locus-tag	class	description
XapA_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XapA_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XapA_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XapA_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_RS00030	ENOG4108K0D	peptidase, M48
XapA_RS00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XapA_RS00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_RS00105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XapA_RS00125	ENOG4105CN1	protease
XapA_RS00130	ENOG41063SB	peptidase
XapA_RS00140	ENOG4107VAM	peptidase, m28
XapA_RS00180	ENOG4105DQ4	alcohol dehydrogenase
XapA_RS00185	ENOG4105BZ8	glutamate synthase
XapA_RS00190	ENOG4105CBC	glutamate synthase
XapA_RS00220	ENOG4105EXG	Transcriptional regulator
XapA_RS00240	ENOG4105D3Q	Sugar transferase
XapA_RS00245	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
XapA_RS00270	ENOG4107RA4	Glycosyl transferase (Group 1
XapA_RS00305	ENOG4105CMR	udp-glucose 4-epimerase
XapA_RS00320	ENOG4105BZ1	(ABC) transporter
XapA_RS00350	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
XapA_RS00450	ENOG4108I5C	dEAD DEAH box helicase
XapA_RS00455	ENOG4108UT2	hemolysin iii
XapA_RS00475	ENOG4107FW0	short-chain dehydrogenase reductase
XapA_RS00480	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XapA_RS00495	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
XapA_RS00535	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_RS00545	ENOG4105CSH	Transporter
XapA_RS00550	ENOG4105DR8	Membrane
XapA_RS00560	ENOG4105Y49	secretion protein, HlyD family
XapA_RS00565	ENOG4105ZQC	membrane protein AaeX
XapA_RS00575	ENOG4105EUJ	GTP cyclohydrolase i
XapA_RS00595	ENOG4105EJ9	Membrane
XapA_RS00600	ENOG4105K5B	UPF0225 protein
XapA_RS00610	ENOG4105DSB	aldose 1-epimerase
XapA_RS00635	ENOG4105DKK	Benzoate
XapA_RS00665	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XapA_RS00685	ENOG4105C4R	Atp-dependent dna helicase
XapA_RS00690	ENOG4105KNA	-acetyltransferase
XapA_RS00700	ENOG4108YXG	UPF0502 protein
XapA_RS00710	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XapA_RS00715	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XapA_RS00720	ENOG4105QV4	Tryptophan halogenase
XapA_RS00735	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS00750	ENOG4105E55	glycerol-3-phosphate acyltransferase
XapA_RS00785	ENOG4105RKW	reductase (By
XapA_RS00870	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XapA_RS00875	ENOG4105CG3	alpha amylase, catalytic region
XapA_RS00880	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_RS00895	ENOG4105EBR	Carboxylesterase
XapA_RS00910	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XapA_RS00920	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XapA_RS00925	ENOG4105DSG	hydrolase family 43
XapA_RS00930	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS00940	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XapA_RS00945	ENOG4105CHR	reductase
XapA_RS00955	ENOG4107TDE	lipolytic protein G-D-S-L family
XapA_RS00970	ENOG4105MIR	Phenylalanine 4-monooxygenase
XapA_RS00975	ENOG4108YXU	transcriptional regulator AsnC family
XapA_RS00980	ENOG4105CNM	Receptor
XapA_RS00985	ENOG4105D78	K07001 NTE family protein
XapA_RS00995	ENOG4105DKW	ABC transporter
XapA_RS01010	ENOG4108IJ8	ABC transporter
XapA_RS01015	ENOG4105E90	ABC transporter
XapA_RS01080	ENOG4105D1F	ATP-binding protein
XapA_RS01085	ENOG4105M4E	phosphohistidine phosphatase, SixA
XapA_RS01095	ENOG4107RZC	phospholipase d
XapA_RS01105	ENOG4105KA0	thioesterase Superfamily protein
XapA_RS01145	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XapA_RS01155	ENOG4105C5F	glutamine synthetase
XapA_RS01165	ENOG4105BZU	Histidine kinase
XapA_RS01170	ENOG4105CUX	Signal transduction histidine kinase
XapA_RS01175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_RS01180	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_RS01185	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_RS01200	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_RS01235	ENOG4107YZP	Rhodanese domain protein
XapA_RS01240	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XapA_RS01245	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XapA_RS01300	ENOG4105D00	flagellar biosynthetic protein flhB
XapA_RS01305	ENOG4105D7B	Flagellar biosynthesis protein flha
XapA_RS01310	ENOG4108JQA	flagellar
XapA_RS01315	ENOG4105CGA	flagellar basal-body rod protein FlgG
XapA_RS01325	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_RS01330	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_RS01345	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XapA_RS01350	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XapA_RS01390	ENOG410822I	Flagellar hook capping protein
XapA_RS01395	ENOG4105BZE	flagellar hook protein, FlgE
XapA_RS01405	ENOG4105DD5	Flagellar motor switch protein
XapA_RS01415	ENOG4105CN7	Flagellar biosynthetic protein FliP
XapA_RS01420	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS01425	ENOG4105C7K	acetolactate synthase
XapA_RS01430	ENOG4108TQ9	Histidine kinase
XapA_RS01435	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_RS01455	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XapA_RS01470	ENOG4105E2T	synthase III
XapA_RS01475	ENOG4107R3N	Filamentation induced by cAMP protein fic
XapA_RS01480	ENOG4108J2P	Alpha beta hydrolase fold
XapA_RS01485	ENOG4105PI0	Ferredoxin
XapA_RS01490	ENOG410680H	amp-dependent synthetase and ligase
XapA_RS01495	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XapA_RS01510	ENOG4105CPF	Cell wall formation (By similarity)
XapA_RS01520	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XapA_RS01530	ENOG4105DR9	pseudouridine synthase
XapA_RS01540	ENOG4108YZN	class I peptide chain release factor
XapA_RS01550	ENOG4105D44	asparaginase
XapA_RS01555	ENOG4105DGW	oligopeptidase A
XapA_RS01590	ENOG4107R11	Transcriptional regulator
XapA_RS01595	ENOG4107QP3	malate synthase g
XapA_RS01605	ENOG4105BZU	Histidine kinase
XapA_RS01645	ENOG4107QX3	carboxylase
XapA_RS01650	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_RS01655	ENOG4108RZE	Tetr family transcriptional regulator
XapA_RS01710	ENOG4105CKI	cobalamin synthesis protein
XapA_RS01730	ENOG4105D6Z	AFG1 family ATPase
XapA_RS01735	ENOG4105K56	Transcriptional regulator
XapA_RS01740	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XapA_RS01770	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XapA_RS01785	ENOG4108R99	pseudouridine synthase
XapA_RS01800	ENOG4105CQ7	ATP-dependent helicase
XapA_RS01805	ENOG4108W15	Protein of unknown function (DUF1456)
XapA_RS01810	ENOG4105VT2	5-hydroxyisourate hydrolase
XapA_RS01815	ENOG4105E1J	oxidoreductase
XapA_RS01835	ENOG4105C5R	Aminotransferase
XapA_RS01845	ENOG4105EQ2	LysR family Transcriptional regulator
XapA_RS01850	ENOG4107RTG	Major Facilitator superfamily
XapA_RS01860	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XapA_RS01870	ENOG4105DU0	nucleoside hydrolase
XapA_RS01880	ENOG4105C7N	Xanthine uracil vitamin C permease
XapA_RS01900	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_RS01905	ENOG4105F8V	Hydrolase, tatD family
XapA_RS01925	ENOG4106NZI	LysR family Transcriptional regulator
XapA_RS01930	ENOG4105D94	Major Facilitator Superfamily
XapA_RS01945	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XapA_RS01950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XapA_RS01970	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XapA_RS01975	ENOG4105EB3	Histidine kinase
XapA_RS01980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_RS01985	ENOG4105BZS	acriflavin resistance protein
XapA_RS01990	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_RS02005	ENOG4105WPN	DNA integration recombination invertion protein
XapA_RS02010	ENOG4105DZ2	Transcriptional regulator
XapA_RS02015	ENOG4108UZX	fmn reductase
XapA_RS02030	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
XapA_RS02045	ENOG4105ECR	NmrA family
XapA_RS02095	ENOG4105C01	Dihydroxy-acid dehydratase
XapA_RS02110	ENOG4108Z0R	Transferase
XapA_RS02120	ENOG4105D2S	major facilitator superfamily
XapA_RS02125	ENOG4105CPI	Metal Dependent Phosphohydrolase
XapA_RS02160	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XapA_RS02170	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XapA_RS02175	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XapA_RS02180	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XapA_RS02185	ENOG4105E98	transcriptional regulator DeoR family
XapA_RS02215	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_RS02230	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XapA_RS02235	ENOG4105F2Z	3-oxoadipate enol-lactonase
XapA_RS02240	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XapA_RS02250	ENOG4107HP6	Transcriptional regulator
XapA_RS02265	ENOG4105MH3	Protein of unknown function (DUF2490)
XapA_RS02270	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XapA_RS02305	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XapA_RS02310	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XapA_RS02320	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XapA_RS02325	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XapA_RS02330	ENOG41081UC	Inherit from COG: Competence protein
XapA_RS02335	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XapA_RS02405	ENOG4105VS8	Flagellar biosynthetic protein fliq
XapA_RS02425	ENOG4108HR8	type iii secretion
XapA_RS02445	ENOG4107Y59	type iii secretion
XapA_RS02460	ENOG4108JIR	Flagellum-specific ATP synthase
XapA_RS02470	ENOG4108TN6	type iii secretion
XapA_RS02485	ENOG4105FTC	Lytic transglycosylase catalytic
XapA_RS02500	ENOG4105EGS	Mechanosensitive ion channel
XapA_RS02505	ENOG4107RES	phosphoglycerol transferase I
XapA_RS02520	ENOG4105CKW	Inner membrane protein yedI
XapA_RS02530	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XapA_RS02535	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_RS02540	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_RS02565	ENOG4105K4T	epimerase
XapA_RS02570	ENOG4107ZQV	short-chain dehydrogenase reductase
XapA_RS02605	ENOG4105BZS	acriflavin resistance protein
XapA_RS02610	ENOG4105CHR	reductase
XapA_RS02625	ENOG4105C1J	atp-dependent rna helicase
XapA_RS02640	ENOG4105CPP	Dehydrogenase, E1 component
XapA_RS02645	ENOG4107RUY	(E1 component), alpha subunit
XapA_RS02660	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XapA_RS02665	ENOG4105DUX	Transporter
XapA_RS02680	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XapA_RS02690	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XapA_RS02710	ENOG4105KJM	monovalent cation h antiporter subunit g
XapA_RS02715	ENOG4105W4C	monovalent cation H antiporter subunit F
XapA_RS02725	ENOG4107R4Z	monovalent cation h antiporter subunit d
XapA_RS02730	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XapA_RS02735	ENOG4105D65	subunit l
XapA_RS02760	ENOG4105NVB	glycoside hydrolase, family 19
XapA_RS02780	ENOG4105C8V	SAICAR synthetase
XapA_RS02785	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XapA_RS02800	ENOG4105KD7	acetyltransferase
XapA_RS02805	ENOG4107TE5	Lipid kinase
XapA_RS02810	ENOG4105CRQ	synthase (Component I)
XapA_RS02820	ENOG4105DDQ	anthranilate synthase
XapA_RS02830	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XapA_RS02835	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XapA_RS02845	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XapA_RS02850	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XapA_RS02860	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XapA_RS02870	ENOG4108UJD	30S ribosomal protein S9
XapA_RS02885	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XapA_RS02895	ENOG4108UQY	Iron-storage protein
XapA_RS02900	ENOG4105BZU	Histidine kinase
XapA_RS02925	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XapA_RS02945	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XapA_RS02960	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
XapA_RS02975	ENOG4105EM2	membrane
XapA_RS02985	ENOG4105C12	Phosphoribosylglycinamide synthetase
XapA_RS02995	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XapA_RS03000	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XapA_RS03005	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XapA_RS03010	ENOG41077RS	Phosphatase
XapA_RS03035	ENOG4108HPI	phosphatidate Cytidylyltransferase
XapA_RS03040	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XapA_RS03065	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XapA_RS03085	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XapA_RS03095	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XapA_RS03100	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XapA_RS03105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XapA_RS03110	ENOG4105VF7	tolerance protein
