthase activity
XcfCFBP4885P_RS11125	COG5002	protein histidine kinase activity
XcfCFBP4885P_RS11125	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS11135	COG1595	DNA-templated transcription, initiation
XcfCFBP4885P_RS11240	COG0667	Aldo Keto reductase
XcfCFBP4885P_RS11245	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS11250	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS11260	COG2207	Transcriptional regulator
XcfCFBP4885P_RS11270	COG1309	transcriptional regulator
XcfCFBP4885P_RS11280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP4885P_RS11295	COG0735	belongs to the Fur family
XcfCFBP4885P_RS11300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP4885P_RS11325	COG4452	Inner membrane protein CreD
XcfCFBP4885P_RS11340	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS11345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP4885P_RS11355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP4885P_RS11365	COG2198	Histidine kinase
XcfCFBP4885P_RS11365	COG0643	Histidine kinase
XcfCFBP4885P_RS11370	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS11375	COG0835	chemotaxis
XcfCFBP4885P_RS11380	COG2200	EAL domain
XcfCFBP4885P_RS11380	COG2202	Pas domain
XcfCFBP4885P_RS11380	COG2199	diguanylate cyclase activity
XcfCFBP4885P_RS11385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP4885P_RS11390	COG2201	protein-glutamate methylesterase activity
XcfCFBP4885P_RS11395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP4885P_RS11400	COG3590	peptidase
XcfCFBP4885P_RS11410	COG0588	phosphoglycerate mutase activity
XcfCFBP4885P_RS11415	COG1515	deoxyribonuclease V activity
XcfCFBP4885P_RS11425	COG3328	transposase activity
XcfCFBP4885P_RS11430	COG1741	Belongs to the pirin family
XcfCFBP4885P_RS11445	COG1741	Belongs to the pirin family
XcfCFBP4885P_RS11450	COG1966	Carbon starvation protein
XcfCFBP4885P_RS11455	COG2879	small protein
XcfCFBP4885P_RS11500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP4885P_RS11505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP4885P_RS11510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP4885P_RS11515	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP4885P_RS11520	COG3321	synthase
XcfCFBP4885P_RS11520	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS11520	COG0604	alcohol dehydrogenase
XcfCFBP4885P_RS11525	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS11525	COG2203	Gaf domain
XcfCFBP4885P_RS11525	COG3706	GGDEF domain
XcfCFBP4885P_RS11525	COG4251	negative regulation of phosphorylation
XcfCFBP4885P_RS11530	COG0629	single-stranded DNA binding
XcfCFBP4885P_RS11535	COG0142	geranyltranstransferase activity
XcfCFBP4885P_RS11550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP4885P_RS11565	COG0527	aspartate kinase activity
XcfCFBP4885P_RS11570	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP4885P_RS11575	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP4885P_RS11585	COG1764	response to oxidative stress
XcfCFBP4885P_RS11590	COG0540	Belongs to the ATCase OTCase family
XcfCFBP4885P_RS11595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP4885P_RS11600	COG1678	Uncharacterized ACR, COG1678
XcfCFBP4885P_RS11610	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP4885P_RS11635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP4885P_RS11650	COG0739	heme binding
XcfCFBP4885P_RS11670	COG0693	protein deglycase activity
XcfCFBP4885P_RS11680	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP4885P_RS11685	COG0719	Fe-S assembly protein
XcfCFBP4885P_RS11690	COG0396	ATPase activity
XcfCFBP4885P_RS11695	COG0719	Fe-S assembly protein
XcfCFBP4885P_RS11700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP4885P_RS11710	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP4885P_RS11715	COG4774	siderophore transport
XcfCFBP4885P_RS11720	COG3128	pkhd-type hydroxylase
XcfCFBP4885P_RS11745	COG1477	protein flavinylation
XcfCFBP4885P_RS11750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP4885P_RS11760	COG1555	photosystem II stabilization
XcfCFBP4885P_RS11775	COG3178	'Phosphotransferase
XcfCFBP4885P_RS11780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP4885P_RS11795	COG0628	permease
XcfCFBP4885P_RS11805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP4885P_RS11815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP4885P_RS11835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP4885P_RS11840	COG0271	Belongs to the BolA IbaG family
XcfCFBP4885P_RS11850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP4885P_RS11860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP4885P_RS11865	COG1137	ATPase activity
XcfCFBP4885P_RS11880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP4885P_RS11885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP4885P_RS11890	COG1660	Displays ATPase and GTPase activities
XcfCFBP4885P_RS11900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP4885P_RS11905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP4885P_RS11915	COG2239	Acts as a magnesium transporter
XcfCFBP4885P_RS11925	COG1294	oxidase, subunit
XcfCFBP4885P_RS11930	COG1271	oxidase subunit
XcfCFBP4885P_RS11940	COG1113	amino acid transport
XcfCFBP4885P_RS11950	COG3328	transposase activity
XcfCFBP4885P_RS11975	COG2197	response regulator
XcfCFBP4885P_RS11980	COG0531	amino acid
XcfCFBP4885P_RS12085	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS12100	COG0754	glutathionylspermidine amidase activity
XcfCFBP4885P_RS12125	COG1842	Phage shock protein A
XcfCFBP4885P_RS12135	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP4885P_RS12140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP4885P_RS12145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP4885P_RS12155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP4885P_RS12160	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS12180	COG2198	Histidine kinase
XcfCFBP4885P_RS12180	COG0784	Response regulator, receiver
XcfCFBP4885P_RS12180	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS12185	COG2353	YceI-like domain
XcfCFBP4885P_RS12205	COG1760	l-serine dehydratase
XcfCFBP4885P_RS12220	COG0460	homoserine dehydrogenase
XcfCFBP4885P_RS12220	COG0527	aspartate kinase activity
XcfCFBP4885P_RS12225	COG0626	cystathionine gamma-synthase activity
XcfCFBP4885P_RS12230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP4885P_RS12235	COG0739	heme binding
XcfCFBP4885P_RS12240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP4885P_RS12245	COG1272	protein, Hemolysin III
XcfCFBP4885P_RS12250	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP4885P_RS12255	COG0517	IMP dehydrogenase activity
XcfCFBP4885P_RS12255	COG0516	GMP reductase activity
XcfCFBP4885P_RS12260	COG0463	Glycosyl transferase, family 2
