locus-tag	class	description
XcfCFBP6990P_RS00030	COG0174	glutamine synthetase
XcfCFBP6990P_RS00035	COG0347	Belongs to the P(II) protein family
XcfCFBP6990P_RS00040	COG0004	ammonium transporteR
XcfCFBP6990P_RS00045	COG3852	Histidine kinase
XcfCFBP6990P_RS00050	COG2204	response regulator
XcfCFBP6990P_RS00055	COG2032	superoxide dismutase activity
XcfCFBP6990P_RS00060	COG2032	superoxide dismutase activity
XcfCFBP6990P_RS00065	COG0346	lactoylglutathione lyase activity
XcfCFBP6990P_RS00075	COG0183	Belongs to the thiolase family
XcfCFBP6990P_RS00110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP6990P_RS00115	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP6990P_RS00120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP6990P_RS00135	COG0028	Belongs to the TPP enzyme family
XcfCFBP6990P_RS00140	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS00165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP6990P_RS00180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6990P_RS00190	COG0596	Alpha beta hydrolase
XcfCFBP6990P_RS00195	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP6990P_RS00200	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6990P_RS00205	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS00215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6990P_RS00245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6990P_RS00255	COG0564	pseudouridine synthase activity
XcfCFBP6990P_RS00275	COG1446	asparaginase
XcfCFBP6990P_RS00280	COG0339	signal peptide processing
XcfCFBP6990P_RS00320	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6990P_RS00325	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS00330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP6990P_RS00335	COG2224	Isocitrate lyase
XcfCFBP6990P_RS00365	COG4770	biotin carboxylase activity
XcfCFBP6990P_RS00370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP6990P_RS00375	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS00445	COG0697	spore germination
XcfCFBP6990P_RS00455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP6990P_RS00460	COG1846	Transcriptional regulator
XcfCFBP6990P_RS00465	COG1764	response to oxidative stress
XcfCFBP6990P_RS00495	COG2130	NADP-dependent
XcfCFBP6990P_RS00510	COG1187	pseudouridine synthase activity
XcfCFBP6990P_RS00525	COG1643	Atp-dependent helicase
XcfCFBP6990P_RS00535	COG4807	Protein conserved in bacteria
XcfCFBP6990P_RS00540	COG2351	hydroxyisourate hydrolase activity
XcfCFBP6990P_RS00545	COG2072	flavoprotein involved in K transport
XcfCFBP6990P_RS00565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP6990P_RS00575	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS00610	COG2252	PERMEase
XcfCFBP6990P_RS00635	COG0084	hydrolase, TatD family'
XcfCFBP6990P_RS00645	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS00650	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS00660	COG2267	carboxylic ester hydrolase activity
XcfCFBP6990P_RS00665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP6990P_RS00670	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6990P_RS00690	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS00695	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS00700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS00725	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6990P_RS00730	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS00760	COG0702	epimerase
XcfCFBP6990P_RS00765	COG1733	regulation of RNA biosynthetic process
XcfCFBP6990P_RS00805	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6990P_RS00820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP6990P_RS00875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP6990P_RS00880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP6990P_RS00905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP6990P_RS00910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP6990P_RS00920	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6990P_RS00925	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6990P_RS00935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6990P_RS00940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP6990P_RS00950	COG1414	Transcriptional regulator
XcfCFBP6990P_RS00960	COG0657	acetylesterase activity
XcfCFBP6990P_RS00970	COG0445	tRNA wobble uridine modification
XcfCFBP6990P_RS00980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP6990P_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS01010	COG2267	carboxylic ester hydrolase activity
XcfCFBP6990P_RS01020	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6990P_RS01025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP6990P_RS01030	COG1040	competence protein
XcfCFBP6990P_RS01035	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6990P_RS01080	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6990P_RS01130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP6990P_RS01205	COG1511	domain protein
XcfCFBP6990P_RS01205	COG3264	Mechanosensitive ion channel
XcfCFBP6990P_RS01210	COG1368	sulfuric ester hydrolase activity
XcfCFBP6990P_RS01220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6990P_RS01225	COG2354	Protein conserved in bacteria
XcfCFBP6990P_RS01235	COG0297	glycogen (starch) synthase activity
XcfCFBP6990P_RS01240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6990P_RS01245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6990P_RS01270	COG0702	epimerase
XcfCFBP6990P_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS01310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS01315	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS01325	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6990P_RS01335	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6990P_RS01350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP6990P_RS01360	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP6990P_RS01365	COG3104	oligopeptide transport
XcfCFBP6990P_RS01385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcfCFBP6990P_RS01405	COG1320	monovalent cation:proton antiporter activity
XcfCFBP6990P_RS01410	COG2212	antiporter activity
XcfCFBP6990P_RS01420	COG0651	ATP synthesis coupled electron transport
XcfCFBP6990P_RS01425	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP6990P_RS01430	COG2111	Na H antiporter
XcfCFBP6990P_RS01430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6990P_RS01455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP6990P_RS01460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP6990P_RS01475	COG0456	acetyltransferase
XcfCFBP6990P_RS01480	COG1597	lipid kinase activity
XcfCFBP6990P_RS01510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP6990P_RS01515	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP6990P_RS01525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6990P_RS01530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP6990P_RS01540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP6990P_RS01550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP6990P_RS01565	COG1051	belongs to the nudix hydrolase family
XcfCFBP6990P_RS01605	COG0316	Belongs to the HesB IscA family
XcfCFBP6990P_RS01620	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6990P_RS01640	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS01650	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS01655	COG1289	transmembrane transporter activity
XcfCFBP6990P_RS01660	COG0151	Belongs to the GarS family
XcfCFBP6990P_RS01670	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP6990P_RS01675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6990P_RS01680	COG2267	carboxylic ester hydrolase activity
XcfCFBP6990P_RS01685	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6990P_RS01685	COG2453	phosphatase
XcfCFBP6990P_RS01710	COG4589	Belongs to the CDS family
XcfCFBP6990P_RS01715	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP6990P_RS01740	COG2264	protein methyltransferase activity
XcfCFBP6990P_RS01760	COG0439	Biotin carboxylase
XcfCFBP6990P_RS01770	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP6990P_RS01775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP6990P_RS01785	COG1324	tolerance protein
XcfCFBP6990P_RS01795	COG2356	endonuclease I
XcfCFBP6990P_RS01805	COG0459	protein refolding
XcfCFBP6990P_RS01820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP6990P_RS01835	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6990P_RS01845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP6990P_RS01850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6990P_RS01875	COG0778	Nitroreductase
XcfCFBP6990P_RS01880	COG2353	YceI-like domain
XcfCFBP6990P_RS01910	COG3052	prosthetic group binding
XcfCFBP6990P_RS01935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6990P_RS01945	COG1802	Transcriptional regulator
XcfCFBP6990P_RS02115	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6990P_RS02140	COG4221	oxidoreductase activity
XcfCFBP6990P_RS02155	COG4221	oxidoreductase activity
XcfCFBP6990P_RS02165	COG0435	Glutathione S-transferase
XcfCFBP6990P_RS02200	COG1506	peptidase
XcfCFBP6990P_RS02200	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6990P_RS02240	COG0697	spore germination
XcfCFBP6990P_RS02260	COG1113	amino acid transport
XcfCFBP6990P_RS02280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP6990P_RS02330	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS02335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6990P_RS02335	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6990P_RS02340	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6990P_RS02365	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP6990P_RS02375	COG3275	phosphorelay sensor kinase activity
XcfCFBP6990P_RS02385	COG0181	hydroxymethylbilane synthase activity
XcfCFBP6990P_RS02415	COG1505	serine-type exopeptidase activity
XcfCFBP6990P_RS02420	COG0436	Aminotransferase
XcfCFBP6990P_RS02430	COG2832	Protein of unknown function (DUF454)
XcfCFBP6990P_RS02440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP6990P_RS02450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP6990P_RS02455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP6990P_RS02460	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP6990P_RS02485	COG2226	methyltransferase
XcfCFBP6990P_RS02490	COG5001	Diguanylate cyclase
XcfCFBP6990P_RS02490	COG3300	MHYT domain
XcfCFBP6990P_RS02495	COG0308	aminopeptidase N
XcfCFBP6990P_RS02545	COG3284	Transcriptional regulator
XcfCFBP6990P_RS02550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6990P_RS02555	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6990P_RS02560	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP6990P_RS02575	COG0772	Belongs to the SEDS family
XcfCFBP6990P_RS02585	COG2951	lytic endotransglycosylase activity
XcfCFBP6990P_RS02590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP6990P_RS02600	COG1686	Belongs to the peptidase S11 family
XcfCFBP6990P_RS02610	COG2921	Belongs to the UPF0250 family
XcfCFBP6990P_RS02615	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP6990P_RS02620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP6990P_RS02635	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS02645	COG1051	belongs to the nudix hydrolase family
XcfCFBP6990P_RS02645	COG1056	cytidyltransferase-related domain
XcfCFBP6990P_RS02680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP6990P_RS02685	COG0673	inositol 2-dehydrogenase activity
XcfCFBP6990P_RS02690	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP6990P_RS02695	COG4251	negative regulation of phosphorylation
XcfCFBP6990P_RS02700	COG0784	Response regulator, receiver
XcfCFBP6990P_RS02705	COG4191	Histidine kinase
XcfCFBP6990P_RS02710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP6990P_RS02770	COG1459	type II secretion system
XcfCFBP6990P_RS02775	COG2165	general secretion pathway protein
XcfCFBP6990P_RS02790	COG4795	General secretion pathway protein
XcfCFBP6990P_RS02820	COG3250	beta-galactosidase activity
XcfCFBP6990P_RS02835	COG2188	Transcriptional regulator
XcfCFBP6990P_RS02845	COG1609	Transcriptional regulator
XcfCFBP6990P_RS02850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6990P_RS02855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP6990P_RS02870	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP6990P_RS02875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6990P_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6990P_RS02885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP6990P_RS02900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6990P_RS02915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP6990P_RS02920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6990P_RS02940	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS02970	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP6990P_RS02985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6990P_RS02995	COG0697	spore germination
XcfCFBP6990P_RS03005	COG0488	(ABC) transporter
XcfCFBP6990P_RS03015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP6990P_RS03020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP6990P_RS03030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6990P_RS03030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6990P_RS03050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP6990P_RS03055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6990P_RS03060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP6990P_RS03090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP6990P_RS03095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP6990P_RS03100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP6990P_RS03105	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS03110	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS03125	COG0277	FAD linked oxidase domain protein
