locus-tag	class	description
XcfCFBP6989P_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcfCFBP6989P_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6989P_RS00020	COG0187	DNA topoisomerase II activity
XcfCFBP6989P_RS00030	COG0501	Belongs to the peptidase M48B family
XcfCFBP6989P_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP6989P_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6989P_RS00120	COG0793	Belongs to the peptidase S41A family
XcfCFBP6989P_RS00125	COG4942	peptidase
XcfCFBP6989P_RS00135	COG2234	aminopeptidase activity
XcfCFBP6989P_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6989P_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6989P_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6989P_RS00160	COG1064	alcohol dehydrogenase
XcfCFBP6989P_RS00175	COG0493	'glutamate synthase
XcfCFBP6989P_RS00180	COG0069	glutamate synthase activity
XcfCFBP6989P_RS00180	COG0070	glutamate synthase
XcfCFBP6989P_RS00180	COG0067	glutamate synthase
XcfCFBP6989P_RS00260	COG1111	helicase
XcfCFBP6989P_RS00260	COG1205	dead DEAH box helicase
XcfCFBP6989P_RS00265	COG1272	protein, Hemolysin III
XcfCFBP6989P_RS00285	COG0300	oxidoreductase activity
XcfCFBP6989P_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS00310	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP6989P_RS00330	COG3237	CsbD-like
XcfCFBP6989P_RS00375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6989P_RS00380	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS00420	COG0714	Associated with various cellular activities
XcfCFBP6989P_RS00455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP6989P_RS00465	COG4772	TonB-dependent receptor
XcfCFBP6989P_RS00480	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6989P_RS00505	COG1304	FMN binding
XcfCFBP6989P_RS00515	COG4585	Histidine kinase
XcfCFBP6989P_RS00520	COG2197	response regulator
XcfCFBP6989P_RS00540	COG3710	Transcriptional regulator
XcfCFBP6989P_RS00545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP6989P_RS00705	COG0366	Alpha amylase catalytic
XcfCFBP6989P_RS00710	COG0366	Alpha amylase catalytic
XcfCFBP6989P_RS00715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6989P_RS00735	COG0657	acetylesterase activity
XcfCFBP6989P_RS00735	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6989P_RS00745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP6989P_RS00760	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6989P_RS00765	COG1609	Transcriptional regulator
XcfCFBP6989P_RS00770	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP6989P_RS00775	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS00785	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6989P_RS00795	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP6989P_RS00800	COG1522	sequence-specific DNA binding
XcfCFBP6989P_RS00810	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP6989P_RS00820	COG1119	ATPase activity
XcfCFBP6989P_RS00835	COG1125	glycine betaine transport
XcfCFBP6989P_RS00850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6989P_RS00880	COG0489	protein tyrosine kinase activity
XcfCFBP6989P_RS00885	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP6989P_RS00895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6989P_RS00940	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP6989P_RS00945	COG0174	glutamine synthetase
XcfCFBP6989P_RS00950	COG0347	Belongs to the P(II) protein family
XcfCFBP6989P_RS00955	COG0004	ammonium transporteR
XcfCFBP6989P_RS00965	COG3852	Histidine kinase
XcfCFBP6989P_RS00970	COG2204	response regulator
XcfCFBP6989P_RS00975	COG2032	superoxide dismutase activity
XcfCFBP6989P_RS00980	COG2032	superoxide dismutase activity
XcfCFBP6989P_RS00985	COG0346	lactoylglutathione lyase activity
XcfCFBP6989P_RS00995	COG0183	Belongs to the thiolase family
XcfCFBP6989P_RS01030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP6989P_RS01035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP6989P_RS01040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP6989P_RS01055	COG0028	Belongs to the TPP enzyme family
XcfCFBP6989P_RS01060	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS01085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP6989P_RS01100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6989P_RS01110	COG0596	Alpha beta hydrolase
XcfCFBP6989P_RS01115	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP6989P_RS01120	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6989P_RS01125	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS01135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6989P_RS01155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6989P_RS01165	COG0564	pseudouridine synthase activity
XcfCFBP6989P_RS01185	COG1446	asparaginase
XcfCFBP6989P_RS01190	COG0339	signal peptide processing
XcfCFBP6989P_RS01230	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6989P_RS01235	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS01240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP6989P_RS01245	COG2224	Isocitrate lyase
XcfCFBP6989P_RS01275	COG4770	biotin carboxylase activity
XcfCFBP6989P_RS01280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP6989P_RS01285	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS01350	COG0697	spore germination
XcfCFBP6989P_RS01360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP6989P_RS01365	COG1846	Transcriptional regulator
XcfCFBP6989P_RS01370	COG1764	response to oxidative stress
XcfCFBP6989P_RS01395	COG2130	NADP-dependent
XcfCFBP6989P_RS01410	COG1187	pseudouridine synthase activity
XcfCFBP6989P_RS01425	COG1643	Atp-dependent helicase
XcfCFBP6989P_RS01430	COG4807	Protein conserved in bacteria
XcfCFBP6989P_RS01435	COG2351	hydroxyisourate hydrolase activity
XcfCFBP6989P_RS01440	COG2072	flavoprotein involved in K transport
XcfCFBP6989P_RS01460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP6989P_RS01470	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS01505	COG2252	PERMEase
XcfCFBP6989P_RS01525	COG0084	hydrolase, TatD family'
XcfCFBP6989P_RS01535	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS01540	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS01550	COG2267	carboxylic ester hydrolase activity
XcfCFBP6989P_RS01555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP6989P_RS01560	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6989P_RS01580	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS01585	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS01590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS01615	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6989P_RS01620	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS01650	COG0702	epimerase
XcfCFBP6989P_RS01655	COG1733	regulation of RNA biosynthetic process
XcfCFBP6989P_RS01690	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6989P_RS01705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP6989P_RS01760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP6989P_RS01765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP6989P_RS01790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP6989P_RS01795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP6989P_RS01805	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6989P_RS01810	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6989P_RS01820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6989P_RS01825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP6989P_RS01835	COG1414	Transcriptional regulator
XcfCFBP6989P_RS01845	COG0657	acetylesterase activity
XcfCFBP6989P_RS01855	COG0445	tRNA wobble uridine modification
XcfCFBP6989P_RS01865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP6989P_RS01890	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS01895	COG2267	carboxylic ester hydrolase activity
XcfCFBP6989P_RS01905	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6989P_RS01910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP6989P_RS01915	COG1040	competence protein
XcfCFBP6989P_RS01920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6989P_RS01955	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6989P_RS02010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP6989P_RS02080	COG1511	domain protein
XcfCFBP6989P_RS02080	COG3264	Mechanosensitive ion channel
XcfCFBP6989P_RS02085	COG1368	sulfuric ester hydrolase activity
XcfCFBP6989P_RS02090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6989P_RS02095	COG2354	Protein conserved in bacteria
XcfCFBP6989P_RS02105	COG0297	glycogen (starch) synthase activity
XcfCFBP6989P_RS02110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6989P_RS02115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6989P_RS02140	COG0702	epimerase
XcfCFBP6989P_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS02175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS02190	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6989P_RS02195	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6989P_RS02210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP6989P_RS02220	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP6989P_RS02225	COG3104	oligopeptide transport
XcfCFBP6989P_RS02255	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcfCFBP6989P_RS02270	COG1320	monovalent cation:proton antiporter activity
XcfCFBP6989P_RS02275	COG2212	antiporter activity
XcfCFBP6989P_RS02285	COG0651	ATP synthesis coupled electron transport
XcfCFBP6989P_RS02290	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP6989P_RS02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6989P_RS02295	COG2111	Na H antiporter
XcfCFBP6989P_RS02320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP6989P_RS02325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP6989P_RS02340	COG0456	acetyltransferase
XcfCFBP6989P_RS02345	COG1597	lipid kinase activity
XcfCFBP6989P_RS02375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP6989P_RS02380	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP6989P_RS02390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6989P_RS02395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP6989P_RS02405	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP6989P_RS02415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP6989P_RS02430	COG1051	belongs to the nudix hydrolase family
XcfCFBP6989P_RS02470	COG0316	Belongs to the HesB IscA family
XcfCFBP6989P_RS02485	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6989P_RS02500	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS02510	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS02515	COG1289	transmembrane transporter activity
XcfCFBP6989P_RS02520	COG0151	Belongs to the GarS family
XcfCFBP6989P_RS02530	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP6989P_RS02535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6989P_RS02540	COG2267	carboxylic ester hydrolase activity
XcfCFBP6989P_RS02545	COG2453	phosphatase
XcfCFBP6989P_RS02545	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6989P_RS02570	COG4589	Belongs to the CDS family
XcfCFBP6989P_RS02575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP6989P_RS02600	COG2264	protein methyltransferase activity
XcfCFBP6989P_RS02615	COG0439	Biotin carboxylase
XcfCFBP6989P_RS02625	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP6989P_RS02630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP6989P_RS02640	COG1324	tolerance protein
XcfCFBP6989P_RS02650	COG2356	endonuclease I
XcfCFBP6989P_RS02660	COG0459	protein refolding
XcfCFBP6989P_RS02675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP6989P_RS02690	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6989P_RS02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP6989P_RS02705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6989P_RS02730	COG0778	Nitroreductase
XcfCFBP6989P_RS02735	COG2353	YceI-like domain
XcfCFBP6989P_RS02760	COG3052	prosthetic group binding
XcfCFBP6989P_RS02790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6989P_RS02800	COG1802	Transcriptional regulator
XcfCFBP6989P_RS02955	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6989P_RS02975	COG4221	oxidoreductase activity
XcfCFBP6989P_RS02990	COG4221	oxidoreductase activity
XcfCFBP6989P_RS03000	COG0435	Glutathione S-transferase
XcfCFBP6989P_RS03035	COG1506	peptidase
XcfCFBP6989P_RS03035	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6989P_RS03070	COG0697	spore germination
XcfCFBP6989P_RS03085	COG1113	amino acid transport
XcfCFBP6989P_RS03105	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP6989P_RS03150	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS03155	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6989P_RS03155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6989P_RS03160	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6989P_RS03175	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP6989P_RS03185	COG3275	phosphorelay sensor kinase activity
XcfCFBP6989P_RS03195	COG0181	hydroxymethylbilane synthase activity
XcfCFBP6989P_RS03220	COG1505	serine-type exopeptidase activity
XcfCFBP6989P_RS03225	COG0436	Aminotransferase
XcfCFBP6989P_RS03235	COG2832	Protein of unknown function (DUF454)
XcfCFBP6989P_RS03245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP6989P_RS03255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP6989P_RS03260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP6989P_RS03265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP6989P_RS03290	COG2226	methyltransferase
XcfCFBP6989P_RS03295	COG5001	Diguanylate cyclase
XcfCFBP6989P_RS03295	COG3300	MHYT domain
XcfCFBP6989P_RS03300	COG0308	aminopeptidase N