XcfCFBP4885P_RS12265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP4885P_RS12270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP4885P_RS12280	COG4771	TonB-dependent receptor
XcfCFBP4885P_RS12290	COG3039	Transposase
XcfCFBP4885P_RS12295	COG1309	transcriptional regulator
XcfCFBP4885P_RS12305	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS12340	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP4885P_RS12345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP4885P_RS12365	COG1742	UPF0060 membrane protein
XcfCFBP4885P_RS12370	COG3956	TIGRFAM MazG family protein
XcfCFBP4885P_RS12375	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP4885P_RS12380	COG0494	nUDIX hydrolase
XcfCFBP4885P_RS12390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP4885P_RS12395	COG0837	glucose binding
XcfCFBP4885P_RS12410	COG3858	chitin binding
XcfCFBP4885P_RS12410	COG1388	LysM domain
XcfCFBP4885P_RS12425	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP4885P_RS12445	COG0531	amino acid
XcfCFBP4885P_RS12455	COG1486	melibiose metabolic process
XcfCFBP4885P_RS12465	COG3537	Alpha-1,2-mannosidase
XcfCFBP4885P_RS12505	COG3142	Participates in the control of copper homeostasis
XcfCFBP4885P_RS12510	COG1446	asparaginase
XcfCFBP4885P_RS12535	COG2198	Histidine kinase
XcfCFBP4885P_RS12535	COG0643	Histidine kinase
XcfCFBP4885P_RS12535	COG0784	Response regulator, receiver
XcfCFBP4885P_RS12540	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS12545	COG0835	chemotaxis
XcfCFBP4885P_RS12560	COG0189	ligase activity
XcfCFBP4885P_RS12570	COG1397	ADP-ribosylglycohydrolase
XcfCFBP4885P_RS12580	COG1199	ATP-dependent helicase activity
XcfCFBP4885P_RS12590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP4885P_RS12595	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS12610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP4885P_RS12620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP4885P_RS12625	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP4885P_RS12630	COG0535	radical SAM domain protein
XcfCFBP4885P_RS12635	COG0535	radical SAM domain protein
XcfCFBP4885P_RS12650	COG0837	glucose binding
XcfCFBP4885P_RS12660	COG1643	Atp-dependent helicase
XcfCFBP4885P_RS12665	COG0783	Belongs to the Dps family
XcfCFBP4885P_RS12670	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP4885P_RS12710	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS12730	COG3920	Histidine kinase
XcfCFBP4885P_RS12735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP4885P_RS12745	COG0602	queuosine metabolic process
XcfCFBP4885P_RS12755	COG2885	chlorophyll binding
XcfCFBP4885P_RS12760	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP4885P_RS12770	COG0848	biopolymer transport protein
XcfCFBP4885P_RS12780	COG0824	Thioesterase
XcfCFBP4885P_RS12785	COG2255	four-way junction helicase activity
XcfCFBP4885P_RS12795	COG3158	transport of potassium into the cell
XcfCFBP4885P_RS12800	COG0632	four-way junction helicase activity
XcfCFBP4885P_RS12805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP4885P_RS12810	COG0217	transcriptional regulatory protein
XcfCFBP4885P_RS12825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP4885P_RS12840	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS12880	COG0488	(ABC) transporter
XcfCFBP4885P_RS12920	COG4651	solute:proton antiporter activity
XcfCFBP4885P_RS12920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP4885P_RS12930	COG4772	TonB-dependent receptor
XcfCFBP4885P_RS12940	COG4264	IucA IucC family
XcfCFBP4885P_RS12955	COG0019	diaminopimelate decarboxylase activity
XcfCFBP4885P_RS12980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP4885P_RS12990	COG1492	cobalamin metabolic process
XcfCFBP4885P_RS13000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP4885P_RS13025	COG4206	TonB-dependent receptor
XcfCFBP4885P_RS13030	COG0542	response to heat
XcfCFBP4885P_RS13035	COG1116	anion transmembrane transporter activity
XcfCFBP4885P_RS13040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP4885P_RS13045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP4885P_RS13050	COG0667	Aldo Keto reductase
XcfCFBP4885P_RS13055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP4885P_RS13060	COG4771	TonB-dependent receptor
XcfCFBP4885P_RS13065	COG2827	Endonuclease containing a URI domain
XcfCFBP4885P_RS13105	COG1877	trehalose-phosphatase activity
XcfCFBP4885P_RS13110	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP4885P_RS13130	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS13135	COG3011	Protein conserved in bacteria
XcfCFBP4885P_RS13150	COG0564	pseudouridine synthase activity
XcfCFBP4885P_RS13155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP4885P_RS13165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP4885P_RS13165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP4885P_RS13180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP4885P_RS13185	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP4885P_RS13220	COG1459	type II secretion system
XcfCFBP4885P_RS13225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP4885P_RS13230	COG0237	dephospho-CoA kinase activity
XcfCFBP4885P_RS13240	COG3328	transposase activity
XcfCFBP4885P_RS13255	COG3039	Transposase
XcfCFBP4885P_RS13270	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS13280	COG0189	ligase activity
XcfCFBP4885P_RS13310	COG3328	transposase activity
XcfCFBP4885P_RS13375	COG1396	sequence-specific DNA binding
XcfCFBP4885P_RS13385	COG3328	transposase activity
XcfCFBP4885P_RS13395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP4885P_RS13400	COG1061	Type III restriction enzyme res subunit
XcfCFBP4885P_RS13405	COG1002	Type II restriction enzyme, methylase subunits
XcfCFBP4885P_RS13410	COG3328	transposase activity
XcfCFBP4885P_RS13500	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP4885P_RS13505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP4885P_RS13510	COG3273	potassium ion transport
XcfCFBP4885P_RS13510	COG0471	metal ion transport
XcfCFBP4885P_RS13535	COG1970	mechanosensitive ion channel activity
XcfCFBP4885P_RS13545	COG1609	Transcriptional regulator
XcfCFBP4885P_RS13555	COG3250	beta-galactosidase activity
XcfCFBP4885P_RS13560	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP4885P_RS13570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP4885P_RS13580	COG0308	aminopeptidase N
XcfCFBP4885P_RS13585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP4885P_RS13595	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP4885P_RS13595	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP4885P_RS13600	COG0175	sulfate reduction
XcfCFBP4885P_RS13605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP4885P_RS13610	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP4885P_RS13615	COG0175	sulfate reduction
XcfCFBP4885P_RS13640	COG0784	Response regulator, receiver
