locus-tag	class	description
XcfCFBP6996P_RS00010	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6996P_RS00020	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6996P_RS00025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6996P_RS00030	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6996P_RS00035	COG1764	response to oxidative stress
XcfCFBP6996P_RS00045	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6996P_RS00055	COG0527	aspartate kinase activity
XcfCFBP6996P_RS00070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP6996P_RS00085	COG0142	geranyltranstransferase activity
XcfCFBP6996P_RS00090	COG0629	single-stranded DNA binding
XcfCFBP6996P_RS00095	COG2203	Gaf domain
XcfCFBP6996P_RS00095	COG3706	GGDEF domain
XcfCFBP6996P_RS00095	COG4251	negative regulation of phosphorylation
XcfCFBP6996P_RS00095	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS00100	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS00100	COG3321	synthase
XcfCFBP6996P_RS00100	COG0604	alcohol dehydrogenase
XcfCFBP6996P_RS00105	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6996P_RS00110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6996P_RS00115	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6996P_RS00120	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP6996P_RS00170	COG2879	small protein
XcfCFBP6996P_RS00175	COG1966	Carbon starvation protein
XcfCFBP6996P_RS00180	COG1741	Belongs to the pirin family
XcfCFBP6996P_RS00195	COG1741	Belongs to the pirin family
XcfCFBP6996P_RS00205	COG1515	deoxyribonuclease V activity
XcfCFBP6996P_RS00210	COG0588	phosphoglycerate mutase activity
XcfCFBP6996P_RS00220	COG3590	peptidase
XcfCFBP6996P_RS00225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS00235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6996P_RS00245	COG0835	chemotaxis
XcfCFBP6996P_RS00250	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS00255	COG0643	Histidine kinase
XcfCFBP6996P_RS00255	COG2198	Histidine kinase
XcfCFBP6996P_RS00265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP6996P_RS00275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP6996P_RS00280	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS00295	COG4452	Inner membrane protein CreD
XcfCFBP6996P_RS00320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6996P_RS00325	COG0735	belongs to the Fur family
XcfCFBP6996P_RS00340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6996P_RS00350	COG1309	transcriptional regulator
XcfCFBP6996P_RS00360	COG2207	Transcriptional regulator
XcfCFBP6996P_RS00370	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS00375	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS00380	COG0667	Aldo Keto reductase
XcfCFBP6996P_RS00485	COG1595	DNA-templated transcription, initiation
XcfCFBP6996P_RS00495	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS00495	COG5002	protein histidine kinase activity
XcfCFBP6996P_RS00500	COG1187	pseudouridine synthase activity
XcfCFBP6996P_RS00520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6996P_RS00530	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6996P_RS00535	COG5000	phosphorelay sensor kinase activity
XcfCFBP6996P_RS00535	COG5002	protein histidine kinase activity
XcfCFBP6996P_RS00540	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS00545	COG1538	Outer membrane efflux protein
XcfCFBP6996P_RS00570	COG1132	(ABC) transporter
XcfCFBP6996P_RS00615	COG2155	Conserved Protein
XcfCFBP6996P_RS00650	COG3118	belongs to the thioredoxin family
XcfCFBP6996P_RS00660	COG0495	leucyl-tRNA aminoacylation
XcfCFBP6996P_RS00675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP6996P_RS00690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP6996P_RS00705	COG2968	Membrane
XcfCFBP6996P_RS00710	COG0424	maF-like protein
XcfCFBP6996P_RS00720	COG3164	Protein of unknown function
XcfCFBP6996P_RS00730	COG0312	modulator of DNA gyrase
XcfCFBP6996P_RS00735	COG3028	Belongs to the UPF0307 family
XcfCFBP6996P_RS00740	COG0312	modulator of DNA gyrase
XcfCFBP6996P_RS00750	COG4104	PAAR repeat-containing protein
XcfCFBP6996P_RS00755	COG0142	geranyltranstransferase activity
XcfCFBP6996P_RS00760	COG1722	exodeoxyribonuclease VII activity
XcfCFBP6996P_RS00765	COG0037	tRNA processing
XcfCFBP6996P_RS00775	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP6996P_RS00780	COG1301	dicarboxylic acid transport
XcfCFBP6996P_RS00785	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6996P_RS00795	COG0791	NLP P60 protein
XcfCFBP6996P_RS00800	COG0791	NLP P60 protein
XcfCFBP6996P_RS00805	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6996P_RS00810	COG2311	Membrane
XcfCFBP6996P_RS00815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6996P_RS00820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6996P_RS00840	COG3590	peptidase
XcfCFBP6996P_RS00845	COG3590	peptidase
XcfCFBP6996P_RS00870	COG0489	protein tyrosine kinase activity
XcfCFBP6996P_RS00880	COG0717	Belongs to the dCTP deaminase family
XcfCFBP6996P_RS00905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6996P_RS00925	COG0494	nUDIX hydrolase
XcfCFBP6996P_RS00930	COG0433	COG0433 Predicted ATPase
XcfCFBP6996P_RS00945	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP6996P_RS00955	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6996P_RS00960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP6996P_RS00965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP6996P_RS00970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP6996P_RS00985	COG0101	tRNA pseudouridine synthase activity
XcfCFBP6996P_RS00990	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP6996P_RS01000	COG0133	tryptophan synthase activity
XcfCFBP6996P_RS01010	COG0159	tryptophan synthase activity
XcfCFBP6996P_RS01015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP6996P_RS01020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6996P_RS01050	COG4221	oxidoreductase activity
XcfCFBP6996P_RS01055	COG0149	triose-phosphate isomerase activity
XcfCFBP6996P_RS01070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6996P_RS01075	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6996P_RS01080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6996P_RS01085	COG0649	NAD binding
XcfCFBP6996P_RS01090	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP6996P_RS01095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP6996P_RS01105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP6996P_RS01110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6996P_RS01135	COG1007	ATP synthesis coupled electron transport
XcfCFBP6996P_RS01145	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP6996P_RS01150	COG0195	Participates in both transcription termination and antitermination
XcfCFBP6996P_RS01155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP6996P_RS01160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP6996P_RS01165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP6996P_RS01170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP6996P_RS01175	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP6996P_RS01210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6996P_RS01220	COG2095	MarC family integral membrane protein
XcfCFBP6996P_RS01235	COG1611	Belongs to the LOG family
XcfCFBP6996P_RS01240	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6996P_RS01275	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6996P_RS01280	COG0556	nucleotide-excision repair
XcfCFBP6996P_RS01295	COG3505	Type IV secretory pathway VirD4
XcfCFBP6996P_RS01315	COG2948	multi-organism process
XcfCFBP6996P_RS01335	COG3702	type iv secretory pathway
XcfCFBP6996P_RS01405	COG3328	transposase activity
XcfCFBP6996P_RS01450	COG0366	Alpha amylase catalytic
XcfCFBP6996P_RS01465	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6996P_RS01475	COG2211	Major facilitator Superfamily
XcfCFBP6996P_RS01475	COG2190	(PTS) system
XcfCFBP6996P_RS01490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP6996P_RS01495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP6996P_RS01510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP6996P_RS01515	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP6996P_RS01515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6996P_RS01570	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS01580	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS01605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6996P_RS01610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6996P_RS01615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6996P_RS01635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP6996P_RS01645	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS01655	COG3040	lipid binding
XcfCFBP6996P_RS01670	COG0322	excinuclease ABC activity
XcfCFBP6996P_RS01685	COG4191	Histidine kinase
XcfCFBP6996P_RS01685	COG0784	Response regulator, receiver
XcfCFBP6996P_RS01690	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP6996P_RS01695	COG1194	a g-specific adenine glycosylase
XcfCFBP6996P_RS01700	COG0552	protein localization to endoplasmic reticulum
XcfCFBP6996P_RS01710	COG3938	Belongs to the proline racemase family
XcfCFBP6996P_RS01715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6996P_RS01730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6996P_RS01740	COG0006	proline dipeptidase activity
XcfCFBP6996P_RS01755	COG0531	amino acid
XcfCFBP6996P_RS01845	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6996P_RS01850	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP6996P_RS01855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP6996P_RS01870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP6996P_RS01875	COG0405	Gamma-glutamyltransferase
XcfCFBP6996P_RS01880	COG3291	Pkd domain containing protein
XcfCFBP6996P_RS01885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP6996P_RS01920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP6996P_RS01925	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP6996P_RS01930	COG1862	Preprotein translocase
XcfCFBP6996P_RS01940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP6996P_RS01950	COG3328	transposase activity
XcfCFBP6996P_RS01975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6996P_RS01975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6996P_RS01980	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP6996P_RS01985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6996P_RS01985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6996P_RS01990	COG1609	Transcriptional regulator
XcfCFBP6996P_RS01995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6996P_RS02000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS02010	COG2902	Dehydrogenase
XcfCFBP6996P_RS02045	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS02065	COG5002	protein histidine kinase activity
XcfCFBP6996P_RS02065	COG0784	Response regulator, receiver
XcfCFBP6996P_RS02065	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS02070	COG2733	membrane
XcfCFBP6996P_RS02080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP6996P_RS02095	COG2223	nitrite transmembrane transporter activity
XcfCFBP6996P_RS02100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP6996P_RS02105	COG0243	molybdopterin cofactor binding
XcfCFBP6996P_RS02115	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS02120	COG2703	oxygen carrier activity
XcfCFBP6996P_RS02130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6996P_RS02135	COG0174	glutamine synthetase
XcfCFBP6996P_RS02140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcfCFBP6996P_RS02155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP6996P_RS02175	COG3842	ATPase activity
XcfCFBP6996P_RS02185	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP6996P_RS02190	COG1177	transmembrane transport
XcfCFBP6996P_RS02195	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6996P_RS02210	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP6996P_RS02220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP6996P_RS02230	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP6996P_RS02235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6996P_RS02250	COG0741	lytic transglycosylase activity
XcfCFBP6996P_RS02260	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6996P_RS02265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP6996P_RS02270	COG2857	Cytochrome c1
XcfCFBP6996P_RS02275	COG0625	glutathione transferase activity
XcfCFBP6996P_RS02280	COG2969	positive regulation of protein catabolic process
XcfCFBP6996P_RS02305	COG1201	RNA secondary structure unwinding
XcfCFBP6996P_RS02310	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP6996P_RS02315	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS02320	COG0835	chemotaxis
XcfCFBP6996P_RS02365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6996P_RS02380	COG1570	exodeoxyribonuclease VII activity
XcfCFBP6996P_RS02385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6996P_RS02390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6996P_RS02390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP6996P_RS02395	COG0802	atpase or kinase
XcfCFBP6996P_RS02400	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6996P_RS02405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP6996P_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS02435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6996P_RS02440	COG0501	Belongs to the peptidase M48B family
XcfCFBP6996P_RS02450	COG2081	HI0933 family
XcfCFBP6996P_RS02455	COG4681	YaeQ
XcfCFBP6996P_RS02465	COG0625	glutathione transferase activity
XcfCFBP6996P_RS02475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP6996P_RS02480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP6996P_RS02485	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6996P_RS02490	COG0488	(ABC) transporter