XapA_RS03125	ENOG4105VV6	START domain-containing protein
XapA_RS03140	ENOG4105E1F	short-chain dehydrogenase reductase
XapA_RS03150	ENOG4108K8S	endonuclease I
XapA_RS03160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XapA_RS03175	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XapA_RS03200	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XapA_RS03205	ENOG4105EX9	Membrane
XapA_RS03225	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XapA_RS03230	ENOG4108YYC	ycei family
XapA_RS03260	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XapA_RS03275	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XapA_RS03295	ENOG4105DRR	Transcriptional regulator, GntR family
XapA_RS03335	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XapA_RS03375	ENOG4107GJV	short-chain dehydrogenase reductase
XapA_RS03390	ENOG4105PDP	Short chain dehydrogenase
XapA_RS03400	ENOG4105CHF	Glutathione S-transferase
XapA_RS03425	ENOG4105EYF	MMPL domain protein
XapA_RS03435	ENOG4105C5Z	peptidase
XapA_RS03445	ENOG4107QS8	(LipO)protein
XapA_RS03455	ENOG4105BZU	Histidine kinase
XapA_RS03480	ENOG4105DFI	Membrane
XapA_RS03485	ENOG4105F87	Dehydratase
XapA_RS03515	ENOG4105E53	ec 3.2.1.28
XapA_RS03575	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS03580	ENOG4106R7G	Glycoside hydrolase family 5
XapA_RS03585	ENOG4105CHH	sulfate transporter
XapA_RS03595	ENOG4105BZU	Histidine kinase
XapA_RS03615	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XapA_RS03625	ENOG4108HRK	Histidine kinase
XapA_RS03630	ENOG4108NEV	two component transcriptional regulator, LytTR family
XapA_RS03635	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XapA_RS03695	ENOG4105WD1	Membrane
XapA_RS03705	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XapA_RS03715	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XapA_RS03720	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XapA_RS03725	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XapA_RS03750	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XapA_RS03755	ENOG41064RH	membrane protein YliF
XapA_RS03760	ENOG4105CD8	aminopeptidase N
XapA_RS03795	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XapA_RS03810	ENOG4107QW3	Sucrose phosphorylase
XapA_RS03825	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS03830	ENOG4105CHR	reductase
XapA_RS03835	ENOG4105D4T	Citrate transporter
XapA_RS03855	ENOG4105DHQ	Histidine kinase
XapA_RS03860	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XapA_RS03870	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_RS03890	ENOG4105CPC	Aldo Keto reductase
XapA_RS03900	ENOG4105F04	LysR family Transcriptional regulator
XapA_RS03910	ENOG4105CSH	Transporter
XapA_RS03920	ENOG4105CQZ	Histidine kinase
XapA_RS03930	ENOG4105CK2	sodium dicarboxylate symporter
XapA_RS03935	ENOG4105C6K	Malic enzyme
XapA_RS03960	ENOG4105D1S	lipid A biosynthesis
XapA_RS03965	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XapA_RS03970	ENOG4105DFG	type I secretion outer membrane protein
XapA_RS03975	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XapA_RS03990	ENOG4108MP6	LysR family Transcriptional regulator
XapA_RS03995	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XapA_RS04000	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XapA_RS04005	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XapA_RS04010	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XapA_RS04015	ENOG4105C7B	Threonine dehydratase
XapA_RS04030	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XapA_RS04040	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS04055	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XapA_RS04060	ENOG4108M3R	transcriptional activator CadC
XapA_RS04065	ENOG4105ECQ	AraC Family Transcriptional Regulator
XapA_RS04090	ENOG4105F0N	pyrophosphate phospho-hydrolase
XapA_RS04100	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XapA_RS04125	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XapA_RS04130	ENOG4105DFU	Cell wall formation (By similarity)
XapA_RS04140	ENOG4105FFC	UPF0187 protein
XapA_RS04145	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XapA_RS04165	ENOG4105EYW	Ion transport protein
XapA_RS04170	ENOG4105C8Y	Acetylornithine aminotransferase
XapA_RS04200	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_RS04210	ENOG41061ZR	Transcriptional regulator
XapA_RS04215	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XapA_RS04230	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XapA_RS04235	ENOG4105VCQ	rubredoxin
XapA_RS04240	ENOG41063JG	Transcriptional regulator
XapA_RS04250	ENOG4105E66	phosphoriboisomerase A
XapA_RS04260	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XapA_RS04270	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XapA_RS04285	ENOG4107RAQ	aminopeptidase
XapA_RS04295	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XapA_RS04310	ENOG4105CSA	Coproporphyrinogen iii oxidase
XapA_RS04315	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XapA_RS04325	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XapA_RS04330	ENOG4105DSJ	YicC domain protein
XapA_RS04335	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XapA_RS04345	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
XapA_RS04350	ENOG4105CHR	reductase
XapA_RS04355	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XapA_RS04370	ENOG4105TW1	Carbohydrate-selective porin OprB
XapA_RS04385	ENOG4105DKT	Transcriptional regulator
XapA_RS04390	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
XapA_RS04395	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XapA_RS04400	ENOG4105KME	endoribonuclease L-psp
XapA_RS04405	ENOG4105CB5	ATP-dependent DNA helicase recG
XapA_RS04410	ENOG4105DU0	nucleoside hydrolase
XapA_RS04435	ENOG4108JQC	penicillin-binding protein 1A
XapA_RS04465	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_RS04485	ENOG4107QVM	von Willebrand factor, type A
XapA_RS04495	ENOG4105CK2	sodium dicarboxylate symporter
XapA_RS04500	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XapA_RS04505	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
XapA_RS04510	ENOG4105CNM	Receptor
XapA_RS04520	ENOG4105DR5	peptidase
XapA_RS04530	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XapA_RS04565	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XapA_RS04570	ENOG4105E0C	molybdate abc transporter
XapA_RS04575	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XapA_RS04580	ENOG4107S76	domain protein
XapA_RS04590	ENOG4105EIF	outer membrane protein W
XapA_RS04595	ENOG4105EIF	outer membrane protein W
XapA_RS04610	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XapA_RS04635	ENOG4105BZA	Phosphoglycerate kinase
XapA_RS04645	ENOG4105CA9	Pyruvate kinase
XapA_RS04650	ENOG4107R1Y	fructose-bisphosphate aldolase
XapA_RS04655	ENOG4108UVJ	appr-1-p processing domain protein
XapA_RS04670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XapA_RS04675	ENOG4107R11	Transcriptional regulator
XapA_RS04690	ENOG4105BZU	Histidine kinase
XapA_RS04710	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XapA_RS04715	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XapA_RS04720	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_RS04725	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XapA_RS04730	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XapA_RS04735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_RS04740	ENOG4105BZS	acriflavin resistance protein
XapA_RS04790	ENOG4105EIB	trna rrna methyltransferase
XapA_RS04820	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS04830	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XapA_RS04860	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XapA_RS04870	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XapA_RS04915	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XapA_RS04925	ENOG4105ETX	regulatoR
XapA_RS04930	ENOG4105BZU	Histidine kinase
XapA_RS05045	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
XapA_RS05065	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XapA_RS05070	ENOG4107T4Z	adenosine kinase
XapA_RS05080	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XapA_RS05095	ENOG4105CNI	cell division protein FtsW
XapA_RS05105	ENOG4105CVE	Lytic murein transglycosylase
XapA_RS05110	ENOG4105K6T	rare lipoprotein A
XapA_RS05120	ENOG4105DZ1	carboxypeptidase
XapA_RS05135	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XapA_RS05140	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XapA_RS05145	ENOG4105CN1	protease
XapA_RS05155	ENOG4105EGI	Transcriptional regulator
XapA_RS05200	ENOG4108J5G	6-phosphogluconate dehydrogenase
XapA_RS05205	ENOG4105D9R	oxidoreductase
XapA_RS05210	ENOG4105W4M	Transport-associated protein
XapA_RS05215	ENOG4105BZU	Histidine kinase
XapA_RS05225	ENOG4105BZU	Histidine kinase
XapA_RS05280	ENOG4105GVR	general secretion pathway protein D
XapA_RS05285	ENOG4107QHF	type ii secretion system protein e
XapA_RS05290	ENOG4105D7Q	type ii secretion system
XapA_RS05295	ENOG4108VAU	general secretion pathway protein G
XapA_RS05300	ENOG4105VWV	general secretion pathway protein h
XapA_RS05305	ENOG4105X5Z	General secretion pathway protein I
XapA_RS05315	ENOG4108RTD	type II secretion system protein K
XapA_RS05340	ENOG4105CNT	hydrolase family 2
XapA_RS05365	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS05370	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XapA_RS05375	ENOG4105CE4	GlcNAc 6-P deacetylase
XapA_RS05385	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XapA_RS05390	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XapA_RS05395	ENOG4105C26	Dehydrogenase
XapA_RS05400	ENOG4105C94	Transporter
XapA_RS05415	ENOG4108Z33	Thiol disulfide Interchange Protein
XapA_RS05425	ENOG4106RE7	Cytochrome
XapA_RS05430	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XapA_RS05435	ENOG4105CY0	Metallo-Beta-Lactamase
XapA_RS05455	ENOG4105JJR	Histidine kinase
XapA_RS05485	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XapA_RS05500	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XapA_RS05505	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XapA_RS05520	ENOG4105C5H	ABC transporter
XapA_RS05530	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XapA_RS05535	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XapA_RS05545	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XapA_RS05560	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XapA_RS05565	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XapA_RS05570	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XapA_RS05575	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XapA_RS05600	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XapA_RS05605	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XapA_RS05610	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
XapA_RS05615	ENOG4105C08	Histidine kinase
XapA_RS05620	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XapA_RS05660	ENOG4105CQB	FAD linked oxidase domain protein
XapA_RS05665	ENOG4105S2T	inner membrane protein YbcI
XapA_RS05670	ENOG41082RQ	UPF0102 protein
XapA_RS05710	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XapA_RS05715	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XapA_RS05720	ENOG4105CJN	penicillin-binding protein
XapA_RS05725	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XapA_RS05730	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XapA_RS05735	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XapA_RS05745	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XapA_RS05750	ENOG4105DFU	Cell wall formation (By similarity)
XapA_RS05755	ENOG4105CPF	Cell wall formation (By similarity)
XapA_RS05760	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XapA_RS05765	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XapA_RS05770	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XapA_RS05775	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_RS05790	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XapA_RS05795	ENOG4105M6F	mutator MutT protein
XapA_RS05805	ENOG4105SYT	Methylenetetrahydrofolate reductase
XapA_RS05890	ENOG4105DXX	methyltransferase
XapA_RS05895	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XapA_RS05905	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XapA_RS05950	ENOG4105D6F	Phosphatase
XapA_RS05965	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
XapA_RS05970	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XapA_RS05980	ENOG4108RVA	ribokinase
XapA_RS05985	ENOG4105D9N	nucleoside
XapA_RS05995	ENOG4105CPC	Aldo Keto reductase
XapA_RS06005	ENOG4105D05	Receptor