XcfCFBP6989P_RS03345	COG3284	Transcriptional regulator
XcfCFBP6989P_RS03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6989P_RS03355	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6989P_RS03360	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP6989P_RS03375	COG0772	Belongs to the SEDS family
XcfCFBP6989P_RS03385	COG2951	lytic endotransglycosylase activity
XcfCFBP6989P_RS03390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP6989P_RS03395	COG1686	Belongs to the peptidase S11 family
XcfCFBP6989P_RS03405	COG2921	Belongs to the UPF0250 family
XcfCFBP6989P_RS03410	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP6989P_RS03415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP6989P_RS03430	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS03440	COG1051	belongs to the nudix hydrolase family
XcfCFBP6989P_RS03440	COG1056	cytidyltransferase-related domain
XcfCFBP6989P_RS03475	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP6989P_RS03480	COG0673	inositol 2-dehydrogenase activity
XcfCFBP6989P_RS03485	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP6989P_RS03490	COG4251	negative regulation of phosphorylation
XcfCFBP6989P_RS03495	COG0784	Response regulator, receiver
XcfCFBP6989P_RS03500	COG4191	Histidine kinase
XcfCFBP6989P_RS03505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP6989P_RS03560	COG1459	type II secretion system
XcfCFBP6989P_RS03580	COG4795	General secretion pathway protein
XcfCFBP6989P_RS03610	COG3250	beta-galactosidase activity
XcfCFBP6989P_RS03625	COG2188	Transcriptional regulator
XcfCFBP6989P_RS03635	COG1609	Transcriptional regulator
XcfCFBP6989P_RS03640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6989P_RS03645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP6989P_RS03660	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP6989P_RS03665	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6989P_RS03670	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6989P_RS03675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP6989P_RS03690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6989P_RS03705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP6989P_RS03710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6989P_RS03725	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS03755	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP6989P_RS03770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6989P_RS03780	COG0697	spore germination
XcfCFBP6989P_RS03790	COG0488	(ABC) transporter
XcfCFBP6989P_RS03800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP6989P_RS03805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP6989P_RS03815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6989P_RS03815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6989P_RS03835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP6989P_RS03840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6989P_RS03845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP6989P_RS03865	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP6989P_RS03870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP6989P_RS03875	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP6989P_RS03880	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS03885	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS03900	COG0277	FAD linked oxidase domain protein
XcfCFBP6989P_RS03905	COG1988	membrane-bound metal-dependent
XcfCFBP6989P_RS03910	COG0792	nuclease activity
XcfCFBP6989P_RS03940	COG0275	rRNA processing
XcfCFBP6989P_RS03945	COG3116	cell division
XcfCFBP6989P_RS03955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP6989P_RS03960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP6989P_RS03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6989P_RS03975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP6989P_RS03980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6989P_RS03985	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6989P_RS03990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP6989P_RS04005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP6989P_RS04015	COG0739	heme binding
XcfCFBP6989P_RS04020	COG0653	protein targeting
XcfCFBP6989P_RS04025	COG0494	nUDIX hydrolase
XcfCFBP6989P_RS04035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP6989P_RS04045	COG0604	alcohol dehydrogenase
XcfCFBP6989P_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS04045	COG3321	synthase
XcfCFBP6989P_RS04065	COG0366	Alpha amylase catalytic
XcfCFBP6989P_RS04095	COG2226	methyltransferase
XcfCFBP6989P_RS04100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP6989P_RS04110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP6989P_RS04150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP6989P_RS04160	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6989P_RS04165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6989P_RS04175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6989P_RS04180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP6989P_RS04185	COG0667	Aldo Keto reductase
XcfCFBP6989P_RS04195	COG4771	TonB-dependent receptor
XcfCFBP6989P_RS04215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6989P_RS04220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP6989P_RS04230	COG2175	clavaminate synthase activity
XcfCFBP6989P_RS04240	COG4181	ATPase activity
XcfCFBP6989P_RS04255	COG0642	Histidine kinase
XcfCFBP6989P_RS04265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP6989P_RS04285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP6989P_RS04290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP6989P_RS04305	COG3829	transcription factor binding
XcfCFBP6989P_RS04315	COG1116	anion transmembrane transporter activity
XcfCFBP6989P_RS04320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6989P_RS04330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6989P_RS04335	COG0431	NADPH-dependent FMN reductase
XcfCFBP6989P_RS04360	COG0747	negative chemotaxis
XcfCFBP6989P_RS04370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP6989P_RS04380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP6989P_RS04385	COG2967	ApaG domain
XcfCFBP6989P_RS04390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP6989P_RS04395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP6989P_RS04400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6989P_RS04405	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP6989P_RS04415	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP6989P_RS04420	COG2096	Adenosyltransferase
XcfCFBP6989P_RS04435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6989P_RS04440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6989P_RS04470	COG3384	dioxygenase
XcfCFBP6989P_RS04475	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS04490	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS04520	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP6989P_RS04545	COG0697	spore germination
XcfCFBP6989P_RS04555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6989P_RS04580	COG2197	response regulator
XcfCFBP6989P_RS04590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP6989P_RS04600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP6989P_RS04605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6989P_RS04610	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS04615	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP6989P_RS04625	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6989P_RS04650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6989P_RS04650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6989P_RS04680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP6989P_RS04720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6989P_RS04730	COG1404	Belongs to the peptidase S8 family
XcfCFBP6989P_RS04735	COG1404	Belongs to the peptidase S8 family
XcfCFBP6989P_RS04740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP6989P_RS04765	COG1295	ribonuclease BN
XcfCFBP6989P_RS04770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6989P_RS04775	COG1254	Belongs to the acylphosphatase family
XcfCFBP6989P_RS04790	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP6989P_RS04800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP6989P_RS04805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP6989P_RS04815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP6989P_RS04820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP6989P_RS04830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP6989P_RS04835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP6989P_RS04840	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP6989P_RS04845	COG0012	GTP binding
XcfCFBP6989P_RS04865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6989P_RS04880	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP6989P_RS04885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP6989P_RS04890	COG0081	regulation of translation
XcfCFBP6989P_RS04895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP6989P_RS04900	COG0222	ribosome binding
XcfCFBP6989P_RS04905	COG0085	RNA polymerase activity
XcfCFBP6989P_RS04910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP6989P_RS04915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP6989P_RS04920	COG0049	tRNA binding
XcfCFBP6989P_RS04925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP6989P_RS04930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6989P_RS04935	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP6989P_RS04940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP6989P_RS04945	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP6989P_RS04950	COG0089	rRNA binding
XcfCFBP6989P_RS04955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP6989P_RS04960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP6989P_RS04970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP6989P_RS04975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP6989P_RS04980	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP6989P_RS04985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP6989P_RS04995	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP6989P_RS05000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP6989P_RS05005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XcfCFBP6989P_RS05010	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP6989P_RS05015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP6989P_RS05020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP6989P_RS05030	COG1841	ribosomal large subunit assembly
XcfCFBP6989P_RS05035	COG0200	Binds to the 23S rRNA
XcfCFBP6989P_RS05040	COG0201	protein transport
XcfCFBP6989P_RS05065	COG0203	ribosomal protein L17
XcfCFBP6989P_RS05070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP6989P_RS05085	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP6989P_RS05100	COG0154	amidase activity
XcfCFBP6989P_RS05110	COG1217	gtp-binding protein TYPA
XcfCFBP6989P_RS05115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP6989P_RS05120	COG0039	L-malate dehydrogenase activity
XcfCFBP6989P_RS05125	COG0625	glutathione transferase activity
XcfCFBP6989P_RS05135	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP6989P_RS05135	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6989P_RS05140	COG0604	alcohol dehydrogenase
XcfCFBP6989P_RS05165	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6989P_RS05170	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcfCFBP6989P_RS05175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP6989P_RS05180	COG4208	sulfate ABC transporter
XcfCFBP6989P_RS05185	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP6989P_RS05215	COG0406	alpha-ribazole phosphatase activity
XcfCFBP6989P_RS05220	COG0285	dihydrofolate synthase activity
XcfCFBP6989P_RS05240	COG2833	Protein of unknown function (DUF455)
XcfCFBP6989P_RS05245	COG3291	Pkd domain containing protein
XcfCFBP6989P_RS05255	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6989P_RS05260	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6989P_RS05265	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS05275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP6989P_RS05290	COG4783	chaperone-mediated protein folding
XcfCFBP6989P_RS05305	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6989P_RS05390	COG3328	transposase activity
XcfCFBP6989P_RS05520	COG3179	chitinase
XcfCFBP6989P_RS05565	COG4695	Portal protein
XcfCFBP6989P_RS05595	COG3328	transposase activity
XcfCFBP6989P_RS05610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6989P_RS05635	COG3852	Histidine kinase
XcfCFBP6989P_RS05645	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP6989P_RS05655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP6989P_RS05685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6989P_RS05695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6989P_RS05705	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP6989P_RS05710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6989P_RS05715	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6989P_RS05730	COG0859	PFAM glycosyl transferase family 9
XcfCFBP6989P_RS05735	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP6989P_RS05740	COG1234	tRNA 3'-trailer cleavage
XcfCFBP6989P_RS05745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP6989P_RS05755	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP6989P_RS05760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP6989P_RS05765	COG0314	molybdopterin synthase activity