XcfCFBP6996P_RS02510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP6996P_RS02515	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP6996P_RS02530	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS02530	COG3300	MHYT domain
XcfCFBP6996P_RS02535	COG1509	lysine 2,3-aminomutase activity
XcfCFBP6996P_RS02540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6996P_RS02550	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6996P_RS02555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP6996P_RS02605	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP6996P_RS02625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP6996P_RS02630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP6996P_RS02645	COG2166	iron-sulfur cluster assembly
XcfCFBP6996P_RS02650	COG0215	cysteine-tRNA ligase activity
XcfCFBP6996P_RS02660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP6996P_RS02665	COG0137	argininosuccinate synthase activity
XcfCFBP6996P_RS02675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6996P_RS02680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP6996P_RS02690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP6996P_RS02695	COG0165	Argininosuccinate lyase
XcfCFBP6996P_RS02705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP6996P_RS02710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP6996P_RS02740	COG1294	oxidase, subunit
XcfCFBP6996P_RS02750	COG4988	ABC transporter
XcfCFBP6996P_RS02755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP6996P_RS02760	COG1278	Cold shock
XcfCFBP6996P_RS02765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6996P_RS02785	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP6996P_RS02790	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6996P_RS02810	COG4133	protoheme IX ABC transporter activity
XcfCFBP6996P_RS02815	COG0436	Aminotransferase
XcfCFBP6996P_RS02840	COG1187	pseudouridine synthase activity
XcfCFBP6996P_RS02845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP6996P_RS02850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP6996P_RS02855	COG2350	Protein conserved in bacteria
XcfCFBP6996P_RS02885	COG1175	transmembrane transport
XcfCFBP6996P_RS02890	COG0395	ABC-type sugar transport system, permease component
XcfCFBP6996P_RS02915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6996P_RS02920	COG2957	Belongs to the agmatine deiminase family
XcfCFBP6996P_RS02940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP6996P_RS02945	COG0539	negative regulation of cytoplasmic translation
XcfCFBP6996P_RS02950	COG0776	regulation of translation
XcfCFBP6996P_RS02960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP6996P_RS02965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6996P_RS02975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP6996P_RS02980	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6996P_RS02980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6996P_RS02995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP6996P_RS03005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6996P_RS03005	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6996P_RS03010	COG3002	Belongs to the UPF0753 family
XcfCFBP6996P_RS03015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6996P_RS03020	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS03035	COG2197	response regulator
XcfCFBP6996P_RS03050	COG1335	isochorismatase
XcfCFBP6996P_RS03065	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS03080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6996P_RS03080	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6996P_RS03100	COG3685	Protein conserved in bacteria
XcfCFBP6996P_RS03120	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS03130	COG4566	intracellular signal transduction
XcfCFBP6996P_RS03170	COG3275	phosphorelay sensor kinase activity
XcfCFBP6996P_RS03175	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6996P_RS03205	COG1238	metal cluster binding
XcfCFBP6996P_RS03215	COG3920	Histidine kinase
XcfCFBP6996P_RS03240	COG3220	belongs to the UPF0276 family
XcfCFBP6996P_RS03275	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS03325	COG3321	synthase
XcfCFBP6996P_RS03325	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6996P_RS03325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6996P_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6996P_RS03345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03345	COG3321	synthase
XcfCFBP6996P_RS03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6996P_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03350	COG3321	synthase
XcfCFBP6996P_RS03350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03350	COG3321	synthase
XcfCFBP6996P_RS03350	COG4221	oxidoreductase activity
XcfCFBP6996P_RS03350	COG4221	oxidoreductase activity
XcfCFBP6996P_RS03355	COG3321	synthase
XcfCFBP6996P_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6996P_RS03355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6996P_RS03360	COG4221	oxidoreductase activity
XcfCFBP6996P_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6996P_RS03360	COG3321	synthase
XcfCFBP6996P_RS03365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6996P_RS03370	COG1136	(ABC) transporter
XcfCFBP6996P_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03395	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6996P_RS03400	COG2226	methyltransferase
XcfCFBP6996P_RS03400	COG1073	alpha beta
XcfCFBP6996P_RS03450	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP6996P_RS03450	COG0316	Belongs to the HesB IscA family
XcfCFBP6996P_RS03455	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP6996P_RS03465	COG0428	transporter
XcfCFBP6996P_RS03470	COG3064	Membrane
XcfCFBP6996P_RS03480	COG1530	ribonuclease E activity
XcfCFBP6996P_RS03490	COG1054	Belongs to the UPF0176 family
XcfCFBP6996P_RS03510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP6996P_RS03535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6996P_RS03540	COG0322	excinuclease ABC activity
XcfCFBP6996P_RS03550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP6996P_RS03555	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP6996P_RS03560	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP6996P_RS03565	COG1132	(ABC) transporter
XcfCFBP6996P_RS03570	COG0848	biopolymer transport protein
XcfCFBP6996P_RS03575	COG0811	peptide transport
XcfCFBP6996P_RS03590	COG1136	(ABC) transporter
XcfCFBP6996P_RS03595	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP6996P_RS03605	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP6996P_RS03610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP6996P_RS03625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP6996P_RS03640	COG0354	folic acid binding
XcfCFBP6996P_RS03650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6996P_RS03655	COG0837	glucose binding
XcfCFBP6996P_RS03660	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP6996P_RS03665	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6996P_RS03670	COG0800	Aldolase
XcfCFBP6996P_RS03735	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS03735	COG0784	Response regulator, receiver
XcfCFBP6996P_RS03740	COG2183	response to ionizing radiation
XcfCFBP6996P_RS03750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6996P_RS03750	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6996P_RS03765	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP6996P_RS03775	COG1183	phosphatidylcholine synthase activity
XcfCFBP6996P_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS03795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP6996P_RS03805	COG0668	transmembrane transport
XcfCFBP6996P_RS03825	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP6996P_RS03855	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP6996P_RS03860	COG0303	'Molybdopterin
XcfCFBP6996P_RS03870	COG0708	Exodeoxyribonuclease III
XcfCFBP6996P_RS03910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP6996P_RS03915	COG0303	'Molybdopterin
XcfCFBP6996P_RS03920	COG1160	GTP binding
XcfCFBP6996P_RS03925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6996P_RS03935	COG1426	Protein conserved in bacteria
XcfCFBP6996P_RS03945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP6996P_RS03960	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS03960	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6996P_RS03965	COG0183	Belongs to the thiolase family
XcfCFBP6996P_RS03975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP6996P_RS03980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP6996P_RS03990	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP6996P_RS04000	COG1674	ftsk spoiiie
XcfCFBP6996P_RS04005	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6996P_RS04015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP6996P_RS04040	COG0482	sulfurtransferase activity
XcfCFBP6996P_RS04045	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP6996P_RS04075	COG5002	protein histidine kinase activity
XcfCFBP6996P_RS04095	COG0784	Response regulator, receiver
XcfCFBP6996P_RS04095	COG0835	chemotaxis
XcfCFBP6996P_RS04105	COG1558	bacterial-type flagellum-dependent cell motility
XcfCFBP6996P_RS04110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcfCFBP6996P_RS04120	COG4787	bacterial-type flagellum-dependent cell motility
XcfCFBP6996P_RS04130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcfCFBP6996P_RS04135	COG1706	bacterial-type flagellum-dependent cell motility
XcfCFBP6996P_RS04140	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6996P_RS04140	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6996P_RS04150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcfCFBP6996P_RS04160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcfCFBP6996P_RS04190	COG2201	protein-glutamate methylesterase activity
XcfCFBP6996P_RS04210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6996P_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS04255	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP6996P_RS04305	COG3190	flagellar
XcfCFBP6996P_RS04330	COG1684	flagellar biosynthetic protein fliR
XcfCFBP6996P_RS04390	COG0784	Response regulator, receiver
XcfCFBP6996P_RS04390	COG0643	Histidine kinase
XcfCFBP6996P_RS04390	COG2198	Histidine kinase
XcfCFBP6996P_RS04450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6996P_RS04475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP6996P_RS04480	COG1360	Flagellar Motor Protein
XcfCFBP6996P_RS04490	COG0835	chemotaxis
XcfCFBP6996P_RS04500	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS04510	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04525	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04540	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04545	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04550	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04555	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04565	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04570	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04575	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04580	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04590	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04610	COG0835	chemotaxis
XcfCFBP6996P_RS04620	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS04630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP6996P_RS04635	COG2201	protein-glutamate methylesterase activity
XcfCFBP6996P_RS04645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6996P_RS04675	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6996P_RS04680	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS04685	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS04685	COG2198	Histidine kinase
XcfCFBP6996P_RS04685	COG0784	Response regulator, receiver
XcfCFBP6996P_RS04690	COG2198	Histidine kinase
XcfCFBP6996P_RS04690	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS04690	COG0784	Response regulator, receiver
XcfCFBP6996P_RS04700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP6996P_RS04710	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6996P_RS04720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP6996P_RS04730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6996P_RS04735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP6996P_RS04745	COG0505	Belongs to the CarA family
XcfCFBP6996P_RS04750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP6996P_RS04755	COG2258	MOSC domain
XcfCFBP6996P_RS04760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6996P_RS04805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6996P_RS04825	COG0277	FAD linked oxidase domain protein
XcfCFBP6996P_RS04830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP6996P_RS04840	COG0531	amino acid
XcfCFBP6996P_RS04845	COG0531	amino acid
XcfCFBP6996P_RS04850	COG0235	Class ii aldolase
XcfCFBP6996P_RS04855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP6996P_RS04860	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP6996P_RS04875	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP6996P_RS04875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP6996P_RS04880	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP6996P_RS04885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP6996P_RS04890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP6996P_RS04895	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP6996P_RS04895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP6996P_RS04900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6996P_RS04905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP6996P_RS04910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP6996P_RS04920	COG0124	histidyl-tRNA synthetase