XapA_RS06025	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_RS06040	ENOG4105E2B	Taurine dioxygenase
XapA_RS06050	ENOG4108I0Y	(ABC) transporter
XapA_RS06055	ENOG4108UJV	acyl-CoA thioesterase i
XapA_RS06065	ENOG4105DHQ	Histidine kinase
XapA_RS06085	ENOG41080IJ	Diacylglycerol kinase
XapA_RS06100	ENOG4107RZC	phospholipase d
XapA_RS06105	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_RS06110	ENOG4105BZU	Histidine kinase
XapA_RS06115	ENOG4105BZU	Histidine kinase
XapA_RS06120	ENOG4108V3W	Chemotaxis protein, CheW
XapA_RS06125	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS06130	ENOG4105CBS	Chea signal transduction histidine kinase
XapA_RS06140	ENOG4108JA2	transcriptioN-repair coupling factor
XapA_RS06150	ENOG4105D6S	protein involved in catabolism of external DNA
XapA_RS06160	ENOG4105EB3	Histidine kinase
XapA_RS06165	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XapA_RS06175	ENOG4105CT7	inner membrane cred family protein
XapA_RS06200	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XapA_RS06205	ENOG4105MYN	Zinc uptake regulation protein
XapA_RS06215	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_RS06220	ENOG4105BZS	acriflavin resistance protein
XapA_RS06225	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_RS06240	ENOG4105CF7	AraC family transcriptional regulator
XapA_RS06250	ENOG4105CC0	LysR family Transcriptional regulator
XapA_RS06255	ENOG4105F27	Major Facilitator
XapA_RS06300	ENOG4105UGU	tonB-dependent Receptor
XapA_RS06325	ENOG4105CMQ	Chloride channel
XapA_RS06340	ENOG4105D03	DNA-3-methyladenine glycosylase II
XapA_RS06390	ENOG4105BZU	Histidine kinase
XapA_RS06395	ENOG4105FE9	pseudouridine synthase
XapA_RS06420	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XapA_RS06425	ENOG4105FQP	Beta-lactamase
XapA_RS06435	ENOG4105BZU	Histidine kinase
XapA_RS06440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XapA_RS06445	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_RS06475	ENOG4105BZ1	(ABC) transporter
XapA_RS06520	ENOG4105WG9	Conserved Protein
XapA_RS06555	ENOG4107QR8	Thioredoxin
XapA_RS06565	ENOG4105C8T	Leucyl-tRNA synthetase
XapA_RS06580	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XapA_RS06595	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XapA_RS06615	ENOG4105MPN	Membrane
XapA_RS06620	ENOG4108Z03	MAF-like protein
XapA_RS06625	ENOG4105C03	ribonuclease
XapA_RS06630	ENOG4105QD6	exported protein
XapA_RS06640	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XapA_RS06645	ENOG4105N42	UPF0307 protein
XapA_RS06650	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XapA_RS06665	ENOG4106RHG	Yeca family
XapA_RS06685	ENOG4108C33	Resolvase
XapA_RS06695	ENOG4105CTB	Polyprenyl synthetase
XapA_RS06700	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XapA_RS06705	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XapA_RS06715	ENOG4105G6Z	alkaline phosphatase
XapA_RS06725	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XapA_RS06735	ENOG4105K4H	Nlp p60 protein
XapA_RS06740	ENOG4105K4H	Nlp p60 protein
XapA_RS06745	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
XapA_RS06755	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XapA_RS06760	ENOG4105DC8	reductase
XapA_RS06785	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_RS06795	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_RS06860	ENOG4105CNA	YD repeat protein
XapA_RS06895	ENOG4105CMM	transposase
XapA_RS06915	ENOG4105CNT	hydrolase family 2
XapA_RS06920	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XapA_RS06935	ENOG4105C26	Dehydrogenase
XapA_RS06940	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_RS06945	ENOG4105E39	Enoyl-CoA hydratase
XapA_RS06950	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XapA_RS06970	ENOG4105EMN	RNA polymerase sigma factor
XapA_RS06980	ENOG4105C0H	protease
XapA_RS06985	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XapA_RS06990	ENOG4105C3F	Signal peptidase i
XapA_RS07000	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XapA_RS07005	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XapA_RS07020	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XapA_RS07035	ENOG4107ZXU	DSBA oxidoreductase
XapA_RS07040	ENOG4108QDE	fad dependent oxidoreductase
XapA_RS07045	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XapA_RS07050	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XapA_RS07055	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XapA_RS07060	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XapA_RS07070	ENOG4105VEQ	Cold shock protein
XapA_RS07085	ENOG4107QRT	dEAD DEAH box helicase
XapA_RS07090	ENOG4107T0X	DNA ligase
XapA_RS07100	ENOG4107T0X	DNA ligase
XapA_RS07135	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_RS07160	ENOG4108VKG	metal-dependent hydrolase
XapA_RS07175	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XapA_RS07195	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XapA_RS07205	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XapA_RS07220	ENOG4105F27	Major Facilitator
XapA_RS07260	ENOG4105M4H	endoribonuclease L-psp
XapA_RS07265	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XapA_RS07280	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XapA_RS07305	ENOG4105K6V	RNA polymerase
XapA_RS07325	ENOG4108R3D	Electron transport complex
XapA_RS07335	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XapA_RS07350	ENOG4105DA5	(ABC) transporter
XapA_RS07355	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XapA_RS07360	ENOG4108IQI	permease
XapA_RS07365	ENOG4107QK5	Homocysteine s-methyltransferase
XapA_RS07415	ENOG4108YXA	Membrane
XapA_RS07430	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XapA_RS07440	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XapA_RS07445	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_RS07450	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_RS07455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XapA_RS07460	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_RS07475	ENOG4105DZP	Membrane-associated zinc metalloprotease
XapA_RS07480	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XapA_RS07485	ENOG4105KNE	Phosphatidate cytidylyltransferase
XapA_RS07490	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XapA_RS07495	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XapA_RS07500	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XapA_RS07510	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XapA_RS07515	ENOG4105CE9	30S ribosomal protein S2
XapA_RS07550	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XapA_RS07555	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XapA_RS07565	ENOG4105KUZ	arsenate reductase
XapA_RS07570	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XapA_RS07575	ENOG4105CAQ	asparagine synthetase
XapA_RS07585	ENOG4108ESX	Receptor
XapA_RS07595	ENOG4108UWD	Iron-storage protein
XapA_RS07610	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_RS07630	ENOG4105CW7	secretion protein, HlyD family
XapA_RS07635	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_RS07660	ENOG4105DUX	Transporter
XapA_RS07690	ENOG4105DGW	oligopeptidase A
XapA_RS07700	ENOG4108V06	Glutathione peroxidase
XapA_RS07705	ENOG4105DP0	ferredoxin-NADP reductase
XapA_RS07715	ENOG4107GFK	fumarate
XapA_RS07735	ENOG4105HDD	phospholipase
XapA_RS07745	ENOG4105VEQ	Cold shock protein
XapA_RS07760	ENOG4105CUZ	uba thif-type nad fad binding protein
XapA_RS07765	ENOG4105F8V	Hydrolase, tatD family
XapA_RS07780	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_RS07790	ENOG4108K3A	Glutathione S-transferase
XapA_RS07800	ENOG4105CAQ	asparagine synthetase
XapA_RS07810	ENOG4105CDU	Replicative dna helicase
XapA_RS07815	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XapA_RS07825	ENOG4105CDV	Ompa motb domain protein
XapA_RS07835	ENOG4105CR8	Transcriptional regulator
XapA_RS07870	ENOG4105BZU	Histidine kinase
XapA_RS07880	ENOG4106TD9	Diguanylate cyclase
XapA_RS07910	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XapA_RS07915	ENOG4108Z1B	Cyclase dehydrase
XapA_RS07925	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XapA_RS07930	ENOG41090R7	Ferric uptake
XapA_RS07935	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XapA_RS07940	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XapA_RS07945	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XapA_RS07950	ENOG4105CFG	Acts as a chaperone (By similarity)
XapA_RS07955	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XapA_RS07995	ENOG4105C5Q	Transcriptional regulator
XapA_RS08000	ENOG4105BZ1	(ABC) transporter
XapA_RS08010	ENOG4108URH	decarboxylase
XapA_RS08020	ENOG4105C7S	Dehydrogenase
XapA_RS08025	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XapA_RS08035	ENOG4105EZE	Cupin 4 family protein
XapA_RS08045	ENOG4107QTF	adenylosuccinate lyase
XapA_RS08055	ENOG4105C37	(CBS) domain
XapA_RS08085	ENOG4105CZV	ABC transporter
XapA_RS08090	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XapA_RS08105	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_RS08110	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XapA_RS08115	ENOG41069P5	Protein slyX homolog
XapA_RS08130	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS08140	ENOG4105D7K	pfkb domain protein
XapA_RS08165	ENOG4105C3R	Methionine synthase
XapA_RS08170	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XapA_RS08175	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_RS08180	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_RS08200	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XapA_RS08210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XapA_RS08215	ENOG4105BZU	Histidine kinase
XapA_RS08220	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XapA_RS08230	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XapA_RS08235	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XapA_RS08240	ENOG4105E2Z	phosphate ABC transporter (Permease
XapA_RS08245	ENOG4105C8U	phosphate abc transporter
XapA_RS08250	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XapA_RS08275	ENOG4105CHH	sulfate transporter
XapA_RS08280	ENOG4105CSM	endonuclease III
XapA_RS08290	ENOG4105E39	Enoyl-CoA hydratase
XapA_RS08295	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_RS08300	ENOG4105P8F	nudix hydrolase
XapA_RS08305	ENOG4105KHC	sulfurtransferase
XapA_RS08350	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XapA_RS08375	ENOG4105CJB	Exodeoxyribonuclease I
XapA_RS08385	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XapA_RS08390	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XapA_RS08400	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XapA_RS08405	ENOG41077A9	carbonic anhydrase
XapA_RS08450	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_RS08490	ENOG4105C5S	asparaginyl-tRNA synthetase
XapA_RS08500	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XapA_RS08505	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XapA_RS08510	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XapA_RS08515	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XapA_RS08525	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XapA_RS08535	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_RS08540	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XapA_RS08545	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XapA_RS08560	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XapA_RS08565	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_RS08570	ENOG4105DZG	Dehydrogenase
XapA_RS08580	ENOG4105CGP	Urocanate hydratase
XapA_RS08590	ENOG4105C84	Histidine ammonia-lyase
XapA_RS08595	ENOG4105CI2	imidazolone-5-propionate hydrolase
XapA_RS08635	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XapA_RS08640	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XapA_RS08645	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XapA_RS08655	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XapA_RS08670	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XapA_RS08675	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XapA_RS08680	ENOG4105CC0	LysR family Transcriptional regulator
XapA_RS08705	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS08730	ENOG4105BZU	Histidine kinase
XapA_RS08755	ENOG4105KWW	Biogenesis protein
XapA_RS08760	ENOG4107QX9	Thiol disulfide interChange protein
XapA_RS08765	ENOG4105DA4	cytochrome c-type biogenesis protein
XapA_RS08770	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XapA_RS08780	ENOG41060IM	Heme exporter protein
XapA_RS08795	ENOG4105EMN	RNA polymerase sigma factor
XapA_RS08850	ENOG4105EGZ	biosynthesis protein
XapA_RS08885	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XapA_RS08910	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_RS08915	ENOG4105BZ1	(ABC) transporter