XcfCFBP6990P_RS03130	COG1988	membrane-bound metal-dependent
XcfCFBP6990P_RS03135	COG0792	nuclease activity
XcfCFBP6990P_RS03170	COG0275	rRNA processing
XcfCFBP6990P_RS03175	COG3116	cell division
XcfCFBP6990P_RS03190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP6990P_RS03195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP6990P_RS03200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6990P_RS03210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP6990P_RS03215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6990P_RS03220	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6990P_RS03225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP6990P_RS03240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP6990P_RS03250	COG0739	heme binding
XcfCFBP6990P_RS03255	COG0653	protein targeting
XcfCFBP6990P_RS03260	COG0494	nUDIX hydrolase
XcfCFBP6990P_RS03270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP6990P_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS03285	COG0604	alcohol dehydrogenase
XcfCFBP6990P_RS03285	COG3321	synthase
XcfCFBP6990P_RS03305	COG0366	Alpha amylase catalytic
XcfCFBP6990P_RS03340	COG2226	methyltransferase
XcfCFBP6990P_RS03345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP6990P_RS03355	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP6990P_RS03395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP6990P_RS03405	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6990P_RS03410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6990P_RS03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6990P_RS03425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP6990P_RS03435	COG0667	Aldo Keto reductase
XcfCFBP6990P_RS03445	COG4771	TonB-dependent receptor
XcfCFBP6990P_RS03465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6990P_RS03470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP6990P_RS03480	COG2175	clavaminate synthase activity
XcfCFBP6990P_RS03490	COG4181	ATPase activity
XcfCFBP6990P_RS03505	COG0642	Histidine kinase
XcfCFBP6990P_RS03515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP6990P_RS03535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP6990P_RS03540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP6990P_RS03555	COG3829	transcription factor binding
XcfCFBP6990P_RS03565	COG1116	anion transmembrane transporter activity
XcfCFBP6990P_RS03570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6990P_RS03580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6990P_RS03585	COG0431	NADPH-dependent FMN reductase
XcfCFBP6990P_RS03605	COG0747	negative chemotaxis
XcfCFBP6990P_RS03615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP6990P_RS03625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP6990P_RS03630	COG2967	ApaG domain
XcfCFBP6990P_RS03635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP6990P_RS03640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP6990P_RS03645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6990P_RS03650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP6990P_RS03665	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP6990P_RS03670	COG2096	Adenosyltransferase
XcfCFBP6990P_RS03685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6990P_RS03690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6990P_RS03720	COG3384	dioxygenase
XcfCFBP6990P_RS03725	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS03740	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS03775	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP6990P_RS03800	COG0697	spore germination
XcfCFBP6990P_RS03810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6990P_RS03840	COG2197	response regulator
XcfCFBP6990P_RS03850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP6990P_RS03860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP6990P_RS03865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6990P_RS03875	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS03880	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP6990P_RS03890	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6990P_RS03915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6990P_RS03915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6990P_RS03945	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP6990P_RS03990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6990P_RS04000	COG1404	Belongs to the peptidase S8 family
XcfCFBP6990P_RS04005	COG1404	Belongs to the peptidase S8 family
XcfCFBP6990P_RS04010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP6990P_RS04035	COG1295	ribonuclease BN
XcfCFBP6990P_RS04040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6990P_RS04045	COG1254	Belongs to the acylphosphatase family
XcfCFBP6990P_RS04060	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP6990P_RS04070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP6990P_RS04075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP6990P_RS04085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP6990P_RS04090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP6990P_RS04100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP6990P_RS04105	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP6990P_RS04110	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP6990P_RS04115	COG0012	GTP binding
XcfCFBP6990P_RS04135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6990P_RS04150	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP6990P_RS04155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP6990P_RS04160	COG0081	regulation of translation
XcfCFBP6990P_RS04165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP6990P_RS04170	COG0222	ribosome binding
XcfCFBP6990P_RS04175	COG0085	RNA polymerase activity
XcfCFBP6990P_RS04180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP6990P_RS04185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP6990P_RS04190	COG0049	tRNA binding
XcfCFBP6990P_RS04195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP6990P_RS04200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6990P_RS04205	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP6990P_RS04210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP6990P_RS04215	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP6990P_RS04220	COG0089	rRNA binding
XcfCFBP6990P_RS04225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP6990P_RS04230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP6990P_RS04240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP6990P_RS04245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP6990P_RS04250	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP6990P_RS04255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP6990P_RS04265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP6990P_RS04270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP6990P_RS04275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XcfCFBP6990P_RS04280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP6990P_RS04285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP6990P_RS04290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP6990P_RS04300	COG1841	ribosomal large subunit assembly
XcfCFBP6990P_RS04305	COG0200	Binds to the 23S rRNA
XcfCFBP6990P_RS04310	COG0201	protein transport
XcfCFBP6990P_RS04335	COG0203	ribosomal protein L17
XcfCFBP6990P_RS04340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP6990P_RS04360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP6990P_RS04375	COG0154	amidase activity
XcfCFBP6990P_RS04385	COG1217	gtp-binding protein TYPA
XcfCFBP6990P_RS04390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP6990P_RS04395	COG0039	L-malate dehydrogenase activity
XcfCFBP6990P_RS04400	COG0625	glutathione transferase activity
XcfCFBP6990P_RS04415	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6990P_RS04415	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP6990P_RS04420	COG0604	alcohol dehydrogenase
XcfCFBP6990P_RS04450	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6990P_RS04455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcfCFBP6990P_RS04460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP6990P_RS04465	COG4208	sulfate ABC transporter
XcfCFBP6990P_RS04470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP6990P_RS04500	COG0406	alpha-ribazole phosphatase activity
XcfCFBP6990P_RS04505	COG0285	dihydrofolate synthase activity
XcfCFBP6990P_RS04525	COG2833	Protein of unknown function (DUF455)
XcfCFBP6990P_RS04535	COG3291	Pkd domain containing protein
XcfCFBP6990P_RS04545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6990P_RS04550	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6990P_RS04555	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS04565	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP6990P_RS04580	COG4783	chaperone-mediated protein folding
XcfCFBP6990P_RS04595	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6990P_RS04690	COG3328	transposase activity
XcfCFBP6990P_RS04815	COG3179	chitinase
XcfCFBP6990P_RS04860	COG4695	Portal protein
XcfCFBP6990P_RS04890	COG3328	transposase activity
XcfCFBP6990P_RS04905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6990P_RS04930	COG3852	Histidine kinase
XcfCFBP6990P_RS04940	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP6990P_RS04950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP6990P_RS04980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6990P_RS04995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6990P_RS05005	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP6990P_RS05010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6990P_RS05015	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6990P_RS05030	COG0859	PFAM glycosyl transferase family 9
XcfCFBP6990P_RS05035	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP6990P_RS05040	COG1234	tRNA 3'-trailer cleavage
XcfCFBP6990P_RS05045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP6990P_RS05055	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP6990P_RS05060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP6990P_RS05065	COG0314	molybdopterin synthase activity
XcfCFBP6990P_RS05085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP6990P_RS05090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP6990P_RS05095	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP6990P_RS05115	COG0714	Associated with various cellular activities
XcfCFBP6990P_RS05140	COG0424	maF-like protein
XcfCFBP6990P_RS05145	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP6990P_RS05155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6990P_RS05165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6990P_RS05185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP6990P_RS05190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP6990P_RS05215	COG3829	transcription factor binding
XcfCFBP6990P_RS05260	COG2373	Large extracellular alpha-helical protein
XcfCFBP6990P_RS05280	COG4953	penicillin-binding protein 1C
XcfCFBP6990P_RS05290	COG0678	peroxiredoxin activity
XcfCFBP6990P_RS05310	COG0330	HflC and HflK could
XcfCFBP6990P_RS05315	COG0330	HflC and HflK could
XcfCFBP6990P_RS05330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP6990P_RS05335	COG0308	aminopeptidase N
XcfCFBP6990P_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS05345	COG1309	transcriptional regulator
XcfCFBP6990P_RS05440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6990P_RS05450	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6990P_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS05465	COG3537	Alpha-1,2-mannosidase
XcfCFBP6990P_RS05470	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS05485	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6990P_RS05515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6990P_RS05520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6990P_RS05525	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6990P_RS05560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6990P_RS05575	COG0587	DNA-directed DNA polymerase activity
XcfCFBP6990P_RS05590	COG1297	OPT oligopeptide transporter protein
XcfCFBP6990P_RS05610	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6990P_RS05610	COG1506	peptidase
XcfCFBP6990P_RS05625	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP6990P_RS05625	COG2207	Transcriptional regulator
XcfCFBP6990P_RS05650	COG0753	catalase activity
XcfCFBP6990P_RS05655	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP6990P_RS05665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6990P_RS05665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6990P_RS05670	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS05685	COG2194	sulfuric ester hydrolase activity
XcfCFBP6990P_RS05700	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS05705	COG0642	Histidine kinase
XcfCFBP6990P_RS05715	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP6990P_RS05720	COG2894	cell division
XcfCFBP6990P_RS05725	COG0850	regulation of cytokinetic process
XcfCFBP6990P_RS05740	COG4585	Histidine kinase
XcfCFBP6990P_RS05745	COG2197	response regulator
XcfCFBP6990P_RS05760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP6990P_RS05785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP6990P_RS05795	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP6990P_RS05815	COG1946	Acyl-CoA thioesterase
XcfCFBP6990P_RS05830	COG0824	Thioesterase