XcfCFBP4885P_RS13640	COG2198	Histidine kinase
XcfCFBP4885P_RS13640	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS13655	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS13660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP4885P_RS13660	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP4885P_RS13675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP4885P_RS13680	COG3588	fructose-bisphosphate aldolase
XcfCFBP4885P_RS13695	COG0469	pyruvate kinase activity
XcfCFBP4885P_RS13705	COG0126	phosphoglycerate kinase activity
XcfCFBP4885P_RS13730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP4885P_RS13745	COG3047	cAMP biosynthetic process
XcfCFBP4885P_RS13755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP4885P_RS13755	COG3453	Protein conserved in bacteria
XcfCFBP4885P_RS13760	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP4885P_RS13765	COG4149	molybdate abc transporter
XcfCFBP4885P_RS13770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP4885P_RS13805	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP4885P_RS13810	COG0739	heme binding
XcfCFBP4885P_RS13815	COG4773	Receptor
XcfCFBP4885P_RS13825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP4885P_RS13830	COG3039	Transposase
XcfCFBP4885P_RS13835	COG1301	dicarboxylic acid transport
XcfCFBP4885P_RS13850	COG2304	oxidoreductase activity
XcfCFBP4885P_RS13870	COG0714	Associated with various cellular activities
XcfCFBP4885P_RS13910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP4885P_RS13935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP4885P_RS13945	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP4885P_RS13960	COG2271	Major facilitator Superfamily
XcfCFBP4885P_RS13975	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS13980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP4885P_RS13995	COG1561	YicC-like family, N-terminal region
XcfCFBP4885P_RS14000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP4885P_RS14010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP4885P_RS14015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP4885P_RS14030	COG0006	proline dipeptidase activity
XcfCFBP4885P_RS14040	COG0006	proline dipeptidase activity
XcfCFBP4885P_RS14045	COG3079	Belongs to the UPF0149 family
XcfCFBP4885P_RS14065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP4885P_RS14075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP4885P_RS14085	COG2912	Transglutaminase-like superfamily
XcfCFBP4885P_RS14095	COG1773	rubredoxin
XcfCFBP4885P_RS14100	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP4885P_RS14120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP4885P_RS14135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP4885P_RS14170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP4885P_RS14175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP4885P_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS14190	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP4885P_RS14195	COG3781	membrane
XcfCFBP4885P_RS14205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP4885P_RS14210	COG0563	adenylate kinase activity
XcfCFBP4885P_RS14225	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP4885P_RS14235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP4885P_RS14260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP4885P_RS14275	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS14280	COG0405	Gamma-glutamyltransferase
XcfCFBP4885P_RS14285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP4885P_RS14305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP4885P_RS14310	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP4885P_RS14315	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP4885P_RS14325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP4885P_RS14345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP4885P_RS14350	COG1538	Outer membrane efflux protein
XcfCFBP4885P_RS14355	COG1519	Transferase
XcfCFBP4885P_RS14360	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP4885P_RS14385	COG0281	malic enzyme
XcfCFBP4885P_RS14385	COG0280	phosphate acetyltransferase
XcfCFBP4885P_RS14390	COG1301	dicarboxylic acid transport
XcfCFBP4885P_RS14415	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS14420	COG0667	Aldo Keto reductase
XcfCFBP4885P_RS14435	COG2197	response regulator
XcfCFBP4885P_RS14445	COG0642	Histidine kinase
XcfCFBP4885P_RS14465	COG2851	Citrate transporter
XcfCFBP4885P_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS14475	COG1609	Transcriptional regulator
XcfCFBP4885P_RS14480	COG2211	Major facilitator Superfamily
XcfCFBP4885P_RS14510	COG1162	GTPase activity
XcfCFBP4885P_RS14515	COG0436	Aminotransferase
XcfCFBP4885P_RS14530	COG0726	polysaccharide deacetylase
XcfCFBP4885P_RS14535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP4885P_RS14550	COG3964	amidohydrolase
XcfCFBP4885P_RS14555	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP4885P_RS14575	COG3039	Transposase
XcfCFBP4885P_RS14615	COG3829	transcription factor binding
XcfCFBP4885P_RS14640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP4885P_RS14645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP4885P_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS14665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP4885P_RS14675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP4885P_RS14685	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP4885P_RS14690	COG0424	maF-like protein
XcfCFBP4885P_RS14715	COG0714	Associated with various cellular activities
XcfCFBP4885P_RS14735	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP4885P_RS14740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP4885P_RS14745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP4885P_RS14775	COG3328	transposase activity
XcfCFBP4885P_RS14800	COG3328	transposase activity
XcfCFBP4885P_RS14815	COG3039	Transposase
XcfCFBP4885P_RS14840	COG0314	molybdopterin synthase activity
XcfCFBP4885P_RS14845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP4885P_RS14850	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP4885P_RS14860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP4885P_RS14865	COG1234	tRNA 3'-trailer cleavage
XcfCFBP4885P_RS14870	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP4885P_RS14875	COG0859	PFAM glycosyl transferase family 9
XcfCFBP4885P_RS14890	COG0631	protein serine/threonine phosphatase activity
XcfCFBP4885P_RS14895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP4885P_RS14900	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP4885P_RS14910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP4885P_RS14925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP4885P_RS14955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP4885P_RS14965	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP4885P_RS15005	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP4885P_RS15020	COG4783	chaperone-mediated protein folding