XapA_RS08920	ENOG41079KZ	Major Facilitator Superfamily
XapA_RS08925	ENOG4105DEN	Luciferase family
XapA_RS08955	ENOG4105CJ3	phosphate transporter
XapA_RS08970	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_RS08980	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XapA_RS08985	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XapA_RS08995	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XapA_RS09000	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XapA_RS09005	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XapA_RS09010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XapA_RS09015	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XapA_RS09020	ENOG4108DG9	Smr protein MutS2
XapA_RS09025	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XapA_RS09030	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XapA_RS09035	ENOG4108UM1	dedA family
XapA_RS09040	ENOG4108K5P	(LipO)protein
XapA_RS09050	ENOG4105HBR	Rna-binding protein
XapA_RS09055	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XapA_RS09060	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XapA_RS09065	ENOG4105EEI	dihydropteroate synthase
XapA_RS09070	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XapA_RS09080	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XapA_RS09085	ENOG4107TH8	cina domain protein
XapA_RS09095	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XapA_RS09100	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XapA_RS09110	ENOG4105Y3E	Modulates RecA activity (By similarity)
XapA_RS09115	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XapA_RS09135	ENOG4107SDU	Methyl-accepting chemotaxis
XapA_RS09145	ENOG4105CWB	LysR family transcriptional Regulator
XapA_RS09185	ENOG4108IAB	Phoh family
XapA_RS09190	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XapA_RS09205	ENOG4107TUS	Dihydrodipicolinate synthase
XapA_RS09215	ENOG4108Z4U	Ferredoxin
XapA_RS09220	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XapA_RS09230	ENOG4105CXK	mandelate racemase muconate lactonizing
XapA_RS09235	ENOG4108RTU	Aldolase
XapA_RS09285	ENOG4105CMG	Carbohydrate kinase
XapA_RS09290	ENOG4105C93	Xylose Isomerase
XapA_RS09315	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
XapA_RS09320	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XapA_RS09330	ENOG4105DJ0	Poly(A) Polymerase
XapA_RS09335	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XapA_RS09340	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XapA_RS09345	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XapA_RS09350	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XapA_RS09355	ENOG4107QP8	phosphohexose isomerase
XapA_RS09400	ENOG4105KU2	hydrolase family 5
XapA_RS09405	ENOG4108UYB	regulatoR
XapA_RS09420	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XapA_RS09425	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XapA_RS09455	ENOG4105D4A	Cell wall formation (By similarity)
XapA_RS09460	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XapA_RS09480	ENOG4105C26	Dehydrogenase
XapA_RS09510	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XapA_RS09515	ENOG4106H78	methyltransferase
XapA_RS09520	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XapA_RS09535	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XapA_RS09540	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XapA_RS09545	ENOG4105E08	Glycoside hydrolase, family 9
XapA_RS09550	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XapA_RS09590	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XapA_RS09595	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XapA_RS09600	ENOG4105VIE	preprotein translocase, subunit YajC
XapA_RS09605	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XapA_RS09610	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XapA_RS09650	ENOG4105DM4	PTS System
XapA_RS09655	ENOG4105DE4	1-phosphofructokinase
XapA_RS09660	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XapA_RS09665	ENOG4108M60	Transcriptional regulator
XapA_RS09675	ENOG4105BZS	acriflavin resistance protein
XapA_RS09680	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_RS09690	ENOG4105C7I	Dehydrogenase
XapA_RS09725	ENOG4105W39	Membrane
XapA_RS09740	ENOG4108RCM	Nitroreductase
XapA_RS09745	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
XapA_RS09780	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XapA_RS09880	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XapA_RS09885	ENOG41090A4	Pterin carbinolamine dehydratase
XapA_RS09895	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XapA_RS09900	ENOG4108NST	exported protein
XapA_RS09905	ENOG4105EI2	Pseudouridine synthase
XapA_RS09910	ENOG4105C03	ribonuclease
XapA_RS09920	ENOG4105C72	UPF0176 protein
XapA_RS09930	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_RS09940	ENOG4107QQG	Dehydrogenase
XapA_RS09965	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_RS10050	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XapA_RS10055	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XapA_RS10070	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XapA_RS10075	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XapA_RS10080	ENOG4105BZ1	(ABC) transporter
XapA_RS10095	ENOG4108EC8	DNA internalization-related competence protein ComEC
XapA_RS10105	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_RS10110	ENOG4105D60	lipoprotein releasing system transmembrane protein
XapA_RS10120	ENOG410681N	tpr repeat protein
XapA_RS10125	ENOG4105E33	succinate dehydrogenase
XapA_RS10145	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XapA_RS10170	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XapA_RS10175	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XapA_RS10180	ENOG4105C01	Dihydroxy-acid dehydratase
XapA_RS10185	ENOG4108UHU	Aldolase
XapA_RS10210	ENOG4105N7H	Cytochrome
XapA_RS10255	ENOG4105BZU	Histidine kinase
XapA_RS10260	ENOG4105BZM	domain protein
XapA_RS10285	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XapA_RS10295	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XapA_RS10315	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XapA_RS10345	ENOG4105XMH	SpoVT AbrB domain protein
XapA_RS10410	ENOG4106RHG	Yeca family
XapA_RS10430	ENOG4108C33	Resolvase
XapA_RS10460	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XapA_RS10465	ENOG4108Z6B	deaminase
XapA_RS10470	ENOG4105KST	dependent repressor
XapA_RS10475	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XapA_RS10495	ENOG4107SFI	Major Facilitator superfamily
XapA_RS10520	ENOG4105CHJ	isochorismatase hydrolase
XapA_RS10535	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_RS10555	ENOG4105DND	Transcriptional regulator
XapA_RS10565	ENOG4105EVH	UPF0753 protein
XapA_RS10570	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_RS10575	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XapA_RS10580	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XapA_RS10590	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XapA_RS10600	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XapA_RS10610	ENOG4105ESV	Glycosyl transferase, family 4
XapA_RS10615	ENOG4105CFV	Tetratricopeptide repeat protein
XapA_RS10625	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XapA_RS10630	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XapA_RS10635	ENOG4105CAT	Cytidine monophosphate kinase
XapA_RS10655	ENOG4105DWY	Agmatine deiminase
XapA_RS10685	ENOG4105DRS	transport system, permease
XapA_RS10690	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XapA_RS10720	ENOG4105K9H	YciI-like protein
XapA_RS10725	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XapA_RS10730	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XapA_RS10735	ENOG4105FE9	pseudouridine synthase
XapA_RS10755	ENOG4105CHM	Aminotransferase
XapA_RS10760	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XapA_RS10765	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XapA_RS10770	ENOG41060IM	Heme exporter protein
XapA_RS10780	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XapA_RS10785	ENOG4105DA4	cytochrome c-type biogenesis protein
XapA_RS10795	ENOG4105KWW	Biogenesis protein
XapA_RS10815	ENOG4108JJ8	(ABC) transporter
XapA_RS10820	ENOG4108JJ9	ABC, transporter
XapA_RS10825	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_RS10830	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_RS10840	ENOG4105EKQ	RNA-directed DNA polymerase
XapA_RS10865	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XapA_RS10870	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XapA_RS10880	ENOG4105CH7	arginosuccinase
XapA_RS10885	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XapA_RS10895	ENOG4105CAS	nag kinase
XapA_RS10910	ENOG4105CDH	Citrulline--aspartate ligase
XapA_RS10915	ENOG4105DBV	ornithine carbamoyltransferase
XapA_RS10925	ENOG4105C8N	cysteinyl-tRNA synthetase
XapA_RS10930	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XapA_RS10945	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XapA_RS10950	ENOG4105CD3	dihydroorotase
XapA_RS10975	ENOG4105CPD	ethanolamine ammonia-lyase
XapA_RS10980	ENOG4107FQ9	ethanolamine ammonia-lyase
XapA_RS11045	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XapA_RS11050	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XapA_RS11055	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XapA_RS11065	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XapA_RS11070	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XapA_RS11075	ENOG4105BZU	Histidine kinase
XapA_RS11090	ENOG4105ECY	inositol monophosphatase
XapA_RS11095	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_RS11115	ENOG4105C5H	ABC transporter
XapA_RS11120	ENOG4105C1J	atp-dependent rna helicase
XapA_RS11125	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XapA_RS11130	ENOG4105CNG	UPF0061 protein
XapA_RS11140	ENOG4108RXX	maleylacetoacetate isomerase
XapA_RS11145	ENOG4105VEQ	Cold shock protein
XapA_RS11150	ENOG4108VWS	Yaeq family
XapA_RS11155	ENOG4105CBX	hi0933 family
XapA_RS11190	ENOG4108C33	Resolvase
XapA_RS11200	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XapA_RS11205	ENOG4105CHR	reductase
XapA_RS11230	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XapA_RS11235	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XapA_RS11240	ENOG4105K8N	protein family UPF0079, ATPase
XapA_RS11245	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XapA_RS11250	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XapA_RS11255	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XapA_RS11270	ENOG4105E6M	Sulphatase-modifying factor protein
XapA_RS11310	ENOG4108V3W	Chemotaxis protein, CheW
XapA_RS11315	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS11320	ENOG4108VX5	3-methyladenine DNA glycosylase
XapA_RS11325	ENOG4107QRT	dEAD DEAH box helicase
XapA_RS11345	ENOG4105KB2	stringent starvation protein b
XapA_RS11350	ENOG4107MKT	Stringent starvation protein a
XapA_RS11355	ENOG4105EIX	cytochrome c1
XapA_RS11360	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XapA_RS11375	ENOG4105E4C	Lytic transglycosylase catalytic
XapA_RS11390	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XapA_RS11400	ENOG4105C9A	Phoh family
XapA_RS11410	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XapA_RS11420	ENOG4108JU5	Magnesium and cobalt efflux protein
XapA_RS11440	ENOG4105D38	putrescine abc transporter
XapA_RS11445	ENOG4105F38	ABC transporter, permease
XapA_RS11450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XapA_RS11470	ENOG4107RUE	extracellular solute-binding protein family 1
XapA_RS11475	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XapA_RS11490	ENOG4105CFQ	glutamine synthetase
XapA_RS11495	ENOG4105CJP	fad dependent oxidoreductase
XapA_RS11505	ENOG4105W3S	hemerythrin-like, metal-binding protein
XapA_RS11520	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XapA_RS11525	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XapA_RS11555	ENOG4106BRA	Membrane
XapA_RS11560	ENOG4105BZU	Histidine kinase
XapA_RS11565	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_RS11570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_RS11600	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
XapA_RS11620	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XapA_RS11650	ENOG4108N8X	transition metal ion binding
XapA_RS11690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XapA_RS11700	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XapA_RS11715	ENOG4105CGK	Exodeoxyribonuclease III
XapA_RS11755	ENOG4105D06	uba thif-type nad fad binding protein