XcfCFBP6990P_RS05835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP6990P_RS05840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP6990P_RS05845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP6990P_RS05850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP6990P_RS05855	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP6990P_RS05865	COG0196	riboflavin kinase activity
XcfCFBP6990P_RS05870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP6990P_RS05875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP6990P_RS05880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP6990P_RS05895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP6990P_RS05900	COG1845	cytochrome c oxidase, subunit III
XcfCFBP6990P_RS05905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP6990P_RS05920	COG3152	Membrane
XcfCFBP6990P_RS05930	COG2207	Transcriptional regulator
XcfCFBP6990P_RS05935	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6990P_RS05945	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6990P_RS05950	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6990P_RS05955	COG2172	sigma factor antagonist activity
XcfCFBP6990P_RS05980	COG4771	TonB-dependent receptor
XcfCFBP6990P_RS05990	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP6990P_RS05995	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS06005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6990P_RS06010	COG3437	response regulator, receiver
XcfCFBP6990P_RS06010	COG3850	Histidine kinase
XcfCFBP6990P_RS06010	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS06010	COG4999	Histidine kinase
XcfCFBP6990P_RS06015	COG0784	Response regulator, receiver
XcfCFBP6990P_RS06015	COG4191	Histidine kinase
XcfCFBP6990P_RS06040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6990P_RS06045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP6990P_RS06055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6990P_RS06060	COG0228	four-way junction DNA binding
XcfCFBP6990P_RS06065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP6990P_RS06070	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP6990P_RS06075	COG0335	large ribosomal subunit rRNA binding
XcfCFBP6990P_RS06080	COG0534	Mate efflux family protein
XcfCFBP6990P_RS06105	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP6990P_RS06115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP6990P_RS06150	COG3250	beta-galactosidase activity
XcfCFBP6990P_RS06155	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP6990P_RS06175	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS06180	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS06215	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6990P_RS06215	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS06230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6990P_RS06235	COG0481	GTPase activity
XcfCFBP6990P_RS06250	COG0571	ribonuclease III activity
XcfCFBP6990P_RS06255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP6990P_RS06260	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP6990P_RS06270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6990P_RS06275	COG2954	triphosphatase activity
XcfCFBP6990P_RS06280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP6990P_RS06285	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP6990P_RS06290	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP6990P_RS06295	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6990P_RS06300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP6990P_RS06305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP6990P_RS06310	COG1278	Cold shock
XcfCFBP6990P_RS06315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6990P_RS06325	COG1201	RNA secondary structure unwinding
XcfCFBP6990P_RS06330	COG1793	dna ligase
XcfCFBP6990P_RS06340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6990P_RS06340	COG1793	dna ligase
XcfCFBP6990P_RS06375	COG0183	Belongs to the thiolase family
XcfCFBP6990P_RS06400	COG1451	nucleotide metabolic process
XcfCFBP6990P_RS06405	COG5487	UPF0391 membrane protein
XcfCFBP6990P_RS06415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6990P_RS06430	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6990P_RS06435	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6990P_RS06445	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP6990P_RS06455	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6990P_RS06460	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS06495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP6990P_RS06495	COG0392	lysyltransferase activity
XcfCFBP6990P_RS06505	COG0251	oxidation-reduction process
XcfCFBP6990P_RS06510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6990P_RS06525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6990P_RS06550	COG1595	DNA-templated transcription, initiation
XcfCFBP6990P_RS06570	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP6990P_RS06580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6990P_RS06580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6990P_RS06595	COG1131	(ABC) transporter
XcfCFBP6990P_RS06600	COG0346	lactoylglutathione lyase activity
XcfCFBP6990P_RS06605	COG0833	amino acid
XcfCFBP6990P_RS06610	COG2040	homocysteine
XcfCFBP6990P_RS06620	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6990P_RS06640	COG1695	Transcriptional regulator
XcfCFBP6990P_RS06660	COG1981	membrane
XcfCFBP6990P_RS06675	COG0825	malonyl-CoA metabolic process
XcfCFBP6990P_RS06690	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6990P_RS06695	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6990P_RS06700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6990P_RS06705	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6990P_RS06720	COG0750	zinc metalloprotease
XcfCFBP6990P_RS06725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP6990P_RS06730	COG0575	Belongs to the CDS family
XcfCFBP6990P_RS06735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP6990P_RS06740	COG0233	cytoplasmic translational termination
XcfCFBP6990P_RS06745	COG0528	UMP kinase activity
XcfCFBP6990P_RS06755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP6990P_RS06760	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP6990P_RS06800	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP6990P_RS06810	COG1393	Belongs to the ArsC family
XcfCFBP6990P_RS06815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6990P_RS06820	COG0367	asparagine synthase
XcfCFBP6990P_RS06830	COG4774	siderophore transport
XcfCFBP6990P_RS06915	COG4397	Mu-like prophage major head subunit gpT
XcfCFBP6990P_RS06935	COG2369	cell adhesion
XcfCFBP6990P_RS06940	COG4383	Mu-like prophage protein gp29
XcfCFBP6990P_RS06945	COG4373	Mu-like prophage FluMu protein gp28
XcfCFBP6990P_RS06965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6990P_RS06990	COG5566	PFAM Mor transcription activator
XcfCFBP6990P_RS07055	COG2842	Transposition protein
XcfCFBP6990P_RS07060	COG2801	Transposase and inactivated derivatives
XcfCFBP6990P_RS07100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6990P_RS07130	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6990P_RS07135	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS07185	COG0339	signal peptide processing
XcfCFBP6990P_RS07195	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6990P_RS07250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP6990P_RS07255	COG0084	hydrolase, TatD family'
XcfCFBP6990P_RS07270	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS07290	COG0367	asparagine synthase
XcfCFBP6990P_RS07300	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6990P_RS07305	COG0415	Belongs to the DNA photolyase family
XcfCFBP6990P_RS07315	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS07360	COG3706	GGDEF domain
XcfCFBP6990P_RS07560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP6990P_RS07575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6990P_RS07585	COG0497	DNA recombination
XcfCFBP6990P_RS07590	COG1420	regulation of RNA biosynthetic process
XcfCFBP6990P_RS07595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP6990P_RS07600	COG0443	Heat shock 70 kDa protein
XcfCFBP6990P_RS07605	COG0484	heat shock protein binding
XcfCFBP6990P_RS07615	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP6990P_RS07645	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS07655	COG1132	(ABC) transporter
XcfCFBP6990P_RS07680	COG0567	Dehydrogenase, E1 component
XcfCFBP6990P_RS07690	COG2850	peptidyl-arginine hydroxylation
XcfCFBP6990P_RS07715	COG1253	flavin adenine dinucleotide binding
XcfCFBP6990P_RS07750	COG1131	(ABC) transporter
XcfCFBP6990P_RS07755	COG1725	Transcriptional regulator
XcfCFBP6990P_RS07765	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6990P_RS07780	COG2900	Belongs to the SlyX family
XcfCFBP6990P_RS07805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6990P_RS07815	COG0646	methionine synthase
XcfCFBP6990P_RS07815	COG1410	methionine synthase
XcfCFBP6990P_RS07820	COG1410	methionine synthase
XcfCFBP6990P_RS07820	COG0646	methionine synthase
XcfCFBP6990P_RS07825	COG2226	methyltransferase
XcfCFBP6990P_RS07830	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS07840	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS07870	COG0557	exoribonuclease II activity
XcfCFBP6990P_RS07880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6990P_RS07890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6990P_RS07900	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP6990P_RS07905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP6990P_RS07910	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP6990P_RS07915	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP6990P_RS07920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP6990P_RS07945	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6990P_RS07950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP6990P_RS07960	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS07970	COG0494	nUDIX hydrolase
XcfCFBP6990P_RS08015	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP6990P_RS08015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6990P_RS08020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP6990P_RS08045	COG2925	Exonuclease
XcfCFBP6990P_RS08050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6990P_RS08055	COG3844	kynureninase activity
XcfCFBP6990P_RS08065	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6990P_RS08070	COG0288	reversible hydration of carbon dioxide
XcfCFBP6990P_RS08150	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP6990P_RS08160	COG0316	Belongs to the HesB IscA family
XcfCFBP6990P_RS08165	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP6990P_RS08170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP6990P_RS08175	COG0359	binds to the 23S rRNA
XcfCFBP6990P_RS08190	COG3115	cell septum assembly
XcfCFBP6990P_RS08200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6990P_RS08205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcfCFBP6990P_RS08210	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP6990P_RS08225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP6990P_RS08235	COG4993	Dehydrogenase
XcfCFBP6990P_RS08245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP6990P_RS08255	COG2986	histidine ammonia-lyase
XcfCFBP6990P_RS08260	COG1228	amidohydrolase
XcfCFBP6990P_RS08300	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP6990P_RS08305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP6990P_RS08310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP6990P_RS08315	COG0077	Prephenate dehydratase
XcfCFBP6990P_RS08315	COG1605	Chorismate mutase
XcfCFBP6990P_RS08320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP6990P_RS08335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP6990P_RS08340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6990P_RS08345	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS08360	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS08395	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP6990P_RS08400	COG0784	Response regulator, receiver
XcfCFBP6990P_RS08400	COG4191	Histidine kinase
XcfCFBP6990P_RS08415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6990P_RS08425	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6990P_RS08435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6990P_RS08450	COG1595	DNA-templated transcription, initiation
XcfCFBP6990P_RS08505	COG2244	polysaccharide biosynthetic process
XcfCFBP6990P_RS08535	COG2264	protein methyltransferase activity
XcfCFBP6990P_RS08560	COG1136	(ABC) transporter
XcfCFBP6990P_RS08570	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS08575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6990P_RS08590	COG1253	flavin adenine dinucleotide binding
XcfCFBP6990P_RS08605	COG0306	phosphate transporter
XcfCFBP6990P_RS08635	COG0504	CTP synthase activity
XcfCFBP6990P_RS08650	COG0148	phosphopyruvate hydratase activity
XcfCFBP6990P_RS08655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP6990P_RS08660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP6990P_RS08665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP6990P_RS08670	COG0585	pseudouridine synthase activity
XcfCFBP6990P_RS08675	COG2840	Smr protein MutS2
XcfCFBP6990P_RS08680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP6990P_RS08685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6990P_RS08690	COG1238	metal cluster binding
XcfCFBP6990P_RS08705	COG1534	Rna-binding protein
XcfCFBP6990P_RS08710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP6990P_RS08720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP6990P_RS08725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP6990P_RS08735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP6990P_RS08740	COG1546	Belongs to the CinA family