XcfCFBP6996P_RS04925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6996P_RS05015	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP6996P_RS05015	COG0726	polysaccharide deacetylase
XcfCFBP6996P_RS05020	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS05045	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6996P_RS05060	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP6996P_RS05065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP6996P_RS05070	COG0697	spore germination
XcfCFBP6996P_RS05080	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP6996P_RS05090	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6996P_RS05095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP6996P_RS05105	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP6996P_RS05110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6996P_RS05115	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS05115	COG2203	Gaf domain
XcfCFBP6996P_RS05115	COG3706	GGDEF domain
XcfCFBP6996P_RS05115	COG4251	negative regulation of phosphorylation
XcfCFBP6996P_RS05130	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6996P_RS05155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP6996P_RS05160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP6996P_RS05165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP6996P_RS05185	COG1469	GTP cyclohydrolase I activity
XcfCFBP6996P_RS05190	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6996P_RS05205	COG3328	transposase activity
XcfCFBP6996P_RS05210	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS05215	COG2115	Belongs to the xylose isomerase family
XcfCFBP6996P_RS05220	COG1070	Carbohydrate kinase
XcfCFBP6996P_RS05230	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP6996P_RS05270	COG0800	Aldolase
XcfCFBP6996P_RS05275	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6996P_RS05285	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP6996P_RS05290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP6996P_RS05300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6996P_RS05315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP6996P_RS05320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP6996P_RS05335	COG0351	phosphomethylpyrimidine kinase
XcfCFBP6996P_RS05360	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS05365	COG1741	Belongs to the pirin family
XcfCFBP6996P_RS05385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP6996P_RS05390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP6996P_RS05395	COG2137	regulation of response to DNA damage stimulus
XcfCFBP6996P_RS05405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP6996P_RS05410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6996P_RS05420	COG1546	Belongs to the CinA family
XcfCFBP6996P_RS05425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP6996P_RS05435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP6996P_RS05440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP6996P_RS05450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP6996P_RS05455	COG1534	Rna-binding protein
XcfCFBP6996P_RS05470	COG1238	metal cluster binding
XcfCFBP6996P_RS05475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6996P_RS05480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP6996P_RS05485	COG2840	Smr protein MutS2
XcfCFBP6996P_RS05490	COG0585	pseudouridine synthase activity
XcfCFBP6996P_RS05495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP6996P_RS05500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP6996P_RS05505	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP6996P_RS05510	COG0148	phosphopyruvate hydratase activity
XcfCFBP6996P_RS05525	COG0504	CTP synthase activity
XcfCFBP6996P_RS05550	COG0306	phosphate transporter
XcfCFBP6996P_RS05565	COG1253	flavin adenine dinucleotide binding
XcfCFBP6996P_RS05580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6996P_RS05585	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS05595	COG1136	(ABC) transporter
XcfCFBP6996P_RS05620	COG2264	protein methyltransferase activity
XcfCFBP6996P_RS05650	COG2244	polysaccharide biosynthetic process
XcfCFBP6996P_RS05705	COG1595	DNA-templated transcription, initiation
XcfCFBP6996P_RS05720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6996P_RS05730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6996P_RS05740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6996P_RS05755	COG4191	Histidine kinase
XcfCFBP6996P_RS05755	COG0784	Response regulator, receiver
XcfCFBP6996P_RS05760	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP6996P_RS05795	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS05835	COG3328	transposase activity
XcfCFBP6996P_RS05865	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS05870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6996P_RS05875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP6996P_RS05890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP6996P_RS05895	COG0077	Prephenate dehydratase
XcfCFBP6996P_RS05895	COG1605	Chorismate mutase
XcfCFBP6996P_RS05900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP6996P_RS05905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP6996P_RS05910	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP6996P_RS05950	COG1228	amidohydrolase
XcfCFBP6996P_RS05955	COG2986	histidine ammonia-lyase
XcfCFBP6996P_RS05965	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP6996P_RS05975	COG4993	Dehydrogenase
XcfCFBP6996P_RS05985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP6996P_RS06000	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP6996P_RS06010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6996P_RS06020	COG3115	cell septum assembly
XcfCFBP6996P_RS06035	COG0359	binds to the 23S rRNA
XcfCFBP6996P_RS06040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP6996P_RS06045	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP6996P_RS06050	COG0316	Belongs to the HesB IscA family
XcfCFBP6996P_RS06060	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP6996P_RS06145	COG0288	reversible hydration of carbon dioxide
XcfCFBP6996P_RS06150	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6996P_RS06160	COG3844	kynureninase activity
XcfCFBP6996P_RS06165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6996P_RS06170	COG2925	Exonuclease
XcfCFBP6996P_RS06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP6996P_RS06200	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP6996P_RS06200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6996P_RS06210	COG0488	(ABC) transporter
XcfCFBP6996P_RS06245	COG0494	nUDIX hydrolase
XcfCFBP6996P_RS06255	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS06265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP6996P_RS06270	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6996P_RS06295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP6996P_RS06300	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP6996P_RS06305	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP6996P_RS06310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP6996P_RS06315	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP6996P_RS06325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6996P_RS06335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6996P_RS06345	COG0557	exoribonuclease II activity
XcfCFBP6996P_RS06370	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS06385	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS06390	COG2226	methyltransferase
XcfCFBP6996P_RS06395	COG1410	methionine synthase
XcfCFBP6996P_RS06395	COG0646	methionine synthase
XcfCFBP6996P_RS06400	COG1410	methionine synthase
XcfCFBP6996P_RS06400	COG0646	methionine synthase
XcfCFBP6996P_RS06410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6996P_RS06435	COG2900	Belongs to the SlyX family
XcfCFBP6996P_RS06450	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6996P_RS06460	COG1725	Transcriptional regulator
XcfCFBP6996P_RS06465	COG1131	(ABC) transporter
XcfCFBP6996P_RS06500	COG1253	flavin adenine dinucleotide binding
XcfCFBP6996P_RS06520	COG2850	peptidyl-arginine hydroxylation
XcfCFBP6996P_RS06530	COG0567	Dehydrogenase, E1 component
XcfCFBP6996P_RS06555	COG1132	(ABC) transporter
XcfCFBP6996P_RS06565	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS06600	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP6996P_RS06610	COG0484	heat shock protein binding
XcfCFBP6996P_RS06615	COG0443	Heat shock 70 kDa protein
XcfCFBP6996P_RS06620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP6996P_RS06625	COG1420	regulation of RNA biosynthetic process
XcfCFBP6996P_RS06630	COG0497	DNA recombination
XcfCFBP6996P_RS06640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6996P_RS06655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP6996P_RS06680	COG3328	transposase activity
XcfCFBP6996P_RS06720	COG3328	transposase activity
XcfCFBP6996P_RS06815	COG2003	Belongs to the UPF0758 family
XcfCFBP6996P_RS06845	COG3706	GGDEF domain
XcfCFBP6996P_RS06890	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS06900	COG0415	Belongs to the DNA photolyase family
XcfCFBP6996P_RS06905	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6996P_RS06915	COG0367	asparagine synthase
XcfCFBP6996P_RS06935	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS06950	COG0084	hydrolase, TatD family'
XcfCFBP6996P_RS06955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP6996P_RS07010	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6996P_RS07020	COG0339	signal peptide processing
XcfCFBP6996P_RS07070	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS07075	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6996P_RS07105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6996P_RS07120	COG4774	siderophore transport
XcfCFBP6996P_RS07130	COG0367	asparagine synthase
XcfCFBP6996P_RS07135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6996P_RS07140	COG1393	Belongs to the ArsC family
XcfCFBP6996P_RS07150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP6996P_RS07190	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP6996P_RS07195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP6996P_RS07205	COG0528	UMP kinase activity
XcfCFBP6996P_RS07210	COG0233	cytoplasmic translational termination
XcfCFBP6996P_RS07215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP6996P_RS07220	COG0575	Belongs to the CDS family
XcfCFBP6996P_RS07225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP6996P_RS07230	COG0750	zinc metalloprotease
XcfCFBP6996P_RS07245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6996P_RS07250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6996P_RS07255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6996P_RS07260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6996P_RS07275	COG0825	malonyl-CoA metabolic process
XcfCFBP6996P_RS07290	COG1981	membrane
XcfCFBP6996P_RS07310	COG1695	Transcriptional regulator
XcfCFBP6996P_RS07335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6996P_RS07345	COG2040	homocysteine
XcfCFBP6996P_RS07350	COG0833	amino acid
XcfCFBP6996P_RS07355	COG0346	lactoylglutathione lyase activity
XcfCFBP6996P_RS07360	COG1131	(ABC) transporter
XcfCFBP6996P_RS07375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6996P_RS07375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6996P_RS07385	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP6996P_RS07410	COG1595	DNA-templated transcription, initiation
XcfCFBP6996P_RS07435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6996P_RS07450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6996P_RS07455	COG0251	oxidation-reduction process
XcfCFBP6996P_RS07465	COG0392	lysyltransferase activity
XcfCFBP6996P_RS07465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP6996P_RS07500	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS07505	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6996P_RS07515	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP6996P_RS07525	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6996P_RS07530	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6996P_RS07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6996P_RS07560	COG5487	UPF0391 membrane protein
XcfCFBP6996P_RS07565	COG1451	nucleotide metabolic process
XcfCFBP6996P_RS07590	COG0183	Belongs to the thiolase family
XcfCFBP6996P_RS07620	COG1793	dna ligase
XcfCFBP6996P_RS07620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6996P_RS07630	COG1793	dna ligase
XcfCFBP6996P_RS07635	COG1201	RNA secondary structure unwinding
XcfCFBP6996P_RS07645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6996P_RS07650	COG1278	Cold shock
XcfCFBP6996P_RS07655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP6996P_RS07660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP6996P_RS07665	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6996P_RS07670	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP6996P_RS07675	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP6996P_RS07680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP6996P_RS07685	COG2954	triphosphatase activity
XcfCFBP6996P_RS07690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6996P_RS07700	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP6996P_RS07705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP6996P_RS07710	COG0571	ribonuclease III activity
XcfCFBP6996P_RS07725	COG0481	GTPase activity
XcfCFBP6996P_RS07730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6996P_RS07745	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS07745	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6996P_RS07760	COG0457	Tetratricopeptide repeat