XcfCFBP6989P_RS05785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP6989P_RS05790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP6989P_RS05795	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP6989P_RS05815	COG0714	Associated with various cellular activities
XcfCFBP6989P_RS05840	COG0424	maF-like protein
XcfCFBP6989P_RS05845	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP6989P_RS05855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6989P_RS05865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6989P_RS05885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP6989P_RS05890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP6989P_RS05915	COG3829	transcription factor binding
XcfCFBP6989P_RS05955	COG2373	Large extracellular alpha-helical protein
XcfCFBP6989P_RS05970	COG4953	penicillin-binding protein 1C
XcfCFBP6989P_RS05980	COG0678	peroxiredoxin activity
XcfCFBP6989P_RS06000	COG0330	HflC and HflK could
XcfCFBP6989P_RS06005	COG0330	HflC and HflK could
XcfCFBP6989P_RS06020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP6989P_RS06025	COG0308	aminopeptidase N
XcfCFBP6989P_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS06040	COG1309	transcriptional regulator
XcfCFBP6989P_RS06125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6989P_RS06135	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6989P_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS06145	COG3537	Alpha-1,2-mannosidase
XcfCFBP6989P_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS06165	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6989P_RS06195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6989P_RS06200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6989P_RS06205	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6989P_RS06240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6989P_RS06255	COG0587	DNA-directed DNA polymerase activity
XcfCFBP6989P_RS06270	COG1297	OPT oligopeptide transporter protein
XcfCFBP6989P_RS06285	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6989P_RS06285	COG1506	peptidase
XcfCFBP6989P_RS06300	COG2207	Transcriptional regulator
XcfCFBP6989P_RS06300	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP6989P_RS06320	COG0753	catalase activity
XcfCFBP6989P_RS06325	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP6989P_RS06335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6989P_RS06335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6989P_RS06340	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS06355	COG2194	sulfuric ester hydrolase activity
XcfCFBP6989P_RS06370	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS06375	COG0642	Histidine kinase
XcfCFBP6989P_RS06385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP6989P_RS06390	COG2894	cell division
XcfCFBP6989P_RS06395	COG0850	regulation of cytokinetic process
XcfCFBP6989P_RS06405	COG4585	Histidine kinase
XcfCFBP6989P_RS06410	COG2197	response regulator
XcfCFBP6989P_RS06425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP6989P_RS06450	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP6989P_RS06460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP6989P_RS06480	COG1946	Acyl-CoA thioesterase
XcfCFBP6989P_RS06495	COG0824	Thioesterase
XcfCFBP6989P_RS06500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP6989P_RS06505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP6989P_RS06510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP6989P_RS06515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP6989P_RS06520	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP6989P_RS06530	COG0196	riboflavin kinase activity
XcfCFBP6989P_RS06535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP6989P_RS06540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP6989P_RS06545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP6989P_RS06560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP6989P_RS06565	COG1845	cytochrome c oxidase, subunit III
XcfCFBP6989P_RS06570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP6989P_RS06585	COG3152	Membrane
XcfCFBP6989P_RS06595	COG2207	Transcriptional regulator
XcfCFBP6989P_RS06600	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6989P_RS06610	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6989P_RS06615	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6989P_RS06620	COG2172	sigma factor antagonist activity
XcfCFBP6989P_RS06645	COG4771	TonB-dependent receptor
XcfCFBP6989P_RS06655	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP6989P_RS06660	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS06670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6989P_RS06675	COG3437	response regulator, receiver
XcfCFBP6989P_RS06675	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS06675	COG3850	Histidine kinase
XcfCFBP6989P_RS06675	COG4999	Histidine kinase
XcfCFBP6989P_RS06680	COG4191	Histidine kinase
XcfCFBP6989P_RS06680	COG0784	Response regulator, receiver
XcfCFBP6989P_RS06710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6989P_RS06715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP6989P_RS06725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6989P_RS06730	COG0228	four-way junction DNA binding
XcfCFBP6989P_RS06735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP6989P_RS06740	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP6989P_RS06745	COG0335	large ribosomal subunit rRNA binding
XcfCFBP6989P_RS06750	COG0534	Mate efflux family protein
XcfCFBP6989P_RS06770	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP6989P_RS06780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP6989P_RS06815	COG3250	beta-galactosidase activity
XcfCFBP6989P_RS06820	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP6989P_RS06840	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS06845	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS06880	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS06880	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6989P_RS06895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6989P_RS06900	COG0481	GTPase activity
XcfCFBP6989P_RS06915	COG0571	ribonuclease III activity
XcfCFBP6989P_RS06920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP6989P_RS06925	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP6989P_RS06935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6989P_RS06940	COG2954	triphosphatase activity
XcfCFBP6989P_RS06945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP6989P_RS06950	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP6989P_RS06955	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP6989P_RS06960	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6989P_RS06965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP6989P_RS06970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP6989P_RS06975	COG1278	Cold shock
XcfCFBP6989P_RS06980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6989P_RS06990	COG1201	RNA secondary structure unwinding
XcfCFBP6989P_RS06995	COG1793	dna ligase
XcfCFBP6989P_RS07005	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6989P_RS07005	COG1793	dna ligase
XcfCFBP6989P_RS07040	COG0183	Belongs to the thiolase family
XcfCFBP6989P_RS07065	COG1451	nucleotide metabolic process
XcfCFBP6989P_RS07070	COG5487	UPF0391 membrane protein
XcfCFBP6989P_RS07080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6989P_RS07095	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6989P_RS07100	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6989P_RS07110	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP6989P_RS07115	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6989P_RS07120	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS07155	COG0392	lysyltransferase activity
XcfCFBP6989P_RS07155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP6989P_RS07165	COG0251	oxidation-reduction process
XcfCFBP6989P_RS07170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6989P_RS07185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6989P_RS07210	COG1595	DNA-templated transcription, initiation
XcfCFBP6989P_RS07225	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP6989P_RS07235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6989P_RS07235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6989P_RS07250	COG1131	(ABC) transporter
XcfCFBP6989P_RS07255	COG0346	lactoylglutathione lyase activity
XcfCFBP6989P_RS07260	COG0833	amino acid
XcfCFBP6989P_RS07265	COG2040	homocysteine
XcfCFBP6989P_RS07275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6989P_RS07295	COG1695	Transcriptional regulator
XcfCFBP6989P_RS07315	COG1981	membrane
XcfCFBP6989P_RS07330	COG0825	malonyl-CoA metabolic process
XcfCFBP6989P_RS07345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6989P_RS07350	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6989P_RS07355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6989P_RS07360	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6989P_RS07375	COG0750	zinc metalloprotease
XcfCFBP6989P_RS07380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP6989P_RS07385	COG0575	Belongs to the CDS family
XcfCFBP6989P_RS07390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP6989P_RS07395	COG0233	cytoplasmic translational termination
XcfCFBP6989P_RS07400	COG0528	UMP kinase activity
XcfCFBP6989P_RS07410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP6989P_RS07415	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP6989P_RS07455	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP6989P_RS07465	COG1393	Belongs to the ArsC family
XcfCFBP6989P_RS07470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6989P_RS07475	COG0367	asparagine synthase
XcfCFBP6989P_RS07485	COG4774	siderophore transport
XcfCFBP6989P_RS07570	COG4397	Mu-like prophage major head subunit gpT
XcfCFBP6989P_RS07590	COG2369	cell adhesion
XcfCFBP6989P_RS07595	COG4383	Mu-like prophage protein gp29
XcfCFBP6989P_RS07600	COG4373	Mu-like prophage FluMu protein gp28
XcfCFBP6989P_RS07620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6989P_RS07645	COG5566	PFAM Mor transcription activator
XcfCFBP6989P_RS07710	COG2842	Transposition protein
XcfCFBP6989P_RS07715	COG2801	Transposase and inactivated derivatives
XcfCFBP6989P_RS07755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6989P_RS07785	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6989P_RS07790	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS07840	COG0339	signal peptide processing
XcfCFBP6989P_RS07845	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6989P_RS07900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP6989P_RS07905	COG0084	hydrolase, TatD family'
XcfCFBP6989P_RS07920	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS07940	COG0367	asparagine synthase
XcfCFBP6989P_RS07950	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6989P_RS07955	COG0415	Belongs to the DNA photolyase family
XcfCFBP6989P_RS07965	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS08010	COG3706	GGDEF domain
XcfCFBP6989P_RS08200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP6989P_RS08215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6989P_RS08225	COG0497	DNA recombination
XcfCFBP6989P_RS08230	COG1420	regulation of RNA biosynthetic process
XcfCFBP6989P_RS08235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP6989P_RS08240	COG0443	Heat shock 70 kDa protein
XcfCFBP6989P_RS08245	COG0484	heat shock protein binding
XcfCFBP6989P_RS08250	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP6989P_RS08280	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS08285	COG1132	(ABC) transporter
XcfCFBP6989P_RS08310	COG0567	Dehydrogenase, E1 component
XcfCFBP6989P_RS08320	COG2850	peptidyl-arginine hydroxylation
XcfCFBP6989P_RS08340	COG1253	flavin adenine dinucleotide binding
XcfCFBP6989P_RS08370	COG1131	(ABC) transporter
XcfCFBP6989P_RS08375	COG1725	Transcriptional regulator
XcfCFBP6989P_RS08385	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6989P_RS08400	COG2900	Belongs to the SlyX family
XcfCFBP6989P_RS08425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6989P_RS08435	COG1410	methionine synthase
XcfCFBP6989P_RS08435	COG0646	methionine synthase
XcfCFBP6989P_RS08440	COG0646	methionine synthase
XcfCFBP6989P_RS08440	COG1410	methionine synthase
XcfCFBP6989P_RS08445	COG2226	methyltransferase
XcfCFBP6989P_RS08450	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS08460	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS08485	COG0557	exoribonuclease II activity
XcfCFBP6989P_RS08495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6989P_RS08505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6989P_RS08515	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP6989P_RS08520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP6989P_RS08525	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP6989P_RS08530	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP6989P_RS08535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP6989P_RS08560	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6989P_RS08565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP6989P_RS08575	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS08585	COG0494	nUDIX hydrolase
XcfCFBP6989P_RS08630	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP6989P_RS08630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6989P_RS08635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP6989P_RS08660	COG2925	Exonuclease
XcfCFBP6989P_RS08665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6989P_RS08670	COG3844	kynureninase activity
XcfCFBP6989P_RS08680	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6989P_RS08685	COG0288	reversible hydration of carbon dioxide