XapA_RS11765	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XapA_RS11770	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XapA_RS11775	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XapA_RS11785	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XapA_RS11795	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XapA_RS11815	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_RS11825	ENOG41082MI	Protein CrcB homolog
XapA_RS11830	ENOG4105D1H	recombination factor protein RarA
XapA_RS11840	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XapA_RS11850	ENOG4105CNU	cell division protein FtsK
XapA_RS11855	ENOG4105C3M	thioredoxin reductase
XapA_RS11865	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XapA_RS11875	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XapA_RS11890	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XapA_RS11920	ENOG4105BZU	Histidine kinase
XapA_RS11925	ENOG4105BZU	Histidine kinase
XapA_RS11955	ENOG4108ZC9	flagellar basal-body rod protein flgc
XapA_RS11960	ENOG410822I	Flagellar hook capping protein
XapA_RS11965	ENOG4105BZE	flagellar hook protein, FlgE
XapA_RS11975	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XapA_RS11985	ENOG4105CGA	flagellar basal-body rod protein FlgG
XapA_RS11990	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_RS11995	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_RS12000	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XapA_RS12010	ENOG4105DTJ	flagellar hook-associated protein
XapA_RS12025	ENOG4107W9T	flagellar hook-associated
XapA_RS12030	ENOG4105MQ3	flagellar protein FliS
XapA_RS12050	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS12055	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_RS12100	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XapA_RS12105	ENOG4105CHR	reductase
XapA_RS12145	ENOG4107RGC	Glycosyl transferase, family 2
XapA_RS12150	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XapA_RS12155	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XapA_RS12160	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XapA_RS12170	ENOG4108JIR	Flagellum-specific ATP synthase
XapA_RS12190	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XapA_RS12195	ENOG4105DD5	Flagellar motor switch protein
XapA_RS12200	ENOG4105K0P	flagellar biosynthesis protein
XapA_RS12205	ENOG4105CN7	Flagellar biosynthetic protein FliP
XapA_RS12215	ENOG4105VS8	Flagellar biosynthetic protein fliq
XapA_RS12220	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XapA_RS12225	ENOG4105BZU	Histidine kinase
XapA_RS12245	ENOG4105D00	flagellar biosynthetic protein flhB
XapA_RS12250	ENOG4105D7B	Flagellar biosynthesis protein flha
XapA_RS12255	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XapA_RS12265	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS12270	ENOG4108VYJ	response regulator receiver protein
XapA_RS12295	ENOG4105C4X	radical SAM domain protein
XapA_RS12330	ENOG4105E14	MotA TolQ exbB proton channel
XapA_RS12335	ENOG4105ER2	Ompa motb domain protein
XapA_RS12345	ENOG4108V3W	Chemotaxis protein, CheW
XapA_RS12355	ENOG4108VYJ	response regulator receiver protein
XapA_RS12360	ENOG4105CBS	Chea signal transduction histidine kinase
XapA_RS12365	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12380	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12395	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12400	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12410	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12415	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12425	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12430	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12435	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12440	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12445	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12460	ENOG4108V3W	Chemotaxis protein, CheW
XapA_RS12470	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS12475	ENOG4105BZU	Histidine kinase
XapA_RS12480	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XapA_RS12485	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_RS12490	ENOG4105BZU	Histidine kinase
XapA_RS12495	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XapA_RS12500	ENOG4107QIJ	Aconitate hydratase 2
XapA_RS12515	ENOG4107QM5	aconitate hydratase
XapA_RS12525	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_RS12560	ENOG4105E39	Enoyl-CoA hydratase
XapA_RS12565	ENOG4105BZU	Histidine kinase
XapA_RS12570	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_RS12575	ENOG4105CRK	lysyL-tRNA synthetase
XapA_RS12585	ENOG4105DY9	regulatoR
XapA_RS12640	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XapA_RS12650	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XapA_RS12655	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XapA_RS12665	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XapA_RS12670	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XapA_RS12675	ENOG4108RPX	mosc domain containing protein
XapA_RS12695	ENOG4105CE1	Ferrous iron transport protein b
XapA_RS12715	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XapA_RS12725	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XapA_RS12745	ENOG4105CQB	FAD linked oxidase domain protein
XapA_RS12750	ENOG4108JQ1	Dehydrogenase
XapA_RS12760	ENOG4105CUB	amino acid
XapA_RS12770	ENOG4106S9K	Transcriptional regulator
XapA_RS12825	ENOG4105CUB	amino acid
XapA_RS12830	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XapA_RS12835	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XapA_RS12840	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XapA_RS12855	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XapA_RS12860	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XapA_RS12865	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XapA_RS12870	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XapA_RS12875	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XapA_RS12880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_RS12885	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XapA_RS12890	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XapA_RS12900	ENOG4105CUT	histidyl-tRNA synthetase
XapA_RS12905	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XapA_RS13000	ENOG4107BJW	polysaccharide deacetylase
XapA_RS13150	ENOG4107QTZ	amino acid
XapA_RS13165	ENOG4105DC7	peptidase M24
XapA_RS13175	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XapA_RS13190	ENOG41080HI	glycine oxidase
XapA_RS13195	ENOG4105CTU	Proline racemase
XapA_RS13205	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XapA_RS13215	ENOG4105CEN	a g-specific adenine glycosylase
XapA_RS13220	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XapA_RS13225	ENOG4105CQZ	Histidine kinase
XapA_RS13270	ENOG4105QNF	Outer membrane lipoprotein
XapA_RS13285	ENOG4105CSU	acyl-Coa dehydrogenase
XapA_RS13295	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XapA_RS13315	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XapA_RS13320	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XapA_RS13325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XapA_RS13350	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XapA_RS13360	ENOG4107Y2G	Glycosyl transferase (Group 1
XapA_RS13385	ENOG4105D3Q	Sugar transferase
XapA_RS13405	ENOG4105WJX	transcriptional regulator MERR family
XapA_RS13415	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XapA_RS13420	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XapA_RS13435	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XapA_RS13440	ENOG4105C22	threonyL-tRNA synthetase
XapA_RS13445	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS13490	ENOG4105CMA	conjugation trbi family protein
XapA_RS13525	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XapA_RS13580	ENOG4105EWT	decarboxylase family
XapA_RS13585	ENOG4108KPZ	tonB-dependent Receptor
XapA_RS13595	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XapA_RS13605	ENOG4105M2J	Glutaredoxin
XapA_RS13610	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_RS13615	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XapA_RS13620	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XapA_RS13630	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XapA_RS13640	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XapA_RS13650	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XapA_RS13655	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XapA_RS13660	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XapA_RS13665	ENOG4105CHV	Transcription elongation factor NusA
XapA_RS13670	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XapA_RS13680	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_RS13685	ENOG4105C8S	subunit m
XapA_RS13690	ENOG4105D65	subunit l
XapA_RS13705	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_RS13710	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XapA_RS13715	ENOG4107R0R	NADH dehydrogenase subunit g
XapA_RS13720	ENOG4107QIZ	NADH dehydrogenase
XapA_RS13725	ENOG4105GKE	subunit e
XapA_RS13730	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_RS13735	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XapA_RS13740	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_RS13745	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XapA_RS13760	ENOG4105CP7	Triose-phosphate isomerase
XapA_RS13765	ENOG4107FW0	short-chain dehydrogenase reductase
XapA_RS13780	ENOG4105BZU	Histidine kinase
XapA_RS13795	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XapA_RS13800	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XapA_RS13805	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XapA_RS13815	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XapA_RS13825	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XapA_RS13830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XapA_RS13850	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XapA_RS13855	ENOG4105C5I	Dehydrogenase
XapA_RS13860	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XapA_RS13865	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XapA_RS13875	ENOG4105DJ4	phosphatidylserine decarboxylase
XapA_RS13890	ENOG4105D7A	ATP-binding protein
XapA_RS13895	ENOG4107VIJ	nudix hydrolase
XapA_RS13915	ENOG4108RRZ	Transcription elongation factor GreB
XapA_RS13920	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XapA_RS13935	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XapA_RS13965	ENOG4105ED4	portal protein
XapA_RS14010	ENOG4105NVB	glycoside hydrolase, family 19
XapA_RS14210	ENOG4105DHP	deoxycytidine triphosphate deaminase
XapA_RS14245	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XapA_RS14255	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XapA_RS14260	ENOG4105VEJ	Heat shock protein
XapA_RS14275	ENOG4107QJQ	Mate efflux family protein
XapA_RS14280	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XapA_RS14285	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XapA_RS14290	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XapA_RS14295	ENOG4105K5M	30s ribosomal protein S16
XapA_RS14305	ENOG4107QWG	2-Nitropropane dioxygenase
XapA_RS14310	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XapA_RS14315	ENOG4105CRE	cytochrome C
XapA_RS14320	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XapA_RS14325	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XapA_RS14355	ENOG4105BZU	Histidine kinase
XapA_RS14360	ENOG4105BZU	Histidine kinase
XapA_RS14365	ENOG4107Z5C	methylesterase
XapA_RS14370	ENOG4105C08	Histidine kinase
XapA_RS14375	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XapA_RS14400	ENOG4105BZU	Histidine kinase
XapA_RS14410	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XapA_RS14415	ENOG4105FUA	antagonist
XapA_RS14420	ENOG4107MMM	Anti-sigma-factor antagonist
XapA_RS14430	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XapA_RS14445	ENOG4105KAF	membrAne
XapA_RS14450	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XapA_RS14460	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XapA_RS14465	ENOG4105CCU	oxidase (Subunit III)
XapA_RS14470	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XapA_RS14475	ENOG4105E2S	oxidase) subunit II
XapA_RS14485	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XapA_RS14490	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XapA_RS14495	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XapA_RS14500	ENOG4105DTN	riboflavin biosynthesis protein ribF
XapA_RS14505	ENOG4105CJR	Integral membrane protein (MviN
XapA_RS14515	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XapA_RS14520	ENOG4105K46	50S ribosomal protein l27