XcfCFBP6996P_RS07790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XcfCFBP6996P_RS07795	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS07800	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS07820	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP6996P_RS07825	COG3250	beta-galactosidase activity
XcfCFBP6996P_RS07845	COG2963	transposase activity
XcfCFBP6996P_RS07865	COG3209	COG3209 Rhs family protein
XcfCFBP6996P_RS07890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP6996P_RS07900	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP6996P_RS07925	COG0534	Mate efflux family protein
XcfCFBP6996P_RS07930	COG0335	large ribosomal subunit rRNA binding
XcfCFBP6996P_RS07935	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP6996P_RS07940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP6996P_RS07945	COG0228	four-way junction DNA binding
XcfCFBP6996P_RS07950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6996P_RS07960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP6996P_RS07965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6996P_RS07990	COG4191	Histidine kinase
XcfCFBP6996P_RS07990	COG0784	Response regulator, receiver
XcfCFBP6996P_RS07995	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS07995	COG3437	response regulator, receiver
XcfCFBP6996P_RS07995	COG3850	Histidine kinase
XcfCFBP6996P_RS07995	COG4999	Histidine kinase
XcfCFBP6996P_RS08000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6996P_RS08010	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS08015	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP6996P_RS08025	COG4771	TonB-dependent receptor
XcfCFBP6996P_RS08050	COG2172	sigma factor antagonist activity
XcfCFBP6996P_RS08055	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6996P_RS08060	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6996P_RS08070	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6996P_RS08075	COG2207	Transcriptional regulator
XcfCFBP6996P_RS08085	COG3152	Membrane
XcfCFBP6996P_RS08100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP6996P_RS08105	COG1845	cytochrome c oxidase, subunit III
XcfCFBP6996P_RS08110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP6996P_RS08125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP6996P_RS08130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP6996P_RS08135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP6996P_RS08140	COG0196	riboflavin kinase activity
XcfCFBP6996P_RS08150	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP6996P_RS08155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP6996P_RS08160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP6996P_RS08165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP6996P_RS08170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP6996P_RS08175	COG0824	Thioesterase
XcfCFBP6996P_RS08190	COG1946	Acyl-CoA thioesterase
XcfCFBP6996P_RS08210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP6996P_RS08220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP6996P_RS08250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP6996P_RS08265	COG2197	response regulator
XcfCFBP6996P_RS08270	COG4585	Histidine kinase
XcfCFBP6996P_RS08285	COG0850	regulation of cytokinetic process
XcfCFBP6996P_RS08290	COG2894	cell division
XcfCFBP6996P_RS08295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP6996P_RS08305	COG0642	Histidine kinase
XcfCFBP6996P_RS08310	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS08325	COG2194	sulfuric ester hydrolase activity
XcfCFBP6996P_RS08340	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS08345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6996P_RS08345	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6996P_RS08355	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP6996P_RS08360	COG0753	catalase activity
XcfCFBP6996P_RS08390	COG2207	Transcriptional regulator
XcfCFBP6996P_RS08390	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP6996P_RS08410	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6996P_RS08410	COG1506	peptidase
XcfCFBP6996P_RS08425	COG1297	OPT oligopeptide transporter protein
XcfCFBP6996P_RS08440	COG0587	DNA-directed DNA polymerase activity
XcfCFBP6996P_RS08455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6996P_RS08490	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6996P_RS08495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6996P_RS08500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6996P_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS08550	COG3537	Alpha-1,2-mannosidase
XcfCFBP6996P_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS08565	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6996P_RS08575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6996P_RS08645	COG1309	transcriptional regulator
XcfCFBP6996P_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS08660	COG0308	aminopeptidase N
XcfCFBP6996P_RS08665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP6996P_RS08675	COG0330	HflC and HflK could
XcfCFBP6996P_RS08680	COG0330	HflC and HflK could
XcfCFBP6996P_RS08700	COG0678	peroxiredoxin activity
XcfCFBP6996P_RS08710	COG4953	penicillin-binding protein 1C
XcfCFBP6996P_RS08730	COG2373	Large extracellular alpha-helical protein
XcfCFBP6996P_RS08760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XcfCFBP6996P_RS08775	COG3829	transcription factor binding
XcfCFBP6996P_RS08800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP6996P_RS08805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP6996P_RS08825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6996P_RS08835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6996P_RS08845	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP6996P_RS08850	COG0424	maF-like protein
XcfCFBP6996P_RS08875	COG0714	Associated with various cellular activities
XcfCFBP6996P_RS08895	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP6996P_RS08900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP6996P_RS08905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP6996P_RS08925	COG0314	molybdopterin synthase activity
XcfCFBP6996P_RS08930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP6996P_RS08935	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP6996P_RS08945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP6996P_RS08950	COG1234	tRNA 3'-trailer cleavage
XcfCFBP6996P_RS08955	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP6996P_RS08960	COG0859	PFAM glycosyl transferase family 9
XcfCFBP6996P_RS08975	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6996P_RS08980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6996P_RS08985	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP6996P_RS08995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6996P_RS09010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6996P_RS09040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP6996P_RS09050	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP6996P_RS09060	COG3852	Histidine kinase
XcfCFBP6996P_RS09065	COG2201	protein-glutamate methylesterase activity
XcfCFBP6996P_RS09080	COG3328	transposase activity
XcfCFBP6996P_RS09125	COG4695	Portal protein
XcfCFBP6996P_RS09385	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6996P_RS09400	COG4783	chaperone-mediated protein folding
XcfCFBP6996P_RS09415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP6996P_RS09425	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS09430	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6996P_RS09435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6996P_RS09455	COG2833	Protein of unknown function (DUF455)
XcfCFBP6996P_RS09475	COG0285	dihydrofolate synthase activity
XcfCFBP6996P_RS09480	COG0406	alpha-ribazole phosphatase activity
XcfCFBP6996P_RS09510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP6996P_RS09515	COG4208	sulfate ABC transporter
XcfCFBP6996P_RS09520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP6996P_RS09525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcfCFBP6996P_RS09530	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6996P_RS09565	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6996P_RS09565	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP6996P_RS09580	COG0625	glutathione transferase activity
XcfCFBP6996P_RS09585	COG0039	L-malate dehydrogenase activity
XcfCFBP6996P_RS09590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP6996P_RS09595	COG1217	gtp-binding protein TYPA
XcfCFBP6996P_RS09605	COG0154	amidase activity
XcfCFBP6996P_RS09620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP6996P_RS09640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP6996P_RS09645	COG0203	ribosomal protein L17
XcfCFBP6996P_RS09670	COG0201	protein transport
XcfCFBP6996P_RS09675	COG0200	Binds to the 23S rRNA
XcfCFBP6996P_RS09680	COG1841	ribosomal large subunit assembly
XcfCFBP6996P_RS09690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP6996P_RS09695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP6996P_RS09700	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP6996P_RS09710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP6996P_RS09715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP6996P_RS09725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP6996P_RS09730	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP6996P_RS09735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP6996P_RS09740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP6996P_RS09750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP6996P_RS09755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP6996P_RS09760	COG0089	rRNA binding
XcfCFBP6996P_RS09765	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP6996P_RS09770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP6996P_RS09775	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP6996P_RS09780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6996P_RS09785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP6996P_RS09790	COG0049	tRNA binding
XcfCFBP6996P_RS09795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP6996P_RS09800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP6996P_RS09805	COG0085	RNA polymerase activity
XcfCFBP6996P_RS09810	COG0222	ribosome binding
XcfCFBP6996P_RS09815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP6996P_RS09820	COG0081	regulation of translation
XcfCFBP6996P_RS09825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP6996P_RS09830	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP6996P_RS09845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6996P_RS09865	COG0012	GTP binding
XcfCFBP6996P_RS09870	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP6996P_RS09875	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP6996P_RS09880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP6996P_RS09890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP6996P_RS09895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP6996P_RS09905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP6996P_RS09910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP6996P_RS09920	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP6996P_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6996P_RS09945	COG1295	ribonuclease BN
XcfCFBP6996P_RS09970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP6996P_RS09975	COG1404	Belongs to the peptidase S8 family
XcfCFBP6996P_RS09980	COG1404	Belongs to the peptidase S8 family
XcfCFBP6996P_RS09985	COG1404	Belongs to the peptidase S8 family
XcfCFBP6996P_RS09990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6996P_RS10010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XcfCFBP6996P_RS10035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP6996P_RS10065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6996P_RS10065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6996P_RS10085	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6996P_RS10095	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP6996P_RS10100	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS10110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6996P_RS10115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP6996P_RS10125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP6996P_RS10135	COG2197	response regulator
XcfCFBP6996P_RS10160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6996P_RS10170	COG0697	spore germination
XcfCFBP6996P_RS10195	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP6996P_RS10225	COG1024	Enoyl-CoA hydratase
XcfCFBP6996P_RS10240	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS10245	COG3384	dioxygenase
XcfCFBP6996P_RS10275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6996P_RS10280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6996P_RS10295	COG2096	Adenosyltransferase
XcfCFBP6996P_RS10300	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP6996P_RS10305	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP6996P_RS10310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6996P_RS10315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP6996P_RS10320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP6996P_RS10325	COG2967	ApaG domain
XcfCFBP6996P_RS10330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP6996P_RS10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP6996P_RS10350	COG0747	negative chemotaxis
XcfCFBP6996P_RS10370	COG0431	NADPH-dependent FMN reductase
XcfCFBP6996P_RS10375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6996P_RS10385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6996P_RS10390	COG1116	anion transmembrane transporter activity