XcfCFBP6990P_RS08750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6990P_RS08755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP6990P_RS08765	COG2137	regulation of response to DNA damage stimulus
XcfCFBP6990P_RS08770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP6990P_RS08775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP6990P_RS08800	COG1741	Belongs to the pirin family
XcfCFBP6990P_RS08805	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS08830	COG0351	phosphomethylpyrimidine kinase
XcfCFBP6990P_RS08845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP6990P_RS08850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP6990P_RS08865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6990P_RS08875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP6990P_RS08880	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP6990P_RS08890	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6990P_RS08895	COG0800	Aldolase
XcfCFBP6990P_RS08935	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP6990P_RS08945	COG1070	Carbohydrate kinase
XcfCFBP6990P_RS08950	COG2115	Belongs to the xylose isomerase family
XcfCFBP6990P_RS08955	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS08970	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6990P_RS08975	COG1469	GTP cyclohydrolase I activity
XcfCFBP6990P_RS08995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP6990P_RS09000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP6990P_RS09005	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP6990P_RS09030	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6990P_RS09045	COG3706	GGDEF domain
XcfCFBP6990P_RS09045	COG4251	negative regulation of phosphorylation
XcfCFBP6990P_RS09045	COG5001	Diguanylate cyclase
XcfCFBP6990P_RS09045	COG2203	Gaf domain
XcfCFBP6990P_RS09050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6990P_RS09055	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP6990P_RS09065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP6990P_RS09070	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6990P_RS09085	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP6990P_RS09095	COG0697	spore germination
XcfCFBP6990P_RS09100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP6990P_RS09105	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP6990P_RS09125	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6990P_RS09140	COG3328	transposase activity
XcfCFBP6990P_RS09170	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS09175	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP6990P_RS09175	COG0726	polysaccharide deacetylase
XcfCFBP6990P_RS09205	COG3328	transposase activity
XcfCFBP6990P_RS09240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XcfCFBP6990P_RS09250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6990P_RS09255	COG0124	histidyl-tRNA synthetase
XcfCFBP6990P_RS09265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP6990P_RS09270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP6990P_RS09275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6990P_RS09280	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP6990P_RS09280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP6990P_RS09285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP6990P_RS09290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP6990P_RS09295	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP6990P_RS09300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP6990P_RS09300	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP6990P_RS09315	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP6990P_RS09320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP6990P_RS09325	COG0235	Class ii aldolase
XcfCFBP6990P_RS09330	COG0531	amino acid
XcfCFBP6990P_RS09335	COG0531	amino acid
XcfCFBP6990P_RS09345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP6990P_RS09350	COG0277	FAD linked oxidase domain protein
XcfCFBP6990P_RS09370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6990P_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6990P_RS09425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP6990P_RS09430	COG0505	Belongs to the CarA family
XcfCFBP6990P_RS09440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP6990P_RS09445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6990P_RS09455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP6990P_RS09465	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6990P_RS09475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP6990P_RS09485	COG0784	Response regulator, receiver
XcfCFBP6990P_RS09485	COG2198	Histidine kinase
XcfCFBP6990P_RS09485	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS09490	COG0784	Response regulator, receiver
XcfCFBP6990P_RS09490	COG2198	Histidine kinase
XcfCFBP6990P_RS09490	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS09495	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS09500	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6990P_RS09535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6990P_RS09545	COG2201	protein-glutamate methylesterase activity
XcfCFBP6990P_RS09550	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP6990P_RS09560	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09575	COG0835	chemotaxis
XcfCFBP6990P_RS09605	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09610	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09620	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09630	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09640	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09645	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09650	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09665	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS09690	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS09700	COG0835	chemotaxis
XcfCFBP6990P_RS09710	COG1360	Flagellar Motor Protein
XcfCFBP6990P_RS09715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP6990P_RS09735	COG1192	Involved in chromosome partitioning
XcfCFBP6990P_RS09805	COG2198	Histidine kinase
XcfCFBP6990P_RS09805	COG0784	Response regulator, receiver
XcfCFBP6990P_RS09805	COG0643	Histidine kinase
XcfCFBP6990P_RS09870	COG1684	flagellar biosynthetic protein fliR
XcfCFBP6990P_RS09890	COG3190	flagellar
XcfCFBP6990P_RS09940	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP6990P_RS09975	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS09985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6990P_RS10005	COG2201	protein-glutamate methylesterase activity
XcfCFBP6990P_RS10035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcfCFBP6990P_RS10045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcfCFBP6990P_RS10055	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6990P_RS10055	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6990P_RS10060	COG1706	bacterial-type flagellum-dependent cell motility
XcfCFBP6990P_RS10065	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcfCFBP6990P_RS10075	COG4787	bacterial-type flagellum-dependent cell motility
XcfCFBP6990P_RS10085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcfCFBP6990P_RS10090	COG1558	bacterial-type flagellum-dependent cell motility
XcfCFBP6990P_RS10100	COG0835	chemotaxis
XcfCFBP6990P_RS10100	COG0784	Response regulator, receiver
XcfCFBP6990P_RS10120	COG5002	protein histidine kinase activity
XcfCFBP6990P_RS10150	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP6990P_RS10155	COG0482	sulfurtransferase activity
XcfCFBP6990P_RS10170	COG0542	response to heat
XcfCFBP6990P_RS10180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP6990P_RS10190	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6990P_RS10195	COG1674	ftsk spoiiie
XcfCFBP6990P_RS10205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP6990P_RS10215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP6990P_RS10220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP6990P_RS10230	COG0183	Belongs to the thiolase family
XcfCFBP6990P_RS10235	COG1024	Enoyl-CoA hydratase
XcfCFBP6990P_RS10235	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6990P_RS10250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP6990P_RS10260	COG1426	Protein conserved in bacteria
XcfCFBP6990P_RS10270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6990P_RS10275	COG1160	GTP binding
XcfCFBP6990P_RS10280	COG0303	'Molybdopterin
XcfCFBP6990P_RS10285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP6990P_RS10325	COG0708	Exodeoxyribonuclease III
XcfCFBP6990P_RS10335	COG0303	'Molybdopterin
XcfCFBP6990P_RS10340	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP6990P_RS10370	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP6990P_RS10385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcfCFBP6990P_RS10390	COG0668	transmembrane transport
XcfCFBP6990P_RS10400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP6990P_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS10420	COG1183	phosphatidylcholine synthase activity
XcfCFBP6990P_RS10430	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP6990P_RS10445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6990P_RS10445	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6990P_RS10455	COG2183	response to ionizing radiation
XcfCFBP6990P_RS10460	COG0784	Response regulator, receiver
XcfCFBP6990P_RS10460	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS10520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS10530	COG0800	Aldolase
XcfCFBP6990P_RS10535	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6990P_RS10540	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP6990P_RS10545	COG0837	glucose binding
XcfCFBP6990P_RS10550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6990P_RS10560	COG0354	folic acid binding
XcfCFBP6990P_RS10575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP6990P_RS10590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP6990P_RS10595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP6990P_RS10605	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP6990P_RS10610	COG1136	(ABC) transporter
XcfCFBP6990P_RS10625	COG0811	peptide transport
XcfCFBP6990P_RS10630	COG0848	biopolymer transport protein
XcfCFBP6990P_RS10635	COG1132	(ABC) transporter
XcfCFBP6990P_RS10640	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP6990P_RS10645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP6990P_RS10650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP6990P_RS10660	COG0322	excinuclease ABC activity
XcfCFBP6990P_RS10665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6990P_RS10690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP6990P_RS10710	COG1054	Belongs to the UPF0176 family
XcfCFBP6990P_RS10720	COG1530	ribonuclease E activity
XcfCFBP6990P_RS10730	COG3064	Membrane
XcfCFBP6990P_RS10735	COG0428	transporter
XcfCFBP6990P_RS10745	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP6990P_RS10750	COG0316	Belongs to the HesB IscA family
XcfCFBP6990P_RS10750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP6990P_RS10800	COG2226	methyltransferase
XcfCFBP6990P_RS10800	COG1073	alpha beta
XcfCFBP6990P_RS10805	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6990P_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS10820	COG5599	Phosphatase
XcfCFBP6990P_RS10865	COG2951	lytic endotransglycosylase activity
XcfCFBP6990P_RS10895	COG3220	belongs to the UPF0276 family
XcfCFBP6990P_RS10920	COG3920	Histidine kinase
XcfCFBP6990P_RS10930	COG1238	metal cluster binding
XcfCFBP6990P_RS10960	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6990P_RS11005	COG4566	intracellular signal transduction
XcfCFBP6990P_RS11015	COG5001	Diguanylate cyclase
XcfCFBP6990P_RS11035	COG3685	Protein conserved in bacteria
XcfCFBP6990P_RS11055	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6990P_RS11055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6990P_RS11070	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS11085	COG1335	isochorismatase
XcfCFBP6990P_RS11100	COG2197	response regulator
XcfCFBP6990P_RS11115	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS11120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6990P_RS11125	COG3002	Belongs to the UPF0753 family
XcfCFBP6990P_RS11130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6990P_RS11130	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6990P_RS11140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP6990P_RS11155	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6990P_RS11155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6990P_RS11165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP6990P_RS11175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6990P_RS11180	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP6990P_RS11190	COG0776	regulation of translation
XcfCFBP6990P_RS11195	COG0539	negative regulation of cytoplasmic translation
XcfCFBP6990P_RS11200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP6990P_RS11220	COG2957	Belongs to the agmatine deiminase family
XcfCFBP6990P_RS11225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6990P_RS11250	COG0395	ABC-type sugar transport system, permease component
XcfCFBP6990P_RS11255	COG1175	transmembrane transport
XcfCFBP6990P_RS11285	COG2350	Protein conserved in bacteria
XcfCFBP6990P_RS11290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP6990P_RS11295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP6990P_RS11300	COG1187	pseudouridine synthase activity
XcfCFBP6990P_RS11325	COG0436	Aminotransferase
XcfCFBP6990P_RS11330	COG4133	protoheme IX ABC transporter activity
XcfCFBP6990P_RS11350	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6990P_RS11355	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP6990P_RS11375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6990P_RS11380	COG1278	Cold shock