XcfCFBP4885P_RS15035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP4885P_RS15045	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP4885P_RS15050	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP4885P_RS15055	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP4885P_RS15075	COG2833	Protein of unknown function (DUF455)
XcfCFBP4885P_RS15095	COG0285	dihydrofolate synthase activity
XcfCFBP4885P_RS15100	COG0406	alpha-ribazole phosphatase activity
XcfCFBP4885P_RS15130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP4885P_RS15135	COG4208	sulfate ABC transporter
XcfCFBP4885P_RS15140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP4885P_RS15150	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP4885P_RS15180	COG0604	alcohol dehydrogenase
XcfCFBP4885P_RS15185	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP4885P_RS15185	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP4885P_RS15200	COG0625	glutathione transferase activity
XcfCFBP4885P_RS15205	COG0039	L-malate dehydrogenase activity
XcfCFBP4885P_RS15210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP4885P_RS15215	COG1217	gtp-binding protein TYPA
XcfCFBP4885P_RS15225	COG0154	amidase activity
XcfCFBP4885P_RS15240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP4885P_RS15260	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP4885P_RS15265	COG0203	ribosomal protein L17
XcfCFBP4885P_RS15290	COG0201	protein transport
XcfCFBP4885P_RS15295	COG0200	Binds to the 23S rRNA
XcfCFBP4885P_RS15300	COG1841	ribosomal large subunit assembly
XcfCFBP4885P_RS15310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP4885P_RS15315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP4885P_RS15320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP4885P_RS15330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP4885P_RS15335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP4885P_RS15345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP4885P_RS15350	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP4885P_RS15355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP4885P_RS15360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP4885P_RS15370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP4885P_RS15375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP4885P_RS15380	COG0089	rRNA binding
XcfCFBP4885P_RS15385	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP4885P_RS15390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP4885P_RS15395	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP4885P_RS15400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP4885P_RS15405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP4885P_RS15410	COG0049	tRNA binding
XcfCFBP4885P_RS15415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP4885P_RS15420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP4885P_RS15425	COG0085	RNA polymerase activity
XcfCFBP4885P_RS15430	COG0222	ribosome binding
XcfCFBP4885P_RS15435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP4885P_RS15440	COG0081	regulation of translation
XcfCFBP4885P_RS15445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP4885P_RS15450	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP4885P_RS15465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP4885P_RS15485	COG0012	GTP binding
XcfCFBP4885P_RS15490	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP4885P_RS15495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP4885P_RS15500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP4885P_RS15510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP4885P_RS15515	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP4885P_RS15525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP4885P_RS15530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP4885P_RS15540	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP4885P_RS15555	COG1254	Belongs to the acylphosphatase family
XcfCFBP4885P_RS15560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP4885P_RS15565	COG1295	ribonuclease BN
XcfCFBP4885P_RS15590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP4885P_RS15595	COG1404	Belongs to the peptidase S8 family
XcfCFBP4885P_RS15600	COG1404	Belongs to the peptidase S8 family
XcfCFBP4885P_RS15605	COG1404	Belongs to the peptidase S8 family
XcfCFBP4885P_RS15610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP4885P_RS15655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP4885P_RS15670	COG3039	Transposase
XcfCFBP4885P_RS15690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP4885P_RS15690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP4885P_RS15710	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP4885P_RS15720	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP4885P_RS15725	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS15735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP4885P_RS15740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP4885P_RS15750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP4885P_RS15760	COG2197	response regulator
XcfCFBP4885P_RS15785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP4885P_RS15795	COG0697	spore germination
XcfCFBP4885P_RS15820	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP4885P_RS15835	COG3039	Transposase
XcfCFBP4885P_RS15860	COG1024	Enoyl-CoA hydratase
XcfCFBP4885P_RS15875	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS15880	COG3384	dioxygenase
XcfCFBP4885P_RS15910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP4885P_RS15915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP4885P_RS15930	COG2096	Adenosyltransferase
XcfCFBP4885P_RS15935	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP4885P_RS15950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP4885P_RS15955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP4885P_RS15960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP4885P_RS15965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP4885P_RS15970	COG2967	ApaG domain
XcfCFBP4885P_RS15975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP4885P_RS15985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP4885P_RS15995	COG0747	negative chemotaxis
XcfCFBP4885P_RS16015	COG0431	NADPH-dependent FMN reductase
XcfCFBP4885P_RS16020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP4885P_RS16030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP4885P_RS16035	COG1116	anion transmembrane transporter activity
XcfCFBP4885P_RS16045	COG3829	transcription factor binding