XcfCFBP6989P_RS08765	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP6989P_RS08770	COG0316	Belongs to the HesB IscA family
XcfCFBP6989P_RS08775	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP6989P_RS08780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP6989P_RS08785	COG0359	binds to the 23S rRNA
XcfCFBP6989P_RS08800	COG3115	cell septum assembly
XcfCFBP6989P_RS08810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6989P_RS08815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcfCFBP6989P_RS08820	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP6989P_RS08835	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP6989P_RS08845	COG4993	Dehydrogenase
XcfCFBP6989P_RS08855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP6989P_RS08865	COG2986	histidine ammonia-lyase
XcfCFBP6989P_RS08870	COG1228	amidohydrolase
XcfCFBP6989P_RS08905	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP6989P_RS08910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP6989P_RS08915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP6989P_RS08920	COG1605	Chorismate mutase
XcfCFBP6989P_RS08920	COG0077	Prephenate dehydratase
XcfCFBP6989P_RS08925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP6989P_RS08940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP6989P_RS08945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6989P_RS08950	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS08965	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS08990	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP6989P_RS08995	COG0784	Response regulator, receiver
XcfCFBP6989P_RS08995	COG4191	Histidine kinase
XcfCFBP6989P_RS09010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6989P_RS09020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6989P_RS09030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6989P_RS09045	COG1595	DNA-templated transcription, initiation
XcfCFBP6989P_RS09095	COG2244	polysaccharide biosynthetic process
XcfCFBP6989P_RS09125	COG2264	protein methyltransferase activity
XcfCFBP6989P_RS09150	COG1136	(ABC) transporter
XcfCFBP6989P_RS09160	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS09165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6989P_RS09180	COG1253	flavin adenine dinucleotide binding
XcfCFBP6989P_RS09190	COG0306	phosphate transporter
XcfCFBP6989P_RS09215	COG0504	CTP synthase activity
XcfCFBP6989P_RS09230	COG0148	phosphopyruvate hydratase activity
XcfCFBP6989P_RS09235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP6989P_RS09240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP6989P_RS09245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP6989P_RS09250	COG0585	pseudouridine synthase activity
XcfCFBP6989P_RS09255	COG2840	Smr protein MutS2
XcfCFBP6989P_RS09260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP6989P_RS09265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6989P_RS09270	COG1238	metal cluster binding
XcfCFBP6989P_RS09285	COG1534	Rna-binding protein
XcfCFBP6989P_RS09290	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP6989P_RS09300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP6989P_RS09305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP6989P_RS09315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP6989P_RS09320	COG1546	Belongs to the CinA family
XcfCFBP6989P_RS09330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6989P_RS09335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP6989P_RS09340	COG2137	regulation of response to DNA damage stimulus
XcfCFBP6989P_RS09345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP6989P_RS09350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP6989P_RS09370	COG1741	Belongs to the pirin family
XcfCFBP6989P_RS09375	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS09400	COG0351	phosphomethylpyrimidine kinase
XcfCFBP6989P_RS09415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP6989P_RS09420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP6989P_RS09435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6989P_RS09445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP6989P_RS09450	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP6989P_RS09460	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6989P_RS09465	COG0800	Aldolase
XcfCFBP6989P_RS09500	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP6989P_RS09510	COG1070	Carbohydrate kinase
XcfCFBP6989P_RS09515	COG2115	Belongs to the xylose isomerase family
XcfCFBP6989P_RS09520	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS09535	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6989P_RS09540	COG1469	GTP cyclohydrolase I activity
XcfCFBP6989P_RS09560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP6989P_RS09565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP6989P_RS09570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP6989P_RS09595	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6989P_RS09605	COG2203	Gaf domain
XcfCFBP6989P_RS09605	COG4251	negative regulation of phosphorylation
XcfCFBP6989P_RS09605	COG5001	Diguanylate cyclase
XcfCFBP6989P_RS09605	COG3706	GGDEF domain
XcfCFBP6989P_RS09610	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6989P_RS09615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP6989P_RS09625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP6989P_RS09630	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6989P_RS09645	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP6989P_RS09650	COG0697	spore germination
XcfCFBP6989P_RS09655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP6989P_RS09660	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP6989P_RS09680	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6989P_RS09720	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS09725	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP6989P_RS09725	COG0726	polysaccharide deacetylase
XcfCFBP6989P_RS09760	COG3328	transposase activity
XcfCFBP6989P_RS09790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XcfCFBP6989P_RS09800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6989P_RS09805	COG0124	histidyl-tRNA synthetase
XcfCFBP6989P_RS09815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP6989P_RS09820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP6989P_RS09825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6989P_RS09830	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP6989P_RS09830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP6989P_RS09835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP6989P_RS09840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP6989P_RS09845	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP6989P_RS09850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP6989P_RS09850	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP6989P_RS09865	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP6989P_RS09870	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP6989P_RS09875	COG0235	Class ii aldolase
XcfCFBP6989P_RS09880	COG0531	amino acid
XcfCFBP6989P_RS09885	COG0531	amino acid
XcfCFBP6989P_RS09895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP6989P_RS09900	COG0277	FAD linked oxidase domain protein
XcfCFBP6989P_RS09920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6989P_RS09965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6989P_RS09975	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP6989P_RS09980	COG0505	Belongs to the CarA family
XcfCFBP6989P_RS09990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP6989P_RS09995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6989P_RS10005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP6989P_RS10015	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6989P_RS10025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP6989P_RS10035	COG0784	Response regulator, receiver
XcfCFBP6989P_RS10035	COG2198	Histidine kinase
XcfCFBP6989P_RS10035	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS10040	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS10040	COG2198	Histidine kinase
XcfCFBP6989P_RS10040	COG0784	Response regulator, receiver
XcfCFBP6989P_RS10045	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS10050	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6989P_RS10080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6989P_RS10090	COG2201	protein-glutamate methylesterase activity
XcfCFBP6989P_RS10095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP6989P_RS10105	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10120	COG0835	chemotaxis
XcfCFBP6989P_RS10140	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10145	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10155	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10165	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10170	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10175	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10180	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10190	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS10215	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS10225	COG0835	chemotaxis
XcfCFBP6989P_RS10235	COG1360	Flagellar Motor Protein
XcfCFBP6989P_RS10240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP6989P_RS10255	COG1192	Involved in chromosome partitioning
XcfCFBP6989P_RS10320	COG0784	Response regulator, receiver
XcfCFBP6989P_RS10320	COG0643	Histidine kinase
XcfCFBP6989P_RS10320	COG2198	Histidine kinase
XcfCFBP6989P_RS10375	COG1684	flagellar biosynthetic protein fliR
XcfCFBP6989P_RS10390	COG3190	flagellar
XcfCFBP6989P_RS10440	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP6989P_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS10485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6989P_RS10505	COG2201	protein-glutamate methylesterase activity
XcfCFBP6989P_RS10535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcfCFBP6989P_RS10550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcfCFBP6989P_RS10560	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6989P_RS10560	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6989P_RS10565	COG1706	bacterial-type flagellum-dependent cell motility
XcfCFBP6989P_RS10570	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcfCFBP6989P_RS10580	COG4787	bacterial-type flagellum-dependent cell motility
XcfCFBP6989P_RS10590	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcfCFBP6989P_RS10595	COG1558	bacterial-type flagellum-dependent cell motility
XcfCFBP6989P_RS10605	COG0784	Response regulator, receiver
XcfCFBP6989P_RS10605	COG0835	chemotaxis
XcfCFBP6989P_RS10630	COG5002	protein histidine kinase activity
XcfCFBP6989P_RS10660	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP6989P_RS10665	COG0482	sulfurtransferase activity
XcfCFBP6989P_RS10680	COG0542	response to heat
XcfCFBP6989P_RS10690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP6989P_RS10700	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6989P_RS10705	COG1674	ftsk spoiiie
XcfCFBP6989P_RS10715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP6989P_RS10725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP6989P_RS10730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP6989P_RS10735	COG0183	Belongs to the thiolase family
XcfCFBP6989P_RS10740	COG1024	Enoyl-CoA hydratase
XcfCFBP6989P_RS10740	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6989P_RS10755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP6989P_RS10765	COG1426	Protein conserved in bacteria
XcfCFBP6989P_RS10775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6989P_RS10780	COG1160	GTP binding
XcfCFBP6989P_RS10785	COG0303	'Molybdopterin
XcfCFBP6989P_RS10790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP6989P_RS10825	COG0708	Exodeoxyribonuclease III
XcfCFBP6989P_RS10835	COG0303	'Molybdopterin
XcfCFBP6989P_RS10840	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP6989P_RS10870	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP6989P_RS10885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcfCFBP6989P_RS10890	COG0668	transmembrane transport
XcfCFBP6989P_RS10900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP6989P_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS10920	COG1183	phosphatidylcholine synthase activity
XcfCFBP6989P_RS10930	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP6989P_RS10945	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6989P_RS10945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6989P_RS10955	COG2183	response to ionizing radiation
XcfCFBP6989P_RS10960	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS10960	COG0784	Response regulator, receiver
XcfCFBP6989P_RS11020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS11025	COG0800	Aldolase
XcfCFBP6989P_RS11030	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6989P_RS11035	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP6989P_RS11040	COG0837	glucose binding
XcfCFBP6989P_RS11045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6989P_RS11055	COG0354	folic acid binding
XcfCFBP6989P_RS11070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP6989P_RS11085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP6989P_RS11090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP6989P_RS11100	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP6989P_RS11105	COG1136	(ABC) transporter
XcfCFBP6989P_RS11120	COG0811	peptide transport
XcfCFBP6989P_RS11125	COG0848	biopolymer transport protein
XcfCFBP6989P_RS11130	COG1132	(ABC) transporter