XcfCFBP6990P_RS11385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP6990P_RS11390	COG4988	ABC transporter
XcfCFBP6990P_RS11400	COG1294	oxidase, subunit
XcfCFBP6990P_RS11430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP6990P_RS11435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP6990P_RS11445	COG0165	Argininosuccinate lyase
XcfCFBP6990P_RS11450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP6990P_RS11460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP6990P_RS11465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6990P_RS11475	COG0137	argininosuccinate synthase activity
XcfCFBP6990P_RS11480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP6990P_RS11490	COG0215	cysteine-tRNA ligase activity
XcfCFBP6990P_RS11495	COG2166	iron-sulfur cluster assembly
XcfCFBP6990P_RS11510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP6990P_RS11515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP6990P_RS11535	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP6990P_RS11585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP6990P_RS11590	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6990P_RS11600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6990P_RS11610	COG5001	Diguanylate cyclase
XcfCFBP6990P_RS11610	COG3300	MHYT domain
XcfCFBP6990P_RS11625	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP6990P_RS11630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP6990P_RS11650	COG0488	(ABC) transporter
XcfCFBP6990P_RS11655	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6990P_RS11660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP6990P_RS11665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP6990P_RS11675	COG0625	glutathione transferase activity
XcfCFBP6990P_RS11685	COG4681	YaeQ
XcfCFBP6990P_RS11690	COG2081	HI0933 family
XcfCFBP6990P_RS11700	COG0501	Belongs to the peptidase M48B family
XcfCFBP6990P_RS11705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6990P_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS11735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP6990P_RS11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6990P_RS11745	COG0802	atpase or kinase
XcfCFBP6990P_RS11750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6990P_RS11750	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP6990P_RS11755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6990P_RS11760	COG1570	exodeoxyribonuclease VII activity
XcfCFBP6990P_RS11775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6990P_RS11815	COG0582	viral genome integration into host DNA
XcfCFBP6990P_RS12005	COG3328	transposase activity
XcfCFBP6990P_RS12020	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6990P_RS12105	COG3723	Recombinational DNA repair protein, rece pathway
XcfCFBP6990P_RS12140	COG0835	chemotaxis
XcfCFBP6990P_RS12145	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS12150	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP6990P_RS12155	COG1201	RNA secondary structure unwinding
XcfCFBP6990P_RS12180	COG2969	positive regulation of protein catabolic process
XcfCFBP6990P_RS12185	COG0625	glutathione transferase activity
XcfCFBP6990P_RS12190	COG2857	Cytochrome c1
XcfCFBP6990P_RS12195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP6990P_RS12200	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6990P_RS12210	COG0741	lytic transglycosylase activity
XcfCFBP6990P_RS12225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6990P_RS12230	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP6990P_RS12240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP6990P_RS12250	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP6990P_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6990P_RS12270	COG1177	transmembrane transport
XcfCFBP6990P_RS12275	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP6990P_RS12285	COG3842	ATPase activity
XcfCFBP6990P_RS12305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP6990P_RS12325	COG0174	glutamine synthetase
XcfCFBP6990P_RS12330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6990P_RS12340	COG2703	oxygen carrier activity
XcfCFBP6990P_RS12345	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS12360	COG0243	molybdopterin cofactor binding
XcfCFBP6990P_RS12365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP6990P_RS12370	COG2223	nitrite transmembrane transporter activity
XcfCFBP6990P_RS12385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP6990P_RS12395	COG2733	membrane
XcfCFBP6990P_RS12400	COG0784	Response regulator, receiver
XcfCFBP6990P_RS12400	COG5002	protein histidine kinase activity
XcfCFBP6990P_RS12400	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS12420	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS12425	COG2902	Dehydrogenase
XcfCFBP6990P_RS12435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS12440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS12445	COG1609	Transcriptional regulator
XcfCFBP6990P_RS12450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6990P_RS12450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6990P_RS12455	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP6990P_RS12460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6990P_RS12460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6990P_RS12495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP6990P_RS12505	COG1862	Preprotein translocase
XcfCFBP6990P_RS12510	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP6990P_RS12515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP6990P_RS12550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP6990P_RS12555	COG3291	Pkd domain containing protein
XcfCFBP6990P_RS12560	COG0405	Gamma-glutamyltransferase
XcfCFBP6990P_RS12565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP6990P_RS12575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP6990P_RS12580	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP6990P_RS12585	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6990P_RS12690	COG0531	amino acid
XcfCFBP6990P_RS12705	COG0006	proline dipeptidase activity
XcfCFBP6990P_RS12715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6990P_RS12730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6990P_RS12735	COG3938	Belongs to the proline racemase family
XcfCFBP6990P_RS12745	COG0552	protein localization to endoplasmic reticulum
XcfCFBP6990P_RS12755	COG1194	a g-specific adenine glycosylase
XcfCFBP6990P_RS12760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP6990P_RS12765	COG0784	Response regulator, receiver
XcfCFBP6990P_RS12765	COG4191	Histidine kinase
XcfCFBP6990P_RS12780	COG0322	excinuclease ABC activity
XcfCFBP6990P_RS12795	COG3040	lipid binding
XcfCFBP6990P_RS12805	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS12815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP6990P_RS12835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6990P_RS12840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6990P_RS12845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6990P_RS12870	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS12880	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS12885	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS12935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6990P_RS12935	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP6990P_RS12940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP6990P_RS12955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP6990P_RS12960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP6990P_RS12975	COG2211	Major facilitator Superfamily
XcfCFBP6990P_RS12975	COG2190	(PTS) system
XcfCFBP6990P_RS12985	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6990P_RS13000	COG0366	Alpha amylase catalytic
XcfCFBP6990P_RS13045	COG3702	type iv secretory pathway
XcfCFBP6990P_RS13065	COG2948	multi-organism process
XcfCFBP6990P_RS13085	COG3505	Type IV secretory pathway VirD4
XcfCFBP6990P_RS13095	COG0582	viral genome integration into host DNA
XcfCFBP6990P_RS13105	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XcfCFBP6990P_RS13225	COG0556	nucleotide-excision repair
XcfCFBP6990P_RS13230	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6990P_RS13265	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6990P_RS13270	COG1611	Belongs to the LOG family
XcfCFBP6990P_RS13285	COG2095	MarC family integral membrane protein
XcfCFBP6990P_RS13295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6990P_RS13330	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP6990P_RS13335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP6990P_RS13340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP6990P_RS13345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP6990P_RS13350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP6990P_RS13355	COG0195	Participates in both transcription termination and antitermination
XcfCFBP6990P_RS13360	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP6990P_RS13370	COG1007	ATP synthesis coupled electron transport
XcfCFBP6990P_RS13395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6990P_RS13400	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP6990P_RS13410	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP6990P_RS13415	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP6990P_RS13420	COG0649	NAD binding
XcfCFBP6990P_RS13425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6990P_RS13430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6990P_RS13435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6990P_RS13450	COG0149	triose-phosphate isomerase activity
XcfCFBP6990P_RS13455	COG0300	oxidoreductase activity
XcfCFBP6990P_RS13485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6990P_RS13490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP6990P_RS13495	COG0159	tryptophan synthase activity
XcfCFBP6990P_RS13505	COG0133	tryptophan synthase activity
XcfCFBP6990P_RS13515	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP6990P_RS13520	COG0101	tRNA pseudouridine synthase activity
XcfCFBP6990P_RS13535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP6990P_RS13540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP6990P_RS13545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP6990P_RS13550	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6990P_RS13560	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP6990P_RS13575	COG0433	COG0433 Predicted ATPase
XcfCFBP6990P_RS13580	COG0494	nUDIX hydrolase
XcfCFBP6990P_RS13595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6990P_RS13600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6990P_RS13625	COG0717	Belongs to the dCTP deaminase family
XcfCFBP6990P_RS13635	COG0489	protein tyrosine kinase activity
XcfCFBP6990P_RS13655	COG3590	peptidase
XcfCFBP6990P_RS13660	COG3590	peptidase
XcfCFBP6990P_RS13680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6990P_RS13685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6990P_RS13690	COG2311	Membrane
XcfCFBP6990P_RS13695	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6990P_RS13700	COG0791	NLP P60 protein
XcfCFBP6990P_RS13705	COG0791	NLP P60 protein
XcfCFBP6990P_RS13715	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6990P_RS13720	COG1301	dicarboxylic acid transport
XcfCFBP6990P_RS13725	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP6990P_RS13735	COG0037	tRNA processing
XcfCFBP6990P_RS13740	COG1722	exodeoxyribonuclease VII activity
XcfCFBP6990P_RS13745	COG0142	geranyltranstransferase activity
XcfCFBP6990P_RS13750	COG4104	PAAR repeat-containing protein
XcfCFBP6990P_RS13760	COG0312	modulator of DNA gyrase
XcfCFBP6990P_RS13765	COG3028	Belongs to the UPF0307 family
XcfCFBP6990P_RS13770	COG0312	modulator of DNA gyrase
XcfCFBP6990P_RS13780	COG3164	Protein of unknown function
XcfCFBP6990P_RS13790	COG0424	maF-like protein
XcfCFBP6990P_RS13795	COG2968	Membrane
XcfCFBP6990P_RS13810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP6990P_RS13825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP6990P_RS13840	COG0495	leucyl-tRNA aminoacylation
XcfCFBP6990P_RS13850	COG3118	belongs to the thioredoxin family
XcfCFBP6990P_RS13885	COG2155	Conserved Protein
XcfCFBP6990P_RS13930	COG1132	(ABC) transporter
XcfCFBP6990P_RS13955	COG1538	Outer membrane efflux protein
XcfCFBP6990P_RS13960	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS13965	COG5000	phosphorelay sensor kinase activity
XcfCFBP6990P_RS13965	COG5002	protein histidine kinase activity
XcfCFBP6990P_RS13970	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6990P_RS13980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6990P_RS14000	COG1187	pseudouridine synthase activity
XcfCFBP6990P_RS14005	COG5002	protein histidine kinase activity
XcfCFBP6990P_RS14005	COG5001	Diguanylate cyclase
XcfCFBP6990P_RS14015	COG1595	DNA-templated transcription, initiation
XcfCFBP6990P_RS14125	COG2951	lytic endotransglycosylase activity
XcfCFBP6990P_RS14180	COG0667	Aldo Keto reductase
XcfCFBP6990P_RS14185	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS14190	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS14200	COG2207	Transcriptional regulator
XcfCFBP6990P_RS14210	COG1309	transcriptional regulator
XcfCFBP6990P_RS14220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS14235	COG0735	belongs to the Fur family
XcfCFBP6990P_RS14240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6990P_RS14265	COG4452	Inner membrane protein CreD
XcfCFBP6990P_RS14275	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS14280	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS14285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP6990P_RS14295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP6990P_RS14305	COG2198	Histidine kinase