XapA_RS14525	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XapA_RS14530	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XapA_RS14535	ENOG4108TGP	Thioesterase superfamily protein
XapA_RS14580	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XapA_RS14590	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XapA_RS14635	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_RS14640	ENOG4105BZU	Histidine kinase
XapA_RS14655	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XapA_RS14660	ENOG4107QMS	site-determining protein
XapA_RS14675	ENOG4105DHQ	Histidine kinase
XapA_RS14680	ENOG4105ETX	regulatoR
XapA_RS14695	ENOG4105DIJ	Phosphoethanolamine transferase
XapA_RS14710	ENOG4105C2C	drug resistance transporter, Bcr CflA
XapA_RS14715	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XapA_RS14720	ENOG4105EBR	Carboxylesterase
XapA_RS14725	ENOG4105CV8	reductase
XapA_RS14755	ENOG4106AXJ	AraC family transcriptional regulator
XapA_RS14815	ENOG4105C3M	thioredoxin reductase
XapA_RS14825	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XapA_RS14830	ENOG4105CWX	Alpha-1,2-mannosidase
XapA_RS14840	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XapA_RS14845	ENOG4105BZP	glycoside hydrolase 15-related
XapA_RS14855	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XapA_RS14895	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
XapA_RS14950	ENOG4108XFH	Transcriptional regulator
XapA_RS14955	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XapA_RS14960	ENOG4105CD8	aminopeptidase N
XapA_RS14965	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XapA_RS14975	ENOG4105EPW	hflc protein
XapA_RS14980	ENOG4107QJR	hflk protein
XapA_RS14985	ENOG4105M3Z	response regulator
XapA_RS15010	ENOG4108JQB	penicillin-binding protein 1C
XapA_RS15030	ENOG4105DN3	alpha-2-macroglobulin domain protein
XapA_RS15050	ENOG4105C7F	AcnD-accessory protein PrpF
XapA_RS15065	ENOG4105YAJ	CopG Arc MetJ
XapA_RS15070	ENOG4108I0Z	Aconitate hydratase
XapA_RS15075	ENOG4105BZN	citrate synthase
XapA_RS15080	ENOG4105CR4	methylisocitrate lyase
XapA_RS15085	ENOG4108JU7	Transcriptional regulator
XapA_RS15105	ENOG4107QRG	dna polymerase iii
XapA_RS15110	ENOG4105HHA	aminodeoxychorismate lyase
XapA_RS15120	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XapA_RS15130	ENOG4105CHR	reductase
XapA_RS15135	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XapA_RS15145	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XapA_RS15150	ENOG4105VGS	50s ribosomal protein l32
XapA_RS15155	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XapA_RS15160	ENOG4108UHJ	MAF-like protein
XapA_RS15190	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_RS15200	ENOG4105F8C	transglutaminase domain-containing protein
XapA_RS15210	ENOG4105K59	histidine triad (HIT) protein
XapA_RS15215	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XapA_RS15220	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XapA_RS15225	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XapA_RS15240	ENOG4108ZAF	Molybdopterin
XapA_RS15245	ENOG4105M00	molybdopterin converting factor, subunit 1
XapA_RS15250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XapA_RS15255	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XapA_RS15260	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XapA_RS15265	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XapA_RS15270	ENOG4105DKP	glycosyl transferase, family 9
XapA_RS15285	ENOG4108ZF3	Phosphatase
XapA_RS15290	ENOG4107RZZ	dna polymerase iii epsilon subunit
XapA_RS15295	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XapA_RS15305	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XapA_RS15310	ENOG41068JE	domain protein
XapA_RS15315	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XapA_RS15340	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XapA_RS15350	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XapA_RS15360	ENOG4105BZU	Histidine kinase
XapA_RS15390	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XapA_RS15400	ENOG4105VW4	glutaredoxin 3
XapA_RS15405	ENOG4105ERG	peptidase m48, ste24p
XapA_RS15410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XapA_RS15415	ENOG4105BZU	Histidine kinase
XapA_RS15420	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XapA_RS15425	ENOG4105C9X	ppx gppa phosphatase
XapA_RS15430	ENOG4105BZF	Glycosyl transferase (Group 1
XapA_RS15435	ENOG4105EYK	Phosphatidylglycerophosphatase B
XapA_RS15440	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XapA_RS15460	ENOG4105ED9	Protein of unknown function (DUF455)
XapA_RS15465	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XapA_RS15480	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XapA_RS15495	ENOG4105CVJ	phosphoglycerate mutase
XapA_RS15525	ENOG4105CPQ	Dehydrogenase
XapA_RS15535	ENOG4108IJ6	ABC transporter
XapA_RS15545	ENOG4108I5D	sulfate abc transporter
XapA_RS15550	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XapA_RS15555	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XapA_RS15565	ENOG4108R99	pseudouridine synthase
XapA_RS15575	ENOG4105CDV	Ompa motb domain protein
XapA_RS15590	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XapA_RS15610	ENOG4108K3A	Glutathione S-transferase
XapA_RS15620	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XapA_RS15625	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XapA_RS15630	ENOG4105CI3	gtp-binding protein typa
XapA_RS15640	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XapA_RS15650	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XapA_RS15670	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XapA_RS15700	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XapA_RS15705	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XapA_RS15720	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XapA_RS15725	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XapA_RS15730	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XapA_RS15740	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XapA_RS15745	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XapA_RS15770	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XapA_RS15780	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XapA_RS15785	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XapA_RS15795	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XapA_RS15800	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XapA_RS15805	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XapA_RS15810	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XapA_RS15815	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XapA_RS15820	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XapA_RS15830	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XapA_RS15835	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XapA_RS15840	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XapA_RS15845	ENOG4108VZM	50s ribosomal protein L10
XapA_RS15850	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XapA_RS15855	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XapA_RS15860	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XapA_RS15865	ENOG4105PM1	preprotein translocase subunit SecE
XapA_RS15875	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XapA_RS15895	ENOG4105C3G	gtp-binding protein
XapA_RS15900	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XapA_RS15905	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XapA_RS15910	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XapA_RS15920	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XapA_RS15925	ENOG4105QVB	outer membrane lipoprotein LolB
XapA_RS15930	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XapA_RS15935	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XapA_RS15940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XapA_RS15960	ENOG4105CSR	polyphosphate kinase 2
XapA_RS15980	ENOG4107S2Z	UPF0761 membrane protein
XapA_RS15985	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XapA_RS16005	ENOG4108Z66	YbaK ebsC protein
XapA_RS16010	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_RS16020	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_RS16030	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XapA_RS16045	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XapA_RS16050	ENOG4105W8H	transhydrogenase (subunit alpha
XapA_RS16070	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XapA_RS16100	ENOG4105C2M	dna polymerase I
XapA_RS16120	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XapA_RS16135	ENOG4105C5Q	Transcriptional regulator
XapA_RS16145	ENOG4105NXH	GreA GreB family elongation factor
XapA_RS16150	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XapA_RS16160	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XapA_RS16175	ENOG4105BZU	Histidine kinase
XapA_RS16195	ENOG4105CX6	glutaminyL-tRNA synthetase
XapA_RS16205	ENOG4105DXC	membrane
XapA_RS16225	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XapA_RS16260	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XapA_RS16270	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_RS16275	ENOG4105DDW	LysR family Transcriptional regulator
XapA_RS16310	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XapA_RS16315	ENOG4105D0A	hydroxylase
XapA_RS16330	ENOG4108WBT	adenosyltransferase
XapA_RS16340	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XapA_RS16345	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XapA_RS16350	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XapA_RS16355	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XapA_RS16360	ENOG4105NWN	ApaG protein
XapA_RS16365	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XapA_RS16375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
XapA_RS16385	ENOG4105DEF	Extracellular solute-binding protein, family 5
XapA_RS16410	ENOG4108UZX	fmn reductase
XapA_RS16415	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
XapA_RS16425	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_RS16430	ENOG4105D7T	ABC transporter
XapA_RS16435	ENOG4107T8P	acyl-Coa dehydrogenase
XapA_RS16440	ENOG4107SM7	Transcriptional regulator
XapA_RS16455	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XapA_RS16460	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XapA_RS16495	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XapA_RS16500	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XapA_RS16510	ENOG4105EUB	pirin domain protein
XapA_RS16525	ENOG4105EUB	pirin domain protein
XapA_RS16530	ENOG4105D22	carbon starvation protein
XapA_RS16535	ENOG4105VCD	cytoplasmic protein
XapA_RS16585	ENOG4107XAN	XdhC and CoxI family
XapA_RS16590	ENOG4105C7W	Xanthine dehydrogenase
XapA_RS16595	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XapA_RS16600	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XapA_RS16615	ENOG4108UUM	single-stranded DNA-binding protein
XapA_RS16620	ENOG4105EAH	synthase
XapA_RS16635	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XapA_RS16650	ENOG4105CFH	Aspartokinase
XapA_RS16655	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XapA_RS16670	ENOG4108Z9K	Osmotically inducible protein
XapA_RS16675	ENOG4105CXT	aspartate transcarbamylase
XapA_RS16680	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XapA_RS16685	ENOG4108UJU	UPF0301 protein
XapA_RS16695	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_RS16705	ENOG4108E16	pectate lyase
XapA_RS16710	ENOG4105CZX	twitching motility protein
XapA_RS16715	ENOG4105CZX	twitching motility protein
XapA_RS16720	ENOG4105DFA	alanine racemase domain protein
XapA_RS16725	ENOG4105II7	pyrroline-5-carboxylate reductase
XapA_RS16735	ENOG4105FAA	peptidase M23
XapA_RS16755	ENOG4108Z0Z	intracellular protease Pfpi family
XapA_RS16775	ENOG4105C3K	feS assembly ATPase SufC
XapA_RS16780	ENOG4105JRK	feS assembly protein SufD
XapA_RS16785	ENOG4105C9B	Cysteine desulfurase
XapA_RS16795	ENOG4105VQD	rieske 2fe-2S domain-containing protein
XapA_RS16800	ENOG4108IU3	tonb-dependent siderophore receptor
XapA_RS16805	ENOG4107E2E	PKHD-type hydroxylase
XapA_RS16830	ENOG4105CJ2	(LipO)protein
XapA_RS16835	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_RS16850	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XapA_RS16865	ENOG4105EHM	Aminoglycoside phosphotransferase
XapA_RS16870	ENOG4108S0S	Nucleotidyl transferase
XapA_RS16880	ENOG4105C02	permease
XapA_RS16890	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XapA_RS16900	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XapA_RS16920	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XapA_RS16930	ENOG4105C2X	Arabinose 5-phosphate isomerase
XapA_RS16935	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XapA_RS16945	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XapA_RS16950	ENOG4108IUZ	ABC transporter