XcfCFBP6996P_RS10400	COG3829	transcription factor binding
XcfCFBP6996P_RS10415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP6996P_RS10420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP6996P_RS10440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP6996P_RS10450	COG0642	Histidine kinase
XcfCFBP6996P_RS10465	COG4181	ATPase activity
XcfCFBP6996P_RS10475	COG2175	clavaminate synthase activity
XcfCFBP6996P_RS10485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP6996P_RS10490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6996P_RS10520	COG0667	Aldo Keto reductase
XcfCFBP6996P_RS10530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP6996P_RS10535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6996P_RS10545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6996P_RS10550	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6996P_RS10560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP6996P_RS10600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP6996P_RS10610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP6996P_RS10615	COG2226	methyltransferase
XcfCFBP6996P_RS10650	COG0366	Alpha amylase catalytic
XcfCFBP6996P_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS10675	COG0604	alcohol dehydrogenase
XcfCFBP6996P_RS10675	COG3321	synthase
XcfCFBP6996P_RS10690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP6996P_RS10700	COG0494	nUDIX hydrolase
XcfCFBP6996P_RS10705	COG0653	protein targeting
XcfCFBP6996P_RS10710	COG0739	heme binding
XcfCFBP6996P_RS10720	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP6996P_RS10735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP6996P_RS10740	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6996P_RS10745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6996P_RS10750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP6996P_RS10760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6996P_RS10765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP6996P_RS10770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP6996P_RS10785	COG3116	cell division
XcfCFBP6996P_RS10790	COG0275	rRNA processing
XcfCFBP6996P_RS10825	COG0792	nuclease activity
XcfCFBP6996P_RS10830	COG1988	membrane-bound metal-dependent
XcfCFBP6996P_RS10835	COG0277	FAD linked oxidase domain protein
XcfCFBP6996P_RS10840	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS10845	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS10850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP6996P_RS10855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP6996P_RS10860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP6996P_RS10885	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP6996P_RS10890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6996P_RS10895	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP6996P_RS10915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6996P_RS10915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6996P_RS10925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP6996P_RS10930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP6996P_RS10940	COG0488	(ABC) transporter
XcfCFBP6996P_RS10950	COG0697	spore germination
XcfCFBP6996P_RS10960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6996P_RS10975	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP6996P_RS11005	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS11025	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6996P_RS11030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP6996P_RS11045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6996P_RS11060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP6996P_RS11065	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6996P_RS11070	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6996P_RS11075	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP6996P_RS11090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP6996P_RS11095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6996P_RS11100	COG1609	Transcriptional regulator
XcfCFBP6996P_RS11110	COG2188	Transcriptional regulator
XcfCFBP6996P_RS11125	COG3250	beta-galactosidase activity
XcfCFBP6996P_RS11155	COG4795	General secretion pathway protein
XcfCFBP6996P_RS11175	COG1459	type II secretion system
XcfCFBP6996P_RS11230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP6996P_RS11235	COG4191	Histidine kinase
XcfCFBP6996P_RS11240	COG0784	Response regulator, receiver
XcfCFBP6996P_RS11245	COG4251	negative regulation of phosphorylation
XcfCFBP6996P_RS11250	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP6996P_RS11255	COG0673	inositol 2-dehydrogenase activity
XcfCFBP6996P_RS11260	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP6996P_RS11295	COG1051	belongs to the nudix hydrolase family
XcfCFBP6996P_RS11295	COG1056	cytidyltransferase-related domain
XcfCFBP6996P_RS11305	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS11320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP6996P_RS11325	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP6996P_RS11330	COG2921	Belongs to the UPF0250 family
XcfCFBP6996P_RS11340	COG1686	Belongs to the peptidase S11 family
XcfCFBP6996P_RS11350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP6996P_RS11355	COG2951	lytic endotransglycosylase activity
XcfCFBP6996P_RS11365	COG0772	Belongs to the SEDS family
XcfCFBP6996P_RS11380	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP6996P_RS11385	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6996P_RS11390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6996P_RS11395	COG3284	Transcriptional regulator
XcfCFBP6996P_RS11445	COG0308	aminopeptidase N
XcfCFBP6996P_RS11450	COG5001	Diguanylate cyclase
XcfCFBP6996P_RS11450	COG3300	MHYT domain
XcfCFBP6996P_RS11455	COG2226	methyltransferase
XcfCFBP6996P_RS11480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP6996P_RS11485	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP6996P_RS11490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP6996P_RS11500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP6996P_RS11510	COG2832	Protein of unknown function (DUF454)
XcfCFBP6996P_RS11520	COG0436	Aminotransferase
XcfCFBP6996P_RS11525	COG1505	serine-type exopeptidase activity
XcfCFBP6996P_RS11555	COG0181	hydroxymethylbilane synthase activity
XcfCFBP6996P_RS11565	COG3275	phosphorelay sensor kinase activity
XcfCFBP6996P_RS11575	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP6996P_RS11600	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6996P_RS11605	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6996P_RS11605	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6996P_RS11610	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS11665	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP6996P_RS11685	COG1113	amino acid transport
XcfCFBP6996P_RS11695	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6996P_RS11700	COG4305	rare lipoprotein A
XcfCFBP6996P_RS11750	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6996P_RS11750	COG1506	peptidase
XcfCFBP6996P_RS11785	COG0435	Glutathione S-transferase
XcfCFBP6996P_RS11795	COG4221	oxidoreductase activity
XcfCFBP6996P_RS11810	COG4221	oxidoreductase activity
XcfCFBP6996P_RS11830	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6996P_RS11860	COG3328	transposase activity
XcfCFBP6996P_RS11995	COG1802	Transcriptional regulator
XcfCFBP6996P_RS12005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6996P_RS12030	COG3052	prosthetic group binding
XcfCFBP6996P_RS12060	COG2353	YceI-like domain
XcfCFBP6996P_RS12065	COG0778	Nitroreductase
XcfCFBP6996P_RS12090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6996P_RS12095	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP6996P_RS12105	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6996P_RS12120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP6996P_RS12135	COG0459	protein refolding
XcfCFBP6996P_RS12145	COG2356	endonuclease I
XcfCFBP6996P_RS12155	COG1324	tolerance protein
XcfCFBP6996P_RS12165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP6996P_RS12170	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP6996P_RS12180	COG0439	Biotin carboxylase
XcfCFBP6996P_RS12200	COG2264	protein methyltransferase activity
XcfCFBP6996P_RS12225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP6996P_RS12230	COG4589	Belongs to the CDS family
XcfCFBP6996P_RS12255	COG2453	phosphatase
XcfCFBP6996P_RS12255	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6996P_RS12260	COG2267	carboxylic ester hydrolase activity
XcfCFBP6996P_RS12265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6996P_RS12270	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP6996P_RS12280	COG0151	Belongs to the GarS family
XcfCFBP6996P_RS12285	COG1289	transmembrane transporter activity
XcfCFBP6996P_RS12290	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS12300	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS12320	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6996P_RS12335	COG0316	Belongs to the HesB IscA family
XcfCFBP6996P_RS12375	COG1051	belongs to the nudix hydrolase family
XcfCFBP6996P_RS12390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP6996P_RS12400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP6996P_RS12410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP6996P_RS12415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6996P_RS12425	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP6996P_RS12430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP6996P_RS12455	COG1597	lipid kinase activity
XcfCFBP6996P_RS12460	COG0456	acetyltransferase
XcfCFBP6996P_RS12475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP6996P_RS12480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP6996P_RS12505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6996P_RS12505	COG2111	Na H antiporter
XcfCFBP6996P_RS12510	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP6996P_RS12515	COG0651	ATP synthesis coupled electron transport
XcfCFBP6996P_RS12525	COG2212	antiporter activity
XcfCFBP6996P_RS12530	COG1320	monovalent cation:proton antiporter activity
XcfCFBP6996P_RS12550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcfCFBP6996P_RS12570	COG3104	oligopeptide transport
XcfCFBP6996P_RS12575	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP6996P_RS12590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP6996P_RS12605	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6996P_RS12610	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6996P_RS12620	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS12625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6996P_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS12670	COG3328	transposase activity
XcfCFBP6996P_RS12685	COG1858	cytochrome C peroxidase
XcfCFBP6996P_RS12690	COG0702	epimerase
XcfCFBP6996P_RS12715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6996P_RS12720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6996P_RS12725	COG0297	glycogen (starch) synthase activity
XcfCFBP6996P_RS12735	COG2354	Protein conserved in bacteria
XcfCFBP6996P_RS12740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6996P_RS12750	COG1368	sulfuric ester hydrolase activity
XcfCFBP6996P_RS12830	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP6996P_RS12915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6996P_RS12920	COG1040	competence protein
XcfCFBP6996P_RS12925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP6996P_RS12930	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6996P_RS12940	COG2267	carboxylic ester hydrolase activity
XcfCFBP6996P_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS12970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP6996P_RS12980	COG0445	tRNA wobble uridine modification
XcfCFBP6996P_RS12990	COG0657	acetylesterase activity
XcfCFBP6996P_RS13000	COG1414	Transcriptional regulator
XcfCFBP6996P_RS13010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP6996P_RS13015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6996P_RS13025	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6996P_RS13030	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6996P_RS13040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP6996P_RS13045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP6996P_RS13075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP6996P_RS13080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP6996P_RS13140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP6996P_RS13155	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6996P_RS13185	COG1733	regulation of RNA biosynthetic process
XcfCFBP6996P_RS13190	COG0702	epimerase
XcfCFBP6996P_RS13220	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS13225	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6996P_RS13250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS13255	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS13260	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS13280	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6996P_RS13285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP6996P_RS13290	COG2267	carboxylic ester hydrolase activity
XcfCFBP6996P_RS13300	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS13305	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS13315	COG0084	hydrolase, TatD family'
XcfCFBP6996P_RS13340	COG2252	PERMEase
XcfCFBP6996P_RS13375	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS13385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP6996P_RS13405	COG2072	flavoprotein involved in K transport