XcfCFBP6989P_RS11135	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP6989P_RS11140	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP6989P_RS11145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP6989P_RS11155	COG0322	excinuclease ABC activity
XcfCFBP6989P_RS11160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6989P_RS11185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP6989P_RS11205	COG1054	Belongs to the UPF0176 family
XcfCFBP6989P_RS11215	COG1530	ribonuclease E activity
XcfCFBP6989P_RS11225	COG3064	Membrane
XcfCFBP6989P_RS11230	COG0428	transporter
XcfCFBP6989P_RS11240	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP6989P_RS11245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP6989P_RS11245	COG0316	Belongs to the HesB IscA family
XcfCFBP6989P_RS11290	COG1073	alpha beta
XcfCFBP6989P_RS11290	COG2226	methyltransferase
XcfCFBP6989P_RS11295	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6989P_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS11315	COG5599	Phosphatase
XcfCFBP6989P_RS11345	COG2951	lytic endotransglycosylase activity
XcfCFBP6989P_RS11370	COG3220	belongs to the UPF0276 family
XcfCFBP6989P_RS11390	COG3920	Histidine kinase
XcfCFBP6989P_RS11400	COG1238	metal cluster binding
XcfCFBP6989P_RS11430	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6989P_RS11470	COG4566	intracellular signal transduction
XcfCFBP6989P_RS11480	COG5001	Diguanylate cyclase
XcfCFBP6989P_RS11500	COG3685	Protein conserved in bacteria
XcfCFBP6989P_RS11515	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6989P_RS11515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6989P_RS11530	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS11545	COG1335	isochorismatase
XcfCFBP6989P_RS11565	COG2197	response regulator
XcfCFBP6989P_RS11580	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS11585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6989P_RS11590	COG3002	Belongs to the UPF0753 family
XcfCFBP6989P_RS11595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6989P_RS11595	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6989P_RS11605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP6989P_RS11615	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6989P_RS11615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6989P_RS11620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP6989P_RS11630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6989P_RS11635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP6989P_RS11645	COG0776	regulation of translation
XcfCFBP6989P_RS11650	COG0539	negative regulation of cytoplasmic translation
XcfCFBP6989P_RS11655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP6989P_RS11670	COG2957	Belongs to the agmatine deiminase family
XcfCFBP6989P_RS11675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6989P_RS11700	COG0395	ABC-type sugar transport system, permease component
XcfCFBP6989P_RS11705	COG1175	transmembrane transport
XcfCFBP6989P_RS11735	COG2350	Protein conserved in bacteria
XcfCFBP6989P_RS11740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP6989P_RS11745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP6989P_RS11750	COG1187	pseudouridine synthase activity
XcfCFBP6989P_RS11770	COG0436	Aminotransferase
XcfCFBP6989P_RS11775	COG4133	protoheme IX ABC transporter activity
XcfCFBP6989P_RS11795	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6989P_RS11800	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP6989P_RS11820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6989P_RS11825	COG1278	Cold shock
XcfCFBP6989P_RS11830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP6989P_RS11835	COG4988	ABC transporter
XcfCFBP6989P_RS11845	COG1294	oxidase, subunit
XcfCFBP6989P_RS11875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP6989P_RS11880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP6989P_RS11890	COG0165	Argininosuccinate lyase
XcfCFBP6989P_RS11895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP6989P_RS11905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP6989P_RS11910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6989P_RS11920	COG0137	argininosuccinate synthase activity
XcfCFBP6989P_RS11925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP6989P_RS11935	COG0215	cysteine-tRNA ligase activity
XcfCFBP6989P_RS11940	COG2166	iron-sulfur cluster assembly
XcfCFBP6989P_RS11955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP6989P_RS11960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP6989P_RS11980	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP6989P_RS12030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP6989P_RS12035	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6989P_RS12045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6989P_RS12055	COG3300	MHYT domain
XcfCFBP6989P_RS12055	COG5001	Diguanylate cyclase
XcfCFBP6989P_RS12070	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP6989P_RS12075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP6989P_RS12090	COG0488	(ABC) transporter
XcfCFBP6989P_RS12095	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6989P_RS12100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP6989P_RS12105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP6989P_RS12115	COG0625	glutathione transferase activity
XcfCFBP6989P_RS12125	COG4681	YaeQ
XcfCFBP6989P_RS12130	COG2081	HI0933 family
XcfCFBP6989P_RS12140	COG0501	Belongs to the peptidase M48B family
XcfCFBP6989P_RS12145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6989P_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS12175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP6989P_RS12180	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6989P_RS12185	COG0802	atpase or kinase
XcfCFBP6989P_RS12190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP6989P_RS12190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6989P_RS12195	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6989P_RS12200	COG1570	exodeoxyribonuclease VII activity
XcfCFBP6989P_RS12210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6989P_RS12245	COG0582	viral genome integration into host DNA
XcfCFBP6989P_RS12435	COG3328	transposase activity
XcfCFBP6989P_RS12455	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6989P_RS12545	COG3723	Recombinational DNA repair protein, rece pathway
XcfCFBP6989P_RS12585	COG0835	chemotaxis
XcfCFBP6989P_RS12590	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS12595	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP6989P_RS12600	COG1201	RNA secondary structure unwinding
XcfCFBP6989P_RS12620	COG2969	positive regulation of protein catabolic process
XcfCFBP6989P_RS12625	COG0625	glutathione transferase activity
XcfCFBP6989P_RS12630	COG2857	Cytochrome c1
XcfCFBP6989P_RS12635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP6989P_RS12640	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6989P_RS12645	COG0741	lytic transglycosylase activity
XcfCFBP6989P_RS12660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6989P_RS12665	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP6989P_RS12675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP6989P_RS12685	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP6989P_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6989P_RS12705	COG1177	transmembrane transport
XcfCFBP6989P_RS12710	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP6989P_RS12720	COG3842	ATPase activity
XcfCFBP6989P_RS12740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP6989P_RS12760	COG0174	glutamine synthetase
XcfCFBP6989P_RS12765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6989P_RS12775	COG2703	oxygen carrier activity
XcfCFBP6989P_RS12780	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS12790	COG0243	molybdopterin cofactor binding
XcfCFBP6989P_RS12795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP6989P_RS12800	COG2223	nitrite transmembrane transporter activity
XcfCFBP6989P_RS12805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP6989P_RS12815	COG2733	membrane
XcfCFBP6989P_RS12820	COG5002	protein histidine kinase activity
XcfCFBP6989P_RS12820	COG0784	Response regulator, receiver
XcfCFBP6989P_RS12820	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS12835	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS12840	COG2902	Dehydrogenase
XcfCFBP6989P_RS12850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS12855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS12860	COG1609	Transcriptional regulator
XcfCFBP6989P_RS12865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6989P_RS12865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6989P_RS12870	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP6989P_RS12875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6989P_RS12875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6989P_RS12905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP6989P_RS12915	COG1862	Preprotein translocase
XcfCFBP6989P_RS12920	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP6989P_RS12925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP6989P_RS12960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP6989P_RS12965	COG3291	Pkd domain containing protein
XcfCFBP6989P_RS12970	COG0405	Gamma-glutamyltransferase
XcfCFBP6989P_RS12975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP6989P_RS12985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP6989P_RS12990	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP6989P_RS12995	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6989P_RS13100	COG0531	amino acid
XcfCFBP6989P_RS13115	COG0006	proline dipeptidase activity
XcfCFBP6989P_RS13125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6989P_RS13140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6989P_RS13145	COG3938	Belongs to the proline racemase family
XcfCFBP6989P_RS13155	COG0552	protein localization to endoplasmic reticulum
XcfCFBP6989P_RS13160	COG1194	a g-specific adenine glycosylase
XcfCFBP6989P_RS13165	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP6989P_RS13170	COG0784	Response regulator, receiver
XcfCFBP6989P_RS13170	COG4191	Histidine kinase
XcfCFBP6989P_RS13185	COG0322	excinuclease ABC activity
XcfCFBP6989P_RS13200	COG3040	lipid binding
XcfCFBP6989P_RS13210	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS13220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP6989P_RS13240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6989P_RS13245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6989P_RS13250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6989P_RS13275	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS13285	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS13290	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS13340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6989P_RS13340	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP6989P_RS13345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP6989P_RS13360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP6989P_RS13365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP6989P_RS13380	COG2190	(PTS) system
XcfCFBP6989P_RS13380	COG2211	Major facilitator Superfamily
XcfCFBP6989P_RS13390	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6989P_RS13405	COG0366	Alpha amylase catalytic
XcfCFBP6989P_RS13440	COG3702	type iv secretory pathway
XcfCFBP6989P_RS13460	COG2948	multi-organism process
XcfCFBP6989P_RS13480	COG3505	Type IV secretory pathway VirD4
XcfCFBP6989P_RS13490	COG0582	viral genome integration into host DNA
XcfCFBP6989P_RS13500	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XcfCFBP6989P_RS13620	COG0556	nucleotide-excision repair
XcfCFBP6989P_RS13625	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6989P_RS13660	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6989P_RS13665	COG1611	Belongs to the LOG family
XcfCFBP6989P_RS13675	COG2095	MarC family integral membrane protein
XcfCFBP6989P_RS13685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6989P_RS13720	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP6989P_RS13725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP6989P_RS13730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP6989P_RS13735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP6989P_RS13740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP6989P_RS13745	COG0195	Participates in both transcription termination and antitermination
XcfCFBP6989P_RS13750	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP6989P_RS13760	COG1007	ATP synthesis coupled electron transport
XcfCFBP6989P_RS13785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6989P_RS13790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP6989P_RS13800	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP6989P_RS13805	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP6989P_RS13810	COG0649	NAD binding
XcfCFBP6989P_RS13815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6989P_RS13820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6989P_RS13825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6989P_RS13840	COG0149	triose-phosphate isomerase activity
XcfCFBP6989P_RS13845	COG0300	oxidoreductase activity
XcfCFBP6989P_RS13875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6989P_RS13880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP6989P_RS13885	COG0159	tryptophan synthase activity
XcfCFBP6989P_RS13895	COG0133	tryptophan synthase activity
XcfCFBP6989P_RS13905	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP6989P_RS13910	COG0101	tRNA pseudouridine synthase activity