XcfCFBP6990P_RS14305	COG0643	Histidine kinase
XcfCFBP6990P_RS14310	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS14315	COG0835	chemotaxis
XcfCFBP6990P_RS14320	COG2199	diguanylate cyclase activity
XcfCFBP6990P_RS14320	COG2200	EAL domain
XcfCFBP6990P_RS14320	COG2202	Pas domain
XcfCFBP6990P_RS14325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6990P_RS14335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6990P_RS14340	COG3590	peptidase
XcfCFBP6990P_RS14350	COG0588	phosphoglycerate mutase activity
XcfCFBP6990P_RS14355	COG1515	deoxyribonuclease V activity
XcfCFBP6990P_RS14365	COG1741	Belongs to the pirin family
XcfCFBP6990P_RS14380	COG1741	Belongs to the pirin family
XcfCFBP6990P_RS14385	COG1966	Carbon starvation protein
XcfCFBP6990P_RS14390	COG2879	small protein
XcfCFBP6990P_RS14440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP6990P_RS14445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6990P_RS14450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6990P_RS14455	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6990P_RS14460	COG0604	alcohol dehydrogenase
XcfCFBP6990P_RS14460	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS14460	COG3321	synthase
XcfCFBP6990P_RS14470	COG0629	single-stranded DNA binding
XcfCFBP6990P_RS14475	COG0142	geranyltranstransferase activity
XcfCFBP6990P_RS14490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP6990P_RS14505	COG0527	aspartate kinase activity
XcfCFBP6990P_RS14510	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6990P_RS14515	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6990P_RS14525	COG1764	response to oxidative stress
XcfCFBP6990P_RS14530	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6990P_RS14535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6990P_RS14540	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6990P_RS14550	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6990P_RS14580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP6990P_RS14595	COG0739	heme binding
XcfCFBP6990P_RS14615	COG0693	protein deglycase activity
XcfCFBP6990P_RS14625	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP6990P_RS14630	COG0719	Fe-S assembly protein
XcfCFBP6990P_RS14635	COG0396	ATPase activity
XcfCFBP6990P_RS14640	COG0719	Fe-S assembly protein
XcfCFBP6990P_RS14645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP6990P_RS14655	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP6990P_RS14665	COG3128	pkhd-type hydroxylase
XcfCFBP6990P_RS14690	COG1477	protein flavinylation
XcfCFBP6990P_RS14695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6990P_RS14705	COG1555	photosystem II stabilization
XcfCFBP6990P_RS14720	COG3178	'Phosphotransferase
XcfCFBP6990P_RS14725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP6990P_RS14745	COG0628	permease
XcfCFBP6990P_RS14755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP6990P_RS14765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP6990P_RS14785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP6990P_RS14790	COG0271	Belongs to the BolA IbaG family
XcfCFBP6990P_RS14800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP6990P_RS14810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP6990P_RS14815	COG1137	ATPase activity
XcfCFBP6990P_RS14830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6990P_RS14835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP6990P_RS14840	COG1660	Displays ATPase and GTPase activities
XcfCFBP6990P_RS14850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6990P_RS14855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6990P_RS14865	COG2239	Acts as a magnesium transporter
XcfCFBP6990P_RS14875	COG1294	oxidase, subunit
XcfCFBP6990P_RS14880	COG1271	oxidase subunit
XcfCFBP6990P_RS14890	COG1113	amino acid transport
XcfCFBP6990P_RS14920	COG2197	response regulator
XcfCFBP6990P_RS14925	COG0531	amino acid
XcfCFBP6990P_RS15035	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS15045	COG0754	glutathionylspermidine amidase activity
XcfCFBP6990P_RS15070	COG1842	Phage shock protein A
XcfCFBP6990P_RS15080	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP6990P_RS15085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP6990P_RS15090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP6990P_RS15100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP6990P_RS15105	COG2814	Major facilitator Superfamily
XcfCFBP6990P_RS15125	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS15125	COG2198	Histidine kinase
XcfCFBP6990P_RS15125	COG0784	Response regulator, receiver
XcfCFBP6990P_RS15130	COG2353	YceI-like domain
XcfCFBP6990P_RS15150	COG1760	l-serine dehydratase
XcfCFBP6990P_RS15165	COG0527	aspartate kinase activity
XcfCFBP6990P_RS15165	COG0460	homoserine dehydrogenase
XcfCFBP6990P_RS15170	COG0626	cystathionine gamma-synthase activity
XcfCFBP6990P_RS15175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6990P_RS15180	COG0739	heme binding
XcfCFBP6990P_RS15185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP6990P_RS15190	COG1272	protein, Hemolysin III
XcfCFBP6990P_RS15195	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP6990P_RS15200	COG0517	IMP dehydrogenase activity
XcfCFBP6990P_RS15200	COG0516	GMP reductase activity
XcfCFBP6990P_RS15205	COG0463	Glycosyl transferase, family 2
XcfCFBP6990P_RS15210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6990P_RS15215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP6990P_RS15225	COG4771	TonB-dependent receptor
XcfCFBP6990P_RS15235	COG1309	transcriptional regulator
XcfCFBP6990P_RS15245	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6990P_RS15275	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP6990P_RS15280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP6990P_RS15295	COG1742	UPF0060 membrane protein
XcfCFBP6990P_RS15300	COG3956	TIGRFAM MazG family protein
XcfCFBP6990P_RS15305	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP6990P_RS15310	COG0494	nUDIX hydrolase
XcfCFBP6990P_RS15320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP6990P_RS15325	COG0837	glucose binding
XcfCFBP6990P_RS15340	COG3858	chitin binding
XcfCFBP6990P_RS15340	COG1388	LysM domain
XcfCFBP6990P_RS15355	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6990P_RS15370	COG0531	amino acid
XcfCFBP6990P_RS15380	COG1486	melibiose metabolic process
XcfCFBP6990P_RS15390	COG3537	Alpha-1,2-mannosidase
XcfCFBP6990P_RS15435	COG3142	Participates in the control of copper homeostasis
XcfCFBP6990P_RS15440	COG1446	asparaginase
XcfCFBP6990P_RS15465	COG0784	Response regulator, receiver
XcfCFBP6990P_RS15465	COG0643	Histidine kinase
XcfCFBP6990P_RS15465	COG2198	Histidine kinase
XcfCFBP6990P_RS15470	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS15475	COG0835	chemotaxis
XcfCFBP6990P_RS15490	COG0189	ligase activity
XcfCFBP6990P_RS15500	COG1397	ADP-ribosylglycohydrolase
XcfCFBP6990P_RS15510	COG1199	ATP-dependent helicase activity
XcfCFBP6990P_RS15520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6990P_RS15525	COG1442	glycosyl transferase family 8
XcfCFBP6990P_RS15525	COG1216	Glycosyl transferase, family 2
XcfCFBP6990P_RS15545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6990P_RS15555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP6990P_RS15560	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP6990P_RS15565	COG0535	radical SAM domain protein
XcfCFBP6990P_RS15570	COG0535	radical SAM domain protein
XcfCFBP6990P_RS15585	COG0837	glucose binding
XcfCFBP6990P_RS15600	COG1643	Atp-dependent helicase
XcfCFBP6990P_RS15605	COG0783	Belongs to the Dps family
XcfCFBP6990P_RS15610	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP6990P_RS15650	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS15670	COG3920	Histidine kinase
XcfCFBP6990P_RS15675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP6990P_RS15685	COG0602	queuosine metabolic process
XcfCFBP6990P_RS15695	COG2885	chlorophyll binding
XcfCFBP6990P_RS15700	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6990P_RS15710	COG0848	biopolymer transport protein
XcfCFBP6990P_RS15720	COG0824	Thioesterase
XcfCFBP6990P_RS15725	COG2255	four-way junction helicase activity
XcfCFBP6990P_RS15735	COG3158	transport of potassium into the cell
XcfCFBP6990P_RS15740	COG0632	four-way junction helicase activity
XcfCFBP6990P_RS15745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP6990P_RS15750	COG0217	transcriptional regulatory protein
XcfCFBP6990P_RS15765	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP6990P_RS15780	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS15820	COG0488	(ABC) transporter
XcfCFBP6990P_RS15860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6990P_RS15860	COG4651	solute:proton antiporter activity
XcfCFBP6990P_RS15870	COG4772	TonB-dependent receptor
XcfCFBP6990P_RS15880	COG4264	IucA IucC family
XcfCFBP6990P_RS15895	COG0019	diaminopimelate decarboxylase activity
XcfCFBP6990P_RS15920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP6990P_RS15930	COG1492	cobalamin metabolic process
XcfCFBP6990P_RS15940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6990P_RS15965	COG4206	TonB-dependent receptor
XcfCFBP6990P_RS15970	COG0542	response to heat
XcfCFBP6990P_RS15975	COG1116	anion transmembrane transporter activity
XcfCFBP6990P_RS15980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6990P_RS15985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP6990P_RS15990	COG0667	Aldo Keto reductase
XcfCFBP6990P_RS15995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6990P_RS16000	COG4771	TonB-dependent receptor
XcfCFBP6990P_RS16005	COG2827	Endonuclease containing a URI domain
XcfCFBP6990P_RS16045	COG1877	trehalose-phosphatase activity
XcfCFBP6990P_RS16050	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6990P_RS16070	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS16075	COG3011	Protein conserved in bacteria
XcfCFBP6990P_RS16090	COG0564	pseudouridine synthase activity
XcfCFBP6990P_RS16095	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6990P_RS16105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6990P_RS16105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP6990P_RS16120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP6990P_RS16125	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6990P_RS16150	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6990P_RS16165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP6990P_RS16170	COG0237	dephospho-CoA kinase activity
XcfCFBP6990P_RS16200	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6990P_RS16210	COG0189	ligase activity
XcfCFBP6990P_RS16255	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP6990P_RS16260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP6990P_RS16265	COG0471	metal ion transport
XcfCFBP6990P_RS16265	COG3273	potassium ion transport
XcfCFBP6990P_RS16290	COG1970	mechanosensitive ion channel activity
XcfCFBP6990P_RS16300	COG1609	Transcriptional regulator
XcfCFBP6990P_RS16310	COG3250	beta-galactosidase activity
XcfCFBP6990P_RS16315	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6990P_RS16325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6990P_RS16335	COG0308	aminopeptidase N
XcfCFBP6990P_RS16340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS16350	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP6990P_RS16350	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP6990P_RS16355	COG0175	sulfate reduction
XcfCFBP6990P_RS16360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6990P_RS16365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP6990P_RS16370	COG0175	sulfate reduction
XcfCFBP6990P_RS16390	COG2198	Histidine kinase
XcfCFBP6990P_RS16390	COG0784	Response regulator, receiver
XcfCFBP6990P_RS16390	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS16410	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6990P_RS16410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6990P_RS16425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP6990P_RS16430	COG3588	fructose-bisphosphate aldolase
XcfCFBP6990P_RS16445	COG0469	pyruvate kinase activity
XcfCFBP6990P_RS16455	COG0126	phosphoglycerate kinase activity
XcfCFBP6990P_RS16480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP6990P_RS16490	COG3047	cAMP biosynthetic process
XcfCFBP6990P_RS16495	COG3047	cAMP biosynthetic process
XcfCFBP6990P_RS16505	COG3453	Protein conserved in bacteria
XcfCFBP6990P_RS16505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6990P_RS16510	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP6990P_RS16515	COG4149	molybdate abc transporter
XcfCFBP6990P_RS16520	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP6990P_RS16555	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP6990P_RS16560	COG0739	heme binding
XcfCFBP6990P_RS16565	COG4773	Receptor
XcfCFBP6990P_RS16570	COG0596	Alpha beta hydrolase
XcfCFBP6990P_RS16575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP6990P_RS16580	COG1301	dicarboxylic acid transport
XcfCFBP6990P_RS16595	COG2304	oxidoreductase activity
XcfCFBP6990P_RS16615	COG0714	Associated with various cellular activities
XcfCFBP6990P_RS16645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP6990P_RS16670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP6990P_RS16680	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP6990P_RS16695	COG2271	Major facilitator Superfamily
XcfCFBP6990P_RS16710	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS16715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6990P_RS16730	COG1561	YicC-like family, N-terminal region