XapA_RS16955	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS16960	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XapA_RS16965	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XapA_RS16970	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XapA_RS16975	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XapA_RS16985	ENOG41080Z8	PHOSPHOCARRIER protein
XapA_RS16990	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XapA_RS17000	ENOG4105CJW	magnesium transporter
XapA_RS17005	ENOG4107UWA	esterase
XapA_RS17015	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_RS17020	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_RS17040	ENOG4105C85	amino acid
XapA_RS17050	ENOG4108NFF	pectate lyase
XapA_RS17075	ENOG4105CUB	amino acid
XapA_RS17095	ENOG4108MHS	Lysyl endopeptidase
XapA_RS17105	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XapA_RS17170	ENOG4108Z4X	TRANSCRIPTIONal
XapA_RS17185	ENOG4106032	Glutathionylspermidine synthase
XapA_RS17210	ENOG4108P9J	Phage shock protein A
XapA_RS17220	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XapA_RS17225	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XapA_RS17230	ENOG4105D49	3-dehydroquinate synthase
XapA_RS17240	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XapA_RS17245	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_RS17250	ENOG4105BZU	Histidine kinase
XapA_RS17255	ENOG4105BZU	Histidine kinase
XapA_RS17265	ENOG4105BZU	Histidine kinase
XapA_RS17270	ENOG4108YYC	ycei family
XapA_RS17290	ENOG4105EJQ	L-serine dehydratase
XapA_RS17305	ENOG4105CFH	Aspartokinase
XapA_RS17310	ENOG4105C28	cystathionine
XapA_RS17315	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XapA_RS17320	ENOG4105DR5	peptidase
XapA_RS17325	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XapA_RS17330	ENOG4108UT2	hemolysin iii
XapA_RS17335	ENOG41066T0	asmA family
XapA_RS17340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XapA_RS17350	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XapA_RS17355	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XapA_RS17365	ENOG4105D05	Receptor
XapA_RS17380	ENOG4108IG5	Transcriptional regulator
XapA_RS17390	ENOG4107QPN	acyl-Coa dehydrogenase
XapA_RS17420	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XapA_RS17425	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XapA_RS17445	ENOG4105KK4	UPF0060 membrane protein
XapA_RS17450	ENOG4105DXN	mazG family
XapA_RS17455	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XapA_RS17460	ENOG4107RK2	ADP-ribose diphosphatase NudE
XapA_RS17470	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XapA_RS17475	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XapA_RS17490	ENOG4105VRS	hydrolase family 18
XapA_RS17510	ENOG4108JJA	ABC, transporter
XapA_RS17545	ENOG4105CWX	Alpha-1,2-mannosidase
XapA_RS17585	ENOG4106N3A	copper homeostasis protein cutc
XapA_RS17605	ENOG4105D9U	N-acetyltransferase
XapA_RS17625	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS17635	ENOG4105M3Z	response regulator
XapA_RS17640	ENOG4108UNF	response regulator
XapA_RS17645	ENOG4105D7Z	glutathione synthase
XapA_RS17655	ENOG41065RQ	ADP-ribosylation crystallin J1
XapA_RS17660	ENOG41072GX	Peptidase M22 Glycoprotease
XapA_RS17665	ENOG4105DVT	helicase
XapA_RS17675	ENOG4105BZ4	penicillin-binding protein
XapA_RS17695	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XapA_RS17700	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
XapA_RS17705	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XapA_RS17710	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XapA_RS17715	ENOG4105Z85	coenzyme PQQ synthesis
XapA_RS17720	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XapA_RS17750	ENOG4105CQ7	ATP-dependent helicase
XapA_RS17765	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XapA_RS17800	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS17820	ENOG410903D	sensor protein
XapA_RS17825	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XapA_RS17835	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XapA_RS17845	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XapA_RS17850	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XapA_RS17865	ENOG4105E02	MotA TolQ exbB proton channel
XapA_RS17870	ENOG4107YD3	Thioesterase
XapA_RS17875	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XapA_RS17885	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XapA_RS17890	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XapA_RS17895	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XapA_RS17900	ENOG4105CDY	transcriptional regulatory protein
XapA_RS17915	ENOG4105C9M	aspartyl-trna synthetase
XapA_RS17930	ENOG4108ISG	Major Facilitator
XapA_RS17940	ENOG4105HSS	phospholipase C
XapA_RS17960	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_RS17970	ENOG4105C5H	ABC transporter
XapA_RS17975	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_RS17995	ENOG4107RNH	Outer membrane receptor FepA
XapA_RS18010	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XapA_RS18035	ENOG4105GAV	receptor
XapA_RS18060	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XapA_RS18090	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XapA_RS18095	ENOG4108YZT	Adenosylcobinamide kinase
XapA_RS18100	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XapA_RS18105	ENOG4105EFT	decarboxylase
XapA_RS18115	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XapA_RS18130	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_RS18135	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XapA_RS18140	ENOG4105E2Y	ABC, transporter
XapA_RS18145	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_RS18150	ENOG4105GVF	(ABC) transporter
XapA_RS18155	ENOG4105CPC	Aldo Keto reductase
XapA_RS18165	ENOG4107ZSV	Receptor
XapA_RS18180	ENOG41082IR	Excinuclease ABC C subunit domain protein
XapA_RS18215	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_RS18225	ENOG4108K4C	ec 3.1.3.12
XapA_RS18230	ENOG4105BZP	glycoside hydrolase 15-related
XapA_RS18235	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XapA_RS18240	ENOG4105DZG	Dehydrogenase
XapA_RS18250	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS18255	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XapA_RS18270	ENOG4105C34	Pseudouridine synthase
XapA_RS18275	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XapA_RS18285	ENOG4105C4K	Nad synthetase
XapA_RS18295	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XapA_RS18300	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XapA_RS18305	ENOG4107TUY	Histidine kinase
XapA_RS18310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_RS18320	ENOG4107QHF	type ii secretion system protein e
XapA_RS18330	ENOG4107QHF	type ii secretion system protein e
XapA_RS18345	ENOG4105D7Q	type ii secretion system
XapA_RS18350	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XapA_RS18355	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XapA_RS18365	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
XapA_RS18370	ENOG4108JJA	ABC, transporter
XapA_RS18375	ENOG4105CHM	Aminotransferase
XapA_RS18425	ENOG41069H0	dihydroorotase EC 3.5.2.3
XapA_RS18430	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XapA_RS18465	ENOG4108RMV	DegV Family
XapA_RS18470	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XapA_RS18500	ENOG4105EJG	cellulose synthase
XapA_RS18505	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
XapA_RS18510	ENOG4107EEX	Cellulose synthase regulator protein
XapA_RS18515	ENOG4107QZ7	Cellulose synthase catalytic subunit
XapA_RS18530	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XapA_RS18595	ENOG4106S9K	Transcriptional regulator
XapA_RS18610	ENOG4105GVR	general secretion pathway protein D
XapA_RS18620	ENOG410678M	general secretion pathway protein M
XapA_RS18625	ENOG41090VX	general secretion pathway protein L
XapA_RS18630	ENOG4105UV2	general secretion pathway protein K
XapA_RS18635	ENOG41069G9	General secretion pathway protein J
XapA_RS18645	ENOG4105WMT	general secretion pathway protein h
XapA_RS18655	ENOG4105D7Q	type ii secretion system
XapA_RS18665	ENOG4107QHF	type ii secretion system protein e
XapA_RS18670	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_RS18675	ENOG4105EUR	Domain-Containing protein
XapA_RS18680	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_RS18685	ENOG4105EUR	Domain-Containing protein
XapA_RS18690	ENOG4108ETH	Formylglycinamide ribotide synthetase
XapA_RS18700	ENOG4105T95	Thiol disulfide interChange protein
XapA_RS18710	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XapA_RS18725	ENOG4108K5H	permease YjgP YjgQ family protein
XapA_RS18735	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XapA_RS18750	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XapA_RS18765	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_RS18770	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
XapA_RS18790	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XapA_RS18800	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XapA_RS18805	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XapA_RS18820	ENOG4105DHJ	ABC, transporter
XapA_RS18825	ENOG4108SNX	Mammalian cell entry related domain protein
XapA_RS18840	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XapA_RS18860	ENOG4107QKV	phosphomannomutase
XapA_RS18865	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XapA_RS18875	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XapA_RS18880	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XapA_RS18895	ENOG4105BZJ	Electron transfer flavoprotein
XapA_RS18900	ENOG4105C10	Electron transfer flavoprotein
XapA_RS18915	ENOG4105IQ5	FAD linked oxidase domain protein
XapA_RS18930	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
XapA_RS18975	ENOG4105EY8	ABC transporter
XapA_RS18985	ENOG4105C28	cystathionine
XapA_RS19010	ENOG4105CZX	twitching motility protein
XapA_RS19015	ENOG4108RXX	maleylacetoacetate isomerase
XapA_RS19030	ENOG4105C1J	atp-dependent rna helicase
XapA_RS19040	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_RS19050	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XapA_RS19060	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XapA_RS19080	ENOG4105NIV	Esterase
XapA_RS19085	ENOG4107RNH	Outer membrane receptor FepA
XapA_RS19090	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XapA_RS19095	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XapA_RS19100	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XapA_RS19115	ENOG4105DGW	oligopeptidase A
XapA_RS19130	ENOG4105E3B	Multicopper oxidase
XapA_RS19170	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XapA_RS19175	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XapA_RS19180	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_RS19185	ENOG4107RBB	ABC transporter, permease
XapA_RS19190	ENOG4107RBB	ABC transporter, permease
XapA_RS19205	ENOG4105BZU	Histidine kinase
XapA_RS19210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XapA_RS19225	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XapA_RS19230	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XapA_RS19235	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XapA_RS19240	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XapA_RS19245	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_RS19250	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_RS19255	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_RS19260	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XapA_RS19280	ENOG4107QN2	dihydrolipoyl dehydrogenase
XapA_RS19290	ENOG4107QSN	dihydrolipoamide acetyltransferase
XapA_RS19330	ENOG4105D01	(LipO)protein
XapA_RS19335	ENOG4108UMI	ABC transporter, permease
XapA_RS19340	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XapA_RS19345	ENOG4108EHX	EamA-like transporter family
XapA_RS19350	ENOG4108VPT	UPF0234 protein
XapA_RS19360	ENOG4105BZU	Histidine kinase
XapA_RS19380	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XapA_RS19385	ENOG4107YBY	Hydrolase
XapA_RS19390	ENOG4105I08	Pseudouridine synthase
XapA_RS19395	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XapA_RS19415	ENOG4105BZU	Histidine kinase
XapA_RS19435	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XapA_RS19440	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XapA_RS19445	ENOG4105EW9	transcriptional regulator AsnC family
XapA_RS19465	ENOG4107RD7	Flagellar Motor Protein, MotA
XapA_RS19470	ENOG4105ER2	Ompa motb domain protein
XapA_RS19500	ENOG4105E3A	(ABC) transporter
XapA_RS19510	ENOG4105EEQ	Na H antiporter
XapA_RS19525	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XapA_RS19535	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XapA_RS19555	ENOG4105CPC	Aldo Keto reductase