XcfCFBP6996P_RS13410	COG2351	hydroxyisourate hydrolase activity
XcfCFBP6996P_RS13415	COG4807	Protein conserved in bacteria
XcfCFBP6996P_RS13425	COG1643	Atp-dependent helicase
XcfCFBP6996P_RS13440	COG1187	pseudouridine synthase activity
XcfCFBP6996P_RS13455	COG2130	NADP-dependent
XcfCFBP6996P_RS13485	COG1764	response to oxidative stress
XcfCFBP6996P_RS13490	COG1846	Transcriptional regulator
XcfCFBP6996P_RS13495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP6996P_RS13505	COG0697	spore germination
XcfCFBP6996P_RS13570	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS13575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP6996P_RS13580	COG4770	biotin carboxylase activity
XcfCFBP6996P_RS13610	COG2224	Isocitrate lyase
XcfCFBP6996P_RS13615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP6996P_RS13620	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS13625	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6996P_RS13665	COG0339	signal peptide processing
XcfCFBP6996P_RS13670	COG1446	asparaginase
XcfCFBP6996P_RS13690	COG0564	pseudouridine synthase activity
XcfCFBP6996P_RS13700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6996P_RS13715	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6996P_RS13735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6996P_RS13745	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS13750	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6996P_RS13755	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP6996P_RS13760	COG0596	Alpha beta hydrolase
XcfCFBP6996P_RS13770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6996P_RS13785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP6996P_RS13810	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS13815	COG0028	Belongs to the TPP enzyme family
XcfCFBP6996P_RS13830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP6996P_RS13835	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP6996P_RS13840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP6996P_RS13875	COG0183	Belongs to the thiolase family
XcfCFBP6996P_RS13885	COG0346	lactoylglutathione lyase activity
XcfCFBP6996P_RS13890	COG2032	superoxide dismutase activity
XcfCFBP6996P_RS13895	COG2032	superoxide dismutase activity
XcfCFBP6996P_RS13900	COG2204	response regulator
XcfCFBP6996P_RS13905	COG3852	Histidine kinase
XcfCFBP6996P_RS13910	COG0004	ammonium transporteR
XcfCFBP6996P_RS13915	COG0347	Belongs to the P(II) protein family
XcfCFBP6996P_RS13920	COG0174	glutamine synthetase
XcfCFBP6996P_RS13930	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP6996P_RS13975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS13985	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP6996P_RS13990	COG0489	protein tyrosine kinase activity
XcfCFBP6996P_RS14020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6996P_RS14035	COG1125	glycine betaine transport
XcfCFBP6996P_RS14050	COG1119	ATPase activity
XcfCFBP6996P_RS14060	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP6996P_RS14070	COG1522	sequence-specific DNA binding
XcfCFBP6996P_RS14075	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP6996P_RS14085	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6996P_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS14100	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP6996P_RS14115	COG1609	Transcriptional regulator
XcfCFBP6996P_RS14120	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6996P_RS14135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP6996P_RS14145	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6996P_RS14145	COG0657	acetylesterase activity
XcfCFBP6996P_RS14165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6996P_RS14170	COG0366	Alpha amylase catalytic
XcfCFBP6996P_RS14175	COG0366	Alpha amylase catalytic
XcfCFBP6996P_RS14275	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP6996P_RS14280	COG3710	Transcriptional regulator
XcfCFBP6996P_RS14300	COG2197	response regulator
XcfCFBP6996P_RS14305	COG4585	Histidine kinase
XcfCFBP6996P_RS14320	COG1304	FMN binding
XcfCFBP6996P_RS14345	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6996P_RS14360	COG4772	TonB-dependent receptor
XcfCFBP6996P_RS14370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP6996P_RS14405	COG0714	Associated with various cellular activities
XcfCFBP6996P_RS14455	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS14465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6996P_RS14515	COG3237	CsbD-like
XcfCFBP6996P_RS14555	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP6996P_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS14575	COG0300	oxidoreductase activity
XcfCFBP6996P_RS14595	COG1272	protein, Hemolysin III
XcfCFBP6996P_RS14600	COG1111	helicase
XcfCFBP6996P_RS14600	COG1205	dead DEAH box helicase
XcfCFBP6996P_RS14695	COG0069	glutamate synthase activity
XcfCFBP6996P_RS14695	COG0067	glutamate synthase
XcfCFBP6996P_RS14695	COG0070	glutamate synthase
XcfCFBP6996P_RS14700	COG0493	'glutamate synthase
XcfCFBP6996P_RS14715	COG1064	alcohol dehydrogenase
XcfCFBP6996P_RS14725	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6996P_RS14730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6996P_RS14735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6996P_RS14745	COG2234	aminopeptidase activity
XcfCFBP6996P_RS14755	COG4942	peptidase
XcfCFBP6996P_RS14760	COG0793	Belongs to the peptidase S41A family
XcfCFBP6996P_RS14810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS14820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP6996P_RS14855	COG0501	Belongs to the peptidase M48B family
XcfCFBP6996P_RS14865	COG0187	DNA topoisomerase II activity
XcfCFBP6996P_RS14870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6996P_RS14880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcfCFBP6996P_RS14895	COG0594	ribonuclease P activity
XcfCFBP6996P_RS14900	COG0706	membrane insertase activity
XcfCFBP6996P_RS14915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP6996P_RS14930	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP6996P_RS14940	COG0861	Integral membrane protein TerC family
XcfCFBP6996P_RS14950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6996P_RS14965	COG2271	Major facilitator Superfamily
XcfCFBP6996P_RS14970	COG1929	Belongs to the glycerate kinase type-1 family
XcfCFBP6996P_RS14975	COG3835	regulator
XcfCFBP6996P_RS14980	COG3706	GGDEF domain
XcfCFBP6996P_RS14995	COG3537	Alpha-1,2-mannosidase
XcfCFBP6996P_RS15000	COG0531	amino acid
XcfCFBP6996P_RS15010	COG0625	glutathione transferase activity
XcfCFBP6996P_RS15025	COG1322	Protein conserved in bacteria
XcfCFBP6996P_RS15035	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6996P_RS15045	COG2853	Lipoprotein
XcfCFBP6996P_RS15060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6996P_RS15065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6996P_RS15070	COG1127	ABC transporter
XcfCFBP6996P_RS15105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP6996P_RS15110	COG1074	ATP-dependent DNA helicase activity
XcfCFBP6996P_RS15115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP6996P_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS15200	COG0564	pseudouridine synthase activity
XcfCFBP6996P_RS15280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS15295	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS15305	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS15310	COG1289	transmembrane transporter activity
XcfCFBP6996P_RS15320	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6996P_RS15335	COG0302	gtp cyclohydrolase
XcfCFBP6996P_RS15365	COG0730	response to heat
XcfCFBP6996P_RS15370	COG3012	SEC-C Motif Domain Protein
XcfCFBP6996P_RS15380	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP6996P_RS15405	COG3135	benzoate transporter
XcfCFBP6996P_RS15435	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP6996P_RS15445	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP6996P_RS15455	COG1435	thymidine kinase activity
XcfCFBP6996P_RS15460	COG0210	DNA helicase
XcfCFBP6996P_RS15475	COG3132	Protein of unknown function, DUF480
XcfCFBP6996P_RS15485	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP6996P_RS15490	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP6996P_RS15525	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP6996P_RS15530	COG3321	synthase
XcfCFBP6996P_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS15530	COG0604	alcohol dehydrogenase
XcfCFBP6996P_RS15565	COG2211	Major facilitator Superfamily
XcfCFBP6996P_RS15580	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6996P_RS15590	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6996P_RS15595	COG1904	glucuronate isomerase
XcfCFBP6996P_RS15600	COG3250	beta-galactosidase activity
XcfCFBP6996P_RS15610	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6996P_RS15640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6996P_RS15690	COG0246	Mannitol dehydrogenase
XcfCFBP6996P_RS15695	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6996P_RS15705	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6996P_RS15715	COG3661	Belongs to the glycosyl hydrolase 67 family
XcfCFBP6996P_RS15725	COG2115	Belongs to the xylose isomerase family
XcfCFBP6996P_RS15730	COG0037	tRNA processing
XcfCFBP6996P_RS15735	COG2974	May be involved in recombination
XcfCFBP6996P_RS15755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP6996P_RS15765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6996P_RS15770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6996P_RS15775	COG0805	protein transport
XcfCFBP6996P_RS15785	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6996P_RS15785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6996P_RS15800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6996P_RS15805	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP6996P_RS15835	COG0729	surface antigen
XcfCFBP6996P_RS15840	COG2911	Protein conserved in bacteria
XcfCFBP6996P_RS15865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6996P_RS15875	COG3265	gluconokinase activity
XcfCFBP6996P_RS15880	COG2211	Major facilitator Superfamily
XcfCFBP6996P_RS15885	COG3459	Glycosyltransferase 36 associated
XcfCFBP6996P_RS15900	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS15905	COG1971	Probably functions as a manganese efflux pump
XcfCFBP6996P_RS15910	COG1414	Transcriptional regulator
XcfCFBP6996P_RS15915	COG0738	Major facilitator superfamily
XcfCFBP6996P_RS15920	COG3254	rhamnose metabolic process
XcfCFBP6996P_RS15925	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6996P_RS15930	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP6996P_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS15955	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6996P_RS15985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP6996P_RS15995	COG3162	membrane
XcfCFBP6996P_RS16000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP6996P_RS16015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6996P_RS16025	COG1940	carbohydrate kinase activity
XcfCFBP6996P_RS16025	COG1846	Transcriptional regulator
XcfCFBP6996P_RS16030	COG0708	Exodeoxyribonuclease III
XcfCFBP6996P_RS16045	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP6996P_RS16055	COG3540	Alkaline phosphatase
XcfCFBP6996P_RS16060	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP6996P_RS16080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS16110	COG2159	amidohydrolase
XcfCFBP6996P_RS16125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6996P_RS16130	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS16135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS16145	COG0210	DNA helicase
XcfCFBP6996P_RS16335	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6996P_RS16340	COG0515	serine threonine protein kinase
XcfCFBP6996P_RS16380	COG0408	coproporphyrinogen oxidase activity
XcfCFBP6996P_RS16400	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6996P_RS16400	COG4946	Tricorn protease homolog
XcfCFBP6996P_RS16400	COG1506	peptidase
XcfCFBP6996P_RS16430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6996P_RS16445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6996P_RS16485	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS16505	COG0463	Glycosyl transferase, family 2
XcfCFBP6996P_RS16515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6996P_RS16520	COG3100	YcgL domain-containing protein
XcfCFBP6996P_RS16535	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6996P_RS16540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6996P_RS16565	COG2239	Acts as a magnesium transporter
XcfCFBP6996P_RS16570	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6996P_RS16570	COG1042	CoA-binding domain protein
XcfCFBP6996P_RS16570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcfCFBP6996P_RS16585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6996P_RS16595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6996P_RS16625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP6996P_RS16630	COG0842	Transport permease protein
XcfCFBP6996P_RS16635	COG1131	(ABC) transporter
XcfCFBP6996P_RS16640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6996P_RS16665	COG1230	cation diffusion facilitator family transporter
XcfCFBP6996P_RS16685	COG1476	TRANSCRIPTIONal
XcfCFBP6996P_RS16695	COG4555	ABC transporter
XcfCFBP6996P_RS16730	COG0625	glutathione transferase activity
XcfCFBP6996P_RS16810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP6996P_RS16825	COG1199	ATP-dependent helicase activity
XcfCFBP6996P_RS16855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6996P_RS16905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP6996P_RS16925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP6996P_RS16965	COG3237	CsbD-like