XcfCFBP6990P_RS16735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP6990P_RS16745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP6990P_RS16750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP6990P_RS16765	COG0006	proline dipeptidase activity
XcfCFBP6990P_RS16775	COG0006	proline dipeptidase activity
XcfCFBP6990P_RS16780	COG3079	Belongs to the UPF0149 family
XcfCFBP6990P_RS16800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP6990P_RS16810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP6990P_RS16820	COG2912	Transglutaminase-like superfamily
XcfCFBP6990P_RS16825	COG1773	rubredoxin
XcfCFBP6990P_RS16830	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP6990P_RS16845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6990P_RS16860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6990P_RS16890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP6990P_RS16895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6990P_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS16910	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6990P_RS16925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6990P_RS16930	COG0563	adenylate kinase activity
XcfCFBP6990P_RS16945	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP6990P_RS16955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP6990P_RS16975	COG3710	Transcriptional regulator
XcfCFBP6990P_RS16980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP6990P_RS16995	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS17000	COG0405	Gamma-glutamyltransferase
XcfCFBP6990P_RS17005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP6990P_RS17025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP6990P_RS17030	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6990P_RS17035	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP6990P_RS17045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP6990P_RS17065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6990P_RS17070	COG1538	Outer membrane efflux protein
XcfCFBP6990P_RS17075	COG1519	Transferase
XcfCFBP6990P_RS17080	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6990P_RS17130	COG0281	malic enzyme
XcfCFBP6990P_RS17130	COG0280	phosphate acetyltransferase
XcfCFBP6990P_RS17135	COG1301	dicarboxylic acid transport
XcfCFBP6990P_RS17160	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS17165	COG0667	Aldo Keto reductase
XcfCFBP6990P_RS17180	COG2197	response regulator
XcfCFBP6990P_RS17190	COG0642	Histidine kinase
XcfCFBP6990P_RS17210	COG2851	Citrate transporter
XcfCFBP6990P_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS17220	COG1609	Transcriptional regulator
XcfCFBP6990P_RS17225	COG2211	Major facilitator Superfamily
XcfCFBP6990P_RS17255	COG1162	GTPase activity
XcfCFBP6990P_RS17290	COG0436	Aminotransferase
XcfCFBP6990P_RS17305	COG0726	polysaccharide deacetylase
XcfCFBP6990P_RS17310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6990P_RS17325	COG3964	amidohydrolase
XcfCFBP6990P_RS17330	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6990P_RS17350	COG1307	EDD domain protein, DegV family
XcfCFBP6990P_RS17355	COG0242	peptide deformylase activity
XcfCFBP6990P_RS17380	COG0457	Tetratricopeptide repeat
XcfCFBP6990P_RS17385	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP6990P_RS17390	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS17395	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS17410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP6990P_RS17465	COG2188	Transcriptional regulator
XcfCFBP6990P_RS17475	COG1450	Type ii and iii secretion system protein
XcfCFBP6990P_RS17490	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP6990P_RS17495	COG3156	type II secretion system protein K
XcfCFBP6990P_RS17500	COG4795	General secretion pathway protein
XcfCFBP6990P_RS17505	COG2165	general secretion pathway protein
XcfCFBP6990P_RS17510	COG4970	Tfp pilus assembly protein FimT
XcfCFBP6990P_RS17515	COG2165	general secretion pathway protein
XcfCFBP6990P_RS17520	COG1459	type II secretion system
XcfCFBP6990P_RS17530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6990P_RS17535	COG1404	Belongs to the peptidase S8 family
XcfCFBP6990P_RS17540	COG5295	Hep Hag repeat protein
XcfCFBP6990P_RS17545	COG1404	Belongs to the peptidase S8 family
XcfCFBP6990P_RS17550	COG5295	Hep Hag repeat protein
XcfCFBP6990P_RS17555	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP6990P_RS17555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP6990P_RS17570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6990P_RS17585	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6990P_RS17600	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP6990P_RS17610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6990P_RS17625	COG0525	valine-tRNA ligase activity
XcfCFBP6990P_RS17660	COG1183	phosphatidylcholine synthase activity
XcfCFBP6990P_RS17670	COG0442	prolyl-tRNA aminoacylation
XcfCFBP6990P_RS17685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6990P_RS17690	COG1127	ABC transporter
XcfCFBP6990P_RS17695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6990P_RS17695	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP6990P_RS17730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6990P_RS17735	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6990P_RS17735	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP6990P_RS17765	COG2086	electron transfer activity
XcfCFBP6990P_RS17780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6990P_RS17780	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6990P_RS17785	COG0277	FAD linked oxidase domain protein
XcfCFBP6990P_RS17800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6990P_RS17830	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6990P_RS17830	COG1216	Glycosyl transferase, family 2
XcfCFBP6990P_RS17850	COG0626	cystathionine gamma-synthase activity
XcfCFBP6990P_RS17880	COG0625	glutathione transferase activity
XcfCFBP6990P_RS17895	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6990P_RS17905	COG4771	TonB-dependent receptor
XcfCFBP6990P_RS17915	COG0720	synthase
XcfCFBP6990P_RS17940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP6990P_RS17945	COG1956	GAF domain-containing protein
XcfCFBP6990P_RS17955	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP6990P_RS17965	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6990P_RS17970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6990P_RS17975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6990P_RS17990	COG0339	signal peptide processing
XcfCFBP6990P_RS18040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6990P_RS18045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS18050	COG1136	(ABC) transporter
XcfCFBP6990P_RS18055	COG0577	efflux transmembrane transporter activity
XcfCFBP6990P_RS18060	COG1136	(ABC) transporter
XcfCFBP6990P_RS18060	COG0577	efflux transmembrane transporter activity
XcfCFBP6990P_RS18075	COG4191	Histidine kinase
XcfCFBP6990P_RS18080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP6990P_RS18100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP6990P_RS18105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP6990P_RS18110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP6990P_RS18115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP6990P_RS18120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP6990P_RS18125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP6990P_RS18135	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP6990P_RS18155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6990P_RS18165	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6990P_RS18205	COG2011	ABC-type metal ion transport system permease component
XcfCFBP6990P_RS18210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP6990P_RS18215	COG0697	spore germination
XcfCFBP6990P_RS18220	COG1666	GTP binding
XcfCFBP6990P_RS18230	COG0784	Response regulator, receiver
XcfCFBP6990P_RS18230	COG5002	protein histidine kinase activity
XcfCFBP6990P_RS18230	COG2198	Histidine kinase
XcfCFBP6990P_RS18260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6990P_RS18265	COG1187	pseudouridine synthase activity
XcfCFBP6990P_RS18270	COG2813	Specifically methylates the guanine in position
XcfCFBP6990P_RS18290	COG2202	Pas domain
XcfCFBP6990P_RS18290	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS18310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP6990P_RS18315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6990P_RS18375	COG0842	Transport permease protein
XcfCFBP6990P_RS18385	COG0025	NhaP-type Na H and K H
XcfCFBP6990P_RS18395	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP6990P_RS18400	COG1573	uracil-dna glycosylase
XcfCFBP6990P_RS18410	COG3384	dioxygenase
XcfCFBP6990P_RS18420	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS18430	COG0667	Aldo Keto reductase
XcfCFBP6990P_RS18445	COG3590	peptidase
XcfCFBP6990P_RS18460	COG0531	amino acid
XcfCFBP6990P_RS18475	COG2972	Histidine kinase
XcfCFBP6990P_RS18495	COG3685	Protein conserved in bacteria
XcfCFBP6990P_RS18500	COG3546	catalase activity
XcfCFBP6990P_RS18535	COG2204	response regulator
XcfCFBP6990P_RS18550	COG1271	oxidase subunit
XcfCFBP6990P_RS18555	COG1294	oxidase, subunit
XcfCFBP6990P_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS18575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP6990P_RS18595	COG1132	(ABC) transporter
XcfCFBP6990P_RS18610	COG1063	alcohol dehydrogenase
XcfCFBP6990P_RS18685	COG0251	oxidation-reduction process
XcfCFBP6990P_RS18700	COG0840	transmembrane signaling receptor activity
XcfCFBP6990P_RS18715	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS18720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6990P_RS18750	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6990P_RS18765	COG0024	Methionine aminopeptidase
XcfCFBP6990P_RS18795	COG1487	ribonuclease activity
XcfCFBP6990P_RS18870	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6990P_RS18935	COG1196	nuclear chromosome segregation
XcfCFBP6990P_RS18965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6990P_RS18970	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP6990P_RS18975	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6990P_RS19030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6990P_RS19030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP6990P_RS19035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP6990P_RS19040	COG0242	peptide deformylase activity
XcfCFBP6990P_RS19045	COG1652	LysM domain
XcfCFBP6990P_RS19050	COG0758	DNA mediated transformation
XcfCFBP6990P_RS19070	COG1754	DNA topoisomerase type I activity
XcfCFBP6990P_RS19070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6990P_RS19075	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP6990P_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS19105	COG0616	signal peptide processing
XcfCFBP6990P_RS19110	COG0534	Mate efflux family protein
XcfCFBP6990P_RS19130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcfCFBP6990P_RS19135	COG0625	glutathione transferase activity
XcfCFBP6990P_RS19150	COG1252	NADH dehydrogenase
XcfCFBP6990P_RS19155	COG2860	membrane
XcfCFBP6990P_RS19160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6990P_RS19165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP6990P_RS19170	COG3437	response regulator, receiver
XcfCFBP6990P_RS19175	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP6990P_RS19180	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP6990P_RS19185	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6990P_RS19190	COG3118	belongs to the thioredoxin family
XcfCFBP6990P_RS19195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP6990P_RS19200	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcfCFBP6990P_RS19205	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS19225	COG1652	LysM domain
XcfCFBP6990P_RS19230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6990P_RS19230	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6990P_RS19235	COG1473	amidohydrolase
XcfCFBP6990P_RS19240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS19245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6990P_RS19265	COG5383	Protein conserved in bacteria
XcfCFBP6990P_RS19320	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6990P_RS19330	COG0531	amino acid
XcfCFBP6990P_RS19345	COG4682	membrane
XcfCFBP6990P_RS19350	COG2133	pyrroloquinoline quinone binding
XcfCFBP6990P_RS19360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP6990P_RS19365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP6990P_RS19375	COG1610	YqeY-like protein
XcfCFBP6990P_RS19385	COG1295	ribonuclease BN
XcfCFBP6990P_RS19390	COG0358	DNA primase activity
XcfCFBP6990P_RS19405	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP6990P_RS19435	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP6990P_RS19450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP6990P_RS19495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP6990P_RS19500	COG0739	heme binding
XcfCFBP6990P_RS19505	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP6990P_RS19515	COG2223	nitrite transmembrane transporter activity
XcfCFBP6990P_RS19520	COG0708	Exodeoxyribonuclease III
XcfCFBP6990P_RS19525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP6990P_RS19535	COG1192	Involved in chromosome partitioning
XcfCFBP6990P_RS19540	COG1475	DNA binding
XcfCFBP6990P_RS19560	COG0463	Glycosyl transferase, family 2
XcfCFBP6990P_RS19580	COG0756	dUTP diphosphatase activity
XcfCFBP6990P_RS19585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP6990P_RS19590	COG2003	Belongs to the UPF0758 family
XcfCFBP6990P_RS19595	COG0018	arginyl-trna synthetase
XcfCFBP6990P_RS19610	COG4221	oxidoreductase activity