XcfCFBP6989P_RS13925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP6989P_RS13930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP6989P_RS13935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP6989P_RS13940	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6989P_RS13950	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP6989P_RS13960	COG0433	COG0433 Predicted ATPase
XcfCFBP6989P_RS13965	COG0494	nUDIX hydrolase
XcfCFBP6989P_RS13980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6989P_RS13985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6989P_RS14010	COG0717	Belongs to the dCTP deaminase family
XcfCFBP6989P_RS14015	COG0489	protein tyrosine kinase activity
XcfCFBP6989P_RS14035	COG3590	peptidase
XcfCFBP6989P_RS14040	COG3590	peptidase
XcfCFBP6989P_RS14060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6989P_RS14065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6989P_RS14070	COG2311	Membrane
XcfCFBP6989P_RS14075	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6989P_RS14080	COG0791	NLP P60 protein
XcfCFBP6989P_RS14085	COG0791	NLP P60 protein
XcfCFBP6989P_RS14095	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6989P_RS14100	COG1301	dicarboxylic acid transport
XcfCFBP6989P_RS14105	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP6989P_RS14110	COG0037	tRNA processing
XcfCFBP6989P_RS14115	COG1722	exodeoxyribonuclease VII activity
XcfCFBP6989P_RS14120	COG0142	geranyltranstransferase activity
XcfCFBP6989P_RS14125	COG4104	PAAR repeat-containing protein
XcfCFBP6989P_RS14135	COG0312	modulator of DNA gyrase
XcfCFBP6989P_RS14140	COG3028	Belongs to the UPF0307 family
XcfCFBP6989P_RS14145	COG0312	modulator of DNA gyrase
XcfCFBP6989P_RS14155	COG3164	Protein of unknown function
XcfCFBP6989P_RS14165	COG0424	maF-like protein
XcfCFBP6989P_RS14170	COG2968	Membrane
XcfCFBP6989P_RS14185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP6989P_RS14200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP6989P_RS14215	COG0495	leucyl-tRNA aminoacylation
XcfCFBP6989P_RS14225	COG3118	belongs to the thioredoxin family
XcfCFBP6989P_RS14265	COG2155	Conserved Protein
XcfCFBP6989P_RS14310	COG1132	(ABC) transporter
XcfCFBP6989P_RS14335	COG1538	Outer membrane efflux protein
XcfCFBP6989P_RS14340	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS14345	COG5000	phosphorelay sensor kinase activity
XcfCFBP6989P_RS14345	COG5002	protein histidine kinase activity
XcfCFBP6989P_RS14350	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6989P_RS14360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6989P_RS14380	COG1187	pseudouridine synthase activity
XcfCFBP6989P_RS14385	COG5001	Diguanylate cyclase
XcfCFBP6989P_RS14385	COG5002	protein histidine kinase activity
XcfCFBP6989P_RS14395	COG1595	DNA-templated transcription, initiation
XcfCFBP6989P_RS14495	COG2951	lytic endotransglycosylase activity
XcfCFBP6989P_RS14545	COG0667	Aldo Keto reductase
XcfCFBP6989P_RS14550	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS14555	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS14565	COG2207	Transcriptional regulator
XcfCFBP6989P_RS14575	COG1309	transcriptional regulator
XcfCFBP6989P_RS14585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS14600	COG0735	belongs to the Fur family
XcfCFBP6989P_RS14605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6989P_RS14630	COG4452	Inner membrane protein CreD
XcfCFBP6989P_RS14640	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS14645	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS14650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP6989P_RS14660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP6989P_RS14670	COG0643	Histidine kinase
XcfCFBP6989P_RS14670	COG2198	Histidine kinase
XcfCFBP6989P_RS14675	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS14680	COG0835	chemotaxis
XcfCFBP6989P_RS14685	COG2199	diguanylate cyclase activity
XcfCFBP6989P_RS14685	COG2200	EAL domain
XcfCFBP6989P_RS14685	COG2202	Pas domain
XcfCFBP6989P_RS14690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6989P_RS14700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6989P_RS14705	COG3590	peptidase
XcfCFBP6989P_RS14715	COG0588	phosphoglycerate mutase activity
XcfCFBP6989P_RS14720	COG1515	deoxyribonuclease V activity
XcfCFBP6989P_RS14730	COG1741	Belongs to the pirin family
XcfCFBP6989P_RS14745	COG1741	Belongs to the pirin family
XcfCFBP6989P_RS14750	COG1966	Carbon starvation protein
XcfCFBP6989P_RS14755	COG2879	small protein
XcfCFBP6989P_RS14790	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP6989P_RS14795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6989P_RS14800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6989P_RS14805	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6989P_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS14810	COG3321	synthase
XcfCFBP6989P_RS14810	COG0604	alcohol dehydrogenase
XcfCFBP6989P_RS14820	COG0629	single-stranded DNA binding
XcfCFBP6989P_RS14825	COG0142	geranyltranstransferase activity
XcfCFBP6989P_RS14840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP6989P_RS14855	COG0527	aspartate kinase activity
XcfCFBP6989P_RS14860	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6989P_RS14865	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6989P_RS14875	COG1764	response to oxidative stress
XcfCFBP6989P_RS14880	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6989P_RS14885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6989P_RS14890	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6989P_RS14895	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6989P_RS14920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP6989P_RS14935	COG0739	heme binding
XcfCFBP6989P_RS14955	COG0693	protein deglycase activity
XcfCFBP6989P_RS14965	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP6989P_RS14970	COG0719	Fe-S assembly protein
XcfCFBP6989P_RS14975	COG0396	ATPase activity
XcfCFBP6989P_RS14980	COG0719	Fe-S assembly protein
XcfCFBP6989P_RS14985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP6989P_RS14995	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP6989P_RS15005	COG3128	pkhd-type hydroxylase
XcfCFBP6989P_RS15030	COG1477	protein flavinylation
XcfCFBP6989P_RS15035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6989P_RS15045	COG1555	photosystem II stabilization
XcfCFBP6989P_RS15060	COG3178	'Phosphotransferase
XcfCFBP6989P_RS15065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP6989P_RS15075	COG0628	permease
XcfCFBP6989P_RS15085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP6989P_RS15095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP6989P_RS15115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP6989P_RS15120	COG0271	Belongs to the BolA IbaG family
XcfCFBP6989P_RS15130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP6989P_RS15140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP6989P_RS15145	COG1137	ATPase activity
XcfCFBP6989P_RS15160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6989P_RS15165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP6989P_RS15170	COG1660	Displays ATPase and GTPase activities
XcfCFBP6989P_RS15180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6989P_RS15185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6989P_RS15190	COG2239	Acts as a magnesium transporter
XcfCFBP6989P_RS15200	COG1294	oxidase, subunit
XcfCFBP6989P_RS15205	COG1271	oxidase subunit
XcfCFBP6989P_RS15215	COG1113	amino acid transport
XcfCFBP6989P_RS15235	COG2197	response regulator
XcfCFBP6989P_RS15240	COG0531	amino acid
XcfCFBP6989P_RS15310	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS15320	COG0754	glutathionylspermidine amidase activity
XcfCFBP6989P_RS15345	COG1842	Phage shock protein A
XcfCFBP6989P_RS15355	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP6989P_RS15360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP6989P_RS15365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP6989P_RS15375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP6989P_RS15380	COG2814	Major facilitator Superfamily
XcfCFBP6989P_RS15400	COG2198	Histidine kinase
XcfCFBP6989P_RS15400	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS15400	COG0784	Response regulator, receiver
XcfCFBP6989P_RS15405	COG2353	YceI-like domain
XcfCFBP6989P_RS15425	COG1760	l-serine dehydratase
XcfCFBP6989P_RS15435	COG0460	homoserine dehydrogenase
XcfCFBP6989P_RS15435	COG0527	aspartate kinase activity
XcfCFBP6989P_RS15440	COG0626	cystathionine gamma-synthase activity
XcfCFBP6989P_RS15445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6989P_RS15450	COG0739	heme binding
XcfCFBP6989P_RS15455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP6989P_RS15460	COG1272	protein, Hemolysin III
XcfCFBP6989P_RS15465	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP6989P_RS15470	COG0516	GMP reductase activity
XcfCFBP6989P_RS15470	COG0517	IMP dehydrogenase activity
XcfCFBP6989P_RS15475	COG0463	Glycosyl transferase, family 2
XcfCFBP6989P_RS15480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6989P_RS15485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP6989P_RS15495	COG4771	TonB-dependent receptor
XcfCFBP6989P_RS15505	COG1309	transcriptional regulator
XcfCFBP6989P_RS15515	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6989P_RS15545	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP6989P_RS15550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP6989P_RS15570	COG1742	UPF0060 membrane protein
XcfCFBP6989P_RS15575	COG3956	TIGRFAM MazG family protein
XcfCFBP6989P_RS15580	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP6989P_RS15585	COG0494	nUDIX hydrolase
XcfCFBP6989P_RS15595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP6989P_RS15600	COG0837	glucose binding
XcfCFBP6989P_RS15615	COG3858	chitin binding
XcfCFBP6989P_RS15615	COG1388	LysM domain
XcfCFBP6989P_RS15620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6989P_RS15630	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6989P_RS15645	COG0531	amino acid
XcfCFBP6989P_RS15655	COG1486	melibiose metabolic process
XcfCFBP6989P_RS15665	COG3537	Alpha-1,2-mannosidase
XcfCFBP6989P_RS15700	COG3142	Participates in the control of copper homeostasis
XcfCFBP6989P_RS15705	COG1446	asparaginase
XcfCFBP6989P_RS15725	COG2198	Histidine kinase
XcfCFBP6989P_RS15725	COG0784	Response regulator, receiver
XcfCFBP6989P_RS15725	COG0643	Histidine kinase
XcfCFBP6989P_RS15730	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS15735	COG0835	chemotaxis
XcfCFBP6989P_RS15750	COG0189	ligase activity
XcfCFBP6989P_RS15760	COG1397	ADP-ribosylglycohydrolase
XcfCFBP6989P_RS15770	COG1199	ATP-dependent helicase activity
XcfCFBP6989P_RS15780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6989P_RS15785	COG1216	Glycosyl transferase, family 2
XcfCFBP6989P_RS15785	COG1442	glycosyl transferase family 8
XcfCFBP6989P_RS15795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6989P_RS15805	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP6989P_RS15810	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP6989P_RS15815	COG0535	radical SAM domain protein
XcfCFBP6989P_RS15820	COG0535	radical SAM domain protein
XcfCFBP6989P_RS15835	COG0837	glucose binding
XcfCFBP6989P_RS15850	COG1643	Atp-dependent helicase
XcfCFBP6989P_RS15855	COG0783	Belongs to the Dps family
XcfCFBP6989P_RS15860	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP6989P_RS15900	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS15920	COG3920	Histidine kinase
XcfCFBP6989P_RS15925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP6989P_RS15935	COG0602	queuosine metabolic process
XcfCFBP6989P_RS15945	COG2885	chlorophyll binding
XcfCFBP6989P_RS15950	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6989P_RS15960	COG0848	biopolymer transport protein
XcfCFBP6989P_RS15970	COG0824	Thioesterase
XcfCFBP6989P_RS15975	COG2255	four-way junction helicase activity
XcfCFBP6989P_RS15980	COG3158	transport of potassium into the cell
XcfCFBP6989P_RS15985	COG0632	four-way junction helicase activity
XcfCFBP6989P_RS15990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP6989P_RS15995	COG0217	transcriptional regulatory protein
XcfCFBP6989P_RS16010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP6989P_RS16025	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS16065	COG0488	(ABC) transporter
XcfCFBP6989P_RS16095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6989P_RS16095	COG4651	solute:proton antiporter activity
XcfCFBP6989P_RS16105	COG4772	TonB-dependent receptor
XcfCFBP6989P_RS16115	COG4264	IucA IucC family
XcfCFBP6989P_RS16130	COG0019	diaminopimelate decarboxylase activity
XcfCFBP6989P_RS16160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP6989P_RS16170	COG1492	cobalamin metabolic process
XcfCFBP6989P_RS16180	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6989P_RS16205	COG4206	TonB-dependent receptor
XcfCFBP6989P_RS16210	COG0542	response to heat
XcfCFBP6989P_RS16215	COG1116	anion transmembrane transporter activity
XcfCFBP6989P_RS16220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6989P_RS16225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP6989P_RS16230	COG0667	Aldo Keto reductase
XcfCFBP6989P_RS16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6989P_RS16240	COG4771	TonB-dependent receptor
XcfCFBP6989P_RS16245	COG2827	Endonuclease containing a URI domain
XcfCFBP6989P_RS16285	COG1877	trehalose-phosphatase activity
XcfCFBP6989P_RS16290	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6989P_RS16305	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS16310	COG3011	Protein conserved in bacteria