XcfCFBP6996P_RS16970	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP6996P_RS16975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6996P_RS16995	COG0697	spore germination
XcfCFBP6996P_RS17020	COG1136	(ABC) transporter
XcfCFBP6996P_RS17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS17030	COG4585	Histidine kinase
XcfCFBP6996P_RS17035	COG2197	response regulator
XcfCFBP6996P_RS17065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6996P_RS17070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6996P_RS17095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6996P_RS17120	COG0642	Histidine kinase
XcfCFBP6996P_RS17130	COG1090	epimerase
XcfCFBP6996P_RS17165	COG1690	Belongs to the RtcB family
XcfCFBP6996P_RS17200	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP6996P_RS17215	COG0606	chelatase, subunit chli
XcfCFBP6996P_RS17235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6996P_RS17235	COG3291	Pkd domain containing protein
XcfCFBP6996P_RS17260	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP6996P_RS17265	COG1166	arginine decarboxylase activity
XcfCFBP6996P_RS17285	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6996P_RS17285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP6996P_RS17290	COG4221	oxidoreductase activity
XcfCFBP6996P_RS17305	COG0018	arginyl-trna synthetase
XcfCFBP6996P_RS17310	COG2003	Belongs to the UPF0758 family
XcfCFBP6996P_RS17315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP6996P_RS17320	COG0756	dUTP diphosphatase activity
XcfCFBP6996P_RS17340	COG0463	Glycosyl transferase, family 2
XcfCFBP6996P_RS17360	COG1475	DNA binding
XcfCFBP6996P_RS17365	COG1192	Involved in chromosome partitioning
XcfCFBP6996P_RS17375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP6996P_RS17380	COG0708	Exodeoxyribonuclease III
XcfCFBP6996P_RS17385	COG2211	Major facilitator Superfamily
XcfCFBP6996P_RS17395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP6996P_RS17400	COG0739	heme binding
XcfCFBP6996P_RS17405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP6996P_RS17450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP6996P_RS17465	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP6996P_RS17495	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP6996P_RS17510	COG0358	DNA primase activity
XcfCFBP6996P_RS17515	COG1295	ribonuclease BN
XcfCFBP6996P_RS17525	COG1610	YqeY-like protein
XcfCFBP6996P_RS17535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP6996P_RS17540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP6996P_RS17550	COG2133	pyrroloquinoline quinone binding
XcfCFBP6996P_RS17555	COG4682	membrane
XcfCFBP6996P_RS17570	COG0531	amino acid
XcfCFBP6996P_RS17580	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6996P_RS17590	COG3023	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6996P_RS17595	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XcfCFBP6996P_RS17640	COG5383	Protein conserved in bacteria
XcfCFBP6996P_RS17660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6996P_RS17665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS17670	COG1473	amidohydrolase
XcfCFBP6996P_RS17675	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6996P_RS17675	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6996P_RS17680	COG1652	LysM domain
XcfCFBP6996P_RS17700	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS17705	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcfCFBP6996P_RS17710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP6996P_RS17715	COG3118	belongs to the thioredoxin family
XcfCFBP6996P_RS17720	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6996P_RS17725	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP6996P_RS17730	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP6996P_RS17735	COG3437	response regulator, receiver
XcfCFBP6996P_RS17740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP6996P_RS17745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6996P_RS17750	COG2860	membrane
XcfCFBP6996P_RS17755	COG1252	NADH dehydrogenase
XcfCFBP6996P_RS17770	COG0625	glutathione transferase activity
XcfCFBP6996P_RS17795	COG0534	Mate efflux family protein
XcfCFBP6996P_RS17800	COG0616	signal peptide processing
XcfCFBP6996P_RS17815	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS17830	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP6996P_RS17835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6996P_RS17835	COG1754	DNA topoisomerase type I activity
XcfCFBP6996P_RS17855	COG0758	DNA mediated transformation
XcfCFBP6996P_RS17860	COG1652	LysM domain
XcfCFBP6996P_RS17865	COG0242	peptide deformylase activity
XcfCFBP6996P_RS17870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP6996P_RS17875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP6996P_RS17875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6996P_RS17930	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6996P_RS17935	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP6996P_RS17940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6996P_RS18010	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XcfCFBP6996P_RS18010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6996P_RS18020	COG1487	ribonuclease activity
XcfCFBP6996P_RS18045	COG0024	Methionine aminopeptidase
XcfCFBP6996P_RS18055	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6996P_RS18085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6996P_RS18090	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS18105	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS18120	COG0251	oxidation-reduction process
XcfCFBP6996P_RS18195	COG1063	alcohol dehydrogenase
XcfCFBP6996P_RS18210	COG1132	(ABC) transporter
XcfCFBP6996P_RS18230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP6996P_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS18250	COG1294	oxidase, subunit
XcfCFBP6996P_RS18255	COG1271	oxidase subunit
XcfCFBP6996P_RS18270	COG2204	response regulator
XcfCFBP6996P_RS18305	COG3546	catalase activity
XcfCFBP6996P_RS18310	COG3685	Protein conserved in bacteria
XcfCFBP6996P_RS18335	COG2972	Histidine kinase
XcfCFBP6996P_RS18350	COG0531	amino acid
XcfCFBP6996P_RS18365	COG3590	peptidase
XcfCFBP6996P_RS18380	COG0667	Aldo Keto reductase
XcfCFBP6996P_RS18390	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS18400	COG3384	dioxygenase
XcfCFBP6996P_RS18410	COG1573	uracil-dna glycosylase
XcfCFBP6996P_RS18415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP6996P_RS18425	COG0025	NhaP-type Na H and K H
XcfCFBP6996P_RS18430	COG1131	(ABC) transporter
XcfCFBP6996P_RS18435	COG0842	Transport permease protein
XcfCFBP6996P_RS18495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6996P_RS18500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP6996P_RS18520	COG2202	Pas domain
XcfCFBP6996P_RS18520	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS18540	COG2813	Specifically methylates the guanine in position
XcfCFBP6996P_RS18545	COG1187	pseudouridine synthase activity
XcfCFBP6996P_RS18550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6996P_RS18570	COG0784	Response regulator, receiver
XcfCFBP6996P_RS18570	COG2198	Histidine kinase
XcfCFBP6996P_RS18570	COG5002	protein histidine kinase activity
XcfCFBP6996P_RS18580	COG1666	GTP binding
XcfCFBP6996P_RS18585	COG0697	spore germination
XcfCFBP6996P_RS18590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP6996P_RS18595	COG2011	ABC-type metal ion transport system permease component
XcfCFBP6996P_RS18630	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6996P_RS18640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6996P_RS18660	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP6996P_RS18670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP6996P_RS18675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP6996P_RS18680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP6996P_RS18685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP6996P_RS18690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP6996P_RS18695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP6996P_RS18710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP6996P_RS18720	COG3328	transposase activity
XcfCFBP6996P_RS18745	COG0577	efflux transmembrane transporter activity
XcfCFBP6996P_RS18750	COG1136	(ABC) transporter
XcfCFBP6996P_RS18755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6996P_RS18760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6996P_RS18795	COG2132	Multicopper oxidase
XcfCFBP6996P_RS18810	COG0339	signal peptide processing
XcfCFBP6996P_RS18825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6996P_RS18830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6996P_RS18835	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6996P_RS18845	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP6996P_RS18855	COG1956	GAF domain-containing protein
XcfCFBP6996P_RS18860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP6996P_RS18870	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XcfCFBP6996P_RS18880	COG0720	synthase
XcfCFBP6996P_RS18890	COG4206	TonB-dependent receptor
XcfCFBP6996P_RS18900	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6996P_RS18915	COG0625	glutathione transferase activity
XcfCFBP6996P_RS18945	COG0626	cystathionine gamma-synthase activity
XcfCFBP6996P_RS18970	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcfCFBP6996P_RS18985	COG0463	Glycosyl transferase, family 2
XcfCFBP6996P_RS19005	COG0463	Glycosyl transferase, family 2
XcfCFBP6996P_RS19010	COG3328	transposase activity
XcfCFBP6996P_RS19015	COG2226	methyltransferase
XcfCFBP6996P_RS19030	COG2086	electron transfer activity
XcfCFBP6996P_RS19060	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6996P_RS19060	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP6996P_RS19065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6996P_RS19095	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP6996P_RS19095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6996P_RS19100	COG1127	ABC transporter
XcfCFBP6996P_RS19105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6996P_RS19120	COG0442	prolyl-tRNA aminoacylation
XcfCFBP6996P_RS19130	COG1183	phosphatidylcholine synthase activity
XcfCFBP6996P_RS19165	COG0525	valine-tRNA ligase activity
XcfCFBP6996P_RS19180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6996P_RS19190	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP6996P_RS19205	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6996P_RS19220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6996P_RS19235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP6996P_RS19235	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP6996P_RS19240	COG5295	Hep Hag repeat protein
XcfCFBP6996P_RS19245	COG1404	Belongs to the peptidase S8 family
XcfCFBP6996P_RS19250	COG5295	Hep Hag repeat protein
XcfCFBP6996P_RS19255	COG1404	Belongs to the peptidase S8 family
XcfCFBP6996P_RS19260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6996P_RS19270	COG1459	type II secretion system
XcfCFBP6996P_RS19275	COG2165	general secretion pathway protein
XcfCFBP6996P_RS19280	COG4970	Tfp pilus assembly protein FimT
XcfCFBP6996P_RS19285	COG2165	general secretion pathway protein
XcfCFBP6996P_RS19290	COG4795	General secretion pathway protein
XcfCFBP6996P_RS19295	COG3156	type II secretion system protein K
XcfCFBP6996P_RS19300	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP6996P_RS19315	COG1450	Type ii and iii secretion system protein
XcfCFBP6996P_RS19325	COG2188	Transcriptional regulator
XcfCFBP6996P_RS19380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP6996P_RS19395	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS19400	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6996P_RS19405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP6996P_RS19410	COG0457	Tetratricopeptide repeat
XcfCFBP6996P_RS19440	COG0242	peptide deformylase activity
XcfCFBP6996P_RS19445	COG1307	EDD domain protein, DegV family
XcfCFBP6996P_RS19465	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6996P_RS19470	COG3964	amidohydrolase
XcfCFBP6996P_RS19485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6996P_RS19490	COG0726	polysaccharide deacetylase
XcfCFBP6996P_RS19505	COG0436	Aminotransferase
XcfCFBP6996P_RS19510	COG1162	GTPase activity
XcfCFBP6996P_RS19540	COG2211	Major facilitator Superfamily
XcfCFBP6996P_RS19545	COG1609	Transcriptional regulator
XcfCFBP6996P_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS19555	COG2851	Citrate transporter
XcfCFBP6996P_RS19575	COG0642	Histidine kinase
XcfCFBP6996P_RS19585	COG2197	response regulator
XcfCFBP6996P_RS19600	COG0667	Aldo Keto reductase
XcfCFBP6996P_RS19605	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS19630	COG1301	dicarboxylic acid transport
XcfCFBP6996P_RS19635	COG0281	malic enzyme
XcfCFBP6996P_RS19635	COG0280	phosphate acetyltransferase
XcfCFBP6996P_RS19660	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6996P_RS19665	COG1519	Transferase
XcfCFBP6996P_RS19670	COG1538	Outer membrane efflux protein
XcfCFBP6996P_RS19675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6996P_RS19695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP6996P_RS19705	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP6996P_RS19710	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6996P_RS19715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP6996P_RS19735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP6996P_RS19740	COG0405	Gamma-glutamyltransferase
XcfCFBP6996P_RS19745	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS19760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP6996P_RS19765	COG3710	Transcriptional regulator