XcfCFBP4885P_RS16060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP4885P_RS16065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP4885P_RS16085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP4885P_RS16095	COG0642	Histidine kinase
XcfCFBP4885P_RS16110	COG4181	ATPase activity
XcfCFBP4885P_RS16120	COG2175	clavaminate synthase activity
XcfCFBP4885P_RS16130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP4885P_RS16135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP4885P_RS16155	COG4771	TonB-dependent receptor
XcfCFBP4885P_RS16165	COG0667	Aldo Keto reductase
XcfCFBP4885P_RS16175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP4885P_RS16180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP4885P_RS16190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP4885P_RS16195	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP4885P_RS16205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP4885P_RS16245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP4885P_RS16255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP4885P_RS16260	COG2226	methyltransferase
XcfCFBP4885P_RS16295	COG0366	Alpha amylase catalytic
XcfCFBP4885P_RS16320	COG0604	alcohol dehydrogenase
XcfCFBP4885P_RS16320	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS16320	COG3321	synthase
XcfCFBP4885P_RS16335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP4885P_RS16345	COG0494	nUDIX hydrolase
XcfCFBP4885P_RS16350	COG0653	protein targeting
XcfCFBP4885P_RS16355	COG0739	heme binding
XcfCFBP4885P_RS16365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP4885P_RS16380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP4885P_RS16385	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP4885P_RS16390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP4885P_RS16395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP4885P_RS16405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP4885P_RS16410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP4885P_RS16415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP4885P_RS16425	COG3116	cell division
XcfCFBP4885P_RS16430	COG0275	rRNA processing
XcfCFBP4885P_RS16460	COG0792	nuclease activity
XcfCFBP4885P_RS16465	COG1988	membrane-bound metal-dependent
XcfCFBP4885P_RS16470	COG0277	FAD linked oxidase domain protein
XcfCFBP4885P_RS16475	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS16480	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS16485	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP4885P_RS16490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP4885P_RS16495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP4885P_RS16525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP4885P_RS16530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP4885P_RS16535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP4885P_RS16555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP4885P_RS16555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP4885P_RS16565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP4885P_RS16570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP4885P_RS16580	COG0488	(ABC) transporter
XcfCFBP4885P_RS16600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP4885P_RS16615	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP4885P_RS16645	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS16670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP4885P_RS16685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP4885P_RS16700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP4885P_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP4885P_RS16710	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP4885P_RS16715	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP4885P_RS16730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP4885P_RS16735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP4885P_RS16740	COG1609	Transcriptional regulator
XcfCFBP4885P_RS16750	COG2188	Transcriptional regulator
XcfCFBP4885P_RS16765	COG3250	beta-galactosidase activity
XcfCFBP4885P_RS16795	COG4795	General secretion pathway protein
XcfCFBP4885P_RS16810	COG2165	general secretion pathway protein
XcfCFBP4885P_RS16815	COG1459	type II secretion system
XcfCFBP4885P_RS16875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP4885P_RS16880	COG4191	Histidine kinase
XcfCFBP4885P_RS16885	COG0784	Response regulator, receiver
XcfCFBP4885P_RS16890	COG4251	negative regulation of phosphorylation
XcfCFBP4885P_RS16895	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP4885P_RS16900	COG0673	inositol 2-dehydrogenase activity
XcfCFBP4885P_RS16905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP4885P_RS16940	COG1056	cytidyltransferase-related domain
XcfCFBP4885P_RS16940	COG1051	belongs to the nudix hydrolase family
XcfCFBP4885P_RS16965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP4885P_RS16970	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP4885P_RS16975	COG2921	Belongs to the UPF0250 family
XcfCFBP4885P_RS16985	COG1686	Belongs to the peptidase S11 family
XcfCFBP4885P_RS16995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP4885P_RS17000	COG2951	lytic endotransglycosylase activity
XcfCFBP4885P_RS17010	COG0772	Belongs to the SEDS family
XcfCFBP4885P_RS17025	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP4885P_RS17030	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP4885P_RS17035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP4885P_RS17040	COG3284	Transcriptional regulator
XcfCFBP4885P_RS17090	COG0308	aminopeptidase N
XcfCFBP4885P_RS17095	COG3300	MHYT domain
XcfCFBP4885P_RS17095	COG5001	Diguanylate cyclase
XcfCFBP4885P_RS17100	COG2226	methyltransferase
XcfCFBP4885P_RS17125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP4885P_RS17130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP4885P_RS17135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP4885P_RS17145	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP4885P_RS17155	COG2832	Protein of unknown function (DUF454)
XcfCFBP4885P_RS17165	COG0436	Aminotransferase
XcfCFBP4885P_RS17170	COG1505	serine-type exopeptidase activity
XcfCFBP4885P_RS17200	COG0181	hydroxymethylbilane synthase activity
XcfCFBP4885P_RS17210	COG3275	phosphorelay sensor kinase activity
XcfCFBP4885P_RS17220	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP4885P_RS17245	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP4885P_RS17250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP4885P_RS17250	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP4885P_RS17255	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS17305	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP4885P_RS17325	COG1113	amino acid transport
XcfCFBP4885P_RS17345	COG0697	spore germination
XcfCFBP4885P_RS17390	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP4885P_RS17390	COG1506	peptidase