XcfCFBP6989P_RS16325	COG0564	pseudouridine synthase activity
XcfCFBP6989P_RS16330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6989P_RS16340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP6989P_RS16340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6989P_RS16350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP6989P_RS16355	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6989P_RS16375	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6989P_RS16390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP6989P_RS16395	COG0237	dephospho-CoA kinase activity
XcfCFBP6989P_RS16420	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6989P_RS16430	COG0189	ligase activity
XcfCFBP6989P_RS16475	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP6989P_RS16480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP6989P_RS16485	COG3273	potassium ion transport
XcfCFBP6989P_RS16485	COG0471	metal ion transport
XcfCFBP6989P_RS16505	COG1970	mechanosensitive ion channel activity
XcfCFBP6989P_RS16515	COG1609	Transcriptional regulator
XcfCFBP6989P_RS16525	COG3250	beta-galactosidase activity
XcfCFBP6989P_RS16530	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6989P_RS16540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6989P_RS16550	COG0308	aminopeptidase N
XcfCFBP6989P_RS16555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS16565	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP6989P_RS16565	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP6989P_RS16570	COG0175	sulfate reduction
XcfCFBP6989P_RS16575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6989P_RS16580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP6989P_RS16585	COG0175	sulfate reduction
XcfCFBP6989P_RS16605	COG0784	Response regulator, receiver
XcfCFBP6989P_RS16605	COG2198	Histidine kinase
XcfCFBP6989P_RS16605	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS16620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6989P_RS16620	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6989P_RS16635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP6989P_RS16640	COG3588	fructose-bisphosphate aldolase
XcfCFBP6989P_RS16645	COG0469	pyruvate kinase activity
XcfCFBP6989P_RS16655	COG0126	phosphoglycerate kinase activity
XcfCFBP6989P_RS16675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP6989P_RS16685	COG3047	cAMP biosynthetic process
XcfCFBP6989P_RS16690	COG3047	cAMP biosynthetic process
XcfCFBP6989P_RS16700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6989P_RS16700	COG3453	Protein conserved in bacteria
XcfCFBP6989P_RS16705	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP6989P_RS16710	COG4149	molybdate abc transporter
XcfCFBP6989P_RS16715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP6989P_RS16750	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP6989P_RS16755	COG0739	heme binding
XcfCFBP6989P_RS16760	COG4773	Receptor
XcfCFBP6989P_RS16765	COG0596	Alpha beta hydrolase
XcfCFBP6989P_RS16770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP6989P_RS16775	COG1301	dicarboxylic acid transport
XcfCFBP6989P_RS16785	COG2304	oxidoreductase activity
XcfCFBP6989P_RS16805	COG0714	Associated with various cellular activities
XcfCFBP6989P_RS16835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP6989P_RS16860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP6989P_RS16870	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP6989P_RS16885	COG2271	Major facilitator Superfamily
XcfCFBP6989P_RS16900	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS16905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6989P_RS16920	COG1561	YicC-like family, N-terminal region
XcfCFBP6989P_RS16925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP6989P_RS16935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP6989P_RS16940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP6989P_RS16955	COG0006	proline dipeptidase activity
XcfCFBP6989P_RS16965	COG0006	proline dipeptidase activity
XcfCFBP6989P_RS16970	COG3079	Belongs to the UPF0149 family
XcfCFBP6989P_RS16990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP6989P_RS17000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP6989P_RS17010	COG2912	Transglutaminase-like superfamily
XcfCFBP6989P_RS17015	COG1773	rubredoxin
XcfCFBP6989P_RS17020	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP6989P_RS17035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6989P_RS17050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6989P_RS17080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP6989P_RS17085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6989P_RS17090	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS17100	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6989P_RS17115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6989P_RS17120	COG0563	adenylate kinase activity
XcfCFBP6989P_RS17135	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP6989P_RS17145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP6989P_RS17165	COG3710	Transcriptional regulator
XcfCFBP6989P_RS17170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP6989P_RS17180	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS17185	COG0405	Gamma-glutamyltransferase
XcfCFBP6989P_RS17190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP6989P_RS17210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP6989P_RS17215	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6989P_RS17220	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP6989P_RS17225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP6989P_RS17245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6989P_RS17250	COG1538	Outer membrane efflux protein
XcfCFBP6989P_RS17255	COG1519	Transferase
XcfCFBP6989P_RS17260	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6989P_RS17315	COG0280	phosphate acetyltransferase
XcfCFBP6989P_RS17315	COG0281	malic enzyme
XcfCFBP6989P_RS17320	COG1301	dicarboxylic acid transport
XcfCFBP6989P_RS17345	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS17350	COG0667	Aldo Keto reductase
XcfCFBP6989P_RS17365	COG2197	response regulator
XcfCFBP6989P_RS17375	COG0642	Histidine kinase
XcfCFBP6989P_RS17390	COG2851	Citrate transporter
XcfCFBP6989P_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS17400	COG1609	Transcriptional regulator
XcfCFBP6989P_RS17405	COG2211	Major facilitator Superfamily
XcfCFBP6989P_RS17435	COG1162	GTPase activity
XcfCFBP6989P_RS17470	COG0436	Aminotransferase
XcfCFBP6989P_RS17485	COG0726	polysaccharide deacetylase
XcfCFBP6989P_RS17490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6989P_RS17505	COG3964	amidohydrolase
XcfCFBP6989P_RS17510	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6989P_RS17530	COG1307	EDD domain protein, DegV family
XcfCFBP6989P_RS17535	COG0242	peptide deformylase activity
XcfCFBP6989P_RS17555	COG0457	Tetratricopeptide repeat
XcfCFBP6989P_RS17560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP6989P_RS17565	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS17570	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS17585	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP6989P_RS17630	COG2188	Transcriptional regulator
XcfCFBP6989P_RS17640	COG1450	Type ii and iii secretion system protein
XcfCFBP6989P_RS17655	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP6989P_RS17660	COG3156	type II secretion system protein K
XcfCFBP6989P_RS17665	COG4795	General secretion pathway protein
XcfCFBP6989P_RS17670	COG2165	general secretion pathway protein
XcfCFBP6989P_RS17675	COG4970	Tfp pilus assembly protein FimT
XcfCFBP6989P_RS17680	COG2165	general secretion pathway protein
XcfCFBP6989P_RS17685	COG1459	type II secretion system
XcfCFBP6989P_RS17690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6989P_RS17695	COG1404	Belongs to the peptidase S8 family
XcfCFBP6989P_RS17700	COG5295	Hep Hag repeat protein
XcfCFBP6989P_RS17705	COG1404	Belongs to the peptidase S8 family
XcfCFBP6989P_RS17710	COG5295	Hep Hag repeat protein
XcfCFBP6989P_RS17720	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP6989P_RS17720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP6989P_RS17725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6989P_RS17730	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6989P_RS17745	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP6989P_RS17755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6989P_RS17770	COG0525	valine-tRNA ligase activity
XcfCFBP6989P_RS17805	COG1183	phosphatidylcholine synthase activity
XcfCFBP6989P_RS17815	COG0442	prolyl-tRNA aminoacylation
XcfCFBP6989P_RS17830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6989P_RS17835	COG1127	ABC transporter
XcfCFBP6989P_RS17840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6989P_RS17840	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP6989P_RS17875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6989P_RS17880	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP6989P_RS17880	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6989P_RS17910	COG2086	electron transfer activity
XcfCFBP6989P_RS17925	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6989P_RS17925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6989P_RS17930	COG0277	FAD linked oxidase domain protein
XcfCFBP6989P_RS17945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6989P_RS17975	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6989P_RS17975	COG1216	Glycosyl transferase, family 2
XcfCFBP6989P_RS17995	COG0626	cystathionine gamma-synthase activity
XcfCFBP6989P_RS18025	COG0625	glutathione transferase activity
XcfCFBP6989P_RS18035	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6989P_RS18045	COG4771	TonB-dependent receptor
XcfCFBP6989P_RS18050	COG0720	synthase
XcfCFBP6989P_RS18075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP6989P_RS18080	COG1956	GAF domain-containing protein
XcfCFBP6989P_RS18090	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP6989P_RS18100	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6989P_RS18105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6989P_RS18110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6989P_RS18125	COG0339	signal peptide processing
XcfCFBP6989P_RS18175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6989P_RS18180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS18185	COG1136	(ABC) transporter
XcfCFBP6989P_RS18190	COG0577	efflux transmembrane transporter activity
XcfCFBP6989P_RS18195	COG1136	(ABC) transporter
XcfCFBP6989P_RS18195	COG0577	efflux transmembrane transporter activity
XcfCFBP6989P_RS18210	COG4191	Histidine kinase
XcfCFBP6989P_RS18215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP6989P_RS18230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP6989P_RS18235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP6989P_RS18240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP6989P_RS18245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP6989P_RS18250	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP6989P_RS18255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP6989P_RS18265	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP6989P_RS18285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6989P_RS18295	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6989P_RS18330	COG2011	ABC-type metal ion transport system permease component
XcfCFBP6989P_RS18335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP6989P_RS18340	COG0697	spore germination
XcfCFBP6989P_RS18345	COG1666	GTP binding
XcfCFBP6989P_RS18355	COG2198	Histidine kinase
XcfCFBP6989P_RS18355	COG5002	protein histidine kinase activity
XcfCFBP6989P_RS18355	COG0784	Response regulator, receiver
XcfCFBP6989P_RS18375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6989P_RS18380	COG1187	pseudouridine synthase activity
XcfCFBP6989P_RS18385	COG2813	Specifically methylates the guanine in position
XcfCFBP6989P_RS18405	COG2202	Pas domain
XcfCFBP6989P_RS18405	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS18425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP6989P_RS18430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6989P_RS18485	COG0842	Transport permease protein
XcfCFBP6989P_RS18495	COG0025	NhaP-type Na H and K H
XcfCFBP6989P_RS18500	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP6989P_RS18505	COG1573	uracil-dna glycosylase
XcfCFBP6989P_RS18515	COG3384	dioxygenase
XcfCFBP6989P_RS18525	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS18535	COG0667	Aldo Keto reductase
XcfCFBP6989P_RS18545	COG3590	peptidase
XcfCFBP6989P_RS18560	COG0531	amino acid
XcfCFBP6989P_RS18575	COG2972	Histidine kinase
XcfCFBP6989P_RS18590	COG3685	Protein conserved in bacteria
XcfCFBP6989P_RS18595	COG3546	catalase activity
XcfCFBP6989P_RS18630	COG2204	response regulator
XcfCFBP6989P_RS18640	COG1271	oxidase subunit
XcfCFBP6989P_RS18645	COG1294	oxidase, subunit
XcfCFBP6989P_RS18660	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS18665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP6989P_RS18685	COG1132	(ABC) transporter
XcfCFBP6989P_RS18700	COG1063	alcohol dehydrogenase
XcfCFBP6989P_RS18775	COG0251	oxidation-reduction process
XcfCFBP6989P_RS18790	COG0840	transmembrane signaling receptor activity
XcfCFBP6989P_RS18805	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS18810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6989P_RS18840	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6989P_RS18855	COG0024	Methionine aminopeptidase