XcfCFBP6996P_RS19785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP6996P_RS19795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP6996P_RS19810	COG0563	adenylate kinase activity
XcfCFBP6996P_RS19815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6996P_RS19825	COG3781	membrane
XcfCFBP6996P_RS19830	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6996P_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6996P_RS19845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6996P_RS19850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP6996P_RS19880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6996P_RS19895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6996P_RS19915	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP6996P_RS19920	COG1773	rubredoxin
XcfCFBP6996P_RS19925	COG2912	Transglutaminase-like superfamily
XcfCFBP6996P_RS19935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP6996P_RS19945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP6996P_RS19965	COG3079	Belongs to the UPF0149 family
XcfCFBP6996P_RS19970	COG0006	proline dipeptidase activity
XcfCFBP6996P_RS19980	COG0006	proline dipeptidase activity
XcfCFBP6996P_RS19995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP6996P_RS20000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP6996P_RS20010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP6996P_RS20015	COG1561	YicC-like family, N-terminal region
XcfCFBP6996P_RS20030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6996P_RS20035	COG0583	DNA-binding transcription factor activity
XcfCFBP6996P_RS20050	COG2271	Major facilitator Superfamily
XcfCFBP6996P_RS20065	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP6996P_RS20075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP6996P_RS20100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP6996P_RS20130	COG0714	Associated with various cellular activities
XcfCFBP6996P_RS20150	COG2304	oxidoreductase activity
XcfCFBP6996P_RS20160	COG1301	dicarboxylic acid transport
XcfCFBP6996P_RS20165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP6996P_RS20175	COG4773	Receptor
XcfCFBP6996P_RS20180	COG0739	heme binding
XcfCFBP6996P_RS20185	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP6996P_RS20220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP6996P_RS20225	COG4149	molybdate abc transporter
XcfCFBP6996P_RS20230	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP6996P_RS20235	COG3453	Protein conserved in bacteria
XcfCFBP6996P_RS20235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6996P_RS20245	COG3047	cAMP biosynthetic process
XcfCFBP6996P_RS20250	COG3047	cAMP biosynthetic process
XcfCFBP6996P_RS20260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP6996P_RS20285	COG0126	phosphoglycerate kinase activity
XcfCFBP6996P_RS20295	COG0469	pyruvate kinase activity
XcfCFBP6996P_RS20310	COG3588	fructose-bisphosphate aldolase
XcfCFBP6996P_RS20315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP6996P_RS20330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6996P_RS20330	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6996P_RS20350	COG0784	Response regulator, receiver
XcfCFBP6996P_RS20350	COG2198	Histidine kinase
XcfCFBP6996P_RS20350	COG2205	protein histidine kinase activity
XcfCFBP6996P_RS20370	COG0175	sulfate reduction
XcfCFBP6996P_RS20375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP6996P_RS20380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6996P_RS20385	COG0175	sulfate reduction
XcfCFBP6996P_RS20390	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP6996P_RS20390	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP6996P_RS20400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6996P_RS20405	COG0308	aminopeptidase N
XcfCFBP6996P_RS20415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6996P_RS20425	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6996P_RS20430	COG3250	beta-galactosidase activity
XcfCFBP6996P_RS20440	COG1609	Transcriptional regulator
XcfCFBP6996P_RS20450	COG1970	mechanosensitive ion channel activity
XcfCFBP6996P_RS20475	COG3273	potassium ion transport
XcfCFBP6996P_RS20475	COG0471	metal ion transport
XcfCFBP6996P_RS20480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP6996P_RS20485	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP6996P_RS20530	COG0189	ligase activity
XcfCFBP6996P_RS20540	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6996P_RS20590	COG3328	transposase activity
XcfCFBP6996P_RS20600	COG0237	dephospho-CoA kinase activity
XcfCFBP6996P_RS20605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP6996P_RS20665	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6996P_RS20670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP6996P_RS20685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6996P_RS20685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP6996P_RS20695	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6996P_RS20700	COG0564	pseudouridine synthase activity
XcfCFBP6996P_RS20715	COG3011	Protein conserved in bacteria
XcfCFBP6996P_RS20720	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS20740	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6996P_RS20745	COG1877	trehalose-phosphatase activity
XcfCFBP6996P_RS20785	COG2827	Endonuclease containing a URI domain
XcfCFBP6996P_RS20790	COG4771	TonB-dependent receptor
XcfCFBP6996P_RS20795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6996P_RS20800	COG0667	Aldo Keto reductase
XcfCFBP6996P_RS20805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP6996P_RS20810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6996P_RS20815	COG1116	anion transmembrane transporter activity
XcfCFBP6996P_RS20820	COG0542	response to heat
XcfCFBP6996P_RS20825	COG4206	TonB-dependent receptor
XcfCFBP6996P_RS20850	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6996P_RS20860	COG1492	cobalamin metabolic process
XcfCFBP6996P_RS20870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP6996P_RS20900	COG0019	diaminopimelate decarboxylase activity
XcfCFBP6996P_RS20915	COG4264	IucA IucC family
XcfCFBP6996P_RS20925	COG4772	TonB-dependent receptor
XcfCFBP6996P_RS20935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6996P_RS20935	COG4651	solute:proton antiporter activity
XcfCFBP6996P_RS20975	COG0488	(ABC) transporter
XcfCFBP6996P_RS21015	COG0477	Major facilitator Superfamily
XcfCFBP6996P_RS21030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP6996P_RS21045	COG0217	transcriptional regulatory protein
XcfCFBP6996P_RS21050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP6996P_RS21055	COG0632	four-way junction helicase activity
XcfCFBP6996P_RS21060	COG3158	transport of potassium into the cell
XcfCFBP6996P_RS21065	COG2255	four-way junction helicase activity
XcfCFBP6996P_RS21070	COG0824	Thioesterase
XcfCFBP6996P_RS21080	COG0848	biopolymer transport protein
XcfCFBP6996P_RS21090	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6996P_RS21095	COG2885	chlorophyll binding
XcfCFBP6996P_RS21105	COG0602	queuosine metabolic process
XcfCFBP6996P_RS21115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP6996P_RS21120	COG3920	Histidine kinase
XcfCFBP6996P_RS21140	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS21175	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP6996P_RS21180	COG0783	Belongs to the Dps family
XcfCFBP6996P_RS21185	COG1643	Atp-dependent helicase
XcfCFBP6996P_RS21195	COG0837	glucose binding
XcfCFBP6996P_RS21210	COG0535	radical SAM domain protein
XcfCFBP6996P_RS21215	COG0535	radical SAM domain protein
XcfCFBP6996P_RS21220	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP6996P_RS21225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP6996P_RS21235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6996P_RS21250	COG1216	Glycosyl transferase, family 2
XcfCFBP6996P_RS21255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6996P_RS21265	COG1199	ATP-dependent helicase activity
XcfCFBP6996P_RS21275	COG1397	ADP-ribosylglycohydrolase
XcfCFBP6996P_RS21285	COG0189	ligase activity
XcfCFBP6996P_RS21300	COG0835	chemotaxis
XcfCFBP6996P_RS21305	COG0840	transmembrane signaling receptor activity
XcfCFBP6996P_RS21310	COG0643	Histidine kinase
XcfCFBP6996P_RS21310	COG2198	Histidine kinase
XcfCFBP6996P_RS21310	COG0784	Response regulator, receiver
XcfCFBP6996P_RS21335	COG1446	asparaginase
XcfCFBP6996P_RS21340	COG3142	Participates in the control of copper homeostasis
XcfCFBP6996P_RS21380	COG3537	Alpha-1,2-mannosidase
XcfCFBP6996P_RS21390	COG1486	melibiose metabolic process
XcfCFBP6996P_RS21400	COG0531	amino acid
XcfCFBP6996P_RS21415	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6996P_RS21430	COG3858	chitin binding
XcfCFBP6996P_RS21430	COG1388	LysM domain
XcfCFBP6996P_RS21445	COG0837	glucose binding
XcfCFBP6996P_RS21450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP6996P_RS21460	COG0494	nUDIX hydrolase
XcfCFBP6996P_RS21465	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP6996P_RS21470	COG3956	TIGRFAM MazG family protein
XcfCFBP6996P_RS21475	COG1742	UPF0060 membrane protein
XcfCFBP6996P_RS21490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP6996P_RS21495	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP6996P_RS21520	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6996P_RS21530	COG1309	transcriptional regulator
XcfCFBP6996P_RS21535	COG4771	TonB-dependent receptor
XcfCFBP6996P_RS21545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP6996P_RS21550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6996P_RS21555	COG0463	Glycosyl transferase, family 2
XcfCFBP6996P_RS21560	COG0516	GMP reductase activity
XcfCFBP6996P_RS21560	COG0517	IMP dehydrogenase activity
XcfCFBP6996P_RS21565	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP6996P_RS21570	COG1272	protein, Hemolysin III
XcfCFBP6996P_RS21575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP6996P_RS21580	COG0739	heme binding
XcfCFBP6996P_RS21585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6996P_RS21590	COG0626	cystathionine gamma-synthase activity
XcfCFBP6996P_RS21595	COG0460	homoserine dehydrogenase
XcfCFBP6996P_RS21595	COG0527	aspartate kinase activity
XcfCFBP6996P_RS21610	COG1760	l-serine dehydratase
XcfCFBP6996P_RS21630	COG2353	YceI-like domain
XcfCFBP6996P_RS21655	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS21660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP6996P_RS21670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP6996P_RS21675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP6996P_RS21680	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP6996P_RS21690	COG1842	Phage shock protein A
XcfCFBP6996P_RS21715	COG0754	glutathionylspermidine amidase activity
XcfCFBP6996P_RS21725	COG2814	Major facilitator Superfamily
XcfCFBP6996P_RS21835	COG0531	amino acid
XcfCFBP6996P_RS21840	COG2197	response regulator
XcfCFBP6996P_RS21865	COG3328	transposase activity
XcfCFBP6996P_RS21880	COG1113	amino acid transport
XcfCFBP6996P_RS21890	COG1271	oxidase subunit
XcfCFBP6996P_RS21895	COG1294	oxidase, subunit
XcfCFBP6996P_RS21905	COG2239	Acts as a magnesium transporter
XcfCFBP6996P_RS21910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6996P_RS21915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6996P_RS21925	COG1660	Displays ATPase and GTPase activities
XcfCFBP6996P_RS21930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP6996P_RS21935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6996P_RS21950	COG1137	ATPase activity
XcfCFBP6996P_RS21955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP6996P_RS21965	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP6996P_RS21975	COG0271	Belongs to the BolA IbaG family
XcfCFBP6996P_RS21980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP6996P_RS22000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP6996P_RS22010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP6996P_RS22020	COG0628	permease
XcfCFBP6996P_RS22040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP6996P_RS22045	COG3178	'Phosphotransferase
XcfCFBP6996P_RS22060	COG1555	photosystem II stabilization
XcfCFBP6996P_RS22070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6996P_RS22075	COG1477	protein flavinylation
XcfCFBP6996P_RS22100	COG3128	pkhd-type hydroxylase
XcfCFBP6996P_RS22110	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP6996P_RS22120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP6996P_RS22125	COG0719	Fe-S assembly protein
XcfCFBP6996P_RS22130	COG0396	ATPase activity
XcfCFBP6996P_RS22135	COG0719	Fe-S assembly protein
XcfCFBP6996P_RS22140	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP6996P_RS22150	COG0693	protein deglycase activity
XcfCFBP6996P_RS22170	COG0739	heme binding
XcfCFBP6996P_RS22185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP6996P_RS22215	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6996P_RS22225	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6996P_RS22230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6996P_RS22235	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6996P_RS22240	COG1764	response to oxidative stress
XcfCFBP6996P_RS22250	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6996P_RS22425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP6996P_RS22430	COG4691	Plasmid stability protein
XcfCFBP6996P_RS22435	COG1487	ribonuclease activity
XcfCFBP6996P_RS22505	COG3846	protein secretion by the type IV secretion system
XcfCFBP6996P_RS22515	COG3451	type IV secretory pathway VirB4
XcfCFBP6996P_RS22530	COG4962	Type ii secretion system protein e
XcfCFBP6996P_RS22555	COG3328	transposase activity