XcfCFBP4885P_RS17425	COG0435	Glutathione S-transferase
XcfCFBP4885P_RS17435	COG4221	oxidoreductase activity
XcfCFBP4885P_RS17450	COG4221	oxidoreductase activity
XcfCFBP4885P_RS17485	COG3328	transposase activity
XcfCFBP4885P_RS17515	COG3039	Transposase
XcfCFBP4885P_RS17525	COG3328	transposase activity
XcfCFBP4885P_RS17575	COG1802	Transcriptional regulator
XcfCFBP4885P_RS17585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP4885P_RS17610	COG3052	prosthetic group binding
XcfCFBP4885P_RS17640	COG2353	YceI-like domain
XcfCFBP4885P_RS17645	COG0778	Nitroreductase
XcfCFBP4885P_RS17670	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP4885P_RS17675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP4885P_RS17685	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP4885P_RS17700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP4885P_RS17715	COG0459	protein refolding
XcfCFBP4885P_RS17725	COG2356	endonuclease I
XcfCFBP4885P_RS17735	COG1324	tolerance protein
XcfCFBP4885P_RS17745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP4885P_RS17750	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP4885P_RS17760	COG0439	Biotin carboxylase
XcfCFBP4885P_RS17780	COG2264	protein methyltransferase activity
XcfCFBP4885P_RS17805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP4885P_RS17810	COG4589	Belongs to the CDS family
XcfCFBP4885P_RS17835	COG2453	phosphatase
XcfCFBP4885P_RS17835	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP4885P_RS17845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP4885P_RS17850	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP4885P_RS17860	COG0151	Belongs to the GarS family
XcfCFBP4885P_RS17865	COG1289	transmembrane transporter activity
XcfCFBP4885P_RS17870	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS17880	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS17895	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP4885P_RS17910	COG0316	Belongs to the HesB IscA family
XcfCFBP4885P_RS17950	COG1051	belongs to the nudix hydrolase family
XcfCFBP4885P_RS17965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP4885P_RS17975	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP4885P_RS17985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP4885P_RS17990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP4885P_RS18000	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP4885P_RS18005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP4885P_RS18025	COG3039	Transposase
XcfCFBP4885P_RS18040	COG3039	Transposase
XcfCFBP4885P_RS18050	COG3039	Transposase
XcfCFBP4885P_RS18075	COG0456	acetyltransferase
XcfCFBP4885P_RS18090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP4885P_RS18095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP4885P_RS18120	COG2111	Na H antiporter
XcfCFBP4885P_RS18120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP4885P_RS18125	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP4885P_RS18130	COG0651	ATP synthesis coupled electron transport
XcfCFBP4885P_RS18140	COG2212	antiporter activity
XcfCFBP4885P_RS18145	COG1320	monovalent cation:proton antiporter activity
XcfCFBP4885P_RS18185	COG3104	oligopeptide transport
XcfCFBP4885P_RS18190	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP4885P_RS18200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP4885P_RS18215	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP4885P_RS18220	COG0513	Belongs to the DEAD box helicase family
XcfCFBP4885P_RS18230	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS18235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP4885P_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS18275	COG0702	epimerase
XcfCFBP4885P_RS18300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP4885P_RS18305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP4885P_RS18310	COG0297	glycogen (starch) synthase activity
XcfCFBP4885P_RS18320	COG2354	Protein conserved in bacteria
XcfCFBP4885P_RS18325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP4885P_RS18330	COG1368	sulfuric ester hydrolase activity
XcfCFBP4885P_RS18335	COG1511	domain protein
XcfCFBP4885P_RS18335	COG3264	Mechanosensitive ion channel
XcfCFBP4885P_RS18365	COG3039	Transposase
XcfCFBP4885P_RS18415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP4885P_RS18480	COG3039	Transposase
XcfCFBP4885P_RS18485	COG3039	Transposase
XcfCFBP4885P_RS18515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP4885P_RS18525	COG1040	competence protein
XcfCFBP4885P_RS18530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP4885P_RS18535	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP4885P_RS18545	COG2267	carboxylic ester hydrolase activity
XcfCFBP4885P_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS18580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP4885P_RS18590	COG0445	tRNA wobble uridine modification
XcfCFBP4885P_RS18600	COG0657	acetylesterase activity
XcfCFBP4885P_RS18610	COG1414	Transcriptional regulator
XcfCFBP4885P_RS18625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP4885P_RS18630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP4885P_RS18640	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP4885P_RS18645	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP4885P_RS18655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP4885P_RS18660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP4885P_RS18685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP4885P_RS18690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP4885P_RS18745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP4885P_RS18760	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP4885P_RS18770	COG3039	Transposase
XcfCFBP4885P_RS18780	COG3039	Transposase
XcfCFBP4885P_RS18785	COG3328	transposase activity
XcfCFBP4885P_RS18815	COG1733	regulation of RNA biosynthetic process
XcfCFBP4885P_RS18820	COG0702	epimerase
XcfCFBP4885P_RS18855	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS18860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP4885P_RS18865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP4885P_RS18885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS18890	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS18895	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS18915	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP4885P_RS18920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP4885P_RS18925	COG2267	carboxylic ester hydrolase activity
XcfCFBP4885P_RS18935	COG2814	Major facilitator Superfamily
XcfCFBP4885P_RS18940	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS18950	COG0084	hydrolase, TatD family'
XcfCFBP4885P_RS18975	COG2252	PERMEase
XcfCFBP4885P_RS19010	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS19020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP4885P_RS19040	COG2072	flavoprotein involved in K transport