XcfCFBP6989P_RS18870	COG1487	ribonuclease activity
XcfCFBP6989P_RS18945	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6989P_RS19010	COG1196	nuclear chromosome segregation
XcfCFBP6989P_RS19035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6989P_RS19040	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP6989P_RS19045	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6989P_RS19095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6989P_RS19095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP6989P_RS19100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP6989P_RS19105	COG0242	peptide deformylase activity
XcfCFBP6989P_RS19110	COG1652	LysM domain
XcfCFBP6989P_RS19115	COG0758	DNA mediated transformation
XcfCFBP6989P_RS19135	COG1754	DNA topoisomerase type I activity
XcfCFBP6989P_RS19135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6989P_RS19140	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP6989P_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS19165	COG0616	signal peptide processing
XcfCFBP6989P_RS19170	COG0534	Mate efflux family protein
XcfCFBP6989P_RS19190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcfCFBP6989P_RS19195	COG0625	glutathione transferase activity
XcfCFBP6989P_RS19210	COG1252	NADH dehydrogenase
XcfCFBP6989P_RS19215	COG2860	membrane
XcfCFBP6989P_RS19220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6989P_RS19225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP6989P_RS19230	COG2201	protein-glutamate methylesterase activity
XcfCFBP6989P_RS19235	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP6989P_RS19240	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP6989P_RS19245	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6989P_RS19250	COG3118	belongs to the thioredoxin family
XcfCFBP6989P_RS19255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP6989P_RS19260	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcfCFBP6989P_RS19265	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS19285	COG1652	LysM domain
XcfCFBP6989P_RS19290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6989P_RS19290	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6989P_RS19295	COG1473	amidohydrolase
XcfCFBP6989P_RS19300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS19305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6989P_RS19325	COG5383	Protein conserved in bacteria
XcfCFBP6989P_RS19375	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6989P_RS19385	COG0531	amino acid
XcfCFBP6989P_RS19400	COG4682	membrane
XcfCFBP6989P_RS19405	COG2133	pyrroloquinoline quinone binding
XcfCFBP6989P_RS19415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP6989P_RS19420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP6989P_RS19430	COG1610	YqeY-like protein
XcfCFBP6989P_RS19435	COG1295	ribonuclease BN
XcfCFBP6989P_RS19440	COG0358	DNA primase activity
XcfCFBP6989P_RS19455	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP6989P_RS19485	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP6989P_RS19500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP6989P_RS19540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP6989P_RS19545	COG0739	heme binding
XcfCFBP6989P_RS19550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP6989P_RS19560	COG2223	nitrite transmembrane transporter activity
XcfCFBP6989P_RS19565	COG0708	Exodeoxyribonuclease III
XcfCFBP6989P_RS19570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP6989P_RS19580	COG1192	Involved in chromosome partitioning
XcfCFBP6989P_RS19585	COG1475	DNA binding
XcfCFBP6989P_RS19600	COG0463	Glycosyl transferase, family 2
XcfCFBP6989P_RS19620	COG0756	dUTP diphosphatase activity
XcfCFBP6989P_RS19625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP6989P_RS19630	COG2003	Belongs to the UPF0758 family
XcfCFBP6989P_RS19635	COG0018	arginyl-trna synthetase
XcfCFBP6989P_RS19650	COG4221	oxidoreductase activity
XcfCFBP6989P_RS19655	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6989P_RS19655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP6989P_RS19665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6989P_RS19670	COG1166	arginine decarboxylase activity
XcfCFBP6989P_RS19675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP6989P_RS19700	COG3291	Pkd domain containing protein
XcfCFBP6989P_RS19700	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6989P_RS19715	COG0606	chelatase, subunit chli
XcfCFBP6989P_RS19730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP6989P_RS19755	COG1690	Belongs to the RtcB family
XcfCFBP6989P_RS19790	COG1090	epimerase
XcfCFBP6989P_RS19800	COG0642	Histidine kinase
XcfCFBP6989P_RS19820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6989P_RS19850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6989P_RS19855	COG3328	transposase activity
XcfCFBP6989P_RS19865	COG0753	catalase activity
XcfCFBP6989P_RS19880	COG2197	response regulator
XcfCFBP6989P_RS19885	COG4585	Histidine kinase
XcfCFBP6989P_RS19890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS19895	COG1136	(ABC) transporter
XcfCFBP6989P_RS19920	COG0697	spore germination
XcfCFBP6989P_RS19940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6989P_RS19945	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP6989P_RS19950	COG3237	CsbD-like
XcfCFBP6989P_RS19990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP6989P_RS20005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP6989P_RS20050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6989P_RS20070	COG1199	ATP-dependent helicase activity
XcfCFBP6989P_RS20085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP6989P_RS20160	COG0625	glutathione transferase activity
XcfCFBP6989P_RS20195	COG4555	ABC transporter
XcfCFBP6989P_RS20205	COG1476	TRANSCRIPTIONal
XcfCFBP6989P_RS20225	COG1230	cation diffusion facilitator family transporter
XcfCFBP6989P_RS20235	COG4774	siderophore transport
XcfCFBP6989P_RS20250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6989P_RS20255	COG1131	(ABC) transporter
XcfCFBP6989P_RS20260	COG0842	Transport permease protein
XcfCFBP6989P_RS20265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP6989P_RS20285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6989P_RS20295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6989P_RS20300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6989P_RS20310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcfCFBP6989P_RS20310	COG1042	CoA-binding domain protein
XcfCFBP6989P_RS20310	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6989P_RS20315	COG2239	Acts as a magnesium transporter
XcfCFBP6989P_RS20330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6989P_RS20335	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6989P_RS20350	COG3100	YcgL domain-containing protein
XcfCFBP6989P_RS20355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6989P_RS20365	COG0463	Glycosyl transferase, family 2
XcfCFBP6989P_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS20425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6989P_RS20440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6989P_RS20465	COG1506	peptidase
XcfCFBP6989P_RS20465	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6989P_RS20465	COG4946	Tricorn protease homolog
XcfCFBP6989P_RS20480	COG0408	coproporphyrinogen oxidase activity
XcfCFBP6989P_RS20515	COG0515	serine threonine protein kinase
XcfCFBP6989P_RS20520	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6989P_RS20690	COG0210	DNA helicase
XcfCFBP6989P_RS20700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6989P_RS20705	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS20710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6989P_RS20720	COG2159	amidohydrolase
XcfCFBP6989P_RS20740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6989P_RS20760	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP6989P_RS20765	COG3540	Alkaline phosphatase
XcfCFBP6989P_RS20775	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP6989P_RS20790	COG0708	Exodeoxyribonuclease III
XcfCFBP6989P_RS20795	COG1940	carbohydrate kinase activity
XcfCFBP6989P_RS20795	COG1846	Transcriptional regulator
XcfCFBP6989P_RS20805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6989P_RS20815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP6989P_RS20820	COG3162	membrane
XcfCFBP6989P_RS20830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP6989P_RS20855	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6989P_RS20875	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS20880	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP6989P_RS20885	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6989P_RS20890	COG3254	rhamnose metabolic process
XcfCFBP6989P_RS20895	COG0738	Major facilitator superfamily
XcfCFBP6989P_RS20900	COG1414	Transcriptional regulator
XcfCFBP6989P_RS20905	COG1971	Probably functions as a manganese efflux pump
XcfCFBP6989P_RS20910	COG2205	protein histidine kinase activity
XcfCFBP6989P_RS20920	COG3459	Glycosyltransferase 36 associated
XcfCFBP6989P_RS20925	COG2211	Major facilitator Superfamily
XcfCFBP6989P_RS20930	COG3265	gluconokinase activity
XcfCFBP6989P_RS20935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6989P_RS20955	COG2911	Protein conserved in bacteria
XcfCFBP6989P_RS20960	COG0729	surface antigen
XcfCFBP6989P_RS21000	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP6989P_RS21005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6989P_RS21020	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6989P_RS21020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6989P_RS21030	COG0805	protein transport
XcfCFBP6989P_RS21035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6989P_RS21040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6989P_RS21050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP6989P_RS21065	COG2974	May be involved in recombination
XcfCFBP6989P_RS21070	COG0037	tRNA processing
XcfCFBP6989P_RS21075	COG2115	Belongs to the xylose isomerase family
XcfCFBP6989P_RS21085	COG3661	Belongs to the glycosyl hydrolase 67 family
XcfCFBP6989P_RS21095	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6989P_RS21105	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6989P_RS21110	COG0246	Mannitol dehydrogenase
XcfCFBP6989P_RS21155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6989P_RS21180	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6989P_RS21190	COG3250	beta-galactosidase activity
XcfCFBP6989P_RS21195	COG1904	glucuronate isomerase
XcfCFBP6989P_RS21215	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6989P_RS21230	COG2211	Major facilitator Superfamily
XcfCFBP6989P_RS21285	COG0604	alcohol dehydrogenase
XcfCFBP6989P_RS21285	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS21285	COG3321	synthase
XcfCFBP6989P_RS21290	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP6989P_RS21320	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP6989P_RS21325	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP6989P_RS21330	COG3132	Protein of unknown function, DUF480
XcfCFBP6989P_RS21345	COG0210	DNA helicase
XcfCFBP6989P_RS21350	COG1435	thymidine kinase activity
XcfCFBP6989P_RS21360	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP6989P_RS21370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP6989P_RS21400	COG3135	benzoate transporter
XcfCFBP6989P_RS21420	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP6989P_RS21430	COG3012	SEC-C Motif Domain Protein
XcfCFBP6989P_RS21435	COG0730	response to heat
XcfCFBP6989P_RS21455	COG0302	gtp cyclohydrolase
XcfCFBP6989P_RS21470	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6989P_RS21480	COG1289	transmembrane transporter activity
XcfCFBP6989P_RS21485	COG0477	Major facilitator Superfamily
XcfCFBP6989P_RS21495	COG0583	DNA-binding transcription factor activity
XcfCFBP6989P_RS21500	COG4221	oxidoreductase activity
XcfCFBP6989P_RS21510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6989P_RS21575	COG0564	pseudouridine synthase activity
XcfCFBP6989P_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6989P_RS21650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP6989P_RS21655	COG1074	ATP-dependent DNA helicase activity
XcfCFBP6989P_RS21660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP6989P_RS21695	COG1127	ABC transporter
XcfCFBP6989P_RS21700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6989P_RS21705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6989P_RS21720	COG2853	Lipoprotein
XcfCFBP6989P_RS21730	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6989P_RS21750	COG0625	glutathione transferase activity
XcfCFBP6989P_RS21760	COG0531	amino acid
XcfCFBP6989P_RS21765	COG3537	Alpha-1,2-mannosidase
XcfCFBP6989P_RS21775	COG3706	GGDEF domain
XcfCFBP6989P_RS21780	COG3835	regulator
XcfCFBP6989P_RS21810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6989P_RS21815	COG0861	Integral membrane protein TerC family
XcfCFBP6989P_RS21825	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP6989P_RS21840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP6989P_RS21855	COG0706	membrane insertase activity
XcfCFBP6989P_RS21860	COG0594	ribonuclease P activity
XcfCFBP6989P_RS21930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP6989P_RS21935	COG4691	Plasmid stability protein
XcfCFBP6989P_RS21940	COG1487	ribonuclease activity
XcfCFBP6989P_RS22005	COG3846	protein secretion by the type IV secretion system
XcfCFBP6989P_RS22020	COG3451	type IV secretory pathway VirB4
XcfCFBP6989P_RS22035	COG4962	Type ii secretion system protein e
XcfCFBP6989P_RS22060	COG3328	transposase activity