XcfCFBP6990P_RS19615	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6990P_RS19615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP6990P_RS19625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6990P_RS19635	COG1166	arginine decarboxylase activity
XcfCFBP6990P_RS19640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP6990P_RS19665	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6990P_RS19665	COG3291	Pkd domain containing protein
XcfCFBP6990P_RS19685	COG0606	chelatase, subunit chli
XcfCFBP6990P_RS19700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP6990P_RS19735	COG1690	Belongs to the RtcB family
XcfCFBP6990P_RS19770	COG1090	epimerase
XcfCFBP6990P_RS19780	COG0642	Histidine kinase
XcfCFBP6990P_RS19805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6990P_RS19835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6990P_RS19850	COG0753	catalase activity
XcfCFBP6990P_RS19865	COG2197	response regulator
XcfCFBP6990P_RS19870	COG4585	Histidine kinase
XcfCFBP6990P_RS19875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS19880	COG1136	(ABC) transporter
XcfCFBP6990P_RS19905	COG0697	spore germination
XcfCFBP6990P_RS19925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6990P_RS19930	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP6990P_RS19935	COG3237	CsbD-like
XcfCFBP6990P_RS19975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP6990P_RS19990	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP6990P_RS20040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6990P_RS20070	COG1199	ATP-dependent helicase activity
XcfCFBP6990P_RS20085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP6990P_RS20160	COG0625	glutathione transferase activity
XcfCFBP6990P_RS20195	COG4555	ABC transporter
XcfCFBP6990P_RS20205	COG1476	TRANSCRIPTIONal
XcfCFBP6990P_RS20225	COG1230	cation diffusion facilitator family transporter
XcfCFBP6990P_RS20235	COG4774	siderophore transport
XcfCFBP6990P_RS20250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6990P_RS20255	COG1131	(ABC) transporter
XcfCFBP6990P_RS20260	COG0842	Transport permease protein
XcfCFBP6990P_RS20265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP6990P_RS20285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6990P_RS20295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6990P_RS20305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6990P_RS20320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcfCFBP6990P_RS20320	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6990P_RS20320	COG1042	CoA-binding domain protein
XcfCFBP6990P_RS20325	COG2239	Acts as a magnesium transporter
XcfCFBP6990P_RS20345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6990P_RS20350	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6990P_RS20365	COG3100	YcgL domain-containing protein
XcfCFBP6990P_RS20370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6990P_RS20380	COG0463	Glycosyl transferase, family 2
XcfCFBP6990P_RS20400	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS20440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6990P_RS20455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6990P_RS20485	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6990P_RS20485	COG1506	peptidase
XcfCFBP6990P_RS20485	COG4946	Tricorn protease homolog
XcfCFBP6990P_RS20505	COG0408	coproporphyrinogen oxidase activity
XcfCFBP6990P_RS20540	COG0515	serine threonine protein kinase
XcfCFBP6990P_RS20545	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6990P_RS20720	COG0210	DNA helicase
XcfCFBP6990P_RS20730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6990P_RS20735	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS20740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6990P_RS20755	COG2159	amidohydrolase
XcfCFBP6990P_RS20785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6990P_RS20805	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP6990P_RS20810	COG3540	Alkaline phosphatase
XcfCFBP6990P_RS20820	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP6990P_RS20835	COG0708	Exodeoxyribonuclease III
XcfCFBP6990P_RS20840	COG1940	carbohydrate kinase activity
XcfCFBP6990P_RS20840	COG1846	Transcriptional regulator
XcfCFBP6990P_RS20850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6990P_RS20865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP6990P_RS20870	COG3162	membrane
XcfCFBP6990P_RS20880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP6990P_RS20910	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6990P_RS20930	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS20935	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP6990P_RS20940	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6990P_RS20945	COG3254	rhamnose metabolic process
XcfCFBP6990P_RS20950	COG0738	Major facilitator superfamily
XcfCFBP6990P_RS20955	COG1414	Transcriptional regulator
XcfCFBP6990P_RS20960	COG1971	Probably functions as a manganese efflux pump
XcfCFBP6990P_RS20965	COG2205	protein histidine kinase activity
XcfCFBP6990P_RS20980	COG3459	Glycosyltransferase 36 associated
XcfCFBP6990P_RS20985	COG2211	Major facilitator Superfamily
XcfCFBP6990P_RS20990	COG3265	gluconokinase activity
XcfCFBP6990P_RS21000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6990P_RS21020	COG2911	Protein conserved in bacteria
XcfCFBP6990P_RS21025	COG0729	surface antigen
XcfCFBP6990P_RS21035	COG3328	transposase activity
XcfCFBP6990P_RS21065	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP6990P_RS21070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6990P_RS21090	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6990P_RS21090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6990P_RS21100	COG0805	protein transport
XcfCFBP6990P_RS21105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6990P_RS21110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6990P_RS21120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP6990P_RS21140	COG2974	May be involved in recombination
XcfCFBP6990P_RS21145	COG0037	tRNA processing
XcfCFBP6990P_RS21150	COG2115	Belongs to the xylose isomerase family
XcfCFBP6990P_RS21160	COG3661	Belongs to the glycosyl hydrolase 67 family
XcfCFBP6990P_RS21170	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6990P_RS21180	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6990P_RS21185	COG0246	Mannitol dehydrogenase
XcfCFBP6990P_RS21235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6990P_RS21265	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6990P_RS21275	COG3250	beta-galactosidase activity
XcfCFBP6990P_RS21280	COG1904	glucuronate isomerase
XcfCFBP6990P_RS21295	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6990P_RS21310	COG2211	Major facilitator Superfamily
XcfCFBP6990P_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS21365	COG0604	alcohol dehydrogenase
XcfCFBP6990P_RS21365	COG3321	synthase
XcfCFBP6990P_RS21370	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP6990P_RS21405	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP6990P_RS21410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP6990P_RS21420	COG3132	Protein of unknown function, DUF480
XcfCFBP6990P_RS21435	COG0210	DNA helicase
XcfCFBP6990P_RS21440	COG1435	thymidine kinase activity
XcfCFBP6990P_RS21450	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP6990P_RS21460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP6990P_RS21490	COG3135	benzoate transporter
XcfCFBP6990P_RS21515	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP6990P_RS21525	COG3012	SEC-C Motif Domain Protein
XcfCFBP6990P_RS21530	COG0730	response to heat
XcfCFBP6990P_RS21555	COG0302	gtp cyclohydrolase
XcfCFBP6990P_RS21570	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6990P_RS21580	COG1289	transmembrane transporter activity
XcfCFBP6990P_RS21585	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS21595	COG0583	DNA-binding transcription factor activity
XcfCFBP6990P_RS21600	COG4221	oxidoreductase activity
XcfCFBP6990P_RS21610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6990P_RS21670	COG0564	pseudouridine synthase activity
XcfCFBP6990P_RS21710	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS21755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP6990P_RS21760	COG1074	ATP-dependent DNA helicase activity
XcfCFBP6990P_RS21765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP6990P_RS21800	COG1127	ABC transporter
XcfCFBP6990P_RS21805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6990P_RS21810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6990P_RS21825	COG2853	Lipoprotein
XcfCFBP6990P_RS21835	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6990P_RS21845	COG1322	Protein conserved in bacteria
XcfCFBP6990P_RS21860	COG0625	glutathione transferase activity
XcfCFBP6990P_RS21870	COG0531	amino acid
XcfCFBP6990P_RS21875	COG3537	Alpha-1,2-mannosidase
XcfCFBP6990P_RS21890	COG3706	GGDEF domain
XcfCFBP6990P_RS21895	COG3835	regulator
XcfCFBP6990P_RS21920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6990P_RS21930	COG0861	Integral membrane protein TerC family
XcfCFBP6990P_RS21940	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP6990P_RS21955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP6990P_RS21970	COG0706	membrane insertase activity
XcfCFBP6990P_RS21975	COG0594	ribonuclease P activity
XcfCFBP6990P_RS21990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcfCFBP6990P_RS22000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6990P_RS22005	COG0187	DNA topoisomerase II activity
XcfCFBP6990P_RS22015	COG0501	Belongs to the peptidase M48B family
XcfCFBP6990P_RS22050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP6990P_RS22060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6990P_RS22110	COG0793	Belongs to the peptidase S41A family
XcfCFBP6990P_RS22115	COG4942	peptidase
XcfCFBP6990P_RS22125	COG2234	aminopeptidase activity
XcfCFBP6990P_RS22135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6990P_RS22140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6990P_RS22145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6990P_RS22155	COG1064	alcohol dehydrogenase
XcfCFBP6990P_RS22170	COG0493	'glutamate synthase
XcfCFBP6990P_RS22175	COG0069	glutamate synthase activity
XcfCFBP6990P_RS22175	COG0067	glutamate synthase
XcfCFBP6990P_RS22175	COG0070	glutamate synthase
XcfCFBP6990P_RS22265	COG1111	helicase
XcfCFBP6990P_RS22265	COG1205	dead DEAH box helicase
XcfCFBP6990P_RS22270	COG1272	protein, Hemolysin III
XcfCFBP6990P_RS22290	COG0300	oxidoreductase activity
XcfCFBP6990P_RS22295	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS22320	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP6990P_RS22350	COG3237	CsbD-like
XcfCFBP6990P_RS22400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6990P_RS22410	COG0477	Major facilitator Superfamily
XcfCFBP6990P_RS22455	COG0714	Associated with various cellular activities
XcfCFBP6990P_RS22500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP6990P_RS22510	COG4772	TonB-dependent receptor
XcfCFBP6990P_RS22525	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6990P_RS22550	COG1304	FMN binding
XcfCFBP6990P_RS22565	COG4585	Histidine kinase
XcfCFBP6990P_RS22570	COG2197	response regulator
XcfCFBP6990P_RS22590	COG3710	Transcriptional regulator
XcfCFBP6990P_RS22595	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP6990P_RS22740	COG0366	Alpha amylase catalytic
XcfCFBP6990P_RS22745	COG0366	Alpha amylase catalytic
XcfCFBP6990P_RS22750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6990P_RS22770	COG0657	acetylesterase activity
XcfCFBP6990P_RS22770	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6990P_RS22780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP6990P_RS22795	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6990P_RS22800	COG1609	Transcriptional regulator
XcfCFBP6990P_RS22810	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP6990P_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6990P_RS22825	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6990P_RS22835	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP6990P_RS22840	COG1522	sequence-specific DNA binding
XcfCFBP6990P_RS22850	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP6990P_RS22860	COG1119	ATPase activity
XcfCFBP6990P_RS22875	COG1125	glycine betaine transport
XcfCFBP6990P_RS22890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6990P_RS22920	COG0489	protein tyrosine kinase activity
XcfCFBP6990P_RS22925	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP6990P_RS22935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6990P_RS22980	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP6990P_RS22990	COG0174	glutamine synthetase
XcfCFBP6990P_RS22995	COG0347	Belongs to the P(II) protein family
XcfCFBP6990P_RS23000	COG0004	ammonium transporteR
XcfCFBP6990P_RS23005	COG3852	Histidine kinase
XcfCFBP6990P_RS23010	COG2204	response regulator
XcfCFBP6990P_RS23015	COG2032	superoxide dismutase activity
XcfCFBP6990P_RS23020	COG2032	superoxide dismutase activity
XcfCFBP6990P_RS23025	COG0346	lactoylglutathione lyase activity
XcfCFBP6990P_RS23085	COG4962	Type ii secretion system protein e
XcfCFBP6990P_RS23100	COG3451	type IV secretory pathway VirB4
XcfCFBP6990P_RS23110	COG3846	protein secretion by the type IV secretion system
XcfCFBP6990P_RS23180	COG1487	ribonuclease activity
XcfCFBP6990P_RS23185	COG4691	Plasmid stability protein
XcfCFBP6990P_RS23190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP6990P_RS23380	COG3328	transposase activity
XcfCFBP6990P_RS23405	COG4962	Type ii secretion system protein e
XcfCFBP6990P_RS23420	COG3451	type IV secretory pathway VirB4
XcfCFBP6990P_RS23430	COG3846	protein secretion by the type IV secretion system