XcfCFBP4885P_RS19045	COG2351	hydroxyisourate hydrolase activity
XcfCFBP4885P_RS19050	COG4807	Protein conserved in bacteria
XcfCFBP4885P_RS19060	COG1643	Atp-dependent helicase
XcfCFBP4885P_RS19075	COG1187	pseudouridine synthase activity
XcfCFBP4885P_RS19090	COG2130	NADP-dependent
XcfCFBP4885P_RS19120	COG1764	response to oxidative stress
XcfCFBP4885P_RS19125	COG1846	Transcriptional regulator
XcfCFBP4885P_RS19130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP4885P_RS19140	COG0697	spore germination
XcfCFBP4885P_RS19205	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP4885P_RS19210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP4885P_RS19215	COG4770	biotin carboxylase activity
XcfCFBP4885P_RS19245	COG2224	Isocitrate lyase
XcfCFBP4885P_RS19250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP4885P_RS19255	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS19260	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP4885P_RS19295	COG0339	signal peptide processing
XcfCFBP4885P_RS19300	COG1446	asparaginase
XcfCFBP4885P_RS19320	COG0564	pseudouridine synthase activity
XcfCFBP4885P_RS19330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP4885P_RS19360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP4885P_RS19370	COG0745	RESPONSE REGULATOR receiver
XcfCFBP4885P_RS19375	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP4885P_RS19380	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP4885P_RS19385	COG0596	Alpha beta hydrolase
XcfCFBP4885P_RS19395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP4885P_RS19410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP4885P_RS19435	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS19440	COG0028	Belongs to the TPP enzyme family
XcfCFBP4885P_RS19455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP4885P_RS19460	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP4885P_RS19465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP4885P_RS19500	COG0183	Belongs to the thiolase family
XcfCFBP4885P_RS19515	COG3039	Transposase
XcfCFBP4885P_RS19525	COG2032	superoxide dismutase activity
XcfCFBP4885P_RS19530	COG2032	superoxide dismutase activity
XcfCFBP4885P_RS19535	COG2204	response regulator
XcfCFBP4885P_RS19540	COG3852	Histidine kinase
XcfCFBP4885P_RS19545	COG0004	ammonium transporteR
XcfCFBP4885P_RS19550	COG0347	Belongs to the P(II) protein family
XcfCFBP4885P_RS19555	COG0174	glutamine synthetase
XcfCFBP4885P_RS19565	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP4885P_RS19610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP4885P_RS19620	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP4885P_RS19625	COG0489	protein tyrosine kinase activity
XcfCFBP4885P_RS19635	COG3039	Transposase
XcfCFBP4885P_RS19645	COG3237	CsbD-like
XcfCFBP4885P_RS19660	COG3039	Transposase
XcfCFBP4885P_RS19705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP4885P_RS19715	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS19760	COG0714	Associated with various cellular activities
XcfCFBP4885P_RS19795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP4885P_RS19805	COG4772	TonB-dependent receptor
XcfCFBP4885P_RS19820	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP4885P_RS19845	COG1304	FMN binding
XcfCFBP4885P_RS19860	COG4585	Histidine kinase
XcfCFBP4885P_RS19865	COG2197	response regulator
XcfCFBP4885P_RS19885	COG3710	Transcriptional regulator
XcfCFBP4885P_RS19890	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP4885P_RS19915	COG3328	transposase activity
XcfCFBP4885P_RS19920	COG3328	transposase activity
XcfCFBP4885P_RS19940	COG3039	Transposase
XcfCFBP4885P_RS19945	COG3039	Transposase
XcfCFBP4885P_RS19970	COG0366	Alpha amylase catalytic
XcfCFBP4885P_RS19975	COG0366	Alpha amylase catalytic
XcfCFBP4885P_RS19980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP4885P_RS20000	COG2755	lipolytic protein G-D-S-L family
XcfCFBP4885P_RS20000	COG0657	acetylesterase activity
XcfCFBP4885P_RS20010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP4885P_RS20025	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP4885P_RS20030	COG1609	Transcriptional regulator
XcfCFBP4885P_RS20045	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP4885P_RS20050	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS20060	COG2755	lipolytic protein G-D-S-L family
XcfCFBP4885P_RS20070	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP4885P_RS20075	COG1522	sequence-specific DNA binding
XcfCFBP4885P_RS20085	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP4885P_RS20095	COG1119	ATPase activity
XcfCFBP4885P_RS20110	COG0517	IMP dehydrogenase activity
XcfCFBP4885P_RS20110	COG1125	glycine betaine transport
XcfCFBP4885P_RS20125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP4885P_RS20150	COG3039	Transposase
XcfCFBP4885P_RS20170	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP4885P_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS20220	COG1272	protein, Hemolysin III
XcfCFBP4885P_RS20225	COG1111	helicase
XcfCFBP4885P_RS20225	COG1205	dead DEAH box helicase
XcfCFBP4885P_RS20310	COG0070	glutamate synthase
XcfCFBP4885P_RS20310	COG0069	glutamate synthase activity
XcfCFBP4885P_RS20310	COG0067	glutamate synthase
XcfCFBP4885P_RS20315	COG0493	'glutamate synthase
XcfCFBP4885P_RS20320	COG1064	alcohol dehydrogenase
XcfCFBP4885P_RS20330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP4885P_RS20340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP4885P_RS20345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP4885P_RS20355	COG2234	aminopeptidase activity
XcfCFBP4885P_RS20365	COG4942	peptidase
XcfCFBP4885P_RS20370	COG0793	Belongs to the peptidase S41A family
XcfCFBP4885P_RS20420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP4885P_RS20430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP4885P_RS20470	COG0501	Belongs to the peptidase M48B family
XcfCFBP4885P_RS20480	COG0187	DNA topoisomerase II activity
XcfCFBP4885P_RS20485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP4885P_RS20510	COG0594	ribonuclease P activity
XcfCFBP4885P_RS20515	COG0706	membrane insertase activity
XcfCFBP4885P_RS20525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP4885P_RS20540	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP4885P_RS20550	COG0861	Integral membrane protein TerC family
XcfCFBP4885P_RS20560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP4885P_RS20575	COG2271	Major facilitator Superfamily
XcfCFBP4885P_RS20580	COG1929	Belongs to the glycerate kinase type-1 family
XcfCFBP4885P_RS20605	COG3537	Alpha-1,2-mannosidase
XcfCFBP4885P_RS20630	COG1192	Involved in chromosome partitioning
XcfCFBP4885P_RS20645	COG3039	Transposase
XcfCFBP4885P_RS20660	COG3328	transposase activity