XapA_RS19565	ENOG4106WTF	Glycosyl transferase, family 2
XapA_RS19570	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_RS19590	ENOG4107QTZ	amino acid
XapA_RS19600	ENOG4108VAC	response regulator
XapA_RS19605	ENOG4105C2F	Histidine kinase
XapA_RS19630	ENOG4108Z9Z	response to DNA damage stimulus
XapA_RS19635	ENOG4105WEF	catalase
XapA_RS19655	ENOG4105BZU	Histidine kinase
XapA_RS19670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_RS19685	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_RS19690	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_RS19710	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XapA_RS19715	ENOG4105CMR	udp-glucose 4-epimerase
XapA_RS19745	ENOG4105BZ1	(ABC) transporter
XapA_RS19770	ENOG4105E2A	Dehydrogenase
XapA_RS19830	ENOG4105CIG	ABC transporter
XapA_RS19845	ENOG4108UQ8	endoribonuclease L-psp
XapA_RS19860	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_RS19875	ENOG4105HEI	LysR family (Transcriptional regulator
XapA_RS19880	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XapA_RS19955	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS19960	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XapA_RS19965	ENOG4105D1S	lipid A biosynthesis
XapA_RS19975	ENOG4108Z7F	N-acetyltransferase
XapA_RS20020	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XapA_RS20025	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XapA_RS20030	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XapA_RS20035	ENOG4108WZM	domain protein
XapA_RS20040	ENOG4105C79	DNA protecting protein DprA
XapA_RS20060	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XapA_RS20065	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XapA_RS20080	ENOG4107ZQV	short-chain dehydrogenase reductase
XapA_RS20095	ENOG4105D07	Signal peptide peptidase, SppA
XapA_RS20100	ENOG4107QI1	Mate efflux family protein
XapA_RS20120	ENOG4105C25	Primosomal protein n'
XapA_RS20125	ENOG4108TGY	Glutathione S-transferase
XapA_RS20150	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_RS20155	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XapA_RS20160	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_RS20165	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XapA_RS20170	ENOG4105CAK	Cell division ATP-binding protein ftsE
XapA_RS20175	ENOG4105C1J	atp-dependent rna helicase
XapA_RS20185	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XapA_RS20190	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XapA_RS20195	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_RS20205	ENOG4105E9K	Isocitrate dehydrogenase
XapA_RS20220	ENOG4105FB9	CRISPR-associated protein
XapA_RS20240	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
XapA_RS20245	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
XapA_RS20255	ENOG4109066	lysm domain bon superfamily protein
XapA_RS20260	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XapA_RS20265	ENOG4105CH2	amidohydrolase
XapA_RS20270	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_RS20275	ENOG4105BZS	acriflavin resistance protein
XapA_RS20285	ENOG4105E32	cytoplasmic protein
XapA_RS20335	ENOG4108UQS	dipeptidase
XapA_RS20340	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XapA_RS20350	ENOG4105DTQ	mandelate racemase muconate lactonizing
XapA_RS20360	ENOG4105D5Q	Arginine ornithine antiporter
XapA_RS20375	ENOG4108Z12	YiaAB two helix domain-containing protein
XapA_RS20385	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XapA_RS20390	ENOG4107ZVW	dihydroneopterin aldolase
XapA_RS20395	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XapA_RS20405	ENOG4105KTH	gatB Yqey
XapA_RS20415	ENOG4107S2Z	UPF0761 membrane protein
XapA_RS20420	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XapA_RS20425	ENOG4105DHU	Bile acid
XapA_RS20435	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XapA_RS20460	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XapA_RS20465	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XapA_RS20480	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XapA_RS20490	ENOG4105C26	Dehydrogenase
XapA_RS20520	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XapA_RS20525	ENOG4105DR5	peptidase
XapA_RS20530	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XapA_RS20540	ENOG4105EYM	Major Facilitator superfamily
XapA_RS20545	ENOG4105CGK	Exodeoxyribonuclease III
XapA_RS20550	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XapA_RS20560	ENOG4107QJE	Chromosome Partitioning Protein
XapA_RS20565	ENOG4105FA0	parb-like partition protein
XapA_RS20585	ENOG4105CKK	Glycosyl transferase, family 2
XapA_RS20600	ENOG4107QKV	phosphomannomutase
XapA_RS20605	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XapA_RS20610	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XapA_RS20615	ENOG4105W5Q	DNA repair protein (RadC
XapA_RS20620	ENOG4105C75	arginyL-tRNA synthetase
XapA_RS20635	ENOG4105EMU	Dehydrogenase
XapA_RS20640	ENOG4105EXC	Acyl-transferase
XapA_RS20650	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_RS20655	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XapA_RS20660	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XapA_RS20700	ENOG4108YZA	Nitrogen regulatory protein pii
XapA_RS20705	ENOG4105W0Z	cytoplasmic protein
XapA_RS20710	ENOG4105C0P	Mg chelatase subunit ChlI
XapA_RS20725	ENOG41066DG	(EAL) domain protein
XapA_RS20740	ENOG4105EJ2	Transcriptional regulator
XapA_RS20760	ENOG4105E0Y	RtcB Protein
XapA_RS20795	ENOG4105ECP	epimerase
XapA_RS20800	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XapA_RS20805	ENOG4105DHQ	Histidine kinase
XapA_RS20835	ENOG4105C0H	protease
XapA_RS20855	ENOG4105DSF	transport protein
XapA_RS20860	ENOG4107URF	beta-phospho-glucomutase
XapA_RS20865	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XapA_RS20880	ENOG4107VGR	Catalase
XapA_RS20905	ENOG4108S01	response regulator
XapA_RS20910	ENOG4108ZGX	Histidine kinase
XapA_RS20915	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_RS20920	ENOG4105C19	ABC transporter
XapA_RS20945	ENOG4105FDR	Membrane
XapA_RS20965	ENOG4108NNI	Beta-lactamase domain-containing protein
XapA_RS20970	ENOG4105C31	Tryptophanyl-tRNA synthetase
XapA_RS20975	ENOG4105VDW	Csbd family
XapA_RS21080	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XapA_RS21110	ENOG4105EB3	Histidine kinase
XapA_RS21115	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XapA_RS21125	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XapA_RS21145	ENOG4105CH6	catalase
XapA_RS21155	ENOG4105DVT	helicase
XapA_RS21170	ENOG4105E2X	shikimate dehydrogenase
XapA_RS21180	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_RS21205	ENOG4105D52	delta-aminolevulinic acid dehydratase
XapA_RS21240	ENOG4105CYM	Glutathione S-transferase
XapA_RS21280	ENOG4108IUW	ABC transporter
XapA_RS21290	ENOG4105VZ8	Transcriptional regulator
XapA_RS21310	ENOG4105PGM	cation diffusion facilitator family transporter
XapA_RS21320	ENOG4105E0K	tonB-dependent siderophore receptor
XapA_RS21330	ENOG4105ECQ	AraC Family Transcriptional Regulator
XapA_RS21335	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
XapA_RS21340	ENOG4105DA5	(ABC) transporter
XapA_RS21345	ENOG4105E3A	(ABC) transporter
XapA_RS21355	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XapA_RS21390	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XapA_RS21400	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XapA_RS21415	ENOG4105CD5	CoA-binding domain protein
XapA_RS21420	ENOG4105CJW	magnesium transporter
XapA_RS21440	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XapA_RS21445	ENOG4105BZP	glycoside hydrolase 15-related
XapA_RS21465	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XapA_RS21475	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XapA_RS21525	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XapA_RS21530	ENOG4105E9Q	Acyl-transferase
XapA_RS21540	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XapA_RS21570	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XapA_RS21590	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XapA_RS21600	ENOG4105C2M	dna polymerase I
XapA_RS21630	ENOG4107TPY	serine threonine protein kinase
XapA_RS21635	ENOG4108ZF3	Phosphatase
XapA_RS21670	ENOG4105CS6	Rhs element vgr protein
XapA_RS21715	ENOG4105D6F	Phosphatase
XapA_RS21790	ENOG4108WC9	type VI secretion system effector, hcp1 family
XapA_RS21835	ENOG4105C4R	Atp-dependent dna helicase
XapA_RS21850	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_RS21855	ENOG4108KB2	LysR family Transcriptional regulator
XapA_RS21860	ENOG4105JSC	dimethylmenaquinone methyltransferase
XapA_RS21875	ENOG4105KHM	amidohydrolase 2
XapA_RS21905	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_RS21925	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XapA_RS21930	ENOG4105DGI	Alkaline phosphatase
XapA_RS21955	ENOG4105CGK	Exodeoxyribonuclease III
XapA_RS21960	ENOG4105E2R	ROK family
XapA_RS21970	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XapA_RS21980	ENOG4107QN1	sodium solute
XapA_RS21985	ENOG41062QD	Membrane
XapA_RS21995	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XapA_RS22035	ENOG4105DSG	hydrolase family 43
XapA_RS22055	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XapA_RS22060	ENOG4105ERH	Fumarylacetoacetate hydrolase
XapA_RS22070	ENOG4105DIA	mandelate racemase muconate lactonizing
XapA_RS22075	ENOG4105QJH	Domain of unknown function (DUF718)
XapA_RS22080	ENOG4105EDR	glucose galactose transporter
XapA_RS22085	ENOG4108K2P	TRANSCRIPTIONal
XapA_RS22095	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XapA_RS22100	ENOG4105BZU	Histidine kinase
XapA_RS22115	ENOG4105E2V	Glycosyltransferase 36
XapA_RS22120	ENOG4105CT4	transporter
XapA_RS22125	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XapA_RS22155	ENOG4105MA0	exported protein
XapA_RS22160	ENOG4105CFU	surface antigen
XapA_RS22220	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XapA_RS22240	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_RS22250	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XapA_RS22255	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XapA_RS22270	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XapA_RS22295	ENOG4105DH7	May be involved in recombination (By similarity)
XapA_RS22300	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XapA_RS22310	ENOG4105C93	Xylose Isomerase
XapA_RS22315	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_RS22330	ENOG4105CXK	mandelate racemase muconate lactonizing
XapA_RS22345	ENOG4105DEI	Mannitol dehydrogenase
XapA_RS22390	ENOG4105EVH	UPF0753 protein
XapA_RS22445	ENOG4108C33	Resolvase
XapA_RS22495	ENOG4106RHG	Yeca family
XapA_RS22515	ENOG4108C33	Resolvase
XapA_RS22535	ENOG41082W1	Cupin 2, conserved barrel domain protein
XapA_RS22550	ENOG4105CGF	Aromatic amino acid aminotransferase
XapA_RS22555	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XapA_RS22585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_RS22625	ENOG4105CSH	Transporter
XapA_RS22635	ENOG4105K63	Thioredoxin
XapA_RS22660	ENOG4105D4Y	metalloprotease
XapA_RS22680	ENOG41067RQ	csbd family
XapA_RS22780	ENOG4108SIC	Transcriptional regulator
XapA_RS22790	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XapA_RS22845	ENOG4105F2I	Transposase
XapA_RS22865	ENOG4107QKA	exodeoxyribonuclease V beta
XapA_RS22870	ENOG4105DSY	exodeoxyribonuclease V, gamma
XapA_RS22885	ENOG4105DHJ	ABC, transporter
XapA_RS22890	ENOG4105CY3	ABC transporter, permease
XapA_RS22895	ENOG4107PE3	Mammalian cell entry related domain protein
XapA_RS22910	ENOG410903C	(LipO)protein
XapA_RS22920	ENOG4108V06	Glutathione peroxidase
XapA_RS22930	ENOG4107QSV	RmuC domain protein
XapA_RS22935	ENOG4105CIS	alcohol dehydrogenase
XapA_RS22940	ENOG4105EJC	lysr family transcriptional regulator
XapA_RS22955	ENOG4108TGY	Glutathione S-transferase
XapA_RS22965	ENOG4105CUB	amino acid
XapA_RS22980	ENOG4105NRM	Membrane
XapA_RS23020	ENOG4105DR4	Methyltransferase
XapA_RS23030	ENOG4105DU1	integral membrane protein, terc
XapA_RS23045	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XapA_RS23060	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XapA_RS23065	ENOG4108ZJ4	polysaccharide deacetylase
XapA_RS23070	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XapA_RS23075	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
XapA_RS23170	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
XapA_RS23285	ENOG4105C26	Dehydrogenase
XapA_RS23350	ENOG4108NSC	Pfam:DUF88
XapA_RS23410	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
XapA_RS23485	ENOG4105C26	Dehydrogenase
XapA_RS23525	ENOG4105C0H	protease
XapA_RS23820	ENOG4105CMA	conjugation trbi family protein