XcfCFBP4885P_RS20685	COG4691	Plasmid stability protein
XcfCFBP4885P_RS20690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP4885P_RS20720	COG0840	transmembrane signaling receptor activity
XcfCFBP4885P_RS20780	COG3041	Addiction module toxin RelE StbE family
XcfCFBP4885P_RS20785	COG3077	Addiction module antitoxin, RelB DinJ family
XcfCFBP4885P_RS20830	COG0625	glutathione transferase activity
XcfCFBP4885P_RS20860	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP4885P_RS20870	COG2853	Lipoprotein
XcfCFBP4885P_RS20885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP4885P_RS20890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP4885P_RS20895	COG1127	ABC transporter
XcfCFBP4885P_RS20930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP4885P_RS20935	COG1074	ATP-dependent DNA helicase activity
XcfCFBP4885P_RS20940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP4885P_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS21010	COG3039	Transposase
XcfCFBP4885P_RS21020	COG3039	Transposase
XcfCFBP4885P_RS21025	COG3039	Transposase
XcfCFBP4885P_RS21030	COG3039	Transposase
XcfCFBP4885P_RS21050	COG0564	pseudouridine synthase activity
XcfCFBP4885P_RS21075	COG3328	transposase activity
XcfCFBP4885P_RS21095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP4885P_RS21105	COG4221	oxidoreductase activity
XcfCFBP4885P_RS21110	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS21120	COG0477	Major facilitator Superfamily
XcfCFBP4885P_RS21125	COG1289	transmembrane transporter activity
XcfCFBP4885P_RS21135	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP4885P_RS21150	COG0302	gtp cyclohydrolase
XcfCFBP4885P_RS21170	COG0730	response to heat
XcfCFBP4885P_RS21175	COG3012	SEC-C Motif Domain Protein
XcfCFBP4885P_RS21185	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP4885P_RS21205	COG3135	benzoate transporter
XcfCFBP4885P_RS21235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP4885P_RS21245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP4885P_RS21255	COG1435	thymidine kinase activity
XcfCFBP4885P_RS21260	COG0210	DNA helicase
XcfCFBP4885P_RS21285	COG3132	Protein of unknown function, DUF480
XcfCFBP4885P_RS21290	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP4885P_RS21295	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP4885P_RS21330	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP4885P_RS21360	COG2211	Major facilitator Superfamily
XcfCFBP4885P_RS21375	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP4885P_RS21390	COG1904	glucuronate isomerase
XcfCFBP4885P_RS21395	COG3250	beta-galactosidase activity
XcfCFBP4885P_RS21405	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP4885P_RS21485	COG0246	Mannitol dehydrogenase
XcfCFBP4885P_RS21490	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP4885P_RS21500	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP4885P_RS21520	COG2115	Belongs to the xylose isomerase family
XcfCFBP4885P_RS21530	COG0037	tRNA processing
XcfCFBP4885P_RS21535	COG2974	May be involved in recombination
XcfCFBP4885P_RS21555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP4885P_RS21565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP4885P_RS21570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP4885P_RS21575	COG0805	protein transport
XcfCFBP4885P_RS21585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP4885P_RS21585	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP4885P_RS21605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP4885P_RS21610	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP4885P_RS21635	COG3039	Transposase
XcfCFBP4885P_RS21645	COG3039	Transposase
XcfCFBP4885P_RS21650	COG3039	Transposase
XcfCFBP4885P_RS21660	COG0729	surface antigen
XcfCFBP4885P_RS21665	COG2911	Protein conserved in bacteria
XcfCFBP4885P_RS21690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP4885P_RS21700	COG3265	gluconokinase activity
XcfCFBP4885P_RS21705	COG2211	Major facilitator Superfamily
XcfCFBP4885P_RS21710	COG3459	Glycosyltransferase 36 associated
XcfCFBP4885P_RS21725	COG2205	protein histidine kinase activity
XcfCFBP4885P_RS21730	COG1971	Probably functions as a manganese efflux pump
XcfCFBP4885P_RS21735	COG1414	Transcriptional regulator
XcfCFBP4885P_RS21740	COG0738	Major facilitator superfamily
XcfCFBP4885P_RS21745	COG3254	rhamnose metabolic process
XcfCFBP4885P_RS21750	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP4885P_RS21755	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP4885P_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS21810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP4885P_RS21820	COG3162	membrane
XcfCFBP4885P_RS21825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP4885P_RS21840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP4885P_RS21850	COG1846	Transcriptional regulator
XcfCFBP4885P_RS21850	COG1940	carbohydrate kinase activity
XcfCFBP4885P_RS21855	COG0708	Exodeoxyribonuclease III
XcfCFBP4885P_RS21870	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP4885P_RS21880	COG3540	Alkaline phosphatase
XcfCFBP4885P_RS21885	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP4885P_RS21905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP4885P_RS21945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP4885P_RS21950	COG0583	DNA-binding transcription factor activity
XcfCFBP4885P_RS21955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP4885P_RS21965	COG0210	DNA helicase
XcfCFBP4885P_RS22035	COG3328	transposase activity
XcfCFBP4885P_RS22085	COG1595	DNA-templated transcription, initiation
XcfCFBP4885P_RS22150	COG0515	serine threonine protein kinase
XcfCFBP4885P_RS22190	COG0408	coproporphyrinogen oxidase activity
XcfCFBP4885P_RS22215	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP4885P_RS22215	COG1506	peptidase
XcfCFBP4885P_RS22215	COG4946	Tricorn protease homolog
XcfCFBP4885P_RS22245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP4885P_RS22260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP4885P_RS22295	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP4885P_RS22305	COG0463	Glycosyl transferase, family 2
XcfCFBP4885P_RS22315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP4885P_RS22320	COG3100	YcgL domain-containing protein
XcfCFBP4885P_RS22415	COG3328	transposase activity
XcfCFBP4885P_RS22425	COG4691	Plasmid stability protein
XcfCFBP4885P_RS22430	COG1487	ribonuclease activity
XcfCFBP4885P_RS22495	COG3039	Transposase
XcfCFBP4885P_RS22770	COG3328	transposase activity
XcfCFBP4885P_RS22805	COG3328	transposase activity
XcfCFBP4885P_RS22925	COG2951	lytic endotransglycosylase activity
XcfCFBP4885P_RS23055	COG1192	Involved in chromosome partitioning
XcfCFBP4885P_RS23235	COG3039	Transposase
XcfCFBP4885P_RS23260	COG0564	pseudouridine synthase activity